ORF_ID e_value Gene_name EC_number CAZy COGs Description
MEGJNCCF_00001 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
MEGJNCCF_00002 7.1e-59 ypbB 5.1.3.1 S Helix-turn-helix domain
MEGJNCCF_00003 2e-128 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MEGJNCCF_00004 5.9e-12 M Lysin motif
MEGJNCCF_00005 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MEGJNCCF_00006 7.5e-83 lytH 3.5.1.28 M Ami_3
MEGJNCCF_00007 3.5e-153 phoH T phosphate starvation-inducible protein PhoH
MEGJNCCF_00008 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MEGJNCCF_00009 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MEGJNCCF_00010 1.3e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MEGJNCCF_00011 4.5e-90 recO L Involved in DNA repair and RecF pathway recombination
MEGJNCCF_00012 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
MEGJNCCF_00013 4.5e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEGJNCCF_00014 1.4e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
MEGJNCCF_00015 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEGJNCCF_00016 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MEGJNCCF_00017 9.1e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
MEGJNCCF_00018 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
MEGJNCCF_00019 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MEGJNCCF_00020 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEGJNCCF_00022 4.8e-23 K Acetyltransferase (GNAT) domain
MEGJNCCF_00023 6.2e-112 natA S Domain of unknown function (DUF4162)
MEGJNCCF_00024 2.3e-85 natB CP ABC-type Na efflux pump, permease component
MEGJNCCF_00025 1.2e-91 EG EamA-like transporter family
MEGJNCCF_00026 1.7e-79 yjjH S Calcineurin-like phosphoesterase
MEGJNCCF_00027 1.1e-186 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MEGJNCCF_00028 2.4e-40 6.3.3.2 S ASCH
MEGJNCCF_00029 7.8e-71 lepB 3.4.21.89 U Signal peptidase, peptidase S26
MEGJNCCF_00030 2.2e-117 degV S EDD domain protein, DegV family
MEGJNCCF_00031 3.1e-40 K Transcriptional regulator
MEGJNCCF_00032 1.2e-196 FbpA K Fibronectin-binding protein
MEGJNCCF_00033 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEGJNCCF_00034 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEGJNCCF_00035 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MEGJNCCF_00036 1e-39 ypaA S Protein of unknown function (DUF1304)
MEGJNCCF_00038 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MEGJNCCF_00039 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MEGJNCCF_00040 0.0 dnaE 2.7.7.7 L DNA polymerase
MEGJNCCF_00041 4.3e-15 S Protein of unknown function (DUF2929)
MEGJNCCF_00042 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEGJNCCF_00043 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MEGJNCCF_00044 3.7e-41 XK27_04120 S Putative amino acid metabolism
MEGJNCCF_00045 2.9e-154 iscS 2.8.1.7 E Aminotransferase class V
MEGJNCCF_00046 7.2e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MEGJNCCF_00048 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MEGJNCCF_00049 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MEGJNCCF_00050 5.5e-160 nhaC C Na H antiporter NhaC
MEGJNCCF_00051 7e-127 corA P CorA-like Mg2+ transporter protein
MEGJNCCF_00052 4.3e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MEGJNCCF_00053 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
MEGJNCCF_00054 3.6e-150 S Tetratricopeptide repeat protein
MEGJNCCF_00055 3.8e-136 EG EamA-like transporter family
MEGJNCCF_00056 4.2e-73 alkD L DNA alkylation repair enzyme
MEGJNCCF_00057 1.9e-183 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MEGJNCCF_00058 4.8e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MEGJNCCF_00059 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
MEGJNCCF_00060 2.5e-149 EGP Sugar (and other) transporter
MEGJNCCF_00063 1.8e-38
MEGJNCCF_00064 3.8e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MEGJNCCF_00065 6.2e-21 S Family of unknown function (DUF5322)
MEGJNCCF_00066 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
MEGJNCCF_00067 2.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MEGJNCCF_00068 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MEGJNCCF_00070 7.1e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MEGJNCCF_00071 4.5e-171 patA 2.6.1.1 E Aminotransferase
MEGJNCCF_00072 8.6e-115 glcR K DeoR C terminal sensor domain
MEGJNCCF_00073 6.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
MEGJNCCF_00074 9.8e-135 K Transcriptional regulator
MEGJNCCF_00075 2.3e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEGJNCCF_00076 1.5e-84 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MEGJNCCF_00077 5.9e-192 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MEGJNCCF_00078 4.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MEGJNCCF_00079 2.7e-204 pyrP F Permease
MEGJNCCF_00080 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MEGJNCCF_00081 7.3e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MEGJNCCF_00082 5.2e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MEGJNCCF_00083 6.7e-57 3.1.3.18 J HAD-hyrolase-like
MEGJNCCF_00084 1.7e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MEGJNCCF_00085 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEGJNCCF_00086 3.1e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MEGJNCCF_00087 5.8e-118 prmA J Ribosomal protein L11 methyltransferase
MEGJNCCF_00088 7.6e-43 XK27_03960 S Protein of unknown function (DUF3013)
MEGJNCCF_00089 1.5e-143 iunH2 3.2.2.1 F nucleoside hydrolase
MEGJNCCF_00090 6.4e-12
MEGJNCCF_00091 2.2e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEGJNCCF_00092 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
MEGJNCCF_00093 9.3e-129 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MEGJNCCF_00094 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEGJNCCF_00095 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MEGJNCCF_00096 9.1e-43 yodB K Transcriptional regulator, HxlR family
MEGJNCCF_00097 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MEGJNCCF_00098 5.9e-87 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEGJNCCF_00101 1.7e-15
MEGJNCCF_00103 5.8e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MEGJNCCF_00104 2.3e-34 S Repeat protein
MEGJNCCF_00105 4e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MEGJNCCF_00106 1.1e-202 M Exporter of polyketide antibiotics
MEGJNCCF_00107 3.3e-129 yjjC V ATPases associated with a variety of cellular activities
MEGJNCCF_00108 2.3e-81 K Bacterial regulatory proteins, tetR family
MEGJNCCF_00109 5.8e-205 G PTS system Galactitol-specific IIC component
MEGJNCCF_00110 2.1e-209 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MEGJNCCF_00111 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEGJNCCF_00112 6.3e-76 dprA LU DNA protecting protein DprA
MEGJNCCF_00113 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEGJNCCF_00114 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MEGJNCCF_00115 3.6e-24 yozE S Belongs to the UPF0346 family
MEGJNCCF_00116 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MEGJNCCF_00117 7.2e-79 ypmR E GDSL-like Lipase/Acylhydrolase
MEGJNCCF_00119 4.8e-102 S Aldo keto reductase
MEGJNCCF_00120 2.4e-35 K helix_turn_helix, mercury resistance
MEGJNCCF_00121 8.6e-135 yvgN C Aldo keto reductase
MEGJNCCF_00122 3.2e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MEGJNCCF_00123 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEGJNCCF_00124 8.5e-276 yfmR S ABC transporter, ATP-binding protein
MEGJNCCF_00125 1.9e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MEGJNCCF_00126 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MEGJNCCF_00127 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEGJNCCF_00128 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
MEGJNCCF_00130 5.4e-56 yqeY S YqeY-like protein
MEGJNCCF_00131 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MEGJNCCF_00132 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MEGJNCCF_00135 1.3e-99 epsJ1 M Glycosyltransferase like family 2
MEGJNCCF_00136 1.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
MEGJNCCF_00137 5.6e-93 M transferase activity, transferring glycosyl groups
MEGJNCCF_00138 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEGJNCCF_00139 1.5e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEGJNCCF_00140 4.4e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MEGJNCCF_00141 5.1e-56 dnaD L DnaD domain protein
MEGJNCCF_00142 1e-235 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MEGJNCCF_00143 4e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MEGJNCCF_00144 1.8e-36 ypmB S Protein conserved in bacteria
MEGJNCCF_00145 2.5e-161 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MEGJNCCF_00146 3.4e-76 dinG 2.7.7.7, 3.6.4.12 L the current gene model (or a revised gene model) may contain a frame shift
MEGJNCCF_00147 8.1e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MEGJNCCF_00148 2.8e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MEGJNCCF_00149 3e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MEGJNCCF_00150 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MEGJNCCF_00151 9.3e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
MEGJNCCF_00152 1.4e-155 comEC S Competence protein ComEC
MEGJNCCF_00153 2e-69 comEB 3.5.4.12 F ComE operon protein 2
MEGJNCCF_00154 1.4e-50 comEA L Competence protein ComEA
MEGJNCCF_00155 5.8e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
MEGJNCCF_00156 6.2e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MEGJNCCF_00157 2.2e-20
MEGJNCCF_00159 3.9e-122 K LysR substrate binding domain
MEGJNCCF_00160 2.2e-194 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEGJNCCF_00161 1.5e-93 S Acyltransferase family
MEGJNCCF_00162 1e-152 purD 6.3.4.13 F Belongs to the GARS family
MEGJNCCF_00163 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MEGJNCCF_00164 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MEGJNCCF_00165 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MEGJNCCF_00166 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MEGJNCCF_00167 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEGJNCCF_00168 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEGJNCCF_00169 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEGJNCCF_00170 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MEGJNCCF_00171 2.4e-131 ylbL T Belongs to the peptidase S16 family
MEGJNCCF_00172 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MEGJNCCF_00173 7.2e-74 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MEGJNCCF_00174 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MEGJNCCF_00175 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MEGJNCCF_00176 1.6e-102 ftsW D Belongs to the SEDS family
MEGJNCCF_00177 3.3e-148 manN G system, mannose fructose sorbose family IID component
MEGJNCCF_00178 7e-115 manY G PTS system
MEGJNCCF_00179 6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MEGJNCCF_00180 0.0 typA T GTP-binding protein TypA
MEGJNCCF_00181 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MEGJNCCF_00182 1.7e-23 yktA S Belongs to the UPF0223 family
MEGJNCCF_00183 3.7e-32 1.1.1.27 C L-malate dehydrogenase activity
MEGJNCCF_00184 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEGJNCCF_00185 1.6e-24
MEGJNCCF_00186 5e-23 ykzG S Belongs to the UPF0356 family
MEGJNCCF_00187 1.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEGJNCCF_00188 2.3e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MEGJNCCF_00189 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MEGJNCCF_00190 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MEGJNCCF_00191 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MEGJNCCF_00192 4e-18 S Tetratricopeptide repeat
MEGJNCCF_00193 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEGJNCCF_00194 5.3e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEGJNCCF_00195 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MEGJNCCF_00196 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
MEGJNCCF_00197 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MEGJNCCF_00198 7e-198 yfnA E amino acid
MEGJNCCF_00199 5.7e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
MEGJNCCF_00200 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MEGJNCCF_00201 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MEGJNCCF_00202 1.1e-26 ylqC S Belongs to the UPF0109 family
MEGJNCCF_00203 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MEGJNCCF_00204 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MEGJNCCF_00205 7e-40 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MEGJNCCF_00206 1.3e-147 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MEGJNCCF_00207 1.8e-210 smc D Required for chromosome condensation and partitioning
MEGJNCCF_00208 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MEGJNCCF_00209 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEGJNCCF_00210 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MEGJNCCF_00211 3.3e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MEGJNCCF_00212 2.8e-238 yloV S DAK2 domain fusion protein YloV
MEGJNCCF_00213 4.5e-53 asp S Asp23 family, cell envelope-related function
MEGJNCCF_00214 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MEGJNCCF_00215 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
MEGJNCCF_00216 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MEGJNCCF_00217 3.4e-191 KLT serine threonine protein kinase
MEGJNCCF_00218 3.3e-90 stp 3.1.3.16 T phosphatase
MEGJNCCF_00219 2.2e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MEGJNCCF_00220 5.8e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MEGJNCCF_00221 1.9e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEGJNCCF_00222 4.4e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MEGJNCCF_00223 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MEGJNCCF_00224 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MEGJNCCF_00225 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
MEGJNCCF_00226 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
MEGJNCCF_00227 6.1e-187 rodA D Belongs to the SEDS family
MEGJNCCF_00228 1.8e-12 S Protein of unknown function (DUF2969)
MEGJNCCF_00229 1.2e-26 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MEGJNCCF_00230 3.4e-167 mbl D Cell shape determining protein MreB Mrl
MEGJNCCF_00231 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEGJNCCF_00232 4.1e-15 ywzB S Protein of unknown function (DUF1146)
MEGJNCCF_00233 3.9e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MEGJNCCF_00234 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MEGJNCCF_00235 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MEGJNCCF_00236 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MEGJNCCF_00237 2.7e-57 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEGJNCCF_00238 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MEGJNCCF_00239 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEGJNCCF_00240 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
MEGJNCCF_00241 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MEGJNCCF_00242 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MEGJNCCF_00243 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MEGJNCCF_00244 2.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MEGJNCCF_00245 6.8e-86 tdk 2.7.1.21 F thymidine kinase
MEGJNCCF_00246 4.7e-220 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
MEGJNCCF_00247 3.5e-110 cobQ S glutamine amidotransferase
MEGJNCCF_00248 2e-111 ampC V Beta-lactamase
MEGJNCCF_00249 1.5e-31
MEGJNCCF_00250 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEGJNCCF_00251 9.2e-206 glnP P ABC transporter
MEGJNCCF_00253 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEGJNCCF_00254 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MEGJNCCF_00255 1.5e-274 dnaK O Heat shock 70 kDa protein
MEGJNCCF_00256 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MEGJNCCF_00257 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MEGJNCCF_00258 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MEGJNCCF_00259 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MEGJNCCF_00260 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MEGJNCCF_00261 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEGJNCCF_00262 6.8e-26 ylxQ J ribosomal protein
MEGJNCCF_00263 1.4e-39 ylxR K Protein of unknown function (DUF448)
MEGJNCCF_00264 4.8e-170 nusA K Participates in both transcription termination and antitermination
MEGJNCCF_00265 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
MEGJNCCF_00266 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEGJNCCF_00267 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MEGJNCCF_00268 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MEGJNCCF_00269 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
MEGJNCCF_00270 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MEGJNCCF_00271 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MEGJNCCF_00272 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MEGJNCCF_00273 2.7e-48 S Domain of unknown function (DUF956)
MEGJNCCF_00274 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MEGJNCCF_00276 2.9e-246 glnA 6.3.1.2 E glutamine synthetase
MEGJNCCF_00277 1.3e-45 glnR K Transcriptional regulator
MEGJNCCF_00278 1.2e-204 ynbB 4.4.1.1 P aluminum resistance
MEGJNCCF_00279 1.9e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MEGJNCCF_00280 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
MEGJNCCF_00281 2.7e-46 yqhL P Rhodanese-like protein
MEGJNCCF_00282 4.7e-158 glk 2.7.1.2 G Glucokinase
MEGJNCCF_00283 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
MEGJNCCF_00284 7.4e-70 gluP 3.4.21.105 S Peptidase, S54 family
MEGJNCCF_00285 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MEGJNCCF_00286 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MEGJNCCF_00287 3e-19 D nuclear chromosome segregation
MEGJNCCF_00288 1.2e-74 yciQ P membrane protein (DUF2207)
MEGJNCCF_00289 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MEGJNCCF_00290 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
MEGJNCCF_00291 5.9e-27 yneF S UPF0154 protein
MEGJNCCF_00292 2.2e-30 ynzC S UPF0291 protein
MEGJNCCF_00293 5.5e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MEGJNCCF_00294 4.2e-178 recN L May be involved in recombinational repair of damaged DNA
MEGJNCCF_00295 6.6e-49 argR K Regulates arginine biosynthesis genes
MEGJNCCF_00296 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MEGJNCCF_00297 4.7e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MEGJNCCF_00298 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEGJNCCF_00299 1.2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEGJNCCF_00300 1.7e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MEGJNCCF_00301 1.9e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MEGJNCCF_00302 3.7e-46 yqhY S Asp23 family, cell envelope-related function
MEGJNCCF_00303 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEGJNCCF_00304 1.3e-41 dut S dUTPase
MEGJNCCF_00305 7.2e-117
MEGJNCCF_00306 7.3e-105
MEGJNCCF_00307 4.3e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MEGJNCCF_00308 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MEGJNCCF_00309 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEGJNCCF_00310 7.5e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEGJNCCF_00311 6.9e-121 ytbE S reductase
MEGJNCCF_00312 4.2e-43 ytcD K HxlR-like helix-turn-helix
MEGJNCCF_00313 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
MEGJNCCF_00314 2e-67 ybbL S ABC transporter
MEGJNCCF_00315 8.1e-163 oxlT P Major Facilitator Superfamily
MEGJNCCF_00316 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MEGJNCCF_00317 3.1e-47 S Short repeat of unknown function (DUF308)
MEGJNCCF_00318 1.8e-30 tetR K Transcriptional regulator C-terminal region
MEGJNCCF_00319 1.3e-150 yfeX P Peroxidase
MEGJNCCF_00320 2.5e-16 S Protein of unknown function (DUF3021)
MEGJNCCF_00321 4.5e-39 K LytTr DNA-binding domain
MEGJNCCF_00322 7.6e-113 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MEGJNCCF_00323 2.2e-209 mmuP E amino acid
MEGJNCCF_00324 1.2e-15 psiE S Phosphate-starvation-inducible E
MEGJNCCF_00325 3.7e-155 oppF P Belongs to the ABC transporter superfamily
MEGJNCCF_00326 1.3e-180 oppD P Belongs to the ABC transporter superfamily
MEGJNCCF_00327 5.8e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEGJNCCF_00328 1e-141 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEGJNCCF_00329 9e-202 oppA E ABC transporter, substratebinding protein
MEGJNCCF_00330 9.1e-219 yifK E Amino acid permease
MEGJNCCF_00331 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEGJNCCF_00332 8.2e-55 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
MEGJNCCF_00333 5e-66 pgm3 G phosphoglycerate mutase family
MEGJNCCF_00334 1.5e-251 ctpA 3.6.3.54 P P-type ATPase
MEGJNCCF_00335 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MEGJNCCF_00336 2e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MEGJNCCF_00337 5.6e-150 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MEGJNCCF_00338 1.2e-21 K transcriptional regulator
MEGJNCCF_00339 5e-77 hchA S intracellular protease amidase
MEGJNCCF_00340 2.8e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MEGJNCCF_00341 3.1e-112 lacI3 K helix_turn _helix lactose operon repressor
MEGJNCCF_00342 5.5e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
MEGJNCCF_00343 2e-39 2.7.1.191 G PTS system fructose IIA component
MEGJNCCF_00344 5.4e-123 G PTS system mannose/fructose/sorbose family IID component
MEGJNCCF_00345 4.4e-101 G PTS system sorbose-specific iic component
MEGJNCCF_00346 2e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
MEGJNCCF_00347 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MEGJNCCF_00348 2.8e-139 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MEGJNCCF_00349 2e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
MEGJNCCF_00350 3.8e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
MEGJNCCF_00351 1.2e-197 1.3.5.4 C FMN_bind
MEGJNCCF_00352 2.2e-56 3.1.3.48 K Transcriptional regulator
MEGJNCCF_00353 3.8e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MEGJNCCF_00354 4.5e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MEGJNCCF_00355 3.7e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MEGJNCCF_00356 9.3e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
MEGJNCCF_00357 1.6e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MEGJNCCF_00358 2.8e-81 S Belongs to the UPF0246 family
MEGJNCCF_00359 5.6e-10 S CAAX protease self-immunity
MEGJNCCF_00360 3.5e-59 ykhA 3.1.2.20 I Thioesterase superfamily
MEGJNCCF_00361 8.7e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MEGJNCCF_00363 1.6e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MEGJNCCF_00364 5.3e-64 C FMN binding
MEGJNCCF_00365 1.3e-204 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MEGJNCCF_00366 1.7e-54 rplI J Binds to the 23S rRNA
MEGJNCCF_00367 3.9e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MEGJNCCF_00368 4.7e-07
MEGJNCCF_00369 1.7e-147 scrR K helix_turn _helix lactose operon repressor
MEGJNCCF_00370 1.8e-217 scrB 3.2.1.26 GH32 G invertase
MEGJNCCF_00371 4e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
MEGJNCCF_00372 2e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MEGJNCCF_00373 2.1e-114 ntpJ P Potassium uptake protein
MEGJNCCF_00374 2.2e-58 ktrA P TrkA-N domain
MEGJNCCF_00375 5.7e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MEGJNCCF_00376 1.1e-43 K helix_turn_helix isocitrate lyase regulation
MEGJNCCF_00377 5.3e-120 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEGJNCCF_00378 1.4e-102 pfoS S Phosphotransferase system, EIIC
MEGJNCCF_00379 1.4e-19
MEGJNCCF_00380 2e-93 S Predicted membrane protein (DUF2207)
MEGJNCCF_00381 1.2e-54 bioY S BioY family
MEGJNCCF_00382 5.7e-184 lmrB EGP Major facilitator Superfamily
MEGJNCCF_00383 2.5e-95 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MEGJNCCF_00384 7.6e-74 glcR K DeoR C terminal sensor domain
MEGJNCCF_00385 1e-60 yceE S haloacid dehalogenase-like hydrolase
MEGJNCCF_00386 1.9e-41 S CAAX protease self-immunity
MEGJNCCF_00387 1.2e-33 S Domain of unknown function (DUF4811)
MEGJNCCF_00388 2.1e-197 lmrB EGP Major facilitator Superfamily
MEGJNCCF_00389 4.2e-32 merR K MerR HTH family regulatory protein
MEGJNCCF_00390 1.8e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEGJNCCF_00391 9.1e-71 S Protein of unknown function (DUF554)
MEGJNCCF_00392 5.3e-120 G Bacterial extracellular solute-binding protein
MEGJNCCF_00393 3e-79 baeR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEGJNCCF_00394 1.6e-100 baeS T Histidine kinase
MEGJNCCF_00395 7e-80 rbsB G sugar-binding domain protein
MEGJNCCF_00396 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MEGJNCCF_00397 6.4e-116 manY G PTS system sorbose-specific iic component
MEGJNCCF_00398 2.1e-147 manN G system, mannose fructose sorbose family IID component
MEGJNCCF_00399 3.2e-52 manO S Domain of unknown function (DUF956)
MEGJNCCF_00400 2.1e-70 mltD CBM50 M NlpC P60 family protein
MEGJNCCF_00401 4.7e-130 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MEGJNCCF_00402 1.6e-163 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEGJNCCF_00403 2.4e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
MEGJNCCF_00404 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MEGJNCCF_00405 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MEGJNCCF_00406 3e-106 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEGJNCCF_00407 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEGJNCCF_00408 2e-46 S CRISPR-associated protein (Cas_Csn2)
MEGJNCCF_00409 7.8e-38 K transcriptional regulator PadR family
MEGJNCCF_00410 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
MEGJNCCF_00411 1.2e-15 S Putative adhesin
MEGJNCCF_00412 2.2e-16 pspC KT PspC domain
MEGJNCCF_00414 5.1e-13 S Enterocin A Immunity
MEGJNCCF_00415 4e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MEGJNCCF_00416 8.2e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
MEGJNCCF_00417 4.3e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MEGJNCCF_00418 1.1e-166 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MEGJNCCF_00419 1.5e-120 potB P ABC transporter permease
MEGJNCCF_00420 4.5e-104 potC U Binding-protein-dependent transport system inner membrane component
MEGJNCCF_00421 1.3e-159 potD P ABC transporter
MEGJNCCF_00422 8.2e-85 ykuT M mechanosensitive ion channel
MEGJNCCF_00424 1e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MEGJNCCF_00425 2e-21 yheA S Belongs to the UPF0342 family
MEGJNCCF_00426 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
MEGJNCCF_00427 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MEGJNCCF_00429 5.4e-53 hit FG histidine triad
MEGJNCCF_00430 2.8e-94 ecsA V ABC transporter, ATP-binding protein
MEGJNCCF_00431 1.3e-72 ecsB U ABC transporter
MEGJNCCF_00432 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
MEGJNCCF_00433 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MEGJNCCF_00434 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MEGJNCCF_00435 6.8e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEGJNCCF_00436 9e-240 sftA D Belongs to the FtsK SpoIIIE SftA family
MEGJNCCF_00437 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MEGJNCCF_00438 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
MEGJNCCF_00439 6.7e-69 ybhL S Belongs to the BI1 family
MEGJNCCF_00440 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MEGJNCCF_00441 8.6e-108 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MEGJNCCF_00442 1.6e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MEGJNCCF_00443 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MEGJNCCF_00444 1.6e-79 dnaB L replication initiation and membrane attachment
MEGJNCCF_00445 2.2e-107 dnaI L Primosomal protein DnaI
MEGJNCCF_00446 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEGJNCCF_00447 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MEGJNCCF_00448 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MEGJNCCF_00449 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MEGJNCCF_00450 2.5e-71 yqeG S HAD phosphatase, family IIIA
MEGJNCCF_00451 7.9e-181 yqeH S Ribosome biogenesis GTPase YqeH
MEGJNCCF_00452 1e-29 yhbY J RNA-binding protein
MEGJNCCF_00453 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MEGJNCCF_00454 7.2e-72 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MEGJNCCF_00455 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MEGJNCCF_00456 4.2e-82 H Nodulation protein S (NodS)
MEGJNCCF_00457 1.3e-122 ylbM S Belongs to the UPF0348 family
MEGJNCCF_00458 2e-57 yceD S Uncharacterized ACR, COG1399
MEGJNCCF_00459 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MEGJNCCF_00460 1.2e-88 plsC 2.3.1.51 I Acyltransferase
MEGJNCCF_00461 1.1e-93 yabB 2.1.1.223 L Methyltransferase small domain
MEGJNCCF_00462 1.5e-27 yazA L GIY-YIG catalytic domain protein
MEGJNCCF_00463 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
MEGJNCCF_00464 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MEGJNCCF_00465 6.9e-37
MEGJNCCF_00466 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MEGJNCCF_00467 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MEGJNCCF_00468 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MEGJNCCF_00469 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MEGJNCCF_00470 2.5e-106 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MEGJNCCF_00472 3.1e-111 K response regulator
MEGJNCCF_00473 5e-167 arlS 2.7.13.3 T Histidine kinase
MEGJNCCF_00475 1.5e-15 yjaB_1 K Acetyltransferase (GNAT) domain
MEGJNCCF_00476 4.3e-09 yjaB_1 K Acetyltransferase (GNAT) domain
MEGJNCCF_00477 3.1e-08
MEGJNCCF_00478 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEGJNCCF_00479 0.0 O Belongs to the peptidase S8 family
MEGJNCCF_00480 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
MEGJNCCF_00481 2.5e-58 tlpA2 L Transposase IS200 like
MEGJNCCF_00482 1.1e-157 L transposase, IS605 OrfB family
MEGJNCCF_00483 4.6e-84 dps P Ferritin-like domain
MEGJNCCF_00484 7.3e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MEGJNCCF_00485 1.6e-43 L hmm pf00665
MEGJNCCF_00486 8.7e-31 tnp L Transposase IS66 family
MEGJNCCF_00487 1.7e-32 P Heavy-metal-associated domain
MEGJNCCF_00488 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MEGJNCCF_00489 1.3e-20 L PFAM transposase IS3 IS911 family protein
MEGJNCCF_00490 1.4e-41 L Integrase core domain
MEGJNCCF_00491 7e-35 L Integrase core domain
MEGJNCCF_00492 2.6e-129 EGP Major Facilitator Superfamily
MEGJNCCF_00493 4.1e-98 EGP Major Facilitator Superfamily
MEGJNCCF_00494 3.7e-72 K Transcriptional regulator, LysR family
MEGJNCCF_00495 4.7e-138 G Xylose isomerase-like TIM barrel
MEGJNCCF_00496 1e-116 IQ Enoyl-(Acyl carrier protein) reductase
MEGJNCCF_00497 1.6e-217 1.3.5.4 C FAD binding domain
MEGJNCCF_00498 2.5e-137 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MEGJNCCF_00499 3.8e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MEGJNCCF_00500 1.4e-142 xerS L Phage integrase family
MEGJNCCF_00504 1.6e-90 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MEGJNCCF_00505 1.4e-70 ptp3 3.1.3.48 T Tyrosine phosphatase family
MEGJNCCF_00506 2.4e-75 desR K helix_turn_helix, Lux Regulon
MEGJNCCF_00507 5.4e-57 salK 2.7.13.3 T Histidine kinase
MEGJNCCF_00508 1.9e-53 yvfS V ABC-2 type transporter
MEGJNCCF_00509 1.5e-78 yvfR V ABC transporter
MEGJNCCF_00512 3.4e-10 S Protein of unknown function (DUF805)
MEGJNCCF_00513 1.8e-08 K transcriptional
MEGJNCCF_00514 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MEGJNCCF_00515 2.3e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MEGJNCCF_00516 1.5e-29
MEGJNCCF_00517 8.2e-16
MEGJNCCF_00518 2.1e-112 rssA S Phospholipase, patatin family
MEGJNCCF_00519 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEGJNCCF_00520 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MEGJNCCF_00521 3.5e-132 ABC-SBP S ABC transporter
MEGJNCCF_00522 3.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MEGJNCCF_00523 6.7e-107 XK27_08845 S ABC transporter, ATP-binding protein
MEGJNCCF_00524 1.1e-65 M ErfK YbiS YcfS YnhG
MEGJNCCF_00525 1.2e-53 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEGJNCCF_00526 4.2e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MEGJNCCF_00527 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MEGJNCCF_00528 1.2e-102 pgm3 G phosphoglycerate mutase
MEGJNCCF_00529 4.7e-56 S CAAX protease self-immunity
MEGJNCCF_00530 2.2e-47 C Flavodoxin
MEGJNCCF_00531 9.7e-60 yphH S Cupin domain
MEGJNCCF_00532 3.6e-46 yphJ 4.1.1.44 S decarboxylase
MEGJNCCF_00533 2.9e-143 E methionine synthase, vitamin-B12 independent
MEGJNCCF_00534 7.4e-107 metQ1 P Belongs to the nlpA lipoprotein family
MEGJNCCF_00535 1.2e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEGJNCCF_00536 2.7e-70 metI P ABC transporter permease
MEGJNCCF_00537 3.3e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MEGJNCCF_00538 3e-84 drgA C nitroreductase
MEGJNCCF_00539 2.5e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
MEGJNCCF_00540 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
MEGJNCCF_00541 8.1e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MEGJNCCF_00542 4.8e-264 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MEGJNCCF_00544 2.3e-150 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEGJNCCF_00545 2.4e-31 metI U ABC transporter permease
MEGJNCCF_00546 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
MEGJNCCF_00547 1.8e-53 S Protein of unknown function (DUF4256)
MEGJNCCF_00550 1e-177 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MEGJNCCF_00551 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
MEGJNCCF_00552 7.6e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEGJNCCF_00553 4e-230 lpdA 1.8.1.4 C Dehydrogenase
MEGJNCCF_00554 2.1e-148 lplA 6.3.1.20 H Lipoate-protein ligase
MEGJNCCF_00555 9.2e-56 S Protein of unknown function (DUF975)
MEGJNCCF_00556 5.7e-78 E GDSL-like Lipase/Acylhydrolase family
MEGJNCCF_00557 1.4e-38
MEGJNCCF_00558 4.1e-27 gcvR T Belongs to the UPF0237 family
MEGJNCCF_00559 2.1e-220 XK27_08635 S UPF0210 protein
MEGJNCCF_00560 4.5e-87 fruR K DeoR C terminal sensor domain
MEGJNCCF_00561 5.3e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MEGJNCCF_00562 4.8e-282 fruA 2.7.1.202 GT Phosphotransferase System
MEGJNCCF_00563 6.2e-171 tonB M YSIRK type signal peptide
MEGJNCCF_00564 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MEGJNCCF_00565 3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
MEGJNCCF_00566 4.7e-163 ytbD EGP Major facilitator Superfamily
MEGJNCCF_00567 4e-110 IQ NAD dependent epimerase/dehydratase family
MEGJNCCF_00568 5.8e-104 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
MEGJNCCF_00569 4.5e-43 gutM K Glucitol operon activator protein (GutM)
MEGJNCCF_00570 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
MEGJNCCF_00571 1.4e-136 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
MEGJNCCF_00572 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MEGJNCCF_00573 9.1e-63 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
MEGJNCCF_00574 5.5e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MEGJNCCF_00575 2.5e-136 pfoS S Phosphotransferase system, EIIC
MEGJNCCF_00577 7.6e-207 spaB S Lantibiotic dehydratase, C terminus
MEGJNCCF_00578 4.3e-184 spaT V ATPases associated with a variety of cellular activities
MEGJNCCF_00579 2.2e-75 spaC2 V Lanthionine synthetase C-like protein
MEGJNCCF_00580 8.8e-90 KT Transcriptional regulatory protein, C terminal
MEGJNCCF_00581 1.7e-105 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MEGJNCCF_00582 1.1e-73 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
MEGJNCCF_00583 9.6e-47 V ABC-2 family transporter protein
MEGJNCCF_00585 2.5e-27 K Helix-turn-helix XRE-family like proteins
MEGJNCCF_00586 7.7e-20 S protein encoded in hypervariable junctions of pilus gene clusters
MEGJNCCF_00588 4.9e-224 E ABC transporter, substratebinding protein
MEGJNCCF_00589 3.6e-116 sufC O FeS assembly ATPase SufC
MEGJNCCF_00590 5.6e-143 sufD O FeS assembly protein SufD
MEGJNCCF_00591 3.3e-148 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MEGJNCCF_00592 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
MEGJNCCF_00593 9.4e-240 sufB O assembly protein SufB
MEGJNCCF_00594 3.3e-45 S VIT family
MEGJNCCF_00595 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
MEGJNCCF_00596 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MEGJNCCF_00597 2.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MEGJNCCF_00598 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEGJNCCF_00599 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEGJNCCF_00600 1.8e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEGJNCCF_00601 4.8e-53 rplQ J Ribosomal protein L17
MEGJNCCF_00602 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEGJNCCF_00603 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MEGJNCCF_00604 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MEGJNCCF_00605 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MEGJNCCF_00606 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MEGJNCCF_00607 3.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MEGJNCCF_00608 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MEGJNCCF_00609 1e-67 rplO J Binds to the 23S rRNA
MEGJNCCF_00610 2.1e-22 rpmD J Ribosomal protein L30
MEGJNCCF_00611 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MEGJNCCF_00612 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MEGJNCCF_00613 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MEGJNCCF_00614 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MEGJNCCF_00615 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEGJNCCF_00616 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MEGJNCCF_00617 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MEGJNCCF_00618 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MEGJNCCF_00619 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MEGJNCCF_00620 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
MEGJNCCF_00621 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MEGJNCCF_00622 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MEGJNCCF_00623 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MEGJNCCF_00624 7.8e-38 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MEGJNCCF_00625 4.1e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MEGJNCCF_00626 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MEGJNCCF_00627 1e-100 rplD J Forms part of the polypeptide exit tunnel
MEGJNCCF_00628 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MEGJNCCF_00629 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MEGJNCCF_00630 4.3e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MEGJNCCF_00631 2.5e-78 K rpiR family
MEGJNCCF_00632 9.1e-45 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MEGJNCCF_00633 3.2e-146 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
MEGJNCCF_00634 6.5e-21 K Acetyltransferase (GNAT) domain
MEGJNCCF_00635 1.8e-148 steT E amino acid
MEGJNCCF_00636 9.6e-78 glnP P ABC transporter permease
MEGJNCCF_00637 1.2e-85 gluC P ABC transporter permease
MEGJNCCF_00638 1.9e-99 glnH ET ABC transporter
MEGJNCCF_00639 3.7e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEGJNCCF_00640 1.3e-09
MEGJNCCF_00641 5e-98
MEGJNCCF_00642 3e-12 3.2.1.14 GH18
MEGJNCCF_00643 5.4e-53 zur P Belongs to the Fur family
MEGJNCCF_00644 6.3e-212 yfnA E Amino Acid
MEGJNCCF_00645 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEGJNCCF_00646 0.0 L Helicase C-terminal domain protein
MEGJNCCF_00647 5e-12 ptp2 3.1.3.48 T Tyrosine phosphatase family
MEGJNCCF_00648 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MEGJNCCF_00649 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEGJNCCF_00650 7.8e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MEGJNCCF_00651 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MEGJNCCF_00652 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MEGJNCCF_00653 1.9e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MEGJNCCF_00654 1.1e-40 yabR J RNA binding
MEGJNCCF_00655 1e-21 divIC D Septum formation initiator
MEGJNCCF_00656 3.6e-31 yabO J S4 domain protein
MEGJNCCF_00657 1.2e-139 yabM S Polysaccharide biosynthesis protein
MEGJNCCF_00658 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MEGJNCCF_00659 2.2e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MEGJNCCF_00660 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MEGJNCCF_00661 2.5e-86 S (CBS) domain
MEGJNCCF_00662 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEGJNCCF_00663 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEGJNCCF_00664 7.2e-53 perR P Belongs to the Fur family
MEGJNCCF_00665 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
MEGJNCCF_00666 7.9e-106 sbcC L Putative exonuclease SbcCD, C subunit
MEGJNCCF_00667 9.8e-115 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MEGJNCCF_00668 6.8e-35 M LysM domain protein
MEGJNCCF_00669 1.1e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MEGJNCCF_00670 1.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MEGJNCCF_00671 1.9e-33 ygfC K transcriptional regulator (TetR family)
MEGJNCCF_00672 2.6e-109 hrtB V ABC transporter permease
MEGJNCCF_00673 4e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MEGJNCCF_00674 0.0 helD 3.6.4.12 L DNA helicase
MEGJNCCF_00675 3.1e-246 yjbQ P TrkA C-terminal domain protein
MEGJNCCF_00676 5.7e-28
MEGJNCCF_00680 3.9e-10
MEGJNCCF_00681 3.8e-99 V domain protein
MEGJNCCF_00682 1.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
MEGJNCCF_00683 1.6e-17
MEGJNCCF_00684 1.1e-104 azlC E AzlC protein
MEGJNCCF_00685 1.3e-38 azlD S branched-chain amino acid
MEGJNCCF_00686 2.4e-65 I alpha/beta hydrolase fold
MEGJNCCF_00687 3.1e-25
MEGJNCCF_00688 1.2e-58 3.6.1.27 I phosphatase
MEGJNCCF_00689 5.4e-23
MEGJNCCF_00690 2.9e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MEGJNCCF_00691 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
MEGJNCCF_00692 3.1e-27 cspC K Cold shock protein
MEGJNCCF_00693 3.6e-81 thrE S Putative threonine/serine exporter
MEGJNCCF_00694 2.8e-49 S Threonine/Serine exporter, ThrE
MEGJNCCF_00695 3.2e-121 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MEGJNCCF_00696 4.9e-87 S Sucrose-6F-phosphate phosphohydrolase
MEGJNCCF_00697 1.9e-34 trxA O Belongs to the thioredoxin family
MEGJNCCF_00698 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEGJNCCF_00699 2e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEGJNCCF_00700 7.3e-65 degV S Uncharacterised protein, DegV family COG1307
MEGJNCCF_00702 4.3e-54 queT S QueT transporter
MEGJNCCF_00703 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
MEGJNCCF_00704 5e-102 IQ Enoyl-(Acyl carrier protein) reductase
MEGJNCCF_00705 4.6e-112 argE 3.5.1.18 E Peptidase dimerisation domain
MEGJNCCF_00706 2.5e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MEGJNCCF_00707 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MEGJNCCF_00708 5e-87 S Alpha beta hydrolase
MEGJNCCF_00709 5.4e-44 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEGJNCCF_00710 3.6e-140 V MatE
MEGJNCCF_00711 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
MEGJNCCF_00712 2.2e-63 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MEGJNCCF_00713 9.6e-97 V ABC transporter
MEGJNCCF_00714 9.6e-132 bacI V MacB-like periplasmic core domain
MEGJNCCF_00715 3.7e-75 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MEGJNCCF_00716 4.8e-26
MEGJNCCF_00717 2.1e-180 yhdP S Transporter associated domain
MEGJNCCF_00718 4.6e-61 S Phage tail protein
MEGJNCCF_00719 4.7e-112 S peptidoglycan catabolic process
MEGJNCCF_00720 6.3e-39 S Bacteriophage Gp15 protein
MEGJNCCF_00722 2e-38 N domain, Protein
MEGJNCCF_00723 7.6e-17 S Minor capsid protein from bacteriophage
MEGJNCCF_00724 1.6e-16 S Minor capsid protein
MEGJNCCF_00725 6.7e-30 S Minor capsid protein
MEGJNCCF_00726 3.4e-14
MEGJNCCF_00727 1.1e-95 S T=7 icosahedral viral capsid
MEGJNCCF_00728 2e-23 S Phage minor structural protein GP20
MEGJNCCF_00730 5.7e-97 S Phage minor capsid protein 2
MEGJNCCF_00731 2.8e-144 S Phage portal protein, SPP1 Gp6-like
MEGJNCCF_00732 7.9e-140 L Phage terminase, large subunit
MEGJNCCF_00733 8.6e-23
MEGJNCCF_00735 2.9e-11 arpU S Phage transcriptional regulator, ArpU family
MEGJNCCF_00739 1.1e-56 Q DNA (cytosine-5-)-methyltransferase activity
MEGJNCCF_00742 2.1e-16
MEGJNCCF_00743 6.7e-45 S magnesium ion binding
MEGJNCCF_00744 0.0 L Primase C terminal 2 (PriCT-2)
MEGJNCCF_00745 5.4e-260 L Helicase C-terminal domain protein
MEGJNCCF_00746 5.6e-82
MEGJNCCF_00747 7.4e-39
MEGJNCCF_00748 1.5e-49
MEGJNCCF_00749 1.5e-101 S AAA domain
MEGJNCCF_00750 3e-155 D AAA domain
MEGJNCCF_00753 1.3e-14 K Cro/C1-type HTH DNA-binding domain
MEGJNCCF_00754 1.2e-19
MEGJNCCF_00757 6.6e-19
MEGJNCCF_00758 6.3e-12 K Cro/C1-type HTH DNA-binding domain
MEGJNCCF_00759 6.4e-43 K addiction module antidote protein HigA
MEGJNCCF_00760 3.6e-37 E IrrE N-terminal-like domain
MEGJNCCF_00761 4.8e-29 S Domain of unknown function (DUF4352)
MEGJNCCF_00762 9.8e-29
MEGJNCCF_00763 4.8e-80 sip L Belongs to the 'phage' integrase family
MEGJNCCF_00764 5.2e-202 hsdM 2.1.1.72 V type I restriction-modification system
MEGJNCCF_00765 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MEGJNCCF_00767 4.9e-22 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
MEGJNCCF_00768 2.8e-56 3.6.1.27 I Acid phosphatase homologues
MEGJNCCF_00769 2.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
MEGJNCCF_00770 4.4e-74 2.3.1.178 M GNAT acetyltransferase
MEGJNCCF_00772 1.2e-196 ade 3.5.4.2 F Adenine deaminase C-terminal domain
MEGJNCCF_00773 1e-64 ypsA S Belongs to the UPF0398 family
MEGJNCCF_00774 4.4e-189 nhaC C Na H antiporter NhaC
MEGJNCCF_00775 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MEGJNCCF_00776 7.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MEGJNCCF_00777 7.3e-113 xerD D recombinase XerD
MEGJNCCF_00778 4.8e-125 cvfB S S1 domain
MEGJNCCF_00779 4.1e-51 yeaL S Protein of unknown function (DUF441)
MEGJNCCF_00780 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MEGJNCCF_00781 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MEGJNCCF_00782 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MEGJNCCF_00783 4.5e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MEGJNCCF_00784 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEGJNCCF_00785 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MEGJNCCF_00786 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MEGJNCCF_00787 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MEGJNCCF_00788 3.9e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MEGJNCCF_00789 1.2e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MEGJNCCF_00790 9.7e-73
MEGJNCCF_00793 4.7e-09 M LysM domain
MEGJNCCF_00794 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MEGJNCCF_00795 1e-27 ysxB J Cysteine protease Prp
MEGJNCCF_00796 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
MEGJNCCF_00799 2.2e-08 S Protein of unknown function (DUF2922)
MEGJNCCF_00801 1.3e-16 K DNA-templated transcription, initiation
MEGJNCCF_00803 1.2e-65 H Methyltransferase domain
MEGJNCCF_00804 3.8e-75 cps2D 5.1.3.2 M RmlD substrate binding domain
MEGJNCCF_00805 2.5e-41 wecD M Acetyltransferase (GNAT) family
MEGJNCCF_00807 1.4e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
MEGJNCCF_00808 4.4e-41 S Protein of unknown function (DUF1211)
MEGJNCCF_00810 5e-86 1.1.1.1 C Zinc-binding dehydrogenase
MEGJNCCF_00811 4.5e-30 S CHY zinc finger
MEGJNCCF_00812 2.1e-39 K Transcriptional regulator
MEGJNCCF_00813 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
MEGJNCCF_00816 5.6e-126 M Glycosyl transferases group 1
MEGJNCCF_00817 7.6e-64 M Glycosyl transferases group 1
MEGJNCCF_00818 3.7e-179 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MEGJNCCF_00819 5.5e-147 lspL 5.1.3.6 GM RmlD substrate binding domain
MEGJNCCF_00820 2.2e-104 cps2I S Psort location CytoplasmicMembrane, score
MEGJNCCF_00821 3.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
MEGJNCCF_00822 2.3e-116 S Glycosyltransferase WbsX
MEGJNCCF_00823 2.7e-52
MEGJNCCF_00825 5.7e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
MEGJNCCF_00826 1e-42 GT2 V Glycosyl transferase, family 2
MEGJNCCF_00827 4.4e-75 M Glycosyltransferase Family 4
MEGJNCCF_00828 1.8e-79 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
MEGJNCCF_00829 5.3e-121 2.4.1.52 GT4 M Glycosyl transferases group 1
MEGJNCCF_00830 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
MEGJNCCF_00831 4.8e-77 epsL M Bacterial sugar transferase
MEGJNCCF_00832 1.2e-45 2.6.1.102 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MEGJNCCF_00833 3.4e-103 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
MEGJNCCF_00834 1.2e-221 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
MEGJNCCF_00835 9.4e-65 cpsD D AAA domain
MEGJNCCF_00836 1.4e-48 cps4C M Chain length determinant protein
MEGJNCCF_00837 6.7e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MEGJNCCF_00838 2e-178 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MEGJNCCF_00839 4.8e-81
MEGJNCCF_00840 1.6e-79 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MEGJNCCF_00841 2.3e-113 yitU 3.1.3.104 S hydrolase
MEGJNCCF_00842 4.5e-60 speG J Acetyltransferase (GNAT) domain
MEGJNCCF_00843 2e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MEGJNCCF_00844 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MEGJNCCF_00845 1.3e-204 pipD E Dipeptidase
MEGJNCCF_00846 2.3e-45
MEGJNCCF_00847 3.5e-64 K helix_turn_helix, arabinose operon control protein
MEGJNCCF_00848 8.9e-54 S Membrane
MEGJNCCF_00849 0.0 rafA 3.2.1.22 G alpha-galactosidase
MEGJNCCF_00850 6.9e-309 L Helicase C-terminal domain protein
MEGJNCCF_00851 1.9e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
MEGJNCCF_00852 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
MEGJNCCF_00853 2.4e-113 2.7.7.65 T diguanylate cyclase activity
MEGJNCCF_00854 0.0 ydaN S Bacterial cellulose synthase subunit
MEGJNCCF_00855 1.2e-201 ydaM M Glycosyl transferase family group 2
MEGJNCCF_00856 5.8e-206 S Protein conserved in bacteria
MEGJNCCF_00857 6.5e-183
MEGJNCCF_00858 1.7e-129 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
MEGJNCCF_00859 2.4e-32 2.7.7.65 T GGDEF domain
MEGJNCCF_00861 1.5e-146 pbuO_1 S Permease family
MEGJNCCF_00862 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
MEGJNCCF_00863 1.5e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MEGJNCCF_00864 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MEGJNCCF_00865 3.6e-220 cydD CO ABC transporter transmembrane region
MEGJNCCF_00866 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MEGJNCCF_00867 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MEGJNCCF_00868 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
MEGJNCCF_00869 6.9e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
MEGJNCCF_00870 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
MEGJNCCF_00871 5e-19 glpE P Rhodanese Homology Domain
MEGJNCCF_00872 1.1e-49 lytE M LysM domain protein
MEGJNCCF_00873 1.4e-92 T Calcineurin-like phosphoesterase superfamily domain
MEGJNCCF_00874 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
MEGJNCCF_00876 4.4e-74 draG O ADP-ribosylglycohydrolase
MEGJNCCF_00877 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEGJNCCF_00878 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MEGJNCCF_00879 8.6e-62 divIVA D DivIVA domain protein
MEGJNCCF_00880 1.7e-81 ylmH S S4 domain protein
MEGJNCCF_00881 3e-19 yggT S YGGT family
MEGJNCCF_00882 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MEGJNCCF_00883 9.8e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEGJNCCF_00884 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MEGJNCCF_00885 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MEGJNCCF_00886 1.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MEGJNCCF_00887 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MEGJNCCF_00888 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MEGJNCCF_00889 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
MEGJNCCF_00890 2.5e-11 ftsL D cell division protein FtsL
MEGJNCCF_00891 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MEGJNCCF_00892 1.5e-55 mraZ K Belongs to the MraZ family
MEGJNCCF_00893 2.9e-07 S Protein of unknown function (DUF3397)
MEGJNCCF_00894 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MEGJNCCF_00896 9.8e-100 D Alpha beta
MEGJNCCF_00897 3.7e-109 aatB ET ABC transporter substrate-binding protein
MEGJNCCF_00898 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEGJNCCF_00899 1.9e-94 glnP P ABC transporter permease
MEGJNCCF_00900 1.8e-126 minD D Belongs to the ParA family
MEGJNCCF_00901 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MEGJNCCF_00902 2e-54 mreD M rod shape-determining protein MreD
MEGJNCCF_00903 2.1e-88 mreC M Involved in formation and maintenance of cell shape
MEGJNCCF_00904 5.1e-155 mreB D cell shape determining protein MreB
MEGJNCCF_00905 4.5e-21 K Cold shock
MEGJNCCF_00906 8.1e-80 radC L DNA repair protein
MEGJNCCF_00907 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MEGJNCCF_00908 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MEGJNCCF_00909 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MEGJNCCF_00910 6.4e-162 iscS2 2.8.1.7 E Aminotransferase class V
MEGJNCCF_00911 5.8e-175 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MEGJNCCF_00912 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
MEGJNCCF_00913 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MEGJNCCF_00914 3.4e-24 yueI S Protein of unknown function (DUF1694)
MEGJNCCF_00915 5.1e-184 rarA L recombination factor protein RarA
MEGJNCCF_00917 6e-72 usp6 T universal stress protein
MEGJNCCF_00918 1.1e-53 tag 3.2.2.20 L glycosylase
MEGJNCCF_00919 7.7e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MEGJNCCF_00920 4.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MEGJNCCF_00922 3.3e-75 yviA S Protein of unknown function (DUF421)
MEGJNCCF_00923 1.8e-27 S Protein of unknown function (DUF3290)
MEGJNCCF_00924 1.5e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
MEGJNCCF_00925 1.2e-296 S membrane
MEGJNCCF_00926 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MEGJNCCF_00927 4e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
MEGJNCCF_00928 6.5e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
MEGJNCCF_00929 2e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MEGJNCCF_00931 1.4e-16
MEGJNCCF_00932 4.8e-199 oatA I Acyltransferase
MEGJNCCF_00933 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MEGJNCCF_00934 1.4e-304 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEGJNCCF_00935 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEGJNCCF_00938 5.1e-42 S Phosphoesterase
MEGJNCCF_00939 2.2e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MEGJNCCF_00940 1.1e-60 yslB S Protein of unknown function (DUF2507)
MEGJNCCF_00941 9.9e-41 trxA O Belongs to the thioredoxin family
MEGJNCCF_00942 3.9e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MEGJNCCF_00943 9.5e-18 cvpA S Colicin V production protein
MEGJNCCF_00944 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MEGJNCCF_00945 1.9e-33 yrzB S Belongs to the UPF0473 family
MEGJNCCF_00946 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MEGJNCCF_00947 2.1e-36 yrzL S Belongs to the UPF0297 family
MEGJNCCF_00948 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MEGJNCCF_00949 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MEGJNCCF_00950 2.7e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MEGJNCCF_00951 7.5e-13
MEGJNCCF_00952 1e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEGJNCCF_00953 1.9e-66 yrjD S LUD domain
MEGJNCCF_00954 2.1e-245 lutB C 4Fe-4S dicluster domain
MEGJNCCF_00955 6.9e-117 lutA C Cysteine-rich domain
MEGJNCCF_00956 2e-208 yfnA E Amino Acid
MEGJNCCF_00958 4.3e-61 uspA T universal stress protein
MEGJNCCF_00960 1.8e-12 yajC U Preprotein translocase
MEGJNCCF_00961 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MEGJNCCF_00962 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MEGJNCCF_00963 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MEGJNCCF_00964 7.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEGJNCCF_00965 6e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MEGJNCCF_00966 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MEGJNCCF_00967 2.2e-181 rny S Endoribonuclease that initiates mRNA decay
MEGJNCCF_00968 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEGJNCCF_00969 1.3e-12 XK27_08315 M Sulfatase
MEGJNCCF_00970 3.2e-129 S Bacterial membrane protein YfhO
MEGJNCCF_00971 8.8e-102 S Bacterial membrane protein, YfhO
MEGJNCCF_00972 8.5e-22 S Bacterial membrane protein, YfhO
MEGJNCCF_00973 2.9e-44 S Bacterial membrane protein, YfhO
MEGJNCCF_00974 3.6e-14
MEGJNCCF_00975 1.2e-45 S Psort location CytoplasmicMembrane, score
MEGJNCCF_00976 3.3e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MEGJNCCF_00977 1.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
MEGJNCCF_00978 2.7e-156 XK27_09615 S reductase
MEGJNCCF_00979 5.4e-67 XK27_09620 S NADPH-dependent FMN reductase
MEGJNCCF_00980 4.7e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MEGJNCCF_00981 2.9e-157 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEGJNCCF_00982 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MEGJNCCF_00983 2.1e-30 gtcA S Teichoic acid glycosylation protein
MEGJNCCF_00984 5e-115 rfbJ M Glycosyl transferase family 2
MEGJNCCF_00985 8.5e-34 S Predicted membrane protein (DUF2142)
MEGJNCCF_00986 3.3e-82
MEGJNCCF_00987 1.7e-210 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MEGJNCCF_00988 1.9e-73 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MEGJNCCF_00989 1e-133 coaA 2.7.1.33 F Pantothenic acid kinase
MEGJNCCF_00990 6.3e-44 E GDSL-like Lipase/Acylhydrolase
MEGJNCCF_00991 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEGJNCCF_00992 1.9e-190 glnPH2 P ABC transporter permease
MEGJNCCF_00993 2.5e-214 yjeM E Amino Acid
MEGJNCCF_00994 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
MEGJNCCF_00995 8.1e-136 tetA EGP Major facilitator Superfamily
MEGJNCCF_00996 8.8e-50 yugI 5.3.1.9 J general stress protein
MEGJNCCF_00997 2.7e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MEGJNCCF_00998 3e-92 dedA S SNARE associated Golgi protein
MEGJNCCF_00999 7.8e-32 S Protein of unknown function (DUF1461)
MEGJNCCF_01000 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MEGJNCCF_01001 1.9e-53 yutD S Protein of unknown function (DUF1027)
MEGJNCCF_01002 3e-57 S Calcineurin-like phosphoesterase
MEGJNCCF_01003 9.3e-184 cycA E Amino acid permease
MEGJNCCF_01004 7.6e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
MEGJNCCF_01006 5.5e-11 S Putative Competence protein ComGF
MEGJNCCF_01008 1.5e-13
MEGJNCCF_01009 1.2e-27 comGC U competence protein ComGC
MEGJNCCF_01010 4.4e-98 comGB NU type II secretion system
MEGJNCCF_01011 4.7e-121 comGA NU Type II IV secretion system protein
MEGJNCCF_01012 2.1e-102 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEGJNCCF_01013 1.5e-119 yebC K Transcriptional regulatory protein
MEGJNCCF_01014 3.7e-42 S VanZ like family
MEGJNCCF_01015 1.3e-158 ccpA K catabolite control protein A
MEGJNCCF_01016 1e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MEGJNCCF_01017 1.5e-13
MEGJNCCF_01020 5.9e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEGJNCCF_01021 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
MEGJNCCF_01022 5.2e-65 hly S protein, hemolysin III
MEGJNCCF_01023 7.3e-41 M1-874 K Domain of unknown function (DUF1836)
MEGJNCCF_01024 9.4e-84 S membrane
MEGJNCCF_01025 1.1e-79 S VIT family
MEGJNCCF_01026 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MEGJNCCF_01027 7.9e-56 P Plays a role in the regulation of phosphate uptake
MEGJNCCF_01028 1.8e-115 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEGJNCCF_01029 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEGJNCCF_01030 3e-122 pstA P Phosphate transport system permease protein PstA
MEGJNCCF_01031 4.6e-118 pstC P probably responsible for the translocation of the substrate across the membrane
MEGJNCCF_01032 3.2e-97 pstS P Phosphate
MEGJNCCF_01033 1.3e-41 yjbH Q Thioredoxin
MEGJNCCF_01034 1.9e-232 pepF E oligoendopeptidase F
MEGJNCCF_01035 1.1e-68 coiA 3.6.4.12 S Competence protein
MEGJNCCF_01036 2.1e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MEGJNCCF_01037 5.1e-42 wecD K Acetyltransferase GNAT Family
MEGJNCCF_01038 3.9e-47 hmpT S ECF-type riboflavin transporter, S component
MEGJNCCF_01039 2.1e-69 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MEGJNCCF_01040 1.7e-09 yvaZ S Protein of unknown function (DUF1648)
MEGJNCCF_01041 1.7e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
MEGJNCCF_01042 3.4e-285 pepO 3.4.24.71 O Peptidase family M13
MEGJNCCF_01043 7.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
MEGJNCCF_01044 6.9e-54 K Transcriptional regulator C-terminal region
MEGJNCCF_01045 1.6e-55 jag S R3H domain protein
MEGJNCCF_01046 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
MEGJNCCF_01047 2e-31 azlD S Branched-chain amino acid transport protein (AzlD)
MEGJNCCF_01048 2e-76 azlC E branched-chain amino acid
MEGJNCCF_01049 5.5e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
MEGJNCCF_01050 9.4e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MEGJNCCF_01051 4.7e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
MEGJNCCF_01052 3.8e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
MEGJNCCF_01053 1.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
MEGJNCCF_01054 4.1e-75 XK27_02070 S Nitroreductase family
MEGJNCCF_01055 1.7e-111 endA F DNA RNA non-specific endonuclease
MEGJNCCF_01057 5.9e-210 brnQ U Component of the transport system for branched-chain amino acids
MEGJNCCF_01058 6.5e-61 K Bacterial regulatory proteins, tetR family
MEGJNCCF_01059 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MEGJNCCF_01060 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MEGJNCCF_01061 9.5e-69 dhaL 2.7.1.121 S Dak2
MEGJNCCF_01062 4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
MEGJNCCF_01063 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MEGJNCCF_01064 9.8e-177 yjcE P Sodium proton antiporter
MEGJNCCF_01065 4e-210 mtlR K Mga helix-turn-helix domain
MEGJNCCF_01066 5.9e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEGJNCCF_01067 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MEGJNCCF_01068 1.9e-243 lysP E amino acid
MEGJNCCF_01069 2.3e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
MEGJNCCF_01070 1.2e-265 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MEGJNCCF_01072 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MEGJNCCF_01073 7.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
MEGJNCCF_01074 1.7e-82 lysR5 K LysR substrate binding domain
MEGJNCCF_01075 6.5e-119 yxaA S membrane transporter protein
MEGJNCCF_01076 2.6e-32 ywjH S Protein of unknown function (DUF1634)
MEGJNCCF_01077 4.1e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MEGJNCCF_01078 5.1e-225 pipD E Dipeptidase
MEGJNCCF_01079 2.3e-21 K helix_turn_helix multiple antibiotic resistance protein
MEGJNCCF_01080 8.8e-166 EGP Major facilitator Superfamily
MEGJNCCF_01081 5.6e-82 S L,D-transpeptidase catalytic domain
MEGJNCCF_01082 3.5e-141 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MEGJNCCF_01083 2.2e-143 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MEGJNCCF_01084 7.2e-27 ydiI Q Thioesterase superfamily
MEGJNCCF_01085 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
MEGJNCCF_01086 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MEGJNCCF_01087 6.4e-114 degV S EDD domain protein, DegV family
MEGJNCCF_01088 1e-225 cadA P P-type ATPase
MEGJNCCF_01089 1.8e-254 E Amino acid permease
MEGJNCCF_01090 3.9e-82 S Membrane
MEGJNCCF_01091 9.1e-50 cps3F
MEGJNCCF_01092 1.2e-145 Q Imidazolonepropionase and related amidohydrolases
MEGJNCCF_01093 1e-149 E glutamate:sodium symporter activity
MEGJNCCF_01094 1.2e-143 dapE 3.5.1.18 E Peptidase dimerisation domain
MEGJNCCF_01095 5.4e-48 3.1.21.3 V Type I restriction modification DNA specificity domain
MEGJNCCF_01096 3.2e-37 hsdM 2.1.1.72 V type I restriction-modification system
MEGJNCCF_01097 1.3e-162 hsdM 2.1.1.72 V cog cog0286
MEGJNCCF_01098 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MEGJNCCF_01099 5.4e-19 K Cro/C1-type HTH DNA-binding domain
MEGJNCCF_01100 9.1e-78 L AAA domain
MEGJNCCF_01101 4.1e-16
MEGJNCCF_01102 3e-22
MEGJNCCF_01103 1.3e-75 K phage regulatory protein, rha family
MEGJNCCF_01104 1.3e-17
MEGJNCCF_01105 1.4e-121 L Mrr N-terminal domain
MEGJNCCF_01106 1.1e-208 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEGJNCCF_01107 6.4e-145 yegS 2.7.1.107 G Lipid kinase
MEGJNCCF_01108 2.8e-255 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEGJNCCF_01109 4e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MEGJNCCF_01110 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEGJNCCF_01111 9.3e-161 camS S sex pheromone
MEGJNCCF_01112 1.3e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEGJNCCF_01113 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MEGJNCCF_01114 4.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MEGJNCCF_01116 5.7e-24
MEGJNCCF_01119 2.8e-167 potE2 E amino acid
MEGJNCCF_01120 2.1e-146 ald 1.4.1.1 C Belongs to the AlaDH PNT family
MEGJNCCF_01121 6.7e-115 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MEGJNCCF_01122 2.8e-56 racA K Domain of unknown function (DUF1836)
MEGJNCCF_01123 3.8e-79 yitS S EDD domain protein, DegV family
MEGJNCCF_01125 6.6e-60 uspA T Universal stress protein family
MEGJNCCF_01126 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
MEGJNCCF_01127 1.1e-25
MEGJNCCF_01128 2.2e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MEGJNCCF_01129 8e-110 puuD S peptidase C26
MEGJNCCF_01130 5.2e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEGJNCCF_01131 4.3e-150 lsa S ABC transporter
MEGJNCCF_01132 1.1e-43 mepA V MATE efflux family protein
MEGJNCCF_01133 1.2e-96 mepA V MATE efflux family protein
MEGJNCCF_01134 4.9e-217 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEGJNCCF_01135 2.1e-71 L PFAM transposase IS200-family protein
MEGJNCCF_01136 2.2e-60 L HTH-like domain
MEGJNCCF_01137 5.9e-30 L Helix-turn-helix domain
MEGJNCCF_01138 1.1e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
MEGJNCCF_01139 1.8e-270 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEGJNCCF_01140 4e-101 pncA Q Isochorismatase family
MEGJNCCF_01141 1e-25 tnpR L Resolvase, N terminal domain
MEGJNCCF_01142 1e-99 K Bacterial regulatory proteins, tetR family
MEGJNCCF_01143 3.3e-293 norB EGP Major Facilitator
MEGJNCCF_01145 4e-44
MEGJNCCF_01146 1e-39 S RelB antitoxin
MEGJNCCF_01147 9.6e-107
MEGJNCCF_01148 4.7e-100 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MEGJNCCF_01149 1.1e-95 3.1.1.85 S Serine hydrolase
MEGJNCCF_01150 6.4e-24
MEGJNCCF_01151 1.9e-310 M Cna protein B-type domain
MEGJNCCF_01152 4e-97 M Cna protein B-type domain
MEGJNCCF_01153 1.1e-258 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MEGJNCCF_01154 4.6e-79
MEGJNCCF_01155 1.1e-47 L Transposase
MEGJNCCF_01156 2.5e-158 L Transposase
MEGJNCCF_01157 6.3e-11 S Protein of unknown function (DUF3021)
MEGJNCCF_01158 7e-27 K LytTr DNA-binding domain
MEGJNCCF_01159 4.1e-60 cylB V ABC-2 type transporter
MEGJNCCF_01160 2.4e-76 cylA V abc transporter atp-binding protein
MEGJNCCF_01162 3e-36
MEGJNCCF_01163 1.3e-65 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEGJNCCF_01164 4.2e-61 marR K Transcriptional regulator, MarR family
MEGJNCCF_01165 6.4e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEGJNCCF_01166 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEGJNCCF_01167 6.5e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MEGJNCCF_01168 1.4e-98 IQ reductase
MEGJNCCF_01169 6.9e-194 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEGJNCCF_01170 7.9e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MEGJNCCF_01171 1.5e-63 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEGJNCCF_01172 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MEGJNCCF_01173 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MEGJNCCF_01174 5.7e-101 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MEGJNCCF_01175 8.3e-14 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MEGJNCCF_01176 1.4e-86 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MEGJNCCF_01177 1.5e-230 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MEGJNCCF_01178 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
MEGJNCCF_01179 2.7e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEGJNCCF_01180 5.7e-119 gla U Major intrinsic protein
MEGJNCCF_01181 5.8e-45 ykuL S CBS domain
MEGJNCCF_01182 1.5e-60 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MEGJNCCF_01183 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MEGJNCCF_01184 8.2e-68 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEGJNCCF_01185 9.9e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
MEGJNCCF_01186 8e-72 K Transcriptional regulator
MEGJNCCF_01187 1.1e-124 akr5f 1.1.1.346 S reductase
MEGJNCCF_01188 3.3e-117 EGP Major Facilitator Superfamily
MEGJNCCF_01189 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MEGJNCCF_01190 8.1e-280 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MEGJNCCF_01191 1.3e-212 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MEGJNCCF_01192 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MEGJNCCF_01194 4.7e-91 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEGJNCCF_01195 4.8e-44
MEGJNCCF_01196 7.1e-120 ica2 GT2 M Glycosyl transferase family group 2
MEGJNCCF_01197 2.9e-35 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
MEGJNCCF_01201 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MEGJNCCF_01202 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEGJNCCF_01203 9.7e-194 cycA E Amino acid permease
MEGJNCCF_01204 8.3e-187 ytgP S Polysaccharide biosynthesis protein
MEGJNCCF_01205 1.1e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MEGJNCCF_01206 1.2e-80 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MEGJNCCF_01207 5.1e-193 pepV 3.5.1.18 E dipeptidase PepV
MEGJNCCF_01208 3.3e-182 S Protein of unknown function DUF262
MEGJNCCF_01209 6.1e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MEGJNCCF_01210 3.2e-29 ponA V the current gene model (or a revised gene model) may contain a frame shift
MEGJNCCF_01212 4.5e-102 tcyB E ABC transporter
MEGJNCCF_01213 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEGJNCCF_01214 2.6e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MEGJNCCF_01215 1.6e-38 K Transcriptional regulator
MEGJNCCF_01216 2.2e-107 terC P Integral membrane protein TerC family
MEGJNCCF_01217 4.2e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
MEGJNCCF_01218 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEGJNCCF_01219 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
MEGJNCCF_01220 6.9e-41 gntR1 K Transcriptional regulator, GntR family
MEGJNCCF_01221 8e-96 V ABC transporter, ATP-binding protein
MEGJNCCF_01222 2.5e-08
MEGJNCCF_01223 1.1e-39 ybjQ S Belongs to the UPF0145 family
MEGJNCCF_01224 4.7e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
MEGJNCCF_01225 1.5e-96 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEGJNCCF_01226 1e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MEGJNCCF_01227 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEGJNCCF_01228 1.1e-33
MEGJNCCF_01229 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MEGJNCCF_01230 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MEGJNCCF_01231 2.3e-63 srtA 3.4.22.70 M sortase family
MEGJNCCF_01233 1.8e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MEGJNCCF_01234 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
MEGJNCCF_01235 0.0 pacL 3.6.3.8 P P-type ATPase
MEGJNCCF_01236 2.4e-109 3.1.4.46 C phosphodiesterase
MEGJNCCF_01237 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MEGJNCCF_01238 4e-101 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MEGJNCCF_01239 1.4e-81 noc K Belongs to the ParB family
MEGJNCCF_01240 6.5e-118 soj D Sporulation initiation inhibitor
MEGJNCCF_01241 1.8e-108 spo0J K Belongs to the ParB family
MEGJNCCF_01242 3.4e-23 yyzM S Bacterial protein of unknown function (DUF951)
MEGJNCCF_01243 5.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MEGJNCCF_01244 6.5e-54 XK27_01040 S Protein of unknown function (DUF1129)
MEGJNCCF_01245 7.6e-38
MEGJNCCF_01246 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
MEGJNCCF_01247 1e-98 fhuC P ABC transporter
MEGJNCCF_01248 2.5e-96 znuB U ABC 3 transport family
MEGJNCCF_01249 1.5e-55 S ECF transporter, substrate-specific component
MEGJNCCF_01250 1e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MEGJNCCF_01251 9.8e-90 S NADPH-dependent FMN reductase
MEGJNCCF_01252 1.2e-27 yraB K transcriptional regulator
MEGJNCCF_01253 5.3e-68 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MEGJNCCF_01255 2.9e-153 EGP Major facilitator Superfamily
MEGJNCCF_01256 2.3e-58 S Haloacid dehalogenase-like hydrolase
MEGJNCCF_01257 9.1e-89 yvyE 3.4.13.9 S YigZ family
MEGJNCCF_01258 3e-39 S CAAX protease self-immunity
MEGJNCCF_01259 2.6e-117 cps1D M Domain of unknown function (DUF4422)
MEGJNCCF_01260 2.5e-61 S Glycosyltransferase like family 2
MEGJNCCF_01261 1.3e-75 S Glycosyltransferase like family 2
MEGJNCCF_01262 1.2e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MEGJNCCF_01263 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MEGJNCCF_01264 6.2e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEGJNCCF_01265 9.9e-128 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MEGJNCCF_01266 9.4e-118 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
MEGJNCCF_01267 9.8e-27 S zinc-ribbon domain
MEGJNCCF_01268 2e-80 S response to antibiotic
MEGJNCCF_01270 9.7e-174 rgpAc GT4 M Domain of unknown function (DUF1972)
MEGJNCCF_01271 1.9e-120 G Glycosyltransferase Family 4
MEGJNCCF_01272 6.8e-47 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
MEGJNCCF_01273 3.6e-143 M Glycosyl transferase family 2
MEGJNCCF_01274 7.3e-46 S Glycosyl transferase family 2
MEGJNCCF_01276 1.3e-42 M Glycosyltransferase like family 2
MEGJNCCF_01277 5.8e-26 S Acetyltransferase (Isoleucine patch superfamily)
MEGJNCCF_01278 6.3e-130 S Membrane protein involved in the export of O-antigen and teichoic acid
MEGJNCCF_01279 3e-41 S Acyltransferase family
MEGJNCCF_01280 1e-42
MEGJNCCF_01281 3.2e-214 ugd 1.1.1.22 M UDP binding domain
MEGJNCCF_01282 3.4e-77 epsB M biosynthesis protein
MEGJNCCF_01283 5e-77 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MEGJNCCF_01284 1.9e-140 XK27_08315 M Sulfatase
MEGJNCCF_01285 4.6e-09 ganB 3.2.1.89 G arabinogalactan
MEGJNCCF_01286 1.5e-39 ywqE 3.1.3.48 GM PHP domain protein
MEGJNCCF_01287 1.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MEGJNCCF_01288 2e-91 rfbP M Bacterial sugar transferase
MEGJNCCF_01289 1.8e-95 M Core-2/I-Branching enzyme
MEGJNCCF_01290 1.6e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
MEGJNCCF_01291 3.7e-65 S Glycosyltransferase like family 2
MEGJNCCF_01292 2e-160 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
MEGJNCCF_01293 5.8e-57 cps3F
MEGJNCCF_01294 9.8e-74 M transferase activity, transferring glycosyl groups
MEGJNCCF_01295 1.1e-06 3.5.1.28 M Putative cell wall binding repeat
MEGJNCCF_01296 3.6e-82 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEGJNCCF_01297 4.1e-177 thrC 4.2.3.1 E Threonine synthase
MEGJNCCF_01298 2.4e-128 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MEGJNCCF_01299 5.2e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MEGJNCCF_01300 5.6e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MEGJNCCF_01301 6.8e-57 S peptidoglycan catabolic process
MEGJNCCF_01302 1.5e-194 XK27_08315 M Sulfatase
MEGJNCCF_01304 6.4e-168 mdtG EGP Major facilitator Superfamily
MEGJNCCF_01305 6.3e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MEGJNCCF_01306 5.7e-84 treR K UTRA
MEGJNCCF_01307 3.3e-259 treB G phosphotransferase system
MEGJNCCF_01308 3.5e-63 3.1.3.73 G phosphoglycerate mutase
MEGJNCCF_01309 2.4e-82 pncA Q isochorismatase
MEGJNCCF_01310 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MEGJNCCF_01311 1.2e-103 ydhQ K UbiC transcription regulator-associated domain protein
MEGJNCCF_01312 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MEGJNCCF_01313 3.6e-41 K Transcriptional regulator, HxlR family
MEGJNCCF_01314 8.3e-164 C Luciferase-like monooxygenase
MEGJNCCF_01315 2.2e-184 L Probable transposase
MEGJNCCF_01316 9.1e-67 1.5.1.38 S NADPH-dependent FMN reductase
MEGJNCCF_01317 5.8e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MEGJNCCF_01318 3.9e-76 L haloacid dehalogenase-like hydrolase
MEGJNCCF_01319 4e-61 EG EamA-like transporter family
MEGJNCCF_01320 5.3e-118 K AI-2E family transporter
MEGJNCCF_01321 1.3e-173 malY 4.4.1.8 E Aminotransferase, class I
MEGJNCCF_01322 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEGJNCCF_01323 6.2e-43 S virion core protein, lumpy skin disease virus
MEGJNCCF_01324 0.0 L MobA MobL family protein
MEGJNCCF_01325 2.8e-23
MEGJNCCF_01326 4e-41
MEGJNCCF_01327 2.7e-123 S protein conserved in bacteria
MEGJNCCF_01328 3.2e-26
MEGJNCCF_01329 4.8e-42 relB L Addiction module antitoxin, RelB DinJ family
MEGJNCCF_01330 1.1e-138 S Fic/DOC family
MEGJNCCF_01331 4.9e-25
MEGJNCCF_01332 2e-147 repA S Replication initiator protein A
MEGJNCCF_01333 8.5e-35
MEGJNCCF_01334 4.9e-148 D CobQ CobB MinD ParA nucleotide binding domain protein
MEGJNCCF_01335 2.6e-55 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
MEGJNCCF_01336 1.2e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MEGJNCCF_01337 6.4e-96 XK27_06785 V ABC transporter, ATP-binding protein
MEGJNCCF_01338 1.2e-253 XK27_06780 V ABC transporter permease
MEGJNCCF_01339 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MEGJNCCF_01340 2.5e-211 glnP P ABC transporter
MEGJNCCF_01344 8.1e-09 hol S Bacteriophage holin
MEGJNCCF_01345 6.5e-131 M Glycosyl hydrolases family 25
MEGJNCCF_01349 8.1e-15 S Bacteriophage holin family
MEGJNCCF_01350 2.5e-119 S N-acetylmuramoyl-L-alanine amidase activity
MEGJNCCF_01351 9.1e-76 3.1.21.3 V Type I restriction modification DNA specificity domain
MEGJNCCF_01352 1.6e-131 L Belongs to the 'phage' integrase family
MEGJNCCF_01353 1.2e-36 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MEGJNCCF_01355 6.9e-07 N Bacterial Ig-like domain 2
MEGJNCCF_01357 7e-218 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
MEGJNCCF_01358 1.2e-45 V HNH endonuclease
MEGJNCCF_01360 8.1e-68 rny D Peptidase family M23
MEGJNCCF_01362 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEGJNCCF_01363 2.9e-64 ymfM S Helix-turn-helix domain
MEGJNCCF_01364 8.4e-91 IQ Enoyl-(Acyl carrier protein) reductase
MEGJNCCF_01365 1.3e-147 ymfH S Peptidase M16
MEGJNCCF_01366 4.5e-108 ymfF S Peptidase M16 inactive domain protein
MEGJNCCF_01367 2e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
MEGJNCCF_01368 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MEGJNCCF_01369 1.7e-98 rrmA 2.1.1.187 H Methyltransferase
MEGJNCCF_01370 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
MEGJNCCF_01371 5e-163 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEGJNCCF_01372 4e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEGJNCCF_01373 3.2e-21 cutC P Participates in the control of copper homeostasis
MEGJNCCF_01374 5.3e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MEGJNCCF_01375 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MEGJNCCF_01376 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MEGJNCCF_01377 5.3e-68 ybbR S YbbR-like protein
MEGJNCCF_01378 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MEGJNCCF_01379 2.4e-71 S Protein of unknown function (DUF1361)
MEGJNCCF_01380 3.5e-115 murB 1.3.1.98 M Cell wall formation
MEGJNCCF_01381 1.9e-68 dnaQ 2.7.7.7 L DNA polymerase III
MEGJNCCF_01382 3.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MEGJNCCF_01383 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MEGJNCCF_01384 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MEGJNCCF_01385 2.4e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
MEGJNCCF_01386 9.1e-42 yxjI
MEGJNCCF_01387 4.5e-69 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MEGJNCCF_01388 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MEGJNCCF_01389 2.8e-19 secG U Preprotein translocase
MEGJNCCF_01390 1.2e-179 clcA P chloride
MEGJNCCF_01391 6.7e-146 lmrP E Major Facilitator Superfamily
MEGJNCCF_01392 1.8e-169 T PhoQ Sensor
MEGJNCCF_01393 5e-104 K response regulator
MEGJNCCF_01394 3.2e-131 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEGJNCCF_01395 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEGJNCCF_01396 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEGJNCCF_01397 1.6e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MEGJNCCF_01398 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEGJNCCF_01399 1.1e-136 cggR K Putative sugar-binding domain
MEGJNCCF_01401 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEGJNCCF_01402 1.8e-149 whiA K May be required for sporulation
MEGJNCCF_01403 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MEGJNCCF_01404 7.5e-126 rapZ S Displays ATPase and GTPase activities
MEGJNCCF_01405 5e-79 ylbE GM NAD dependent epimerase dehydratase family protein
MEGJNCCF_01406 2.4e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MEGJNCCF_01407 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MEGJNCCF_01408 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MEGJNCCF_01409 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MEGJNCCF_01410 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MEGJNCCF_01411 8.7e-133 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MEGJNCCF_01412 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MEGJNCCF_01413 2.4e-08 pspC KT PspC domain
MEGJNCCF_01414 1.2e-85 phoR 2.7.13.3 T Histidine kinase
MEGJNCCF_01415 6e-86 K response regulator
MEGJNCCF_01416 9.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
MEGJNCCF_01417 2.2e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MEGJNCCF_01418 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEGJNCCF_01419 7e-95 yeaN P Major Facilitator Superfamily
MEGJNCCF_01420 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MEGJNCCF_01421 5.6e-44 comFC S Competence protein
MEGJNCCF_01422 3.2e-128 comFA L Helicase C-terminal domain protein
MEGJNCCF_01423 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
MEGJNCCF_01424 1.2e-295 ydaO E amino acid
MEGJNCCF_01425 2.5e-269 aha1 P COG COG0474 Cation transport ATPase
MEGJNCCF_01426 1.3e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MEGJNCCF_01427 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MEGJNCCF_01428 1.4e-33 S CAAX protease self-immunity
MEGJNCCF_01429 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MEGJNCCF_01430 6.9e-257 uup S ABC transporter, ATP-binding protein
MEGJNCCF_01431 8.4e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MEGJNCCF_01432 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MEGJNCCF_01433 3.7e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MEGJNCCF_01434 3.5e-140 ansA 3.5.1.1 EJ Asparaginase
MEGJNCCF_01435 4.7e-81 fat 3.1.2.21 I Acyl-ACP thioesterase
MEGJNCCF_01436 4.1e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MEGJNCCF_01437 1.4e-40 yabA L Involved in initiation control of chromosome replication
MEGJNCCF_01438 3.9e-83 holB 2.7.7.7 L DNA polymerase III
MEGJNCCF_01439 1.4e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MEGJNCCF_01440 9.2e-29 yaaL S Protein of unknown function (DUF2508)
MEGJNCCF_01441 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MEGJNCCF_01442 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MEGJNCCF_01443 4.3e-210 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEGJNCCF_01444 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MEGJNCCF_01445 1.1e-75 rsmC 2.1.1.172 J Methyltransferase
MEGJNCCF_01446 1.2e-27 nrdH O Glutaredoxin
MEGJNCCF_01447 4.8e-45 nrdI F NrdI Flavodoxin like
MEGJNCCF_01448 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEGJNCCF_01449 8.8e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEGJNCCF_01450 1.6e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEGJNCCF_01451 1.4e-54
MEGJNCCF_01452 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MEGJNCCF_01453 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MEGJNCCF_01454 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MEGJNCCF_01455 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MEGJNCCF_01456 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
MEGJNCCF_01457 9.9e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MEGJNCCF_01458 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MEGJNCCF_01459 5.4e-71 yacP S YacP-like NYN domain
MEGJNCCF_01460 3.2e-109 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEGJNCCF_01461 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MEGJNCCF_01462 1.8e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEGJNCCF_01463 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEGJNCCF_01464 8.2e-154 yacL S domain protein
MEGJNCCF_01465 5.4e-224 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MEGJNCCF_01466 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MEGJNCCF_01467 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
MEGJNCCF_01468 7.6e-223 pepC 3.4.22.40 E Peptidase C1-like family
MEGJNCCF_01469 1e-33 S Enterocin A Immunity
MEGJNCCF_01470 4.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEGJNCCF_01471 5.9e-129 mleP2 S Sodium Bile acid symporter family
MEGJNCCF_01472 1.3e-115 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEGJNCCF_01474 7.2e-45 ydcK S Belongs to the SprT family
MEGJNCCF_01475 8.2e-251 yhgF K Tex-like protein N-terminal domain protein
MEGJNCCF_01476 3.6e-130 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MEGJNCCF_01477 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEGJNCCF_01478 2.5e-90 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MEGJNCCF_01479 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
MEGJNCCF_01480 5.9e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEGJNCCF_01482 1.1e-07
MEGJNCCF_01483 1.6e-197 dtpT U amino acid peptide transporter
MEGJNCCF_01487 4e-07
MEGJNCCF_01488 2.1e-07
MEGJNCCF_01491 3e-16
MEGJNCCF_01492 1.5e-08
MEGJNCCF_01493 1.3e-37
MEGJNCCF_01494 8.4e-50
MEGJNCCF_01495 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
MEGJNCCF_01496 4.4e-307 S TIGR02687 family
MEGJNCCF_01497 0.0 V restriction
MEGJNCCF_01498 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
MEGJNCCF_01499 6.9e-69 S Domain of unknown function (DUF1788)
MEGJNCCF_01500 2.6e-80 S Putative inner membrane protein (DUF1819)
MEGJNCCF_01501 4.3e-26 K Cro/C1-type HTH DNA-binding domain
MEGJNCCF_01502 1.9e-59 hsdM 2.1.1.72 V type I restriction-modification system
MEGJNCCF_01503 5.7e-23 3.1.21.3 V Type I restriction modification DNA specificity domain
MEGJNCCF_01504 7.6e-105 L Belongs to the 'phage' integrase family
MEGJNCCF_01505 1.7e-19 S YjcQ protein
MEGJNCCF_01507 1.5e-109 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
MEGJNCCF_01508 2.2e-219 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
MEGJNCCF_01509 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MEGJNCCF_01510 4.1e-214 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MEGJNCCF_01511 1.5e-188 iolF EGP Major facilitator Superfamily
MEGJNCCF_01512 4.8e-76 rhaR K helix_turn_helix, arabinose operon control protein
MEGJNCCF_01513 1.9e-49 S Membrane
MEGJNCCF_01514 6.1e-181 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
MEGJNCCF_01515 2.3e-57 yvbG U MarC family integral membrane protein
MEGJNCCF_01516 2.9e-16 2.7.1.194, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
MEGJNCCF_01517 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
MEGJNCCF_01518 1.4e-148 yedE S Sulphur transport
MEGJNCCF_01519 2.7e-100 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
MEGJNCCF_01520 3.4e-175 rnfC C RnfC Barrel sandwich hybrid domain
MEGJNCCF_01521 6.9e-29 yitW S Iron-sulfur cluster assembly protein
MEGJNCCF_01522 9.1e-110 selA 2.9.1.1 J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
MEGJNCCF_01523 8.8e-111 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
MEGJNCCF_01524 1.4e-137 selB J Elongation factor SelB, winged helix
MEGJNCCF_01525 2.9e-07 S Protein of unknown function (DUF3343)
MEGJNCCF_01526 1.2e-48 yedF O Belongs to the sulfur carrier protein TusA family
MEGJNCCF_01527 4.1e-223 ybeC E amino acid
MEGJNCCF_01528 2.2e-93 XK27_00825 S Sulfite exporter TauE/SafE
MEGJNCCF_01529 7.8e-143 5.1.1.4 E Proline racemase
MEGJNCCF_01530 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
MEGJNCCF_01531 6.8e-72 prdD S An automated process has identified a potential problem with this gene model
MEGJNCCF_01532 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
MEGJNCCF_01533 4.5e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
MEGJNCCF_01534 2.1e-25 S Psort location Cytoplasmic, score
MEGJNCCF_01535 3.6e-234 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
MEGJNCCF_01537 1.5e-115 ynjE 2.8.1.11 P Rhodanese Homology Domain
MEGJNCCF_01538 5.4e-17 yeeD O Belongs to the sulfur carrier protein TusA family
MEGJNCCF_01539 3.1e-62 yeeE S Sulphur transport
MEGJNCCF_01540 8.8e-105 yraQ S Predicted permease
MEGJNCCF_01541 1.6e-125 yvgN C Aldo keto reductase
MEGJNCCF_01542 5e-108 XK27_09655 S Virulence protein RhuM family
MEGJNCCF_01543 4.2e-21 M domain protein
MEGJNCCF_01544 3e-35 agrA KT Response regulator of the LytR AlgR family
MEGJNCCF_01545 1e-43 2.7.13.3 T protein histidine kinase activity
MEGJNCCF_01546 0.0 pepN 3.4.11.2 E aminopeptidase
MEGJNCCF_01547 6.4e-36
MEGJNCCF_01549 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
MEGJNCCF_01550 6e-17 bglG K antiterminator
MEGJNCCF_01551 8.4e-91 2.7.1.193, 2.7.1.199, 2.7.1.208, 2.7.1.211 G .Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome down-regulated in Spo0A mutant
MEGJNCCF_01552 1.6e-37 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MEGJNCCF_01553 1.8e-85 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MEGJNCCF_01554 3.9e-38 S Replication initiator protein A (RepA) N-terminus
MEGJNCCF_01555 9.4e-109 L Initiator Replication protein
MEGJNCCF_01556 2.3e-07 G SMI1 / KNR4 family (SUKH-1)
MEGJNCCF_01558 3e-39 L PLD-like domain
MEGJNCCF_01559 1.4e-134 L PLD-like domain
MEGJNCCF_01560 6.5e-79 S Fic/DOC family
MEGJNCCF_01561 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MEGJNCCF_01562 2.2e-60 K DeoR C terminal sensor domain
MEGJNCCF_01563 2.1e-39 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEGJNCCF_01564 2e-35 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MEGJNCCF_01565 2.4e-181 gatC G PTS system sugar-specific permease component
MEGJNCCF_01566 1.2e-119 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
MEGJNCCF_01567 5.3e-166 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
MEGJNCCF_01568 2.3e-87 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MEGJNCCF_01569 5.2e-276 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MEGJNCCF_01570 5.3e-233 tetP J elongation factor G
MEGJNCCF_01571 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEGJNCCF_01573 1.5e-216 yjeM E Amino Acid
MEGJNCCF_01574 2.1e-58 yphA GM NAD dependent epimerase/dehydratase family
MEGJNCCF_01575 4.3e-75 K Helix-turn-helix domain, rpiR family
MEGJNCCF_01576 3.3e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MEGJNCCF_01577 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MEGJNCCF_01578 6.5e-90 nanK GK ROK family
MEGJNCCF_01579 1.9e-53 ndk 2.7.4.6 F Belongs to the NDK family
MEGJNCCF_01580 6.1e-65 G Xylose isomerase domain protein TIM barrel
MEGJNCCF_01581 7.9e-155 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEGJNCCF_01582 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEGJNCCF_01583 1.8e-62 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MEGJNCCF_01584 1.4e-111 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MEGJNCCF_01585 7.7e-41 S Iron-sulfur cluster assembly protein
MEGJNCCF_01586 1.3e-66 S Protein of unknown function (DUF1440)
MEGJNCCF_01587 1.7e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MEGJNCCF_01588 5.9e-187 mtnE 2.6.1.83 E Aminotransferase
MEGJNCCF_01590 2.7e-15
MEGJNCCF_01591 1e-87 S Haloacid dehalogenase-like hydrolase
MEGJNCCF_01594 6.4e-71 xerD L Phage integrase, N-terminal SAM-like domain
MEGJNCCF_01595 3.1e-265 fbp 3.1.3.11 G phosphatase activity
MEGJNCCF_01598 1.8e-99 M Prophage endopeptidase tail
MEGJNCCF_01599 1.6e-274 rny D peptidase
MEGJNCCF_01600 6.8e-129 S Phage tail protein
MEGJNCCF_01601 0.0 M Phage tail tape measure protein TP901
MEGJNCCF_01603 5.3e-53 S Phage tail assembly chaperone proteins, TAC
MEGJNCCF_01604 1e-125 S Phage tail tube protein
MEGJNCCF_01605 1e-63 S Protein of unknown function (DUF806)
MEGJNCCF_01606 1.1e-65 S Bacteriophage HK97-gp10, putative tail-component
MEGJNCCF_01607 4.2e-59 S Phage head-tail joining protein
MEGJNCCF_01608 1.8e-21 S Phage gp6-like head-tail connector protein
MEGJNCCF_01609 2e-222 S Phage capsid family
MEGJNCCF_01610 2.1e-118 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
MEGJNCCF_01611 4.5e-211 S Phage portal protein
MEGJNCCF_01613 0.0 S Phage Terminase
MEGJNCCF_01614 6.8e-78 L Phage terminase, small subunit
MEGJNCCF_01615 4.1e-87 L HNH nucleases
MEGJNCCF_01616 7.1e-22
MEGJNCCF_01618 2.3e-28 arpU S Phage transcriptional regulator, ArpU family
MEGJNCCF_01622 5.9e-49 S VRR_NUC
MEGJNCCF_01623 4.6e-230 S Virulence-associated protein E
MEGJNCCF_01624 1.8e-139 S Bifunctional DNA primase/polymerase, N-terminal
MEGJNCCF_01625 1.2e-83
MEGJNCCF_01626 2.7e-116 L AAA domain
MEGJNCCF_01628 3.2e-240 res L Helicase C-terminal domain protein
MEGJNCCF_01629 4.6e-77 S Siphovirus Gp157
MEGJNCCF_01634 5.7e-30 S Hypothetical protein (DUF2513)
MEGJNCCF_01636 3.1e-86 K Phage regulatory protein
MEGJNCCF_01637 1.2e-10 K Helix-turn-helix XRE-family like proteins
MEGJNCCF_01638 1.3e-28 3.4.21.88 K Helix-turn-helix domain
MEGJNCCF_01639 2e-28 E Zn peptidase
MEGJNCCF_01641 2.5e-28 S Short C-terminal domain
MEGJNCCF_01642 1.5e-24 ligA 2.7.7.7, 6.5.1.2 L EXOIII
MEGJNCCF_01643 2.1e-10
MEGJNCCF_01644 2.7e-76
MEGJNCCF_01647 2.1e-88 sip L Belongs to the 'phage' integrase family
MEGJNCCF_01649 1.3e-155 amtB P ammonium transporter
MEGJNCCF_01650 1.2e-104 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MEGJNCCF_01651 6.6e-46 argR K Regulates arginine biosynthesis genes
MEGJNCCF_01652 4.2e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
MEGJNCCF_01653 1.7e-90 S Alpha/beta hydrolase of unknown function (DUF915)
MEGJNCCF_01654 1.2e-22 veg S Biofilm formation stimulator VEG
MEGJNCCF_01655 7.5e-134 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MEGJNCCF_01656 1.7e-86 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MEGJNCCF_01657 8.3e-105 tatD L hydrolase, TatD family
MEGJNCCF_01658 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MEGJNCCF_01659 4.3e-127
MEGJNCCF_01660 2.1e-153 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MEGJNCCF_01661 7.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
MEGJNCCF_01662 2.3e-31 K Transcriptional regulator
MEGJNCCF_01663 3.5e-104 ybhR V ABC transporter
MEGJNCCF_01664 8.4e-83 ybhF_2 V abc transporter atp-binding protein
MEGJNCCF_01665 9.4e-103 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MEGJNCCF_01666 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEGJNCCF_01667 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEGJNCCF_01668 2.3e-272 helD 3.6.4.12 L DNA helicase
MEGJNCCF_01670 1.3e-114 htpX O Belongs to the peptidase M48B family
MEGJNCCF_01671 1.5e-71 lemA S LemA family
MEGJNCCF_01672 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
MEGJNCCF_01673 3.2e-45 yjcF K protein acetylation
MEGJNCCF_01675 3.3e-253 yfiC V ABC transporter
MEGJNCCF_01676 1.6e-172 lmrA V ABC transporter, ATP-binding protein
MEGJNCCF_01677 4.6e-37 lmrA V ABC transporter, ATP-binding protein
MEGJNCCF_01678 5.8e-35 K Bacterial regulatory proteins, tetR family
MEGJNCCF_01679 7.3e-246 yhcA V ABC transporter, ATP-binding protein
MEGJNCCF_01680 5.9e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEGJNCCF_01681 4.3e-116 G Transporter, major facilitator family protein
MEGJNCCF_01682 1.9e-20 G Transporter, major facilitator family protein
MEGJNCCF_01683 2.2e-90 lacX 5.1.3.3 G Aldose 1-epimerase
MEGJNCCF_01684 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
MEGJNCCF_01685 2.5e-113 K response regulator
MEGJNCCF_01686 1.2e-89 patB 4.4.1.8 E Aminotransferase, class I
MEGJNCCF_01687 1.3e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MEGJNCCF_01688 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MEGJNCCF_01689 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MEGJNCCF_01690 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MEGJNCCF_01691 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
MEGJNCCF_01692 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEGJNCCF_01693 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEGJNCCF_01694 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEGJNCCF_01695 1.6e-55 ctsR K Belongs to the CtsR family
MEGJNCCF_01697 2.5e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MEGJNCCF_01698 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MEGJNCCF_01699 3.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MEGJNCCF_01700 1.4e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEGJNCCF_01701 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MEGJNCCF_01709 2.9e-311 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEGJNCCF_01710 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
MEGJNCCF_01711 1.7e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEGJNCCF_01712 5.4e-128 cpoA GT4 M Glycosyltransferase, group 1 family protein
MEGJNCCF_01713 8.8e-162 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MEGJNCCF_01714 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEGJNCCF_01715 9.7e-37 ptsH G phosphocarrier protein HPR
MEGJNCCF_01716 1.5e-15
MEGJNCCF_01717 0.0 clpE O Belongs to the ClpA ClpB family
MEGJNCCF_01718 6.6e-23 XK27_09445 S Domain of unknown function (DUF1827)
MEGJNCCF_01719 2.9e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
MEGJNCCF_01720 0.0 rafA 3.2.1.22 G alpha-galactosidase
MEGJNCCF_01721 1.6e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MEGJNCCF_01722 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MEGJNCCF_01723 2.6e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MEGJNCCF_01724 5.9e-111 galR K Transcriptional regulator
MEGJNCCF_01725 4e-289 lacS G Transporter
MEGJNCCF_01726 0.0 lacL 3.2.1.23 G -beta-galactosidase
MEGJNCCF_01727 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MEGJNCCF_01728 1.4e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MEGJNCCF_01729 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MEGJNCCF_01730 3.4e-91 yueF S AI-2E family transporter
MEGJNCCF_01731 2.6e-97 ygaC J Belongs to the UPF0374 family
MEGJNCCF_01732 9.4e-192 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEGJNCCF_01733 2.2e-68 recX 2.4.1.337 GT4 S Regulatory protein RecX
MEGJNCCF_01734 1.1e-19 yvrI K RNA polymerase sigma factor, sigma-70 family
MEGJNCCF_01735 7e-23 S Cytochrome B5
MEGJNCCF_01736 2.3e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
MEGJNCCF_01737 7.6e-60
MEGJNCCF_01738 1.3e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MEGJNCCF_01739 6.6e-156 nrnB S DHHA1 domain
MEGJNCCF_01740 1.5e-91 yunF F Protein of unknown function DUF72
MEGJNCCF_01741 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
MEGJNCCF_01742 5.4e-13
MEGJNCCF_01743 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEGJNCCF_01744 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MEGJNCCF_01745 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MEGJNCCF_01746 4.1e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MEGJNCCF_01747 4.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
MEGJNCCF_01748 7.7e-61 M ErfK YbiS YcfS YnhG
MEGJNCCF_01750 2.6e-84 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MEGJNCCF_01751 1.2e-180 pbuG S permease
MEGJNCCF_01753 1.8e-78 S Cell surface protein
MEGJNCCF_01755 6.4e-257 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
MEGJNCCF_01756 6.3e-61
MEGJNCCF_01757 3.6e-41 rpmE2 J Ribosomal protein L31
MEGJNCCF_01758 5.3e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MEGJNCCF_01759 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEGJNCCF_01761 3.6e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MEGJNCCF_01762 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MEGJNCCF_01763 1.8e-32 ywiB S Domain of unknown function (DUF1934)
MEGJNCCF_01764 2e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
MEGJNCCF_01765 3.3e-205 ywfO S HD domain protein
MEGJNCCF_01766 7.5e-88 S hydrolase
MEGJNCCF_01767 2e-105 ydcZ S Putative inner membrane exporter, YdcZ
MEGJNCCF_01768 1.3e-63
MEGJNCCF_01770 5.8e-36 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
MEGJNCCF_01771 2.3e-22
MEGJNCCF_01772 3e-56 spoVK O ATPase family associated with various cellular activities (AAA)
MEGJNCCF_01774 2.2e-86 S overlaps another CDS with the same product name
MEGJNCCF_01775 1.6e-125 S overlaps another CDS with the same product name
MEGJNCCF_01776 1.9e-98 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MEGJNCCF_01777 1.1e-62 bCE_4747 S Beta-lactamase superfamily domain
MEGJNCCF_01778 2e-289 ybiT S ABC transporter, ATP-binding protein
MEGJNCCF_01779 1e-78 2.4.2.3 F Phosphorylase superfamily
MEGJNCCF_01780 1.1e-23
MEGJNCCF_01781 7.6e-112 dkg S reductase
MEGJNCCF_01782 7.7e-19 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MEGJNCCF_01783 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEGJNCCF_01784 1.1e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MEGJNCCF_01785 2.1e-46 EGP Transmembrane secretion effector
MEGJNCCF_01786 5.2e-137 purR 2.4.2.7 F pur operon repressor
MEGJNCCF_01787 3.9e-53 adhR K helix_turn_helix, mercury resistance
MEGJNCCF_01788 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MEGJNCCF_01789 2.5e-104 pfoS S Phosphotransferase system, EIIC
MEGJNCCF_01790 2.2e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEGJNCCF_01791 6.2e-152 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MEGJNCCF_01792 1.9e-196 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MEGJNCCF_01793 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
MEGJNCCF_01794 3.8e-93 yihY S Belongs to the UPF0761 family
MEGJNCCF_01795 1.8e-12 mltD CBM50 M Lysin motif
MEGJNCCF_01796 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MEGJNCCF_01797 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
MEGJNCCF_01798 5.1e-54 fld C Flavodoxin
MEGJNCCF_01799 8.7e-53 gtcA S Teichoic acid glycosylation protein
MEGJNCCF_01800 0.0 S Bacterial membrane protein YfhO
MEGJNCCF_01801 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
MEGJNCCF_01802 1.7e-122 S Sulfite exporter TauE/SafE
MEGJNCCF_01803 1.1e-70 K Sugar-specific transcriptional regulator TrmB
MEGJNCCF_01804 9.3e-169 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MEGJNCCF_01805 3.5e-182 pepS E Thermophilic metalloprotease (M29)
MEGJNCCF_01806 3e-266 E Amino acid permease
MEGJNCCF_01807 2.4e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MEGJNCCF_01808 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MEGJNCCF_01809 2.9e-78 galM 5.1.3.3 G Aldose 1-epimerase
MEGJNCCF_01810 4.3e-213 malT G Transporter, major facilitator family protein
MEGJNCCF_01811 4.2e-101 malR K Transcriptional regulator, LacI family
MEGJNCCF_01812 2.3e-279 kup P Transport of potassium into the cell
MEGJNCCF_01814 2e-20 S Domain of unknown function (DUF3284)
MEGJNCCF_01815 5.2e-160 yfmL L DEAD DEAH box helicase
MEGJNCCF_01816 7e-128 mocA S Oxidoreductase
MEGJNCCF_01817 2e-24 S Domain of unknown function (DUF4828)
MEGJNCCF_01818 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
MEGJNCCF_01819 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MEGJNCCF_01820 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
MEGJNCCF_01821 1.1e-116 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
MEGJNCCF_01822 7.1e-161 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MEGJNCCF_01823 2.8e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MEGJNCCF_01824 3e-219 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MEGJNCCF_01825 4.9e-42 O ADP-ribosylglycohydrolase
MEGJNCCF_01826 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
MEGJNCCF_01827 6.4e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MEGJNCCF_01828 9.7e-35 K GNAT family
MEGJNCCF_01829 1.7e-40
MEGJNCCF_01831 1.6e-159 mgtE P Acts as a magnesium transporter
MEGJNCCF_01832 7.6e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MEGJNCCF_01833 1.3e-116 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEGJNCCF_01834 1.6e-93 yjbM 2.7.6.5 S RelA SpoT domain protein
MEGJNCCF_01835 9e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MEGJNCCF_01836 1.7e-35 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MEGJNCCF_01837 6.3e-193 pbuX F xanthine permease
MEGJNCCF_01838 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MEGJNCCF_01839 1.6e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
MEGJNCCF_01840 5.5e-64 S ECF transporter, substrate-specific component
MEGJNCCF_01841 1.7e-126 mleP S Sodium Bile acid symporter family
MEGJNCCF_01842 1.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MEGJNCCF_01843 1.8e-71 mleR K LysR family
MEGJNCCF_01844 1.1e-56 K transcriptional
MEGJNCCF_01845 5.9e-41 K Bacterial regulatory proteins, tetR family
MEGJNCCF_01846 6.1e-60 T Belongs to the universal stress protein A family
MEGJNCCF_01847 8.1e-44 K Copper transport repressor CopY TcrY
MEGJNCCF_01848 9.1e-106 3.2.1.18 GH33 M Rib/alpha-like repeat
MEGJNCCF_01849 1.4e-113 3.2.1.18 GH33 M Rib/alpha-like repeat
MEGJNCCF_01851 1.9e-95 ypuA S Protein of unknown function (DUF1002)
MEGJNCCF_01852 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
MEGJNCCF_01853 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEGJNCCF_01854 4.6e-36 yncA 2.3.1.79 S Maltose acetyltransferase
MEGJNCCF_01855 6.9e-206 yflS P Sodium:sulfate symporter transmembrane region
MEGJNCCF_01856 7.2e-200 frdC 1.3.5.4 C FAD binding domain
MEGJNCCF_01857 3.3e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MEGJNCCF_01858 2.6e-14 ybaN S Protein of unknown function (DUF454)
MEGJNCCF_01859 8.2e-177 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MEGJNCCF_01860 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MEGJNCCF_01861 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEGJNCCF_01862 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MEGJNCCF_01863 5.1e-72 ywlG S Belongs to the UPF0340 family
MEGJNCCF_01864 5.2e-65 S Acetyltransferase (GNAT) domain
MEGJNCCF_01866 3.5e-50 K Cro/C1-type HTH DNA-binding domain
MEGJNCCF_01867 1.6e-174 spoVK O ATPase family associated with various cellular activities (AAA)
MEGJNCCF_01870 8.3e-126 S Bacteriophage abortive infection AbiH
MEGJNCCF_01871 3.2e-61 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain protein
MEGJNCCF_01872 4.2e-208 G glycerol-3-phosphate transporter
MEGJNCCF_01873 1.7e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MEGJNCCF_01874 5.9e-88 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
MEGJNCCF_01875 3.3e-25 K MarR family transcriptional regulator
MEGJNCCF_01876 4.4e-40 1.6.5.2 GM NAD(P)H-binding
MEGJNCCF_01877 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MEGJNCCF_01878 3.7e-145 htrA 3.4.21.107 O serine protease
MEGJNCCF_01879 1.3e-116 vicX 3.1.26.11 S domain protein
MEGJNCCF_01880 1.8e-30 yyaQ S YjbR
MEGJNCCF_01881 5.6e-80 yycI S YycH protein
MEGJNCCF_01882 4.6e-103 yycH S YycH protein
MEGJNCCF_01883 1.1e-272 vicK 2.7.13.3 T Histidine kinase
MEGJNCCF_01884 9e-114 K response regulator
MEGJNCCF_01885 6.3e-85 yxeH S hydrolase
MEGJNCCF_01887 3.3e-96 S Domain of unknown function DUF87
MEGJNCCF_01889 1.1e-229 V ABC transporter transmembrane region
MEGJNCCF_01890 3.1e-216 XK27_09600 V ABC transporter, ATP-binding protein
MEGJNCCF_01891 1.2e-31 K Transcriptional regulator, MarR family
MEGJNCCF_01892 2.9e-172 S Putative peptidoglycan binding domain
MEGJNCCF_01894 4e-23 relB L RelB antitoxin
MEGJNCCF_01895 8.4e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MEGJNCCF_01896 1.1e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
MEGJNCCF_01897 4.4e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MEGJNCCF_01898 1.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MEGJNCCF_01899 3.5e-223 pepF E Oligopeptidase F
MEGJNCCF_01900 2.2e-96 yicL EG EamA-like transporter family
MEGJNCCF_01901 2.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
MEGJNCCF_01902 4.4e-170 yjjP S Putative threonine/serine exporter
MEGJNCCF_01903 1.4e-108 glcU U sugar transport
MEGJNCCF_01904 3.8e-14 yobS K transcriptional regulator
MEGJNCCF_01905 3.8e-152 mdtG EGP Major facilitator Superfamily
MEGJNCCF_01906 3.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MEGJNCCF_01907 2.2e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
MEGJNCCF_01908 1.5e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEGJNCCF_01909 3.6e-17 yneR
MEGJNCCF_01910 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MEGJNCCF_01911 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MEGJNCCF_01912 3.3e-12 yiiE S Protein of unknown function (DUF1211)
MEGJNCCF_01913 3.7e-37 yiiE S Protein of unknown function (DUF1211)
MEGJNCCF_01914 0.0 asnB 6.3.5.4 E Asparagine synthase
MEGJNCCF_01915 7.4e-64 D peptidase
MEGJNCCF_01916 7.3e-117 S Glycosyl transferase family 2
MEGJNCCF_01917 2.5e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
MEGJNCCF_01918 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MEGJNCCF_01919 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MEGJNCCF_01920 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
MEGJNCCF_01921 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEGJNCCF_01922 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEGJNCCF_01923 9.3e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MEGJNCCF_01924 9e-20 yaaA S S4 domain protein YaaA
MEGJNCCF_01925 3.9e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEGJNCCF_01926 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MEGJNCCF_01927 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MEGJNCCF_01928 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MEGJNCCF_01929 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEGJNCCF_01930 1.1e-199 nupG F Nucleoside
MEGJNCCF_01931 2e-122 MA20_14895 S Conserved hypothetical protein 698
MEGJNCCF_01932 2.9e-53 K LysR substrate binding domain
MEGJNCCF_01933 9.6e-09
MEGJNCCF_01934 2.3e-65 yxkH G Polysaccharide deacetylase
MEGJNCCF_01935 2.6e-29 yqkB S Belongs to the HesB IscA family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)