ORF_ID e_value Gene_name EC_number CAZy COGs Description
KNIFDBKJ_00002 1.6e-197 dtpT U amino acid peptide transporter
KNIFDBKJ_00003 1.1e-07
KNIFDBKJ_00005 1e-89 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KNIFDBKJ_00006 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
KNIFDBKJ_00007 1.4e-90 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KNIFDBKJ_00008 9.5e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KNIFDBKJ_00009 1.8e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KNIFDBKJ_00010 1.7e-251 yhgF K Tex-like protein N-terminal domain protein
KNIFDBKJ_00011 3e-43 ydcK S Belongs to the SprT family
KNIFDBKJ_00013 3.5e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNIFDBKJ_00014 2.9e-128 mleP2 S Sodium Bile acid symporter family
KNIFDBKJ_00015 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KNIFDBKJ_00016 1e-33 S Enterocin A Immunity
KNIFDBKJ_00017 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
KNIFDBKJ_00018 8.1e-18 HA62_12640 S GCN5-related N-acetyl-transferase
KNIFDBKJ_00019 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KNIFDBKJ_00020 3.5e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KNIFDBKJ_00021 3.1e-153 yacL S domain protein
KNIFDBKJ_00022 1.4e-246 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KNIFDBKJ_00023 2.8e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KNIFDBKJ_00024 3.8e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KNIFDBKJ_00025 1.2e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNIFDBKJ_00026 7e-71 yacP S YacP-like NYN domain
KNIFDBKJ_00027 3.1e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KNIFDBKJ_00028 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KNIFDBKJ_00029 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
KNIFDBKJ_00030 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KNIFDBKJ_00031 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KNIFDBKJ_00032 1.7e-74 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KNIFDBKJ_00033 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KNIFDBKJ_00034 1.6e-55
KNIFDBKJ_00035 2.7e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KNIFDBKJ_00036 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNIFDBKJ_00037 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNIFDBKJ_00038 4.8e-45 nrdI F NrdI Flavodoxin like
KNIFDBKJ_00039 1.2e-27 nrdH O Glutaredoxin
KNIFDBKJ_00040 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
KNIFDBKJ_00041 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KNIFDBKJ_00042 4.6e-212 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNIFDBKJ_00043 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KNIFDBKJ_00044 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KNIFDBKJ_00045 7.1e-29 yaaL S Protein of unknown function (DUF2508)
KNIFDBKJ_00046 8.1e-66 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KNIFDBKJ_00047 3e-83 holB 2.7.7.7 L DNA polymerase III
KNIFDBKJ_00048 1.4e-40 yabA L Involved in initiation control of chromosome replication
KNIFDBKJ_00049 3.3e-105 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KNIFDBKJ_00050 7.2e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
KNIFDBKJ_00051 1.2e-140 ansA 3.5.1.1 EJ Asparaginase
KNIFDBKJ_00052 2.4e-69 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KNIFDBKJ_00053 1.1e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KNIFDBKJ_00054 9.2e-160 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KNIFDBKJ_00055 2.6e-256 uup S ABC transporter, ATP-binding protein
KNIFDBKJ_00056 9.7e-99 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KNIFDBKJ_00057 1.3e-31 S CAAX protease self-immunity
KNIFDBKJ_00058 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KNIFDBKJ_00059 3.1e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KNIFDBKJ_00060 3.7e-268 aha1 P COG COG0474 Cation transport ATPase
KNIFDBKJ_00061 4.9e-297 ydaO E amino acid
KNIFDBKJ_00062 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
KNIFDBKJ_00063 1.9e-128 comFA L Helicase C-terminal domain protein
KNIFDBKJ_00064 3e-50 comFC S Competence protein
KNIFDBKJ_00065 2.1e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KNIFDBKJ_00066 9.1e-95 yeaN P Major Facilitator Superfamily
KNIFDBKJ_00067 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KNIFDBKJ_00068 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KNIFDBKJ_00069 9.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
KNIFDBKJ_00070 1.3e-85 K response regulator
KNIFDBKJ_00071 5.3e-86 phoR 2.7.13.3 T Histidine kinase
KNIFDBKJ_00072 4.1e-08 KT PspC domain protein
KNIFDBKJ_00073 3.5e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KNIFDBKJ_00074 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KNIFDBKJ_00075 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KNIFDBKJ_00076 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KNIFDBKJ_00077 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KNIFDBKJ_00078 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KNIFDBKJ_00079 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KNIFDBKJ_00080 1.3e-79 ylbE GM NAD dependent epimerase dehydratase family protein
KNIFDBKJ_00081 7.5e-126 rapZ S Displays ATPase and GTPase activities
KNIFDBKJ_00082 6.3e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KNIFDBKJ_00083 1.8e-149 whiA K May be required for sporulation
KNIFDBKJ_00084 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KNIFDBKJ_00086 2.4e-136 cggR K Putative sugar-binding domain
KNIFDBKJ_00087 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KNIFDBKJ_00088 1.1e-207 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KNIFDBKJ_00089 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KNIFDBKJ_00090 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KNIFDBKJ_00091 1.4e-131 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KNIFDBKJ_00092 7.2e-103 K response regulator
KNIFDBKJ_00093 1.8e-169 T PhoQ Sensor
KNIFDBKJ_00094 1.1e-145 lmrP E Major Facilitator Superfamily
KNIFDBKJ_00095 9.2e-180 clcA P chloride
KNIFDBKJ_00096 2.8e-19 secG U Preprotein translocase
KNIFDBKJ_00097 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KNIFDBKJ_00098 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KNIFDBKJ_00099 3.1e-42 yxjI
KNIFDBKJ_00100 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
KNIFDBKJ_00101 8.9e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KNIFDBKJ_00102 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KNIFDBKJ_00103 4.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KNIFDBKJ_00104 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
KNIFDBKJ_00105 6e-115 murB 1.3.1.98 M Cell wall formation
KNIFDBKJ_00106 2.4e-71 S Protein of unknown function (DUF1361)
KNIFDBKJ_00107 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KNIFDBKJ_00108 5.3e-68 ybbR S YbbR-like protein
KNIFDBKJ_00109 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KNIFDBKJ_00110 5.8e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KNIFDBKJ_00111 4.9e-129 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KNIFDBKJ_00112 2.3e-19 cutC P Participates in the control of copper homeostasis
KNIFDBKJ_00114 6.4e-94 S Bacterial membrane protein, YfhO
KNIFDBKJ_00115 4.8e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KNIFDBKJ_00116 1.7e-163 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KNIFDBKJ_00117 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
KNIFDBKJ_00118 5.8e-99 rrmA 2.1.1.187 H Methyltransferase
KNIFDBKJ_00119 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KNIFDBKJ_00120 6.8e-288 ftsK D Belongs to the FtsK SpoIIIE SftA family
KNIFDBKJ_00121 2e-108 ymfF S Peptidase M16 inactive domain protein
KNIFDBKJ_00122 9.3e-149 ymfH S Peptidase M16
KNIFDBKJ_00123 4.9e-91 IQ Enoyl-(Acyl carrier protein) reductase
KNIFDBKJ_00124 8.5e-64 ymfM S Helix-turn-helix domain
KNIFDBKJ_00125 8e-84 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KNIFDBKJ_00126 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KNIFDBKJ_00127 7.6e-182 rny S Endoribonuclease that initiates mRNA decay
KNIFDBKJ_00128 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KNIFDBKJ_00129 6.4e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KNIFDBKJ_00130 1.6e-71 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KNIFDBKJ_00131 8.2e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KNIFDBKJ_00132 5.1e-182 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KNIFDBKJ_00133 7.8e-208 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KNIFDBKJ_00134 1.4e-12 yajC U Preprotein translocase
KNIFDBKJ_00136 4.3e-61 uspA T universal stress protein
KNIFDBKJ_00138 2e-208 yfnA E Amino Acid
KNIFDBKJ_00139 6.9e-117 lutA C Cysteine-rich domain
KNIFDBKJ_00140 1.1e-244 lutB C 4Fe-4S dicluster domain
KNIFDBKJ_00141 1.6e-65 yrjD S LUD domain
KNIFDBKJ_00142 3.9e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KNIFDBKJ_00143 7.5e-13
KNIFDBKJ_00144 1.2e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KNIFDBKJ_00145 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KNIFDBKJ_00146 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KNIFDBKJ_00147 2.1e-36 yrzL S Belongs to the UPF0297 family
KNIFDBKJ_00148 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KNIFDBKJ_00149 2.5e-33 yrzB S Belongs to the UPF0473 family
KNIFDBKJ_00150 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KNIFDBKJ_00151 1.6e-17 cvpA S Colicin V production protein
KNIFDBKJ_00152 7.2e-309 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KNIFDBKJ_00153 1.3e-40 trxA O Belongs to the thioredoxin family
KNIFDBKJ_00154 5.2e-60 yslB S Protein of unknown function (DUF2507)
KNIFDBKJ_00155 5.5e-72 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KNIFDBKJ_00156 4.4e-41 S Phosphoesterase
KNIFDBKJ_00159 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNIFDBKJ_00160 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KNIFDBKJ_00161 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KNIFDBKJ_00162 1.3e-199 oatA I Acyltransferase
KNIFDBKJ_00163 1.4e-16
KNIFDBKJ_00165 9.8e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KNIFDBKJ_00166 1.7e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
KNIFDBKJ_00167 1.7e-217 recJ L Single-stranded-DNA-specific exonuclease RecJ
KNIFDBKJ_00168 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KNIFDBKJ_00169 8.4e-298 S membrane
KNIFDBKJ_00170 1.2e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
KNIFDBKJ_00172 1.8e-45 yviA S Protein of unknown function (DUF421)
KNIFDBKJ_00173 1.5e-16
KNIFDBKJ_00175 3.3e-75 S DNA primase
KNIFDBKJ_00176 1.5e-45 L Bifunctional DNA primase/polymerase, N-terminal
KNIFDBKJ_00183 3.4e-12 xre K sequence-specific DNA binding
KNIFDBKJ_00184 1.8e-44 S Phage regulatory protein Rha (Phage_pRha)
KNIFDBKJ_00185 3.1e-08 S Helix-turn-helix domain
KNIFDBKJ_00186 1.3e-22 K Cro/C1-type HTH DNA-binding domain
KNIFDBKJ_00187 1.8e-111 sip L Belongs to the 'phage' integrase family
KNIFDBKJ_00190 5e-124 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KNIFDBKJ_00191 5e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KNIFDBKJ_00192 1.2e-52 tag 3.2.2.20 L glycosylase
KNIFDBKJ_00193 5.5e-73 usp6 T universal stress protein
KNIFDBKJ_00195 5.8e-188 rarA L recombination factor protein RarA
KNIFDBKJ_00196 5.9e-24 yueI S Protein of unknown function (DUF1694)
KNIFDBKJ_00197 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KNIFDBKJ_00198 1.6e-55 ytsP 1.8.4.14 T GAF domain-containing protein
KNIFDBKJ_00199 6e-172 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KNIFDBKJ_00200 2.2e-162 iscS2 2.8.1.7 E Aminotransferase class V
KNIFDBKJ_00201 4.2e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNIFDBKJ_00202 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KNIFDBKJ_00203 1.4e-136 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KNIFDBKJ_00204 6.2e-80 radC L DNA repair protein
KNIFDBKJ_00205 4.5e-21 K Cold shock
KNIFDBKJ_00206 3.6e-156 mreB D cell shape determining protein MreB
KNIFDBKJ_00207 2.1e-88 mreC M Involved in formation and maintenance of cell shape
KNIFDBKJ_00208 4.4e-54 mreD M rod shape-determining protein MreD
KNIFDBKJ_00209 1.9e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KNIFDBKJ_00210 3.1e-126 minD D Belongs to the ParA family
KNIFDBKJ_00211 1.9e-94 glnP P ABC transporter permease
KNIFDBKJ_00212 1.1e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KNIFDBKJ_00213 1.4e-108 aatB ET ABC transporter substrate-binding protein
KNIFDBKJ_00214 7.5e-100 D Alpha beta
KNIFDBKJ_00216 2.7e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
KNIFDBKJ_00217 4.5e-08 S Protein of unknown function (DUF3397)
KNIFDBKJ_00218 5.2e-64 mraZ K Belongs to the MraZ family
KNIFDBKJ_00219 3.6e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KNIFDBKJ_00220 2.5e-11 ftsL D cell division protein FtsL
KNIFDBKJ_00221 1.3e-280 ftsI 3.4.16.4 M Penicillin-binding Protein
KNIFDBKJ_00222 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KNIFDBKJ_00223 1.7e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KNIFDBKJ_00224 6.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KNIFDBKJ_00225 5.7e-62 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KNIFDBKJ_00226 4.4e-189 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KNIFDBKJ_00227 2.9e-179 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KNIFDBKJ_00228 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KNIFDBKJ_00229 3e-19 yggT S YGGT family
KNIFDBKJ_00230 7.7e-82 ylmH S S4 domain protein
KNIFDBKJ_00231 5.1e-62 divIVA D DivIVA domain protein
KNIFDBKJ_00232 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KNIFDBKJ_00233 4.4e-91 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNIFDBKJ_00234 3.3e-74 draG O ADP-ribosylglycohydrolase
KNIFDBKJ_00236 1.9e-85 2.7.7.12 C Domain of unknown function (DUF4931)
KNIFDBKJ_00237 4.8e-93 T Calcineurin-like phosphoesterase superfamily domain
KNIFDBKJ_00238 2.1e-48 lytE M LysM domain protein
KNIFDBKJ_00239 2.3e-19 glpE P Rhodanese Homology Domain
KNIFDBKJ_00240 5.7e-29 xlyB 3.5.1.28 CBM50 M LysM domain
KNIFDBKJ_00241 2.6e-159 asnA 6.3.1.1 F aspartate--ammonia ligase
KNIFDBKJ_00242 3e-193 cydA 1.10.3.14 C ubiquinol oxidase
KNIFDBKJ_00243 5.6e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
KNIFDBKJ_00244 7.8e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KNIFDBKJ_00245 3.6e-220 cydD CO ABC transporter transmembrane region
KNIFDBKJ_00246 6.2e-97 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KNIFDBKJ_00247 3.3e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KNIFDBKJ_00248 2.5e-156 ndh 1.6.99.3 C NADH dehydrogenase
KNIFDBKJ_00249 1.5e-146 pbuO_1 S Permease family
KNIFDBKJ_00250 8.1e-43 2.7.7.65 T GGDEF domain
KNIFDBKJ_00251 1.7e-129 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
KNIFDBKJ_00252 2.1e-181
KNIFDBKJ_00253 1e-205 S Protein conserved in bacteria
KNIFDBKJ_00254 7.7e-201 ydaM M Glycosyl transferase family group 2
KNIFDBKJ_00255 3.4e-310 ydaN S Bacterial cellulose synthase subunit
KNIFDBKJ_00256 2.4e-113 2.7.7.65 T diguanylate cyclase activity
KNIFDBKJ_00257 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
KNIFDBKJ_00258 1.9e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
KNIFDBKJ_00259 2.6e-308 L Helicase C-terminal domain protein
KNIFDBKJ_00260 0.0 rafA 3.2.1.22 G alpha-galactosidase
KNIFDBKJ_00261 8.9e-54 S Membrane
KNIFDBKJ_00262 3.5e-64 K helix_turn_helix, arabinose operon control protein
KNIFDBKJ_00263 2.3e-45
KNIFDBKJ_00264 5e-204 pipD E Dipeptidase
KNIFDBKJ_00265 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KNIFDBKJ_00266 2.4e-189 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KNIFDBKJ_00267 3e-61 speG J Acetyltransferase (GNAT) domain
KNIFDBKJ_00268 5.1e-113 yitU 3.1.3.104 S hydrolase
KNIFDBKJ_00269 1.8e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KNIFDBKJ_00270 4.8e-81
KNIFDBKJ_00271 3.8e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KNIFDBKJ_00272 6.7e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
KNIFDBKJ_00273 1.8e-48 cps4C M Chain length determinant protein
KNIFDBKJ_00274 9.4e-65 cpsD D AAA domain
KNIFDBKJ_00275 6e-89 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
KNIFDBKJ_00276 9.8e-127 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
KNIFDBKJ_00277 2.6e-166 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
KNIFDBKJ_00278 4.8e-77 epsL M Bacterial sugar transferase
KNIFDBKJ_00279 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
KNIFDBKJ_00280 1.9e-123 2.4.1.52 GT4 M Glycosyl transferases group 1
KNIFDBKJ_00281 8.1e-80 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
KNIFDBKJ_00283 9.3e-60 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
KNIFDBKJ_00284 1.3e-74 M Glycosyltransferase Family 4
KNIFDBKJ_00285 1.7e-42 GT2 V Glycosyl transferase, family 2
KNIFDBKJ_00286 2.5e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
KNIFDBKJ_00288 1.6e-52
KNIFDBKJ_00289 2.3e-116 S Glycosyltransferase WbsX
KNIFDBKJ_00290 4.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
KNIFDBKJ_00291 9e-103 cps2I S Psort location CytoplasmicMembrane, score
KNIFDBKJ_00292 6.1e-146 lspL 5.1.3.6 GM RmlD substrate binding domain
KNIFDBKJ_00293 2.8e-179 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KNIFDBKJ_00294 6.9e-65 M Glycosyl transferases group 1
KNIFDBKJ_00295 5.6e-126 M Glycosyl transferases group 1
KNIFDBKJ_00298 7.5e-83 qorB 1.6.5.2 GM NmrA-like family
KNIFDBKJ_00299 3.6e-39 K Transcriptional regulator
KNIFDBKJ_00300 5e-71 1.1.1.1 C Zinc-binding dehydrogenase
KNIFDBKJ_00302 3.7e-40 S Protein of unknown function (DUF1211)
KNIFDBKJ_00303 7.3e-27 ybl78 L Conserved phage C-terminus (Phg_2220_C)
KNIFDBKJ_00305 6.2e-40 wecD M Acetyltransferase (GNAT) family
KNIFDBKJ_00306 1.6e-65 H Methyltransferase domain
KNIFDBKJ_00308 2.9e-16 K DNA-templated transcription, initiation
KNIFDBKJ_00310 2.2e-08 S Protein of unknown function (DUF2922)
KNIFDBKJ_00313 4.9e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
KNIFDBKJ_00314 2.9e-27 ysxB J Cysteine protease Prp
KNIFDBKJ_00315 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KNIFDBKJ_00316 1e-12
KNIFDBKJ_00319 3.1e-71
KNIFDBKJ_00320 1.4e-101 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KNIFDBKJ_00321 5.9e-88 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KNIFDBKJ_00322 3e-70 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KNIFDBKJ_00323 1e-122 xerC D Belongs to the 'phage' integrase family. XerC subfamily
KNIFDBKJ_00324 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KNIFDBKJ_00325 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KNIFDBKJ_00326 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KNIFDBKJ_00327 1.2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KNIFDBKJ_00328 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KNIFDBKJ_00329 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KNIFDBKJ_00330 1.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KNIFDBKJ_00331 7e-51 yeaL S Protein of unknown function (DUF441)
KNIFDBKJ_00332 9.6e-126 cvfB S S1 domain
KNIFDBKJ_00333 9.6e-113 xerD D recombinase XerD
KNIFDBKJ_00334 3.8e-294 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KNIFDBKJ_00335 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KNIFDBKJ_00336 2.2e-54 nhaC C Na H antiporter NhaC
KNIFDBKJ_00337 1.8e-125 nhaC C Na H antiporter NhaC
KNIFDBKJ_00338 6e-65 ypsA S Belongs to the UPF0398 family
KNIFDBKJ_00339 1.3e-195 ade 3.5.4.2 F Adenine deaminase C-terminal domain
KNIFDBKJ_00341 6.3e-73 2.3.1.178 M GNAT acetyltransferase
KNIFDBKJ_00342 6.7e-68 maa 2.3.1.79 S Maltose acetyltransferase
KNIFDBKJ_00343 2.8e-56 3.6.1.27 I Acid phosphatase homologues
KNIFDBKJ_00344 1.1e-80 XK27_07525 3.6.1.55 F Hydrolase, nudix family
KNIFDBKJ_00346 2.2e-68 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNIFDBKJ_00347 3.7e-109 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
KNIFDBKJ_00348 5.9e-38 K Transcriptional regulator
KNIFDBKJ_00349 5.9e-53 EGP Major Facilitator Superfamily
KNIFDBKJ_00350 3.1e-167 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KNIFDBKJ_00351 3.3e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KNIFDBKJ_00352 7.6e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KNIFDBKJ_00353 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KNIFDBKJ_00355 4.3e-88 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KNIFDBKJ_00356 2.2e-44
KNIFDBKJ_00357 1.1e-120 ica2 GT2 M Glycosyl transferase family group 2
KNIFDBKJ_00358 7.9e-45 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
KNIFDBKJ_00359 6.4e-221 mntH P H( )-stimulated, divalent metal cation uptake system
KNIFDBKJ_00360 7.6e-61 ypbB 5.1.3.1 S Helix-turn-helix domain
KNIFDBKJ_00361 2e-128 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KNIFDBKJ_00362 7.7e-12 M Lysin motif
KNIFDBKJ_00363 3.7e-85 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KNIFDBKJ_00364 4.4e-83 lytH 3.5.1.28 M Ami_3
KNIFDBKJ_00365 5.4e-154 phoH T phosphate starvation-inducible protein PhoH
KNIFDBKJ_00366 1.9e-59 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KNIFDBKJ_00367 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KNIFDBKJ_00368 3.5e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KNIFDBKJ_00369 6.9e-91 recO L Involved in DNA repair and RecF pathway recombination
KNIFDBKJ_00370 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
KNIFDBKJ_00371 3.4e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNIFDBKJ_00372 7e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
KNIFDBKJ_00373 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNIFDBKJ_00374 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KNIFDBKJ_00375 5.3e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
KNIFDBKJ_00376 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
KNIFDBKJ_00377 5.9e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KNIFDBKJ_00378 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KNIFDBKJ_00380 1.8e-22 K Acetyltransferase (GNAT) domain
KNIFDBKJ_00381 3.7e-112 natA S Domain of unknown function (DUF4162)
KNIFDBKJ_00382 6.5e-80 natB CP ABC-type Na efflux pump, permease component
KNIFDBKJ_00383 7e-95 EG EamA-like transporter family
KNIFDBKJ_00384 4.5e-80 yjjH S Calcineurin-like phosphoesterase
KNIFDBKJ_00385 1.3e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KNIFDBKJ_00386 2.4e-40 6.3.3.2 S ASCH
KNIFDBKJ_00387 2.5e-69 lepB 3.4.21.89 U Signal peptidase, peptidase S26
KNIFDBKJ_00388 8.2e-117 degV S EDD domain protein, DegV family
KNIFDBKJ_00389 8.9e-40 K Transcriptional regulator
KNIFDBKJ_00390 9.4e-202 FbpA K Fibronectin-binding protein
KNIFDBKJ_00391 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KNIFDBKJ_00392 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KNIFDBKJ_00393 4.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KNIFDBKJ_00394 1e-39 ypaA S Protein of unknown function (DUF1304)
KNIFDBKJ_00396 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KNIFDBKJ_00397 1.5e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KNIFDBKJ_00398 0.0 dnaE 2.7.7.7 L DNA polymerase
KNIFDBKJ_00399 4.3e-15 S Protein of unknown function (DUF2929)
KNIFDBKJ_00400 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KNIFDBKJ_00401 2.6e-34 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KNIFDBKJ_00402 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KNIFDBKJ_00403 1.4e-40 XK27_04120 S Putative amino acid metabolism
KNIFDBKJ_00404 4.6e-160 iscS 2.8.1.7 E Aminotransferase class V
KNIFDBKJ_00405 4.6e-91 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KNIFDBKJ_00407 2.6e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KNIFDBKJ_00408 3.6e-129 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KNIFDBKJ_00409 2.5e-160 nhaC C Na H antiporter NhaC
KNIFDBKJ_00410 7e-127 corA P CorA-like Mg2+ transporter protein
KNIFDBKJ_00411 1.5e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KNIFDBKJ_00412 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
KNIFDBKJ_00413 1.1e-149 S Tetratricopeptide repeat protein
KNIFDBKJ_00414 4.9e-136 EG EamA-like transporter family
KNIFDBKJ_00415 2.5e-70 alkD L DNA alkylation repair enzyme
KNIFDBKJ_00416 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KNIFDBKJ_00417 1.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KNIFDBKJ_00418 1e-77 trmK 2.1.1.217 S SAM-dependent methyltransferase
KNIFDBKJ_00419 1.1e-149 EGP Sugar (and other) transporter
KNIFDBKJ_00422 6.1e-39
KNIFDBKJ_00423 5.9e-257 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KNIFDBKJ_00424 9.5e-22 S Family of unknown function (DUF5322)
KNIFDBKJ_00425 1.4e-36 rnhA 3.1.26.4 L Ribonuclease HI
KNIFDBKJ_00426 2.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KNIFDBKJ_00427 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KNIFDBKJ_00429 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KNIFDBKJ_00430 1.8e-172 patA 2.6.1.1 E Aminotransferase
KNIFDBKJ_00431 8.6e-115 glcR K DeoR C terminal sensor domain
KNIFDBKJ_00432 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
KNIFDBKJ_00433 1.3e-134 K Transcriptional regulator
KNIFDBKJ_00434 9.7e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KNIFDBKJ_00435 1.8e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KNIFDBKJ_00436 1.5e-190 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KNIFDBKJ_00437 4.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KNIFDBKJ_00438 2.9e-203 pyrP F Permease
KNIFDBKJ_00439 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KNIFDBKJ_00440 9.6e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KNIFDBKJ_00441 2.3e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KNIFDBKJ_00442 2.5e-56 3.1.3.18 J HAD-hyrolase-like
KNIFDBKJ_00443 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KNIFDBKJ_00444 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KNIFDBKJ_00445 2.2e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KNIFDBKJ_00446 1.5e-118 prmA J Ribosomal protein L11 methyltransferase
KNIFDBKJ_00447 3.8e-42 XK27_03960 S Protein of unknown function (DUF3013)
KNIFDBKJ_00448 3.9e-144 iunH2 3.2.2.1 F nucleoside hydrolase
KNIFDBKJ_00449 6.4e-12
KNIFDBKJ_00450 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KNIFDBKJ_00451 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
KNIFDBKJ_00452 1.2e-128 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KNIFDBKJ_00453 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KNIFDBKJ_00454 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KNIFDBKJ_00455 6.9e-43 yodB K Transcriptional regulator, HxlR family
KNIFDBKJ_00456 3.6e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KNIFDBKJ_00457 1.7e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNIFDBKJ_00460 1.7e-15
KNIFDBKJ_00462 1.2e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KNIFDBKJ_00463 7.1e-44 S Repeat protein
KNIFDBKJ_00464 1.8e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KNIFDBKJ_00465 8.7e-31 tnp L Transposase IS66 family
KNIFDBKJ_00466 1.7e-32 P Heavy-metal-associated domain
KNIFDBKJ_00467 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
KNIFDBKJ_00468 1.3e-20 L PFAM transposase IS3 IS911 family protein
KNIFDBKJ_00469 1.4e-41 L Integrase core domain
KNIFDBKJ_00470 2.4e-35 L Integrase core domain
KNIFDBKJ_00471 5.8e-129 EGP Major Facilitator Superfamily
KNIFDBKJ_00472 4.1e-98 EGP Major Facilitator Superfamily
KNIFDBKJ_00473 3.7e-72 K Transcriptional regulator, LysR family
KNIFDBKJ_00474 4.7e-138 G Xylose isomerase-like TIM barrel
KNIFDBKJ_00475 5e-116 IQ Enoyl-(Acyl carrier protein) reductase
KNIFDBKJ_00476 3.6e-217 1.3.5.4 C FAD binding domain
KNIFDBKJ_00477 8.4e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KNIFDBKJ_00478 2.2e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KNIFDBKJ_00479 1.1e-142 xerS L Phage integrase family
KNIFDBKJ_00480 1.4e-32 S Domain of unknown function (DUF4417)
KNIFDBKJ_00485 2.1e-102 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KNIFDBKJ_00486 8.2e-13 ptp3 3.1.3.48 T Tyrosine phosphatase family
KNIFDBKJ_00487 8.7e-39 ptp3 3.1.3.48 T Tyrosine phosphatase family
KNIFDBKJ_00488 2.4e-75 desR K helix_turn_helix, Lux Regulon
KNIFDBKJ_00489 5.4e-57 salK 2.7.13.3 T Histidine kinase
KNIFDBKJ_00490 1.9e-53 yvfS V ABC-2 type transporter
KNIFDBKJ_00491 5.2e-79 yvfR V ABC transporter
KNIFDBKJ_00492 1.6e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KNIFDBKJ_00493 1.7e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KNIFDBKJ_00494 2.7e-30
KNIFDBKJ_00495 4.8e-61 sip L Belongs to the 'phage' integrase family
KNIFDBKJ_00496 6.5e-07
KNIFDBKJ_00499 5e-30 M CHAP domain
KNIFDBKJ_00501 7.7e-192 U type IV secretory pathway VirB4
KNIFDBKJ_00502 1.6e-27
KNIFDBKJ_00504 6.5e-77
KNIFDBKJ_00505 2.2e-219 U TraM recognition site of TraD and TraG
KNIFDBKJ_00509 2.2e-148 clpB O Belongs to the ClpA ClpB family
KNIFDBKJ_00512 1.5e-167 topA2 5.99.1.2 G Topoisomerase IA
KNIFDBKJ_00513 1e-42 L Protein of unknown function (DUF3991)
KNIFDBKJ_00514 2.9e-68
KNIFDBKJ_00516 2.1e-59 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
KNIFDBKJ_00517 1.1e-212 V N-6 DNA Methylase
KNIFDBKJ_00518 3.5e-22 S PIN domain
KNIFDBKJ_00519 2.6e-11 D Antitoxin component of a toxin-antitoxin (TA) module
KNIFDBKJ_00521 2.5e-91 pac DM Glucan-binding protein C
KNIFDBKJ_00524 6.1e-07
KNIFDBKJ_00525 3.9e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KNIFDBKJ_00526 1.7e-54 rplI J Binds to the 23S rRNA
KNIFDBKJ_00527 3.6e-207 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KNIFDBKJ_00528 4e-64 C FMN binding
KNIFDBKJ_00529 9.6e-231 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KNIFDBKJ_00531 1.5e-156 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KNIFDBKJ_00532 1.6e-59 ykhA 3.1.2.20 I Thioesterase superfamily
KNIFDBKJ_00533 1.9e-10 S CAAX protease self-immunity
KNIFDBKJ_00534 2.5e-82 S Belongs to the UPF0246 family
KNIFDBKJ_00535 3.5e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KNIFDBKJ_00536 1.1e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
KNIFDBKJ_00537 4.9e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KNIFDBKJ_00538 5.3e-197 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
KNIFDBKJ_00539 7.1e-160 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
KNIFDBKJ_00540 1.7e-56 3.1.3.48 K Transcriptional regulator
KNIFDBKJ_00541 9e-198 1.3.5.4 C FMN_bind
KNIFDBKJ_00542 4.9e-24 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
KNIFDBKJ_00543 1.2e-83 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
KNIFDBKJ_00544 9.9e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
KNIFDBKJ_00545 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KNIFDBKJ_00546 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KNIFDBKJ_00547 5.8e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
KNIFDBKJ_00548 7.8e-90 G PTS system sorbose-specific iic component
KNIFDBKJ_00549 7.1e-123 G PTS system mannose/fructose/sorbose family IID component
KNIFDBKJ_00550 7.5e-39 2.7.1.191 G PTS system fructose IIA component
KNIFDBKJ_00551 4.2e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
KNIFDBKJ_00552 1.8e-112 lacI3 K helix_turn _helix lactose operon repressor
KNIFDBKJ_00553 2.8e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
KNIFDBKJ_00554 5e-77 hchA S intracellular protease amidase
KNIFDBKJ_00555 1.2e-21 K transcriptional regulator
KNIFDBKJ_00556 2.8e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KNIFDBKJ_00557 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KNIFDBKJ_00558 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KNIFDBKJ_00559 2.1e-250 ctpA 3.6.3.54 P P-type ATPase
KNIFDBKJ_00560 1.4e-65 pgm3 G phosphoglycerate mutase family
KNIFDBKJ_00561 3.9e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
KNIFDBKJ_00562 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KNIFDBKJ_00563 2.3e-217 yifK E Amino acid permease
KNIFDBKJ_00564 1.1e-202 oppA E ABC transporter, substratebinding protein
KNIFDBKJ_00565 4.6e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNIFDBKJ_00566 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNIFDBKJ_00567 1.3e-180 oppD P Belongs to the ABC transporter superfamily
KNIFDBKJ_00568 2.2e-155 oppF P Belongs to the ABC transporter superfamily
KNIFDBKJ_00569 9.2e-16 psiE S Phosphate-starvation-inducible E
KNIFDBKJ_00570 2.4e-208 mmuP E amino acid
KNIFDBKJ_00571 9e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KNIFDBKJ_00572 4.5e-39 K LytTr DNA-binding domain
KNIFDBKJ_00573 6.6e-17 S Protein of unknown function (DUF3021)
KNIFDBKJ_00574 1.2e-150 yfeX P Peroxidase
KNIFDBKJ_00575 3e-30 tetR K Transcriptional regulator C-terminal region
KNIFDBKJ_00576 4.1e-47 S Short repeat of unknown function (DUF308)
KNIFDBKJ_00577 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KNIFDBKJ_00578 6.2e-163 oxlT P Major Facilitator Superfamily
KNIFDBKJ_00579 1.2e-67 ybbL S ABC transporter
KNIFDBKJ_00580 1e-32 ybbM S Uncharacterised protein family (UPF0014)
KNIFDBKJ_00581 4e-59 ybbM S Uncharacterised protein family (UPF0014)
KNIFDBKJ_00582 4.2e-43 ytcD K HxlR-like helix-turn-helix
KNIFDBKJ_00583 8.4e-119 ytbE S reductase
KNIFDBKJ_00584 9.8e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KNIFDBKJ_00585 7e-217 yeeA V Type II restriction enzyme, methylase subunits
KNIFDBKJ_00586 6.9e-257 yeeB L DEAD-like helicases superfamily
KNIFDBKJ_00587 7.4e-92 pstS P T5orf172
KNIFDBKJ_00588 6.9e-15
KNIFDBKJ_00589 4.6e-24
KNIFDBKJ_00592 1.3e-161 potE2 E amino acid
KNIFDBKJ_00593 1.1e-145 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KNIFDBKJ_00594 2.7e-116 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KNIFDBKJ_00595 1.9e-57 racA K Domain of unknown function (DUF1836)
KNIFDBKJ_00596 3.5e-80 yitS S EDD domain protein, DegV family
KNIFDBKJ_00597 1.1e-45 yjaB_1 K Acetyltransferase (GNAT) domain
KNIFDBKJ_00598 3.4e-07
KNIFDBKJ_00599 3.1e-286 hsdR 3.1.21.3 L DEAD/DEAH box helicase
KNIFDBKJ_00600 4e-225 hsdM 2.1.1.72 V type I restriction-modification system
KNIFDBKJ_00601 8.6e-90 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
KNIFDBKJ_00602 4.1e-67
KNIFDBKJ_00603 2.1e-117 O AAA domain (Cdc48 subfamily)
KNIFDBKJ_00604 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KNIFDBKJ_00605 0.0 O Belongs to the peptidase S8 family
KNIFDBKJ_00606 1.6e-26 S protein encoded in hypervariable junctions of pilus gene clusters
KNIFDBKJ_00607 9e-102 qmcA O prohibitin homologues
KNIFDBKJ_00608 9.3e-62 L Resolvase, N-terminal domain
KNIFDBKJ_00609 2.2e-100 L Probable transposase
KNIFDBKJ_00610 1.8e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
KNIFDBKJ_00611 6.2e-57 tlpA2 L Transposase IS200 like
KNIFDBKJ_00612 5.3e-157 L transposase, IS605 OrfB family
KNIFDBKJ_00613 2.2e-86 dps P Ferritin-like domain
KNIFDBKJ_00614 4.3e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
KNIFDBKJ_00615 1.4e-42 L hmm pf00665
KNIFDBKJ_00616 1.7e-19 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
KNIFDBKJ_00617 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KNIFDBKJ_00618 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
KNIFDBKJ_00619 9e-181 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KNIFDBKJ_00620 1.5e-229 lpdA 1.8.1.4 C Dehydrogenase
KNIFDBKJ_00621 1.2e-148 lplA 6.3.1.20 H Lipoate-protein ligase
KNIFDBKJ_00622 9.2e-56 S Protein of unknown function (DUF975)
KNIFDBKJ_00623 1.4e-76 E GDSL-like Lipase/Acylhydrolase family
KNIFDBKJ_00624 8.9e-38
KNIFDBKJ_00625 4.1e-27 gcvR T Belongs to the UPF0237 family
KNIFDBKJ_00626 3e-219 XK27_08635 S UPF0210 protein
KNIFDBKJ_00627 2.2e-86 fruR K DeoR C terminal sensor domain
KNIFDBKJ_00628 4.5e-150 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KNIFDBKJ_00629 2.3e-300 fruA 2.7.1.202 GT Phosphotransferase System
KNIFDBKJ_00630 2e-49 cps3F
KNIFDBKJ_00631 6e-83 S Membrane
KNIFDBKJ_00632 1.8e-254 E Amino acid permease
KNIFDBKJ_00633 3.5e-231 cadA P P-type ATPase
KNIFDBKJ_00634 1.9e-113 degV S EDD domain protein, DegV family
KNIFDBKJ_00635 9.6e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KNIFDBKJ_00636 4.7e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
KNIFDBKJ_00637 7.2e-27 ydiI Q Thioesterase superfamily
KNIFDBKJ_00638 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KNIFDBKJ_00639 7.8e-141 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KNIFDBKJ_00640 5.6e-82 S L,D-transpeptidase catalytic domain
KNIFDBKJ_00641 1.3e-164 EGP Major facilitator Superfamily
KNIFDBKJ_00642 7.5e-20 K helix_turn_helix multiple antibiotic resistance protein
KNIFDBKJ_00643 1.7e-225 pipD E Dipeptidase
KNIFDBKJ_00644 4.3e-123 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KNIFDBKJ_00645 2.6e-32 ywjH S Protein of unknown function (DUF1634)
KNIFDBKJ_00646 1.7e-119 yxaA S membrane transporter protein
KNIFDBKJ_00647 4.5e-83 lysR5 K LysR substrate binding domain
KNIFDBKJ_00648 9.4e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
KNIFDBKJ_00649 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNIFDBKJ_00650 1.6e-270 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KNIFDBKJ_00651 6.8e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
KNIFDBKJ_00652 5.5e-243 lysP E amino acid
KNIFDBKJ_00653 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KNIFDBKJ_00654 1.8e-155 amtB P ammonium transporter
KNIFDBKJ_00655 3.7e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KNIFDBKJ_00656 6.6e-46 argR K Regulates arginine biosynthesis genes
KNIFDBKJ_00657 1e-132 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
KNIFDBKJ_00658 5.7e-91 S Alpha/beta hydrolase of unknown function (DUF915)
KNIFDBKJ_00659 1.2e-22 veg S Biofilm formation stimulator VEG
KNIFDBKJ_00660 1.4e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KNIFDBKJ_00661 1.3e-86 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KNIFDBKJ_00662 1.7e-102 tatD L hydrolase, TatD family
KNIFDBKJ_00663 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KNIFDBKJ_00664 5.6e-127
KNIFDBKJ_00665 1.8e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KNIFDBKJ_00666 4.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
KNIFDBKJ_00667 3.9e-31 K Transcriptional regulator
KNIFDBKJ_00668 2.4e-105 ybhR V ABC transporter
KNIFDBKJ_00669 7.1e-82 ybhF_2 V abc transporter atp-binding protein
KNIFDBKJ_00670 5.5e-103 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KNIFDBKJ_00671 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KNIFDBKJ_00672 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KNIFDBKJ_00673 1.4e-269 helD 3.6.4.12 L DNA helicase
KNIFDBKJ_00675 1.4e-108 htpX O Belongs to the peptidase M48B family
KNIFDBKJ_00676 3e-72 lemA S LemA family
KNIFDBKJ_00677 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
KNIFDBKJ_00678 1.1e-45 yjcF K protein acetylation
KNIFDBKJ_00680 3.3e-253 yfiC V ABC transporter
KNIFDBKJ_00681 1.3e-222 lmrA V ABC transporter, ATP-binding protein
KNIFDBKJ_00682 1.1e-33 K Bacterial regulatory proteins, tetR family
KNIFDBKJ_00683 1.5e-243 yhcA V ABC transporter, ATP-binding protein
KNIFDBKJ_00684 2.9e-222 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KNIFDBKJ_00685 5.1e-146 G Transporter, major facilitator family protein
KNIFDBKJ_00686 2.5e-89 lacX 5.1.3.3 G Aldose 1-epimerase
KNIFDBKJ_00687 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
KNIFDBKJ_00688 1.4e-111 K response regulator
KNIFDBKJ_00689 6.8e-90 patB 4.4.1.8 E Aminotransferase, class I
KNIFDBKJ_00690 9e-93 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KNIFDBKJ_00694 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
KNIFDBKJ_00695 5.4e-48 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KNIFDBKJ_00696 6.6e-69 coiA 3.6.4.12 S Competence protein
KNIFDBKJ_00697 1.2e-229 pepF E oligoendopeptidase F
KNIFDBKJ_00698 2.3e-41 yjbH Q Thioredoxin
KNIFDBKJ_00699 1.9e-97 pstS P Phosphate
KNIFDBKJ_00700 6e-118 pstC P probably responsible for the translocation of the substrate across the membrane
KNIFDBKJ_00701 3.9e-122 pstA P Phosphate transport system permease protein PstA
KNIFDBKJ_00702 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KNIFDBKJ_00703 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KNIFDBKJ_00704 3.6e-56 P Plays a role in the regulation of phosphate uptake
KNIFDBKJ_00705 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KNIFDBKJ_00706 1.1e-79 S VIT family
KNIFDBKJ_00707 4.2e-84 S membrane
KNIFDBKJ_00708 1.1e-39 M1-874 K Domain of unknown function (DUF1836)
KNIFDBKJ_00709 1.8e-65 hly S protein, hemolysin III
KNIFDBKJ_00710 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
KNIFDBKJ_00711 1.3e-74 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KNIFDBKJ_00714 5.1e-14
KNIFDBKJ_00715 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KNIFDBKJ_00716 1.1e-157 ccpA K catabolite control protein A
KNIFDBKJ_00717 1.1e-41 S VanZ like family
KNIFDBKJ_00718 1.5e-119 yebC K Transcriptional regulatory protein
KNIFDBKJ_00719 2.3e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNIFDBKJ_00720 1.1e-120 comGA NU Type II IV secretion system protein
KNIFDBKJ_00721 3.4e-98 comGB NU type II secretion system
KNIFDBKJ_00722 1.8e-26 comGC U competence protein ComGC
KNIFDBKJ_00723 5e-14
KNIFDBKJ_00725 1.6e-10 S Putative Competence protein ComGF
KNIFDBKJ_00727 5.8e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
KNIFDBKJ_00728 1.7e-182 cycA E Amino acid permease
KNIFDBKJ_00729 3e-57 S Calcineurin-like phosphoesterase
KNIFDBKJ_00730 1.9e-53 yutD S Protein of unknown function (DUF1027)
KNIFDBKJ_00731 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KNIFDBKJ_00732 4.6e-32 S Protein of unknown function (DUF1461)
KNIFDBKJ_00733 3e-92 dedA S SNARE associated Golgi protein
KNIFDBKJ_00734 2.3e-94 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KNIFDBKJ_00735 1.1e-49 yugI 5.3.1.9 J general stress protein
KNIFDBKJ_00736 1.9e-208 brnQ U Component of the transport system for branched-chain amino acids
KNIFDBKJ_00738 7.7e-109 endA F DNA RNA non-specific endonuclease
KNIFDBKJ_00739 1.8e-75 XK27_02070 S Nitroreductase family
KNIFDBKJ_00740 2.4e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
KNIFDBKJ_00741 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
KNIFDBKJ_00742 6.8e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
KNIFDBKJ_00743 2.7e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KNIFDBKJ_00744 1e-57 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
KNIFDBKJ_00745 5.1e-77 azlC E branched-chain amino acid
KNIFDBKJ_00746 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
KNIFDBKJ_00747 2.6e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
KNIFDBKJ_00748 1.6e-55 jag S R3H domain protein
KNIFDBKJ_00749 4.5e-53 K Transcriptional regulator C-terminal region
KNIFDBKJ_00750 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
KNIFDBKJ_00751 2e-285 pepO 3.4.24.71 O Peptidase family M13
KNIFDBKJ_00752 5e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
KNIFDBKJ_00753 2.1e-07 yvaZ S SdpI/YhfL protein family
KNIFDBKJ_00754 8.6e-71 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KNIFDBKJ_00755 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
KNIFDBKJ_00756 1.3e-40 wecD K Acetyltransferase GNAT Family
KNIFDBKJ_00758 1.3e-37 aguA_2 3.5.3.12 E Porphyromonas-type peptidyl-arginine deiminase
KNIFDBKJ_00759 6.3e-85 XK27_06780 V ABC transporter permease
KNIFDBKJ_00760 3.4e-148 XK27_06780 V ABC transporter permease
KNIFDBKJ_00761 7.1e-95 XK27_06785 V ABC transporter, ATP-binding protein
KNIFDBKJ_00762 3.2e-34 tetR K transcriptional regulator
KNIFDBKJ_00763 1.4e-18
KNIFDBKJ_00767 5.4e-22
KNIFDBKJ_00768 4.1e-87 L HNH nucleases
KNIFDBKJ_00769 4e-78 L Phage terminase, small subunit
KNIFDBKJ_00770 0.0 S Phage Terminase
KNIFDBKJ_00772 5.7e-198 S Phage portal protein
KNIFDBKJ_00773 1e-112 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
KNIFDBKJ_00774 4.5e-198 S Phage capsid family
KNIFDBKJ_00775 8.2e-22 S Phage gp6-like head-tail connector protein
KNIFDBKJ_00776 9.3e-59 S Phage head-tail joining protein
KNIFDBKJ_00777 5.3e-63 S Bacteriophage HK97-gp10, putative tail-component
KNIFDBKJ_00778 1e-55 S Protein of unknown function (DUF806)
KNIFDBKJ_00779 4.6e-78 S Phage tail tube protein
KNIFDBKJ_00780 9.8e-17 S Phage tail assembly chaperone proteins, TAC
KNIFDBKJ_00782 2.4e-306 M Phage tail tape measure protein TP901
KNIFDBKJ_00783 4.6e-77 S Phage tail protein
KNIFDBKJ_00784 7.5e-117 rny D peptidase
KNIFDBKJ_00786 6.1e-24 S Calcineurin-like phosphoesterase
KNIFDBKJ_00787 1.8e-20
KNIFDBKJ_00792 4.7e-09 hol S Bacteriophage holin
KNIFDBKJ_00793 5.5e-130 lys 3.5.1.104 M and GP 10880731
KNIFDBKJ_00794 0.0 pepN 3.4.11.2 E aminopeptidase
KNIFDBKJ_00795 1.8e-43 2.7.13.3 T protein histidine kinase activity
KNIFDBKJ_00796 1.6e-22 agrA KT Response regulator of the LytR AlgR family
KNIFDBKJ_00798 1.3e-16 M domain protein
KNIFDBKJ_00804 4.4e-123 yvgN C Aldo keto reductase
KNIFDBKJ_00805 2.2e-70 K DeoR C terminal sensor domain
KNIFDBKJ_00806 2.3e-46 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KNIFDBKJ_00807 6.9e-42 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
KNIFDBKJ_00808 1.2e-216 pts36C G PTS system sugar-specific permease component
KNIFDBKJ_00810 2.3e-104 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
KNIFDBKJ_00812 5.4e-58 S COG NOG19168 non supervised orthologous group
KNIFDBKJ_00813 4.9e-190 XK27_11280 S Psort location CytoplasmicMembrane, score
KNIFDBKJ_00814 7.1e-15 L Plasmid pRiA4b ORF-3-like protein
KNIFDBKJ_00815 2.6e-105 L Belongs to the 'phage' integrase family
KNIFDBKJ_00816 5.6e-18 3.1.21.3 V Type I restriction modification DNA specificity domain
KNIFDBKJ_00817 6.6e-60 hsdM 2.1.1.72 V type I restriction-modification system
KNIFDBKJ_00819 1.5e-124 L T/G mismatch-specific endonuclease activity
KNIFDBKJ_00823 6.7e-72 csm6 S Psort location Cytoplasmic, score
KNIFDBKJ_00824 1.1e-31 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNIFDBKJ_00825 1.9e-87 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNIFDBKJ_00826 5e-70 csm5 L RAMP superfamily
KNIFDBKJ_00827 5.1e-61 csm4 L CRISPR-associated RAMP protein, Csm4 family
KNIFDBKJ_00828 9.8e-70 csm3 L RAMP superfamily
KNIFDBKJ_00829 6e-29 csm2 L Csm2 Type III-A
KNIFDBKJ_00830 2.5e-205 csm1 S CRISPR-associated protein Csm1 family
KNIFDBKJ_00831 6.5e-34 cas6 S Pfam:DUF2276
KNIFDBKJ_00832 1.5e-205 G PTS system Galactitol-specific IIC component
KNIFDBKJ_00833 1.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KNIFDBKJ_00834 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KNIFDBKJ_00835 2.8e-85 dprA LU DNA protecting protein DprA
KNIFDBKJ_00836 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KNIFDBKJ_00837 2.1e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KNIFDBKJ_00838 3.6e-24 yozE S Belongs to the UPF0346 family
KNIFDBKJ_00839 1.2e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
KNIFDBKJ_00840 2.9e-80 ypmR E GDSL-like Lipase/Acylhydrolase
KNIFDBKJ_00842 2.1e-113 S Aldo keto reductase
KNIFDBKJ_00843 2.7e-34 K helix_turn_helix, mercury resistance
KNIFDBKJ_00844 1.8e-132 yvgN C Aldo keto reductase
KNIFDBKJ_00847 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KNIFDBKJ_00848 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KNIFDBKJ_00849 2.4e-192 cycA E Amino acid permease
KNIFDBKJ_00850 2.2e-187 ytgP S Polysaccharide biosynthesis protein
KNIFDBKJ_00851 4e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KNIFDBKJ_00852 1.2e-80 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KNIFDBKJ_00853 3e-193 pepV 3.5.1.18 E dipeptidase PepV
KNIFDBKJ_00855 5.2e-36
KNIFDBKJ_00856 3.4e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KNIFDBKJ_00857 4.2e-61 marR K Transcriptional regulator, MarR family
KNIFDBKJ_00858 2.9e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNIFDBKJ_00859 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNIFDBKJ_00860 2.9e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KNIFDBKJ_00861 1.1e-98 IQ reductase
KNIFDBKJ_00862 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KNIFDBKJ_00863 4.6e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KNIFDBKJ_00864 3.9e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KNIFDBKJ_00865 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KNIFDBKJ_00866 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KNIFDBKJ_00867 4.4e-101 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KNIFDBKJ_00868 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KNIFDBKJ_00869 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KNIFDBKJ_00870 4.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
KNIFDBKJ_00871 1.3e-301 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KNIFDBKJ_00872 5.7e-119 gla U Major intrinsic protein
KNIFDBKJ_00873 1.5e-45 ykuL S CBS domain
KNIFDBKJ_00874 3.9e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KNIFDBKJ_00875 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KNIFDBKJ_00876 9e-87 ykuT M mechanosensitive ion channel
KNIFDBKJ_00878 3e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KNIFDBKJ_00879 2e-21 yheA S Belongs to the UPF0342 family
KNIFDBKJ_00880 8.6e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
KNIFDBKJ_00881 3.3e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KNIFDBKJ_00883 7e-53 hit FG histidine triad
KNIFDBKJ_00884 1.3e-94 ecsA V ABC transporter, ATP-binding protein
KNIFDBKJ_00885 6.4e-72 ecsB U ABC transporter
KNIFDBKJ_00886 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
KNIFDBKJ_00887 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KNIFDBKJ_00889 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KNIFDBKJ_00890 4e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KNIFDBKJ_00891 1.2e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
KNIFDBKJ_00892 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KNIFDBKJ_00893 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
KNIFDBKJ_00894 6.7e-69 ybhL S Belongs to the BI1 family
KNIFDBKJ_00895 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNIFDBKJ_00896 4.3e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KNIFDBKJ_00897 1.6e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KNIFDBKJ_00898 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KNIFDBKJ_00899 1.4e-78 dnaB L replication initiation and membrane attachment
KNIFDBKJ_00900 1.3e-107 dnaI L Primosomal protein DnaI
KNIFDBKJ_00901 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KNIFDBKJ_00902 2.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KNIFDBKJ_00903 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KNIFDBKJ_00904 2.2e-52 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KNIFDBKJ_00905 3e-69 yqeG S HAD phosphatase, family IIIA
KNIFDBKJ_00906 6.7e-180 yqeH S Ribosome biogenesis GTPase YqeH
KNIFDBKJ_00907 6e-30 yhbY J RNA-binding protein
KNIFDBKJ_00908 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KNIFDBKJ_00909 2.6e-69 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KNIFDBKJ_00910 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KNIFDBKJ_00911 1.5e-82 H Nodulation protein S (NodS)
KNIFDBKJ_00912 1e-122 ylbM S Belongs to the UPF0348 family
KNIFDBKJ_00913 2e-57 yceD S Uncharacterized ACR, COG1399
KNIFDBKJ_00914 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KNIFDBKJ_00915 4e-89 plsC 2.3.1.51 I Acyltransferase
KNIFDBKJ_00916 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
KNIFDBKJ_00917 1.5e-27 yazA L GIY-YIG catalytic domain protein
KNIFDBKJ_00918 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
KNIFDBKJ_00919 3e-127 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KNIFDBKJ_00920 6.9e-37
KNIFDBKJ_00921 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KNIFDBKJ_00922 1.4e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KNIFDBKJ_00923 9.3e-158 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KNIFDBKJ_00924 3.5e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KNIFDBKJ_00925 6.6e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KNIFDBKJ_00927 3.1e-111 K response regulator
KNIFDBKJ_00928 3.9e-167 arlS 2.7.13.3 T Histidine kinase
KNIFDBKJ_00929 5.1e-117 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KNIFDBKJ_00930 1.6e-23 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KNIFDBKJ_00931 1.4e-135 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KNIFDBKJ_00932 7.3e-105
KNIFDBKJ_00933 5.5e-117
KNIFDBKJ_00934 1.3e-41 dut S dUTPase
KNIFDBKJ_00935 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KNIFDBKJ_00936 3.7e-46 yqhY S Asp23 family, cell envelope-related function
KNIFDBKJ_00937 5.5e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KNIFDBKJ_00938 1e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KNIFDBKJ_00939 3.8e-145 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KNIFDBKJ_00940 9.6e-17 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KNIFDBKJ_00941 1.6e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KNIFDBKJ_00942 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KNIFDBKJ_00943 6.6e-49 argR K Regulates arginine biosynthesis genes
KNIFDBKJ_00944 8.7e-176 recN L May be involved in recombinational repair of damaged DNA
KNIFDBKJ_00945 2.7e-82 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KNIFDBKJ_00946 6.5e-30 ynzC S UPF0291 protein
KNIFDBKJ_00947 2.9e-26 yneF S UPF0154 protein
KNIFDBKJ_00948 1.6e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
KNIFDBKJ_00949 2.1e-43 MA20_27270 S mazG nucleotide pyrophosphohydrolase
KNIFDBKJ_00950 1.9e-75 yciQ P membrane protein (DUF2207)
KNIFDBKJ_00951 1.7e-19 D nuclear chromosome segregation
KNIFDBKJ_00952 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KNIFDBKJ_00953 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KNIFDBKJ_00954 2.4e-68 gluP 3.4.21.105 S Peptidase, S54 family
KNIFDBKJ_00955 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
KNIFDBKJ_00956 6.2e-158 glk 2.7.1.2 G Glucokinase
KNIFDBKJ_00957 2.7e-46 yqhL P Rhodanese-like protein
KNIFDBKJ_00958 1.9e-15 WQ51_02665 S Protein of unknown function (DUF3042)
KNIFDBKJ_00959 2.7e-110 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KNIFDBKJ_00960 3.6e-206 ynbB 4.4.1.1 P aluminum resistance
KNIFDBKJ_00961 6.2e-45 glnR K Transcriptional regulator
KNIFDBKJ_00962 2e-247 glnA 6.3.1.2 E glutamine synthetase
KNIFDBKJ_00964 4.4e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KNIFDBKJ_00965 2.7e-48 S Domain of unknown function (DUF956)
KNIFDBKJ_00966 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KNIFDBKJ_00967 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KNIFDBKJ_00968 1.7e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KNIFDBKJ_00969 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
KNIFDBKJ_00970 5.3e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KNIFDBKJ_00971 1e-259 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KNIFDBKJ_00972 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNIFDBKJ_00973 8e-66 rimP J Required for maturation of 30S ribosomal subunits
KNIFDBKJ_00974 3.7e-170 nusA K Participates in both transcription termination and antitermination
KNIFDBKJ_00975 1.2e-38 ylxR K Protein of unknown function (DUF448)
KNIFDBKJ_00976 3.4e-25 ylxQ J ribosomal protein
KNIFDBKJ_00977 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KNIFDBKJ_00978 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KNIFDBKJ_00979 3.1e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KNIFDBKJ_00980 1.1e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KNIFDBKJ_00981 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KNIFDBKJ_00982 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KNIFDBKJ_00983 1.5e-274 dnaK O Heat shock 70 kDa protein
KNIFDBKJ_00984 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KNIFDBKJ_00985 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KNIFDBKJ_00987 4.6e-205 glnP P ABC transporter
KNIFDBKJ_00988 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KNIFDBKJ_00989 1.5e-31
KNIFDBKJ_00990 2e-111 ampC V Beta-lactamase
KNIFDBKJ_00991 3.5e-110 cobQ S glutamine amidotransferase
KNIFDBKJ_00992 3e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
KNIFDBKJ_00993 6.8e-86 tdk 2.7.1.21 F thymidine kinase
KNIFDBKJ_00994 1.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KNIFDBKJ_00995 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KNIFDBKJ_00996 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KNIFDBKJ_00997 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KNIFDBKJ_00998 2.6e-97 atpB C it plays a direct role in the translocation of protons across the membrane
KNIFDBKJ_00999 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KNIFDBKJ_01000 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KNIFDBKJ_01001 7e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KNIFDBKJ_01002 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KNIFDBKJ_01003 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KNIFDBKJ_01004 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KNIFDBKJ_01005 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KNIFDBKJ_01006 4.1e-15 ywzB S Protein of unknown function (DUF1146)
KNIFDBKJ_01007 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNIFDBKJ_01008 1.3e-166 mbl D Cell shape determining protein MreB Mrl
KNIFDBKJ_01009 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KNIFDBKJ_01010 1.3e-13 S Protein of unknown function (DUF2969)
KNIFDBKJ_01011 1.8e-186 rodA D Belongs to the SEDS family
KNIFDBKJ_01012 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
KNIFDBKJ_01013 1.9e-94 2.7.1.89 M Phosphotransferase enzyme family
KNIFDBKJ_01014 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KNIFDBKJ_01015 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KNIFDBKJ_01016 7.5e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KNIFDBKJ_01017 1.9e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KNIFDBKJ_01018 1.5e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KNIFDBKJ_01019 2e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KNIFDBKJ_01020 1.9e-90 stp 3.1.3.16 T phosphatase
KNIFDBKJ_01021 1.8e-192 KLT serine threonine protein kinase
KNIFDBKJ_01022 8.4e-109 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KNIFDBKJ_01023 4.5e-59 thiN 2.7.6.2 H thiamine pyrophosphokinase
KNIFDBKJ_01024 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KNIFDBKJ_01025 4.5e-53 asp S Asp23 family, cell envelope-related function
KNIFDBKJ_01026 3.3e-239 yloV S DAK2 domain fusion protein YloV
KNIFDBKJ_01027 1.3e-245 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KNIFDBKJ_01028 1.8e-139 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KNIFDBKJ_01029 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNIFDBKJ_01030 3.9e-101 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KNIFDBKJ_01031 2.3e-210 smc D Required for chromosome condensation and partitioning
KNIFDBKJ_01032 5.5e-146 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KNIFDBKJ_01033 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KNIFDBKJ_01034 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KNIFDBKJ_01035 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KNIFDBKJ_01036 1.1e-26 ylqC S Belongs to the UPF0109 family
KNIFDBKJ_01037 2.5e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KNIFDBKJ_01038 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KNIFDBKJ_01039 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
KNIFDBKJ_01040 9.1e-198 yfnA E amino acid
KNIFDBKJ_01041 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KNIFDBKJ_01042 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
KNIFDBKJ_01043 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KNIFDBKJ_01044 6.9e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KNIFDBKJ_01045 5.4e-266 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNIFDBKJ_01046 1.6e-22 S Tetratricopeptide repeat
KNIFDBKJ_01047 8e-216 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KNIFDBKJ_01048 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KNIFDBKJ_01049 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KNIFDBKJ_01050 9.5e-248 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KNIFDBKJ_01051 2.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNIFDBKJ_01052 5e-23 ykzG S Belongs to the UPF0356 family
KNIFDBKJ_01053 5.5e-25
KNIFDBKJ_01054 6.3e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KNIFDBKJ_01055 4.1e-31 1.1.1.27 C L-malate dehydrogenase activity
KNIFDBKJ_01056 1.5e-24 yktA S Belongs to the UPF0223 family
KNIFDBKJ_01057 2.2e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KNIFDBKJ_01058 0.0 typA T GTP-binding protein TypA
KNIFDBKJ_01059 1.6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
KNIFDBKJ_01060 3.2e-115 manY G PTS system
KNIFDBKJ_01061 3.6e-147 manN G system, mannose fructose sorbose family IID component
KNIFDBKJ_01062 2.3e-101 ftsW D Belongs to the SEDS family
KNIFDBKJ_01063 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KNIFDBKJ_01064 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
KNIFDBKJ_01065 8e-73 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KNIFDBKJ_01066 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KNIFDBKJ_01067 2.4e-131 ylbL T Belongs to the peptidase S16 family
KNIFDBKJ_01068 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KNIFDBKJ_01069 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNIFDBKJ_01070 1.2e-102 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNIFDBKJ_01071 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNIFDBKJ_01072 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KNIFDBKJ_01073 2e-138 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KNIFDBKJ_01074 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KNIFDBKJ_01075 1.4e-233 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KNIFDBKJ_01076 1.4e-162 purD 6.3.4.13 F Belongs to the GARS family
KNIFDBKJ_01077 2.2e-108 S Acyltransferase family
KNIFDBKJ_01078 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNIFDBKJ_01079 3e-122 K LysR substrate binding domain
KNIFDBKJ_01081 2.9e-20
KNIFDBKJ_01082 4e-58 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KNIFDBKJ_01083 4.2e-266 argS 6.1.1.19 J Arginyl-tRNA synthetase
KNIFDBKJ_01084 1.5e-49 comEA L Competence protein ComEA
KNIFDBKJ_01085 2e-69 comEB 3.5.4.12 F ComE operon protein 2
KNIFDBKJ_01086 9.4e-157 comEC S Competence protein ComEC
KNIFDBKJ_01087 6e-103 holA 2.7.7.7 L DNA polymerase III delta subunit
KNIFDBKJ_01088 3.3e-112 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KNIFDBKJ_01089 9.6e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KNIFDBKJ_01090 3.7e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KNIFDBKJ_01091 4e-93 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KNIFDBKJ_01092 3.1e-226 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KNIFDBKJ_01093 1.9e-33 ypmB S Protein conserved in bacteria
KNIFDBKJ_01094 5.8e-142 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KNIFDBKJ_01095 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KNIFDBKJ_01096 8.5e-56 dnaD L DnaD domain protein
KNIFDBKJ_01097 1.7e-82 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KNIFDBKJ_01098 7.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNIFDBKJ_01099 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNIFDBKJ_01100 1.4e-91 M transferase activity, transferring glycosyl groups
KNIFDBKJ_01101 8e-87 M Glycosyltransferase sugar-binding region containing DXD motif
KNIFDBKJ_01102 6.8e-101 epsJ1 M Glycosyltransferase like family 2
KNIFDBKJ_01105 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KNIFDBKJ_01106 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KNIFDBKJ_01107 1.8e-56 yqeY S YqeY-like protein
KNIFDBKJ_01109 1.8e-68 xerD L Phage integrase, N-terminal SAM-like domain
KNIFDBKJ_01110 1.3e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNIFDBKJ_01111 1.4e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KNIFDBKJ_01112 1.5e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KNIFDBKJ_01113 5e-276 yfmR S ABC transporter, ATP-binding protein
KNIFDBKJ_01114 2.6e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KNIFDBKJ_01115 1.2e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KNIFDBKJ_01124 2.1e-07
KNIFDBKJ_01128 1.7e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KNIFDBKJ_01129 1.4e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KNIFDBKJ_01130 1.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KNIFDBKJ_01131 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KNIFDBKJ_01132 2.5e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KNIFDBKJ_01134 1.6e-55 ctsR K Belongs to the CtsR family
KNIFDBKJ_01135 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KNIFDBKJ_01136 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNIFDBKJ_01137 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNIFDBKJ_01138 7.6e-29 S Predicted membrane protein (DUF2335)
KNIFDBKJ_01140 3.4e-34 arpU S Phage transcriptional regulator, ArpU family
KNIFDBKJ_01156 1.1e-69
KNIFDBKJ_01157 1.6e-25
KNIFDBKJ_01160 2.8e-28 S Phage replisome organizer, N-terminal domain protein
KNIFDBKJ_01161 5.4e-53 S Putative HNHc nuclease
KNIFDBKJ_01165 1.7e-83 ps308 K AntA/AntB antirepressor
KNIFDBKJ_01166 3.8e-09 XK27_07105 K Helix-turn-helix XRE-family like proteins
KNIFDBKJ_01167 9.1e-37 K Helix-turn-helix XRE-family like proteins
KNIFDBKJ_01168 1.9e-37 E Zn peptidase
KNIFDBKJ_01170 2.3e-48 polC 2.7.7.7 L DNA polymerase III
KNIFDBKJ_01172 3.1e-09
KNIFDBKJ_01173 4.3e-106 S Protein of unknown function (DUF3644)
KNIFDBKJ_01175 2.5e-89 sip L Belongs to the 'phage' integrase family
KNIFDBKJ_01176 9.4e-149 mepA V MATE efflux family protein
KNIFDBKJ_01177 3.3e-150 lsa S ABC transporter
KNIFDBKJ_01178 1.4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KNIFDBKJ_01179 8e-110 puuD S peptidase C26
KNIFDBKJ_01180 1.4e-200 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KNIFDBKJ_01181 1.1e-25
KNIFDBKJ_01182 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
KNIFDBKJ_01183 1.1e-59 uspA T Universal stress protein family
KNIFDBKJ_01185 4.7e-210 glnP P ABC transporter
KNIFDBKJ_01186 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KNIFDBKJ_01187 1.6e-75 xerC L Belongs to the 'phage' integrase family
KNIFDBKJ_01188 2.1e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KNIFDBKJ_01189 8.4e-38 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KNIFDBKJ_01190 2.5e-58 cpsF M Oligosaccharide biosynthesis protein Alg14 like
KNIFDBKJ_01191 2e-91 rfbP M Bacterial sugar transferase
KNIFDBKJ_01192 2.7e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KNIFDBKJ_01193 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KNIFDBKJ_01194 1.6e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KNIFDBKJ_01195 4e-129 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KNIFDBKJ_01197 8.5e-201 argH 4.3.2.1 E argininosuccinate lyase
KNIFDBKJ_01198 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KNIFDBKJ_01199 3.4e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KNIFDBKJ_01200 6.4e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNIFDBKJ_01201 4.7e-103 pfoS S Phosphotransferase system, EIIC
KNIFDBKJ_01203 1.5e-23 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KNIFDBKJ_01204 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KNIFDBKJ_01205 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KNIFDBKJ_01206 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KNIFDBKJ_01209 6.9e-57 K SIR2-like domain
KNIFDBKJ_01210 9.3e-21
KNIFDBKJ_01211 1.5e-46
KNIFDBKJ_01212 3.3e-64
KNIFDBKJ_01213 1.9e-28 yeeA V Type II restriction enzyme, methylase subunits
KNIFDBKJ_01214 4.1e-18
KNIFDBKJ_01215 4e-111 K IrrE N-terminal-like domain
KNIFDBKJ_01216 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KNIFDBKJ_01217 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KNIFDBKJ_01218 3.5e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KNIFDBKJ_01219 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KNIFDBKJ_01220 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KNIFDBKJ_01221 3.6e-95 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KNIFDBKJ_01222 1.1e-40 yabR J RNA binding
KNIFDBKJ_01223 1e-21 divIC D Septum formation initiator
KNIFDBKJ_01224 3.6e-31 yabO J S4 domain protein
KNIFDBKJ_01225 3.9e-141 yabM S Polysaccharide biosynthesis protein
KNIFDBKJ_01226 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KNIFDBKJ_01227 5.5e-74 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KNIFDBKJ_01228 1.4e-157 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KNIFDBKJ_01229 2.5e-86 S (CBS) domain
KNIFDBKJ_01230 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KNIFDBKJ_01231 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KNIFDBKJ_01232 7.2e-53 perR P Belongs to the Fur family
KNIFDBKJ_01233 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
KNIFDBKJ_01234 3.5e-101 sbcC L Putative exonuclease SbcCD, C subunit
KNIFDBKJ_01235 8.9e-116 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KNIFDBKJ_01236 4.6e-36 M LysM domain protein
KNIFDBKJ_01237 2.8e-276 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KNIFDBKJ_01238 2.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KNIFDBKJ_01239 1.6e-35 ygfC K Bacterial regulatory proteins, tetR family
KNIFDBKJ_01240 9.6e-112 hrtB V ABC transporter permease
KNIFDBKJ_01241 2.3e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KNIFDBKJ_01242 0.0 helD 3.6.4.12 L DNA helicase
KNIFDBKJ_01243 1.2e-245 yjbQ P TrkA C-terminal domain protein
KNIFDBKJ_01244 1.4e-30
KNIFDBKJ_01245 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
KNIFDBKJ_01246 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KNIFDBKJ_01247 5.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KNIFDBKJ_01248 3.7e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNIFDBKJ_01249 1.5e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNIFDBKJ_01250 4e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNIFDBKJ_01251 4.8e-53 rplQ J Ribosomal protein L17
KNIFDBKJ_01252 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNIFDBKJ_01253 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KNIFDBKJ_01254 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KNIFDBKJ_01255 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KNIFDBKJ_01256 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KNIFDBKJ_01257 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KNIFDBKJ_01258 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KNIFDBKJ_01259 1e-67 rplO J Binds to the 23S rRNA
KNIFDBKJ_01260 2.1e-22 rpmD J Ribosomal protein L30
KNIFDBKJ_01261 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KNIFDBKJ_01262 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KNIFDBKJ_01263 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KNIFDBKJ_01264 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KNIFDBKJ_01265 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KNIFDBKJ_01266 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KNIFDBKJ_01267 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KNIFDBKJ_01268 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KNIFDBKJ_01269 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KNIFDBKJ_01270 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
KNIFDBKJ_01271 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KNIFDBKJ_01272 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KNIFDBKJ_01273 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KNIFDBKJ_01274 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KNIFDBKJ_01275 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KNIFDBKJ_01276 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KNIFDBKJ_01277 1e-100 rplD J Forms part of the polypeptide exit tunnel
KNIFDBKJ_01278 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KNIFDBKJ_01279 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KNIFDBKJ_01280 2.3e-165 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KNIFDBKJ_01282 3.8e-21 K Acetyltransferase (GNAT) domain
KNIFDBKJ_01283 1.1e-181 steT E amino acid
KNIFDBKJ_01284 9.6e-78 glnP P ABC transporter permease
KNIFDBKJ_01285 9.3e-86 gluC P ABC transporter permease
KNIFDBKJ_01286 4.6e-101 glnH ET ABC transporter
KNIFDBKJ_01287 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KNIFDBKJ_01288 3.9e-08
KNIFDBKJ_01289 2.9e-98
KNIFDBKJ_01291 3.2e-53 zur P Belongs to the Fur family
KNIFDBKJ_01292 6.3e-212 yfnA E Amino Acid
KNIFDBKJ_01293 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KNIFDBKJ_01294 0.0 L Helicase C-terminal domain protein
KNIFDBKJ_01295 6e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
KNIFDBKJ_01296 9.3e-181 yhdP S Transporter associated domain
KNIFDBKJ_01297 3.7e-26
KNIFDBKJ_01298 1.8e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KNIFDBKJ_01299 1.6e-131 bacI V MacB-like periplasmic core domain
KNIFDBKJ_01300 3.3e-97 V ABC transporter
KNIFDBKJ_01301 3.4e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KNIFDBKJ_01302 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
KNIFDBKJ_01303 1.6e-140 V MatE
KNIFDBKJ_01304 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KNIFDBKJ_01305 6.6e-87 S Alpha beta hydrolase
KNIFDBKJ_01306 4.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KNIFDBKJ_01307 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KNIFDBKJ_01308 1.3e-111 argE 3.5.1.18 E Peptidase dimerisation domain
KNIFDBKJ_01309 1.4e-101 IQ Enoyl-(Acyl carrier protein) reductase
KNIFDBKJ_01310 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
KNIFDBKJ_01311 4.3e-54 queT S QueT transporter
KNIFDBKJ_01313 4.3e-65 degV S Uncharacterised protein, DegV family COG1307
KNIFDBKJ_01314 8.8e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KNIFDBKJ_01315 3.5e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KNIFDBKJ_01316 1.9e-34 trxA O Belongs to the thioredoxin family
KNIFDBKJ_01317 3.8e-87 S Sucrose-6F-phosphate phosphohydrolase
KNIFDBKJ_01318 2.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KNIFDBKJ_01319 1.3e-49 S Threonine/Serine exporter, ThrE
KNIFDBKJ_01320 4.8e-81 thrE S Putative threonine/serine exporter
KNIFDBKJ_01321 3.1e-27 cspC K Cold shock protein
KNIFDBKJ_01322 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
KNIFDBKJ_01323 3.1e-95 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KNIFDBKJ_01324 3.1e-23
KNIFDBKJ_01325 2.1e-58 3.6.1.27 I phosphatase
KNIFDBKJ_01326 2.2e-25
KNIFDBKJ_01327 2.1e-66 I alpha/beta hydrolase fold
KNIFDBKJ_01328 1.3e-38 azlD S branched-chain amino acid
KNIFDBKJ_01329 1.9e-104 azlC E AzlC protein
KNIFDBKJ_01330 3.5e-17
KNIFDBKJ_01331 4.9e-119 xth 3.1.11.2 L exodeoxyribonuclease III
KNIFDBKJ_01332 9.2e-91 V domain protein
KNIFDBKJ_01337 8.1e-09 S zinc-ribbon domain
KNIFDBKJ_01339 4e-11 S Mor transcription activator family
KNIFDBKJ_01340 2.3e-59 yfjR K WYL domain
KNIFDBKJ_01341 4.6e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KNIFDBKJ_01342 6.4e-173 malY 4.4.1.8 E Aminotransferase, class I
KNIFDBKJ_01343 4.4e-117 K AI-2E family transporter
KNIFDBKJ_01344 5.8e-60 EG EamA-like transporter family
KNIFDBKJ_01345 4.4e-75 L haloacid dehalogenase-like hydrolase
KNIFDBKJ_01346 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KNIFDBKJ_01347 5e-67 1.5.1.38 S NADPH-dependent FMN reductase
KNIFDBKJ_01348 3.2e-163 C Luciferase-like monooxygenase
KNIFDBKJ_01349 1.3e-41 K Transcriptional regulator, HxlR family
KNIFDBKJ_01350 5e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KNIFDBKJ_01351 3.4e-103 ydhQ K UbiC transcription regulator-associated domain protein
KNIFDBKJ_01352 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KNIFDBKJ_01353 9.2e-82 pncA Q isochorismatase
KNIFDBKJ_01354 4.6e-63 3.1.3.73 G phosphoglycerate mutase
KNIFDBKJ_01355 9.5e-259 treB G phosphotransferase system
KNIFDBKJ_01356 2.2e-83 treR K UTRA
KNIFDBKJ_01357 2.2e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
KNIFDBKJ_01358 1.4e-167 mdtG EGP Major facilitator Superfamily
KNIFDBKJ_01360 2.1e-196 XK27_08315 M Sulfatase
KNIFDBKJ_01361 5.9e-56 S peptidoglycan catabolic process
KNIFDBKJ_01362 1.1e-150 M BCCT, betaine/carnitine/choline family transporter
KNIFDBKJ_01363 1.9e-84 M Nucleotidyl transferase
KNIFDBKJ_01364 6.4e-177 licA 2.7.1.89 M Choline/ethanolamine kinase
KNIFDBKJ_01365 1.2e-88 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KNIFDBKJ_01366 1.2e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KNIFDBKJ_01367 1.5e-127 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KNIFDBKJ_01368 6e-176 thrC 4.2.3.1 E Threonine synthase
KNIFDBKJ_01369 9.1e-132 S Bacterial membrane protein YfhO
KNIFDBKJ_01370 3.6e-14
KNIFDBKJ_01371 1.6e-35 S Psort location CytoplasmicMembrane, score
KNIFDBKJ_01372 6.1e-37 S Psort location CytoplasmicMembrane, score
KNIFDBKJ_01373 5e-147 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KNIFDBKJ_01374 7.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
KNIFDBKJ_01375 7e-157 XK27_09615 S reductase
KNIFDBKJ_01376 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
KNIFDBKJ_01377 5.6e-97 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KNIFDBKJ_01378 7.3e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KNIFDBKJ_01379 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KNIFDBKJ_01381 1.8e-153 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
KNIFDBKJ_01382 1.2e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
KNIFDBKJ_01383 1.1e-22 S Acyltransferase family
KNIFDBKJ_01384 1.1e-16 S Acyltransferase family
KNIFDBKJ_01385 1e-43 S Peptidase_C39 like family
KNIFDBKJ_01388 8.5e-64 M Glycosyltransferase like family 2
KNIFDBKJ_01389 2.4e-73 M LicD family
KNIFDBKJ_01390 1.1e-57 cps3F
KNIFDBKJ_01391 3.4e-93 M transferase activity, transferring glycosyl groups
KNIFDBKJ_01392 1.3e-76 waaB GT4 M Glycosyl transferases group 1
KNIFDBKJ_01393 6.9e-92 M Core-2/I-Branching enzyme
KNIFDBKJ_01394 6e-43 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KNIFDBKJ_01395 8.9e-66 rny D Peptidase family M23
KNIFDBKJ_01399 1.2e-32
KNIFDBKJ_01401 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
KNIFDBKJ_01402 8.4e-13 bglG K antiterminator
KNIFDBKJ_01403 3.2e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KNIFDBKJ_01404 8.5e-141 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KNIFDBKJ_01405 1.9e-37 S Replication initiator protein A (RepA) N-terminus
KNIFDBKJ_01406 9.4e-109 L Initiator Replication protein
KNIFDBKJ_01407 6.1e-08 yokH G regulation of fungal-type cell wall biogenesis
KNIFDBKJ_01409 6.5e-12 L PLD-like domain
KNIFDBKJ_01410 3.5e-23 L PLD-like domain
KNIFDBKJ_01411 4.7e-73 L HTH-like domain
KNIFDBKJ_01412 7.7e-30 L Helix-turn-helix domain
KNIFDBKJ_01413 1.8e-106 L PLD-like domain
KNIFDBKJ_01415 1.3e-10 tcdC
KNIFDBKJ_01417 2.6e-232 tetP J elongation factor G
KNIFDBKJ_01418 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KNIFDBKJ_01420 4.5e-216 yjeM E Amino Acid
KNIFDBKJ_01421 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
KNIFDBKJ_01422 4.3e-75 K Helix-turn-helix domain, rpiR family
KNIFDBKJ_01423 2.5e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KNIFDBKJ_01424 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
KNIFDBKJ_01425 6.5e-90 nanK GK ROK family
KNIFDBKJ_01426 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
KNIFDBKJ_01427 4e-64 G Xylose isomerase domain protein TIM barrel
KNIFDBKJ_01428 1.3e-152 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KNIFDBKJ_01429 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNIFDBKJ_01430 1.1e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KNIFDBKJ_01431 3.6e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KNIFDBKJ_01432 7.7e-41 S Iron-sulfur cluster assembly protein
KNIFDBKJ_01433 1.3e-66 S Protein of unknown function (DUF1440)
KNIFDBKJ_01434 1.7e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
KNIFDBKJ_01435 5.9e-187 mtnE 2.6.1.83 E Aminotransferase
KNIFDBKJ_01437 7.9e-15
KNIFDBKJ_01438 1e-87 S Haloacid dehalogenase-like hydrolase
KNIFDBKJ_01441 2.9e-71 xerD L Phage integrase, N-terminal SAM-like domain
KNIFDBKJ_01442 9.7e-267 fbp 3.1.3.11 G phosphatase activity
KNIFDBKJ_01443 1.5e-186 tonB M YSIRK type signal peptide
KNIFDBKJ_01444 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KNIFDBKJ_01445 2e-97 fabK 1.3.1.9 S Nitronate monooxygenase
KNIFDBKJ_01446 9.7e-161 ytbD EGP Major facilitator Superfamily
KNIFDBKJ_01447 2.6e-55 tlpA2 L Transposase IS200 like
KNIFDBKJ_01448 2.7e-47 L Transposase, IS605 OrfB family
KNIFDBKJ_01449 1.2e-83
KNIFDBKJ_01450 1.1e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KNIFDBKJ_01452 1.4e-46 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
KNIFDBKJ_01453 1.6e-116 ddh 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNIFDBKJ_01454 3.3e-136 pfoS S Phosphotransferase system, EIIC
KNIFDBKJ_01456 1.5e-47 spaB S Lantibiotic dehydratase, C terminus
KNIFDBKJ_01457 4.2e-126 spaB S Lantibiotic dehydratase, C terminus
KNIFDBKJ_01458 7.3e-184 spaT V ATPases associated with a variety of cellular activities
KNIFDBKJ_01459 1.3e-75 spaC2 V Lanthionine synthetase C-like protein
KNIFDBKJ_01460 2.6e-89 KT Transcriptional regulatory protein, C terminal
KNIFDBKJ_01461 4.1e-104 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KNIFDBKJ_01462 1.1e-73 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
KNIFDBKJ_01463 9.6e-47 V ABC-2 family transporter protein
KNIFDBKJ_01465 2.5e-27 K Helix-turn-helix XRE-family like proteins
KNIFDBKJ_01466 5.3e-24 S protein encoded in hypervariable junctions of pilus gene clusters
KNIFDBKJ_01468 1.1e-223 E ABC transporter, substratebinding protein
KNIFDBKJ_01469 8.1e-116 sufC O FeS assembly ATPase SufC
KNIFDBKJ_01470 2.5e-143 sufD O FeS assembly protein SufD
KNIFDBKJ_01471 1.7e-147 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KNIFDBKJ_01472 1.1e-40 nifU C SUF system FeS assembly protein, NifU family
KNIFDBKJ_01473 4.2e-240 sufB O assembly protein SufB
KNIFDBKJ_01474 5.5e-45 S VIT family
KNIFDBKJ_01475 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
KNIFDBKJ_01476 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KNIFDBKJ_01477 3.6e-112 rssA S Phospholipase, patatin family
KNIFDBKJ_01478 8.2e-16
KNIFDBKJ_01480 1.1e-39
KNIFDBKJ_01483 1.3e-38 S Fic/DOC family
KNIFDBKJ_01484 8.1e-35 S Fic/DOC family
KNIFDBKJ_01485 1.6e-12 K Helix-turn-helix XRE-family like proteins
KNIFDBKJ_01486 4.5e-10
KNIFDBKJ_01488 5.3e-09 S Arc-like DNA binding domain
KNIFDBKJ_01490 5.7e-21 S Replication initiator protein A (RepA) N-terminus
KNIFDBKJ_01495 1.6e-07
KNIFDBKJ_01499 4.4e-20
KNIFDBKJ_01500 8.4e-12 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
KNIFDBKJ_01504 1.5e-42 ruvB 3.6.4.12 L four-way junction helicase activity
KNIFDBKJ_01507 8.7e-18 ps301 K PFAM helix-turn-helix domain protein
KNIFDBKJ_01511 3.7e-78 S Fic/DOC family
KNIFDBKJ_01512 4.4e-239 bcgIB 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
KNIFDBKJ_01514 1.3e-65 D nuclear chromosome segregation
KNIFDBKJ_01515 1.7e-07
KNIFDBKJ_01516 8.8e-71
KNIFDBKJ_01517 4e-148 K IrrE N-terminal-like domain
KNIFDBKJ_01518 2.6e-58 Z012_06740 S Fic/DOC family
KNIFDBKJ_01519 6.2e-106 L Belongs to the 'phage' integrase family
KNIFDBKJ_01521 3.8e-146 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KNIFDBKJ_01522 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KNIFDBKJ_01523 1.1e-278 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KNIFDBKJ_01524 3.5e-160 camS S sex pheromone
KNIFDBKJ_01525 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNIFDBKJ_01526 1.8e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KNIFDBKJ_01527 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNIFDBKJ_01528 3.4e-146 yegS 2.7.1.107 G Lipid kinase
KNIFDBKJ_01529 2.2e-209 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KNIFDBKJ_01530 1.2e-52 L Resolvase, N terminal domain
KNIFDBKJ_01531 2.1e-48 L COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
KNIFDBKJ_01532 0.0 3.1.11.5 L Psort location Cytoplasmic, score 8.87
KNIFDBKJ_01533 5.1e-24
KNIFDBKJ_01534 4.4e-34 3.1.21.3 V Type I restriction modification DNA specificity domain
KNIFDBKJ_01536 2.6e-56 S UPF0489 domain
KNIFDBKJ_01537 1.9e-121 L Mrr N-terminal domain
KNIFDBKJ_01538 1.6e-14
KNIFDBKJ_01539 5.7e-09
KNIFDBKJ_01540 3.2e-74 S Domain of unknown function (DUF4343)
KNIFDBKJ_01541 1.5e-57 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
KNIFDBKJ_01542 9e-75 S Domain of unknown function (DUF3841)
KNIFDBKJ_01543 8.1e-228 yfjM S Protein of unknown function DUF262
KNIFDBKJ_01544 2.5e-175 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
KNIFDBKJ_01545 2.8e-157 C Oxidoreductase
KNIFDBKJ_01546 1.1e-71 ywlG S Belongs to the UPF0340 family
KNIFDBKJ_01547 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KNIFDBKJ_01548 1.6e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KNIFDBKJ_01549 1.5e-57 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KNIFDBKJ_01550 1.1e-176 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
KNIFDBKJ_01551 1.5e-14 ybaN S Protein of unknown function (DUF454)
KNIFDBKJ_01552 1.3e-236 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KNIFDBKJ_01553 1.4e-198 frdC 1.3.5.4 C FAD binding domain
KNIFDBKJ_01554 1.1e-206 yflS P Sodium:sulfate symporter transmembrane region
KNIFDBKJ_01555 4.4e-18 yncA 2.3.1.79 S Maltose acetyltransferase
KNIFDBKJ_01556 8.2e-160 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KNIFDBKJ_01557 1.5e-61 dedA 3.1.3.1 S SNARE associated Golgi protein
KNIFDBKJ_01558 4.2e-95 ypuA S Protein of unknown function (DUF1002)
KNIFDBKJ_01559 2.5e-34 3.2.1.18 GH33 M Rib/alpha-like repeat
KNIFDBKJ_01560 1.5e-42 K Copper transport repressor CopY TcrY
KNIFDBKJ_01561 8e-60 T Belongs to the universal stress protein A family
KNIFDBKJ_01562 3.8e-40 K Bacterial regulatory proteins, tetR family
KNIFDBKJ_01563 3.6e-57 K transcriptional
KNIFDBKJ_01564 2.4e-71 mleR K LysR family
KNIFDBKJ_01565 5.8e-249 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
KNIFDBKJ_01566 1.6e-13 mleP S Sodium Bile acid symporter family
KNIFDBKJ_01567 1.6e-63 S ECF transporter, substrate-specific component
KNIFDBKJ_01568 1.6e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
KNIFDBKJ_01569 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KNIFDBKJ_01570 1.7e-193 pbuX F xanthine permease
KNIFDBKJ_01571 3e-37 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KNIFDBKJ_01572 9e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KNIFDBKJ_01573 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
KNIFDBKJ_01574 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KNIFDBKJ_01575 7.6e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
KNIFDBKJ_01576 3.2e-160 mgtE P Acts as a magnesium transporter
KNIFDBKJ_01578 1.7e-40
KNIFDBKJ_01579 2.2e-34 K Acetyltransferase (GNAT) domain
KNIFDBKJ_01580 3.8e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
KNIFDBKJ_01581 2.7e-136 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KNIFDBKJ_01582 3.8e-49 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
KNIFDBKJ_01583 2.2e-42 O ADP-ribosylglycohydrolase
KNIFDBKJ_01584 4.2e-221 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
KNIFDBKJ_01585 8.1e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KNIFDBKJ_01586 1.1e-156 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KNIFDBKJ_01587 3.1e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
KNIFDBKJ_01588 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
KNIFDBKJ_01589 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KNIFDBKJ_01590 1.5e-176 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
KNIFDBKJ_01591 3.4e-24 S Domain of unknown function (DUF4828)
KNIFDBKJ_01592 5.4e-128 mocA S Oxidoreductase
KNIFDBKJ_01593 3.9e-160 yfmL L DEAD DEAH box helicase
KNIFDBKJ_01594 2e-20 S Domain of unknown function (DUF3284)
KNIFDBKJ_01596 1.3e-279 kup P Transport of potassium into the cell
KNIFDBKJ_01597 1.2e-100 malR K Transcriptional regulator, LacI family
KNIFDBKJ_01598 3.8e-214 malT G Transporter, major facilitator family protein
KNIFDBKJ_01599 6.5e-78 galM 5.1.3.3 G Aldose 1-epimerase
KNIFDBKJ_01600 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KNIFDBKJ_01601 4.1e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KNIFDBKJ_01602 2.2e-264 E Amino acid permease
KNIFDBKJ_01603 1.3e-181 pepS E Thermophilic metalloprotease (M29)
KNIFDBKJ_01604 2.1e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KNIFDBKJ_01605 1.1e-70 K Sugar-specific transcriptional regulator TrmB
KNIFDBKJ_01606 6.4e-122 S Sulfite exporter TauE/SafE
KNIFDBKJ_01607 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
KNIFDBKJ_01608 0.0 S Bacterial membrane protein YfhO
KNIFDBKJ_01609 8.7e-53 gtcA S Teichoic acid glycosylation protein
KNIFDBKJ_01610 2.6e-53 fld C Flavodoxin
KNIFDBKJ_01611 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
KNIFDBKJ_01612 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KNIFDBKJ_01613 6.2e-12 mltD CBM50 M Lysin motif
KNIFDBKJ_01614 3.2e-92 yihY S Belongs to the UPF0761 family
KNIFDBKJ_01615 2.3e-147 scrR K helix_turn _helix lactose operon repressor
KNIFDBKJ_01616 9.1e-217 scrB 3.2.1.26 GH32 G invertase
KNIFDBKJ_01617 5.2e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
KNIFDBKJ_01618 7.7e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
KNIFDBKJ_01619 4.6e-114 ntpJ P Potassium uptake protein
KNIFDBKJ_01620 9.7e-59 ktrA P TrkA-N domain
KNIFDBKJ_01621 9.8e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KNIFDBKJ_01622 4e-38 M Glycosyltransferase like family 2
KNIFDBKJ_01623 1.4e-19
KNIFDBKJ_01624 1.7e-09 S Predicted membrane protein (DUF2207)
KNIFDBKJ_01625 8e-77 S Predicted membrane protein (DUF2207)
KNIFDBKJ_01626 3.3e-52 bioY S BioY family
KNIFDBKJ_01627 1.1e-282 fruA 3.2.1.1, 3.2.1.65, 3.2.1.80 GH13,GH32 GN Fructan beta-fructosidase
KNIFDBKJ_01628 2.4e-182 lmrB EGP Major facilitator Superfamily
KNIFDBKJ_01629 2.4e-93 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KNIFDBKJ_01630 8.4e-73 glcR K DeoR C terminal sensor domain
KNIFDBKJ_01631 5e-60 yceE S haloacid dehalogenase-like hydrolase
KNIFDBKJ_01632 8.2e-84 G Phosphoglycerate mutase family
KNIFDBKJ_01633 1.3e-32 S Domain of unknown function (DUF4811)
KNIFDBKJ_01634 2.7e-197 lmrB EGP Major facilitator Superfamily
KNIFDBKJ_01635 4.2e-32 merR K MerR HTH family regulatory protein
KNIFDBKJ_01636 2.3e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KNIFDBKJ_01637 7.6e-119 G Bacterial extracellular solute-binding protein
KNIFDBKJ_01638 3e-79 baeR K Bacterial regulatory proteins, luxR family
KNIFDBKJ_01639 1.2e-103 baeS T Histidine kinase
KNIFDBKJ_01640 2.6e-79 rbsB G sugar-binding domain protein
KNIFDBKJ_01641 5.3e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
KNIFDBKJ_01642 6.4e-116 manY G PTS system sorbose-specific iic component
KNIFDBKJ_01643 2.1e-147 manN G system, mannose fructose sorbose family IID component
KNIFDBKJ_01644 3.2e-52 manO S Domain of unknown function (DUF956)
KNIFDBKJ_01645 2.7e-70 mltD CBM50 M NlpC P60 family protein
KNIFDBKJ_01646 1.4e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KNIFDBKJ_01647 4.9e-165 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNIFDBKJ_01648 3.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
KNIFDBKJ_01649 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KNIFDBKJ_01650 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KNIFDBKJ_01651 7.2e-108 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNIFDBKJ_01652 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNIFDBKJ_01653 1.5e-46 S CRISPR-associated protein (Cas_Csn2)
KNIFDBKJ_01654 1.3e-38 K transcriptional regulator PadR family
KNIFDBKJ_01655 4.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
KNIFDBKJ_01656 4.1e-16 S Putative adhesin
KNIFDBKJ_01657 2.2e-16 pspC KT PspC domain
KNIFDBKJ_01659 3.9e-13 S Enterocin A Immunity
KNIFDBKJ_01660 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KNIFDBKJ_01661 2.2e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
KNIFDBKJ_01662 2.1e-99 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KNIFDBKJ_01663 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KNIFDBKJ_01664 1.5e-120 potB P ABC transporter permease
KNIFDBKJ_01665 1.7e-103 potC U Binding-protein-dependent transport system inner membrane component
KNIFDBKJ_01666 1.7e-159 potD P ABC transporter
KNIFDBKJ_01667 5.1e-131 ABC-SBP S ABC transporter
KNIFDBKJ_01668 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KNIFDBKJ_01669 3.9e-107 XK27_08845 S ABC transporter, ATP-binding protein
KNIFDBKJ_01670 4.3e-67 M ErfK YbiS YcfS YnhG
KNIFDBKJ_01671 1.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KNIFDBKJ_01672 1.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KNIFDBKJ_01673 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KNIFDBKJ_01674 1.5e-102 pgm3 G phosphoglycerate mutase
KNIFDBKJ_01675 2.7e-56 S CAAX protease self-immunity
KNIFDBKJ_01676 5.7e-48 C Flavodoxin
KNIFDBKJ_01677 1.4e-58 yphH S Cupin domain
KNIFDBKJ_01678 1e-45 yphJ 4.1.1.44 S decarboxylase
KNIFDBKJ_01679 2e-144 2.1.1.14 E methionine synthase, vitamin-B12 independent
KNIFDBKJ_01680 1.8e-108 metQ1 P Belongs to the nlpA lipoprotein family
KNIFDBKJ_01681 2.6e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KNIFDBKJ_01682 1.3e-69 metI P ABC transporter permease
KNIFDBKJ_01683 5.7e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KNIFDBKJ_01684 3e-84 drgA C nitroreductase
KNIFDBKJ_01685 4.3e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
KNIFDBKJ_01686 1e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
KNIFDBKJ_01687 8.1e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KNIFDBKJ_01688 1e-261 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
KNIFDBKJ_01690 6.2e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KNIFDBKJ_01691 2.4e-31 metI U ABC transporter permease
KNIFDBKJ_01692 8.2e-127 metQ M Belongs to the nlpA lipoprotein family
KNIFDBKJ_01693 6.3e-54 S Protein of unknown function (DUF4256)
KNIFDBKJ_01695 9.4e-95 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
KNIFDBKJ_01696 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KNIFDBKJ_01697 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
KNIFDBKJ_01698 1.3e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KNIFDBKJ_01699 1.3e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
KNIFDBKJ_01700 1.1e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KNIFDBKJ_01701 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNIFDBKJ_01702 9.7e-37 ptsH G phosphocarrier protein HPR
KNIFDBKJ_01703 1.5e-15
KNIFDBKJ_01704 0.0 clpE O Belongs to the ClpA ClpB family
KNIFDBKJ_01705 1.9e-22 XK27_09445 S Domain of unknown function (DUF1827)
KNIFDBKJ_01706 1.1e-104 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
KNIFDBKJ_01707 0.0 rafA 3.2.1.22 G alpha-galactosidase
KNIFDBKJ_01708 8.3e-202 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KNIFDBKJ_01709 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KNIFDBKJ_01710 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KNIFDBKJ_01711 5.9e-111 galR K Transcriptional regulator
KNIFDBKJ_01712 2.6e-288 lacS G Transporter
KNIFDBKJ_01713 0.0 lacL 3.2.1.23 G -beta-galactosidase
KNIFDBKJ_01714 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KNIFDBKJ_01715 3.8e-111 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KNIFDBKJ_01716 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KNIFDBKJ_01717 6.9e-92 yueF S AI-2E family transporter
KNIFDBKJ_01718 2.6e-97 ygaC J Belongs to the UPF0374 family
KNIFDBKJ_01719 4.7e-191 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KNIFDBKJ_01720 4.2e-67 recX 2.4.1.337 GT4 S Regulatory protein RecX
KNIFDBKJ_01721 1.8e-19 sigH K DNA-templated transcription, initiation
KNIFDBKJ_01722 7e-23 S Cytochrome B5
KNIFDBKJ_01723 7.3e-47 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
KNIFDBKJ_01724 4.4e-60
KNIFDBKJ_01725 1.4e-42 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KNIFDBKJ_01726 6.6e-156 nrnB S DHHA1 domain
KNIFDBKJ_01727 1.5e-91 yunF F Protein of unknown function DUF72
KNIFDBKJ_01728 2e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
KNIFDBKJ_01729 5.4e-13
KNIFDBKJ_01730 8.2e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KNIFDBKJ_01731 1e-29 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KNIFDBKJ_01732 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KNIFDBKJ_01733 5.3e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KNIFDBKJ_01734 4.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
KNIFDBKJ_01735 1.6e-180 pbuG S permease
KNIFDBKJ_01737 8e-79 S Cell surface protein
KNIFDBKJ_01739 2.9e-257 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
KNIFDBKJ_01740 2.8e-61
KNIFDBKJ_01741 3.6e-41 rpmE2 J Ribosomal protein L31
KNIFDBKJ_01742 3.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KNIFDBKJ_01743 4.6e-201 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNIFDBKJ_01746 6.2e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KNIFDBKJ_01747 9.9e-42 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KNIFDBKJ_01748 3.1e-32 ywiB S Domain of unknown function (DUF1934)
KNIFDBKJ_01749 3.4e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
KNIFDBKJ_01750 4.3e-205 ywfO S HD domain protein
KNIFDBKJ_01751 4e-89 S hydrolase
KNIFDBKJ_01752 2.7e-102 ydcZ S Putative inner membrane exporter, YdcZ
KNIFDBKJ_01753 3.7e-22
KNIFDBKJ_01754 1.7e-71
KNIFDBKJ_01756 4.1e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
KNIFDBKJ_01757 1e-22
KNIFDBKJ_01758 1.1e-55 spoVK O ATPase family associated with various cellular activities (AAA)
KNIFDBKJ_01760 2.6e-87 S overlaps another CDS with the same product name
KNIFDBKJ_01761 3.9e-124 S overlaps another CDS with the same product name
KNIFDBKJ_01762 1.7e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KNIFDBKJ_01763 5.7e-62 bCE_4747 S Beta-lactamase superfamily domain
KNIFDBKJ_01764 3.9e-290 ybiT S ABC transporter, ATP-binding protein
KNIFDBKJ_01765 2.5e-77 2.4.2.3 F Phosphorylase superfamily
KNIFDBKJ_01766 9e-26
KNIFDBKJ_01767 3.1e-113 dkg S reductase
KNIFDBKJ_01769 4.3e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNIFDBKJ_01770 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KNIFDBKJ_01771 1.5e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KNIFDBKJ_01772 4.3e-47 EGP Transmembrane secretion effector
KNIFDBKJ_01773 5.2e-137 purR 2.4.2.7 F pur operon repressor
KNIFDBKJ_01774 9.6e-52 adhR K helix_turn_helix, mercury resistance
KNIFDBKJ_01775 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KNIFDBKJ_01776 7.8e-40 2.4.1.9 GH68 M MucBP domain
KNIFDBKJ_01777 5.2e-87 L PFAM Integrase catalytic region
KNIFDBKJ_01779 7.8e-136 S interspecies interaction between organisms
KNIFDBKJ_01780 1.2e-207 G glycerol-3-phosphate transporter
KNIFDBKJ_01781 5.8e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KNIFDBKJ_01782 4.8e-145 htrA 3.4.21.107 O serine protease
KNIFDBKJ_01783 2.2e-116 vicX 3.1.26.11 S domain protein
KNIFDBKJ_01784 6.8e-30 yyaQ S YjbR
KNIFDBKJ_01785 5.6e-80 yycI S YycH protein
KNIFDBKJ_01786 7.9e-103 yycH S YycH protein
KNIFDBKJ_01787 1.5e-272 vicK 2.7.13.3 T Histidine kinase
KNIFDBKJ_01788 9e-114 K response regulator
KNIFDBKJ_01789 6.1e-106 yxeH S hydrolase
KNIFDBKJ_01790 1e-227 V ABC transporter transmembrane region
KNIFDBKJ_01791 1.1e-216 XK27_09600 V ABC transporter, ATP-binding protein
KNIFDBKJ_01792 7.1e-32 K Transcriptional regulator, MarR family
KNIFDBKJ_01793 8.9e-174 S Putative peptidoglycan binding domain
KNIFDBKJ_01794 3.8e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KNIFDBKJ_01795 1.1e-137 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
KNIFDBKJ_01796 1.5e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KNIFDBKJ_01797 3.1e-106 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KNIFDBKJ_01798 7e-205 pepF E Oligopeptidase F
KNIFDBKJ_01799 3.7e-96 yicL EG EamA-like transporter family
KNIFDBKJ_01800 1.6e-68 2.3.1.178 J Acetyltransferase (GNAT) domain
KNIFDBKJ_01801 1.6e-167 yjjP S Putative threonine/serine exporter
KNIFDBKJ_01802 1.7e-24 S PFAM Archaeal ATPase
KNIFDBKJ_01803 3e-60 S PFAM Archaeal ATPase
KNIFDBKJ_01804 2.7e-170 ydfJ EGP Sugar (and other) transporter
KNIFDBKJ_01805 1.3e-137 rspB 1.1.1.380 C Zinc-binding dehydrogenase
KNIFDBKJ_01806 4.4e-173 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
KNIFDBKJ_01807 2.5e-207 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
KNIFDBKJ_01808 1.5e-49 kdgR K FCD domain
KNIFDBKJ_01809 1e-113 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
KNIFDBKJ_01810 3.3e-62 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
KNIFDBKJ_01811 4.8e-109 glcU U sugar transport
KNIFDBKJ_01812 1e-14 yobS K transcriptional regulator
KNIFDBKJ_01813 2e-153 mdtG EGP Major facilitator Superfamily
KNIFDBKJ_01814 5e-98 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KNIFDBKJ_01815 4.2e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
KNIFDBKJ_01816 7.4e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KNIFDBKJ_01817 9.5e-18 yneR
KNIFDBKJ_01818 4.8e-247 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KNIFDBKJ_01819 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KNIFDBKJ_01820 2.1e-60 yiiE S Protein of unknown function (DUF1211)
KNIFDBKJ_01821 0.0 asnB 6.3.5.4 E Asparagine synthase
KNIFDBKJ_01822 7.4e-64 D peptidase
KNIFDBKJ_01823 7.3e-117 S Glycosyl transferase family 2
KNIFDBKJ_01824 4.8e-109 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
KNIFDBKJ_01825 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KNIFDBKJ_01826 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KNIFDBKJ_01827 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
KNIFDBKJ_01828 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNIFDBKJ_01829 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNIFDBKJ_01830 1.2e-152 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KNIFDBKJ_01831 9e-20 yaaA S S4 domain protein YaaA
KNIFDBKJ_01832 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KNIFDBKJ_01833 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KNIFDBKJ_01834 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KNIFDBKJ_01835 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KNIFDBKJ_01836 3.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KNIFDBKJ_01837 1.1e-199 nupG F Nucleoside
KNIFDBKJ_01838 1.3e-121 MA20_14895 S Conserved hypothetical protein 698
KNIFDBKJ_01839 1.7e-53 K LysR substrate binding domain
KNIFDBKJ_01840 9.6e-09
KNIFDBKJ_01841 3.2e-67 yxkH G Polysaccharide deacetylase
KNIFDBKJ_01842 9e-30 yqkB S Belongs to the HesB IscA family
KNIFDBKJ_01843 7.2e-38 L hmm pf00665
KNIFDBKJ_01844 1.8e-49 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
KNIFDBKJ_01845 8.7e-51 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
KNIFDBKJ_01846 3.4e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KNIFDBKJ_01847 3.9e-133 coaA 2.7.1.33 F Pantothenic acid kinase
KNIFDBKJ_01848 1.7e-44 E GDSL-like Lipase/Acylhydrolase
KNIFDBKJ_01849 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KNIFDBKJ_01850 1.6e-189 glnPH2 P ABC transporter permease
KNIFDBKJ_01851 2.1e-213 yjeM E Amino Acid
KNIFDBKJ_01852 3.9e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
KNIFDBKJ_01853 2.5e-137 tetA EGP Major facilitator Superfamily
KNIFDBKJ_01854 1.3e-62 S Glycosyltransferase like family 2
KNIFDBKJ_01855 1.5e-117 cps1D M Domain of unknown function (DUF4422)
KNIFDBKJ_01856 4.3e-38 S CAAX protease self-immunity
KNIFDBKJ_01857 9.1e-89 yvyE 3.4.13.9 S YigZ family
KNIFDBKJ_01858 2.3e-58 S Haloacid dehalogenase-like hydrolase
KNIFDBKJ_01859 4.5e-154 EGP Major facilitator Superfamily
KNIFDBKJ_01861 1.5e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KNIFDBKJ_01862 2.1e-27 yraB K transcriptional regulator
KNIFDBKJ_01863 2.9e-89 S NADPH-dependent FMN reductase
KNIFDBKJ_01864 3.4e-101 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KNIFDBKJ_01865 1.1e-55 S ECF transporter, substrate-specific component
KNIFDBKJ_01866 2.8e-103 znuB U ABC 3 transport family
KNIFDBKJ_01867 6.5e-98 fhuC P ABC transporter
KNIFDBKJ_01868 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
KNIFDBKJ_01869 1.5e-38
KNIFDBKJ_01870 7.3e-14 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
KNIFDBKJ_01871 4.2e-53 XK27_01040 S Protein of unknown function (DUF1129)
KNIFDBKJ_01872 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KNIFDBKJ_01873 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
KNIFDBKJ_01874 9.1e-108 spo0J K Belongs to the ParB family
KNIFDBKJ_01875 5.5e-117 soj D Sporulation initiation inhibitor
KNIFDBKJ_01876 9.5e-68 noc K Belongs to the ParB family
KNIFDBKJ_01877 8.1e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KNIFDBKJ_01878 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KNIFDBKJ_01879 2.4e-109 3.1.4.46 C phosphodiesterase
KNIFDBKJ_01880 0.0 pacL 3.6.3.8 P P-type ATPase
KNIFDBKJ_01881 3.6e-43 yvdD 3.2.2.10 S Possible lysine decarboxylase
KNIFDBKJ_01882 1.4e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KNIFDBKJ_01884 5.2e-63 srtA 3.4.22.70 M sortase family
KNIFDBKJ_01885 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KNIFDBKJ_01886 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KNIFDBKJ_01887 3.7e-34
KNIFDBKJ_01888 4.5e-140 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KNIFDBKJ_01889 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KNIFDBKJ_01890 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KNIFDBKJ_01891 1.1e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
KNIFDBKJ_01892 1.1e-39 ybjQ S Belongs to the UPF0145 family
KNIFDBKJ_01893 5.7e-08
KNIFDBKJ_01894 1.8e-95 V ABC transporter, ATP-binding protein
KNIFDBKJ_01895 6.9e-41 gntR1 K Transcriptional regulator, GntR family
KNIFDBKJ_01896 7.1e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
KNIFDBKJ_01897 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNIFDBKJ_01898 3.2e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
KNIFDBKJ_01899 2.2e-107 terC P Integral membrane protein TerC family
KNIFDBKJ_01900 5.5e-39 K Transcriptional regulator
KNIFDBKJ_01901 7.5e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KNIFDBKJ_01902 2e-100 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KNIFDBKJ_01903 4.5e-102 tcyB E ABC transporter
KNIFDBKJ_01904 2.3e-302 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KNIFDBKJ_01905 3.8e-140 mtlR K Mga helix-turn-helix domain
KNIFDBKJ_01906 6e-59 mtlR K Mga helix-turn-helix domain
KNIFDBKJ_01907 1.1e-175 yjcE P Sodium proton antiporter
KNIFDBKJ_01908 4.9e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KNIFDBKJ_01909 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
KNIFDBKJ_01910 3.3e-69 dhaL 2.7.1.121 S Dak2
KNIFDBKJ_01911 7.6e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
KNIFDBKJ_01912 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
KNIFDBKJ_01913 1.7e-61 K Bacterial regulatory proteins, tetR family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)