ORF_ID e_value Gene_name EC_number CAZy COGs Description
AICKPCKD_00001 5.2e-202 hsdM 2.1.1.72 V type I restriction-modification system
AICKPCKD_00002 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
AICKPCKD_00004 4.9e-22 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
AICKPCKD_00005 2.8e-56 3.6.1.27 I Acid phosphatase homologues
AICKPCKD_00006 2.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
AICKPCKD_00007 4.4e-74 2.3.1.178 M GNAT acetyltransferase
AICKPCKD_00009 1.2e-196 ade 3.5.4.2 F Adenine deaminase C-terminal domain
AICKPCKD_00010 1e-64 ypsA S Belongs to the UPF0398 family
AICKPCKD_00011 4.4e-189 nhaC C Na H antiporter NhaC
AICKPCKD_00012 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AICKPCKD_00013 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
AICKPCKD_00014 7.3e-113 xerD D recombinase XerD
AICKPCKD_00015 4.8e-125 cvfB S S1 domain
AICKPCKD_00016 1.3e-42 yeaL S Protein of unknown function (DUF441)
AICKPCKD_00017 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AICKPCKD_00018 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AICKPCKD_00019 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AICKPCKD_00020 4.5e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AICKPCKD_00021 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AICKPCKD_00022 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AICKPCKD_00023 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AICKPCKD_00024 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
AICKPCKD_00025 1.3e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
AICKPCKD_00026 1.2e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
AICKPCKD_00027 9.7e-73
AICKPCKD_00030 4.7e-09 M LysM domain
AICKPCKD_00031 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
AICKPCKD_00032 1e-27 ysxB J Cysteine protease Prp
AICKPCKD_00033 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
AICKPCKD_00036 2.2e-08 S Protein of unknown function (DUF2922)
AICKPCKD_00038 9.8e-17 K DNA-templated transcription, initiation
AICKPCKD_00040 1.2e-65 H Methyltransferase domain
AICKPCKD_00041 3.8e-75 cps2D 5.1.3.2 M RmlD substrate binding domain
AICKPCKD_00042 2.5e-41 wecD M Acetyltransferase (GNAT) family
AICKPCKD_00044 1.4e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
AICKPCKD_00045 4.4e-41 S Protein of unknown function (DUF1211)
AICKPCKD_00047 5e-86 1.1.1.1 C Zinc-binding dehydrogenase
AICKPCKD_00048 4.5e-30 S CHY zinc finger
AICKPCKD_00049 2.1e-39 K Transcriptional regulator
AICKPCKD_00050 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
AICKPCKD_00053 5.6e-126 M Glycosyl transferases group 1
AICKPCKD_00054 3.4e-64 M Glycosyl transferases group 1
AICKPCKD_00055 3.7e-179 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AICKPCKD_00056 5.5e-147 lspL 5.1.3.6 GM RmlD substrate binding domain
AICKPCKD_00057 2.2e-104 cps2I S Psort location CytoplasmicMembrane, score
AICKPCKD_00058 3.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
AICKPCKD_00059 2.3e-116 S Glycosyltransferase WbsX
AICKPCKD_00060 2.7e-52
AICKPCKD_00062 2.5e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
AICKPCKD_00063 1e-42 GT2 V Glycosyl transferase, family 2
AICKPCKD_00064 1.5e-75 M Glycosyltransferase Family 4
AICKPCKD_00065 1.8e-79 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
AICKPCKD_00066 5.3e-121 2.4.1.52 GT4 M Glycosyl transferases group 1
AICKPCKD_00067 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
AICKPCKD_00068 4.8e-77 epsL M Bacterial sugar transferase
AICKPCKD_00069 9.1e-167 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
AICKPCKD_00070 1.2e-221 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
AICKPCKD_00071 9.4e-65 cpsD D AAA domain
AICKPCKD_00072 1.4e-48 cps4C M Chain length determinant protein
AICKPCKD_00073 6.7e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
AICKPCKD_00074 2e-178 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
AICKPCKD_00075 4.8e-81
AICKPCKD_00076 1.6e-79 yjfP S COG1073 Hydrolases of the alpha beta superfamily
AICKPCKD_00077 2.3e-113 yitU 3.1.3.104 S hydrolase
AICKPCKD_00078 4.5e-60 speG J Acetyltransferase (GNAT) domain
AICKPCKD_00079 2e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AICKPCKD_00080 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
AICKPCKD_00081 1.3e-204 pipD E Dipeptidase
AICKPCKD_00082 2.3e-45
AICKPCKD_00083 3.5e-64 K helix_turn_helix, arabinose operon control protein
AICKPCKD_00084 8.9e-54 S Membrane
AICKPCKD_00085 0.0 rafA 3.2.1.22 G alpha-galactosidase
AICKPCKD_00086 7.6e-308 L Helicase C-terminal domain protein
AICKPCKD_00087 1.9e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
AICKPCKD_00088 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
AICKPCKD_00089 2.4e-113 2.7.7.65 T diguanylate cyclase activity
AICKPCKD_00090 0.0 ydaN S Bacterial cellulose synthase subunit
AICKPCKD_00091 1.2e-201 ydaM M Glycosyl transferase family group 2
AICKPCKD_00092 5.8e-206 S Protein conserved in bacteria
AICKPCKD_00093 6.5e-183
AICKPCKD_00094 1.7e-129 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
AICKPCKD_00095 2.4e-32 2.7.7.65 T GGDEF domain
AICKPCKD_00097 1.5e-146 pbuO_1 S Permease family
AICKPCKD_00098 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
AICKPCKD_00099 1.5e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
AICKPCKD_00100 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AICKPCKD_00101 3.6e-220 cydD CO ABC transporter transmembrane region
AICKPCKD_00102 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
AICKPCKD_00103 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
AICKPCKD_00104 1.3e-193 cydA 1.10.3.14 C ubiquinol oxidase
AICKPCKD_00105 2.6e-159 asnA 6.3.1.1 F aspartate--ammonia ligase
AICKPCKD_00106 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
AICKPCKD_00107 5e-19 glpE P Rhodanese Homology Domain
AICKPCKD_00108 5.5e-49 lytE M LysM domain protein
AICKPCKD_00109 1.4e-92 T Calcineurin-like phosphoesterase superfamily domain
AICKPCKD_00110 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
AICKPCKD_00112 4.4e-74 draG O ADP-ribosylglycohydrolase
AICKPCKD_00113 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AICKPCKD_00114 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AICKPCKD_00115 8.6e-62 divIVA D DivIVA domain protein
AICKPCKD_00116 1.7e-81 ylmH S S4 domain protein
AICKPCKD_00117 3e-19 yggT S YGGT family
AICKPCKD_00118 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
AICKPCKD_00119 9.8e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AICKPCKD_00120 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AICKPCKD_00121 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AICKPCKD_00122 1.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AICKPCKD_00123 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AICKPCKD_00124 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AICKPCKD_00125 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
AICKPCKD_00126 2.5e-11 ftsL D cell division protein FtsL
AICKPCKD_00127 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AICKPCKD_00128 1.5e-55 mraZ K Belongs to the MraZ family
AICKPCKD_00129 2.2e-07 S Protein of unknown function (DUF3397)
AICKPCKD_00130 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
AICKPCKD_00132 9.8e-100 D Alpha beta
AICKPCKD_00133 3.7e-109 aatB ET ABC transporter substrate-binding protein
AICKPCKD_00134 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AICKPCKD_00135 1.9e-94 glnP P ABC transporter permease
AICKPCKD_00136 1.8e-126 minD D Belongs to the ParA family
AICKPCKD_00137 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
AICKPCKD_00138 2e-54 mreD M rod shape-determining protein MreD
AICKPCKD_00139 2.1e-88 mreC M Involved in formation and maintenance of cell shape
AICKPCKD_00140 3.6e-156 mreB D cell shape determining protein MreB
AICKPCKD_00141 4.5e-21 K Cold shock
AICKPCKD_00142 8.1e-80 radC L DNA repair protein
AICKPCKD_00143 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AICKPCKD_00144 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AICKPCKD_00145 2.7e-195 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AICKPCKD_00146 6.4e-162 iscS2 2.8.1.7 E Aminotransferase class V
AICKPCKD_00147 5.8e-175 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AICKPCKD_00148 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
AICKPCKD_00149 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AICKPCKD_00150 3.4e-24 yueI S Protein of unknown function (DUF1694)
AICKPCKD_00151 5.1e-184 rarA L recombination factor protein RarA
AICKPCKD_00153 6e-72 usp6 T universal stress protein
AICKPCKD_00154 1.1e-53 tag 3.2.2.20 L glycosylase
AICKPCKD_00155 7.7e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AICKPCKD_00156 4.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
AICKPCKD_00158 3.3e-75 yviA S Protein of unknown function (DUF421)
AICKPCKD_00159 1.8e-27 S Protein of unknown function (DUF3290)
AICKPCKD_00160 1.7e-277 pbp2b 3.4.16.4 M Penicillin-binding Protein
AICKPCKD_00161 1.2e-296 S membrane
AICKPCKD_00162 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AICKPCKD_00163 4e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
AICKPCKD_00164 6.5e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
AICKPCKD_00165 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AICKPCKD_00167 1.4e-16
AICKPCKD_00168 6.2e-199 oatA I Acyltransferase
AICKPCKD_00169 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AICKPCKD_00170 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AICKPCKD_00171 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AICKPCKD_00174 5.1e-42 S Phosphoesterase
AICKPCKD_00175 2.2e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AICKPCKD_00176 1.1e-60 yslB S Protein of unknown function (DUF2507)
AICKPCKD_00177 9.9e-41 trxA O Belongs to the thioredoxin family
AICKPCKD_00178 3.9e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AICKPCKD_00179 9.5e-18 cvpA S Colicin V production protein
AICKPCKD_00180 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AICKPCKD_00181 1.9e-33 yrzB S Belongs to the UPF0473 family
AICKPCKD_00182 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AICKPCKD_00183 2.1e-36 yrzL S Belongs to the UPF0297 family
AICKPCKD_00184 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AICKPCKD_00185 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AICKPCKD_00186 2.7e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
AICKPCKD_00187 7.5e-13
AICKPCKD_00188 1e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AICKPCKD_00189 1.9e-66 yrjD S LUD domain
AICKPCKD_00190 8e-245 lutB C 4Fe-4S dicluster domain
AICKPCKD_00191 6.9e-117 lutA C Cysteine-rich domain
AICKPCKD_00192 2e-208 yfnA E Amino Acid
AICKPCKD_00194 9.6e-61 uspA T universal stress protein
AICKPCKD_00196 1.8e-12 yajC U Preprotein translocase
AICKPCKD_00197 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AICKPCKD_00198 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AICKPCKD_00199 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AICKPCKD_00200 1e-70 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AICKPCKD_00201 6e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AICKPCKD_00202 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AICKPCKD_00203 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
AICKPCKD_00204 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AICKPCKD_00205 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AICKPCKD_00206 2.9e-64 ymfM S Helix-turn-helix domain
AICKPCKD_00207 8.4e-91 IQ Enoyl-(Acyl carrier protein) reductase
AICKPCKD_00208 3e-147 ymfH S Peptidase M16
AICKPCKD_00209 3.5e-108 ymfF S Peptidase M16 inactive domain protein
AICKPCKD_00210 1.6e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
AICKPCKD_00211 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AICKPCKD_00212 4.1e-97 rrmA 2.1.1.187 H Methyltransferase
AICKPCKD_00213 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
AICKPCKD_00214 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AICKPCKD_00215 4e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AICKPCKD_00216 3.2e-21 cutC P Participates in the control of copper homeostasis
AICKPCKD_00217 4e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
AICKPCKD_00218 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
AICKPCKD_00219 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AICKPCKD_00220 5.3e-68 ybbR S YbbR-like protein
AICKPCKD_00221 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AICKPCKD_00222 2.4e-71 S Protein of unknown function (DUF1361)
AICKPCKD_00223 3.5e-115 murB 1.3.1.98 M Cell wall formation
AICKPCKD_00224 1.9e-68 dnaQ 2.7.7.7 L DNA polymerase III
AICKPCKD_00225 3.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
AICKPCKD_00226 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
AICKPCKD_00227 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AICKPCKD_00228 2.4e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
AICKPCKD_00229 9.1e-42 yxjI
AICKPCKD_00230 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AICKPCKD_00231 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AICKPCKD_00232 2.8e-19 secG U Preprotein translocase
AICKPCKD_00233 1.2e-179 clcA P chloride
AICKPCKD_00234 6.7e-146 lmrP E Major Facilitator Superfamily
AICKPCKD_00235 1.8e-169 T PhoQ Sensor
AICKPCKD_00236 5e-104 K response regulator
AICKPCKD_00237 2.2e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AICKPCKD_00238 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AICKPCKD_00239 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AICKPCKD_00240 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
AICKPCKD_00241 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AICKPCKD_00242 1.1e-136 cggR K Putative sugar-binding domain
AICKPCKD_00244 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AICKPCKD_00245 1.8e-149 whiA K May be required for sporulation
AICKPCKD_00246 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
AICKPCKD_00247 7.5e-126 rapZ S Displays ATPase and GTPase activities
AICKPCKD_00248 5e-79 ylbE GM NAD dependent epimerase dehydratase family protein
AICKPCKD_00249 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AICKPCKD_00250 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AICKPCKD_00251 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AICKPCKD_00252 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
AICKPCKD_00253 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AICKPCKD_00254 8.7e-133 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AICKPCKD_00255 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
AICKPCKD_00256 2.4e-08 pspC KT PspC domain
AICKPCKD_00257 1.2e-85 phoR 2.7.13.3 T Histidine kinase
AICKPCKD_00258 6e-86 K response regulator
AICKPCKD_00259 9.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
AICKPCKD_00260 2.2e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AICKPCKD_00261 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AICKPCKD_00262 9.1e-95 yeaN P Major Facilitator Superfamily
AICKPCKD_00263 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AICKPCKD_00264 5.6e-44 comFC S Competence protein
AICKPCKD_00265 3.2e-128 comFA L Helicase C-terminal domain protein
AICKPCKD_00266 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
AICKPCKD_00267 1.2e-295 ydaO E amino acid
AICKPCKD_00268 2.5e-269 aha1 P COG COG0474 Cation transport ATPase
AICKPCKD_00269 1.3e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AICKPCKD_00270 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AICKPCKD_00271 2.4e-33 S CAAX protease self-immunity
AICKPCKD_00272 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AICKPCKD_00273 6.9e-257 uup S ABC transporter, ATP-binding protein
AICKPCKD_00274 8.4e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AICKPCKD_00275 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
AICKPCKD_00276 3.7e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
AICKPCKD_00277 3.5e-140 ansA 3.5.1.1 EJ Asparaginase
AICKPCKD_00278 4.7e-81 fat 3.1.2.21 I Acyl-ACP thioesterase
AICKPCKD_00279 4.1e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AICKPCKD_00280 1.4e-40 yabA L Involved in initiation control of chromosome replication
AICKPCKD_00281 3.9e-83 holB 2.7.7.7 L DNA polymerase III
AICKPCKD_00282 1.4e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AICKPCKD_00283 9.2e-29 yaaL S Protein of unknown function (DUF2508)
AICKPCKD_00284 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AICKPCKD_00285 1.4e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AICKPCKD_00286 4.3e-210 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AICKPCKD_00287 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AICKPCKD_00288 1.1e-75 rsmC 2.1.1.172 J Methyltransferase
AICKPCKD_00289 1.2e-27 nrdH O Glutaredoxin
AICKPCKD_00290 4.8e-45 nrdI F NrdI Flavodoxin like
AICKPCKD_00291 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AICKPCKD_00292 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AICKPCKD_00293 1.6e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AICKPCKD_00294 1.4e-54
AICKPCKD_00295 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AICKPCKD_00296 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AICKPCKD_00297 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AICKPCKD_00298 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AICKPCKD_00299 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
AICKPCKD_00300 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
AICKPCKD_00301 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AICKPCKD_00302 5.4e-71 yacP S YacP-like NYN domain
AICKPCKD_00303 3.2e-109 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AICKPCKD_00304 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AICKPCKD_00305 1.8e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
AICKPCKD_00306 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AICKPCKD_00307 4.1e-153 yacL S domain protein
AICKPCKD_00308 5.4e-224 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AICKPCKD_00309 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
AICKPCKD_00310 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
AICKPCKD_00311 7.6e-223 pepC 3.4.22.40 E Peptidase C1-like family
AICKPCKD_00312 1e-33 S Enterocin A Immunity
AICKPCKD_00313 4.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AICKPCKD_00314 2.9e-128 mleP2 S Sodium Bile acid symporter family
AICKPCKD_00315 1.3e-115 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AICKPCKD_00317 7.2e-45 ydcK S Belongs to the SprT family
AICKPCKD_00318 8.2e-251 yhgF K Tex-like protein N-terminal domain protein
AICKPCKD_00319 3.6e-130 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AICKPCKD_00320 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AICKPCKD_00321 2.5e-90 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
AICKPCKD_00322 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
AICKPCKD_00323 5.9e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AICKPCKD_00325 1.1e-07
AICKPCKD_00326 7.9e-197 dtpT U amino acid peptide transporter
AICKPCKD_00329 8.6e-115 glcR K DeoR C terminal sensor domain
AICKPCKD_00330 4.5e-171 patA 2.6.1.1 E Aminotransferase
AICKPCKD_00331 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
AICKPCKD_00333 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AICKPCKD_00334 1.4e-172 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
AICKPCKD_00335 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
AICKPCKD_00336 6.2e-21 S Family of unknown function (DUF5322)
AICKPCKD_00337 5e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
AICKPCKD_00338 1.8e-38
AICKPCKD_00341 2.5e-149 EGP Sugar (and other) transporter
AICKPCKD_00342 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
AICKPCKD_00343 4.8e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AICKPCKD_00344 1.9e-183 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AICKPCKD_00345 4.2e-73 alkD L DNA alkylation repair enzyme
AICKPCKD_00346 6.4e-136 EG EamA-like transporter family
AICKPCKD_00347 3.6e-150 S Tetratricopeptide repeat protein
AICKPCKD_00348 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
AICKPCKD_00349 4.3e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AICKPCKD_00350 7e-127 corA P CorA-like Mg2+ transporter protein
AICKPCKD_00351 8.5e-161 nhaC C Na H antiporter NhaC
AICKPCKD_00352 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AICKPCKD_00353 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
AICKPCKD_00355 7.2e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AICKPCKD_00356 2.9e-154 iscS 2.8.1.7 E Aminotransferase class V
AICKPCKD_00357 3.7e-41 XK27_04120 S Putative amino acid metabolism
AICKPCKD_00358 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AICKPCKD_00359 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AICKPCKD_00360 4.3e-15 S Protein of unknown function (DUF2929)
AICKPCKD_00361 0.0 dnaE 2.7.7.7 L DNA polymerase
AICKPCKD_00362 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AICKPCKD_00363 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
AICKPCKD_00365 1e-39 ypaA S Protein of unknown function (DUF1304)
AICKPCKD_00366 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AICKPCKD_00367 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AICKPCKD_00368 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AICKPCKD_00369 1.2e-196 FbpA K Fibronectin-binding protein
AICKPCKD_00370 2.3e-40 K Transcriptional regulator
AICKPCKD_00371 2.2e-117 degV S EDD domain protein, DegV family
AICKPCKD_00372 7.8e-71 lepB 3.4.21.89 U Signal peptidase, peptidase S26
AICKPCKD_00373 2.4e-40 6.3.3.2 S ASCH
AICKPCKD_00374 1.2e-185 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AICKPCKD_00375 1.7e-79 yjjH S Calcineurin-like phosphoesterase
AICKPCKD_00376 3.1e-95 EG EamA-like transporter family
AICKPCKD_00377 2.3e-85 natB CP ABC-type Na efflux pump, permease component
AICKPCKD_00378 6.2e-112 natA S Domain of unknown function (DUF4162)
AICKPCKD_00379 4.8e-23 K Acetyltransferase (GNAT) domain
AICKPCKD_00381 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AICKPCKD_00382 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
AICKPCKD_00383 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
AICKPCKD_00384 9.1e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
AICKPCKD_00385 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AICKPCKD_00386 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AICKPCKD_00387 1.4e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
AICKPCKD_00388 4.5e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AICKPCKD_00389 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
AICKPCKD_00390 4.5e-90 recO L Involved in DNA repair and RecF pathway recombination
AICKPCKD_00391 1e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AICKPCKD_00392 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
AICKPCKD_00393 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AICKPCKD_00394 3.5e-153 phoH T phosphate starvation-inducible protein PhoH
AICKPCKD_00395 7.5e-83 lytH 3.5.1.28 M Ami_3
AICKPCKD_00396 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
AICKPCKD_00397 5.9e-12 M Lysin motif
AICKPCKD_00398 2e-128 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
AICKPCKD_00399 7.1e-59 ypbB 5.1.3.1 S Helix-turn-helix domain
AICKPCKD_00400 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
AICKPCKD_00401 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
AICKPCKD_00402 7.1e-120 ica2 GT2 M Glycosyl transferase family group 2
AICKPCKD_00403 4.8e-44
AICKPCKD_00404 2.8e-91 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AICKPCKD_00406 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AICKPCKD_00407 1.3e-212 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AICKPCKD_00408 4e-279 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
AICKPCKD_00409 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
AICKPCKD_00410 3.3e-117 EGP Major Facilitator Superfamily
AICKPCKD_00411 1.1e-124 akr5f 1.1.1.346 S reductase
AICKPCKD_00412 2.7e-72 K Transcriptional regulator
AICKPCKD_00413 9.9e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
AICKPCKD_00414 9.7e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AICKPCKD_00415 7.8e-38 K transcriptional regulator PadR family
AICKPCKD_00416 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
AICKPCKD_00417 1.2e-15 S Putative adhesin
AICKPCKD_00418 2.2e-16 pspC KT PspC domain
AICKPCKD_00420 5.1e-13 S Enterocin A Immunity
AICKPCKD_00421 4e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AICKPCKD_00422 1.3e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
AICKPCKD_00423 4.3e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AICKPCKD_00424 1.1e-166 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AICKPCKD_00425 1.5e-120 potB P ABC transporter permease
AICKPCKD_00426 4.5e-104 potC U Binding-protein-dependent transport system inner membrane component
AICKPCKD_00427 1.3e-159 potD P ABC transporter
AICKPCKD_00428 3.5e-132 ABC-SBP S ABC transporter
AICKPCKD_00429 3.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
AICKPCKD_00430 6.7e-107 XK27_08845 S ABC transporter, ATP-binding protein
AICKPCKD_00431 2.8e-66 M ErfK YbiS YcfS YnhG
AICKPCKD_00432 1.2e-53 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AICKPCKD_00433 4.2e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AICKPCKD_00434 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AICKPCKD_00435 1.2e-102 pgm3 G phosphoglycerate mutase
AICKPCKD_00436 4.7e-56 S CAAX protease self-immunity
AICKPCKD_00437 2.2e-47 C Flavodoxin
AICKPCKD_00438 9.7e-60 yphH S Cupin domain
AICKPCKD_00439 3.6e-46 yphJ 4.1.1.44 S decarboxylase
AICKPCKD_00440 2.9e-143 E methionine synthase, vitamin-B12 independent
AICKPCKD_00441 3.7e-106 metQ1 P Belongs to the nlpA lipoprotein family
AICKPCKD_00442 1.5e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AICKPCKD_00443 2.7e-70 metI P ABC transporter permease
AICKPCKD_00444 3.3e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
AICKPCKD_00445 3e-84 drgA C nitroreductase
AICKPCKD_00446 2.5e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
AICKPCKD_00447 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
AICKPCKD_00448 8.1e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
AICKPCKD_00449 1.4e-263 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
AICKPCKD_00451 2.3e-150 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AICKPCKD_00452 2.4e-31 metI U ABC transporter permease
AICKPCKD_00453 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
AICKPCKD_00454 1.8e-53 S Protein of unknown function (DUF4256)
AICKPCKD_00457 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
AICKPCKD_00458 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
AICKPCKD_00459 2.6e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AICKPCKD_00460 4e-230 lpdA 1.8.1.4 C Dehydrogenase
AICKPCKD_00461 2.1e-148 lplA 6.3.1.20 H Lipoate-protein ligase
AICKPCKD_00462 9.2e-56 S Protein of unknown function (DUF975)
AICKPCKD_00463 5.7e-78 E GDSL-like Lipase/Acylhydrolase family
AICKPCKD_00464 1.4e-38
AICKPCKD_00465 4.1e-27 gcvR T Belongs to the UPF0237 family
AICKPCKD_00466 6.1e-220 XK27_08635 S UPF0210 protein
AICKPCKD_00467 4.5e-87 fruR K DeoR C terminal sensor domain
AICKPCKD_00468 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
AICKPCKD_00469 4.8e-282 fruA 2.7.1.202 GT Phosphotransferase System
AICKPCKD_00470 5.5e-144 dapE 3.5.1.18 E Peptidase dimerisation domain
AICKPCKD_00471 1e-149 E glutamate:sodium symporter activity
AICKPCKD_00472 1.2e-145 Q Imidazolonepropionase and related amidohydrolases
AICKPCKD_00473 9.1e-50 cps3F
AICKPCKD_00474 3e-82 S Membrane
AICKPCKD_00475 1.8e-254 E Amino acid permease
AICKPCKD_00476 2.9e-225 cadA P P-type ATPase
AICKPCKD_00477 6.4e-114 degV S EDD domain protein, DegV family
AICKPCKD_00478 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
AICKPCKD_00479 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
AICKPCKD_00480 7.2e-27 ydiI Q Thioesterase superfamily
AICKPCKD_00481 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AICKPCKD_00482 3.5e-141 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
AICKPCKD_00483 5.6e-82 S L,D-transpeptidase catalytic domain
AICKPCKD_00484 8.8e-166 EGP Major facilitator Superfamily
AICKPCKD_00485 2.3e-21 K helix_turn_helix multiple antibiotic resistance protein
AICKPCKD_00486 1.7e-225 pipD E Dipeptidase
AICKPCKD_00487 4.1e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AICKPCKD_00488 2.6e-32 ywjH S Protein of unknown function (DUF1634)
AICKPCKD_00489 6.5e-119 yxaA S membrane transporter protein
AICKPCKD_00490 1.7e-82 lysR5 K LysR substrate binding domain
AICKPCKD_00491 7.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
AICKPCKD_00492 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AICKPCKD_00493 7.3e-271 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
AICKPCKD_00494 2.3e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
AICKPCKD_00495 1.9e-243 lysP E amino acid
AICKPCKD_00496 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AICKPCKD_00497 2.6e-29 yqkB S Belongs to the HesB IscA family
AICKPCKD_00498 2.3e-65 yxkH G Polysaccharide deacetylase
AICKPCKD_00499 9.6e-09
AICKPCKD_00500 2.9e-53 K LysR substrate binding domain
AICKPCKD_00501 2e-122 MA20_14895 S Conserved hypothetical protein 698
AICKPCKD_00502 1.1e-199 nupG F Nucleoside
AICKPCKD_00503 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AICKPCKD_00504 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AICKPCKD_00505 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
AICKPCKD_00506 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AICKPCKD_00507 3.9e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AICKPCKD_00508 9e-20 yaaA S S4 domain protein YaaA
AICKPCKD_00509 9.3e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AICKPCKD_00510 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AICKPCKD_00511 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AICKPCKD_00512 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
AICKPCKD_00513 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AICKPCKD_00514 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AICKPCKD_00515 2.5e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
AICKPCKD_00516 9.5e-117 S Glycosyl transferase family 2
AICKPCKD_00517 7.4e-64 D peptidase
AICKPCKD_00518 0.0 asnB 6.3.5.4 E Asparagine synthase
AICKPCKD_00519 3.7e-37 yiiE S Protein of unknown function (DUF1211)
AICKPCKD_00520 3.3e-12 yiiE S Protein of unknown function (DUF1211)
AICKPCKD_00521 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AICKPCKD_00522 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AICKPCKD_00523 3.6e-17 yneR
AICKPCKD_00524 1.5e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AICKPCKD_00525 2.2e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
AICKPCKD_00526 3.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
AICKPCKD_00527 3.8e-152 mdtG EGP Major facilitator Superfamily
AICKPCKD_00528 3.8e-14 yobS K transcriptional regulator
AICKPCKD_00529 2.8e-109 glcU U sugar transport
AICKPCKD_00530 4.4e-170 yjjP S Putative threonine/serine exporter
AICKPCKD_00531 2.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
AICKPCKD_00532 2.2e-96 yicL EG EamA-like transporter family
AICKPCKD_00533 4.6e-223 pepF E Oligopeptidase F
AICKPCKD_00534 1.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AICKPCKD_00535 4.4e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
AICKPCKD_00536 1.1e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
AICKPCKD_00537 8.4e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
AICKPCKD_00538 4e-23 relB L RelB antitoxin
AICKPCKD_00540 9.8e-173 S Putative peptidoglycan binding domain
AICKPCKD_00541 1.2e-31 K Transcriptional regulator, MarR family
AICKPCKD_00542 3.1e-216 XK27_09600 V ABC transporter, ATP-binding protein
AICKPCKD_00543 1.1e-229 V ABC transporter transmembrane region
AICKPCKD_00545 3.3e-96 S Domain of unknown function DUF87
AICKPCKD_00547 6.3e-85 yxeH S hydrolase
AICKPCKD_00548 9e-114 K response regulator
AICKPCKD_00549 1.1e-272 vicK 2.7.13.3 T Histidine kinase
AICKPCKD_00550 4.6e-103 yycH S YycH protein
AICKPCKD_00551 5.6e-80 yycI S YycH protein
AICKPCKD_00552 1.8e-30 yyaQ S YjbR
AICKPCKD_00553 1.3e-116 vicX 3.1.26.11 S domain protein
AICKPCKD_00554 3.7e-145 htrA 3.4.21.107 O serine protease
AICKPCKD_00555 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AICKPCKD_00556 4.4e-40 1.6.5.2 GM NAD(P)H-binding
AICKPCKD_00557 3.3e-25 K MarR family transcriptional regulator
AICKPCKD_00558 5.9e-88 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
AICKPCKD_00559 1.7e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
AICKPCKD_00560 4.2e-208 G glycerol-3-phosphate transporter
AICKPCKD_00561 5.9e-30 L Helix-turn-helix domain
AICKPCKD_00562 3.6e-69 L HTH-like domain
AICKPCKD_00563 2.1e-71 L PFAM transposase IS200-family protein
AICKPCKD_00564 2e-46 S CRISPR-associated protein (Cas_Csn2)
AICKPCKD_00565 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AICKPCKD_00566 3e-106 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AICKPCKD_00567 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
AICKPCKD_00568 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
AICKPCKD_00569 2.4e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
AICKPCKD_00570 1.6e-163 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AICKPCKD_00571 4.7e-130 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AICKPCKD_00572 2.1e-70 mltD CBM50 M NlpC P60 family protein
AICKPCKD_00573 3.2e-52 manO S Domain of unknown function (DUF956)
AICKPCKD_00574 2.1e-147 manN G system, mannose fructose sorbose family IID component
AICKPCKD_00575 6.4e-116 manY G PTS system sorbose-specific iic component
AICKPCKD_00576 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
AICKPCKD_00577 7e-80 rbsB G sugar-binding domain protein
AICKPCKD_00578 1.6e-100 baeS T Histidine kinase
AICKPCKD_00579 3e-79 baeR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AICKPCKD_00580 6.9e-120 G Bacterial extracellular solute-binding protein
AICKPCKD_00581 9.1e-71 S Protein of unknown function (DUF554)
AICKPCKD_00582 1.8e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AICKPCKD_00583 4.2e-32 merR K MerR HTH family regulatory protein
AICKPCKD_00584 1.8e-196 lmrB EGP Major facilitator Superfamily
AICKPCKD_00585 1.2e-33 S Domain of unknown function (DUF4811)
AICKPCKD_00586 1.9e-41 S CAAX protease self-immunity
AICKPCKD_00587 1e-60 yceE S haloacid dehalogenase-like hydrolase
AICKPCKD_00588 7.6e-74 glcR K DeoR C terminal sensor domain
AICKPCKD_00589 2.5e-95 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AICKPCKD_00590 5.7e-184 lmrB EGP Major facilitator Superfamily
AICKPCKD_00591 1.2e-54 bioY S BioY family
AICKPCKD_00592 2e-93 S Predicted membrane protein (DUF2207)
AICKPCKD_00593 1.4e-19
AICKPCKD_00594 1.4e-102 pfoS S Phosphotransferase system, EIIC
AICKPCKD_00595 5.3e-120 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AICKPCKD_00596 1.1e-43 K helix_turn_helix isocitrate lyase regulation
AICKPCKD_00597 4.3e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
AICKPCKD_00598 2.2e-58 ktrA P TrkA-N domain
AICKPCKD_00599 2.1e-114 ntpJ P Potassium uptake protein
AICKPCKD_00600 2e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
AICKPCKD_00601 6.1e-282 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
AICKPCKD_00602 1.8e-217 scrB 3.2.1.26 GH32 G invertase
AICKPCKD_00603 1.7e-147 scrR K helix_turn _helix lactose operon repressor
AICKPCKD_00604 5.8e-44 L hmm pf00665
AICKPCKD_00605 1.1e-98 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
AICKPCKD_00606 1.2e-84 dps P Ferritin-like domain
AICKPCKD_00607 2e-159 L transposase, IS605 OrfB family
AICKPCKD_00608 1.2e-57 tlpA2 L Transposase IS200 like
AICKPCKD_00609 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
AICKPCKD_00611 9e-102 qmcA O prohibitin homologues
AICKPCKD_00612 4.7e-26 S protein encoded in hypervariable junctions of pilus gene clusters
AICKPCKD_00613 0.0 O Belongs to the peptidase S8 family
AICKPCKD_00614 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AICKPCKD_00615 7.3e-118 O AAA domain (Cdc48 subfamily)
AICKPCKD_00616 4.1e-67
AICKPCKD_00617 8.6e-90 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
AICKPCKD_00618 4e-225 hsdM 2.1.1.72 V type I restriction-modification system
AICKPCKD_00619 2.4e-286 hsdR 3.1.21.3 L DEAD/DEAH box helicase
AICKPCKD_00620 4.4e-07
AICKPCKD_00621 1.1e-45 yjaB_1 K Acetyltransferase (GNAT) domain
AICKPCKD_00622 7.7e-80 yitS S EDD domain protein, DegV family
AICKPCKD_00623 1.9e-57 racA K Domain of unknown function (DUF1836)
AICKPCKD_00624 2.7e-116 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AICKPCKD_00625 2.7e-48 ald 1.4.1.1 C Belongs to the AlaDH PNT family
AICKPCKD_00626 5.4e-87 ald 1.4.1.1 C Belongs to the AlaDH PNT family
AICKPCKD_00627 1.3e-161 potE2 E amino acid
AICKPCKD_00630 4.6e-24
AICKPCKD_00631 6.9e-15
AICKPCKD_00632 7.4e-92 pstS P T5orf172
AICKPCKD_00633 2.4e-257 yeeB L DEAD-like helicases superfamily
AICKPCKD_00634 6.9e-206 yeeA V Type II restriction enzyme, methylase subunits
AICKPCKD_00635 8.8e-50 yugI 5.3.1.9 J general stress protein
AICKPCKD_00636 2.7e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
AICKPCKD_00637 3e-92 dedA S SNARE associated Golgi protein
AICKPCKD_00638 7.8e-32 S Protein of unknown function (DUF1461)
AICKPCKD_00639 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AICKPCKD_00640 1.9e-53 yutD S Protein of unknown function (DUF1027)
AICKPCKD_00641 3e-57 S Calcineurin-like phosphoesterase
AICKPCKD_00642 9.3e-184 cycA E Amino acid permease
AICKPCKD_00643 7.6e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
AICKPCKD_00645 5.5e-11 S Putative Competence protein ComGF
AICKPCKD_00647 1.5e-13
AICKPCKD_00648 1.2e-27 comGC U competence protein ComGC
AICKPCKD_00649 5.7e-98 comGB NU type II secretion system
AICKPCKD_00650 4.7e-121 comGA NU Type II IV secretion system protein
AICKPCKD_00651 2.1e-102 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AICKPCKD_00652 1.5e-119 yebC K Transcriptional regulatory protein
AICKPCKD_00653 1.5e-29 S VanZ like family
AICKPCKD_00654 1.3e-158 ccpA K catabolite control protein A
AICKPCKD_00655 1e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
AICKPCKD_00656 1.5e-13
AICKPCKD_00659 5.9e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AICKPCKD_00660 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
AICKPCKD_00661 5.2e-65 hly S protein, hemolysin III
AICKPCKD_00662 7.3e-41 M1-874 K Domain of unknown function (DUF1836)
AICKPCKD_00663 9.4e-84 S membrane
AICKPCKD_00664 1.1e-79 S VIT family
AICKPCKD_00665 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
AICKPCKD_00666 7.9e-56 P Plays a role in the regulation of phosphate uptake
AICKPCKD_00667 1.8e-115 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AICKPCKD_00668 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AICKPCKD_00669 3e-122 pstA P Phosphate transport system permease protein PstA
AICKPCKD_00670 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
AICKPCKD_00671 3.2e-97 pstS P Phosphate
AICKPCKD_00672 1.3e-41 yjbH Q Thioredoxin
AICKPCKD_00673 3.3e-232 pepF E oligoendopeptidase F
AICKPCKD_00674 1.1e-68 coiA 3.6.4.12 S Competence protein
AICKPCKD_00675 2.1e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AICKPCKD_00676 1.4e-218 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
AICKPCKD_00680 2.3e-56 S Putative HNHc nuclease
AICKPCKD_00681 8.6e-30 S Phage replisome organizer, N-terminal domain protein
AICKPCKD_00684 1.6e-25
AICKPCKD_00685 3.7e-70
AICKPCKD_00691 7.8e-21
AICKPCKD_00693 5.3e-62 Q DNA (cytosine-5-)-methyltransferase activity
AICKPCKD_00698 1.7e-33 arpU S Phage transcriptional regulator, ArpU family
AICKPCKD_00699 1.2e-40 gepA S Protein of unknown function (DUF4065)
AICKPCKD_00701 1.9e-37
AICKPCKD_00705 2.2e-72 L HNH nucleases
AICKPCKD_00706 4.3e-83 L Phage terminase, small subunit
AICKPCKD_00707 0.0 S Phage Terminase
AICKPCKD_00709 3.2e-193 S Phage portal protein
AICKPCKD_00710 9.1e-114 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
AICKPCKD_00711 1.1e-196 S Phage capsid family
AICKPCKD_00712 8.2e-22 S Phage gp6-like head-tail connector protein
AICKPCKD_00713 9.3e-59 S Phage head-tail joining protein
AICKPCKD_00714 2e-62 S Bacteriophage HK97-gp10, putative tail-component
AICKPCKD_00715 1.2e-56 S Protein of unknown function (DUF806)
AICKPCKD_00716 1.6e-78 S Phage tail tube protein
AICKPCKD_00717 9.8e-17 S Phage tail assembly chaperone proteins, TAC
AICKPCKD_00719 8.4e-296 M Phage tail tape measure protein TP901
AICKPCKD_00720 7.9e-77 S Phage tail protein
AICKPCKD_00721 1.3e-121 rny D peptidase
AICKPCKD_00723 3.4e-72 S Domain of unknown function (DUF2479)
AICKPCKD_00728 2.8e-09 hol S Bacteriophage holin
AICKPCKD_00729 1.2e-129 M Glycosyl hydrolases family 25
AICKPCKD_00730 8.5e-89 2.7.7.65 T phosphorelay sensor kinase activity
AICKPCKD_00731 1.3e-132 cbiQ P Cobalt transport protein
AICKPCKD_00732 4.6e-157 P ABC transporter
AICKPCKD_00733 1.2e-149 cbiO2 P ABC transporter
AICKPCKD_00734 1.2e-262 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
AICKPCKD_00735 4.9e-179 proV E ABC transporter, ATP-binding protein
AICKPCKD_00736 4.4e-247 gshR 1.8.1.7 C Glutathione reductase
AICKPCKD_00737 2.5e-101 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
AICKPCKD_00738 1.1e-107
AICKPCKD_00739 3.5e-40 S RelB antitoxin
AICKPCKD_00740 4e-44
AICKPCKD_00742 4.1e-98 norB EGP Major Facilitator
AICKPCKD_00743 1.5e-103 tag 3.2.2.20 L Methyladenine glycosylase
AICKPCKD_00744 1.8e-235 stp_1 EGP Major facilitator Superfamily
AICKPCKD_00745 2.4e-71 H ThiF family
AICKPCKD_00746 6.3e-207 arsR K DNA-binding transcription factor activity
AICKPCKD_00747 6.2e-97 K Transcriptional regulator
AICKPCKD_00748 2.7e-23 L Transposase
AICKPCKD_00749 2.8e-79 L Transposase and inactivated derivatives IS30 family
AICKPCKD_00750 1e-45 S Signal peptide protein, YSIRK family
AICKPCKD_00751 5.1e-77 K response regulator
AICKPCKD_00752 1.3e-89 saeS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
AICKPCKD_00753 1.5e-23 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AICKPCKD_00754 3.1e-110 L hmm pf00665
AICKPCKD_00755 2.5e-104 L Helix-turn-helix domain
AICKPCKD_00756 1.2e-100 pncA Q Isochorismatase family
AICKPCKD_00757 1.5e-269 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AICKPCKD_00758 1.1e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
AICKPCKD_00759 8.3e-164 C Luciferase-like monooxygenase
AICKPCKD_00760 3.6e-41 K Transcriptional regulator, HxlR family
AICKPCKD_00761 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AICKPCKD_00762 1.2e-103 ydhQ K UbiC transcription regulator-associated domain protein
AICKPCKD_00763 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
AICKPCKD_00764 2.4e-82 pncA Q isochorismatase
AICKPCKD_00765 3.5e-63 3.1.3.73 G phosphoglycerate mutase
AICKPCKD_00766 3.3e-259 treB G phosphotransferase system
AICKPCKD_00767 5.7e-84 treR K UTRA
AICKPCKD_00768 6.3e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
AICKPCKD_00769 6.4e-168 mdtG EGP Major facilitator Superfamily
AICKPCKD_00771 1.5e-194 XK27_08315 M Sulfatase
AICKPCKD_00772 5e-57 S peptidoglycan catabolic process
AICKPCKD_00773 5.6e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AICKPCKD_00774 5.2e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
AICKPCKD_00775 2.4e-128 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AICKPCKD_00776 4.1e-177 thrC 4.2.3.1 E Threonine synthase
AICKPCKD_00777 3.5e-82 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AICKPCKD_00778 6.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
AICKPCKD_00779 9.8e-135 K Transcriptional regulator
AICKPCKD_00780 2.3e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AICKPCKD_00781 1.5e-84 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AICKPCKD_00782 5.9e-192 carB 6.3.5.5 F Carbamoyl-phosphate synthase
AICKPCKD_00783 4.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AICKPCKD_00784 2.7e-204 pyrP F Permease
AICKPCKD_00785 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AICKPCKD_00786 7.3e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AICKPCKD_00787 1.3e-41 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AICKPCKD_00788 6.7e-57 3.1.3.18 J HAD-hyrolase-like
AICKPCKD_00789 1.7e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AICKPCKD_00790 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AICKPCKD_00791 3.1e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AICKPCKD_00792 5.8e-118 prmA J Ribosomal protein L11 methyltransferase
AICKPCKD_00793 7.6e-43 XK27_03960 S Protein of unknown function (DUF3013)
AICKPCKD_00794 1.5e-143 iunH2 3.2.2.1 F nucleoside hydrolase
AICKPCKD_00795 6.4e-12
AICKPCKD_00808 2.1e-07
AICKPCKD_00816 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
AICKPCKD_00817 1.4e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AICKPCKD_00818 3.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AICKPCKD_00819 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
AICKPCKD_00820 2.5e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AICKPCKD_00822 1.6e-55 ctsR K Belongs to the CtsR family
AICKPCKD_00823 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AICKPCKD_00824 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AICKPCKD_00825 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AICKPCKD_00826 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
AICKPCKD_00827 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AICKPCKD_00828 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AICKPCKD_00829 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AICKPCKD_00830 1.3e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
AICKPCKD_00831 1.2e-89 patB 4.4.1.8 E Aminotransferase, class I
AICKPCKD_00832 2.5e-113 K response regulator
AICKPCKD_00833 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
AICKPCKD_00834 2.2e-90 lacX 5.1.3.3 G Aldose 1-epimerase
AICKPCKD_00835 1.9e-20 G Transporter, major facilitator family protein
AICKPCKD_00836 3.7e-115 G Transporter, major facilitator family protein
AICKPCKD_00837 7e-224 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AICKPCKD_00838 7.3e-246 yhcA V ABC transporter, ATP-binding protein
AICKPCKD_00839 5.8e-35 K Bacterial regulatory proteins, tetR family
AICKPCKD_00840 4.6e-37 lmrA V ABC transporter, ATP-binding protein
AICKPCKD_00841 3.6e-172 lmrA V ABC transporter, ATP-binding protein
AICKPCKD_00842 3.3e-253 yfiC V ABC transporter
AICKPCKD_00844 3.2e-45 yjcF K protein acetylation
AICKPCKD_00845 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
AICKPCKD_00846 1.5e-71 lemA S LemA family
AICKPCKD_00847 1.3e-114 htpX O Belongs to the peptidase M48B family
AICKPCKD_00849 2.3e-272 helD 3.6.4.12 L DNA helicase
AICKPCKD_00850 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AICKPCKD_00851 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
AICKPCKD_00852 9.4e-103 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
AICKPCKD_00853 8.4e-83 ybhF_2 V abc transporter atp-binding protein
AICKPCKD_00854 3.5e-104 ybhR V ABC transporter
AICKPCKD_00855 2.3e-31 K Transcriptional regulator
AICKPCKD_00856 7.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
AICKPCKD_00857 2.1e-153 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
AICKPCKD_00858 4.3e-127
AICKPCKD_00859 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AICKPCKD_00860 8.3e-105 tatD L hydrolase, TatD family
AICKPCKD_00861 1.7e-86 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AICKPCKD_00862 7.5e-134 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AICKPCKD_00863 1.2e-22 veg S Biofilm formation stimulator VEG
AICKPCKD_00864 1.7e-90 S Alpha/beta hydrolase of unknown function (DUF915)
AICKPCKD_00865 4.2e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
AICKPCKD_00866 6.6e-46 argR K Regulates arginine biosynthesis genes
AICKPCKD_00867 2.8e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AICKPCKD_00868 2.3e-155 amtB P ammonium transporter
AICKPCKD_00870 7.7e-90 yqeH S Ribosome biogenesis GTPase YqeH
AICKPCKD_00871 1e-29 yhbY J RNA-binding protein
AICKPCKD_00872 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AICKPCKD_00873 7.2e-72 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
AICKPCKD_00874 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AICKPCKD_00875 4.2e-82 H Nodulation protein S (NodS)
AICKPCKD_00876 1.3e-122 ylbM S Belongs to the UPF0348 family
AICKPCKD_00877 2e-57 yceD S Uncharacterized ACR, COG1399
AICKPCKD_00878 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
AICKPCKD_00879 1.2e-88 plsC 2.3.1.51 I Acyltransferase
AICKPCKD_00880 1.1e-93 yabB 2.1.1.223 L Methyltransferase small domain
AICKPCKD_00881 1.5e-27 yazA L GIY-YIG catalytic domain protein
AICKPCKD_00882 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
AICKPCKD_00883 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AICKPCKD_00884 6.9e-37
AICKPCKD_00885 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
AICKPCKD_00886 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AICKPCKD_00887 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AICKPCKD_00888 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AICKPCKD_00889 8.6e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
AICKPCKD_00891 3.1e-111 K response regulator
AICKPCKD_00892 5e-167 arlS 2.7.13.3 T Histidine kinase
AICKPCKD_00893 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AICKPCKD_00894 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
AICKPCKD_00895 5.6e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
AICKPCKD_00896 7.3e-105
AICKPCKD_00897 7.2e-117
AICKPCKD_00898 1.3e-41 dut S dUTPase
AICKPCKD_00899 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AICKPCKD_00900 3.7e-46 yqhY S Asp23 family, cell envelope-related function
AICKPCKD_00901 1.9e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AICKPCKD_00902 1.7e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AICKPCKD_00903 1.2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AICKPCKD_00904 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AICKPCKD_00905 4.7e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AICKPCKD_00906 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
AICKPCKD_00907 6.6e-49 argR K Regulates arginine biosynthesis genes
AICKPCKD_00908 4.2e-178 recN L May be involved in recombinational repair of damaged DNA
AICKPCKD_00909 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AICKPCKD_00910 2.2e-30 ynzC S UPF0291 protein
AICKPCKD_00911 5.9e-27 yneF S UPF0154 protein
AICKPCKD_00912 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
AICKPCKD_00913 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
AICKPCKD_00914 1.2e-74 yciQ P membrane protein (DUF2207)
AICKPCKD_00915 3e-19 D nuclear chromosome segregation
AICKPCKD_00916 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AICKPCKD_00917 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AICKPCKD_00918 7.4e-70 gluP 3.4.21.105 S Peptidase, S54 family
AICKPCKD_00919 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
AICKPCKD_00920 4.7e-158 glk 2.7.1.2 G Glucokinase
AICKPCKD_00921 2.7e-46 yqhL P Rhodanese-like protein
AICKPCKD_00922 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
AICKPCKD_00923 1.9e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AICKPCKD_00924 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
AICKPCKD_00925 1.3e-45 glnR K Transcriptional regulator
AICKPCKD_00926 2e-247 glnA 6.3.1.2 E glutamine synthetase
AICKPCKD_00928 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AICKPCKD_00929 2.7e-48 S Domain of unknown function (DUF956)
AICKPCKD_00930 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AICKPCKD_00931 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AICKPCKD_00932 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AICKPCKD_00933 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
AICKPCKD_00934 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
AICKPCKD_00935 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AICKPCKD_00936 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AICKPCKD_00937 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
AICKPCKD_00938 4.8e-170 nusA K Participates in both transcription termination and antitermination
AICKPCKD_00939 1.4e-39 ylxR K Protein of unknown function (DUF448)
AICKPCKD_00940 6.9e-26 ylxQ J ribosomal protein
AICKPCKD_00941 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AICKPCKD_00942 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AICKPCKD_00943 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AICKPCKD_00944 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AICKPCKD_00945 1.1e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AICKPCKD_00946 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AICKPCKD_00947 1.5e-274 dnaK O Heat shock 70 kDa protein
AICKPCKD_00948 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AICKPCKD_00949 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AICKPCKD_00951 9.2e-206 glnP P ABC transporter
AICKPCKD_00952 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AICKPCKD_00953 1.5e-31
AICKPCKD_00954 2e-111 ampC V Beta-lactamase
AICKPCKD_00955 3.5e-110 cobQ S glutamine amidotransferase
AICKPCKD_00956 3.6e-220 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
AICKPCKD_00957 6.8e-86 tdk 2.7.1.21 F thymidine kinase
AICKPCKD_00958 2.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AICKPCKD_00959 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AICKPCKD_00960 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AICKPCKD_00961 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AICKPCKD_00962 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
AICKPCKD_00963 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AICKPCKD_00964 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AICKPCKD_00965 2.7e-57 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AICKPCKD_00966 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AICKPCKD_00967 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AICKPCKD_00968 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AICKPCKD_00969 3.9e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AICKPCKD_00970 4.1e-15 ywzB S Protein of unknown function (DUF1146)
AICKPCKD_00971 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AICKPCKD_00972 3.4e-167 mbl D Cell shape determining protein MreB Mrl
AICKPCKD_00973 1.2e-26 yidD S Could be involved in insertion of integral membrane proteins into the membrane
AICKPCKD_00974 1.8e-12 S Protein of unknown function (DUF2969)
AICKPCKD_00975 6.1e-187 rodA D Belongs to the SEDS family
AICKPCKD_00976 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
AICKPCKD_00977 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
AICKPCKD_00978 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
AICKPCKD_00979 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AICKPCKD_00980 4.4e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AICKPCKD_00981 2.4e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AICKPCKD_00982 5.8e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AICKPCKD_00983 1.7e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AICKPCKD_00984 3.3e-90 stp 3.1.3.16 T phosphatase
AICKPCKD_00985 3.4e-191 KLT serine threonine protein kinase
AICKPCKD_00986 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AICKPCKD_00987 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
AICKPCKD_00988 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AICKPCKD_00989 4.5e-53 asp S Asp23 family, cell envelope-related function
AICKPCKD_00990 2.8e-238 yloV S DAK2 domain fusion protein YloV
AICKPCKD_00991 3.3e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AICKPCKD_00992 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AICKPCKD_00993 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AICKPCKD_00994 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AICKPCKD_00995 4.7e-211 smc D Required for chromosome condensation and partitioning
AICKPCKD_00996 1.7e-147 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AICKPCKD_00997 7e-40 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AICKPCKD_00998 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AICKPCKD_00999 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AICKPCKD_01000 1.1e-26 ylqC S Belongs to the UPF0109 family
AICKPCKD_01001 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AICKPCKD_01002 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AICKPCKD_01003 5.7e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
AICKPCKD_01004 7e-198 yfnA E amino acid
AICKPCKD_01005 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AICKPCKD_01006 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
AICKPCKD_01007 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AICKPCKD_01008 5.3e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AICKPCKD_01009 4.9e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AICKPCKD_01010 5.6e-20 S Tetratricopeptide repeat
AICKPCKD_01011 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AICKPCKD_01012 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AICKPCKD_01013 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AICKPCKD_01014 2.3e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AICKPCKD_01015 1.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AICKPCKD_01016 5e-23 ykzG S Belongs to the UPF0356 family
AICKPCKD_01017 1.6e-24
AICKPCKD_01018 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AICKPCKD_01019 3.7e-32 1.1.1.27 C L-malate dehydrogenase activity
AICKPCKD_01020 1.7e-23 yktA S Belongs to the UPF0223 family
AICKPCKD_01021 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
AICKPCKD_01022 0.0 typA T GTP-binding protein TypA
AICKPCKD_01023 6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
AICKPCKD_01024 7e-115 manY G PTS system
AICKPCKD_01025 3.3e-148 manN G system, mannose fructose sorbose family IID component
AICKPCKD_01026 1.6e-102 ftsW D Belongs to the SEDS family
AICKPCKD_01027 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AICKPCKD_01028 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
AICKPCKD_01029 7.2e-74 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
AICKPCKD_01030 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AICKPCKD_01031 2.4e-131 ylbL T Belongs to the peptidase S16 family
AICKPCKD_01032 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
AICKPCKD_01033 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AICKPCKD_01034 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AICKPCKD_01035 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AICKPCKD_01036 3.6e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AICKPCKD_01037 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
AICKPCKD_01038 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AICKPCKD_01039 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
AICKPCKD_01040 3e-152 purD 6.3.4.13 F Belongs to the GARS family
AICKPCKD_01041 1.5e-93 S Acyltransferase family
AICKPCKD_01042 2.2e-194 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AICKPCKD_01043 3.9e-122 K LysR substrate binding domain
AICKPCKD_01045 2.2e-20
AICKPCKD_01046 6.2e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
AICKPCKD_01047 5.8e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
AICKPCKD_01048 1.4e-50 comEA L Competence protein ComEA
AICKPCKD_01049 2e-69 comEB 3.5.4.12 F ComE operon protein 2
AICKPCKD_01050 1.4e-155 comEC S Competence protein ComEC
AICKPCKD_01051 9.3e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
AICKPCKD_01052 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AICKPCKD_01053 3e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
AICKPCKD_01054 2.8e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
AICKPCKD_01055 8.1e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
AICKPCKD_01056 1.5e-228 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
AICKPCKD_01057 1.8e-36 ypmB S Protein conserved in bacteria
AICKPCKD_01058 4e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
AICKPCKD_01059 1e-235 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
AICKPCKD_01060 5.1e-56 dnaD L DnaD domain protein
AICKPCKD_01061 9.7e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AICKPCKD_01062 9.9e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AICKPCKD_01063 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AICKPCKD_01064 1.9e-93 M transferase activity, transferring glycosyl groups
AICKPCKD_01065 1.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
AICKPCKD_01066 1.3e-99 epsJ1 M Glycosyltransferase like family 2
AICKPCKD_01069 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
AICKPCKD_01070 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AICKPCKD_01071 1.8e-56 yqeY S YqeY-like protein
AICKPCKD_01073 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
AICKPCKD_01074 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AICKPCKD_01075 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AICKPCKD_01076 6.6e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AICKPCKD_01077 2.9e-276 yfmR S ABC transporter, ATP-binding protein
AICKPCKD_01078 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AICKPCKD_01079 9.4e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AICKPCKD_01080 8.6e-135 yvgN C Aldo keto reductase
AICKPCKD_01081 2.4e-35 K helix_turn_helix, mercury resistance
AICKPCKD_01082 1.3e-102 S Aldo keto reductase
AICKPCKD_01084 7.2e-79 ypmR E GDSL-like Lipase/Acylhydrolase
AICKPCKD_01085 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
AICKPCKD_01086 3.6e-24 yozE S Belongs to the UPF0346 family
AICKPCKD_01087 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AICKPCKD_01088 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AICKPCKD_01089 6.2e-85 dprA LU DNA protecting protein DprA
AICKPCKD_01090 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AICKPCKD_01091 9.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AICKPCKD_01092 5.8e-205 G PTS system Galactitol-specific IIC component
AICKPCKD_01093 2.3e-81 K Bacterial regulatory proteins, tetR family
AICKPCKD_01094 3.3e-129 yjjC V ATPases associated with a variety of cellular activities
AICKPCKD_01095 1.1e-202 M Exporter of polyketide antibiotics
AICKPCKD_01096 4e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
AICKPCKD_01097 2.3e-34 S Repeat protein
AICKPCKD_01098 5.8e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AICKPCKD_01100 1.7e-15
AICKPCKD_01103 5.9e-87 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AICKPCKD_01104 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
AICKPCKD_01105 9.1e-43 yodB K Transcriptional regulator, HxlR family
AICKPCKD_01106 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AICKPCKD_01107 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AICKPCKD_01108 9.3e-129 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AICKPCKD_01109 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
AICKPCKD_01110 2.2e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AICKPCKD_01111 8.7e-259 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
AICKPCKD_01112 4.6e-79
AICKPCKD_01113 4.2e-48 L Transposase
AICKPCKD_01114 1.9e-92
AICKPCKD_01115 2.6e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
AICKPCKD_01116 1.5e-42 hxlR K Transcriptional regulator, HxlR family
AICKPCKD_01117 2.3e-26
AICKPCKD_01118 0.0 L MobA MobL family protein
AICKPCKD_01119 6.1e-26
AICKPCKD_01120 2e-40
AICKPCKD_01121 4.3e-113 S protein conserved in bacteria
AICKPCKD_01122 1.2e-25
AICKPCKD_01123 1.1e-39 relB L Addiction module antitoxin, RelB DinJ family
AICKPCKD_01124 3.5e-132 S Fic/DOC family
AICKPCKD_01125 1.1e-83 repA S Replication initiator protein A
AICKPCKD_01126 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
AICKPCKD_01127 2.5e-211 glnP P ABC transporter
AICKPCKD_01129 6.6e-60 uspA T Universal stress protein family
AICKPCKD_01130 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
AICKPCKD_01131 1.1e-25
AICKPCKD_01132 2.9e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
AICKPCKD_01133 8e-110 puuD S peptidase C26
AICKPCKD_01134 5.2e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AICKPCKD_01135 3.1e-96 lsa S ABC transporter
AICKPCKD_01136 6.6e-90 sip L Belongs to the 'phage' integrase family
AICKPCKD_01137 1.9e-31 S ParE toxin of type II toxin-antitoxin system, parDE
AICKPCKD_01138 9.7e-23
AICKPCKD_01140 2.6e-24 S Domain of unknown function (DUF4393)
AICKPCKD_01141 2.2e-31
AICKPCKD_01142 2.6e-27 S Domain of unknown function (DUF4352)
AICKPCKD_01145 2.3e-13 S Pfam:DUF955
AICKPCKD_01146 1.6e-20 K Helix-turn-helix domain
AICKPCKD_01149 1.3e-15
AICKPCKD_01151 7.5e-15 K Cro/C1-type HTH DNA-binding domain
AICKPCKD_01154 1.3e-07 K Helix-turn-helix XRE-family like proteins
AICKPCKD_01155 4.3e-50 S DNA binding
AICKPCKD_01156 5.3e-35 S virion core protein, lumpy skin disease virus
AICKPCKD_01158 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AICKPCKD_01159 1.3e-173 malY 4.4.1.8 E Aminotransferase, class I
AICKPCKD_01160 5.3e-118 K AI-2E family transporter
AICKPCKD_01161 4e-61 EG EamA-like transporter family
AICKPCKD_01162 3.9e-76 L haloacid dehalogenase-like hydrolase
AICKPCKD_01163 5.8e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
AICKPCKD_01164 9.1e-67 1.5.1.38 S NADPH-dependent FMN reductase
AICKPCKD_01165 4e-31 tnp L MULE transposase domain
AICKPCKD_01167 8.5e-64 V HNH endonuclease
AICKPCKD_01168 7.2e-149 mepA V MATE efflux family protein
AICKPCKD_01169 6.6e-43 lsa S ABC transporter
AICKPCKD_01170 9.1e-76 3.1.21.3 V Type I restriction modification DNA specificity domain
AICKPCKD_01171 1.6e-131 L Belongs to the 'phage' integrase family
AICKPCKD_01172 1.2e-36 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
AICKPCKD_01173 6.2e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
AICKPCKD_01174 7.6e-55 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
AICKPCKD_01175 4.9e-148 D CobQ CobB MinD ParA nucleotide binding domain protein
AICKPCKD_01176 3.3e-64
AICKPCKD_01177 1.5e-46
AICKPCKD_01178 4.5e-218 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
AICKPCKD_01179 2.2e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AICKPCKD_01180 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
AICKPCKD_01181 9.3e-129 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AICKPCKD_01182 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AICKPCKD_01183 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AICKPCKD_01184 9.1e-43 yodB K Transcriptional regulator, HxlR family
AICKPCKD_01185 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
AICKPCKD_01186 5.9e-87 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AICKPCKD_01189 1.7e-15
AICKPCKD_01191 5.8e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AICKPCKD_01192 2.3e-34 S Repeat protein
AICKPCKD_01193 4e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
AICKPCKD_01194 1.1e-202 M Exporter of polyketide antibiotics
AICKPCKD_01195 3.3e-129 yjjC V ATPases associated with a variety of cellular activities
AICKPCKD_01196 2.3e-81 K Bacterial regulatory proteins, tetR family
AICKPCKD_01197 5.8e-205 G PTS system Galactitol-specific IIC component
AICKPCKD_01198 9.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AICKPCKD_01199 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AICKPCKD_01200 6.2e-85 dprA LU DNA protecting protein DprA
AICKPCKD_01201 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AICKPCKD_01202 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AICKPCKD_01203 3.6e-24 yozE S Belongs to the UPF0346 family
AICKPCKD_01204 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
AICKPCKD_01205 7.2e-79 ypmR E GDSL-like Lipase/Acylhydrolase
AICKPCKD_01207 1.3e-102 S Aldo keto reductase
AICKPCKD_01208 2.4e-35 K helix_turn_helix, mercury resistance
AICKPCKD_01209 8.6e-135 yvgN C Aldo keto reductase
AICKPCKD_01210 9.4e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AICKPCKD_01211 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AICKPCKD_01212 2.9e-276 yfmR S ABC transporter, ATP-binding protein
AICKPCKD_01213 6.6e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AICKPCKD_01214 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AICKPCKD_01215 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AICKPCKD_01216 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
AICKPCKD_01218 1.8e-56 yqeY S YqeY-like protein
AICKPCKD_01219 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AICKPCKD_01220 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
AICKPCKD_01223 1.3e-99 epsJ1 M Glycosyltransferase like family 2
AICKPCKD_01224 1.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
AICKPCKD_01225 1.9e-93 M transferase activity, transferring glycosyl groups
AICKPCKD_01226 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AICKPCKD_01227 9.9e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AICKPCKD_01228 9.7e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AICKPCKD_01229 5.1e-56 dnaD L DnaD domain protein
AICKPCKD_01230 1e-235 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
AICKPCKD_01231 4e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
AICKPCKD_01232 1.8e-36 ypmB S Protein conserved in bacteria
AICKPCKD_01233 1.5e-228 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
AICKPCKD_01234 8.1e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
AICKPCKD_01235 2.8e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
AICKPCKD_01236 3e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
AICKPCKD_01237 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AICKPCKD_01238 9.3e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
AICKPCKD_01239 1.4e-155 comEC S Competence protein ComEC
AICKPCKD_01240 2e-69 comEB 3.5.4.12 F ComE operon protein 2
AICKPCKD_01241 1.4e-50 comEA L Competence protein ComEA
AICKPCKD_01242 5.8e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
AICKPCKD_01243 6.2e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
AICKPCKD_01244 2.2e-20
AICKPCKD_01246 3.9e-122 K LysR substrate binding domain
AICKPCKD_01247 2.2e-194 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AICKPCKD_01248 1.5e-93 S Acyltransferase family
AICKPCKD_01249 3e-152 purD 6.3.4.13 F Belongs to the GARS family
AICKPCKD_01250 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
AICKPCKD_01251 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AICKPCKD_01252 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
AICKPCKD_01253 3.6e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AICKPCKD_01254 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AICKPCKD_01255 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AICKPCKD_01256 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AICKPCKD_01257 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
AICKPCKD_01258 2.4e-131 ylbL T Belongs to the peptidase S16 family
AICKPCKD_01259 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AICKPCKD_01260 7.2e-74 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
AICKPCKD_01261 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
AICKPCKD_01262 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AICKPCKD_01263 1.6e-102 ftsW D Belongs to the SEDS family
AICKPCKD_01264 3.3e-148 manN G system, mannose fructose sorbose family IID component
AICKPCKD_01265 7e-115 manY G PTS system
AICKPCKD_01266 6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
AICKPCKD_01267 0.0 typA T GTP-binding protein TypA
AICKPCKD_01268 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
AICKPCKD_01269 1.7e-23 yktA S Belongs to the UPF0223 family
AICKPCKD_01270 3.7e-32 1.1.1.27 C L-malate dehydrogenase activity
AICKPCKD_01271 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AICKPCKD_01272 1.6e-24
AICKPCKD_01273 5e-23 ykzG S Belongs to the UPF0356 family
AICKPCKD_01274 1.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AICKPCKD_01275 2.3e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AICKPCKD_01276 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AICKPCKD_01277 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AICKPCKD_01278 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AICKPCKD_01279 5.6e-20 S Tetratricopeptide repeat
AICKPCKD_01280 4.9e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AICKPCKD_01281 5.3e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AICKPCKD_01282 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AICKPCKD_01283 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
AICKPCKD_01284 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AICKPCKD_01285 7e-198 yfnA E amino acid
AICKPCKD_01286 5.7e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
AICKPCKD_01287 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AICKPCKD_01288 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AICKPCKD_01289 1.1e-26 ylqC S Belongs to the UPF0109 family
AICKPCKD_01290 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AICKPCKD_01291 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AICKPCKD_01292 7e-40 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AICKPCKD_01293 1.7e-147 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AICKPCKD_01294 4.7e-211 smc D Required for chromosome condensation and partitioning
AICKPCKD_01295 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AICKPCKD_01296 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AICKPCKD_01297 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AICKPCKD_01298 3.3e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AICKPCKD_01299 2.8e-238 yloV S DAK2 domain fusion protein YloV
AICKPCKD_01300 4.5e-53 asp S Asp23 family, cell envelope-related function
AICKPCKD_01301 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AICKPCKD_01302 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
AICKPCKD_01303 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AICKPCKD_01304 3.4e-191 KLT serine threonine protein kinase
AICKPCKD_01305 3.3e-90 stp 3.1.3.16 T phosphatase
AICKPCKD_01306 1.7e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AICKPCKD_01307 5.8e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AICKPCKD_01308 2.4e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AICKPCKD_01309 4.4e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AICKPCKD_01310 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AICKPCKD_01311 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
AICKPCKD_01312 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
AICKPCKD_01313 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
AICKPCKD_01314 6.1e-187 rodA D Belongs to the SEDS family
AICKPCKD_01315 1.8e-12 S Protein of unknown function (DUF2969)
AICKPCKD_01316 1.2e-26 yidD S Could be involved in insertion of integral membrane proteins into the membrane
AICKPCKD_01317 3.4e-167 mbl D Cell shape determining protein MreB Mrl
AICKPCKD_01318 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AICKPCKD_01319 4.1e-15 ywzB S Protein of unknown function (DUF1146)
AICKPCKD_01320 3.9e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AICKPCKD_01321 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AICKPCKD_01322 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AICKPCKD_01323 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AICKPCKD_01324 2.7e-57 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AICKPCKD_01325 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AICKPCKD_01326 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AICKPCKD_01327 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
AICKPCKD_01328 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AICKPCKD_01329 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AICKPCKD_01330 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AICKPCKD_01331 2.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AICKPCKD_01332 6.8e-86 tdk 2.7.1.21 F thymidine kinase
AICKPCKD_01333 3.6e-220 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
AICKPCKD_01334 3.5e-110 cobQ S glutamine amidotransferase
AICKPCKD_01335 2e-111 ampC V Beta-lactamase
AICKPCKD_01336 1.5e-31
AICKPCKD_01337 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AICKPCKD_01338 9.2e-206 glnP P ABC transporter
AICKPCKD_01340 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AICKPCKD_01341 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AICKPCKD_01342 1.5e-274 dnaK O Heat shock 70 kDa protein
AICKPCKD_01343 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AICKPCKD_01344 1.1e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AICKPCKD_01345 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AICKPCKD_01346 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AICKPCKD_01347 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AICKPCKD_01348 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AICKPCKD_01349 6.9e-26 ylxQ J ribosomal protein
AICKPCKD_01350 1.4e-39 ylxR K Protein of unknown function (DUF448)
AICKPCKD_01351 4.8e-170 nusA K Participates in both transcription termination and antitermination
AICKPCKD_01352 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
AICKPCKD_01353 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AICKPCKD_01354 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AICKPCKD_01355 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
AICKPCKD_01356 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
AICKPCKD_01357 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AICKPCKD_01358 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AICKPCKD_01359 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AICKPCKD_01360 2.7e-48 S Domain of unknown function (DUF956)
AICKPCKD_01361 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AICKPCKD_01363 2e-247 glnA 6.3.1.2 E glutamine synthetase
AICKPCKD_01364 1.3e-45 glnR K Transcriptional regulator
AICKPCKD_01365 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
AICKPCKD_01366 1.9e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AICKPCKD_01367 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
AICKPCKD_01368 2.7e-46 yqhL P Rhodanese-like protein
AICKPCKD_01369 4.7e-158 glk 2.7.1.2 G Glucokinase
AICKPCKD_01370 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
AICKPCKD_01371 7.4e-70 gluP 3.4.21.105 S Peptidase, S54 family
AICKPCKD_01372 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AICKPCKD_01373 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AICKPCKD_01374 3e-19 D nuclear chromosome segregation
AICKPCKD_01375 1.2e-74 yciQ P membrane protein (DUF2207)
AICKPCKD_01376 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
AICKPCKD_01377 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
AICKPCKD_01378 5.9e-27 yneF S UPF0154 protein
AICKPCKD_01379 2.2e-30 ynzC S UPF0291 protein
AICKPCKD_01380 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AICKPCKD_01381 4.2e-178 recN L May be involved in recombinational repair of damaged DNA
AICKPCKD_01382 6.6e-49 argR K Regulates arginine biosynthesis genes
AICKPCKD_01383 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
AICKPCKD_01384 4.7e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AICKPCKD_01385 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AICKPCKD_01386 1.2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AICKPCKD_01387 1.7e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AICKPCKD_01388 1.9e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AICKPCKD_01389 3.7e-46 yqhY S Asp23 family, cell envelope-related function
AICKPCKD_01390 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AICKPCKD_01391 1.3e-41 dut S dUTPase
AICKPCKD_01392 7.2e-117
AICKPCKD_01393 7.3e-105
AICKPCKD_01394 5.6e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
AICKPCKD_01395 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
AICKPCKD_01396 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AICKPCKD_01397 5e-167 arlS 2.7.13.3 T Histidine kinase
AICKPCKD_01398 3.1e-111 K response regulator
AICKPCKD_01400 8.6e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
AICKPCKD_01401 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AICKPCKD_01402 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AICKPCKD_01403 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AICKPCKD_01404 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
AICKPCKD_01405 6.9e-37
AICKPCKD_01406 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AICKPCKD_01407 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
AICKPCKD_01408 1.5e-27 yazA L GIY-YIG catalytic domain protein
AICKPCKD_01409 1.1e-93 yabB 2.1.1.223 L Methyltransferase small domain
AICKPCKD_01410 1.2e-88 plsC 2.3.1.51 I Acyltransferase
AICKPCKD_01411 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
AICKPCKD_01412 2e-57 yceD S Uncharacterized ACR, COG1399
AICKPCKD_01413 1.4e-55 ylbM S Belongs to the UPF0348 family
AICKPCKD_01414 2.2e-41 ylbM S Belongs to the UPF0348 family
AICKPCKD_01415 4.2e-82 H Nodulation protein S (NodS)
AICKPCKD_01416 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AICKPCKD_01417 7.2e-72 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
AICKPCKD_01418 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AICKPCKD_01419 1e-29 yhbY J RNA-binding protein
AICKPCKD_01420 7.9e-181 yqeH S Ribosome biogenesis GTPase YqeH
AICKPCKD_01421 2.5e-71 yqeG S HAD phosphatase, family IIIA
AICKPCKD_01422 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AICKPCKD_01423 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
AICKPCKD_01424 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AICKPCKD_01425 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AICKPCKD_01426 2.2e-107 dnaI L Primosomal protein DnaI
AICKPCKD_01427 1.6e-79 dnaB L replication initiation and membrane attachment
AICKPCKD_01428 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AICKPCKD_01429 2.1e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AICKPCKD_01430 9.5e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AICKPCKD_01431 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AICKPCKD_01432 6.7e-69 ybhL S Belongs to the BI1 family
AICKPCKD_01433 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
AICKPCKD_01434 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
AICKPCKD_01435 9e-240 sftA D Belongs to the FtsK SpoIIIE SftA family
AICKPCKD_01436 6.8e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AICKPCKD_01437 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
AICKPCKD_01438 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AICKPCKD_01439 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
AICKPCKD_01440 1.3e-72 ecsB U ABC transporter
AICKPCKD_01441 1.4e-93 ecsA V ABC transporter, ATP-binding protein
AICKPCKD_01442 5.4e-53 hit FG histidine triad
AICKPCKD_01444 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AICKPCKD_01445 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
AICKPCKD_01446 2e-21 yheA S Belongs to the UPF0342 family
AICKPCKD_01447 1e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AICKPCKD_01449 2.1e-88 ykuT M mechanosensitive ion channel
AICKPCKD_01450 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AICKPCKD_01451 1.5e-60 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AICKPCKD_01452 1.5e-45 ykuL S CBS domain
AICKPCKD_01453 5.7e-119 gla U Major intrinsic protein
AICKPCKD_01454 2.7e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AICKPCKD_01455 9.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
AICKPCKD_01456 1.5e-230 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AICKPCKD_01457 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
AICKPCKD_01458 2.3e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
AICKPCKD_01459 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AICKPCKD_01460 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
AICKPCKD_01461 1.5e-63 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AICKPCKD_01462 7.9e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AICKPCKD_01463 1.8e-194 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AICKPCKD_01464 1.4e-98 IQ reductase
AICKPCKD_01465 6.5e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
AICKPCKD_01466 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AICKPCKD_01467 6.4e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AICKPCKD_01468 4.2e-61 marR K Transcriptional regulator, MarR family
AICKPCKD_01469 1.3e-65 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AICKPCKD_01470 3e-36
AICKPCKD_01472 3.3e-182 S Protein of unknown function DUF262
AICKPCKD_01473 5.1e-193 pepV 3.5.1.18 E dipeptidase PepV
AICKPCKD_01474 1.2e-80 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AICKPCKD_01475 1.1e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AICKPCKD_01476 8.3e-187 ytgP S Polysaccharide biosynthesis protein
AICKPCKD_01477 9.7e-194 cycA E Amino acid permease
AICKPCKD_01478 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
AICKPCKD_01479 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AICKPCKD_01480 4.1e-56 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
AICKPCKD_01483 7.1e-17 tnp L Transposase IS66 family
AICKPCKD_01484 1.7e-32 P Heavy-metal-associated domain
AICKPCKD_01485 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
AICKPCKD_01486 1.8e-20 L PFAM transposase IS3 IS911 family protein
AICKPCKD_01487 2.7e-81 L Integrase core domain
AICKPCKD_01488 2.6e-129 EGP Major Facilitator Superfamily
AICKPCKD_01489 1.4e-98 EGP Major Facilitator Superfamily
AICKPCKD_01490 1.3e-72 K Transcriptional regulator, LysR family
AICKPCKD_01491 1.6e-138 G Xylose isomerase-like TIM barrel
AICKPCKD_01492 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
AICKPCKD_01493 1.6e-217 1.3.5.4 C FAD binding domain
AICKPCKD_01494 6.5e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AICKPCKD_01495 3.8e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
AICKPCKD_01496 1.4e-142 xerS L Phage integrase family
AICKPCKD_01500 1.6e-90 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
AICKPCKD_01501 1.4e-70 ptp3 3.1.3.48 T Tyrosine phosphatase family
AICKPCKD_01502 2.1e-63 desR K helix_turn_helix, Lux Regulon
AICKPCKD_01503 5.4e-57 salK 2.7.13.3 T Histidine kinase
AICKPCKD_01504 1.9e-53 yvfS V ABC-2 type transporter
AICKPCKD_01505 1.5e-78 yvfR V ABC transporter
AICKPCKD_01507 3.4e-10 S Protein of unknown function (DUF805)
AICKPCKD_01508 1.8e-08 K transcriptional
AICKPCKD_01509 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AICKPCKD_01510 2.3e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
AICKPCKD_01511 1.5e-29
AICKPCKD_01512 8.7e-63 sip L Belongs to the 'phage' integrase family
AICKPCKD_01513 6.5e-07
AICKPCKD_01515 5.4e-19 Z012_06740 S Fic/DOC family
AICKPCKD_01516 1.6e-28
AICKPCKD_01517 1.2e-61 gepA K Protein of unknown function (DUF4065)
AICKPCKD_01518 7.5e-08
AICKPCKD_01519 5.7e-66 D nuclear chromosome segregation
AICKPCKD_01521 4.8e-78 S Fic/DOC family
AICKPCKD_01523 1e-10
AICKPCKD_01525 2.3e-61 ruvB 3.6.4.12 L four-way junction helicase activity
AICKPCKD_01529 1.9e-11 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
AICKPCKD_01530 7.5e-20
AICKPCKD_01535 1.5e-08
AICKPCKD_01540 1e-20 S Replication initiator protein A (RepA) N-terminus
AICKPCKD_01542 1.4e-09 S Arc-like DNA binding domain
AICKPCKD_01547 6.6e-11 3.4.21.88 K Peptidase S24-like
AICKPCKD_01548 2.2e-11 S sequence-specific DNA binding
AICKPCKD_01549 5.1e-86 S Fic/DOC family
AICKPCKD_01552 4.5e-198 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
AICKPCKD_01554 1.9e-39
AICKPCKD_01556 8.2e-16
AICKPCKD_01557 2.1e-112 rssA S Phospholipase, patatin family
AICKPCKD_01558 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AICKPCKD_01559 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
AICKPCKD_01560 3.3e-45 S VIT family
AICKPCKD_01561 9.4e-240 sufB O assembly protein SufB
AICKPCKD_01562 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
AICKPCKD_01563 3.3e-148 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AICKPCKD_01564 5.6e-143 sufD O FeS assembly protein SufD
AICKPCKD_01565 1.8e-115 sufC O FeS assembly ATPase SufC
AICKPCKD_01566 3.2e-223 E ABC transporter, substratebinding protein
AICKPCKD_01568 7.7e-20 S protein encoded in hypervariable junctions of pilus gene clusters
AICKPCKD_01569 2.5e-27 K Helix-turn-helix XRE-family like proteins
AICKPCKD_01571 9.6e-47 V ABC-2 family transporter protein
AICKPCKD_01572 3.3e-73 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
AICKPCKD_01573 1.7e-105 2.7.13.3 T His Kinase A (phosphoacceptor) domain
AICKPCKD_01574 8.8e-90 KT Transcriptional regulatory protein, C terminal
AICKPCKD_01575 1.4e-58 spaC2 V Lanthionine synthetase C-like protein
AICKPCKD_01576 4.3e-184 spaT V ATPases associated with a variety of cellular activities
AICKPCKD_01577 2.6e-207 spaB S Lantibiotic dehydratase, C terminus
AICKPCKD_01579 2.5e-136 pfoS S Phosphotransferase system, EIIC
AICKPCKD_01580 5.5e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
AICKPCKD_01581 9.1e-63 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
AICKPCKD_01582 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
AICKPCKD_01583 1.4e-136 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
AICKPCKD_01584 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
AICKPCKD_01585 4.5e-43 gutM K Glucitol operon activator protein (GutM)
AICKPCKD_01586 5.8e-104 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
AICKPCKD_01587 4e-110 IQ NAD dependent epimerase/dehydratase family
AICKPCKD_01588 4.7e-163 ytbD EGP Major facilitator Superfamily
AICKPCKD_01589 3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
AICKPCKD_01590 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AICKPCKD_01591 1.2e-189 tonB M YSIRK type signal peptide
AICKPCKD_01592 2.2e-263 fbp 3.1.3.11 G phosphatase activity
AICKPCKD_01593 1.9e-70 xerD L Phage integrase, N-terminal SAM-like domain
AICKPCKD_01596 2e-86 mesE M Transport protein ComB
AICKPCKD_01597 4e-282 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AICKPCKD_01605 1.9e-56 K LytTr DNA-binding domain
AICKPCKD_01606 8.8e-59 2.7.13.3 T GHKL domain
AICKPCKD_01611 1.1e-16
AICKPCKD_01612 1.2e-12
AICKPCKD_01614 4.2e-08
AICKPCKD_01615 4.2e-37 blpT
AICKPCKD_01616 1.8e-14
AICKPCKD_01618 7.8e-187 mtnE 2.6.1.83 E Aminotransferase
AICKPCKD_01619 6.5e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
AICKPCKD_01620 1.3e-66 S Protein of unknown function (DUF1440)
AICKPCKD_01621 7.7e-41 S Iron-sulfur cluster assembly protein
AICKPCKD_01622 5.5e-113 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
AICKPCKD_01623 1.5e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
AICKPCKD_01624 6.6e-207 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AICKPCKD_01625 3.9e-154 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AICKPCKD_01626 2.3e-64 G Xylose isomerase domain protein TIM barrel
AICKPCKD_01627 3.8e-54 ndk 2.7.4.6 F Belongs to the NDK family
AICKPCKD_01628 1.2e-88 nanK GK ROK family
AICKPCKD_01629 3.3e-126 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
AICKPCKD_01630 1.6e-91 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AICKPCKD_01631 7.8e-77 K Helix-turn-helix domain, rpiR family
AICKPCKD_01632 3.5e-61 yphA GM NAD dependent epimerase/dehydratase family
AICKPCKD_01633 3.1e-217 yjeM E Amino Acid
AICKPCKD_01635 1.2e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AICKPCKD_01636 1e-231 tetP J elongation factor G
AICKPCKD_01637 1.1e-278 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AICKPCKD_01638 1.3e-87 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AICKPCKD_01639 1.1e-166 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
AICKPCKD_01640 2.8e-119 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
AICKPCKD_01641 2.4e-181 gatC G PTS system sugar-specific permease component
AICKPCKD_01642 2e-35 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
AICKPCKD_01643 2.7e-39 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AICKPCKD_01644 2.2e-60 K DeoR C terminal sensor domain
AICKPCKD_01645 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
AICKPCKD_01646 4.8e-64 S Fic/DOC family
AICKPCKD_01647 8.3e-47 S Fic/DOC family
AICKPCKD_01648 1.9e-09 yokH G regulation of fungal-type cell wall biogenesis
AICKPCKD_01649 9.4e-109 L Initiator Replication protein
AICKPCKD_01650 3.9e-38 S Replication initiator protein A (RepA) N-terminus
AICKPCKD_01651 3.8e-172 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AICKPCKD_01652 6e-205 G Pts system
AICKPCKD_01653 2.1e-64 licT K transcriptional antiterminator
AICKPCKD_01654 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
AICKPCKD_01656 1.8e-33
AICKPCKD_01657 6.9e-08 S CAAX protease self-immunity
AICKPCKD_01658 0.0 pepN 3.4.11.2 E aminopeptidase
AICKPCKD_01659 2.1e-44 2.7.13.3 T protein histidine kinase activity
AICKPCKD_01660 1.3e-35 agrA KT Response regulator of the LytR AlgR family
AICKPCKD_01661 9.8e-21 M domain protein
AICKPCKD_01665 3.6e-09
AICKPCKD_01666 3.4e-16
AICKPCKD_01670 1.8e-124 yvgN C Aldo keto reductase
AICKPCKD_01671 3.9e-105 yraQ S Predicted permease
AICKPCKD_01672 1.1e-62 yeeE S Sulphur transport
AICKPCKD_01673 1.6e-16 yeeD O Belongs to the sulfur carrier protein TusA family
AICKPCKD_01674 2.2e-116 ynjE 2.8.1.11 P Rhodanese Homology Domain
AICKPCKD_01676 4.3e-235 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
AICKPCKD_01677 7.1e-26 S Psort location Cytoplasmic, score
AICKPCKD_01678 7.6e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
AICKPCKD_01679 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
AICKPCKD_01680 1.6e-73 prdD S An automated process has identified a potential problem with this gene model
AICKPCKD_01681 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
AICKPCKD_01682 7e-144 5.1.1.4 E Proline racemase
AICKPCKD_01683 4.4e-94 XK27_00825 S Sulfite exporter TauE/SafE
AICKPCKD_01684 4.5e-222 ybeC E amino acid
AICKPCKD_01685 1.2e-48 yedF O Belongs to the sulfur carrier protein TusA family
AICKPCKD_01686 4.5e-08 S Protein of unknown function (DUF3343)
AICKPCKD_01687 4.8e-138 selB J Elongation factor SelB, winged helix
AICKPCKD_01688 5.1e-111 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
AICKPCKD_01689 2e-109 selA 2.9.1.1 J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
AICKPCKD_01690 9e-29 yitW S Iron-sulfur cluster assembly protein
AICKPCKD_01691 2.4e-176 rnfC C RnfC Barrel sandwich hybrid domain
AICKPCKD_01692 9.2e-101 selD 2.7.9.3 E AIR synthase related protein, C-terminal domain
AICKPCKD_01693 8.3e-149 yedE S Sulphur transport
AICKPCKD_01694 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
AICKPCKD_01695 4.7e-35 L Helix-turn-helix domain
AICKPCKD_01696 3.9e-68 tra L EVIDENCE BY HOMOLOGY BIO14.04 Transposon related functions. BELONGS TO THE IS30 FAMILY OF TRANSPOSASE. There are 15 such elements in the chromosome
AICKPCKD_01697 4.6e-18 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
AICKPCKD_01698 7.2e-58 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
AICKPCKD_01700 3e-56 S COG NOG19168 non supervised orthologous group
AICKPCKD_01701 1.3e-180 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
AICKPCKD_01702 6.4e-50 S Membrane
AICKPCKD_01703 2.2e-76 rhaR K helix_turn_helix, arabinose operon control protein
AICKPCKD_01704 1.5e-188 iolF EGP Major facilitator Superfamily
AICKPCKD_01705 1.7e-215 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
AICKPCKD_01706 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
AICKPCKD_01707 1.8e-218 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
AICKPCKD_01708 1.5e-109 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
AICKPCKD_01710 4.1e-189 XK27_11280 S Psort location CytoplasmicMembrane, score
AICKPCKD_01711 6.1e-11 L Plasmid pRiA4b ORF-3-like protein
AICKPCKD_01712 1.2e-105 L Belongs to the 'phage' integrase family
AICKPCKD_01713 5.6e-18 3.1.21.3 V Type I restriction modification DNA specificity domain
AICKPCKD_01714 6.6e-60 hsdM 2.1.1.72 V type I restriction-modification system
AICKPCKD_01716 2.3e-125 L T/G mismatch-specific endonuclease activity
AICKPCKD_01717 4.5e-20 L T/G mismatch-specific endonuclease activity
AICKPCKD_01721 4.7e-07
AICKPCKD_01722 3.9e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
AICKPCKD_01723 1.7e-54 rplI J Binds to the 23S rRNA
AICKPCKD_01724 1.3e-204 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
AICKPCKD_01725 5.3e-64 C FMN binding
AICKPCKD_01726 1.6e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AICKPCKD_01728 8.7e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AICKPCKD_01729 3.5e-59 ykhA 3.1.2.20 I Thioesterase superfamily
AICKPCKD_01730 5.6e-10 S CAAX protease self-immunity
AICKPCKD_01731 2.8e-81 S Belongs to the UPF0246 family
AICKPCKD_01732 1.6e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
AICKPCKD_01733 9.3e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
AICKPCKD_01734 3.7e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
AICKPCKD_01735 4.5e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
AICKPCKD_01736 3.8e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
AICKPCKD_01737 2.2e-56 3.1.3.48 K Transcriptional regulator
AICKPCKD_01738 1.2e-197 1.3.5.4 C FMN_bind
AICKPCKD_01739 6.5e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
AICKPCKD_01740 2e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
AICKPCKD_01741 2.8e-139 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AICKPCKD_01742 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
AICKPCKD_01743 2e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
AICKPCKD_01744 2.1e-106 G PTS system sorbose-specific iic component
AICKPCKD_01745 2.4e-123 G PTS system mannose/fructose/sorbose family IID component
AICKPCKD_01746 2e-39 2.7.1.191 G PTS system fructose IIA component
AICKPCKD_01747 4.2e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
AICKPCKD_01748 5.3e-112 lacI3 K helix_turn _helix lactose operon repressor
AICKPCKD_01749 2.8e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
AICKPCKD_01750 1.5e-76 hchA S intracellular protease amidase
AICKPCKD_01751 1.2e-21 K transcriptional regulator
AICKPCKD_01752 5.6e-150 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AICKPCKD_01753 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
AICKPCKD_01754 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
AICKPCKD_01755 1.5e-251 ctpA 3.6.3.54 P P-type ATPase
AICKPCKD_01756 5e-66 pgm3 G phosphoglycerate mutase family
AICKPCKD_01757 8.2e-55 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
AICKPCKD_01758 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AICKPCKD_01759 9.1e-219 yifK E Amino acid permease
AICKPCKD_01760 1.4e-202 oppA E ABC transporter, substratebinding protein
AICKPCKD_01761 1e-141 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
AICKPCKD_01762 5.8e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
AICKPCKD_01763 1.3e-180 oppD P Belongs to the ABC transporter superfamily
AICKPCKD_01764 3.7e-155 oppF P Belongs to the ABC transporter superfamily
AICKPCKD_01765 1.2e-15 psiE S Phosphate-starvation-inducible E
AICKPCKD_01766 2.2e-209 mmuP E amino acid
AICKPCKD_01767 7.6e-113 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
AICKPCKD_01768 4.5e-39 K LytTr DNA-binding domain
AICKPCKD_01769 2.5e-16 S Protein of unknown function (DUF3021)
AICKPCKD_01770 1.2e-150 yfeX P Peroxidase
AICKPCKD_01771 1.8e-30 tetR K Transcriptional regulator C-terminal region
AICKPCKD_01772 3.1e-47 S Short repeat of unknown function (DUF308)
AICKPCKD_01773 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AICKPCKD_01774 6.3e-120 oxlT P Major Facilitator Superfamily
AICKPCKD_01775 2e-67 ybbL S ABC transporter
AICKPCKD_01776 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
AICKPCKD_01777 4.2e-43 ytcD K HxlR-like helix-turn-helix
AICKPCKD_01778 6.9e-121 ytbE S reductase
AICKPCKD_01779 7.5e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AICKPCKD_01781 6.4e-96 XK27_06785 V ABC transporter, ATP-binding protein
AICKPCKD_01782 1.2e-253 XK27_06780 V ABC transporter permease
AICKPCKD_01784 5.1e-42 wecD K Acetyltransferase GNAT Family
AICKPCKD_01785 3.9e-47 hmpT S ECF-type riboflavin transporter, S component
AICKPCKD_01786 2.1e-69 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
AICKPCKD_01787 1.7e-09 yvaZ S Protein of unknown function (DUF1648)
AICKPCKD_01788 1.7e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
AICKPCKD_01789 1.3e-284 pepO 3.4.24.71 O Peptidase family M13
AICKPCKD_01790 7.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
AICKPCKD_01791 6.9e-54 K Transcriptional regulator C-terminal region
AICKPCKD_01792 1.6e-55 jag S R3H domain protein
AICKPCKD_01793 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
AICKPCKD_01794 2e-31 azlD S Branched-chain amino acid transport protein (AzlD)
AICKPCKD_01795 2e-76 azlC E branched-chain amino acid
AICKPCKD_01796 5.5e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
AICKPCKD_01797 9.4e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
AICKPCKD_01798 4.7e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
AICKPCKD_01799 3.8e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
AICKPCKD_01800 1.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
AICKPCKD_01801 3.1e-75 XK27_02070 S Nitroreductase family
AICKPCKD_01802 1.7e-111 endA F DNA RNA non-specific endonuclease
AICKPCKD_01804 5.9e-210 brnQ U Component of the transport system for branched-chain amino acids
AICKPCKD_01805 6.5e-61 K Bacterial regulatory proteins, tetR family
AICKPCKD_01806 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
AICKPCKD_01807 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
AICKPCKD_01808 9.5e-69 dhaL 2.7.1.121 S Dak2
AICKPCKD_01809 4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
AICKPCKD_01810 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AICKPCKD_01811 9.8e-177 yjcE P Sodium proton antiporter
AICKPCKD_01812 4e-210 mtlR K Mga helix-turn-helix domain
AICKPCKD_01813 5.9e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AICKPCKD_01814 6.1e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
AICKPCKD_01815 3.2e-29 ponA V the current gene model (or a revised gene model) may contain a frame shift
AICKPCKD_01817 4.5e-102 tcyB E ABC transporter
AICKPCKD_01818 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AICKPCKD_01819 1.3e-95 tcyA ET Belongs to the bacterial solute-binding protein 3 family
AICKPCKD_01820 1.6e-38 K Transcriptional regulator
AICKPCKD_01821 2.2e-107 terC P Integral membrane protein TerC family
AICKPCKD_01822 4.2e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
AICKPCKD_01823 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AICKPCKD_01824 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
AICKPCKD_01825 1.1e-41 gntR1 K Transcriptional regulator, GntR family
AICKPCKD_01826 8e-96 V ABC transporter, ATP-binding protein
AICKPCKD_01827 2.5e-08
AICKPCKD_01828 1.1e-39 ybjQ S Belongs to the UPF0145 family
AICKPCKD_01829 4.7e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
AICKPCKD_01830 1.5e-96 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AICKPCKD_01831 1e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AICKPCKD_01832 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AICKPCKD_01833 1.1e-33
AICKPCKD_01834 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
AICKPCKD_01835 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
AICKPCKD_01836 2.3e-63 srtA 3.4.22.70 M sortase family
AICKPCKD_01838 1.8e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
AICKPCKD_01839 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
AICKPCKD_01841 4.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AICKPCKD_01842 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
AICKPCKD_01843 1.3e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AICKPCKD_01844 9.3e-161 camS S sex pheromone
AICKPCKD_01845 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AICKPCKD_01846 4e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AICKPCKD_01847 2.8e-255 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AICKPCKD_01848 9.8e-146 yegS 2.7.1.107 G Lipid kinase
AICKPCKD_01849 9.9e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AICKPCKD_01850 1.4e-121 L Mrr N-terminal domain
AICKPCKD_01851 1.3e-17
AICKPCKD_01852 1.3e-75 K phage regulatory protein, rha family
AICKPCKD_01853 3e-22
AICKPCKD_01854 4.1e-16
AICKPCKD_01855 9.1e-78 L AAA domain
AICKPCKD_01856 5.4e-19 K Cro/C1-type HTH DNA-binding domain
AICKPCKD_01857 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
AICKPCKD_01858 1.3e-162 hsdM 2.1.1.72 V cog cog0286
AICKPCKD_01859 3.2e-37 hsdM 2.1.1.72 V type I restriction-modification system
AICKPCKD_01860 4.5e-86 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain protein
AICKPCKD_01861 8.3e-126 S Bacteriophage abortive infection AbiH
AICKPCKD_01864 1.6e-174 spoVK O ATPase family associated with various cellular activities (AAA)
AICKPCKD_01865 3.5e-50 K Cro/C1-type HTH DNA-binding domain
AICKPCKD_01867 5.2e-65 S Acetyltransferase (GNAT) domain
AICKPCKD_01868 5.1e-72 ywlG S Belongs to the UPF0340 family
AICKPCKD_01869 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
AICKPCKD_01870 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AICKPCKD_01871 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AICKPCKD_01872 1.4e-176 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
AICKPCKD_01873 2e-14 ybaN S Protein of unknown function (DUF454)
AICKPCKD_01874 3.9e-238 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
AICKPCKD_01875 7.2e-200 frdC 1.3.5.4 C FAD binding domain
AICKPCKD_01876 5.3e-206 yflS P Sodium:sulfate symporter transmembrane region
AICKPCKD_01877 4.6e-36 yncA 2.3.1.79 S Maltose acetyltransferase
AICKPCKD_01878 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AICKPCKD_01879 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
AICKPCKD_01880 1.9e-95 ypuA S Protein of unknown function (DUF1002)
AICKPCKD_01882 1.4e-113 3.2.1.18 GH33 M Rib/alpha-like repeat
AICKPCKD_01883 2.1e-116 3.2.1.18 GH33 M Rib/alpha-like repeat
AICKPCKD_01884 8.1e-44 K Copper transport repressor CopY TcrY
AICKPCKD_01885 6.1e-60 T Belongs to the universal stress protein A family
AICKPCKD_01886 5.9e-41 K Bacterial regulatory proteins, tetR family
AICKPCKD_01887 1.1e-56 K transcriptional
AICKPCKD_01888 1.8e-71 mleR K LysR family
AICKPCKD_01889 4.9e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
AICKPCKD_01890 1.7e-126 mleP S Sodium Bile acid symporter family
AICKPCKD_01891 5.5e-64 S ECF transporter, substrate-specific component
AICKPCKD_01892 1.6e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
AICKPCKD_01893 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AICKPCKD_01894 6.3e-193 pbuX F xanthine permease
AICKPCKD_01895 1.7e-35 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
AICKPCKD_01896 9e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
AICKPCKD_01897 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
AICKPCKD_01898 1.3e-116 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AICKPCKD_01899 1.3e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
AICKPCKD_01900 1.6e-159 mgtE P Acts as a magnesium transporter
AICKPCKD_01902 1.7e-40
AICKPCKD_01903 9.7e-35 K GNAT family
AICKPCKD_01904 6.4e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
AICKPCKD_01905 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
AICKPCKD_01906 4.9e-42 O ADP-ribosylglycohydrolase
AICKPCKD_01907 3.6e-220 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
AICKPCKD_01908 2.8e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AICKPCKD_01909 4.2e-161 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AICKPCKD_01910 4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
AICKPCKD_01911 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
AICKPCKD_01912 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AICKPCKD_01913 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
AICKPCKD_01914 2e-24 S Domain of unknown function (DUF4828)
AICKPCKD_01915 7e-128 mocA S Oxidoreductase
AICKPCKD_01916 5.2e-160 yfmL L DEAD DEAH box helicase
AICKPCKD_01917 2e-20 S Domain of unknown function (DUF3284)
AICKPCKD_01919 2.3e-279 kup P Transport of potassium into the cell
AICKPCKD_01920 4.2e-101 malR K Transcriptional regulator, LacI family
AICKPCKD_01921 4.3e-213 malT G Transporter, major facilitator family protein
AICKPCKD_01922 2.9e-78 galM 5.1.3.3 G Aldose 1-epimerase
AICKPCKD_01923 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
AICKPCKD_01924 4.9e-85 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
AICKPCKD_01925 3e-266 E Amino acid permease
AICKPCKD_01926 6.7e-181 pepS E Thermophilic metalloprotease (M29)
AICKPCKD_01927 9.3e-169 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
AICKPCKD_01928 1.1e-70 K Sugar-specific transcriptional regulator TrmB
AICKPCKD_01929 1.7e-122 S Sulfite exporter TauE/SafE
AICKPCKD_01930 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
AICKPCKD_01931 0.0 S Bacterial membrane protein YfhO
AICKPCKD_01932 8.7e-53 gtcA S Teichoic acid glycosylation protein
AICKPCKD_01933 5.1e-54 fld C Flavodoxin
AICKPCKD_01934 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
AICKPCKD_01935 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AICKPCKD_01936 1.8e-12 mltD CBM50 M Lysin motif
AICKPCKD_01937 2.9e-93 yihY S Belongs to the UPF0761 family
AICKPCKD_01938 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
AICKPCKD_01939 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AICKPCKD_01940 7.8e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AICKPCKD_01941 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AICKPCKD_01942 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AICKPCKD_01943 1.9e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AICKPCKD_01944 1.1e-40 yabR J RNA binding
AICKPCKD_01945 1e-21 divIC D Septum formation initiator
AICKPCKD_01946 3.6e-31 yabO J S4 domain protein
AICKPCKD_01947 2.8e-139 yabM S Polysaccharide biosynthesis protein
AICKPCKD_01948 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AICKPCKD_01949 2.2e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AICKPCKD_01950 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AICKPCKD_01951 2.5e-86 S (CBS) domain
AICKPCKD_01952 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AICKPCKD_01953 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AICKPCKD_01954 7.2e-53 perR P Belongs to the Fur family
AICKPCKD_01955 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
AICKPCKD_01956 1.2e-106 sbcC L Putative exonuclease SbcCD, C subunit
AICKPCKD_01957 9.8e-115 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AICKPCKD_01958 6.8e-35 M LysM domain protein
AICKPCKD_01959 1.1e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AICKPCKD_01960 1.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AICKPCKD_01961 1.9e-33 ygfC K transcriptional regulator (TetR family)
AICKPCKD_01962 2.6e-109 hrtB V ABC transporter permease
AICKPCKD_01963 4e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
AICKPCKD_01964 0.0 helD 3.6.4.12 L DNA helicase
AICKPCKD_01965 3.1e-246 yjbQ P TrkA C-terminal domain protein
AICKPCKD_01966 5.7e-28
AICKPCKD_01967 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
AICKPCKD_01968 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AICKPCKD_01969 2.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AICKPCKD_01970 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AICKPCKD_01971 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AICKPCKD_01972 1.8e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AICKPCKD_01973 4.8e-53 rplQ J Ribosomal protein L17
AICKPCKD_01974 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AICKPCKD_01975 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AICKPCKD_01976 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AICKPCKD_01977 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
AICKPCKD_01978 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AICKPCKD_01979 5.8e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AICKPCKD_01980 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AICKPCKD_01981 1e-67 rplO J Binds to the 23S rRNA
AICKPCKD_01982 2.1e-22 rpmD J Ribosomal protein L30
AICKPCKD_01983 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AICKPCKD_01984 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AICKPCKD_01985 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AICKPCKD_01986 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AICKPCKD_01987 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AICKPCKD_01988 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AICKPCKD_01989 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AICKPCKD_01990 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AICKPCKD_01991 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AICKPCKD_01992 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
AICKPCKD_01993 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AICKPCKD_01994 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AICKPCKD_01995 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AICKPCKD_01996 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AICKPCKD_01997 4.1e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AICKPCKD_01998 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AICKPCKD_01999 1e-100 rplD J Forms part of the polypeptide exit tunnel
AICKPCKD_02000 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AICKPCKD_02001 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
AICKPCKD_02002 4.3e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AICKPCKD_02003 2.5e-78 K rpiR family
AICKPCKD_02004 2.6e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
AICKPCKD_02005 2.1e-145 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
AICKPCKD_02006 6.5e-21 K Acetyltransferase (GNAT) domain
AICKPCKD_02007 9e-184 steT E amino acid
AICKPCKD_02008 9.6e-78 glnP P ABC transporter permease
AICKPCKD_02009 1.2e-85 gluC P ABC transporter permease
AICKPCKD_02010 1.9e-99 glnH ET ABC transporter
AICKPCKD_02011 3.7e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AICKPCKD_02012 1.3e-09
AICKPCKD_02013 5e-98
AICKPCKD_02014 3e-12 3.2.1.14 GH18
AICKPCKD_02015 9.2e-53 zur P Belongs to the Fur family
AICKPCKD_02016 6.3e-212 yfnA E Amino Acid
AICKPCKD_02017 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AICKPCKD_02018 0.0 L Helicase C-terminal domain protein
AICKPCKD_02019 2.7e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
AICKPCKD_02020 2.1e-180 yhdP S Transporter associated domain
AICKPCKD_02021 4.8e-26
AICKPCKD_02022 3.7e-75 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AICKPCKD_02023 9.6e-132 bacI V MacB-like periplasmic core domain
AICKPCKD_02024 9.6e-97 V ABC transporter
AICKPCKD_02025 2.2e-63 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AICKPCKD_02026 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
AICKPCKD_02027 3.6e-140 V MatE
AICKPCKD_02028 1.6e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AICKPCKD_02029 5e-87 S Alpha beta hydrolase
AICKPCKD_02030 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AICKPCKD_02031 2.5e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AICKPCKD_02032 4.6e-112 argE 3.5.1.18 E Peptidase dimerisation domain
AICKPCKD_02033 5e-102 IQ Enoyl-(Acyl carrier protein) reductase
AICKPCKD_02034 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
AICKPCKD_02035 4.3e-54 queT S QueT transporter
AICKPCKD_02037 7.3e-65 degV S Uncharacterised protein, DegV family COG1307
AICKPCKD_02038 2e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AICKPCKD_02039 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AICKPCKD_02040 1.9e-34 trxA O Belongs to the thioredoxin family
AICKPCKD_02041 4.9e-87 S Sucrose-6F-phosphate phosphohydrolase
AICKPCKD_02042 3.2e-121 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AICKPCKD_02043 2.8e-49 S Threonine/Serine exporter, ThrE
AICKPCKD_02044 1.3e-81 thrE S Putative threonine/serine exporter
AICKPCKD_02045 3.1e-27 cspC K Cold shock protein
AICKPCKD_02046 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
AICKPCKD_02047 2.9e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
AICKPCKD_02048 5.4e-23
AICKPCKD_02049 1.2e-58 3.6.1.27 I phosphatase
AICKPCKD_02050 2.4e-25
AICKPCKD_02051 2.4e-65 I alpha/beta hydrolase fold
AICKPCKD_02052 1.3e-38 azlD S branched-chain amino acid
AICKPCKD_02053 1.1e-104 azlC E AzlC protein
AICKPCKD_02054 1.6e-17
AICKPCKD_02055 1.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
AICKPCKD_02056 3.8e-99 V domain protein
AICKPCKD_02057 3.9e-10
AICKPCKD_02061 7.7e-148 XK27_08315 M Sulfatase
AICKPCKD_02062 3.2e-129 S Bacterial membrane protein YfhO
AICKPCKD_02063 8.8e-102 S Bacterial membrane protein, YfhO
AICKPCKD_02064 2.5e-72 S Bacterial membrane protein, YfhO
AICKPCKD_02065 3.6e-14
AICKPCKD_02066 1.5e-55 S Psort location CytoplasmicMembrane, score
AICKPCKD_02067 3.3e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
AICKPCKD_02068 1.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
AICKPCKD_02069 2.7e-156 XK27_09615 S reductase
AICKPCKD_02070 5.4e-67 XK27_09620 S NADPH-dependent FMN reductase
AICKPCKD_02071 4.7e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AICKPCKD_02072 1.2e-160 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AICKPCKD_02073 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
AICKPCKD_02074 2.1e-30 gtcA S Teichoic acid glycosylation protein
AICKPCKD_02075 5e-115 rfbJ M Glycosyl transferase family 2
AICKPCKD_02076 8.5e-34 S Predicted membrane protein (DUF2142)
AICKPCKD_02077 3.3e-82
AICKPCKD_02078 7.6e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
AICKPCKD_02079 1e-133 coaA 2.7.1.33 F Pantothenic acid kinase
AICKPCKD_02080 6.3e-44 E GDSL-like Lipase/Acylhydrolase
AICKPCKD_02081 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AICKPCKD_02082 1.9e-190 glnPH2 P ABC transporter permease
AICKPCKD_02083 2.5e-214 yjeM E Amino Acid
AICKPCKD_02084 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
AICKPCKD_02085 8.1e-136 tetA EGP Major facilitator Superfamily
AICKPCKD_02087 2e-69 rny D Peptidase family M23
AICKPCKD_02088 9.8e-74 M transferase activity, transferring glycosyl groups
AICKPCKD_02089 5.8e-57 cps3F
AICKPCKD_02090 2e-160 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
AICKPCKD_02091 3.7e-65 S Glycosyltransferase like family 2
AICKPCKD_02092 1.6e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
AICKPCKD_02093 1.8e-95 M Core-2/I-Branching enzyme
AICKPCKD_02094 2e-91 rfbP M Bacterial sugar transferase
AICKPCKD_02095 1.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AICKPCKD_02096 1.6e-111 ywqE 3.1.3.48 GM PHP domain protein
AICKPCKD_02097 9.3e-82 ywqD 2.7.10.1 D Capsular exopolysaccharide family
AICKPCKD_02098 2.6e-77 epsB M biosynthesis protein
AICKPCKD_02099 3.2e-214 ugd 1.1.1.22 M UDP binding domain
AICKPCKD_02100 1e-42
AICKPCKD_02101 3e-41 S Acyltransferase family
AICKPCKD_02102 8e-130 S Membrane protein involved in the export of O-antigen and teichoic acid
AICKPCKD_02103 5.8e-26 S Acetyltransferase (Isoleucine patch superfamily)
AICKPCKD_02104 1.3e-42 M Glycosyltransferase like family 2
AICKPCKD_02106 7.3e-46 S Glycosyl transferase family 2
AICKPCKD_02107 4.7e-143 M Glycosyl transferase family 2
AICKPCKD_02108 6.8e-47 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
AICKPCKD_02109 1.9e-120 G Glycosyltransferase Family 4
AICKPCKD_02110 9.7e-174 rgpAc GT4 M Domain of unknown function (DUF1972)
AICKPCKD_02112 2e-80 S response to antibiotic
AICKPCKD_02113 9.8e-27 S zinc-ribbon domain
AICKPCKD_02114 9.4e-118 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
AICKPCKD_02115 9.9e-128 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AICKPCKD_02116 6.2e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AICKPCKD_02117 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
AICKPCKD_02118 1.2e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AICKPCKD_02119 1.3e-75 S Glycosyltransferase like family 2
AICKPCKD_02120 2.5e-61 S Glycosyltransferase like family 2
AICKPCKD_02121 2.6e-117 cps1D M Domain of unknown function (DUF4422)
AICKPCKD_02122 3e-39 S CAAX protease self-immunity
AICKPCKD_02123 9.1e-89 yvyE 3.4.13.9 S YigZ family
AICKPCKD_02124 2.3e-58 S Haloacid dehalogenase-like hydrolase
AICKPCKD_02125 2.9e-153 EGP Major facilitator Superfamily
AICKPCKD_02127 5.3e-68 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
AICKPCKD_02128 1.2e-27 yraB K transcriptional regulator
AICKPCKD_02129 9.8e-90 S NADPH-dependent FMN reductase
AICKPCKD_02130 1e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
AICKPCKD_02131 1.5e-55 S ECF transporter, substrate-specific component
AICKPCKD_02132 2.5e-96 znuB U ABC 3 transport family
AICKPCKD_02133 1e-98 fhuC P ABC transporter
AICKPCKD_02134 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
AICKPCKD_02135 7.6e-38
AICKPCKD_02136 6.5e-54 XK27_01040 S Protein of unknown function (DUF1129)
AICKPCKD_02137 5.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AICKPCKD_02138 3.4e-23 yyzM S Bacterial protein of unknown function (DUF951)
AICKPCKD_02139 1.8e-108 spo0J K Belongs to the ParB family
AICKPCKD_02140 6.5e-118 soj D Sporulation initiation inhibitor
AICKPCKD_02141 1.4e-81 noc K Belongs to the ParB family
AICKPCKD_02142 4e-101 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
AICKPCKD_02143 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
AICKPCKD_02144 2.4e-109 3.1.4.46 C phosphodiesterase
AICKPCKD_02145 0.0 pacL 3.6.3.8 P P-type ATPase
AICKPCKD_02146 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
AICKPCKD_02147 1.9e-196 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
AICKPCKD_02148 6.2e-152 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
AICKPCKD_02149 2.2e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AICKPCKD_02150 1.9e-104 pfoS S Phosphotransferase system, EIIC
AICKPCKD_02151 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AICKPCKD_02152 6.6e-53 adhR K helix_turn_helix, mercury resistance
AICKPCKD_02153 5.2e-137 purR 2.4.2.7 F pur operon repressor
AICKPCKD_02154 2.1e-46 EGP Transmembrane secretion effector
AICKPCKD_02155 1.1e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AICKPCKD_02156 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AICKPCKD_02157 7.7e-19 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AICKPCKD_02158 7.6e-112 dkg S reductase
AICKPCKD_02159 1.1e-23
AICKPCKD_02160 1e-78 2.4.2.3 F Phosphorylase superfamily
AICKPCKD_02161 2e-289 ybiT S ABC transporter, ATP-binding protein
AICKPCKD_02162 1.1e-62 bCE_4747 S Beta-lactamase superfamily domain
AICKPCKD_02163 1.9e-98 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AICKPCKD_02164 1.6e-125 S overlaps another CDS with the same product name
AICKPCKD_02165 2.2e-86 S overlaps another CDS with the same product name
AICKPCKD_02167 3e-56 spoVK O ATPase family associated with various cellular activities (AAA)
AICKPCKD_02168 2.3e-22
AICKPCKD_02169 1.1e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
AICKPCKD_02171 1.3e-63
AICKPCKD_02172 2e-105 ydcZ S Putative inner membrane exporter, YdcZ
AICKPCKD_02173 7.5e-88 S hydrolase
AICKPCKD_02174 3.3e-205 ywfO S HD domain protein
AICKPCKD_02175 2e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
AICKPCKD_02176 1.8e-32 ywiB S Domain of unknown function (DUF1934)
AICKPCKD_02177 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AICKPCKD_02178 1.6e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AICKPCKD_02180 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AICKPCKD_02181 5.3e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AICKPCKD_02182 3.6e-41 rpmE2 J Ribosomal protein L31
AICKPCKD_02183 6.3e-61
AICKPCKD_02184 6.4e-257 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
AICKPCKD_02186 1.8e-78 S Cell surface protein
AICKPCKD_02188 1.2e-180 pbuG S permease
AICKPCKD_02189 2.6e-84 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AICKPCKD_02191 7.7e-61 M ErfK YbiS YcfS YnhG
AICKPCKD_02192 4.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
AICKPCKD_02193 4.1e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AICKPCKD_02194 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AICKPCKD_02195 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AICKPCKD_02196 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AICKPCKD_02197 5.4e-13
AICKPCKD_02198 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
AICKPCKD_02199 1.5e-91 yunF F Protein of unknown function DUF72
AICKPCKD_02200 6.6e-156 nrnB S DHHA1 domain
AICKPCKD_02201 1.3e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
AICKPCKD_02202 7.6e-60
AICKPCKD_02203 2.3e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
AICKPCKD_02204 7e-23 S Cytochrome B5
AICKPCKD_02205 1.1e-19 yvrI K RNA polymerase sigma factor, sigma-70 family
AICKPCKD_02206 2.9e-68 recX 2.4.1.337 GT4 S Regulatory protein RecX
AICKPCKD_02207 9.4e-192 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AICKPCKD_02208 2.6e-97 ygaC J Belongs to the UPF0374 family
AICKPCKD_02209 3.4e-91 yueF S AI-2E family transporter
AICKPCKD_02210 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
AICKPCKD_02211 1.4e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
AICKPCKD_02212 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AICKPCKD_02213 0.0 lacL 3.2.1.23 G -beta-galactosidase
AICKPCKD_02214 4e-289 lacS G Transporter
AICKPCKD_02215 5.9e-111 galR K Transcriptional regulator
AICKPCKD_02216 2.6e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AICKPCKD_02217 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AICKPCKD_02218 1.6e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
AICKPCKD_02219 0.0 rafA 3.2.1.22 G alpha-galactosidase
AICKPCKD_02220 2.9e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
AICKPCKD_02221 6.6e-23 XK27_09445 S Domain of unknown function (DUF1827)
AICKPCKD_02222 0.0 clpE O Belongs to the ClpA ClpB family
AICKPCKD_02223 1.5e-15
AICKPCKD_02224 9.7e-37 ptsH G phosphocarrier protein HPR
AICKPCKD_02225 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AICKPCKD_02226 8.8e-162 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
AICKPCKD_02227 5.4e-128 cpoA GT4 M Glycosyltransferase, group 1 family protein
AICKPCKD_02228 1.7e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AICKPCKD_02229 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
AICKPCKD_02230 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)