ORF_ID e_value Gene_name EC_number CAZy COGs Description
HMDHMNDO_00001 8.6e-115 glcR K DeoR C terminal sensor domain
HMDHMNDO_00002 4.5e-171 patA 2.6.1.1 E Aminotransferase
HMDHMNDO_00003 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMDHMNDO_00005 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMDHMNDO_00006 1.4e-172 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HMDHMNDO_00007 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
HMDHMNDO_00008 6.2e-21 S Family of unknown function (DUF5322)
HMDHMNDO_00009 5e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HMDHMNDO_00010 1.8e-38
HMDHMNDO_00013 2.5e-149 EGP Sugar (and other) transporter
HMDHMNDO_00014 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
HMDHMNDO_00015 4.8e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMDHMNDO_00016 1.9e-183 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMDHMNDO_00017 4.2e-73 alkD L DNA alkylation repair enzyme
HMDHMNDO_00018 3.8e-136 EG EamA-like transporter family
HMDHMNDO_00019 3.6e-150 S Tetratricopeptide repeat protein
HMDHMNDO_00020 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
HMDHMNDO_00021 4.3e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMDHMNDO_00022 7e-127 corA P CorA-like Mg2+ transporter protein
HMDHMNDO_00023 8.5e-161 nhaC C Na H antiporter NhaC
HMDHMNDO_00024 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMDHMNDO_00025 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HMDHMNDO_00027 7.2e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMDHMNDO_00028 2.9e-154 iscS 2.8.1.7 E Aminotransferase class V
HMDHMNDO_00029 3.7e-41 XK27_04120 S Putative amino acid metabolism
HMDHMNDO_00030 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMDHMNDO_00031 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMDHMNDO_00032 4.3e-15 S Protein of unknown function (DUF2929)
HMDHMNDO_00033 0.0 dnaE 2.7.7.7 L DNA polymerase
HMDHMNDO_00034 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMDHMNDO_00035 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HMDHMNDO_00037 1e-39 ypaA S Protein of unknown function (DUF1304)
HMDHMNDO_00038 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMDHMNDO_00039 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMDHMNDO_00040 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMDHMNDO_00041 1.2e-196 FbpA K Fibronectin-binding protein
HMDHMNDO_00042 3.1e-40 K Transcriptional regulator
HMDHMNDO_00043 2.2e-117 degV S EDD domain protein, DegV family
HMDHMNDO_00044 7.8e-71 lepB 3.4.21.89 U Signal peptidase, peptidase S26
HMDHMNDO_00045 2.4e-40 6.3.3.2 S ASCH
HMDHMNDO_00046 1.2e-185 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMDHMNDO_00047 1.7e-79 yjjH S Calcineurin-like phosphoesterase
HMDHMNDO_00048 3.1e-95 EG EamA-like transporter family
HMDHMNDO_00049 2.3e-85 natB CP ABC-type Na efflux pump, permease component
HMDHMNDO_00050 6.2e-112 natA S Domain of unknown function (DUF4162)
HMDHMNDO_00051 4.8e-23 K Acetyltransferase (GNAT) domain
HMDHMNDO_00053 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMDHMNDO_00054 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMDHMNDO_00055 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
HMDHMNDO_00056 9.1e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
HMDHMNDO_00057 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMDHMNDO_00058 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMDHMNDO_00059 1.4e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
HMDHMNDO_00060 4.5e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMDHMNDO_00061 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
HMDHMNDO_00062 4.5e-90 recO L Involved in DNA repair and RecF pathway recombination
HMDHMNDO_00063 1e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMDHMNDO_00064 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HMDHMNDO_00065 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMDHMNDO_00066 3.5e-153 phoH T phosphate starvation-inducible protein PhoH
HMDHMNDO_00067 7.5e-83 lytH 3.5.1.28 M Ami_3
HMDHMNDO_00068 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMDHMNDO_00069 5.9e-12 M Lysin motif
HMDHMNDO_00070 2e-128 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HMDHMNDO_00071 7.1e-59 ypbB 5.1.3.1 S Helix-turn-helix domain
HMDHMNDO_00072 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
HMDHMNDO_00073 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HMDHMNDO_00074 7.1e-120 ica2 GT2 M Glycosyl transferase family group 2
HMDHMNDO_00075 4.8e-44
HMDHMNDO_00076 2.8e-91 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMDHMNDO_00078 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMDHMNDO_00079 1.3e-212 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMDHMNDO_00080 4e-279 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HMDHMNDO_00081 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HMDHMNDO_00082 3.3e-117 EGP Major Facilitator Superfamily
HMDHMNDO_00083 1.1e-124 akr5f 1.1.1.346 S reductase
HMDHMNDO_00084 2.7e-72 K Transcriptional regulator
HMDHMNDO_00085 9.9e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
HMDHMNDO_00086 9.7e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDHMNDO_00087 1.3e-104 3.1.21.3 V Type I restriction modification DNA specificity domain
HMDHMNDO_00088 7e-68 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
HMDHMNDO_00089 1.6e-131 L Belongs to the 'phage' integrase family
HMDHMNDO_00090 9.3e-103 3.1.21.3 V Type I restriction modification DNA specificity domain
HMDHMNDO_00091 5.2e-202 hsdM 2.1.1.72 V type I restriction-modification system
HMDHMNDO_00092 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HMDHMNDO_00094 4.9e-22 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
HMDHMNDO_00095 2.8e-56 3.6.1.27 I Acid phosphatase homologues
HMDHMNDO_00096 2.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
HMDHMNDO_00097 4.4e-74 2.3.1.178 M GNAT acetyltransferase
HMDHMNDO_00099 1e-195 ade 3.5.4.2 F Adenine deaminase C-terminal domain
HMDHMNDO_00100 1e-64 ypsA S Belongs to the UPF0398 family
HMDHMNDO_00101 4.4e-189 nhaC C Na H antiporter NhaC
HMDHMNDO_00102 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMDHMNDO_00103 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HMDHMNDO_00104 7.3e-113 xerD D recombinase XerD
HMDHMNDO_00105 4.8e-125 cvfB S S1 domain
HMDHMNDO_00106 4.1e-51 yeaL S Protein of unknown function (DUF441)
HMDHMNDO_00107 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMDHMNDO_00108 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMDHMNDO_00109 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMDHMNDO_00110 4.5e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMDHMNDO_00111 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMDHMNDO_00112 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMDHMNDO_00113 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMDHMNDO_00114 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HMDHMNDO_00115 1.3e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HMDHMNDO_00116 1.2e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HMDHMNDO_00117 9.7e-73
HMDHMNDO_00120 4.7e-09 M LysM domain
HMDHMNDO_00121 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HMDHMNDO_00122 1e-27 ysxB J Cysteine protease Prp
HMDHMNDO_00123 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
HMDHMNDO_00126 2.2e-08 S Protein of unknown function (DUF2922)
HMDHMNDO_00128 1.3e-16 K DNA-templated transcription, initiation
HMDHMNDO_00130 1.2e-65 H Methyltransferase domain
HMDHMNDO_00131 5e-75 cps2D 5.1.3.2 M RmlD substrate binding domain
HMDHMNDO_00132 2.5e-41 wecD M Acetyltransferase (GNAT) family
HMDHMNDO_00134 1.4e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
HMDHMNDO_00135 4.4e-41 S Protein of unknown function (DUF1211)
HMDHMNDO_00137 5e-86 1.1.1.1 C Zinc-binding dehydrogenase
HMDHMNDO_00138 4.5e-30 S CHY zinc finger
HMDHMNDO_00139 2.1e-39 K Transcriptional regulator
HMDHMNDO_00140 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
HMDHMNDO_00143 5.6e-126 M Glycosyl transferases group 1
HMDHMNDO_00144 1.2e-64 M Glycosyl transferases group 1
HMDHMNDO_00145 3.7e-179 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HMDHMNDO_00146 5.5e-147 lspL 5.1.3.6 GM RmlD substrate binding domain
HMDHMNDO_00147 2.2e-104 cps2I S Psort location CytoplasmicMembrane, score
HMDHMNDO_00148 3.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
HMDHMNDO_00149 2.3e-116 S Glycosyltransferase WbsX
HMDHMNDO_00150 2.7e-52
HMDHMNDO_00152 2.5e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
HMDHMNDO_00153 1e-42 GT2 V Glycosyl transferase, family 2
HMDHMNDO_00154 1.5e-75 M Glycosyltransferase Family 4
HMDHMNDO_00155 1.8e-79 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
HMDHMNDO_00156 5.3e-121 2.4.1.52 GT4 M Glycosyl transferases group 1
HMDHMNDO_00157 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
HMDHMNDO_00158 4.8e-77 epsL M Bacterial sugar transferase
HMDHMNDO_00159 9.1e-167 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
HMDHMNDO_00160 1.2e-221 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
HMDHMNDO_00161 9.4e-65 cpsD D AAA domain
HMDHMNDO_00162 1.4e-48 cps4C M Chain length determinant protein
HMDHMNDO_00163 6.7e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HMDHMNDO_00164 2e-178 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HMDHMNDO_00165 4.8e-81
HMDHMNDO_00166 1.6e-79 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HMDHMNDO_00167 2.3e-113 yitU 3.1.3.104 S hydrolase
HMDHMNDO_00168 4.5e-60 speG J Acetyltransferase (GNAT) domain
HMDHMNDO_00169 2e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMDHMNDO_00170 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HMDHMNDO_00171 1.3e-204 pipD E Dipeptidase
HMDHMNDO_00172 2.3e-45
HMDHMNDO_00173 3.5e-64 K helix_turn_helix, arabinose operon control protein
HMDHMNDO_00174 8.9e-54 S Membrane
HMDHMNDO_00175 0.0 rafA 3.2.1.22 G alpha-galactosidase
HMDHMNDO_00176 7.6e-308 L Helicase C-terminal domain protein
HMDHMNDO_00177 1.9e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HMDHMNDO_00178 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HMDHMNDO_00179 2.4e-113 2.7.7.65 T diguanylate cyclase activity
HMDHMNDO_00180 0.0 ydaN S Bacterial cellulose synthase subunit
HMDHMNDO_00181 1.2e-201 ydaM M Glycosyl transferase family group 2
HMDHMNDO_00182 5.8e-206 S Protein conserved in bacteria
HMDHMNDO_00183 6.5e-183
HMDHMNDO_00184 1.7e-129 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
HMDHMNDO_00185 2.4e-32 2.7.7.65 T GGDEF domain
HMDHMNDO_00187 1.5e-146 pbuO_1 S Permease family
HMDHMNDO_00188 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
HMDHMNDO_00189 1.5e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HMDHMNDO_00190 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMDHMNDO_00191 3.6e-220 cydD CO ABC transporter transmembrane region
HMDHMNDO_00192 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HMDHMNDO_00193 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HMDHMNDO_00194 1.3e-193 cydA 1.10.3.14 C ubiquinol oxidase
HMDHMNDO_00195 2.6e-159 asnA 6.3.1.1 F aspartate--ammonia ligase
HMDHMNDO_00196 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
HMDHMNDO_00197 5e-19 glpE P Rhodanese Homology Domain
HMDHMNDO_00198 5.5e-49 lytE M LysM domain protein
HMDHMNDO_00199 1.4e-92 T Calcineurin-like phosphoesterase superfamily domain
HMDHMNDO_00200 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
HMDHMNDO_00202 4.4e-74 draG O ADP-ribosylglycohydrolase
HMDHMNDO_00203 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMDHMNDO_00204 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMDHMNDO_00205 8.6e-62 divIVA D DivIVA domain protein
HMDHMNDO_00206 1.7e-81 ylmH S S4 domain protein
HMDHMNDO_00207 3e-19 yggT S YGGT family
HMDHMNDO_00208 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMDHMNDO_00209 9.8e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMDHMNDO_00210 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMDHMNDO_00211 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMDHMNDO_00212 1.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMDHMNDO_00213 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMDHMNDO_00214 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMDHMNDO_00215 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
HMDHMNDO_00216 2.5e-11 ftsL D cell division protein FtsL
HMDHMNDO_00217 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMDHMNDO_00218 1.5e-55 mraZ K Belongs to the MraZ family
HMDHMNDO_00219 2.2e-07 S Protein of unknown function (DUF3397)
HMDHMNDO_00220 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HMDHMNDO_00222 9.8e-100 D Alpha beta
HMDHMNDO_00223 3.7e-109 aatB ET ABC transporter substrate-binding protein
HMDHMNDO_00224 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMDHMNDO_00225 1.9e-94 glnP P ABC transporter permease
HMDHMNDO_00226 1.8e-126 minD D Belongs to the ParA family
HMDHMNDO_00227 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HMDHMNDO_00228 2e-54 mreD M rod shape-determining protein MreD
HMDHMNDO_00229 2.1e-88 mreC M Involved in formation and maintenance of cell shape
HMDHMNDO_00230 3.6e-156 mreB D cell shape determining protein MreB
HMDHMNDO_00231 4.5e-21 K Cold shock
HMDHMNDO_00232 8.1e-80 radC L DNA repair protein
HMDHMNDO_00233 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMDHMNDO_00234 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMDHMNDO_00235 2.7e-195 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMDHMNDO_00236 6.4e-162 iscS2 2.8.1.7 E Aminotransferase class V
HMDHMNDO_00237 5.8e-175 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMDHMNDO_00238 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
HMDHMNDO_00239 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMDHMNDO_00240 3.4e-24 yueI S Protein of unknown function (DUF1694)
HMDHMNDO_00241 5.1e-184 rarA L recombination factor protein RarA
HMDHMNDO_00243 6e-72 usp6 T universal stress protein
HMDHMNDO_00244 1.1e-53 tag 3.2.2.20 L glycosylase
HMDHMNDO_00245 7.7e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMDHMNDO_00246 4.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMDHMNDO_00248 3.3e-75 yviA S Protein of unknown function (DUF421)
HMDHMNDO_00249 1.8e-27 S Protein of unknown function (DUF3290)
HMDHMNDO_00250 1.7e-277 pbp2b 3.4.16.4 M Penicillin-binding Protein
HMDHMNDO_00251 1.2e-296 S membrane
HMDHMNDO_00252 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMDHMNDO_00253 4e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
HMDHMNDO_00254 6.5e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HMDHMNDO_00255 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMDHMNDO_00257 1.4e-16
HMDHMNDO_00258 6.2e-199 oatA I Acyltransferase
HMDHMNDO_00259 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMDHMNDO_00260 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMDHMNDO_00261 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMDHMNDO_00264 5.1e-42 S Phosphoesterase
HMDHMNDO_00265 2.2e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMDHMNDO_00266 1.1e-60 yslB S Protein of unknown function (DUF2507)
HMDHMNDO_00267 9.9e-41 trxA O Belongs to the thioredoxin family
HMDHMNDO_00268 3.9e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMDHMNDO_00269 9.5e-18 cvpA S Colicin V production protein
HMDHMNDO_00270 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HMDHMNDO_00271 1.9e-33 yrzB S Belongs to the UPF0473 family
HMDHMNDO_00272 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMDHMNDO_00273 2.1e-36 yrzL S Belongs to the UPF0297 family
HMDHMNDO_00274 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMDHMNDO_00275 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMDHMNDO_00276 2.7e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HMDHMNDO_00277 7.5e-13
HMDHMNDO_00278 1e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMDHMNDO_00279 1.9e-66 yrjD S LUD domain
HMDHMNDO_00280 2.1e-245 lutB C 4Fe-4S dicluster domain
HMDHMNDO_00281 6.9e-117 lutA C Cysteine-rich domain
HMDHMNDO_00282 2e-208 yfnA E Amino Acid
HMDHMNDO_00284 3.3e-61 uspA T universal stress protein
HMDHMNDO_00286 1.8e-12 yajC U Preprotein translocase
HMDHMNDO_00287 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMDHMNDO_00288 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMDHMNDO_00289 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMDHMNDO_00290 1e-70 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMDHMNDO_00291 6e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMDHMNDO_00292 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMDHMNDO_00293 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
HMDHMNDO_00294 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMDHMNDO_00295 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMDHMNDO_00296 2.9e-64 ymfM S Helix-turn-helix domain
HMDHMNDO_00297 8.4e-91 IQ Enoyl-(Acyl carrier protein) reductase
HMDHMNDO_00298 3e-147 ymfH S Peptidase M16
HMDHMNDO_00299 3.5e-108 ymfF S Peptidase M16 inactive domain protein
HMDHMNDO_00300 1.6e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
HMDHMNDO_00301 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMDHMNDO_00302 4.1e-97 rrmA 2.1.1.187 H Methyltransferase
HMDHMNDO_00303 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
HMDHMNDO_00304 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMDHMNDO_00305 4e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMDHMNDO_00306 3.2e-21 cutC P Participates in the control of copper homeostasis
HMDHMNDO_00307 4e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HMDHMNDO_00308 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HMDHMNDO_00309 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMDHMNDO_00310 5.3e-68 ybbR S YbbR-like protein
HMDHMNDO_00311 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMDHMNDO_00312 2.4e-71 S Protein of unknown function (DUF1361)
HMDHMNDO_00313 3.5e-115 murB 1.3.1.98 M Cell wall formation
HMDHMNDO_00314 1.9e-68 dnaQ 2.7.7.7 L DNA polymerase III
HMDHMNDO_00315 3.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HMDHMNDO_00316 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HMDHMNDO_00317 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMDHMNDO_00318 2.4e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
HMDHMNDO_00319 9.1e-42 yxjI
HMDHMNDO_00320 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMDHMNDO_00321 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMDHMNDO_00322 2.8e-19 secG U Preprotein translocase
HMDHMNDO_00323 1.2e-179 clcA P chloride
HMDHMNDO_00324 6.7e-146 lmrP E Major Facilitator Superfamily
HMDHMNDO_00325 1.8e-169 T PhoQ Sensor
HMDHMNDO_00326 5e-104 K response regulator
HMDHMNDO_00327 2.2e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMDHMNDO_00328 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMDHMNDO_00329 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMDHMNDO_00330 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HMDHMNDO_00331 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMDHMNDO_00332 1.1e-136 cggR K Putative sugar-binding domain
HMDHMNDO_00334 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMDHMNDO_00335 1.8e-149 whiA K May be required for sporulation
HMDHMNDO_00336 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HMDHMNDO_00337 7.5e-126 rapZ S Displays ATPase and GTPase activities
HMDHMNDO_00338 5e-79 ylbE GM NAD dependent epimerase dehydratase family protein
HMDHMNDO_00339 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMDHMNDO_00340 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMDHMNDO_00341 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMDHMNDO_00342 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMDHMNDO_00343 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMDHMNDO_00344 8.7e-133 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMDHMNDO_00345 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HMDHMNDO_00346 2.4e-08 pspC KT PspC domain
HMDHMNDO_00347 1.2e-85 phoR 2.7.13.3 T Histidine kinase
HMDHMNDO_00348 6e-86 K response regulator
HMDHMNDO_00349 9.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HMDHMNDO_00350 2.2e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMDHMNDO_00351 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMDHMNDO_00352 9.1e-95 yeaN P Major Facilitator Superfamily
HMDHMNDO_00353 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMDHMNDO_00354 5.6e-44 comFC S Competence protein
HMDHMNDO_00355 3.2e-128 comFA L Helicase C-terminal domain protein
HMDHMNDO_00356 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
HMDHMNDO_00357 1.2e-295 ydaO E amino acid
HMDHMNDO_00358 7.4e-269 aha1 P COG COG0474 Cation transport ATPase
HMDHMNDO_00359 1.3e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMDHMNDO_00360 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMDHMNDO_00361 2.4e-33 S CAAX protease self-immunity
HMDHMNDO_00362 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMDHMNDO_00363 6.9e-257 uup S ABC transporter, ATP-binding protein
HMDHMNDO_00364 8.4e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMDHMNDO_00365 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HMDHMNDO_00366 3.7e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HMDHMNDO_00367 3.5e-140 ansA 3.5.1.1 EJ Asparaginase
HMDHMNDO_00368 4.7e-81 fat 3.1.2.21 I Acyl-ACP thioesterase
HMDHMNDO_00369 4.1e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMDHMNDO_00370 1.4e-40 yabA L Involved in initiation control of chromosome replication
HMDHMNDO_00371 3.9e-83 holB 2.7.7.7 L DNA polymerase III
HMDHMNDO_00372 1.4e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMDHMNDO_00373 9.2e-29 yaaL S Protein of unknown function (DUF2508)
HMDHMNDO_00374 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMDHMNDO_00375 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMDHMNDO_00376 4.3e-210 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMDHMNDO_00377 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMDHMNDO_00378 1.1e-75 rsmC 2.1.1.172 J Methyltransferase
HMDHMNDO_00379 1.2e-27 nrdH O Glutaredoxin
HMDHMNDO_00380 4.8e-45 nrdI F NrdI Flavodoxin like
HMDHMNDO_00381 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMDHMNDO_00382 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMDHMNDO_00383 1.6e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMDHMNDO_00384 1.4e-54
HMDHMNDO_00385 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMDHMNDO_00386 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMDHMNDO_00387 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMDHMNDO_00388 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMDHMNDO_00389 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
HMDHMNDO_00390 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMDHMNDO_00391 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMDHMNDO_00392 5.4e-71 yacP S YacP-like NYN domain
HMDHMNDO_00393 3.2e-109 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMDHMNDO_00394 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMDHMNDO_00395 1.8e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMDHMNDO_00396 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMDHMNDO_00397 4.1e-153 yacL S domain protein
HMDHMNDO_00398 5.4e-224 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMDHMNDO_00399 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HMDHMNDO_00400 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
HMDHMNDO_00401 7.6e-223 pepC 3.4.22.40 E Peptidase C1-like family
HMDHMNDO_00402 6.7e-30 S Enterocin A Immunity
HMDHMNDO_00403 4.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMDHMNDO_00404 5.9e-129 mleP2 S Sodium Bile acid symporter family
HMDHMNDO_00405 1.3e-115 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMDHMNDO_00407 7.2e-45 ydcK S Belongs to the SprT family
HMDHMNDO_00408 8.2e-251 yhgF K Tex-like protein N-terminal domain protein
HMDHMNDO_00409 3.6e-130 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMDHMNDO_00410 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMDHMNDO_00411 2.5e-90 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HMDHMNDO_00412 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
HMDHMNDO_00413 5.9e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMDHMNDO_00415 1.1e-07
HMDHMNDO_00416 7.9e-197 dtpT U amino acid peptide transporter
HMDHMNDO_00418 1.3e-63
HMDHMNDO_00419 2e-105 ydcZ S Putative inner membrane exporter, YdcZ
HMDHMNDO_00420 7.5e-88 S hydrolase
HMDHMNDO_00421 3.3e-205 ywfO S HD domain protein
HMDHMNDO_00422 2e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
HMDHMNDO_00423 1.8e-32 ywiB S Domain of unknown function (DUF1934)
HMDHMNDO_00424 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMDHMNDO_00425 1.6e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMDHMNDO_00427 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMDHMNDO_00428 5.3e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HMDHMNDO_00429 3.6e-41 rpmE2 J Ribosomal protein L31
HMDHMNDO_00430 6.3e-61
HMDHMNDO_00431 6.4e-257 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HMDHMNDO_00433 1.8e-78 S Cell surface protein
HMDHMNDO_00435 1.2e-180 pbuG S permease
HMDHMNDO_00436 2.6e-84 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMDHMNDO_00438 7.7e-61 M ErfK YbiS YcfS YnhG
HMDHMNDO_00439 4.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
HMDHMNDO_00440 4.1e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMDHMNDO_00441 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMDHMNDO_00442 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMDHMNDO_00443 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMDHMNDO_00444 5.4e-13
HMDHMNDO_00445 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
HMDHMNDO_00446 1.5e-91 yunF F Protein of unknown function DUF72
HMDHMNDO_00447 6.6e-156 nrnB S DHHA1 domain
HMDHMNDO_00448 1.3e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMDHMNDO_00449 7.6e-60
HMDHMNDO_00450 2.3e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
HMDHMNDO_00451 7e-23 S Cytochrome B5
HMDHMNDO_00452 1.1e-19 yvrI K RNA polymerase sigma factor, sigma-70 family
HMDHMNDO_00453 2.9e-68 recX 2.4.1.337 GT4 S Regulatory protein RecX
HMDHMNDO_00454 9.4e-192 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMDHMNDO_00455 2.6e-97 ygaC J Belongs to the UPF0374 family
HMDHMNDO_00456 3.4e-91 yueF S AI-2E family transporter
HMDHMNDO_00457 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HMDHMNDO_00458 1.4e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HMDHMNDO_00459 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMDHMNDO_00460 0.0 lacL 3.2.1.23 G -beta-galactosidase
HMDHMNDO_00461 4e-289 lacS G Transporter
HMDHMNDO_00462 5.9e-111 galR K Transcriptional regulator
HMDHMNDO_00463 2.6e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMDHMNDO_00464 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMDHMNDO_00465 1.6e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HMDHMNDO_00466 0.0 rafA 3.2.1.22 G alpha-galactosidase
HMDHMNDO_00467 2.9e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HMDHMNDO_00468 6.6e-23 XK27_09445 S Domain of unknown function (DUF1827)
HMDHMNDO_00469 0.0 clpE O Belongs to the ClpA ClpB family
HMDHMNDO_00470 1.5e-15
HMDHMNDO_00471 9.7e-37 ptsH G phosphocarrier protein HPR
HMDHMNDO_00472 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMDHMNDO_00473 8.8e-162 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HMDHMNDO_00474 5.4e-128 cpoA GT4 M Glycosyltransferase, group 1 family protein
HMDHMNDO_00475 1.7e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMDHMNDO_00476 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
HMDHMNDO_00477 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMDHMNDO_00478 9.8e-74 M transferase activity, transferring glycosyl groups
HMDHMNDO_00479 5.8e-57 cps3F
HMDHMNDO_00480 2e-160 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
HMDHMNDO_00481 3.7e-65 S Glycosyltransferase like family 2
HMDHMNDO_00482 1.6e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
HMDHMNDO_00483 1.8e-95 M Core-2/I-Branching enzyme
HMDHMNDO_00484 2e-91 rfbP M Bacterial sugar transferase
HMDHMNDO_00485 1.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMDHMNDO_00486 1.6e-111 ywqE 3.1.3.48 GM PHP domain protein
HMDHMNDO_00487 9.3e-82 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HMDHMNDO_00488 2.6e-77 epsB M biosynthesis protein
HMDHMNDO_00489 3.2e-214 ugd 1.1.1.22 M UDP binding domain
HMDHMNDO_00490 1e-42
HMDHMNDO_00491 3e-41 S Acyltransferase family
HMDHMNDO_00492 8e-130 S Membrane protein involved in the export of O-antigen and teichoic acid
HMDHMNDO_00493 5.8e-26 S Acetyltransferase (Isoleucine patch superfamily)
HMDHMNDO_00494 1.3e-42 M Glycosyltransferase like family 2
HMDHMNDO_00496 7.3e-46 S Glycosyl transferase family 2
HMDHMNDO_00497 4.7e-143 M Glycosyl transferase family 2
HMDHMNDO_00498 6.8e-47 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
HMDHMNDO_00499 1.9e-120 G Glycosyltransferase Family 4
HMDHMNDO_00500 9.7e-174 rgpAc GT4 M Domain of unknown function (DUF1972)
HMDHMNDO_00502 2e-80 S response to antibiotic
HMDHMNDO_00503 9.8e-27 S zinc-ribbon domain
HMDHMNDO_00504 9.4e-118 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
HMDHMNDO_00505 9.9e-128 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMDHMNDO_00506 6.2e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMDHMNDO_00507 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HMDHMNDO_00508 1.2e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMDHMNDO_00509 1.3e-75 S Glycosyltransferase like family 2
HMDHMNDO_00510 2.5e-61 S Glycosyltransferase like family 2
HMDHMNDO_00511 2.6e-117 cps1D M Domain of unknown function (DUF4422)
HMDHMNDO_00512 3e-39 S CAAX protease self-immunity
HMDHMNDO_00513 9.1e-89 yvyE 3.4.13.9 S YigZ family
HMDHMNDO_00514 2.3e-58 S Haloacid dehalogenase-like hydrolase
HMDHMNDO_00515 2.9e-153 EGP Major facilitator Superfamily
HMDHMNDO_00517 5.3e-68 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMDHMNDO_00518 1.2e-27 yraB K transcriptional regulator
HMDHMNDO_00519 9.8e-90 S NADPH-dependent FMN reductase
HMDHMNDO_00520 1e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMDHMNDO_00521 1.5e-55 S ECF transporter, substrate-specific component
HMDHMNDO_00522 2.5e-96 znuB U ABC 3 transport family
HMDHMNDO_00523 1e-98 fhuC P ABC transporter
HMDHMNDO_00524 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
HMDHMNDO_00525 7.6e-38
HMDHMNDO_00526 6.5e-54 XK27_01040 S Protein of unknown function (DUF1129)
HMDHMNDO_00527 5.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMDHMNDO_00528 3.4e-23 yyzM S Bacterial protein of unknown function (DUF951)
HMDHMNDO_00529 1.8e-108 spo0J K Belongs to the ParB family
HMDHMNDO_00530 6.5e-118 soj D Sporulation initiation inhibitor
HMDHMNDO_00531 1.4e-81 noc K Belongs to the ParB family
HMDHMNDO_00532 4e-101 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HMDHMNDO_00533 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HMDHMNDO_00534 2.4e-109 3.1.4.46 C phosphodiesterase
HMDHMNDO_00535 0.0 pacL 3.6.3.8 P P-type ATPase
HMDHMNDO_00536 4.7e-07
HMDHMNDO_00537 3.9e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HMDHMNDO_00538 1.7e-54 rplI J Binds to the 23S rRNA
HMDHMNDO_00539 1.3e-204 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMDHMNDO_00540 5.3e-64 C FMN binding
HMDHMNDO_00541 1.6e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMDHMNDO_00543 8.7e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMDHMNDO_00544 3.5e-59 ykhA 3.1.2.20 I Thioesterase superfamily
HMDHMNDO_00545 5.6e-10 S CAAX protease self-immunity
HMDHMNDO_00546 2.8e-81 S Belongs to the UPF0246 family
HMDHMNDO_00547 1.6e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HMDHMNDO_00548 9.3e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
HMDHMNDO_00549 3.7e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HMDHMNDO_00550 4.5e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HMDHMNDO_00551 3.8e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HMDHMNDO_00552 2.2e-56 3.1.3.48 K Transcriptional regulator
HMDHMNDO_00553 1.2e-197 1.3.5.4 C FMN_bind
HMDHMNDO_00554 6.5e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
HMDHMNDO_00555 2e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HMDHMNDO_00556 2.8e-139 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMDHMNDO_00557 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HMDHMNDO_00558 2e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
HMDHMNDO_00559 2.1e-106 G PTS system sorbose-specific iic component
HMDHMNDO_00560 2.4e-123 G PTS system mannose/fructose/sorbose family IID component
HMDHMNDO_00561 2e-39 2.7.1.191 G PTS system fructose IIA component
HMDHMNDO_00562 4.2e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
HMDHMNDO_00563 5.3e-112 lacI3 K helix_turn _helix lactose operon repressor
HMDHMNDO_00564 2.8e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HMDHMNDO_00565 1.5e-76 hchA S intracellular protease amidase
HMDHMNDO_00566 1.2e-21 K transcriptional regulator
HMDHMNDO_00567 5.6e-150 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HMDHMNDO_00568 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HMDHMNDO_00569 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HMDHMNDO_00570 1.5e-251 ctpA 3.6.3.54 P P-type ATPase
HMDHMNDO_00571 5e-66 pgm3 G phosphoglycerate mutase family
HMDHMNDO_00572 8.2e-55 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HMDHMNDO_00573 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMDHMNDO_00574 9.1e-219 yifK E Amino acid permease
HMDHMNDO_00575 1.4e-202 oppA E ABC transporter, substratebinding protein
HMDHMNDO_00576 1e-141 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMDHMNDO_00577 5.8e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMDHMNDO_00578 1.3e-180 oppD P Belongs to the ABC transporter superfamily
HMDHMNDO_00579 3.7e-155 oppF P Belongs to the ABC transporter superfamily
HMDHMNDO_00580 1.2e-15 psiE S Phosphate-starvation-inducible E
HMDHMNDO_00581 2.2e-209 mmuP E amino acid
HMDHMNDO_00582 7.6e-113 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HMDHMNDO_00583 4.5e-39 K LytTr DNA-binding domain
HMDHMNDO_00584 2.5e-16 S Protein of unknown function (DUF3021)
HMDHMNDO_00585 1.2e-150 yfeX P Peroxidase
HMDHMNDO_00586 1.8e-30 tetR K Transcriptional regulator C-terminal region
HMDHMNDO_00587 9.2e-47 S Short repeat of unknown function (DUF308)
HMDHMNDO_00588 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMDHMNDO_00589 6.3e-120 oxlT P Major Facilitator Superfamily
HMDHMNDO_00590 2e-67 ybbL S ABC transporter
HMDHMNDO_00591 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
HMDHMNDO_00592 4.2e-43 ytcD K HxlR-like helix-turn-helix
HMDHMNDO_00593 6.9e-121 ytbE S reductase
HMDHMNDO_00594 7.5e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMDHMNDO_00595 5.1e-42 wecD K Acetyltransferase GNAT Family
HMDHMNDO_00596 3.9e-47 hmpT S ECF-type riboflavin transporter, S component
HMDHMNDO_00597 2.1e-69 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HMDHMNDO_00598 1.7e-09 yvaZ S Protein of unknown function (DUF1648)
HMDHMNDO_00599 1.7e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
HMDHMNDO_00600 1.3e-284 pepO 3.4.24.71 O Peptidase family M13
HMDHMNDO_00601 7.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
HMDHMNDO_00602 6.9e-54 K Transcriptional regulator C-terminal region
HMDHMNDO_00603 1.6e-55 jag S R3H domain protein
HMDHMNDO_00604 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
HMDHMNDO_00605 2e-31 azlD S Branched-chain amino acid transport protein (AzlD)
HMDHMNDO_00606 2e-76 azlC E branched-chain amino acid
HMDHMNDO_00607 5.5e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HMDHMNDO_00608 9.4e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HMDHMNDO_00609 4.7e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
HMDHMNDO_00610 3.8e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HMDHMNDO_00611 1.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HMDHMNDO_00612 3.1e-75 XK27_02070 S Nitroreductase family
HMDHMNDO_00613 1.7e-111 endA F DNA RNA non-specific endonuclease
HMDHMNDO_00615 5.9e-210 brnQ U Component of the transport system for branched-chain amino acids
HMDHMNDO_00616 6.5e-61 K Bacterial regulatory proteins, tetR family
HMDHMNDO_00617 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HMDHMNDO_00618 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HMDHMNDO_00619 9.5e-69 dhaL 2.7.1.121 S Dak2
HMDHMNDO_00620 4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
HMDHMNDO_00621 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HMDHMNDO_00622 9.8e-177 yjcE P Sodium proton antiporter
HMDHMNDO_00623 4e-210 mtlR K Mga helix-turn-helix domain
HMDHMNDO_00624 5.9e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMDHMNDO_00625 6.1e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HMDHMNDO_00626 3.2e-29 ponA V the current gene model (or a revised gene model) may contain a frame shift
HMDHMNDO_00628 4.5e-102 tcyB E ABC transporter
HMDHMNDO_00629 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMDHMNDO_00630 1.3e-95 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HMDHMNDO_00631 1.6e-38 K Transcriptional regulator
HMDHMNDO_00632 2.2e-107 terC P Integral membrane protein TerC family
HMDHMNDO_00633 4.2e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HMDHMNDO_00634 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDHMNDO_00635 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HMDHMNDO_00636 1.1e-41 gntR1 K Transcriptional regulator, GntR family
HMDHMNDO_00637 8e-96 V ABC transporter, ATP-binding protein
HMDHMNDO_00638 2.5e-08
HMDHMNDO_00639 1.1e-39 ybjQ S Belongs to the UPF0145 family
HMDHMNDO_00640 4.7e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMDHMNDO_00641 1.5e-96 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMDHMNDO_00642 1e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMDHMNDO_00643 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMDHMNDO_00644 1.1e-33
HMDHMNDO_00645 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HMDHMNDO_00646 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HMDHMNDO_00647 2.3e-63 srtA 3.4.22.70 M sortase family
HMDHMNDO_00649 1.8e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HMDHMNDO_00650 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
HMDHMNDO_00651 2e-46 S CRISPR-associated protein (Cas_Csn2)
HMDHMNDO_00652 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMDHMNDO_00653 3e-106 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMDHMNDO_00654 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HMDHMNDO_00655 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HMDHMNDO_00656 2.4e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
HMDHMNDO_00657 1.6e-163 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMDHMNDO_00658 4.7e-130 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMDHMNDO_00659 2.1e-70 mltD CBM50 M NlpC P60 family protein
HMDHMNDO_00660 3.2e-52 manO S Domain of unknown function (DUF956)
HMDHMNDO_00661 2.1e-147 manN G system, mannose fructose sorbose family IID component
HMDHMNDO_00662 6.4e-116 manY G PTS system sorbose-specific iic component
HMDHMNDO_00663 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HMDHMNDO_00664 7e-80 rbsB G sugar-binding domain protein
HMDHMNDO_00665 1.6e-100 baeS T Histidine kinase
HMDHMNDO_00666 3e-79 baeR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMDHMNDO_00667 6.9e-120 G Bacterial extracellular solute-binding protein
HMDHMNDO_00668 9.1e-71 S Protein of unknown function (DUF554)
HMDHMNDO_00669 1.8e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMDHMNDO_00670 4.2e-32 merR K MerR HTH family regulatory protein
HMDHMNDO_00671 1.8e-196 lmrB EGP Major facilitator Superfamily
HMDHMNDO_00672 1.2e-33 S Domain of unknown function (DUF4811)
HMDHMNDO_00673 1.9e-41 S CAAX protease self-immunity
HMDHMNDO_00674 1e-60 yceE S haloacid dehalogenase-like hydrolase
HMDHMNDO_00675 7.6e-74 glcR K DeoR C terminal sensor domain
HMDHMNDO_00676 2.5e-95 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMDHMNDO_00677 5.7e-184 lmrB EGP Major facilitator Superfamily
HMDHMNDO_00678 1.2e-54 bioY S BioY family
HMDHMNDO_00679 2e-93 S Predicted membrane protein (DUF2207)
HMDHMNDO_00680 1.4e-19
HMDHMNDO_00681 1.4e-102 pfoS S Phosphotransferase system, EIIC
HMDHMNDO_00682 5.3e-120 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMDHMNDO_00683 1.1e-43 K helix_turn_helix isocitrate lyase regulation
HMDHMNDO_00684 4.3e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HMDHMNDO_00685 2.2e-58 ktrA P TrkA-N domain
HMDHMNDO_00686 2.1e-114 ntpJ P Potassium uptake protein
HMDHMNDO_00687 2e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HMDHMNDO_00688 6.1e-282 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
HMDHMNDO_00689 1.8e-217 scrB 3.2.1.26 GH32 G invertase
HMDHMNDO_00690 1.7e-147 scrR K helix_turn _helix lactose operon repressor
HMDHMNDO_00691 8.8e-50 yugI 5.3.1.9 J general stress protein
HMDHMNDO_00692 2.7e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HMDHMNDO_00693 3e-92 dedA S SNARE associated Golgi protein
HMDHMNDO_00694 7.8e-32 S Protein of unknown function (DUF1461)
HMDHMNDO_00695 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMDHMNDO_00696 1.9e-53 yutD S Protein of unknown function (DUF1027)
HMDHMNDO_00697 3e-57 S Calcineurin-like phosphoesterase
HMDHMNDO_00698 9.3e-184 cycA E Amino acid permease
HMDHMNDO_00699 7.6e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
HMDHMNDO_00701 5.5e-11 S Putative Competence protein ComGF
HMDHMNDO_00703 1.5e-13
HMDHMNDO_00704 1.2e-27 comGC U competence protein ComGC
HMDHMNDO_00705 5.7e-98 comGB NU type II secretion system
HMDHMNDO_00706 4.7e-121 comGA NU Type II IV secretion system protein
HMDHMNDO_00707 2.1e-102 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMDHMNDO_00708 1.5e-119 yebC K Transcriptional regulatory protein
HMDHMNDO_00709 1.5e-29 S VanZ like family
HMDHMNDO_00710 1.3e-158 ccpA K catabolite control protein A
HMDHMNDO_00711 1e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMDHMNDO_00712 1.5e-13
HMDHMNDO_00715 5.9e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMDHMNDO_00716 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
HMDHMNDO_00717 5.2e-65 hly S protein, hemolysin III
HMDHMNDO_00718 7.3e-41 M1-874 K Domain of unknown function (DUF1836)
HMDHMNDO_00719 9.4e-84 S membrane
HMDHMNDO_00720 1.1e-79 S VIT family
HMDHMNDO_00721 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HMDHMNDO_00722 7.9e-56 P Plays a role in the regulation of phosphate uptake
HMDHMNDO_00723 1.8e-115 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMDHMNDO_00724 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMDHMNDO_00725 3e-122 pstA P Phosphate transport system permease protein PstA
HMDHMNDO_00726 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
HMDHMNDO_00727 3.2e-97 pstS P Phosphate
HMDHMNDO_00728 1.3e-41 yjbH Q Thioredoxin
HMDHMNDO_00729 3.3e-232 pepF E oligoendopeptidase F
HMDHMNDO_00730 1.1e-68 coiA 3.6.4.12 S Competence protein
HMDHMNDO_00731 2.1e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMDHMNDO_00732 1.4e-218 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HMDHMNDO_00734 1.1e-135 tetA EGP Major facilitator Superfamily
HMDHMNDO_00735 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
HMDHMNDO_00736 2.5e-214 yjeM E Amino Acid
HMDHMNDO_00737 1.9e-190 glnPH2 P ABC transporter permease
HMDHMNDO_00738 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMDHMNDO_00739 2.8e-44 E GDSL-like Lipase/Acylhydrolase
HMDHMNDO_00740 1e-133 coaA 2.7.1.33 F Pantothenic acid kinase
HMDHMNDO_00741 7.6e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HMDHMNDO_00742 3.3e-82
HMDHMNDO_00743 8.5e-34 S Predicted membrane protein (DUF2142)
HMDHMNDO_00744 5e-115 rfbJ M Glycosyl transferase family 2
HMDHMNDO_00745 2.1e-30 gtcA S Teichoic acid glycosylation protein
HMDHMNDO_00746 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMDHMNDO_00747 1.2e-160 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMDHMNDO_00748 4.7e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMDHMNDO_00749 5.4e-67 XK27_09620 S NADPH-dependent FMN reductase
HMDHMNDO_00750 2.7e-156 XK27_09615 S reductase
HMDHMNDO_00751 1.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
HMDHMNDO_00752 3.3e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HMDHMNDO_00753 1.5e-55 S Psort location CytoplasmicMembrane, score
HMDHMNDO_00754 3.6e-14
HMDHMNDO_00755 2.5e-72 S Bacterial membrane protein, YfhO
HMDHMNDO_00756 8.8e-102 S Bacterial membrane protein, YfhO
HMDHMNDO_00757 3.2e-129 S Bacterial membrane protein YfhO
HMDHMNDO_00758 1e-94 XK27_08315 M Sulfatase
HMDHMNDO_00759 7.5e-99 M Collagen binding domain
HMDHMNDO_00760 5.4e-69 pnuC H Nicotinamide mononucleotide transporter
HMDHMNDO_00762 2.1e-34 V HNH endonuclease
HMDHMNDO_00763 6.5e-254 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HMDHMNDO_00764 2.1e-197 L Psort location Cytoplasmic, score
HMDHMNDO_00765 2.2e-18
HMDHMNDO_00766 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMDHMNDO_00767 8.4e-64
HMDHMNDO_00768 7.1e-150
HMDHMNDO_00769 5.2e-63
HMDHMNDO_00770 2.5e-257 traK U TraM recognition site of TraD and TraG
HMDHMNDO_00771 3e-81
HMDHMNDO_00772 6.3e-87
HMDHMNDO_00773 1.9e-186 M CHAP domain
HMDHMNDO_00774 2.1e-207 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
HMDHMNDO_00775 0.0 traE U AAA-like domain
HMDHMNDO_00776 8.4e-114
HMDHMNDO_00777 8.6e-36
HMDHMNDO_00778 1e-51 S Cag pathogenicity island, type IV secretory system
HMDHMNDO_00779 1.5e-104
HMDHMNDO_00780 2.1e-51
HMDHMNDO_00781 1.8e-204 L MobA MobL family protein
HMDHMNDO_00782 8.2e-185 L MobA MobL family protein
HMDHMNDO_00783 2.5e-27
HMDHMNDO_00784 5.4e-17
HMDHMNDO_00785 1.4e-41
HMDHMNDO_00786 4.1e-116 S protein conserved in bacteria
HMDHMNDO_00787 1.1e-26
HMDHMNDO_00788 1.6e-42 relB L Addiction module antitoxin, RelB DinJ family
HMDHMNDO_00789 1.1e-73 repA S Replication initiator protein A
HMDHMNDO_00790 1.9e-50 repA S Replication initiator protein A
HMDHMNDO_00791 1.3e-65 repA S Replication initiator protein A (RepA) N-terminus
HMDHMNDO_00793 1.5e-146 D CobQ CobB MinD ParA nucleotide binding domain protein
HMDHMNDO_00794 3.5e-82 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMDHMNDO_00795 4.1e-177 thrC 4.2.3.1 E Threonine synthase
HMDHMNDO_00796 2.4e-128 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMDHMNDO_00797 5.2e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HMDHMNDO_00798 5.6e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMDHMNDO_00799 5.1e-57 S peptidoglycan catabolic process
HMDHMNDO_00800 1.5e-194 XK27_08315 M Sulfatase
HMDHMNDO_00802 6.4e-168 mdtG EGP Major facilitator Superfamily
HMDHMNDO_00803 6.3e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HMDHMNDO_00804 5.7e-84 treR K UTRA
HMDHMNDO_00805 3.3e-259 treB G phosphotransferase system
HMDHMNDO_00806 3.5e-63 3.1.3.73 G phosphoglycerate mutase
HMDHMNDO_00807 2.4e-82 pncA Q isochorismatase
HMDHMNDO_00808 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HMDHMNDO_00809 1.2e-103 ydhQ K UbiC transcription regulator-associated domain protein
HMDHMNDO_00810 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMDHMNDO_00811 3.6e-41 K Transcriptional regulator, HxlR family
HMDHMNDO_00812 8.3e-164 C Luciferase-like monooxygenase
HMDHMNDO_00813 6.4e-12
HMDHMNDO_00814 1.5e-143 iunH2 3.2.2.1 F nucleoside hydrolase
HMDHMNDO_00815 7.6e-43 XK27_03960 S Protein of unknown function (DUF3013)
HMDHMNDO_00816 5.8e-118 prmA J Ribosomal protein L11 methyltransferase
HMDHMNDO_00817 3.1e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMDHMNDO_00818 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMDHMNDO_00819 1.7e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMDHMNDO_00820 6.7e-57 3.1.3.18 J HAD-hyrolase-like
HMDHMNDO_00821 1.3e-41 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMDHMNDO_00822 7.3e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMDHMNDO_00823 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMDHMNDO_00824 2.7e-204 pyrP F Permease
HMDHMNDO_00825 4.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMDHMNDO_00826 5.9e-192 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HMDHMNDO_00827 1.5e-84 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMDHMNDO_00828 2.3e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMDHMNDO_00829 9.8e-135 K Transcriptional regulator
HMDHMNDO_00830 6.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
HMDHMNDO_00833 2.1e-07
HMDHMNDO_00850 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMDHMNDO_00851 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMDHMNDO_00852 9.7e-194 cycA E Amino acid permease
HMDHMNDO_00853 8.3e-187 ytgP S Polysaccharide biosynthesis protein
HMDHMNDO_00854 1.1e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMDHMNDO_00855 1.2e-80 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMDHMNDO_00856 5.1e-193 pepV 3.5.1.18 E dipeptidase PepV
HMDHMNDO_00857 3.3e-182 S Protein of unknown function DUF262
HMDHMNDO_00859 3e-36
HMDHMNDO_00860 1.3e-65 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMDHMNDO_00861 4.2e-61 marR K Transcriptional regulator, MarR family
HMDHMNDO_00862 6.4e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMDHMNDO_00863 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMDHMNDO_00864 6.5e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HMDHMNDO_00865 1.4e-98 IQ reductase
HMDHMNDO_00866 1.8e-194 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMDHMNDO_00867 7.9e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMDHMNDO_00868 1.5e-63 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMDHMNDO_00869 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HMDHMNDO_00870 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMDHMNDO_00871 2.3e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HMDHMNDO_00872 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HMDHMNDO_00873 1.5e-230 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMDHMNDO_00874 9.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
HMDHMNDO_00875 2.7e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMDHMNDO_00876 5.7e-119 gla U Major intrinsic protein
HMDHMNDO_00877 1.5e-45 ykuL S CBS domain
HMDHMNDO_00878 1.5e-60 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMDHMNDO_00879 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMDHMNDO_00880 2.1e-88 ykuT M mechanosensitive ion channel
HMDHMNDO_00882 1e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMDHMNDO_00883 2e-21 yheA S Belongs to the UPF0342 family
HMDHMNDO_00884 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMDHMNDO_00885 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMDHMNDO_00887 5.4e-53 hit FG histidine triad
HMDHMNDO_00888 1.4e-93 ecsA V ABC transporter, ATP-binding protein
HMDHMNDO_00889 1.3e-72 ecsB U ABC transporter
HMDHMNDO_00890 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HMDHMNDO_00891 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMDHMNDO_00892 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMDHMNDO_00893 6.8e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMDHMNDO_00894 9e-240 sftA D Belongs to the FtsK SpoIIIE SftA family
HMDHMNDO_00895 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HMDHMNDO_00896 9.4e-61 phaJ I N-terminal half of MaoC dehydratase
HMDHMNDO_00897 6.7e-69 ybhL S Belongs to the BI1 family
HMDHMNDO_00898 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMDHMNDO_00899 9.5e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMDHMNDO_00900 2.1e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMDHMNDO_00901 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMDHMNDO_00902 1.6e-79 dnaB L replication initiation and membrane attachment
HMDHMNDO_00903 2.2e-107 dnaI L Primosomal protein DnaI
HMDHMNDO_00904 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMDHMNDO_00905 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMDHMNDO_00906 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HMDHMNDO_00907 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMDHMNDO_00908 2.5e-71 yqeG S HAD phosphatase, family IIIA
HMDHMNDO_00909 7.9e-181 yqeH S Ribosome biogenesis GTPase YqeH
HMDHMNDO_00910 1e-29 yhbY J RNA-binding protein
HMDHMNDO_00911 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMDHMNDO_00912 7.2e-72 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HMDHMNDO_00913 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMDHMNDO_00914 4.2e-82 H Nodulation protein S (NodS)
HMDHMNDO_00915 1.3e-122 ylbM S Belongs to the UPF0348 family
HMDHMNDO_00916 2e-57 yceD S Uncharacterized ACR, COG1399
HMDHMNDO_00917 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HMDHMNDO_00918 1.2e-88 plsC 2.3.1.51 I Acyltransferase
HMDHMNDO_00919 1.1e-93 yabB 2.1.1.223 L Methyltransferase small domain
HMDHMNDO_00920 1.5e-27 yazA L GIY-YIG catalytic domain protein
HMDHMNDO_00921 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
HMDHMNDO_00922 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMDHMNDO_00923 6.9e-37
HMDHMNDO_00924 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HMDHMNDO_00925 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMDHMNDO_00926 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMDHMNDO_00927 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMDHMNDO_00928 8.6e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMDHMNDO_00930 3.1e-111 K response regulator
HMDHMNDO_00931 5e-167 arlS 2.7.13.3 T Histidine kinase
HMDHMNDO_00932 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMDHMNDO_00933 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HMDHMNDO_00934 5.6e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HMDHMNDO_00935 7.3e-105
HMDHMNDO_00936 7.2e-117
HMDHMNDO_00937 1.3e-41 dut S dUTPase
HMDHMNDO_00938 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMDHMNDO_00939 3.7e-46 yqhY S Asp23 family, cell envelope-related function
HMDHMNDO_00940 1.9e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMDHMNDO_00941 1.7e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMDHMNDO_00942 1.2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMDHMNDO_00943 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMDHMNDO_00944 4.7e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMDHMNDO_00945 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HMDHMNDO_00946 6.6e-49 argR K Regulates arginine biosynthesis genes
HMDHMNDO_00947 4.2e-178 recN L May be involved in recombinational repair of damaged DNA
HMDHMNDO_00948 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMDHMNDO_00949 2.2e-30 ynzC S UPF0291 protein
HMDHMNDO_00950 5.9e-27 yneF S UPF0154 protein
HMDHMNDO_00951 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
HMDHMNDO_00952 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HMDHMNDO_00953 1.2e-74 yciQ P membrane protein (DUF2207)
HMDHMNDO_00954 3e-19 D nuclear chromosome segregation
HMDHMNDO_00955 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMDHMNDO_00956 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMDHMNDO_00957 7.4e-70 gluP 3.4.21.105 S Peptidase, S54 family
HMDHMNDO_00958 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
HMDHMNDO_00959 4.7e-158 glk 2.7.1.2 G Glucokinase
HMDHMNDO_00960 2.7e-46 yqhL P Rhodanese-like protein
HMDHMNDO_00961 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
HMDHMNDO_00962 1.9e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMDHMNDO_00963 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
HMDHMNDO_00964 1.3e-45 glnR K Transcriptional regulator
HMDHMNDO_00965 2e-247 glnA 6.3.1.2 E glutamine synthetase
HMDHMNDO_00967 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HMDHMNDO_00968 2.7e-48 S Domain of unknown function (DUF956)
HMDHMNDO_00969 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HMDHMNDO_00970 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMDHMNDO_00971 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMDHMNDO_00972 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
HMDHMNDO_00973 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HMDHMNDO_00974 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMDHMNDO_00975 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMDHMNDO_00976 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
HMDHMNDO_00977 1.8e-169 nusA K Participates in both transcription termination and antitermination
HMDHMNDO_00978 1.4e-39 ylxR K Protein of unknown function (DUF448)
HMDHMNDO_00979 6.9e-26 ylxQ J ribosomal protein
HMDHMNDO_00980 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMDHMNDO_00981 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMDHMNDO_00982 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMDHMNDO_00983 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HMDHMNDO_00984 1.1e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMDHMNDO_00985 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMDHMNDO_00986 1.5e-274 dnaK O Heat shock 70 kDa protein
HMDHMNDO_00987 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMDHMNDO_00988 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMDHMNDO_00990 9.2e-206 glnP P ABC transporter
HMDHMNDO_00991 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMDHMNDO_00992 1.5e-31
HMDHMNDO_00993 2e-111 ampC V Beta-lactamase
HMDHMNDO_00994 3.5e-110 cobQ S glutamine amidotransferase
HMDHMNDO_00995 3.6e-220 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HMDHMNDO_00996 6.8e-86 tdk 2.7.1.21 F thymidine kinase
HMDHMNDO_00997 2.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMDHMNDO_00998 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMDHMNDO_00999 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMDHMNDO_01000 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMDHMNDO_01001 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
HMDHMNDO_01002 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMDHMNDO_01003 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMDHMNDO_01004 2.7e-57 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMDHMNDO_01005 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMDHMNDO_01006 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMDHMNDO_01007 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMDHMNDO_01008 3.9e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HMDHMNDO_01009 4.1e-15 ywzB S Protein of unknown function (DUF1146)
HMDHMNDO_01010 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMDHMNDO_01011 3.4e-167 mbl D Cell shape determining protein MreB Mrl
HMDHMNDO_01012 1.2e-26 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HMDHMNDO_01013 1.8e-12 S Protein of unknown function (DUF2969)
HMDHMNDO_01014 6.1e-187 rodA D Belongs to the SEDS family
HMDHMNDO_01015 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
HMDHMNDO_01016 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
HMDHMNDO_01017 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HMDHMNDO_01018 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMDHMNDO_01019 4.4e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMDHMNDO_01020 2.4e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMDHMNDO_01021 5.8e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMDHMNDO_01022 1.7e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMDHMNDO_01023 3.3e-90 stp 3.1.3.16 T phosphatase
HMDHMNDO_01024 3.4e-191 KLT serine threonine protein kinase
HMDHMNDO_01025 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMDHMNDO_01026 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
HMDHMNDO_01027 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HMDHMNDO_01028 4.5e-53 asp S Asp23 family, cell envelope-related function
HMDHMNDO_01029 2.8e-238 yloV S DAK2 domain fusion protein YloV
HMDHMNDO_01030 3.3e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMDHMNDO_01031 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMDHMNDO_01032 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMDHMNDO_01033 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMDHMNDO_01034 4.7e-211 smc D Required for chromosome condensation and partitioning
HMDHMNDO_01035 1.7e-147 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMDHMNDO_01036 7e-40 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMDHMNDO_01037 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMDHMNDO_01038 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HMDHMNDO_01039 1.1e-26 ylqC S Belongs to the UPF0109 family
HMDHMNDO_01040 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMDHMNDO_01041 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HMDHMNDO_01042 5.7e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
HMDHMNDO_01043 7e-198 yfnA E amino acid
HMDHMNDO_01044 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMDHMNDO_01045 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
HMDHMNDO_01046 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMDHMNDO_01047 5.3e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMDHMNDO_01048 4.9e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMDHMNDO_01049 5.6e-20 S Tetratricopeptide repeat
HMDHMNDO_01050 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMDHMNDO_01051 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMDHMNDO_01052 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMDHMNDO_01053 2.3e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMDHMNDO_01054 1.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMDHMNDO_01055 5e-23 ykzG S Belongs to the UPF0356 family
HMDHMNDO_01056 1.6e-24
HMDHMNDO_01057 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMDHMNDO_01058 3.7e-32 1.1.1.27 C L-malate dehydrogenase activity
HMDHMNDO_01059 1.7e-23 yktA S Belongs to the UPF0223 family
HMDHMNDO_01060 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HMDHMNDO_01061 0.0 typA T GTP-binding protein TypA
HMDHMNDO_01062 6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HMDHMNDO_01063 7e-115 manY G PTS system
HMDHMNDO_01064 3.3e-148 manN G system, mannose fructose sorbose family IID component
HMDHMNDO_01065 1.6e-102 ftsW D Belongs to the SEDS family
HMDHMNDO_01066 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HMDHMNDO_01067 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HMDHMNDO_01068 7.2e-74 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HMDHMNDO_01069 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMDHMNDO_01070 2.4e-131 ylbL T Belongs to the peptidase S16 family
HMDHMNDO_01071 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HMDHMNDO_01072 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMDHMNDO_01073 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMDHMNDO_01074 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMDHMNDO_01075 3.6e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMDHMNDO_01076 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HMDHMNDO_01077 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMDHMNDO_01078 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HMDHMNDO_01079 3e-152 purD 6.3.4.13 F Belongs to the GARS family
HMDHMNDO_01080 1.5e-93 S Acyltransferase family
HMDHMNDO_01081 2.2e-194 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMDHMNDO_01082 3.9e-122 K LysR substrate binding domain
HMDHMNDO_01084 2.2e-20
HMDHMNDO_01085 6.2e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMDHMNDO_01086 5.8e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
HMDHMNDO_01087 1.4e-50 comEA L Competence protein ComEA
HMDHMNDO_01088 2e-69 comEB 3.5.4.12 F ComE operon protein 2
HMDHMNDO_01089 1.4e-155 comEC S Competence protein ComEC
HMDHMNDO_01090 9.3e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
HMDHMNDO_01091 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMDHMNDO_01092 3e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HMDHMNDO_01093 2.8e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HMDHMNDO_01094 8.1e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HMDHMNDO_01095 7.4e-228 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMDHMNDO_01096 1.8e-36 ypmB S Protein conserved in bacteria
HMDHMNDO_01097 4e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HMDHMNDO_01098 1e-235 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HMDHMNDO_01099 5.1e-56 dnaD L DnaD domain protein
HMDHMNDO_01100 9.7e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMDHMNDO_01101 9.9e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMDHMNDO_01102 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMDHMNDO_01103 1.9e-93 M transferase activity, transferring glycosyl groups
HMDHMNDO_01104 1.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
HMDHMNDO_01105 1.3e-99 epsJ1 M Glycosyltransferase like family 2
HMDHMNDO_01108 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HMDHMNDO_01109 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HMDHMNDO_01110 1.8e-56 yqeY S YqeY-like protein
HMDHMNDO_01112 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
HMDHMNDO_01113 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMDHMNDO_01114 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMDHMNDO_01115 6.6e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMDHMNDO_01116 2.9e-276 yfmR S ABC transporter, ATP-binding protein
HMDHMNDO_01117 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMDHMNDO_01118 9.4e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMDHMNDO_01119 8.6e-135 yvgN C Aldo keto reductase
HMDHMNDO_01120 2.4e-35 K helix_turn_helix, mercury resistance
HMDHMNDO_01121 1.3e-102 S Aldo keto reductase
HMDHMNDO_01123 1.4e-77 ypmR E GDSL-like Lipase/Acylhydrolase
HMDHMNDO_01124 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HMDHMNDO_01125 3.6e-24 yozE S Belongs to the UPF0346 family
HMDHMNDO_01126 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMDHMNDO_01127 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMDHMNDO_01128 6.2e-85 dprA LU DNA protecting protein DprA
HMDHMNDO_01129 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMDHMNDO_01130 1e-208 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMDHMNDO_01131 5.8e-205 G PTS system Galactitol-specific IIC component
HMDHMNDO_01132 2.3e-81 K Bacterial regulatory proteins, tetR family
HMDHMNDO_01133 3.3e-129 yjjC V ATPases associated with a variety of cellular activities
HMDHMNDO_01134 1.1e-202 M Exporter of polyketide antibiotics
HMDHMNDO_01135 4e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HMDHMNDO_01136 2.3e-34 S Repeat protein
HMDHMNDO_01137 5.8e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMDHMNDO_01139 1.7e-15
HMDHMNDO_01142 5.9e-87 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMDHMNDO_01143 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMDHMNDO_01144 9.1e-43 yodB K Transcriptional regulator, HxlR family
HMDHMNDO_01145 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMDHMNDO_01146 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMDHMNDO_01147 9.3e-129 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMDHMNDO_01148 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
HMDHMNDO_01149 2.2e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMDHMNDO_01150 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HMDHMNDO_01151 2.5e-211 glnP P ABC transporter
HMDHMNDO_01153 6.6e-60 uspA T Universal stress protein family
HMDHMNDO_01154 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
HMDHMNDO_01155 1.1e-25
HMDHMNDO_01156 2.9e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HMDHMNDO_01157 8e-110 puuD S peptidase C26
HMDHMNDO_01158 5.2e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMDHMNDO_01159 4.3e-150 lsa S ABC transporter
HMDHMNDO_01160 7.2e-149 mepA V MATE efflux family protein
HMDHMNDO_01161 8.7e-67 1.5.1.38 S NADPH-dependent FMN reductase
HMDHMNDO_01162 5.8e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HMDHMNDO_01163 3.9e-76 L haloacid dehalogenase-like hydrolase
HMDHMNDO_01164 4e-61 EG EamA-like transporter family
HMDHMNDO_01165 5.3e-118 K AI-2E family transporter
HMDHMNDO_01166 1.3e-173 malY 4.4.1.8 E Aminotransferase, class I
HMDHMNDO_01167 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMDHMNDO_01169 5.3e-35 S virion core protein, lumpy skin disease virus
HMDHMNDO_01170 5.8e-149 cbiO2 P ABC transporter
HMDHMNDO_01171 7.8e-157 P ABC transporter
HMDHMNDO_01172 9.7e-133 cbiQ P Cobalt transport protein
HMDHMNDO_01173 7e-91 2.7.7.65 T phosphorelay sensor kinase activity
HMDHMNDO_01174 3e-62 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HMDHMNDO_01175 4.7e-22
HMDHMNDO_01179 4.3e-133 D CobQ CobB MinD ParA nucleotide binding domain protein
HMDHMNDO_01180 6.2e-29 relB L RelB antitoxin
HMDHMNDO_01181 1.4e-39 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HMDHMNDO_01182 1.5e-55 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HMDHMNDO_01183 1.2e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HMDHMNDO_01185 3.1e-96 K Transcriptional regulator
HMDHMNDO_01186 4.3e-59 arsR K DNA-binding transcription factor activity
HMDHMNDO_01187 2.4e-270 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMDHMNDO_01188 3.6e-131 3.6.1.13, 3.6.1.55 F NUDIX domain
HMDHMNDO_01189 8.8e-164 L An automated process has identified a potential problem with this gene model
HMDHMNDO_01190 2.7e-46 rimL J Acetyltransferase (GNAT) domain
HMDHMNDO_01191 1.7e-79 S AAA domain
HMDHMNDO_01192 4.4e-69 5.4.2.11 G Phosphoglycerate mutase family
HMDHMNDO_01193 1.2e-253 XK27_06780 V ABC transporter permease
HMDHMNDO_01194 6.4e-96 XK27_06785 V ABC transporter, ATP-binding protein
HMDHMNDO_01195 9.2e-70 rny D Peptidase family M23
HMDHMNDO_01197 6.7e-114 L Transposase IS66 family
HMDHMNDO_01198 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
HMDHMNDO_01200 4.5e-198 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HMDHMNDO_01201 1.9e-39
HMDHMNDO_01203 8.2e-16
HMDHMNDO_01204 2.1e-112 rssA S Phospholipase, patatin family
HMDHMNDO_01205 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMDHMNDO_01206 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HMDHMNDO_01207 3.3e-45 S VIT family
HMDHMNDO_01208 9.4e-240 sufB O assembly protein SufB
HMDHMNDO_01209 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
HMDHMNDO_01210 3.3e-148 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMDHMNDO_01211 5.6e-143 sufD O FeS assembly protein SufD
HMDHMNDO_01212 1.8e-115 sufC O FeS assembly ATPase SufC
HMDHMNDO_01213 3.2e-223 E ABC transporter, substratebinding protein
HMDHMNDO_01215 7.7e-20 S protein encoded in hypervariable junctions of pilus gene clusters
HMDHMNDO_01216 2.5e-27 K Helix-turn-helix XRE-family like proteins
HMDHMNDO_01218 9.6e-47 V ABC-2 family transporter protein
HMDHMNDO_01219 3.3e-73 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
HMDHMNDO_01220 1.7e-105 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HMDHMNDO_01221 8.8e-90 KT Transcriptional regulatory protein, C terminal
HMDHMNDO_01222 1.4e-58 spaC2 V Lanthionine synthetase C-like protein
HMDHMNDO_01223 4.3e-184 spaT V ATPases associated with a variety of cellular activities
HMDHMNDO_01224 2.6e-207 spaB S Lantibiotic dehydratase, C terminus
HMDHMNDO_01226 2.5e-136 pfoS S Phosphotransferase system, EIIC
HMDHMNDO_01227 5.5e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HMDHMNDO_01228 9.1e-63 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
HMDHMNDO_01229 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HMDHMNDO_01230 1.4e-136 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HMDHMNDO_01231 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
HMDHMNDO_01232 4.5e-43 gutM K Glucitol operon activator protein (GutM)
HMDHMNDO_01233 5.8e-104 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HMDHMNDO_01234 4e-110 IQ NAD dependent epimerase/dehydratase family
HMDHMNDO_01235 4.7e-163 ytbD EGP Major facilitator Superfamily
HMDHMNDO_01236 3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
HMDHMNDO_01237 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMDHMNDO_01238 1.2e-189 tonB M YSIRK type signal peptide
HMDHMNDO_01239 2.2e-263 fbp 3.1.3.11 G phosphatase activity
HMDHMNDO_01240 1.9e-70 xerD L Phage integrase, N-terminal SAM-like domain
HMDHMNDO_01243 2e-86 mesE M Transport protein ComB
HMDHMNDO_01244 4e-282 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMDHMNDO_01252 1.9e-56 K LytTr DNA-binding domain
HMDHMNDO_01253 8.8e-59 2.7.13.3 T GHKL domain
HMDHMNDO_01258 1.1e-16
HMDHMNDO_01259 1.2e-12
HMDHMNDO_01261 4.2e-08
HMDHMNDO_01262 4.2e-37 blpT
HMDHMNDO_01263 1.8e-14
HMDHMNDO_01265 7.8e-187 mtnE 2.6.1.83 E Aminotransferase
HMDHMNDO_01266 6.5e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HMDHMNDO_01267 1.3e-66 S Protein of unknown function (DUF1440)
HMDHMNDO_01268 7.7e-41 S Iron-sulfur cluster assembly protein
HMDHMNDO_01269 5.5e-113 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HMDHMNDO_01270 1.5e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HMDHMNDO_01271 6.6e-207 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMDHMNDO_01272 3.9e-154 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMDHMNDO_01273 2.3e-64 G Xylose isomerase domain protein TIM barrel
HMDHMNDO_01274 3.8e-54 ndk 2.7.4.6 F Belongs to the NDK family
HMDHMNDO_01275 1.2e-88 nanK GK ROK family
HMDHMNDO_01276 3.3e-126 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HMDHMNDO_01277 1.6e-91 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HMDHMNDO_01278 7.8e-77 K Helix-turn-helix domain, rpiR family
HMDHMNDO_01279 3.5e-61 yphA GM NAD dependent epimerase/dehydratase family
HMDHMNDO_01280 3.1e-217 yjeM E Amino Acid
HMDHMNDO_01282 1.2e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMDHMNDO_01283 1e-231 tetP J elongation factor G
HMDHMNDO_01284 1.1e-278 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMDHMNDO_01285 1.3e-87 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HMDHMNDO_01286 1.1e-166 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HMDHMNDO_01287 2.8e-119 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HMDHMNDO_01288 2.4e-181 gatC G PTS system sugar-specific permease component
HMDHMNDO_01289 2e-35 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HMDHMNDO_01290 2.7e-39 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMDHMNDO_01291 2.2e-60 K DeoR C terminal sensor domain
HMDHMNDO_01292 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HMDHMNDO_01293 9.4e-41 S Fic/DOC family
HMDHMNDO_01294 3.1e-11 S Fic/DOC family
HMDHMNDO_01295 8.3e-47 S Fic/DOC family
HMDHMNDO_01296 1.9e-09 yokH G regulation of fungal-type cell wall biogenesis
HMDHMNDO_01297 9.4e-109 L Initiator Replication protein
HMDHMNDO_01298 3.9e-38 S Replication initiator protein A (RepA) N-terminus
HMDHMNDO_01299 5.9e-173 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMDHMNDO_01300 6e-205 G Pts system
HMDHMNDO_01301 2.1e-64 licT K transcriptional antiterminator
HMDHMNDO_01302 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
HMDHMNDO_01304 1.8e-33
HMDHMNDO_01305 6.9e-08 S CAAX protease self-immunity
HMDHMNDO_01306 0.0 pepN 3.4.11.2 E aminopeptidase
HMDHMNDO_01307 2.1e-44 2.7.13.3 T protein histidine kinase activity
HMDHMNDO_01308 1.3e-35 agrA KT Response regulator of the LytR AlgR family
HMDHMNDO_01309 9.8e-21 M domain protein
HMDHMNDO_01313 3.6e-09
HMDHMNDO_01314 3.4e-16
HMDHMNDO_01318 1.8e-124 yvgN C Aldo keto reductase
HMDHMNDO_01319 3.9e-105 yraQ S Predicted permease
HMDHMNDO_01320 1.1e-62 yeeE S Sulphur transport
HMDHMNDO_01321 1.6e-16 yeeD O Belongs to the sulfur carrier protein TusA family
HMDHMNDO_01322 2.2e-116 ynjE 2.8.1.11 P Rhodanese Homology Domain
HMDHMNDO_01324 4.3e-235 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
HMDHMNDO_01325 7.1e-26 S Psort location Cytoplasmic, score
HMDHMNDO_01326 7.6e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
HMDHMNDO_01327 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
HMDHMNDO_01328 1.6e-73 prdD S An automated process has identified a potential problem with this gene model
HMDHMNDO_01329 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
HMDHMNDO_01330 7e-144 5.1.1.4 E Proline racemase
HMDHMNDO_01331 4.4e-94 XK27_00825 S Sulfite exporter TauE/SafE
HMDHMNDO_01332 4.5e-222 ybeC E amino acid
HMDHMNDO_01333 1.2e-48 yedF O Belongs to the sulfur carrier protein TusA family
HMDHMNDO_01334 4.5e-08 S Protein of unknown function (DUF3343)
HMDHMNDO_01335 4.8e-138 selB J Elongation factor SelB, winged helix
HMDHMNDO_01336 5.1e-111 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
HMDHMNDO_01337 2e-109 selA 2.9.1.1 J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
HMDHMNDO_01338 9e-29 yitW S Iron-sulfur cluster assembly protein
HMDHMNDO_01339 2.4e-176 rnfC C RnfC Barrel sandwich hybrid domain
HMDHMNDO_01340 9.2e-101 selD 2.7.9.3 E AIR synthase related protein, C-terminal domain
HMDHMNDO_01341 8.3e-149 yedE S Sulphur transport
HMDHMNDO_01342 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
HMDHMNDO_01343 4.7e-35 L Helix-turn-helix domain
HMDHMNDO_01344 3.9e-68 tra L EVIDENCE BY HOMOLOGY BIO14.04 Transposon related functions. BELONGS TO THE IS30 FAMILY OF TRANSPOSASE. There are 15 such elements in the chromosome
HMDHMNDO_01345 4.6e-18 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
HMDHMNDO_01346 7.2e-58 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
HMDHMNDO_01348 3e-56 S COG NOG19168 non supervised orthologous group
HMDHMNDO_01349 1.3e-180 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HMDHMNDO_01350 6.4e-50 S Membrane
HMDHMNDO_01351 2.2e-76 rhaR K helix_turn_helix, arabinose operon control protein
HMDHMNDO_01352 1.5e-188 iolF EGP Major facilitator Superfamily
HMDHMNDO_01353 1.7e-215 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HMDHMNDO_01354 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HMDHMNDO_01355 1.8e-218 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HMDHMNDO_01356 1.5e-109 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HMDHMNDO_01358 4.1e-189 XK27_11280 S Psort location CytoplasmicMembrane, score
HMDHMNDO_01359 6.1e-11 L Plasmid pRiA4b ORF-3-like protein
HMDHMNDO_01360 1.2e-105 L Belongs to the 'phage' integrase family
HMDHMNDO_01361 5.6e-18 3.1.21.3 V Type I restriction modification DNA specificity domain
HMDHMNDO_01362 6.6e-60 hsdM 2.1.1.72 V type I restriction-modification system
HMDHMNDO_01364 2.3e-125 L T/G mismatch-specific endonuclease activity
HMDHMNDO_01365 4.5e-20 L T/G mismatch-specific endonuclease activity
HMDHMNDO_01367 4.2e-74 3.1.1.85 S Serine hydrolase
HMDHMNDO_01368 1.4e-41 L Transposase
HMDHMNDO_01369 6.9e-118 L Integrase core domain
HMDHMNDO_01370 4.5e-149 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HMDHMNDO_01371 4.5e-218 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HMDHMNDO_01372 2.1e-123 H ThiF family
HMDHMNDO_01373 6.1e-236 stp_1 EGP Major Facilitator Superfamily
HMDHMNDO_01374 1.3e-148 L An automated process has identified a potential problem with this gene model
HMDHMNDO_01382 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMDHMNDO_01383 1.4e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMDHMNDO_01384 3.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMDHMNDO_01385 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HMDHMNDO_01386 2.5e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMDHMNDO_01388 1.6e-55 ctsR K Belongs to the CtsR family
HMDHMNDO_01389 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMDHMNDO_01390 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMDHMNDO_01391 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMDHMNDO_01392 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
HMDHMNDO_01393 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMDHMNDO_01394 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMDHMNDO_01395 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMDHMNDO_01396 1.3e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HMDHMNDO_01397 1.2e-89 patB 4.4.1.8 E Aminotransferase, class I
HMDHMNDO_01398 2.5e-113 K response regulator
HMDHMNDO_01399 8.8e-143 hpk31 2.7.13.3 T Histidine kinase
HMDHMNDO_01400 2.2e-90 lacX 5.1.3.3 G Aldose 1-epimerase
HMDHMNDO_01401 1.9e-20 G Transporter, major facilitator family protein
HMDHMNDO_01402 3.7e-115 G Transporter, major facilitator family protein
HMDHMNDO_01403 7e-224 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMDHMNDO_01404 7.3e-246 yhcA V ABC transporter, ATP-binding protein
HMDHMNDO_01405 5.8e-35 K Bacterial regulatory proteins, tetR family
HMDHMNDO_01406 4.6e-37 lmrA V ABC transporter, ATP-binding protein
HMDHMNDO_01407 3.6e-172 lmrA V ABC transporter, ATP-binding protein
HMDHMNDO_01408 3.3e-253 yfiC V ABC transporter
HMDHMNDO_01410 3.2e-45 yjcF K protein acetylation
HMDHMNDO_01411 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
HMDHMNDO_01412 1.5e-71 lemA S LemA family
HMDHMNDO_01413 1.3e-114 htpX O Belongs to the peptidase M48B family
HMDHMNDO_01415 2.3e-272 helD 3.6.4.12 L DNA helicase
HMDHMNDO_01416 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMDHMNDO_01417 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMDHMNDO_01418 9.4e-103 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HMDHMNDO_01419 8.4e-83 ybhF_2 V abc transporter atp-binding protein
HMDHMNDO_01420 3.5e-104 ybhR V ABC transporter
HMDHMNDO_01421 2.3e-31 K Transcriptional regulator
HMDHMNDO_01422 7.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
HMDHMNDO_01423 2.1e-153 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HMDHMNDO_01424 4.3e-127
HMDHMNDO_01425 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMDHMNDO_01426 8.3e-105 tatD L hydrolase, TatD family
HMDHMNDO_01427 1.7e-86 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMDHMNDO_01428 7.5e-134 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMDHMNDO_01429 1.2e-22 veg S Biofilm formation stimulator VEG
HMDHMNDO_01430 1.7e-90 S Alpha/beta hydrolase of unknown function (DUF915)
HMDHMNDO_01431 4.2e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
HMDHMNDO_01432 6.6e-46 argR K Regulates arginine biosynthesis genes
HMDHMNDO_01433 2.8e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMDHMNDO_01434 2.3e-155 amtB P ammonium transporter
HMDHMNDO_01436 1.8e-92 sip L Belongs to the 'phage' integrase family
HMDHMNDO_01437 8e-104 dam2 2.1.1.72 L DNA methyltransferase
HMDHMNDO_01438 4.4e-127 S AAA ATPase domain
HMDHMNDO_01441 2.5e-40 K Peptidase S24-like
HMDHMNDO_01444 5.9e-16
HMDHMNDO_01446 7.5e-15 K Cro/C1-type HTH DNA-binding domain
HMDHMNDO_01449 1.2e-12 cro K Helix-turn-helix XRE-family like proteins
HMDHMNDO_01450 4.6e-81 S DNA binding
HMDHMNDO_01454 1.7e-54 S Putative HNHc nuclease
HMDHMNDO_01455 2.8e-28 S Phage replisome organizer, N-terminal domain protein
HMDHMNDO_01458 1.6e-25
HMDHMNDO_01459 3.7e-70
HMDHMNDO_01470 8.3e-33 arpU S Phage transcriptional regulator, ArpU family
HMDHMNDO_01471 1.3e-59 S AAA domain, putative AbiEii toxin, Type IV TA system
HMDHMNDO_01473 1.3e-08 S RloB-like protein
HMDHMNDO_01474 8.8e-12
HMDHMNDO_01477 4.4e-73 L HNH nucleases
HMDHMNDO_01478 3.6e-82 L Phage terminase, small subunit
HMDHMNDO_01479 0.0 S Phage Terminase
HMDHMNDO_01481 1.6e-192 S Phage portal protein
HMDHMNDO_01482 1e-112 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HMDHMNDO_01483 1.3e-197 S Phage capsid family
HMDHMNDO_01484 7e-21 S Phage gp6-like head-tail connector protein
HMDHMNDO_01485 1.4e-51 S Phage head-tail joining protein
HMDHMNDO_01486 4.8e-54 S Bacteriophage HK97-gp10, putative tail-component
HMDHMNDO_01487 7.8e-56 S Protein of unknown function (DUF806)
HMDHMNDO_01488 3.5e-78 S Phage tail tube protein
HMDHMNDO_01489 1.1e-15 S Phage tail assembly chaperone proteins, TAC
HMDHMNDO_01491 6.5e-280 M Phage tail tape measure protein TP901
HMDHMNDO_01492 4.6e-77 S Phage tail protein
HMDHMNDO_01493 1.3e-121 rny D peptidase
HMDHMNDO_01495 1.7e-20 S Calcineurin-like phosphoesterase
HMDHMNDO_01500 5.6e-10 hol S Bacteriophage holin
HMDHMNDO_01501 1e-131 M Glycosyl hydrolases family 25
HMDHMNDO_01502 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
HMDHMNDO_01503 1.9e-196 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMDHMNDO_01504 6.2e-152 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HMDHMNDO_01505 2.2e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMDHMNDO_01506 1.9e-104 pfoS S Phosphotransferase system, EIIC
HMDHMNDO_01507 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMDHMNDO_01508 6.6e-53 adhR K helix_turn_helix, mercury resistance
HMDHMNDO_01509 5.2e-137 purR 2.4.2.7 F pur operon repressor
HMDHMNDO_01510 2.1e-46 EGP Transmembrane secretion effector
HMDHMNDO_01511 1.1e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMDHMNDO_01512 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMDHMNDO_01513 7.7e-19 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMDHMNDO_01514 7.6e-112 dkg S reductase
HMDHMNDO_01515 1.1e-23
HMDHMNDO_01516 1e-78 2.4.2.3 F Phosphorylase superfamily
HMDHMNDO_01517 2e-289 ybiT S ABC transporter, ATP-binding protein
HMDHMNDO_01518 1.1e-62 bCE_4747 S Beta-lactamase superfamily domain
HMDHMNDO_01519 1.9e-98 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMDHMNDO_01520 1.6e-125 S overlaps another CDS with the same product name
HMDHMNDO_01521 2.2e-86 S overlaps another CDS with the same product name
HMDHMNDO_01523 3e-56 spoVK O ATPase family associated with various cellular activities (AAA)
HMDHMNDO_01524 2.3e-22
HMDHMNDO_01525 1.1e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
HMDHMNDO_01532 4.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HMDHMNDO_01533 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HMDHMNDO_01534 1.3e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMDHMNDO_01535 9.3e-161 camS S sex pheromone
HMDHMNDO_01536 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMDHMNDO_01537 4e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMDHMNDO_01538 2.8e-255 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMDHMNDO_01539 9.8e-146 yegS 2.7.1.107 G Lipid kinase
HMDHMNDO_01540 9.9e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMDHMNDO_01541 1.4e-121 L Mrr N-terminal domain
HMDHMNDO_01542 1.3e-17
HMDHMNDO_01543 1.3e-75 K phage regulatory protein, rha family
HMDHMNDO_01544 3e-22
HMDHMNDO_01545 4.1e-16
HMDHMNDO_01546 9.1e-78 L AAA domain
HMDHMNDO_01547 5.4e-19 K Cro/C1-type HTH DNA-binding domain
HMDHMNDO_01548 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HMDHMNDO_01549 1.3e-162 hsdM 2.1.1.72 V cog cog0286
HMDHMNDO_01550 3.2e-37 hsdM 2.1.1.72 V type I restriction-modification system
HMDHMNDO_01551 4.5e-86 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain protein
HMDHMNDO_01552 8.3e-126 S Bacteriophage abortive infection AbiH
HMDHMNDO_01555 1.6e-174 spoVK O ATPase family associated with various cellular activities (AAA)
HMDHMNDO_01556 3.5e-50 K Cro/C1-type HTH DNA-binding domain
HMDHMNDO_01558 5.2e-65 S Acetyltransferase (GNAT) domain
HMDHMNDO_01559 5.1e-72 ywlG S Belongs to the UPF0340 family
HMDHMNDO_01560 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HMDHMNDO_01561 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMDHMNDO_01562 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMDHMNDO_01563 1.4e-176 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HMDHMNDO_01564 2e-14 ybaN S Protein of unknown function (DUF454)
HMDHMNDO_01565 3.9e-238 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMDHMNDO_01566 7.2e-200 frdC 1.3.5.4 C FAD binding domain
HMDHMNDO_01567 1.5e-205 yflS P Sodium:sulfate symporter transmembrane region
HMDHMNDO_01568 4.6e-36 yncA 2.3.1.79 S Maltose acetyltransferase
HMDHMNDO_01569 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMDHMNDO_01570 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
HMDHMNDO_01571 1.9e-95 ypuA S Protein of unknown function (DUF1002)
HMDHMNDO_01573 1.4e-113 3.2.1.18 GH33 M Rib/alpha-like repeat
HMDHMNDO_01574 2.1e-116 3.2.1.18 GH33 M Rib/alpha-like repeat
HMDHMNDO_01575 8.1e-44 K Copper transport repressor CopY TcrY
HMDHMNDO_01576 6.1e-60 T Belongs to the universal stress protein A family
HMDHMNDO_01577 5.9e-41 K Bacterial regulatory proteins, tetR family
HMDHMNDO_01578 1.1e-56 K transcriptional
HMDHMNDO_01579 1.8e-71 mleR K LysR family
HMDHMNDO_01580 4.9e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HMDHMNDO_01581 1.7e-126 mleP S Sodium Bile acid symporter family
HMDHMNDO_01582 5.5e-64 S ECF transporter, substrate-specific component
HMDHMNDO_01583 1.6e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
HMDHMNDO_01584 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMDHMNDO_01585 6.3e-193 pbuX F xanthine permease
HMDHMNDO_01586 1.7e-35 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HMDHMNDO_01587 9e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMDHMNDO_01588 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
HMDHMNDO_01589 1.3e-116 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMDHMNDO_01590 1.3e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HMDHMNDO_01591 8.8e-158 mgtE P Acts as a magnesium transporter
HMDHMNDO_01593 1.7e-40
HMDHMNDO_01594 9.7e-35 K GNAT family
HMDHMNDO_01595 6.4e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HMDHMNDO_01596 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HMDHMNDO_01597 4.9e-42 O ADP-ribosylglycohydrolase
HMDHMNDO_01598 3.6e-220 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HMDHMNDO_01599 2.8e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMDHMNDO_01600 4.2e-161 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMDHMNDO_01601 4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HMDHMNDO_01602 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HMDHMNDO_01603 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMDHMNDO_01604 1.4e-174 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HMDHMNDO_01605 2e-24 S Domain of unknown function (DUF4828)
HMDHMNDO_01606 7e-128 mocA S Oxidoreductase
HMDHMNDO_01607 2.6e-159 yfmL L DEAD DEAH box helicase
HMDHMNDO_01608 2e-20 S Domain of unknown function (DUF3284)
HMDHMNDO_01610 2.3e-279 kup P Transport of potassium into the cell
HMDHMNDO_01611 4.2e-101 malR K Transcriptional regulator, LacI family
HMDHMNDO_01612 4.3e-213 malT G Transporter, major facilitator family protein
HMDHMNDO_01613 2.9e-78 galM 5.1.3.3 G Aldose 1-epimerase
HMDHMNDO_01614 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HMDHMNDO_01615 4.9e-85 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HMDHMNDO_01616 3e-266 E Amino acid permease
HMDHMNDO_01617 6.7e-181 pepS E Thermophilic metalloprotease (M29)
HMDHMNDO_01618 9.3e-169 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMDHMNDO_01619 1.1e-70 K Sugar-specific transcriptional regulator TrmB
HMDHMNDO_01620 1.7e-122 S Sulfite exporter TauE/SafE
HMDHMNDO_01621 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
HMDHMNDO_01622 0.0 S Bacterial membrane protein YfhO
HMDHMNDO_01623 8.7e-53 gtcA S Teichoic acid glycosylation protein
HMDHMNDO_01624 5.1e-54 fld C Flavodoxin
HMDHMNDO_01625 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
HMDHMNDO_01626 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMDHMNDO_01627 2.8e-12 mltD CBM50 M Lysin motif
HMDHMNDO_01628 2.9e-93 yihY S Belongs to the UPF0761 family
HMDHMNDO_01632 3.9e-10
HMDHMNDO_01633 8.5e-74 V domain protein
HMDHMNDO_01634 1e-87 V domain protein
HMDHMNDO_01635 1.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
HMDHMNDO_01636 1.6e-17
HMDHMNDO_01637 1.1e-104 azlC E AzlC protein
HMDHMNDO_01638 1.3e-38 azlD S branched-chain amino acid
HMDHMNDO_01639 2.4e-65 I alpha/beta hydrolase fold
HMDHMNDO_01640 2.4e-25
HMDHMNDO_01641 1.2e-58 3.6.1.27 I phosphatase
HMDHMNDO_01642 5.4e-23
HMDHMNDO_01643 2.9e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HMDHMNDO_01644 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
HMDHMNDO_01645 3.1e-27 cspC K Cold shock protein
HMDHMNDO_01646 1.3e-81 thrE S Putative threonine/serine exporter
HMDHMNDO_01647 2.8e-49 S Threonine/Serine exporter, ThrE
HMDHMNDO_01648 3.2e-121 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMDHMNDO_01649 4.9e-87 S Sucrose-6F-phosphate phosphohydrolase
HMDHMNDO_01650 1.9e-34 trxA O Belongs to the thioredoxin family
HMDHMNDO_01651 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMDHMNDO_01652 2e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMDHMNDO_01653 7.3e-65 degV S Uncharacterised protein, DegV family COG1307
HMDHMNDO_01655 4.3e-54 queT S QueT transporter
HMDHMNDO_01656 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
HMDHMNDO_01657 5e-102 IQ Enoyl-(Acyl carrier protein) reductase
HMDHMNDO_01658 4.6e-112 argE 3.5.1.18 E Peptidase dimerisation domain
HMDHMNDO_01659 2.5e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMDHMNDO_01660 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMDHMNDO_01661 5e-87 S Alpha beta hydrolase
HMDHMNDO_01662 1.6e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMDHMNDO_01663 3.6e-140 V MatE
HMDHMNDO_01664 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
HMDHMNDO_01665 2.2e-63 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMDHMNDO_01666 9.6e-97 V ABC transporter
HMDHMNDO_01667 9.6e-132 bacI V MacB-like periplasmic core domain
HMDHMNDO_01668 3.7e-75 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMDHMNDO_01669 4.8e-26
HMDHMNDO_01670 2.1e-180 yhdP S Transporter associated domain
HMDHMNDO_01671 2.7e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
HMDHMNDO_01672 0.0 L Helicase C-terminal domain protein
HMDHMNDO_01673 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMDHMNDO_01674 6.3e-212 yfnA E Amino Acid
HMDHMNDO_01675 9.2e-53 zur P Belongs to the Fur family
HMDHMNDO_01676 3e-12 3.2.1.14 GH18
HMDHMNDO_01677 5e-98
HMDHMNDO_01678 1.3e-09
HMDHMNDO_01679 3.7e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMDHMNDO_01680 1.9e-99 glnH ET ABC transporter
HMDHMNDO_01681 1.2e-85 gluC P ABC transporter permease
HMDHMNDO_01682 9.6e-78 glnP P ABC transporter permease
HMDHMNDO_01683 9e-184 steT E amino acid
HMDHMNDO_01684 6.5e-21 K Acetyltransferase (GNAT) domain
HMDHMNDO_01685 2.1e-145 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HMDHMNDO_01686 2.6e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HMDHMNDO_01687 2.5e-78 K rpiR family
HMDHMNDO_01688 4.3e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMDHMNDO_01689 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HMDHMNDO_01690 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMDHMNDO_01691 1e-100 rplD J Forms part of the polypeptide exit tunnel
HMDHMNDO_01692 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMDHMNDO_01693 4.1e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMDHMNDO_01694 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMDHMNDO_01695 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMDHMNDO_01696 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMDHMNDO_01697 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMDHMNDO_01698 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HMDHMNDO_01699 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMDHMNDO_01700 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMDHMNDO_01701 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMDHMNDO_01702 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMDHMNDO_01703 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMDHMNDO_01704 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMDHMNDO_01705 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMDHMNDO_01706 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMDHMNDO_01707 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMDHMNDO_01708 2.1e-22 rpmD J Ribosomal protein L30
HMDHMNDO_01709 1e-67 rplO J Binds to the 23S rRNA
HMDHMNDO_01710 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMDHMNDO_01711 3.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMDHMNDO_01712 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMDHMNDO_01713 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HMDHMNDO_01714 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMDHMNDO_01715 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMDHMNDO_01716 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMDHMNDO_01717 4.8e-53 rplQ J Ribosomal protein L17
HMDHMNDO_01718 1.8e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMDHMNDO_01719 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMDHMNDO_01720 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMDHMNDO_01721 2.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMDHMNDO_01722 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMDHMNDO_01723 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
HMDHMNDO_01724 5.7e-28
HMDHMNDO_01725 3.1e-246 yjbQ P TrkA C-terminal domain protein
HMDHMNDO_01726 0.0 helD 3.6.4.12 L DNA helicase
HMDHMNDO_01727 4e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HMDHMNDO_01728 2.6e-109 hrtB V ABC transporter permease
HMDHMNDO_01729 1.9e-33 ygfC K transcriptional regulator (TetR family)
HMDHMNDO_01730 1.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HMDHMNDO_01731 1.1e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HMDHMNDO_01732 6.8e-35 M LysM domain protein
HMDHMNDO_01733 9.8e-115 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMDHMNDO_01734 7.9e-106 sbcC L Putative exonuclease SbcCD, C subunit
HMDHMNDO_01735 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
HMDHMNDO_01736 7.2e-53 perR P Belongs to the Fur family
HMDHMNDO_01737 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMDHMNDO_01738 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMDHMNDO_01739 2.5e-86 S (CBS) domain
HMDHMNDO_01740 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMDHMNDO_01741 2.2e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMDHMNDO_01742 8.9e-145 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMDHMNDO_01743 4.1e-308 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMDHMNDO_01744 2.8e-139 yabM S Polysaccharide biosynthesis protein
HMDHMNDO_01745 3.6e-31 yabO J S4 domain protein
HMDHMNDO_01746 1e-21 divIC D Septum formation initiator
HMDHMNDO_01747 1.1e-40 yabR J RNA binding
HMDHMNDO_01748 1.9e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMDHMNDO_01749 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMDHMNDO_01750 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMDHMNDO_01751 7.8e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMDHMNDO_01752 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMDHMNDO_01753 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HMDHMNDO_01754 5.1e-86 S Fic/DOC family
HMDHMNDO_01755 2.2e-11 S sequence-specific DNA binding
HMDHMNDO_01756 6.6e-11 3.4.21.88 K Peptidase S24-like
HMDHMNDO_01761 1.4e-09 S Arc-like DNA binding domain
HMDHMNDO_01763 1e-20 S Replication initiator protein A (RepA) N-terminus
HMDHMNDO_01768 1.5e-08
HMDHMNDO_01773 7.5e-20
HMDHMNDO_01774 1.9e-11 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
HMDHMNDO_01778 2.3e-61 ruvB 3.6.4.12 L four-way junction helicase activity
HMDHMNDO_01780 1e-10
HMDHMNDO_01782 4.8e-78 S Fic/DOC family
HMDHMNDO_01784 5.7e-66 D nuclear chromosome segregation
HMDHMNDO_01785 7.5e-08
HMDHMNDO_01786 1.2e-61 gepA K Protein of unknown function (DUF4065)
HMDHMNDO_01787 1.6e-28
HMDHMNDO_01788 5.4e-19 Z012_06740 S Fic/DOC family
HMDHMNDO_01790 6.5e-07
HMDHMNDO_01791 8.7e-63 sip L Belongs to the 'phage' integrase family
HMDHMNDO_01792 1.5e-29
HMDHMNDO_01793 2.3e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HMDHMNDO_01794 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMDHMNDO_01795 1.8e-08 K transcriptional
HMDHMNDO_01796 3.4e-10 S Protein of unknown function (DUF805)
HMDHMNDO_01798 1.5e-78 yvfR V ABC transporter
HMDHMNDO_01799 1.9e-53 yvfS V ABC-2 type transporter
HMDHMNDO_01800 5.4e-57 salK 2.7.13.3 T Histidine kinase
HMDHMNDO_01801 2.1e-63 desR K helix_turn_helix, Lux Regulon
HMDHMNDO_01802 1.4e-70 ptp3 3.1.3.48 T Tyrosine phosphatase family
HMDHMNDO_01803 1.6e-90 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HMDHMNDO_01807 1.4e-142 xerS L Phage integrase family
HMDHMNDO_01808 3.8e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HMDHMNDO_01809 6.5e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMDHMNDO_01810 1.6e-217 1.3.5.4 C FAD binding domain
HMDHMNDO_01811 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
HMDHMNDO_01812 1.6e-138 G Xylose isomerase-like TIM barrel
HMDHMNDO_01813 1.3e-72 K Transcriptional regulator, LysR family
HMDHMNDO_01814 1.4e-98 EGP Major Facilitator Superfamily
HMDHMNDO_01815 2.6e-129 EGP Major Facilitator Superfamily
HMDHMNDO_01816 2.7e-81 L Integrase core domain
HMDHMNDO_01817 1.8e-20 L PFAM transposase IS3 IS911 family protein
HMDHMNDO_01818 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HMDHMNDO_01819 1.7e-32 P Heavy-metal-associated domain
HMDHMNDO_01820 7.1e-17 tnp L Transposase IS66 family
HMDHMNDO_01821 3.4e-19 tnp
HMDHMNDO_01822 5.8e-44 L hmm pf00665
HMDHMNDO_01823 1.1e-98 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HMDHMNDO_01824 1.2e-84 dps P Ferritin-like domain
HMDHMNDO_01825 2e-159 L transposase, IS605 OrfB family
HMDHMNDO_01826 1.2e-57 tlpA2 L Transposase IS200 like
HMDHMNDO_01827 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
HMDHMNDO_01829 9e-102 qmcA O prohibitin homologues
HMDHMNDO_01830 4.7e-26 S protein encoded in hypervariable junctions of pilus gene clusters
HMDHMNDO_01831 0.0 O Belongs to the peptidase S8 family
HMDHMNDO_01832 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMDHMNDO_01833 7.3e-118 O AAA domain (Cdc48 subfamily)
HMDHMNDO_01834 4.1e-67
HMDHMNDO_01835 8.6e-90 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
HMDHMNDO_01836 4e-225 hsdM 2.1.1.72 V type I restriction-modification system
HMDHMNDO_01837 2.4e-286 hsdR 3.1.21.3 L DEAD/DEAH box helicase
HMDHMNDO_01838 4.4e-07
HMDHMNDO_01839 1.1e-45 yjaB_1 K Acetyltransferase (GNAT) domain
HMDHMNDO_01840 3.5e-80 yitS S EDD domain protein, DegV family
HMDHMNDO_01841 1.9e-57 racA K Domain of unknown function (DUF1836)
HMDHMNDO_01842 2.7e-116 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HMDHMNDO_01843 2.7e-48 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HMDHMNDO_01844 5.4e-87 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HMDHMNDO_01845 1.3e-161 potE2 E amino acid
HMDHMNDO_01848 4.6e-24
HMDHMNDO_01849 6.9e-15
HMDHMNDO_01850 7.4e-92 pstS P T5orf172
HMDHMNDO_01851 2.4e-257 yeeB L DEAD-like helicases superfamily
HMDHMNDO_01852 1.9e-217 yeeA V Type II restriction enzyme, methylase subunits
HMDHMNDO_01853 1.8e-14 yeeA V Type II restriction enzyme, methylase subunits
HMDHMNDO_01854 6.9e-60 yeeA V Type II restriction enzyme, methylase subunits
HMDHMNDO_01855 3.3e-64
HMDHMNDO_01856 1.5e-46
HMDHMNDO_01857 7.8e-38 K transcriptional regulator PadR family
HMDHMNDO_01858 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
HMDHMNDO_01859 1.2e-15 S Putative adhesin
HMDHMNDO_01860 2.2e-16 pspC KT PspC domain
HMDHMNDO_01862 5.1e-13 S Enterocin A Immunity
HMDHMNDO_01863 4e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMDHMNDO_01864 1.3e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HMDHMNDO_01865 4.3e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HMDHMNDO_01866 1.1e-166 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMDHMNDO_01867 1.5e-120 potB P ABC transporter permease
HMDHMNDO_01868 4.5e-104 potC U Binding-protein-dependent transport system inner membrane component
HMDHMNDO_01869 1.3e-159 potD P ABC transporter
HMDHMNDO_01870 3.5e-132 ABC-SBP S ABC transporter
HMDHMNDO_01871 3.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HMDHMNDO_01872 6.7e-107 XK27_08845 S ABC transporter, ATP-binding protein
HMDHMNDO_01873 2.8e-66 M ErfK YbiS YcfS YnhG
HMDHMNDO_01874 1.2e-53 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMDHMNDO_01875 4.2e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMDHMNDO_01876 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMDHMNDO_01877 1.2e-102 pgm3 G phosphoglycerate mutase
HMDHMNDO_01878 4.7e-56 S CAAX protease self-immunity
HMDHMNDO_01879 2.2e-47 C Flavodoxin
HMDHMNDO_01880 9.7e-60 yphH S Cupin domain
HMDHMNDO_01881 3.6e-46 yphJ 4.1.1.44 S decarboxylase
HMDHMNDO_01882 2.9e-143 E methionine synthase, vitamin-B12 independent
HMDHMNDO_01883 3.7e-106 metQ1 P Belongs to the nlpA lipoprotein family
HMDHMNDO_01884 1.5e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMDHMNDO_01885 2.7e-70 metI P ABC transporter permease
HMDHMNDO_01886 3.3e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HMDHMNDO_01887 3e-84 drgA C nitroreductase
HMDHMNDO_01888 2.5e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HMDHMNDO_01889 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HMDHMNDO_01890 8.1e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HMDHMNDO_01891 1.4e-263 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HMDHMNDO_01893 2.3e-150 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMDHMNDO_01894 2.4e-31 metI U ABC transporter permease
HMDHMNDO_01895 1.6e-127 metQ M Belongs to the nlpA lipoprotein family
HMDHMNDO_01896 1.8e-53 S Protein of unknown function (DUF4256)
HMDHMNDO_01899 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HMDHMNDO_01900 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HMDHMNDO_01901 2.6e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMDHMNDO_01902 4e-230 lpdA 1.8.1.4 C Dehydrogenase
HMDHMNDO_01903 2.1e-148 lplA 6.3.1.20 H Lipoate-protein ligase
HMDHMNDO_01904 9.2e-56 S Protein of unknown function (DUF975)
HMDHMNDO_01905 5.7e-78 E GDSL-like Lipase/Acylhydrolase family
HMDHMNDO_01906 1.4e-38
HMDHMNDO_01907 4.1e-27 gcvR T Belongs to the UPF0237 family
HMDHMNDO_01908 6.1e-220 XK27_08635 S UPF0210 protein
HMDHMNDO_01909 4.5e-87 fruR K DeoR C terminal sensor domain
HMDHMNDO_01910 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMDHMNDO_01911 4.8e-282 fruA 2.7.1.202 GT Phosphotransferase System
HMDHMNDO_01912 5.5e-144 dapE 3.5.1.18 E Peptidase dimerisation domain
HMDHMNDO_01913 1e-149 E glutamate:sodium symporter activity
HMDHMNDO_01914 1.2e-145 Q Imidazolonepropionase and related amidohydrolases
HMDHMNDO_01915 9.1e-50 cps3F
HMDHMNDO_01916 3e-82 S Membrane
HMDHMNDO_01917 1.8e-254 E Amino acid permease
HMDHMNDO_01918 2.9e-225 cadA P P-type ATPase
HMDHMNDO_01919 6.4e-114 degV S EDD domain protein, DegV family
HMDHMNDO_01920 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HMDHMNDO_01921 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
HMDHMNDO_01922 7.2e-27 ydiI Q Thioesterase superfamily
HMDHMNDO_01923 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HMDHMNDO_01924 3.5e-141 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HMDHMNDO_01925 5.6e-82 S L,D-transpeptidase catalytic domain
HMDHMNDO_01926 8.8e-166 EGP Major facilitator Superfamily
HMDHMNDO_01927 2.3e-21 K helix_turn_helix multiple antibiotic resistance protein
HMDHMNDO_01928 1.7e-225 pipD E Dipeptidase
HMDHMNDO_01929 4.1e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMDHMNDO_01930 2.6e-32 ywjH S Protein of unknown function (DUF1634)
HMDHMNDO_01931 6.5e-119 yxaA S membrane transporter protein
HMDHMNDO_01932 1.7e-82 lysR5 K LysR substrate binding domain
HMDHMNDO_01933 7.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
HMDHMNDO_01934 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMDHMNDO_01935 7.3e-271 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HMDHMNDO_01936 2.3e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HMDHMNDO_01937 1.9e-243 lysP E amino acid
HMDHMNDO_01938 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMDHMNDO_01939 2.6e-29 yqkB S Belongs to the HesB IscA family
HMDHMNDO_01940 2.3e-65 yxkH G Polysaccharide deacetylase
HMDHMNDO_01941 9.6e-09
HMDHMNDO_01942 2.9e-53 K LysR substrate binding domain
HMDHMNDO_01943 2e-122 MA20_14895 S Conserved hypothetical protein 698
HMDHMNDO_01944 1.1e-199 nupG F Nucleoside
HMDHMNDO_01945 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMDHMNDO_01946 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMDHMNDO_01947 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HMDHMNDO_01948 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMDHMNDO_01949 3.9e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMDHMNDO_01950 9e-20 yaaA S S4 domain protein YaaA
HMDHMNDO_01951 9.3e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMDHMNDO_01952 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMDHMNDO_01953 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMDHMNDO_01954 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
HMDHMNDO_01955 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMDHMNDO_01956 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMDHMNDO_01957 2.5e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HMDHMNDO_01958 9.5e-117 S Glycosyl transferase family 2
HMDHMNDO_01959 7.4e-64 D peptidase
HMDHMNDO_01960 0.0 asnB 6.3.5.4 E Asparagine synthase
HMDHMNDO_01961 3.7e-37 yiiE S Protein of unknown function (DUF1211)
HMDHMNDO_01962 3.3e-12 yiiE S Protein of unknown function (DUF1211)
HMDHMNDO_01963 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMDHMNDO_01964 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HMDHMNDO_01965 3.6e-17 yneR
HMDHMNDO_01966 1.5e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMDHMNDO_01967 2.2e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
HMDHMNDO_01968 3.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HMDHMNDO_01969 3.8e-152 mdtG EGP Major facilitator Superfamily
HMDHMNDO_01970 3.8e-14 yobS K transcriptional regulator
HMDHMNDO_01971 2.8e-109 glcU U sugar transport
HMDHMNDO_01972 4.4e-170 yjjP S Putative threonine/serine exporter
HMDHMNDO_01973 2.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
HMDHMNDO_01974 2.2e-96 yicL EG EamA-like transporter family
HMDHMNDO_01975 4.6e-223 pepF E Oligopeptidase F
HMDHMNDO_01976 1.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMDHMNDO_01977 4.4e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HMDHMNDO_01978 1.1e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
HMDHMNDO_01979 8.4e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HMDHMNDO_01980 4e-23 relB L RelB antitoxin
HMDHMNDO_01982 9.8e-173 S Putative peptidoglycan binding domain
HMDHMNDO_01983 1.2e-31 K Transcriptional regulator, MarR family
HMDHMNDO_01984 3.1e-216 XK27_09600 V ABC transporter, ATP-binding protein
HMDHMNDO_01985 1.1e-229 V ABC transporter transmembrane region
HMDHMNDO_01987 3.3e-96 S Domain of unknown function DUF87
HMDHMNDO_01989 6.3e-85 yxeH S hydrolase
HMDHMNDO_01990 9e-114 K response regulator
HMDHMNDO_01991 1.1e-272 vicK 2.7.13.3 T Histidine kinase
HMDHMNDO_01992 4.6e-103 yycH S YycH protein
HMDHMNDO_01993 5.6e-80 yycI S YycH protein
HMDHMNDO_01994 1.8e-30 yyaQ S YjbR
HMDHMNDO_01995 1.3e-116 vicX 3.1.26.11 S domain protein
HMDHMNDO_01996 3.7e-145 htrA 3.4.21.107 O serine protease
HMDHMNDO_01997 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMDHMNDO_01998 4.4e-40 1.6.5.2 GM NAD(P)H-binding
HMDHMNDO_01999 3.3e-25 K MarR family transcriptional regulator
HMDHMNDO_02000 5.9e-88 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
HMDHMNDO_02001 1.7e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMDHMNDO_02002 4.2e-208 G glycerol-3-phosphate transporter
HMDHMNDO_02003 5.9e-30 L Helix-turn-helix domain
HMDHMNDO_02004 3.6e-69 L HTH-like domain
HMDHMNDO_02005 2.1e-71 L PFAM transposase IS200-family protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)