ORF_ID e_value Gene_name EC_number CAZy COGs Description
HACEDBDI_00001 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HACEDBDI_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HACEDBDI_00003 2.4e-33 yaaA S S4 domain
HACEDBDI_00004 9.2e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HACEDBDI_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
HACEDBDI_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HACEDBDI_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HACEDBDI_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
HACEDBDI_00011 4.3e-180 yaaC S YaaC-like Protein
HACEDBDI_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HACEDBDI_00013 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HACEDBDI_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HACEDBDI_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HACEDBDI_00016 8.1e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HACEDBDI_00017 1.3e-09
HACEDBDI_00018 8.3e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HACEDBDI_00019 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HACEDBDI_00020 2e-212 yaaH M Glycoside Hydrolase Family
HACEDBDI_00021 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
HACEDBDI_00022 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HACEDBDI_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HACEDBDI_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HACEDBDI_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HACEDBDI_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HACEDBDI_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HACEDBDI_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
HACEDBDI_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
HACEDBDI_00032 1.1e-75 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HACEDBDI_00033 4.9e-202 yaaN P Belongs to the TelA family
HACEDBDI_00034 2.3e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HACEDBDI_00035 6.9e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HACEDBDI_00036 2.2e-54 yaaQ S protein conserved in bacteria
HACEDBDI_00037 1.5e-71 yaaR S protein conserved in bacteria
HACEDBDI_00038 1.1e-181 holB 2.7.7.7 L DNA polymerase III
HACEDBDI_00039 6.1e-146 yaaT S stage 0 sporulation protein
HACEDBDI_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
HACEDBDI_00041 1.2e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
HACEDBDI_00042 7.3e-49 yazA L endonuclease containing a URI domain
HACEDBDI_00043 5.1e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HACEDBDI_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HACEDBDI_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HACEDBDI_00046 1.2e-143 tatD L hydrolase, TatD
HACEDBDI_00047 2e-167 rpfB GH23 T protein conserved in bacteria
HACEDBDI_00048 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HACEDBDI_00049 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HACEDBDI_00050 1.2e-136 yabG S peptidase
HACEDBDI_00051 7.8e-39 veg S protein conserved in bacteria
HACEDBDI_00052 8.3e-27 sspF S DNA topological change
HACEDBDI_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HACEDBDI_00054 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HACEDBDI_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HACEDBDI_00056 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HACEDBDI_00057 1.2e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HACEDBDI_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HACEDBDI_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HACEDBDI_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HACEDBDI_00061 2.4e-39 yabK S Peptide ABC transporter permease
HACEDBDI_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HACEDBDI_00063 1.5e-92 spoVT K stage V sporulation protein
HACEDBDI_00064 2.5e-281 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HACEDBDI_00065 5.6e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HACEDBDI_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HACEDBDI_00067 1.5e-49 yabP S Sporulation protein YabP
HACEDBDI_00068 4e-105 yabQ S spore cortex biosynthesis protein
HACEDBDI_00069 1.1e-44 divIC D Septum formation initiator
HACEDBDI_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HACEDBDI_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HACEDBDI_00074 2.9e-123 yabS S protein containing a von Willebrand factor type A (vWA) domain
HACEDBDI_00075 3.7e-185 KLT serine threonine protein kinase
HACEDBDI_00076 4.7e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HACEDBDI_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HACEDBDI_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HACEDBDI_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HACEDBDI_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HACEDBDI_00081 6.5e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HACEDBDI_00082 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HACEDBDI_00083 4.8e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HACEDBDI_00084 2.8e-105 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HACEDBDI_00085 6.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HACEDBDI_00086 6.5e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HACEDBDI_00087 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HACEDBDI_00088 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HACEDBDI_00089 4.1e-30 yazB K transcriptional
HACEDBDI_00090 3.2e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HACEDBDI_00091 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HACEDBDI_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
HACEDBDI_00097 2e-08
HACEDBDI_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
HACEDBDI_00103 2.9e-76 ctsR K Belongs to the CtsR family
HACEDBDI_00104 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HACEDBDI_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HACEDBDI_00106 0.0 clpC O Belongs to the ClpA ClpB family
HACEDBDI_00107 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HACEDBDI_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HACEDBDI_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HACEDBDI_00110 7.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HACEDBDI_00111 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HACEDBDI_00112 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HACEDBDI_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HACEDBDI_00114 9.3e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HACEDBDI_00115 2.3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HACEDBDI_00116 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HACEDBDI_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HACEDBDI_00118 4.4e-115 sigH K Belongs to the sigma-70 factor family
HACEDBDI_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HACEDBDI_00120 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HACEDBDI_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HACEDBDI_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HACEDBDI_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HACEDBDI_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HACEDBDI_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
HACEDBDI_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HACEDBDI_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HACEDBDI_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HACEDBDI_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HACEDBDI_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HACEDBDI_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HACEDBDI_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HACEDBDI_00133 2.4e-178 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HACEDBDI_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HACEDBDI_00135 1.2e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HACEDBDI_00136 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
HACEDBDI_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HACEDBDI_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HACEDBDI_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HACEDBDI_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HACEDBDI_00141 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HACEDBDI_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HACEDBDI_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HACEDBDI_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HACEDBDI_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HACEDBDI_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HACEDBDI_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HACEDBDI_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HACEDBDI_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HACEDBDI_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HACEDBDI_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HACEDBDI_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HACEDBDI_00153 1.9e-23 rpmD J Ribosomal protein L30
HACEDBDI_00154 1.8e-72 rplO J binds to the 23S rRNA
HACEDBDI_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HACEDBDI_00156 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HACEDBDI_00157 6.3e-142 map 3.4.11.18 E Methionine aminopeptidase
HACEDBDI_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HACEDBDI_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HACEDBDI_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HACEDBDI_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HACEDBDI_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HACEDBDI_00163 3.6e-58 rplQ J Ribosomal protein L17
HACEDBDI_00164 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HACEDBDI_00165 1.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HACEDBDI_00166 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HACEDBDI_00167 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HACEDBDI_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HACEDBDI_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HACEDBDI_00170 8.4e-114 sip L Belongs to the 'phage' integrase family
HACEDBDI_00171 3.1e-61 E IrrE N-terminal-like domain
HACEDBDI_00172 4.8e-54 K Cro/C1-type HTH DNA-binding domain
HACEDBDI_00173 4.4e-20
HACEDBDI_00174 8.1e-23
HACEDBDI_00179 1.7e-81
HACEDBDI_00180 4.5e-21 S Uncharacterized protein YqaH
HACEDBDI_00182 2.6e-92 S DNA protection
HACEDBDI_00183 2e-161 tadZ D AAA domain
HACEDBDI_00184 1.3e-75 S Protein of unknown function (DUF669)
HACEDBDI_00185 0.0 S D5 N terminal like
HACEDBDI_00187 2.3e-75
HACEDBDI_00188 7.1e-95 S ERCC4 domain
HACEDBDI_00190 8.7e-82
HACEDBDI_00192 5.8e-59
HACEDBDI_00195 6.7e-28 L HNH endonuclease
HACEDBDI_00196 1.3e-16
HACEDBDI_00197 5e-174 S Phage Terminase
HACEDBDI_00198 3.3e-113 S Phage portal protein
HACEDBDI_00199 1.6e-47 S Caudovirus prohead serine protease
HACEDBDI_00200 4e-96 S Phage capsid family
HACEDBDI_00201 5.9e-11 S Phage gp6-like head-tail connector protein
HACEDBDI_00202 9.4e-08 S head-tail adaptor
HACEDBDI_00203 7.2e-15 S Bacteriophage HK97-gp10, putative tail-component
HACEDBDI_00204 1.9e-17
HACEDBDI_00205 2.5e-54 S phage major tail protein, phi13 family
HACEDBDI_00207 7.5e-147 D Phage-related minor tail protein
HACEDBDI_00208 8.8e-44 S Phage tail protein
HACEDBDI_00209 1.9e-102 mur1 NU Prophage endopeptidase tail
HACEDBDI_00210 6.2e-61
HACEDBDI_00211 2.4e-54 S Domain of unknown function (DUF2479)
HACEDBDI_00214 2.1e-57 S Bacteriophage holin family
HACEDBDI_00215 2.8e-110 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HACEDBDI_00218 2.7e-12
HACEDBDI_00219 1.9e-08
HACEDBDI_00220 4.5e-143 ybaJ Q Methyltransferase domain
HACEDBDI_00221 6.3e-65 ybaK S Protein of unknown function (DUF2521)
HACEDBDI_00222 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HACEDBDI_00223 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HACEDBDI_00224 1.2e-84 gerD
HACEDBDI_00225 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HACEDBDI_00226 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HACEDBDI_00227 3.4e-39 S COG NOG14552 non supervised orthologous group
HACEDBDI_00230 2e-08
HACEDBDI_00234 3.4e-39 S COG NOG14552 non supervised orthologous group
HACEDBDI_00235 3.4e-39 S COG NOG14552 non supervised orthologous group
HACEDBDI_00236 1.6e-247 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HACEDBDI_00237 3e-160 ybaS 1.1.1.58 S Na -dependent transporter
HACEDBDI_00238 2.5e-56 ybbA S Putative esterase
HACEDBDI_00239 1.4e-118 aacC 2.3.1.81 V aminoglycoside
HACEDBDI_00240 7e-47 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
HACEDBDI_00241 5.9e-50 2.7.7.73, 2.7.7.80 H ThiF family
HACEDBDI_00242 1.6e-45
HACEDBDI_00243 2.6e-63 S Major Facilitator Superfamily
HACEDBDI_00244 2e-56 1.14.11.27 S JmjC domain, hydroxylase
HACEDBDI_00245 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACEDBDI_00246 6.9e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACEDBDI_00247 4e-165 feuA P Iron-uptake system-binding protein
HACEDBDI_00248 4.2e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HACEDBDI_00249 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
HACEDBDI_00250 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HACEDBDI_00251 4.3e-250 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HACEDBDI_00252 2.2e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACEDBDI_00253 1.2e-149 ybbH K transcriptional
HACEDBDI_00254 5.1e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HACEDBDI_00255 1.9e-86 ybbJ J acetyltransferase
HACEDBDI_00256 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HACEDBDI_00262 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HACEDBDI_00263 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HACEDBDI_00264 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HACEDBDI_00265 1.5e-224 ybbR S protein conserved in bacteria
HACEDBDI_00266 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HACEDBDI_00267 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HACEDBDI_00268 5.5e-172 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HACEDBDI_00269 3.9e-116 adaA 3.2.2.21 K Transcriptional regulator
HACEDBDI_00270 9e-98 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HACEDBDI_00271 5.9e-272 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HACEDBDI_00272 0.0 ybcC S Belongs to the UPF0753 family
HACEDBDI_00273 1.7e-93 can 4.2.1.1 P carbonic anhydrase
HACEDBDI_00275 8.7e-47
HACEDBDI_00276 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HACEDBDI_00277 5.1e-50 ybzH K Helix-turn-helix domain
HACEDBDI_00278 1.9e-201 ybcL EGP Major facilitator Superfamily
HACEDBDI_00279 7e-56
HACEDBDI_00280 5.8e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HACEDBDI_00281 4.2e-121 T Transcriptional regulatory protein, C terminal
HACEDBDI_00282 5.9e-172 T His Kinase A (phospho-acceptor) domain
HACEDBDI_00284 5.1e-139 KLT Protein tyrosine kinase
HACEDBDI_00285 3.8e-151 ybdN
HACEDBDI_00286 3.6e-216 ybdO S Domain of unknown function (DUF4885)
HACEDBDI_00287 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HACEDBDI_00288 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HACEDBDI_00289 4.1e-29 ybxH S Family of unknown function (DUF5370)
HACEDBDI_00290 2.6e-149 ybxI 3.5.2.6 V beta-lactamase
HACEDBDI_00291 2.3e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HACEDBDI_00292 4.9e-41 ybyB
HACEDBDI_00293 1.8e-290 ybeC E amino acid
HACEDBDI_00294 9.3e-161 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HACEDBDI_00295 7.3e-258 glpT G -transporter
HACEDBDI_00296 1.5e-34 S Protein of unknown function (DUF2651)
HACEDBDI_00297 3.3e-169 ybfA 3.4.15.5 K FR47-like protein
HACEDBDI_00298 2.1e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
HACEDBDI_00299 6.3e-160 ybfH EG EamA-like transporter family
HACEDBDI_00300 2.3e-145 msmR K AraC-like ligand binding domain
HACEDBDI_00301 5.2e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HACEDBDI_00302 2e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HACEDBDI_00304 2.4e-164 S Alpha/beta hydrolase family
HACEDBDI_00305 2.7e-94 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HACEDBDI_00306 2.7e-85 ybfM S SNARE associated Golgi protein
HACEDBDI_00307 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HACEDBDI_00308 4.6e-45 ybfN
HACEDBDI_00309 3.6e-249 S Erythromycin esterase
HACEDBDI_00310 3.9e-192 yceA S Belongs to the UPF0176 family
HACEDBDI_00311 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HACEDBDI_00312 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACEDBDI_00313 9.8e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HACEDBDI_00314 3.2e-127 K UTRA
HACEDBDI_00316 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HACEDBDI_00317 2.8e-260 mmuP E amino acid
HACEDBDI_00318 4.6e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HACEDBDI_00319 2.5e-256 agcS E Sodium alanine symporter
HACEDBDI_00320 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
HACEDBDI_00321 4.7e-228 phoQ 2.7.13.3 T Histidine kinase
HACEDBDI_00322 1.4e-167 glnL T Regulator
HACEDBDI_00323 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HACEDBDI_00324 1.2e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HACEDBDI_00325 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HACEDBDI_00326 5.2e-267 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HACEDBDI_00327 1.5e-124 ycbG K FCD
HACEDBDI_00328 1.9e-294 garD 4.2.1.42, 4.2.1.7 G Altronate
HACEDBDI_00329 2.3e-178 ycbJ S Macrolide 2'-phosphotransferase
HACEDBDI_00330 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HACEDBDI_00331 4.2e-167 eamA1 EG spore germination
HACEDBDI_00332 2.5e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACEDBDI_00333 1.9e-167 T PhoQ Sensor
HACEDBDI_00334 5e-165 ycbN V ABC transporter, ATP-binding protein
HACEDBDI_00335 5.1e-114 S ABC-2 family transporter protein
HACEDBDI_00336 8.2e-53 ycbP S Protein of unknown function (DUF2512)
HACEDBDI_00337 2.2e-78 sleB 3.5.1.28 M Cell wall
HACEDBDI_00338 2.5e-135 ycbR T vWA found in TerF C terminus
HACEDBDI_00339 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HACEDBDI_00340 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HACEDBDI_00341 5.8e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HACEDBDI_00342 6.5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HACEDBDI_00343 2.7e-205 ycbU E Selenocysteine lyase
HACEDBDI_00344 7.9e-226 lmrB EGP the major facilitator superfamily
HACEDBDI_00345 4.8e-102 yxaF K Transcriptional regulator
HACEDBDI_00346 4.9e-61 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HACEDBDI_00347 3.2e-127 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HACEDBDI_00348 8.1e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HACEDBDI_00349 2.3e-55 S RDD family
HACEDBDI_00350 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
HACEDBDI_00351 8.9e-157 2.7.13.3 T GHKL domain
HACEDBDI_00352 1.2e-126 lytR_2 T LytTr DNA-binding domain
HACEDBDI_00353 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HACEDBDI_00354 2.7e-200 natB CP ABC-2 family transporter protein
HACEDBDI_00355 1.7e-22 yccK C Aldo keto reductase
HACEDBDI_00356 1e-142 yccK C Aldo keto reductase
HACEDBDI_00357 6.6e-177 ycdA S Domain of unknown function (DUF5105)
HACEDBDI_00358 9.8e-269 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HACEDBDI_00359 1.9e-259 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HACEDBDI_00360 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
HACEDBDI_00361 2.7e-173 S response regulator aspartate phosphatase
HACEDBDI_00362 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
HACEDBDI_00363 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HACEDBDI_00364 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
HACEDBDI_00365 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HACEDBDI_00366 2.2e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HACEDBDI_00367 1.5e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HACEDBDI_00368 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HACEDBDI_00369 1.1e-104 yceD T proteins involved in stress response, homologs of TerZ and
HACEDBDI_00370 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HACEDBDI_00371 1.4e-136 terC P Protein of unknown function (DUF475)
HACEDBDI_00372 0.0 yceG S Putative component of 'biosynthetic module'
HACEDBDI_00373 2e-192 yceH P Belongs to the TelA family
HACEDBDI_00374 4.3e-217 naiP P Uncharacterised MFS-type transporter YbfB
HACEDBDI_00375 1.2e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
HACEDBDI_00376 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HACEDBDI_00377 5.1e-229 proV 3.6.3.32 E glycine betaine
HACEDBDI_00378 1.3e-127 opuAB P glycine betaine
HACEDBDI_00379 5.3e-164 opuAC E glycine betaine
HACEDBDI_00380 5e-215 amhX S amidohydrolase
HACEDBDI_00381 1.2e-255 ycgA S Membrane
HACEDBDI_00382 4.1e-81 ycgB
HACEDBDI_00383 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HACEDBDI_00384 7.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HACEDBDI_00385 5.2e-290 lctP C L-lactate permease
HACEDBDI_00386 3.6e-261 mdr EGP Major facilitator Superfamily
HACEDBDI_00387 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
HACEDBDI_00388 6.8e-113 ycgF E Lysine exporter protein LysE YggA
HACEDBDI_00389 9.2e-149 yqcI S YqcI/YcgG family
HACEDBDI_00390 1.9e-167 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HACEDBDI_00391 4.8e-73 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HACEDBDI_00392 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HACEDBDI_00393 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HACEDBDI_00394 9.5e-109 tmrB S AAA domain
HACEDBDI_00395 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HACEDBDI_00396 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
HACEDBDI_00397 4.3e-175 oxyR3 K LysR substrate binding domain
HACEDBDI_00398 1.5e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HACEDBDI_00399 2.9e-145 ycgL S Predicted nucleotidyltransferase
HACEDBDI_00400 5.1e-170 ycgM E Proline dehydrogenase
HACEDBDI_00401 3.6e-293 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HACEDBDI_00402 3.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HACEDBDI_00403 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HACEDBDI_00404 2.6e-147 ycgQ S membrane
HACEDBDI_00405 1.2e-139 ycgR S permeases
HACEDBDI_00406 7.2e-158 I alpha/beta hydrolase fold
HACEDBDI_00407 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HACEDBDI_00408 2.7e-282 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HACEDBDI_00409 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HACEDBDI_00410 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HACEDBDI_00411 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HACEDBDI_00412 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HACEDBDI_00413 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
HACEDBDI_00414 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HACEDBDI_00415 3.6e-108 yciB M ErfK YbiS YcfS YnhG
HACEDBDI_00416 5.4e-228 yciC S GTPases (G3E family)
HACEDBDI_00417 1.6e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
HACEDBDI_00418 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HACEDBDI_00420 7.8e-52 yckD S Protein of unknown function (DUF2680)
HACEDBDI_00421 1.6e-38 K MarR family
HACEDBDI_00422 9.3e-24
HACEDBDI_00423 7.8e-121 S AAA domain
HACEDBDI_00424 1.2e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HACEDBDI_00425 1.7e-69 nin S Competence protein J (ComJ)
HACEDBDI_00426 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
HACEDBDI_00427 1e-179 tlpC 2.7.13.3 NT chemotaxis protein
HACEDBDI_00428 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HACEDBDI_00429 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HACEDBDI_00430 1.3e-63 hxlR K transcriptional
HACEDBDI_00431 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACEDBDI_00432 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACEDBDI_00433 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HACEDBDI_00434 5.7e-140 srfAD Q thioesterase
HACEDBDI_00435 4e-226 EGP Major Facilitator Superfamily
HACEDBDI_00436 1.3e-86 S YcxB-like protein
HACEDBDI_00437 5.8e-161 ycxC EG EamA-like transporter family
HACEDBDI_00438 3.3e-250 ycxD K GntR family transcriptional regulator
HACEDBDI_00439 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HACEDBDI_00440 9.7e-115 yczE S membrane
HACEDBDI_00441 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HACEDBDI_00442 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HACEDBDI_00443 6.4e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HACEDBDI_00444 1.2e-160 bsdA K LysR substrate binding domain
HACEDBDI_00445 8.3e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HACEDBDI_00446 1.7e-281 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HACEDBDI_00447 8.9e-39 bsdD 4.1.1.61 S response to toxic substance
HACEDBDI_00448 6.6e-41 yclD
HACEDBDI_00449 6e-157 yclE 3.4.11.5 S Alpha beta hydrolase
HACEDBDI_00450 9.2e-262 dtpT E amino acid peptide transporter
HACEDBDI_00451 5.9e-292 yclG M Pectate lyase superfamily protein
HACEDBDI_00453 1e-277 gerKA EG Spore germination protein
HACEDBDI_00454 4.2e-228 gerKC S spore germination
HACEDBDI_00455 1.9e-198 gerKB F Spore germination protein
HACEDBDI_00456 7.3e-121 yclH P ABC transporter
HACEDBDI_00457 6.2e-202 yclI V ABC transporter (permease) YclI
HACEDBDI_00458 1e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACEDBDI_00459 1.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HACEDBDI_00460 5.2e-71 S aspartate phosphatase
HACEDBDI_00463 5.4e-232 lysC 2.7.2.4 E Belongs to the aspartokinase family
HACEDBDI_00464 7.7e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACEDBDI_00465 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACEDBDI_00466 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HACEDBDI_00467 4.7e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HACEDBDI_00468 3.2e-251 ycnB EGP Major facilitator Superfamily
HACEDBDI_00469 6.5e-154 ycnC K Transcriptional regulator
HACEDBDI_00470 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HACEDBDI_00471 4.7e-45 ycnE S Monooxygenase
HACEDBDI_00472 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HACEDBDI_00473 3.9e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HACEDBDI_00474 6.3e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HACEDBDI_00475 6.4e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HACEDBDI_00476 6.1e-149 glcU U Glucose uptake
HACEDBDI_00477 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACEDBDI_00478 2.9e-100 ycnI S protein conserved in bacteria
HACEDBDI_00479 1.1e-305 ycnJ P protein, homolog of Cu resistance protein CopC
HACEDBDI_00480 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HACEDBDI_00481 2.6e-53
HACEDBDI_00482 4.8e-239 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HACEDBDI_00483 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HACEDBDI_00484 3.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HACEDBDI_00485 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HACEDBDI_00486 1.3e-08 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HACEDBDI_00487 3.2e-74 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HACEDBDI_00488 9.1e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HACEDBDI_00489 3.9e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HACEDBDI_00491 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HACEDBDI_00492 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
HACEDBDI_00493 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HACEDBDI_00494 3.1e-147 ycsI S Belongs to the D-glutamate cyclase family
HACEDBDI_00495 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HACEDBDI_00496 6.2e-185 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HACEDBDI_00497 2.7e-132 kipR K Transcriptional regulator
HACEDBDI_00498 2.9e-119 ycsK E anatomical structure formation involved in morphogenesis
HACEDBDI_00500 1.4e-49 yczJ S biosynthesis
HACEDBDI_00501 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HACEDBDI_00502 7.1e-172 ydhF S Oxidoreductase
HACEDBDI_00503 0.0 mtlR K transcriptional regulator, MtlR
HACEDBDI_00504 2.1e-293 ydaB IQ acyl-CoA ligase
HACEDBDI_00505 5.3e-99 ydaC Q Methyltransferase domain
HACEDBDI_00506 3.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACEDBDI_00507 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HACEDBDI_00508 2.4e-98 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HACEDBDI_00509 7.6e-76 ydaG 1.4.3.5 S general stress protein
HACEDBDI_00510 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HACEDBDI_00511 2.5e-46 ydzA EGP Major facilitator Superfamily
HACEDBDI_00512 2.5e-74 lrpC K Transcriptional regulator
HACEDBDI_00513 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HACEDBDI_00514 2.2e-204 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HACEDBDI_00515 9.4e-150 ydaK T Diguanylate cyclase, GGDEF domain
HACEDBDI_00516 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HACEDBDI_00517 4.5e-233 ydaM M Glycosyl transferase family group 2
HACEDBDI_00518 0.0 ydaN S Bacterial cellulose synthase subunit
HACEDBDI_00519 0.0 ydaO E amino acid
HACEDBDI_00520 6.6e-78 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HACEDBDI_00521 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HACEDBDI_00522 9.4e-40
HACEDBDI_00523 4.3e-223 mntH P H( )-stimulated, divalent metal cation uptake system
HACEDBDI_00525 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HACEDBDI_00526 2.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HACEDBDI_00528 8.9e-59 ydbB G Cupin domain
HACEDBDI_00529 1e-60 ydbC S Domain of unknown function (DUF4937
HACEDBDI_00530 7.9e-154 ydbD P Catalase
HACEDBDI_00531 2.3e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HACEDBDI_00532 8.1e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HACEDBDI_00533 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
HACEDBDI_00534 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HACEDBDI_00535 9.7e-181 ydbI S AI-2E family transporter
HACEDBDI_00536 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
HACEDBDI_00537 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HACEDBDI_00538 2.7e-52 ydbL
HACEDBDI_00539 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HACEDBDI_00540 1.1e-18 S Fur-regulated basic protein B
HACEDBDI_00541 2.2e-07 S Fur-regulated basic protein A
HACEDBDI_00542 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HACEDBDI_00543 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HACEDBDI_00544 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HACEDBDI_00545 1e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HACEDBDI_00546 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HACEDBDI_00547 2.1e-82 ydbS S Bacterial PH domain
HACEDBDI_00548 5.1e-260 ydbT S Membrane
HACEDBDI_00549 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HACEDBDI_00550 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HACEDBDI_00551 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HACEDBDI_00552 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HACEDBDI_00553 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HACEDBDI_00554 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HACEDBDI_00555 1.3e-143 rsbR T Positive regulator of sigma-B
HACEDBDI_00556 5.2e-57 rsbS T antagonist
HACEDBDI_00557 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HACEDBDI_00558 3.5e-188 rsbU 3.1.3.3 KT phosphatase
HACEDBDI_00559 1.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
HACEDBDI_00560 7.8e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HACEDBDI_00561 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACEDBDI_00562 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HACEDBDI_00563 0.0 yhgF K COG2183 Transcriptional accessory protein
HACEDBDI_00564 8.9e-83 ydcK S Belongs to the SprT family
HACEDBDI_00572 3.2e-57 2.3.1.183 M Acetyltransferase (GNAT) domain
HACEDBDI_00573 1.4e-200 O Pyridine nucleotide-disulphide oxidoreductase
HACEDBDI_00574 5.2e-45 arsR K ArsR family transcriptional regulator
HACEDBDI_00575 2.8e-52 arsR K transcriptional
HACEDBDI_00576 3.9e-216 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HACEDBDI_00577 9.2e-74 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HACEDBDI_00578 5e-204 L Belongs to the 'phage' integrase family
HACEDBDI_00579 3.1e-84 immA E IrrE N-terminal-like domain
HACEDBDI_00580 1.4e-60 yvaO K Transcriptional
HACEDBDI_00581 3.1e-16
HACEDBDI_00582 2.7e-39
HACEDBDI_00584 1.7e-63 S Bacterial protein of unknown function (DUF961)
HACEDBDI_00585 6.5e-222 ydcQ D Ftsk spoiiie family protein
HACEDBDI_00586 5.3e-203 nicK L Replication initiation factor
HACEDBDI_00587 4e-16 S Domain of Unknown Function with PDB structure (DUF3850)
HACEDBDI_00589 1.6e-32 yddA
HACEDBDI_00590 1.8e-166 yddB S Conjugative transposon protein TcpC
HACEDBDI_00591 5.1e-40 yddC
HACEDBDI_00592 4.2e-92 yddD S TcpE family
HACEDBDI_00593 0.0 yddE S AAA-like domain
HACEDBDI_00594 1.3e-54 S Domain of unknown function (DUF1874)
HACEDBDI_00595 0.0 yddG S maturation of SSU-rRNA
HACEDBDI_00596 1.5e-186 yddH CBM50 M Lysozyme-like
HACEDBDI_00597 1.8e-84 yddI
HACEDBDI_00598 5.1e-63 S Domain of unknown function with cystatin-like fold (DUF4467)
HACEDBDI_00599 1.2e-73 S response regulator aspartate phosphatase
HACEDBDI_00601 7.9e-74
HACEDBDI_00603 3.2e-114 yecA E amino acid
HACEDBDI_00604 4.6e-107 K Transcriptional regulator
HACEDBDI_00605 2.5e-74 rimJ2 J Acetyltransferase (GNAT) domain
HACEDBDI_00606 1.2e-43
HACEDBDI_00607 5e-142 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HACEDBDI_00608 5.6e-34 K Helix-turn-helix XRE-family like proteins
HACEDBDI_00609 1.9e-40
HACEDBDI_00613 7e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HACEDBDI_00614 8.7e-30 cspL K Cold shock
HACEDBDI_00615 1.2e-77 carD K Transcription factor
HACEDBDI_00616 3.1e-30 ydzE EG spore germination
HACEDBDI_00617 4.9e-162 rhaS5 K AraC-like ligand binding domain
HACEDBDI_00618 2e-172 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HACEDBDI_00619 6.9e-164 ydeE K AraC family transcriptional regulator
HACEDBDI_00620 1.7e-257 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HACEDBDI_00621 2.1e-217 ydeG EGP Major facilitator superfamily
HACEDBDI_00622 2.7e-45 ydeH
HACEDBDI_00623 2.4e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HACEDBDI_00624 3.6e-109
HACEDBDI_00625 1.1e-31 S SNARE associated Golgi protein
HACEDBDI_00626 1.8e-14 ptsH G PTS HPr component phosphorylation site
HACEDBDI_00627 3.4e-84 K Transcriptional regulator C-terminal region
HACEDBDI_00628 2e-152 ydeK EG -transporter
HACEDBDI_00629 8.7e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HACEDBDI_00630 1.3e-72 maoC I N-terminal half of MaoC dehydratase
HACEDBDI_00631 1.8e-104 ydeN S Serine hydrolase
HACEDBDI_00632 5.7e-55 K HxlR-like helix-turn-helix
HACEDBDI_00633 2.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HACEDBDI_00634 8.2e-57 arsR K transcriptional
HACEDBDI_00635 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HACEDBDI_00636 9.8e-146 ydfB J GNAT acetyltransferase
HACEDBDI_00637 2.3e-149 ydfC EG EamA-like transporter family
HACEDBDI_00638 7.4e-272 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HACEDBDI_00639 8.9e-185 gadB 4.1.1.105, 4.1.1.28, 4.1.1.29 E Pyridoxal-dependent decarboxylase conserved domain
HACEDBDI_00640 1.4e-115 ydfE S Flavin reductase like domain
HACEDBDI_00641 3.9e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HACEDBDI_00642 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HACEDBDI_00644 5.2e-175 ydfH 2.7.13.3 T Histidine kinase
HACEDBDI_00645 3.5e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACEDBDI_00646 0.0 ydfJ S drug exporters of the RND superfamily
HACEDBDI_00647 2.9e-173 S Alpha/beta hydrolase family
HACEDBDI_00648 7.2e-116 S Protein of unknown function (DUF554)
HACEDBDI_00649 9.2e-147 K Bacterial transcription activator, effector binding domain
HACEDBDI_00650 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HACEDBDI_00651 2.6e-109 ydfN C nitroreductase
HACEDBDI_00652 2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HACEDBDI_00653 8.8e-63 mhqP S DoxX
HACEDBDI_00654 8.5e-54 traF CO Thioredoxin
HACEDBDI_00655 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HACEDBDI_00656 4.8e-29
HACEDBDI_00658 2.4e-54 ydfR S Protein of unknown function (DUF421)
HACEDBDI_00659 1.4e-30 ydfR S Protein of unknown function (DUF421)
HACEDBDI_00660 5.8e-121 ydfS S Protein of unknown function (DUF421)
HACEDBDI_00661 1.1e-66 cotP O Belongs to the small heat shock protein (HSP20) family
HACEDBDI_00662 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
HACEDBDI_00663 2.7e-34 ydgB S Spore germination protein gerPA/gerPF
HACEDBDI_00664 4.5e-98 K Bacterial regulatory proteins, tetR family
HACEDBDI_00665 1.6e-52 S DoxX-like family
HACEDBDI_00666 4.6e-82 yycN 2.3.1.128 K Acetyltransferase
HACEDBDI_00667 3.2e-303 expZ S ABC transporter
HACEDBDI_00668 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HACEDBDI_00669 4.3e-89 dinB S DinB family
HACEDBDI_00670 2.7e-79 K helix_turn_helix multiple antibiotic resistance protein
HACEDBDI_00671 0.0 ydgH S drug exporters of the RND superfamily
HACEDBDI_00672 1e-113 drgA C nitroreductase
HACEDBDI_00673 2.4e-69 ydgJ K Winged helix DNA-binding domain
HACEDBDI_00674 6.3e-208 tcaB EGP Major facilitator Superfamily
HACEDBDI_00675 4.6e-121 ydhB S membrane transporter protein
HACEDBDI_00676 2.5e-121 ydhC K FCD
HACEDBDI_00677 4.8e-243 ydhD M Glycosyl hydrolase
HACEDBDI_00678 1.9e-225 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HACEDBDI_00679 1.6e-123
HACEDBDI_00680 4.9e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HACEDBDI_00681 6.2e-66 frataxin S Domain of unknown function (DU1801)
HACEDBDI_00683 1.5e-80 K Acetyltransferase (GNAT) domain
HACEDBDI_00684 6.9e-181 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HACEDBDI_00685 2.3e-96 ydhK M Protein of unknown function (DUF1541)
HACEDBDI_00686 6.7e-199 pbuE EGP Major facilitator Superfamily
HACEDBDI_00687 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HACEDBDI_00688 9.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HACEDBDI_00689 2.2e-238 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HACEDBDI_00690 1.4e-280 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HACEDBDI_00691 3.7e-131 ydhQ K UTRA
HACEDBDI_00692 6.8e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HACEDBDI_00693 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
HACEDBDI_00694 2e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HACEDBDI_00695 2.3e-156 ydhU P Catalase
HACEDBDI_00698 3.4e-39 S COG NOG14552 non supervised orthologous group
HACEDBDI_00699 7.8e-08
HACEDBDI_00701 9.3e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HACEDBDI_00702 2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HACEDBDI_00703 3.8e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HACEDBDI_00704 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HACEDBDI_00705 1.1e-184 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HACEDBDI_00706 0.0 ydiF S ABC transporter
HACEDBDI_00707 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HACEDBDI_00708 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HACEDBDI_00709 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HACEDBDI_00710 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HACEDBDI_00711 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HACEDBDI_00712 2.3e-128 ydiL S CAAX protease self-immunity
HACEDBDI_00713 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HACEDBDI_00714 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HACEDBDI_00715 5.8e-151 ydjC S Abhydrolase domain containing 18
HACEDBDI_00716 0.0 K NB-ARC domain
HACEDBDI_00717 8.5e-201 gutB 1.1.1.14 E Dehydrogenase
HACEDBDI_00718 9.9e-250 gutA G MFS/sugar transport protein
HACEDBDI_00719 3.1e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HACEDBDI_00720 1.1e-113 pspA KT Phage shock protein A
HACEDBDI_00721 9.8e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HACEDBDI_00722 1.4e-125 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HACEDBDI_00723 1.3e-147 ydjI S virion core protein (lumpy skin disease virus)
HACEDBDI_00724 8e-196 S Ion transport 2 domain protein
HACEDBDI_00726 7.8e-258 iolT EGP Major facilitator Superfamily
HACEDBDI_00727 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HACEDBDI_00728 4.5e-64 ydjM M Lytic transglycolase
HACEDBDI_00729 1.6e-151 ydjN U Involved in the tonB-independent uptake of proteins
HACEDBDI_00731 1.4e-34 ydjO S Cold-inducible protein YdjO
HACEDBDI_00732 8.4e-156 ydjP I Alpha/beta hydrolase family
HACEDBDI_00733 3.3e-175 yeaA S Protein of unknown function (DUF4003)
HACEDBDI_00734 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HACEDBDI_00735 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HACEDBDI_00736 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HACEDBDI_00737 1.5e-175 yeaC S COG0714 MoxR-like ATPases
HACEDBDI_00738 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HACEDBDI_00739 0.0 yebA E COG1305 Transglutaminase-like enzymes
HACEDBDI_00740 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HACEDBDI_00741 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
HACEDBDI_00742 6e-245 S Domain of unknown function (DUF4179)
HACEDBDI_00743 1.5e-210 pbuG S permease
HACEDBDI_00744 8.3e-116 yebC M Membrane
HACEDBDI_00746 8.9e-93 yebE S UPF0316 protein
HACEDBDI_00747 8e-28 yebG S NETI protein
HACEDBDI_00748 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HACEDBDI_00749 1.3e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HACEDBDI_00750 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HACEDBDI_00751 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HACEDBDI_00752 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HACEDBDI_00753 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HACEDBDI_00754 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HACEDBDI_00755 4.7e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HACEDBDI_00756 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HACEDBDI_00757 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HACEDBDI_00758 2.1e-285 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HACEDBDI_00759 2.9e-232 purD 6.3.4.13 F Belongs to the GARS family
HACEDBDI_00760 1e-72 K helix_turn_helix ASNC type
HACEDBDI_00761 3e-229 yjeH E Amino acid permease
HACEDBDI_00762 2.7e-27 S Protein of unknown function (DUF2892)
HACEDBDI_00763 0.0 yerA 3.5.4.2 F adenine deaminase
HACEDBDI_00764 2.2e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
HACEDBDI_00765 4.8e-51 yerC S protein conserved in bacteria
HACEDBDI_00766 2.2e-301 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HACEDBDI_00768 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HACEDBDI_00769 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HACEDBDI_00770 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HACEDBDI_00771 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
HACEDBDI_00772 6.6e-195 yerI S homoserine kinase type II (protein kinase fold)
HACEDBDI_00773 1.6e-123 sapB S MgtC SapB transporter
HACEDBDI_00774 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HACEDBDI_00775 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HACEDBDI_00776 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HACEDBDI_00777 8.9e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HACEDBDI_00778 3.4e-144 yerO K Transcriptional regulator
HACEDBDI_00779 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HACEDBDI_00780 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HACEDBDI_00781 1.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HACEDBDI_00782 2.8e-258 L Recombinase
HACEDBDI_00784 1.2e-33
HACEDBDI_00785 1.8e-99 S Putative inner membrane protein (DUF1819)
HACEDBDI_00786 1.8e-101 S Domain of unknown function (DUF1788)
HACEDBDI_00787 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
HACEDBDI_00788 0.0 V restriction
HACEDBDI_00789 2.5e-18
HACEDBDI_00790 0.0 S PglZ domain
HACEDBDI_00791 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
HACEDBDI_00793 1.2e-13 K Helix-turn-helix domain
HACEDBDI_00794 1.9e-26 S Psort location Cytoplasmic, score 8.87
HACEDBDI_00795 2.5e-75 S Psort location Cytoplasmic, score 8.87
HACEDBDI_00798 3.2e-20
HACEDBDI_00799 3e-97 L Reverse transcriptase (RNA-dependent DNA polymerase)
HACEDBDI_00801 0.0 L AAA domain
HACEDBDI_00802 1.1e-41 S Protein of unknown function, DUF600
HACEDBDI_00803 1.5e-12 S Protein of unknown function, DUF600
HACEDBDI_00804 1.7e-55 S Protein of unknown function, DUF600
HACEDBDI_00805 4.6e-79 S Protein of unknown function, DUF600
HACEDBDI_00806 3.4e-56 S Protein of unknown function, DUF600
HACEDBDI_00807 0.0 L nucleic acid phosphodiester bond hydrolysis
HACEDBDI_00808 4.9e-174 3.4.24.40 CO amine dehydrogenase activity
HACEDBDI_00809 3e-39
HACEDBDI_00810 4.1e-209 S Tetratricopeptide repeat
HACEDBDI_00812 2.7e-126 yeeN K transcriptional regulatory protein
HACEDBDI_00814 2e-98 dhaR3 K Transcriptional regulator
HACEDBDI_00815 9.7e-82 yesE S SnoaL-like domain
HACEDBDI_00816 1.1e-145 yesF GM NAD(P)H-binding
HACEDBDI_00817 1.5e-44 cotJA S Spore coat associated protein JA (CotJA)
HACEDBDI_00818 5.6e-45 cotJB S CotJB protein
HACEDBDI_00819 5.2e-104 cotJC P Spore Coat
HACEDBDI_00820 6e-102 yesJ K Acetyltransferase (GNAT) family
HACEDBDI_00822 1.2e-101 yesL S Protein of unknown function, DUF624
HACEDBDI_00823 0.0 yesM 2.7.13.3 T Histidine kinase
HACEDBDI_00824 1.4e-201 yesN K helix_turn_helix, arabinose operon control protein
HACEDBDI_00825 2.3e-245 yesO G Bacterial extracellular solute-binding protein
HACEDBDI_00826 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
HACEDBDI_00827 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
HACEDBDI_00828 2.3e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HACEDBDI_00829 0.0 yesS K Transcriptional regulator
HACEDBDI_00830 7.9e-131 E GDSL-like Lipase/Acylhydrolase
HACEDBDI_00831 5.1e-127 yesU S Domain of unknown function (DUF1961)
HACEDBDI_00832 1.5e-112 yesV S Protein of unknown function, DUF624
HACEDBDI_00833 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HACEDBDI_00834 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HACEDBDI_00835 1.3e-122 yesY E GDSL-like Lipase/Acylhydrolase
HACEDBDI_00836 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HACEDBDI_00837 0.0 yetA
HACEDBDI_00838 8.4e-287 lplA G Bacterial extracellular solute-binding protein
HACEDBDI_00839 9.4e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HACEDBDI_00840 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HACEDBDI_00841 1.7e-251 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HACEDBDI_00842 5.2e-122 yetF S membrane
HACEDBDI_00843 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HACEDBDI_00844 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HACEDBDI_00845 9.2e-34
HACEDBDI_00846 7.1e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HACEDBDI_00847 5.8e-19 yezD S Uncharacterized small protein (DUF2292)
HACEDBDI_00848 5.3e-105 yetJ S Belongs to the BI1 family
HACEDBDI_00849 1.2e-153 yetK EG EamA-like transporter family
HACEDBDI_00850 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
HACEDBDI_00851 1.2e-208 yetM CH FAD binding domain
HACEDBDI_00852 1.8e-198 yetN S Protein of unknown function (DUF3900)
HACEDBDI_00853 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HACEDBDI_00854 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HACEDBDI_00855 3.3e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
HACEDBDI_00856 3.2e-172 yfnG 4.2.1.45 M dehydratase
HACEDBDI_00857 4.3e-177 yfnF M Nucleotide-diphospho-sugar transferase
HACEDBDI_00858 2.7e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HACEDBDI_00859 1.5e-188 yfnD M Nucleotide-diphospho-sugar transferase
HACEDBDI_00860 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
HACEDBDI_00861 3.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HACEDBDI_00862 7.9e-239 yfnA E amino acid
HACEDBDI_00863 3.1e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HACEDBDI_00864 1.1e-113 yfmS NT chemotaxis protein
HACEDBDI_00865 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HACEDBDI_00866 2.8e-73 yfmQ S Uncharacterised protein from bacillus cereus group
HACEDBDI_00867 1.4e-69 yfmP K transcriptional
HACEDBDI_00868 6.2e-208 yfmO EGP Major facilitator Superfamily
HACEDBDI_00869 1.6e-59 isp O Subtilase family
HACEDBDI_00870 6.4e-19
HACEDBDI_00872 6.3e-57
HACEDBDI_00873 3.5e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HACEDBDI_00874 4.5e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HACEDBDI_00875 6.8e-75 yfmK 2.3.1.128 K acetyltransferase
HACEDBDI_00876 1.5e-186 yfmJ S N-terminal domain of oxidoreductase
HACEDBDI_00877 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HACEDBDI_00878 1.4e-168 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACEDBDI_00879 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACEDBDI_00880 7.7e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HACEDBDI_00881 2.9e-24 S Protein of unknown function (DUF3212)
HACEDBDI_00882 2.2e-57 yflT S Heat induced stress protein YflT
HACEDBDI_00883 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HACEDBDI_00884 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
HACEDBDI_00885 1.5e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HACEDBDI_00886 2.2e-117 citT T response regulator
HACEDBDI_00887 1.4e-178 yflP S Tripartite tricarboxylate transporter family receptor
HACEDBDI_00888 8.5e-227 citM C Citrate transporter
HACEDBDI_00889 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HACEDBDI_00890 1.3e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HACEDBDI_00891 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HACEDBDI_00892 6.4e-122 yflK S protein conserved in bacteria
HACEDBDI_00893 8.9e-18 yflJ S Protein of unknown function (DUF2639)
HACEDBDI_00894 4.1e-19 yflI
HACEDBDI_00895 9.1e-50 yflH S Protein of unknown function (DUF3243)
HACEDBDI_00896 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HACEDBDI_00897 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HACEDBDI_00898 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HACEDBDI_00899 6e-67 yhdN S Domain of unknown function (DUF1992)
HACEDBDI_00900 2.8e-252 agcS_1 E Sodium alanine symporter
HACEDBDI_00901 8.6e-193 E Spore germination protein
HACEDBDI_00903 2.5e-206 yfkR S spore germination
HACEDBDI_00904 5.8e-283 yfkQ EG Spore germination protein
HACEDBDI_00905 4e-254 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACEDBDI_00906 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HACEDBDI_00907 1.8e-133 treR K transcriptional
HACEDBDI_00908 1.1e-124 yfkO C nitroreductase
HACEDBDI_00909 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HACEDBDI_00910 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
HACEDBDI_00911 6.8e-207 ydiM EGP Major facilitator Superfamily
HACEDBDI_00912 1.3e-28 yfkK S Belongs to the UPF0435 family
HACEDBDI_00913 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HACEDBDI_00914 2.4e-50 yfkI S gas vesicle protein
HACEDBDI_00915 9.7e-144 yihY S Belongs to the UPF0761 family
HACEDBDI_00916 5e-08
HACEDBDI_00917 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HACEDBDI_00918 1.8e-182 cax P COG0387 Ca2 H antiporter
HACEDBDI_00919 3.8e-145 yfkD S YfkD-like protein
HACEDBDI_00920 6e-149 yfkC M Mechanosensitive ion channel
HACEDBDI_00921 5.4e-222 yfkA S YfkB-like domain
HACEDBDI_00922 1.1e-26 yfjT
HACEDBDI_00923 2.6e-154 pdaA G deacetylase
HACEDBDI_00924 3.4e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HACEDBDI_00925 1.7e-184 corA P Mediates influx of magnesium ions
HACEDBDI_00926 2.2e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HACEDBDI_00927 1.2e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HACEDBDI_00928 3.9e-44 S YfzA-like protein
HACEDBDI_00929 6.9e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HACEDBDI_00930 7.3e-85 yfjM S Psort location Cytoplasmic, score
HACEDBDI_00931 1.3e-27 yfjL
HACEDBDI_00932 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HACEDBDI_00933 2.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HACEDBDI_00934 6.7e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HACEDBDI_00935 3.1e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HACEDBDI_00936 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HACEDBDI_00937 5.8e-25 sspH S Belongs to the SspH family
HACEDBDI_00938 8.9e-56 yfjF S UPF0060 membrane protein
HACEDBDI_00939 9.4e-79 S Family of unknown function (DUF5381)
HACEDBDI_00940 1.8e-101 yfjD S Family of unknown function (DUF5381)
HACEDBDI_00941 4.1e-144 yfjC
HACEDBDI_00942 9.2e-191 yfjB
HACEDBDI_00943 1.1e-44 yfjA S Belongs to the WXG100 family
HACEDBDI_00944 1.1e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HACEDBDI_00945 1e-139 glvR K Helix-turn-helix domain, rpiR family
HACEDBDI_00946 5.2e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACEDBDI_00947 0.0 yobO M COG5434 Endopolygalacturonase
HACEDBDI_00948 4.9e-307 yfiB3 V ABC transporter
HACEDBDI_00949 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HACEDBDI_00950 9.8e-65 mhqP S DoxX
HACEDBDI_00951 5.3e-161 yfiE 1.13.11.2 S glyoxalase
HACEDBDI_00952 3.4e-187 yxjM T Histidine kinase
HACEDBDI_00953 2.8e-109 KT LuxR family transcriptional regulator
HACEDBDI_00954 1.2e-166 V ABC transporter, ATP-binding protein
HACEDBDI_00955 2.3e-207 V ABC-2 family transporter protein
HACEDBDI_00956 9e-204 V COG0842 ABC-type multidrug transport system, permease component
HACEDBDI_00957 8.3e-99 padR K transcriptional
HACEDBDI_00958 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HACEDBDI_00959 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HACEDBDI_00960 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
HACEDBDI_00961 5.9e-283 yfiU EGP Major facilitator Superfamily
HACEDBDI_00962 4.9e-79 yfiV K transcriptional
HACEDBDI_00963 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HACEDBDI_00964 8.2e-174 yfiY P ABC transporter substrate-binding protein
HACEDBDI_00965 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACEDBDI_00966 8.9e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACEDBDI_00967 5.1e-167 yfhB 5.3.3.17 S PhzF family
HACEDBDI_00968 3.9e-107 yfhC C nitroreductase
HACEDBDI_00969 2.1e-25 yfhD S YfhD-like protein
HACEDBDI_00971 1.2e-171 yfhF S nucleoside-diphosphate sugar epimerase
HACEDBDI_00972 4.3e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HACEDBDI_00973 3.7e-51 yfhH S Protein of unknown function (DUF1811)
HACEDBDI_00975 1.1e-209 yfhI EGP Major facilitator Superfamily
HACEDBDI_00976 6.2e-20 sspK S reproduction
HACEDBDI_00977 1.3e-44 yfhJ S WVELL protein
HACEDBDI_00978 2.4e-87 batE T Bacterial SH3 domain homologues
HACEDBDI_00979 3.9e-50 yfhL S SdpI/YhfL protein family
HACEDBDI_00980 8.2e-170 yfhM S Alpha beta hydrolase
HACEDBDI_00981 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HACEDBDI_00982 0.0 yfhO S Bacterial membrane protein YfhO
HACEDBDI_00983 1.2e-185 yfhP S membrane-bound metal-dependent
HACEDBDI_00984 3.3e-210 mutY L A G-specific
HACEDBDI_00985 6.9e-36 yfhS
HACEDBDI_00986 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACEDBDI_00987 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HACEDBDI_00988 3.3e-37 ygaB S YgaB-like protein
HACEDBDI_00989 1.3e-104 ygaC J Belongs to the UPF0374 family
HACEDBDI_00990 3.1e-301 ygaD V ABC transporter
HACEDBDI_00991 8.7e-180 ygaE S Membrane
HACEDBDI_00992 8.9e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HACEDBDI_00993 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
HACEDBDI_00994 4e-80 perR P Belongs to the Fur family
HACEDBDI_00995 2.8e-55 ygzB S UPF0295 protein
HACEDBDI_00996 6.7e-167 ygxA S Nucleotidyltransferase-like
HACEDBDI_00997 3.4e-39 S COG NOG14552 non supervised orthologous group
HACEDBDI_01002 7.8e-08
HACEDBDI_01010 2e-08
HACEDBDI_01014 5e-142 spo0M S COG4326 Sporulation control protein
HACEDBDI_01015 1.2e-26
HACEDBDI_01016 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HACEDBDI_01017 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HACEDBDI_01019 3.5e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HACEDBDI_01020 3e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HACEDBDI_01021 1.5e-170 ssuA M Sulfonate ABC transporter
HACEDBDI_01022 1.9e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HACEDBDI_01023 2e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HACEDBDI_01025 5e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HACEDBDI_01026 5.5e-75 ygaO
HACEDBDI_01027 4.4e-29 K Transcriptional regulator
HACEDBDI_01029 2.5e-112 yhzB S B3/4 domain
HACEDBDI_01030 6e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HACEDBDI_01031 1.7e-176 yhbB S Putative amidase domain
HACEDBDI_01032 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HACEDBDI_01033 3.5e-109 yhbD K Protein of unknown function (DUF4004)
HACEDBDI_01034 9.2e-58 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HACEDBDI_01035 2.7e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HACEDBDI_01036 0.0 prkA T Ser protein kinase
HACEDBDI_01037 2.5e-225 yhbH S Belongs to the UPF0229 family
HACEDBDI_01038 2.2e-76 yhbI K DNA-binding transcription factor activity
HACEDBDI_01039 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HACEDBDI_01040 3.1e-271 yhcA EGP Major facilitator Superfamily
HACEDBDI_01041 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HACEDBDI_01042 2.8e-37 yhcC
HACEDBDI_01043 7.8e-55
HACEDBDI_01044 6.6e-60 yhcF K Transcriptional regulator
HACEDBDI_01045 1.7e-120 yhcG V ABC transporter, ATP-binding protein
HACEDBDI_01046 8.5e-165 yhcH V ABC transporter, ATP-binding protein
HACEDBDI_01047 1.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HACEDBDI_01048 1e-30 cspB K Cold-shock protein
HACEDBDI_01049 9.1e-150 metQ M Belongs to the nlpA lipoprotein family
HACEDBDI_01050 1.5e-150 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HACEDBDI_01051 1.8e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HACEDBDI_01052 8.3e-78 S Protein of unknown function (DUF2812)
HACEDBDI_01053 2.3e-48 K Transcriptional regulator PadR-like family
HACEDBDI_01054 1.3e-38 yhcM
HACEDBDI_01055 2.2e-65 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HACEDBDI_01056 1.4e-165 yhcP
HACEDBDI_01057 5.2e-100 yhcQ M Spore coat protein
HACEDBDI_01058 1.6e-272 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HACEDBDI_01059 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HACEDBDI_01060 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HACEDBDI_01061 5.1e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HACEDBDI_01062 2.1e-67 yhcU S Family of unknown function (DUF5365)
HACEDBDI_01063 9.9e-68 yhcV S COG0517 FOG CBS domain
HACEDBDI_01064 1.3e-119 yhcW 5.4.2.6 S hydrolase
HACEDBDI_01065 1.7e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HACEDBDI_01066 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HACEDBDI_01067 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HACEDBDI_01068 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HACEDBDI_01069 3e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HACEDBDI_01070 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HACEDBDI_01071 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HACEDBDI_01072 2e-211 yhcY 2.7.13.3 T Histidine kinase
HACEDBDI_01073 7.2e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACEDBDI_01074 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
HACEDBDI_01075 1.2e-38 yhdB S YhdB-like protein
HACEDBDI_01076 4.8e-54 yhdC S Protein of unknown function (DUF3889)
HACEDBDI_01077 1.2e-184 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HACEDBDI_01078 6e-76 nsrR K Transcriptional regulator
HACEDBDI_01079 1.3e-237 ygxB M Conserved TM helix
HACEDBDI_01080 4.8e-276 ycgB S Stage V sporulation protein R
HACEDBDI_01081 2.2e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HACEDBDI_01082 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HACEDBDI_01083 3.8e-162 citR K Transcriptional regulator
HACEDBDI_01084 2.9e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
HACEDBDI_01085 7.8e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACEDBDI_01086 1e-249 yhdG E amino acid
HACEDBDI_01087 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HACEDBDI_01088 3.2e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HACEDBDI_01089 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HACEDBDI_01090 8.1e-45 yhdK S Sigma-M inhibitor protein
HACEDBDI_01091 6.6e-201 yhdL S Sigma factor regulator N-terminal
HACEDBDI_01092 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HACEDBDI_01093 1.5e-191 yhdN C Aldo keto reductase
HACEDBDI_01094 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HACEDBDI_01095 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HACEDBDI_01096 4.1e-74 cueR K transcriptional
HACEDBDI_01097 4.4e-222 yhdR 2.6.1.1 E Aminotransferase
HACEDBDI_01098 9.6e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HACEDBDI_01099 3.2e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HACEDBDI_01100 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HACEDBDI_01101 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HACEDBDI_01103 8.4e-183 yhdY M Mechanosensitive ion channel
HACEDBDI_01104 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HACEDBDI_01105 1.9e-147 yheN G deacetylase
HACEDBDI_01106 4e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HACEDBDI_01107 1.7e-225 nhaC C Na H antiporter
HACEDBDI_01108 1.5e-83 nhaX T Belongs to the universal stress protein A family
HACEDBDI_01109 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HACEDBDI_01110 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HACEDBDI_01111 3.8e-108 yheG GM NAD(P)H-binding
HACEDBDI_01112 6.3e-28 sspB S spore protein
HACEDBDI_01113 1.3e-36 yheE S Family of unknown function (DUF5342)
HACEDBDI_01114 1.1e-264 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HACEDBDI_01115 4.3e-216 yheC HJ YheC/D like ATP-grasp
HACEDBDI_01116 2.2e-202 yheB S Belongs to the UPF0754 family
HACEDBDI_01117 9.5e-48 yheA S Belongs to the UPF0342 family
HACEDBDI_01118 2.9e-204 yhaZ L DNA alkylation repair enzyme
HACEDBDI_01119 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HACEDBDI_01120 1.8e-292 hemZ H coproporphyrinogen III oxidase
HACEDBDI_01121 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HACEDBDI_01122 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HACEDBDI_01124 4.2e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
HACEDBDI_01125 2.4e-26 S YhzD-like protein
HACEDBDI_01126 2.6e-166 yhaQ S ABC transporter, ATP-binding protein
HACEDBDI_01127 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HACEDBDI_01128 1.3e-224 yhaO L DNA repair exonuclease
HACEDBDI_01129 0.0 yhaN L AAA domain
HACEDBDI_01130 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HACEDBDI_01131 1.6e-21 yhaL S Sporulation protein YhaL
HACEDBDI_01132 3.2e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HACEDBDI_01133 8.7e-90 yhaK S Putative zincin peptidase
HACEDBDI_01134 2.2e-54 yhaI S Protein of unknown function (DUF1878)
HACEDBDI_01135 1e-113 hpr K Negative regulator of protease production and sporulation
HACEDBDI_01136 8.2e-39 yhaH S YtxH-like protein
HACEDBDI_01137 5.4e-21
HACEDBDI_01138 3.6e-80 trpP S Tryptophan transporter TrpP
HACEDBDI_01139 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HACEDBDI_01140 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HACEDBDI_01141 2.3e-136 ecsA V transporter (ATP-binding protein)
HACEDBDI_01142 1.8e-215 ecsB U ABC transporter
HACEDBDI_01143 1.2e-113 ecsC S EcsC protein family
HACEDBDI_01144 5.4e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HACEDBDI_01145 1.7e-241 yhfA C membrane
HACEDBDI_01146 1.6e-33 1.15.1.2 C Rubrerythrin
HACEDBDI_01147 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HACEDBDI_01148 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HACEDBDI_01149 1.2e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HACEDBDI_01150 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HACEDBDI_01151 7.7e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HACEDBDI_01152 5.4e-101 yhgD K Transcriptional regulator
HACEDBDI_01153 3e-214 yhgE S YhgE Pip N-terminal domain protein
HACEDBDI_01154 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HACEDBDI_01155 3.5e-135 yhfC S Putative membrane peptidase family (DUF2324)
HACEDBDI_01156 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HACEDBDI_01157 9.2e-71 3.4.13.21 S ASCH
HACEDBDI_01158 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HACEDBDI_01159 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HACEDBDI_01160 6.3e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
HACEDBDI_01161 5e-111 yhfK GM NmrA-like family
HACEDBDI_01162 1.2e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HACEDBDI_01163 1.3e-64 yhfM
HACEDBDI_01164 1e-240 yhfN 3.4.24.84 O Peptidase M48
HACEDBDI_01165 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HACEDBDI_01166 4.3e-77 VY92_01935 K acetyltransferase
HACEDBDI_01167 3.1e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
HACEDBDI_01168 9e-157 yfmC M Periplasmic binding protein
HACEDBDI_01169 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HACEDBDI_01170 2.9e-196 vraB 2.3.1.9 I Belongs to the thiolase family
HACEDBDI_01171 8.4e-276 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HACEDBDI_01172 5e-91 bioY S BioY family
HACEDBDI_01173 1.7e-182 hemAT NT chemotaxis protein
HACEDBDI_01174 4.7e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HACEDBDI_01175 4.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACEDBDI_01176 1.3e-32 yhzC S IDEAL
HACEDBDI_01177 4.2e-109 comK K Competence transcription factor
HACEDBDI_01178 6.2e-168 IQ Enoyl-(Acyl carrier protein) reductase
HACEDBDI_01179 3.9e-41 yhjA S Excalibur calcium-binding domain
HACEDBDI_01180 1.4e-262 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HACEDBDI_01181 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HACEDBDI_01182 6.7e-60 yhjD
HACEDBDI_01183 9.1e-110 yhjE S SNARE associated Golgi protein
HACEDBDI_01184 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HACEDBDI_01185 1.3e-282 yhjG CH FAD binding domain
HACEDBDI_01186 1.2e-91 yhjH K helix_turn_helix multiple antibiotic resistance protein
HACEDBDI_01189 1.9e-212 glcP G Major Facilitator Superfamily
HACEDBDI_01190 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HACEDBDI_01191 4.9e-159 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HACEDBDI_01192 5.4e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HACEDBDI_01193 6.5e-187 yhjM 5.1.1.1 K Transcriptional regulator
HACEDBDI_01194 4.2e-201 abrB S membrane
HACEDBDI_01195 7.4e-209 EGP Transmembrane secretion effector
HACEDBDI_01196 0.0 S Sugar transport-related sRNA regulator N-term
HACEDBDI_01197 2.2e-78 yhjR S Rubrerythrin
HACEDBDI_01198 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HACEDBDI_01199 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HACEDBDI_01200 2.6e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HACEDBDI_01201 0.0 sbcC L COG0419 ATPase involved in DNA repair
HACEDBDI_01202 2.1e-48 yisB V COG1403 Restriction endonuclease
HACEDBDI_01203 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HACEDBDI_01204 5.3e-63 gerPE S Spore germination protein GerPE
HACEDBDI_01205 3.1e-23 gerPD S Spore germination protein
HACEDBDI_01206 5.3e-54 gerPC S Spore germination protein
HACEDBDI_01207 4e-34 gerPB S cell differentiation
HACEDBDI_01208 1.9e-33 gerPA S Spore germination protein
HACEDBDI_01209 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HACEDBDI_01210 2.9e-173 cotH M Spore Coat
HACEDBDI_01211 2.1e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HACEDBDI_01212 3.9e-57 yisL S UPF0344 protein
HACEDBDI_01213 0.0 wprA O Belongs to the peptidase S8 family
HACEDBDI_01214 1.5e-100 yisN S Protein of unknown function (DUF2777)
HACEDBDI_01215 0.0 asnO 6.3.5.4 E Asparagine synthase
HACEDBDI_01216 4.7e-88 yizA S Damage-inducible protein DinB
HACEDBDI_01217 1e-145 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HACEDBDI_01218 1.5e-242 yisQ V Mate efflux family protein
HACEDBDI_01219 4.5e-160 yisR K Transcriptional regulator
HACEDBDI_01220 6.9e-184 purR K helix_turn _helix lactose operon repressor
HACEDBDI_01221 1.6e-191 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HACEDBDI_01222 7e-92 yisT S DinB family
HACEDBDI_01223 6e-106 argO S Lysine exporter protein LysE YggA
HACEDBDI_01224 1.8e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HACEDBDI_01225 7.5e-35 mcbG S Pentapeptide repeats (9 copies)
HACEDBDI_01226 1.2e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HACEDBDI_01227 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HACEDBDI_01228 1.9e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HACEDBDI_01229 2.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HACEDBDI_01230 7.6e-118 comB 3.1.3.71 H Belongs to the ComB family
HACEDBDI_01231 1.6e-140 yitD 4.4.1.19 S synthase
HACEDBDI_01232 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HACEDBDI_01233 3.5e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HACEDBDI_01234 2.6e-228 yitG EGP Major facilitator Superfamily
HACEDBDI_01235 8.7e-148 yitH K Acetyltransferase (GNAT) domain
HACEDBDI_01236 3e-70 yjcF S Acetyltransferase (GNAT) domain
HACEDBDI_01237 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HACEDBDI_01238 4.3e-54 yajQ S Belongs to the UPF0234 family
HACEDBDI_01239 3.4e-160 cvfB S protein conserved in bacteria
HACEDBDI_01240 8.5e-94
HACEDBDI_01241 2.6e-169
HACEDBDI_01242 5.8e-97 S Sporulation delaying protein SdpA
HACEDBDI_01243 1.5e-58 K Transcriptional regulator PadR-like family
HACEDBDI_01244 8e-92
HACEDBDI_01245 1.4e-44 yitR S Domain of unknown function (DUF3784)
HACEDBDI_01246 1.1e-308 nprB 3.4.24.28 E Peptidase M4
HACEDBDI_01247 2.5e-158 yitS S protein conserved in bacteria
HACEDBDI_01248 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HACEDBDI_01249 5e-73 ipi S Intracellular proteinase inhibitor
HACEDBDI_01250 1.2e-17 S Protein of unknown function (DUF3813)
HACEDBDI_01252 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HACEDBDI_01253 3.8e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HACEDBDI_01254 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HACEDBDI_01255 1.5e-22 pilT S Proteolipid membrane potential modulator
HACEDBDI_01256 3.7e-268 yitY C D-arabinono-1,4-lactone oxidase
HACEDBDI_01257 1.7e-88 norB G Major Facilitator Superfamily
HACEDBDI_01258 5.6e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HACEDBDI_01259 5.9e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HACEDBDI_01260 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HACEDBDI_01261 1.1e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HACEDBDI_01262 4.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HACEDBDI_01263 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HACEDBDI_01264 3.6e-174 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HACEDBDI_01265 9.5e-28 yjzC S YjzC-like protein
HACEDBDI_01266 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HACEDBDI_01267 1.1e-141 yjaU I carboxylic ester hydrolase activity
HACEDBDI_01268 5.8e-100 yjaV
HACEDBDI_01269 2.5e-183 med S Transcriptional activator protein med
HACEDBDI_01270 2.8e-25 comZ S ComZ
HACEDBDI_01272 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HACEDBDI_01273 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HACEDBDI_01274 2.5e-149 yjaZ O Zn-dependent protease
HACEDBDI_01275 3.9e-184 appD P Belongs to the ABC transporter superfamily
HACEDBDI_01276 2.7e-185 appF E Belongs to the ABC transporter superfamily
HACEDBDI_01277 5.5e-276 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HACEDBDI_01278 8.5e-168 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HACEDBDI_01279 3.6e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HACEDBDI_01280 5e-147 yjbA S Belongs to the UPF0736 family
HACEDBDI_01281 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HACEDBDI_01282 8e-307 oppA E ABC transporter substrate-binding protein
HACEDBDI_01283 8.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HACEDBDI_01284 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HACEDBDI_01285 6.8e-198 oppD P Belongs to the ABC transporter superfamily
HACEDBDI_01286 1.2e-171 oppF E Belongs to the ABC transporter superfamily
HACEDBDI_01287 2e-203 yjbB EGP Major Facilitator Superfamily
HACEDBDI_01288 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HACEDBDI_01289 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HACEDBDI_01290 1.3e-111 yjbE P Integral membrane protein TerC family
HACEDBDI_01291 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HACEDBDI_01292 3.4e-219 yjbF S Competence protein
HACEDBDI_01293 0.0 pepF E oligoendopeptidase F
HACEDBDI_01294 1.8e-20
HACEDBDI_01295 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HACEDBDI_01296 3.7e-72 yjbI S Bacterial-like globin
HACEDBDI_01297 1.3e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HACEDBDI_01298 7.1e-101 yjbK S protein conserved in bacteria
HACEDBDI_01299 2.1e-61 yjbL S Belongs to the UPF0738 family
HACEDBDI_01300 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HACEDBDI_01301 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HACEDBDI_01302 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HACEDBDI_01303 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HACEDBDI_01304 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HACEDBDI_01305 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HACEDBDI_01306 4.9e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HACEDBDI_01307 8.8e-217 thiO 1.4.3.19 E Glycine oxidase
HACEDBDI_01308 2.6e-29 thiS H thiamine diphosphate biosynthetic process
HACEDBDI_01309 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HACEDBDI_01310 1.5e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HACEDBDI_01311 7.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HACEDBDI_01312 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HACEDBDI_01313 5.9e-54 yjbX S Spore coat protein
HACEDBDI_01314 5.2e-83 cotZ S Spore coat protein
HACEDBDI_01315 3.4e-96 cotY S Spore coat protein Z
HACEDBDI_01316 1.4e-38 cotX S Spore Coat Protein X and V domain
HACEDBDI_01317 1.4e-10 cotW
HACEDBDI_01318 1.4e-23 cotV S Spore Coat Protein X and V domain
HACEDBDI_01319 1.9e-56 yjcA S Protein of unknown function (DUF1360)
HACEDBDI_01322 4.9e-38 spoVIF S Stage VI sporulation protein F
HACEDBDI_01323 0.0 yjcD 3.6.4.12 L DNA helicase
HACEDBDI_01324 1.7e-38
HACEDBDI_01325 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HACEDBDI_01326 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HACEDBDI_01327 2.9e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
HACEDBDI_01328 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HACEDBDI_01329 8.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HACEDBDI_01330 1e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
HACEDBDI_01331 6e-211 yjcL S Protein of unknown function (DUF819)
HACEDBDI_01333 5.2e-18
HACEDBDI_01334 4.6e-38
HACEDBDI_01335 1e-29
HACEDBDI_01336 1.5e-237 M nucleic acid phosphodiester bond hydrolysis
HACEDBDI_01337 4.3e-70
HACEDBDI_01338 7.3e-16
HACEDBDI_01339 1.5e-49
HACEDBDI_01340 3.7e-21 S YolD-like protein
HACEDBDI_01343 2.4e-33 yjcS S Antibiotic biosynthesis monooxygenase
HACEDBDI_01345 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HACEDBDI_01346 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HACEDBDI_01347 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HACEDBDI_01348 4.1e-50 yjdF S Protein of unknown function (DUF2992)
HACEDBDI_01349 2.2e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HACEDBDI_01351 1.2e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HACEDBDI_01352 1.6e-28 S Domain of unknown function (DUF4177)
HACEDBDI_01353 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
HACEDBDI_01354 2.3e-69 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HACEDBDI_01355 1.4e-90 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HACEDBDI_01357 1.4e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
HACEDBDI_01358 5.5e-83 S Protein of unknown function (DUF2690)
HACEDBDI_01359 3.6e-21 yjfB S Putative motility protein
HACEDBDI_01360 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
HACEDBDI_01361 1.2e-45 T PhoQ Sensor
HACEDBDI_01362 8.9e-104 yjgB S Domain of unknown function (DUF4309)
HACEDBDI_01363 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HACEDBDI_01364 4.3e-95 yjgD S Protein of unknown function (DUF1641)
HACEDBDI_01365 8.7e-07 S Domain of unknown function (DUF4352)
HACEDBDI_01366 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HACEDBDI_01368 1.9e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HACEDBDI_01369 7.7e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HACEDBDI_01370 1.4e-29
HACEDBDI_01371 6.6e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HACEDBDI_01372 1.9e-122 ybbM S transport system, permease component
HACEDBDI_01373 2e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HACEDBDI_01374 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
HACEDBDI_01375 1.3e-90 yjlB S Cupin domain
HACEDBDI_01376 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HACEDBDI_01377 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HACEDBDI_01378 7.9e-279 uxaC 5.3.1.12 G glucuronate isomerase
HACEDBDI_01379 2.1e-247 yjmB G symporter YjmB
HACEDBDI_01380 4.9e-190 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HACEDBDI_01381 2.8e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HACEDBDI_01382 2.2e-134 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HACEDBDI_01383 9.4e-61 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HACEDBDI_01384 1.3e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HACEDBDI_01385 2.2e-224 exuT G Sugar (and other) transporter
HACEDBDI_01386 1.2e-183 exuR K transcriptional
HACEDBDI_01387 1.5e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HACEDBDI_01388 8.1e-282 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HACEDBDI_01389 7.4e-130 MA20_18170 S membrane transporter protein
HACEDBDI_01390 2.3e-78 yjoA S DinB family
HACEDBDI_01391 2.1e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HACEDBDI_01392 1e-212 S response regulator aspartate phosphatase
HACEDBDI_01394 6.3e-41 S YCII-related domain
HACEDBDI_01395 1.6e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HACEDBDI_01396 6.1e-61 yjqA S Bacterial PH domain
HACEDBDI_01397 3.3e-109 yjqB S Pfam:DUF867
HACEDBDI_01398 4.4e-160 ydbD P Catalase
HACEDBDI_01399 1.6e-111 xkdA E IrrE N-terminal-like domain
HACEDBDI_01400 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HACEDBDI_01402 1.7e-156 xkdB K sequence-specific DNA binding
HACEDBDI_01403 4.1e-118 xkdC L Bacterial dnaA protein
HACEDBDI_01406 2.3e-09 yqaO S Phage-like element PBSX protein XtrA
HACEDBDI_01407 2.4e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HACEDBDI_01408 1.2e-138 xtmA L phage terminase small subunit
HACEDBDI_01409 1.2e-252 xtmB S phage terminase, large subunit
HACEDBDI_01410 1.6e-285 yqbA S portal protein
HACEDBDI_01411 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HACEDBDI_01412 5.8e-169 xkdG S Phage capsid family
HACEDBDI_01413 5.1e-63 yqbG S Protein of unknown function (DUF3199)
HACEDBDI_01414 3.3e-64 yqbH S Domain of unknown function (DUF3599)
HACEDBDI_01415 9.9e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
HACEDBDI_01416 1.9e-77 xkdJ
HACEDBDI_01417 9.3e-256 xkdK S Phage tail sheath C-terminal domain
HACEDBDI_01418 6.1e-76 xkdM S Phage tail tube protein
HACEDBDI_01419 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
HACEDBDI_01420 0.0 xkdO L Transglycosylase SLT domain
HACEDBDI_01421 9.2e-121 xkdP S Lysin motif
HACEDBDI_01422 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
HACEDBDI_01423 3e-38 xkdR S Protein of unknown function (DUF2577)
HACEDBDI_01424 3.1e-69 xkdS S Protein of unknown function (DUF2634)
HACEDBDI_01425 7.4e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HACEDBDI_01426 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HACEDBDI_01427 6.7e-41
HACEDBDI_01428 1.4e-100
HACEDBDI_01430 4.9e-14 xkdX
HACEDBDI_01431 3.9e-28 xhlA S Haemolysin XhlA
HACEDBDI_01432 9.3e-40 xhlB S SPP1 phage holin
HACEDBDI_01433 4.2e-161 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HACEDBDI_01435 6.7e-23 spoIISB S Stage II sporulation protein SB
HACEDBDI_01436 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HACEDBDI_01437 5.8e-175 pit P phosphate transporter
HACEDBDI_01438 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HACEDBDI_01439 4.8e-238 steT E amino acid
HACEDBDI_01440 6.7e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HACEDBDI_01441 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HACEDBDI_01442 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HACEDBDI_01444 2.6e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HACEDBDI_01445 2.4e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HACEDBDI_01446 5.1e-153 dppA E D-aminopeptidase
HACEDBDI_01447 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HACEDBDI_01448 4.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HACEDBDI_01449 1.3e-187 dppD P Belongs to the ABC transporter superfamily
HACEDBDI_01450 0.0 dppE E ABC transporter substrate-binding protein
HACEDBDI_01452 4.5e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HACEDBDI_01453 4.4e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HACEDBDI_01454 3.1e-164 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HACEDBDI_01455 7.2e-186 ykfD E Belongs to the ABC transporter superfamily
HACEDBDI_01456 3.1e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
HACEDBDI_01457 1.2e-160 ykgA E Amidinotransferase
HACEDBDI_01458 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HACEDBDI_01459 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HACEDBDI_01460 5.5e-09
HACEDBDI_01461 2.3e-128 ykjA S Protein of unknown function (DUF421)
HACEDBDI_01462 4.8e-96 ykkA S Protein of unknown function (DUF664)
HACEDBDI_01463 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HACEDBDI_01464 3.5e-55 ykkC P Multidrug resistance protein
HACEDBDI_01465 7e-50 ykkD P Multidrug resistance protein
HACEDBDI_01466 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HACEDBDI_01467 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HACEDBDI_01468 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HACEDBDI_01469 1.3e-70 ohrA O Organic hydroperoxide resistance protein
HACEDBDI_01470 4.8e-73 ohrR K COG1846 Transcriptional regulators
HACEDBDI_01471 2.4e-71 ohrB O Organic hydroperoxide resistance protein
HACEDBDI_01472 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HACEDBDI_01473 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HACEDBDI_01474 5e-176 isp O Belongs to the peptidase S8 family
HACEDBDI_01475 3.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HACEDBDI_01476 5.3e-136 ykoC P Cobalt transport protein
HACEDBDI_01477 1.6e-302 P ABC transporter, ATP-binding protein
HACEDBDI_01478 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
HACEDBDI_01479 5.1e-110 ykoF S YKOF-related Family
HACEDBDI_01480 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACEDBDI_01481 2e-242 ykoH 2.7.13.3 T Histidine kinase
HACEDBDI_01482 1.2e-112 ykoI S Peptidase propeptide and YPEB domain
HACEDBDI_01483 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
HACEDBDI_01486 2.2e-222 mgtE P Acts as a magnesium transporter
HACEDBDI_01487 1.4e-53 tnrA K transcriptional
HACEDBDI_01488 5.9e-18
HACEDBDI_01489 6.9e-26 ykoL
HACEDBDI_01490 1.3e-81 mhqR K transcriptional
HACEDBDI_01491 8.9e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HACEDBDI_01492 2.7e-97 ykoP G polysaccharide deacetylase
HACEDBDI_01493 8.6e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HACEDBDI_01494 0.0 ykoS
HACEDBDI_01495 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HACEDBDI_01496 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HACEDBDI_01497 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HACEDBDI_01498 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HACEDBDI_01499 2.7e-109 ykoX S membrane-associated protein
HACEDBDI_01500 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HACEDBDI_01501 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACEDBDI_01502 7.7e-107 rsgI S Anti-sigma factor N-terminus
HACEDBDI_01503 1.9e-26 sspD S small acid-soluble spore protein
HACEDBDI_01504 3.3e-124 ykrK S Domain of unknown function (DUF1836)
HACEDBDI_01505 3.5e-155 htpX O Belongs to the peptidase M48B family
HACEDBDI_01506 1.8e-232 ktrB P COG0168 Trk-type K transport systems, membrane components
HACEDBDI_01507 1.2e-10 ydfR S Protein of unknown function (DUF421)
HACEDBDI_01508 4.1e-18 ykzE
HACEDBDI_01509 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HACEDBDI_01510 0.0 kinE 2.7.13.3 T Histidine kinase
HACEDBDI_01511 1.6e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HACEDBDI_01513 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HACEDBDI_01514 8.3e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HACEDBDI_01515 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HACEDBDI_01516 2.9e-229 mtnE 2.6.1.83 E Aminotransferase
HACEDBDI_01517 1.2e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HACEDBDI_01518 2.1e-134 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HACEDBDI_01519 2.3e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HACEDBDI_01520 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HACEDBDI_01521 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
HACEDBDI_01522 6.4e-09 S Spo0E like sporulation regulatory protein
HACEDBDI_01523 1.5e-63 eag
HACEDBDI_01524 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HACEDBDI_01525 1.3e-75 ykvE K transcriptional
HACEDBDI_01526 2.5e-125 motB N Flagellar motor protein
HACEDBDI_01527 2.7e-138 motA N flagellar motor
HACEDBDI_01528 0.0 clpE O Belongs to the ClpA ClpB family
HACEDBDI_01529 7.4e-181 ykvI S membrane
HACEDBDI_01530 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HACEDBDI_01531 1.4e-80 queD 4.1.2.50, 4.2.3.12 H synthase
HACEDBDI_01532 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HACEDBDI_01533 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HACEDBDI_01534 2.9e-60 ykvN K Transcriptional regulator
HACEDBDI_01535 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
HACEDBDI_01536 5.6e-46 ykvR S Protein of unknown function (DUF3219)
HACEDBDI_01537 6e-25 ykvS S protein conserved in bacteria
HACEDBDI_01538 2.7e-28
HACEDBDI_01539 7e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
HACEDBDI_01540 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HACEDBDI_01541 4.9e-90 stoA CO thiol-disulfide
HACEDBDI_01542 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HACEDBDI_01543 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HACEDBDI_01545 1.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
HACEDBDI_01547 7.6e-128 glcT K antiterminator
HACEDBDI_01548 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACEDBDI_01549 2.1e-39 ptsH G phosphocarrier protein HPr
HACEDBDI_01550 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HACEDBDI_01551 2.1e-38 splA S Transcriptional regulator
HACEDBDI_01552 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
HACEDBDI_01553 2e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HACEDBDI_01554 2.8e-258 mcpC NT chemotaxis protein
HACEDBDI_01555 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HACEDBDI_01556 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
HACEDBDI_01557 7e-120 ykwD J protein with SCP PR1 domains
HACEDBDI_01558 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HACEDBDI_01559 0.0 pilS 2.7.13.3 T Histidine kinase
HACEDBDI_01560 2.6e-222 patA 2.6.1.1 E Aminotransferase
HACEDBDI_01561 1.3e-15
HACEDBDI_01562 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HACEDBDI_01563 1.7e-84 ykyB S YkyB-like protein
HACEDBDI_01564 2.8e-238 ykuC EGP Major facilitator Superfamily
HACEDBDI_01565 1.8e-87 ykuD S protein conserved in bacteria
HACEDBDI_01566 1.4e-164 ykuE S Metallophosphoesterase
HACEDBDI_01567 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACEDBDI_01568 1.1e-233 ykuI T Diguanylate phosphodiesterase
HACEDBDI_01569 3.9e-37 ykuJ S protein conserved in bacteria
HACEDBDI_01570 2.2e-93 ykuK S Ribonuclease H-like
HACEDBDI_01571 6.6e-27 ykzF S Antirepressor AbbA
HACEDBDI_01572 1.6e-76 ykuL S CBS domain
HACEDBDI_01573 3.5e-168 ccpC K Transcriptional regulator
HACEDBDI_01574 1.7e-84 fld C Flavodoxin domain
HACEDBDI_01575 6.7e-175 ykuO
HACEDBDI_01576 3.9e-78 fld C Flavodoxin
HACEDBDI_01577 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HACEDBDI_01578 2.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HACEDBDI_01579 9e-37 ykuS S Belongs to the UPF0180 family
HACEDBDI_01580 8.8e-142 ykuT M Mechanosensitive ion channel
HACEDBDI_01581 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HACEDBDI_01582 4.1e-80 ykuV CO thiol-disulfide
HACEDBDI_01583 1.5e-93 rok K Repressor of ComK
HACEDBDI_01584 1e-144 yknT
HACEDBDI_01585 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HACEDBDI_01586 2e-191 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HACEDBDI_01587 2.4e-245 moeA 2.10.1.1 H molybdopterin
HACEDBDI_01588 4.9e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HACEDBDI_01589 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HACEDBDI_01590 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HACEDBDI_01591 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HACEDBDI_01592 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HACEDBDI_01593 1.4e-114 yknW S Yip1 domain
HACEDBDI_01594 9.5e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HACEDBDI_01595 2.5e-124 macB V ABC transporter, ATP-binding protein
HACEDBDI_01596 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HACEDBDI_01597 1.2e-135 fruR K Transcriptional regulator
HACEDBDI_01598 4e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HACEDBDI_01599 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HACEDBDI_01600 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HACEDBDI_01601 8.1e-39 ykoA
HACEDBDI_01602 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HACEDBDI_01603 3.1e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HACEDBDI_01604 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HACEDBDI_01605 1.1e-12 S Uncharacterized protein YkpC
HACEDBDI_01606 3.8e-182 mreB D Rod-share determining protein MreBH
HACEDBDI_01607 1.5e-43 abrB K of stationary sporulation gene expression
HACEDBDI_01608 1e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HACEDBDI_01609 2.1e-154 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HACEDBDI_01610 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HACEDBDI_01611 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HACEDBDI_01612 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HACEDBDI_01613 8.2e-31 ykzG S Belongs to the UPF0356 family
HACEDBDI_01614 5.5e-147 ykrA S hydrolases of the HAD superfamily
HACEDBDI_01615 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HACEDBDI_01617 1.1e-107 recN L Putative cell-wall binding lipoprotein
HACEDBDI_01618 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HACEDBDI_01619 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HACEDBDI_01620 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HACEDBDI_01621 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HACEDBDI_01622 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HACEDBDI_01623 1e-276 speA 4.1.1.19 E Arginine
HACEDBDI_01624 1.7e-41 yktA S Belongs to the UPF0223 family
HACEDBDI_01625 4.6e-117 yktB S Belongs to the UPF0637 family
HACEDBDI_01626 7.2e-26 ykzI
HACEDBDI_01627 4.3e-149 suhB 3.1.3.25 G Inositol monophosphatase
HACEDBDI_01628 3.8e-76 ykzC S Acetyltransferase (GNAT) family
HACEDBDI_01629 8.7e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HACEDBDI_01630 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HACEDBDI_01631 0.0 ylaA
HACEDBDI_01632 2.7e-42 ylaB
HACEDBDI_01633 3.3e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HACEDBDI_01634 1.2e-11 sigC S Putative zinc-finger
HACEDBDI_01635 2.6e-37 ylaE
HACEDBDI_01636 8.2e-22 S Family of unknown function (DUF5325)
HACEDBDI_01637 0.0 typA T GTP-binding protein TypA
HACEDBDI_01638 7.2e-47 ylaH S YlaH-like protein
HACEDBDI_01639 5.6e-32 ylaI S protein conserved in bacteria
HACEDBDI_01640 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HACEDBDI_01641 1e-248 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HACEDBDI_01642 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HACEDBDI_01643 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HACEDBDI_01644 8.7e-44 ylaN S Belongs to the UPF0358 family
HACEDBDI_01645 2.5e-212 ftsW D Belongs to the SEDS family
HACEDBDI_01646 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HACEDBDI_01647 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HACEDBDI_01648 4.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HACEDBDI_01649 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HACEDBDI_01650 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HACEDBDI_01651 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HACEDBDI_01652 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HACEDBDI_01653 1.5e-166 ctaG S cytochrome c oxidase
HACEDBDI_01654 7e-62 ylbA S YugN-like family
HACEDBDI_01655 2.6e-74 ylbB T COG0517 FOG CBS domain
HACEDBDI_01656 2.8e-199 ylbC S protein with SCP PR1 domains
HACEDBDI_01657 2.6e-62 ylbD S Putative coat protein
HACEDBDI_01658 6.7e-37 ylbE S YlbE-like protein
HACEDBDI_01659 1.8e-75 ylbF S Belongs to the UPF0342 family
HACEDBDI_01660 7.5e-39 ylbG S UPF0298 protein
HACEDBDI_01661 5.4e-98 rsmD 2.1.1.171 L Methyltransferase
HACEDBDI_01662 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HACEDBDI_01663 9.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
HACEDBDI_01664 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HACEDBDI_01665 6.8e-187 ylbL T Belongs to the peptidase S16 family
HACEDBDI_01666 3e-229 ylbM S Belongs to the UPF0348 family
HACEDBDI_01668 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HACEDBDI_01669 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HACEDBDI_01670 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HACEDBDI_01671 1.5e-88 ylbP K n-acetyltransferase
HACEDBDI_01672 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HACEDBDI_01673 6e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HACEDBDI_01674 2.9e-78 mraZ K Belongs to the MraZ family
HACEDBDI_01675 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HACEDBDI_01676 3.7e-44 ftsL D Essential cell division protein
HACEDBDI_01677 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HACEDBDI_01678 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HACEDBDI_01679 8.9e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HACEDBDI_01680 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HACEDBDI_01681 2.2e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HACEDBDI_01682 5.7e-186 spoVE D Belongs to the SEDS family
HACEDBDI_01683 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HACEDBDI_01684 9e-167 murB 1.3.1.98 M cell wall formation
HACEDBDI_01685 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HACEDBDI_01686 2.4e-103 ylxW S protein conserved in bacteria
HACEDBDI_01687 3e-102 ylxX S protein conserved in bacteria
HACEDBDI_01688 6.2e-58 sbp S small basic protein
HACEDBDI_01689 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HACEDBDI_01690 4.4e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HACEDBDI_01691 0.0 bpr O COG1404 Subtilisin-like serine proteases
HACEDBDI_01693 8.9e-170 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HACEDBDI_01694 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACEDBDI_01695 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACEDBDI_01696 5.3e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HACEDBDI_01697 2.2e-251 argE 3.5.1.16 E Acetylornithine deacetylase
HACEDBDI_01698 2.4e-37 ylmC S sporulation protein
HACEDBDI_01699 3.5e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HACEDBDI_01700 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HACEDBDI_01701 6.7e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HACEDBDI_01702 1.3e-39 yggT S membrane
HACEDBDI_01703 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HACEDBDI_01704 2.6e-67 divIVA D Cell division initiation protein
HACEDBDI_01705 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HACEDBDI_01706 3.8e-63 dksA T COG1734 DnaK suppressor protein
HACEDBDI_01707 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HACEDBDI_01708 4.2e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HACEDBDI_01709 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HACEDBDI_01710 9e-232 pyrP F Xanthine uracil
HACEDBDI_01711 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HACEDBDI_01712 3.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HACEDBDI_01713 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HACEDBDI_01714 0.0 carB 6.3.5.5 F Belongs to the CarB family
HACEDBDI_01715 3.4e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HACEDBDI_01716 1e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HACEDBDI_01717 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HACEDBDI_01718 7.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HACEDBDI_01720 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HACEDBDI_01721 1.4e-179 cysP P phosphate transporter
HACEDBDI_01722 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HACEDBDI_01723 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HACEDBDI_01724 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HACEDBDI_01725 2.1e-143 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HACEDBDI_01726 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HACEDBDI_01727 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HACEDBDI_01728 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HACEDBDI_01729 2.4e-156 yloC S stress-induced protein
HACEDBDI_01730 1.5e-40 ylzA S Belongs to the UPF0296 family
HACEDBDI_01731 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HACEDBDI_01732 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HACEDBDI_01733 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HACEDBDI_01734 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HACEDBDI_01735 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HACEDBDI_01736 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HACEDBDI_01737 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HACEDBDI_01738 9e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HACEDBDI_01739 1.6e-140 stp 3.1.3.16 T phosphatase
HACEDBDI_01740 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HACEDBDI_01741 7.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HACEDBDI_01742 9.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HACEDBDI_01743 4.5e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
HACEDBDI_01744 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HACEDBDI_01745 5.5e-59 asp S protein conserved in bacteria
HACEDBDI_01746 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
HACEDBDI_01747 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HACEDBDI_01748 1.3e-154 sdaAA 4.3.1.17 E L-serine dehydratase
HACEDBDI_01749 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HACEDBDI_01750 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HACEDBDI_01751 2.1e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HACEDBDI_01752 1.9e-167 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HACEDBDI_01753 1.4e-128 IQ reductase
HACEDBDI_01754 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HACEDBDI_01755 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HACEDBDI_01756 0.0 smc D Required for chromosome condensation and partitioning
HACEDBDI_01757 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HACEDBDI_01758 2.9e-87
HACEDBDI_01759 2.1e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HACEDBDI_01760 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HACEDBDI_01761 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HACEDBDI_01762 4.5e-36 ylqC S Belongs to the UPF0109 family
HACEDBDI_01763 1.4e-60 ylqD S YlqD protein
HACEDBDI_01764 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HACEDBDI_01765 2.7e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HACEDBDI_01766 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HACEDBDI_01767 7.9e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HACEDBDI_01768 2.2e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HACEDBDI_01769 1.8e-288 ylqG
HACEDBDI_01770 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HACEDBDI_01771 7.6e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HACEDBDI_01772 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HACEDBDI_01773 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HACEDBDI_01774 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HACEDBDI_01775 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HACEDBDI_01776 2.5e-169 xerC L tyrosine recombinase XerC
HACEDBDI_01777 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HACEDBDI_01778 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HACEDBDI_01779 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HACEDBDI_01780 8.8e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HACEDBDI_01781 3.4e-74 flgC N Belongs to the flagella basal body rod proteins family
HACEDBDI_01782 1.9e-31 fliE N Flagellar hook-basal body
HACEDBDI_01783 7e-255 fliF N The M ring may be actively involved in energy transduction
HACEDBDI_01784 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HACEDBDI_01785 8.2e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HACEDBDI_01786 2.1e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HACEDBDI_01787 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HACEDBDI_01788 5.5e-35 ylxF S MgtE intracellular N domain
HACEDBDI_01789 1.7e-215 fliK N Flagellar hook-length control protein
HACEDBDI_01790 1.7e-72 flgD N Flagellar basal body rod modification protein
HACEDBDI_01791 1.6e-135 flgG N Flagellar basal body rod
HACEDBDI_01792 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HACEDBDI_01793 2e-180 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HACEDBDI_01794 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HACEDBDI_01795 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HACEDBDI_01796 6e-96 fliZ N Flagellar biosynthesis protein, FliO
HACEDBDI_01797 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HACEDBDI_01798 2.2e-36 fliQ N Role in flagellar biosynthesis
HACEDBDI_01799 4e-131 fliR N Flagellar biosynthetic protein FliR
HACEDBDI_01800 3.1e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HACEDBDI_01801 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HACEDBDI_01802 6.8e-201 flhF N Flagellar biosynthesis regulator FlhF
HACEDBDI_01803 2.8e-157 flhG D Belongs to the ParA family
HACEDBDI_01804 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HACEDBDI_01805 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HACEDBDI_01806 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HACEDBDI_01807 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HACEDBDI_01808 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HACEDBDI_01809 7.4e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACEDBDI_01810 3.1e-76 ylxL
HACEDBDI_01811 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HACEDBDI_01812 1.4e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HACEDBDI_01813 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HACEDBDI_01814 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HACEDBDI_01815 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HACEDBDI_01816 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HACEDBDI_01817 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HACEDBDI_01818 1.5e-225 rasP M zinc metalloprotease
HACEDBDI_01819 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HACEDBDI_01820 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HACEDBDI_01822 1.4e-137 spaB S Lantibiotic dehydratase, C terminus
HACEDBDI_01823 6.9e-102 spaT V ABC transporter
HACEDBDI_01824 1.3e-51 spaC2 V PFAM Lanthionine synthetase
HACEDBDI_01825 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HACEDBDI_01826 1.1e-203 nusA K Participates in both transcription termination and antitermination
HACEDBDI_01827 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HACEDBDI_01828 3.1e-47 ylxQ J ribosomal protein
HACEDBDI_01829 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HACEDBDI_01830 3.9e-44 ylxP S protein conserved in bacteria
HACEDBDI_01831 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HACEDBDI_01832 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HACEDBDI_01833 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HACEDBDI_01834 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HACEDBDI_01835 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HACEDBDI_01836 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HACEDBDI_01837 4.4e-233 pepR S Belongs to the peptidase M16 family
HACEDBDI_01838 2.6e-42 ymxH S YlmC YmxH family
HACEDBDI_01839 6.6e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HACEDBDI_01840 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HACEDBDI_01841 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HACEDBDI_01842 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HACEDBDI_01843 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HACEDBDI_01844 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HACEDBDI_01845 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HACEDBDI_01846 4.4e-32 S YlzJ-like protein
HACEDBDI_01847 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HACEDBDI_01848 1.4e-133 ymfC K Transcriptional regulator
HACEDBDI_01849 3.8e-205 ymfD EGP Major facilitator Superfamily
HACEDBDI_01850 7.8e-233 ymfF S Peptidase M16
HACEDBDI_01851 1.4e-242 ymfH S zinc protease
HACEDBDI_01852 1.9e-127 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HACEDBDI_01853 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HACEDBDI_01854 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HACEDBDI_01855 1.9e-124 ymfM S protein conserved in bacteria
HACEDBDI_01856 6.1e-100 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HACEDBDI_01857 2.1e-235 cinA 3.5.1.42 S Belongs to the CinA family
HACEDBDI_01858 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HACEDBDI_01859 3.5e-211 pbpX V Beta-lactamase
HACEDBDI_01860 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HACEDBDI_01861 1.9e-152 ymdB S protein conserved in bacteria
HACEDBDI_01862 1.2e-36 spoVS S Stage V sporulation protein S
HACEDBDI_01863 2.8e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HACEDBDI_01864 1.8e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HACEDBDI_01865 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HACEDBDI_01866 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HACEDBDI_01867 2.2e-88 cotE S Spore coat protein
HACEDBDI_01868 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HACEDBDI_01869 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HACEDBDI_01870 9.9e-69 S Regulatory protein YrvL
HACEDBDI_01871 3e-96 ymcC S Membrane
HACEDBDI_01872 3.3e-104 pksA K Transcriptional regulator
HACEDBDI_01873 4.4e-61 ymzB
HACEDBDI_01874 2.3e-161 ymaE S Metallo-beta-lactamase superfamily
HACEDBDI_01875 8.6e-251 aprX O Belongs to the peptidase S8 family
HACEDBDI_01876 1.9e-07 K Transcriptional regulator
HACEDBDI_01877 2.1e-126 ymaC S Replication protein
HACEDBDI_01878 1e-78 ymaD O redox protein, regulator of disulfide bond formation
HACEDBDI_01879 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HACEDBDI_01880 5.4e-50 ebrA P Small Multidrug Resistance protein
HACEDBDI_01882 2.1e-46 ymaF S YmaF family
HACEDBDI_01883 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HACEDBDI_01884 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HACEDBDI_01885 8.2e-23
HACEDBDI_01886 4.5e-22 ymzA
HACEDBDI_01887 1.6e-48 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HACEDBDI_01888 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HACEDBDI_01889 5.9e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HACEDBDI_01890 2.9e-108 ymaB
HACEDBDI_01891 1.1e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HACEDBDI_01892 6.6e-176 spoVK O stage V sporulation protein K
HACEDBDI_01893 2.3e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HACEDBDI_01894 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HACEDBDI_01895 4.3e-68 glnR K transcriptional
HACEDBDI_01896 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
HACEDBDI_01897 1.3e-38 L Arm DNA-binding domain
HACEDBDI_01898 4.5e-82 dnaB 3.6.4.12 L replicative DNA helicase
HACEDBDI_01900 7.1e-51 wecC 1.1.1.336 M ArpU family transcriptional regulator
HACEDBDI_01901 3.2e-27 S PFAM FRG domain
HACEDBDI_01902 1.2e-48 V HNH endonuclease
HACEDBDI_01903 7.2e-23
HACEDBDI_01904 8.3e-23
HACEDBDI_01905 3.3e-67 Q Collagen triple helix repeat (20 copies)
HACEDBDI_01906 4.9e-93 M Glycosyltransferase like family
HACEDBDI_01907 9.9e-121 H Methionine biosynthesis protein MetW
HACEDBDI_01908 1.1e-195 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HACEDBDI_01909 3.2e-216 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
HACEDBDI_01910 1.3e-96 ynaD J Acetyltransferase (GNAT) domain
HACEDBDI_01912 5.7e-73 S CAAX protease self-immunity
HACEDBDI_01913 4.7e-08 S Uncharacterised protein family (UPF0715)
HACEDBDI_01914 3.4e-22 K Cro/C1-type HTH DNA-binding domain
HACEDBDI_01915 3.5e-117 ynaE S Domain of unknown function (DUF3885)
HACEDBDI_01916 2.2e-39 ynaF
HACEDBDI_01918 2e-77 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HACEDBDI_01919 8.1e-186 xynT G MFS/sugar transport protein
HACEDBDI_01920 9.9e-46 xynT G MFS/sugar transport protein
HACEDBDI_01921 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HACEDBDI_01922 1e-215 xylR GK ROK family
HACEDBDI_01923 4.4e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HACEDBDI_01924 2.5e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HACEDBDI_01925 6.4e-111 yokF 3.1.31.1 L RNA catabolic process
HACEDBDI_01926 9.4e-256 iolT EGP Major facilitator Superfamily
HACEDBDI_01927 1.7e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HACEDBDI_01928 2.2e-81 yncE S Protein of unknown function (DUF2691)
HACEDBDI_01929 4.1e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HACEDBDI_01932 1.9e-163 S Thymidylate synthase
HACEDBDI_01934 1.6e-132 S Domain of unknown function, YrpD
HACEDBDI_01937 7.9e-25 tatA U protein secretion
HACEDBDI_01938 5.3e-71
HACEDBDI_01939 2.6e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HACEDBDI_01942 1.6e-285 gerAA EG Spore germination protein
HACEDBDI_01943 3.6e-178 gerAB U Spore germination
HACEDBDI_01944 6.7e-218 gerLC S Spore germination protein
HACEDBDI_01945 1.6e-151 yndG S DoxX-like family
HACEDBDI_01946 2.1e-114 yndH S Domain of unknown function (DUF4166)
HACEDBDI_01947 4.4e-305 yndJ S YndJ-like protein
HACEDBDI_01949 5.8e-135 yndL S Replication protein
HACEDBDI_01950 5.8e-74 yndM S Protein of unknown function (DUF2512)
HACEDBDI_01951 4.9e-78 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HACEDBDI_01952 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HACEDBDI_01953 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HACEDBDI_01954 2.5e-110 yneB L resolvase
HACEDBDI_01955 4.8e-32 ynzC S UPF0291 protein
HACEDBDI_01956 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HACEDBDI_01957 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HACEDBDI_01958 1.8e-28 yneF S UPF0154 protein
HACEDBDI_01959 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HACEDBDI_01960 2.1e-126 ccdA O cytochrome c biogenesis protein
HACEDBDI_01961 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HACEDBDI_01962 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HACEDBDI_01963 4.2e-74 yneK S Protein of unknown function (DUF2621)
HACEDBDI_01964 1.2e-64 hspX O Spore coat protein
HACEDBDI_01965 3.9e-19 sspP S Belongs to the SspP family
HACEDBDI_01966 2.5e-14 sspO S Belongs to the SspO family
HACEDBDI_01967 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HACEDBDI_01968 1e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HACEDBDI_01970 3.1e-08 sspN S Small acid-soluble spore protein N family
HACEDBDI_01971 3.9e-35 tlp S Belongs to the Tlp family
HACEDBDI_01972 1.2e-73 yneP S Thioesterase-like superfamily
HACEDBDI_01973 2.2e-53 yneQ
HACEDBDI_01974 4.1e-49 yneR S Belongs to the HesB IscA family
HACEDBDI_01975 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HACEDBDI_01976 6.6e-69 yccU S CoA-binding protein
HACEDBDI_01977 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HACEDBDI_01978 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HACEDBDI_01979 2.3e-12
HACEDBDI_01980 8.6e-57 ynfC
HACEDBDI_01981 2.4e-251 agcS E Sodium alanine symporter
HACEDBDI_01982 7.1e-283 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HACEDBDI_01984 6.9e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HACEDBDI_01985 1.4e-292 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HACEDBDI_01986 2e-79 yngA S membrane
HACEDBDI_01987 1.3e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HACEDBDI_01988 5.5e-104 yngC S membrane-associated protein
HACEDBDI_01989 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
HACEDBDI_01990 5.9e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HACEDBDI_01991 1.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HACEDBDI_01992 7.5e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HACEDBDI_01993 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HACEDBDI_01994 4.7e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HACEDBDI_01995 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HACEDBDI_01996 1.1e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HACEDBDI_01997 1.4e-23 S Family of unknown function (DUF5367)
HACEDBDI_01998 3.8e-303 yngK T Glycosyl hydrolase-like 10
HACEDBDI_01999 1.1e-63 yngL S Protein of unknown function (DUF1360)
HACEDBDI_02000 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HACEDBDI_02001 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACEDBDI_02002 2.9e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HACEDBDI_02003 1.6e-185 yoxA 5.1.3.3 G Aldose 1-epimerase
HACEDBDI_02004 2.3e-246 yoeA V MATE efflux family protein
HACEDBDI_02005 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HACEDBDI_02007 3.8e-96 L Integrase
HACEDBDI_02008 3e-34 yoeD G Helix-turn-helix domain
HACEDBDI_02009 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HACEDBDI_02010 4.4e-155 gltR1 K Transcriptional regulator
HACEDBDI_02011 1.3e-165 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HACEDBDI_02012 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HACEDBDI_02013 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HACEDBDI_02014 7.8e-155 gltC K Transcriptional regulator
HACEDBDI_02015 1.1e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HACEDBDI_02016 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HACEDBDI_02017 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HACEDBDI_02018 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HACEDBDI_02019 8.3e-40 yoxC S Bacterial protein of unknown function (DUF948)
HACEDBDI_02020 2.9e-134 yoxB
HACEDBDI_02021 1e-93 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HACEDBDI_02022 1.1e-234 yoaB EGP Major facilitator Superfamily
HACEDBDI_02023 8.5e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HACEDBDI_02024 3.4e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HACEDBDI_02025 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HACEDBDI_02026 7.2e-33 yoaF
HACEDBDI_02027 2.9e-08 ywlA S Uncharacterised protein family (UPF0715)
HACEDBDI_02028 2.6e-13
HACEDBDI_02029 7.7e-35 S Protein of unknown function (DUF4025)
HACEDBDI_02030 5e-179 mcpU NT methyl-accepting chemotaxis protein
HACEDBDI_02031 3.7e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HACEDBDI_02032 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HACEDBDI_02033 2.3e-111 yoaK S Membrane
HACEDBDI_02034 2.1e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HACEDBDI_02035 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
HACEDBDI_02038 2.1e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
HACEDBDI_02041 8.9e-84
HACEDBDI_02042 9.3e-172 yoaR V vancomycin resistance protein
HACEDBDI_02043 2.8e-74 yoaS S Protein of unknown function (DUF2975)
HACEDBDI_02044 4.4e-30 yozG K Transcriptional regulator
HACEDBDI_02045 2.4e-147 yoaT S Protein of unknown function (DUF817)
HACEDBDI_02046 1.1e-158 yoaU K LysR substrate binding domain
HACEDBDI_02047 2.5e-158 yijE EG EamA-like transporter family
HACEDBDI_02048 1.6e-76 yoaW
HACEDBDI_02049 2.1e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HACEDBDI_02050 2.4e-167 bla 3.5.2.6 V beta-lactamase
HACEDBDI_02053 2.8e-238 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HACEDBDI_02054 1.1e-139 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HACEDBDI_02055 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HACEDBDI_02056 8.8e-37 S TM2 domain
HACEDBDI_02058 1.3e-31 yoaF
HACEDBDI_02059 7.6e-136
HACEDBDI_02060 1.7e-16 FG Scavenger mRNA decapping enzyme C-term binding
HACEDBDI_02067 3.7e-51 ynaF
HACEDBDI_02068 1.6e-101 ynaE S Domain of unknown function (DUF3885)
HACEDBDI_02069 9.4e-26 K Cro/C1-type HTH DNA-binding domain
HACEDBDI_02070 6.2e-81 yoaW
HACEDBDI_02071 2.9e-09 ywlA S Uncharacterised protein family (UPF0715)
HACEDBDI_02073 5.8e-76
HACEDBDI_02074 2.1e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
HACEDBDI_02075 5e-17
HACEDBDI_02077 3.1e-87 S response regulator aspartate phosphatase
HACEDBDI_02079 3.7e-43 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HACEDBDI_02080 5.7e-22 Q Methyltransferase
HACEDBDI_02081 3.5e-35 2.7.7.73, 2.7.7.80 H ThiF family
HACEDBDI_02082 2e-32 Q Methyltransferase domain
HACEDBDI_02083 5.5e-26 G Major Facilitator Superfamily
HACEDBDI_02084 3.4e-166 S impB/mucB/samB family C-terminal domain
HACEDBDI_02085 1.5e-46 S YolD-like protein
HACEDBDI_02086 6.3e-10
HACEDBDI_02088 1.4e-33 J Acetyltransferase (GNAT) domain
HACEDBDI_02089 4.1e-30 J Acetyltransferase (GNAT) domain
HACEDBDI_02090 5.1e-99 yokK S SMI1 / KNR4 family
HACEDBDI_02091 1.7e-73 S SMI1-KNR4 cell-wall
HACEDBDI_02092 3e-86 S SMI1-KNR4 cell-wall
HACEDBDI_02093 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HACEDBDI_02094 1.3e-99 yokH G SMI1 / KNR4 family
HACEDBDI_02095 2.6e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HACEDBDI_02096 3.8e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HACEDBDI_02097 1e-120 yobQ K helix_turn_helix, arabinose operon control protein
HACEDBDI_02098 1e-139 yobR 2.3.1.1 J FR47-like protein
HACEDBDI_02099 2.1e-97 yobS K Transcriptional regulator
HACEDBDI_02100 4.7e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HACEDBDI_02101 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
HACEDBDI_02102 4.8e-171 yobV K WYL domain
HACEDBDI_02103 4.1e-90 yobW
HACEDBDI_02104 1e-51 czrA K transcriptional
HACEDBDI_02105 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HACEDBDI_02106 1.5e-92 yozB S membrane
HACEDBDI_02107 7e-144
HACEDBDI_02108 1.2e-93 yocC
HACEDBDI_02109 1.1e-186 yocD 3.4.17.13 V peptidase S66
HACEDBDI_02110 6.9e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HACEDBDI_02111 4.6e-197 desK 2.7.13.3 T Histidine kinase
HACEDBDI_02112 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACEDBDI_02114 6e-112 yocH CBM50 M COG1388 FOG LysM repeat
HACEDBDI_02115 0.0 recQ 3.6.4.12 L DNA helicase
HACEDBDI_02116 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HACEDBDI_02117 3.3e-83 dksA T general stress protein
HACEDBDI_02118 6.4e-54 yocL
HACEDBDI_02119 2.8e-32
HACEDBDI_02120 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HACEDBDI_02121 1.1e-40 yozN
HACEDBDI_02122 1.9e-36 yocN
HACEDBDI_02123 4.2e-56 yozO S Bacterial PH domain
HACEDBDI_02124 2.7e-31 yozC
HACEDBDI_02125 6.8e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HACEDBDI_02126 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HACEDBDI_02127 6e-165 sodA 1.15.1.1 P Superoxide dismutase
HACEDBDI_02128 6e-228 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HACEDBDI_02129 5.6e-167 yocS S -transporter
HACEDBDI_02130 5.3e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HACEDBDI_02131 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HACEDBDI_02132 0.0 yojO P Von Willebrand factor
HACEDBDI_02133 1.2e-160 yojN S ATPase family associated with various cellular activities (AAA)
HACEDBDI_02134 1.7e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HACEDBDI_02135 7.9e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HACEDBDI_02136 1.5e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HACEDBDI_02137 2.2e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HACEDBDI_02139 1.6e-244 norM V Multidrug efflux pump
HACEDBDI_02140 7.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HACEDBDI_02141 3.7e-125 yojG S deacetylase
HACEDBDI_02142 2.2e-60 yojF S Protein of unknown function (DUF1806)
HACEDBDI_02143 1.5e-43
HACEDBDI_02144 5.6e-161 rarD S -transporter
HACEDBDI_02145 8.6e-65 yozR S COG0071 Molecular chaperone (small heat shock protein)
HACEDBDI_02146 2.6e-09
HACEDBDI_02147 7.3e-60 gntP EG COG2610 H gluconate symporter and related permeases
HACEDBDI_02148 6.6e-130 gntP EG COG2610 H gluconate symporter and related permeases
HACEDBDI_02149 1.4e-63 yodA S tautomerase
HACEDBDI_02150 4.4e-55 yodB K transcriptional
HACEDBDI_02151 1.4e-107 yodC C nitroreductase
HACEDBDI_02152 4.2e-112 mhqD S Carboxylesterase
HACEDBDI_02153 1.7e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
HACEDBDI_02154 6.2e-28 S Protein of unknown function (DUF3311)
HACEDBDI_02155 5.6e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HACEDBDI_02156 5.3e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HACEDBDI_02157 5.4e-127 yodH Q Methyltransferase
HACEDBDI_02158 1.5e-23 yodI
HACEDBDI_02159 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HACEDBDI_02160 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HACEDBDI_02161 5.3e-09
HACEDBDI_02162 3.6e-54 yodL S YodL-like
HACEDBDI_02163 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
HACEDBDI_02164 2.8e-24 yozD S YozD-like protein
HACEDBDI_02166 6e-123 yodN
HACEDBDI_02167 1.4e-36 yozE S Belongs to the UPF0346 family
HACEDBDI_02168 2.9e-47 yokU S YokU-like protein, putative antitoxin
HACEDBDI_02169 1.4e-53 kamA 5.4.3.2 E lysine 2,3-aminomutase
HACEDBDI_02170 4.7e-44
HACEDBDI_02172 2.2e-89 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HACEDBDI_02173 1.9e-10 K Cro/C1-type HTH DNA-binding domain
HACEDBDI_02183 2.5e-30 sspB S spore protein
HACEDBDI_02185 8.1e-45
HACEDBDI_02187 1.6e-157 S Thymidylate synthase
HACEDBDI_02188 1.8e-38 S Protein of unknown function (DUF1643)
HACEDBDI_02191 4.9e-15 V COG4767 Glycopeptide antibiotics resistance protein
HACEDBDI_02192 3.8e-75 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HACEDBDI_02193 1.1e-34 O Glutaredoxin
HACEDBDI_02194 1.9e-181 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HACEDBDI_02196 0.0 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
HACEDBDI_02197 6.9e-63 S NrdI Flavodoxin like
HACEDBDI_02207 6.7e-24 S hydrolase activity
HACEDBDI_02211 2.5e-13
HACEDBDI_02218 2e-80 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
HACEDBDI_02223 1.1e-103 DR0488 S protein conserved in bacteria
HACEDBDI_02224 0.0 2.7.7.7 L DNA polymerase
HACEDBDI_02225 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HACEDBDI_02226 8.5e-223 L DNA primase activity
HACEDBDI_02227 1.3e-282 3.6.4.12 J DnaB-like helicase C terminal domain
HACEDBDI_02228 4.5e-85
HACEDBDI_02229 7.6e-180 L AAA domain
HACEDBDI_02230 1.2e-155
HACEDBDI_02235 0.0 M Parallel beta-helix repeats
HACEDBDI_02236 9.4e-147 S Pfam:DUF867
HACEDBDI_02237 2.1e-187
HACEDBDI_02239 1.9e-129 yoqW S Belongs to the SOS response-associated peptidase family
HACEDBDI_02240 3.5e-146 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HACEDBDI_02241 2e-65
HACEDBDI_02243 2.5e-82 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
HACEDBDI_02247 8.3e-39
HACEDBDI_02248 1.9e-49 S Protein of unknown function (DUF1273)
HACEDBDI_02252 1.1e-11 S Protein of unknown function (DUF2815)
HACEDBDI_02256 2.4e-08 S YopX protein
HACEDBDI_02257 4.3e-21
HACEDBDI_02261 1.1e-33 K Transcriptional regulator
HACEDBDI_02262 2.1e-177
HACEDBDI_02263 2e-258 S DNA-sulfur modification-associated
HACEDBDI_02264 8.9e-198 L Belongs to the 'phage' integrase family
HACEDBDI_02269 8.6e-106
HACEDBDI_02271 1.2e-14
HACEDBDI_02272 1.6e-22
HACEDBDI_02276 4.8e-08 ywlA S Uncharacterised protein family (UPF0715)
HACEDBDI_02277 3.7e-51 ynaF
HACEDBDI_02278 1.6e-101 ynaE S Domain of unknown function (DUF3885)
HACEDBDI_02279 9.4e-26 K Cro/C1-type HTH DNA-binding domain
HACEDBDI_02280 6.2e-81 yoaW
HACEDBDI_02281 2.9e-09 ywlA S Uncharacterised protein family (UPF0715)
HACEDBDI_02282 5.3e-61 S Bacteriophage abortive infection AbiH
HACEDBDI_02289 1.1e-204
HACEDBDI_02290 4.3e-40
HACEDBDI_02291 1e-42
HACEDBDI_02294 0.0 S RNA-directed RNA polymerase activity
HACEDBDI_02295 1.6e-14 L GIY-YIG type nucleases (URI domain)
HACEDBDI_02296 1.4e-116
HACEDBDI_02297 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HACEDBDI_02300 2.2e-229 S hydrolase activity
HACEDBDI_02304 7e-175
HACEDBDI_02305 0.0 gp17a S Terminase-like family
HACEDBDI_02306 1.6e-277
HACEDBDI_02307 3.4e-237
HACEDBDI_02308 7.8e-94
HACEDBDI_02309 4.8e-185
HACEDBDI_02310 1.1e-80
HACEDBDI_02311 7.9e-67
HACEDBDI_02313 7e-121
HACEDBDI_02314 5.9e-91
HACEDBDI_02315 8.1e-131
HACEDBDI_02316 1e-89
HACEDBDI_02319 5e-52
HACEDBDI_02320 2.2e-10
HACEDBDI_02321 3.3e-47
HACEDBDI_02323 1.1e-81
HACEDBDI_02324 7.5e-63
HACEDBDI_02325 5.2e-123 xerH L Belongs to the 'phage' integrase family
HACEDBDI_02326 2.2e-22
HACEDBDI_02328 2.9e-61
HACEDBDI_02329 1.4e-34
HACEDBDI_02330 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HACEDBDI_02331 1.6e-81 S Phage tail protein
HACEDBDI_02332 4.3e-294 S Pfam Transposase IS66
HACEDBDI_02333 6.4e-103
HACEDBDI_02334 8.2e-55
HACEDBDI_02336 1.3e-09 S Phage uncharacterised protein (Phage_XkdX)
HACEDBDI_02337 1.2e-176 3.5.1.28 M Ami_2
HACEDBDI_02339 2.7e-36 S Bacteriophage holin
HACEDBDI_02340 7.1e-206 S aspartate phosphatase
HACEDBDI_02342 7.6e-233 S impB/mucB/samB family C-terminal domain
HACEDBDI_02343 1.5e-50 S YolD-like protein
HACEDBDI_02345 5.1e-37
HACEDBDI_02347 5.2e-09 S Domain of unknown function (DUF4879)
HACEDBDI_02348 2.8e-99 J Acetyltransferase (GNAT) domain
HACEDBDI_02349 3.2e-109 yokK S SMI1 / KNR4 family
HACEDBDI_02350 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
HACEDBDI_02351 1.2e-302 UW nuclease activity
HACEDBDI_02352 3.1e-66 G SMI1-KNR4 cell-wall
HACEDBDI_02353 2.4e-37
HACEDBDI_02354 2.1e-107 yokF 3.1.31.1 L RNA catabolic process
HACEDBDI_02355 5.8e-81 yhbS S family acetyltransferase
HACEDBDI_02356 4.4e-278 S Recombinase
HACEDBDI_02357 4.7e-199 kamA 5.4.3.2 E lysine 2,3-aminomutase
HACEDBDI_02358 1.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HACEDBDI_02359 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
HACEDBDI_02360 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HACEDBDI_02361 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HACEDBDI_02362 2.3e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HACEDBDI_02364 5.9e-143 yiiD K acetyltransferase
HACEDBDI_02365 3.6e-254 cgeD M maturation of the outermost layer of the spore
HACEDBDI_02366 4.5e-38 cgeC
HACEDBDI_02367 3.1e-63 cgeA
HACEDBDI_02368 2e-177 cgeB S Spore maturation protein
HACEDBDI_02369 1.4e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HACEDBDI_02370 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
HACEDBDI_02371 6.4e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HACEDBDI_02372 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HACEDBDI_02373 1.6e-70 ypoP K transcriptional
HACEDBDI_02374 7.6e-223 mepA V MATE efflux family protein
HACEDBDI_02375 1.6e-28 ypmT S Uncharacterized ympT
HACEDBDI_02376 1.1e-98 ypmS S protein conserved in bacteria
HACEDBDI_02377 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HACEDBDI_02378 9.3e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HACEDBDI_02379 3.4e-39 ypmP S Protein of unknown function (DUF2535)
HACEDBDI_02380 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HACEDBDI_02381 4.7e-185 pspF K Transcriptional regulator
HACEDBDI_02382 4.2e-110 hlyIII S protein, Hemolysin III
HACEDBDI_02383 2.1e-111 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HACEDBDI_02384 1.8e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HACEDBDI_02385 1.1e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HACEDBDI_02386 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HACEDBDI_02387 7.8e-114 ypjP S YpjP-like protein
HACEDBDI_02388 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HACEDBDI_02389 1.7e-75 yphP S Belongs to the UPF0403 family
HACEDBDI_02390 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HACEDBDI_02391 1.2e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
HACEDBDI_02392 2.1e-106 ypgQ S phosphohydrolase
HACEDBDI_02393 1.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HACEDBDI_02394 8.1e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HACEDBDI_02395 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HACEDBDI_02396 7.9e-31 cspD K Cold-shock protein
HACEDBDI_02397 3.8e-16 degR
HACEDBDI_02398 8.1e-31 S Protein of unknown function (DUF2564)
HACEDBDI_02399 4.1e-29 ypeQ S Zinc-finger
HACEDBDI_02400 1.9e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HACEDBDI_02401 6.3e-120 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HACEDBDI_02402 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
HACEDBDI_02404 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HACEDBDI_02405 2e-07
HACEDBDI_02406 8.5e-38 ypbS S Protein of unknown function (DUF2533)
HACEDBDI_02407 0.0 ypbR S Dynamin family
HACEDBDI_02408 5.1e-87 ypbQ S protein conserved in bacteria
HACEDBDI_02409 2.8e-207 bcsA Q Naringenin-chalcone synthase
HACEDBDI_02410 4.8e-155 pbuX F xanthine
HACEDBDI_02411 1.1e-55 L Recombinase
HACEDBDI_02415 2.1e-21 K Cro/C1-type HTH DNA-binding domain
HACEDBDI_02417 1.6e-40
HACEDBDI_02418 2.1e-247 I Pfam Lipase (class 3)
HACEDBDI_02419 5.2e-49 S Protein of unknown function (DUF1433)
HACEDBDI_02420 8.6e-36 S Protein of unknown function (DUF1433)
HACEDBDI_02421 1.7e-11
HACEDBDI_02422 3.8e-09
HACEDBDI_02423 0.0 S peptidoglycan catabolic process
HACEDBDI_02425 7.3e-28 S Phage gp6-like head-tail connector protein
HACEDBDI_02426 3.8e-103 S P22 coat protein-protein 5 domain protein
HACEDBDI_02427 2e-74 S Domain of unknown function (DUF4355)
HACEDBDI_02428 6.7e-195 S Phage portal protein, SPP1 Gp6-like
HACEDBDI_02429 3.7e-300 S TIGRFAM Phage
HACEDBDI_02430 1e-75 tnpR1 L Resolvase, N terminal domain
HACEDBDI_02431 3.3e-52 S Helix-turn-helix of insertion element transposase
HACEDBDI_02433 2.5e-43
HACEDBDI_02434 1.1e-28
HACEDBDI_02436 2.1e-13
HACEDBDI_02437 1.1e-42 S Domain of unknown function (DUF2479)
HACEDBDI_02438 1.4e-70
HACEDBDI_02439 9.8e-52
HACEDBDI_02443 4.1e-229
HACEDBDI_02444 2e-43
HACEDBDI_02450 9.8e-57
HACEDBDI_02452 2.6e-62 pbuX F xanthine
HACEDBDI_02453 1.3e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HACEDBDI_02454 1.9e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HACEDBDI_02455 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HACEDBDI_02456 5e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HACEDBDI_02457 1.9e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HACEDBDI_02458 1.5e-186 ptxS K transcriptional
HACEDBDI_02459 1.4e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HACEDBDI_02460 1.9e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACEDBDI_02461 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HACEDBDI_02463 1.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HACEDBDI_02464 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HACEDBDI_02465 3.2e-95 ypsA S Belongs to the UPF0398 family
HACEDBDI_02466 6.6e-237 yprB L RNase_H superfamily
HACEDBDI_02467 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HACEDBDI_02468 1e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HACEDBDI_02469 1.2e-70 hspX O Belongs to the small heat shock protein (HSP20) family
HACEDBDI_02470 1.2e-48 yppG S YppG-like protein
HACEDBDI_02472 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
HACEDBDI_02475 7.7e-185 yppC S Protein of unknown function (DUF2515)
HACEDBDI_02476 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HACEDBDI_02477 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HACEDBDI_02478 8.8e-92 ypoC
HACEDBDI_02479 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HACEDBDI_02480 5.7e-129 dnaD L DNA replication protein DnaD
HACEDBDI_02481 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HACEDBDI_02482 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HACEDBDI_02483 2.2e-79 ypmB S protein conserved in bacteria
HACEDBDI_02484 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HACEDBDI_02485 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HACEDBDI_02486 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HACEDBDI_02487 1.2e-155 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HACEDBDI_02488 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HACEDBDI_02489 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HACEDBDI_02490 6.6e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HACEDBDI_02491 4.5e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HACEDBDI_02492 3.4e-129 bshB1 S proteins, LmbE homologs
HACEDBDI_02493 1.6e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HACEDBDI_02494 1.2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HACEDBDI_02495 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HACEDBDI_02496 3.1e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HACEDBDI_02497 1.3e-142 ypjB S sporulation protein
HACEDBDI_02498 6.8e-99 ypjA S membrane
HACEDBDI_02499 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HACEDBDI_02500 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HACEDBDI_02501 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HACEDBDI_02502 4.2e-77 ypiF S Protein of unknown function (DUF2487)
HACEDBDI_02503 2.8e-99 ypiB S Belongs to the UPF0302 family
HACEDBDI_02504 1e-232 S COG0457 FOG TPR repeat
HACEDBDI_02505 3.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HACEDBDI_02506 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HACEDBDI_02507 7.8e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HACEDBDI_02508 1e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HACEDBDI_02509 6.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HACEDBDI_02510 1.4e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HACEDBDI_02511 1.8e-112 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HACEDBDI_02512 1.8e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HACEDBDI_02513 7.6e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HACEDBDI_02514 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HACEDBDI_02515 7.6e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HACEDBDI_02516 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HACEDBDI_02517 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HACEDBDI_02518 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HACEDBDI_02519 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HACEDBDI_02520 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HACEDBDI_02521 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HACEDBDI_02522 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HACEDBDI_02523 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HACEDBDI_02524 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HACEDBDI_02525 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HACEDBDI_02526 6e-137 yphF
HACEDBDI_02527 1.6e-18 yphE S Protein of unknown function (DUF2768)
HACEDBDI_02528 3.6e-180 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HACEDBDI_02529 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HACEDBDI_02530 2.3e-27 ypzH
HACEDBDI_02531 3.3e-161 seaA S YIEGIA protein
HACEDBDI_02532 5.1e-102 yphA
HACEDBDI_02533 3e-07 S YpzI-like protein
HACEDBDI_02534 4.6e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HACEDBDI_02535 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HACEDBDI_02536 8.9e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HACEDBDI_02537 2.4e-23 S Family of unknown function (DUF5359)
HACEDBDI_02538 2.1e-109 ypfA M Flagellar protein YcgR
HACEDBDI_02539 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HACEDBDI_02540 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HACEDBDI_02541 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
HACEDBDI_02542 8.1e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HACEDBDI_02543 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HACEDBDI_02544 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HACEDBDI_02545 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
HACEDBDI_02546 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HACEDBDI_02547 2.2e-78 ypbE M Lysin motif
HACEDBDI_02548 1.1e-99 ypbD S metal-dependent membrane protease
HACEDBDI_02549 9.2e-286 recQ 3.6.4.12 L DNA helicase
HACEDBDI_02550 1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
HACEDBDI_02551 4.7e-41 fer C Ferredoxin
HACEDBDI_02552 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HACEDBDI_02553 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HACEDBDI_02554 9.4e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HACEDBDI_02555 1.8e-185 rsiX
HACEDBDI_02556 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HACEDBDI_02557 0.0 resE 2.7.13.3 T Histidine kinase
HACEDBDI_02558 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACEDBDI_02559 2.6e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HACEDBDI_02560 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HACEDBDI_02561 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HACEDBDI_02562 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HACEDBDI_02563 1.9e-87 spmB S Spore maturation protein
HACEDBDI_02564 3.5e-103 spmA S Spore maturation protein
HACEDBDI_02565 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HACEDBDI_02566 7.6e-97 ypuI S Protein of unknown function (DUF3907)
HACEDBDI_02567 3.5e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HACEDBDI_02568 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HACEDBDI_02569 9.4e-92 ypuF S Domain of unknown function (DUF309)
HACEDBDI_02570 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HACEDBDI_02571 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HACEDBDI_02572 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HACEDBDI_02573 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
HACEDBDI_02574 8.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HACEDBDI_02575 7.8e-55 ypuD
HACEDBDI_02576 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HACEDBDI_02577 5.6e-32 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HACEDBDI_02579 4.2e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HACEDBDI_02580 2e-36 S Pfam Transposase IS66
HACEDBDI_02581 3e-07
HACEDBDI_02586 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HACEDBDI_02587 8.1e-149 ypuA S Secreted protein
HACEDBDI_02588 7.5e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HACEDBDI_02589 3.1e-273 spoVAF EG Stage V sporulation protein AF
HACEDBDI_02590 1.4e-110 spoVAEA S stage V sporulation protein
HACEDBDI_02591 2.2e-57 spoVAEB S stage V sporulation protein
HACEDBDI_02592 3.4e-191 spoVAD I Stage V sporulation protein AD
HACEDBDI_02593 2.3e-78 spoVAC S stage V sporulation protein AC
HACEDBDI_02594 2.9e-67 spoVAB S Stage V sporulation protein AB
HACEDBDI_02595 9.6e-112 spoVAA S Stage V sporulation protein AA
HACEDBDI_02596 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACEDBDI_02597 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HACEDBDI_02598 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HACEDBDI_02599 5.3e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HACEDBDI_02600 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HACEDBDI_02601 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HACEDBDI_02602 2.6e-166 xerD L recombinase XerD
HACEDBDI_02603 3.7e-37 S Protein of unknown function (DUF4227)
HACEDBDI_02604 2.4e-80 fur P Belongs to the Fur family
HACEDBDI_02605 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HACEDBDI_02606 2.1e-29 yqkK
HACEDBDI_02607 5.5e-242 mleA 1.1.1.38 C malic enzyme
HACEDBDI_02608 1.1e-227 mleN C Na H antiporter
HACEDBDI_02609 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HACEDBDI_02610 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
HACEDBDI_02611 4.5e-58 ansR K Transcriptional regulator
HACEDBDI_02612 1.8e-220 yqxK 3.6.4.12 L DNA helicase
HACEDBDI_02613 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HACEDBDI_02615 1.2e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HACEDBDI_02616 3.1e-12 yqkE S Protein of unknown function (DUF3886)
HACEDBDI_02617 2.1e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HACEDBDI_02618 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HACEDBDI_02619 2.8e-54 yqkB S Belongs to the HesB IscA family
HACEDBDI_02620 9.8e-194 yqkA K GrpB protein
HACEDBDI_02621 2.6e-55 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HACEDBDI_02622 3.6e-87 yqjY K acetyltransferase
HACEDBDI_02623 5.7e-50 S YolD-like protein
HACEDBDI_02624 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HACEDBDI_02626 1.3e-224 yqjV G Major Facilitator Superfamily
HACEDBDI_02628 7.9e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HACEDBDI_02629 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HACEDBDI_02630 3.2e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HACEDBDI_02631 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HACEDBDI_02632 3.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HACEDBDI_02633 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HACEDBDI_02634 2.7e-271 rocB E arginine degradation protein
HACEDBDI_02635 2.9e-32 rocB E arginine degradation protein
HACEDBDI_02636 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HACEDBDI_02637 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HACEDBDI_02638 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HACEDBDI_02639 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HACEDBDI_02640 2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HACEDBDI_02641 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HACEDBDI_02642 1.1e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HACEDBDI_02643 4.5e-24 yqzJ
HACEDBDI_02644 1.5e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HACEDBDI_02645 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
HACEDBDI_02646 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HACEDBDI_02647 4.2e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HACEDBDI_02648 6.6e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HACEDBDI_02650 1.4e-98 yqjB S protein conserved in bacteria
HACEDBDI_02651 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
HACEDBDI_02652 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HACEDBDI_02653 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HACEDBDI_02654 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
HACEDBDI_02655 9.3e-77 yqiW S Belongs to the UPF0403 family
HACEDBDI_02656 1.2e-163 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HACEDBDI_02657 7.9e-208 norA EGP Major facilitator Superfamily
HACEDBDI_02658 1.3e-151 bmrR K helix_turn_helix, mercury resistance
HACEDBDI_02659 3.2e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HACEDBDI_02660 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HACEDBDI_02661 4.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HACEDBDI_02662 1.1e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HACEDBDI_02663 6e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HACEDBDI_02664 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HACEDBDI_02665 2.3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HACEDBDI_02666 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HACEDBDI_02667 4e-34 yqzF S Protein of unknown function (DUF2627)
HACEDBDI_02668 5.1e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HACEDBDI_02669 4.5e-274 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HACEDBDI_02670 4.9e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HACEDBDI_02671 1.3e-210 mmgC I acyl-CoA dehydrogenase
HACEDBDI_02672 1.3e-154 hbdA 1.1.1.157 I Dehydrogenase
HACEDBDI_02673 4e-153 mmgA 2.3.1.9 I Belongs to the thiolase family
HACEDBDI_02674 1.2e-53 mmgA 2.3.1.9 I Belongs to the thiolase family
HACEDBDI_02675 1.4e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HACEDBDI_02676 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HACEDBDI_02677 5.9e-27
HACEDBDI_02678 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HACEDBDI_02680 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HACEDBDI_02681 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HACEDBDI_02682 5.5e-306 recN L May be involved in recombinational repair of damaged DNA
HACEDBDI_02683 1.1e-77 argR K Regulates arginine biosynthesis genes
HACEDBDI_02684 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HACEDBDI_02685 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HACEDBDI_02686 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HACEDBDI_02687 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HACEDBDI_02688 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HACEDBDI_02689 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HACEDBDI_02690 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HACEDBDI_02691 2.1e-67 yqhY S protein conserved in bacteria
HACEDBDI_02692 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HACEDBDI_02693 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HACEDBDI_02694 9.9e-91 spoIIIAH S SpoIIIAH-like protein
HACEDBDI_02695 2.2e-109 spoIIIAG S stage III sporulation protein AG
HACEDBDI_02696 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HACEDBDI_02697 2.2e-197 spoIIIAE S stage III sporulation protein AE
HACEDBDI_02698 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HACEDBDI_02699 7.6e-29 spoIIIAC S stage III sporulation protein AC
HACEDBDI_02700 4.1e-84 spoIIIAB S Stage III sporulation protein
HACEDBDI_02701 4e-170 spoIIIAA S stage III sporulation protein AA
HACEDBDI_02702 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HACEDBDI_02703 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HACEDBDI_02704 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HACEDBDI_02705 9.4e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HACEDBDI_02706 2.3e-93 yqhR S Conserved membrane protein YqhR
HACEDBDI_02707 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
HACEDBDI_02708 2.2e-61 yqhP
HACEDBDI_02709 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
HACEDBDI_02710 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HACEDBDI_02711 7.5e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HACEDBDI_02712 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HACEDBDI_02713 5.3e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HACEDBDI_02714 7.1e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HACEDBDI_02715 3.7e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HACEDBDI_02716 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HACEDBDI_02717 1e-150 yqhG S Bacterial protein YqhG of unknown function
HACEDBDI_02718 3.6e-24 sinI S Anti-repressor SinI
HACEDBDI_02719 1e-54 sinR K transcriptional
HACEDBDI_02720 8.6e-142 tasA S Cell division protein FtsN
HACEDBDI_02721 6.7e-59 sipW 3.4.21.89 U Signal peptidase
HACEDBDI_02722 3.2e-109 yqxM
HACEDBDI_02723 2.6e-52 yqzG S Protein of unknown function (DUF3889)
HACEDBDI_02724 5.2e-26 yqzE S YqzE-like protein
HACEDBDI_02725 1.2e-43 S ComG operon protein 7
HACEDBDI_02726 4.1e-46 comGF U Putative Competence protein ComGF
HACEDBDI_02727 3.1e-59 comGE
HACEDBDI_02728 9.5e-66 gspH NU protein transport across the cell outer membrane
HACEDBDI_02729 1.4e-47 comGC U Required for transformation and DNA binding
HACEDBDI_02730 1.1e-173 comGB NU COG1459 Type II secretory pathway, component PulF
HACEDBDI_02731 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HACEDBDI_02732 1.4e-173 corA P Mg2 transporter protein
HACEDBDI_02733 2e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HACEDBDI_02734 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HACEDBDI_02736 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HACEDBDI_02737 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HACEDBDI_02738 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HACEDBDI_02739 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HACEDBDI_02740 6.9e-50 yqgV S Thiamine-binding protein
HACEDBDI_02741 1.8e-198 yqgU
HACEDBDI_02742 1.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HACEDBDI_02743 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HACEDBDI_02744 4.4e-180 glcK 2.7.1.2 G Glucokinase
HACEDBDI_02745 3.1e-33 yqgQ S Protein conserved in bacteria
HACEDBDI_02746 8.9e-236 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HACEDBDI_02747 2.5e-09 yqgO
HACEDBDI_02748 3.9e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HACEDBDI_02749 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HACEDBDI_02750 1.6e-194 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HACEDBDI_02752 9.2e-51 yqzD
HACEDBDI_02753 1.6e-71 yqzC S YceG-like family
HACEDBDI_02754 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HACEDBDI_02755 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HACEDBDI_02756 4.4e-158 pstA P Phosphate transport system permease
HACEDBDI_02757 9.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HACEDBDI_02758 7.6e-150 pstS P Phosphate
HACEDBDI_02759 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HACEDBDI_02760 2.5e-231 yqgE EGP Major facilitator superfamily
HACEDBDI_02761 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HACEDBDI_02762 4e-73 yqgC S protein conserved in bacteria
HACEDBDI_02763 3.9e-131 yqgB S Protein of unknown function (DUF1189)
HACEDBDI_02764 5.8e-46 yqfZ M LysM domain
HACEDBDI_02765 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HACEDBDI_02766 4.3e-62 yqfX S membrane
HACEDBDI_02767 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HACEDBDI_02768 2.1e-76 zur P Belongs to the Fur family
HACEDBDI_02769 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HACEDBDI_02770 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HACEDBDI_02771 1.2e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HACEDBDI_02772 6.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HACEDBDI_02773 3.5e-12 yqfQ S YqfQ-like protein
HACEDBDI_02774 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HACEDBDI_02775 1.1e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HACEDBDI_02776 1.4e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
HACEDBDI_02777 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HACEDBDI_02778 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HACEDBDI_02779 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HACEDBDI_02780 4.5e-88 yaiI S Belongs to the UPF0178 family
HACEDBDI_02781 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HACEDBDI_02782 4.5e-112 ccpN K CBS domain
HACEDBDI_02783 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HACEDBDI_02784 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HACEDBDI_02785 1.4e-144 recO L Involved in DNA repair and RecF pathway recombination
HACEDBDI_02786 8.4e-19 S YqzL-like protein
HACEDBDI_02787 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HACEDBDI_02788 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HACEDBDI_02789 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HACEDBDI_02790 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HACEDBDI_02791 0.0 yqfF S membrane-associated HD superfamily hydrolase
HACEDBDI_02793 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
HACEDBDI_02794 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HACEDBDI_02795 2.7e-45 yqfC S sporulation protein YqfC
HACEDBDI_02796 1e-24 yqfB
HACEDBDI_02797 4.3e-122 yqfA S UPF0365 protein
HACEDBDI_02798 2.6e-181 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HACEDBDI_02799 2.9e-30 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HACEDBDI_02800 2.5e-61 yqeY S Yqey-like protein
HACEDBDI_02801 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HACEDBDI_02802 4.1e-157 yqeW P COG1283 Na phosphate symporter
HACEDBDI_02803 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HACEDBDI_02804 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HACEDBDI_02805 3e-173 prmA J Methylates ribosomal protein L11
HACEDBDI_02806 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HACEDBDI_02807 0.0 dnaK O Heat shock 70 kDa protein
HACEDBDI_02808 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HACEDBDI_02809 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HACEDBDI_02810 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HACEDBDI_02811 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HACEDBDI_02812 1e-51 yqxA S Protein of unknown function (DUF3679)
HACEDBDI_02813 1.5e-222 spoIIP M stage II sporulation protein P
HACEDBDI_02814 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HACEDBDI_02815 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HACEDBDI_02816 4e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
HACEDBDI_02817 4.1e-15 S YqzM-like protein
HACEDBDI_02818 0.0 comEC S Competence protein ComEC
HACEDBDI_02819 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HACEDBDI_02820 3.9e-97 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HACEDBDI_02821 3.5e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HACEDBDI_02822 1.1e-138 yqeM Q Methyltransferase
HACEDBDI_02823 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HACEDBDI_02824 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HACEDBDI_02825 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HACEDBDI_02826 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HACEDBDI_02827 6.6e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HACEDBDI_02828 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HACEDBDI_02829 5.3e-95 yqeG S hydrolase of the HAD superfamily
HACEDBDI_02831 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HACEDBDI_02832 8.9e-136 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HACEDBDI_02833 2.6e-104 yqeD S SNARE associated Golgi protein
HACEDBDI_02834 4.7e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HACEDBDI_02835 2.8e-131 yqeB
HACEDBDI_02836 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HACEDBDI_02837 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACEDBDI_02838 3e-35 cisA2 L Recombinase
HACEDBDI_02839 2e-68 psiE S Protein PsiE homolog
HACEDBDI_02840 1.3e-235 yrkQ T Histidine kinase
HACEDBDI_02841 4.1e-127 T Transcriptional regulator
HACEDBDI_02842 1.5e-222 yrkO P Protein of unknown function (DUF418)
HACEDBDI_02843 2.3e-104 yrkN K Acetyltransferase (GNAT) family
HACEDBDI_02844 1.5e-97 ywrO S Flavodoxin-like fold
HACEDBDI_02845 2.8e-79 S Protein of unknown function with HXXEE motif
HACEDBDI_02846 1.4e-112 yrkJ S membrane transporter protein
HACEDBDI_02847 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HACEDBDI_02848 1.3e-207 yrkH P Rhodanese Homology Domain
HACEDBDI_02849 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
HACEDBDI_02850 2.8e-82 yrkE O DsrE/DsrF/DrsH-like family
HACEDBDI_02851 7.8e-39 yrkD S protein conserved in bacteria
HACEDBDI_02852 2.3e-21
HACEDBDI_02853 3.2e-106 yrkC G Cupin domain
HACEDBDI_02854 6.9e-150 bltR K helix_turn_helix, mercury resistance
HACEDBDI_02855 5.1e-210 blt EGP Major facilitator Superfamily
HACEDBDI_02856 9.1e-83 bltD 2.3.1.57 K FR47-like protein
HACEDBDI_02857 3.9e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HACEDBDI_02858 8.7e-16 S YrzO-like protein
HACEDBDI_02859 2.2e-60 yraO C Citrate transporter
HACEDBDI_02860 2.4e-52 yraO C Citrate transporter
HACEDBDI_02861 3.7e-162 yraN K Transcriptional regulator
HACEDBDI_02862 6.5e-204 yraM S PrpF protein
HACEDBDI_02863 1.4e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HACEDBDI_02864 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACEDBDI_02865 6e-154 S Alpha beta hydrolase
HACEDBDI_02866 1.7e-60 T sh3 domain protein
HACEDBDI_02867 2.4e-61 T sh3 domain protein
HACEDBDI_02869 3.6e-64 E Glyoxalase-like domain
HACEDBDI_02870 1.5e-36 yraG
HACEDBDI_02871 6.4e-63 yraF M Spore coat protein
HACEDBDI_02872 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HACEDBDI_02873 7.5e-26 yraE
HACEDBDI_02874 1.1e-49 yraD M Spore coat protein
HACEDBDI_02875 1.3e-46 yraB K helix_turn_helix, mercury resistance
HACEDBDI_02876 1.6e-28 yphJ 4.1.1.44 S peroxiredoxin activity
HACEDBDI_02877 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
HACEDBDI_02878 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HACEDBDI_02879 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HACEDBDI_02880 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HACEDBDI_02881 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HACEDBDI_02882 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HACEDBDI_02883 2.5e-74 levD 2.7.1.202 G PTS system fructose IIA component
HACEDBDI_02884 0.0 levR K PTS system fructose IIA component
HACEDBDI_02885 1.5e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HACEDBDI_02886 3.6e-106 yrhP E LysE type translocator
HACEDBDI_02887 5.3e-150 yrhO K Archaeal transcriptional regulator TrmB
HACEDBDI_02888 2.1e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HACEDBDI_02889 2.7e-149 rsiV S Protein of unknown function (DUF3298)
HACEDBDI_02890 0.0 yrhL I Acyltransferase family
HACEDBDI_02891 3.3e-46 yrhK S YrhK-like protein
HACEDBDI_02892 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HACEDBDI_02893 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HACEDBDI_02894 2.8e-91 yrhH Q methyltransferase
HACEDBDI_02897 6.7e-142 focA P Formate nitrite
HACEDBDI_02898 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
HACEDBDI_02899 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HACEDBDI_02900 2.4e-78 yrhD S Protein of unknown function (DUF1641)
HACEDBDI_02901 4.6e-35 yrhC S YrhC-like protein
HACEDBDI_02902 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HACEDBDI_02903 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HACEDBDI_02904 9.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HACEDBDI_02905 3.2e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HACEDBDI_02906 1e-25 yrzA S Protein of unknown function (DUF2536)
HACEDBDI_02907 1.6e-62 yrrS S Protein of unknown function (DUF1510)
HACEDBDI_02908 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HACEDBDI_02909 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HACEDBDI_02910 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HACEDBDI_02911 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HACEDBDI_02912 1.1e-172 yegQ O Peptidase U32
HACEDBDI_02913 1.5e-118 yrrM 2.1.1.104 S O-methyltransferase
HACEDBDI_02914 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HACEDBDI_02915 1.2e-45 yrzB S Belongs to the UPF0473 family
HACEDBDI_02916 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HACEDBDI_02917 1.7e-41 yrzL S Belongs to the UPF0297 family
HACEDBDI_02918 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HACEDBDI_02919 1.3e-169 yrrI S AI-2E family transporter
HACEDBDI_02920 6.4e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HACEDBDI_02921 4.8e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
HACEDBDI_02922 8e-109 gluC P ABC transporter
HACEDBDI_02923 7.6e-107 glnP P ABC transporter
HACEDBDI_02924 8e-08 S Protein of unknown function (DUF3918)
HACEDBDI_02925 9.8e-31 yrzR
HACEDBDI_02926 1.7e-81 yrrD S protein conserved in bacteria
HACEDBDI_02927 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HACEDBDI_02928 1.4e-15 S COG0457 FOG TPR repeat
HACEDBDI_02929 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HACEDBDI_02930 4.4e-211 iscS 2.8.1.7 E Cysteine desulfurase
HACEDBDI_02931 1.2e-70 cymR K Transcriptional regulator
HACEDBDI_02932 9.7e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HACEDBDI_02933 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HACEDBDI_02934 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HACEDBDI_02935 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HACEDBDI_02937 5.7e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
HACEDBDI_02938 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HACEDBDI_02939 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HACEDBDI_02940 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HACEDBDI_02941 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HACEDBDI_02942 1.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
HACEDBDI_02943 1.1e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HACEDBDI_02944 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HACEDBDI_02945 1.6e-48 yrzD S Post-transcriptional regulator
HACEDBDI_02946 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HACEDBDI_02947 1.3e-111 yrbG S membrane
HACEDBDI_02948 2.2e-73 yrzE S Protein of unknown function (DUF3792)
HACEDBDI_02949 8e-39 yajC U Preprotein translocase subunit YajC
HACEDBDI_02950 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HACEDBDI_02951 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HACEDBDI_02952 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HACEDBDI_02953 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HACEDBDI_02954 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HACEDBDI_02955 4.8e-93 bofC S BofC C-terminal domain
HACEDBDI_02956 4.5e-252 csbX EGP Major facilitator Superfamily
HACEDBDI_02957 1.8e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HACEDBDI_02958 1.9e-118 yrzF T serine threonine protein kinase
HACEDBDI_02960 2.3e-51 S Family of unknown function (DUF5412)
HACEDBDI_02961 1.5e-261 alsT E Sodium alanine symporter
HACEDBDI_02962 4.2e-127 yebC K transcriptional regulatory protein
HACEDBDI_02963 1.3e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HACEDBDI_02964 1.8e-156 safA M spore coat assembly protein SafA
HACEDBDI_02965 1.2e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HACEDBDI_02966 5.2e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HACEDBDI_02967 2.9e-301 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HACEDBDI_02968 4.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
HACEDBDI_02969 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
HACEDBDI_02970 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
HACEDBDI_02971 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HACEDBDI_02972 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HACEDBDI_02973 2.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HACEDBDI_02974 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HACEDBDI_02975 4.1e-56 ysxB J ribosomal protein
HACEDBDI_02976 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HACEDBDI_02977 9.2e-161 spoIVFB S Stage IV sporulation protein
HACEDBDI_02978 7.2e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HACEDBDI_02979 2.5e-144 minD D Belongs to the ParA family
HACEDBDI_02980 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HACEDBDI_02981 1.4e-84 mreD M shape-determining protein
HACEDBDI_02982 1.1e-156 mreC M Involved in formation and maintenance of cell shape
HACEDBDI_02983 1.8e-184 mreB D Rod shape-determining protein MreB
HACEDBDI_02984 6.5e-125 radC E Belongs to the UPF0758 family
HACEDBDI_02985 2.8e-102 maf D septum formation protein Maf
HACEDBDI_02986 6.4e-166 spoIIB S Sporulation related domain
HACEDBDI_02987 9.6e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HACEDBDI_02988 7.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HACEDBDI_02989 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HACEDBDI_02990 1.6e-25
HACEDBDI_02991 2.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HACEDBDI_02992 7.6e-191 spoVID M stage VI sporulation protein D
HACEDBDI_02993 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HACEDBDI_02994 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
HACEDBDI_02995 3.5e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HACEDBDI_02996 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HACEDBDI_02997 3.6e-146 hemX O cytochrome C
HACEDBDI_02998 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HACEDBDI_02999 5.4e-89 ysxD
HACEDBDI_03000 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HACEDBDI_03001 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HACEDBDI_03002 7.3e-308 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HACEDBDI_03003 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HACEDBDI_03004 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HACEDBDI_03005 1.1e-186 ysoA H Tetratricopeptide repeat
HACEDBDI_03006 9e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HACEDBDI_03007 8.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HACEDBDI_03008 1.8e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HACEDBDI_03009 1.7e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HACEDBDI_03010 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HACEDBDI_03011 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HACEDBDI_03012 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HACEDBDI_03014 3.5e-79 ysnE K acetyltransferase
HACEDBDI_03015 1.9e-159 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HACEDBDI_03016 1.7e-132 ysnF S protein conserved in bacteria
HACEDBDI_03018 4.1e-92 ysnB S Phosphoesterase
HACEDBDI_03019 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HACEDBDI_03020 2e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HACEDBDI_03021 9.4e-195 gerM S COG5401 Spore germination protein
HACEDBDI_03022 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HACEDBDI_03023 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HACEDBDI_03024 3.3e-30 gerE K Transcriptional regulator
HACEDBDI_03025 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HACEDBDI_03026 1.7e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HACEDBDI_03027 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HACEDBDI_03028 2.4e-107 sdhC C succinate dehydrogenase
HACEDBDI_03029 1.2e-79 yslB S Protein of unknown function (DUF2507)
HACEDBDI_03030 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HACEDBDI_03031 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HACEDBDI_03032 2e-52 trxA O Belongs to the thioredoxin family
HACEDBDI_03033 2.6e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HACEDBDI_03035 2.1e-177 etfA C Electron transfer flavoprotein
HACEDBDI_03036 4.5e-135 etfB C Electron transfer flavoprotein
HACEDBDI_03037 4.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HACEDBDI_03038 4e-99 fadR K Transcriptional regulator
HACEDBDI_03039 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HACEDBDI_03040 7.3e-68 yshE S membrane
HACEDBDI_03041 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HACEDBDI_03042 0.0 polX L COG1796 DNA polymerase IV (family X)
HACEDBDI_03043 3.9e-85 cvpA S membrane protein, required for colicin V production
HACEDBDI_03044 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HACEDBDI_03045 5.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HACEDBDI_03046 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HACEDBDI_03047 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HACEDBDI_03048 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HACEDBDI_03049 5.8e-32 sspI S Belongs to the SspI family
HACEDBDI_03050 1.5e-203 ysfB KT regulator
HACEDBDI_03051 3.3e-261 glcD 1.1.3.15 C Glycolate oxidase subunit
HACEDBDI_03052 5.8e-255 glcF C Glycolate oxidase
HACEDBDI_03053 1e-52 ysfE 4.4.1.5 E Glyoxalase-like domain
HACEDBDI_03054 0.0 cstA T Carbon starvation protein
HACEDBDI_03055 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HACEDBDI_03056 3.4e-144 araQ G transport system permease
HACEDBDI_03057 4.2e-167 araP G carbohydrate transport
HACEDBDI_03058 1.1e-253 araN G carbohydrate transport
HACEDBDI_03059 2.8e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HACEDBDI_03060 1.7e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HACEDBDI_03061 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HACEDBDI_03062 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HACEDBDI_03063 1.6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HACEDBDI_03064 1.5e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HACEDBDI_03065 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
HACEDBDI_03066 3.5e-67 ysdB S Sigma-w pathway protein YsdB
HACEDBDI_03067 7.5e-45 ysdA S Membrane
HACEDBDI_03068 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HACEDBDI_03069 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HACEDBDI_03070 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HACEDBDI_03072 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HACEDBDI_03073 3.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HACEDBDI_03074 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
HACEDBDI_03075 0.0 lytS 2.7.13.3 T Histidine kinase
HACEDBDI_03076 6.2e-148 ysaA S HAD-hyrolase-like
HACEDBDI_03077 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HACEDBDI_03079 1.4e-158 ytxC S YtxC-like family
HACEDBDI_03080 2.1e-109 ytxB S SNARE associated Golgi protein
HACEDBDI_03081 2.5e-172 dnaI L Primosomal protein DnaI
HACEDBDI_03082 7.7e-266 dnaB L Membrane attachment protein
HACEDBDI_03083 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HACEDBDI_03084 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HACEDBDI_03085 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HACEDBDI_03086 4.9e-66 ytcD K Transcriptional regulator
HACEDBDI_03087 1.6e-203 ytbD EGP Major facilitator Superfamily
HACEDBDI_03088 8.9e-161 ytbE S reductase
HACEDBDI_03089 1.3e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HACEDBDI_03090 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HACEDBDI_03091 7.8e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HACEDBDI_03092 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HACEDBDI_03093 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HACEDBDI_03094 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACEDBDI_03095 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HACEDBDI_03096 4.1e-242 icd 1.1.1.42 C isocitrate
HACEDBDI_03097 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HACEDBDI_03098 4.7e-71 yeaL S membrane
HACEDBDI_03099 4.4e-192 ytvI S sporulation integral membrane protein YtvI
HACEDBDI_03100 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HACEDBDI_03101 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HACEDBDI_03102 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HACEDBDI_03103 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HACEDBDI_03104 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HACEDBDI_03105 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HACEDBDI_03106 0.0 dnaE 2.7.7.7 L DNA polymerase
HACEDBDI_03107 3.2e-56 ytrH S Sporulation protein YtrH
HACEDBDI_03108 8.2e-69 ytrI
HACEDBDI_03109 9.2e-29
HACEDBDI_03110 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HACEDBDI_03111 2.4e-47 ytpI S YtpI-like protein
HACEDBDI_03112 8e-241 ytoI K transcriptional regulator containing CBS domains
HACEDBDI_03113 1.4e-156 ytnM S membrane transporter protein
HACEDBDI_03114 6e-76 ytnL 3.5.1.47 E hydrolase activity
HACEDBDI_03115 1.4e-117 ytnL 3.5.1.47 E hydrolase activity
HACEDBDI_03116 6.9e-127 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HACEDBDI_03117 4.1e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HACEDBDI_03118 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
HACEDBDI_03119 2.2e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HACEDBDI_03120 1.5e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HACEDBDI_03121 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
HACEDBDI_03122 7e-122 tcyL P Binding-protein-dependent transport system inner membrane component
HACEDBDI_03123 7.8e-146 tcyK M Bacterial periplasmic substrate-binding proteins
HACEDBDI_03124 2.2e-148 tcyK ET Bacterial periplasmic substrate-binding proteins
HACEDBDI_03125 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
HACEDBDI_03126 7.2e-172 ytlI K LysR substrate binding domain
HACEDBDI_03127 1.7e-130 ytkL S Belongs to the UPF0173 family
HACEDBDI_03128 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACEDBDI_03130 1.4e-264 argH 4.3.2.1 E argininosuccinate lyase
HACEDBDI_03131 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HACEDBDI_03132 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HACEDBDI_03133 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HACEDBDI_03134 2e-164 ytxK 2.1.1.72 L DNA methylase
HACEDBDI_03135 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HACEDBDI_03136 8.7e-70 ytfJ S Sporulation protein YtfJ
HACEDBDI_03137 8.1e-115 ytfI S Protein of unknown function (DUF2953)
HACEDBDI_03138 2.5e-86 yteJ S RDD family
HACEDBDI_03139 2.3e-179 sppA OU signal peptide peptidase SppA
HACEDBDI_03140 8.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HACEDBDI_03141 0.0 ytcJ S amidohydrolase
HACEDBDI_03142 2.9e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HACEDBDI_03143 2e-29 sspB S spore protein
HACEDBDI_03144 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HACEDBDI_03145 1e-207 iscS2 2.8.1.7 E Cysteine desulfurase
HACEDBDI_03146 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
HACEDBDI_03147 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HACEDBDI_03148 2.7e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HACEDBDI_03149 1e-108 yttP K Transcriptional regulator
HACEDBDI_03150 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HACEDBDI_03151 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HACEDBDI_03152 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HACEDBDI_03154 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HACEDBDI_03155 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HACEDBDI_03156 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HACEDBDI_03157 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HACEDBDI_03158 6.1e-224 acuC BQ histone deacetylase
HACEDBDI_03159 1.4e-125 motS N Flagellar motor protein
HACEDBDI_03160 2.1e-146 motA N flagellar motor
HACEDBDI_03161 1.7e-182 ccpA K catabolite control protein A
HACEDBDI_03162 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HACEDBDI_03163 7e-53 ytxJ O Protein of unknown function (DUF2847)
HACEDBDI_03164 6.6e-17 ytxH S COG4980 Gas vesicle protein
HACEDBDI_03165 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HACEDBDI_03166 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HACEDBDI_03167 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HACEDBDI_03168 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HACEDBDI_03169 9.8e-149 ytpQ S Belongs to the UPF0354 family
HACEDBDI_03170 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HACEDBDI_03171 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HACEDBDI_03172 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HACEDBDI_03173 6.3e-51 ytzB S small secreted protein
HACEDBDI_03174 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HACEDBDI_03175 7.1e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HACEDBDI_03176 2.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HACEDBDI_03177 2e-45 ytzH S YtzH-like protein
HACEDBDI_03178 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HACEDBDI_03179 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HACEDBDI_03180 7.2e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HACEDBDI_03181 1.3e-165 ytlQ
HACEDBDI_03182 8.9e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HACEDBDI_03183 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HACEDBDI_03184 2.7e-271 pepV 3.5.1.18 E Dipeptidase
HACEDBDI_03185 7.2e-226 pbuO S permease
HACEDBDI_03186 9.3e-201 ythQ U Bacterial ABC transporter protein EcsB
HACEDBDI_03187 4.8e-131 ythP V ABC transporter
HACEDBDI_03188 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HACEDBDI_03189 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HACEDBDI_03190 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HACEDBDI_03191 8.2e-232 ytfP S HI0933-like protein
HACEDBDI_03192 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HACEDBDI_03193 3.1e-26 yteV S Sporulation protein Cse60
HACEDBDI_03194 1.9e-113 yteU S Integral membrane protein
HACEDBDI_03195 5e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HACEDBDI_03196 5.6e-71 yteS G transport
HACEDBDI_03197 3.8e-220 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HACEDBDI_03198 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HACEDBDI_03199 0.0 ytdP K Transcriptional regulator
HACEDBDI_03200 4.9e-287 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HACEDBDI_03201 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
HACEDBDI_03202 3.6e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HACEDBDI_03203 3.1e-220 bioI 1.14.14.46 C Cytochrome P450
HACEDBDI_03204 2.9e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HACEDBDI_03205 1.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HACEDBDI_03206 1.6e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HACEDBDI_03207 1.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HACEDBDI_03208 2e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HACEDBDI_03209 9.2e-172 ytaP S Acetyl xylan esterase (AXE1)
HACEDBDI_03210 2.5e-189 msmR K Transcriptional regulator
HACEDBDI_03211 2.9e-243 msmE G Bacterial extracellular solute-binding protein
HACEDBDI_03212 6.2e-168 amyD P ABC transporter
HACEDBDI_03213 4.4e-144 amyC P ABC transporter (permease)
HACEDBDI_03214 8.4e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HACEDBDI_03215 2.1e-51 ytwF P Sulfurtransferase
HACEDBDI_03216 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HACEDBDI_03217 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HACEDBDI_03218 5.6e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HACEDBDI_03219 6e-211 yttB EGP Major facilitator Superfamily
HACEDBDI_03220 1.6e-41 yttA 2.7.13.3 S Pfam Transposase IS66
HACEDBDI_03221 0.0 bceB V ABC transporter (permease)
HACEDBDI_03222 1.1e-138 bceA V ABC transporter, ATP-binding protein
HACEDBDI_03223 4e-184 T PhoQ Sensor
HACEDBDI_03224 2.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACEDBDI_03225 2.1e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HACEDBDI_03226 9.1e-127 ytrE V ABC transporter, ATP-binding protein
HACEDBDI_03227 1e-128
HACEDBDI_03228 1.2e-151 P ABC-2 family transporter protein
HACEDBDI_03229 4.2e-161 ytrB P abc transporter atp-binding protein
HACEDBDI_03230 5.1e-66 ytrA K GntR family transcriptional regulator
HACEDBDI_03232 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HACEDBDI_03233 1.8e-189 yhcC S Fe-S oxidoreductase
HACEDBDI_03234 1.3e-105 ytqB J Putative rRNA methylase
HACEDBDI_03235 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HACEDBDI_03236 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HACEDBDI_03237 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HACEDBDI_03238 1.9e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HACEDBDI_03239 0.0 asnB 6.3.5.4 E Asparagine synthase
HACEDBDI_03240 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HACEDBDI_03241 2e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HACEDBDI_03242 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HACEDBDI_03243 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HACEDBDI_03244 1.8e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HACEDBDI_03245 1.4e-144 ytlC P ABC transporter
HACEDBDI_03246 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HACEDBDI_03247 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HACEDBDI_03248 7e-63 ytkC S Bacteriophage holin family
HACEDBDI_03249 2.1e-76 dps P Belongs to the Dps family
HACEDBDI_03251 1.1e-72 ytkA S YtkA-like
HACEDBDI_03252 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HACEDBDI_03253 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HACEDBDI_03254 3.6e-41 rpmE2 J Ribosomal protein L31
HACEDBDI_03255 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
HACEDBDI_03256 1.5e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HACEDBDI_03257 1.1e-24 S Domain of Unknown Function (DUF1540)
HACEDBDI_03258 1.2e-147 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HACEDBDI_03259 1.1e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HACEDBDI_03260 3.6e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HACEDBDI_03261 7.4e-169 troA P Belongs to the bacterial solute-binding protein 9 family
HACEDBDI_03262 9.2e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HACEDBDI_03263 1e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HACEDBDI_03264 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HACEDBDI_03265 1.1e-155 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HACEDBDI_03266 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HACEDBDI_03267 2.5e-272 menF 5.4.4.2 HQ Isochorismate synthase
HACEDBDI_03268 2.6e-132 dksA T COG1734 DnaK suppressor protein
HACEDBDI_03269 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
HACEDBDI_03270 1.9e-242 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HACEDBDI_03271 6.3e-179 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HACEDBDI_03272 1.7e-232 ytcC M Glycosyltransferase Family 4
HACEDBDI_03274 2.8e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
HACEDBDI_03275 4.5e-216 cotSA M Glycosyl transferases group 1
HACEDBDI_03276 2e-205 cotI S Spore coat protein
HACEDBDI_03277 2.2e-76 tspO T membrane
HACEDBDI_03278 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HACEDBDI_03279 8.4e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HACEDBDI_03280 4.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HACEDBDI_03281 2.3e-196 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HACEDBDI_03282 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HACEDBDI_03291 7.8e-08
HACEDBDI_03292 1.3e-09
HACEDBDI_03299 2e-08
HACEDBDI_03304 3.4e-39 S COG NOG14552 non supervised orthologous group
HACEDBDI_03305 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
HACEDBDI_03306 5.8e-94 M1-753 M FR47-like protein
HACEDBDI_03307 5.3e-188 yuaG 3.4.21.72 S protein conserved in bacteria
HACEDBDI_03308 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HACEDBDI_03309 3.9e-84 yuaE S DinB superfamily
HACEDBDI_03310 1.1e-106 yuaD
HACEDBDI_03311 3.2e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
HACEDBDI_03312 4e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HACEDBDI_03313 3.6e-94 yuaC K Belongs to the GbsR family
HACEDBDI_03314 3.1e-90 yuaB
HACEDBDI_03315 5.5e-121 ktrA P COG0569 K transport systems, NAD-binding component
HACEDBDI_03316 7.9e-236 ktrB P Potassium
HACEDBDI_03317 1e-38 yiaA S yiaA/B two helix domain
HACEDBDI_03318 1.1e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HACEDBDI_03319 2e-275 yubD P Major Facilitator Superfamily
HACEDBDI_03320 7.1e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HACEDBDI_03321 5.5e-45 S YolD-like protein
HACEDBDI_03322 2e-07 S Protein of unknown function (DUF3800)
HACEDBDI_03323 1.2e-27 K Helix-turn-helix domain
HACEDBDI_03325 9e-41 S protein domain associated with
HACEDBDI_03326 1.4e-102 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HACEDBDI_03327 1.3e-56 S Bacteriophage holin family
HACEDBDI_03328 2e-10 S Phage uncharacterised protein (Phage_XkdX)
HACEDBDI_03330 2.7e-33
HACEDBDI_03331 1.3e-60
HACEDBDI_03332 3e-106 Z012_12235 S homolog of phage Mu protein gp47
HACEDBDI_03333 4.8e-23 S Protein of unknown function (DUF2634)
HACEDBDI_03334 4.7e-23
HACEDBDI_03335 1e-88
HACEDBDI_03336 2.4e-30
HACEDBDI_03337 1e-40 3.5.1.28 M LysM domain
HACEDBDI_03338 4.1e-138 N phage tail tape measure protein
HACEDBDI_03339 3.6e-16
HACEDBDI_03340 1.8e-34
HACEDBDI_03341 1e-102 Z012_02110 S Protein of unknown function (DUF3383)
HACEDBDI_03342 7e-30
HACEDBDI_03343 4e-23
HACEDBDI_03344 3.6e-48
HACEDBDI_03345 2.4e-16 S Phage gp6-like head-tail connector protein
HACEDBDI_03346 1.3e-32 S Phage Mu protein F like protein
HACEDBDI_03348 1.9e-111 S Phage capsid family
HACEDBDI_03349 5.9e-63 S Domain of unknown function (DUF4355)
HACEDBDI_03351 9.8e-157 S Phage portal protein, SPP1 Gp6-like
HACEDBDI_03352 2.6e-185 ps334 S Terminase-like family
HACEDBDI_03353 7.8e-81 yqaS L DNA packaging
HACEDBDI_03357 8.9e-17 K Transcriptional regulator
HACEDBDI_03359 2.6e-70 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HACEDBDI_03363 5.3e-08 S YopX protein
HACEDBDI_03365 1.6e-106 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HACEDBDI_03367 6.9e-26
HACEDBDI_03369 1.7e-25 yqaO S Phage-like element PBSX protein XtrA
HACEDBDI_03371 1.3e-52 S Protein of unknown function (DUF1064)
HACEDBDI_03372 1.3e-07
HACEDBDI_03374 1.5e-80 xkdC L IstB-like ATP binding protein
HACEDBDI_03375 3.4e-25 L DnaD domain protein
HACEDBDI_03376 4.9e-135 recT L RecT family
HACEDBDI_03377 8.5e-152 yqaJ L YqaJ-like viral recombinase domain
HACEDBDI_03382 1.9e-82
HACEDBDI_03383 5.2e-67 S DNA binding
HACEDBDI_03384 5.8e-15 S Helix-turn-helix domain
HACEDBDI_03385 1.3e-16 K Helix-turn-helix XRE-family like proteins
HACEDBDI_03386 4e-18 xre K Helix-turn-helix XRE-family like proteins
HACEDBDI_03387 1.5e-49
HACEDBDI_03388 4.7e-23 S Protein of unknown function (DUF4064)
HACEDBDI_03389 2.5e-49 xkdA E IrrE N-terminal-like domain
HACEDBDI_03390 2.4e-167 L Belongs to the 'phage' integrase family
HACEDBDI_03392 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HACEDBDI_03393 9.1e-196 yubA S transporter activity
HACEDBDI_03394 6.3e-182 ygjR S Oxidoreductase
HACEDBDI_03395 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HACEDBDI_03396 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HACEDBDI_03397 5.1e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HACEDBDI_03398 6.6e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HACEDBDI_03399 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HACEDBDI_03401 2.1e-237 mcpA NT chemotaxis protein
HACEDBDI_03402 8.5e-295 mcpA NT chemotaxis protein
HACEDBDI_03403 1.1e-217 mcpA NT chemotaxis protein
HACEDBDI_03404 3.5e-224 mcpA NT chemotaxis protein
HACEDBDI_03405 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HACEDBDI_03406 1e-35
HACEDBDI_03407 3.1e-71 yugU S Uncharacterised protein family UPF0047
HACEDBDI_03408 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HACEDBDI_03409 3.2e-234 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HACEDBDI_03410 1.4e-116 yugP S Zn-dependent protease
HACEDBDI_03411 2.3e-38
HACEDBDI_03412 5.4e-53 mstX S Membrane-integrating protein Mistic
HACEDBDI_03413 2.2e-182 yugO P COG1226 Kef-type K transport systems
HACEDBDI_03414 1.3e-72 yugN S YugN-like family
HACEDBDI_03416 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HACEDBDI_03417 1.1e-228 yugK C Dehydrogenase
HACEDBDI_03418 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HACEDBDI_03419 1.1e-34 yuzA S Domain of unknown function (DUF378)
HACEDBDI_03420 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HACEDBDI_03421 2.1e-199 yugH 2.6.1.1 E Aminotransferase
HACEDBDI_03422 1.6e-85 alaR K Transcriptional regulator
HACEDBDI_03423 4.6e-154 yugF I Hydrolase
HACEDBDI_03424 1.1e-40 yugE S Domain of unknown function (DUF1871)
HACEDBDI_03425 7.6e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HACEDBDI_03426 2.1e-230 T PhoQ Sensor
HACEDBDI_03427 3.7e-69 kapB G Kinase associated protein B
HACEDBDI_03428 4.2e-115 kapD L the KinA pathway to sporulation
HACEDBDI_03430 2.1e-183 yuxJ EGP Major facilitator Superfamily
HACEDBDI_03431 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HACEDBDI_03432 1.8e-74 yuxK S protein conserved in bacteria
HACEDBDI_03433 6.3e-78 yufK S Family of unknown function (DUF5366)
HACEDBDI_03434 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HACEDBDI_03435 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HACEDBDI_03436 2.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HACEDBDI_03437 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HACEDBDI_03438 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HACEDBDI_03439 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HACEDBDI_03440 1.3e-233 maeN C COG3493 Na citrate symporter
HACEDBDI_03441 3.2e-14
HACEDBDI_03442 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HACEDBDI_03443 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HACEDBDI_03444 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HACEDBDI_03445 8.4e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HACEDBDI_03446 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HACEDBDI_03447 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HACEDBDI_03448 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HACEDBDI_03449 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
HACEDBDI_03450 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACEDBDI_03451 0.0 comP 2.7.13.3 T Histidine kinase
HACEDBDI_03453 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
HACEDBDI_03456 3.2e-22 yuzC
HACEDBDI_03457 1.8e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HACEDBDI_03458 8e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HACEDBDI_03459 1.2e-102 pncA Q COG1335 Amidases related to nicotinamidase
HACEDBDI_03460 5.1e-66 yueI S Protein of unknown function (DUF1694)
HACEDBDI_03461 7.4e-39 yueH S YueH-like protein
HACEDBDI_03462 6.6e-31 yueG S Spore germination protein gerPA/gerPF
HACEDBDI_03463 3.2e-190 yueF S transporter activity
HACEDBDI_03464 8.8e-71 S Protein of unknown function (DUF2283)
HACEDBDI_03465 2.9e-24 S Protein of unknown function (DUF2642)
HACEDBDI_03466 4.8e-96 yueE S phosphohydrolase
HACEDBDI_03467 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACEDBDI_03468 3.3e-64 yueC S Family of unknown function (DUF5383)
HACEDBDI_03469 0.0 esaA S type VII secretion protein EsaA
HACEDBDI_03470 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HACEDBDI_03471 5.7e-210 essB S WXG100 protein secretion system (Wss), protein YukC
HACEDBDI_03472 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HACEDBDI_03473 2.8e-45 esxA S Belongs to the WXG100 family
HACEDBDI_03474 4.7e-227 yukF QT Transcriptional regulator
HACEDBDI_03475 5.2e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HACEDBDI_03476 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HACEDBDI_03477 5e-36 mbtH S MbtH-like protein
HACEDBDI_03478 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACEDBDI_03479 1.2e-177 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HACEDBDI_03480 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HACEDBDI_03481 6.2e-224 entC 5.4.4.2 HQ Isochorismate synthase
HACEDBDI_03482 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HACEDBDI_03483 9.6e-166 besA S Putative esterase
HACEDBDI_03484 8.3e-121 yuiH S Oxidoreductase molybdopterin binding domain
HACEDBDI_03485 1.3e-92 bioY S Biotin biosynthesis protein
HACEDBDI_03486 8.7e-211 yuiF S antiporter
HACEDBDI_03487 2.5e-278 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HACEDBDI_03488 1.2e-77 yuiD S protein conserved in bacteria
HACEDBDI_03489 1.4e-116 yuiC S protein conserved in bacteria
HACEDBDI_03490 8.4e-27 yuiB S Putative membrane protein
HACEDBDI_03491 4.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
HACEDBDI_03492 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
HACEDBDI_03494 1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HACEDBDI_03495 1.9e-115 paiB K Putative FMN-binding domain
HACEDBDI_03496 2.3e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HACEDBDI_03497 3.7e-63 erpA S Belongs to the HesB IscA family
HACEDBDI_03498 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HACEDBDI_03499 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HACEDBDI_03500 3.2e-39 yuzB S Belongs to the UPF0349 family
HACEDBDI_03501 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HACEDBDI_03502 3e-56 yuzD S protein conserved in bacteria
HACEDBDI_03503 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HACEDBDI_03504 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HACEDBDI_03505 9.5e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HACEDBDI_03506 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HACEDBDI_03507 1e-240 hom 1.1.1.3 E homoserine dehydrogenase
HACEDBDI_03508 6.5e-198 yutH S Spore coat protein
HACEDBDI_03509 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HACEDBDI_03510 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HACEDBDI_03511 8.6e-75 yutE S Protein of unknown function DUF86
HACEDBDI_03512 9.7e-48 yutD S protein conserved in bacteria
HACEDBDI_03513 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HACEDBDI_03514 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HACEDBDI_03515 4.5e-196 lytH M Peptidase, M23
HACEDBDI_03516 3.9e-131 yunB S Sporulation protein YunB (Spo_YunB)
HACEDBDI_03517 4.8e-48 yunC S Domain of unknown function (DUF1805)
HACEDBDI_03518 1.6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HACEDBDI_03519 2e-141 yunE S membrane transporter protein
HACEDBDI_03520 4.3e-171 yunF S Protein of unknown function DUF72
HACEDBDI_03521 6.9e-59 yunG
HACEDBDI_03522 9.6e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HACEDBDI_03523 1.6e-299 pucR QT COG2508 Regulator of polyketide synthase expression
HACEDBDI_03524 2.2e-233 pbuX F Permease family
HACEDBDI_03525 1.8e-221 pbuX F xanthine
HACEDBDI_03526 3.7e-279 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HACEDBDI_03527 3.5e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HACEDBDI_03529 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HACEDBDI_03530 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HACEDBDI_03531 2.9e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HACEDBDI_03532 5.3e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HACEDBDI_03533 2.6e-183 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HACEDBDI_03534 1.6e-235 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HACEDBDI_03535 7.5e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HACEDBDI_03536 3.5e-168 bsn L Ribonuclease
HACEDBDI_03537 8.5e-204 msmX P Belongs to the ABC transporter superfamily
HACEDBDI_03538 3.3e-135 yurK K UTRA
HACEDBDI_03539 9.7e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HACEDBDI_03540 1.6e-168 yurM P COG0395 ABC-type sugar transport system, permease component
HACEDBDI_03541 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
HACEDBDI_03542 7.2e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HACEDBDI_03543 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HACEDBDI_03544 3.7e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HACEDBDI_03545 1.2e-205 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HACEDBDI_03547 1e-41
HACEDBDI_03548 4.2e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HACEDBDI_03549 3.5e-271 sufB O FeS cluster assembly
HACEDBDI_03550 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HACEDBDI_03551 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HACEDBDI_03552 4.5e-244 sufD O assembly protein SufD
HACEDBDI_03553 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HACEDBDI_03554 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HACEDBDI_03555 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
HACEDBDI_03556 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HACEDBDI_03557 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HACEDBDI_03558 2.4e-56 yusD S SCP-2 sterol transfer family
HACEDBDI_03559 1.2e-54 traF CO Thioredoxin
HACEDBDI_03560 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HACEDBDI_03561 1.1e-39 yusG S Protein of unknown function (DUF2553)
HACEDBDI_03562 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HACEDBDI_03563 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HACEDBDI_03564 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HACEDBDI_03565 6.1e-216 fadA 2.3.1.16 I Belongs to the thiolase family
HACEDBDI_03566 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HACEDBDI_03567 8.1e-09 S YuzL-like protein
HACEDBDI_03568 1.2e-163 fadM E Proline dehydrogenase
HACEDBDI_03569 5.1e-40
HACEDBDI_03570 5.4e-53 yusN M Coat F domain
HACEDBDI_03571 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
HACEDBDI_03572 1.2e-291 yusP P Major facilitator superfamily
HACEDBDI_03573 4.6e-64 yusQ S Tautomerase enzyme
HACEDBDI_03574 3.6e-105 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HACEDBDI_03575 5.7e-158 yusT K LysR substrate binding domain
HACEDBDI_03576 5.6e-39 yusU S Protein of unknown function (DUF2573)
HACEDBDI_03577 5.1e-153 yusV 3.6.3.34 HP ABC transporter
HACEDBDI_03578 2.5e-66 S YusW-like protein
HACEDBDI_03579 1.2e-300 pepF2 E COG1164 Oligoendopeptidase F
HACEDBDI_03580 1.5e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HACEDBDI_03581 1.8e-78 dps P Ferritin-like domain
HACEDBDI_03582 6.2e-236 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HACEDBDI_03583 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACEDBDI_03584 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
HACEDBDI_03585 4.3e-158 yuxN K Transcriptional regulator
HACEDBDI_03586 7.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HACEDBDI_03587 3.9e-24 S Protein of unknown function (DUF3970)
HACEDBDI_03588 2.6e-245 gerAA EG Spore germination protein
HACEDBDI_03589 3.8e-196 gerAB E Spore germination protein
HACEDBDI_03590 5e-183 gerAC S Spore germination B3/ GerAC like, C-terminal
HACEDBDI_03591 6.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACEDBDI_03592 1.6e-186 vraS 2.7.13.3 T Histidine kinase
HACEDBDI_03593 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HACEDBDI_03594 1.2e-123 liaG S Putative adhesin
HACEDBDI_03595 5.6e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HACEDBDI_03596 1.6e-61 liaI S membrane
HACEDBDI_03597 1.4e-226 yvqJ EGP Major facilitator Superfamily
HACEDBDI_03598 3.9e-99 yvqK 2.5.1.17 S Adenosyltransferase
HACEDBDI_03599 5.4e-245 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HACEDBDI_03600 1.7e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACEDBDI_03601 6.5e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HACEDBDI_03602 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HACEDBDI_03603 2.1e-128 yvrE G SMP-30/Gluconolaconase/LRE-like region
HACEDBDI_03604 0.0 T PhoQ Sensor
HACEDBDI_03605 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACEDBDI_03606 7.2e-23
HACEDBDI_03607 9.5e-98 yvrI K RNA polymerase
HACEDBDI_03608 2.4e-19 S YvrJ protein family
HACEDBDI_03609 4.7e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
HACEDBDI_03610 1.3e-64 yvrL S Regulatory protein YrvL
HACEDBDI_03611 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HACEDBDI_03612 3.5e-123 macB V ABC transporter, ATP-binding protein
HACEDBDI_03613 4.9e-173 M Efflux transporter rnd family, mfp subunit
HACEDBDI_03614 2.9e-148 fhuC 3.6.3.34 HP ABC transporter
HACEDBDI_03615 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACEDBDI_03616 1.1e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACEDBDI_03617 7.6e-177 fhuD P ABC transporter
HACEDBDI_03618 1.8e-235 yvsH E Arginine ornithine antiporter
HACEDBDI_03619 6.5e-16 S Small spore protein J (Spore_SspJ)
HACEDBDI_03620 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HACEDBDI_03621 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HACEDBDI_03622 2.4e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HACEDBDI_03623 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HACEDBDI_03624 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
HACEDBDI_03625 1.1e-155 yvgN S reductase
HACEDBDI_03626 2.1e-85 yvgO
HACEDBDI_03627 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HACEDBDI_03628 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HACEDBDI_03629 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HACEDBDI_03630 0.0 helD 3.6.4.12 L DNA helicase
HACEDBDI_03632 1.6e-106 yvgT S membrane
HACEDBDI_03633 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
HACEDBDI_03634 1.6e-104 bdbD O Thioredoxin
HACEDBDI_03635 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HACEDBDI_03636 0.0 copA 3.6.3.54 P P-type ATPase
HACEDBDI_03637 5.9e-29 copZ P Copper resistance protein CopZ
HACEDBDI_03638 2.2e-48 csoR S transcriptional
HACEDBDI_03639 6.9e-195 yvaA 1.1.1.371 S Oxidoreductase
HACEDBDI_03640 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HACEDBDI_03641 0.0 yvaC S Fusaric acid resistance protein-like
HACEDBDI_03642 9.7e-73 yvaD S Family of unknown function (DUF5360)
HACEDBDI_03643 1.8e-54 yvaE P Small Multidrug Resistance protein
HACEDBDI_03644 8.6e-99 K Bacterial regulatory proteins, tetR family
HACEDBDI_03645 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HACEDBDI_03646 5.3e-15
HACEDBDI_03649 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HACEDBDI_03650 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HACEDBDI_03651 5.6e-143 est 3.1.1.1 S Carboxylesterase
HACEDBDI_03652 2.4e-23 secG U Preprotein translocase subunit SecG
HACEDBDI_03653 5.9e-151 yvaM S Serine aminopeptidase, S33
HACEDBDI_03654 9.8e-36 yvzC K Transcriptional
HACEDBDI_03655 4e-69 K transcriptional
HACEDBDI_03656 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
HACEDBDI_03657 2.2e-54 yodB K transcriptional
HACEDBDI_03658 4.2e-218 NT chemotaxis protein
HACEDBDI_03659 8.7e-153 T His Kinase A (phosphoacceptor) domain
HACEDBDI_03660 2.5e-105 K Transcriptional regulatory protein, C terminal
HACEDBDI_03661 1.7e-81 mutG S ABC-2 family transporter protein
HACEDBDI_03662 1.5e-87 spaE S ABC-2 family transporter protein
HACEDBDI_03663 4.2e-103 mutF V ABC transporter, ATP-binding protein
HACEDBDI_03665 1.1e-09 S Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
HACEDBDI_03666 2.1e-95 spaC2 V PFAM Lanthionine synthetase
HACEDBDI_03667 1.3e-156 spaT V ABC transporter
HACEDBDI_03668 5.3e-195 spaB S Lantibiotic dehydratase, C terminus
HACEDBDI_03669 1.4e-103 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HACEDBDI_03670 1e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HACEDBDI_03671 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HACEDBDI_03672 6.3e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HACEDBDI_03673 3.3e-60 yvbF K Belongs to the GbsR family
HACEDBDI_03674 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HACEDBDI_03675 2.7e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HACEDBDI_03676 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HACEDBDI_03677 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HACEDBDI_03678 1.3e-96 yvbF K Belongs to the GbsR family
HACEDBDI_03679 6.4e-103 yvbG U UPF0056 membrane protein
HACEDBDI_03680 1.9e-112 yvbH S YvbH-like oligomerisation region
HACEDBDI_03681 2.3e-122 exoY M Membrane
HACEDBDI_03682 0.0 tcaA S response to antibiotic
HACEDBDI_03683 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
HACEDBDI_03684 1.3e-173 EGP Major facilitator Superfamily
HACEDBDI_03685 3.7e-152
HACEDBDI_03686 1.5e-113 S GlcNAc-PI de-N-acetylase
HACEDBDI_03687 9.2e-122 C WbqC-like protein family
HACEDBDI_03688 4.5e-114 M Protein involved in cellulose biosynthesis
HACEDBDI_03689 7.9e-158 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HACEDBDI_03690 2.1e-147 5.1.3.2 M GDP-mannose 4,6 dehydratase
HACEDBDI_03691 5.7e-187 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HACEDBDI_03692 2.8e-217 1.1.1.136 M UDP binding domain
HACEDBDI_03693 6.9e-165 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HACEDBDI_03694 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HACEDBDI_03695 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HACEDBDI_03696 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HACEDBDI_03697 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HACEDBDI_03698 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HACEDBDI_03699 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HACEDBDI_03700 1.6e-252 araE EGP Major facilitator Superfamily
HACEDBDI_03701 5.5e-203 araR K transcriptional
HACEDBDI_03702 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HACEDBDI_03703 5.1e-159 yvbU K Transcriptional regulator
HACEDBDI_03704 7.2e-156 yvbV EG EamA-like transporter family
HACEDBDI_03705 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HACEDBDI_03706 1.9e-184 yvbX S Glycosyl hydrolase
HACEDBDI_03707 7.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HACEDBDI_03708 4.6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HACEDBDI_03709 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HACEDBDI_03710 1.3e-44 S Protein of unknown function (DUF2812)
HACEDBDI_03711 2.6e-31 K Transcriptional regulator PadR-like family
HACEDBDI_03712 6.5e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACEDBDI_03713 2.4e-193 desK 2.7.13.3 T Histidine kinase
HACEDBDI_03714 4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
HACEDBDI_03715 4.4e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HACEDBDI_03717 6.4e-156 rsbQ S Alpha/beta hydrolase family
HACEDBDI_03718 1.8e-199 rsbU 3.1.3.3 T response regulator
HACEDBDI_03719 1.9e-250 galA 3.2.1.89 G arabinogalactan
HACEDBDI_03720 0.0 lacA 3.2.1.23 G beta-galactosidase
HACEDBDI_03721 7.2e-150 ganQ P transport
HACEDBDI_03722 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
HACEDBDI_03723 1e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
HACEDBDI_03724 2e-183 lacR K Transcriptional regulator
HACEDBDI_03725 2.3e-112 yvfI K COG2186 Transcriptional regulators
HACEDBDI_03726 2.4e-306 yvfH C L-lactate permease
HACEDBDI_03727 1.2e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HACEDBDI_03728 1e-31 yvfG S YvfG protein
HACEDBDI_03729 2.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
HACEDBDI_03730 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HACEDBDI_03731 9e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HACEDBDI_03732 1.2e-106 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HACEDBDI_03733 8.3e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HACEDBDI_03734 1e-190 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HACEDBDI_03735 1.2e-202 epsI GM pyruvyl transferase
HACEDBDI_03736 2e-194 epsH GT2 S Glycosyltransferase like family 2
HACEDBDI_03737 1.8e-206 epsG S EpsG family
HACEDBDI_03738 8.4e-218 epsF GT4 M Glycosyl transferases group 1
HACEDBDI_03739 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HACEDBDI_03740 1.5e-222 epsD GT4 M Glycosyl transferase 4-like
HACEDBDI_03741 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HACEDBDI_03742 2.3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HACEDBDI_03743 4e-122 ywqC M biosynthesis protein
HACEDBDI_03744 6.3e-76 slr K transcriptional
HACEDBDI_03745 2.4e-286 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HACEDBDI_03747 5.1e-92 padC Q Phenolic acid decarboxylase
HACEDBDI_03748 3.8e-73 MA20_18690 S Protein of unknown function (DUF3237)
HACEDBDI_03749 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HACEDBDI_03750 9.3e-261 pbpE V Beta-lactamase
HACEDBDI_03751 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HACEDBDI_03752 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HACEDBDI_03753 1.8e-295 yveA E amino acid
HACEDBDI_03754 7.4e-106 yvdT K Transcriptional regulator
HACEDBDI_03755 4.3e-50 ykkC P Small Multidrug Resistance protein
HACEDBDI_03756 4.1e-50 sugE P Small Multidrug Resistance protein
HACEDBDI_03757 5.4e-92 yvdQ S Protein of unknown function (DUF3231)
HACEDBDI_03759 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HACEDBDI_03760 1.3e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HACEDBDI_03761 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HACEDBDI_03762 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HACEDBDI_03763 5e-154 malA S Protein of unknown function (DUF1189)
HACEDBDI_03764 8.6e-148 malD P transport
HACEDBDI_03765 5e-243 malC P COG1175 ABC-type sugar transport systems, permease components
HACEDBDI_03766 6.9e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HACEDBDI_03767 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HACEDBDI_03768 1.1e-172 yvdE K Transcriptional regulator
HACEDBDI_03769 4.7e-105 yvdD 3.2.2.10 S Belongs to the LOG family
HACEDBDI_03770 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HACEDBDI_03771 8.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HACEDBDI_03772 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HACEDBDI_03773 5.6e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HACEDBDI_03774 0.0 yxdM V ABC transporter (permease)
HACEDBDI_03775 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HACEDBDI_03776 3.2e-195 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HACEDBDI_03777 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACEDBDI_03778 9.7e-32
HACEDBDI_03779 9.5e-146 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HACEDBDI_03780 1.6e-36 crh G Phosphocarrier protein Chr
HACEDBDI_03781 1.4e-170 whiA K May be required for sporulation
HACEDBDI_03782 1.4e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HACEDBDI_03783 1.7e-165 rapZ S Displays ATPase and GTPase activities
HACEDBDI_03784 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HACEDBDI_03785 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HACEDBDI_03786 2.3e-97 usp CBM50 M protein conserved in bacteria
HACEDBDI_03787 7.6e-277 S COG0457 FOG TPR repeat
HACEDBDI_03788 0.0 msbA2 3.6.3.44 V ABC transporter
HACEDBDI_03790 5e-252
HACEDBDI_03791 1.1e-69
HACEDBDI_03792 1.4e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HACEDBDI_03793 3.4e-135 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HACEDBDI_03794 3.2e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HACEDBDI_03795 2.8e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HACEDBDI_03796 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HACEDBDI_03797 1.7e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HACEDBDI_03798 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HACEDBDI_03799 1.2e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HACEDBDI_03800 1e-139 yvpB NU protein conserved in bacteria
HACEDBDI_03801 1.3e-117 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HACEDBDI_03802 9.6e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HACEDBDI_03803 4.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HACEDBDI_03804 3.4e-161 yvoD P COG0370 Fe2 transport system protein B
HACEDBDI_03805 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HACEDBDI_03806 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HACEDBDI_03807 1.5e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HACEDBDI_03808 1.2e-126 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HACEDBDI_03809 1.8e-133 yvoA K transcriptional
HACEDBDI_03810 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HACEDBDI_03811 1.2e-50 yvlD S Membrane
HACEDBDI_03812 2.6e-26 pspB KT PspC domain
HACEDBDI_03813 1.2e-165 yvlB S Putative adhesin
HACEDBDI_03814 1.8e-48 yvlA
HACEDBDI_03815 5.7e-33 yvkN
HACEDBDI_03816 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HACEDBDI_03817 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HACEDBDI_03818 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HACEDBDI_03819 1.2e-30 csbA S protein conserved in bacteria
HACEDBDI_03820 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HACEDBDI_03821 7e-101 yvkB K Transcriptional regulator
HACEDBDI_03822 2.8e-225 yvkA EGP Major facilitator Superfamily
HACEDBDI_03823 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HACEDBDI_03824 5.3e-56 swrA S Swarming motility protein
HACEDBDI_03825 5.8e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HACEDBDI_03826 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HACEDBDI_03827 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HACEDBDI_03828 3.8e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
HACEDBDI_03829 9.3e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HACEDBDI_03830 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HACEDBDI_03831 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HACEDBDI_03832 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HACEDBDI_03833 1.8e-65
HACEDBDI_03834 1.9e-08 fliT S bacterial-type flagellum organization
HACEDBDI_03835 2.9e-69 fliS N flagellar protein FliS
HACEDBDI_03836 5.3e-249 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HACEDBDI_03837 6.1e-57 flaG N flagellar protein FlaG
HACEDBDI_03838 5.9e-93 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HACEDBDI_03839 9.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HACEDBDI_03840 6.1e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HACEDBDI_03841 5.7e-50 yviE
HACEDBDI_03842 7.8e-155 flgL N Belongs to the bacterial flagellin family
HACEDBDI_03843 1.2e-264 flgK N flagellar hook-associated protein
HACEDBDI_03844 9.2e-78 flgN NOU FlgN protein
HACEDBDI_03845 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
HACEDBDI_03846 7e-74 yvyF S flagellar protein
HACEDBDI_03847 4.7e-126 comFC S Phosphoribosyl transferase domain
HACEDBDI_03848 3.7e-45 comFB S Late competence development protein ComFB
HACEDBDI_03849 7.6e-266 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HACEDBDI_03850 2.1e-154 degV S protein conserved in bacteria
HACEDBDI_03851 5.8e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACEDBDI_03852 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HACEDBDI_03853 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HACEDBDI_03854 6e-163 yvhJ K Transcriptional regulator
HACEDBDI_03855 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HACEDBDI_03856 6.2e-232 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HACEDBDI_03857 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HACEDBDI_03858 5.1e-114 tuaF M protein involved in exopolysaccharide biosynthesis
HACEDBDI_03859 3.7e-263 tuaE M Teichuronic acid biosynthesis protein
HACEDBDI_03860 1.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HACEDBDI_03861 2e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HACEDBDI_03862 5.7e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HACEDBDI_03863 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HACEDBDI_03864 1.4e-151 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HACEDBDI_03865 2.8e-48 lytB 3.5.1.28 D Stage II sporulation protein
HACEDBDI_03866 7.3e-36
HACEDBDI_03867 1.8e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HACEDBDI_03868 2.2e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HACEDBDI_03870 5.3e-119 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HACEDBDI_03871 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HACEDBDI_03872 2.9e-269 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HACEDBDI_03873 2.7e-133 tagG GM Transport permease protein
HACEDBDI_03874 1.1e-52 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HACEDBDI_03875 5.4e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HACEDBDI_03876 9.2e-96 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HACEDBDI_03877 2e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HACEDBDI_03878 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HACEDBDI_03879 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HACEDBDI_03880 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HACEDBDI_03881 5.6e-54 3.4.11.5 S alpha beta
HACEDBDI_03882 3.5e-129 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HACEDBDI_03883 3.9e-160 wecC 1.1.1.336 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HACEDBDI_03884 1.8e-126 M DUF based on E. rectale Gene description (DUF3880)
HACEDBDI_03886 9.5e-159 wbmJ M Glycosyl transferases group 1
HACEDBDI_03887 2.4e-127 M Glycosyl transferase group 1 protein
HACEDBDI_03888 4.4e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HACEDBDI_03889 1.5e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HACEDBDI_03890 1.2e-261 gerBA EG Spore germination protein
HACEDBDI_03891 1.5e-192 gerBB E Spore germination protein
HACEDBDI_03892 3.2e-206 gerAC S Spore germination protein
HACEDBDI_03893 1.3e-246 ywtG EGP Major facilitator Superfamily
HACEDBDI_03894 1.9e-138 ywtF K Transcriptional regulator
HACEDBDI_03895 2.1e-157 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HACEDBDI_03896 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HACEDBDI_03897 3.6e-21 ywtC
HACEDBDI_03898 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HACEDBDI_03899 8.6e-70 pgsC S biosynthesis protein
HACEDBDI_03900 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HACEDBDI_03901 5.5e-178 rbsR K transcriptional
HACEDBDI_03902 8.4e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HACEDBDI_03903 1.1e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HACEDBDI_03904 3.3e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HACEDBDI_03905 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HACEDBDI_03906 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HACEDBDI_03907 7.3e-92 batE T Sh3 type 3 domain protein
HACEDBDI_03908 8e-48 ywsA S Protein of unknown function (DUF3892)
HACEDBDI_03909 2.4e-95 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HACEDBDI_03910 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HACEDBDI_03911 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HACEDBDI_03912 1.1e-169 alsR K LysR substrate binding domain
HACEDBDI_03913 1.8e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HACEDBDI_03914 1.1e-124 ywrJ
HACEDBDI_03915 4.6e-125 cotB
HACEDBDI_03916 6.2e-207 cotH M Spore Coat
HACEDBDI_03917 1.3e-12
HACEDBDI_03918 9e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HACEDBDI_03919 3.6e-52 S Domain of unknown function (DUF4181)
HACEDBDI_03920 6.1e-304 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HACEDBDI_03921 8e-82 ywrC K Transcriptional regulator
HACEDBDI_03922 1.6e-103 ywrB P Chromate transporter
HACEDBDI_03923 1.3e-88 ywrA P COG2059 Chromate transport protein ChrA
HACEDBDI_03925 4.3e-132 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HACEDBDI_03926 1.7e-52 S MORN repeat variant
HACEDBDI_03927 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
HACEDBDI_03928 3.9e-38 ywqI S Family of unknown function (DUF5344)
HACEDBDI_03929 9.7e-23 S Domain of unknown function (DUF5082)
HACEDBDI_03930 2.4e-152 ywqG S Domain of unknown function (DUF1963)
HACEDBDI_03931 7.5e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HACEDBDI_03932 2.5e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HACEDBDI_03933 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HACEDBDI_03934 2.3e-115 ywqC M biosynthesis protein
HACEDBDI_03935 1.2e-17
HACEDBDI_03936 1.4e-308 ywqB S SWIM zinc finger
HACEDBDI_03937 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HACEDBDI_03938 1.1e-153 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HACEDBDI_03939 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HACEDBDI_03940 3.7e-57 ssbB L Single-stranded DNA-binding protein
HACEDBDI_03941 1.3e-66 ywpG
HACEDBDI_03942 1.1e-66 ywpF S YwpF-like protein
HACEDBDI_03943 2.6e-49 srtA 3.4.22.70 M Sortase family
HACEDBDI_03944 1e-39 ywpD T PhoQ Sensor
HACEDBDI_03945 1.4e-51 ywpD T Histidine kinase
HACEDBDI_03946 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HACEDBDI_03947 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HACEDBDI_03948 2.1e-199 S aspartate phosphatase
HACEDBDI_03949 1.5e-141 flhP N flagellar basal body
HACEDBDI_03950 5.8e-125 flhO N flagellar basal body
HACEDBDI_03951 3.5e-180 mbl D Rod shape-determining protein
HACEDBDI_03952 3e-44 spoIIID K Stage III sporulation protein D
HACEDBDI_03953 2.1e-70 ywoH K COG1846 Transcriptional regulators
HACEDBDI_03954 2.7e-211 ywoG EGP Major facilitator Superfamily
HACEDBDI_03955 9.8e-229 ywoF P Right handed beta helix region
HACEDBDI_03956 3.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HACEDBDI_03957 2.4e-240 ywoD EGP Major facilitator superfamily
HACEDBDI_03958 2e-103 phzA Q Isochorismatase family
HACEDBDI_03959 8.3e-76
HACEDBDI_03960 4.3e-225 amt P Ammonium transporter
HACEDBDI_03961 1.6e-58 nrgB K Belongs to the P(II) protein family
HACEDBDI_03962 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HACEDBDI_03963 6.6e-72 ywnJ S VanZ like family
HACEDBDI_03964 6.9e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HACEDBDI_03965 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HACEDBDI_03966 3.9e-08 ywnC S Family of unknown function (DUF5362)
HACEDBDI_03967 1.9e-189 spsF 2.5.1.56, 2.7.7.92 M NeuB family
HACEDBDI_03968 2.2e-70 ywnF S Family of unknown function (DUF5392)
HACEDBDI_03969 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HACEDBDI_03970 5e-142 mta K transcriptional
HACEDBDI_03971 2.6e-59 ywnC S Family of unknown function (DUF5362)
HACEDBDI_03972 1.3e-111 ywnB S NAD(P)H-binding
HACEDBDI_03973 1.7e-64 ywnA K Transcriptional regulator
HACEDBDI_03974 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HACEDBDI_03975 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HACEDBDI_03976 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HACEDBDI_03977 5.8e-17 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HACEDBDI_03978 3.8e-11 csbD K CsbD-like
HACEDBDI_03979 3e-84 ywmF S Peptidase M50
HACEDBDI_03980 6.1e-104 S response regulator aspartate phosphatase
HACEDBDI_03981 5e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HACEDBDI_03982 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HACEDBDI_03984 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HACEDBDI_03985 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HACEDBDI_03986 7.8e-175 spoIID D Stage II sporulation protein D
HACEDBDI_03987 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HACEDBDI_03988 2.4e-133 ywmB S TATA-box binding
HACEDBDI_03989 1.3e-32 ywzB S membrane
HACEDBDI_03990 1.8e-86 ywmA
HACEDBDI_03991 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HACEDBDI_03992 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HACEDBDI_03993 2.5e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HACEDBDI_03994 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HACEDBDI_03995 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HACEDBDI_03996 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HACEDBDI_03997 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HACEDBDI_03998 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HACEDBDI_03999 2.5e-62 atpI S ATP synthase
HACEDBDI_04000 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HACEDBDI_04001 4.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HACEDBDI_04002 3.6e-94 ywlG S Belongs to the UPF0340 family
HACEDBDI_04003 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HACEDBDI_04004 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HACEDBDI_04005 1.7e-91 mntP P Probably functions as a manganese efflux pump
HACEDBDI_04006 8.1e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HACEDBDI_04007 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HACEDBDI_04008 6.1e-112 spoIIR S stage II sporulation protein R
HACEDBDI_04009 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
HACEDBDI_04011 2.5e-158 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HACEDBDI_04012 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HACEDBDI_04013 2.6e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HACEDBDI_04014 7.8e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HACEDBDI_04015 8.6e-160 ywkB S Membrane transport protein
HACEDBDI_04016 0.0 sfcA 1.1.1.38 C malic enzyme
HACEDBDI_04017 7e-104 tdk 2.7.1.21 F thymidine kinase
HACEDBDI_04018 1.1e-32 rpmE J Binds the 23S rRNA
HACEDBDI_04019 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HACEDBDI_04020 1.1e-173 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HACEDBDI_04021 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HACEDBDI_04022 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HACEDBDI_04023 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HACEDBDI_04024 4.2e-62 spo0F T COG0784 FOG CheY-like receiver
HACEDBDI_04025 1.8e-90 ywjG S Domain of unknown function (DUF2529)
HACEDBDI_04026 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HACEDBDI_04027 1.1e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HACEDBDI_04028 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HACEDBDI_04029 0.0 fadF C COG0247 Fe-S oxidoreductase
HACEDBDI_04030 3.2e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HACEDBDI_04031 9.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HACEDBDI_04032 2.7e-42 ywjC
HACEDBDI_04033 4.5e-94 ywjB H RibD C-terminal domain
HACEDBDI_04034 0.0 ywjA V ABC transporter
HACEDBDI_04035 2.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HACEDBDI_04036 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
HACEDBDI_04037 3.6e-94 narJ 1.7.5.1 C nitrate reductase
HACEDBDI_04038 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
HACEDBDI_04039 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HACEDBDI_04040 2e-85 arfM T cyclic nucleotide binding
HACEDBDI_04041 1.7e-139 ywiC S YwiC-like protein
HACEDBDI_04042 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
HACEDBDI_04043 1e-213 narK P COG2223 Nitrate nitrite transporter
HACEDBDI_04044 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HACEDBDI_04045 4.7e-73 ywiB S protein conserved in bacteria
HACEDBDI_04046 1e-07 S Bacteriocin subtilosin A
HACEDBDI_04047 4.9e-270 C Fe-S oxidoreductases
HACEDBDI_04049 3.3e-132 cbiO V ABC transporter
HACEDBDI_04050 4.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HACEDBDI_04051 1.2e-214 2.7.1.26, 2.7.7.2 L Peptidase, M16
HACEDBDI_04052 2.3e-245 L Peptidase, M16
HACEDBDI_04054 6.2e-244 ywhL CO amine dehydrogenase activity
HACEDBDI_04055 3e-190 ywhK CO amine dehydrogenase activity
HACEDBDI_04056 4.4e-78 S aspartate phosphatase
HACEDBDI_04058 1.2e-49 ywhH S Aminoacyl-tRNA editing domain
HACEDBDI_04059 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HACEDBDI_04060 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HACEDBDI_04061 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HACEDBDI_04062 3.6e-49
HACEDBDI_04063 5.2e-95 ywhD S YwhD family
HACEDBDI_04064 3.3e-118 ywhC S Peptidase family M50
HACEDBDI_04065 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HACEDBDI_04066 3.3e-71 ywhA K Transcriptional regulator
HACEDBDI_04067 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HACEDBDI_04069 1.3e-236 mmr U Major Facilitator Superfamily
HACEDBDI_04070 6.2e-79 yffB K Transcriptional regulator
HACEDBDI_04071 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HACEDBDI_04072 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
HACEDBDI_04073 3.1e-36 ywzC S Belongs to the UPF0741 family
HACEDBDI_04074 5.1e-110 rsfA_1
HACEDBDI_04075 3.5e-155 ywfM EG EamA-like transporter family
HACEDBDI_04076 2.1e-154 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HACEDBDI_04077 1.1e-156 cysL K Transcriptional regulator
HACEDBDI_04078 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HACEDBDI_04079 1.1e-146 ywfI C May function as heme-dependent peroxidase
HACEDBDI_04080 1.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
HACEDBDI_04081 5e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
HACEDBDI_04082 1.9e-209 bacE EGP Major facilitator Superfamily
HACEDBDI_04083 4.7e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HACEDBDI_04084 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACEDBDI_04085 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HACEDBDI_04086 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HACEDBDI_04087 6e-206 ywfA EGP Major facilitator Superfamily
HACEDBDI_04088 1.7e-249 lysP E amino acid
HACEDBDI_04089 0.0 rocB E arginine degradation protein
HACEDBDI_04090 3.5e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HACEDBDI_04091 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HACEDBDI_04092 9.8e-77
HACEDBDI_04093 6.7e-86 spsL 5.1.3.13 M Spore Coat
HACEDBDI_04094 3.5e-157 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HACEDBDI_04095 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HACEDBDI_04096 4.6e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HACEDBDI_04097 1.6e-188 spsG M Spore Coat
HACEDBDI_04098 3.5e-129 spsF M Spore Coat
HACEDBDI_04099 1.6e-213 spsE 2.5.1.56 M acid synthase
HACEDBDI_04100 8.9e-164 spsD 2.3.1.210 K Spore Coat
HACEDBDI_04101 2.1e-224 spsC E Belongs to the DegT DnrJ EryC1 family
HACEDBDI_04102 1e-267 spsB M Capsule polysaccharide biosynthesis protein
HACEDBDI_04103 2.4e-144 spsA M Spore Coat
HACEDBDI_04104 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HACEDBDI_04105 4.3e-59 ywdK S small membrane protein
HACEDBDI_04106 3.7e-238 ywdJ F Xanthine uracil
HACEDBDI_04107 5e-48 ywdI S Family of unknown function (DUF5327)
HACEDBDI_04108 7.2e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HACEDBDI_04109 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HACEDBDI_04110 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HACEDBDI_04112 1.4e-113 ywdD
HACEDBDI_04113 1.3e-57 pex K Transcriptional regulator PadR-like family
HACEDBDI_04114 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HACEDBDI_04115 2e-28 ywdA
HACEDBDI_04116 1.1e-291 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HACEDBDI_04117 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACEDBDI_04118 1e-139 focA P Formate/nitrite transporter
HACEDBDI_04119 2e-149 sacT K transcriptional antiterminator
HACEDBDI_04121 0.0 vpr O Belongs to the peptidase S8 family
HACEDBDI_04122 8.1e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HACEDBDI_04123 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HACEDBDI_04124 2.9e-202 rodA D Belongs to the SEDS family
HACEDBDI_04125 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HACEDBDI_04126 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HACEDBDI_04127 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HACEDBDI_04128 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HACEDBDI_04129 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HACEDBDI_04130 1e-35 ywzA S membrane
HACEDBDI_04131 1.8e-300 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HACEDBDI_04132 1.4e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HACEDBDI_04133 9.5e-60 gtcA S GtrA-like protein
HACEDBDI_04134 1.1e-121 ywcC K transcriptional regulator
HACEDBDI_04136 9.8e-49 ywcB S Protein of unknown function, DUF485
HACEDBDI_04137 2e-267 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HACEDBDI_04138 1e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HACEDBDI_04139 1.4e-223 ywbN P Dyp-type peroxidase family protein
HACEDBDI_04140 1.6e-184 ycdO P periplasmic lipoprotein involved in iron transport
HACEDBDI_04141 1.7e-252 P COG0672 High-affinity Fe2 Pb2 permease
HACEDBDI_04142 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HACEDBDI_04143 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HACEDBDI_04144 4.3e-153 ywbI K Transcriptional regulator
HACEDBDI_04145 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HACEDBDI_04146 2.3e-111 ywbG M effector of murein hydrolase
HACEDBDI_04147 3.6e-208 ywbF EGP Major facilitator Superfamily
HACEDBDI_04148 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HACEDBDI_04149 1.3e-221 ywbD 2.1.1.191 J Methyltransferase
HACEDBDI_04150 4.4e-67 ywbC 4.4.1.5 E glyoxalase
HACEDBDI_04151 2e-123 ywbB S Protein of unknown function (DUF2711)
HACEDBDI_04152 1.6e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HACEDBDI_04153 4.3e-275 epr 3.4.21.62 O Belongs to the peptidase S8 family
HACEDBDI_04154 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACEDBDI_04155 1.2e-152 sacY K transcriptional antiterminator
HACEDBDI_04156 7e-169 gspA M General stress
HACEDBDI_04157 3.3e-124 ywaF S Integral membrane protein
HACEDBDI_04158 4e-87 ywaE K Transcriptional regulator
HACEDBDI_04159 1.3e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HACEDBDI_04160 4.4e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HACEDBDI_04161 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HACEDBDI_04162 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HACEDBDI_04163 5e-14 S D-Ala-teichoic acid biosynthesis protein
HACEDBDI_04164 1.9e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACEDBDI_04165 8e-232 dltB M membrane protein involved in D-alanine export
HACEDBDI_04166 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACEDBDI_04167 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HACEDBDI_04168 4.3e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HACEDBDI_04169 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HACEDBDI_04170 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HACEDBDI_04171 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HACEDBDI_04172 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HACEDBDI_04173 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HACEDBDI_04174 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HACEDBDI_04175 1.1e-19 yxzF
HACEDBDI_04176 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HACEDBDI_04177 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HACEDBDI_04178 1.4e-212 yxlH EGP Major facilitator Superfamily
HACEDBDI_04179 2e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HACEDBDI_04180 1.5e-166 yxlF V ABC transporter, ATP-binding protein
HACEDBDI_04181 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
HACEDBDI_04182 1.7e-28
HACEDBDI_04183 8.1e-46 yxlC S Family of unknown function (DUF5345)
HACEDBDI_04184 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HACEDBDI_04185 3.3e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HACEDBDI_04186 7.7e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HACEDBDI_04187 0.0 cydD V ATP-binding protein
HACEDBDI_04188 3.4e-308 cydD V ATP-binding
HACEDBDI_04189 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HACEDBDI_04190 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
HACEDBDI_04191 2.1e-228 cimH C COG3493 Na citrate symporter
HACEDBDI_04192 6.7e-309 3.4.24.84 O Peptidase family M48
HACEDBDI_04194 7.3e-155 yxkH G Polysaccharide deacetylase
HACEDBDI_04195 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HACEDBDI_04196 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
HACEDBDI_04197 9.7e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HACEDBDI_04198 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HACEDBDI_04199 2.8e-74 yxkC S Domain of unknown function (DUF4352)
HACEDBDI_04200 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HACEDBDI_04201 7.7e-77 S Protein of unknown function (DUF1453)
HACEDBDI_04202 1.6e-190 yxjM T Signal transduction histidine kinase
HACEDBDI_04203 9.8e-115 K helix_turn_helix, Lux Regulon
HACEDBDI_04204 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HACEDBDI_04206 1.6e-85 yxjI S LURP-one-related
HACEDBDI_04207 5.5e-61 yxjG 2.1.1.14 E Methionine synthase
HACEDBDI_04208 2.2e-133 yxjG 2.1.1.14 E Methionine synthase
HACEDBDI_04209 3.7e-218 yxjG 2.1.1.14 E Methionine synthase
HACEDBDI_04210 6.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HACEDBDI_04211 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HACEDBDI_04212 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HACEDBDI_04213 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
HACEDBDI_04214 2.3e-156 rlmA 2.1.1.187 Q Methyltransferase domain
HACEDBDI_04215 1.2e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HACEDBDI_04216 1.3e-101 T Domain of unknown function (DUF4163)
HACEDBDI_04217 3e-47 yxiS
HACEDBDI_04218 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HACEDBDI_04219 6.6e-224 citH C Citrate transporter
HACEDBDI_04220 1.1e-143 exoK GH16 M licheninase activity
HACEDBDI_04221 8.3e-151 licT K transcriptional antiterminator
HACEDBDI_04222 6.8e-111
HACEDBDI_04223 6.8e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
HACEDBDI_04224 7.6e-247 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HACEDBDI_04225 4.3e-214 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HACEDBDI_04226 7.8e-55 padR K Transcriptional regulator PadR-like family
HACEDBDI_04227 6.5e-61 S Protein of unknown function (DUF2812)
HACEDBDI_04230 4.5e-43 yxiJ S YxiJ-like protein
HACEDBDI_04233 1.2e-34
HACEDBDI_04234 1.1e-83 yxiI S Protein of unknown function (DUF2716)
HACEDBDI_04235 1.5e-136
HACEDBDI_04236 8.3e-13 yxiG
HACEDBDI_04237 5.3e-16 yxiG
HACEDBDI_04238 1.9e-38 S Protein of unknown function (DUF2750)
HACEDBDI_04239 3.4e-52 yxxG
HACEDBDI_04240 1.2e-65 yxiG
HACEDBDI_04241 7.1e-44
HACEDBDI_04242 3.8e-76
HACEDBDI_04243 4.7e-94 S Protein of unknown function (DUF4240)
HACEDBDI_04244 4.5e-141
HACEDBDI_04246 7e-55
HACEDBDI_04247 6.1e-80 wapA M COG3209 Rhs family protein
HACEDBDI_04248 4.1e-14 yxiJ S YxiJ-like protein
HACEDBDI_04249 0.0 wapA M COG3209 Rhs family protein
HACEDBDI_04250 6.2e-163 yxxF EG EamA-like transporter family
HACEDBDI_04251 1.1e-72 yxiE T Belongs to the universal stress protein A family
HACEDBDI_04252 3.5e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HACEDBDI_04253 2.3e-310 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACEDBDI_04254 1.9e-44
HACEDBDI_04255 1.8e-60
HACEDBDI_04256 3.2e-68
HACEDBDI_04257 2.7e-70
HACEDBDI_04258 2.9e-68 S 37-kD nucleoid-associated bacterial protein
HACEDBDI_04259 5.2e-56
HACEDBDI_04260 5.7e-217 S nuclease activity
HACEDBDI_04261 4e-38 yxiC S Family of unknown function (DUF5344)
HACEDBDI_04262 2.3e-20 S Domain of unknown function (DUF5082)
HACEDBDI_04263 2.8e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HACEDBDI_04264 1.1e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HACEDBDI_04265 4.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
HACEDBDI_04266 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HACEDBDI_04267 3.5e-233 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HACEDBDI_04268 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HACEDBDI_04269 3.4e-250 lysP E amino acid
HACEDBDI_04270 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HACEDBDI_04271 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HACEDBDI_04272 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HACEDBDI_04273 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HACEDBDI_04274 2e-152 yxxB S Domain of Unknown Function (DUF1206)
HACEDBDI_04275 3.5e-197 eutH E Ethanolamine utilisation protein, EutH
HACEDBDI_04276 1.5e-247 yxeQ S MmgE/PrpD family
HACEDBDI_04277 4.7e-213 yxeP 3.5.1.47 E hydrolase activity
HACEDBDI_04278 3.5e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HACEDBDI_04279 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
HACEDBDI_04280 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HACEDBDI_04281 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HACEDBDI_04282 5.4e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HACEDBDI_04283 2.2e-182 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HACEDBDI_04284 9.2e-147 yidA S hydrolases of the HAD superfamily
HACEDBDI_04287 1.3e-20 yxeE
HACEDBDI_04289 8.6e-67
HACEDBDI_04290 1.5e-175 fhuD P ABC transporter
HACEDBDI_04291 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HACEDBDI_04292 0.0 yxdM V ABC transporter (permease)
HACEDBDI_04293 9.4e-141 yxdL V ABC transporter, ATP-binding protein
HACEDBDI_04294 2e-180 T PhoQ Sensor
HACEDBDI_04295 9.3e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACEDBDI_04296 3.3e-158 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HACEDBDI_04297 1.6e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HACEDBDI_04298 2.5e-166 iolH G Xylose isomerase-like TIM barrel
HACEDBDI_04299 3.1e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HACEDBDI_04300 4.7e-233 iolF EGP Major facilitator Superfamily
HACEDBDI_04301 1e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HACEDBDI_04302 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HACEDBDI_04303 3.2e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HACEDBDI_04304 6.6e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HACEDBDI_04305 3.9e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HACEDBDI_04306 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HACEDBDI_04307 3.7e-176 iolS C Aldo keto reductase
HACEDBDI_04309 8.3e-48 yxcD S Protein of unknown function (DUF2653)
HACEDBDI_04310 3.6e-244 csbC EGP Major facilitator Superfamily
HACEDBDI_04311 0.0 htpG O Molecular chaperone. Has ATPase activity
HACEDBDI_04313 4.8e-151 IQ Enoyl-(Acyl carrier protein) reductase
HACEDBDI_04314 3.7e-210 yxbF K Bacterial regulatory proteins, tetR family
HACEDBDI_04315 1.9e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HACEDBDI_04316 2.2e-31 yxaI S membrane protein domain
HACEDBDI_04317 1.8e-61 S Family of unknown function (DUF5391)
HACEDBDI_04318 1.4e-75 yxaI S membrane protein domain
HACEDBDI_04319 3.1e-223 P Protein of unknown function (DUF418)
HACEDBDI_04320 1.9e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
HACEDBDI_04321 1.3e-99 yxaF K Transcriptional regulator
HACEDBDI_04322 4.4e-197 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HACEDBDI_04323 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HACEDBDI_04324 6.2e-48 S LrgA family
HACEDBDI_04325 5e-117 yxaC M effector of murein hydrolase
HACEDBDI_04326 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
HACEDBDI_04327 8e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HACEDBDI_04328 2.8e-126 gntR K transcriptional
HACEDBDI_04329 8.6e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HACEDBDI_04330 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
HACEDBDI_04331 8.5e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HACEDBDI_04332 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HACEDBDI_04333 1.9e-286 ahpF O Alkyl hydroperoxide reductase
HACEDBDI_04334 7.8e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HACEDBDI_04335 5.3e-31 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HACEDBDI_04336 3.8e-128 yydK K Transcriptional regulator
HACEDBDI_04337 9.5e-119 S ABC-2 family transporter protein
HACEDBDI_04338 1.6e-109 prrC P ABC transporter
HACEDBDI_04339 4.2e-133 yydH O Peptidase M50
HACEDBDI_04340 1e-184 S Radical SAM superfamily
HACEDBDI_04341 2.3e-11
HACEDBDI_04342 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HACEDBDI_04343 5.4e-18
HACEDBDI_04344 3.2e-105 mjecl24 D Involved in chromosome partitioning
HACEDBDI_04345 1.4e-11
HACEDBDI_04346 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HACEDBDI_04347 1.1e-09 S YyzF-like protein
HACEDBDI_04348 4.2e-63
HACEDBDI_04349 4.3e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HACEDBDI_04351 5.7e-31 yycQ S Protein of unknown function (DUF2651)
HACEDBDI_04352 4.3e-206 yycP
HACEDBDI_04353 2.7e-129 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HACEDBDI_04354 1.6e-82 yycN 2.3.1.128 K Acetyltransferase
HACEDBDI_04355 9.4e-187 S aspartate phosphatase
HACEDBDI_04357 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HACEDBDI_04358 9.7e-261 rocE E amino acid
HACEDBDI_04359 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HACEDBDI_04360 7.4e-16
HACEDBDI_04361 2.8e-94
HACEDBDI_04362 2.3e-24 S Sporulation delaying protein SdpA
HACEDBDI_04363 1.5e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HACEDBDI_04364 1.5e-40 sdpR K transcriptional
HACEDBDI_04365 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HACEDBDI_04366 2.7e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HACEDBDI_04367 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HACEDBDI_04368 1.2e-154 yycI S protein conserved in bacteria
HACEDBDI_04369 2e-258 yycH S protein conserved in bacteria
HACEDBDI_04370 0.0 vicK 2.7.13.3 T Histidine kinase
HACEDBDI_04371 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACEDBDI_04376 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HACEDBDI_04377 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HACEDBDI_04378 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HACEDBDI_04379 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HACEDBDI_04381 1.9e-15 yycC K YycC-like protein
HACEDBDI_04382 8.4e-221 yeaN P COG2807 Cyanate permease
HACEDBDI_04383 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HACEDBDI_04384 2.2e-73 rplI J binds to the 23S rRNA
HACEDBDI_04385 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HACEDBDI_04386 8.3e-160 yybS S membrane
HACEDBDI_04388 3.9e-84 cotF M Spore coat protein
HACEDBDI_04389 3.4e-67 ydeP3 K Transcriptional regulator
HACEDBDI_04390 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HACEDBDI_04391 1.3e-70
HACEDBDI_04393 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HACEDBDI_04394 4.3e-111 K TipAS antibiotic-recognition domain
HACEDBDI_04395 2.1e-124
HACEDBDI_04396 1.5e-65 yybH S SnoaL-like domain
HACEDBDI_04397 2.1e-122 yybG S Pentapeptide repeat-containing protein
HACEDBDI_04398 1.1e-217 ynfM EGP Major facilitator Superfamily
HACEDBDI_04399 6.9e-164 yybE K Transcriptional regulator
HACEDBDI_04400 1.4e-77 yjcF S Acetyltransferase (GNAT) domain
HACEDBDI_04401 1.2e-74 yybC
HACEDBDI_04402 1.4e-124 S Metallo-beta-lactamase superfamily
HACEDBDI_04403 5.6e-77 yybA 2.3.1.57 K transcriptional
HACEDBDI_04404 4.5e-71 yjcF S Acetyltransferase (GNAT) domain
HACEDBDI_04405 5e-97 yyaS S Membrane
HACEDBDI_04406 1.3e-93 yyaR K Acetyltransferase (GNAT) domain
HACEDBDI_04407 3.5e-66 yyaQ S YjbR
HACEDBDI_04408 3.8e-107 yyaP 1.5.1.3 H RibD C-terminal domain
HACEDBDI_04409 9.5e-245 tetL EGP Major facilitator Superfamily
HACEDBDI_04410 1.7e-26 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HACEDBDI_04411 2.1e-23 yyaR K acetyltransferase
HACEDBDI_04413 3.8e-53 L Recombinase
HACEDBDI_04415 7.8e-61
HACEDBDI_04417 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HACEDBDI_04418 6.4e-165 yyaK S CAAX protease self-immunity
HACEDBDI_04419 4.7e-244 EGP Major facilitator superfamily
HACEDBDI_04420 7.6e-92 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HACEDBDI_04421 2.6e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HACEDBDI_04422 6.8e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HACEDBDI_04423 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
HACEDBDI_04424 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HACEDBDI_04425 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HACEDBDI_04426 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HACEDBDI_04427 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HACEDBDI_04428 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HACEDBDI_04429 2.3e-33 yyzM S protein conserved in bacteria
HACEDBDI_04430 8.1e-177 yyaD S Membrane
HACEDBDI_04431 2.8e-111 yyaC S Sporulation protein YyaC
HACEDBDI_04432 6e-149 spo0J K Belongs to the ParB family
HACEDBDI_04433 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HACEDBDI_04434 5.7e-74 S Bacterial PH domain
HACEDBDI_04435 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HACEDBDI_04436 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HACEDBDI_04437 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HACEDBDI_04438 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HACEDBDI_04439 6.5e-108 jag S single-stranded nucleic acid binding R3H
HACEDBDI_04440 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)