ORF_ID e_value Gene_name EC_number CAZy COGs Description
COJEOIIM_00001 1.6e-197 dtpT U amino acid peptide transporter
COJEOIIM_00002 1.1e-07
COJEOIIM_00004 5.9e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COJEOIIM_00005 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
COJEOIIM_00006 2.5e-90 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
COJEOIIM_00007 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COJEOIIM_00008 3.6e-130 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COJEOIIM_00009 8.2e-251 yhgF K Tex-like protein N-terminal domain protein
COJEOIIM_00010 7.2e-45 ydcK S Belongs to the SprT family
COJEOIIM_00012 1.3e-115 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COJEOIIM_00013 5.9e-129 mleP2 S Sodium Bile acid symporter family
COJEOIIM_00014 4.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COJEOIIM_00015 1e-33 S Enterocin A Immunity
COJEOIIM_00016 7.6e-223 pepC 3.4.22.40 E Peptidase C1-like family
COJEOIIM_00017 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
COJEOIIM_00018 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
COJEOIIM_00019 5.4e-224 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COJEOIIM_00020 4.1e-153 yacL S domain protein
COJEOIIM_00021 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COJEOIIM_00022 1.8e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
COJEOIIM_00023 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COJEOIIM_00024 3.2e-109 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COJEOIIM_00025 5.4e-71 yacP S YacP-like NYN domain
COJEOIIM_00026 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COJEOIIM_00027 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COJEOIIM_00028 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
COJEOIIM_00029 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COJEOIIM_00030 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COJEOIIM_00031 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COJEOIIM_00032 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COJEOIIM_00033 1.4e-54
COJEOIIM_00034 1.6e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COJEOIIM_00035 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COJEOIIM_00036 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COJEOIIM_00037 4.8e-45 nrdI F NrdI Flavodoxin like
COJEOIIM_00038 1.2e-27 nrdH O Glutaredoxin
COJEOIIM_00039 1.1e-75 rsmC 2.1.1.172 J Methyltransferase
COJEOIIM_00040 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COJEOIIM_00041 4.3e-210 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COJEOIIM_00042 1.4e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COJEOIIM_00043 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COJEOIIM_00044 9.2e-29 yaaL S Protein of unknown function (DUF2508)
COJEOIIM_00045 1.4e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COJEOIIM_00046 3.9e-83 holB 2.7.7.7 L DNA polymerase III
COJEOIIM_00047 1.4e-40 yabA L Involved in initiation control of chromosome replication
COJEOIIM_00048 4.1e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COJEOIIM_00049 4.7e-81 fat 3.1.2.21 I Acyl-ACP thioesterase
COJEOIIM_00050 3.5e-140 ansA 3.5.1.1 EJ Asparaginase
COJEOIIM_00051 3.7e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
COJEOIIM_00052 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
COJEOIIM_00053 8.4e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COJEOIIM_00054 6.9e-257 uup S ABC transporter, ATP-binding protein
COJEOIIM_00055 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COJEOIIM_00056 2.4e-33 S CAAX protease self-immunity
COJEOIIM_00057 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COJEOIIM_00058 1.3e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COJEOIIM_00059 2.5e-269 aha1 P COG COG0474 Cation transport ATPase
COJEOIIM_00060 1.2e-295 ydaO E amino acid
COJEOIIM_00061 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
COJEOIIM_00062 3.2e-128 comFA L Helicase C-terminal domain protein
COJEOIIM_00063 5.6e-44 comFC S Competence protein
COJEOIIM_00064 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COJEOIIM_00065 9.1e-95 yeaN P Major Facilitator Superfamily
COJEOIIM_00066 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COJEOIIM_00067 2.2e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COJEOIIM_00068 9.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
COJEOIIM_00069 1.7e-85 K response regulator
COJEOIIM_00070 1.2e-85 phoR 2.7.13.3 T Histidine kinase
COJEOIIM_00071 2.4e-08 pspC KT PspC domain
COJEOIIM_00072 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
COJEOIIM_00073 8.7e-133 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COJEOIIM_00074 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COJEOIIM_00075 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
COJEOIIM_00076 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COJEOIIM_00077 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COJEOIIM_00078 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COJEOIIM_00079 5e-79 ylbE GM NAD dependent epimerase dehydratase family protein
COJEOIIM_00080 7.5e-126 rapZ S Displays ATPase and GTPase activities
COJEOIIM_00081 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
COJEOIIM_00082 1.8e-149 whiA K May be required for sporulation
COJEOIIM_00083 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COJEOIIM_00085 1.4e-136 cggR K Putative sugar-binding domain
COJEOIIM_00086 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COJEOIIM_00087 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
COJEOIIM_00088 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COJEOIIM_00089 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COJEOIIM_00090 2.2e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COJEOIIM_00091 5e-104 K response regulator
COJEOIIM_00092 1.8e-169 T PhoQ Sensor
COJEOIIM_00093 6.7e-146 lmrP E Major Facilitator Superfamily
COJEOIIM_00094 6e-179 clcA P chloride
COJEOIIM_00095 2.8e-19 secG U Preprotein translocase
COJEOIIM_00096 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COJEOIIM_00097 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COJEOIIM_00098 9.1e-42 yxjI
COJEOIIM_00099 2.4e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
COJEOIIM_00100 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COJEOIIM_00101 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
COJEOIIM_00102 3.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
COJEOIIM_00103 1.9e-68 dnaQ 2.7.7.7 L DNA polymerase III
COJEOIIM_00104 3.5e-115 murB 1.3.1.98 M Cell wall formation
COJEOIIM_00105 2.4e-71 S Protein of unknown function (DUF1361)
COJEOIIM_00106 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COJEOIIM_00107 5.3e-68 ybbR S YbbR-like protein
COJEOIIM_00108 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COJEOIIM_00109 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
COJEOIIM_00110 4e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
COJEOIIM_00111 3.2e-21 cutC P Participates in the control of copper homeostasis
COJEOIIM_00112 4e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COJEOIIM_00113 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COJEOIIM_00114 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
COJEOIIM_00115 4.1e-97 rrmA 2.1.1.187 H Methyltransferase
COJEOIIM_00116 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COJEOIIM_00117 1.6e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
COJEOIIM_00118 3.5e-108 ymfF S Peptidase M16 inactive domain protein
COJEOIIM_00119 3e-147 ymfH S Peptidase M16
COJEOIIM_00120 8.4e-91 IQ Enoyl-(Acyl carrier protein) reductase
COJEOIIM_00121 2.9e-64 ymfM S Helix-turn-helix domain
COJEOIIM_00122 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COJEOIIM_00123 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COJEOIIM_00124 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
COJEOIIM_00125 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COJEOIIM_00126 6e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COJEOIIM_00127 1e-70 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COJEOIIM_00128 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COJEOIIM_00129 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
COJEOIIM_00130 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
COJEOIIM_00131 1.8e-12 yajC U Preprotein translocase
COJEOIIM_00133 3.3e-61 uspA T universal stress protein
COJEOIIM_00135 2e-208 yfnA E Amino Acid
COJEOIIM_00136 6.9e-117 lutA C Cysteine-rich domain
COJEOIIM_00137 2.1e-245 lutB C 4Fe-4S dicluster domain
COJEOIIM_00138 1.9e-66 yrjD S LUD domain
COJEOIIM_00139 1e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COJEOIIM_00140 7.5e-13
COJEOIIM_00141 2.7e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
COJEOIIM_00142 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
COJEOIIM_00143 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COJEOIIM_00144 2.1e-36 yrzL S Belongs to the UPF0297 family
COJEOIIM_00145 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COJEOIIM_00146 1.9e-33 yrzB S Belongs to the UPF0473 family
COJEOIIM_00147 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
COJEOIIM_00148 9.5e-18 cvpA S Colicin V production protein
COJEOIIM_00149 3.9e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COJEOIIM_00150 9.9e-41 trxA O Belongs to the thioredoxin family
COJEOIIM_00151 9e-34 yslB S Protein of unknown function (DUF2507)
COJEOIIM_00152 2.2e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COJEOIIM_00153 6.7e-42 S Phosphoesterase
COJEOIIM_00156 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COJEOIIM_00157 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COJEOIIM_00158 1.1e-213 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COJEOIIM_00159 4.8e-199 oatA I Acyltransferase
COJEOIIM_00160 1.4e-16
COJEOIIM_00162 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COJEOIIM_00163 6.5e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
COJEOIIM_00164 4e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
COJEOIIM_00165 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COJEOIIM_00166 4.6e-296 S membrane
COJEOIIM_00167 1.5e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
COJEOIIM_00168 1.8e-27 S Protein of unknown function (DUF3290)
COJEOIIM_00169 3.3e-75 yviA S Protein of unknown function (DUF421)
COJEOIIM_00171 4.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COJEOIIM_00172 7.7e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
COJEOIIM_00173 1.1e-53 tag 3.2.2.20 L glycosylase
COJEOIIM_00174 6e-72 usp6 T universal stress protein
COJEOIIM_00176 5.1e-184 rarA L recombination factor protein RarA
COJEOIIM_00177 3.4e-24 yueI S Protein of unknown function (DUF1694)
COJEOIIM_00178 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COJEOIIM_00179 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
COJEOIIM_00180 5.8e-175 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
COJEOIIM_00181 6.4e-162 iscS2 2.8.1.7 E Aminotransferase class V
COJEOIIM_00182 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COJEOIIM_00183 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COJEOIIM_00184 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
COJEOIIM_00185 8.1e-80 radC L DNA repair protein
COJEOIIM_00186 4.5e-21 K Cold shock
COJEOIIM_00187 3.6e-156 mreB D cell shape determining protein MreB
COJEOIIM_00188 2.1e-88 mreC M Involved in formation and maintenance of cell shape
COJEOIIM_00189 2e-54 mreD M rod shape-determining protein MreD
COJEOIIM_00190 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
COJEOIIM_00191 1.8e-126 minD D Belongs to the ParA family
COJEOIIM_00192 1.9e-94 glnP P ABC transporter permease
COJEOIIM_00193 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COJEOIIM_00194 3.7e-109 aatB ET ABC transporter substrate-binding protein
COJEOIIM_00195 9.8e-100 D Alpha beta
COJEOIIM_00197 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
COJEOIIM_00198 2.2e-07 S Protein of unknown function (DUF3397)
COJEOIIM_00199 1.5e-55 mraZ K Belongs to the MraZ family
COJEOIIM_00200 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COJEOIIM_00201 2.5e-11 ftsL D cell division protein FtsL
COJEOIIM_00202 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
COJEOIIM_00203 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COJEOIIM_00204 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COJEOIIM_00205 1.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COJEOIIM_00206 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
COJEOIIM_00207 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
COJEOIIM_00208 9.8e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COJEOIIM_00209 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COJEOIIM_00210 3e-19 yggT S YGGT family
COJEOIIM_00211 1.7e-81 ylmH S S4 domain protein
COJEOIIM_00212 8.6e-62 divIVA D DivIVA domain protein
COJEOIIM_00213 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COJEOIIM_00214 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COJEOIIM_00215 4.4e-74 draG O ADP-ribosylglycohydrolase
COJEOIIM_00217 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
COJEOIIM_00218 1.4e-92 T Calcineurin-like phosphoesterase superfamily domain
COJEOIIM_00219 5.5e-49 lytE M LysM domain protein
COJEOIIM_00220 5e-19 glpE P Rhodanese Homology Domain
COJEOIIM_00221 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
COJEOIIM_00222 6.9e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
COJEOIIM_00223 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
COJEOIIM_00224 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
COJEOIIM_00225 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
COJEOIIM_00226 3.6e-220 cydD CO ABC transporter transmembrane region
COJEOIIM_00227 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COJEOIIM_00228 1.5e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
COJEOIIM_00229 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
COJEOIIM_00230 1.5e-146 pbuO_1 S Permease family
COJEOIIM_00232 2.4e-32 2.7.7.65 T GGDEF domain
COJEOIIM_00233 1.7e-129 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
COJEOIIM_00234 6.5e-183
COJEOIIM_00235 5.8e-206 S Protein conserved in bacteria
COJEOIIM_00236 1.2e-201 ydaM M Glycosyl transferase family group 2
COJEOIIM_00237 0.0 ydaN S Bacterial cellulose synthase subunit
COJEOIIM_00238 2.4e-113 2.7.7.65 T diguanylate cyclase activity
COJEOIIM_00239 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
COJEOIIM_00240 1.9e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
COJEOIIM_00241 2.5e-37 L Helicase C-terminal domain protein
COJEOIIM_00242 1.6e-202 L Helicase C-terminal domain protein
COJEOIIM_00243 4.7e-24 L Helicase C-terminal domain protein
COJEOIIM_00244 0.0 rafA 3.2.1.22 G alpha-galactosidase
COJEOIIM_00245 8.9e-54 S Membrane
COJEOIIM_00246 3.5e-64 K helix_turn_helix, arabinose operon control protein
COJEOIIM_00247 2.3e-45
COJEOIIM_00248 1.3e-204 pipD E Dipeptidase
COJEOIIM_00249 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
COJEOIIM_00250 2e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COJEOIIM_00251 4.5e-60 speG J Acetyltransferase (GNAT) domain
COJEOIIM_00252 2.3e-113 yitU 3.1.3.104 S hydrolase
COJEOIIM_00253 1.6e-79 yjfP S COG1073 Hydrolases of the alpha beta superfamily
COJEOIIM_00254 4.8e-81
COJEOIIM_00255 2e-178 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
COJEOIIM_00256 6.7e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
COJEOIIM_00257 1.4e-48 cps4C M Chain length determinant protein
COJEOIIM_00258 9.4e-65 cpsD D AAA domain
COJEOIIM_00259 1.2e-221 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
COJEOIIM_00260 9.1e-167 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
COJEOIIM_00261 4.8e-77 epsL M Bacterial sugar transferase
COJEOIIM_00262 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
COJEOIIM_00263 5.3e-121 2.4.1.52 GT4 M Glycosyl transferases group 1
COJEOIIM_00264 1.8e-79 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
COJEOIIM_00265 1.5e-75 M Glycosyltransferase Family 4
COJEOIIM_00266 1e-42 GT2 V Glycosyl transferase, family 2
COJEOIIM_00267 2.5e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
COJEOIIM_00269 2.7e-52
COJEOIIM_00270 2.3e-116 S Glycosyltransferase WbsX
COJEOIIM_00271 3.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
COJEOIIM_00272 2.2e-104 cps2I S Psort location CytoplasmicMembrane, score
COJEOIIM_00273 5.5e-147 lspL 5.1.3.6 GM RmlD substrate binding domain
COJEOIIM_00274 4.1e-178 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
COJEOIIM_00275 1.3e-108 M Glycosyl transferases group 1
COJEOIIM_00278 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
COJEOIIM_00279 2.1e-39 K Transcriptional regulator
COJEOIIM_00280 4.5e-30 S CHY zinc finger
COJEOIIM_00281 5e-86 1.1.1.1 C Zinc-binding dehydrogenase
COJEOIIM_00283 4.4e-41 S Protein of unknown function (DUF1211)
COJEOIIM_00284 1.4e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
COJEOIIM_00286 2.5e-41 wecD M Acetyltransferase (GNAT) family
COJEOIIM_00287 3.8e-75 cps2D 5.1.3.2 M RmlD substrate binding domain
COJEOIIM_00288 1.2e-65 H Methyltransferase domain
COJEOIIM_00290 1.3e-16 K DNA-templated transcription, initiation
COJEOIIM_00292 2.2e-08 S Protein of unknown function (DUF2922)
COJEOIIM_00295 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
COJEOIIM_00296 1e-27 ysxB J Cysteine protease Prp
COJEOIIM_00297 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
COJEOIIM_00298 4.7e-09 M LysM domain
COJEOIIM_00301 4.3e-29
COJEOIIM_00302 2.5e-16
COJEOIIM_00303 1.2e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
COJEOIIM_00304 1.3e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
COJEOIIM_00305 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
COJEOIIM_00306 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
COJEOIIM_00307 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
COJEOIIM_00308 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COJEOIIM_00309 4.5e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COJEOIIM_00310 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COJEOIIM_00311 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COJEOIIM_00312 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COJEOIIM_00313 4.1e-51 yeaL S Protein of unknown function (DUF441)
COJEOIIM_00314 4.8e-125 cvfB S S1 domain
COJEOIIM_00315 7.3e-113 xerD D recombinase XerD
COJEOIIM_00316 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
COJEOIIM_00317 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COJEOIIM_00318 4.4e-189 nhaC C Na H antiporter NhaC
COJEOIIM_00319 1e-64 ypsA S Belongs to the UPF0398 family
COJEOIIM_00320 1.2e-196 ade 3.5.4.2 F Adenine deaminase C-terminal domain
COJEOIIM_00322 4.4e-74 2.3.1.178 M GNAT acetyltransferase
COJEOIIM_00323 2.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
COJEOIIM_00324 2.8e-56 3.6.1.27 I Acid phosphatase homologues
COJEOIIM_00325 4.9e-22 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
COJEOIIM_00327 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
COJEOIIM_00328 5.2e-202 hsdM 2.1.1.72 V type I restriction-modification system
COJEOIIM_00329 6.9e-54 K Transcriptional regulator C-terminal region
COJEOIIM_00330 7.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
COJEOIIM_00331 1.3e-284 pepO 3.4.24.71 O Peptidase family M13
COJEOIIM_00332 1.7e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
COJEOIIM_00333 5e-09 yvaZ S Protein of unknown function (DUF1648)
COJEOIIM_00334 2.1e-69 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
COJEOIIM_00335 3.9e-47 hmpT S ECF-type riboflavin transporter, S component
COJEOIIM_00336 5.1e-42 wecD K Acetyltransferase GNAT Family
COJEOIIM_00338 1.2e-253 XK27_06780 V ABC transporter permease
COJEOIIM_00339 6.4e-96 XK27_06785 V ABC transporter, ATP-binding protein
COJEOIIM_00341 7.5e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COJEOIIM_00342 6.9e-121 ytbE S reductase
COJEOIIM_00343 4.2e-43 ytcD K HxlR-like helix-turn-helix
COJEOIIM_00344 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
COJEOIIM_00345 2e-67 ybbL S ABC transporter
COJEOIIM_00346 8.1e-163 oxlT P Major Facilitator Superfamily
COJEOIIM_00347 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COJEOIIM_00348 3.1e-47 S Short repeat of unknown function (DUF308)
COJEOIIM_00349 1.8e-30 tetR K Transcriptional regulator C-terminal region
COJEOIIM_00350 1.2e-150 yfeX P Peroxidase
COJEOIIM_00351 2.5e-16 S Protein of unknown function (DUF3021)
COJEOIIM_00352 4.5e-39 K LytTr DNA-binding domain
COJEOIIM_00353 7.6e-113 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
COJEOIIM_00354 2.2e-209 mmuP E amino acid
COJEOIIM_00355 1.2e-15 psiE S Phosphate-starvation-inducible E
COJEOIIM_00356 3.7e-155 oppF P Belongs to the ABC transporter superfamily
COJEOIIM_00357 1.3e-180 oppD P Belongs to the ABC transporter superfamily
COJEOIIM_00358 5.8e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
COJEOIIM_00359 1e-141 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
COJEOIIM_00360 1.4e-202 oppA E ABC transporter, substratebinding protein
COJEOIIM_00361 9.1e-219 yifK E Amino acid permease
COJEOIIM_00362 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COJEOIIM_00363 8.2e-55 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
COJEOIIM_00364 5e-66 pgm3 G phosphoglycerate mutase family
COJEOIIM_00365 1.5e-251 ctpA 3.6.3.54 P P-type ATPase
COJEOIIM_00366 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
COJEOIIM_00367 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
COJEOIIM_00368 5.6e-150 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
COJEOIIM_00369 9.1e-22 K transcriptional regulator
COJEOIIM_00370 1.5e-76 hchA S intracellular protease amidase
COJEOIIM_00371 2.8e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
COJEOIIM_00372 3.1e-112 lacI3 K helix_turn _helix lactose operon repressor
COJEOIIM_00373 5.5e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
COJEOIIM_00374 2e-39 2.7.1.191 G PTS system fructose IIA component
COJEOIIM_00375 2.4e-123 G PTS system mannose/fructose/sorbose family IID component
COJEOIIM_00376 2.1e-106 G PTS system sorbose-specific iic component
COJEOIIM_00377 2e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
COJEOIIM_00378 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
COJEOIIM_00379 2.8e-139 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COJEOIIM_00380 2e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
COJEOIIM_00381 6.5e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
COJEOIIM_00382 1.2e-197 1.3.5.4 C FMN_bind
COJEOIIM_00383 2.2e-56 3.1.3.48 K Transcriptional regulator
COJEOIIM_00384 3.8e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
COJEOIIM_00385 4.5e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
COJEOIIM_00386 3.7e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
COJEOIIM_00387 9.3e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
COJEOIIM_00389 3.3e-96 S Domain of unknown function DUF87
COJEOIIM_00391 1.1e-229 V ABC transporter transmembrane region
COJEOIIM_00392 3.1e-216 XK27_09600 V ABC transporter, ATP-binding protein
COJEOIIM_00393 1.2e-31 K Transcriptional regulator, MarR family
COJEOIIM_00394 9.8e-173 S Putative peptidoglycan binding domain
COJEOIIM_00396 4e-23 relB L RelB antitoxin
COJEOIIM_00397 8.4e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
COJEOIIM_00398 1.1e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
COJEOIIM_00399 4.4e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
COJEOIIM_00400 1.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COJEOIIM_00401 3.5e-223 pepF E Oligopeptidase F
COJEOIIM_00402 2.2e-96 yicL EG EamA-like transporter family
COJEOIIM_00403 2.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
COJEOIIM_00404 4.4e-170 yjjP S Putative threonine/serine exporter
COJEOIIM_00405 2.8e-109 glcU U sugar transport
COJEOIIM_00406 3.8e-14 yobS K transcriptional regulator
COJEOIIM_00407 3.8e-152 mdtG EGP Major facilitator Superfamily
COJEOIIM_00408 3.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
COJEOIIM_00409 2.2e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
COJEOIIM_00410 1.5e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COJEOIIM_00411 3.6e-17 yneR
COJEOIIM_00412 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
COJEOIIM_00413 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COJEOIIM_00414 3.3e-12 yiiE S Protein of unknown function (DUF1211)
COJEOIIM_00415 3.7e-37 yiiE S Protein of unknown function (DUF1211)
COJEOIIM_00416 0.0 asnB 6.3.5.4 E Asparagine synthase
COJEOIIM_00417 7.4e-64 D peptidase
COJEOIIM_00418 9.5e-117 S Glycosyl transferase family 2
COJEOIIM_00419 2.5e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
COJEOIIM_00420 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COJEOIIM_00421 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COJEOIIM_00422 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
COJEOIIM_00423 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COJEOIIM_00424 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COJEOIIM_00425 9.3e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COJEOIIM_00426 9e-20 yaaA S S4 domain protein YaaA
COJEOIIM_00427 5.6e-158 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COJEOIIM_00428 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COJEOIIM_00429 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
COJEOIIM_00430 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COJEOIIM_00431 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COJEOIIM_00432 1.1e-199 nupG F Nucleoside
COJEOIIM_00433 2e-122 MA20_14895 S Conserved hypothetical protein 698
COJEOIIM_00434 2.9e-53 K LysR substrate binding domain
COJEOIIM_00435 9.6e-09
COJEOIIM_00436 2.3e-65 yxkH G Polysaccharide deacetylase
COJEOIIM_00437 2.6e-29 yqkB S Belongs to the HesB IscA family
COJEOIIM_00438 1.6e-55 jag S R3H domain protein
COJEOIIM_00439 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
COJEOIIM_00440 2e-31 azlD S Branched-chain amino acid transport protein (AzlD)
COJEOIIM_00441 2e-76 azlC E branched-chain amino acid
COJEOIIM_00442 5.5e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
COJEOIIM_00443 9.4e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
COJEOIIM_00444 4.7e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
COJEOIIM_00445 3.8e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
COJEOIIM_00446 1.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
COJEOIIM_00447 4.1e-75 XK27_02070 S Nitroreductase family
COJEOIIM_00448 1.7e-111 endA F DNA RNA non-specific endonuclease
COJEOIIM_00450 5.9e-210 brnQ U Component of the transport system for branched-chain amino acids
COJEOIIM_00451 6.5e-61 K Bacterial regulatory proteins, tetR family
COJEOIIM_00452 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
COJEOIIM_00453 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
COJEOIIM_00454 9.5e-69 dhaL 2.7.1.121 S Dak2
COJEOIIM_00455 4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
COJEOIIM_00456 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COJEOIIM_00457 9.8e-177 yjcE P Sodium proton antiporter
COJEOIIM_00458 4e-210 mtlR K Mga helix-turn-helix domain
COJEOIIM_00459 5.9e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COJEOIIM_00460 6.1e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
COJEOIIM_00461 3.2e-29 ponA V the current gene model (or a revised gene model) may contain a frame shift
COJEOIIM_00463 4.5e-102 tcyB E ABC transporter
COJEOIIM_00464 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COJEOIIM_00465 1.3e-95 tcyA ET Belongs to the bacterial solute-binding protein 3 family
COJEOIIM_00466 1.6e-38 K Transcriptional regulator
COJEOIIM_00467 2.2e-107 terC P Integral membrane protein TerC family
COJEOIIM_00468 4.2e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
COJEOIIM_00469 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COJEOIIM_00470 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
COJEOIIM_00471 1.1e-41 gntR1 K Transcriptional regulator, GntR family
COJEOIIM_00472 8e-96 V ABC transporter, ATP-binding protein
COJEOIIM_00473 2.5e-08
COJEOIIM_00474 1.1e-39 ybjQ S Belongs to the UPF0145 family
COJEOIIM_00475 4.7e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
COJEOIIM_00476 1.5e-96 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COJEOIIM_00477 1e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
COJEOIIM_00478 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COJEOIIM_00479 1.1e-33
COJEOIIM_00480 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
COJEOIIM_00481 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
COJEOIIM_00482 2.3e-63 srtA 3.4.22.70 M sortase family
COJEOIIM_00484 1.8e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
COJEOIIM_00485 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
COJEOIIM_00486 1.7e-147 scrR K helix_turn _helix lactose operon repressor
COJEOIIM_00487 1.8e-217 scrB 3.2.1.26 GH32 G invertase
COJEOIIM_00488 6.1e-282 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
COJEOIIM_00489 2e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
COJEOIIM_00490 2.1e-114 ntpJ P Potassium uptake protein
COJEOIIM_00491 2.2e-58 ktrA P TrkA-N domain
COJEOIIM_00492 5.7e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
COJEOIIM_00493 1.1e-43 K helix_turn_helix isocitrate lyase regulation
COJEOIIM_00494 5.3e-120 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COJEOIIM_00495 1.4e-102 pfoS S Phosphotransferase system, EIIC
COJEOIIM_00496 1.4e-19
COJEOIIM_00497 2e-93 S Predicted membrane protein (DUF2207)
COJEOIIM_00498 1.2e-54 bioY S BioY family
COJEOIIM_00499 5.7e-184 lmrB EGP Major facilitator Superfamily
COJEOIIM_00500 2.5e-95 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COJEOIIM_00501 7.6e-74 glcR K DeoR C terminal sensor domain
COJEOIIM_00502 1e-60 yceE S haloacid dehalogenase-like hydrolase
COJEOIIM_00503 1.9e-41 S CAAX protease self-immunity
COJEOIIM_00504 1.2e-33 S Domain of unknown function (DUF4811)
COJEOIIM_00505 2.1e-197 lmrB EGP Major facilitator Superfamily
COJEOIIM_00506 4.2e-32 merR K MerR HTH family regulatory protein
COJEOIIM_00507 1.8e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COJEOIIM_00508 9.1e-71 S Protein of unknown function (DUF554)
COJEOIIM_00509 6.9e-120 G Bacterial extracellular solute-binding protein
COJEOIIM_00510 3e-79 baeR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COJEOIIM_00511 7.9e-100 baeS T Histidine kinase
COJEOIIM_00512 7e-80 rbsB G sugar-binding domain protein
COJEOIIM_00513 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
COJEOIIM_00514 6.4e-116 manY G PTS system sorbose-specific iic component
COJEOIIM_00515 2.1e-147 manN G system, mannose fructose sorbose family IID component
COJEOIIM_00516 3.2e-52 manO S Domain of unknown function (DUF956)
COJEOIIM_00517 2.1e-70 mltD CBM50 M NlpC P60 family protein
COJEOIIM_00518 4.7e-130 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
COJEOIIM_00519 1.6e-163 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COJEOIIM_00520 2.4e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
COJEOIIM_00521 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
COJEOIIM_00522 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
COJEOIIM_00523 3e-106 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COJEOIIM_00524 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COJEOIIM_00525 2e-46 S CRISPR-associated protein (Cas_Csn2)
COJEOIIM_00526 6.3e-212 yfnA E Amino Acid
COJEOIIM_00527 5.4e-53 zur P Belongs to the Fur family
COJEOIIM_00528 3e-12 3.2.1.14 GH18
COJEOIIM_00529 5e-98
COJEOIIM_00530 1.3e-09
COJEOIIM_00531 3.7e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COJEOIIM_00532 1.9e-99 glnH ET ABC transporter
COJEOIIM_00533 1.2e-85 gluC P ABC transporter permease
COJEOIIM_00534 9.6e-78 glnP P ABC transporter permease
COJEOIIM_00535 9e-184 steT E amino acid
COJEOIIM_00536 6.5e-21 K Acetyltransferase (GNAT) domain
COJEOIIM_00537 2.1e-145 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
COJEOIIM_00538 2.6e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
COJEOIIM_00539 2.5e-78 K rpiR family
COJEOIIM_00540 4.3e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COJEOIIM_00541 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
COJEOIIM_00542 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COJEOIIM_00543 1e-100 rplD J Forms part of the polypeptide exit tunnel
COJEOIIM_00544 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COJEOIIM_00545 4.1e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COJEOIIM_00546 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COJEOIIM_00547 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COJEOIIM_00548 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COJEOIIM_00549 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COJEOIIM_00550 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
COJEOIIM_00551 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COJEOIIM_00552 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COJEOIIM_00553 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COJEOIIM_00554 2.4e-90 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COJEOIIM_00555 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COJEOIIM_00556 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COJEOIIM_00557 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COJEOIIM_00558 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COJEOIIM_00559 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COJEOIIM_00560 2.1e-22 rpmD J Ribosomal protein L30
COJEOIIM_00561 1e-67 rplO J Binds to the 23S rRNA
COJEOIIM_00562 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COJEOIIM_00563 3.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COJEOIIM_00564 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COJEOIIM_00565 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
COJEOIIM_00566 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COJEOIIM_00567 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COJEOIIM_00568 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COJEOIIM_00569 4.8e-53 rplQ J Ribosomal protein L17
COJEOIIM_00570 1.8e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COJEOIIM_00571 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COJEOIIM_00572 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COJEOIIM_00573 2.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COJEOIIM_00574 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COJEOIIM_00575 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
COJEOIIM_00576 5.7e-28
COJEOIIM_00577 3.1e-246 yjbQ P TrkA C-terminal domain protein
COJEOIIM_00578 0.0 helD 3.6.4.12 L DNA helicase
COJEOIIM_00579 4e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
COJEOIIM_00580 2.6e-109 hrtB V ABC transporter permease
COJEOIIM_00581 1.9e-33 ygfC K transcriptional regulator (TetR family)
COJEOIIM_00582 1.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
COJEOIIM_00583 1.1e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
COJEOIIM_00584 6.8e-35 M LysM domain protein
COJEOIIM_00585 9.8e-115 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
COJEOIIM_00586 2.3e-155 amtB P ammonium transporter
COJEOIIM_00587 2.8e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
COJEOIIM_00588 6.6e-46 argR K Regulates arginine biosynthesis genes
COJEOIIM_00589 4.2e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
COJEOIIM_00590 1.7e-90 S Alpha/beta hydrolase of unknown function (DUF915)
COJEOIIM_00591 1.2e-22 veg S Biofilm formation stimulator VEG
COJEOIIM_00592 7.5e-134 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COJEOIIM_00593 1.7e-86 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
COJEOIIM_00594 8.3e-105 tatD L hydrolase, TatD family
COJEOIIM_00595 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COJEOIIM_00596 4.3e-127
COJEOIIM_00597 2.1e-153 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
COJEOIIM_00598 7.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
COJEOIIM_00599 2.3e-31 K Transcriptional regulator
COJEOIIM_00600 3.5e-104 ybhR V ABC transporter
COJEOIIM_00601 8.4e-83 ybhF_2 V abc transporter atp-binding protein
COJEOIIM_00602 9.4e-103 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
COJEOIIM_00603 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
COJEOIIM_00604 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COJEOIIM_00605 2.3e-272 helD 3.6.4.12 L DNA helicase
COJEOIIM_00607 1.3e-114 htpX O Belongs to the peptidase M48B family
COJEOIIM_00608 1.5e-71 lemA S LemA family
COJEOIIM_00609 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
COJEOIIM_00610 3.2e-45 yjcF K protein acetylation
COJEOIIM_00612 3.3e-253 yfiC V ABC transporter
COJEOIIM_00613 3.6e-172 lmrA V ABC transporter, ATP-binding protein
COJEOIIM_00614 4.6e-37 lmrA V ABC transporter, ATP-binding protein
COJEOIIM_00615 5.8e-35 K Bacterial regulatory proteins, tetR family
COJEOIIM_00616 7.3e-246 yhcA V ABC transporter, ATP-binding protein
COJEOIIM_00617 7e-224 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COJEOIIM_00618 4.3e-116 G Transporter, major facilitator family protein
COJEOIIM_00619 1.9e-20 G Transporter, major facilitator family protein
COJEOIIM_00620 2.2e-90 lacX 5.1.3.3 G Aldose 1-epimerase
COJEOIIM_00621 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
COJEOIIM_00622 2.5e-113 K response regulator
COJEOIIM_00623 1.2e-89 patB 4.4.1.8 E Aminotransferase, class I
COJEOIIM_00624 1.3e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
COJEOIIM_00625 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COJEOIIM_00626 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COJEOIIM_00627 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COJEOIIM_00628 9.3e-21 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
COJEOIIM_00629 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COJEOIIM_00630 0.0 L Helicase C-terminal domain protein
COJEOIIM_00631 2.7e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
COJEOIIM_00632 2.1e-180 yhdP S Transporter associated domain
COJEOIIM_00633 4.8e-26
COJEOIIM_00634 3.7e-75 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COJEOIIM_00635 9.6e-132 bacI V MacB-like periplasmic core domain
COJEOIIM_00636 9.6e-97 V ABC transporter
COJEOIIM_00637 2.2e-63 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COJEOIIM_00638 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
COJEOIIM_00639 3.6e-140 V MatE
COJEOIIM_00640 1.6e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COJEOIIM_00641 5e-87 S Alpha beta hydrolase
COJEOIIM_00642 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COJEOIIM_00643 2.5e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
COJEOIIM_00644 4.6e-112 argE 3.5.1.18 E Peptidase dimerisation domain
COJEOIIM_00645 5e-102 IQ Enoyl-(Acyl carrier protein) reductase
COJEOIIM_00646 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
COJEOIIM_00647 4.3e-54 queT S QueT transporter
COJEOIIM_00649 7.3e-65 degV S Uncharacterised protein, DegV family COG1307
COJEOIIM_00650 2e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COJEOIIM_00651 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COJEOIIM_00652 1.9e-34 trxA O Belongs to the thioredoxin family
COJEOIIM_00653 4.9e-87 S Sucrose-6F-phosphate phosphohydrolase
COJEOIIM_00654 3.2e-121 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COJEOIIM_00655 2.8e-49 S Threonine/Serine exporter, ThrE
COJEOIIM_00656 1.3e-81 thrE S Putative threonine/serine exporter
COJEOIIM_00657 3.1e-27 cspC K Cold shock protein
COJEOIIM_00658 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
COJEOIIM_00659 2.9e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
COJEOIIM_00660 5.4e-23
COJEOIIM_00661 1.2e-58 3.6.1.27 I phosphatase
COJEOIIM_00662 3.1e-25
COJEOIIM_00663 2.4e-65 I alpha/beta hydrolase fold
COJEOIIM_00664 1.3e-38 azlD S branched-chain amino acid
COJEOIIM_00665 1.1e-104 azlC E AzlC protein
COJEOIIM_00666 1.6e-17
COJEOIIM_00667 1.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
COJEOIIM_00668 3.8e-99 V domain protein
COJEOIIM_00669 3.9e-10
COJEOIIM_00673 1.9e-130 M Glycosyl hydrolases family 25
COJEOIIM_00680 1.4e-27 S Calcineurin-like phosphoesterase
COJEOIIM_00682 8e-119 rny D peptidase
COJEOIIM_00683 2.1e-77 S Phage tail protein
COJEOIIM_00684 8.5e-288 M Phage tail tape measure protein TP901
COJEOIIM_00686 1.1e-15 S Phage tail assembly chaperone proteins, TAC
COJEOIIM_00687 3.5e-78 S Phage tail tube protein
COJEOIIM_00688 7.8e-56 S Protein of unknown function (DUF806)
COJEOIIM_00689 4.8e-54 S Bacteriophage HK97-gp10, putative tail-component
COJEOIIM_00690 1.4e-51 S Phage head-tail joining protein
COJEOIIM_00691 3.7e-22 S Phage gp6-like head-tail connector protein
COJEOIIM_00692 1.2e-195 S Phage capsid family
COJEOIIM_00693 9.1e-114 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
COJEOIIM_00694 1.1e-193 S Phage portal protein
COJEOIIM_00696 0.0 S Phage Terminase
COJEOIIM_00697 4.3e-83 L Phage terminase, small subunit
COJEOIIM_00698 1.1e-71 L HNH nucleases
COJEOIIM_00700 6.1e-55 V Abi-like protein
COJEOIIM_00701 6.4e-33 arpU S Phage transcriptional regulator, ArpU family
COJEOIIM_00710 9.4e-66
COJEOIIM_00711 1.2e-25
COJEOIIM_00714 9.3e-29 L N-terminal phage replisome organiser (Phage_rep_org_N)
COJEOIIM_00715 2.4e-53 S Putative HNHc nuclease
COJEOIIM_00719 1.7e-83 ps308 K AntA/AntB antirepressor
COJEOIIM_00720 3.8e-09 XK27_07105 K Helix-turn-helix XRE-family like proteins
COJEOIIM_00721 9.1e-37 K Helix-turn-helix XRE-family like proteins
COJEOIIM_00722 1.9e-37 E Zn peptidase
COJEOIIM_00724 2.3e-48 polC 2.7.7.7 L DNA polymerase III
COJEOIIM_00726 1e-09
COJEOIIM_00727 4.7e-76
COJEOIIM_00730 2.1e-88 sip L Belongs to the 'phage' integrase family
COJEOIIM_00731 3.5e-22 S PIN domain
COJEOIIM_00732 2.6e-11 D Antitoxin component of a toxin-antitoxin (TA) module
COJEOIIM_00733 2.2e-83 pspA D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
COJEOIIM_00734 5.3e-56 Z012_06740 S Fic/DOC family
COJEOIIM_00735 1.6e-28
COJEOIIM_00736 1.2e-61 gepA K Protein of unknown function (DUF4065)
COJEOIIM_00737 7.5e-08
COJEOIIM_00738 5.7e-66 D nuclear chromosome segregation
COJEOIIM_00740 4.8e-78 S Fic/DOC family
COJEOIIM_00742 1e-10
COJEOIIM_00745 1.8e-58 ruvB 3.6.4.12 L four-way junction helicase activity
COJEOIIM_00749 1.9e-11 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
COJEOIIM_00750 7.5e-20
COJEOIIM_00755 1.5e-08
COJEOIIM_00760 1e-20 S Replication initiator protein A (RepA) N-terminus
COJEOIIM_00762 1.4e-09 S Arc-like DNA binding domain
COJEOIIM_00767 1.7e-11 3.4.21.88 K Peptidase S24-like
COJEOIIM_00768 2.2e-11 S sequence-specific DNA binding
COJEOIIM_00769 5.1e-86 S Fic/DOC family
COJEOIIM_00772 5.8e-198 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
COJEOIIM_00773 3.5e-82 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COJEOIIM_00774 4.1e-177 thrC 4.2.3.1 E Threonine synthase
COJEOIIM_00775 2.4e-128 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COJEOIIM_00776 5.2e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
COJEOIIM_00777 5.6e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
COJEOIIM_00778 5e-57 S peptidoglycan catabolic process
COJEOIIM_00779 1.5e-194 XK27_08315 M Sulfatase
COJEOIIM_00781 6.4e-168 mdtG EGP Major facilitator Superfamily
COJEOIIM_00782 6.3e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
COJEOIIM_00783 5.7e-84 treR K UTRA
COJEOIIM_00784 3.3e-259 treB G phosphotransferase system
COJEOIIM_00785 3.5e-63 3.1.3.73 G phosphoglycerate mutase
COJEOIIM_00786 2.4e-82 pncA Q isochorismatase
COJEOIIM_00787 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
COJEOIIM_00788 1.2e-103 ydhQ K UbiC transcription regulator-associated domain protein
COJEOIIM_00789 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COJEOIIM_00790 3.6e-41 K Transcriptional regulator, HxlR family
COJEOIIM_00791 8.3e-164 C Luciferase-like monooxygenase
COJEOIIM_00793 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COJEOIIM_00794 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
COJEOIIM_00795 9.7e-194 cycA E Amino acid permease
COJEOIIM_00796 8.3e-187 ytgP S Polysaccharide biosynthesis protein
COJEOIIM_00797 1.1e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COJEOIIM_00798 1.2e-80 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COJEOIIM_00799 5.1e-193 pepV 3.5.1.18 E dipeptidase PepV
COJEOIIM_00800 3.3e-182 S Protein of unknown function DUF262
COJEOIIM_00802 3e-36
COJEOIIM_00803 1.3e-65 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COJEOIIM_00804 4.2e-61 marR K Transcriptional regulator, MarR family
COJEOIIM_00805 6.4e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COJEOIIM_00806 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COJEOIIM_00807 6.5e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
COJEOIIM_00808 1.4e-98 IQ reductase
COJEOIIM_00809 1.8e-194 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
COJEOIIM_00810 7.9e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
COJEOIIM_00811 1.5e-63 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COJEOIIM_00812 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
COJEOIIM_00813 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COJEOIIM_00814 2.3e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
COJEOIIM_00815 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
COJEOIIM_00816 1.5e-230 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COJEOIIM_00817 9.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
COJEOIIM_00818 2.7e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COJEOIIM_00819 5.7e-119 gla U Major intrinsic protein
COJEOIIM_00820 1.5e-45 ykuL S CBS domain
COJEOIIM_00821 1.5e-60 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
COJEOIIM_00822 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
COJEOIIM_00823 2.1e-88 ykuT M mechanosensitive ion channel
COJEOIIM_00825 1e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
COJEOIIM_00826 2e-21 yheA S Belongs to the UPF0342 family
COJEOIIM_00827 3.9e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
COJEOIIM_00828 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COJEOIIM_00830 5.4e-53 hit FG histidine triad
COJEOIIM_00831 2.8e-94 ecsA V ABC transporter, ATP-binding protein
COJEOIIM_00832 1.3e-72 ecsB U ABC transporter
COJEOIIM_00833 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
COJEOIIM_00834 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COJEOIIM_00835 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
COJEOIIM_00836 6.8e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COJEOIIM_00837 9e-240 sftA D Belongs to the FtsK SpoIIIE SftA family
COJEOIIM_00838 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
COJEOIIM_00839 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
COJEOIIM_00840 6.7e-69 ybhL S Belongs to the BI1 family
COJEOIIM_00841 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COJEOIIM_00842 9.5e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COJEOIIM_00843 2.1e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COJEOIIM_00844 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COJEOIIM_00845 1.6e-79 dnaB L replication initiation and membrane attachment
COJEOIIM_00846 2.2e-107 dnaI L Primosomal protein DnaI
COJEOIIM_00847 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COJEOIIM_00848 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COJEOIIM_00849 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
COJEOIIM_00850 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COJEOIIM_00851 2.5e-71 yqeG S HAD phosphatase, family IIIA
COJEOIIM_00852 7.9e-181 yqeH S Ribosome biogenesis GTPase YqeH
COJEOIIM_00853 1e-29 yhbY J RNA-binding protein
COJEOIIM_00854 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COJEOIIM_00855 7.2e-72 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
COJEOIIM_00856 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COJEOIIM_00857 4.2e-82 H Nodulation protein S (NodS)
COJEOIIM_00858 1.3e-122 ylbM S Belongs to the UPF0348 family
COJEOIIM_00859 2e-57 yceD S Uncharacterized ACR, COG1399
COJEOIIM_00860 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
COJEOIIM_00861 1.2e-88 plsC 2.3.1.51 I Acyltransferase
COJEOIIM_00862 1.1e-93 yabB 2.1.1.223 L Methyltransferase small domain
COJEOIIM_00863 1.5e-27 yazA L GIY-YIG catalytic domain protein
COJEOIIM_00864 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
COJEOIIM_00865 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COJEOIIM_00866 6.9e-37
COJEOIIM_00867 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
COJEOIIM_00868 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COJEOIIM_00869 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COJEOIIM_00870 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COJEOIIM_00871 8.6e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COJEOIIM_00873 3.1e-111 K response regulator
COJEOIIM_00874 5e-167 arlS 2.7.13.3 T Histidine kinase
COJEOIIM_00875 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COJEOIIM_00876 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
COJEOIIM_00877 5.6e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
COJEOIIM_00878 7.3e-105
COJEOIIM_00879 7.2e-117
COJEOIIM_00880 1.3e-41 dut S dUTPase
COJEOIIM_00881 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COJEOIIM_00882 3.7e-46 yqhY S Asp23 family, cell envelope-related function
COJEOIIM_00883 1.9e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COJEOIIM_00884 1.7e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COJEOIIM_00885 1.2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COJEOIIM_00886 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COJEOIIM_00887 4.7e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COJEOIIM_00888 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
COJEOIIM_00889 6.6e-49 argR K Regulates arginine biosynthesis genes
COJEOIIM_00890 4.2e-178 recN L May be involved in recombinational repair of damaged DNA
COJEOIIM_00891 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COJEOIIM_00892 2.2e-30 ynzC S UPF0291 protein
COJEOIIM_00893 5.9e-27 yneF S UPF0154 protein
COJEOIIM_00894 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
COJEOIIM_00895 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
COJEOIIM_00896 1.2e-74 yciQ P membrane protein (DUF2207)
COJEOIIM_00897 3e-19 D nuclear chromosome segregation
COJEOIIM_00898 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COJEOIIM_00899 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COJEOIIM_00900 7.4e-70 gluP 3.4.21.105 S Peptidase, S54 family
COJEOIIM_00901 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
COJEOIIM_00902 1.1e-157 glk 2.7.1.2 G Glucokinase
COJEOIIM_00903 2.7e-46 yqhL P Rhodanese-like protein
COJEOIIM_00904 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
COJEOIIM_00905 1.9e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COJEOIIM_00906 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
COJEOIIM_00907 1.3e-45 glnR K Transcriptional regulator
COJEOIIM_00908 2e-247 glnA 6.3.1.2 E glutamine synthetase
COJEOIIM_00910 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
COJEOIIM_00911 2.7e-48 S Domain of unknown function (DUF956)
COJEOIIM_00912 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
COJEOIIM_00913 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COJEOIIM_00914 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COJEOIIM_00915 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
COJEOIIM_00916 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
COJEOIIM_00917 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COJEOIIM_00918 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COJEOIIM_00919 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
COJEOIIM_00920 4.8e-170 nusA K Participates in both transcription termination and antitermination
COJEOIIM_00921 1.4e-39 ylxR K Protein of unknown function (DUF448)
COJEOIIM_00922 6.9e-26 ylxQ J ribosomal protein
COJEOIIM_00923 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COJEOIIM_00924 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COJEOIIM_00925 1.8e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COJEOIIM_00926 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
COJEOIIM_00927 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COJEOIIM_00928 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COJEOIIM_00929 7.7e-274 dnaK O Heat shock 70 kDa protein
COJEOIIM_00930 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COJEOIIM_00931 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COJEOIIM_00933 9.2e-206 glnP P ABC transporter
COJEOIIM_00934 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COJEOIIM_00935 1.5e-31
COJEOIIM_00936 2e-111 ampC V Beta-lactamase
COJEOIIM_00937 3.5e-110 cobQ S glutamine amidotransferase
COJEOIIM_00938 3.6e-220 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
COJEOIIM_00939 6.8e-86 tdk 2.7.1.21 F thymidine kinase
COJEOIIM_00940 2.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COJEOIIM_00941 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COJEOIIM_00942 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COJEOIIM_00943 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COJEOIIM_00944 1.9e-95 atpB C it plays a direct role in the translocation of protons across the membrane
COJEOIIM_00945 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COJEOIIM_00946 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COJEOIIM_00947 2.7e-57 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COJEOIIM_00948 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COJEOIIM_00949 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COJEOIIM_00950 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COJEOIIM_00951 3.9e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
COJEOIIM_00952 4.1e-15 ywzB S Protein of unknown function (DUF1146)
COJEOIIM_00953 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COJEOIIM_00954 3.4e-167 mbl D Cell shape determining protein MreB Mrl
COJEOIIM_00955 1.2e-26 yidD S Could be involved in insertion of integral membrane proteins into the membrane
COJEOIIM_00956 1.8e-12 S Protein of unknown function (DUF2969)
COJEOIIM_00957 6.1e-187 rodA D Belongs to the SEDS family
COJEOIIM_00958 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
COJEOIIM_00959 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
COJEOIIM_00960 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
COJEOIIM_00961 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COJEOIIM_00962 4.4e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COJEOIIM_00963 2.4e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COJEOIIM_00964 5.8e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COJEOIIM_00965 9.8e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COJEOIIM_00966 3.3e-90 stp 3.1.3.16 T phosphatase
COJEOIIM_00967 3.4e-191 KLT serine threonine protein kinase
COJEOIIM_00968 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COJEOIIM_00969 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
COJEOIIM_00970 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
COJEOIIM_00971 4.5e-53 asp S Asp23 family, cell envelope-related function
COJEOIIM_00972 2.8e-238 yloV S DAK2 domain fusion protein YloV
COJEOIIM_00973 3.3e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COJEOIIM_00974 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COJEOIIM_00975 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COJEOIIM_00976 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COJEOIIM_00977 4.7e-211 smc D Required for chromosome condensation and partitioning
COJEOIIM_00978 9.1e-149 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COJEOIIM_00979 7e-40 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COJEOIIM_00980 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COJEOIIM_00981 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
COJEOIIM_00982 1.1e-26 ylqC S Belongs to the UPF0109 family
COJEOIIM_00983 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COJEOIIM_00984 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
COJEOIIM_00985 5.7e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
COJEOIIM_00986 7e-198 yfnA E amino acid
COJEOIIM_00987 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COJEOIIM_00988 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
COJEOIIM_00989 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COJEOIIM_00990 5.3e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COJEOIIM_00991 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COJEOIIM_00992 5.6e-20 S Tetratricopeptide repeat
COJEOIIM_00993 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COJEOIIM_00994 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COJEOIIM_00995 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COJEOIIM_00996 2.3e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COJEOIIM_00997 1.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COJEOIIM_00998 5e-23 ykzG S Belongs to the UPF0356 family
COJEOIIM_00999 1.6e-24
COJEOIIM_01000 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COJEOIIM_01001 3.7e-32 1.1.1.27 C L-malate dehydrogenase activity
COJEOIIM_01002 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
COJEOIIM_01003 0.0 typA T GTP-binding protein TypA
COJEOIIM_01004 6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
COJEOIIM_01005 7e-115 manY G PTS system
COJEOIIM_01006 3.3e-148 manN G system, mannose fructose sorbose family IID component
COJEOIIM_01007 1.6e-102 ftsW D Belongs to the SEDS family
COJEOIIM_01008 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
COJEOIIM_01009 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
COJEOIIM_01010 7.2e-74 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
COJEOIIM_01011 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COJEOIIM_01012 2.4e-131 ylbL T Belongs to the peptidase S16 family
COJEOIIM_01013 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
COJEOIIM_01014 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COJEOIIM_01015 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COJEOIIM_01016 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COJEOIIM_01017 5.2e-225 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COJEOIIM_01018 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
COJEOIIM_01019 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COJEOIIM_01020 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
COJEOIIM_01021 3e-152 purD 6.3.4.13 F Belongs to the GARS family
COJEOIIM_01022 1.5e-93 S Acyltransferase family
COJEOIIM_01023 2.2e-194 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COJEOIIM_01024 3.9e-122 K LysR substrate binding domain
COJEOIIM_01026 2.2e-20
COJEOIIM_01027 6.2e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
COJEOIIM_01028 5.8e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
COJEOIIM_01029 1.4e-50 comEA L Competence protein ComEA
COJEOIIM_01030 2e-69 comEB 3.5.4.12 F ComE operon protein 2
COJEOIIM_01031 1.4e-155 comEC S Competence protein ComEC
COJEOIIM_01032 9.3e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
COJEOIIM_01033 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
COJEOIIM_01034 3e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
COJEOIIM_01035 2.8e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
COJEOIIM_01036 8.1e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
COJEOIIM_01037 1.5e-228 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
COJEOIIM_01038 1.8e-36 ypmB S Protein conserved in bacteria
COJEOIIM_01039 4e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
COJEOIIM_01040 1e-235 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
COJEOIIM_01041 5.1e-56 dnaD L DnaD domain protein
COJEOIIM_01042 1.1e-81 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COJEOIIM_01043 9.9e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COJEOIIM_01044 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COJEOIIM_01045 1.9e-93 M transferase activity, transferring glycosyl groups
COJEOIIM_01046 1.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
COJEOIIM_01047 1.3e-99 epsJ1 M Glycosyltransferase like family 2
COJEOIIM_01050 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
COJEOIIM_01051 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
COJEOIIM_01052 5.4e-56 yqeY S YqeY-like protein
COJEOIIM_01054 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
COJEOIIM_01055 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COJEOIIM_01056 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COJEOIIM_01057 6.6e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
COJEOIIM_01058 2.9e-276 yfmR S ABC transporter, ATP-binding protein
COJEOIIM_01059 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COJEOIIM_01060 9.4e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COJEOIIM_01061 8.6e-135 yvgN C Aldo keto reductase
COJEOIIM_01062 2.4e-35 K helix_turn_helix, mercury resistance
COJEOIIM_01063 1.3e-102 S Aldo keto reductase
COJEOIIM_01065 7.2e-79 ypmR E GDSL-like Lipase/Acylhydrolase
COJEOIIM_01066 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
COJEOIIM_01067 3.6e-24 yozE S Belongs to the UPF0346 family
COJEOIIM_01068 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COJEOIIM_01069 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COJEOIIM_01070 6.2e-85 dprA LU DNA protecting protein DprA
COJEOIIM_01071 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COJEOIIM_01072 9.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
COJEOIIM_01073 5.8e-205 G PTS system Galactitol-specific IIC component
COJEOIIM_01074 2.3e-81 K Bacterial regulatory proteins, tetR family
COJEOIIM_01075 3.3e-129 yjjC V ATPases associated with a variety of cellular activities
COJEOIIM_01076 1.1e-202 M Exporter of polyketide antibiotics
COJEOIIM_01077 4e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
COJEOIIM_01078 2.3e-34 S Repeat protein
COJEOIIM_01079 5.8e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COJEOIIM_01081 1.7e-15
COJEOIIM_01084 5.9e-87 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COJEOIIM_01085 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
COJEOIIM_01086 9.1e-43 yodB K Transcriptional regulator, HxlR family
COJEOIIM_01087 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COJEOIIM_01088 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COJEOIIM_01089 9.3e-129 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
COJEOIIM_01090 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
COJEOIIM_01091 2.2e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COJEOIIM_01092 3.4e-65 sbcC L Putative exonuclease SbcCD, C subunit
COJEOIIM_01093 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
COJEOIIM_01094 7.2e-53 perR P Belongs to the Fur family
COJEOIIM_01095 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COJEOIIM_01096 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COJEOIIM_01097 2.5e-86 S (CBS) domain
COJEOIIM_01098 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COJEOIIM_01099 2.2e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COJEOIIM_01100 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COJEOIIM_01101 2.8e-139 yabM S Polysaccharide biosynthesis protein
COJEOIIM_01102 3.6e-31 yabO J S4 domain protein
COJEOIIM_01103 1e-21 divIC D Septum formation initiator
COJEOIIM_01104 1.1e-40 yabR J RNA binding
COJEOIIM_01105 1.9e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COJEOIIM_01106 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COJEOIIM_01107 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COJEOIIM_01108 7.8e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COJEOIIM_01109 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COJEOIIM_01110 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
COJEOIIM_01115 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
COJEOIIM_01116 1.4e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COJEOIIM_01117 3.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COJEOIIM_01118 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
COJEOIIM_01119 2.5e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COJEOIIM_01121 1.6e-55 ctsR K Belongs to the CtsR family
COJEOIIM_01122 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COJEOIIM_01123 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COJEOIIM_01124 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COJEOIIM_01126 1.5e-13
COJEOIIM_01127 1e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COJEOIIM_01128 1.3e-158 ccpA K catabolite control protein A
COJEOIIM_01129 1.5e-29 S VanZ like family
COJEOIIM_01130 1.5e-119 yebC K Transcriptional regulatory protein
COJEOIIM_01131 2.1e-102 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COJEOIIM_01132 4.7e-121 comGA NU Type II IV secretion system protein
COJEOIIM_01133 5.7e-98 comGB NU type II secretion system
COJEOIIM_01134 1.2e-27 comGC U competence protein ComGC
COJEOIIM_01135 1.5e-13
COJEOIIM_01137 5.5e-11 S Putative Competence protein ComGF
COJEOIIM_01139 7.6e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
COJEOIIM_01140 9.3e-184 cycA E Amino acid permease
COJEOIIM_01141 3e-57 S Calcineurin-like phosphoesterase
COJEOIIM_01142 1.9e-53 yutD S Protein of unknown function (DUF1027)
COJEOIIM_01143 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
COJEOIIM_01144 7.8e-32 S Protein of unknown function (DUF1461)
COJEOIIM_01145 3e-92 dedA S SNARE associated Golgi protein
COJEOIIM_01146 2.7e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
COJEOIIM_01147 8.8e-50 yugI 5.3.1.9 J general stress protein
COJEOIIM_01148 8.5e-89 2.7.7.65 T phosphorelay sensor kinase activity
COJEOIIM_01149 1.3e-132 cbiQ P Cobalt transport protein
COJEOIIM_01150 4.6e-157 P ABC transporter
COJEOIIM_01151 1.2e-149 cbiO2 P ABC transporter
COJEOIIM_01152 2.5e-101 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
COJEOIIM_01153 1.1e-107
COJEOIIM_01154 3.5e-40 S RelB antitoxin
COJEOIIM_01155 4e-44
COJEOIIM_01157 4.1e-98 norB EGP Major Facilitator
COJEOIIM_01158 1.5e-103 tag 3.2.2.20 L Methyladenine glycosylase
COJEOIIM_01159 1.8e-235 stp_1 EGP Major facilitator Superfamily
COJEOIIM_01160 2.4e-71 H ThiF family
COJEOIIM_01161 6.3e-207 arsR K DNA-binding transcription factor activity
COJEOIIM_01162 6.2e-97 K Transcriptional regulator
COJEOIIM_01163 2.7e-23 L Transposase
COJEOIIM_01164 2.8e-79 L Transposase and inactivated derivatives IS30 family
COJEOIIM_01165 6.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
COJEOIIM_01166 9.8e-135 K Transcriptional regulator
COJEOIIM_01167 2.3e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COJEOIIM_01168 1.5e-84 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
COJEOIIM_01169 5.9e-192 carB 6.3.5.5 F Carbamoyl-phosphate synthase
COJEOIIM_01170 4.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COJEOIIM_01171 2.7e-204 pyrP F Permease
COJEOIIM_01172 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COJEOIIM_01173 7.3e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COJEOIIM_01174 6.8e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COJEOIIM_01175 6.7e-57 3.1.3.18 J HAD-hyrolase-like
COJEOIIM_01176 1.7e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COJEOIIM_01177 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COJEOIIM_01178 3.1e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
COJEOIIM_01179 5.8e-118 prmA J Ribosomal protein L11 methyltransferase
COJEOIIM_01180 7.6e-43 XK27_03960 S Protein of unknown function (DUF3013)
COJEOIIM_01181 1.5e-143 iunH2 3.2.2.1 F nucleoside hydrolase
COJEOIIM_01182 6.4e-12
COJEOIIM_01184 5.9e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COJEOIIM_01185 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
COJEOIIM_01186 5.2e-65 hly S protein, hemolysin III
COJEOIIM_01187 7.3e-41 M1-874 K Domain of unknown function (DUF1836)
COJEOIIM_01188 9.4e-84 S membrane
COJEOIIM_01189 1.1e-79 S VIT family
COJEOIIM_01190 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
COJEOIIM_01191 7.9e-56 P Plays a role in the regulation of phosphate uptake
COJEOIIM_01192 1.8e-115 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COJEOIIM_01193 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COJEOIIM_01194 3e-122 pstA P Phosphate transport system permease protein PstA
COJEOIIM_01195 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
COJEOIIM_01196 3.2e-97 pstS P Phosphate
COJEOIIM_01197 1.3e-41 yjbH Q Thioredoxin
COJEOIIM_01198 1.5e-232 pepF E oligoendopeptidase F
COJEOIIM_01199 1.1e-68 coiA 3.6.4.12 S Competence protein
COJEOIIM_01200 2.1e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
COJEOIIM_01201 1.4e-218 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
COJEOIIM_01203 6.3e-85 yxeH S hydrolase
COJEOIIM_01204 9e-114 K response regulator
COJEOIIM_01205 1.1e-272 vicK 2.7.13.3 T Histidine kinase
COJEOIIM_01206 4.6e-103 yycH S YycH protein
COJEOIIM_01207 2.8e-79 yycI S YycH protein
COJEOIIM_01208 1.8e-30 yyaQ S YjbR
COJEOIIM_01209 1.3e-116 vicX 3.1.26.11 S domain protein
COJEOIIM_01210 3.7e-145 htrA 3.4.21.107 O serine protease
COJEOIIM_01211 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COJEOIIM_01212 4.4e-40 1.6.5.2 GM NAD(P)H-binding
COJEOIIM_01213 3.3e-25 K MarR family transcriptional regulator
COJEOIIM_01214 5.9e-88 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
COJEOIIM_01215 8.5e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COJEOIIM_01216 4.2e-208 G glycerol-3-phosphate transporter
COJEOIIM_01217 5.9e-30 L Helix-turn-helix domain
COJEOIIM_01218 3.6e-69 L HTH-like domain
COJEOIIM_01219 2.1e-71 L PFAM transposase IS200-family protein
COJEOIIM_01220 7.2e-149 mepA V MATE efflux family protein
COJEOIIM_01221 4.3e-150 lsa S ABC transporter
COJEOIIM_01222 5.2e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COJEOIIM_01223 8e-110 puuD S peptidase C26
COJEOIIM_01224 2.9e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
COJEOIIM_01225 1.1e-25
COJEOIIM_01226 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
COJEOIIM_01227 6.6e-60 uspA T Universal stress protein family
COJEOIIM_01229 2.5e-211 glnP P ABC transporter
COJEOIIM_01230 9.3e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
COJEOIIM_01231 1.6e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
COJEOIIM_01232 2.8e-81 S Belongs to the UPF0246 family
COJEOIIM_01233 5.6e-10 S CAAX protease self-immunity
COJEOIIM_01234 3.5e-59 ykhA 3.1.2.20 I Thioesterase superfamily
COJEOIIM_01235 8.7e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COJEOIIM_01237 1.6e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COJEOIIM_01238 5.3e-64 C FMN binding
COJEOIIM_01239 1.3e-204 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
COJEOIIM_01240 1.7e-54 rplI J Binds to the 23S rRNA
COJEOIIM_01241 3.9e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
COJEOIIM_01242 4.7e-07
COJEOIIM_01244 3.5e-132 ABC-SBP S ABC transporter
COJEOIIM_01245 3.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
COJEOIIM_01246 6.7e-107 XK27_08845 S ABC transporter, ATP-binding protein
COJEOIIM_01247 2.8e-66 M ErfK YbiS YcfS YnhG
COJEOIIM_01248 1.2e-53 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COJEOIIM_01249 4.2e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COJEOIIM_01250 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COJEOIIM_01251 1.2e-102 pgm3 G phosphoglycerate mutase
COJEOIIM_01252 4.7e-56 S CAAX protease self-immunity
COJEOIIM_01253 2.2e-47 C Flavodoxin
COJEOIIM_01254 9.7e-60 yphH S Cupin domain
COJEOIIM_01255 3.6e-46 yphJ 4.1.1.44 S decarboxylase
COJEOIIM_01257 4.5e-20 L T/G mismatch-specific endonuclease activity
COJEOIIM_01258 2.3e-125 L T/G mismatch-specific endonuclease activity
COJEOIIM_01260 6.6e-60 hsdM 2.1.1.72 V type I restriction-modification system
COJEOIIM_01261 5.6e-18 3.1.21.3 V Type I restriction modification DNA specificity domain
COJEOIIM_01262 1.2e-105 L Belongs to the 'phage' integrase family
COJEOIIM_01263 6.1e-11 L Plasmid pRiA4b ORF-3-like protein
COJEOIIM_01264 1.1e-189 XK27_11280 S Psort location CytoplasmicMembrane, score
COJEOIIM_01266 1.5e-109 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
COJEOIIM_01267 1.8e-218 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
COJEOIIM_01268 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
COJEOIIM_01269 1.7e-215 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
COJEOIIM_01270 1.5e-188 iolF EGP Major facilitator Superfamily
COJEOIIM_01271 2.2e-76 rhaR K helix_turn_helix, arabinose operon control protein
COJEOIIM_01272 6.4e-50 S Membrane
COJEOIIM_01273 1.3e-180 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
COJEOIIM_01274 3e-56 S COG NOG19168 non supervised orthologous group
COJEOIIM_01276 7.2e-58 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
COJEOIIM_01277 4.6e-18 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
COJEOIIM_01278 3.9e-68 tra L EVIDENCE BY HOMOLOGY BIO14.04 Transposon related functions. BELONGS TO THE IS30 FAMILY OF TRANSPOSASE. There are 15 such elements in the chromosome
COJEOIIM_01279 4.7e-35 L Helix-turn-helix domain
COJEOIIM_01280 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
COJEOIIM_01281 8.3e-149 yedE S Sulphur transport
COJEOIIM_01282 9.2e-101 selD 2.7.9.3 E AIR synthase related protein, C-terminal domain
COJEOIIM_01283 2.4e-176 rnfC C RnfC Barrel sandwich hybrid domain
COJEOIIM_01284 9e-29 yitW S Iron-sulfur cluster assembly protein
COJEOIIM_01285 2e-109 selA 2.9.1.1 J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
COJEOIIM_01286 5.1e-111 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
COJEOIIM_01287 4.8e-138 selB J Elongation factor SelB, winged helix
COJEOIIM_01288 4.5e-08 S Protein of unknown function (DUF3343)
COJEOIIM_01289 1.2e-48 yedF O Belongs to the sulfur carrier protein TusA family
COJEOIIM_01290 7e-223 ybeC E amino acid
COJEOIIM_01291 4.4e-94 XK27_00825 S Sulfite exporter TauE/SafE
COJEOIIM_01292 7e-144 5.1.1.4 E Proline racemase
COJEOIIM_01293 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
COJEOIIM_01294 1.6e-73 prdD S An automated process has identified a potential problem with this gene model
COJEOIIM_01295 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
COJEOIIM_01296 7.6e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
COJEOIIM_01297 7.1e-26 S Psort location Cytoplasmic, score
COJEOIIM_01298 4.3e-235 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
COJEOIIM_01300 2.2e-116 ynjE 2.8.1.11 P Rhodanese Homology Domain
COJEOIIM_01301 1.6e-16 yeeD O Belongs to the sulfur carrier protein TusA family
COJEOIIM_01302 1.1e-62 yeeE S Sulphur transport
COJEOIIM_01303 3.9e-105 yraQ S Predicted permease
COJEOIIM_01304 6.7e-124 yvgN C Aldo keto reductase
COJEOIIM_01308 3.4e-16
COJEOIIM_01309 3.6e-09
COJEOIIM_01313 9.8e-21 M domain protein
COJEOIIM_01314 1.3e-35 agrA KT Response regulator of the LytR AlgR family
COJEOIIM_01315 2.1e-44 2.7.13.3 T protein histidine kinase activity
COJEOIIM_01316 0.0 pepN 3.4.11.2 E aminopeptidase
COJEOIIM_01317 6.9e-08 S CAAX protease self-immunity
COJEOIIM_01318 1.8e-33
COJEOIIM_01320 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
COJEOIIM_01321 2.1e-64 licT K transcriptional antiterminator
COJEOIIM_01322 6e-205 G Pts system
COJEOIIM_01323 5.9e-173 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COJEOIIM_01324 3.9e-38 S Replication initiator protein A (RepA) N-terminus
COJEOIIM_01325 9.4e-109 L Initiator Replication protein
COJEOIIM_01326 1.9e-09 yokH G regulation of fungal-type cell wall biogenesis
COJEOIIM_01327 8.3e-47 S Fic/DOC family
COJEOIIM_01328 3.1e-11 S Fic/DOC family
COJEOIIM_01329 9.4e-41 S Fic/DOC family
COJEOIIM_01330 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
COJEOIIM_01331 2.2e-60 K DeoR C terminal sensor domain
COJEOIIM_01332 2.7e-39 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
COJEOIIM_01333 2e-35 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
COJEOIIM_01334 2.4e-181 gatC G PTS system sugar-specific permease component
COJEOIIM_01335 2.8e-119 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
COJEOIIM_01336 1.1e-166 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
COJEOIIM_01337 7.8e-88 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
COJEOIIM_01338 1.1e-278 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
COJEOIIM_01339 1e-231 tetP J elongation factor G
COJEOIIM_01340 1.2e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COJEOIIM_01342 3.1e-217 yjeM E Amino Acid
COJEOIIM_01343 3.5e-61 yphA GM NAD dependent epimerase/dehydratase family
COJEOIIM_01344 7.8e-77 K Helix-turn-helix domain, rpiR family
COJEOIIM_01345 1.2e-91 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
COJEOIIM_01346 3.3e-126 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
COJEOIIM_01347 1.2e-88 nanK GK ROK family
COJEOIIM_01348 3.8e-54 ndk 2.7.4.6 F Belongs to the NDK family
COJEOIIM_01349 2.3e-64 G Xylose isomerase domain protein TIM barrel
COJEOIIM_01350 3.9e-154 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
COJEOIIM_01351 6.6e-207 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COJEOIIM_01352 1.5e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
COJEOIIM_01353 5.5e-113 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
COJEOIIM_01354 7.7e-41 S Iron-sulfur cluster assembly protein
COJEOIIM_01355 1.3e-66 S Protein of unknown function (DUF1440)
COJEOIIM_01356 6.5e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
COJEOIIM_01357 7.8e-187 mtnE 2.6.1.83 E Aminotransferase
COJEOIIM_01359 2.3e-14
COJEOIIM_01360 4.2e-37 blpT
COJEOIIM_01361 4.2e-08
COJEOIIM_01363 1.2e-12
COJEOIIM_01364 1.1e-16
COJEOIIM_01369 5.2e-59 2.7.13.3 T GHKL domain
COJEOIIM_01370 1.9e-56 K LytTr DNA-binding domain
COJEOIIM_01378 4e-282 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
COJEOIIM_01379 2e-86 mesE M Transport protein ComB
COJEOIIM_01382 1.9e-70 xerD L Phage integrase, N-terminal SAM-like domain
COJEOIIM_01383 1.4e-265 fbp 3.1.3.11 G phosphatase activity
COJEOIIM_01384 1.6e-189 tonB M YSIRK type signal peptide
COJEOIIM_01385 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
COJEOIIM_01386 3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
COJEOIIM_01387 4.7e-163 ytbD EGP Major facilitator Superfamily
COJEOIIM_01388 4e-110 IQ NAD dependent epimerase/dehydratase family
COJEOIIM_01389 5.8e-104 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
COJEOIIM_01390 4.5e-43 gutM K Glucitol operon activator protein (GutM)
COJEOIIM_01391 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
COJEOIIM_01392 1.4e-136 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
COJEOIIM_01393 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
COJEOIIM_01394 9.1e-63 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
COJEOIIM_01395 5.5e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
COJEOIIM_01396 2.5e-136 pfoS S Phosphotransferase system, EIIC
COJEOIIM_01398 2.6e-207 spaB S Lantibiotic dehydratase, C terminus
COJEOIIM_01399 4.3e-184 spaT V ATPases associated with a variety of cellular activities
COJEOIIM_01400 1.4e-58 spaC2 V Lanthionine synthetase C-like protein
COJEOIIM_01401 8.8e-90 KT Transcriptional regulatory protein, C terminal
COJEOIIM_01402 1.7e-105 2.7.13.3 T His Kinase A (phosphoacceptor) domain
COJEOIIM_01403 3.3e-73 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
COJEOIIM_01404 9.6e-47 V ABC-2 family transporter protein
COJEOIIM_01406 2.5e-27 K Helix-turn-helix XRE-family like proteins
COJEOIIM_01407 7.7e-20 S protein encoded in hypervariable junctions of pilus gene clusters
COJEOIIM_01409 3.2e-223 E ABC transporter, substratebinding protein
COJEOIIM_01410 1.8e-115 sufC O FeS assembly ATPase SufC
COJEOIIM_01411 5.6e-143 sufD O FeS assembly protein SufD
COJEOIIM_01412 3.3e-148 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COJEOIIM_01413 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
COJEOIIM_01414 9.4e-240 sufB O assembly protein SufB
COJEOIIM_01415 3.3e-45 S VIT family
COJEOIIM_01416 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
COJEOIIM_01417 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COJEOIIM_01418 2.1e-112 rssA S Phospholipase, patatin family
COJEOIIM_01419 8.2e-16
COJEOIIM_01421 1.9e-39
COJEOIIM_01422 7.8e-38 K transcriptional regulator PadR family
COJEOIIM_01423 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
COJEOIIM_01424 1.2e-15 S Putative adhesin
COJEOIIM_01425 2.2e-16 pspC KT PspC domain
COJEOIIM_01427 5.1e-13 S Enterocin A Immunity
COJEOIIM_01428 4e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COJEOIIM_01429 1.3e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
COJEOIIM_01430 4.3e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COJEOIIM_01431 1.1e-166 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COJEOIIM_01432 1.5e-120 potB P ABC transporter permease
COJEOIIM_01433 4.5e-104 potC U Binding-protein-dependent transport system inner membrane component
COJEOIIM_01434 1.3e-159 potD P ABC transporter
COJEOIIM_01435 2.3e-26
COJEOIIM_01436 0.0 L MobA MobL family protein
COJEOIIM_01437 6.1e-26
COJEOIIM_01438 2e-40
COJEOIIM_01439 4.3e-113 S protein conserved in bacteria
COJEOIIM_01440 1.2e-25
COJEOIIM_01441 9.9e-40 relB L Addiction module antitoxin, RelB DinJ family
COJEOIIM_01442 3.5e-132 S Fic/DOC family
COJEOIIM_01443 4.5e-168 repA S Replication initiator protein A
COJEOIIM_01444 8.5e-35
COJEOIIM_01445 2.4e-147 D CobQ CobB MinD ParA nucleotide binding domain protein
COJEOIIM_01446 7.6e-55 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
COJEOIIM_01447 6.2e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
COJEOIIM_01448 3.4e-10
COJEOIIM_01450 6.6e-76 S DNA primase
COJEOIIM_01451 7.4e-45 L Bifunctional DNA primase/polymerase, N-terminal
COJEOIIM_01459 1.1e-07 K Helix-turn-helix XRE-family like proteins
COJEOIIM_01460 2.8e-33 K Helix-turn-helix XRE-family like proteins
COJEOIIM_01461 9.9e-09 E Pfam:DUF955
COJEOIIM_01462 1.9e-121 sip L Belongs to the 'phage' integrase family
COJEOIIM_01463 9.1e-67 1.5.1.38 S NADPH-dependent FMN reductase
COJEOIIM_01464 5.8e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
COJEOIIM_01465 3.9e-76 L haloacid dehalogenase-like hydrolase
COJEOIIM_01466 4e-61 EG EamA-like transporter family
COJEOIIM_01467 5.3e-118 K AI-2E family transporter
COJEOIIM_01468 1.3e-173 malY 4.4.1.8 E Aminotransferase, class I
COJEOIIM_01469 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COJEOIIM_01471 5.3e-35 S virion core protein, lumpy skin disease virus
COJEOIIM_01472 1.1e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
COJEOIIM_01473 1.5e-269 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COJEOIIM_01474 1.2e-100 pncA Q Isochorismatase family
COJEOIIM_01475 2.5e-104 L Helix-turn-helix domain
COJEOIIM_01476 4.3e-109 L hmm pf00665
COJEOIIM_01477 1.5e-23 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COJEOIIM_01478 1.3e-89 saeS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
COJEOIIM_01479 5.1e-77 K response regulator
COJEOIIM_01481 2.6e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
COJEOIIM_01482 1.9e-92
COJEOIIM_01483 4.2e-48 L Transposase
COJEOIIM_01484 4.6e-79
COJEOIIM_01485 4.3e-258 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
COJEOIIM_01486 9.1e-76 3.1.21.3 V Type I restriction modification DNA specificity domain
COJEOIIM_01487 1.6e-131 L Belongs to the 'phage' integrase family
COJEOIIM_01488 7e-68 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
COJEOIIM_01489 1.9e-48 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
COJEOIIM_01490 1.5e-46
COJEOIIM_01491 3.3e-64
COJEOIIM_01492 4e-31 tnp L MULE transposase domain
COJEOIIM_01494 8.5e-64 V HNH endonuclease
COJEOIIM_01495 6.7e-114 L Transposase IS66 family
COJEOIIM_01496 5e-27 XK27_01125 L PFAM IS66 Orf2 family protein
COJEOIIM_01497 2.9e-93 yihY S Belongs to the UPF0761 family
COJEOIIM_01498 2.8e-12 mltD CBM50 M Lysin motif
COJEOIIM_01499 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COJEOIIM_01500 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
COJEOIIM_01501 5.1e-54 fld C Flavodoxin
COJEOIIM_01502 8.7e-53 gtcA S Teichoic acid glycosylation protein
COJEOIIM_01503 0.0 S Bacterial membrane protein YfhO
COJEOIIM_01504 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
COJEOIIM_01505 9.9e-123 S Sulfite exporter TauE/SafE
COJEOIIM_01506 1.1e-70 K Sugar-specific transcriptional regulator TrmB
COJEOIIM_01507 9.3e-169 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COJEOIIM_01508 3.5e-182 pepS E Thermophilic metalloprotease (M29)
COJEOIIM_01509 3e-266 E Amino acid permease
COJEOIIM_01510 4.9e-85 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
COJEOIIM_01511 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
COJEOIIM_01512 2.9e-78 galM 5.1.3.3 G Aldose 1-epimerase
COJEOIIM_01513 4.3e-213 malT G Transporter, major facilitator family protein
COJEOIIM_01514 4.2e-101 malR K Transcriptional regulator, LacI family
COJEOIIM_01515 2.3e-279 kup P Transport of potassium into the cell
COJEOIIM_01517 2e-20 S Domain of unknown function (DUF3284)
COJEOIIM_01518 5.2e-160 yfmL L DEAD DEAH box helicase
COJEOIIM_01519 7e-128 mocA S Oxidoreductase
COJEOIIM_01520 2e-24 S Domain of unknown function (DUF4828)
COJEOIIM_01521 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
COJEOIIM_01522 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
COJEOIIM_01523 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
COJEOIIM_01524 4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
COJEOIIM_01525 4.2e-161 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
COJEOIIM_01526 2.8e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
COJEOIIM_01527 3.6e-220 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
COJEOIIM_01528 4.9e-42 O ADP-ribosylglycohydrolase
COJEOIIM_01529 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
COJEOIIM_01530 6.4e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
COJEOIIM_01531 9.7e-35 K GNAT family
COJEOIIM_01532 1.7e-40
COJEOIIM_01534 1.6e-159 mgtE P Acts as a magnesium transporter
COJEOIIM_01535 1.3e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
COJEOIIM_01536 1.3e-116 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COJEOIIM_01537 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
COJEOIIM_01538 9e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
COJEOIIM_01539 1.7e-35 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
COJEOIIM_01540 6.3e-193 pbuX F xanthine permease
COJEOIIM_01541 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COJEOIIM_01542 1.6e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
COJEOIIM_01543 5.5e-64 S ECF transporter, substrate-specific component
COJEOIIM_01544 1.7e-126 mleP S Sodium Bile acid symporter family
COJEOIIM_01545 1.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
COJEOIIM_01546 1.8e-71 mleR K LysR family
COJEOIIM_01547 1.1e-56 K transcriptional
COJEOIIM_01548 5.9e-41 K Bacterial regulatory proteins, tetR family
COJEOIIM_01549 6.1e-60 T Belongs to the universal stress protein A family
COJEOIIM_01550 8.1e-44 K Copper transport repressor CopY TcrY
COJEOIIM_01551 2.1e-116 3.2.1.18 GH33 M Rib/alpha-like repeat
COJEOIIM_01552 1.4e-113 3.2.1.18 GH33 M Rib/alpha-like repeat
COJEOIIM_01554 1.9e-95 ypuA S Protein of unknown function (DUF1002)
COJEOIIM_01555 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
COJEOIIM_01556 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COJEOIIM_01557 4.6e-36 yncA 2.3.1.79 S Maltose acetyltransferase
COJEOIIM_01558 5.3e-206 yflS P Sodium:sulfate symporter transmembrane region
COJEOIIM_01559 7.2e-200 frdC 1.3.5.4 C FAD binding domain
COJEOIIM_01560 3.9e-238 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COJEOIIM_01561 2e-14 ybaN S Protein of unknown function (DUF454)
COJEOIIM_01562 1.4e-176 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
COJEOIIM_01563 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COJEOIIM_01564 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COJEOIIM_01565 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
COJEOIIM_01566 5.1e-72 ywlG S Belongs to the UPF0340 family
COJEOIIM_01567 5.2e-65 S Acetyltransferase (GNAT) domain
COJEOIIM_01569 3.5e-50 K Cro/C1-type HTH DNA-binding domain
COJEOIIM_01570 1.6e-174 spoVK O ATPase family associated with various cellular activities (AAA)
COJEOIIM_01573 8.3e-126 S Bacteriophage abortive infection AbiH
COJEOIIM_01574 4.5e-86 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain protein
COJEOIIM_01575 3.2e-37 hsdM 2.1.1.72 V type I restriction-modification system
COJEOIIM_01576 1.3e-162 hsdM 2.1.1.72 V cog cog0286
COJEOIIM_01577 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
COJEOIIM_01578 5.4e-19 K Cro/C1-type HTH DNA-binding domain
COJEOIIM_01579 9.1e-78 L AAA domain
COJEOIIM_01580 4.1e-16
COJEOIIM_01581 3e-22
COJEOIIM_01582 1.3e-75 K phage regulatory protein, rha family
COJEOIIM_01583 1.3e-17
COJEOIIM_01584 1.4e-121 L Mrr N-terminal domain
COJEOIIM_01585 9.9e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COJEOIIM_01586 9.8e-146 yegS 2.7.1.107 G Lipid kinase
COJEOIIM_01587 2.8e-255 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COJEOIIM_01588 4e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COJEOIIM_01589 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COJEOIIM_01590 9.3e-161 camS S sex pheromone
COJEOIIM_01591 1.3e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COJEOIIM_01592 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
COJEOIIM_01593 4.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
COJEOIIM_01597 1.8e-211 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COJEOIIM_01606 2.1e-07
COJEOIIM_01608 5.1e-08
COJEOIIM_01622 1.3e-147 XK27_08315 M Sulfatase
COJEOIIM_01623 3.2e-129 S Bacterial membrane protein YfhO
COJEOIIM_01624 8.8e-102 S Bacterial membrane protein, YfhO
COJEOIIM_01625 2.5e-72 S Bacterial membrane protein, YfhO
COJEOIIM_01626 3.6e-14
COJEOIIM_01627 1.5e-55 S Psort location CytoplasmicMembrane, score
COJEOIIM_01628 3.3e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
COJEOIIM_01629 1.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
COJEOIIM_01630 2.7e-156 XK27_09615 S reductase
COJEOIIM_01631 5.4e-67 XK27_09620 S NADPH-dependent FMN reductase
COJEOIIM_01632 4.7e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COJEOIIM_01633 1.2e-160 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
COJEOIIM_01634 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
COJEOIIM_01635 2.1e-30 gtcA S Teichoic acid glycosylation protein
COJEOIIM_01636 5e-115 rfbJ M Glycosyl transferase family 2
COJEOIIM_01637 8.5e-34 S Predicted membrane protein (DUF2142)
COJEOIIM_01638 3.3e-82
COJEOIIM_01639 7.6e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
COJEOIIM_01640 1e-133 coaA 2.7.1.33 F Pantothenic acid kinase
COJEOIIM_01641 6.3e-44 E GDSL-like Lipase/Acylhydrolase
COJEOIIM_01642 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COJEOIIM_01643 1.9e-190 glnPH2 P ABC transporter permease
COJEOIIM_01644 2.5e-214 yjeM E Amino Acid
COJEOIIM_01645 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
COJEOIIM_01646 8.1e-136 tetA EGP Major facilitator Superfamily
COJEOIIM_01648 2e-69 rny D Peptidase family M23
COJEOIIM_01649 9.8e-74 M transferase activity, transferring glycosyl groups
COJEOIIM_01650 5.8e-57 cps3F
COJEOIIM_01651 2e-160 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
COJEOIIM_01652 3.7e-65 S Glycosyltransferase like family 2
COJEOIIM_01653 1.6e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
COJEOIIM_01654 1.8e-95 M Core-2/I-Branching enzyme
COJEOIIM_01655 2e-91 rfbP M Bacterial sugar transferase
COJEOIIM_01656 1.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COJEOIIM_01657 1.6e-111 ywqE 3.1.3.48 GM PHP domain protein
COJEOIIM_01658 9.3e-82 ywqD 2.7.10.1 D Capsular exopolysaccharide family
COJEOIIM_01659 2.6e-77 epsB M biosynthesis protein
COJEOIIM_01660 3.2e-214 ugd 1.1.1.22 M UDP binding domain
COJEOIIM_01661 1e-42
COJEOIIM_01662 3e-41 S Acyltransferase family
COJEOIIM_01663 8e-130 S Membrane protein involved in the export of O-antigen and teichoic acid
COJEOIIM_01664 5.8e-26 S Acetyltransferase (Isoleucine patch superfamily)
COJEOIIM_01665 1.3e-42 M Glycosyltransferase like family 2
COJEOIIM_01667 7.3e-46 S Glycosyl transferase family 2
COJEOIIM_01668 4.7e-143 M Glycosyl transferase family 2
COJEOIIM_01669 6.8e-47 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
COJEOIIM_01670 1.9e-120 G Glycosyltransferase Family 4
COJEOIIM_01671 9.7e-174 rgpAc GT4 M Domain of unknown function (DUF1972)
COJEOIIM_01673 2e-80 S response to antibiotic
COJEOIIM_01674 9.8e-27 S zinc-ribbon domain
COJEOIIM_01675 9.4e-118 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
COJEOIIM_01676 9.9e-128 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COJEOIIM_01677 6.2e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COJEOIIM_01678 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
COJEOIIM_01679 1.2e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COJEOIIM_01680 1.3e-75 S Glycosyltransferase like family 2
COJEOIIM_01681 2.5e-61 S Glycosyltransferase like family 2
COJEOIIM_01682 2.6e-117 cps1D M Domain of unknown function (DUF4422)
COJEOIIM_01683 3e-39 S CAAX protease self-immunity
COJEOIIM_01684 9.1e-89 yvyE 3.4.13.9 S YigZ family
COJEOIIM_01685 2.3e-58 S Haloacid dehalogenase-like hydrolase
COJEOIIM_01686 2.9e-153 EGP Major facilitator Superfamily
COJEOIIM_01688 5.3e-68 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
COJEOIIM_01689 1.2e-27 yraB K transcriptional regulator
COJEOIIM_01690 9.8e-90 S NADPH-dependent FMN reductase
COJEOIIM_01691 1e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COJEOIIM_01692 1.5e-55 S ECF transporter, substrate-specific component
COJEOIIM_01693 2.5e-96 znuB U ABC 3 transport family
COJEOIIM_01694 1e-98 fhuC P ABC transporter
COJEOIIM_01695 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
COJEOIIM_01696 7.6e-38
COJEOIIM_01697 6.5e-54 XK27_01040 S Protein of unknown function (DUF1129)
COJEOIIM_01698 5.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COJEOIIM_01699 3.4e-23 yyzM S Bacterial protein of unknown function (DUF951)
COJEOIIM_01700 1.8e-108 spo0J K Belongs to the ParB family
COJEOIIM_01701 6.5e-118 soj D Sporulation initiation inhibitor
COJEOIIM_01702 1.4e-81 noc K Belongs to the ParB family
COJEOIIM_01703 4e-101 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
COJEOIIM_01704 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
COJEOIIM_01705 2.4e-109 3.1.4.46 C phosphodiesterase
COJEOIIM_01706 0.0 pacL 3.6.3.8 P P-type ATPase
COJEOIIM_01707 1.8e-223 yeeA V Type II restriction enzyme, methylase subunits
COJEOIIM_01708 2.4e-257 yeeB L DEAD-like helicases superfamily
COJEOIIM_01709 7.4e-92 pstS P T5orf172
COJEOIIM_01710 6.9e-15
COJEOIIM_01711 4.6e-24
COJEOIIM_01714 1.3e-161 potE2 E amino acid
COJEOIIM_01715 5.4e-87 ald 1.4.1.1 C Belongs to the AlaDH PNT family
COJEOIIM_01716 2.7e-48 ald 1.4.1.1 C Belongs to the AlaDH PNT family
COJEOIIM_01717 2.7e-116 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
COJEOIIM_01718 1.9e-57 racA K Domain of unknown function (DUF1836)
COJEOIIM_01719 3.5e-80 yitS S EDD domain protein, DegV family
COJEOIIM_01720 1.1e-45 yjaB_1 K Acetyltransferase (GNAT) domain
COJEOIIM_01721 4.4e-07
COJEOIIM_01722 2.4e-286 hsdR 3.1.21.3 L DEAD/DEAH box helicase
COJEOIIM_01723 4e-225 hsdM 2.1.1.72 V type I restriction-modification system
COJEOIIM_01724 8.6e-90 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
COJEOIIM_01725 4.1e-67
COJEOIIM_01726 7.3e-118 O AAA domain (Cdc48 subfamily)
COJEOIIM_01727 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COJEOIIM_01728 0.0 O Belongs to the peptidase S8 family
COJEOIIM_01729 4.7e-26 S protein encoded in hypervariable junctions of pilus gene clusters
COJEOIIM_01730 9e-102 qmcA O prohibitin homologues
COJEOIIM_01732 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
COJEOIIM_01733 1.2e-57 tlpA2 L Transposase IS200 like
COJEOIIM_01734 2e-159 L transposase, IS605 OrfB family
COJEOIIM_01735 1.2e-84 dps P Ferritin-like domain
COJEOIIM_01736 1.1e-98 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
COJEOIIM_01737 5.8e-44 L hmm pf00665
COJEOIIM_01738 3.4e-19 tnp
COJEOIIM_01739 7.1e-17 tnp L Transposase IS66 family
COJEOIIM_01740 1.7e-32 P Heavy-metal-associated domain
COJEOIIM_01741 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
COJEOIIM_01742 1.8e-20 L PFAM transposase IS3 IS911 family protein
COJEOIIM_01743 2.7e-81 L Integrase core domain
COJEOIIM_01744 2.6e-129 EGP Major Facilitator Superfamily
COJEOIIM_01745 1.4e-98 EGP Major Facilitator Superfamily
COJEOIIM_01746 1.3e-72 K Transcriptional regulator, LysR family
COJEOIIM_01747 1.6e-138 G Xylose isomerase-like TIM barrel
COJEOIIM_01748 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
COJEOIIM_01749 1.6e-217 1.3.5.4 C FAD binding domain
COJEOIIM_01750 6.5e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
COJEOIIM_01751 3.8e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
COJEOIIM_01752 1.4e-142 xerS L Phage integrase family
COJEOIIM_01756 1.6e-90 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
COJEOIIM_01757 1.4e-70 ptp3 3.1.3.48 T Tyrosine phosphatase family
COJEOIIM_01758 2.4e-75 desR K helix_turn_helix, Lux Regulon
COJEOIIM_01759 5.4e-57 salK 2.7.13.3 T Histidine kinase
COJEOIIM_01760 1.9e-53 yvfS V ABC-2 type transporter
COJEOIIM_01761 1.5e-78 yvfR V ABC transporter
COJEOIIM_01763 3.4e-10 S Protein of unknown function (DUF805)
COJEOIIM_01764 1.8e-08 K transcriptional
COJEOIIM_01765 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
COJEOIIM_01766 2.3e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
COJEOIIM_01767 1.5e-29
COJEOIIM_01768 8.7e-63 sip L Belongs to the 'phage' integrase family
COJEOIIM_01769 6.5e-07
COJEOIIM_01772 1.7e-30 M CHAP domain
COJEOIIM_01774 2.6e-192 U type IV secretory pathway VirB4
COJEOIIM_01775 8.7e-26
COJEOIIM_01777 3.4e-77
COJEOIIM_01778 8.4e-219 U TraM recognition site of TraD and TraG
COJEOIIM_01782 2.2e-148 clpB O Belongs to the ClpA ClpB family
COJEOIIM_01785 7.1e-165 topA2 5.99.1.2 G Topoisomerase IA
COJEOIIM_01786 2.1e-43 L Protein of unknown function (DUF3991)
COJEOIIM_01787 1e-68
COJEOIIM_01789 1.4e-40 V Type I restriction modification DNA specificity domain
COJEOIIM_01790 3.2e-212 V N-6 DNA Methylase
COJEOIIM_01791 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COJEOIIM_01792 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
COJEOIIM_01793 1.7e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COJEOIIM_01794 5.4e-128 cpoA GT4 M Glycosyltransferase, group 1 family protein
COJEOIIM_01795 8.8e-162 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
COJEOIIM_01796 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COJEOIIM_01797 9.7e-37 ptsH G phosphocarrier protein HPR
COJEOIIM_01798 1.5e-15
COJEOIIM_01799 0.0 clpE O Belongs to the ClpA ClpB family
COJEOIIM_01800 6.6e-23 XK27_09445 S Domain of unknown function (DUF1827)
COJEOIIM_01801 2.9e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
COJEOIIM_01802 0.0 rafA 3.2.1.22 G alpha-galactosidase
COJEOIIM_01803 1.6e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
COJEOIIM_01804 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COJEOIIM_01805 2.6e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
COJEOIIM_01806 5.9e-111 galR K Transcriptional regulator
COJEOIIM_01807 4e-289 lacS G Transporter
COJEOIIM_01808 0.0 lacL 3.2.1.23 G -beta-galactosidase
COJEOIIM_01809 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COJEOIIM_01810 1.4e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
COJEOIIM_01811 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
COJEOIIM_01812 3.4e-91 yueF S AI-2E family transporter
COJEOIIM_01813 2.6e-97 ygaC J Belongs to the UPF0374 family
COJEOIIM_01814 9.4e-192 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COJEOIIM_01815 2.9e-68 recX 2.4.1.337 GT4 S Regulatory protein RecX
COJEOIIM_01816 1.1e-19 yvrI K RNA polymerase sigma factor, sigma-70 family
COJEOIIM_01817 7e-23 S Cytochrome B5
COJEOIIM_01818 2.3e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
COJEOIIM_01819 7.6e-60
COJEOIIM_01820 1.3e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
COJEOIIM_01821 6.6e-156 nrnB S DHHA1 domain
COJEOIIM_01822 1.5e-91 yunF F Protein of unknown function DUF72
COJEOIIM_01823 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
COJEOIIM_01824 5.4e-13
COJEOIIM_01825 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COJEOIIM_01826 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COJEOIIM_01827 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
COJEOIIM_01828 4.1e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COJEOIIM_01829 4.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
COJEOIIM_01830 7.7e-61 M ErfK YbiS YcfS YnhG
COJEOIIM_01832 2.8e-83 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COJEOIIM_01833 1.2e-180 pbuG S permease
COJEOIIM_01835 1.8e-78 S Cell surface protein
COJEOIIM_01837 6.4e-257 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
COJEOIIM_01838 6.3e-61
COJEOIIM_01839 3.6e-41 rpmE2 J Ribosomal protein L31
COJEOIIM_01840 5.3e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
COJEOIIM_01841 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COJEOIIM_01843 1.6e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COJEOIIM_01844 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
COJEOIIM_01845 1.8e-32 ywiB S Domain of unknown function (DUF1934)
COJEOIIM_01846 2e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
COJEOIIM_01847 3.3e-205 ywfO S HD domain protein
COJEOIIM_01848 7.5e-88 S hydrolase
COJEOIIM_01849 2e-105 ydcZ S Putative inner membrane exporter, YdcZ
COJEOIIM_01850 1.3e-63
COJEOIIM_01852 1.1e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
COJEOIIM_01853 2.3e-22
COJEOIIM_01854 3e-56 spoVK O ATPase family associated with various cellular activities (AAA)
COJEOIIM_01856 2.2e-86 S overlaps another CDS with the same product name
COJEOIIM_01857 1.6e-125 S overlaps another CDS with the same product name
COJEOIIM_01858 1.9e-98 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COJEOIIM_01859 1.1e-62 bCE_4747 S Beta-lactamase superfamily domain
COJEOIIM_01860 2e-289 ybiT S ABC transporter, ATP-binding protein
COJEOIIM_01861 1e-78 2.4.2.3 F Phosphorylase superfamily
COJEOIIM_01862 1.1e-23
COJEOIIM_01863 7.6e-112 dkg S reductase
COJEOIIM_01864 7.7e-19 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
COJEOIIM_01865 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COJEOIIM_01866 1.1e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COJEOIIM_01867 2.1e-46 EGP Transmembrane secretion effector
COJEOIIM_01868 5.2e-137 purR 2.4.2.7 F pur operon repressor
COJEOIIM_01869 6.6e-53 adhR K helix_turn_helix, mercury resistance
COJEOIIM_01870 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COJEOIIM_01871 1.9e-104 pfoS S Phosphotransferase system, EIIC
COJEOIIM_01872 2.9e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COJEOIIM_01873 6.2e-152 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
COJEOIIM_01874 1.9e-196 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
COJEOIIM_01875 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
COJEOIIM_01876 8.6e-115 glcR K DeoR C terminal sensor domain
COJEOIIM_01877 4.5e-171 patA 2.6.1.1 E Aminotransferase
COJEOIIM_01878 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
COJEOIIM_01880 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
COJEOIIM_01881 1.4e-172 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
COJEOIIM_01882 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
COJEOIIM_01883 6.2e-21 S Family of unknown function (DUF5322)
COJEOIIM_01884 5e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
COJEOIIM_01885 1.8e-38
COJEOIIM_01888 2.5e-149 EGP Sugar (and other) transporter
COJEOIIM_01889 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
COJEOIIM_01890 4.8e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COJEOIIM_01891 9.4e-183 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
COJEOIIM_01892 4.2e-73 alkD L DNA alkylation repair enzyme
COJEOIIM_01893 3.8e-136 EG EamA-like transporter family
COJEOIIM_01894 3.6e-150 S Tetratricopeptide repeat protein
COJEOIIM_01895 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
COJEOIIM_01896 4.3e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
COJEOIIM_01897 7e-127 corA P CorA-like Mg2+ transporter protein
COJEOIIM_01898 8.5e-161 nhaC C Na H antiporter NhaC
COJEOIIM_01899 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COJEOIIM_01900 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
COJEOIIM_01902 7.2e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COJEOIIM_01903 2.9e-154 iscS 2.8.1.7 E Aminotransferase class V
COJEOIIM_01904 3.7e-41 XK27_04120 S Putative amino acid metabolism
COJEOIIM_01905 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COJEOIIM_01906 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COJEOIIM_01907 4.3e-15 S Protein of unknown function (DUF2929)
COJEOIIM_01908 0.0 dnaE 2.7.7.7 L DNA polymerase
COJEOIIM_01909 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
COJEOIIM_01910 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
COJEOIIM_01912 1e-39 ypaA S Protein of unknown function (DUF1304)
COJEOIIM_01913 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COJEOIIM_01914 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COJEOIIM_01915 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COJEOIIM_01916 1.2e-196 FbpA K Fibronectin-binding protein
COJEOIIM_01917 3.1e-40 K Transcriptional regulator
COJEOIIM_01918 2.2e-117 degV S EDD domain protein, DegV family
COJEOIIM_01919 7.8e-71 lepB 3.4.21.89 U Signal peptidase, peptidase S26
COJEOIIM_01920 2.4e-40 6.3.3.2 S ASCH
COJEOIIM_01921 1.3e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COJEOIIM_01922 1.7e-79 yjjH S Calcineurin-like phosphoesterase
COJEOIIM_01923 3.1e-95 EG EamA-like transporter family
COJEOIIM_01924 2.3e-85 natB CP ABC-type Na efflux pump, permease component
COJEOIIM_01925 6.2e-112 natA S Domain of unknown function (DUF4162)
COJEOIIM_01926 4.8e-23 K Acetyltransferase (GNAT) domain
COJEOIIM_01928 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COJEOIIM_01929 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
COJEOIIM_01930 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
COJEOIIM_01931 9.1e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
COJEOIIM_01932 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
COJEOIIM_01933 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COJEOIIM_01934 1.4e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
COJEOIIM_01935 4.5e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COJEOIIM_01936 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
COJEOIIM_01937 4.5e-90 recO L Involved in DNA repair and RecF pathway recombination
COJEOIIM_01938 1e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COJEOIIM_01939 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
COJEOIIM_01940 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COJEOIIM_01941 3.5e-153 phoH T phosphate starvation-inducible protein PhoH
COJEOIIM_01942 7.5e-83 lytH 3.5.1.28 M Ami_3
COJEOIIM_01943 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
COJEOIIM_01944 5.9e-12 M Lysin motif
COJEOIIM_01945 2e-128 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
COJEOIIM_01946 7.1e-59 ypbB 5.1.3.1 S Helix-turn-helix domain
COJEOIIM_01947 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
COJEOIIM_01948 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
COJEOIIM_01949 7.1e-120 ica2 GT2 M Glycosyl transferase family group 2
COJEOIIM_01950 4.1e-43
COJEOIIM_01951 2.1e-91 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COJEOIIM_01953 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COJEOIIM_01954 1.3e-212 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COJEOIIM_01955 8.1e-280 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
COJEOIIM_01956 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
COJEOIIM_01957 3.3e-117 EGP Major Facilitator Superfamily
COJEOIIM_01958 1.1e-124 akr5f 1.1.1.346 S reductase
COJEOIIM_01959 2.7e-72 K Transcriptional regulator
COJEOIIM_01960 9.9e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
COJEOIIM_01961 9.7e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COJEOIIM_01962 2.9e-143 E methionine synthase, vitamin-B12 independent
COJEOIIM_01963 3.7e-106 metQ1 P Belongs to the nlpA lipoprotein family
COJEOIIM_01964 1.5e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COJEOIIM_01965 2.7e-70 metI P ABC transporter permease
COJEOIIM_01966 3.3e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COJEOIIM_01967 3e-84 drgA C nitroreductase
COJEOIIM_01968 2.5e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
COJEOIIM_01969 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
COJEOIIM_01970 8.1e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
COJEOIIM_01971 1.4e-263 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
COJEOIIM_01973 2.3e-150 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COJEOIIM_01974 2.4e-31 metI U ABC transporter permease
COJEOIIM_01975 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
COJEOIIM_01976 1.8e-53 S Protein of unknown function (DUF4256)
COJEOIIM_01979 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
COJEOIIM_01980 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
COJEOIIM_01981 2.6e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
COJEOIIM_01982 4e-230 lpdA 1.8.1.4 C Dehydrogenase
COJEOIIM_01983 2.1e-148 lplA 6.3.1.20 H Lipoate-protein ligase
COJEOIIM_01984 9.2e-56 S Protein of unknown function (DUF975)
COJEOIIM_01985 5.7e-78 E GDSL-like Lipase/Acylhydrolase family
COJEOIIM_01986 1.4e-38
COJEOIIM_01987 4.1e-27 gcvR T Belongs to the UPF0237 family
COJEOIIM_01988 2.1e-220 XK27_08635 S UPF0210 protein
COJEOIIM_01989 4.5e-87 fruR K DeoR C terminal sensor domain
COJEOIIM_01990 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
COJEOIIM_01991 4.8e-282 fruA 2.7.1.202 GT Phosphotransferase System
COJEOIIM_01992 5.5e-144 dapE 3.5.1.18 E Peptidase dimerisation domain
COJEOIIM_01993 1e-149 E glutamate:sodium symporter activity
COJEOIIM_01994 1.2e-145 Q Imidazolonepropionase and related amidohydrolases
COJEOIIM_01995 9.1e-50 cps3F
COJEOIIM_01996 3e-82 S Membrane
COJEOIIM_01997 1.8e-254 E Amino acid permease
COJEOIIM_01998 2.9e-225 cadA P P-type ATPase
COJEOIIM_01999 6.4e-114 degV S EDD domain protein, DegV family
COJEOIIM_02000 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
COJEOIIM_02001 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
COJEOIIM_02002 7.2e-27 ydiI Q Thioesterase superfamily
COJEOIIM_02003 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
COJEOIIM_02004 3.5e-141 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
COJEOIIM_02005 5.6e-82 S L,D-transpeptidase catalytic domain
COJEOIIM_02006 8.8e-166 EGP Major facilitator Superfamily
COJEOIIM_02007 2.3e-21 K helix_turn_helix multiple antibiotic resistance protein
COJEOIIM_02008 6.6e-225 pipD E Dipeptidase
COJEOIIM_02009 4.1e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COJEOIIM_02010 2.6e-32 ywjH S Protein of unknown function (DUF1634)
COJEOIIM_02011 6.5e-119 yxaA S membrane transporter protein
COJEOIIM_02012 1.7e-82 lysR5 K LysR substrate binding domain
COJEOIIM_02013 7.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
COJEOIIM_02014 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
COJEOIIM_02015 7.3e-271 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
COJEOIIM_02016 2.3e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
COJEOIIM_02017 1.9e-243 lysP E amino acid
COJEOIIM_02018 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)