ORF_ID e_value Gene_name EC_number CAZy COGs Description
LIEFNNIO_00002 1.6e-197 dtpT U amino acid peptide transporter
LIEFNNIO_00003 1.1e-07
LIEFNNIO_00005 1e-89 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LIEFNNIO_00006 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
LIEFNNIO_00007 1.4e-90 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LIEFNNIO_00008 9.5e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LIEFNNIO_00009 1.8e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LIEFNNIO_00010 2.2e-251 yhgF K Tex-like protein N-terminal domain protein
LIEFNNIO_00011 3e-43 ydcK S Belongs to the SprT family
LIEFNNIO_00013 3.5e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIEFNNIO_00014 1.1e-127 mleP2 S Sodium Bile acid symporter family
LIEFNNIO_00015 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LIEFNNIO_00016 1e-33 S Enterocin A Immunity
LIEFNNIO_00017 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
LIEFNNIO_00018 8.1e-18 HA62_12640 S GCN5-related N-acetyl-transferase
LIEFNNIO_00019 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
LIEFNNIO_00020 3.5e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LIEFNNIO_00021 8.2e-154 yacL S domain protein
LIEFNNIO_00022 1.4e-246 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LIEFNNIO_00023 2.8e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LIEFNNIO_00024 3.8e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LIEFNNIO_00025 1.2e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LIEFNNIO_00026 7e-71 yacP S YacP-like NYN domain
LIEFNNIO_00027 3.1e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LIEFNNIO_00028 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LIEFNNIO_00029 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
LIEFNNIO_00030 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LIEFNNIO_00031 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LIEFNNIO_00032 1.7e-74 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LIEFNNIO_00033 7.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LIEFNNIO_00034 1.6e-55
LIEFNNIO_00035 2.7e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LIEFNNIO_00036 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LIEFNNIO_00037 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LIEFNNIO_00038 4.8e-45 nrdI F NrdI Flavodoxin like
LIEFNNIO_00039 1.2e-27 nrdH O Glutaredoxin
LIEFNNIO_00040 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
LIEFNNIO_00041 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LIEFNNIO_00042 4.6e-212 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LIEFNNIO_00043 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LIEFNNIO_00044 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LIEFNNIO_00045 7.1e-29 yaaL S Protein of unknown function (DUF2508)
LIEFNNIO_00046 8.1e-66 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LIEFNNIO_00047 3e-83 holB 2.7.7.7 L DNA polymerase III
LIEFNNIO_00048 1.4e-40 yabA L Involved in initiation control of chromosome replication
LIEFNNIO_00049 3.3e-105 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LIEFNNIO_00050 7.2e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
LIEFNNIO_00051 1.2e-140 ansA 3.5.1.1 EJ Asparaginase
LIEFNNIO_00052 8.2e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
LIEFNNIO_00053 1.1e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
LIEFNNIO_00054 9.2e-160 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LIEFNNIO_00055 2.6e-256 uup S ABC transporter, ATP-binding protein
LIEFNNIO_00056 9.7e-99 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LIEFNNIO_00057 1.3e-31 S CAAX protease self-immunity
LIEFNNIO_00058 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LIEFNNIO_00059 1.1e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LIEFNNIO_00060 5.7e-269 aha1 P COG COG0474 Cation transport ATPase
LIEFNNIO_00061 4.9e-297 ydaO E amino acid
LIEFNNIO_00062 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
LIEFNNIO_00063 1.9e-128 comFA L Helicase C-terminal domain protein
LIEFNNIO_00064 3e-50 comFC S Competence protein
LIEFNNIO_00065 2.1e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LIEFNNIO_00066 9.1e-95 yeaN P Major Facilitator Superfamily
LIEFNNIO_00067 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LIEFNNIO_00068 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LIEFNNIO_00069 9.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
LIEFNNIO_00070 1.3e-85 K response regulator
LIEFNNIO_00071 5.3e-86 phoR 2.7.13.3 T Histidine kinase
LIEFNNIO_00072 4.1e-08 KT PspC domain protein
LIEFNNIO_00073 3.5e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
LIEFNNIO_00074 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LIEFNNIO_00075 3.3e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LIEFNNIO_00076 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LIEFNNIO_00077 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LIEFNNIO_00078 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LIEFNNIO_00079 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LIEFNNIO_00080 1.3e-79 ylbE GM NAD dependent epimerase dehydratase family protein
LIEFNNIO_00081 7.5e-126 rapZ S Displays ATPase and GTPase activities
LIEFNNIO_00082 6.3e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LIEFNNIO_00083 1.8e-149 whiA K May be required for sporulation
LIEFNNIO_00084 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LIEFNNIO_00086 4.2e-136 cggR K Putative sugar-binding domain
LIEFNNIO_00087 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LIEFNNIO_00088 1.1e-207 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LIEFNNIO_00089 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LIEFNNIO_00090 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LIEFNNIO_00091 1.4e-131 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LIEFNNIO_00092 7.2e-103 K response regulator
LIEFNNIO_00093 1.8e-169 T PhoQ Sensor
LIEFNNIO_00094 1.1e-145 lmrP E Major Facilitator Superfamily
LIEFNNIO_00095 3.5e-179 clcA P chloride
LIEFNNIO_00096 2.8e-19 secG U Preprotein translocase
LIEFNNIO_00097 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LIEFNNIO_00098 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LIEFNNIO_00099 3.1e-42 yxjI
LIEFNNIO_00100 2.4e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
LIEFNNIO_00101 1.5e-105 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LIEFNNIO_00102 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LIEFNNIO_00103 4.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
LIEFNNIO_00104 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
LIEFNNIO_00105 6e-115 murB 1.3.1.98 M Cell wall formation
LIEFNNIO_00106 2.4e-71 S Protein of unknown function (DUF1361)
LIEFNNIO_00107 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LIEFNNIO_00108 5.3e-68 ybbR S YbbR-like protein
LIEFNNIO_00109 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LIEFNNIO_00110 5.8e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
LIEFNNIO_00111 4.9e-129 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
LIEFNNIO_00112 2.3e-19 cutC P Participates in the control of copper homeostasis
LIEFNNIO_00114 4.9e-94 S Bacterial membrane protein, YfhO
LIEFNNIO_00115 8.1e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LIEFNNIO_00116 1.7e-163 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LIEFNNIO_00117 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
LIEFNNIO_00118 5.8e-99 rrmA 2.1.1.187 H Methyltransferase
LIEFNNIO_00119 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LIEFNNIO_00120 6.8e-288 ftsK D Belongs to the FtsK SpoIIIE SftA family
LIEFNNIO_00121 2e-108 ymfF S Peptidase M16 inactive domain protein
LIEFNNIO_00122 9.3e-149 ymfH S Peptidase M16
LIEFNNIO_00123 4.9e-91 IQ Enoyl-(Acyl carrier protein) reductase
LIEFNNIO_00124 8.5e-64 ymfM S Helix-turn-helix domain
LIEFNNIO_00125 8e-84 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LIEFNNIO_00126 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LIEFNNIO_00127 5e-181 rny S Endoribonuclease that initiates mRNA decay
LIEFNNIO_00128 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LIEFNNIO_00129 4.9e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LIEFNNIO_00130 1.6e-71 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LIEFNNIO_00131 8.2e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LIEFNNIO_00132 7.9e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LIEFNNIO_00133 7.8e-208 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LIEFNNIO_00134 1.4e-12 yajC U Preprotein translocase
LIEFNNIO_00136 4.3e-61 uspA T universal stress protein
LIEFNNIO_00138 2e-208 yfnA E Amino Acid
LIEFNNIO_00139 2e-116 lutA C Cysteine-rich domain
LIEFNNIO_00140 4e-244 lutB C 4Fe-4S dicluster domain
LIEFNNIO_00141 1.6e-65 yrjD S LUD domain
LIEFNNIO_00142 2.6e-145 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LIEFNNIO_00143 7.5e-13
LIEFNNIO_00144 1.2e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
LIEFNNIO_00145 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LIEFNNIO_00146 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LIEFNNIO_00147 2.1e-36 yrzL S Belongs to the UPF0297 family
LIEFNNIO_00148 8.8e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LIEFNNIO_00149 1.9e-33 yrzB S Belongs to the UPF0473 family
LIEFNNIO_00150 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LIEFNNIO_00151 1.6e-17 cvpA S Colicin V production protein
LIEFNNIO_00152 7.2e-309 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LIEFNNIO_00153 9.9e-41 trxA O Belongs to the thioredoxin family
LIEFNNIO_00154 1.1e-60 yslB S Protein of unknown function (DUF2507)
LIEFNNIO_00155 5.5e-72 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LIEFNNIO_00156 4.4e-41 S Phosphoesterase
LIEFNNIO_00159 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LIEFNNIO_00160 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LIEFNNIO_00161 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LIEFNNIO_00162 1.3e-199 oatA I Acyltransferase
LIEFNNIO_00163 1.4e-16
LIEFNNIO_00165 9.8e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LIEFNNIO_00166 1.7e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
LIEFNNIO_00167 9.9e-218 recJ L Single-stranded-DNA-specific exonuclease RecJ
LIEFNNIO_00168 2.8e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LIEFNNIO_00169 8.4e-298 S membrane
LIEFNNIO_00170 1.2e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
LIEFNNIO_00172 1.8e-45 yviA S Protein of unknown function (DUF421)
LIEFNNIO_00175 5e-124 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LIEFNNIO_00176 5e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LIEFNNIO_00177 1.2e-52 tag 3.2.2.20 L glycosylase
LIEFNNIO_00178 3.2e-73 usp6 T universal stress protein
LIEFNNIO_00180 4.9e-187 rarA L recombination factor protein RarA
LIEFNNIO_00181 5.9e-24 yueI S Protein of unknown function (DUF1694)
LIEFNNIO_00182 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LIEFNNIO_00183 1.6e-55 ytsP 1.8.4.14 T GAF domain-containing protein
LIEFNNIO_00184 2.1e-172 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LIEFNNIO_00185 2.2e-162 iscS2 2.8.1.7 E Aminotransferase class V
LIEFNNIO_00186 4.2e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LIEFNNIO_00187 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LIEFNNIO_00188 1.4e-136 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LIEFNNIO_00189 6.2e-80 radC L DNA repair protein
LIEFNNIO_00190 4.5e-21 K Cold shock
LIEFNNIO_00191 3.6e-156 mreB D cell shape determining protein MreB
LIEFNNIO_00192 2.1e-88 mreC M Involved in formation and maintenance of cell shape
LIEFNNIO_00193 4.4e-54 mreD M rod shape-determining protein MreD
LIEFNNIO_00194 3.2e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LIEFNNIO_00195 3.1e-126 minD D Belongs to the ParA family
LIEFNNIO_00196 1.9e-94 glnP P ABC transporter permease
LIEFNNIO_00197 1.1e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LIEFNNIO_00198 1.4e-108 aatB ET ABC transporter substrate-binding protein
LIEFNNIO_00199 7.5e-100 D Alpha beta
LIEFNNIO_00201 2.7e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
LIEFNNIO_00202 4.5e-08 S Protein of unknown function (DUF3397)
LIEFNNIO_00203 5.2e-64 mraZ K Belongs to the MraZ family
LIEFNNIO_00204 3.6e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LIEFNNIO_00205 2.5e-11 ftsL D cell division protein FtsL
LIEFNNIO_00206 6.9e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
LIEFNNIO_00207 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LIEFNNIO_00208 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LIEFNNIO_00209 6.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LIEFNNIO_00210 5.7e-62 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LIEFNNIO_00211 4.4e-189 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LIEFNNIO_00212 2.9e-179 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LIEFNNIO_00213 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LIEFNNIO_00214 3e-19 yggT S YGGT family
LIEFNNIO_00215 7.7e-82 ylmH S S4 domain protein
LIEFNNIO_00216 5.1e-62 divIVA D DivIVA domain protein
LIEFNNIO_00217 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LIEFNNIO_00218 4.4e-91 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIEFNNIO_00219 3.3e-74 draG O ADP-ribosylglycohydrolase
LIEFNNIO_00221 1.9e-85 2.7.7.12 C Domain of unknown function (DUF4931)
LIEFNNIO_00222 4.8e-93 T Calcineurin-like phosphoesterase superfamily domain
LIEFNNIO_00223 2.1e-48 lytE M LysM domain protein
LIEFNNIO_00224 2.3e-19 glpE P Rhodanese Homology Domain
LIEFNNIO_00225 5.7e-29 xlyB 3.5.1.28 CBM50 M LysM domain
LIEFNNIO_00226 2.6e-159 asnA 6.3.1.1 F aspartate--ammonia ligase
LIEFNNIO_00227 3e-193 cydA 1.10.3.14 C ubiquinol oxidase
LIEFNNIO_00228 5.6e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
LIEFNNIO_00229 7.8e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LIEFNNIO_00230 3.6e-220 cydD CO ABC transporter transmembrane region
LIEFNNIO_00231 6.2e-97 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LIEFNNIO_00232 3.3e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
LIEFNNIO_00233 9.5e-156 ndh 1.6.99.3 C NADH dehydrogenase
LIEFNNIO_00234 1.5e-146 pbuO_1 S Permease family
LIEFNNIO_00235 8.1e-43 2.7.7.65 T GGDEF domain
LIEFNNIO_00236 9.6e-28 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
LIEFNNIO_00237 1.4e-81 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
LIEFNNIO_00238 9.3e-182
LIEFNNIO_00239 1e-205 S Protein conserved in bacteria
LIEFNNIO_00240 7.7e-201 ydaM M Glycosyl transferase family group 2
LIEFNNIO_00241 3.4e-310 ydaN S Bacterial cellulose synthase subunit
LIEFNNIO_00242 2.4e-113 2.7.7.65 T diguanylate cyclase activity
LIEFNNIO_00243 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
LIEFNNIO_00244 1.9e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
LIEFNNIO_00245 2.6e-308 L Helicase C-terminal domain protein
LIEFNNIO_00246 0.0 rafA 3.2.1.22 G alpha-galactosidase
LIEFNNIO_00247 8.9e-54 S Membrane
LIEFNNIO_00248 3.5e-64 K helix_turn_helix, arabinose operon control protein
LIEFNNIO_00249 1.1e-44
LIEFNNIO_00250 5e-204 pipD E Dipeptidase
LIEFNNIO_00251 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
LIEFNNIO_00252 2.4e-189 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LIEFNNIO_00253 3e-61 speG J Acetyltransferase (GNAT) domain
LIEFNNIO_00254 5.1e-113 yitU 3.1.3.104 S hydrolase
LIEFNNIO_00255 1.8e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
LIEFNNIO_00256 4.8e-81
LIEFNNIO_00257 3.8e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
LIEFNNIO_00258 6.7e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
LIEFNNIO_00259 1.8e-48 cps4C M Chain length determinant protein
LIEFNNIO_00260 9.4e-65 cpsD D AAA domain
LIEFNNIO_00261 7.9e-89 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
LIEFNNIO_00262 9.8e-127 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
LIEFNNIO_00263 1.7e-165 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
LIEFNNIO_00264 4.8e-77 epsL M Bacterial sugar transferase
LIEFNNIO_00265 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
LIEFNNIO_00266 1.9e-123 2.4.1.52 GT4 M Glycosyl transferases group 1
LIEFNNIO_00267 8.1e-80 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
LIEFNNIO_00269 9.3e-60 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
LIEFNNIO_00270 1.3e-74 M Glycosyltransferase Family 4
LIEFNNIO_00271 1.7e-42 GT2 V Glycosyl transferase, family 2
LIEFNNIO_00272 2.5e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
LIEFNNIO_00274 1.6e-52
LIEFNNIO_00275 2.3e-116 S Glycosyltransferase WbsX
LIEFNNIO_00276 4.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
LIEFNNIO_00277 6.9e-103 cps2I S Psort location CytoplasmicMembrane, score
LIEFNNIO_00278 6.1e-146 lspL 5.1.3.6 GM RmlD substrate binding domain
LIEFNNIO_00279 1.1e-178 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LIEFNNIO_00280 6.9e-65 M Glycosyl transferases group 1
LIEFNNIO_00281 5.6e-126 M Glycosyl transferases group 1
LIEFNNIO_00284 1.7e-82 qorB 1.6.5.2 GM NmrA-like family
LIEFNNIO_00285 3.6e-39 K Transcriptional regulator
LIEFNNIO_00287 5e-71 1.1.1.1 C Zinc-binding dehydrogenase
LIEFNNIO_00289 5.7e-41 S Protein of unknown function (DUF1211)
LIEFNNIO_00290 7.3e-27 ybl78 L Conserved phage C-terminus (Phg_2220_C)
LIEFNNIO_00292 2.4e-39 wecD M Acetyltransferase (GNAT) family
LIEFNNIO_00293 1.6e-65 H Methyltransferase domain
LIEFNNIO_00295 2.9e-16 K DNA-templated transcription, initiation
LIEFNNIO_00297 2.2e-08 S Protein of unknown function (DUF2922)
LIEFNNIO_00300 4.9e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
LIEFNNIO_00301 2.9e-27 ysxB J Cysteine protease Prp
LIEFNNIO_00302 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LIEFNNIO_00303 1e-12
LIEFNNIO_00306 3.1e-71
LIEFNNIO_00307 1.4e-101 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
LIEFNNIO_00308 2.5e-177 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
LIEFNNIO_00309 1e-122 xerC D Belongs to the 'phage' integrase family. XerC subfamily
LIEFNNIO_00310 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LIEFNNIO_00311 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LIEFNNIO_00312 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LIEFNNIO_00313 1.2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LIEFNNIO_00314 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LIEFNNIO_00315 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LIEFNNIO_00316 1.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LIEFNNIO_00317 7e-51 yeaL S Protein of unknown function (DUF441)
LIEFNNIO_00318 9.6e-126 cvfB S S1 domain
LIEFNNIO_00319 9.6e-113 xerD D recombinase XerD
LIEFNNIO_00320 1.9e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
LIEFNNIO_00321 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LIEFNNIO_00322 2.2e-54 nhaC C Na H antiporter NhaC
LIEFNNIO_00323 1.8e-125 nhaC C Na H antiporter NhaC
LIEFNNIO_00324 6e-65 ypsA S Belongs to the UPF0398 family
LIEFNNIO_00325 3.5e-196 ade 3.5.4.2 F Adenine deaminase C-terminal domain
LIEFNNIO_00327 6.3e-73 2.3.1.178 M GNAT acetyltransferase
LIEFNNIO_00328 6.7e-68 maa 2.3.1.79 S Maltose acetyltransferase
LIEFNNIO_00329 2.8e-56 3.6.1.27 I Acid phosphatase homologues
LIEFNNIO_00330 1.1e-80 XK27_07525 3.6.1.55 F Hydrolase, nudix family
LIEFNNIO_00332 4.8e-68 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LIEFNNIO_00333 9.9e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
LIEFNNIO_00334 1.6e-38 K Transcriptional regulator
LIEFNNIO_00335 5.9e-53 EGP Major Facilitator Superfamily
LIEFNNIO_00336 3.1e-167 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LIEFNNIO_00337 1.6e-280 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LIEFNNIO_00338 7.6e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LIEFNNIO_00339 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LIEFNNIO_00341 2.7e-94 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LIEFNNIO_00342 2.2e-44
LIEFNNIO_00343 1.1e-120 ica2 GT2 M Glycosyl transferase family group 2
LIEFNNIO_00344 7.9e-45 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
LIEFNNIO_00345 6.4e-221 mntH P H( )-stimulated, divalent metal cation uptake system
LIEFNNIO_00346 7.6e-61 ypbB 5.1.3.1 S Helix-turn-helix domain
LIEFNNIO_00347 2e-128 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
LIEFNNIO_00348 7.7e-12 M Lysin motif
LIEFNNIO_00349 3.7e-85 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LIEFNNIO_00350 4.4e-83 lytH 3.5.1.28 M Ami_3
LIEFNNIO_00351 5.4e-154 phoH T phosphate starvation-inducible protein PhoH
LIEFNNIO_00352 1.9e-59 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LIEFNNIO_00353 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LIEFNNIO_00354 3.5e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LIEFNNIO_00355 5.9e-90 recO L Involved in DNA repair and RecF pathway recombination
LIEFNNIO_00356 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
LIEFNNIO_00357 3.4e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LIEFNNIO_00358 7e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
LIEFNNIO_00359 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LIEFNNIO_00360 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LIEFNNIO_00361 5.3e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
LIEFNNIO_00362 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
LIEFNNIO_00363 5.9e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LIEFNNIO_00364 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LIEFNNIO_00366 1.8e-22 K Acetyltransferase (GNAT) domain
LIEFNNIO_00367 3.7e-112 natA S Domain of unknown function (DUF4162)
LIEFNNIO_00368 6.5e-80 natB CP ABC-type Na efflux pump, permease component
LIEFNNIO_00369 7e-95 EG EamA-like transporter family
LIEFNNIO_00370 4.5e-80 yjjH S Calcineurin-like phosphoesterase
LIEFNNIO_00371 1.3e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LIEFNNIO_00372 2.4e-40 6.3.3.2 S ASCH
LIEFNNIO_00373 2.5e-69 lepB 3.4.21.89 U Signal peptidase, peptidase S26
LIEFNNIO_00374 8.2e-117 degV S EDD domain protein, DegV family
LIEFNNIO_00375 8.9e-40 K Transcriptional regulator
LIEFNNIO_00376 9.4e-202 FbpA K Fibronectin-binding protein
LIEFNNIO_00377 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LIEFNNIO_00378 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LIEFNNIO_00379 4.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LIEFNNIO_00380 1e-39 ypaA S Protein of unknown function (DUF1304)
LIEFNNIO_00382 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LIEFNNIO_00383 1.5e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LIEFNNIO_00384 0.0 dnaE 2.7.7.7 L DNA polymerase
LIEFNNIO_00385 4.3e-15 S Protein of unknown function (DUF2929)
LIEFNNIO_00386 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LIEFNNIO_00387 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LIEFNNIO_00388 1.4e-40 XK27_04120 S Putative amino acid metabolism
LIEFNNIO_00389 4.6e-160 iscS 2.8.1.7 E Aminotransferase class V
LIEFNNIO_00390 4.6e-91 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LIEFNNIO_00392 2.6e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
LIEFNNIO_00393 3.6e-129 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LIEFNNIO_00394 7.2e-160 nhaC C Na H antiporter NhaC
LIEFNNIO_00395 7e-127 corA P CorA-like Mg2+ transporter protein
LIEFNNIO_00396 1.5e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LIEFNNIO_00397 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
LIEFNNIO_00398 2.8e-150 S Tetratricopeptide repeat protein
LIEFNNIO_00399 4.9e-136 EG EamA-like transporter family
LIEFNNIO_00400 2.5e-70 alkD L DNA alkylation repair enzyme
LIEFNNIO_00401 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LIEFNNIO_00402 1.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LIEFNNIO_00403 1e-77 trmK 2.1.1.217 S SAM-dependent methyltransferase
LIEFNNIO_00404 1.1e-149 EGP Sugar (and other) transporter
LIEFNNIO_00407 6.1e-39
LIEFNNIO_00408 5.9e-257 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
LIEFNNIO_00409 9.5e-22 S Family of unknown function (DUF5322)
LIEFNNIO_00410 1.4e-36 rnhA 3.1.26.4 L Ribonuclease HI
LIEFNNIO_00411 2.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LIEFNNIO_00412 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LIEFNNIO_00414 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LIEFNNIO_00415 4.5e-171 patA 2.6.1.1 E Aminotransferase
LIEFNNIO_00416 8.6e-115 glcR K DeoR C terminal sensor domain
LIEFNNIO_00417 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
LIEFNNIO_00418 1.6e-134 K Transcriptional regulator
LIEFNNIO_00419 9.7e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LIEFNNIO_00420 1.8e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LIEFNNIO_00421 1.5e-190 carB 6.3.5.5 F Carbamoyl-phosphate synthase
LIEFNNIO_00422 2.2e-114 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LIEFNNIO_00423 2.9e-203 pyrP F Permease
LIEFNNIO_00424 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LIEFNNIO_00425 9.6e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LIEFNNIO_00426 2.3e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LIEFNNIO_00427 2.5e-56 3.1.3.18 J HAD-hyrolase-like
LIEFNNIO_00428 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LIEFNNIO_00429 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LIEFNNIO_00430 2.2e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LIEFNNIO_00431 1.5e-118 prmA J Ribosomal protein L11 methyltransferase
LIEFNNIO_00432 3.8e-42 XK27_03960 S Protein of unknown function (DUF3013)
LIEFNNIO_00433 1.1e-143 iunH2 3.2.2.1 F nucleoside hydrolase
LIEFNNIO_00434 1.6e-10
LIEFNNIO_00435 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LIEFNNIO_00436 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
LIEFNNIO_00437 1.2e-128 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LIEFNNIO_00438 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LIEFNNIO_00439 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LIEFNNIO_00440 6.9e-43 yodB K Transcriptional regulator, HxlR family
LIEFNNIO_00441 3.6e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
LIEFNNIO_00442 1.7e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LIEFNNIO_00445 1.7e-15
LIEFNNIO_00447 1.2e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LIEFNNIO_00448 3.3e-41 S Repeat protein
LIEFNNIO_00449 1.8e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
LIEFNNIO_00450 6.7e-72 csm6 S Psort location Cytoplasmic, score
LIEFNNIO_00451 1.1e-31 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LIEFNNIO_00452 1.9e-87 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LIEFNNIO_00453 5e-70 csm5 L RAMP superfamily
LIEFNNIO_00454 5.1e-61 csm4 L CRISPR-associated RAMP protein, Csm4 family
LIEFNNIO_00455 9.8e-70 csm3 L RAMP superfamily
LIEFNNIO_00456 6e-29 csm2 L Csm2 Type III-A
LIEFNNIO_00457 7.2e-205 csm1 S CRISPR-associated protein Csm1 family
LIEFNNIO_00458 6.5e-34 cas6 S Pfam:DUF2276
LIEFNNIO_00459 1.5e-205 G PTS system Galactitol-specific IIC component
LIEFNNIO_00460 1.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LIEFNNIO_00461 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LIEFNNIO_00462 3.3e-86 dprA LU DNA protecting protein DprA
LIEFNNIO_00463 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LIEFNNIO_00464 2.1e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LIEFNNIO_00465 3.6e-24 yozE S Belongs to the UPF0346 family
LIEFNNIO_00466 1.2e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
LIEFNNIO_00467 2.9e-80 ypmR E GDSL-like Lipase/Acylhydrolase
LIEFNNIO_00469 2.1e-113 S Aldo keto reductase
LIEFNNIO_00470 2.7e-34 K helix_turn_helix, mercury resistance
LIEFNNIO_00471 1.8e-132 yvgN C Aldo keto reductase
LIEFNNIO_00472 1.2e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LIEFNNIO_00473 2.6e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LIEFNNIO_00474 5e-276 yfmR S ABC transporter, ATP-binding protein
LIEFNNIO_00475 1.5e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LIEFNNIO_00476 1.4e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LIEFNNIO_00477 1.3e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIEFNNIO_00478 1.8e-68 xerD L Phage integrase, N-terminal SAM-like domain
LIEFNNIO_00480 1.8e-56 yqeY S YqeY-like protein
LIEFNNIO_00481 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LIEFNNIO_00482 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LIEFNNIO_00485 6.8e-101 epsJ1 M Glycosyltransferase like family 2
LIEFNNIO_00486 8e-87 M Glycosyltransferase sugar-binding region containing DXD motif
LIEFNNIO_00487 1.4e-91 M transferase activity, transferring glycosyl groups
LIEFNNIO_00488 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIEFNNIO_00489 7.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LIEFNNIO_00490 1.7e-82 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LIEFNNIO_00491 8.5e-56 dnaD L DnaD domain protein
LIEFNNIO_00492 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
LIEFNNIO_00493 5.8e-142 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LIEFNNIO_00494 1.9e-33 ypmB S Protein conserved in bacteria
LIEFNNIO_00495 3.1e-226 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LIEFNNIO_00496 4e-93 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
LIEFNNIO_00497 3.7e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
LIEFNNIO_00498 1.9e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
LIEFNNIO_00499 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LIEFNNIO_00500 3.5e-103 holA 2.7.7.7 L DNA polymerase III delta subunit
LIEFNNIO_00501 9.4e-157 comEC S Competence protein ComEC
LIEFNNIO_00502 2e-69 comEB 3.5.4.12 F ComE operon protein 2
LIEFNNIO_00503 1.2e-49 comEA L Competence protein ComEA
LIEFNNIO_00504 4.2e-266 argS 6.1.1.19 J Arginyl-tRNA synthetase
LIEFNNIO_00505 4e-58 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LIEFNNIO_00506 2.9e-20
LIEFNNIO_00508 3e-122 K LysR substrate binding domain
LIEFNNIO_00509 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIEFNNIO_00510 2.2e-108 S Acyltransferase family
LIEFNNIO_00511 6.4e-163 purD 6.3.4.13 F Belongs to the GARS family
LIEFNNIO_00512 1.4e-233 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LIEFNNIO_00513 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LIEFNNIO_00514 5.3e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LIEFNNIO_00515 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LIEFNNIO_00516 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LIEFNNIO_00517 1.2e-102 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LIEFNNIO_00518 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LIEFNNIO_00519 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LIEFNNIO_00520 2.4e-131 ylbL T Belongs to the peptidase S16 family
LIEFNNIO_00521 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LIEFNNIO_00522 8e-73 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
LIEFNNIO_00523 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
LIEFNNIO_00524 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LIEFNNIO_00525 2.3e-101 ftsW D Belongs to the SEDS family
LIEFNNIO_00526 3.6e-147 manN G system, mannose fructose sorbose family IID component
LIEFNNIO_00527 3.2e-115 manY G PTS system
LIEFNNIO_00528 1.6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
LIEFNNIO_00529 0.0 typA T GTP-binding protein TypA
LIEFNNIO_00530 2.2e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
LIEFNNIO_00531 1.5e-24 yktA S Belongs to the UPF0223 family
LIEFNNIO_00532 7e-31 1.1.1.27 C L-malate dehydrogenase activity
LIEFNNIO_00533 6.3e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LIEFNNIO_00534 5.5e-25
LIEFNNIO_00535 5e-23 ykzG S Belongs to the UPF0356 family
LIEFNNIO_00536 2.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LIEFNNIO_00537 9.5e-248 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LIEFNNIO_00538 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LIEFNNIO_00539 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LIEFNNIO_00540 8e-216 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LIEFNNIO_00541 1.6e-22 S Tetratricopeptide repeat
LIEFNNIO_00542 3.2e-266 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LIEFNNIO_00543 6.9e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LIEFNNIO_00544 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LIEFNNIO_00545 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
LIEFNNIO_00546 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LIEFNNIO_00547 3.7e-199 yfnA E amino acid
LIEFNNIO_00548 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
LIEFNNIO_00549 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LIEFNNIO_00550 2.5e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LIEFNNIO_00551 1.1e-26 ylqC S Belongs to the UPF0109 family
LIEFNNIO_00552 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LIEFNNIO_00553 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LIEFNNIO_00554 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LIEFNNIO_00555 5.5e-146 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LIEFNNIO_00556 1.8e-210 smc D Required for chromosome condensation and partitioning
LIEFNNIO_00557 3.9e-101 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LIEFNNIO_00558 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LIEFNNIO_00559 1.8e-139 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LIEFNNIO_00560 2.2e-245 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LIEFNNIO_00561 1.3e-238 yloV S DAK2 domain fusion protein YloV
LIEFNNIO_00562 4.5e-53 asp S Asp23 family, cell envelope-related function
LIEFNNIO_00563 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LIEFNNIO_00564 3.5e-59 thiN 2.7.6.2 H thiamine pyrophosphokinase
LIEFNNIO_00565 8.4e-109 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LIEFNNIO_00566 1.8e-192 KLT serine threonine protein kinase
LIEFNNIO_00567 1.9e-90 stp 3.1.3.16 T phosphatase
LIEFNNIO_00568 2e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LIEFNNIO_00569 1.5e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LIEFNNIO_00570 9.2e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LIEFNNIO_00571 7.5e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LIEFNNIO_00572 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LIEFNNIO_00573 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LIEFNNIO_00574 1.9e-94 2.7.1.89 M Phosphotransferase enzyme family
LIEFNNIO_00575 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
LIEFNNIO_00576 1e-186 rodA D Belongs to the SEDS family
LIEFNNIO_00577 1.3e-13 S Protein of unknown function (DUF2969)
LIEFNNIO_00578 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LIEFNNIO_00579 1.3e-166 mbl D Cell shape determining protein MreB Mrl
LIEFNNIO_00580 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LIEFNNIO_00581 4.1e-15 ywzB S Protein of unknown function (DUF1146)
LIEFNNIO_00582 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LIEFNNIO_00583 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LIEFNNIO_00584 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LIEFNNIO_00585 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LIEFNNIO_00586 7e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LIEFNNIO_00587 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LIEFNNIO_00588 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LIEFNNIO_00589 2.6e-97 atpB C it plays a direct role in the translocation of protons across the membrane
LIEFNNIO_00590 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LIEFNNIO_00591 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LIEFNNIO_00592 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LIEFNNIO_00593 1.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LIEFNNIO_00594 2.6e-85 tdk 2.7.1.21 F thymidine kinase
LIEFNNIO_00595 3e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
LIEFNNIO_00596 3.5e-110 cobQ S glutamine amidotransferase
LIEFNNIO_00597 2e-111 ampC V Beta-lactamase
LIEFNNIO_00598 1.5e-31
LIEFNNIO_00599 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LIEFNNIO_00600 4.6e-205 glnP P ABC transporter
LIEFNNIO_00602 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LIEFNNIO_00603 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LIEFNNIO_00604 1.5e-274 dnaK O Heat shock 70 kDa protein
LIEFNNIO_00605 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LIEFNNIO_00606 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LIEFNNIO_00607 1.6e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LIEFNNIO_00608 3.1e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LIEFNNIO_00609 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LIEFNNIO_00610 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LIEFNNIO_00611 3.4e-25 ylxQ J ribosomal protein
LIEFNNIO_00612 1.2e-38 ylxR K Protein of unknown function (DUF448)
LIEFNNIO_00613 3.7e-170 nusA K Participates in both transcription termination and antitermination
LIEFNNIO_00614 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
LIEFNNIO_00615 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LIEFNNIO_00616 1e-259 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LIEFNNIO_00617 5.3e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
LIEFNNIO_00618 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
LIEFNNIO_00619 1.7e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LIEFNNIO_00620 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LIEFNNIO_00621 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LIEFNNIO_00622 2.7e-48 S Domain of unknown function (DUF956)
LIEFNNIO_00623 4.4e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LIEFNNIO_00625 2e-247 glnA 6.3.1.2 E glutamine synthetase
LIEFNNIO_00626 1.3e-45 glnR K Transcriptional regulator
LIEFNNIO_00627 3.6e-206 ynbB 4.4.1.1 P aluminum resistance
LIEFNNIO_00628 2.7e-110 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LIEFNNIO_00629 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
LIEFNNIO_00630 2.7e-46 yqhL P Rhodanese-like protein
LIEFNNIO_00631 6.2e-158 glk 2.7.1.2 G Glucokinase
LIEFNNIO_00632 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
LIEFNNIO_00633 2.4e-68 gluP 3.4.21.105 S Peptidase, S54 family
LIEFNNIO_00634 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LIEFNNIO_00635 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LIEFNNIO_00636 1.3e-19 D nuclear chromosome segregation
LIEFNNIO_00637 2.5e-75 yciQ P membrane protein (DUF2207)
LIEFNNIO_00638 2.1e-43 MA20_27270 S mazG nucleotide pyrophosphohydrolase
LIEFNNIO_00639 1.6e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
LIEFNNIO_00640 2.9e-26 yneF S UPF0154 protein
LIEFNNIO_00641 2.2e-30 ynzC S UPF0291 protein
LIEFNNIO_00642 2.5e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LIEFNNIO_00643 8.7e-176 recN L May be involved in recombinational repair of damaged DNA
LIEFNNIO_00644 6.6e-49 argR K Regulates arginine biosynthesis genes
LIEFNNIO_00645 5.7e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LIEFNNIO_00646 1.6e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LIEFNNIO_00647 9.6e-17 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LIEFNNIO_00648 9.9e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LIEFNNIO_00649 1e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LIEFNNIO_00650 5.5e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LIEFNNIO_00651 1.8e-45 yqhY S Asp23 family, cell envelope-related function
LIEFNNIO_00652 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LIEFNNIO_00653 1.3e-41 dut S dUTPase
LIEFNNIO_00654 5.5e-117
LIEFNNIO_00655 7.3e-105
LIEFNNIO_00656 4.7e-136 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
LIEFNNIO_00657 1.6e-23 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LIEFNNIO_00658 1.8e-117 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LIEFNNIO_00659 3.9e-167 arlS 2.7.13.3 T Histidine kinase
LIEFNNIO_00660 3.1e-111 K response regulator
LIEFNNIO_00662 6.6e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LIEFNNIO_00663 3.5e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LIEFNNIO_00664 7.1e-158 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LIEFNNIO_00665 1.4e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LIEFNNIO_00666 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
LIEFNNIO_00667 6.9e-37
LIEFNNIO_00668 7.9e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LIEFNNIO_00669 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
LIEFNNIO_00670 1.5e-27 yazA L GIY-YIG catalytic domain protein
LIEFNNIO_00671 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
LIEFNNIO_00672 4e-89 plsC 2.3.1.51 I Acyltransferase
LIEFNNIO_00673 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LIEFNNIO_00674 2e-57 yceD S Uncharacterized ACR, COG1399
LIEFNNIO_00675 1e-122 ylbM S Belongs to the UPF0348 family
LIEFNNIO_00676 1.5e-82 H Nodulation protein S (NodS)
LIEFNNIO_00677 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LIEFNNIO_00678 2.6e-69 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
LIEFNNIO_00679 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LIEFNNIO_00680 6e-30 yhbY J RNA-binding protein
LIEFNNIO_00681 1.9e-179 yqeH S Ribosome biogenesis GTPase YqeH
LIEFNNIO_00682 1.2e-70 yqeG S HAD phosphatase, family IIIA
LIEFNNIO_00683 2.2e-52 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LIEFNNIO_00684 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LIEFNNIO_00685 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LIEFNNIO_00686 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LIEFNNIO_00687 1.3e-107 dnaI L Primosomal protein DnaI
LIEFNNIO_00688 1.4e-78 dnaB L replication initiation and membrane attachment
LIEFNNIO_00689 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LIEFNNIO_00690 1.6e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LIEFNNIO_00691 4.3e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LIEFNNIO_00692 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LIEFNNIO_00693 6.7e-69 ybhL S Belongs to the BI1 family
LIEFNNIO_00694 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
LIEFNNIO_00695 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LIEFNNIO_00696 8.2e-192 sftA D Belongs to the FtsK SpoIIIE SftA family
LIEFNNIO_00697 4e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LIEFNNIO_00698 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LIEFNNIO_00700 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LIEFNNIO_00701 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
LIEFNNIO_00702 6.4e-72 ecsB U ABC transporter
LIEFNNIO_00703 1.3e-94 ecsA V ABC transporter, ATP-binding protein
LIEFNNIO_00704 7e-53 hit FG histidine triad
LIEFNNIO_00706 3.3e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LIEFNNIO_00707 8.6e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
LIEFNNIO_00708 2e-21 yheA S Belongs to the UPF0342 family
LIEFNNIO_00709 3e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LIEFNNIO_00711 9e-87 ykuT M mechanosensitive ion channel
LIEFNNIO_00712 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LIEFNNIO_00713 3.9e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LIEFNNIO_00714 5.8e-45 ykuL S CBS domain
LIEFNNIO_00715 5.7e-119 gla U Major intrinsic protein
LIEFNNIO_00716 1.3e-301 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LIEFNNIO_00717 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
LIEFNNIO_00718 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LIEFNNIO_00719 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
LIEFNNIO_00720 4.4e-101 accA 2.1.3.15, 6.4.1.2 I alpha subunit
LIEFNNIO_00721 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LIEFNNIO_00722 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
LIEFNNIO_00723 3.9e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LIEFNNIO_00724 4.6e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LIEFNNIO_00725 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LIEFNNIO_00726 2.5e-98 IQ reductase
LIEFNNIO_00727 2.9e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
LIEFNNIO_00728 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LIEFNNIO_00729 2.9e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIEFNNIO_00730 4.2e-61 marR K Transcriptional regulator, MarR family
LIEFNNIO_00731 3.4e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LIEFNNIO_00732 5.2e-36
LIEFNNIO_00734 3e-193 pepV 3.5.1.18 E dipeptidase PepV
LIEFNNIO_00735 1.2e-80 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LIEFNNIO_00736 5.2e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LIEFNNIO_00737 6.4e-187 ytgP S Polysaccharide biosynthesis protein
LIEFNNIO_00738 2.4e-192 cycA E Amino acid permease
LIEFNNIO_00739 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LIEFNNIO_00740 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LIEFNNIO_00741 1.3e-06 M MucBP domain
LIEFNNIO_00742 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
LIEFNNIO_00743 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
LIEFNNIO_00744 9e-181 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LIEFNNIO_00745 1.5e-229 lpdA 1.8.1.4 C Dehydrogenase
LIEFNNIO_00746 1.2e-148 lplA 6.3.1.20 H Lipoate-protein ligase
LIEFNNIO_00747 9.2e-56 S Protein of unknown function (DUF975)
LIEFNNIO_00748 1.4e-76 E GDSL-like Lipase/Acylhydrolase family
LIEFNNIO_00749 8.9e-38
LIEFNNIO_00750 4.1e-27 gcvR T Belongs to the UPF0237 family
LIEFNNIO_00751 3e-219 XK27_08635 S UPF0210 protein
LIEFNNIO_00752 2.2e-86 fruR K DeoR C terminal sensor domain
LIEFNNIO_00753 4.5e-150 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LIEFNNIO_00754 2.3e-300 fruA 2.7.1.202 GT Phosphotransferase System
LIEFNNIO_00755 2e-49 cps3F
LIEFNNIO_00756 6e-83 S Membrane
LIEFNNIO_00757 5.3e-254 E Amino acid permease
LIEFNNIO_00758 9.3e-232 cadA P P-type ATPase
LIEFNNIO_00759 1.9e-113 degV S EDD domain protein, DegV family
LIEFNNIO_00760 9.6e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
LIEFNNIO_00761 4.7e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
LIEFNNIO_00762 7.2e-27 ydiI Q Thioesterase superfamily
LIEFNNIO_00763 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LIEFNNIO_00764 7.8e-141 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LIEFNNIO_00765 5.6e-82 S L,D-transpeptidase catalytic domain
LIEFNNIO_00766 2.1e-164 EGP Major facilitator Superfamily
LIEFNNIO_00767 7.4e-20 K helix_turn_helix multiple antibiotic resistance protein
LIEFNNIO_00768 1.2e-223 pipD E Dipeptidase
LIEFNNIO_00769 4.3e-123 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LIEFNNIO_00770 2.6e-32 ywjH S Protein of unknown function (DUF1634)
LIEFNNIO_00771 1.7e-119 yxaA S membrane transporter protein
LIEFNNIO_00772 4.5e-83 lysR5 K LysR substrate binding domain
LIEFNNIO_00773 9.4e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
LIEFNNIO_00774 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIEFNNIO_00775 2.5e-271 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LIEFNNIO_00776 6.8e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
LIEFNNIO_00777 7.2e-243 lysP E amino acid
LIEFNNIO_00778 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LIEFNNIO_00782 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
LIEFNNIO_00783 2.3e-46 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LIEFNNIO_00784 6.6e-69 coiA 3.6.4.12 S Competence protein
LIEFNNIO_00785 1.2e-229 pepF E oligoendopeptidase F
LIEFNNIO_00786 2.3e-41 yjbH Q Thioredoxin
LIEFNNIO_00787 1.9e-97 pstS P Phosphate
LIEFNNIO_00788 7e-119 pstC P probably responsible for the translocation of the substrate across the membrane
LIEFNNIO_00789 3.9e-122 pstA P Phosphate transport system permease protein PstA
LIEFNNIO_00790 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LIEFNNIO_00791 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LIEFNNIO_00792 3.6e-56 P Plays a role in the regulation of phosphate uptake
LIEFNNIO_00793 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
LIEFNNIO_00794 1.1e-79 S VIT family
LIEFNNIO_00795 9.4e-84 S membrane
LIEFNNIO_00796 1.1e-39 M1-874 K Domain of unknown function (DUF1836)
LIEFNNIO_00797 1.8e-65 hly S protein, hemolysin III
LIEFNNIO_00798 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
LIEFNNIO_00799 1.3e-74 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LIEFNNIO_00802 5.1e-14
LIEFNNIO_00803 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LIEFNNIO_00804 1.1e-157 ccpA K catabolite control protein A
LIEFNNIO_00805 1.1e-41 S VanZ like family
LIEFNNIO_00806 1.5e-119 yebC K Transcriptional regulatory protein
LIEFNNIO_00807 1.5e-100 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LIEFNNIO_00808 1.1e-120 comGA NU Type II IV secretion system protein
LIEFNNIO_00809 3.4e-98 comGB NU type II secretion system
LIEFNNIO_00810 1.8e-26 comGC U competence protein ComGC
LIEFNNIO_00811 5e-14
LIEFNNIO_00813 1.6e-10 S Putative Competence protein ComGF
LIEFNNIO_00815 5.8e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
LIEFNNIO_00816 2.7e-183 cycA E Amino acid permease
LIEFNNIO_00817 3e-57 S Calcineurin-like phosphoesterase
LIEFNNIO_00818 1.9e-53 yutD S Protein of unknown function (DUF1027)
LIEFNNIO_00819 8.3e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LIEFNNIO_00820 4.6e-32 S Protein of unknown function (DUF1461)
LIEFNNIO_00821 3e-92 dedA S SNARE associated Golgi protein
LIEFNNIO_00822 2.3e-94 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LIEFNNIO_00823 1.1e-49 yugI 5.3.1.9 J general stress protein
LIEFNNIO_00824 4.6e-79
LIEFNNIO_00825 8.7e-51 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LIEFNNIO_00826 3.9e-259 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
LIEFNNIO_00827 0.0 M Cna protein B-type domain
LIEFNNIO_00828 8.5e-89 2.7.7.65 T phosphorelay sensor kinase activity
LIEFNNIO_00829 1.3e-132 cbiQ P Cobalt transport protein
LIEFNNIO_00830 6e-157 P ABC transporter
LIEFNNIO_00831 1.5e-149 cbiO2 P ABC transporter
LIEFNNIO_00832 2.2e-261 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LIEFNNIO_00833 4.9e-179 proV E ABC transporter, ATP-binding protein
LIEFNNIO_00834 8.9e-248 gshR 1.8.1.7 C Glutathione reductase
LIEFNNIO_00835 6.5e-102 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
LIEFNNIO_00836 1.3e-106
LIEFNNIO_00837 3.5e-40 S RelB antitoxin
LIEFNNIO_00838 1e-34
LIEFNNIO_00839 7e-183 L Probable transposase
LIEFNNIO_00841 5.8e-62 norB EGP Major Facilitator
LIEFNNIO_00842 2.4e-101 tag 3.2.2.20 L Methyladenine glycosylase
LIEFNNIO_00843 3e-235 stp_1 EGP Major facilitator Superfamily
LIEFNNIO_00844 5.9e-70 H ThiF family
LIEFNNIO_00845 5.4e-206 arsR K DNA-binding transcription factor activity
LIEFNNIO_00846 8.9e-96 K Transcriptional regulator
LIEFNNIO_00847 2.5e-31 L Transposase
LIEFNNIO_00848 2.7e-171 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LIEFNNIO_00849 8.5e-64 V HNH endonuclease
LIEFNNIO_00851 4e-31 tnp L MULE transposase domain
LIEFNNIO_00852 5.2e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
LIEFNNIO_00853 1.3e-54 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
LIEFNNIO_00854 5.4e-147 D CobQ CobB MinD ParA nucleotide binding domain protein
LIEFNNIO_00855 8.5e-35
LIEFNNIO_00856 1.5e-168 repA S Replication initiator protein A
LIEFNNIO_00857 4.5e-132 S Fic/DOC family
LIEFNNIO_00858 2.9e-39 relB L Addiction module antitoxin, RelB DinJ family
LIEFNNIO_00859 1.2e-25
LIEFNNIO_00860 4.3e-113 S protein conserved in bacteria
LIEFNNIO_00861 3.4e-40
LIEFNNIO_00862 1.4e-25
LIEFNNIO_00863 0.0 L MobA MobL family protein
LIEFNNIO_00864 1.1e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
LIEFNNIO_00865 3.8e-93
LIEFNNIO_00866 3.1e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
LIEFNNIO_00867 4.7e-271 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LIEFNNIO_00868 2.3e-101 pncA Q Isochorismatase family
LIEFNNIO_00869 2.5e-104 L Helix-turn-helix domain
LIEFNNIO_00870 1.6e-111 L hmm pf00665
LIEFNNIO_00871 4e-24 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LIEFNNIO_00872 1.3e-89 saeS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
LIEFNNIO_00873 5.1e-77 K response regulator
LIEFNNIO_00875 1.9e-158 L Transposase
LIEFNNIO_00876 3.7e-11 S Protein of unknown function (DUF3021)
LIEFNNIO_00878 4.1e-60 cylB V ABC-2 type transporter
LIEFNNIO_00879 3.5e-75 cylA V abc transporter atp-binding protein
LIEFNNIO_00881 6.9e-57 K SIR2-like domain
LIEFNNIO_00882 9.3e-21
LIEFNNIO_00896 2.1e-07
LIEFNNIO_00898 1.7e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LIEFNNIO_00899 1.4e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LIEFNNIO_00900 1.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LIEFNNIO_00901 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
LIEFNNIO_00902 2.5e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LIEFNNIO_00904 1.6e-55 ctsR K Belongs to the CtsR family
LIEFNNIO_00905 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LIEFNNIO_00906 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LIEFNNIO_00907 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LIEFNNIO_00908 1.9e-23 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
LIEFNNIO_00909 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LIEFNNIO_00910 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LIEFNNIO_00911 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LIEFNNIO_00912 9e-93 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LIEFNNIO_00913 6.8e-90 patB 4.4.1.8 E Aminotransferase, class I
LIEFNNIO_00914 1.4e-111 K response regulator
LIEFNNIO_00915 8.8e-143 hpk31 2.7.13.3 T Histidine kinase
LIEFNNIO_00916 2.5e-89 lacX 5.1.3.3 G Aldose 1-epimerase
LIEFNNIO_00917 1e-146 G Transporter, major facilitator family protein
LIEFNNIO_00918 2.9e-222 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LIEFNNIO_00919 4e-244 yhcA V ABC transporter, ATP-binding protein
LIEFNNIO_00920 3.8e-34 K Bacterial regulatory proteins, tetR family
LIEFNNIO_00921 1.3e-222 lmrA V ABC transporter, ATP-binding protein
LIEFNNIO_00922 3.3e-253 yfiC V ABC transporter
LIEFNNIO_00924 1.1e-45 yjcF K protein acetylation
LIEFNNIO_00925 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
LIEFNNIO_00926 3e-72 lemA S LemA family
LIEFNNIO_00927 1.7e-109 htpX O Belongs to the peptidase M48B family
LIEFNNIO_00929 1.4e-269 helD 3.6.4.12 L DNA helicase
LIEFNNIO_00930 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LIEFNNIO_00931 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
LIEFNNIO_00932 1.6e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
LIEFNNIO_00933 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
LIEFNNIO_00934 2.4e-105 ybhR V ABC transporter
LIEFNNIO_00935 3.9e-31 K Transcriptional regulator
LIEFNNIO_00936 4.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
LIEFNNIO_00937 1.8e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
LIEFNNIO_00938 5.6e-127
LIEFNNIO_00939 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LIEFNNIO_00940 1.7e-102 tatD L hydrolase, TatD family
LIEFNNIO_00941 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LIEFNNIO_00942 1.4e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LIEFNNIO_00943 1.2e-22 veg S Biofilm formation stimulator VEG
LIEFNNIO_00944 5.7e-91 S Alpha/beta hydrolase of unknown function (DUF915)
LIEFNNIO_00945 1e-132 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
LIEFNNIO_00946 6.6e-46 argR K Regulates arginine biosynthesis genes
LIEFNNIO_00947 8.2e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LIEFNNIO_00948 6.7e-155 amtB P ammonium transporter
LIEFNNIO_00949 6.6e-90 sip L Belongs to the 'phage' integrase family
LIEFNNIO_00950 1.9e-31 S ParE toxin of type II toxin-antitoxin system, parDE
LIEFNNIO_00951 9.7e-23
LIEFNNIO_00953 2.6e-24 S Domain of unknown function (DUF4393)
LIEFNNIO_00954 2.2e-31
LIEFNNIO_00955 9.9e-27 S Domain of unknown function (DUF4352)
LIEFNNIO_00958 4.5e-42 K Peptidase S24-like
LIEFNNIO_00962 5.9e-16
LIEFNNIO_00964 2.6e-15 K Cro/C1-type HTH DNA-binding domain
LIEFNNIO_00965 2.4e-13 cro K Helix-turn-helix XRE-family like proteins
LIEFNNIO_00966 4.6e-81 S DNA binding
LIEFNNIO_00971 1.7e-54 S Putative HNHc nuclease
LIEFNNIO_00972 8.6e-30 S Phage replisome organizer, N-terminal domain protein
LIEFNNIO_00975 1.6e-25
LIEFNNIO_00976 2.2e-70
LIEFNNIO_00982 7.8e-21
LIEFNNIO_00984 1.5e-59 Q DNA (cytosine-5-)-methyltransferase activity
LIEFNNIO_00988 2.3e-28 arpU S Phage transcriptional regulator, ArpU family
LIEFNNIO_00989 8.8e-12
LIEFNNIO_00992 3.9e-66 L HNH nucleases
LIEFNNIO_00993 5.3e-81 L Phage terminase, small subunit
LIEFNNIO_00994 0.0 S Phage Terminase
LIEFNNIO_00996 1.9e-193 S Phage portal protein
LIEFNNIO_00997 1e-112 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
LIEFNNIO_00998 6.5e-197 S Phage capsid family
LIEFNNIO_00999 3.7e-22 S Phage gp6-like head-tail connector protein
LIEFNNIO_01000 1.3e-49 S Phage head-tail joining protein
LIEFNNIO_01001 4.8e-54 S Bacteriophage HK97-gp10, putative tail-component
LIEFNNIO_01002 7.8e-56 S Protein of unknown function (DUF806)
LIEFNNIO_01003 1.8e-77 S Phage tail tube protein
LIEFNNIO_01004 9.8e-17 S Phage tail assembly chaperone proteins, TAC
LIEFNNIO_01006 2.2e-304 M Phage tail tape measure protein TP901
LIEFNNIO_01007 1.3e-76 S Phage tail protein
LIEFNNIO_01008 1.7e-116 rny D peptidase
LIEFNNIO_01010 1.9e-27 S Calcineurin-like phosphoesterase
LIEFNNIO_01017 1.9e-130 M Glycosyl hydrolases family 25
LIEFNNIO_01018 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
LIEFNNIO_01019 1.7e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LIEFNNIO_01020 3.4e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
LIEFNNIO_01021 9.9e-127 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LIEFNNIO_01022 4.7e-103 pfoS S Phosphotransferase system, EIIC
LIEFNNIO_01023 4.6e-73 2.4.1.9 GH68 M MucBP domain
LIEFNNIO_01024 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LIEFNNIO_01025 9.6e-52 adhR K helix_turn_helix, mercury resistance
LIEFNNIO_01026 5.2e-137 purR 2.4.2.7 F pur operon repressor
LIEFNNIO_01027 4.3e-47 EGP Transmembrane secretion effector
LIEFNNIO_01028 1.5e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LIEFNNIO_01029 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LIEFNNIO_01030 4.3e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIEFNNIO_01032 3.1e-113 dkg S reductase
LIEFNNIO_01033 9e-26
LIEFNNIO_01034 5.1e-78 2.4.2.3 F Phosphorylase superfamily
LIEFNNIO_01035 3.9e-290 ybiT S ABC transporter, ATP-binding protein
LIEFNNIO_01036 5.7e-62 bCE_4747 S Beta-lactamase superfamily domain
LIEFNNIO_01037 1.7e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LIEFNNIO_01038 3.9e-124 S overlaps another CDS with the same product name
LIEFNNIO_01039 2.6e-87 S overlaps another CDS with the same product name
LIEFNNIO_01041 1.7e-44 spoVK O ATPase family associated with various cellular activities (AAA)
LIEFNNIO_01043 1e-22
LIEFNNIO_01045 5.5e-26 L PIF1-like helicase
LIEFNNIO_01047 1.7e-71
LIEFNNIO_01048 3.7e-22
LIEFNNIO_01049 3.2e-103 ydcZ S Putative inner membrane exporter, YdcZ
LIEFNNIO_01050 4e-89 S hydrolase
LIEFNNIO_01051 4.3e-205 ywfO S HD domain protein
LIEFNNIO_01052 7.5e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
LIEFNNIO_01053 3.1e-32 ywiB S Domain of unknown function (DUF1934)
LIEFNNIO_01054 9.9e-42 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LIEFNNIO_01055 6.2e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LIEFNNIO_01058 4.6e-201 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LIEFNNIO_01059 3.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LIEFNNIO_01060 3.6e-41 rpmE2 J Ribosomal protein L31
LIEFNNIO_01061 2.8e-61
LIEFNNIO_01062 2.6e-258 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
LIEFNNIO_01064 8e-79 S Cell surface protein
LIEFNNIO_01066 1.6e-180 pbuG S permease
LIEFNNIO_01067 4.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
LIEFNNIO_01068 5.3e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LIEFNNIO_01069 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LIEFNNIO_01070 1e-29 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LIEFNNIO_01071 8.2e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LIEFNNIO_01072 5.4e-13
LIEFNNIO_01073 2e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
LIEFNNIO_01074 1.5e-91 yunF F Protein of unknown function DUF72
LIEFNNIO_01075 6.6e-156 nrnB S DHHA1 domain
LIEFNNIO_01076 1.4e-42 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LIEFNNIO_01077 4.4e-60
LIEFNNIO_01078 7.3e-47 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
LIEFNNIO_01079 7e-23 S Cytochrome B5
LIEFNNIO_01080 1.8e-19 sigH K DNA-templated transcription, initiation
LIEFNNIO_01081 4.2e-67 recX 2.4.1.337 GT4 S Regulatory protein RecX
LIEFNNIO_01082 4.7e-191 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LIEFNNIO_01083 2.6e-97 ygaC J Belongs to the UPF0374 family
LIEFNNIO_01084 6.9e-92 yueF S AI-2E family transporter
LIEFNNIO_01085 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LIEFNNIO_01086 1e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LIEFNNIO_01087 2e-278 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LIEFNNIO_01088 0.0 lacL 3.2.1.23 G -beta-galactosidase
LIEFNNIO_01089 8.9e-289 lacS G Transporter
LIEFNNIO_01090 5.9e-111 galR K Transcriptional regulator
LIEFNNIO_01091 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LIEFNNIO_01092 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LIEFNNIO_01093 8.3e-202 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LIEFNNIO_01094 0.0 rafA 3.2.1.22 G alpha-galactosidase
LIEFNNIO_01095 1.1e-104 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
LIEFNNIO_01096 1.9e-22 XK27_09445 S Domain of unknown function (DUF1827)
LIEFNNIO_01097 0.0 clpE O Belongs to the ClpA ClpB family
LIEFNNIO_01098 1.5e-15
LIEFNNIO_01099 9.7e-37 ptsH G phosphocarrier protein HPR
LIEFNNIO_01100 9e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LIEFNNIO_01101 1.1e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
LIEFNNIO_01102 1.3e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
LIEFNNIO_01103 1.3e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LIEFNNIO_01104 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
LIEFNNIO_01105 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LIEFNNIO_01108 1.6e-75 xerC L Belongs to the 'phage' integrase family
LIEFNNIO_01109 1.8e-27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LIEFNNIO_01110 8.4e-38 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LIEFNNIO_01111 2.5e-58 cpsF M Oligosaccharide biosynthesis protein Alg14 like
LIEFNNIO_01112 2e-91 rfbP M Bacterial sugar transferase
LIEFNNIO_01113 2.7e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LIEFNNIO_01114 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LIEFNNIO_01115 1.6e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LIEFNNIO_01116 4e-129 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LIEFNNIO_01118 1.2e-66 M Peptidase family M23
LIEFNNIO_01119 6.2e-43 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LIEFNNIO_01120 6.9e-92 M Core-2/I-Branching enzyme
LIEFNNIO_01121 1.3e-76 waaB GT4 M Glycosyl transferases group 1
LIEFNNIO_01122 3.4e-93 M transferase activity, transferring glycosyl groups
LIEFNNIO_01123 1.1e-57 cps3F
LIEFNNIO_01124 2.4e-73 M LicD family
LIEFNNIO_01125 2.5e-63 M Glycosyltransferase like family 2
LIEFNNIO_01128 1e-43 S Peptidase_C39 like family
LIEFNNIO_01129 1.1e-16 S Acyltransferase family
LIEFNNIO_01130 1.1e-22 S Acyltransferase family
LIEFNNIO_01131 1.2e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
LIEFNNIO_01132 1.8e-153 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
LIEFNNIO_01134 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LIEFNNIO_01135 7.3e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LIEFNNIO_01136 5.6e-97 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LIEFNNIO_01137 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
LIEFNNIO_01138 7e-157 XK27_09615 S reductase
LIEFNNIO_01139 7.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
LIEFNNIO_01140 5e-147 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
LIEFNNIO_01141 8.5e-37 S Psort location CytoplasmicMembrane, score
LIEFNNIO_01142 1.6e-35 S Psort location CytoplasmicMembrane, score
LIEFNNIO_01143 3.6e-14
LIEFNNIO_01144 9.1e-132 S Bacterial membrane protein YfhO
LIEFNNIO_01145 6e-176 thrC 4.2.3.1 E Threonine synthase
LIEFNNIO_01146 1.5e-127 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LIEFNNIO_01147 1.2e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
LIEFNNIO_01148 1.2e-88 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LIEFNNIO_01149 2.2e-177 licA 2.7.1.89 M Choline/ethanolamine kinase
LIEFNNIO_01150 1.9e-84 M Nucleotidyl transferase
LIEFNNIO_01151 1.1e-150 M BCCT, betaine/carnitine/choline family transporter
LIEFNNIO_01152 5.9e-56 S peptidoglycan catabolic process
LIEFNNIO_01153 2.1e-196 XK27_08315 M Sulfatase
LIEFNNIO_01155 1.4e-167 mdtG EGP Major facilitator Superfamily
LIEFNNIO_01156 9.8e-252 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
LIEFNNIO_01157 6.3e-83 treR K UTRA
LIEFNNIO_01158 9.5e-259 treB G phosphotransferase system
LIEFNNIO_01159 4.6e-63 3.1.3.73 G phosphoglycerate mutase
LIEFNNIO_01160 7e-82 pncA Q isochorismatase
LIEFNNIO_01161 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
LIEFNNIO_01162 3.4e-103 ydhQ K UbiC transcription regulator-associated domain protein
LIEFNNIO_01163 5e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LIEFNNIO_01164 1.3e-41 K Transcriptional regulator, HxlR family
LIEFNNIO_01165 3.2e-163 C Luciferase-like monooxygenase
LIEFNNIO_01166 5e-67 1.5.1.38 S NADPH-dependent FMN reductase
LIEFNNIO_01167 7.6e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
LIEFNNIO_01168 4.4e-75 L haloacid dehalogenase-like hydrolase
LIEFNNIO_01169 5.8e-60 EG EamA-like transporter family
LIEFNNIO_01170 4e-118 K AI-2E family transporter
LIEFNNIO_01171 1.9e-172 malY 4.4.1.8 E Aminotransferase, class I
LIEFNNIO_01172 4.6e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LIEFNNIO_01173 2.3e-59 yfjR K WYL domain
LIEFNNIO_01174 4e-11 S Mor transcription activator family
LIEFNNIO_01176 8.1e-09 S zinc-ribbon domain
LIEFNNIO_01181 9.2e-91 V domain protein
LIEFNNIO_01182 4.9e-119 xth 3.1.11.2 L exodeoxyribonuclease III
LIEFNNIO_01183 3.5e-17
LIEFNNIO_01184 1.9e-104 azlC E AzlC protein
LIEFNNIO_01185 1.3e-38 azlD S branched-chain amino acid
LIEFNNIO_01186 2.1e-66 I alpha/beta hydrolase fold
LIEFNNIO_01187 3.1e-25
LIEFNNIO_01188 2.1e-58 3.6.1.27 I phosphatase
LIEFNNIO_01189 3.1e-23
LIEFNNIO_01190 3.1e-95 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
LIEFNNIO_01191 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
LIEFNNIO_01192 3.1e-27 cspC K Cold shock protein
LIEFNNIO_01193 4.3e-82 thrE S Putative threonine/serine exporter
LIEFNNIO_01194 1.3e-49 S Threonine/Serine exporter, ThrE
LIEFNNIO_01195 2.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LIEFNNIO_01196 3.8e-87 S Sucrose-6F-phosphate phosphohydrolase
LIEFNNIO_01197 1.9e-34 trxA O Belongs to the thioredoxin family
LIEFNNIO_01198 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LIEFNNIO_01199 8.8e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LIEFNNIO_01200 4.3e-65 degV S Uncharacterised protein, DegV family COG1307
LIEFNNIO_01202 4.3e-54 queT S QueT transporter
LIEFNNIO_01203 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
LIEFNNIO_01204 1.4e-101 IQ Enoyl-(Acyl carrier protein) reductase
LIEFNNIO_01205 1.3e-111 argE 3.5.1.18 E Peptidase dimerisation domain
LIEFNNIO_01206 2.1e-173 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LIEFNNIO_01207 4.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LIEFNNIO_01208 5e-87 S Alpha beta hydrolase
LIEFNNIO_01209 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LIEFNNIO_01210 1.6e-140 V MatE
LIEFNNIO_01211 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
LIEFNNIO_01212 3.4e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LIEFNNIO_01213 3.3e-97 V ABC transporter
LIEFNNIO_01214 1.6e-131 bacI V MacB-like periplasmic core domain
LIEFNNIO_01215 6.9e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LIEFNNIO_01216 3.7e-26
LIEFNNIO_01217 9.3e-181 yhdP S Transporter associated domain
LIEFNNIO_01218 6e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
LIEFNNIO_01219 0.0 L Helicase C-terminal domain protein
LIEFNNIO_01220 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LIEFNNIO_01221 6.3e-212 yfnA E Amino Acid
LIEFNNIO_01222 3.2e-53 zur P Belongs to the Fur family
LIEFNNIO_01224 2.9e-98
LIEFNNIO_01225 3.9e-08
LIEFNNIO_01226 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LIEFNNIO_01227 4.6e-101 glnH ET ABC transporter
LIEFNNIO_01228 9.3e-86 gluC P ABC transporter permease
LIEFNNIO_01229 9.6e-78 glnP P ABC transporter permease
LIEFNNIO_01230 1.1e-181 steT E amino acid
LIEFNNIO_01231 3.8e-21 K Acetyltransferase (GNAT) domain
LIEFNNIO_01233 1.2e-164 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LIEFNNIO_01234 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LIEFNNIO_01235 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LIEFNNIO_01236 1e-100 rplD J Forms part of the polypeptide exit tunnel
LIEFNNIO_01237 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LIEFNNIO_01238 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LIEFNNIO_01239 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LIEFNNIO_01240 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LIEFNNIO_01241 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LIEFNNIO_01242 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LIEFNNIO_01243 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
LIEFNNIO_01244 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LIEFNNIO_01245 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LIEFNNIO_01246 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LIEFNNIO_01247 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LIEFNNIO_01248 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LIEFNNIO_01249 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LIEFNNIO_01250 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LIEFNNIO_01251 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LIEFNNIO_01252 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LIEFNNIO_01253 2.1e-22 rpmD J Ribosomal protein L30
LIEFNNIO_01254 1e-67 rplO J Binds to the 23S rRNA
LIEFNNIO_01255 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LIEFNNIO_01256 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LIEFNNIO_01257 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LIEFNNIO_01258 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LIEFNNIO_01259 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LIEFNNIO_01260 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LIEFNNIO_01261 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LIEFNNIO_01262 4.8e-53 rplQ J Ribosomal protein L17
LIEFNNIO_01263 4e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LIEFNNIO_01264 1.5e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LIEFNNIO_01265 3.7e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LIEFNNIO_01266 5.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LIEFNNIO_01267 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LIEFNNIO_01268 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
LIEFNNIO_01269 1.4e-30
LIEFNNIO_01270 1.2e-245 yjbQ P TrkA C-terminal domain protein
LIEFNNIO_01271 0.0 helD 3.6.4.12 L DNA helicase
LIEFNNIO_01272 2.3e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
LIEFNNIO_01273 9.6e-112 hrtB V ABC transporter permease
LIEFNNIO_01274 4.6e-35 ygfC K Bacterial regulatory proteins, tetR family
LIEFNNIO_01275 4.3e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LIEFNNIO_01276 2.5e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LIEFNNIO_01277 4.6e-36 M LysM domain protein
LIEFNNIO_01278 8.9e-116 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LIEFNNIO_01279 3.5e-101 sbcC L Putative exonuclease SbcCD, C subunit
LIEFNNIO_01280 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
LIEFNNIO_01281 7.2e-53 perR P Belongs to the Fur family
LIEFNNIO_01282 2.9e-208 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LIEFNNIO_01283 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LIEFNNIO_01284 2.5e-86 S (CBS) domain
LIEFNNIO_01285 3.6e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LIEFNNIO_01286 5.5e-74 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LIEFNNIO_01287 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LIEFNNIO_01288 6.6e-141 yabM S Polysaccharide biosynthesis protein
LIEFNNIO_01289 3.6e-31 yabO J S4 domain protein
LIEFNNIO_01290 1e-21 divIC D Septum formation initiator
LIEFNNIO_01291 1.1e-40 yabR J RNA binding
LIEFNNIO_01292 3.6e-95 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LIEFNNIO_01293 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LIEFNNIO_01294 1.5e-281 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LIEFNNIO_01295 2e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LIEFNNIO_01296 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LIEFNNIO_01297 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LIEFNNIO_01300 6.1e-07
LIEFNNIO_01301 3.9e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LIEFNNIO_01302 1.7e-54 rplI J Binds to the 23S rRNA
LIEFNNIO_01303 3.6e-207 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LIEFNNIO_01304 4e-64 C FMN binding
LIEFNNIO_01305 9.6e-231 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LIEFNNIO_01307 1.5e-156 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LIEFNNIO_01308 1.6e-59 ykhA 3.1.2.20 I Thioesterase superfamily
LIEFNNIO_01309 1.9e-10 S CAAX protease self-immunity
LIEFNNIO_01310 2.5e-82 S Belongs to the UPF0246 family
LIEFNNIO_01311 3.5e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
LIEFNNIO_01312 1.1e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
LIEFNNIO_01313 4.9e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
LIEFNNIO_01314 5.3e-197 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
LIEFNNIO_01315 7.1e-160 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
LIEFNNIO_01316 1.7e-56 3.1.3.48 K Transcriptional regulator
LIEFNNIO_01317 9e-198 1.3.5.4 C FMN_bind
LIEFNNIO_01318 1.9e-116 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
LIEFNNIO_01319 9.9e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
LIEFNNIO_01320 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LIEFNNIO_01321 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
LIEFNNIO_01322 5.8e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
LIEFNNIO_01323 7.8e-90 G PTS system sorbose-specific iic component
LIEFNNIO_01324 7.1e-123 G PTS system mannose/fructose/sorbose family IID component
LIEFNNIO_01325 7.5e-39 2.7.1.191 G PTS system fructose IIA component
LIEFNNIO_01326 4.2e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
LIEFNNIO_01327 1.8e-112 lacI3 K helix_turn _helix lactose operon repressor
LIEFNNIO_01328 1.3e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
LIEFNNIO_01329 5e-77 hchA S intracellular protease amidase
LIEFNNIO_01330 1.2e-21 K transcriptional regulator
LIEFNNIO_01331 2.8e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LIEFNNIO_01332 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
LIEFNNIO_01333 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
LIEFNNIO_01334 2.1e-250 ctpA 3.6.3.54 P P-type ATPase
LIEFNNIO_01335 1.4e-65 pgm3 G phosphoglycerate mutase family
LIEFNNIO_01336 3.9e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
LIEFNNIO_01337 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LIEFNNIO_01338 2.3e-217 yifK E Amino acid permease
LIEFNNIO_01339 4.7e-203 oppA E ABC transporter, substratebinding protein
LIEFNNIO_01340 4.6e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
LIEFNNIO_01341 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LIEFNNIO_01342 1.3e-180 oppD P Belongs to the ABC transporter superfamily
LIEFNNIO_01343 2.2e-155 oppF P Belongs to the ABC transporter superfamily
LIEFNNIO_01344 9.2e-16 psiE S Phosphate-starvation-inducible E
LIEFNNIO_01345 2.4e-208 mmuP E amino acid
LIEFNNIO_01346 9e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
LIEFNNIO_01347 4.5e-39 K LytTr DNA-binding domain
LIEFNNIO_01348 6.6e-17 S Protein of unknown function (DUF3021)
LIEFNNIO_01349 1.2e-150 yfeX P Peroxidase
LIEFNNIO_01350 3e-30 tetR K Transcriptional regulator C-terminal region
LIEFNNIO_01351 4.1e-47 S Short repeat of unknown function (DUF308)
LIEFNNIO_01352 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LIEFNNIO_01353 6.2e-163 oxlT P Major Facilitator Superfamily
LIEFNNIO_01354 2.6e-67 ybbL S ABC transporter
LIEFNNIO_01355 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
LIEFNNIO_01356 4.2e-43 ytcD K HxlR-like helix-turn-helix
LIEFNNIO_01357 8.4e-119 ytbE S reductase
LIEFNNIO_01358 1.1e-70 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LIEFNNIO_01360 1.6e-15
LIEFNNIO_01361 3.2e-34 tetR K transcriptional regulator
LIEFNNIO_01362 7.1e-95 XK27_06785 V ABC transporter, ATP-binding protein
LIEFNNIO_01363 3.4e-148 XK27_06780 V ABC transporter permease
LIEFNNIO_01364 6.3e-85 XK27_06780 V ABC transporter permease
LIEFNNIO_01365 1.3e-37 aguA_2 3.5.3.12 E Porphyromonas-type peptidyl-arginine deiminase
LIEFNNIO_01367 1.3e-40 wecD K Acetyltransferase GNAT Family
LIEFNNIO_01368 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
LIEFNNIO_01369 8.6e-71 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
LIEFNNIO_01370 2.1e-07 yvaZ S SdpI/YhfL protein family
LIEFNNIO_01371 5e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
LIEFNNIO_01372 2e-285 pepO 3.4.24.71 O Peptidase family M13
LIEFNNIO_01373 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
LIEFNNIO_01374 4.5e-53 K Transcriptional regulator C-terminal region
LIEFNNIO_01376 1.4e-16
LIEFNNIO_01378 6.5e-133 S D5 N terminal like
LIEFNNIO_01379 1.8e-46 L DNA replication protein
LIEFNNIO_01385 3e-07
LIEFNNIO_01386 3.6e-20 K Transcriptional regulator
LIEFNNIO_01388 2e-34 K Helix-turn-helix XRE-family like proteins
LIEFNNIO_01390 2.2e-125 sip L Belongs to the 'phage' integrase family
LIEFNNIO_01391 1.6e-55 jag S R3H domain protein
LIEFNNIO_01392 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
LIEFNNIO_01393 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
LIEFNNIO_01394 5.1e-77 azlC E branched-chain amino acid
LIEFNNIO_01395 1.8e-57 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
LIEFNNIO_01396 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
LIEFNNIO_01397 6.8e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
LIEFNNIO_01398 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
LIEFNNIO_01399 7e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
LIEFNNIO_01400 7.7e-109 endA F DNA RNA non-specific endonuclease
LIEFNNIO_01402 1.2e-207 brnQ U Component of the transport system for branched-chain amino acids
LIEFNNIO_01403 1.7e-61 K Bacterial regulatory proteins, tetR family
LIEFNNIO_01404 1.1e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
LIEFNNIO_01405 7.6e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
LIEFNNIO_01406 3.3e-69 dhaL 2.7.1.121 S Dak2
LIEFNNIO_01407 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
LIEFNNIO_01408 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
LIEFNNIO_01409 3.7e-176 yjcE P Sodium proton antiporter
LIEFNNIO_01410 3.4e-209 mtlR K Mga helix-turn-helix domain
LIEFNNIO_01411 1.1e-301 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LIEFNNIO_01412 4.5e-102 tcyB E ABC transporter
LIEFNNIO_01413 2e-100 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LIEFNNIO_01414 7.5e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
LIEFNNIO_01415 5.5e-39 K Transcriptional regulator
LIEFNNIO_01416 2.2e-107 terC P Integral membrane protein TerC family
LIEFNNIO_01417 3.2e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
LIEFNNIO_01418 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LIEFNNIO_01419 1.4e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
LIEFNNIO_01420 1.1e-41 gntR1 K Transcriptional regulator, GntR family
LIEFNNIO_01421 1.8e-95 V ABC transporter, ATP-binding protein
LIEFNNIO_01422 5.7e-08
LIEFNNIO_01423 1.1e-39 ybjQ S Belongs to the UPF0145 family
LIEFNNIO_01424 1.1e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
LIEFNNIO_01425 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LIEFNNIO_01426 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LIEFNNIO_01427 4.5e-140 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LIEFNNIO_01428 3.7e-34
LIEFNNIO_01429 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LIEFNNIO_01430 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LIEFNNIO_01431 5.2e-63 srtA 3.4.22.70 M sortase family
LIEFNNIO_01433 1.4e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
LIEFNNIO_01434 6.1e-43 yvdD 3.2.2.10 S Possible lysine decarboxylase
LIEFNNIO_01435 0.0 pacL 3.6.3.8 P P-type ATPase
LIEFNNIO_01436 2.4e-109 3.1.4.46 C phosphodiesterase
LIEFNNIO_01437 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LIEFNNIO_01438 8.1e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
LIEFNNIO_01439 9.5e-68 noc K Belongs to the ParB family
LIEFNNIO_01440 5.5e-117 soj D Sporulation initiation inhibitor
LIEFNNIO_01441 9.1e-108 spo0J K Belongs to the ParB family
LIEFNNIO_01442 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
LIEFNNIO_01443 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LIEFNNIO_01444 4.2e-53 XK27_01040 S Protein of unknown function (DUF1129)
LIEFNNIO_01445 7.3e-14 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
LIEFNNIO_01446 1.5e-38
LIEFNNIO_01447 3.9e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
LIEFNNIO_01448 6.5e-98 fhuC P ABC transporter
LIEFNNIO_01449 2.8e-103 znuB U ABC 3 transport family
LIEFNNIO_01450 1.5e-55 S ECF transporter, substrate-specific component
LIEFNNIO_01451 8.8e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LIEFNNIO_01452 2.9e-89 S NADPH-dependent FMN reductase
LIEFNNIO_01453 2.1e-27 yraB K transcriptional regulator
LIEFNNIO_01454 1.5e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
LIEFNNIO_01456 4.5e-154 EGP Major facilitator Superfamily
LIEFNNIO_01457 2.3e-58 S Haloacid dehalogenase-like hydrolase
LIEFNNIO_01458 9.1e-89 yvyE 3.4.13.9 S YigZ family
LIEFNNIO_01459 4.3e-38 S CAAX protease self-immunity
LIEFNNIO_01460 1.5e-117 cps1D M Domain of unknown function (DUF4422)
LIEFNNIO_01461 1.3e-62 S Glycosyltransferase like family 2
LIEFNNIO_01462 2.5e-137 tetA EGP Major facilitator Superfamily
LIEFNNIO_01463 3.9e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
LIEFNNIO_01464 2.1e-213 yjeM E Amino Acid
LIEFNNIO_01465 1.6e-189 glnPH2 P ABC transporter permease
LIEFNNIO_01466 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LIEFNNIO_01467 1.7e-44 E GDSL-like Lipase/Acylhydrolase
LIEFNNIO_01468 3.9e-133 coaA 2.7.1.33 F Pantothenic acid kinase
LIEFNNIO_01469 3.4e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LIEFNNIO_01470 1.1e-50 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
LIEFNNIO_01471 1.8e-49 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
LIEFNNIO_01472 7.2e-38 L hmm pf00665
LIEFNNIO_01473 4.1e-18
LIEFNNIO_01474 8e-112 K IrrE N-terminal-like domain
LIEFNNIO_01475 5e-11
LIEFNNIO_01476 2.8e-37
LIEFNNIO_01477 1.5e-46
LIEFNNIO_01478 6.5e-217 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
LIEFNNIO_01482 5e-125 L T/G mismatch-specific endonuclease activity
LIEFNNIO_01484 6.6e-60 hsdM 2.1.1.72 V type I restriction-modification system
LIEFNNIO_01485 5.6e-18 3.1.21.3 V Type I restriction modification DNA specificity domain
LIEFNNIO_01486 2.6e-105 L Belongs to the 'phage' integrase family
LIEFNNIO_01487 7.1e-15 L Plasmid pRiA4b ORF-3-like protein
LIEFNNIO_01488 4.9e-190 XK27_11280 S Psort location CytoplasmicMembrane, score
LIEFNNIO_01489 5.4e-58 S COG NOG19168 non supervised orthologous group
LIEFNNIO_01491 2.3e-104 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
LIEFNNIO_01493 1.2e-216 pts36C G PTS system sugar-specific permease component
LIEFNNIO_01494 6.9e-42 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
LIEFNNIO_01495 1.1e-46 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LIEFNNIO_01496 2.2e-70 K DeoR C terminal sensor domain
LIEFNNIO_01497 1.7e-122 yvgN C Aldo keto reductase
LIEFNNIO_01498 3.3e-123 yvgN C Aldo keto reductase
LIEFNNIO_01504 1.3e-16 M domain protein
LIEFNNIO_01506 1.6e-22 agrA KT Response regulator of the LytR AlgR family
LIEFNNIO_01507 1.8e-43 2.7.13.3 T protein histidine kinase activity
LIEFNNIO_01508 0.0 pepN 3.4.11.2 E aminopeptidase
LIEFNNIO_01509 1.1e-35
LIEFNNIO_01511 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
LIEFNNIO_01512 1.4e-12 bglG K antiterminator
LIEFNNIO_01513 1.4e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LIEFNNIO_01514 8.5e-141 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LIEFNNIO_01515 1.9e-37 S Replication initiator protein A (RepA) N-terminus
LIEFNNIO_01516 9.4e-109 L Initiator Replication protein
LIEFNNIO_01517 6.1e-08 yokH G regulation of fungal-type cell wall biogenesis
LIEFNNIO_01519 6.5e-12 L PLD-like domain
LIEFNNIO_01520 3.5e-23 L PLD-like domain
LIEFNNIO_01521 4.7e-73 L HTH-like domain
LIEFNNIO_01522 2.6e-30 L Helix-turn-helix domain
LIEFNNIO_01523 1.8e-106 L PLD-like domain
LIEFNNIO_01525 1.1e-09 tcdC
LIEFNNIO_01527 3.1e-233 tetP J elongation factor G
LIEFNNIO_01528 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LIEFNNIO_01530 4.5e-216 yjeM E Amino Acid
LIEFNNIO_01531 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
LIEFNNIO_01532 4.3e-75 K Helix-turn-helix domain, rpiR family
LIEFNNIO_01533 2.5e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LIEFNNIO_01534 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
LIEFNNIO_01535 6.5e-90 nanK GK ROK family
LIEFNNIO_01536 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
LIEFNNIO_01537 4e-64 G Xylose isomerase domain protein TIM barrel
LIEFNNIO_01538 9.6e-153 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LIEFNNIO_01539 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LIEFNNIO_01540 1.1e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
LIEFNNIO_01541 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LIEFNNIO_01542 7.7e-41 S Iron-sulfur cluster assembly protein
LIEFNNIO_01543 1.3e-66 S Protein of unknown function (DUF1440)
LIEFNNIO_01544 1.7e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
LIEFNNIO_01545 5.9e-187 mtnE 2.6.1.83 E Aminotransferase
LIEFNNIO_01547 2.7e-15
LIEFNNIO_01548 1e-87 S Haloacid dehalogenase-like hydrolase
LIEFNNIO_01551 2.9e-71 xerD L Phage integrase, N-terminal SAM-like domain
LIEFNNIO_01552 9.1e-265 fbp 3.1.3.11 G phosphatase activity
LIEFNNIO_01554 9.2e-32 tonB M YSIRK type signal peptide
LIEFNNIO_01557 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LIEFNNIO_01558 3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
LIEFNNIO_01559 1.1e-21 S Phage minor capsid protein 2
LIEFNNIO_01567 1.7e-52 M Phage tail tape measure protein TP901
LIEFNNIO_01568 1e-26 M by MetaGeneAnnotator
LIEFNNIO_01569 5.2e-110 IQ NAD dependent epimerase/dehydratase family
LIEFNNIO_01570 1.7e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
LIEFNNIO_01571 4.5e-43 gutM K Glucitol operon activator protein (GutM)
LIEFNNIO_01572 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
LIEFNNIO_01573 2.7e-135 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
LIEFNNIO_01574 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
LIEFNNIO_01575 2.8e-64 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
LIEFNNIO_01576 2.5e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
LIEFNNIO_01577 7.3e-136 pfoS S Phosphotransferase system, EIIC
LIEFNNIO_01578 1.6e-26 K Helix-turn-helix XRE-family like proteins
LIEFNNIO_01579 5.3e-24 S protein encoded in hypervariable junctions of pilus gene clusters
LIEFNNIO_01580 1.4e-223 E ABC transporter, substratebinding protein
LIEFNNIO_01581 4e-115 sufC O FeS assembly ATPase SufC
LIEFNNIO_01582 1.1e-143 sufD O FeS assembly protein SufD
LIEFNNIO_01583 3.1e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LIEFNNIO_01584 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
LIEFNNIO_01585 9.4e-240 sufB O assembly protein SufB
LIEFNNIO_01586 7.2e-45 S VIT family
LIEFNNIO_01587 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
LIEFNNIO_01588 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LIEFNNIO_01589 4.7e-112 rssA S Phospholipase, patatin family
LIEFNNIO_01590 8.2e-16
LIEFNNIO_01591 2.7e-30
LIEFNNIO_01592 1.7e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LIEFNNIO_01593 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LIEFNNIO_01594 5.2e-79 yvfR V ABC transporter
LIEFNNIO_01595 1.2e-52 yvfS V ABC-2 type transporter
LIEFNNIO_01596 1.2e-56 salK 2.7.13.3 T Histidine kinase
LIEFNNIO_01597 2.4e-75 desR K helix_turn_helix, Lux Regulon
LIEFNNIO_01598 6.4e-29 ptp3 3.1.3.48 T Tyrosine phosphatase family
LIEFNNIO_01599 8.2e-13 ptp3 3.1.3.48 T Tyrosine phosphatase family
LIEFNNIO_01600 3.4e-103 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
LIEFNNIO_01605 1.4e-32 S Domain of unknown function (DUF4417)
LIEFNNIO_01606 1.1e-142 xerS L Phage integrase family
LIEFNNIO_01607 2e-71 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LIEFNNIO_01608 6.5e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LIEFNNIO_01609 1.6e-217 1.3.5.4 C FAD binding domain
LIEFNNIO_01610 5e-116 IQ Enoyl-(Acyl carrier protein) reductase
LIEFNNIO_01611 4.7e-138 G Xylose isomerase-like TIM barrel
LIEFNNIO_01612 3.7e-72 K Transcriptional regulator, LysR family
LIEFNNIO_01613 4.1e-98 EGP Major Facilitator Superfamily
LIEFNNIO_01614 2.6e-129 EGP Major Facilitator Superfamily
LIEFNNIO_01615 2.4e-35 L Integrase core domain
LIEFNNIO_01616 1.4e-41 L Integrase core domain
LIEFNNIO_01617 1.3e-20 L PFAM transposase IS3 IS911 family protein
LIEFNNIO_01618 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
LIEFNNIO_01619 1.7e-32 P Heavy-metal-associated domain
LIEFNNIO_01620 8.7e-31 tnp L Transposase IS66 family
LIEFNNIO_01621 5e-18 tnp
LIEFNNIO_01622 9.6e-44 L hmm pf00665
LIEFNNIO_01623 1.1e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
LIEFNNIO_01624 4.6e-84 dps P Ferritin-like domain
LIEFNNIO_01625 1.1e-157 L transposase, IS605 OrfB family
LIEFNNIO_01626 2.5e-58 tlpA2 L Transposase IS200 like
LIEFNNIO_01627 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
LIEFNNIO_01628 0.0 O Belongs to the peptidase S8 family
LIEFNNIO_01629 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LIEFNNIO_01630 1.8e-116 O AAA domain (Cdc48 subfamily)
LIEFNNIO_01631 4.1e-67
LIEFNNIO_01632 8.6e-90 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
LIEFNNIO_01633 4e-225 hsdM 2.1.1.72 V type I restriction-modification system
LIEFNNIO_01634 9.1e-286 hsdR 3.1.21.3 L DEAD/DEAH box helicase
LIEFNNIO_01635 3.4e-07
LIEFNNIO_01636 4.2e-45 yjaB_1 K Acetyltransferase (GNAT) domain
LIEFNNIO_01637 3.5e-80 yitS S EDD domain protein, DegV family
LIEFNNIO_01638 1.9e-57 racA K Domain of unknown function (DUF1836)
LIEFNNIO_01639 2.7e-116 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LIEFNNIO_01640 1.1e-145 ald 1.4.1.1 C Belongs to the AlaDH PNT family
LIEFNNIO_01641 1.3e-161 potE2 E amino acid
LIEFNNIO_01644 4.6e-24
LIEFNNIO_01646 4.6e-15
LIEFNNIO_01647 1.5e-92 pstS P T5orf172
LIEFNNIO_01648 2.4e-257 yeeB L DEAD-like helicases superfamily
LIEFNNIO_01649 6.9e-206 yeeA V Type II restriction enzyme, methylase subunits
LIEFNNIO_01650 3.2e-95 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
LIEFNNIO_01652 6.3e-54 S Protein of unknown function (DUF4256)
LIEFNNIO_01653 8.2e-127 metQ M Belongs to the nlpA lipoprotein family
LIEFNNIO_01654 2.4e-31 metI U ABC transporter permease
LIEFNNIO_01655 6.2e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LIEFNNIO_01657 1e-261 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
LIEFNNIO_01658 8.1e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LIEFNNIO_01659 1e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
LIEFNNIO_01660 4.3e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
LIEFNNIO_01661 3e-84 drgA C nitroreductase
LIEFNNIO_01662 8.2e-133 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
LIEFNNIO_01663 1.3e-69 metI P ABC transporter permease
LIEFNNIO_01664 2.6e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LIEFNNIO_01665 1.8e-108 metQ1 P Belongs to the nlpA lipoprotein family
LIEFNNIO_01666 2e-144 2.1.1.14 E methionine synthase, vitamin-B12 independent
LIEFNNIO_01667 1e-45 yphJ 4.1.1.44 S decarboxylase
LIEFNNIO_01668 1.4e-58 yphH S Cupin domain
LIEFNNIO_01669 5.7e-48 C Flavodoxin
LIEFNNIO_01670 2.7e-56 S CAAX protease self-immunity
LIEFNNIO_01671 1.5e-102 pgm3 G phosphoglycerate mutase
LIEFNNIO_01672 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LIEFNNIO_01673 4.2e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LIEFNNIO_01674 1.4e-49 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LIEFNNIO_01675 4.4e-67 M ErfK YbiS YcfS YnhG
LIEFNNIO_01676 3.9e-107 XK27_08845 S ABC transporter, ATP-binding protein
LIEFNNIO_01677 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
LIEFNNIO_01678 5.1e-131 ABC-SBP S ABC transporter
LIEFNNIO_01679 1.7e-159 potD P ABC transporter
LIEFNNIO_01680 1.7e-103 potC U Binding-protein-dependent transport system inner membrane component
LIEFNNIO_01681 1.5e-120 potB P ABC transporter permease
LIEFNNIO_01682 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LIEFNNIO_01683 2.4e-98 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
LIEFNNIO_01684 2.2e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
LIEFNNIO_01685 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LIEFNNIO_01686 3.9e-13 S Enterocin A Immunity
LIEFNNIO_01688 2.2e-16 pspC KT PspC domain
LIEFNNIO_01689 4.1e-16 S Putative adhesin
LIEFNNIO_01690 4.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
LIEFNNIO_01691 1.3e-38 K transcriptional regulator PadR family
LIEFNNIO_01692 1.5e-46 S CRISPR-associated protein (Cas_Csn2)
LIEFNNIO_01693 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LIEFNNIO_01694 7.2e-108 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LIEFNNIO_01695 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LIEFNNIO_01696 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
LIEFNNIO_01697 3.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
LIEFNNIO_01698 4.9e-165 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LIEFNNIO_01699 1.4e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LIEFNNIO_01700 2.7e-70 mltD CBM50 M NlpC P60 family protein
LIEFNNIO_01701 3.2e-52 manO S Domain of unknown function (DUF956)
LIEFNNIO_01702 2.1e-147 manN G system, mannose fructose sorbose family IID component
LIEFNNIO_01703 6.4e-116 manY G PTS system sorbose-specific iic component
LIEFNNIO_01704 5.3e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
LIEFNNIO_01705 2.6e-79 rbsB G sugar-binding domain protein
LIEFNNIO_01706 1.2e-103 baeS T Histidine kinase
LIEFNNIO_01707 3e-79 baeR K Bacterial regulatory proteins, luxR family
LIEFNNIO_01708 2.6e-119 G Bacterial extracellular solute-binding protein
LIEFNNIO_01709 2.3e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LIEFNNIO_01710 4.2e-32 merR K MerR HTH family regulatory protein
LIEFNNIO_01711 7.9e-197 lmrB EGP Major facilitator Superfamily
LIEFNNIO_01712 1.3e-32 S Domain of unknown function (DUF4811)
LIEFNNIO_01713 8.2e-84 G Phosphoglycerate mutase family
LIEFNNIO_01714 5e-60 yceE S haloacid dehalogenase-like hydrolase
LIEFNNIO_01715 8.4e-73 glcR K DeoR C terminal sensor domain
LIEFNNIO_01716 2.4e-93 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LIEFNNIO_01717 1.1e-182 lmrB EGP Major facilitator Superfamily
LIEFNNIO_01718 5.6e-282 fruA 3.2.1.1, 3.2.1.65, 3.2.1.80 GH13,GH32 GN Fructan beta-fructosidase
LIEFNNIO_01719 3.3e-52 bioY S BioY family
LIEFNNIO_01720 9.9e-93 S Predicted membrane protein (DUF2207)
LIEFNNIO_01721 1.4e-19
LIEFNNIO_01722 4e-38 M Glycosyltransferase like family 2
LIEFNNIO_01723 9.8e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
LIEFNNIO_01724 9.7e-59 ktrA P TrkA-N domain
LIEFNNIO_01725 1.2e-114 ntpJ P Potassium uptake protein
LIEFNNIO_01726 7.7e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
LIEFNNIO_01727 5.2e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
LIEFNNIO_01728 1.2e-216 scrB 3.2.1.26 GH32 G invertase
LIEFNNIO_01729 2.3e-147 scrR K helix_turn _helix lactose operon repressor
LIEFNNIO_01730 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LIEFNNIO_01731 4.7e-210 glnP P ABC transporter
LIEFNNIO_01733 1.1e-59 uspA T Universal stress protein family
LIEFNNIO_01734 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
LIEFNNIO_01735 1.1e-25
LIEFNNIO_01736 1.4e-200 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
LIEFNNIO_01737 8e-110 puuD S peptidase C26
LIEFNNIO_01738 1.4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LIEFNNIO_01739 3.3e-150 lsa S ABC transporter
LIEFNNIO_01740 9.4e-149 mepA V MATE efflux family protein
LIEFNNIO_01741 5.2e-87 L PFAM Integrase catalytic region
LIEFNNIO_01743 7.8e-136 S interspecies interaction between organisms
LIEFNNIO_01744 1.2e-207 G glycerol-3-phosphate transporter
LIEFNNIO_01745 5.8e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LIEFNNIO_01746 6.2e-145 htrA 3.4.21.107 O serine protease
LIEFNNIO_01747 2.2e-116 vicX 3.1.26.11 S domain protein
LIEFNNIO_01748 6.8e-30 yyaQ S YjbR
LIEFNNIO_01749 5.6e-80 yycI S YycH protein
LIEFNNIO_01750 7.9e-103 yycH S YycH protein
LIEFNNIO_01751 1.5e-272 vicK 2.7.13.3 T Histidine kinase
LIEFNNIO_01752 9e-114 K response regulator
LIEFNNIO_01753 6.1e-106 yxeH S hydrolase
LIEFNNIO_01754 1e-227 V ABC transporter transmembrane region
LIEFNNIO_01755 1.1e-216 XK27_09600 V ABC transporter, ATP-binding protein
LIEFNNIO_01756 7.1e-32 K Transcriptional regulator, MarR family
LIEFNNIO_01757 8.9e-174 S Putative peptidoglycan binding domain
LIEFNNIO_01758 3.8e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LIEFNNIO_01759 1.1e-137 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
LIEFNNIO_01760 1.5e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LIEFNNIO_01761 3.1e-106 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LIEFNNIO_01762 4.5e-204 pepF E Oligopeptidase F
LIEFNNIO_01763 4.9e-96 yicL EG EamA-like transporter family
LIEFNNIO_01764 7e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
LIEFNNIO_01765 1.6e-167 yjjP S Putative threonine/serine exporter
LIEFNNIO_01766 1.7e-24 S PFAM Archaeal ATPase
LIEFNNIO_01767 3e-60 S PFAM Archaeal ATPase
LIEFNNIO_01768 2.7e-170 ydfJ EGP Sugar (and other) transporter
LIEFNNIO_01769 1.3e-137 rspB 1.1.1.380 C Zinc-binding dehydrogenase
LIEFNNIO_01770 1.5e-173 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
LIEFNNIO_01771 5.5e-207 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
LIEFNNIO_01772 1.5e-49 kdgR K FCD domain
LIEFNNIO_01773 1e-113 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
LIEFNNIO_01774 3.7e-61 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
LIEFNNIO_01775 4.8e-109 glcU U sugar transport
LIEFNNIO_01776 1e-14 yobS K transcriptional regulator
LIEFNNIO_01777 2e-153 mdtG EGP Major facilitator Superfamily
LIEFNNIO_01778 1.2e-105 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LIEFNNIO_01779 4.2e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
LIEFNNIO_01780 7.4e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LIEFNNIO_01781 9.5e-18 yneR
LIEFNNIO_01782 4.8e-247 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LIEFNNIO_01783 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LIEFNNIO_01784 2.1e-60 yiiE S Protein of unknown function (DUF1211)
LIEFNNIO_01785 0.0 asnB 6.3.5.4 E Asparagine synthase
LIEFNNIO_01786 7.4e-64 D peptidase
LIEFNNIO_01787 7.3e-117 S Glycosyl transferase family 2
LIEFNNIO_01788 4.8e-109 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
LIEFNNIO_01789 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LIEFNNIO_01790 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LIEFNNIO_01791 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
LIEFNNIO_01792 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LIEFNNIO_01793 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LIEFNNIO_01794 1.2e-152 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LIEFNNIO_01795 9e-20 yaaA S S4 domain protein YaaA
LIEFNNIO_01796 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LIEFNNIO_01797 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LIEFNNIO_01798 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
LIEFNNIO_01799 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LIEFNNIO_01800 3.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LIEFNNIO_01801 1.1e-199 nupG F Nucleoside
LIEFNNIO_01802 1.3e-121 MA20_14895 S Conserved hypothetical protein 698
LIEFNNIO_01803 1.7e-53 K LysR substrate binding domain
LIEFNNIO_01804 9.6e-09
LIEFNNIO_01805 3.2e-67 yxkH G Polysaccharide deacetylase
LIEFNNIO_01806 9e-30 yqkB S Belongs to the HesB IscA family
LIEFNNIO_01808 3.8e-146 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LIEFNNIO_01809 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LIEFNNIO_01810 1.1e-278 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LIEFNNIO_01811 3.5e-160 camS S sex pheromone
LIEFNNIO_01812 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LIEFNNIO_01813 1.8e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LIEFNNIO_01814 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LIEFNNIO_01815 3.4e-146 yegS 2.7.1.107 G Lipid kinase
LIEFNNIO_01816 1.8e-211 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LIEFNNIO_01817 2.4e-82
LIEFNNIO_01818 2.6e-44 yjdF S Protein of unknown function (DUF2992)
LIEFNNIO_01820 5.5e-196 L Recombinase
LIEFNNIO_01821 7.1e-15 S Recombinase
LIEFNNIO_01822 1.9e-116 L Recombinase zinc beta ribbon domain
LIEFNNIO_01824 2.9e-51 S Bacteriophage holin family
LIEFNNIO_01825 5.6e-46 S Phage head-tail joining protein
LIEFNNIO_01826 7.1e-30 S Phage gp6-like head-tail connector protein
LIEFNNIO_01827 6.6e-170 S Phage capsid family
LIEFNNIO_01828 3.2e-81 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
LIEFNNIO_01829 2.6e-217 S Phage portal protein
LIEFNNIO_01830 2.8e-11 K Antidote-toxin recognition MazE, bacterial antitoxin
LIEFNNIO_01832 2.5e-289 S overlaps another CDS with the same product name
LIEFNNIO_01833 1.1e-24 S Domain of unknown function (DUF5049)
LIEFNNIO_01834 2.7e-53 S Psort location Cytoplasmic, score
LIEFNNIO_01835 2.9e-200 2.1.1.72 KL DNA methylase
LIEFNNIO_01836 5.7e-92
LIEFNNIO_01837 4.6e-56 V HNH nucleases
LIEFNNIO_01838 2.1e-50
LIEFNNIO_01839 6.7e-198 L SNF2 family N-terminal domain
LIEFNNIO_01840 2.8e-32 S VRR_NUC
LIEFNNIO_01841 0.0 S Phage plasmid primase, P4
LIEFNNIO_01842 1.1e-39 S Psort location Cytoplasmic, score
LIEFNNIO_01843 1e-300 polA_2 2.7.7.7 L DNA polymerase
LIEFNNIO_01844 5e-88 S Protein of unknown function (DUF2815)
LIEFNNIO_01845 5.3e-143 L Protein of unknown function (DUF2800)
LIEFNNIO_01847 1.9e-08
LIEFNNIO_01849 2.9e-25
LIEFNNIO_01850 3.5e-15
LIEFNNIO_01851 2.9e-76 L AAA domain
LIEFNNIO_01852 4.8e-20 K Cro/C1-type HTH DNA-binding domain
LIEFNNIO_01853 1.7e-86 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
LIEFNNIO_01854 1.3e-113 2.1.1.72, 3.1.21.4 L site-specific DNA-methyltransferase (adenine-specific) activity
LIEFNNIO_01855 0.0 L Type III restriction enzyme, res subunit
LIEFNNIO_01856 0.0 S Protein of unknown function DUF262
LIEFNNIO_01859 1.2e-52 L Resolvase, N terminal domain
LIEFNNIO_01860 2.1e-48 L COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
LIEFNNIO_01861 0.0 3.1.11.5 L Psort location Cytoplasmic, score 8.87
LIEFNNIO_01862 5.1e-24
LIEFNNIO_01863 4.4e-34 3.1.21.3 V Type I restriction modification DNA specificity domain
LIEFNNIO_01865 2.6e-56 S UPF0489 domain
LIEFNNIO_01866 1.9e-121 L Mrr N-terminal domain
LIEFNNIO_01867 1.6e-14
LIEFNNIO_01868 1.7e-08
LIEFNNIO_01869 3.2e-74 S Domain of unknown function (DUF4343)
LIEFNNIO_01870 1.5e-57 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
LIEFNNIO_01871 1.2e-74 S Domain of unknown function (DUF3841)
LIEFNNIO_01872 8.1e-228 yfjM S Protein of unknown function DUF262
LIEFNNIO_01873 6.6e-176 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
LIEFNNIO_01874 2.8e-157 C Oxidoreductase
LIEFNNIO_01875 1.1e-71 ywlG S Belongs to the UPF0340 family
LIEFNNIO_01876 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
LIEFNNIO_01877 1.6e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LIEFNNIO_01878 1.5e-57 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LIEFNNIO_01879 8.2e-177 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
LIEFNNIO_01880 1.5e-14 ybaN S Protein of unknown function (DUF454)
LIEFNNIO_01881 1.3e-236 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LIEFNNIO_01882 1.4e-198 frdC 1.3.5.4 C FAD binding domain
LIEFNNIO_01883 1.1e-206 yflS P Sodium:sulfate symporter transmembrane region
LIEFNNIO_01884 4.4e-18 yncA 2.3.1.79 S Maltose acetyltransferase
LIEFNNIO_01885 8.2e-160 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LIEFNNIO_01886 1.5e-61 dedA 3.1.3.1 S SNARE associated Golgi protein
LIEFNNIO_01887 2.7e-94 ypuA S Protein of unknown function (DUF1002)
LIEFNNIO_01888 3.2e-92 yihY S Belongs to the UPF0761 family
LIEFNNIO_01889 6.2e-12 mltD CBM50 M Lysin motif
LIEFNNIO_01890 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LIEFNNIO_01891 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
LIEFNNIO_01892 2.6e-53 fld C Flavodoxin
LIEFNNIO_01893 8.7e-53 gtcA S Teichoic acid glycosylation protein
LIEFNNIO_01894 0.0 S Bacterial membrane protein YfhO
LIEFNNIO_01895 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
LIEFNNIO_01896 6.4e-122 S Sulfite exporter TauE/SafE
LIEFNNIO_01897 1.1e-70 K Sugar-specific transcriptional regulator TrmB
LIEFNNIO_01898 2.1e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LIEFNNIO_01899 1.3e-181 pepS E Thermophilic metalloprotease (M29)
LIEFNNIO_01900 2.2e-264 E Amino acid permease
LIEFNNIO_01901 7.8e-83 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
LIEFNNIO_01902 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
LIEFNNIO_01903 7.7e-79 galM 5.1.3.3 G Aldose 1-epimerase
LIEFNNIO_01904 3.8e-214 malT G Transporter, major facilitator family protein
LIEFNNIO_01905 1.2e-100 malR K Transcriptional regulator, LacI family
LIEFNNIO_01906 1.3e-279 kup P Transport of potassium into the cell
LIEFNNIO_01908 2e-20 S Domain of unknown function (DUF3284)
LIEFNNIO_01909 3.9e-160 yfmL L DEAD DEAH box helicase
LIEFNNIO_01910 5.4e-128 mocA S Oxidoreductase
LIEFNNIO_01911 3.4e-24 S Domain of unknown function (DUF4828)
LIEFNNIO_01912 1.5e-176 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
LIEFNNIO_01913 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LIEFNNIO_01914 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
LIEFNNIO_01915 4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
LIEFNNIO_01916 1.1e-156 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LIEFNNIO_01917 6.2e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LIEFNNIO_01918 4.2e-221 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
LIEFNNIO_01919 2.2e-42 O ADP-ribosylglycohydrolase
LIEFNNIO_01920 4.6e-220 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
LIEFNNIO_01921 3.8e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
LIEFNNIO_01922 2e-16 XK27_09675 K Acetyltransferase (GNAT) domain
LIEFNNIO_01923 1.7e-40
LIEFNNIO_01925 9.4e-160 mgtE P Acts as a magnesium transporter
LIEFNNIO_01926 7.6e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
LIEFNNIO_01927 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LIEFNNIO_01928 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
LIEFNNIO_01929 9e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
LIEFNNIO_01930 3e-37 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
LIEFNNIO_01931 1.7e-193 pbuX F xanthine permease
LIEFNNIO_01932 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LIEFNNIO_01933 1.6e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
LIEFNNIO_01934 1.6e-63 S ECF transporter, substrate-specific component
LIEFNNIO_01935 1.6e-13 mleP S Sodium Bile acid symporter family
LIEFNNIO_01936 5.8e-249 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
LIEFNNIO_01937 2.4e-71 mleR K LysR family
LIEFNNIO_01938 3.6e-57 K transcriptional
LIEFNNIO_01939 1.3e-40 K Bacterial regulatory proteins, tetR family
LIEFNNIO_01940 8e-60 T Belongs to the universal stress protein A family
LIEFNNIO_01941 1.5e-42 K Copper transport repressor CopY TcrY
LIEFNNIO_01942 3.4e-07 fhaB M translation initiation factor activity

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)