ORF_ID e_value Gene_name EC_number CAZy COGs Description
EPJLBGNC_00006 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EPJLBGNC_00007 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EPJLBGNC_00008 2.4e-192 cycA E Amino acid permease
EPJLBGNC_00009 6.4e-187 ytgP S Polysaccharide biosynthesis protein
EPJLBGNC_00010 5.2e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EPJLBGNC_00011 1.2e-80 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EPJLBGNC_00012 3e-193 pepV 3.5.1.18 E dipeptidase PepV
EPJLBGNC_00014 5.2e-36
EPJLBGNC_00015 3.4e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EPJLBGNC_00016 4.2e-61 marR K Transcriptional regulator, MarR family
EPJLBGNC_00017 2.9e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPJLBGNC_00018 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPJLBGNC_00019 2.9e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EPJLBGNC_00020 2.5e-98 IQ reductase
EPJLBGNC_00021 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EPJLBGNC_00022 4.6e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EPJLBGNC_00023 3.9e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EPJLBGNC_00024 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
EPJLBGNC_00025 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EPJLBGNC_00026 4.4e-101 accA 2.1.3.15, 6.4.1.2 I alpha subunit
EPJLBGNC_00027 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
EPJLBGNC_00028 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EPJLBGNC_00029 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
EPJLBGNC_00030 1.3e-301 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EPJLBGNC_00031 5.7e-119 gla U Major intrinsic protein
EPJLBGNC_00032 5.8e-45 ykuL S CBS domain
EPJLBGNC_00033 3.9e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EPJLBGNC_00034 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EPJLBGNC_00035 9e-87 ykuT M mechanosensitive ion channel
EPJLBGNC_00037 3e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EPJLBGNC_00038 2e-21 yheA S Belongs to the UPF0342 family
EPJLBGNC_00039 8.6e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
EPJLBGNC_00040 3.3e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EPJLBGNC_00042 7e-53 hit FG histidine triad
EPJLBGNC_00043 1.3e-94 ecsA V ABC transporter, ATP-binding protein
EPJLBGNC_00044 6.4e-72 ecsB U ABC transporter
EPJLBGNC_00045 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
EPJLBGNC_00046 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EPJLBGNC_00048 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EPJLBGNC_00049 4e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EPJLBGNC_00050 1.2e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
EPJLBGNC_00051 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EPJLBGNC_00052 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
EPJLBGNC_00053 6.7e-69 ybhL S Belongs to the BI1 family
EPJLBGNC_00054 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPJLBGNC_00055 4.3e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EPJLBGNC_00056 1.6e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EPJLBGNC_00057 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EPJLBGNC_00058 1.4e-78 dnaB L replication initiation and membrane attachment
EPJLBGNC_00059 1.3e-107 dnaI L Primosomal protein DnaI
EPJLBGNC_00060 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EPJLBGNC_00061 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EPJLBGNC_00062 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EPJLBGNC_00063 2.2e-52 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EPJLBGNC_00064 1.2e-70 yqeG S HAD phosphatase, family IIIA
EPJLBGNC_00065 1.9e-179 yqeH S Ribosome biogenesis GTPase YqeH
EPJLBGNC_00066 6e-30 yhbY J RNA-binding protein
EPJLBGNC_00067 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EPJLBGNC_00068 2.6e-69 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
EPJLBGNC_00069 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EPJLBGNC_00070 1.5e-82 H Nodulation protein S (NodS)
EPJLBGNC_00071 1e-122 ylbM S Belongs to the UPF0348 family
EPJLBGNC_00072 2e-57 yceD S Uncharacterized ACR, COG1399
EPJLBGNC_00073 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EPJLBGNC_00074 4e-89 plsC 2.3.1.51 I Acyltransferase
EPJLBGNC_00075 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
EPJLBGNC_00076 1.5e-27 yazA L GIY-YIG catalytic domain protein
EPJLBGNC_00077 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
EPJLBGNC_00078 7.9e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EPJLBGNC_00079 6.9e-37
EPJLBGNC_00080 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
EPJLBGNC_00081 1.4e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EPJLBGNC_00082 7.1e-158 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EPJLBGNC_00083 3.5e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EPJLBGNC_00084 6.6e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EPJLBGNC_00086 3.1e-111 K response regulator
EPJLBGNC_00087 3.9e-167 arlS 2.7.13.3 T Histidine kinase
EPJLBGNC_00088 1.8e-117 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EPJLBGNC_00089 1.6e-23 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EPJLBGNC_00090 4.7e-136 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
EPJLBGNC_00091 7.3e-105
EPJLBGNC_00092 5.5e-117
EPJLBGNC_00093 1.3e-41 dut S dUTPase
EPJLBGNC_00094 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EPJLBGNC_00095 1.8e-45 yqhY S Asp23 family, cell envelope-related function
EPJLBGNC_00096 5.5e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EPJLBGNC_00097 1e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EPJLBGNC_00098 2.9e-145 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPJLBGNC_00099 9.6e-17 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPJLBGNC_00100 1.6e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EPJLBGNC_00101 5.7e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EPJLBGNC_00102 6.6e-49 argR K Regulates arginine biosynthesis genes
EPJLBGNC_00103 8.7e-176 recN L May be involved in recombinational repair of damaged DNA
EPJLBGNC_00104 2.5e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EPJLBGNC_00105 2.2e-30 ynzC S UPF0291 protein
EPJLBGNC_00106 2.9e-26 yneF S UPF0154 protein
EPJLBGNC_00107 1.6e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
EPJLBGNC_00108 2.1e-43 MA20_27270 S mazG nucleotide pyrophosphohydrolase
EPJLBGNC_00109 2.5e-75 yciQ P membrane protein (DUF2207)
EPJLBGNC_00110 1.3e-19 D nuclear chromosome segregation
EPJLBGNC_00111 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EPJLBGNC_00112 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EPJLBGNC_00113 2.4e-68 gluP 3.4.21.105 S Peptidase, S54 family
EPJLBGNC_00114 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
EPJLBGNC_00115 6.2e-158 glk 2.7.1.2 G Glucokinase
EPJLBGNC_00116 2.7e-46 yqhL P Rhodanese-like protein
EPJLBGNC_00117 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
EPJLBGNC_00118 2.7e-110 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EPJLBGNC_00119 3.6e-206 ynbB 4.4.1.1 P aluminum resistance
EPJLBGNC_00120 1.3e-45 glnR K Transcriptional regulator
EPJLBGNC_00121 2e-247 glnA 6.3.1.2 E glutamine synthetase
EPJLBGNC_00123 4.4e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EPJLBGNC_00124 2.7e-48 S Domain of unknown function (DUF956)
EPJLBGNC_00125 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EPJLBGNC_00126 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EPJLBGNC_00127 1.7e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EPJLBGNC_00128 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
EPJLBGNC_00129 5.3e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EPJLBGNC_00130 1e-259 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EPJLBGNC_00131 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPJLBGNC_00132 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
EPJLBGNC_00133 3.7e-170 nusA K Participates in both transcription termination and antitermination
EPJLBGNC_00134 1.2e-38 ylxR K Protein of unknown function (DUF448)
EPJLBGNC_00135 3.4e-25 ylxQ J ribosomal protein
EPJLBGNC_00136 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EPJLBGNC_00137 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EPJLBGNC_00138 3.1e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EPJLBGNC_00139 1.6e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EPJLBGNC_00140 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EPJLBGNC_00141 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EPJLBGNC_00142 1.5e-274 dnaK O Heat shock 70 kDa protein
EPJLBGNC_00143 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EPJLBGNC_00144 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EPJLBGNC_00146 4.6e-205 glnP P ABC transporter
EPJLBGNC_00147 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EPJLBGNC_00148 1.5e-31
EPJLBGNC_00149 2e-111 ampC V Beta-lactamase
EPJLBGNC_00150 3.5e-110 cobQ S glutamine amidotransferase
EPJLBGNC_00151 3e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
EPJLBGNC_00152 2.6e-85 tdk 2.7.1.21 F thymidine kinase
EPJLBGNC_00153 1.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EPJLBGNC_00154 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EPJLBGNC_00155 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EPJLBGNC_00156 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EPJLBGNC_00157 2.6e-97 atpB C it plays a direct role in the translocation of protons across the membrane
EPJLBGNC_00158 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPJLBGNC_00159 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EPJLBGNC_00160 7e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPJLBGNC_00161 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EPJLBGNC_00162 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EPJLBGNC_00163 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EPJLBGNC_00164 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EPJLBGNC_00165 4.1e-15 ywzB S Protein of unknown function (DUF1146)
EPJLBGNC_00166 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPJLBGNC_00167 1.3e-166 mbl D Cell shape determining protein MreB Mrl
EPJLBGNC_00168 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EPJLBGNC_00169 1.3e-13 S Protein of unknown function (DUF2969)
EPJLBGNC_00170 1e-186 rodA D Belongs to the SEDS family
EPJLBGNC_00171 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
EPJLBGNC_00172 1.9e-94 2.7.1.89 M Phosphotransferase enzyme family
EPJLBGNC_00173 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EPJLBGNC_00174 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EPJLBGNC_00175 7.5e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EPJLBGNC_00176 9.2e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EPJLBGNC_00177 1.5e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EPJLBGNC_00178 2e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EPJLBGNC_00179 1.9e-90 stp 3.1.3.16 T phosphatase
EPJLBGNC_00180 1.8e-192 KLT serine threonine protein kinase
EPJLBGNC_00181 8.4e-109 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EPJLBGNC_00182 3.5e-59 thiN 2.7.6.2 H thiamine pyrophosphokinase
EPJLBGNC_00183 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EPJLBGNC_00184 4.5e-53 asp S Asp23 family, cell envelope-related function
EPJLBGNC_00185 1.3e-238 yloV S DAK2 domain fusion protein YloV
EPJLBGNC_00186 2.2e-245 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EPJLBGNC_00187 1.8e-139 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EPJLBGNC_00188 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPJLBGNC_00189 3.9e-101 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EPJLBGNC_00190 1.8e-210 smc D Required for chromosome condensation and partitioning
EPJLBGNC_00191 5.5e-146 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EPJLBGNC_00192 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EPJLBGNC_00193 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EPJLBGNC_00194 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EPJLBGNC_00195 1.1e-26 ylqC S Belongs to the UPF0109 family
EPJLBGNC_00196 2.5e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EPJLBGNC_00197 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EPJLBGNC_00198 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
EPJLBGNC_00199 3.7e-199 yfnA E amino acid
EPJLBGNC_00200 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EPJLBGNC_00201 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
EPJLBGNC_00202 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EPJLBGNC_00203 6.9e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EPJLBGNC_00204 3.2e-266 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPJLBGNC_00205 1.6e-22 S Tetratricopeptide repeat
EPJLBGNC_00206 8e-216 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EPJLBGNC_00207 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EPJLBGNC_00208 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EPJLBGNC_00209 9.5e-248 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EPJLBGNC_00210 2.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPJLBGNC_00211 5e-23 ykzG S Belongs to the UPF0356 family
EPJLBGNC_00212 5.5e-25
EPJLBGNC_00213 6.3e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EPJLBGNC_00214 7e-31 1.1.1.27 C L-malate dehydrogenase activity
EPJLBGNC_00215 1.5e-24 yktA S Belongs to the UPF0223 family
EPJLBGNC_00216 2.2e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
EPJLBGNC_00217 0.0 typA T GTP-binding protein TypA
EPJLBGNC_00218 1.6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
EPJLBGNC_00219 3.2e-115 manY G PTS system
EPJLBGNC_00220 3.6e-147 manN G system, mannose fructose sorbose family IID component
EPJLBGNC_00221 2.3e-101 ftsW D Belongs to the SEDS family
EPJLBGNC_00222 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EPJLBGNC_00223 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
EPJLBGNC_00224 8e-73 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
EPJLBGNC_00225 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EPJLBGNC_00226 2.4e-131 ylbL T Belongs to the peptidase S16 family
EPJLBGNC_00227 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EPJLBGNC_00228 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPJLBGNC_00229 1.2e-102 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPJLBGNC_00230 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPJLBGNC_00231 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EPJLBGNC_00232 5.3e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EPJLBGNC_00233 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EPJLBGNC_00234 1.4e-233 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EPJLBGNC_00235 6.4e-163 purD 6.3.4.13 F Belongs to the GARS family
EPJLBGNC_00236 2.2e-108 S Acyltransferase family
EPJLBGNC_00237 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPJLBGNC_00238 3e-122 K LysR substrate binding domain
EPJLBGNC_00240 2.9e-20
EPJLBGNC_00241 4e-58 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EPJLBGNC_00242 4.2e-266 argS 6.1.1.19 J Arginyl-tRNA synthetase
EPJLBGNC_00243 1.2e-49 comEA L Competence protein ComEA
EPJLBGNC_00244 2e-69 comEB 3.5.4.12 F ComE operon protein 2
EPJLBGNC_00245 9.4e-157 comEC S Competence protein ComEC
EPJLBGNC_00246 3.5e-103 holA 2.7.7.7 L DNA polymerase III delta subunit
EPJLBGNC_00247 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EPJLBGNC_00248 1.9e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
EPJLBGNC_00249 3.7e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
EPJLBGNC_00250 4e-93 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EPJLBGNC_00251 3.1e-226 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EPJLBGNC_00252 1.9e-33 ypmB S Protein conserved in bacteria
EPJLBGNC_00253 5.8e-142 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EPJLBGNC_00254 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
EPJLBGNC_00255 8.5e-56 dnaD L DnaD domain protein
EPJLBGNC_00256 1.7e-82 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EPJLBGNC_00257 7.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPJLBGNC_00258 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EPJLBGNC_00259 1.4e-91 M transferase activity, transferring glycosyl groups
EPJLBGNC_00260 8e-87 M Glycosyltransferase sugar-binding region containing DXD motif
EPJLBGNC_00261 6.8e-101 epsJ1 M Glycosyltransferase like family 2
EPJLBGNC_00264 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EPJLBGNC_00265 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EPJLBGNC_00266 1.8e-56 yqeY S YqeY-like protein
EPJLBGNC_00268 1.8e-68 xerD L Phage integrase, N-terminal SAM-like domain
EPJLBGNC_00269 1.3e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EPJLBGNC_00270 1.4e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EPJLBGNC_00271 1.5e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EPJLBGNC_00272 5e-276 yfmR S ABC transporter, ATP-binding protein
EPJLBGNC_00273 2.6e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EPJLBGNC_00274 1.2e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EPJLBGNC_00275 1.8e-132 yvgN C Aldo keto reductase
EPJLBGNC_00276 2.7e-34 K helix_turn_helix, mercury resistance
EPJLBGNC_00277 2.1e-113 S Aldo keto reductase
EPJLBGNC_00279 2.9e-80 ypmR E GDSL-like Lipase/Acylhydrolase
EPJLBGNC_00280 1.2e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
EPJLBGNC_00281 3.6e-24 yozE S Belongs to the UPF0346 family
EPJLBGNC_00282 2.1e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EPJLBGNC_00283 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPJLBGNC_00284 3.3e-86 dprA LU DNA protecting protein DprA
EPJLBGNC_00285 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPJLBGNC_00286 1.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EPJLBGNC_00287 1.5e-205 G PTS system Galactitol-specific IIC component
EPJLBGNC_00288 6.5e-34 cas6 S Pfam:DUF2276
EPJLBGNC_00289 7.2e-205 csm1 S CRISPR-associated protein Csm1 family
EPJLBGNC_00290 6e-29 csm2 L Csm2 Type III-A
EPJLBGNC_00291 9.8e-70 csm3 L RAMP superfamily
EPJLBGNC_00292 5.1e-61 csm4 L CRISPR-associated RAMP protein, Csm4 family
EPJLBGNC_00293 5e-70 csm5 L RAMP superfamily
EPJLBGNC_00294 1.9e-87 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EPJLBGNC_00295 1.1e-31 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EPJLBGNC_00296 6.7e-72 csm6 S Psort location Cytoplasmic, score
EPJLBGNC_00297 1.8e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
EPJLBGNC_00298 3.3e-41 S Repeat protein
EPJLBGNC_00299 1.2e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EPJLBGNC_00301 1.7e-15
EPJLBGNC_00304 1.7e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPJLBGNC_00305 3.6e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
EPJLBGNC_00306 6.9e-43 yodB K Transcriptional regulator, HxlR family
EPJLBGNC_00307 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EPJLBGNC_00308 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EPJLBGNC_00309 1.2e-128 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EPJLBGNC_00310 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
EPJLBGNC_00311 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EPJLBGNC_00312 1.6e-10
EPJLBGNC_00313 1.1e-143 iunH2 3.2.2.1 F nucleoside hydrolase
EPJLBGNC_00314 3.8e-42 XK27_03960 S Protein of unknown function (DUF3013)
EPJLBGNC_00315 1.5e-118 prmA J Ribosomal protein L11 methyltransferase
EPJLBGNC_00316 2.2e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EPJLBGNC_00317 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EPJLBGNC_00318 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EPJLBGNC_00319 2.5e-56 3.1.3.18 J HAD-hyrolase-like
EPJLBGNC_00320 2.3e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EPJLBGNC_00321 9.6e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EPJLBGNC_00322 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EPJLBGNC_00323 2.9e-203 pyrP F Permease
EPJLBGNC_00324 2.2e-114 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EPJLBGNC_00325 1.5e-190 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EPJLBGNC_00326 1.8e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EPJLBGNC_00327 9.7e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EPJLBGNC_00328 1.6e-134 K Transcriptional regulator
EPJLBGNC_00329 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
EPJLBGNC_00330 8.6e-115 glcR K DeoR C terminal sensor domain
EPJLBGNC_00331 4.5e-171 patA 2.6.1.1 E Aminotransferase
EPJLBGNC_00332 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EPJLBGNC_00334 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EPJLBGNC_00335 3e-172 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EPJLBGNC_00336 1.4e-36 rnhA 3.1.26.4 L Ribonuclease HI
EPJLBGNC_00337 9.5e-22 S Family of unknown function (DUF5322)
EPJLBGNC_00338 5.9e-257 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
EPJLBGNC_00339 6.1e-39
EPJLBGNC_00342 1.1e-149 EGP Sugar (and other) transporter
EPJLBGNC_00343 1e-77 trmK 2.1.1.217 S SAM-dependent methyltransferase
EPJLBGNC_00344 1.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EPJLBGNC_00345 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EPJLBGNC_00346 2.5e-70 alkD L DNA alkylation repair enzyme
EPJLBGNC_00347 4.9e-136 EG EamA-like transporter family
EPJLBGNC_00348 2.8e-150 S Tetratricopeptide repeat protein
EPJLBGNC_00349 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
EPJLBGNC_00350 1.5e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EPJLBGNC_00351 7e-127 corA P CorA-like Mg2+ transporter protein
EPJLBGNC_00352 7.2e-160 nhaC C Na H antiporter NhaC
EPJLBGNC_00353 3.6e-129 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EPJLBGNC_00354 2.6e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
EPJLBGNC_00356 4.6e-91 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EPJLBGNC_00357 4.6e-160 iscS 2.8.1.7 E Aminotransferase class V
EPJLBGNC_00358 1.4e-40 XK27_04120 S Putative amino acid metabolism
EPJLBGNC_00359 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EPJLBGNC_00360 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EPJLBGNC_00361 4.3e-15 S Protein of unknown function (DUF2929)
EPJLBGNC_00362 0.0 dnaE 2.7.7.7 L DNA polymerase
EPJLBGNC_00363 1.5e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EPJLBGNC_00364 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EPJLBGNC_00366 1e-39 ypaA S Protein of unknown function (DUF1304)
EPJLBGNC_00367 4.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EPJLBGNC_00368 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EPJLBGNC_00369 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EPJLBGNC_00370 9.4e-202 FbpA K Fibronectin-binding protein
EPJLBGNC_00371 8.9e-40 K Transcriptional regulator
EPJLBGNC_00372 8.2e-117 degV S EDD domain protein, DegV family
EPJLBGNC_00373 2.5e-69 lepB 3.4.21.89 U Signal peptidase, peptidase S26
EPJLBGNC_00374 2.4e-40 6.3.3.2 S ASCH
EPJLBGNC_00375 1.3e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EPJLBGNC_00376 4.5e-80 yjjH S Calcineurin-like phosphoesterase
EPJLBGNC_00377 7e-95 EG EamA-like transporter family
EPJLBGNC_00378 6.5e-80 natB CP ABC-type Na efflux pump, permease component
EPJLBGNC_00379 3.7e-112 natA S Domain of unknown function (DUF4162)
EPJLBGNC_00380 1.8e-22 K Acetyltransferase (GNAT) domain
EPJLBGNC_00382 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EPJLBGNC_00383 5.9e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EPJLBGNC_00384 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
EPJLBGNC_00385 5.3e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
EPJLBGNC_00386 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EPJLBGNC_00387 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPJLBGNC_00388 7e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
EPJLBGNC_00389 3.4e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPJLBGNC_00390 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
EPJLBGNC_00391 5.9e-90 recO L Involved in DNA repair and RecF pathway recombination
EPJLBGNC_00392 3.5e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EPJLBGNC_00393 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EPJLBGNC_00394 1.9e-59 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EPJLBGNC_00395 5.4e-154 phoH T phosphate starvation-inducible protein PhoH
EPJLBGNC_00396 4.4e-83 lytH 3.5.1.28 M Ami_3
EPJLBGNC_00397 3.7e-85 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EPJLBGNC_00398 7.7e-12 M Lysin motif
EPJLBGNC_00399 2e-128 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
EPJLBGNC_00400 7.6e-61 ypbB 5.1.3.1 S Helix-turn-helix domain
EPJLBGNC_00401 6.4e-221 mntH P H( )-stimulated, divalent metal cation uptake system
EPJLBGNC_00402 7.9e-45 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
EPJLBGNC_00403 1.1e-120 ica2 GT2 M Glycosyl transferase family group 2
EPJLBGNC_00404 2.2e-44
EPJLBGNC_00405 2.7e-94 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EPJLBGNC_00407 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EPJLBGNC_00408 7.6e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EPJLBGNC_00409 1.6e-280 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EPJLBGNC_00410 3.1e-167 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EPJLBGNC_00411 5.9e-53 EGP Major Facilitator Superfamily
EPJLBGNC_00412 1.6e-38 K Transcriptional regulator
EPJLBGNC_00413 9.9e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
EPJLBGNC_00414 4.8e-68 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPJLBGNC_00416 1.1e-80 XK27_07525 3.6.1.55 F Hydrolase, nudix family
EPJLBGNC_00417 2.8e-56 3.6.1.27 I Acid phosphatase homologues
EPJLBGNC_00418 6.7e-68 maa 2.3.1.79 S Maltose acetyltransferase
EPJLBGNC_00419 6.3e-73 2.3.1.178 M GNAT acetyltransferase
EPJLBGNC_00421 6e-196 ade 3.5.4.2 F Adenine deaminase C-terminal domain
EPJLBGNC_00422 6e-65 ypsA S Belongs to the UPF0398 family
EPJLBGNC_00423 1.8e-125 nhaC C Na H antiporter NhaC
EPJLBGNC_00424 2.2e-54 nhaC C Na H antiporter NhaC
EPJLBGNC_00425 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EPJLBGNC_00426 1.9e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
EPJLBGNC_00427 9.6e-113 xerD D recombinase XerD
EPJLBGNC_00428 9.6e-126 cvfB S S1 domain
EPJLBGNC_00429 7e-51 yeaL S Protein of unknown function (DUF441)
EPJLBGNC_00430 1.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EPJLBGNC_00431 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EPJLBGNC_00432 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EPJLBGNC_00433 1.2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EPJLBGNC_00434 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPJLBGNC_00435 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EPJLBGNC_00436 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EPJLBGNC_00437 1e-122 xerC D Belongs to the 'phage' integrase family. XerC subfamily
EPJLBGNC_00438 2.5e-177 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
EPJLBGNC_00439 1.4e-101 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
EPJLBGNC_00440 3.1e-71
EPJLBGNC_00444 1e-12
EPJLBGNC_00445 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EPJLBGNC_00446 2.9e-27 ysxB J Cysteine protease Prp
EPJLBGNC_00447 4.9e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
EPJLBGNC_00450 2.2e-08 S Protein of unknown function (DUF2922)
EPJLBGNC_00452 2.9e-16 K DNA-templated transcription, initiation
EPJLBGNC_00454 1.6e-65 H Methyltransferase domain
EPJLBGNC_00455 2.4e-39 wecD M Acetyltransferase (GNAT) family
EPJLBGNC_00457 7.3e-27 ybl78 L Conserved phage C-terminus (Phg_2220_C)
EPJLBGNC_00458 5.7e-41 S Protein of unknown function (DUF1211)
EPJLBGNC_00460 5e-71 1.1.1.1 C Zinc-binding dehydrogenase
EPJLBGNC_00461 3.6e-39 K Transcriptional regulator
EPJLBGNC_00462 1.7e-82 qorB 1.6.5.2 GM NmrA-like family
EPJLBGNC_00465 5.6e-126 M Glycosyl transferases group 1
EPJLBGNC_00466 6.9e-65 M Glycosyl transferases group 1
EPJLBGNC_00467 1.1e-178 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EPJLBGNC_00468 6.1e-146 lspL 5.1.3.6 GM RmlD substrate binding domain
EPJLBGNC_00469 6.9e-103 cps2I S Psort location CytoplasmicMembrane, score
EPJLBGNC_00470 4.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
EPJLBGNC_00471 2.3e-116 S Glycosyltransferase WbsX
EPJLBGNC_00472 1.6e-52
EPJLBGNC_00474 2.5e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
EPJLBGNC_00475 1.7e-42 GT2 V Glycosyl transferase, family 2
EPJLBGNC_00476 1.3e-74 M Glycosyltransferase Family 4
EPJLBGNC_00477 9.3e-60 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
EPJLBGNC_00479 8.1e-80 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
EPJLBGNC_00480 1.9e-123 2.4.1.52 GT4 M Glycosyl transferases group 1
EPJLBGNC_00481 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
EPJLBGNC_00482 4.8e-77 epsL M Bacterial sugar transferase
EPJLBGNC_00483 1.7e-165 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
EPJLBGNC_00484 9.8e-127 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
EPJLBGNC_00485 7.9e-89 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
EPJLBGNC_00486 9.4e-65 cpsD D AAA domain
EPJLBGNC_00487 1.8e-48 cps4C M Chain length determinant protein
EPJLBGNC_00488 6.7e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
EPJLBGNC_00489 3.8e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EPJLBGNC_00490 4.8e-81
EPJLBGNC_00491 1.8e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
EPJLBGNC_00492 5.1e-113 yitU 3.1.3.104 S hydrolase
EPJLBGNC_00493 3e-61 speG J Acetyltransferase (GNAT) domain
EPJLBGNC_00494 2.4e-189 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EPJLBGNC_00495 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
EPJLBGNC_00496 5e-204 pipD E Dipeptidase
EPJLBGNC_00497 1.1e-44
EPJLBGNC_00498 3.5e-64 K helix_turn_helix, arabinose operon control protein
EPJLBGNC_00499 8.9e-54 S Membrane
EPJLBGNC_00500 0.0 rafA 3.2.1.22 G alpha-galactosidase
EPJLBGNC_00501 2.6e-308 L Helicase C-terminal domain protein
EPJLBGNC_00502 1.9e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
EPJLBGNC_00503 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
EPJLBGNC_00504 2.4e-113 2.7.7.65 T diguanylate cyclase activity
EPJLBGNC_00505 3.4e-310 ydaN S Bacterial cellulose synthase subunit
EPJLBGNC_00506 7.7e-201 ydaM M Glycosyl transferase family group 2
EPJLBGNC_00507 1e-205 S Protein conserved in bacteria
EPJLBGNC_00508 9.3e-182
EPJLBGNC_00509 1.4e-81 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
EPJLBGNC_00510 9.6e-28 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
EPJLBGNC_00511 8.1e-43 2.7.7.65 T GGDEF domain
EPJLBGNC_00512 1.5e-146 pbuO_1 S Permease family
EPJLBGNC_00513 9.5e-156 ndh 1.6.99.3 C NADH dehydrogenase
EPJLBGNC_00514 3.3e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
EPJLBGNC_00515 6.2e-97 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EPJLBGNC_00516 3.6e-220 cydD CO ABC transporter transmembrane region
EPJLBGNC_00517 7.8e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
EPJLBGNC_00518 5.6e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
EPJLBGNC_00519 3e-193 cydA 1.10.3.14 C ubiquinol oxidase
EPJLBGNC_00520 2.6e-159 asnA 6.3.1.1 F aspartate--ammonia ligase
EPJLBGNC_00521 5.7e-29 xlyB 3.5.1.28 CBM50 M LysM domain
EPJLBGNC_00522 2.3e-19 glpE P Rhodanese Homology Domain
EPJLBGNC_00523 2.1e-48 lytE M LysM domain protein
EPJLBGNC_00524 4.8e-93 T Calcineurin-like phosphoesterase superfamily domain
EPJLBGNC_00525 1.9e-85 2.7.7.12 C Domain of unknown function (DUF4931)
EPJLBGNC_00527 3.3e-74 draG O ADP-ribosylglycohydrolase
EPJLBGNC_00528 4.4e-91 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EPJLBGNC_00529 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EPJLBGNC_00530 5.1e-62 divIVA D DivIVA domain protein
EPJLBGNC_00531 7.7e-82 ylmH S S4 domain protein
EPJLBGNC_00532 3e-19 yggT S YGGT family
EPJLBGNC_00533 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EPJLBGNC_00534 2.9e-179 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EPJLBGNC_00535 4.4e-189 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EPJLBGNC_00536 5.7e-62 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EPJLBGNC_00537 6.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EPJLBGNC_00538 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EPJLBGNC_00539 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EPJLBGNC_00540 6.9e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
EPJLBGNC_00541 2.5e-11 ftsL D cell division protein FtsL
EPJLBGNC_00542 3.6e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EPJLBGNC_00543 5.2e-64 mraZ K Belongs to the MraZ family
EPJLBGNC_00544 4.5e-08 S Protein of unknown function (DUF3397)
EPJLBGNC_00545 2.7e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
EPJLBGNC_00547 7.5e-100 D Alpha beta
EPJLBGNC_00548 1.4e-108 aatB ET ABC transporter substrate-binding protein
EPJLBGNC_00549 1.1e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EPJLBGNC_00550 1.9e-94 glnP P ABC transporter permease
EPJLBGNC_00551 3.1e-126 minD D Belongs to the ParA family
EPJLBGNC_00552 3.2e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EPJLBGNC_00553 4.4e-54 mreD M rod shape-determining protein MreD
EPJLBGNC_00554 2.1e-88 mreC M Involved in formation and maintenance of cell shape
EPJLBGNC_00555 3.6e-156 mreB D cell shape determining protein MreB
EPJLBGNC_00556 4.5e-21 K Cold shock
EPJLBGNC_00557 6.2e-80 radC L DNA repair protein
EPJLBGNC_00558 1.4e-136 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EPJLBGNC_00559 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EPJLBGNC_00560 4.2e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EPJLBGNC_00561 2.2e-162 iscS2 2.8.1.7 E Aminotransferase class V
EPJLBGNC_00562 2.1e-172 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EPJLBGNC_00563 1.6e-55 ytsP 1.8.4.14 T GAF domain-containing protein
EPJLBGNC_00564 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EPJLBGNC_00565 5.9e-24 yueI S Protein of unknown function (DUF1694)
EPJLBGNC_00566 4.9e-187 rarA L recombination factor protein RarA
EPJLBGNC_00568 3.2e-73 usp6 T universal stress protein
EPJLBGNC_00569 1.2e-52 tag 3.2.2.20 L glycosylase
EPJLBGNC_00570 5e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EPJLBGNC_00571 5e-124 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
EPJLBGNC_00574 1.8e-45 yviA S Protein of unknown function (DUF421)
EPJLBGNC_00576 1.2e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
EPJLBGNC_00577 8.4e-298 S membrane
EPJLBGNC_00578 2.8e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EPJLBGNC_00579 9.9e-218 recJ L Single-stranded-DNA-specific exonuclease RecJ
EPJLBGNC_00580 1.7e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
EPJLBGNC_00581 9.8e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EPJLBGNC_00583 1.4e-16
EPJLBGNC_00584 1.3e-199 oatA I Acyltransferase
EPJLBGNC_00585 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EPJLBGNC_00586 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EPJLBGNC_00587 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPJLBGNC_00590 4.4e-41 S Phosphoesterase
EPJLBGNC_00591 5.5e-72 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EPJLBGNC_00592 1.1e-60 yslB S Protein of unknown function (DUF2507)
EPJLBGNC_00593 9.9e-41 trxA O Belongs to the thioredoxin family
EPJLBGNC_00594 7.2e-309 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EPJLBGNC_00595 1.6e-17 cvpA S Colicin V production protein
EPJLBGNC_00596 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EPJLBGNC_00597 1.9e-33 yrzB S Belongs to the UPF0473 family
EPJLBGNC_00598 8.8e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EPJLBGNC_00599 2.1e-36 yrzL S Belongs to the UPF0297 family
EPJLBGNC_00600 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EPJLBGNC_00601 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EPJLBGNC_00602 1.2e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
EPJLBGNC_00603 7.5e-13
EPJLBGNC_00604 3.9e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPJLBGNC_00605 1.6e-65 yrjD S LUD domain
EPJLBGNC_00606 4e-244 lutB C 4Fe-4S dicluster domain
EPJLBGNC_00607 2e-116 lutA C Cysteine-rich domain
EPJLBGNC_00608 2e-208 yfnA E Amino Acid
EPJLBGNC_00610 4.3e-61 uspA T universal stress protein
EPJLBGNC_00612 1.4e-12 yajC U Preprotein translocase
EPJLBGNC_00613 7.8e-208 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EPJLBGNC_00614 7.9e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EPJLBGNC_00615 8.2e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EPJLBGNC_00616 1.6e-71 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EPJLBGNC_00617 4.9e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EPJLBGNC_00618 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EPJLBGNC_00619 5e-181 rny S Endoribonuclease that initiates mRNA decay
EPJLBGNC_00620 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EPJLBGNC_00621 8e-84 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPJLBGNC_00622 8.5e-64 ymfM S Helix-turn-helix domain
EPJLBGNC_00623 4.9e-91 IQ Enoyl-(Acyl carrier protein) reductase
EPJLBGNC_00624 9.3e-149 ymfH S Peptidase M16
EPJLBGNC_00625 2e-108 ymfF S Peptidase M16 inactive domain protein
EPJLBGNC_00626 6.8e-288 ftsK D Belongs to the FtsK SpoIIIE SftA family
EPJLBGNC_00627 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EPJLBGNC_00628 5.8e-99 rrmA 2.1.1.187 H Methyltransferase
EPJLBGNC_00629 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
EPJLBGNC_00630 5e-163 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EPJLBGNC_00631 8.1e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPJLBGNC_00632 4.9e-94 S Bacterial membrane protein, YfhO
EPJLBGNC_00634 2.3e-19 cutC P Participates in the control of copper homeostasis
EPJLBGNC_00635 4.9e-129 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
EPJLBGNC_00636 5.8e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
EPJLBGNC_00637 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EPJLBGNC_00638 5.3e-68 ybbR S YbbR-like protein
EPJLBGNC_00639 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EPJLBGNC_00640 2.4e-71 S Protein of unknown function (DUF1361)
EPJLBGNC_00641 6e-115 murB 1.3.1.98 M Cell wall formation
EPJLBGNC_00642 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
EPJLBGNC_00643 4.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
EPJLBGNC_00644 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EPJLBGNC_00645 1.5e-105 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EPJLBGNC_00646 2.4e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
EPJLBGNC_00647 3.1e-42 yxjI
EPJLBGNC_00648 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EPJLBGNC_00649 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EPJLBGNC_00650 2.8e-19 secG U Preprotein translocase
EPJLBGNC_00651 3.5e-179 clcA P chloride
EPJLBGNC_00652 1.1e-145 lmrP E Major Facilitator Superfamily
EPJLBGNC_00653 1.8e-169 T PhoQ Sensor
EPJLBGNC_00654 7.2e-103 K response regulator
EPJLBGNC_00655 1.4e-131 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPJLBGNC_00656 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EPJLBGNC_00657 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EPJLBGNC_00658 1.1e-207 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EPJLBGNC_00659 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EPJLBGNC_00660 4.2e-136 cggR K Putative sugar-binding domain
EPJLBGNC_00662 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EPJLBGNC_00663 1.8e-149 whiA K May be required for sporulation
EPJLBGNC_00664 6.3e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EPJLBGNC_00665 7.5e-126 rapZ S Displays ATPase and GTPase activities
EPJLBGNC_00666 1.3e-79 ylbE GM NAD dependent epimerase dehydratase family protein
EPJLBGNC_00667 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EPJLBGNC_00668 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EPJLBGNC_00669 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EPJLBGNC_00670 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EPJLBGNC_00671 3.3e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EPJLBGNC_00672 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EPJLBGNC_00673 3.5e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
EPJLBGNC_00674 4.1e-08 KT PspC domain protein
EPJLBGNC_00675 5.3e-86 phoR 2.7.13.3 T Histidine kinase
EPJLBGNC_00676 1.3e-85 K response regulator
EPJLBGNC_00677 9.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
EPJLBGNC_00678 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EPJLBGNC_00679 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EPJLBGNC_00680 9.1e-95 yeaN P Major Facilitator Superfamily
EPJLBGNC_00681 2.1e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EPJLBGNC_00682 3e-50 comFC S Competence protein
EPJLBGNC_00683 1.9e-128 comFA L Helicase C-terminal domain protein
EPJLBGNC_00684 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
EPJLBGNC_00685 4.9e-297 ydaO E amino acid
EPJLBGNC_00686 5.7e-269 aha1 P COG COG0474 Cation transport ATPase
EPJLBGNC_00687 1.1e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EPJLBGNC_00688 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EPJLBGNC_00689 1.3e-31 S CAAX protease self-immunity
EPJLBGNC_00690 9.7e-99 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EPJLBGNC_00691 2.6e-256 uup S ABC transporter, ATP-binding protein
EPJLBGNC_00692 9.2e-160 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EPJLBGNC_00693 1.1e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
EPJLBGNC_00694 8.2e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
EPJLBGNC_00695 1.2e-140 ansA 3.5.1.1 EJ Asparaginase
EPJLBGNC_00696 7.2e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
EPJLBGNC_00697 3.3e-105 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EPJLBGNC_00698 1.4e-40 yabA L Involved in initiation control of chromosome replication
EPJLBGNC_00699 3e-83 holB 2.7.7.7 L DNA polymerase III
EPJLBGNC_00700 8.1e-66 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EPJLBGNC_00701 7.1e-29 yaaL S Protein of unknown function (DUF2508)
EPJLBGNC_00702 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EPJLBGNC_00703 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EPJLBGNC_00704 4.6e-212 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPJLBGNC_00705 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EPJLBGNC_00706 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
EPJLBGNC_00707 1.2e-27 nrdH O Glutaredoxin
EPJLBGNC_00708 4.8e-45 nrdI F NrdI Flavodoxin like
EPJLBGNC_00709 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPJLBGNC_00710 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPJLBGNC_00711 2.7e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EPJLBGNC_00712 1.6e-55
EPJLBGNC_00713 1.3e-47 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EPJLBGNC_00714 1.7e-74 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EPJLBGNC_00715 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EPJLBGNC_00716 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EPJLBGNC_00717 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
EPJLBGNC_00718 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EPJLBGNC_00719 3.1e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EPJLBGNC_00720 7e-71 yacP S YacP-like NYN domain
EPJLBGNC_00721 1.2e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPJLBGNC_00722 3.8e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EPJLBGNC_00723 2.8e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EPJLBGNC_00724 1.4e-246 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EPJLBGNC_00725 8.2e-154 yacL S domain protein
EPJLBGNC_00726 3.5e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EPJLBGNC_00727 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
EPJLBGNC_00728 8.1e-18 HA62_12640 S GCN5-related N-acetyl-transferase
EPJLBGNC_00729 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
EPJLBGNC_00730 1e-33 S Enterocin A Immunity
EPJLBGNC_00731 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EPJLBGNC_00732 1.1e-127 mleP2 S Sodium Bile acid symporter family
EPJLBGNC_00733 3.5e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPJLBGNC_00735 3e-43 ydcK S Belongs to the SprT family
EPJLBGNC_00736 2.2e-251 yhgF K Tex-like protein N-terminal domain protein
EPJLBGNC_00737 1.8e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EPJLBGNC_00738 9.5e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EPJLBGNC_00739 1.4e-90 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EPJLBGNC_00740 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
EPJLBGNC_00741 1e-89 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPJLBGNC_00743 1.1e-07
EPJLBGNC_00744 1.6e-197 dtpT U amino acid peptide transporter
EPJLBGNC_00748 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
EPJLBGNC_00749 2.3e-46 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EPJLBGNC_00750 6.6e-69 coiA 3.6.4.12 S Competence protein
EPJLBGNC_00751 1.2e-229 pepF E oligoendopeptidase F
EPJLBGNC_00752 2.3e-41 yjbH Q Thioredoxin
EPJLBGNC_00753 1.9e-97 pstS P Phosphate
EPJLBGNC_00754 7e-119 pstC P probably responsible for the translocation of the substrate across the membrane
EPJLBGNC_00755 3.9e-122 pstA P Phosphate transport system permease protein PstA
EPJLBGNC_00756 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EPJLBGNC_00757 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EPJLBGNC_00758 3.6e-56 P Plays a role in the regulation of phosphate uptake
EPJLBGNC_00759 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
EPJLBGNC_00760 1.1e-79 S VIT family
EPJLBGNC_00761 9.4e-84 S membrane
EPJLBGNC_00762 1.1e-39 M1-874 K Domain of unknown function (DUF1836)
EPJLBGNC_00763 1.8e-65 hly S protein, hemolysin III
EPJLBGNC_00764 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
EPJLBGNC_00765 1.3e-74 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPJLBGNC_00768 5.1e-14
EPJLBGNC_00769 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
EPJLBGNC_00770 1.1e-157 ccpA K catabolite control protein A
EPJLBGNC_00771 1.1e-41 S VanZ like family
EPJLBGNC_00772 1.5e-119 yebC K Transcriptional regulatory protein
EPJLBGNC_00773 1.5e-100 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPJLBGNC_00774 1.1e-120 comGA NU Type II IV secretion system protein
EPJLBGNC_00775 3.4e-98 comGB NU type II secretion system
EPJLBGNC_00776 1.8e-26 comGC U competence protein ComGC
EPJLBGNC_00777 5e-14
EPJLBGNC_00779 1.6e-10 S Putative Competence protein ComGF
EPJLBGNC_00781 5.8e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
EPJLBGNC_00782 2.7e-183 cycA E Amino acid permease
EPJLBGNC_00783 3e-57 S Calcineurin-like phosphoesterase
EPJLBGNC_00784 1.9e-53 yutD S Protein of unknown function (DUF1027)
EPJLBGNC_00785 8.3e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EPJLBGNC_00786 4.6e-32 S Protein of unknown function (DUF1461)
EPJLBGNC_00787 3e-92 dedA S SNARE associated Golgi protein
EPJLBGNC_00788 2.3e-94 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EPJLBGNC_00789 1.1e-49 yugI 5.3.1.9 J general stress protein
EPJLBGNC_00790 1e-25 tnpR L Resolvase, N terminal domain
EPJLBGNC_00791 1.5e-100 pncA Q Isochorismatase family
EPJLBGNC_00792 6.2e-271 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EPJLBGNC_00793 1.1e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
EPJLBGNC_00794 6.2e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
EPJLBGNC_00795 2.6e-55 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
EPJLBGNC_00796 2.8e-148 D CobQ CobB MinD ParA nucleotide binding domain protein
EPJLBGNC_00797 1.7e-35
EPJLBGNC_00798 1.8e-166 repA S Replication initiator protein A
EPJLBGNC_00799 1e-131 S Fic/DOC family
EPJLBGNC_00800 1.1e-38 relB L Addiction module antitoxin, RelB DinJ family
EPJLBGNC_00801 1.2e-25
EPJLBGNC_00802 2.5e-113 S protein conserved in bacteria
EPJLBGNC_00803 2e-40
EPJLBGNC_00804 2.5e-27
EPJLBGNC_00805 0.0 traA L MobA MobL family protein
EPJLBGNC_00806 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EPJLBGNC_00807 4.7e-210 glnP P ABC transporter
EPJLBGNC_00809 1.1e-59 uspA T Universal stress protein family
EPJLBGNC_00810 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
EPJLBGNC_00811 1.1e-25
EPJLBGNC_00812 1.4e-200 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
EPJLBGNC_00813 8e-110 puuD S peptidase C26
EPJLBGNC_00814 1.4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EPJLBGNC_00815 3.3e-150 lsa S ABC transporter
EPJLBGNC_00816 9.4e-149 mepA V MATE efflux family protein
EPJLBGNC_00817 8.9e-248 gshR 1.8.1.7 C Glutathione reductase
EPJLBGNC_00818 1.1e-178 proV E ABC transporter, ATP-binding protein
EPJLBGNC_00819 1.2e-262 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EPJLBGNC_00820 1.2e-149 cbiO2 P ABC transporter
EPJLBGNC_00821 1.3e-156 P ABC transporter
EPJLBGNC_00822 1.3e-132 cbiQ P Cobalt transport protein
EPJLBGNC_00823 8.5e-89 2.7.7.65 T phosphorelay sensor kinase activity
EPJLBGNC_00824 5.9e-206 M Cna protein B-type domain
EPJLBGNC_00825 3.9e-259 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
EPJLBGNC_00826 1e-99 K Bacterial regulatory proteins, tetR family
EPJLBGNC_00827 3.3e-293 norB EGP Major Facilitator
EPJLBGNC_00829 4e-44
EPJLBGNC_00830 1e-39 S RelB antitoxin
EPJLBGNC_00831 2.5e-107
EPJLBGNC_00834 5.9e-42 hxlR K Transcriptional regulator, HxlR family
EPJLBGNC_00835 5.7e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
EPJLBGNC_00836 1.9e-92
EPJLBGNC_00837 4.2e-48 L Transposase
EPJLBGNC_00839 6.9e-57 K SIR2-like domain
EPJLBGNC_00840 9.3e-21
EPJLBGNC_00841 8.5e-64 V HNH endonuclease
EPJLBGNC_00843 1.3e-12
EPJLBGNC_00844 4.6e-79
EPJLBGNC_00852 1.7e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EPJLBGNC_00853 1.4e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EPJLBGNC_00854 1.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EPJLBGNC_00855 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EPJLBGNC_00856 2.5e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EPJLBGNC_00858 1.6e-55 ctsR K Belongs to the CtsR family
EPJLBGNC_00859 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EPJLBGNC_00860 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPJLBGNC_00861 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPJLBGNC_00862 1.9e-23 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
EPJLBGNC_00863 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EPJLBGNC_00864 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EPJLBGNC_00865 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EPJLBGNC_00866 9e-93 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EPJLBGNC_00867 6.8e-90 patB 4.4.1.8 E Aminotransferase, class I
EPJLBGNC_00868 1.4e-111 K response regulator
EPJLBGNC_00869 8.8e-143 hpk31 2.7.13.3 T Histidine kinase
EPJLBGNC_00870 2.5e-89 lacX 5.1.3.3 G Aldose 1-epimerase
EPJLBGNC_00871 1e-146 G Transporter, major facilitator family protein
EPJLBGNC_00872 2.9e-222 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EPJLBGNC_00873 4e-244 yhcA V ABC transporter, ATP-binding protein
EPJLBGNC_00874 3.8e-34 K Bacterial regulatory proteins, tetR family
EPJLBGNC_00875 1.3e-222 lmrA V ABC transporter, ATP-binding protein
EPJLBGNC_00876 3.3e-253 yfiC V ABC transporter
EPJLBGNC_00878 1.1e-45 yjcF K protein acetylation
EPJLBGNC_00879 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
EPJLBGNC_00880 3e-72 lemA S LemA family
EPJLBGNC_00881 1.7e-109 htpX O Belongs to the peptidase M48B family
EPJLBGNC_00883 1.4e-269 helD 3.6.4.12 L DNA helicase
EPJLBGNC_00884 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPJLBGNC_00885 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
EPJLBGNC_00886 1.6e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
EPJLBGNC_00887 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
EPJLBGNC_00888 2.4e-105 ybhR V ABC transporter
EPJLBGNC_00889 3.9e-31 K Transcriptional regulator
EPJLBGNC_00890 4.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
EPJLBGNC_00891 1.8e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
EPJLBGNC_00892 5.6e-127
EPJLBGNC_00893 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPJLBGNC_00894 1.7e-102 tatD L hydrolase, TatD family
EPJLBGNC_00895 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EPJLBGNC_00896 1.4e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EPJLBGNC_00897 1.2e-22 veg S Biofilm formation stimulator VEG
EPJLBGNC_00898 5.7e-91 S Alpha/beta hydrolase of unknown function (DUF915)
EPJLBGNC_00899 1e-132 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
EPJLBGNC_00900 6.6e-46 argR K Regulates arginine biosynthesis genes
EPJLBGNC_00901 8.2e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EPJLBGNC_00902 6.7e-155 amtB P ammonium transporter
EPJLBGNC_00903 6.6e-90 sip L Belongs to the 'phage' integrase family
EPJLBGNC_00904 1.9e-31 S ParE toxin of type II toxin-antitoxin system, parDE
EPJLBGNC_00905 9.7e-23
EPJLBGNC_00907 2.6e-24 S Domain of unknown function (DUF4393)
EPJLBGNC_00908 2.2e-31
EPJLBGNC_00909 9.9e-27 S Domain of unknown function (DUF4352)
EPJLBGNC_00912 4.5e-42 K Peptidase S24-like
EPJLBGNC_00916 5.9e-16
EPJLBGNC_00918 2.6e-15 K Cro/C1-type HTH DNA-binding domain
EPJLBGNC_00919 2.4e-13 cro K Helix-turn-helix XRE-family like proteins
EPJLBGNC_00920 4.6e-81 S DNA binding
EPJLBGNC_00925 1.7e-54 S Putative HNHc nuclease
EPJLBGNC_00926 8.6e-30 S Phage replisome organizer, N-terminal domain protein
EPJLBGNC_00929 1.6e-25
EPJLBGNC_00930 2.2e-70
EPJLBGNC_00936 7.8e-21
EPJLBGNC_00938 1.5e-59 Q DNA (cytosine-5-)-methyltransferase activity
EPJLBGNC_00942 2.3e-28 arpU S Phage transcriptional regulator, ArpU family
EPJLBGNC_00943 8.8e-12
EPJLBGNC_00946 3.9e-66 L HNH nucleases
EPJLBGNC_00947 5.3e-81 L Phage terminase, small subunit
EPJLBGNC_00948 0.0 S Phage Terminase
EPJLBGNC_00950 1.9e-193 S Phage portal protein
EPJLBGNC_00951 1e-112 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
EPJLBGNC_00952 6.5e-197 S Phage capsid family
EPJLBGNC_00953 3.7e-22 S Phage gp6-like head-tail connector protein
EPJLBGNC_00954 1.3e-49 S Phage head-tail joining protein
EPJLBGNC_00955 4.8e-54 S Bacteriophage HK97-gp10, putative tail-component
EPJLBGNC_00956 7.8e-56 S Protein of unknown function (DUF806)
EPJLBGNC_00957 1.8e-77 S Phage tail tube protein
EPJLBGNC_00958 9.8e-17 S Phage tail assembly chaperone proteins, TAC
EPJLBGNC_00960 2.2e-304 M Phage tail tape measure protein TP901
EPJLBGNC_00961 1.3e-76 S Phage tail protein
EPJLBGNC_00962 1.7e-116 rny D peptidase
EPJLBGNC_00964 1.9e-27 S Calcineurin-like phosphoesterase
EPJLBGNC_00971 1.9e-130 M Glycosyl hydrolases family 25
EPJLBGNC_00972 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
EPJLBGNC_00973 1.7e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EPJLBGNC_00974 3.4e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
EPJLBGNC_00975 9.9e-127 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPJLBGNC_00976 4.7e-103 pfoS S Phosphotransferase system, EIIC
EPJLBGNC_00977 4.6e-73 2.4.1.9 GH68 M MucBP domain
EPJLBGNC_00978 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EPJLBGNC_00979 9.6e-52 adhR K helix_turn_helix, mercury resistance
EPJLBGNC_00980 5.2e-137 purR 2.4.2.7 F pur operon repressor
EPJLBGNC_00981 4.3e-47 EGP Transmembrane secretion effector
EPJLBGNC_00982 1.5e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EPJLBGNC_00983 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPJLBGNC_00984 4.3e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPJLBGNC_00986 3.1e-113 dkg S reductase
EPJLBGNC_00987 9e-26
EPJLBGNC_00988 5.1e-78 2.4.2.3 F Phosphorylase superfamily
EPJLBGNC_00989 3.9e-290 ybiT S ABC transporter, ATP-binding protein
EPJLBGNC_00990 5.7e-62 bCE_4747 S Beta-lactamase superfamily domain
EPJLBGNC_00991 1.7e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EPJLBGNC_00992 3.9e-124 S overlaps another CDS with the same product name
EPJLBGNC_00993 2.6e-87 S overlaps another CDS with the same product name
EPJLBGNC_00995 1.1e-55 spoVK O ATPase family associated with various cellular activities (AAA)
EPJLBGNC_00996 1e-22
EPJLBGNC_00998 5.5e-26 L PIF1-like helicase
EPJLBGNC_01000 1.7e-71
EPJLBGNC_01001 3.7e-22
EPJLBGNC_01002 3.2e-103 ydcZ S Putative inner membrane exporter, YdcZ
EPJLBGNC_01003 4e-89 S hydrolase
EPJLBGNC_01004 4.3e-205 ywfO S HD domain protein
EPJLBGNC_01005 7.5e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
EPJLBGNC_01006 3.1e-32 ywiB S Domain of unknown function (DUF1934)
EPJLBGNC_01007 9.9e-42 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EPJLBGNC_01008 6.2e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EPJLBGNC_01011 4.6e-201 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPJLBGNC_01012 3.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EPJLBGNC_01013 3.6e-41 rpmE2 J Ribosomal protein L31
EPJLBGNC_01014 2.8e-61
EPJLBGNC_01015 2.6e-258 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
EPJLBGNC_01017 8e-79 S Cell surface protein
EPJLBGNC_01019 1.6e-180 pbuG S permease
EPJLBGNC_01020 4.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
EPJLBGNC_01021 5.3e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EPJLBGNC_01022 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EPJLBGNC_01023 1e-29 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EPJLBGNC_01024 8.2e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPJLBGNC_01025 5.4e-13
EPJLBGNC_01026 2e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
EPJLBGNC_01027 1.5e-91 yunF F Protein of unknown function DUF72
EPJLBGNC_01028 6.6e-156 nrnB S DHHA1 domain
EPJLBGNC_01029 1.4e-42 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EPJLBGNC_01030 4.4e-60
EPJLBGNC_01031 7.3e-47 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
EPJLBGNC_01032 7e-23 S Cytochrome B5
EPJLBGNC_01033 1.8e-19 sigH K DNA-templated transcription, initiation
EPJLBGNC_01034 4.2e-67 recX 2.4.1.337 GT4 S Regulatory protein RecX
EPJLBGNC_01035 4.7e-191 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPJLBGNC_01036 2.6e-97 ygaC J Belongs to the UPF0374 family
EPJLBGNC_01037 6.9e-92 yueF S AI-2E family transporter
EPJLBGNC_01038 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EPJLBGNC_01039 1e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EPJLBGNC_01040 2e-278 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EPJLBGNC_01041 0.0 lacL 3.2.1.23 G -beta-galactosidase
EPJLBGNC_01042 8.9e-289 lacS G Transporter
EPJLBGNC_01043 5.9e-111 galR K Transcriptional regulator
EPJLBGNC_01044 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EPJLBGNC_01045 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EPJLBGNC_01046 8.3e-202 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EPJLBGNC_01047 0.0 rafA 3.2.1.22 G alpha-galactosidase
EPJLBGNC_01048 1.1e-104 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
EPJLBGNC_01049 1.9e-22 XK27_09445 S Domain of unknown function (DUF1827)
EPJLBGNC_01050 0.0 clpE O Belongs to the ClpA ClpB family
EPJLBGNC_01051 1.5e-15
EPJLBGNC_01052 9.7e-37 ptsH G phosphocarrier protein HPR
EPJLBGNC_01053 9e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPJLBGNC_01054 1.1e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
EPJLBGNC_01055 1.3e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
EPJLBGNC_01056 1.3e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EPJLBGNC_01057 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
EPJLBGNC_01058 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EPJLBGNC_01061 2.1e-07
EPJLBGNC_01064 1.6e-75 xerC L Belongs to the 'phage' integrase family
EPJLBGNC_01065 1.8e-27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EPJLBGNC_01066 8.4e-38 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EPJLBGNC_01067 2.5e-58 cpsF M Oligosaccharide biosynthesis protein Alg14 like
EPJLBGNC_01068 2e-91 rfbP M Bacterial sugar transferase
EPJLBGNC_01069 2.7e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EPJLBGNC_01070 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EPJLBGNC_01071 1.6e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EPJLBGNC_01072 4e-129 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EPJLBGNC_01074 5.7e-43 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EPJLBGNC_01075 6.9e-92 M Core-2/I-Branching enzyme
EPJLBGNC_01076 1.3e-76 waaB GT4 M Glycosyl transferases group 1
EPJLBGNC_01077 3.4e-93 M transferase activity, transferring glycosyl groups
EPJLBGNC_01078 1.1e-57 cps3F
EPJLBGNC_01079 2.4e-73 M LicD family
EPJLBGNC_01080 2.5e-63 M Glycosyltransferase like family 2
EPJLBGNC_01083 1e-43 S Peptidase_C39 like family
EPJLBGNC_01084 1.1e-16 S Acyltransferase family
EPJLBGNC_01085 1.1e-22 S Acyltransferase family
EPJLBGNC_01086 1.2e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
EPJLBGNC_01087 1.8e-153 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
EPJLBGNC_01089 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EPJLBGNC_01090 7.3e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EPJLBGNC_01091 5.6e-97 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EPJLBGNC_01092 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
EPJLBGNC_01093 7e-157 XK27_09615 S reductase
EPJLBGNC_01094 7.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
EPJLBGNC_01095 5e-147 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
EPJLBGNC_01096 8.5e-37 S Psort location CytoplasmicMembrane, score
EPJLBGNC_01097 1.6e-35 S Psort location CytoplasmicMembrane, score
EPJLBGNC_01098 3.6e-14
EPJLBGNC_01099 9.1e-132 S Bacterial membrane protein YfhO
EPJLBGNC_01100 6e-176 thrC 4.2.3.1 E Threonine synthase
EPJLBGNC_01101 1.5e-127 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EPJLBGNC_01102 1.2e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
EPJLBGNC_01103 1.2e-88 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EPJLBGNC_01104 2.2e-177 licA 2.7.1.89 M Choline/ethanolamine kinase
EPJLBGNC_01105 1.9e-84 M Nucleotidyl transferase
EPJLBGNC_01106 1.1e-150 M BCCT, betaine/carnitine/choline family transporter
EPJLBGNC_01107 5.9e-56 S peptidoglycan catabolic process
EPJLBGNC_01108 2.1e-196 XK27_08315 M Sulfatase
EPJLBGNC_01110 1.4e-167 mdtG EGP Major facilitator Superfamily
EPJLBGNC_01111 9.8e-252 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
EPJLBGNC_01112 6.3e-83 treR K UTRA
EPJLBGNC_01113 9.5e-259 treB G phosphotransferase system
EPJLBGNC_01114 4.6e-63 3.1.3.73 G phosphoglycerate mutase
EPJLBGNC_01115 7e-82 pncA Q isochorismatase
EPJLBGNC_01116 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
EPJLBGNC_01117 3.4e-103 ydhQ K UbiC transcription regulator-associated domain protein
EPJLBGNC_01118 5e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EPJLBGNC_01119 1.3e-41 K Transcriptional regulator, HxlR family
EPJLBGNC_01120 3.2e-163 C Luciferase-like monooxygenase
EPJLBGNC_01121 5e-67 1.5.1.38 S NADPH-dependent FMN reductase
EPJLBGNC_01122 7.6e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
EPJLBGNC_01123 4.4e-75 L haloacid dehalogenase-like hydrolase
EPJLBGNC_01124 5.8e-60 EG EamA-like transporter family
EPJLBGNC_01125 4e-118 K AI-2E family transporter
EPJLBGNC_01126 1.9e-172 malY 4.4.1.8 E Aminotransferase, class I
EPJLBGNC_01127 4.6e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EPJLBGNC_01128 2.3e-59 yfjR K WYL domain
EPJLBGNC_01129 4e-11 S Mor transcription activator family
EPJLBGNC_01131 8.1e-09 S zinc-ribbon domain
EPJLBGNC_01136 3.8e-74 V domain protein
EPJLBGNC_01137 5.8e-94 V domain protein
EPJLBGNC_01138 4.9e-119 xth 3.1.11.2 L exodeoxyribonuclease III
EPJLBGNC_01139 3.5e-17
EPJLBGNC_01140 1.9e-104 azlC E AzlC protein
EPJLBGNC_01141 1.3e-38 azlD S branched-chain amino acid
EPJLBGNC_01142 2.1e-66 I alpha/beta hydrolase fold
EPJLBGNC_01143 3.1e-25
EPJLBGNC_01144 2.1e-58 3.6.1.27 I phosphatase
EPJLBGNC_01145 3.1e-23
EPJLBGNC_01146 3.1e-95 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EPJLBGNC_01147 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
EPJLBGNC_01148 3.1e-27 cspC K Cold shock protein
EPJLBGNC_01149 4.3e-82 thrE S Putative threonine/serine exporter
EPJLBGNC_01150 1.3e-49 S Threonine/Serine exporter, ThrE
EPJLBGNC_01151 2.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
EPJLBGNC_01152 3.8e-87 S Sucrose-6F-phosphate phosphohydrolase
EPJLBGNC_01153 1.9e-34 trxA O Belongs to the thioredoxin family
EPJLBGNC_01154 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPJLBGNC_01155 8.8e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPJLBGNC_01156 4.3e-65 degV S Uncharacterised protein, DegV family COG1307
EPJLBGNC_01158 4.3e-54 queT S QueT transporter
EPJLBGNC_01159 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
EPJLBGNC_01160 1.4e-101 IQ Enoyl-(Acyl carrier protein) reductase
EPJLBGNC_01161 1.3e-111 argE 3.5.1.18 E Peptidase dimerisation domain
EPJLBGNC_01162 2.1e-173 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EPJLBGNC_01163 4.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EPJLBGNC_01164 5e-87 S Alpha beta hydrolase
EPJLBGNC_01165 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPJLBGNC_01166 1.6e-140 V MatE
EPJLBGNC_01167 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
EPJLBGNC_01168 3.4e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPJLBGNC_01169 3.3e-97 V ABC transporter
EPJLBGNC_01170 1.6e-131 bacI V MacB-like periplasmic core domain
EPJLBGNC_01171 6.9e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EPJLBGNC_01172 3.7e-26
EPJLBGNC_01173 9.3e-181 yhdP S Transporter associated domain
EPJLBGNC_01174 6e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
EPJLBGNC_01175 0.0 L Helicase C-terminal domain protein
EPJLBGNC_01176 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EPJLBGNC_01177 6.3e-212 yfnA E Amino Acid
EPJLBGNC_01178 3.2e-53 zur P Belongs to the Fur family
EPJLBGNC_01180 2.9e-98
EPJLBGNC_01181 3.9e-08
EPJLBGNC_01182 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EPJLBGNC_01183 4.6e-101 glnH ET ABC transporter
EPJLBGNC_01184 9.3e-86 gluC P ABC transporter permease
EPJLBGNC_01185 9.6e-78 glnP P ABC transporter permease
EPJLBGNC_01186 1.1e-181 steT E amino acid
EPJLBGNC_01187 3.8e-21 K Acetyltransferase (GNAT) domain
EPJLBGNC_01189 1.2e-164 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EPJLBGNC_01190 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
EPJLBGNC_01191 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EPJLBGNC_01192 1e-100 rplD J Forms part of the polypeptide exit tunnel
EPJLBGNC_01193 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EPJLBGNC_01194 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EPJLBGNC_01195 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EPJLBGNC_01196 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EPJLBGNC_01197 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EPJLBGNC_01198 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EPJLBGNC_01199 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
EPJLBGNC_01200 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EPJLBGNC_01201 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EPJLBGNC_01202 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EPJLBGNC_01203 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EPJLBGNC_01204 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPJLBGNC_01205 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EPJLBGNC_01206 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EPJLBGNC_01207 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EPJLBGNC_01208 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EPJLBGNC_01209 2.1e-22 rpmD J Ribosomal protein L30
EPJLBGNC_01210 1e-67 rplO J Binds to the 23S rRNA
EPJLBGNC_01211 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EPJLBGNC_01212 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EPJLBGNC_01213 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EPJLBGNC_01214 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EPJLBGNC_01215 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EPJLBGNC_01216 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EPJLBGNC_01217 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPJLBGNC_01218 4.8e-53 rplQ J Ribosomal protein L17
EPJLBGNC_01219 4e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPJLBGNC_01220 1.5e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPJLBGNC_01221 3.7e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPJLBGNC_01222 5.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EPJLBGNC_01223 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EPJLBGNC_01224 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
EPJLBGNC_01225 1.4e-30
EPJLBGNC_01226 1.2e-245 yjbQ P TrkA C-terminal domain protein
EPJLBGNC_01227 0.0 helD 3.6.4.12 L DNA helicase
EPJLBGNC_01228 2.3e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
EPJLBGNC_01229 9.6e-112 hrtB V ABC transporter permease
EPJLBGNC_01230 4.6e-35 ygfC K Bacterial regulatory proteins, tetR family
EPJLBGNC_01231 3.3e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EPJLBGNC_01232 2.5e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EPJLBGNC_01233 4.6e-36 M LysM domain protein
EPJLBGNC_01234 8.9e-116 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EPJLBGNC_01235 3.5e-101 sbcC L Putative exonuclease SbcCD, C subunit
EPJLBGNC_01236 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
EPJLBGNC_01237 7.2e-53 perR P Belongs to the Fur family
EPJLBGNC_01238 2.9e-208 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EPJLBGNC_01239 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPJLBGNC_01240 2.5e-86 S (CBS) domain
EPJLBGNC_01241 3.6e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EPJLBGNC_01242 5.5e-74 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EPJLBGNC_01243 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EPJLBGNC_01244 6.6e-141 yabM S Polysaccharide biosynthesis protein
EPJLBGNC_01245 3.6e-31 yabO J S4 domain protein
EPJLBGNC_01246 1e-21 divIC D Septum formation initiator
EPJLBGNC_01247 1.1e-40 yabR J RNA binding
EPJLBGNC_01248 3.6e-95 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EPJLBGNC_01249 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EPJLBGNC_01250 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EPJLBGNC_01251 2e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EPJLBGNC_01252 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPJLBGNC_01253 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EPJLBGNC_01254 8e-112 K IrrE N-terminal-like domain
EPJLBGNC_01255 4.1e-18
EPJLBGNC_01256 7.2e-38 L hmm pf00665
EPJLBGNC_01257 1.8e-49 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
EPJLBGNC_01258 1.1e-50 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
EPJLBGNC_01259 3.4e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EPJLBGNC_01260 3.9e-133 coaA 2.7.1.33 F Pantothenic acid kinase
EPJLBGNC_01261 1.7e-44 E GDSL-like Lipase/Acylhydrolase
EPJLBGNC_01262 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EPJLBGNC_01263 1.6e-189 glnPH2 P ABC transporter permease
EPJLBGNC_01264 2.1e-213 yjeM E Amino Acid
EPJLBGNC_01265 3.9e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
EPJLBGNC_01266 2.5e-137 tetA EGP Major facilitator Superfamily
EPJLBGNC_01267 1.3e-62 S Glycosyltransferase like family 2
EPJLBGNC_01268 1.5e-117 cps1D M Domain of unknown function (DUF4422)
EPJLBGNC_01269 4.3e-38 S CAAX protease self-immunity
EPJLBGNC_01270 9.1e-89 yvyE 3.4.13.9 S YigZ family
EPJLBGNC_01271 2.3e-58 S Haloacid dehalogenase-like hydrolase
EPJLBGNC_01272 4.5e-154 EGP Major facilitator Superfamily
EPJLBGNC_01274 1.5e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
EPJLBGNC_01275 2.1e-27 yraB K transcriptional regulator
EPJLBGNC_01276 2.9e-89 S NADPH-dependent FMN reductase
EPJLBGNC_01277 8.8e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EPJLBGNC_01278 1.5e-55 S ECF transporter, substrate-specific component
EPJLBGNC_01279 2.8e-103 znuB U ABC 3 transport family
EPJLBGNC_01280 6.5e-98 fhuC P ABC transporter
EPJLBGNC_01281 3.9e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
EPJLBGNC_01282 1.5e-38
EPJLBGNC_01283 7.3e-14 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
EPJLBGNC_01284 4.2e-53 XK27_01040 S Protein of unknown function (DUF1129)
EPJLBGNC_01285 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EPJLBGNC_01286 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
EPJLBGNC_01287 9.1e-108 spo0J K Belongs to the ParB family
EPJLBGNC_01288 5.5e-117 soj D Sporulation initiation inhibitor
EPJLBGNC_01289 9.5e-68 noc K Belongs to the ParB family
EPJLBGNC_01290 8.1e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
EPJLBGNC_01291 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EPJLBGNC_01292 2.4e-109 3.1.4.46 C phosphodiesterase
EPJLBGNC_01293 0.0 pacL 3.6.3.8 P P-type ATPase
EPJLBGNC_01294 6.1e-43 yvdD 3.2.2.10 S Possible lysine decarboxylase
EPJLBGNC_01295 1.4e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
EPJLBGNC_01297 5.2e-63 srtA 3.4.22.70 M sortase family
EPJLBGNC_01298 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EPJLBGNC_01299 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
EPJLBGNC_01300 3.7e-34
EPJLBGNC_01301 4.5e-140 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPJLBGNC_01302 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EPJLBGNC_01303 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EPJLBGNC_01304 1.1e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
EPJLBGNC_01305 1.1e-39 ybjQ S Belongs to the UPF0145 family
EPJLBGNC_01306 5.7e-08
EPJLBGNC_01307 1.8e-95 V ABC transporter, ATP-binding protein
EPJLBGNC_01308 1.1e-41 gntR1 K Transcriptional regulator, GntR family
EPJLBGNC_01309 1.4e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
EPJLBGNC_01310 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPJLBGNC_01311 3.2e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
EPJLBGNC_01312 2.2e-107 terC P Integral membrane protein TerC family
EPJLBGNC_01313 5.5e-39 K Transcriptional regulator
EPJLBGNC_01314 7.5e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
EPJLBGNC_01315 2e-100 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EPJLBGNC_01316 4.5e-102 tcyB E ABC transporter
EPJLBGNC_01317 1.1e-301 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EPJLBGNC_01318 3.4e-209 mtlR K Mga helix-turn-helix domain
EPJLBGNC_01319 3.7e-176 yjcE P Sodium proton antiporter
EPJLBGNC_01320 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
EPJLBGNC_01321 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
EPJLBGNC_01322 3.3e-69 dhaL 2.7.1.121 S Dak2
EPJLBGNC_01323 7.6e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
EPJLBGNC_01324 1.1e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
EPJLBGNC_01325 1.7e-61 K Bacterial regulatory proteins, tetR family
EPJLBGNC_01326 1.2e-207 brnQ U Component of the transport system for branched-chain amino acids
EPJLBGNC_01328 7.7e-109 endA F DNA RNA non-specific endonuclease
EPJLBGNC_01329 7e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
EPJLBGNC_01330 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
EPJLBGNC_01331 6.8e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
EPJLBGNC_01332 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
EPJLBGNC_01333 1.8e-57 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
EPJLBGNC_01334 5.1e-77 azlC E branched-chain amino acid
EPJLBGNC_01335 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
EPJLBGNC_01336 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
EPJLBGNC_01337 1.6e-55 jag S R3H domain protein
EPJLBGNC_01338 2.2e-125 sip L Belongs to the 'phage' integrase family
EPJLBGNC_01340 2e-34 K Helix-turn-helix XRE-family like proteins
EPJLBGNC_01342 3.6e-20 K Transcriptional regulator
EPJLBGNC_01343 3e-07
EPJLBGNC_01349 1.8e-46 L DNA replication protein
EPJLBGNC_01350 6.5e-133 S D5 N terminal like
EPJLBGNC_01352 1.4e-16
EPJLBGNC_01354 4.5e-53 K Transcriptional regulator C-terminal region
EPJLBGNC_01355 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
EPJLBGNC_01356 2e-285 pepO 3.4.24.71 O Peptidase family M13
EPJLBGNC_01357 5e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
EPJLBGNC_01358 2.1e-07 yvaZ S SdpI/YhfL protein family
EPJLBGNC_01359 8.6e-71 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
EPJLBGNC_01360 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
EPJLBGNC_01361 1.3e-40 wecD K Acetyltransferase GNAT Family
EPJLBGNC_01363 1.3e-37 aguA_2 3.5.3.12 E Porphyromonas-type peptidyl-arginine deiminase
EPJLBGNC_01364 6.3e-85 XK27_06780 V ABC transporter permease
EPJLBGNC_01365 3.4e-148 XK27_06780 V ABC transporter permease
EPJLBGNC_01366 7.1e-95 XK27_06785 V ABC transporter, ATP-binding protein
EPJLBGNC_01367 3.2e-34 tetR K transcriptional regulator
EPJLBGNC_01368 1.6e-15
EPJLBGNC_01370 1.1e-70 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPJLBGNC_01371 8.4e-119 ytbE S reductase
EPJLBGNC_01372 4.2e-43 ytcD K HxlR-like helix-turn-helix
EPJLBGNC_01373 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
EPJLBGNC_01374 2.6e-67 ybbL S ABC transporter
EPJLBGNC_01375 6.2e-163 oxlT P Major Facilitator Superfamily
EPJLBGNC_01376 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EPJLBGNC_01377 4.1e-47 S Short repeat of unknown function (DUF308)
EPJLBGNC_01378 3e-30 tetR K Transcriptional regulator C-terminal region
EPJLBGNC_01379 1.2e-150 yfeX P Peroxidase
EPJLBGNC_01380 6.6e-17 S Protein of unknown function (DUF3021)
EPJLBGNC_01381 4.5e-39 K LytTr DNA-binding domain
EPJLBGNC_01382 9e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
EPJLBGNC_01383 2.4e-208 mmuP E amino acid
EPJLBGNC_01384 9.2e-16 psiE S Phosphate-starvation-inducible E
EPJLBGNC_01385 2.2e-155 oppF P Belongs to the ABC transporter superfamily
EPJLBGNC_01386 1.3e-180 oppD P Belongs to the ABC transporter superfamily
EPJLBGNC_01387 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPJLBGNC_01388 4.6e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPJLBGNC_01389 4.7e-203 oppA E ABC transporter, substratebinding protein
EPJLBGNC_01390 2.3e-217 yifK E Amino acid permease
EPJLBGNC_01391 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EPJLBGNC_01392 3.9e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
EPJLBGNC_01393 1.4e-65 pgm3 G phosphoglycerate mutase family
EPJLBGNC_01394 2.1e-250 ctpA 3.6.3.54 P P-type ATPase
EPJLBGNC_01395 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
EPJLBGNC_01396 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
EPJLBGNC_01397 2.8e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EPJLBGNC_01398 1.2e-21 K transcriptional regulator
EPJLBGNC_01399 5e-77 hchA S intracellular protease amidase
EPJLBGNC_01400 1.3e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
EPJLBGNC_01401 1.8e-112 lacI3 K helix_turn _helix lactose operon repressor
EPJLBGNC_01402 4.2e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
EPJLBGNC_01403 7.5e-39 2.7.1.191 G PTS system fructose IIA component
EPJLBGNC_01404 7.1e-123 G PTS system mannose/fructose/sorbose family IID component
EPJLBGNC_01405 7.8e-90 G PTS system sorbose-specific iic component
EPJLBGNC_01406 5.8e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
EPJLBGNC_01407 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
EPJLBGNC_01408 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EPJLBGNC_01409 9.9e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
EPJLBGNC_01410 1.9e-116 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
EPJLBGNC_01411 9e-198 1.3.5.4 C FMN_bind
EPJLBGNC_01412 1.7e-56 3.1.3.48 K Transcriptional regulator
EPJLBGNC_01413 7.1e-160 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
EPJLBGNC_01414 5.3e-197 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
EPJLBGNC_01415 4.9e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
EPJLBGNC_01416 1.1e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
EPJLBGNC_01417 3.5e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EPJLBGNC_01418 2.5e-82 S Belongs to the UPF0246 family
EPJLBGNC_01419 1.9e-10 S CAAX protease self-immunity
EPJLBGNC_01420 1.6e-59 ykhA 3.1.2.20 I Thioesterase superfamily
EPJLBGNC_01421 1.5e-156 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EPJLBGNC_01423 9.6e-231 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EPJLBGNC_01424 4e-64 C FMN binding
EPJLBGNC_01425 3.6e-207 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EPJLBGNC_01426 1.7e-54 rplI J Binds to the 23S rRNA
EPJLBGNC_01427 3.9e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EPJLBGNC_01428 6.1e-07
EPJLBGNC_01432 3.5e-23 L PLD-like domain
EPJLBGNC_01433 6.5e-12 L PLD-like domain
EPJLBGNC_01435 6.1e-08 yokH G regulation of fungal-type cell wall biogenesis
EPJLBGNC_01436 9.4e-109 L Initiator Replication protein
EPJLBGNC_01437 1.9e-37 S Replication initiator protein A (RepA) N-terminus
EPJLBGNC_01438 8.5e-141 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EPJLBGNC_01439 1.4e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
EPJLBGNC_01440 1.4e-12 bglG K antiterminator
EPJLBGNC_01441 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
EPJLBGNC_01443 1.1e-35
EPJLBGNC_01444 0.0 pepN 3.4.11.2 E aminopeptidase
EPJLBGNC_01445 1.8e-43 2.7.13.3 T protein histidine kinase activity
EPJLBGNC_01446 1.6e-22 agrA KT Response regulator of the LytR AlgR family
EPJLBGNC_01448 1.3e-16 M domain protein
EPJLBGNC_01454 4.4e-123 yvgN C Aldo keto reductase
EPJLBGNC_01455 2.2e-70 K DeoR C terminal sensor domain
EPJLBGNC_01456 1.1e-46 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EPJLBGNC_01457 6.9e-42 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
EPJLBGNC_01458 1.2e-216 pts36C G PTS system sugar-specific permease component
EPJLBGNC_01460 2.3e-104 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
EPJLBGNC_01462 5.4e-58 S COG NOG19168 non supervised orthologous group
EPJLBGNC_01463 4.9e-190 XK27_11280 S Psort location CytoplasmicMembrane, score
EPJLBGNC_01464 7.1e-15 L Plasmid pRiA4b ORF-3-like protein
EPJLBGNC_01465 2.6e-105 L Belongs to the 'phage' integrase family
EPJLBGNC_01466 5.6e-18 3.1.21.3 V Type I restriction modification DNA specificity domain
EPJLBGNC_01467 6.6e-60 hsdM 2.1.1.72 V type I restriction-modification system
EPJLBGNC_01469 5e-125 L T/G mismatch-specific endonuclease activity
EPJLBGNC_01473 6.5e-217 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EPJLBGNC_01474 1.5e-46
EPJLBGNC_01475 2.8e-37
EPJLBGNC_01476 5e-11
EPJLBGNC_01477 6.9e-60 yeeA V Type II restriction enzyme, methylase subunits
EPJLBGNC_01478 1.8e-14 yeeA V Type II restriction enzyme, methylase subunits
EPJLBGNC_01479 1.9e-217 yeeA V Type II restriction enzyme, methylase subunits
EPJLBGNC_01480 2.4e-257 yeeB L DEAD-like helicases superfamily
EPJLBGNC_01481 1.5e-92 pstS P T5orf172
EPJLBGNC_01482 4.6e-15
EPJLBGNC_01484 4.6e-24
EPJLBGNC_01487 1.3e-161 potE2 E amino acid
EPJLBGNC_01488 1.1e-145 ald 1.4.1.1 C Belongs to the AlaDH PNT family
EPJLBGNC_01489 2.7e-116 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EPJLBGNC_01490 1.9e-57 racA K Domain of unknown function (DUF1836)
EPJLBGNC_01491 3.5e-80 yitS S EDD domain protein, DegV family
EPJLBGNC_01492 4.2e-45 yjaB_1 K Acetyltransferase (GNAT) domain
EPJLBGNC_01493 3.4e-07
EPJLBGNC_01494 7e-286 hsdR 3.1.21.3 L DEAD/DEAH box helicase
EPJLBGNC_01495 4e-225 hsdM 2.1.1.72 V type I restriction-modification system
EPJLBGNC_01496 8.6e-90 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
EPJLBGNC_01497 4.1e-67
EPJLBGNC_01498 1.8e-116 O AAA domain (Cdc48 subfamily)
EPJLBGNC_01499 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EPJLBGNC_01500 0.0 O Belongs to the peptidase S8 family
EPJLBGNC_01501 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
EPJLBGNC_01502 2.5e-58 tlpA2 L Transposase IS200 like
EPJLBGNC_01503 1.1e-157 L transposase, IS605 OrfB family
EPJLBGNC_01504 4.6e-84 dps P Ferritin-like domain
EPJLBGNC_01505 1.1e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
EPJLBGNC_01506 1.1e-42 L hmm pf00665
EPJLBGNC_01507 5e-18 tnp
EPJLBGNC_01508 8.7e-31 tnp L Transposase IS66 family
EPJLBGNC_01509 1.7e-32 P Heavy-metal-associated domain
EPJLBGNC_01510 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
EPJLBGNC_01511 1.3e-20 L PFAM transposase IS3 IS911 family protein
EPJLBGNC_01512 1.4e-41 L Integrase core domain
EPJLBGNC_01513 2.4e-35 L Integrase core domain
EPJLBGNC_01514 2.6e-129 EGP Major Facilitator Superfamily
EPJLBGNC_01515 4.1e-98 EGP Major Facilitator Superfamily
EPJLBGNC_01516 3.7e-72 K Transcriptional regulator, LysR family
EPJLBGNC_01517 4.7e-138 G Xylose isomerase-like TIM barrel
EPJLBGNC_01518 5e-116 IQ Enoyl-(Acyl carrier protein) reductase
EPJLBGNC_01519 1.6e-217 1.3.5.4 C FAD binding domain
EPJLBGNC_01520 6.5e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EPJLBGNC_01521 2e-71 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EPJLBGNC_01522 1.1e-142 xerS L Phage integrase family
EPJLBGNC_01523 1.4e-32 S Domain of unknown function (DUF4417)
EPJLBGNC_01528 3.4e-103 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
EPJLBGNC_01529 8.2e-13 ptp3 3.1.3.48 T Tyrosine phosphatase family
EPJLBGNC_01530 6.4e-29 ptp3 3.1.3.48 T Tyrosine phosphatase family
EPJLBGNC_01531 2.4e-75 desR K helix_turn_helix, Lux Regulon
EPJLBGNC_01532 1.2e-56 salK 2.7.13.3 T Histidine kinase
EPJLBGNC_01533 1.2e-52 yvfS V ABC-2 type transporter
EPJLBGNC_01534 5.2e-79 yvfR V ABC transporter
EPJLBGNC_01535 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EPJLBGNC_01536 1.7e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EPJLBGNC_01537 2.7e-30
EPJLBGNC_01538 8.2e-16
EPJLBGNC_01539 4.7e-112 rssA S Phospholipase, patatin family
EPJLBGNC_01540 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPJLBGNC_01541 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
EPJLBGNC_01542 7.2e-45 S VIT family
EPJLBGNC_01543 9.4e-240 sufB O assembly protein SufB
EPJLBGNC_01544 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
EPJLBGNC_01545 3.1e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EPJLBGNC_01546 1.1e-143 sufD O FeS assembly protein SufD
EPJLBGNC_01547 4e-115 sufC O FeS assembly ATPase SufC
EPJLBGNC_01548 1.4e-223 E ABC transporter, substratebinding protein
EPJLBGNC_01549 5.3e-24 S protein encoded in hypervariable junctions of pilus gene clusters
EPJLBGNC_01550 1.6e-26 K Helix-turn-helix XRE-family like proteins
EPJLBGNC_01551 7.3e-136 pfoS S Phosphotransferase system, EIIC
EPJLBGNC_01552 2.5e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
EPJLBGNC_01553 2.8e-64 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
EPJLBGNC_01554 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
EPJLBGNC_01555 2.7e-135 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
EPJLBGNC_01556 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
EPJLBGNC_01557 4.5e-43 gutM K Glucitol operon activator protein (GutM)
EPJLBGNC_01558 1.7e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
EPJLBGNC_01559 5.2e-110 IQ NAD dependent epimerase/dehydratase family
EPJLBGNC_01560 1e-26 M by MetaGeneAnnotator
EPJLBGNC_01561 1.7e-52 M Phage tail tape measure protein TP901
EPJLBGNC_01569 1.1e-21 S Phage minor capsid protein 2
EPJLBGNC_01570 3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
EPJLBGNC_01571 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EPJLBGNC_01574 9.2e-32 tonB M YSIRK type signal peptide
EPJLBGNC_01576 9.1e-265 fbp 3.1.3.11 G phosphatase activity
EPJLBGNC_01577 2.9e-71 xerD L Phage integrase, N-terminal SAM-like domain
EPJLBGNC_01580 1e-87 S Haloacid dehalogenase-like hydrolase
EPJLBGNC_01581 2.7e-15
EPJLBGNC_01583 5.9e-187 mtnE 2.6.1.83 E Aminotransferase
EPJLBGNC_01584 1.7e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
EPJLBGNC_01585 1.3e-66 S Protein of unknown function (DUF1440)
EPJLBGNC_01586 7.7e-41 S Iron-sulfur cluster assembly protein
EPJLBGNC_01587 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
EPJLBGNC_01588 1.1e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
EPJLBGNC_01589 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPJLBGNC_01590 9.6e-153 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EPJLBGNC_01591 4e-64 G Xylose isomerase domain protein TIM barrel
EPJLBGNC_01592 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
EPJLBGNC_01593 6.5e-90 nanK GK ROK family
EPJLBGNC_01594 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
EPJLBGNC_01595 2.5e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EPJLBGNC_01596 4.3e-75 K Helix-turn-helix domain, rpiR family
EPJLBGNC_01597 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
EPJLBGNC_01598 4.5e-216 yjeM E Amino Acid
EPJLBGNC_01600 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPJLBGNC_01601 3.1e-233 tetP J elongation factor G
EPJLBGNC_01603 1.1e-09 tcdC
EPJLBGNC_01605 7.3e-102 L PLD-like domain
EPJLBGNC_01610 3.8e-146 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EPJLBGNC_01611 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EPJLBGNC_01612 1.1e-278 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EPJLBGNC_01613 3.5e-160 camS S sex pheromone
EPJLBGNC_01614 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPJLBGNC_01615 1.8e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EPJLBGNC_01616 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPJLBGNC_01617 3.4e-146 yegS 2.7.1.107 G Lipid kinase
EPJLBGNC_01618 1.8e-211 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPJLBGNC_01619 2.4e-82
EPJLBGNC_01620 2.6e-44 yjdF S Protein of unknown function (DUF2992)
EPJLBGNC_01622 5.5e-196 L Recombinase
EPJLBGNC_01623 7.1e-15 S Recombinase
EPJLBGNC_01624 1.9e-116 L Recombinase zinc beta ribbon domain
EPJLBGNC_01626 2.9e-51 S Bacteriophage holin family
EPJLBGNC_01627 5.6e-46 S Phage head-tail joining protein
EPJLBGNC_01628 7.1e-30 S Phage gp6-like head-tail connector protein
EPJLBGNC_01629 6.6e-170 S Phage capsid family
EPJLBGNC_01630 3.2e-81 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
EPJLBGNC_01631 2.6e-217 S Phage portal protein
EPJLBGNC_01632 2.8e-11 K Antidote-toxin recognition MazE, bacterial antitoxin
EPJLBGNC_01634 2.5e-289 S overlaps another CDS with the same product name
EPJLBGNC_01635 1.1e-24 S Domain of unknown function (DUF5049)
EPJLBGNC_01636 2.7e-53 S Psort location Cytoplasmic, score
EPJLBGNC_01637 2.9e-200 2.1.1.72 KL DNA methylase
EPJLBGNC_01638 5.7e-92
EPJLBGNC_01639 4.6e-56 V HNH nucleases
EPJLBGNC_01640 2.1e-50
EPJLBGNC_01641 6.7e-198 L SNF2 family N-terminal domain
EPJLBGNC_01642 2.8e-32 S VRR_NUC
EPJLBGNC_01643 0.0 S Phage plasmid primase, P4
EPJLBGNC_01644 1.1e-39 S Psort location Cytoplasmic, score
EPJLBGNC_01645 1e-300 polA_2 2.7.7.7 L DNA polymerase
EPJLBGNC_01646 5e-88 S Protein of unknown function (DUF2815)
EPJLBGNC_01647 5.3e-143 L Protein of unknown function (DUF2800)
EPJLBGNC_01649 1.9e-08
EPJLBGNC_01651 2.9e-25
EPJLBGNC_01652 3.5e-15
EPJLBGNC_01653 2.9e-76 L AAA domain
EPJLBGNC_01654 4.8e-20 K Cro/C1-type HTH DNA-binding domain
EPJLBGNC_01655 1.7e-86 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
EPJLBGNC_01656 1.3e-113 2.1.1.72, 3.1.21.4 L site-specific DNA-methyltransferase (adenine-specific) activity
EPJLBGNC_01657 0.0 L Type III restriction enzyme, res subunit
EPJLBGNC_01658 0.0 S Protein of unknown function DUF262
EPJLBGNC_01661 1.2e-52 L Resolvase, N terminal domain
EPJLBGNC_01662 2.1e-48 L COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
EPJLBGNC_01663 0.0 3.1.11.5 L Psort location Cytoplasmic, score 8.87
EPJLBGNC_01664 5.1e-24
EPJLBGNC_01665 4.4e-34 3.1.21.3 V Type I restriction modification DNA specificity domain
EPJLBGNC_01667 2.6e-56 S UPF0489 domain
EPJLBGNC_01668 1.9e-121 L Mrr N-terminal domain
EPJLBGNC_01669 1.6e-14
EPJLBGNC_01670 5.7e-09
EPJLBGNC_01671 3.2e-74 S Domain of unknown function (DUF4343)
EPJLBGNC_01672 1.5e-57 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
EPJLBGNC_01673 1.2e-74 S Domain of unknown function (DUF3841)
EPJLBGNC_01674 8.1e-228 yfjM S Protein of unknown function DUF262
EPJLBGNC_01675 6.6e-176 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
EPJLBGNC_01676 2.8e-157 C Oxidoreductase
EPJLBGNC_01677 1.1e-71 ywlG S Belongs to the UPF0340 family
EPJLBGNC_01678 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EPJLBGNC_01679 1.6e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPJLBGNC_01680 1.5e-57 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EPJLBGNC_01681 8.2e-177 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
EPJLBGNC_01682 1.5e-14 ybaN S Protein of unknown function (DUF454)
EPJLBGNC_01683 1.3e-236 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EPJLBGNC_01684 1.4e-198 frdC 1.3.5.4 C FAD binding domain
EPJLBGNC_01685 1.1e-206 yflS P Sodium:sulfate symporter transmembrane region
EPJLBGNC_01686 4.4e-18 yncA 2.3.1.79 S Maltose acetyltransferase
EPJLBGNC_01687 8.2e-160 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPJLBGNC_01688 1.5e-61 dedA 3.1.3.1 S SNARE associated Golgi protein
EPJLBGNC_01689 4.2e-95 ypuA S Protein of unknown function (DUF1002)
EPJLBGNC_01690 2.6e-23 fhaB M Rib/alpha-like repeat
EPJLBGNC_01691 3.4e-07 fhaB M translation initiation factor activity
EPJLBGNC_01692 1.5e-42 K Copper transport repressor CopY TcrY
EPJLBGNC_01693 8e-60 T Belongs to the universal stress protein A family
EPJLBGNC_01694 1.3e-40 K Bacterial regulatory proteins, tetR family
EPJLBGNC_01695 3.6e-57 K transcriptional
EPJLBGNC_01696 2.4e-71 mleR K LysR family
EPJLBGNC_01697 5.8e-249 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
EPJLBGNC_01698 1.6e-13 mleP S Sodium Bile acid symporter family
EPJLBGNC_01699 1.6e-63 S ECF transporter, substrate-specific component
EPJLBGNC_01700 1.6e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
EPJLBGNC_01701 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EPJLBGNC_01702 1.7e-193 pbuX F xanthine permease
EPJLBGNC_01703 3e-37 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
EPJLBGNC_01704 3.4e-254 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
EPJLBGNC_01705 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
EPJLBGNC_01706 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EPJLBGNC_01707 7.6e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
EPJLBGNC_01708 9.4e-160 mgtE P Acts as a magnesium transporter
EPJLBGNC_01710 1.7e-40
EPJLBGNC_01711 2e-16 XK27_09675 K Acetyltransferase (GNAT) domain
EPJLBGNC_01712 3.8e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
EPJLBGNC_01713 4.6e-220 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
EPJLBGNC_01714 2.2e-42 O ADP-ribosylglycohydrolase
EPJLBGNC_01715 4.2e-221 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
EPJLBGNC_01716 6.2e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EPJLBGNC_01717 1.1e-156 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EPJLBGNC_01718 4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
EPJLBGNC_01719 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
EPJLBGNC_01720 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EPJLBGNC_01721 1.5e-176 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
EPJLBGNC_01722 3.4e-24 S Domain of unknown function (DUF4828)
EPJLBGNC_01723 5.4e-128 mocA S Oxidoreductase
EPJLBGNC_01724 3.9e-160 yfmL L DEAD DEAH box helicase
EPJLBGNC_01725 2e-20 S Domain of unknown function (DUF3284)
EPJLBGNC_01727 1.3e-279 kup P Transport of potassium into the cell
EPJLBGNC_01728 1.2e-100 malR K Transcriptional regulator, LacI family
EPJLBGNC_01729 3.8e-214 malT G Transporter, major facilitator family protein
EPJLBGNC_01730 7.7e-79 galM 5.1.3.3 G Aldose 1-epimerase
EPJLBGNC_01731 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
EPJLBGNC_01732 7.8e-83 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
EPJLBGNC_01733 2.2e-264 E Amino acid permease
EPJLBGNC_01734 1.3e-181 pepS E Thermophilic metalloprotease (M29)
EPJLBGNC_01735 2.1e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EPJLBGNC_01736 1.1e-70 K Sugar-specific transcriptional regulator TrmB
EPJLBGNC_01737 6.4e-122 S Sulfite exporter TauE/SafE
EPJLBGNC_01738 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
EPJLBGNC_01739 0.0 S Bacterial membrane protein YfhO
EPJLBGNC_01740 8.7e-53 gtcA S Teichoic acid glycosylation protein
EPJLBGNC_01741 2.6e-53 fld C Flavodoxin
EPJLBGNC_01742 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
EPJLBGNC_01743 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EPJLBGNC_01744 6.2e-12 mltD CBM50 M Lysin motif
EPJLBGNC_01745 3.2e-92 yihY S Belongs to the UPF0761 family
EPJLBGNC_01746 3.2e-95 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
EPJLBGNC_01748 6.3e-54 S Protein of unknown function (DUF4256)
EPJLBGNC_01749 8.2e-127 metQ M Belongs to the nlpA lipoprotein family
EPJLBGNC_01750 2.4e-31 metI U ABC transporter permease
EPJLBGNC_01751 6.2e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EPJLBGNC_01753 1e-261 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
EPJLBGNC_01754 8.1e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
EPJLBGNC_01755 1e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
EPJLBGNC_01756 4.3e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
EPJLBGNC_01757 3e-84 drgA C nitroreductase
EPJLBGNC_01758 8.2e-133 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
EPJLBGNC_01759 1.3e-69 metI P ABC transporter permease
EPJLBGNC_01760 2.6e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EPJLBGNC_01761 1.8e-108 metQ1 P Belongs to the nlpA lipoprotein family
EPJLBGNC_01762 2e-144 2.1.1.14 E methionine synthase, vitamin-B12 independent
EPJLBGNC_01763 1e-45 yphJ 4.1.1.44 S decarboxylase
EPJLBGNC_01764 1.4e-58 yphH S Cupin domain
EPJLBGNC_01765 5.7e-48 C Flavodoxin
EPJLBGNC_01766 2.7e-56 S CAAX protease self-immunity
EPJLBGNC_01767 1.5e-102 pgm3 G phosphoglycerate mutase
EPJLBGNC_01768 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EPJLBGNC_01769 4.2e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EPJLBGNC_01770 1.4e-49 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EPJLBGNC_01771 4.4e-67 M ErfK YbiS YcfS YnhG
EPJLBGNC_01772 3.9e-107 XK27_08845 S ABC transporter, ATP-binding protein
EPJLBGNC_01773 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
EPJLBGNC_01774 5.1e-131 ABC-SBP S ABC transporter
EPJLBGNC_01775 1.7e-159 potD P ABC transporter
EPJLBGNC_01776 1.7e-103 potC U Binding-protein-dependent transport system inner membrane component
EPJLBGNC_01777 1.5e-120 potB P ABC transporter permease
EPJLBGNC_01778 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EPJLBGNC_01779 2.4e-98 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
EPJLBGNC_01780 2.2e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
EPJLBGNC_01781 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EPJLBGNC_01782 3.9e-13 S Enterocin A Immunity
EPJLBGNC_01784 2.2e-16 pspC KT PspC domain
EPJLBGNC_01785 4.1e-16 S Putative adhesin
EPJLBGNC_01786 4.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
EPJLBGNC_01787 1.3e-38 K transcriptional regulator PadR family
EPJLBGNC_01788 1.5e-46 S CRISPR-associated protein (Cas_Csn2)
EPJLBGNC_01789 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EPJLBGNC_01790 7.2e-108 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EPJLBGNC_01791 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EPJLBGNC_01792 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
EPJLBGNC_01793 3.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
EPJLBGNC_01794 4.9e-165 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPJLBGNC_01795 2e-81 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EPJLBGNC_01796 4e-40 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EPJLBGNC_01797 2.7e-70 mltD CBM50 M NlpC P60 family protein
EPJLBGNC_01798 3.2e-52 manO S Domain of unknown function (DUF956)
EPJLBGNC_01799 2.1e-147 manN G system, mannose fructose sorbose family IID component
EPJLBGNC_01800 6.4e-116 manY G PTS system sorbose-specific iic component
EPJLBGNC_01801 5.3e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
EPJLBGNC_01802 2.6e-79 rbsB G sugar-binding domain protein
EPJLBGNC_01803 1.2e-103 baeS T Histidine kinase
EPJLBGNC_01804 3e-79 baeR K Bacterial regulatory proteins, luxR family
EPJLBGNC_01805 2.6e-119 G Bacterial extracellular solute-binding protein
EPJLBGNC_01806 2.3e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPJLBGNC_01807 4.2e-32 merR K MerR HTH family regulatory protein
EPJLBGNC_01808 7.9e-197 lmrB EGP Major facilitator Superfamily
EPJLBGNC_01809 1.3e-32 S Domain of unknown function (DUF4811)
EPJLBGNC_01810 8.2e-84 G Phosphoglycerate mutase family
EPJLBGNC_01811 5e-60 yceE S haloacid dehalogenase-like hydrolase
EPJLBGNC_01812 8.4e-73 glcR K DeoR C terminal sensor domain
EPJLBGNC_01813 2.4e-93 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EPJLBGNC_01814 1.1e-182 lmrB EGP Major facilitator Superfamily
EPJLBGNC_01815 5.6e-282 fruA 3.2.1.1, 3.2.1.65, 3.2.1.80 GH13,GH32 GN Fructan beta-fructosidase
EPJLBGNC_01816 3.3e-52 bioY S BioY family
EPJLBGNC_01817 9.9e-93 S Predicted membrane protein (DUF2207)
EPJLBGNC_01818 1.4e-19
EPJLBGNC_01819 4e-38 M Glycosyltransferase like family 2
EPJLBGNC_01820 9.8e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
EPJLBGNC_01821 9.7e-59 ktrA P TrkA-N domain
EPJLBGNC_01822 1.2e-114 ntpJ P Potassium uptake protein
EPJLBGNC_01823 7.7e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
EPJLBGNC_01824 5.2e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
EPJLBGNC_01825 1.2e-216 scrB 3.2.1.26 GH32 G invertase
EPJLBGNC_01826 2.3e-147 scrR K helix_turn _helix lactose operon repressor
EPJLBGNC_01827 7.8e-136 S interspecies interaction between organisms
EPJLBGNC_01828 1.2e-207 G glycerol-3-phosphate transporter
EPJLBGNC_01829 5.8e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EPJLBGNC_01830 6.2e-145 htrA 3.4.21.107 O serine protease
EPJLBGNC_01831 2.2e-116 vicX 3.1.26.11 S domain protein
EPJLBGNC_01832 6.8e-30 yyaQ S YjbR
EPJLBGNC_01833 5.6e-80 yycI S YycH protein
EPJLBGNC_01834 7.9e-103 yycH S YycH protein
EPJLBGNC_01835 1.5e-272 vicK 2.7.13.3 T Histidine kinase
EPJLBGNC_01836 9e-114 K response regulator
EPJLBGNC_01837 6.1e-106 yxeH S hydrolase
EPJLBGNC_01838 1e-227 V ABC transporter transmembrane region
EPJLBGNC_01839 1.1e-216 XK27_09600 V ABC transporter, ATP-binding protein
EPJLBGNC_01840 7.1e-32 K Transcriptional regulator, MarR family
EPJLBGNC_01841 8.9e-174 S Putative peptidoglycan binding domain
EPJLBGNC_01842 3.8e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
EPJLBGNC_01843 1.1e-137 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
EPJLBGNC_01844 1.5e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EPJLBGNC_01845 3.1e-106 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EPJLBGNC_01846 4.5e-204 pepF E Oligopeptidase F
EPJLBGNC_01847 3.7e-96 yicL EG EamA-like transporter family
EPJLBGNC_01848 7e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
EPJLBGNC_01849 1.6e-167 yjjP S Putative threonine/serine exporter
EPJLBGNC_01850 1.7e-24 S PFAM Archaeal ATPase
EPJLBGNC_01851 3e-60 S PFAM Archaeal ATPase
EPJLBGNC_01852 2.7e-170 ydfJ EGP Sugar (and other) transporter
EPJLBGNC_01853 1.3e-137 rspB 1.1.1.380 C Zinc-binding dehydrogenase
EPJLBGNC_01854 1.5e-173 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
EPJLBGNC_01855 5.5e-207 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
EPJLBGNC_01856 1.5e-49 kdgR K FCD domain
EPJLBGNC_01857 1e-113 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
EPJLBGNC_01858 3.7e-61 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
EPJLBGNC_01859 4.8e-109 glcU U sugar transport
EPJLBGNC_01860 1e-14 yobS K transcriptional regulator
EPJLBGNC_01861 2e-153 mdtG EGP Major facilitator Superfamily
EPJLBGNC_01862 1.2e-105 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EPJLBGNC_01863 4.2e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
EPJLBGNC_01864 7.4e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPJLBGNC_01865 9.5e-18 yneR
EPJLBGNC_01866 4.8e-247 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EPJLBGNC_01867 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EPJLBGNC_01868 2.1e-60 yiiE S Protein of unknown function (DUF1211)
EPJLBGNC_01869 0.0 asnB 6.3.5.4 E Asparagine synthase
EPJLBGNC_01870 7.4e-64 D peptidase
EPJLBGNC_01871 7.3e-117 S Glycosyl transferase family 2
EPJLBGNC_01872 4.8e-109 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
EPJLBGNC_01873 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EPJLBGNC_01874 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EPJLBGNC_01875 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
EPJLBGNC_01876 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPJLBGNC_01877 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPJLBGNC_01878 1.2e-152 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EPJLBGNC_01879 9e-20 yaaA S S4 domain protein YaaA
EPJLBGNC_01880 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EPJLBGNC_01881 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EPJLBGNC_01882 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
EPJLBGNC_01883 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EPJLBGNC_01884 3.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EPJLBGNC_01885 1.1e-199 nupG F Nucleoside
EPJLBGNC_01886 1.3e-121 MA20_14895 S Conserved hypothetical protein 698
EPJLBGNC_01887 1.7e-53 K LysR substrate binding domain
EPJLBGNC_01888 9.6e-09
EPJLBGNC_01889 3.2e-67 yxkH G Polysaccharide deacetylase
EPJLBGNC_01890 9e-30 yqkB S Belongs to the HesB IscA family
EPJLBGNC_01891 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EPJLBGNC_01892 5.5e-243 lysP E amino acid
EPJLBGNC_01893 6.8e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
EPJLBGNC_01894 2.5e-271 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EPJLBGNC_01895 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPJLBGNC_01896 9.4e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
EPJLBGNC_01897 4.5e-83 lysR5 K LysR substrate binding domain
EPJLBGNC_01898 1.7e-119 yxaA S membrane transporter protein
EPJLBGNC_01899 2.6e-32 ywjH S Protein of unknown function (DUF1634)
EPJLBGNC_01900 4.3e-123 brpA K Cell envelope-like function transcriptional attenuator common domain protein
EPJLBGNC_01901 1.2e-223 pipD E Dipeptidase
EPJLBGNC_01902 7.5e-20 K helix_turn_helix multiple antibiotic resistance protein
EPJLBGNC_01903 2.1e-164 EGP Major facilitator Superfamily
EPJLBGNC_01904 5.6e-82 S L,D-transpeptidase catalytic domain
EPJLBGNC_01905 7.8e-141 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EPJLBGNC_01906 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EPJLBGNC_01907 7.2e-27 ydiI Q Thioesterase superfamily
EPJLBGNC_01908 4.7e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
EPJLBGNC_01909 9.6e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
EPJLBGNC_01910 1.9e-113 degV S EDD domain protein, DegV family
EPJLBGNC_01911 9.3e-232 cadA P P-type ATPase
EPJLBGNC_01912 5.3e-254 E Amino acid permease
EPJLBGNC_01913 6e-83 S Membrane
EPJLBGNC_01914 2e-49 cps3F
EPJLBGNC_01915 2.3e-300 fruA 2.7.1.202 GT Phosphotransferase System
EPJLBGNC_01916 4.5e-150 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EPJLBGNC_01917 2.2e-86 fruR K DeoR C terminal sensor domain
EPJLBGNC_01918 3e-219 XK27_08635 S UPF0210 protein
EPJLBGNC_01919 4.1e-27 gcvR T Belongs to the UPF0237 family
EPJLBGNC_01920 8.9e-38
EPJLBGNC_01921 1.4e-76 E GDSL-like Lipase/Acylhydrolase family
EPJLBGNC_01922 9.2e-56 S Protein of unknown function (DUF975)
EPJLBGNC_01923 1.2e-148 lplA 6.3.1.20 H Lipoate-protein ligase
EPJLBGNC_01924 1.5e-229 lpdA 1.8.1.4 C Dehydrogenase
EPJLBGNC_01925 9e-181 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EPJLBGNC_01926 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
EPJLBGNC_01927 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EPJLBGNC_01928 1.3e-06 M MucBP domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)