ORF_ID e_value Gene_name EC_number CAZy COGs Description
NPEIKGBL_00001 1.3e-252 gutA G MFS/sugar transport protein
NPEIKGBL_00002 2.7e-199 gutB 1.1.1.14 E Dehydrogenase
NPEIKGBL_00003 0.0 K NB-ARC domain
NPEIKGBL_00004 2e-151 ydjC S Abhydrolase domain containing 18
NPEIKGBL_00005 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPEIKGBL_00006 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPEIKGBL_00007 7.9e-129 ydiL S CAAX protease self-immunity
NPEIKGBL_00008 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NPEIKGBL_00009 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NPEIKGBL_00010 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NPEIKGBL_00011 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPEIKGBL_00012 7.2e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NPEIKGBL_00013 0.0 ydiF S ABC transporter
NPEIKGBL_00014 3e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPEIKGBL_00015 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NPEIKGBL_00016 2.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NPEIKGBL_00017 1.2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NPEIKGBL_00018 7.6e-180 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NPEIKGBL_00020 7.8e-08
NPEIKGBL_00021 3.4e-39 S COG NOG14552 non supervised orthologous group
NPEIKGBL_00024 2.3e-156 ydhU P Catalase
NPEIKGBL_00025 2.9e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NPEIKGBL_00026 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
NPEIKGBL_00027 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NPEIKGBL_00028 1.1e-132 ydhQ K UTRA
NPEIKGBL_00029 2.8e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPEIKGBL_00030 3.4e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEIKGBL_00031 5.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NPEIKGBL_00032 3.5e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NPEIKGBL_00033 4.6e-200 pbuE EGP Major facilitator Superfamily
NPEIKGBL_00034 9.4e-98 ydhK M Protein of unknown function (DUF1541)
NPEIKGBL_00035 1e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPEIKGBL_00036 8e-82 K Acetyltransferase (GNAT) domain
NPEIKGBL_00038 1.1e-67 frataxin S Domain of unknown function (DU1801)
NPEIKGBL_00039 6.9e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NPEIKGBL_00040 7.4e-124
NPEIKGBL_00041 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NPEIKGBL_00042 5.5e-231 ydhD M Glycosyl hydrolase
NPEIKGBL_00043 6.5e-122 ydhC K FCD
NPEIKGBL_00044 1.6e-121 ydhB S membrane transporter protein
NPEIKGBL_00045 3.1e-207 tcaB EGP Major facilitator Superfamily
NPEIKGBL_00046 2.4e-69 ydgJ K Winged helix DNA-binding domain
NPEIKGBL_00047 2.3e-113 drgA C nitroreductase
NPEIKGBL_00048 0.0 ydgH S drug exporters of the RND superfamily
NPEIKGBL_00049 1.8e-79 K helix_turn_helix multiple antibiotic resistance protein
NPEIKGBL_00050 1.3e-90 dinB S DinB family
NPEIKGBL_00051 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NPEIKGBL_00052 2.9e-301 expZ S ABC transporter
NPEIKGBL_00053 1.9e-83 yycN 2.3.1.128 K Acetyltransferase
NPEIKGBL_00054 1.5e-50 S DoxX-like family
NPEIKGBL_00055 6.7e-94 K Bacterial regulatory proteins, tetR family
NPEIKGBL_00056 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
NPEIKGBL_00057 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
NPEIKGBL_00058 1.1e-74 cotP O Belongs to the small heat shock protein (HSP20) family
NPEIKGBL_00059 7.6e-121 ydfS S Protein of unknown function (DUF421)
NPEIKGBL_00060 4.4e-118 ydfR S Protein of unknown function (DUF421)
NPEIKGBL_00062 6.3e-29
NPEIKGBL_00063 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NPEIKGBL_00064 7.7e-55 traF CO Thioredoxin
NPEIKGBL_00065 8.8e-63 mhqP S DoxX
NPEIKGBL_00066 6.2e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NPEIKGBL_00067 3.1e-110 ydfN C nitroreductase
NPEIKGBL_00068 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPEIKGBL_00069 9.2e-147 K Bacterial transcription activator, effector binding domain
NPEIKGBL_00070 2.5e-116 S Protein of unknown function (DUF554)
NPEIKGBL_00071 3.1e-175 S Alpha/beta hydrolase family
NPEIKGBL_00072 0.0 ydfJ S drug exporters of the RND superfamily
NPEIKGBL_00073 9.3e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEIKGBL_00074 1.8e-175 ydfH 2.7.13.3 T Histidine kinase
NPEIKGBL_00076 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NPEIKGBL_00077 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NPEIKGBL_00078 1.4e-115 ydfE S Flavin reductase like domain
NPEIKGBL_00079 6e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPEIKGBL_00080 6.3e-160 ydfC EG EamA-like transporter family
NPEIKGBL_00081 2e-146 ydfB J GNAT acetyltransferase
NPEIKGBL_00082 5.7e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NPEIKGBL_00083 1.8e-56 arsR K transcriptional
NPEIKGBL_00084 2.1e-103 ydeS K Transcriptional regulator
NPEIKGBL_00085 1.6e-184 ydeR EGP Major facilitator Superfamily
NPEIKGBL_00086 3.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
NPEIKGBL_00087 4.8e-69 ydeP K Transcriptional regulator
NPEIKGBL_00088 1.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NPEIKGBL_00089 2e-55 K HxlR-like helix-turn-helix
NPEIKGBL_00090 5.8e-103 ydeN S Serine hydrolase
NPEIKGBL_00091 6e-73 maoC I N-terminal half of MaoC dehydratase
NPEIKGBL_00092 1.7e-273 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPEIKGBL_00093 3.9e-151 ydeK EG -transporter
NPEIKGBL_00094 3.4e-84 K Transcriptional regulator C-terminal region
NPEIKGBL_00095 8.3e-15 ptsH G PTS HPr component phosphorylation site
NPEIKGBL_00096 1.1e-31 S SNARE associated Golgi protein
NPEIKGBL_00097 9.1e-100
NPEIKGBL_00098 6.2e-39 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NPEIKGBL_00099 1.3e-23 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NPEIKGBL_00100 2.7e-45 ydeH
NPEIKGBL_00101 1.3e-216 ydeG EGP Major facilitator superfamily
NPEIKGBL_00102 1.1e-261 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPEIKGBL_00103 1.7e-162 ydeE K AraC family transcriptional regulator
NPEIKGBL_00104 4.9e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NPEIKGBL_00105 1.2e-163 rhaS5 K AraC-like ligand binding domain
NPEIKGBL_00106 2.6e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NPEIKGBL_00107 3e-78 carD K Transcription factor
NPEIKGBL_00108 8.7e-30 cspL K Cold shock
NPEIKGBL_00109 1.3e-110 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NPEIKGBL_00113 1.9e-40
NPEIKGBL_00114 5.6e-34 K Helix-turn-helix XRE-family like proteins
NPEIKGBL_00116 8.5e-70 L HNH nucleases
NPEIKGBL_00117 9.6e-205 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NPEIKGBL_00118 1.1e-48 S SMI1-KNR4 cell-wall
NPEIKGBL_00119 1.5e-78 S FRG
NPEIKGBL_00121 8e-75 S response regulator aspartate phosphatase
NPEIKGBL_00122 3.1e-217 L Superfamily I DNA and RNA helicases
NPEIKGBL_00123 2e-228 L AAA ATPase domain
NPEIKGBL_00124 1.1e-38 S Domain of unknown function with cystatin-like fold (DUF4467)
NPEIKGBL_00125 9.1e-84 yddI
NPEIKGBL_00126 2.2e-187 yddH CBM50 M Lysozyme-like
NPEIKGBL_00127 0.0 yddG S maturation of SSU-rRNA
NPEIKGBL_00128 2.8e-54 S Domain of unknown function (DUF1874)
NPEIKGBL_00129 0.0 yddE S AAA-like domain
NPEIKGBL_00130 3.4e-94 yddD S TcpE family
NPEIKGBL_00131 3e-40 yddC
NPEIKGBL_00132 1.5e-165 yddB S Conjugative transposon protein TcpC
NPEIKGBL_00134 1.4e-39
NPEIKGBL_00135 6.7e-36 yddA
NPEIKGBL_00137 2.1e-199 nicK L Replication initiation factor
NPEIKGBL_00138 1.9e-248 ydcQ D Ftsk spoiiie family protein
NPEIKGBL_00139 6.2e-73
NPEIKGBL_00140 1.7e-63 S Bacterial protein of unknown function (DUF961)
NPEIKGBL_00142 2.5e-37
NPEIKGBL_00143 2e-20
NPEIKGBL_00144 6.8e-36 yvaO K Transcriptional
NPEIKGBL_00145 4.6e-18 immA E IrrE N-terminal-like domain
NPEIKGBL_00146 5.9e-120 L Phage integrase family
NPEIKGBL_00154 1.6e-84 ydcK S Belongs to the SprT family
NPEIKGBL_00155 0.0 yhgF K COG2183 Transcriptional accessory protein
NPEIKGBL_00156 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NPEIKGBL_00157 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEIKGBL_00158 3.2e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NPEIKGBL_00159 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
NPEIKGBL_00160 9.3e-189 rsbU 3.1.3.3 KT phosphatase
NPEIKGBL_00161 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NPEIKGBL_00162 5.2e-57 rsbS T antagonist
NPEIKGBL_00163 3.7e-143 rsbR T Positive regulator of sigma-B
NPEIKGBL_00164 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NPEIKGBL_00165 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NPEIKGBL_00166 3.7e-221 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPEIKGBL_00167 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NPEIKGBL_00168 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPEIKGBL_00169 4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NPEIKGBL_00170 3.9e-260 ydbT S Membrane
NPEIKGBL_00171 2.1e-82 ydbS S Bacterial PH domain
NPEIKGBL_00172 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPEIKGBL_00173 9.2e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPEIKGBL_00174 8.7e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NPEIKGBL_00175 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NPEIKGBL_00176 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPEIKGBL_00177 2.2e-07 S Fur-regulated basic protein A
NPEIKGBL_00178 1.1e-18 S Fur-regulated basic protein B
NPEIKGBL_00179 4.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NPEIKGBL_00180 2.7e-52 ydbL
NPEIKGBL_00181 1.2e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NPEIKGBL_00182 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
NPEIKGBL_00183 9.7e-181 ydbI S AI-2E family transporter
NPEIKGBL_00184 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPEIKGBL_00185 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
NPEIKGBL_00186 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NPEIKGBL_00187 3.5e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NPEIKGBL_00188 1e-153 ydbD P Catalase
NPEIKGBL_00189 1.8e-62 ydbC S Domain of unknown function (DUF4937
NPEIKGBL_00190 1.5e-33 ydbB G Cupin domain
NPEIKGBL_00192 1.1e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NPEIKGBL_00193 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NPEIKGBL_00195 1.7e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NPEIKGBL_00196 4.7e-39
NPEIKGBL_00197 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NPEIKGBL_00198 1.6e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NPEIKGBL_00199 0.0 ydaO E amino acid
NPEIKGBL_00200 0.0 ydaN S Bacterial cellulose synthase subunit
NPEIKGBL_00201 4.5e-233 ydaM M Glycosyl transferase family group 2
NPEIKGBL_00202 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NPEIKGBL_00203 4.2e-150 ydaK T Diguanylate cyclase, GGDEF domain
NPEIKGBL_00204 3.1e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NPEIKGBL_00205 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPEIKGBL_00206 2.5e-74 lrpC K Transcriptional regulator
NPEIKGBL_00207 3.3e-46 ydzA EGP Major facilitator Superfamily
NPEIKGBL_00208 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NPEIKGBL_00209 6.8e-77 ydaG 1.4.3.5 S general stress protein
NPEIKGBL_00210 4.7e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NPEIKGBL_00211 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NPEIKGBL_00212 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEIKGBL_00213 9e-99 ydaC Q Methyltransferase domain
NPEIKGBL_00214 1.8e-292 ydaB IQ acyl-CoA ligase
NPEIKGBL_00215 0.0 mtlR K transcriptional regulator, MtlR
NPEIKGBL_00216 5.8e-174 ydhF S Oxidoreductase
NPEIKGBL_00217 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NPEIKGBL_00218 8e-47 yczJ S biosynthesis
NPEIKGBL_00220 1.3e-119 ycsK E anatomical structure formation involved in morphogenesis
NPEIKGBL_00221 2.7e-132 kipR K Transcriptional regulator
NPEIKGBL_00222 3.3e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NPEIKGBL_00223 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NPEIKGBL_00224 1.1e-147 ycsI S Belongs to the D-glutamate cyclase family
NPEIKGBL_00225 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NPEIKGBL_00226 2.3e-139 ycsF S Belongs to the UPF0271 (lamB) family
NPEIKGBL_00227 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NPEIKGBL_00229 1e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NPEIKGBL_00230 4.8e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NPEIKGBL_00231 4.2e-98 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NPEIKGBL_00232 7.2e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NPEIKGBL_00233 2.8e-210 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NPEIKGBL_00234 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NPEIKGBL_00235 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NPEIKGBL_00236 7.3e-56
NPEIKGBL_00237 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NPEIKGBL_00238 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
NPEIKGBL_00239 1.4e-99 ycnI S protein conserved in bacteria
NPEIKGBL_00240 6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEIKGBL_00241 6.1e-149 glcU U Glucose uptake
NPEIKGBL_00242 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPEIKGBL_00243 5.3e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPEIKGBL_00244 5.1e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPEIKGBL_00245 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NPEIKGBL_00246 1.6e-45 ycnE S Monooxygenase
NPEIKGBL_00247 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NPEIKGBL_00248 7.1e-153 ycnC K Transcriptional regulator
NPEIKGBL_00249 3.2e-251 ycnB EGP Major facilitator Superfamily
NPEIKGBL_00250 2.7e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NPEIKGBL_00251 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NPEIKGBL_00252 9.7e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEIKGBL_00253 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEIKGBL_00254 1.7e-246 lysC 2.7.2.4 E Belongs to the aspartokinase family
NPEIKGBL_00258 2e-70 S aspartate phosphatase
NPEIKGBL_00259 4.4e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NPEIKGBL_00260 4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEIKGBL_00261 6.2e-202 yclI V ABC transporter (permease) YclI
NPEIKGBL_00262 1.6e-120 yclH P ABC transporter
NPEIKGBL_00263 6.4e-199 gerKB F Spore germination protein
NPEIKGBL_00264 1.3e-232 gerKC S spore germination
NPEIKGBL_00265 1.6e-278 gerKA EG Spore germination protein
NPEIKGBL_00267 1.6e-308 yclG M Pectate lyase superfamily protein
NPEIKGBL_00268 6.2e-266 dtpT E amino acid peptide transporter
NPEIKGBL_00269 1.4e-153 yclE 3.4.11.5 S Alpha beta hydrolase
NPEIKGBL_00270 1.6e-79 yclD
NPEIKGBL_00271 4e-39 bsdD 4.1.1.61 S response to toxic substance
NPEIKGBL_00272 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NPEIKGBL_00273 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NPEIKGBL_00274 1.9e-161 bsdA K LysR substrate binding domain
NPEIKGBL_00275 2.9e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NPEIKGBL_00276 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NPEIKGBL_00277 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NPEIKGBL_00278 1.7e-114 yczE S membrane
NPEIKGBL_00279 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NPEIKGBL_00280 2.1e-252 ycxD K GntR family transcriptional regulator
NPEIKGBL_00281 5.8e-161 ycxC EG EamA-like transporter family
NPEIKGBL_00282 3.2e-90 S YcxB-like protein
NPEIKGBL_00283 6.1e-227 EGP Major Facilitator Superfamily
NPEIKGBL_00284 1.3e-139 srfAD Q thioesterase
NPEIKGBL_00285 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NPEIKGBL_00286 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEIKGBL_00287 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEIKGBL_00288 1.3e-63 hxlR K transcriptional
NPEIKGBL_00289 1.2e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NPEIKGBL_00290 3e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NPEIKGBL_00291 5.6e-186 tlpC 2.7.13.3 NT chemotaxis protein
NPEIKGBL_00292 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
NPEIKGBL_00293 1.2e-67 nin S Competence protein J (ComJ)
NPEIKGBL_00294 1.2e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPEIKGBL_00295 7.8e-52 yckD S Protein of unknown function (DUF2680)
NPEIKGBL_00296 8.2e-76 yckC S membrane
NPEIKGBL_00298 2.6e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NPEIKGBL_00299 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
NPEIKGBL_00300 7e-228 yciC S GTPases (G3E family)
NPEIKGBL_00301 7.9e-108 yciB M ErfK YbiS YcfS YnhG
NPEIKGBL_00302 1.5e-169 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NPEIKGBL_00303 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
NPEIKGBL_00304 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NPEIKGBL_00305 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPEIKGBL_00306 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NPEIKGBL_00307 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NPEIKGBL_00308 1.3e-276 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NPEIKGBL_00309 6e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NPEIKGBL_00310 4e-156 I alpha/beta hydrolase fold
NPEIKGBL_00311 6.5e-138 ycgR S permeases
NPEIKGBL_00312 2.6e-147 ycgQ S membrane
NPEIKGBL_00313 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NPEIKGBL_00314 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPEIKGBL_00315 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NPEIKGBL_00316 5.1e-170 ycgM E Proline dehydrogenase
NPEIKGBL_00317 2.4e-144 ycgL S Predicted nucleotidyltransferase
NPEIKGBL_00318 4.2e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NPEIKGBL_00319 3.2e-178 oxyR3 K LysR substrate binding domain
NPEIKGBL_00320 3.1e-144 yafE Q ubiE/COQ5 methyltransferase family
NPEIKGBL_00321 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NPEIKGBL_00322 6.8e-107 tmrB S AAA domain
NPEIKGBL_00323 4.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPEIKGBL_00324 2.4e-112 ycgI S Domain of unknown function (DUF1989)
NPEIKGBL_00325 2.1e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NPEIKGBL_00326 1.2e-151 yqcI S YqcI/YcgG family
NPEIKGBL_00327 6.8e-113 ycgF E Lysine exporter protein LysE YggA
NPEIKGBL_00328 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
NPEIKGBL_00329 1.1e-268 mdr EGP Major facilitator Superfamily
NPEIKGBL_00330 2e-289 lctP C L-lactate permease
NPEIKGBL_00331 1.2e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPEIKGBL_00332 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NPEIKGBL_00333 4.1e-81 ycgB
NPEIKGBL_00334 5.6e-256 ycgA S Membrane
NPEIKGBL_00335 1.4e-217 amhX S amidohydrolase
NPEIKGBL_00336 5.3e-164 opuAC E glycine betaine
NPEIKGBL_00337 1.3e-127 opuAB P glycine betaine
NPEIKGBL_00338 2.5e-228 proV 3.6.3.32 E glycine betaine
NPEIKGBL_00339 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NPEIKGBL_00340 5.7e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
NPEIKGBL_00341 1.5e-217 naiP P Uncharacterised MFS-type transporter YbfB
NPEIKGBL_00342 2e-192 yceH P Belongs to the TelA family
NPEIKGBL_00343 0.0 yceG S Putative component of 'biosynthetic module'
NPEIKGBL_00344 1.4e-136 terC P Protein of unknown function (DUF475)
NPEIKGBL_00345 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
NPEIKGBL_00346 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NPEIKGBL_00347 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NPEIKGBL_00348 1.5e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPEIKGBL_00349 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NPEIKGBL_00350 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NPEIKGBL_00351 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
NPEIKGBL_00352 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NPEIKGBL_00353 1.8e-139 IQ Enoyl-(Acyl carrier protein) reductase
NPEIKGBL_00354 1.2e-173 S response regulator aspartate phosphatase
NPEIKGBL_00355 1.1e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
NPEIKGBL_00356 2.5e-267 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NPEIKGBL_00357 2.4e-275 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NPEIKGBL_00358 6.6e-177 ycdA S Domain of unknown function (DUF5105)
NPEIKGBL_00359 1.7e-173 yccK C Aldo keto reductase
NPEIKGBL_00360 1.6e-200 natB CP ABC-2 family transporter protein
NPEIKGBL_00361 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NPEIKGBL_00362 1.2e-126 lytR_2 T LytTr DNA-binding domain
NPEIKGBL_00363 6.1e-158 2.7.13.3 T GHKL domain
NPEIKGBL_00364 8.1e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
NPEIKGBL_00365 3.4e-59 S RDD family
NPEIKGBL_00366 2.1e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NPEIKGBL_00367 2e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NPEIKGBL_00368 1.6e-100 yxaF K Transcriptional regulator
NPEIKGBL_00369 5.8e-229 lmrB EGP the major facilitator superfamily
NPEIKGBL_00370 6.2e-210 ycbU E Selenocysteine lyase
NPEIKGBL_00371 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NPEIKGBL_00372 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NPEIKGBL_00373 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NPEIKGBL_00374 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NPEIKGBL_00375 2.5e-135 ycbR T vWA found in TerF C terminus
NPEIKGBL_00376 1.3e-78 sleB 3.5.1.28 M Cell wall
NPEIKGBL_00377 8.2e-53 ycbP S Protein of unknown function (DUF2512)
NPEIKGBL_00378 2.1e-115 S ABC-2 family transporter protein
NPEIKGBL_00379 1.4e-167 ycbN V ABC transporter, ATP-binding protein
NPEIKGBL_00380 4.2e-167 T PhoQ Sensor
NPEIKGBL_00381 2.2e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEIKGBL_00382 1.2e-166 eamA1 EG spore germination
NPEIKGBL_00383 5.7e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NPEIKGBL_00384 7e-175 ycbJ S Macrolide 2'-phosphotransferase
NPEIKGBL_00385 9.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
NPEIKGBL_00386 1.5e-124 ycbG K FCD
NPEIKGBL_00387 1.8e-267 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NPEIKGBL_00388 4.5e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NPEIKGBL_00389 3.4e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPEIKGBL_00390 7.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NPEIKGBL_00391 2.6e-169 glnL T Regulator
NPEIKGBL_00392 9.4e-229 phoQ 2.7.13.3 T Histidine kinase
NPEIKGBL_00393 1.3e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
NPEIKGBL_00394 3.3e-256 agcS E Sodium alanine symporter
NPEIKGBL_00395 6.7e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NPEIKGBL_00396 3.1e-259 mmuP E amino acid
NPEIKGBL_00397 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NPEIKGBL_00399 1.9e-127 K UTRA
NPEIKGBL_00400 1e-136 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPEIKGBL_00401 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPEIKGBL_00402 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPEIKGBL_00403 8.6e-192 yceA S Belongs to the UPF0176 family
NPEIKGBL_00404 6.7e-167 ybfP K Transcriptional regulator
NPEIKGBL_00405 1.1e-253 S Erythromycin esterase
NPEIKGBL_00406 1.6e-45 ybfN
NPEIKGBL_00407 3.1e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NPEIKGBL_00408 2.7e-85 ybfM S SNARE associated Golgi protein
NPEIKGBL_00409 3.5e-94 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPEIKGBL_00410 1.4e-164 S Alpha/beta hydrolase family
NPEIKGBL_00412 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NPEIKGBL_00413 2.6e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NPEIKGBL_00414 3.3e-144 msmR K AraC-like ligand binding domain
NPEIKGBL_00415 6.9e-159 ybfH EG EamA-like transporter family
NPEIKGBL_00416 0.0 ybfG M Domain of unknown function (DUF1906)
NPEIKGBL_00418 5.5e-223 ybfB G COG0477 Permeases of the major facilitator superfamily
NPEIKGBL_00419 2.6e-169 ybfA 3.4.15.5 K FR47-like protein
NPEIKGBL_00420 1.5e-34 S Protein of unknown function (DUF2651)
NPEIKGBL_00421 7.3e-258 glpT G -transporter
NPEIKGBL_00422 3.7e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NPEIKGBL_00423 1.8e-290 ybeC E amino acid
NPEIKGBL_00424 4.9e-41 ybyB
NPEIKGBL_00425 2.3e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NPEIKGBL_00426 6.9e-80 ybxI 3.5.2.6 V beta-lactamase
NPEIKGBL_00427 5.9e-35 ybxI 3.5.2.6 V beta-lactamase
NPEIKGBL_00428 4.9e-30 ybxH S Family of unknown function (DUF5370)
NPEIKGBL_00429 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
NPEIKGBL_00430 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NPEIKGBL_00431 4.2e-217 ybdO S Domain of unknown function (DUF4885)
NPEIKGBL_00432 5.3e-153 ybdN
NPEIKGBL_00433 4.7e-140 KLT Protein tyrosine kinase
NPEIKGBL_00435 1.8e-173 T His Kinase A (phospho-acceptor) domain
NPEIKGBL_00436 1.5e-123 T Transcriptional regulatory protein, C terminal
NPEIKGBL_00437 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NPEIKGBL_00438 9.6e-79 txn CO Thioredoxin-like
NPEIKGBL_00439 7.8e-91 C HEAT repeats
NPEIKGBL_00440 7.6e-247 skfF S ABC transporter
NPEIKGBL_00441 9.7e-132 skfE V ABC transporter
NPEIKGBL_00442 5.1e-276 V CAAX protease self-immunity
NPEIKGBL_00443 9.1e-239 J 4Fe-4S single cluster domain
NPEIKGBL_00445 2.2e-202 ybcL EGP Major facilitator Superfamily
NPEIKGBL_00446 5.1e-50 ybzH K Helix-turn-helix domain
NPEIKGBL_00448 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
NPEIKGBL_00449 1.9e-46
NPEIKGBL_00450 2.1e-91 can 4.2.1.1 P carbonic anhydrase
NPEIKGBL_00451 0.0 ybcC S Belongs to the UPF0753 family
NPEIKGBL_00452 9.7e-275 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NPEIKGBL_00453 4.3e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NPEIKGBL_00454 5.8e-120 adaA 3.2.2.21 K Transcriptional regulator
NPEIKGBL_00455 1.6e-171 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NPEIKGBL_00456 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPEIKGBL_00457 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPEIKGBL_00458 1.5e-224 ybbR S protein conserved in bacteria
NPEIKGBL_00459 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPEIKGBL_00460 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NPEIKGBL_00461 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NPEIKGBL_00467 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NPEIKGBL_00468 1.9e-86 ybbJ J acetyltransferase
NPEIKGBL_00469 6.7e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NPEIKGBL_00470 3.2e-150 ybbH K transcriptional
NPEIKGBL_00471 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPEIKGBL_00472 2.7e-252 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NPEIKGBL_00473 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NPEIKGBL_00474 3.2e-239 ybbC 3.2.1.52 S protein conserved in bacteria
NPEIKGBL_00475 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NPEIKGBL_00476 1.4e-165 feuA P Iron-uptake system-binding protein
NPEIKGBL_00477 2.4e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEIKGBL_00478 1.9e-178 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEIKGBL_00479 1.9e-138 ybbA S Putative esterase
NPEIKGBL_00480 1e-160 ybaS 1.1.1.58 S Na -dependent transporter
NPEIKGBL_00482 1.8e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NPEIKGBL_00484 3.4e-39 S COG NOG14552 non supervised orthologous group
NPEIKGBL_00485 3.4e-39 S COG NOG14552 non supervised orthologous group
NPEIKGBL_00489 2e-08
NPEIKGBL_00492 3.4e-39 S COG NOG14552 non supervised orthologous group
NPEIKGBL_00493 1e-139 pdaB 3.5.1.104 G Polysaccharide deacetylase
NPEIKGBL_00494 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NPEIKGBL_00495 1.2e-84 gerD
NPEIKGBL_00496 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NPEIKGBL_00497 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NPEIKGBL_00498 2.8e-65 ybaK S Protein of unknown function (DUF2521)
NPEIKGBL_00499 2.4e-144 ybaJ Q Methyltransferase domain
NPEIKGBL_00500 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NPEIKGBL_00501 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPEIKGBL_00502 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPEIKGBL_00503 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPEIKGBL_00504 3.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPEIKGBL_00505 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPEIKGBL_00506 3.6e-58 rplQ J Ribosomal protein L17
NPEIKGBL_00507 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPEIKGBL_00508 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPEIKGBL_00509 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPEIKGBL_00510 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NPEIKGBL_00511 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPEIKGBL_00512 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NPEIKGBL_00513 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPEIKGBL_00514 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPEIKGBL_00515 1.8e-72 rplO J binds to the 23S rRNA
NPEIKGBL_00516 1.9e-23 rpmD J Ribosomal protein L30
NPEIKGBL_00517 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPEIKGBL_00518 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPEIKGBL_00519 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPEIKGBL_00520 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPEIKGBL_00521 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPEIKGBL_00522 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPEIKGBL_00523 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPEIKGBL_00524 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPEIKGBL_00525 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPEIKGBL_00526 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NPEIKGBL_00527 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPEIKGBL_00528 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPEIKGBL_00529 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPEIKGBL_00530 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPEIKGBL_00531 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPEIKGBL_00532 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPEIKGBL_00533 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
NPEIKGBL_00534 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPEIKGBL_00535 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NPEIKGBL_00536 2.6e-185 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NPEIKGBL_00537 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPEIKGBL_00538 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPEIKGBL_00539 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPEIKGBL_00540 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPEIKGBL_00541 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NPEIKGBL_00542 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPEIKGBL_00543 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPEIKGBL_00544 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
NPEIKGBL_00545 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPEIKGBL_00546 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPEIKGBL_00547 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPEIKGBL_00548 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPEIKGBL_00549 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NPEIKGBL_00550 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NPEIKGBL_00551 4.4e-115 sigH K Belongs to the sigma-70 factor family
NPEIKGBL_00552 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NPEIKGBL_00553 9.8e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPEIKGBL_00554 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPEIKGBL_00555 5.5e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPEIKGBL_00556 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
NPEIKGBL_00557 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPEIKGBL_00558 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NPEIKGBL_00559 9.4e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NPEIKGBL_00560 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NPEIKGBL_00561 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NPEIKGBL_00562 2.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPEIKGBL_00563 0.0 clpC O Belongs to the ClpA ClpB family
NPEIKGBL_00564 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NPEIKGBL_00565 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NPEIKGBL_00566 2.9e-76 ctsR K Belongs to the CtsR family
NPEIKGBL_00567 3.4e-39 S COG NOG14552 non supervised orthologous group
NPEIKGBL_00572 2e-08
NPEIKGBL_00577 3.4e-39 S COG NOG14552 non supervised orthologous group
NPEIKGBL_00578 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NPEIKGBL_00579 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPEIKGBL_00580 4.1e-30 yazB K transcriptional
NPEIKGBL_00581 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NPEIKGBL_00582 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NPEIKGBL_00583 8.5e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NPEIKGBL_00584 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NPEIKGBL_00585 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NPEIKGBL_00586 1.8e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NPEIKGBL_00587 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NPEIKGBL_00588 4.4e-135 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NPEIKGBL_00589 1.9e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPEIKGBL_00590 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NPEIKGBL_00591 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPEIKGBL_00592 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NPEIKGBL_00593 3.8e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPEIKGBL_00594 6.1e-180 KLT serine threonine protein kinase
NPEIKGBL_00595 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NPEIKGBL_00596 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NPEIKGBL_00599 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NPEIKGBL_00600 1.1e-44 divIC D Septum formation initiator
NPEIKGBL_00601 9.5e-107 yabQ S spore cortex biosynthesis protein
NPEIKGBL_00602 1.5e-49 yabP S Sporulation protein YabP
NPEIKGBL_00603 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NPEIKGBL_00604 7.8e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NPEIKGBL_00605 4.9e-285 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPEIKGBL_00606 1.5e-92 spoVT K stage V sporulation protein
NPEIKGBL_00607 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPEIKGBL_00608 2.4e-39 yabK S Peptide ABC transporter permease
NPEIKGBL_00609 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPEIKGBL_00610 7.3e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NPEIKGBL_00611 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPEIKGBL_00612 9.5e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPEIKGBL_00613 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NPEIKGBL_00614 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NPEIKGBL_00615 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NPEIKGBL_00616 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NPEIKGBL_00617 7.8e-39 veg S protein conserved in bacteria
NPEIKGBL_00618 2.8e-136 yabG S peptidase
NPEIKGBL_00619 6.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPEIKGBL_00620 3e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPEIKGBL_00621 2e-167 rpfB GH23 T protein conserved in bacteria
NPEIKGBL_00622 1.2e-143 tatD L hydrolase, TatD
NPEIKGBL_00623 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPEIKGBL_00624 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NPEIKGBL_00625 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPEIKGBL_00626 1.5e-49 yazA L endonuclease containing a URI domain
NPEIKGBL_00627 5.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
NPEIKGBL_00628 4.8e-31 yabA L Involved in initiation control of chromosome replication
NPEIKGBL_00629 6.1e-146 yaaT S stage 0 sporulation protein
NPEIKGBL_00630 1.1e-181 holB 2.7.7.7 L DNA polymerase III
NPEIKGBL_00631 1.5e-71 yaaR S protein conserved in bacteria
NPEIKGBL_00632 2.2e-54 yaaQ S protein conserved in bacteria
NPEIKGBL_00633 5.3e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPEIKGBL_00634 6.6e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NPEIKGBL_00635 4.5e-203 yaaN P Belongs to the TelA family
NPEIKGBL_00636 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NPEIKGBL_00637 3.4e-31 csfB S Inhibitor of sigma-G Gin
NPEIKGBL_00640 3.4e-39 S COG NOG14552 non supervised orthologous group
NPEIKGBL_00641 1.8e-35 bofA S Sigma-K factor-processing regulatory protein BofA
NPEIKGBL_00642 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NPEIKGBL_00643 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPEIKGBL_00644 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPEIKGBL_00645 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPEIKGBL_00646 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPEIKGBL_00647 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
NPEIKGBL_00648 2.4e-213 yaaH M Glycoside Hydrolase Family
NPEIKGBL_00649 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NPEIKGBL_00650 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NPEIKGBL_00651 1.3e-09
NPEIKGBL_00652 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPEIKGBL_00653 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NPEIKGBL_00654 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NPEIKGBL_00655 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NPEIKGBL_00656 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NPEIKGBL_00657 3.9e-181 yaaC S YaaC-like Protein
NPEIKGBL_00660 3.4e-39 S COG NOG14552 non supervised orthologous group
NPEIKGBL_00661 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPEIKGBL_00662 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPEIKGBL_00663 1.8e-37 yaaB S Domain of unknown function (DUF370)
NPEIKGBL_00664 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPEIKGBL_00665 2.4e-33 yaaA S S4 domain
NPEIKGBL_00666 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPEIKGBL_00667 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPEIKGBL_00668 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPEIKGBL_00669 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPEIKGBL_00670 6.5e-108 jag S single-stranded nucleic acid binding R3H
NPEIKGBL_00671 1.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPEIKGBL_00672 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPEIKGBL_00673 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NPEIKGBL_00674 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NPEIKGBL_00675 2.1e-73 S Bacterial PH domain
NPEIKGBL_00676 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NPEIKGBL_00677 2.1e-149 spo0J K Belongs to the ParB family
NPEIKGBL_00678 2.8e-111 yyaC S Sporulation protein YyaC
NPEIKGBL_00679 8.1e-177 yyaD S Membrane
NPEIKGBL_00680 2.3e-33 yyzM S protein conserved in bacteria
NPEIKGBL_00681 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPEIKGBL_00682 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPEIKGBL_00683 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NPEIKGBL_00684 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPEIKGBL_00685 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPEIKGBL_00686 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
NPEIKGBL_00687 1.2e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NPEIKGBL_00688 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEIKGBL_00689 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NPEIKGBL_00690 2.3e-243 EGP Major facilitator superfamily
NPEIKGBL_00691 3.4e-166 yyaK S CAAX protease self-immunity
NPEIKGBL_00692 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NPEIKGBL_00693 2.9e-84 E Transglutaminase-like superfamily
NPEIKGBL_00694 5.2e-53 arsR K ArsR family transcriptional regulator
NPEIKGBL_00695 3.7e-67 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEIKGBL_00696 1.3e-151 arsB 1.20.4.1 P Arsenic resistance protein
NPEIKGBL_00697 6.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
NPEIKGBL_00698 2.2e-137 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NPEIKGBL_00699 8.4e-38 ydeP K HxlR-like helix-turn-helix
NPEIKGBL_00700 7.6e-27 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NPEIKGBL_00701 4.1e-248 tetL EGP Major facilitator Superfamily
NPEIKGBL_00702 3.6e-105 yyaP 1.5.1.3 H RibD C-terminal domain
NPEIKGBL_00703 6.6e-65 yyaQ S YjbR
NPEIKGBL_00704 2.1e-91 yyaR K Acetyltransferase (GNAT) domain
NPEIKGBL_00705 5e-97 yyaS S Membrane
NPEIKGBL_00706 2e-71 yjcF S Acetyltransferase (GNAT) domain
NPEIKGBL_00707 5.6e-77 yybA 2.3.1.57 K transcriptional
NPEIKGBL_00708 6.6e-127 S Metallo-beta-lactamase superfamily
NPEIKGBL_00709 6.6e-76 yybC
NPEIKGBL_00710 1.4e-77 yjcF S Acetyltransferase (GNAT) domain
NPEIKGBL_00711 6.9e-164 yybE K Transcriptional regulator
NPEIKGBL_00712 4.3e-217 ynfM EGP Major facilitator Superfamily
NPEIKGBL_00713 4.8e-122 yybG S Pentapeptide repeat-containing protein
NPEIKGBL_00714 1e-66 yybH S SnoaL-like domain
NPEIKGBL_00715 6.9e-123
NPEIKGBL_00716 4.3e-111 K TipAS antibiotic-recognition domain
NPEIKGBL_00717 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NPEIKGBL_00719 1.6e-60
NPEIKGBL_00720 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NPEIKGBL_00721 1.7e-66 ydeP3 K Transcriptional regulator
NPEIKGBL_00722 3.9e-84 cotF M Spore coat protein
NPEIKGBL_00724 8.3e-160 yybS S membrane
NPEIKGBL_00725 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NPEIKGBL_00726 2.2e-73 rplI J binds to the 23S rRNA
NPEIKGBL_00727 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPEIKGBL_00728 8.4e-221 yeaN P COG2807 Cyanate permease
NPEIKGBL_00729 1.9e-15 yycC K YycC-like protein
NPEIKGBL_00731 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NPEIKGBL_00732 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NPEIKGBL_00733 4.4e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEIKGBL_00734 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPEIKGBL_00739 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEIKGBL_00740 0.0 vicK 2.7.13.3 T Histidine kinase
NPEIKGBL_00741 9.8e-258 yycH S protein conserved in bacteria
NPEIKGBL_00742 5.2e-153 yycI S protein conserved in bacteria
NPEIKGBL_00743 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NPEIKGBL_00744 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPEIKGBL_00745 1.9e-33 S Peptidase propeptide and YPEB domain
NPEIKGBL_00746 9.8e-73 S Peptidase propeptide and YPEB domain
NPEIKGBL_00747 3.4e-94 K PFAM response regulator receiver
NPEIKGBL_00748 2.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
NPEIKGBL_00749 4.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NPEIKGBL_00750 1e-39 sdpR K transcriptional
NPEIKGBL_00751 1.5e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NPEIKGBL_00752 2.3e-24 S Sporulation delaying protein SdpA
NPEIKGBL_00753 1.3e-94
NPEIKGBL_00754 7.4e-16
NPEIKGBL_00755 3.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NPEIKGBL_00756 9.7e-261 rocE E amino acid
NPEIKGBL_00757 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NPEIKGBL_00759 4.2e-187 S aspartate phosphatase
NPEIKGBL_00760 1.2e-82 yycN 2.3.1.128 K Acetyltransferase
NPEIKGBL_00761 1.3e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NPEIKGBL_00762 1.9e-206 yycP
NPEIKGBL_00763 1.7e-30 yycQ S Protein of unknown function (DUF2651)
NPEIKGBL_00765 6.7e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NPEIKGBL_00766 1.2e-65
NPEIKGBL_00767 1.1e-09 S YyzF-like protein
NPEIKGBL_00768 9.8e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPEIKGBL_00769 9.5e-101 O ATPase family associated with various cellular activities (AAA)
NPEIKGBL_00770 5.8e-251 O Subtilase family
NPEIKGBL_00771 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NPEIKGBL_00772 5.4e-110 prrC P ABC transporter
NPEIKGBL_00773 3.3e-119 S ABC-2 family transporter protein
NPEIKGBL_00774 7.6e-13
NPEIKGBL_00775 1.1e-124 yydK K Transcriptional regulator
NPEIKGBL_00776 1.8e-31 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
NPEIKGBL_00777 2.7e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPEIKGBL_00778 2.8e-188 wgaE S Polysaccharide pyruvyl transferase
NPEIKGBL_00779 1.9e-286 ahpF O Alkyl hydroperoxide reductase
NPEIKGBL_00780 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NPEIKGBL_00781 5.5e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPEIKGBL_00782 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
NPEIKGBL_00783 1.1e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NPEIKGBL_00784 7.3e-127 gntR K transcriptional
NPEIKGBL_00785 9.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NPEIKGBL_00786 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
NPEIKGBL_00787 2.6e-118 yxaC M effector of murein hydrolase
NPEIKGBL_00788 7.6e-49 S LrgA family
NPEIKGBL_00789 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NPEIKGBL_00790 1.2e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEIKGBL_00791 1.3e-99 yxaF K Transcriptional regulator
NPEIKGBL_00792 1.9e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
NPEIKGBL_00793 5.6e-225 P Protein of unknown function (DUF418)
NPEIKGBL_00794 1.4e-75 yxaI S membrane protein domain
NPEIKGBL_00795 1.8e-61 S Family of unknown function (DUF5391)
NPEIKGBL_00796 6.8e-93 S PQQ-like domain
NPEIKGBL_00797 3.8e-22 yxaI S membrane protein domain
NPEIKGBL_00799 6.4e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NPEIKGBL_00800 1.1e-206 yxbF K Bacterial regulatory proteins, tetR family
NPEIKGBL_00801 3.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
NPEIKGBL_00803 0.0 htpG O Molecular chaperone. Has ATPase activity
NPEIKGBL_00804 1.1e-245 csbC EGP Major facilitator Superfamily
NPEIKGBL_00805 8.3e-48 yxcD S Protein of unknown function (DUF2653)
NPEIKGBL_00807 8.3e-176 iolS C Aldo keto reductase
NPEIKGBL_00808 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NPEIKGBL_00809 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPEIKGBL_00810 3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NPEIKGBL_00811 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NPEIKGBL_00812 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NPEIKGBL_00813 2.3e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NPEIKGBL_00814 4.7e-233 iolF EGP Major facilitator Superfamily
NPEIKGBL_00815 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NPEIKGBL_00816 8.6e-167 iolH G Xylose isomerase-like TIM barrel
NPEIKGBL_00817 1.6e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NPEIKGBL_00818 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NPEIKGBL_00819 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEIKGBL_00820 1.1e-178 T PhoQ Sensor
NPEIKGBL_00821 7.5e-138 yxdL V ABC transporter, ATP-binding protein
NPEIKGBL_00822 0.0 yxdM V ABC transporter (permease)
NPEIKGBL_00823 1.5e-58 yxeA S Protein of unknown function (DUF1093)
NPEIKGBL_00824 3.9e-176 fhuD P ABC transporter
NPEIKGBL_00825 5.5e-68
NPEIKGBL_00826 1.6e-15 yxeD
NPEIKGBL_00827 1.2e-16 yxeE
NPEIKGBL_00830 1.8e-150 yidA S hydrolases of the HAD superfamily
NPEIKGBL_00831 1.4e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NPEIKGBL_00832 2.7e-252 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPEIKGBL_00833 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEIKGBL_00834 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
NPEIKGBL_00835 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
NPEIKGBL_00836 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NPEIKGBL_00837 4.7e-213 yxeP 3.5.1.47 E hydrolase activity
NPEIKGBL_00838 2.1e-249 yxeQ S MmgE/PrpD family
NPEIKGBL_00839 3.2e-198 eutH E Ethanolamine utilisation protein, EutH
NPEIKGBL_00840 1.3e-151 yxxB S Domain of Unknown Function (DUF1206)
NPEIKGBL_00841 2.3e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NPEIKGBL_00842 4.5e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NPEIKGBL_00843 3.7e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NPEIKGBL_00844 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NPEIKGBL_00845 2.3e-251 lysP E amino acid
NPEIKGBL_00846 9.8e-180 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NPEIKGBL_00847 7.4e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NPEIKGBL_00848 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NPEIKGBL_00849 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
NPEIKGBL_00850 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NPEIKGBL_00851 5.1e-278 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NPEIKGBL_00852 4.3e-19 S Domain of unknown function (DUF5082)
NPEIKGBL_00853 1.4e-38 yxiC S Family of unknown function (DUF5344)
NPEIKGBL_00854 6.2e-217 S nuclease activity
NPEIKGBL_00855 1.8e-45
NPEIKGBL_00856 3.4e-27 S Uncharacterized protein conserved in bacteria (DUF2247)
NPEIKGBL_00857 9.9e-42
NPEIKGBL_00858 3.9e-27
NPEIKGBL_00859 5.5e-57
NPEIKGBL_00860 1.2e-40
NPEIKGBL_00861 4.4e-20
NPEIKGBL_00862 1.5e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPEIKGBL_00863 2.4e-278 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPEIKGBL_00864 9.2e-72 yxiE T Belongs to the universal stress protein A family
NPEIKGBL_00865 2.3e-165 yxxF EG EamA-like transporter family
NPEIKGBL_00866 0.0 wapA M COG3209 Rhs family protein
NPEIKGBL_00867 1.5e-71 yxxG
NPEIKGBL_00868 1.7e-84
NPEIKGBL_00869 6.4e-63
NPEIKGBL_00870 3.7e-75 yxiG
NPEIKGBL_00871 4.9e-46
NPEIKGBL_00872 3.8e-81
NPEIKGBL_00873 1.2e-96 yxiI S Protein of unknown function (DUF2716)
NPEIKGBL_00874 1.6e-48 yxiJ S YxiJ-like protein
NPEIKGBL_00877 2.3e-215 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NPEIKGBL_00878 1.1e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NPEIKGBL_00879 9.9e-228 yxiO S COG2270 Permeases of the major facilitator superfamily
NPEIKGBL_00880 6.2e-112
NPEIKGBL_00881 8.3e-151 licT K transcriptional antiterminator
NPEIKGBL_00882 7.3e-143 exoK GH16 M licheninase activity
NPEIKGBL_00883 1.5e-223 citH C Citrate transporter
NPEIKGBL_00884 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NPEIKGBL_00885 5.6e-46 yxiS
NPEIKGBL_00886 5.2e-103 T Domain of unknown function (DUF4163)
NPEIKGBL_00887 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NPEIKGBL_00888 2.2e-145 rlmA 2.1.1.187 Q Methyltransferase domain
NPEIKGBL_00889 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
NPEIKGBL_00890 3.1e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NPEIKGBL_00891 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NPEIKGBL_00892 2.4e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NPEIKGBL_00893 1.7e-218 yxjG 2.1.1.14 E Methionine synthase
NPEIKGBL_00894 6.7e-220 yxjG 2.1.1.14 E Methionine synthase
NPEIKGBL_00895 1.6e-85 yxjI S LURP-one-related
NPEIKGBL_00898 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NPEIKGBL_00899 4.9e-114 K helix_turn_helix, Lux Regulon
NPEIKGBL_00900 9.2e-191 yxjM T Signal transduction histidine kinase
NPEIKGBL_00901 5.9e-77 S Protein of unknown function (DUF1453)
NPEIKGBL_00902 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NPEIKGBL_00903 2.8e-74 yxkC S Domain of unknown function (DUF4352)
NPEIKGBL_00904 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPEIKGBL_00905 1.6e-274 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPEIKGBL_00906 2.7e-163 lrp QT PucR C-terminal helix-turn-helix domain
NPEIKGBL_00907 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NPEIKGBL_00908 1.6e-154 yxkH G Polysaccharide deacetylase
NPEIKGBL_00910 3.5e-310 3.4.24.84 O Peptidase family M48
NPEIKGBL_00911 1.5e-229 cimH C COG3493 Na citrate symporter
NPEIKGBL_00912 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
NPEIKGBL_00913 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NPEIKGBL_00914 1.1e-306 cydD V ATP-binding
NPEIKGBL_00915 0.0 cydD V ATP-binding protein
NPEIKGBL_00916 5.3e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPEIKGBL_00917 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NPEIKGBL_00918 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NPEIKGBL_00919 3.9e-48 yxlC S Family of unknown function (DUF5345)
NPEIKGBL_00920 1.4e-30
NPEIKGBL_00921 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
NPEIKGBL_00922 1.7e-165 yxlF V ABC transporter, ATP-binding protein
NPEIKGBL_00923 4.4e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NPEIKGBL_00924 2.6e-214 yxlH EGP Major facilitator Superfamily
NPEIKGBL_00925 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NPEIKGBL_00926 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NPEIKGBL_00927 1.1e-19 yxzF
NPEIKGBL_00928 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NPEIKGBL_00929 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NPEIKGBL_00930 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEIKGBL_00931 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NPEIKGBL_00932 2.4e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NPEIKGBL_00933 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NPEIKGBL_00934 2.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEIKGBL_00935 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPEIKGBL_00936 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEIKGBL_00937 1.2e-232 dltB M membrane protein involved in D-alanine export
NPEIKGBL_00938 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEIKGBL_00939 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NPEIKGBL_00940 2.5e-115 ywaC 2.7.6.5 S protein conserved in bacteria
NPEIKGBL_00941 4e-130 ynfM EGP Major facilitator Superfamily
NPEIKGBL_00942 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
NPEIKGBL_00943 1.4e-92 K Helix-turn-helix XRE-family like proteins
NPEIKGBL_00944 6.3e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NPEIKGBL_00945 1.3e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPEIKGBL_00946 4e-87 ywaE K Transcriptional regulator
NPEIKGBL_00947 2.3e-125 ywaF S Integral membrane protein
NPEIKGBL_00948 2.9e-167 gspA M General stress
NPEIKGBL_00949 1.2e-152 sacY K transcriptional antiterminator
NPEIKGBL_00950 7.6e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPEIKGBL_00951 8.9e-273 epr 3.4.21.62 O Belongs to the peptidase S8 family
NPEIKGBL_00952 2.8e-241 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPEIKGBL_00953 9.9e-67 ywbC 4.4.1.5 E glyoxalase
NPEIKGBL_00954 5.4e-220 ywbD 2.1.1.191 J Methyltransferase
NPEIKGBL_00955 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
NPEIKGBL_00956 9e-207 ywbF EGP Major facilitator Superfamily
NPEIKGBL_00957 2.3e-111 ywbG M effector of murein hydrolase
NPEIKGBL_00958 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NPEIKGBL_00959 4.3e-153 ywbI K Transcriptional regulator
NPEIKGBL_00960 8.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NPEIKGBL_00961 5.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NPEIKGBL_00962 3.8e-252 P COG0672 High-affinity Fe2 Pb2 permease
NPEIKGBL_00963 3.2e-185 ycdO P periplasmic lipoprotein involved in iron transport
NPEIKGBL_00964 7.9e-222 ywbN P Dyp-type peroxidase family protein
NPEIKGBL_00965 1.8e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NPEIKGBL_00966 4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPEIKGBL_00967 2.9e-48 ywcB S Protein of unknown function, DUF485
NPEIKGBL_00969 1.1e-121 ywcC K transcriptional regulator
NPEIKGBL_00970 1.4e-58 gtcA S GtrA-like protein
NPEIKGBL_00971 2.5e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPEIKGBL_00972 1e-300 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NPEIKGBL_00973 1e-35 ywzA S membrane
NPEIKGBL_00974 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NPEIKGBL_00975 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NPEIKGBL_00976 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NPEIKGBL_00977 8.5e-63 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NPEIKGBL_00978 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NPEIKGBL_00979 8.6e-202 rodA D Belongs to the SEDS family
NPEIKGBL_00980 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NPEIKGBL_00981 7.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPEIKGBL_00982 0.0 vpr O Belongs to the peptidase S8 family
NPEIKGBL_00984 2e-149 sacT K transcriptional antiterminator
NPEIKGBL_00985 5.7e-138 focA P Formate/nitrite transporter
NPEIKGBL_00986 1.3e-249 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPEIKGBL_00987 4.6e-290 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NPEIKGBL_00988 3.5e-28 ywdA
NPEIKGBL_00989 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NPEIKGBL_00990 2.8e-57 pex K Transcriptional regulator PadR-like family
NPEIKGBL_00991 4e-113 ywdD
NPEIKGBL_00993 1.6e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
NPEIKGBL_00994 3.3e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPEIKGBL_00995 9.4e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NPEIKGBL_00996 1.5e-47 ywdI S Family of unknown function (DUF5327)
NPEIKGBL_00997 1.6e-236 ywdJ F Xanthine uracil
NPEIKGBL_00998 4.3e-59 ywdK S small membrane protein
NPEIKGBL_00999 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NPEIKGBL_01001 9.1e-144 spsA M Spore Coat
NPEIKGBL_01002 1e-267 spsB M Capsule polysaccharide biosynthesis protein
NPEIKGBL_01003 2.1e-224 spsC E Belongs to the DegT DnrJ EryC1 family
NPEIKGBL_01004 1.2e-163 spsD 2.3.1.210 K Spore Coat
NPEIKGBL_01005 1e-212 spsE 2.5.1.56 M acid synthase
NPEIKGBL_01006 4.2e-127 spsF M Spore Coat
NPEIKGBL_01007 6.1e-188 spsG M Spore Coat
NPEIKGBL_01008 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NPEIKGBL_01009 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NPEIKGBL_01010 2.9e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NPEIKGBL_01011 6.7e-86 spsL 5.1.3.13 M Spore Coat
NPEIKGBL_01012 5.8e-77
NPEIKGBL_01013 2.2e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NPEIKGBL_01014 1.3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NPEIKGBL_01015 0.0 rocB E arginine degradation protein
NPEIKGBL_01016 1.7e-249 lysP E amino acid
NPEIKGBL_01017 3e-205 ywfA EGP Major facilitator Superfamily
NPEIKGBL_01018 7.3e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NPEIKGBL_01019 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NPEIKGBL_01020 1.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEIKGBL_01021 8e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NPEIKGBL_01022 8.6e-210 bacE EGP Major facilitator Superfamily
NPEIKGBL_01023 1.5e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
NPEIKGBL_01024 2.4e-136 IQ Enoyl-(Acyl carrier protein) reductase
NPEIKGBL_01025 1.1e-146 ywfI C May function as heme-dependent peroxidase
NPEIKGBL_01026 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NPEIKGBL_01027 1.1e-156 cysL K Transcriptional regulator
NPEIKGBL_01028 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NPEIKGBL_01029 4.1e-156 ywfM EG EamA-like transporter family
NPEIKGBL_01030 1.6e-111 rsfA_1
NPEIKGBL_01031 3.1e-36 ywzC S Belongs to the UPF0741 family
NPEIKGBL_01032 1.5e-255 ywfO S COG1078 HD superfamily phosphohydrolases
NPEIKGBL_01033 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
NPEIKGBL_01034 5.3e-78 yffB K Transcriptional regulator
NPEIKGBL_01035 2.3e-238 mmr U Major Facilitator Superfamily
NPEIKGBL_01037 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPEIKGBL_01038 9.5e-71 ywhA K Transcriptional regulator
NPEIKGBL_01039 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NPEIKGBL_01040 3.3e-118 ywhC S Peptidase family M50
NPEIKGBL_01041 3.8e-93 ywhD S YwhD family
NPEIKGBL_01042 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NPEIKGBL_01043 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NPEIKGBL_01044 2.7e-168 speB 3.5.3.11 E Belongs to the arginase family
NPEIKGBL_01046 1.4e-57 V ATPases associated with a variety of cellular activities
NPEIKGBL_01049 1.7e-20
NPEIKGBL_01052 8.9e-79 S aspartate phosphatase
NPEIKGBL_01053 1.6e-199 ywhK CO amine dehydrogenase activity
NPEIKGBL_01054 2.5e-245 ywhL CO amine dehydrogenase activity
NPEIKGBL_01056 1.1e-247 L Peptidase, M16
NPEIKGBL_01057 3e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
NPEIKGBL_01058 5.5e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NPEIKGBL_01059 3.3e-132 cbiO V ABC transporter
NPEIKGBL_01061 4.9e-270 C Fe-S oxidoreductases
NPEIKGBL_01062 1e-07 S Bacteriocin subtilosin A
NPEIKGBL_01063 4.7e-73 ywiB S protein conserved in bacteria
NPEIKGBL_01064 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NPEIKGBL_01065 1.3e-213 narK P COG2223 Nitrate nitrite transporter
NPEIKGBL_01066 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
NPEIKGBL_01067 1.7e-139 ywiC S YwiC-like protein
NPEIKGBL_01068 7e-86 arfM T cyclic nucleotide binding
NPEIKGBL_01069 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPEIKGBL_01070 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
NPEIKGBL_01071 1.9e-95 narJ 1.7.5.1 C nitrate reductase
NPEIKGBL_01072 9.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
NPEIKGBL_01073 1.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPEIKGBL_01074 0.0 ywjA V ABC transporter
NPEIKGBL_01075 3.4e-94 ywjB H RibD C-terminal domain
NPEIKGBL_01076 2.7e-42 ywjC
NPEIKGBL_01077 5.6e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NPEIKGBL_01078 8.3e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NPEIKGBL_01079 0.0 fadF C COG0247 Fe-S oxidoreductase
NPEIKGBL_01080 1.7e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NPEIKGBL_01081 1.1e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPEIKGBL_01082 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPEIKGBL_01083 2.3e-90 ywjG S Domain of unknown function (DUF2529)
NPEIKGBL_01084 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NPEIKGBL_01085 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NPEIKGBL_01086 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NPEIKGBL_01087 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPEIKGBL_01088 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NPEIKGBL_01089 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NPEIKGBL_01090 1.1e-32 rpmE J Binds the 23S rRNA
NPEIKGBL_01091 7e-104 tdk 2.7.1.21 F thymidine kinase
NPEIKGBL_01092 0.0 sfcA 1.1.1.38 C malic enzyme
NPEIKGBL_01093 8.6e-160 ywkB S Membrane transport protein
NPEIKGBL_01094 1.6e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NPEIKGBL_01095 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEIKGBL_01096 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPEIKGBL_01097 6.6e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPEIKGBL_01099 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
NPEIKGBL_01100 6.1e-112 spoIIR S stage II sporulation protein R
NPEIKGBL_01101 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NPEIKGBL_01102 5.2e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPEIKGBL_01103 1.7e-91 mntP P Probably functions as a manganese efflux pump
NPEIKGBL_01104 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPEIKGBL_01105 8.3e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NPEIKGBL_01106 7.2e-95 ywlG S Belongs to the UPF0340 family
NPEIKGBL_01107 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPEIKGBL_01108 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPEIKGBL_01109 2.5e-62 atpI S ATP synthase
NPEIKGBL_01110 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NPEIKGBL_01111 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPEIKGBL_01112 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPEIKGBL_01113 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPEIKGBL_01114 2e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPEIKGBL_01115 1.9e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPEIKGBL_01116 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPEIKGBL_01117 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NPEIKGBL_01118 4.8e-87 ywmA
NPEIKGBL_01119 1.3e-32 ywzB S membrane
NPEIKGBL_01120 3.4e-132 ywmB S TATA-box binding
NPEIKGBL_01121 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPEIKGBL_01122 8.6e-174 spoIID D Stage II sporulation protein D
NPEIKGBL_01123 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NPEIKGBL_01124 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NPEIKGBL_01126 3.8e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NPEIKGBL_01127 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NPEIKGBL_01128 4.6e-104 S response regulator aspartate phosphatase
NPEIKGBL_01129 3.9e-84 ywmF S Peptidase M50
NPEIKGBL_01130 3.8e-11 csbD K CsbD-like
NPEIKGBL_01131 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NPEIKGBL_01132 1.7e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NPEIKGBL_01133 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NPEIKGBL_01134 1.7e-64 ywnA K Transcriptional regulator
NPEIKGBL_01135 1.1e-113 ywnB S NAD(P)H-binding
NPEIKGBL_01136 1.7e-58 ywnC S Family of unknown function (DUF5362)
NPEIKGBL_01137 2.3e-72 mta K transcriptional
NPEIKGBL_01138 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPEIKGBL_01139 2.2e-70 ywnF S Family of unknown function (DUF5392)
NPEIKGBL_01140 1.7e-08 ywnC S Family of unknown function (DUF5362)
NPEIKGBL_01141 1.7e-87 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NPEIKGBL_01142 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NPEIKGBL_01143 4.2e-71 ywnJ S VanZ like family
NPEIKGBL_01144 1.4e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NPEIKGBL_01145 1.6e-58 nrgB K Belongs to the P(II) protein family
NPEIKGBL_01146 4.3e-225 amt P Ammonium transporter
NPEIKGBL_01147 2.2e-76
NPEIKGBL_01148 1.5e-103 phzA Q Isochorismatase family
NPEIKGBL_01149 1.8e-240 ywoD EGP Major facilitator superfamily
NPEIKGBL_01150 1.3e-279 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NPEIKGBL_01151 4.7e-231 ywoF P Right handed beta helix region
NPEIKGBL_01152 6e-211 ywoG EGP Major facilitator Superfamily
NPEIKGBL_01153 2.1e-70 ywoH K COG1846 Transcriptional regulators
NPEIKGBL_01154 3e-44 spoIIID K Stage III sporulation protein D
NPEIKGBL_01155 3.5e-180 mbl D Rod shape-determining protein
NPEIKGBL_01156 1.7e-124 flhO N flagellar basal body
NPEIKGBL_01157 1.5e-141 flhP N flagellar basal body
NPEIKGBL_01158 2.3e-198 S aspartate phosphatase
NPEIKGBL_01159 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NPEIKGBL_01160 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPEIKGBL_01161 1.4e-153 ywpD T Histidine kinase
NPEIKGBL_01162 5.2e-50 srtA 3.4.22.70 M Sortase family
NPEIKGBL_01163 1.1e-66 ywpF S YwpF-like protein
NPEIKGBL_01164 1.3e-66 ywpG
NPEIKGBL_01165 7e-56 ssbB L Single-stranded DNA-binding protein
NPEIKGBL_01166 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
NPEIKGBL_01167 1.8e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NPEIKGBL_01168 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NPEIKGBL_01169 2.7e-307 ywqB S SWIM zinc finger
NPEIKGBL_01170 1.2e-17
NPEIKGBL_01171 2e-116 ywqC M biosynthesis protein
NPEIKGBL_01172 8.4e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NPEIKGBL_01173 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NPEIKGBL_01174 2.6e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NPEIKGBL_01175 2.1e-151 ywqG S Domain of unknown function (DUF1963)
NPEIKGBL_01176 7.4e-23 S Domain of unknown function (DUF5082)
NPEIKGBL_01177 3.9e-38 ywqI S Family of unknown function (DUF5344)
NPEIKGBL_01178 3.5e-242 ywqJ S Pre-toxin TG
NPEIKGBL_01179 3.9e-25
NPEIKGBL_01180 3.9e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NPEIKGBL_01181 1.4e-161 K Transcriptional regulator
NPEIKGBL_01182 3.3e-100 ywqN S NAD(P)H-dependent
NPEIKGBL_01184 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
NPEIKGBL_01185 1.2e-103 ywrB P Chromate transporter
NPEIKGBL_01186 8e-82 ywrC K Transcriptional regulator
NPEIKGBL_01187 2.3e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NPEIKGBL_01188 1.4e-53 S Domain of unknown function (DUF4181)
NPEIKGBL_01189 9e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NPEIKGBL_01190 3.7e-12
NPEIKGBL_01191 6e-210 cotH M Spore Coat
NPEIKGBL_01192 8.2e-131 cotB
NPEIKGBL_01193 7.5e-126 ywrJ
NPEIKGBL_01194 3.2e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NPEIKGBL_01195 1.1e-169 alsR K LysR substrate binding domain
NPEIKGBL_01196 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NPEIKGBL_01197 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NPEIKGBL_01198 4.4e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NPEIKGBL_01199 8e-48 ywsA S Protein of unknown function (DUF3892)
NPEIKGBL_01200 1.1e-92 batE T Sh3 type 3 domain protein
NPEIKGBL_01201 1.8e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NPEIKGBL_01202 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
NPEIKGBL_01203 9.5e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NPEIKGBL_01204 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NPEIKGBL_01205 8.4e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPEIKGBL_01206 2.7e-177 rbsR K transcriptional
NPEIKGBL_01207 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NPEIKGBL_01208 8.6e-70 pgsC S biosynthesis protein
NPEIKGBL_01209 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NPEIKGBL_01210 1.4e-20 ywtC
NPEIKGBL_01211 1e-238 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NPEIKGBL_01212 9.1e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NPEIKGBL_01213 8.4e-171 ywtF K Transcriptional regulator
NPEIKGBL_01214 7.8e-247 ywtG EGP Major facilitator Superfamily
NPEIKGBL_01215 4.3e-211 gerAC S Spore germination protein
NPEIKGBL_01216 5.4e-198 gerBB E Spore germination protein
NPEIKGBL_01217 3.5e-266 gerBA EG Spore germination protein
NPEIKGBL_01218 6e-190 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NPEIKGBL_01219 8e-216 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPEIKGBL_01220 3.3e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPEIKGBL_01221 7.4e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPEIKGBL_01222 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NPEIKGBL_01223 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NPEIKGBL_01224 6e-95 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NPEIKGBL_01225 1.6e-87 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NPEIKGBL_01226 2.1e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NPEIKGBL_01227 1.1e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NPEIKGBL_01228 4e-240 ggaA M Glycosyltransferase like family 2
NPEIKGBL_01229 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPEIKGBL_01230 1e-132 tagG GM Transport permease protein
NPEIKGBL_01231 2.1e-272 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NPEIKGBL_01232 4.5e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NPEIKGBL_01233 3.7e-23 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NPEIKGBL_01234 2.4e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NPEIKGBL_01235 1.6e-88 M Glycosyltransferase like family 2
NPEIKGBL_01236 4.7e-213 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPEIKGBL_01237 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NPEIKGBL_01238 2.7e-12
NPEIKGBL_01239 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NPEIKGBL_01240 4.5e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NPEIKGBL_01241 1.5e-94 M Glycosyltransferase like family 2
NPEIKGBL_01242 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NPEIKGBL_01243 2.2e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPEIKGBL_01244 7.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NPEIKGBL_01245 9.9e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NPEIKGBL_01246 5.4e-262 tuaE M Teichuronic acid biosynthesis protein
NPEIKGBL_01247 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
NPEIKGBL_01248 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
NPEIKGBL_01249 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NPEIKGBL_01250 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NPEIKGBL_01251 6e-163 yvhJ K Transcriptional regulator
NPEIKGBL_01252 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NPEIKGBL_01253 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NPEIKGBL_01254 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEIKGBL_01255 2.1e-154 degV S protein conserved in bacteria
NPEIKGBL_01256 1.2e-266 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NPEIKGBL_01257 3.7e-45 comFB S Late competence development protein ComFB
NPEIKGBL_01258 2.3e-125 comFC S Phosphoribosyl transferase domain
NPEIKGBL_01259 7e-74 yvyF S flagellar protein
NPEIKGBL_01260 2.3e-38 flgM KNU Negative regulator of flagellin synthesis
NPEIKGBL_01261 2.3e-76 flgN NOU FlgN protein
NPEIKGBL_01262 2e-264 flgK N flagellar hook-associated protein
NPEIKGBL_01263 7.8e-155 flgL N Belongs to the bacterial flagellin family
NPEIKGBL_01264 1.3e-49 yviE
NPEIKGBL_01265 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NPEIKGBL_01266 9.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NPEIKGBL_01267 1.5e-124 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NPEIKGBL_01268 1.2e-55 flaG N flagellar protein FlaG
NPEIKGBL_01269 5.9e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NPEIKGBL_01270 2.9e-69 fliS N flagellar protein FliS
NPEIKGBL_01271 2.5e-08 fliT S bacterial-type flagellum organization
NPEIKGBL_01272 2.8e-66
NPEIKGBL_01273 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPEIKGBL_01274 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPEIKGBL_01275 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPEIKGBL_01276 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NPEIKGBL_01277 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
NPEIKGBL_01278 1.6e-123 ftsE D cell division ATP-binding protein FtsE
NPEIKGBL_01279 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NPEIKGBL_01280 1.5e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NPEIKGBL_01281 5.3e-56 swrA S Swarming motility protein
NPEIKGBL_01282 5.4e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPEIKGBL_01283 9.6e-226 yvkA EGP Major facilitator Superfamily
NPEIKGBL_01284 1e-99 yvkB K Transcriptional regulator
NPEIKGBL_01285 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NPEIKGBL_01286 1.2e-30 csbA S protein conserved in bacteria
NPEIKGBL_01287 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPEIKGBL_01288 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NPEIKGBL_01289 1.1e-11 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NPEIKGBL_01290 3.1e-48 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NPEIKGBL_01291 6.7e-34 yvkN
NPEIKGBL_01292 8e-49 yvlA
NPEIKGBL_01293 7.5e-168 yvlB S Putative adhesin
NPEIKGBL_01294 2.6e-26 pspB KT PspC domain
NPEIKGBL_01295 1.2e-50 yvlD S Membrane
NPEIKGBL_01296 2.7e-203 yvmA EGP Major facilitator Superfamily
NPEIKGBL_01297 2e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
NPEIKGBL_01298 8.8e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NPEIKGBL_01299 2e-230 cypX 1.14.15.13 C Cytochrome P450
NPEIKGBL_01300 9.4e-83 adcR K helix_turn_helix multiple antibiotic resistance protein
NPEIKGBL_01301 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NPEIKGBL_01302 4e-133 yvoA K transcriptional
NPEIKGBL_01303 7.5e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPEIKGBL_01304 7.8e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NPEIKGBL_01305 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPEIKGBL_01306 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPEIKGBL_01307 5.3e-162 yvoD P COG0370 Fe2 transport system protein B
NPEIKGBL_01308 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NPEIKGBL_01309 8.7e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NPEIKGBL_01310 3.9e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NPEIKGBL_01311 1e-139 yvpB NU protein conserved in bacteria
NPEIKGBL_01312 4.1e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NPEIKGBL_01313 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NPEIKGBL_01314 3.8e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NPEIKGBL_01315 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NPEIKGBL_01316 1.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NPEIKGBL_01317 1.9e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NPEIKGBL_01318 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NPEIKGBL_01319 1.4e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NPEIKGBL_01320 3.7e-94 Otg1 S Predicted membrane protein (DUF2339)
NPEIKGBL_01321 4.5e-68
NPEIKGBL_01323 5.4e-63
NPEIKGBL_01324 3.8e-75
NPEIKGBL_01325 0.0
NPEIKGBL_01327 0.0 msbA2 3.6.3.44 V ABC transporter
NPEIKGBL_01328 6.9e-278 S COG0457 FOG TPR repeat
NPEIKGBL_01329 1.1e-97 usp CBM50 M protein conserved in bacteria
NPEIKGBL_01330 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPEIKGBL_01331 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NPEIKGBL_01332 5.7e-166 rapZ S Displays ATPase and GTPase activities
NPEIKGBL_01333 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NPEIKGBL_01334 1.4e-170 whiA K May be required for sporulation
NPEIKGBL_01335 1.6e-36 crh G Phosphocarrier protein Chr
NPEIKGBL_01336 4e-144 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NPEIKGBL_01337 1.8e-33
NPEIKGBL_01338 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEIKGBL_01339 2e-194 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NPEIKGBL_01340 5.6e-141 yvcR V ABC transporter, ATP-binding protein
NPEIKGBL_01341 0.0 yxdM V ABC transporter (permease)
NPEIKGBL_01342 2.5e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPEIKGBL_01343 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NPEIKGBL_01344 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NPEIKGBL_01345 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
NPEIKGBL_01346 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NPEIKGBL_01347 3.6e-174 yvdE K Transcriptional regulator
NPEIKGBL_01348 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NPEIKGBL_01349 6.9e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NPEIKGBL_01350 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
NPEIKGBL_01351 9.5e-147 malD P transport
NPEIKGBL_01352 2.4e-156 malA S Protein of unknown function (DUF1189)
NPEIKGBL_01353 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NPEIKGBL_01354 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NPEIKGBL_01355 6.1e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NPEIKGBL_01356 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPEIKGBL_01358 1.5e-183 S Patatin-like phospholipase
NPEIKGBL_01359 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
NPEIKGBL_01360 1.4e-92 yvdQ S Protein of unknown function (DUF3231)
NPEIKGBL_01361 2.7e-49 sugE P Small Multidrug Resistance protein
NPEIKGBL_01362 1.5e-50 ykkC P Small Multidrug Resistance protein
NPEIKGBL_01363 2.6e-106 yvdT K Transcriptional regulator
NPEIKGBL_01364 1.8e-295 yveA E amino acid
NPEIKGBL_01365 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NPEIKGBL_01366 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NPEIKGBL_01367 3.2e-261 pbpE V Beta-lactamase
NPEIKGBL_01368 2.1e-123 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NPEIKGBL_01369 8.8e-34 MA20_18690 S Protein of unknown function (DUF3237)
NPEIKGBL_01370 1.7e-92 padC Q Phenolic acid decarboxylase
NPEIKGBL_01372 4.7e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NPEIKGBL_01373 6.3e-76 slr K transcriptional
NPEIKGBL_01374 4e-122 ywqC M biosynthesis protein
NPEIKGBL_01375 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NPEIKGBL_01376 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NPEIKGBL_01377 3.8e-223 epsD GT4 M Glycosyl transferase 4-like
NPEIKGBL_01378 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NPEIKGBL_01379 8.4e-218 epsF GT4 M Glycosyl transferases group 1
NPEIKGBL_01380 1.1e-206 epsG S EpsG family
NPEIKGBL_01381 2e-194 epsH GT2 S Glycosyltransferase like family 2
NPEIKGBL_01382 4.4e-205 epsI GM pyruvyl transferase
NPEIKGBL_01383 4.7e-196 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NPEIKGBL_01384 2.8e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPEIKGBL_01385 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NPEIKGBL_01386 2.1e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NPEIKGBL_01387 1.7e-218 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NPEIKGBL_01388 3.5e-185 yvfF GM Exopolysaccharide biosynthesis protein
NPEIKGBL_01389 1e-31 yvfG S YvfG protein
NPEIKGBL_01390 1.1e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NPEIKGBL_01391 4.8e-307 yvfH C L-lactate permease
NPEIKGBL_01392 1e-112 yvfI K COG2186 Transcriptional regulators
NPEIKGBL_01393 5.2e-184 lacR K Transcriptional regulator
NPEIKGBL_01394 1.5e-228 cycB G COG2182 Maltose-binding periplasmic proteins domains
NPEIKGBL_01395 4.2e-231 malC P COG1175 ABC-type sugar transport systems, permease components
NPEIKGBL_01396 7.2e-150 ganQ P transport
NPEIKGBL_01397 0.0 lacA 3.2.1.23 G beta-galactosidase
NPEIKGBL_01398 2.2e-251 galA 3.2.1.89 G arabinogalactan
NPEIKGBL_01399 1.4e-199 rsbU 3.1.3.3 T response regulator
NPEIKGBL_01400 4.4e-157 rsbQ S Alpha/beta hydrolase family
NPEIKGBL_01402 8.9e-159 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NPEIKGBL_01403 5.8e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
NPEIKGBL_01404 3e-196 desK 2.7.13.3 T Histidine kinase
NPEIKGBL_01405 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEIKGBL_01406 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NPEIKGBL_01407 1e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NPEIKGBL_01408 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NPEIKGBL_01409 5.2e-195 yvbX S Glycosyl hydrolase
NPEIKGBL_01410 8.1e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NPEIKGBL_01411 7.2e-156 yvbV EG EamA-like transporter family
NPEIKGBL_01412 1.5e-155 yvbU K Transcriptional regulator
NPEIKGBL_01414 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPEIKGBL_01415 5.5e-203 araR K transcriptional
NPEIKGBL_01416 1.6e-252 araE EGP Major facilitator Superfamily
NPEIKGBL_01417 2.4e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NPEIKGBL_01418 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPEIKGBL_01419 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NPEIKGBL_01420 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPEIKGBL_01421 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NPEIKGBL_01422 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPEIKGBL_01423 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
NPEIKGBL_01424 0.0 tcaA S response to antibiotic
NPEIKGBL_01425 8e-123 exoY M Membrane
NPEIKGBL_01426 8.6e-113 yvbH S YvbH-like oligomerisation region
NPEIKGBL_01427 6.4e-103 yvbG U UPF0056 membrane protein
NPEIKGBL_01428 3.5e-97 yvbF K Belongs to the GbsR family
NPEIKGBL_01429 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NPEIKGBL_01430 1.3e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NPEIKGBL_01431 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NPEIKGBL_01432 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NPEIKGBL_01433 1.6e-59 yvbF K Belongs to the GbsR family
NPEIKGBL_01434 5.7e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NPEIKGBL_01435 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NPEIKGBL_01436 7.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NPEIKGBL_01437 1.2e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NPEIKGBL_01438 3e-224 NT chemotaxis protein
NPEIKGBL_01439 2.2e-54 yodB K transcriptional
NPEIKGBL_01440 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
NPEIKGBL_01441 4e-69 K transcriptional
NPEIKGBL_01442 7.5e-36 yvzC K Transcriptional
NPEIKGBL_01443 3.4e-151 yvaM S Serine aminopeptidase, S33
NPEIKGBL_01444 2.4e-23 secG U Preprotein translocase subunit SecG
NPEIKGBL_01445 5.6e-143 est 3.1.1.1 S Carboxylesterase
NPEIKGBL_01446 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPEIKGBL_01447 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NPEIKGBL_01449 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEIKGBL_01450 3.9e-99 K Bacterial regulatory proteins, tetR family
NPEIKGBL_01451 2.4e-54 yvaE P Small Multidrug Resistance protein
NPEIKGBL_01452 1.3e-72 yvaD S Family of unknown function (DUF5360)
NPEIKGBL_01453 0.0 yvaC S Fusaric acid resistance protein-like
NPEIKGBL_01454 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NPEIKGBL_01455 4e-195 yvaA 1.1.1.371 S Oxidoreductase
NPEIKGBL_01456 2.2e-48 csoR S transcriptional
NPEIKGBL_01457 5.9e-29 copZ P Copper resistance protein CopZ
NPEIKGBL_01458 0.0 copA 3.6.3.54 P P-type ATPase
NPEIKGBL_01459 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NPEIKGBL_01460 1.6e-104 bdbD O Thioredoxin
NPEIKGBL_01461 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
NPEIKGBL_01462 1.6e-106 yvgT S membrane
NPEIKGBL_01464 0.0 helD 3.6.4.12 L DNA helicase
NPEIKGBL_01465 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NPEIKGBL_01466 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NPEIKGBL_01467 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NPEIKGBL_01468 4.6e-85 yvgO
NPEIKGBL_01469 1.1e-155 yvgN S reductase
NPEIKGBL_01470 1.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
NPEIKGBL_01471 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NPEIKGBL_01472 4.9e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NPEIKGBL_01473 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NPEIKGBL_01474 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NPEIKGBL_01475 6.5e-16 S Small spore protein J (Spore_SspJ)
NPEIKGBL_01476 4.9e-236 yvsH E Arginine ornithine antiporter
NPEIKGBL_01477 1.7e-176 fhuD P ABC transporter
NPEIKGBL_01478 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEIKGBL_01479 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEIKGBL_01480 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
NPEIKGBL_01481 4.5e-174 M Efflux transporter rnd family, mfp subunit
NPEIKGBL_01482 7.1e-124 macB V ABC transporter, ATP-binding protein
NPEIKGBL_01483 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NPEIKGBL_01484 1.3e-64 yvrL S Regulatory protein YrvL
NPEIKGBL_01485 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
NPEIKGBL_01486 5.2e-19 S YvrJ protein family
NPEIKGBL_01487 9.5e-98 yvrI K RNA polymerase
NPEIKGBL_01488 7.2e-23
NPEIKGBL_01489 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEIKGBL_01490 0.0 T PhoQ Sensor
NPEIKGBL_01491 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
NPEIKGBL_01492 3.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEIKGBL_01493 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NPEIKGBL_01494 1.6e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEIKGBL_01495 5.6e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NPEIKGBL_01496 3.6e-100 yvqK 2.5.1.17 S Adenosyltransferase
NPEIKGBL_01497 1.4e-226 yvqJ EGP Major facilitator Superfamily
NPEIKGBL_01498 7.3e-62 liaI S membrane
NPEIKGBL_01499 9.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NPEIKGBL_01500 1.7e-114 liaG S Putative adhesin
NPEIKGBL_01501 3.6e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NPEIKGBL_01502 2.6e-178 vraS 2.7.13.3 T Histidine kinase
NPEIKGBL_01503 3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEIKGBL_01504 1.1e-182 gerAC S Spore germination B3/ GerAC like, C-terminal
NPEIKGBL_01505 3.8e-196 gerAB E Spore germination protein
NPEIKGBL_01506 1.4e-246 gerAA EG Spore germination protein
NPEIKGBL_01507 2.3e-24 S Protein of unknown function (DUF3970)
NPEIKGBL_01508 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPEIKGBL_01509 4.3e-158 yuxN K Transcriptional regulator
NPEIKGBL_01510 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
NPEIKGBL_01511 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEIKGBL_01512 1.5e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPEIKGBL_01513 8e-79 dps P Ferritin-like domain
NPEIKGBL_01514 2.6e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEIKGBL_01515 4.2e-301 pepF2 E COG1164 Oligoendopeptidase F
NPEIKGBL_01516 2.5e-66 S YusW-like protein
NPEIKGBL_01517 1e-153 yusV 3.6.3.34 HP ABC transporter
NPEIKGBL_01518 3.8e-47 yusU S Protein of unknown function (DUF2573)
NPEIKGBL_01519 3.7e-157 yusT K LysR substrate binding domain
NPEIKGBL_01520 3.8e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEIKGBL_01521 2.7e-64 yusQ S Tautomerase enzyme
NPEIKGBL_01522 3.8e-293 yusP P Major facilitator superfamily
NPEIKGBL_01523 2.3e-73 yusO K Iron dependent repressor, N-terminal DNA binding domain
NPEIKGBL_01524 5.4e-53 yusN M Coat F domain
NPEIKGBL_01525 5.1e-40
NPEIKGBL_01526 8.4e-165 fadM E Proline dehydrogenase
NPEIKGBL_01527 8.1e-09 S YuzL-like protein
NPEIKGBL_01528 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NPEIKGBL_01529 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
NPEIKGBL_01530 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NPEIKGBL_01531 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NPEIKGBL_01532 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NPEIKGBL_01533 1.1e-39 yusG S Protein of unknown function (DUF2553)
NPEIKGBL_01534 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NPEIKGBL_01535 5.6e-55 traF CO Thioredoxin
NPEIKGBL_01536 3.2e-56 yusD S SCP-2 sterol transfer family
NPEIKGBL_01537 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPEIKGBL_01538 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NPEIKGBL_01539 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
NPEIKGBL_01540 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NPEIKGBL_01541 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NPEIKGBL_01542 5.9e-244 sufD O assembly protein SufD
NPEIKGBL_01543 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NPEIKGBL_01544 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NPEIKGBL_01545 7.9e-271 sufB O FeS cluster assembly
NPEIKGBL_01546 2.9e-66 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEIKGBL_01547 6.7e-41
NPEIKGBL_01549 9.3e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NPEIKGBL_01550 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NPEIKGBL_01551 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NPEIKGBL_01552 1.1e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NPEIKGBL_01553 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
NPEIKGBL_01554 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
NPEIKGBL_01555 3.3e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NPEIKGBL_01556 1.1e-135 yurK K UTRA
NPEIKGBL_01557 1.2e-205 msmX P Belongs to the ABC transporter superfamily
NPEIKGBL_01558 1.2e-168 bsn L Ribonuclease
NPEIKGBL_01559 2.1e-230 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NPEIKGBL_01560 2.7e-238 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NPEIKGBL_01562 3.2e-186 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NPEIKGBL_01563 2.6e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NPEIKGBL_01564 3e-145 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NPEIKGBL_01565 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NPEIKGBL_01566 3.6e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NPEIKGBL_01567 3.5e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NPEIKGBL_01568 2.9e-279 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NPEIKGBL_01569 7.4e-223 pbuX F xanthine
NPEIKGBL_01570 9.1e-232 pbuX F Permease family
NPEIKGBL_01571 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
NPEIKGBL_01572 1.6e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NPEIKGBL_01573 8.2e-60 yunG
NPEIKGBL_01574 4.3e-171 yunF S Protein of unknown function DUF72
NPEIKGBL_01575 8.5e-140 yunE S membrane transporter protein
NPEIKGBL_01576 7.1e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NPEIKGBL_01577 1.1e-47 yunC S Domain of unknown function (DUF1805)
NPEIKGBL_01578 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
NPEIKGBL_01579 4.5e-196 lytH M Peptidase, M23
NPEIKGBL_01580 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NPEIKGBL_01581 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPEIKGBL_01582 9.7e-48 yutD S protein conserved in bacteria
NPEIKGBL_01583 1e-75 yutE S Protein of unknown function DUF86
NPEIKGBL_01584 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPEIKGBL_01585 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NPEIKGBL_01586 1e-198 yutH S Spore coat protein
NPEIKGBL_01587 6e-241 hom 1.1.1.3 E homoserine dehydrogenase
NPEIKGBL_01588 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NPEIKGBL_01589 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NPEIKGBL_01590 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NPEIKGBL_01591 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NPEIKGBL_01592 7.4e-55 yuzD S protein conserved in bacteria
NPEIKGBL_01593 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NPEIKGBL_01594 3.2e-39 yuzB S Belongs to the UPF0349 family
NPEIKGBL_01595 2e-198 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NPEIKGBL_01596 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NPEIKGBL_01597 3.7e-63 erpA S Belongs to the HesB IscA family
NPEIKGBL_01598 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEIKGBL_01599 5e-116 paiB K Putative FMN-binding domain
NPEIKGBL_01600 7.9e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPEIKGBL_01602 3.9e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
NPEIKGBL_01603 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
NPEIKGBL_01604 8.4e-27 yuiB S Putative membrane protein
NPEIKGBL_01605 4.7e-117 yuiC S protein conserved in bacteria
NPEIKGBL_01606 1.2e-77 yuiD S protein conserved in bacteria
NPEIKGBL_01607 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NPEIKGBL_01608 3.9e-211 yuiF S antiporter
NPEIKGBL_01609 7.4e-93 bioY S Biotin biosynthesis protein
NPEIKGBL_01610 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
NPEIKGBL_01611 3.9e-167 besA S Putative esterase
NPEIKGBL_01612 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEIKGBL_01613 6.6e-226 entC 5.4.4.2 HQ Isochorismate synthase
NPEIKGBL_01614 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NPEIKGBL_01615 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NPEIKGBL_01616 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEIKGBL_01617 8.5e-36 mbtH S MbtH-like protein
NPEIKGBL_01618 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NPEIKGBL_01619 8.8e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NPEIKGBL_01620 6.5e-229 yukF QT Transcriptional regulator
NPEIKGBL_01621 2.8e-45 esxA S Belongs to the WXG100 family
NPEIKGBL_01622 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NPEIKGBL_01623 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
NPEIKGBL_01624 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NPEIKGBL_01625 0.0 esaA S type VII secretion protein EsaA
NPEIKGBL_01626 5.6e-64 yueC S Family of unknown function (DUF5383)
NPEIKGBL_01627 1.1e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEIKGBL_01628 4.8e-96 yueE S phosphohydrolase
NPEIKGBL_01629 2.9e-24 S Protein of unknown function (DUF2642)
NPEIKGBL_01630 2.8e-69 S Protein of unknown function (DUF2283)
NPEIKGBL_01631 1.2e-189 yueF S transporter activity
NPEIKGBL_01632 1.7e-31 yueG S Spore germination protein gerPA/gerPF
NPEIKGBL_01633 3.1e-37 yueH S YueH-like protein
NPEIKGBL_01634 7.9e-67 yueI S Protein of unknown function (DUF1694)
NPEIKGBL_01635 9.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
NPEIKGBL_01636 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPEIKGBL_01637 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NPEIKGBL_01638 1.1e-22 yuzC
NPEIKGBL_01640 2.2e-128 comQ H Belongs to the FPP GGPP synthase family
NPEIKGBL_01642 3.8e-254 comP 2.7.13.3 T Histidine kinase
NPEIKGBL_01643 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEIKGBL_01644 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
NPEIKGBL_01645 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NPEIKGBL_01646 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPEIKGBL_01647 2.4e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPEIKGBL_01648 1.4e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPEIKGBL_01649 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPEIKGBL_01650 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPEIKGBL_01651 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NPEIKGBL_01652 5e-15
NPEIKGBL_01653 8.2e-233 maeN C COG3493 Na citrate symporter
NPEIKGBL_01654 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
NPEIKGBL_01655 1.4e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
NPEIKGBL_01656 1.6e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NPEIKGBL_01657 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NPEIKGBL_01658 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
NPEIKGBL_01659 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NPEIKGBL_01660 6.3e-78 yufK S Family of unknown function (DUF5366)
NPEIKGBL_01661 1.8e-74 yuxK S protein conserved in bacteria
NPEIKGBL_01662 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NPEIKGBL_01663 4.2e-184 yuxJ EGP Major facilitator Superfamily
NPEIKGBL_01665 1.9e-115 kapD L the KinA pathway to sporulation
NPEIKGBL_01666 7.4e-70 kapB G Kinase associated protein B
NPEIKGBL_01667 2.3e-232 T PhoQ Sensor
NPEIKGBL_01668 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NPEIKGBL_01669 4.6e-39 yugE S Domain of unknown function (DUF1871)
NPEIKGBL_01670 4.9e-156 yugF I Hydrolase
NPEIKGBL_01671 1.6e-85 alaR K Transcriptional regulator
NPEIKGBL_01672 2.1e-199 yugH 2.6.1.1 E Aminotransferase
NPEIKGBL_01673 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NPEIKGBL_01674 1.1e-34 yuzA S Domain of unknown function (DUF378)
NPEIKGBL_01675 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NPEIKGBL_01676 3.1e-228 yugK C Dehydrogenase
NPEIKGBL_01677 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NPEIKGBL_01679 1.3e-72 yugN S YugN-like family
NPEIKGBL_01680 2.2e-182 yugO P COG1226 Kef-type K transport systems
NPEIKGBL_01681 1.1e-53 mstX S Membrane-integrating protein Mistic
NPEIKGBL_01682 3.7e-36
NPEIKGBL_01683 1.4e-116 yugP S Zn-dependent protease
NPEIKGBL_01684 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NPEIKGBL_01685 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NPEIKGBL_01686 2.1e-72 yugU S Uncharacterised protein family UPF0047
NPEIKGBL_01687 1e-35
NPEIKGBL_01688 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NPEIKGBL_01689 3.5e-224 mcpA NT chemotaxis protein
NPEIKGBL_01690 6.9e-220 mcpA NT chemotaxis protein
NPEIKGBL_01691 8.5e-295 mcpA NT chemotaxis protein
NPEIKGBL_01692 2.1e-237 mcpA NT chemotaxis protein
NPEIKGBL_01693 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NPEIKGBL_01694 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NPEIKGBL_01695 2.7e-266 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NPEIKGBL_01696 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NPEIKGBL_01697 1.6e-249 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NPEIKGBL_01698 3.3e-183 ygjR S Oxidoreductase
NPEIKGBL_01699 1.3e-194 yubA S transporter activity
NPEIKGBL_01700 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NPEIKGBL_01702 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NPEIKGBL_01703 5.4e-273 yubD P Major Facilitator Superfamily
NPEIKGBL_01704 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPEIKGBL_01705 1e-38 yiaA S yiaA/B two helix domain
NPEIKGBL_01706 2.7e-236 ktrB P Potassium
NPEIKGBL_01707 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
NPEIKGBL_01708 2.2e-91 yuaB
NPEIKGBL_01709 5.5e-95 yuaC K Belongs to the GbsR family
NPEIKGBL_01710 8.8e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NPEIKGBL_01711 1.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
NPEIKGBL_01712 2.3e-107 yuaD
NPEIKGBL_01713 3.9e-84 yuaE S DinB superfamily
NPEIKGBL_01714 1e-74 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NPEIKGBL_01715 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
NPEIKGBL_01716 3.2e-92 M1-753 M FR47-like protein
NPEIKGBL_01717 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
NPEIKGBL_01718 3.4e-39 S COG NOG14552 non supervised orthologous group
NPEIKGBL_01723 2e-08
NPEIKGBL_01730 1.3e-09
NPEIKGBL_01731 7.8e-08
NPEIKGBL_01740 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NPEIKGBL_01741 3e-196 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NPEIKGBL_01742 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NPEIKGBL_01743 1.6e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NPEIKGBL_01744 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NPEIKGBL_01745 4.5e-54 tspO T membrane
NPEIKGBL_01746 3.7e-204 cotI S Spore coat protein
NPEIKGBL_01747 6.9e-217 cotSA M Glycosyl transferases group 1
NPEIKGBL_01748 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
NPEIKGBL_01750 3.6e-235 ytcC M Glycosyltransferase Family 4
NPEIKGBL_01751 3.1e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NPEIKGBL_01752 6.4e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NPEIKGBL_01753 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
NPEIKGBL_01754 4.4e-132 dksA T COG1734 DnaK suppressor protein
NPEIKGBL_01755 4.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
NPEIKGBL_01756 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NPEIKGBL_01757 1.4e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NPEIKGBL_01758 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NPEIKGBL_01759 3.6e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NPEIKGBL_01760 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NPEIKGBL_01761 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
NPEIKGBL_01762 2.1e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NPEIKGBL_01763 1.1e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NPEIKGBL_01764 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NPEIKGBL_01765 1.1e-24 S Domain of Unknown Function (DUF1540)
NPEIKGBL_01766 1.8e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NPEIKGBL_01767 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
NPEIKGBL_01768 3.6e-41 rpmE2 J Ribosomal protein L31
NPEIKGBL_01769 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NPEIKGBL_01770 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPEIKGBL_01771 2.4e-72 ytkA S YtkA-like
NPEIKGBL_01773 2.1e-76 dps P Belongs to the Dps family
NPEIKGBL_01774 5.4e-63 ytkC S Bacteriophage holin family
NPEIKGBL_01775 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NPEIKGBL_01776 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NPEIKGBL_01777 1.4e-144 ytlC P ABC transporter
NPEIKGBL_01778 4.2e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NPEIKGBL_01779 2.7e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NPEIKGBL_01780 1.2e-38 ytmB S Protein of unknown function (DUF2584)
NPEIKGBL_01781 1.5e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NPEIKGBL_01782 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPEIKGBL_01783 0.0 asnB 6.3.5.4 E Asparagine synthase
NPEIKGBL_01784 2.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NPEIKGBL_01785 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NPEIKGBL_01786 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
NPEIKGBL_01787 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NPEIKGBL_01788 3.3e-106 ytqB J Putative rRNA methylase
NPEIKGBL_01789 2.1e-190 yhcC S Fe-S oxidoreductase
NPEIKGBL_01790 6.7e-41 ytzC S Protein of unknown function (DUF2524)
NPEIKGBL_01792 5.1e-66 ytrA K GntR family transcriptional regulator
NPEIKGBL_01793 1.1e-161 ytrB P abc transporter atp-binding protein
NPEIKGBL_01794 6.1e-169 P ABC-2 family transporter protein
NPEIKGBL_01795 6.3e-150
NPEIKGBL_01796 3.1e-127 ytrE V ABC transporter, ATP-binding protein
NPEIKGBL_01797 1.9e-234 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NPEIKGBL_01798 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEIKGBL_01799 5.6e-186 T PhoQ Sensor
NPEIKGBL_01800 1.1e-138 bceA V ABC transporter, ATP-binding protein
NPEIKGBL_01801 0.0 bceB V ABC transporter (permease)
NPEIKGBL_01802 1.9e-42 yttA 2.7.13.3 S Pfam Transposase IS66
NPEIKGBL_01803 1.3e-210 yttB EGP Major facilitator Superfamily
NPEIKGBL_01804 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NPEIKGBL_01805 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NPEIKGBL_01806 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPEIKGBL_01807 2.1e-51 ytwF P Sulfurtransferase
NPEIKGBL_01808 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NPEIKGBL_01809 8.3e-143 amyC P ABC transporter (permease)
NPEIKGBL_01810 6.2e-168 amyD P ABC transporter
NPEIKGBL_01811 4.3e-247 msmE G Bacterial extracellular solute-binding protein
NPEIKGBL_01812 5.6e-189 msmR K Transcriptional regulator
NPEIKGBL_01813 4.1e-172 ytaP S Acetyl xylan esterase (AXE1)
NPEIKGBL_01814 6.8e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NPEIKGBL_01815 1.2e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NPEIKGBL_01816 7.1e-217 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NPEIKGBL_01817 1.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NPEIKGBL_01818 4.2e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NPEIKGBL_01819 3.5e-219 bioI 1.14.14.46 C Cytochrome P450
NPEIKGBL_01820 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NPEIKGBL_01821 8.8e-151 ytcP G COG0395 ABC-type sugar transport system, permease component
NPEIKGBL_01822 1.5e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NPEIKGBL_01823 0.0 ytdP K Transcriptional regulator
NPEIKGBL_01824 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NPEIKGBL_01825 1.6e-218 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NPEIKGBL_01826 1.1e-71 yteS G transport
NPEIKGBL_01827 5e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NPEIKGBL_01828 1.7e-114 yteU S Integral membrane protein
NPEIKGBL_01829 3.1e-26 yteV S Sporulation protein Cse60
NPEIKGBL_01830 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NPEIKGBL_01831 8.2e-232 ytfP S HI0933-like protein
NPEIKGBL_01832 3.6e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPEIKGBL_01833 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPEIKGBL_01834 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NPEIKGBL_01835 4.8e-131 ythP V ABC transporter
NPEIKGBL_01836 1.9e-201 ythQ U Bacterial ABC transporter protein EcsB
NPEIKGBL_01837 6.1e-225 pbuO S permease
NPEIKGBL_01838 1.7e-270 pepV 3.5.1.18 E Dipeptidase
NPEIKGBL_01839 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NPEIKGBL_01840 1.8e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NPEIKGBL_01841 1.1e-164 ytlQ
NPEIKGBL_01842 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NPEIKGBL_01843 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NPEIKGBL_01844 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
NPEIKGBL_01845 2e-45 ytzH S YtzH-like protein
NPEIKGBL_01846 2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPEIKGBL_01847 4.6e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NPEIKGBL_01848 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NPEIKGBL_01849 1.1e-50 ytzB S small secreted protein
NPEIKGBL_01850 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NPEIKGBL_01851 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NPEIKGBL_01852 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NPEIKGBL_01853 9.8e-149 ytpQ S Belongs to the UPF0354 family
NPEIKGBL_01854 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPEIKGBL_01855 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NPEIKGBL_01856 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NPEIKGBL_01857 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPEIKGBL_01858 6.6e-17 ytxH S COG4980 Gas vesicle protein
NPEIKGBL_01859 1.7e-54 ytxJ O Protein of unknown function (DUF2847)
NPEIKGBL_01860 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NPEIKGBL_01861 3.8e-182 ccpA K catabolite control protein A
NPEIKGBL_01862 6e-146 motA N flagellar motor
NPEIKGBL_01863 6.2e-123 motS N Flagellar motor protein
NPEIKGBL_01864 3.5e-224 acuC BQ histone deacetylase
NPEIKGBL_01865 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
NPEIKGBL_01866 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NPEIKGBL_01867 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NPEIKGBL_01868 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPEIKGBL_01870 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPEIKGBL_01871 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NPEIKGBL_01872 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NPEIKGBL_01873 1e-108 yttP K Transcriptional regulator
NPEIKGBL_01874 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NPEIKGBL_01875 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPEIKGBL_01876 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
NPEIKGBL_01877 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
NPEIKGBL_01878 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPEIKGBL_01879 2e-29 sspB S spore protein
NPEIKGBL_01880 1.7e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NPEIKGBL_01881 0.0 ytcJ S amidohydrolase
NPEIKGBL_01882 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPEIKGBL_01883 1.9e-178 sppA OU signal peptide peptidase SppA
NPEIKGBL_01884 8.5e-87 yteJ S RDD family
NPEIKGBL_01885 5.2e-114 ytfI S Protein of unknown function (DUF2953)
NPEIKGBL_01886 8.7e-70 ytfJ S Sporulation protein YtfJ
NPEIKGBL_01887 7.1e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NPEIKGBL_01888 7e-165 ytxK 2.1.1.72 L DNA methylase
NPEIKGBL_01889 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPEIKGBL_01890 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NPEIKGBL_01891 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NPEIKGBL_01892 2e-266 argH 4.3.2.1 E argininosuccinate lyase
NPEIKGBL_01894 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEIKGBL_01895 1.7e-130 ytkL S Belongs to the UPF0173 family
NPEIKGBL_01896 5.5e-172 ytlI K LysR substrate binding domain
NPEIKGBL_01897 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
NPEIKGBL_01898 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
NPEIKGBL_01899 3.7e-148 tcyK M Bacterial periplasmic substrate-binding proteins
NPEIKGBL_01900 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
NPEIKGBL_01901 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
NPEIKGBL_01902 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NPEIKGBL_01903 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPEIKGBL_01904 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
NPEIKGBL_01905 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPEIKGBL_01906 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
NPEIKGBL_01907 2.8e-235 ytnL 3.5.1.47 E hydrolase activity
NPEIKGBL_01908 1.9e-156 ytnM S membrane transporter protein
NPEIKGBL_01909 8e-241 ytoI K transcriptional regulator containing CBS domains
NPEIKGBL_01910 3.1e-47 ytpI S YtpI-like protein
NPEIKGBL_01911 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NPEIKGBL_01912 9.2e-29
NPEIKGBL_01913 8.2e-69 ytrI
NPEIKGBL_01914 3.2e-56 ytrH S Sporulation protein YtrH
NPEIKGBL_01915 0.0 dnaE 2.7.7.7 L DNA polymerase
NPEIKGBL_01916 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NPEIKGBL_01917 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NPEIKGBL_01918 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NPEIKGBL_01919 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NPEIKGBL_01920 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NPEIKGBL_01921 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NPEIKGBL_01922 2.6e-192 ytvI S sporulation integral membrane protein YtvI
NPEIKGBL_01923 1.1e-70 yeaL S membrane
NPEIKGBL_01924 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NPEIKGBL_01925 1.8e-242 icd 1.1.1.42 C isocitrate
NPEIKGBL_01926 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NPEIKGBL_01927 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEIKGBL_01928 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NPEIKGBL_01929 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPEIKGBL_01930 1.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPEIKGBL_01931 1.1e-107 ytaF P Probably functions as a manganese efflux pump
NPEIKGBL_01932 4.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPEIKGBL_01933 8.9e-161 ytbE S reductase
NPEIKGBL_01934 7.3e-201 ytbD EGP Major facilitator Superfamily
NPEIKGBL_01935 9.9e-67 ytcD K Transcriptional regulator
NPEIKGBL_01936 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPEIKGBL_01937 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NPEIKGBL_01938 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPEIKGBL_01939 7.7e-266 dnaB L Membrane attachment protein
NPEIKGBL_01940 6.6e-173 dnaI L Primosomal protein DnaI
NPEIKGBL_01941 1.1e-110 ytxB S SNARE associated Golgi protein
NPEIKGBL_01942 1.4e-158 ytxC S YtxC-like family
NPEIKGBL_01944 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPEIKGBL_01945 2.8e-148 ysaA S HAD-hyrolase-like
NPEIKGBL_01946 0.0 lytS 2.7.13.3 T Histidine kinase
NPEIKGBL_01947 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
NPEIKGBL_01948 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NPEIKGBL_01949 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NPEIKGBL_01951 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPEIKGBL_01952 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NPEIKGBL_01953 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPEIKGBL_01954 7.5e-45 ysdA S Membrane
NPEIKGBL_01955 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NPEIKGBL_01956 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
NPEIKGBL_01957 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NPEIKGBL_01958 2.7e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NPEIKGBL_01959 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NPEIKGBL_01960 1.9e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NPEIKGBL_01961 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NPEIKGBL_01962 8.3e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NPEIKGBL_01963 6.2e-254 araN G carbohydrate transport
NPEIKGBL_01964 2.7e-166 araP G carbohydrate transport
NPEIKGBL_01965 3.4e-144 araQ G transport system permease
NPEIKGBL_01966 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NPEIKGBL_01967 0.0 cstA T Carbon starvation protein
NPEIKGBL_01968 4.5e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
NPEIKGBL_01969 3.1e-256 glcF C Glycolate oxidase
NPEIKGBL_01970 4.7e-263 glcD 1.1.3.15 C Glycolate oxidase subunit
NPEIKGBL_01971 2.7e-205 ysfB KT regulator
NPEIKGBL_01972 5.8e-32 sspI S Belongs to the SspI family
NPEIKGBL_01973 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPEIKGBL_01974 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPEIKGBL_01975 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPEIKGBL_01976 1.3e-165 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPEIKGBL_01977 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NPEIKGBL_01978 1.3e-85 cvpA S membrane protein, required for colicin V production
NPEIKGBL_01979 0.0 polX L COG1796 DNA polymerase IV (family X)
NPEIKGBL_01980 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPEIKGBL_01981 7.3e-68 yshE S membrane
NPEIKGBL_01982 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NPEIKGBL_01983 2.7e-100 fadR K Transcriptional regulator
NPEIKGBL_01984 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NPEIKGBL_01985 1.2e-135 etfB C Electron transfer flavoprotein
NPEIKGBL_01986 1.2e-177 etfA C Electron transfer flavoprotein
NPEIKGBL_01987 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NPEIKGBL_01988 2e-52 trxA O Belongs to the thioredoxin family
NPEIKGBL_01989 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPEIKGBL_01990 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NPEIKGBL_01991 1.2e-79 yslB S Protein of unknown function (DUF2507)
NPEIKGBL_01992 2.4e-107 sdhC C succinate dehydrogenase
NPEIKGBL_01993 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NPEIKGBL_01994 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NPEIKGBL_01995 1.9e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NPEIKGBL_01996 3.3e-30 gerE K Transcriptional regulator
NPEIKGBL_01997 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NPEIKGBL_01998 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NPEIKGBL_01999 6.5e-196 gerM S COG5401 Spore germination protein
NPEIKGBL_02000 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NPEIKGBL_02001 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPEIKGBL_02002 1.4e-92 ysnB S Phosphoesterase
NPEIKGBL_02004 2e-133 ysnF S protein conserved in bacteria
NPEIKGBL_02005 1.9e-77 ysnE K acetyltransferase
NPEIKGBL_02006 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NPEIKGBL_02007 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
NPEIKGBL_02008 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NPEIKGBL_02009 7.1e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NPEIKGBL_02010 1.3e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NPEIKGBL_02011 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NPEIKGBL_02012 1.5e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NPEIKGBL_02013 5.1e-187 ysoA H Tetratricopeptide repeat
NPEIKGBL_02014 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPEIKGBL_02015 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPEIKGBL_02016 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NPEIKGBL_02017 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NPEIKGBL_02018 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NPEIKGBL_02019 7e-89 ysxD
NPEIKGBL_02020 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NPEIKGBL_02021 3.6e-146 hemX O cytochrome C
NPEIKGBL_02022 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NPEIKGBL_02023 1.2e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NPEIKGBL_02024 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
NPEIKGBL_02025 7.3e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NPEIKGBL_02026 1.6e-217 spoVID M stage VI sporulation protein D
NPEIKGBL_02027 2.9e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NPEIKGBL_02028 1.6e-25
NPEIKGBL_02029 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPEIKGBL_02030 2.8e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NPEIKGBL_02031 3.3e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NPEIKGBL_02032 4.1e-165 spoIIB S Sporulation related domain
NPEIKGBL_02033 1.1e-101 maf D septum formation protein Maf
NPEIKGBL_02034 5.9e-126 radC E Belongs to the UPF0758 family
NPEIKGBL_02035 1.8e-184 mreB D Rod shape-determining protein MreB
NPEIKGBL_02036 2.8e-157 mreC M Involved in formation and maintenance of cell shape
NPEIKGBL_02037 1.4e-84 mreD M shape-determining protein
NPEIKGBL_02038 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NPEIKGBL_02039 4.7e-143 minD D Belongs to the ParA family
NPEIKGBL_02040 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NPEIKGBL_02041 9.2e-161 spoIVFB S Stage IV sporulation protein
NPEIKGBL_02042 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NPEIKGBL_02043 4.1e-56 ysxB J ribosomal protein
NPEIKGBL_02044 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NPEIKGBL_02045 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NPEIKGBL_02046 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPEIKGBL_02047 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NPEIKGBL_02048 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
NPEIKGBL_02049 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
NPEIKGBL_02050 1.3e-229 nifS 2.8.1.7 E Cysteine desulfurase
NPEIKGBL_02051 2e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NPEIKGBL_02052 2.7e-160 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NPEIKGBL_02053 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NPEIKGBL_02054 1.7e-157 safA M spore coat assembly protein SafA
NPEIKGBL_02055 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPEIKGBL_02056 3.6e-126 yebC K transcriptional regulatory protein
NPEIKGBL_02057 4.5e-261 alsT E Sodium alanine symporter
NPEIKGBL_02058 3.1e-51 S Family of unknown function (DUF5412)
NPEIKGBL_02060 4.7e-117 yrzF T serine threonine protein kinase
NPEIKGBL_02061 2.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NPEIKGBL_02062 5.3e-253 csbX EGP Major facilitator Superfamily
NPEIKGBL_02063 4.8e-93 bofC S BofC C-terminal domain
NPEIKGBL_02064 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPEIKGBL_02065 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPEIKGBL_02066 2.6e-18 yrzS S Protein of unknown function (DUF2905)
NPEIKGBL_02067 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NPEIKGBL_02068 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NPEIKGBL_02069 1.1e-38 yajC U Preprotein translocase subunit YajC
NPEIKGBL_02070 3.2e-72 yrzE S Protein of unknown function (DUF3792)
NPEIKGBL_02071 1.7e-111 yrbG S membrane
NPEIKGBL_02072 6.9e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPEIKGBL_02073 1.6e-48 yrzD S Post-transcriptional regulator
NPEIKGBL_02074 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NPEIKGBL_02075 2.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NPEIKGBL_02076 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NPEIKGBL_02077 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NPEIKGBL_02078 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPEIKGBL_02079 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPEIKGBL_02080 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPEIKGBL_02081 3.4e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
NPEIKGBL_02083 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NPEIKGBL_02084 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NPEIKGBL_02085 1.7e-134 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NPEIKGBL_02086 7.4e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NPEIKGBL_02087 1.2e-70 cymR K Transcriptional regulator
NPEIKGBL_02088 1.5e-211 iscS 2.8.1.7 E Cysteine desulfurase
NPEIKGBL_02089 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPEIKGBL_02090 1.4e-15 S COG0457 FOG TPR repeat
NPEIKGBL_02091 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPEIKGBL_02092 3e-81 yrrD S protein conserved in bacteria
NPEIKGBL_02093 9.8e-31 yrzR
NPEIKGBL_02094 8e-08 S Protein of unknown function (DUF3918)
NPEIKGBL_02095 2.2e-106 glnP P ABC transporter
NPEIKGBL_02096 1.2e-107 gluC P ABC transporter
NPEIKGBL_02097 4.3e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
NPEIKGBL_02098 5.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NPEIKGBL_02099 3e-169 yrrI S AI-2E family transporter
NPEIKGBL_02100 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPEIKGBL_02101 1.7e-41 yrzL S Belongs to the UPF0297 family
NPEIKGBL_02102 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPEIKGBL_02103 1.2e-45 yrzB S Belongs to the UPF0473 family
NPEIKGBL_02104 1.8e-182 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NPEIKGBL_02105 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
NPEIKGBL_02106 4.3e-172 yegQ O Peptidase U32
NPEIKGBL_02107 7.9e-246 yegQ O COG0826 Collagenase and related proteases
NPEIKGBL_02108 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NPEIKGBL_02109 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPEIKGBL_02110 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NPEIKGBL_02111 4.2e-63 yrrS S Protein of unknown function (DUF1510)
NPEIKGBL_02112 1.3e-25 yrzA S Protein of unknown function (DUF2536)
NPEIKGBL_02113 1.7e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NPEIKGBL_02114 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPEIKGBL_02115 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NPEIKGBL_02116 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NPEIKGBL_02117 4.6e-35 yrhC S YrhC-like protein
NPEIKGBL_02118 4.1e-78 yrhD S Protein of unknown function (DUF1641)
NPEIKGBL_02119 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NPEIKGBL_02120 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
NPEIKGBL_02121 1.8e-142 focA P Formate nitrite
NPEIKGBL_02124 1.4e-95 yrhH Q methyltransferase
NPEIKGBL_02125 1.8e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NPEIKGBL_02126 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NPEIKGBL_02127 1.3e-45 yrhK S YrhK-like protein
NPEIKGBL_02128 0.0 yrhL I Acyltransferase family
NPEIKGBL_02129 2.1e-149 rsiV S Protein of unknown function (DUF3298)
NPEIKGBL_02130 1.2e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NPEIKGBL_02131 3.5e-149 yrhO K Archaeal transcriptional regulator TrmB
NPEIKGBL_02132 3.6e-106 yrhP E LysE type translocator
NPEIKGBL_02133 1.5e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NPEIKGBL_02134 0.0 levR K PTS system fructose IIA component
NPEIKGBL_02135 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
NPEIKGBL_02136 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NPEIKGBL_02137 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NPEIKGBL_02138 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NPEIKGBL_02139 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NPEIKGBL_02140 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
NPEIKGBL_02141 1.8e-198 adhA 1.1.1.1 C alcohol dehydrogenase
NPEIKGBL_02142 1.2e-28 yphJ 4.1.1.44 S peroxiredoxin activity
NPEIKGBL_02143 4.3e-47 yraB K helix_turn_helix, mercury resistance
NPEIKGBL_02144 1.1e-49 yraD M Spore coat protein
NPEIKGBL_02145 1.3e-25 yraE
NPEIKGBL_02146 1.4e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NPEIKGBL_02147 3.2e-62 yraF M Spore coat protein
NPEIKGBL_02148 1.5e-36 yraG
NPEIKGBL_02149 8.5e-66 E Glyoxalase-like domain
NPEIKGBL_02150 3.4e-61 T sh3 domain protein
NPEIKGBL_02151 1.7e-60 T sh3 domain protein
NPEIKGBL_02152 2.8e-151 S Alpha beta hydrolase
NPEIKGBL_02153 6.4e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEIKGBL_02154 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NPEIKGBL_02155 1e-204 yraM S PrpF protein
NPEIKGBL_02156 1.2e-163 yraN K Transcriptional regulator
NPEIKGBL_02157 2.8e-225 yraO C Citrate transporter
NPEIKGBL_02158 1.7e-187 yrpG C Aldo/keto reductase family
NPEIKGBL_02159 3.5e-94 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NPEIKGBL_02160 7.8e-116 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NPEIKGBL_02162 1.6e-123 yrpD S Domain of unknown function, YrpD
NPEIKGBL_02163 1.8e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NPEIKGBL_02165 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NPEIKGBL_02166 9.3e-166 aadK G Streptomycin adenylyltransferase
NPEIKGBL_02167 2.7e-88 yrdA S DinB family
NPEIKGBL_02168 4.4e-54 S Protein of unknown function (DUF2568)
NPEIKGBL_02169 1e-99 yrdC 3.5.1.19 Q Isochorismatase family
NPEIKGBL_02171 1.2e-230 cypA C Cytochrome P450
NPEIKGBL_02172 8.3e-24 yrdF K ribonuclease inhibitor
NPEIKGBL_02173 1.1e-78 bkdR K helix_turn_helix ASNC type
NPEIKGBL_02174 2.8e-137 azlC E AzlC protein
NPEIKGBL_02175 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NPEIKGBL_02176 3.3e-226 brnQ E Component of the transport system for branched-chain amino acids
NPEIKGBL_02177 5e-162 gltR K LysR substrate binding domain
NPEIKGBL_02178 3.2e-65 yodA S tautomerase
NPEIKGBL_02179 2.2e-147 czcD P COG1230 Co Zn Cd efflux system component
NPEIKGBL_02180 1e-198 trkA P Oxidoreductase
NPEIKGBL_02181 1e-159 yrdQ K Transcriptional regulator
NPEIKGBL_02182 1.2e-169 yrdR EG EamA-like transporter family
NPEIKGBL_02183 3.9e-16 S YrzO-like protein
NPEIKGBL_02184 1.9e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NPEIKGBL_02185 5.9e-82 bltD 2.3.1.57 K FR47-like protein
NPEIKGBL_02186 1.1e-209 blt EGP Major facilitator Superfamily
NPEIKGBL_02187 3.8e-148 bltR K helix_turn_helix, mercury resistance
NPEIKGBL_02188 2.2e-107 yrkC G Cupin domain
NPEIKGBL_02189 7.8e-39 yrkD S protein conserved in bacteria
NPEIKGBL_02190 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
NPEIKGBL_02191 3.5e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
NPEIKGBL_02193 1.3e-204 yrkH P Rhodanese Homology Domain
NPEIKGBL_02194 3.5e-35 yrkI O Belongs to the sulfur carrier protein TusA family
NPEIKGBL_02195 4.3e-117 yrkJ S membrane transporter protein
NPEIKGBL_02196 2.8e-79 S Protein of unknown function with HXXEE motif
NPEIKGBL_02197 1.5e-97 ywrO S Flavodoxin-like fold
NPEIKGBL_02198 6e-105 yrkN K Acetyltransferase (GNAT) family
NPEIKGBL_02199 8.2e-224 yrkO P Protein of unknown function (DUF418)
NPEIKGBL_02200 1.1e-127 T Transcriptional regulator
NPEIKGBL_02201 9e-237 yrkQ T Histidine kinase
NPEIKGBL_02202 2e-68 psiE S Protein PsiE homolog
NPEIKGBL_02203 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEIKGBL_02204 3.2e-100 yqaB E IrrE N-terminal-like domain
NPEIKGBL_02206 1.9e-95 adk 2.7.4.3 F adenylate kinase activity
NPEIKGBL_02207 7.9e-89 K Transcriptional regulator PadR-like family
NPEIKGBL_02208 2.2e-159 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
NPEIKGBL_02210 1.3e-38 xkdC L IstB-like ATP binding protein
NPEIKGBL_02214 3.2e-40 L Transposase
NPEIKGBL_02215 3.7e-26 cotD S Inner spore coat protein D
NPEIKGBL_02217 3.4e-48 yqaS L DNA packaging
NPEIKGBL_02218 1.3e-27 S phage terminase, large subunit
NPEIKGBL_02219 6.8e-128 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NPEIKGBL_02220 9.2e-56 V HNH endonuclease
NPEIKGBL_02221 2.1e-70 yokH G SMI1 / KNR4 family
NPEIKGBL_02222 1.3e-25 S SMI1-KNR4 cell-wall
NPEIKGBL_02223 3.5e-162 yobL S Bacterial EndoU nuclease
NPEIKGBL_02224 7.6e-28
NPEIKGBL_02226 3.3e-65 S response regulator aspartate phosphatase
NPEIKGBL_02227 4.6e-140 yhfP 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
NPEIKGBL_02228 4.2e-64 K BetI-type transcriptional repressor, C-terminal
NPEIKGBL_02229 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEIKGBL_02230 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
NPEIKGBL_02231 2.3e-133 yqeB
NPEIKGBL_02232 1.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NPEIKGBL_02233 4.7e-106 yqeD S SNARE associated Golgi protein
NPEIKGBL_02234 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NPEIKGBL_02235 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
NPEIKGBL_02237 5.3e-95 yqeG S hydrolase of the HAD superfamily
NPEIKGBL_02238 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NPEIKGBL_02239 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NPEIKGBL_02240 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NPEIKGBL_02241 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPEIKGBL_02242 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NPEIKGBL_02243 3.8e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPEIKGBL_02244 6.5e-139 yqeM Q Methyltransferase
NPEIKGBL_02245 1.9e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPEIKGBL_02246 8.7e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NPEIKGBL_02247 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
NPEIKGBL_02248 0.0 comEC S Competence protein ComEC
NPEIKGBL_02249 4.1e-15 S YqzM-like protein
NPEIKGBL_02250 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
NPEIKGBL_02251 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
NPEIKGBL_02252 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NPEIKGBL_02253 2e-222 spoIIP M stage II sporulation protein P
NPEIKGBL_02254 7.2e-53 yqxA S Protein of unknown function (DUF3679)
NPEIKGBL_02255 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPEIKGBL_02256 2.6e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
NPEIKGBL_02257 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPEIKGBL_02258 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPEIKGBL_02259 0.0 dnaK O Heat shock 70 kDa protein
NPEIKGBL_02260 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPEIKGBL_02261 4.6e-174 prmA J Methylates ribosomal protein L11
NPEIKGBL_02262 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NPEIKGBL_02263 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NPEIKGBL_02264 1.4e-157 yqeW P COG1283 Na phosphate symporter
NPEIKGBL_02265 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NPEIKGBL_02266 2.5e-61 yqeY S Yqey-like protein
NPEIKGBL_02267 4.5e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NPEIKGBL_02268 3.7e-121 yqfA S UPF0365 protein
NPEIKGBL_02269 1e-24 yqfB
NPEIKGBL_02270 2.7e-45 yqfC S sporulation protein YqfC
NPEIKGBL_02271 2.1e-184 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NPEIKGBL_02272 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
NPEIKGBL_02274 0.0 yqfF S membrane-associated HD superfamily hydrolase
NPEIKGBL_02275 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPEIKGBL_02276 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NPEIKGBL_02277 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NPEIKGBL_02278 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPEIKGBL_02279 8.4e-19 S YqzL-like protein
NPEIKGBL_02280 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
NPEIKGBL_02281 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NPEIKGBL_02282 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NPEIKGBL_02283 4.5e-112 ccpN K CBS domain
NPEIKGBL_02284 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NPEIKGBL_02285 4.5e-88 yaiI S Belongs to the UPF0178 family
NPEIKGBL_02286 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPEIKGBL_02287 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPEIKGBL_02288 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NPEIKGBL_02289 3e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
NPEIKGBL_02290 1.5e-208 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPEIKGBL_02291 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NPEIKGBL_02292 3.6e-12 yqfQ S YqfQ-like protein
NPEIKGBL_02293 1.9e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPEIKGBL_02294 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NPEIKGBL_02295 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NPEIKGBL_02296 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NPEIKGBL_02297 4.2e-77 zur P Belongs to the Fur family
NPEIKGBL_02298 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NPEIKGBL_02299 2.8e-61 yqfX S membrane
NPEIKGBL_02300 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NPEIKGBL_02301 2.6e-46 yqfZ M LysM domain
NPEIKGBL_02302 3.9e-131 yqgB S Protein of unknown function (DUF1189)
NPEIKGBL_02303 4e-73 yqgC S protein conserved in bacteria
NPEIKGBL_02304 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NPEIKGBL_02305 2.5e-231 yqgE EGP Major facilitator superfamily
NPEIKGBL_02306 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NPEIKGBL_02307 1.7e-149 pstS P Phosphate
NPEIKGBL_02308 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NPEIKGBL_02309 2.2e-157 pstA P Phosphate transport system permease
NPEIKGBL_02310 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPEIKGBL_02311 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPEIKGBL_02312 9.5e-72 yqzC S YceG-like family
NPEIKGBL_02313 9.2e-51 yqzD
NPEIKGBL_02315 2.4e-198 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NPEIKGBL_02316 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NPEIKGBL_02317 5.7e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPEIKGBL_02318 2.5e-09 yqgO
NPEIKGBL_02319 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NPEIKGBL_02320 3.1e-33 yqgQ S Protein conserved in bacteria
NPEIKGBL_02321 3.4e-180 glcK 2.7.1.2 G Glucokinase
NPEIKGBL_02322 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NPEIKGBL_02323 1.1e-219 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NPEIKGBL_02324 3e-198 yqgU
NPEIKGBL_02325 6.9e-50 yqgV S Thiamine-binding protein
NPEIKGBL_02326 2e-22 yqgW S Protein of unknown function (DUF2759)
NPEIKGBL_02327 4.7e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NPEIKGBL_02328 1.8e-37 yqgY S Protein of unknown function (DUF2626)
NPEIKGBL_02329 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NPEIKGBL_02331 3.2e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPEIKGBL_02332 4.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NPEIKGBL_02333 4e-173 corA P Mg2 transporter protein
NPEIKGBL_02336 1.1e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NPEIKGBL_02337 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
NPEIKGBL_02338 1.4e-47 comGC U Required for transformation and DNA binding
NPEIKGBL_02339 1.2e-68 gspH NU protein transport across the cell outer membrane
NPEIKGBL_02340 7.6e-58 comGE
NPEIKGBL_02341 1.3e-34 comGF U Putative Competence protein ComGF
NPEIKGBL_02342 3.4e-43 S ComG operon protein 7
NPEIKGBL_02343 3.1e-26 yqzE S YqzE-like protein
NPEIKGBL_02344 7.3e-54 yqzG S Protein of unknown function (DUF3889)
NPEIKGBL_02345 6.7e-115 yqxM
NPEIKGBL_02346 1.9e-58 sipW 3.4.21.89 U Signal peptidase
NPEIKGBL_02347 2.5e-141 tasA S Cell division protein FtsN
NPEIKGBL_02348 1e-54 sinR K transcriptional
NPEIKGBL_02349 1.2e-24 sinI S Anti-repressor SinI
NPEIKGBL_02350 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
NPEIKGBL_02351 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NPEIKGBL_02352 5.3e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NPEIKGBL_02353 2.2e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NPEIKGBL_02354 1.5e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NPEIKGBL_02355 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
NPEIKGBL_02356 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NPEIKGBL_02357 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NPEIKGBL_02358 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
NPEIKGBL_02359 2.2e-61 yqhP
NPEIKGBL_02360 3e-173 yqhQ S Protein of unknown function (DUF1385)
NPEIKGBL_02361 3e-93 yqhR S Conserved membrane protein YqhR
NPEIKGBL_02362 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NPEIKGBL_02363 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NPEIKGBL_02364 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPEIKGBL_02365 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NPEIKGBL_02366 1.2e-171 spoIIIAA S stage III sporulation protein AA
NPEIKGBL_02367 3.2e-84 spoIIIAB S Stage III sporulation protein
NPEIKGBL_02368 7.6e-29 spoIIIAC S stage III sporulation protein AC
NPEIKGBL_02369 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NPEIKGBL_02370 2.9e-197 spoIIIAE S stage III sporulation protein AE
NPEIKGBL_02371 4.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NPEIKGBL_02372 8.5e-109 spoIIIAG S stage III sporulation protein AG
NPEIKGBL_02373 9.9e-91 spoIIIAH S SpoIIIAH-like protein
NPEIKGBL_02374 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NPEIKGBL_02375 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NPEIKGBL_02376 2.1e-67 yqhY S protein conserved in bacteria
NPEIKGBL_02377 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPEIKGBL_02378 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPEIKGBL_02379 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPEIKGBL_02380 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPEIKGBL_02381 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPEIKGBL_02382 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPEIKGBL_02383 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NPEIKGBL_02384 1.7e-78 argR K Regulates arginine biosynthesis genes
NPEIKGBL_02385 6.5e-307 recN L May be involved in recombinational repair of damaged DNA
NPEIKGBL_02386 1.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
NPEIKGBL_02387 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NPEIKGBL_02389 8e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NPEIKGBL_02390 6e-27
NPEIKGBL_02391 7.8e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NPEIKGBL_02392 2.6e-132 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NPEIKGBL_02393 3.5e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
NPEIKGBL_02394 2.6e-155 hbdA 1.1.1.157 I Dehydrogenase
NPEIKGBL_02395 2e-211 mmgC I acyl-CoA dehydrogenase
NPEIKGBL_02396 1.3e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NPEIKGBL_02397 1.8e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NPEIKGBL_02398 1e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NPEIKGBL_02399 4e-34 yqzF S Protein of unknown function (DUF2627)
NPEIKGBL_02400 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NPEIKGBL_02401 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NPEIKGBL_02402 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NPEIKGBL_02403 2.7e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NPEIKGBL_02404 9.8e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NPEIKGBL_02405 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NPEIKGBL_02406 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPEIKGBL_02407 1.3e-227 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPEIKGBL_02408 2.6e-152 bmrR K helix_turn_helix, mercury resistance
NPEIKGBL_02409 5.1e-207 norA EGP Major facilitator Superfamily
NPEIKGBL_02410 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NPEIKGBL_02411 9.3e-77 yqiW S Belongs to the UPF0403 family
NPEIKGBL_02412 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
NPEIKGBL_02413 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NPEIKGBL_02414 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NPEIKGBL_02415 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
NPEIKGBL_02416 4e-98 yqjB S protein conserved in bacteria
NPEIKGBL_02418 2.3e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NPEIKGBL_02419 5.9e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NPEIKGBL_02420 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NPEIKGBL_02421 1.1e-138 yqjF S Uncharacterized conserved protein (COG2071)
NPEIKGBL_02422 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPEIKGBL_02423 4.5e-24 yqzJ
NPEIKGBL_02424 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPEIKGBL_02425 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPEIKGBL_02426 2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NPEIKGBL_02427 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPEIKGBL_02428 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NPEIKGBL_02429 2.6e-143 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NPEIKGBL_02430 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NPEIKGBL_02431 0.0 rocB E arginine degradation protein
NPEIKGBL_02432 7.3e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPEIKGBL_02433 1.3e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NPEIKGBL_02434 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEIKGBL_02435 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NPEIKGBL_02436 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
NPEIKGBL_02437 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEIKGBL_02439 5.2e-226 yqjV G Major Facilitator Superfamily
NPEIKGBL_02441 5.4e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPEIKGBL_02442 1.7e-49 S YolD-like protein
NPEIKGBL_02443 3.6e-87 yqjY K acetyltransferase
NPEIKGBL_02444 1.6e-55 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NPEIKGBL_02445 2.2e-193 yqkA K GrpB protein
NPEIKGBL_02446 1.1e-53 yqkB S Belongs to the HesB IscA family
NPEIKGBL_02447 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NPEIKGBL_02448 2.1e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NPEIKGBL_02449 3.1e-12 yqkE S Protein of unknown function (DUF3886)
NPEIKGBL_02450 1.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NPEIKGBL_02452 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NPEIKGBL_02453 5.8e-219 yqxK 3.6.4.12 L DNA helicase
NPEIKGBL_02454 4.5e-58 ansR K Transcriptional regulator
NPEIKGBL_02455 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
NPEIKGBL_02456 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NPEIKGBL_02457 9.1e-235 mleN C Na H antiporter
NPEIKGBL_02458 5.5e-242 mleA 1.1.1.38 C malic enzyme
NPEIKGBL_02459 2.2e-31 yqkK
NPEIKGBL_02460 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NPEIKGBL_02461 2.4e-80 fur P Belongs to the Fur family
NPEIKGBL_02462 1.4e-36 S Protein of unknown function (DUF4227)
NPEIKGBL_02463 5.7e-166 xerD L recombinase XerD
NPEIKGBL_02464 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NPEIKGBL_02465 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NPEIKGBL_02466 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NPEIKGBL_02467 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NPEIKGBL_02468 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NPEIKGBL_02469 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEIKGBL_02470 9.6e-112 spoVAA S Stage V sporulation protein AA
NPEIKGBL_02471 1e-67 spoVAB S Stage V sporulation protein AB
NPEIKGBL_02472 2.3e-78 spoVAC S stage V sporulation protein AC
NPEIKGBL_02473 9e-192 spoVAD I Stage V sporulation protein AD
NPEIKGBL_02474 2.2e-57 spoVAEB S stage V sporulation protein
NPEIKGBL_02475 1.4e-110 spoVAEA S stage V sporulation protein
NPEIKGBL_02476 1.4e-273 spoVAF EG Stage V sporulation protein AF
NPEIKGBL_02477 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NPEIKGBL_02478 3.6e-149 ypuA S Secreted protein
NPEIKGBL_02479 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPEIKGBL_02483 5.6e-07
NPEIKGBL_02484 1.9e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPEIKGBL_02486 1e-07 eaeH M Domain of Unknown Function (DUF1259)
NPEIKGBL_02490 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NPEIKGBL_02491 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NPEIKGBL_02492 7.8e-55 ypuD
NPEIKGBL_02493 4.2e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NPEIKGBL_02494 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
NPEIKGBL_02495 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NPEIKGBL_02496 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NPEIKGBL_02497 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEIKGBL_02498 2.7e-91 ypuF S Domain of unknown function (DUF309)
NPEIKGBL_02499 1.4e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPEIKGBL_02500 3.5e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPEIKGBL_02501 7.6e-97 ypuI S Protein of unknown function (DUF3907)
NPEIKGBL_02502 1.8e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NPEIKGBL_02503 3.5e-103 spmA S Spore maturation protein
NPEIKGBL_02504 1.9e-87 spmB S Spore maturation protein
NPEIKGBL_02505 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPEIKGBL_02506 1.4e-98 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NPEIKGBL_02507 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NPEIKGBL_02508 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NPEIKGBL_02509 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEIKGBL_02510 0.0 resE 2.7.13.3 T Histidine kinase
NPEIKGBL_02511 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NPEIKGBL_02512 5.5e-187 rsiX
NPEIKGBL_02513 1e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NPEIKGBL_02514 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPEIKGBL_02515 2.2e-86 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPEIKGBL_02516 4.7e-41 fer C Ferredoxin
NPEIKGBL_02517 4.4e-197 ypbB 5.1.3.1 S protein conserved in bacteria
NPEIKGBL_02518 2.1e-285 recQ 3.6.4.12 L DNA helicase
NPEIKGBL_02519 1.1e-99 ypbD S metal-dependent membrane protease
NPEIKGBL_02520 6.9e-77 ypbE M Lysin motif
NPEIKGBL_02521 8.2e-81 ypbF S Protein of unknown function (DUF2663)
NPEIKGBL_02522 5.2e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
NPEIKGBL_02523 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NPEIKGBL_02524 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NPEIKGBL_02525 1.1e-173 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NPEIKGBL_02526 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
NPEIKGBL_02527 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NPEIKGBL_02528 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NPEIKGBL_02529 9.2e-113 ypfA M Flagellar protein YcgR
NPEIKGBL_02530 1.8e-23 S Family of unknown function (DUF5359)
NPEIKGBL_02531 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NPEIKGBL_02532 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NPEIKGBL_02533 7.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPEIKGBL_02534 1.4e-07 S YpzI-like protein
NPEIKGBL_02535 1.3e-102 yphA
NPEIKGBL_02536 2.5e-161 seaA S YIEGIA protein
NPEIKGBL_02537 1.6e-28 ypzH
NPEIKGBL_02538 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NPEIKGBL_02539 1.6e-180 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NPEIKGBL_02540 1.2e-18 yphE S Protein of unknown function (DUF2768)
NPEIKGBL_02541 6.6e-136 yphF
NPEIKGBL_02542 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NPEIKGBL_02543 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPEIKGBL_02544 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NPEIKGBL_02545 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NPEIKGBL_02546 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NPEIKGBL_02547 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NPEIKGBL_02548 9.9e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPEIKGBL_02549 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NPEIKGBL_02550 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NPEIKGBL_02551 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NPEIKGBL_02552 5.8e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NPEIKGBL_02553 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NPEIKGBL_02554 1.1e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NPEIKGBL_02555 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NPEIKGBL_02556 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NPEIKGBL_02557 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NPEIKGBL_02558 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NPEIKGBL_02559 8e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NPEIKGBL_02560 1.3e-201 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NPEIKGBL_02561 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NPEIKGBL_02562 1.1e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NPEIKGBL_02563 5.9e-233 S COG0457 FOG TPR repeat
NPEIKGBL_02564 2.8e-99 ypiB S Belongs to the UPF0302 family
NPEIKGBL_02565 1.6e-76 ypiF S Protein of unknown function (DUF2487)
NPEIKGBL_02566 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NPEIKGBL_02567 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NPEIKGBL_02568 1.3e-145 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NPEIKGBL_02569 4.9e-97 ypjA S membrane
NPEIKGBL_02570 6.1e-143 ypjB S sporulation protein
NPEIKGBL_02571 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NPEIKGBL_02572 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NPEIKGBL_02573 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NPEIKGBL_02574 7.9e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NPEIKGBL_02575 1.7e-128 bshB1 S proteins, LmbE homologs
NPEIKGBL_02576 1.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NPEIKGBL_02577 2e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPEIKGBL_02578 9.6e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPEIKGBL_02579 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NPEIKGBL_02580 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NPEIKGBL_02581 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NPEIKGBL_02582 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NPEIKGBL_02583 1.9e-22 ypmA S Protein of unknown function (DUF4264)
NPEIKGBL_02584 3.4e-80 ypmB S protein conserved in bacteria
NPEIKGBL_02585 2.2e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NPEIKGBL_02586 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NPEIKGBL_02587 5.7e-129 dnaD L DNA replication protein DnaD
NPEIKGBL_02588 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NPEIKGBL_02589 1.8e-92 ypoC
NPEIKGBL_02590 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NPEIKGBL_02591 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPEIKGBL_02592 2.2e-187 yppC S Protein of unknown function (DUF2515)
NPEIKGBL_02595 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
NPEIKGBL_02597 1.2e-48 yppG S YppG-like protein
NPEIKGBL_02598 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
NPEIKGBL_02599 1e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NPEIKGBL_02600 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NPEIKGBL_02601 1.5e-236 yprB L RNase_H superfamily
NPEIKGBL_02602 9.7e-92 ypsA S Belongs to the UPF0398 family
NPEIKGBL_02603 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPEIKGBL_02604 1.7e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NPEIKGBL_02606 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NPEIKGBL_02607 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEIKGBL_02608 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NPEIKGBL_02609 4.1e-184 ptxS K transcriptional
NPEIKGBL_02610 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NPEIKGBL_02611 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NPEIKGBL_02612 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NPEIKGBL_02613 4.6e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NPEIKGBL_02614 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPEIKGBL_02615 2.1e-225 pbuX F xanthine
NPEIKGBL_02616 9.1e-206 bcsA Q Naringenin-chalcone synthase
NPEIKGBL_02617 5.1e-87 ypbQ S protein conserved in bacteria
NPEIKGBL_02618 0.0 ypbR S Dynamin family
NPEIKGBL_02619 1e-38 ypbS S Protein of unknown function (DUF2533)
NPEIKGBL_02620 2e-07
NPEIKGBL_02621 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
NPEIKGBL_02623 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
NPEIKGBL_02624 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NPEIKGBL_02625 4.4e-126 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NPEIKGBL_02626 3e-29 ypeQ S Zinc-finger
NPEIKGBL_02627 8.1e-31 S Protein of unknown function (DUF2564)
NPEIKGBL_02628 3.8e-16 degR
NPEIKGBL_02629 7.9e-31 cspD K Cold-shock protein
NPEIKGBL_02630 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NPEIKGBL_02632 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NPEIKGBL_02633 1.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NPEIKGBL_02634 7.9e-106 ypgQ S phosphohydrolase
NPEIKGBL_02635 5.8e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
NPEIKGBL_02636 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NPEIKGBL_02637 1.7e-75 yphP S Belongs to the UPF0403 family
NPEIKGBL_02638 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NPEIKGBL_02639 7.8e-114 ypjP S YpjP-like protein
NPEIKGBL_02640 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NPEIKGBL_02641 2.1e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPEIKGBL_02642 5.1e-95 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPEIKGBL_02643 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NPEIKGBL_02644 4.2e-110 hlyIII S protein, Hemolysin III
NPEIKGBL_02645 1.6e-185 pspF K Transcriptional regulator
NPEIKGBL_02646 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NPEIKGBL_02647 3.1e-40 ypmP S Protein of unknown function (DUF2535)
NPEIKGBL_02648 3.5e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NPEIKGBL_02649 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
NPEIKGBL_02650 5e-99 ypmS S protein conserved in bacteria
NPEIKGBL_02651 5.5e-29 ypmT S Uncharacterized ympT
NPEIKGBL_02652 2.7e-220 mepA V MATE efflux family protein
NPEIKGBL_02653 1.6e-70 ypoP K transcriptional
NPEIKGBL_02654 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPEIKGBL_02655 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NPEIKGBL_02656 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
NPEIKGBL_02657 1.3e-207 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NPEIKGBL_02658 2.2e-187 cgeB S Spore maturation protein
NPEIKGBL_02659 1.2e-65 cgeA
NPEIKGBL_02660 3.5e-38 cgeC
NPEIKGBL_02661 1.9e-255 cgeD M maturation of the outermost layer of the spore
NPEIKGBL_02662 2.7e-143 yiiD K acetyltransferase
NPEIKGBL_02664 1.4e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPEIKGBL_02665 4.2e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NPEIKGBL_02666 2.8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NPEIKGBL_02667 9.3e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
NPEIKGBL_02668 6.7e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NPEIKGBL_02669 5.1e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
NPEIKGBL_02670 2.9e-47 yokU S YokU-like protein, putative antitoxin
NPEIKGBL_02671 1.4e-36 yozE S Belongs to the UPF0346 family
NPEIKGBL_02672 1.6e-123 yodN
NPEIKGBL_02674 2.8e-24 yozD S YozD-like protein
NPEIKGBL_02675 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
NPEIKGBL_02676 3.6e-54 yodL S YodL-like
NPEIKGBL_02677 5.3e-09
NPEIKGBL_02678 9.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NPEIKGBL_02679 1.4e-134 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NPEIKGBL_02680 6.8e-24 yodI
NPEIKGBL_02681 6.3e-128 yodH Q Methyltransferase
NPEIKGBL_02682 5.9e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NPEIKGBL_02683 1.9e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPEIKGBL_02684 6.2e-28 S Protein of unknown function (DUF3311)
NPEIKGBL_02685 1.1e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
NPEIKGBL_02686 1.2e-111 mhqD S Carboxylesterase
NPEIKGBL_02687 1.4e-107 yodC C nitroreductase
NPEIKGBL_02688 4.4e-55 yodB K transcriptional
NPEIKGBL_02689 8e-64 yodA S tautomerase
NPEIKGBL_02690 4.2e-205 gntP EG COG2610 H gluconate symporter and related permeases
NPEIKGBL_02691 3.4e-09
NPEIKGBL_02692 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
NPEIKGBL_02693 5.6e-161 rarD S -transporter
NPEIKGBL_02694 1.5e-43
NPEIKGBL_02695 2.2e-60 yojF S Protein of unknown function (DUF1806)
NPEIKGBL_02696 2.1e-125 yojG S deacetylase
NPEIKGBL_02697 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPEIKGBL_02698 3.6e-244 norM V Multidrug efflux pump
NPEIKGBL_02700 7.6e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPEIKGBL_02701 5.3e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NPEIKGBL_02702 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NPEIKGBL_02703 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NPEIKGBL_02704 2.1e-160 yojN S ATPase family associated with various cellular activities (AAA)
NPEIKGBL_02705 0.0 yojO P Von Willebrand factor
NPEIKGBL_02706 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NPEIKGBL_02707 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NPEIKGBL_02708 1.1e-167 yocS S -transporter
NPEIKGBL_02709 4.5e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NPEIKGBL_02710 3.9e-164 sodA 1.15.1.1 P Superoxide dismutase
NPEIKGBL_02711 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NPEIKGBL_02712 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NPEIKGBL_02713 2.7e-31 yozC
NPEIKGBL_02714 4.2e-56 yozO S Bacterial PH domain
NPEIKGBL_02715 1.9e-36 yocN
NPEIKGBL_02716 1.1e-40 yozN
NPEIKGBL_02717 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
NPEIKGBL_02718 2.8e-32
NPEIKGBL_02719 6.4e-54 yocL
NPEIKGBL_02720 3.3e-83 dksA T general stress protein
NPEIKGBL_02721 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NPEIKGBL_02722 0.0 recQ 3.6.4.12 L DNA helicase
NPEIKGBL_02723 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
NPEIKGBL_02724 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEIKGBL_02725 1.7e-196 desK 2.7.13.3 T Histidine kinase
NPEIKGBL_02726 1e-201 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NPEIKGBL_02727 3.2e-186 yocD 3.4.17.13 V peptidase S66
NPEIKGBL_02728 1.6e-93 yocC
NPEIKGBL_02729 6.4e-145
NPEIKGBL_02730 1.5e-92 yozB S membrane
NPEIKGBL_02731 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NPEIKGBL_02732 1e-51 czrA K transcriptional
NPEIKGBL_02733 8.8e-93 yobW
NPEIKGBL_02734 7.1e-175 yobV K WYL domain
NPEIKGBL_02735 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
NPEIKGBL_02736 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NPEIKGBL_02737 1.3e-97 yobS K Transcriptional regulator
NPEIKGBL_02738 4.5e-140 yobR 2.3.1.1 J FR47-like protein
NPEIKGBL_02739 3.8e-136 yobQ K helix_turn_helix, arabinose operon control protein
NPEIKGBL_02740 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NPEIKGBL_02741 1.3e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NPEIKGBL_02742 3.7e-102 yokH G SMI1 / KNR4 family
NPEIKGBL_02743 4.4e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NPEIKGBL_02744 6.9e-19
NPEIKGBL_02746 4.6e-96 S aspartate phosphatase
NPEIKGBL_02748 1.4e-33 yoqW S Belongs to the SOS response-associated peptidase family
NPEIKGBL_02749 3.6e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
NPEIKGBL_02750 1.7e-88
NPEIKGBL_02751 2.2e-120 isp O Subtilase family
NPEIKGBL_02753 6.5e-41
NPEIKGBL_02754 6.6e-71 O Torsin
NPEIKGBL_02756 4.6e-11 ywlA S Uncharacterised protein family (UPF0715)
NPEIKGBL_02759 4.4e-09
NPEIKGBL_02760 1.6e-21
NPEIKGBL_02762 5.1e-26
NPEIKGBL_02763 6.9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NPEIKGBL_02764 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NPEIKGBL_02767 8.5e-165 bla 3.5.2.6 V beta-lactamase
NPEIKGBL_02768 5.2e-113 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NPEIKGBL_02769 1.8e-77 yoaW
NPEIKGBL_02770 5.6e-158 yijE EG EamA-like transporter family
NPEIKGBL_02771 4.3e-158 yoaU K LysR substrate binding domain
NPEIKGBL_02772 4.1e-147 yoaT S Protein of unknown function (DUF817)
NPEIKGBL_02773 4.2e-37 yozG K Transcriptional regulator
NPEIKGBL_02774 2.1e-74 yoaS S Protein of unknown function (DUF2975)
NPEIKGBL_02775 2.4e-172 yoaR V vancomycin resistance protein
NPEIKGBL_02776 5e-87
NPEIKGBL_02777 5.9e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
NPEIKGBL_02778 1.9e-146 yoaP 3.1.3.18 K YoaP-like
NPEIKGBL_02780 3.5e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
NPEIKGBL_02782 3.5e-131 yoqW S Belongs to the SOS response-associated peptidase family
NPEIKGBL_02783 8.1e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NPEIKGBL_02784 2.9e-109 yoaK S Membrane
NPEIKGBL_02785 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NPEIKGBL_02786 1.8e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NPEIKGBL_02787 5.5e-178 mcpU NT methyl-accepting chemotaxis protein
NPEIKGBL_02788 1.3e-37 S Protein of unknown function (DUF4025)
NPEIKGBL_02789 2.6e-13
NPEIKGBL_02790 1.6e-07
NPEIKGBL_02791 3.3e-90 purR K Transcriptional regulator
NPEIKGBL_02792 3.2e-151 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
NPEIKGBL_02793 1.6e-205 S Oxidoreductase family, C-terminal alpha/beta domain
NPEIKGBL_02794 3e-172 iolT EGP Major facilitator Superfamily
NPEIKGBL_02795 6.6e-32 yoaF
NPEIKGBL_02796 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPEIKGBL_02797 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPEIKGBL_02798 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NPEIKGBL_02799 6.2e-235 yoaB EGP Major facilitator Superfamily
NPEIKGBL_02800 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NPEIKGBL_02801 3.1e-144 yoxB
NPEIKGBL_02802 9.8e-41 yoxC S Bacterial protein of unknown function (DUF948)
NPEIKGBL_02803 2.4e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEIKGBL_02804 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NPEIKGBL_02805 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPEIKGBL_02806 3.5e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPEIKGBL_02807 7.8e-155 gltC K Transcriptional regulator
NPEIKGBL_02808 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NPEIKGBL_02809 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NPEIKGBL_02810 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NPEIKGBL_02811 8e-157 gltR1 K Transcriptional regulator
NPEIKGBL_02812 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NPEIKGBL_02813 3e-34 yoeD G Helix-turn-helix domain
NPEIKGBL_02814 2.9e-96 L Integrase
NPEIKGBL_02816 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
NPEIKGBL_02817 2.3e-246 yoeA V MATE efflux family protein
NPEIKGBL_02818 3.4e-188 yoxA 5.1.3.3 G Aldose 1-epimerase
NPEIKGBL_02819 1.8e-270 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NPEIKGBL_02820 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEIKGBL_02821 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEIKGBL_02822 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEIKGBL_02823 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPEIKGBL_02824 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NPEIKGBL_02825 4e-63 yngL S Protein of unknown function (DUF1360)
NPEIKGBL_02826 4.5e-304 yngK T Glycosyl hydrolase-like 10
NPEIKGBL_02827 2.5e-206 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NPEIKGBL_02828 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NPEIKGBL_02829 8.6e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NPEIKGBL_02830 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NPEIKGBL_02831 1.5e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NPEIKGBL_02832 7.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NPEIKGBL_02833 1.3e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NPEIKGBL_02834 3.3e-233 nrnB S phosphohydrolase (DHH superfamily)
NPEIKGBL_02835 5.5e-104 yngC S membrane-associated protein
NPEIKGBL_02836 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NPEIKGBL_02837 1.6e-79 yngA S membrane
NPEIKGBL_02838 1.2e-296 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NPEIKGBL_02839 1.2e-249 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NPEIKGBL_02841 2.1e-293 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NPEIKGBL_02842 1.8e-251 agcS E Sodium alanine symporter
NPEIKGBL_02843 1.3e-57 ynfC
NPEIKGBL_02844 2.3e-12
NPEIKGBL_02845 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPEIKGBL_02846 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPEIKGBL_02847 6.6e-69 yccU S CoA-binding protein
NPEIKGBL_02848 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPEIKGBL_02849 4.1e-49 yneR S Belongs to the HesB IscA family
NPEIKGBL_02850 1.3e-53 yneQ
NPEIKGBL_02851 1.2e-73 yneP S Thioesterase-like superfamily
NPEIKGBL_02852 3.9e-35 tlp S Belongs to the Tlp family
NPEIKGBL_02853 3.1e-08 sspN S Small acid-soluble spore protein N family
NPEIKGBL_02855 5.9e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NPEIKGBL_02856 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NPEIKGBL_02857 2.2e-14 sspO S Belongs to the SspO family
NPEIKGBL_02858 3.9e-19 sspP S Belongs to the SspP family
NPEIKGBL_02859 2.2e-63 hspX O Spore coat protein
NPEIKGBL_02860 2.1e-73 yneK S Protein of unknown function (DUF2621)
NPEIKGBL_02861 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NPEIKGBL_02862 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NPEIKGBL_02863 7.1e-127 ccdA O cytochrome c biogenesis protein
NPEIKGBL_02864 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NPEIKGBL_02865 1.8e-28 yneF S UPF0154 protein
NPEIKGBL_02866 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NPEIKGBL_02867 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NPEIKGBL_02868 1.3e-32 ynzC S UPF0291 protein
NPEIKGBL_02869 4.5e-112 yneB L resolvase
NPEIKGBL_02870 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NPEIKGBL_02871 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NPEIKGBL_02872 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NPEIKGBL_02873 5.8e-74 yndM S Protein of unknown function (DUF2512)
NPEIKGBL_02874 2.1e-137 yndL S Replication protein
NPEIKGBL_02876 1e-306 yndJ S YndJ-like protein
NPEIKGBL_02877 1.4e-113 yndH S Domain of unknown function (DUF4166)
NPEIKGBL_02878 7.7e-154 yndG S DoxX-like family
NPEIKGBL_02879 4.2e-220 gerLC S Spore germination protein
NPEIKGBL_02880 1.7e-196 gerAB U Spore germination
NPEIKGBL_02881 2.1e-280 gerAA EG Spore germination protein
NPEIKGBL_02884 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NPEIKGBL_02885 1.8e-71
NPEIKGBL_02886 3.9e-24 tatA U protein secretion
NPEIKGBL_02889 1.1e-130 S Domain of unknown function, YrpD
NPEIKGBL_02891 1.2e-162 S Thymidylate synthase
NPEIKGBL_02894 5.2e-15
NPEIKGBL_02895 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NPEIKGBL_02896 6.3e-84 yncE S Protein of unknown function (DUF2691)
NPEIKGBL_02897 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPEIKGBL_02898 3.5e-247 iolT EGP Major facilitator Superfamily
NPEIKGBL_02899 3.4e-112 yokF 3.1.31.1 L RNA catabolic process
NPEIKGBL_02900 9.6e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NPEIKGBL_02901 6.4e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NPEIKGBL_02902 2.1e-213 xylR GK ROK family
NPEIKGBL_02903 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NPEIKGBL_02904 1.1e-253 xynT G MFS/sugar transport protein
NPEIKGBL_02905 6.9e-78 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NPEIKGBL_02907 1.3e-56 ynaF
NPEIKGBL_02908 4.9e-111 ynaE S Domain of unknown function (DUF3885)
NPEIKGBL_02909 5e-15 K Cro/C1-type HTH DNA-binding domain
NPEIKGBL_02910 6.1e-08 S Uncharacterised protein family (UPF0715)
NPEIKGBL_02911 2.8e-75 S CAAX protease self-immunity
NPEIKGBL_02913 1.3e-96 ynaD J Acetyltransferase (GNAT) domain
NPEIKGBL_02914 3.3e-141 ynaC
NPEIKGBL_02915 2.6e-89 G SMI1-KNR4 cell-wall
NPEIKGBL_02916 7e-37
NPEIKGBL_02917 3.7e-87
NPEIKGBL_02918 5.3e-16
NPEIKGBL_02919 2.9e-31
NPEIKGBL_02920 7.7e-11
NPEIKGBL_02924 2.9e-11 S Terminase
NPEIKGBL_02925 8e-53 L phage terminase small subunit
NPEIKGBL_02926 1.4e-09 L phage terminase small subunit
NPEIKGBL_02927 1.6e-43 T Histidine kinase
NPEIKGBL_02929 2.7e-30 D nuclear chromosome segregation
NPEIKGBL_02930 4.1e-266 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NPEIKGBL_02931 3.7e-52 S SMI1-KNR4 cell-wall
NPEIKGBL_02932 8.3e-103 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NPEIKGBL_02933 1.7e-23 S Pfam:Phage_holin_4_1
NPEIKGBL_02934 3.2e-15 S Bacteriophage holin family
NPEIKGBL_02935 1.1e-94 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
NPEIKGBL_02936 6.1e-62 L Belongs to the 'phage' integrase family
NPEIKGBL_02937 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
NPEIKGBL_02938 1.1e-68 glnR K transcriptional
NPEIKGBL_02939 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NPEIKGBL_02940 7.9e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NPEIKGBL_02941 8.6e-176 spoVK O stage V sporulation protein K
NPEIKGBL_02942 2.3e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NPEIKGBL_02943 2e-109 ymaB
NPEIKGBL_02944 1e-187 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPEIKGBL_02945 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPEIKGBL_02946 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NPEIKGBL_02947 4.5e-22 ymzA
NPEIKGBL_02948 8.2e-23
NPEIKGBL_02949 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NPEIKGBL_02950 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPEIKGBL_02951 2.1e-46 ymaF S YmaF family
NPEIKGBL_02953 4.9e-51 ebrA P Small Multidrug Resistance protein
NPEIKGBL_02954 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NPEIKGBL_02955 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
NPEIKGBL_02956 2.1e-126 ymaC S Replication protein
NPEIKGBL_02957 1.9e-07 K Transcriptional regulator
NPEIKGBL_02958 4.6e-252 aprX O Belongs to the peptidase S8 family
NPEIKGBL_02959 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
NPEIKGBL_02960 1.2e-61 ymzB
NPEIKGBL_02961 9.7e-233 cypA C Cytochrome P450
NPEIKGBL_02962 0.0 pks13 HQ Beta-ketoacyl synthase
NPEIKGBL_02963 0.0 dhbF IQ polyketide synthase
NPEIKGBL_02964 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
NPEIKGBL_02965 0.0 pfaA Q Polyketide synthase of type I
NPEIKGBL_02966 0.0 rhiB IQ polyketide synthase
NPEIKGBL_02967 5.7e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NPEIKGBL_02968 1e-142 pksH 4.2.1.18 I enoyl-CoA hydratase
NPEIKGBL_02969 3.9e-245 pksG 2.3.3.10 I synthase
NPEIKGBL_02970 1.3e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPEIKGBL_02971 1.4e-37 acpK IQ Phosphopantetheine attachment site
NPEIKGBL_02972 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NPEIKGBL_02973 5.1e-184 pksD Q Acyl transferase domain
NPEIKGBL_02975 7.5e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NPEIKGBL_02976 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
NPEIKGBL_02977 1.3e-108 pksA K Transcriptional regulator
NPEIKGBL_02978 5.1e-96 ymcC S Membrane
NPEIKGBL_02979 3.1e-70 S Regulatory protein YrvL
NPEIKGBL_02980 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPEIKGBL_02981 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPEIKGBL_02982 2.2e-88 cotE S Spore coat protein
NPEIKGBL_02983 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NPEIKGBL_02984 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NPEIKGBL_02985 4.7e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NPEIKGBL_02986 7.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NPEIKGBL_02987 1.2e-36 spoVS S Stage V sporulation protein S
NPEIKGBL_02988 1.9e-152 ymdB S protein conserved in bacteria
NPEIKGBL_02989 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NPEIKGBL_02990 1.3e-213 pbpX V Beta-lactamase
NPEIKGBL_02991 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPEIKGBL_02992 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
NPEIKGBL_02993 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPEIKGBL_02994 1.9e-124 ymfM S protein conserved in bacteria
NPEIKGBL_02995 2.7e-143 ymfK S Protein of unknown function (DUF3388)
NPEIKGBL_02996 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NPEIKGBL_02997 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NPEIKGBL_02998 3.5e-241 ymfH S zinc protease
NPEIKGBL_02999 1.1e-234 ymfF S Peptidase M16
NPEIKGBL_03000 1.5e-206 ymfD EGP Major facilitator Superfamily
NPEIKGBL_03001 1.4e-133 ymfC K Transcriptional regulator
NPEIKGBL_03002 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NPEIKGBL_03003 2.9e-31 S YlzJ-like protein
NPEIKGBL_03004 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NPEIKGBL_03005 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPEIKGBL_03006 1.5e-155 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NPEIKGBL_03007 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NPEIKGBL_03008 7.1e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NPEIKGBL_03009 6.3e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NPEIKGBL_03010 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NPEIKGBL_03011 2.6e-42 ymxH S YlmC YmxH family
NPEIKGBL_03012 4.4e-233 pepR S Belongs to the peptidase M16 family
NPEIKGBL_03013 5.7e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NPEIKGBL_03014 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NPEIKGBL_03015 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPEIKGBL_03016 8.8e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NPEIKGBL_03017 1.6e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPEIKGBL_03018 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPEIKGBL_03019 3e-44 ylxP S protein conserved in bacteria
NPEIKGBL_03020 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPEIKGBL_03021 3.1e-47 ylxQ J ribosomal protein
NPEIKGBL_03022 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NPEIKGBL_03023 1.1e-203 nusA K Participates in both transcription termination and antitermination
NPEIKGBL_03024 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NPEIKGBL_03025 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPEIKGBL_03026 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPEIKGBL_03027 7.7e-233 rasP M zinc metalloprotease
NPEIKGBL_03028 5e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NPEIKGBL_03029 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NPEIKGBL_03030 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPEIKGBL_03031 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPEIKGBL_03032 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NPEIKGBL_03033 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPEIKGBL_03034 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NPEIKGBL_03035 4.3e-78 ylxL
NPEIKGBL_03036 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEIKGBL_03037 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NPEIKGBL_03038 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NPEIKGBL_03039 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NPEIKGBL_03040 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NPEIKGBL_03041 2.2e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NPEIKGBL_03042 6.3e-157 flhG D Belongs to the ParA family
NPEIKGBL_03043 1.5e-200 flhF N Flagellar biosynthesis regulator FlhF
NPEIKGBL_03044 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NPEIKGBL_03045 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NPEIKGBL_03046 3.6e-132 fliR N Flagellar biosynthetic protein FliR
NPEIKGBL_03047 2.2e-36 fliQ N Role in flagellar biosynthesis
NPEIKGBL_03048 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NPEIKGBL_03049 2.1e-96 fliZ N Flagellar biosynthesis protein, FliO
NPEIKGBL_03050 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NPEIKGBL_03051 4.7e-173 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NPEIKGBL_03052 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NPEIKGBL_03053 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NPEIKGBL_03054 8.2e-140 flgG N Flagellar basal body rod
NPEIKGBL_03055 2.3e-72 flgD N Flagellar basal body rod modification protein
NPEIKGBL_03056 8.6e-220 fliK N Flagellar hook-length control protein
NPEIKGBL_03057 7.7e-37 ylxF S MgtE intracellular N domain
NPEIKGBL_03058 1.5e-69 fliJ N Flagellar biosynthesis chaperone
NPEIKGBL_03059 9.4e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NPEIKGBL_03060 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NPEIKGBL_03061 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NPEIKGBL_03062 2.4e-255 fliF N The M ring may be actively involved in energy transduction
NPEIKGBL_03063 4.3e-31 fliE N Flagellar hook-basal body
NPEIKGBL_03064 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
NPEIKGBL_03065 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NPEIKGBL_03066 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NPEIKGBL_03067 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NPEIKGBL_03068 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NPEIKGBL_03069 2.5e-169 xerC L tyrosine recombinase XerC
NPEIKGBL_03070 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NPEIKGBL_03071 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPEIKGBL_03072 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NPEIKGBL_03073 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NPEIKGBL_03074 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NPEIKGBL_03075 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NPEIKGBL_03076 8.5e-291 ylqG
NPEIKGBL_03077 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPEIKGBL_03078 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPEIKGBL_03079 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPEIKGBL_03080 2.1e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NPEIKGBL_03081 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPEIKGBL_03082 1.3e-61 ylqD S YlqD protein
NPEIKGBL_03083 1.2e-36 ylqC S Belongs to the UPF0109 family
NPEIKGBL_03084 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NPEIKGBL_03085 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPEIKGBL_03086 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPEIKGBL_03087 2.9e-87
NPEIKGBL_03088 4.4e-175 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPEIKGBL_03089 0.0 smc D Required for chromosome condensation and partitioning
NPEIKGBL_03090 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPEIKGBL_03091 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPEIKGBL_03092 6.1e-129 IQ reductase
NPEIKGBL_03093 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NPEIKGBL_03094 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPEIKGBL_03095 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NPEIKGBL_03096 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPEIKGBL_03097 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NPEIKGBL_03098 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NPEIKGBL_03099 1.6e-299 yloV S kinase related to dihydroxyacetone kinase
NPEIKGBL_03100 5.5e-59 asp S protein conserved in bacteria
NPEIKGBL_03101 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NPEIKGBL_03102 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NPEIKGBL_03103 9.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NPEIKGBL_03104 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPEIKGBL_03105 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NPEIKGBL_03106 1e-139 stp 3.1.3.16 T phosphatase
NPEIKGBL_03107 2e-205 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NPEIKGBL_03108 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPEIKGBL_03109 1.4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPEIKGBL_03110 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPEIKGBL_03111 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPEIKGBL_03112 8.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPEIKGBL_03113 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NPEIKGBL_03114 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NPEIKGBL_03115 1.5e-40 ylzA S Belongs to the UPF0296 family
NPEIKGBL_03116 6.9e-156 yloC S stress-induced protein
NPEIKGBL_03117 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NPEIKGBL_03118 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NPEIKGBL_03119 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NPEIKGBL_03120 1.1e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NPEIKGBL_03121 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NPEIKGBL_03122 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NPEIKGBL_03123 3.8e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NPEIKGBL_03124 7e-179 cysP P phosphate transporter
NPEIKGBL_03125 1.1e-140 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NPEIKGBL_03127 7.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPEIKGBL_03128 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPEIKGBL_03129 1.3e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPEIKGBL_03130 3.2e-141 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NPEIKGBL_03131 0.0 carB 6.3.5.5 F Belongs to the CarB family
NPEIKGBL_03132 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NPEIKGBL_03133 1.4e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPEIKGBL_03134 2.5e-164 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NPEIKGBL_03135 9.9e-231 pyrP F Xanthine uracil
NPEIKGBL_03136 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPEIKGBL_03137 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPEIKGBL_03138 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPEIKGBL_03139 3.8e-63 dksA T COG1734 DnaK suppressor protein
NPEIKGBL_03140 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPEIKGBL_03141 2.6e-67 divIVA D Cell division initiation protein
NPEIKGBL_03142 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NPEIKGBL_03143 1.3e-39 yggT S membrane
NPEIKGBL_03144 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NPEIKGBL_03145 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NPEIKGBL_03146 1.9e-155 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NPEIKGBL_03147 2.4e-37 ylmC S sporulation protein
NPEIKGBL_03148 1e-253 argE 3.5.1.16 E Acetylornithine deacetylase
NPEIKGBL_03149 6.9e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NPEIKGBL_03150 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEIKGBL_03151 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEIKGBL_03152 1.6e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NPEIKGBL_03154 0.0 bpr O COG1404 Subtilisin-like serine proteases
NPEIKGBL_03155 3.6e-42 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPEIKGBL_03156 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
NPEIKGBL_03157 0.0 fusAA Q Non-ribosomal peptide synthetase modules and related proteins
NPEIKGBL_03158 6.2e-173 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPEIKGBL_03159 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPEIKGBL_03160 6.2e-58 sbp S small basic protein
NPEIKGBL_03161 1.8e-91 ylxX S protein conserved in bacteria
NPEIKGBL_03162 2.4e-103 ylxW S protein conserved in bacteria
NPEIKGBL_03163 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPEIKGBL_03164 5.3e-167 murB 1.3.1.98 M cell wall formation
NPEIKGBL_03165 2.5e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPEIKGBL_03166 5.7e-186 spoVE D Belongs to the SEDS family
NPEIKGBL_03167 1.7e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPEIKGBL_03168 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPEIKGBL_03169 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPEIKGBL_03170 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NPEIKGBL_03171 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NPEIKGBL_03172 3.7e-44 ftsL D Essential cell division protein
NPEIKGBL_03173 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPEIKGBL_03174 2.9e-78 mraZ K Belongs to the MraZ family
NPEIKGBL_03175 3.3e-305 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NPEIKGBL_03176 4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPEIKGBL_03177 1.5e-88 ylbP K n-acetyltransferase
NPEIKGBL_03178 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NPEIKGBL_03179 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NPEIKGBL_03180 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
NPEIKGBL_03182 8.3e-123 ylbM S Belongs to the UPF0348 family
NPEIKGBL_03183 1.7e-13 yqgA
NPEIKGBL_03184 4.4e-186 ylbL T Belongs to the peptidase S16 family
NPEIKGBL_03185 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
NPEIKGBL_03186 1.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
NPEIKGBL_03187 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPEIKGBL_03188 6e-97 rsmD 2.1.1.171 L Methyltransferase
NPEIKGBL_03189 3.7e-38 ylbG S UPF0298 protein
NPEIKGBL_03190 1.8e-75 ylbF S Belongs to the UPF0342 family
NPEIKGBL_03191 6.7e-37 ylbE S YlbE-like protein
NPEIKGBL_03192 4.1e-63 ylbD S Putative coat protein
NPEIKGBL_03193 4.8e-199 ylbC S protein with SCP PR1 domains
NPEIKGBL_03194 2.6e-74 ylbB T COG0517 FOG CBS domain
NPEIKGBL_03195 7e-62 ylbA S YugN-like family
NPEIKGBL_03196 8.8e-167 ctaG S cytochrome c oxidase
NPEIKGBL_03197 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NPEIKGBL_03198 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NPEIKGBL_03199 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NPEIKGBL_03200 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NPEIKGBL_03201 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NPEIKGBL_03202 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NPEIKGBL_03203 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NPEIKGBL_03204 7.9e-211 ftsW D Belongs to the SEDS family
NPEIKGBL_03205 8.7e-44 ylaN S Belongs to the UPF0358 family
NPEIKGBL_03206 1e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
NPEIKGBL_03207 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NPEIKGBL_03208 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NPEIKGBL_03209 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPEIKGBL_03210 2.5e-32 ylaI S protein conserved in bacteria
NPEIKGBL_03211 4.2e-47 ylaH S YlaH-like protein
NPEIKGBL_03212 0.0 typA T GTP-binding protein TypA
NPEIKGBL_03213 8.2e-22 S Family of unknown function (DUF5325)
NPEIKGBL_03214 2.6e-37 ylaE
NPEIKGBL_03215 4.5e-11 sigC S Putative zinc-finger
NPEIKGBL_03216 1.1e-18 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NPEIKGBL_03217 3e-41 ylaB
NPEIKGBL_03218 0.0 ylaA
NPEIKGBL_03219 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NPEIKGBL_03220 1.5e-169 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NPEIKGBL_03221 2.6e-77 ykzC S Acetyltransferase (GNAT) family
NPEIKGBL_03222 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
NPEIKGBL_03223 7.1e-26 ykzI
NPEIKGBL_03224 2.1e-117 yktB S Belongs to the UPF0637 family
NPEIKGBL_03225 2e-42 yktA S Belongs to the UPF0223 family
NPEIKGBL_03226 3.5e-277 speA 4.1.1.19 E Arginine
NPEIKGBL_03227 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NPEIKGBL_03228 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NPEIKGBL_03229 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPEIKGBL_03230 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPEIKGBL_03231 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NPEIKGBL_03232 2e-115 recN L Putative cell-wall binding lipoprotein
NPEIKGBL_03234 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPEIKGBL_03235 5.5e-147 ykrA S hydrolases of the HAD superfamily
NPEIKGBL_03236 8.2e-31 ykzG S Belongs to the UPF0356 family
NPEIKGBL_03237 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPEIKGBL_03238 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NPEIKGBL_03239 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NPEIKGBL_03240 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NPEIKGBL_03241 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NPEIKGBL_03242 1.5e-43 abrB K of stationary sporulation gene expression
NPEIKGBL_03243 7.7e-183 mreB D Rod-share determining protein MreBH
NPEIKGBL_03244 1.1e-12 S Uncharacterized protein YkpC
NPEIKGBL_03245 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NPEIKGBL_03246 2.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPEIKGBL_03247 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPEIKGBL_03248 8.1e-39 ykoA
NPEIKGBL_03249 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NPEIKGBL_03250 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NPEIKGBL_03251 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NPEIKGBL_03252 3.1e-136 fruR K Transcriptional regulator
NPEIKGBL_03253 6.2e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NPEIKGBL_03254 2.5e-124 macB V ABC transporter, ATP-binding protein
NPEIKGBL_03255 1.2e-157 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NPEIKGBL_03256 1.5e-116 yknW S Yip1 domain
NPEIKGBL_03257 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NPEIKGBL_03258 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NPEIKGBL_03259 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NPEIKGBL_03260 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NPEIKGBL_03261 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NPEIKGBL_03262 2.4e-245 moeA 2.10.1.1 H molybdopterin
NPEIKGBL_03263 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NPEIKGBL_03264 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NPEIKGBL_03265 1.2e-145 yknT
NPEIKGBL_03266 5.8e-95 rok K Repressor of ComK
NPEIKGBL_03267 4.4e-82 ykuV CO thiol-disulfide
NPEIKGBL_03268 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NPEIKGBL_03269 8.8e-142 ykuT M Mechanosensitive ion channel
NPEIKGBL_03270 9e-37 ykuS S Belongs to the UPF0180 family
NPEIKGBL_03271 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NPEIKGBL_03272 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NPEIKGBL_03273 3.2e-80 fld C Flavodoxin
NPEIKGBL_03274 3.2e-177 ykuO
NPEIKGBL_03275 5.7e-88 fld C Flavodoxin domain
NPEIKGBL_03276 3.5e-168 ccpC K Transcriptional regulator
NPEIKGBL_03277 1.6e-76 ykuL S CBS domain
NPEIKGBL_03278 3.9e-27 ykzF S Antirepressor AbbA
NPEIKGBL_03279 4.4e-94 ykuK S Ribonuclease H-like
NPEIKGBL_03280 3.9e-37 ykuJ S protein conserved in bacteria
NPEIKGBL_03281 5.2e-234 ykuI T Diguanylate phosphodiesterase
NPEIKGBL_03283 0.0 3.2.1.132 M Putative peptidoglycan binding domain
NPEIKGBL_03284 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEIKGBL_03285 8e-165 ykuE S Metallophosphoesterase
NPEIKGBL_03286 4.6e-88 ykuD S protein conserved in bacteria
NPEIKGBL_03287 1.6e-238 ykuC EGP Major facilitator Superfamily
NPEIKGBL_03288 1.7e-84 ykyB S YkyB-like protein
NPEIKGBL_03289 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NPEIKGBL_03290 2.2e-15
NPEIKGBL_03291 8.8e-223 patA 2.6.1.1 E Aminotransferase
NPEIKGBL_03292 0.0 pilS 2.7.13.3 T Histidine kinase
NPEIKGBL_03293 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NPEIKGBL_03294 8e-124 ykwD J protein with SCP PR1 domains
NPEIKGBL_03295 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NPEIKGBL_03296 1.3e-263 mcpC NT chemotaxis protein
NPEIKGBL_03297 4.6e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEIKGBL_03298 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
NPEIKGBL_03299 7.2e-39 splA S Transcriptional regulator
NPEIKGBL_03300 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPEIKGBL_03301 2.1e-39 ptsH G phosphocarrier protein HPr
NPEIKGBL_03302 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPEIKGBL_03303 4.5e-128 glcT K antiterminator
NPEIKGBL_03305 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
NPEIKGBL_03307 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NPEIKGBL_03308 3.8e-09
NPEIKGBL_03309 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NPEIKGBL_03310 4.9e-90 stoA CO thiol-disulfide
NPEIKGBL_03311 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPEIKGBL_03312 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
NPEIKGBL_03313 2.8e-28
NPEIKGBL_03314 6e-25 ykvS S protein conserved in bacteria
NPEIKGBL_03315 5.6e-46 ykvR S Protein of unknown function (DUF3219)
NPEIKGBL_03316 8.5e-133 G Glycosyl hydrolases family 18
NPEIKGBL_03317 1.2e-35 3.5.1.104 M LysM domain
NPEIKGBL_03318 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
NPEIKGBL_03319 5.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
NPEIKGBL_03320 3.8e-60 ykvN K HxlR-like helix-turn-helix
NPEIKGBL_03321 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NPEIKGBL_03322 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NPEIKGBL_03323 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NPEIKGBL_03324 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NPEIKGBL_03325 8.7e-182 ykvI S membrane
NPEIKGBL_03326 0.0 clpE O Belongs to the ClpA ClpB family
NPEIKGBL_03327 1e-137 motA N flagellar motor
NPEIKGBL_03328 2.5e-125 motB N Flagellar motor protein
NPEIKGBL_03329 1.3e-75 ykvE K transcriptional
NPEIKGBL_03330 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NPEIKGBL_03331 1.8e-64 eag
NPEIKGBL_03332 6.4e-09 S Spo0E like sporulation regulatory protein
NPEIKGBL_03333 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
NPEIKGBL_03334 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NPEIKGBL_03335 4.7e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NPEIKGBL_03336 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NPEIKGBL_03337 1.3e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NPEIKGBL_03338 3.4e-230 mtnE 2.6.1.83 E Aminotransferase
NPEIKGBL_03339 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NPEIKGBL_03340 5.4e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NPEIKGBL_03341 4.8e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NPEIKGBL_03343 2e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NPEIKGBL_03344 0.0 kinE 2.7.13.3 T Histidine kinase
NPEIKGBL_03345 7.2e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NPEIKGBL_03346 1.4e-18 ykzE
NPEIKGBL_03347 1.2e-10 ydfR S Protein of unknown function (DUF421)
NPEIKGBL_03348 1.1e-232 ktrB P COG0168 Trk-type K transport systems, membrane components
NPEIKGBL_03349 3.5e-155 htpX O Belongs to the peptidase M48B family
NPEIKGBL_03350 7.3e-124 ykrK S Domain of unknown function (DUF1836)
NPEIKGBL_03351 1.9e-26 sspD S small acid-soluble spore protein
NPEIKGBL_03352 4.5e-115 rsgI S Anti-sigma factor N-terminus
NPEIKGBL_03353 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPEIKGBL_03354 1.3e-176 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NPEIKGBL_03355 3.5e-109 ykoX S membrane-associated protein
NPEIKGBL_03356 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
NPEIKGBL_03357 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NPEIKGBL_03358 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NPEIKGBL_03359 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NPEIKGBL_03360 0.0 ykoS
NPEIKGBL_03361 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NPEIKGBL_03362 3.7e-99 ykoP G polysaccharide deacetylase
NPEIKGBL_03363 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NPEIKGBL_03364 1.3e-81 mhqR K transcriptional
NPEIKGBL_03365 6.9e-26 ykoL
NPEIKGBL_03366 5.9e-18
NPEIKGBL_03367 1.4e-53 tnrA K transcriptional
NPEIKGBL_03368 2.2e-222 mgtE P Acts as a magnesium transporter
NPEIKGBL_03371 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
NPEIKGBL_03372 5.8e-110 ykoI S Peptidase propeptide and YPEB domain
NPEIKGBL_03373 2.6e-242 ykoH 2.7.13.3 T Histidine kinase
NPEIKGBL_03374 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPEIKGBL_03375 1.1e-109 ykoF S YKOF-related Family
NPEIKGBL_03376 2.6e-98 ykoE S ABC-type cobalt transport system, permease component
NPEIKGBL_03377 4.7e-307 P ABC transporter, ATP-binding protein
NPEIKGBL_03378 4.5e-135 ykoC P Cobalt transport protein
NPEIKGBL_03379 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPEIKGBL_03380 1.7e-176 isp O Belongs to the peptidase S8 family
NPEIKGBL_03381 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NPEIKGBL_03382 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NPEIKGBL_03383 8.4e-72 ohrB O Organic hydroperoxide resistance protein
NPEIKGBL_03384 3.9e-75 ohrR K COG1846 Transcriptional regulators
NPEIKGBL_03385 4.8e-70 ohrA O Organic hydroperoxide resistance protein
NPEIKGBL_03386 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NPEIKGBL_03387 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPEIKGBL_03388 8.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NPEIKGBL_03389 7e-50 ykkD P Multidrug resistance protein
NPEIKGBL_03390 3.5e-55 ykkC P Multidrug resistance protein
NPEIKGBL_03391 1.7e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NPEIKGBL_03392 8.8e-98 ykkA S Protein of unknown function (DUF664)
NPEIKGBL_03393 2.7e-129 ykjA S Protein of unknown function (DUF421)
NPEIKGBL_03394 7.2e-09
NPEIKGBL_03395 5.1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NPEIKGBL_03396 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NPEIKGBL_03397 2e-160 ykgA E Amidinotransferase
NPEIKGBL_03398 3.6e-204 pgl 3.1.1.31 G 6-phosphogluconolactonase
NPEIKGBL_03399 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
NPEIKGBL_03400 8.5e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NPEIKGBL_03401 6.1e-202 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NPEIKGBL_03402 4.5e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NPEIKGBL_03404 0.0 dppE E ABC transporter substrate-binding protein
NPEIKGBL_03405 5.1e-187 dppD P Belongs to the ABC transporter superfamily
NPEIKGBL_03406 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEIKGBL_03407 5.3e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEIKGBL_03408 1.9e-152 dppA E D-aminopeptidase
NPEIKGBL_03409 3.4e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NPEIKGBL_03410 8.4e-209 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPEIKGBL_03412 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NPEIKGBL_03413 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPEIKGBL_03414 2.7e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NPEIKGBL_03415 1.2e-239 steT E amino acid
NPEIKGBL_03416 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NPEIKGBL_03417 7.6e-175 pit P phosphate transporter
NPEIKGBL_03418 1.5e-135 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NPEIKGBL_03419 6.7e-23 spoIISB S Stage II sporulation protein SB
NPEIKGBL_03420 2e-64 G Acyltransferase family
NPEIKGBL_03421 3.9e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NPEIKGBL_03422 1.8e-38 xhlB S SPP1 phage holin
NPEIKGBL_03423 6.2e-39 xhlA S Haemolysin XhlA
NPEIKGBL_03424 1.3e-151 xepA
NPEIKGBL_03425 3.8e-23 xkdX
NPEIKGBL_03426 5.4e-53 xkdW S XkdW protein
NPEIKGBL_03427 4.6e-190
NPEIKGBL_03428 6.7e-41
NPEIKGBL_03429 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NPEIKGBL_03430 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NPEIKGBL_03431 9.6e-71 xkdS S Protein of unknown function (DUF2634)
NPEIKGBL_03432 2.1e-39 xkdR S Protein of unknown function (DUF2577)
NPEIKGBL_03433 1.8e-181 yqbQ 3.2.1.96 G NLP P60 protein
NPEIKGBL_03434 4.6e-120 xkdP S Lysin motif
NPEIKGBL_03435 0.0 xkdO L Transglycosylase SLT domain
NPEIKGBL_03436 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
NPEIKGBL_03437 6.1e-76 xkdM S Phage tail tube protein
NPEIKGBL_03438 2.5e-256 xkdK S Phage tail sheath C-terminal domain
NPEIKGBL_03439 4.3e-74 xkdJ
NPEIKGBL_03440 4.9e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
NPEIKGBL_03441 3.6e-63 yqbH S Domain of unknown function (DUF3599)
NPEIKGBL_03442 4.3e-62 yqbG S Protein of unknown function (DUF3199)
NPEIKGBL_03443 5.8e-169 xkdG S Phage capsid family
NPEIKGBL_03444 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NPEIKGBL_03445 5.1e-284 yqbA S portal protein
NPEIKGBL_03446 5.3e-253 xtmB S phage terminase, large subunit
NPEIKGBL_03447 2.6e-138 xtmA L phage terminase small subunit
NPEIKGBL_03448 3.7e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NPEIKGBL_03449 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
NPEIKGBL_03453 2.7e-117 xkdC L Bacterial dnaA protein
NPEIKGBL_03454 1.5e-155 xkdB K sequence-specific DNA binding
NPEIKGBL_03456 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
NPEIKGBL_03457 2.3e-110 xkdA E IrrE N-terminal-like domain
NPEIKGBL_03458 2.8e-159 ydbD P Catalase
NPEIKGBL_03459 2.1e-111 yjqB S Pfam:DUF867
NPEIKGBL_03460 6.1e-61 yjqA S Bacterial PH domain
NPEIKGBL_03461 1.9e-167 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NPEIKGBL_03462 3.1e-40 S YCII-related domain
NPEIKGBL_03464 1e-212 S response regulator aspartate phosphatase
NPEIKGBL_03465 8e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NPEIKGBL_03466 2.3e-78 yjoA S DinB family
NPEIKGBL_03467 4.3e-130 MA20_18170 S membrane transporter protein
NPEIKGBL_03468 4.3e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NPEIKGBL_03469 1.4e-283 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NPEIKGBL_03470 1.5e-183 exuR K transcriptional
NPEIKGBL_03471 1.1e-226 exuT G Sugar (and other) transporter
NPEIKGBL_03472 6.8e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPEIKGBL_03473 3.4e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NPEIKGBL_03474 2.6e-191 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NPEIKGBL_03475 2.7e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NPEIKGBL_03476 1.4e-248 yjmB G symporter YjmB
NPEIKGBL_03477 3.5e-279 uxaC 5.3.1.12 G glucuronate isomerase
NPEIKGBL_03478 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
NPEIKGBL_03479 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NPEIKGBL_03480 2e-91 yjlB S Cupin domain
NPEIKGBL_03481 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
NPEIKGBL_03482 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NPEIKGBL_03483 1.9e-122 ybbM S transport system, permease component
NPEIKGBL_03484 4.6e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NPEIKGBL_03485 1.4e-29
NPEIKGBL_03486 1.3e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NPEIKGBL_03487 1.2e-222 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NPEIKGBL_03489 2.4e-115 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NPEIKGBL_03490 8.7e-07 S Domain of unknown function (DUF4352)
NPEIKGBL_03491 4.3e-95 yjgD S Protein of unknown function (DUF1641)
NPEIKGBL_03492 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NPEIKGBL_03493 2e-103 yjgB S Domain of unknown function (DUF4309)
NPEIKGBL_03494 4.6e-45 T PhoQ Sensor
NPEIKGBL_03495 1.6e-163 yjfC O Predicted Zn-dependent protease (DUF2268)
NPEIKGBL_03496 2.3e-20 yjfB S Putative motility protein
NPEIKGBL_03497 3e-81 S Protein of unknown function (DUF2690)
NPEIKGBL_03498 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
NPEIKGBL_03500 7.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NPEIKGBL_03501 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
NPEIKGBL_03502 4.2e-29 S Domain of unknown function (DUF4177)
NPEIKGBL_03503 6.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NPEIKGBL_03505 1e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NPEIKGBL_03506 4.1e-50 yjdF S Protein of unknown function (DUF2992)
NPEIKGBL_03507 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NPEIKGBL_03508 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NPEIKGBL_03509 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NPEIKGBL_03511 9.2e-141 IQ Enoyl-(Acyl carrier protein) reductase
NPEIKGBL_03512 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
NPEIKGBL_03513 2.8e-36 yqaS L DNA packaging
NPEIKGBL_03514 4.4e-44 yjcN
NPEIKGBL_03515 4.6e-190 S Putative amidase domain
NPEIKGBL_03519 5.4e-212 yjcL S Protein of unknown function (DUF819)
NPEIKGBL_03520 2.9e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
NPEIKGBL_03521 4.2e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NPEIKGBL_03522 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NPEIKGBL_03523 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
NPEIKGBL_03524 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NPEIKGBL_03525 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEIKGBL_03526 4.9e-38
NPEIKGBL_03527 0.0 yjcD 3.6.4.12 L DNA helicase
NPEIKGBL_03528 2.9e-38 spoVIF S Stage VI sporulation protein F
NPEIKGBL_03531 9.6e-56 yjcA S Protein of unknown function (DUF1360)
NPEIKGBL_03532 5.3e-52 cotV S Spore Coat Protein X and V domain
NPEIKGBL_03533 5.5e-26 cotW
NPEIKGBL_03534 3.6e-72 cotX S Spore Coat Protein X and V domain
NPEIKGBL_03535 3.4e-96 cotY S Spore coat protein Z
NPEIKGBL_03536 8.9e-83 cotZ S Spore coat protein
NPEIKGBL_03537 1.7e-53 yjbX S Spore coat protein
NPEIKGBL_03538 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NPEIKGBL_03539 5.8e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NPEIKGBL_03540 2.5e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NPEIKGBL_03541 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NPEIKGBL_03542 6.7e-30 thiS H thiamine diphosphate biosynthetic process
NPEIKGBL_03543 1.7e-215 thiO 1.4.3.19 E Glycine oxidase
NPEIKGBL_03544 1.4e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NPEIKGBL_03545 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NPEIKGBL_03546 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NPEIKGBL_03547 3.3e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NPEIKGBL_03548 2.2e-157 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPEIKGBL_03549 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPEIKGBL_03550 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NPEIKGBL_03551 7.8e-61 yjbL S Belongs to the UPF0738 family
NPEIKGBL_03552 1e-99 yjbK S protein conserved in bacteria
NPEIKGBL_03553 1.3e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NPEIKGBL_03554 1.4e-71 yjbI S Bacterial-like globin
NPEIKGBL_03555 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NPEIKGBL_03557 1.8e-20
NPEIKGBL_03558 0.0 pepF E oligoendopeptidase F
NPEIKGBL_03559 9.5e-222 yjbF S Competence protein
NPEIKGBL_03560 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NPEIKGBL_03561 6e-112 yjbE P Integral membrane protein TerC family
NPEIKGBL_03562 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPEIKGBL_03563 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEIKGBL_03564 9.1e-204 yjbB EGP Major Facilitator Superfamily
NPEIKGBL_03565 5.5e-172 oppF E Belongs to the ABC transporter superfamily
NPEIKGBL_03566 6.8e-198 oppD P Belongs to the ABC transporter superfamily
NPEIKGBL_03567 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEIKGBL_03568 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEIKGBL_03569 0.0 oppA E ABC transporter substrate-binding protein
NPEIKGBL_03570 6.8e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NPEIKGBL_03571 5e-147 yjbA S Belongs to the UPF0736 family
NPEIKGBL_03572 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEIKGBL_03573 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPEIKGBL_03574 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NPEIKGBL_03575 3.6e-185 appF E Belongs to the ABC transporter superfamily
NPEIKGBL_03576 3.3e-183 appD P Belongs to the ABC transporter superfamily
NPEIKGBL_03577 3.9e-150 yjaZ O Zn-dependent protease
NPEIKGBL_03578 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPEIKGBL_03579 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPEIKGBL_03580 2.7e-22 yjzB
NPEIKGBL_03581 7.3e-26 comZ S ComZ
NPEIKGBL_03582 2.5e-183 med S Transcriptional activator protein med
NPEIKGBL_03583 6.9e-101 yjaV
NPEIKGBL_03584 3.1e-141 yjaU I carboxylic ester hydrolase activity
NPEIKGBL_03585 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NPEIKGBL_03586 9.5e-28 yjzC S YjzC-like protein
NPEIKGBL_03587 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NPEIKGBL_03588 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NPEIKGBL_03589 3.3e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NPEIKGBL_03590 4.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NPEIKGBL_03591 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NPEIKGBL_03592 3.4e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NPEIKGBL_03593 1.1e-195 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NPEIKGBL_03594 1.7e-88 norB G Major Facilitator Superfamily
NPEIKGBL_03595 9.2e-267 yitY C D-arabinono-1,4-lactone oxidase
NPEIKGBL_03596 1.5e-22 pilT S Proteolipid membrane potential modulator
NPEIKGBL_03597 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NPEIKGBL_03598 5.5e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NPEIKGBL_03599 4.6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NPEIKGBL_03601 1.2e-17 S Protein of unknown function (DUF3813)
NPEIKGBL_03602 5e-73 ipi S Intracellular proteinase inhibitor
NPEIKGBL_03603 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NPEIKGBL_03604 8.4e-159 yitS S protein conserved in bacteria
NPEIKGBL_03605 1.3e-309 nprB 3.4.24.28 E Peptidase M4
NPEIKGBL_03606 9.1e-44 yitR S Domain of unknown function (DUF3784)
NPEIKGBL_03607 6.6e-94
NPEIKGBL_03608 4.5e-58 K Transcriptional regulator PadR-like family
NPEIKGBL_03609 1.5e-97 S Sporulation delaying protein SdpA
NPEIKGBL_03610 1.4e-170
NPEIKGBL_03611 8.5e-94
NPEIKGBL_03612 2.6e-160 cvfB S protein conserved in bacteria
NPEIKGBL_03613 8.6e-55 yajQ S Belongs to the UPF0234 family
NPEIKGBL_03614 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NPEIKGBL_03615 1.2e-71 yjcF S Acetyltransferase (GNAT) domain
NPEIKGBL_03616 4.8e-154 yitH K Acetyltransferase (GNAT) domain
NPEIKGBL_03617 5.7e-228 yitG EGP Major facilitator Superfamily
NPEIKGBL_03618 9.2e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NPEIKGBL_03619 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPEIKGBL_03620 7.1e-141 yitD 4.4.1.19 S synthase
NPEIKGBL_03621 3.3e-121 comB 3.1.3.71 H Belongs to the ComB family
NPEIKGBL_03622 1e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NPEIKGBL_03623 2.7e-232 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NPEIKGBL_03624 1.4e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NPEIKGBL_03625 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NPEIKGBL_03626 2.2e-34 mcbG S Pentapeptide repeats (9 copies)
NPEIKGBL_03627 2.2e-276 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPEIKGBL_03628 7.8e-106 argO S Lysine exporter protein LysE YggA
NPEIKGBL_03629 8.2e-93 yisT S DinB family
NPEIKGBL_03630 5.4e-192 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NPEIKGBL_03631 6.9e-184 purR K helix_turn _helix lactose operon repressor
NPEIKGBL_03632 1.2e-160 yisR K Transcriptional regulator
NPEIKGBL_03633 4e-243 yisQ V Mate efflux family protein
NPEIKGBL_03634 1.7e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NPEIKGBL_03635 4.7e-88 yizA S Damage-inducible protein DinB
NPEIKGBL_03636 0.0 asnO 6.3.5.4 E Asparagine synthase
NPEIKGBL_03637 2.2e-99 yisN S Protein of unknown function (DUF2777)
NPEIKGBL_03638 0.0 wprA O Belongs to the peptidase S8 family
NPEIKGBL_03639 3e-57 yisL S UPF0344 protein
NPEIKGBL_03640 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NPEIKGBL_03641 1.1e-172 cotH M Spore Coat
NPEIKGBL_03642 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NPEIKGBL_03643 1.9e-33 gerPA S Spore germination protein
NPEIKGBL_03644 4e-34 gerPB S cell differentiation
NPEIKGBL_03645 1.8e-54 gerPC S Spore germination protein
NPEIKGBL_03646 6.3e-24 gerPD S Spore germination protein
NPEIKGBL_03647 3e-66 gerPE S Spore germination protein GerPE
NPEIKGBL_03648 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NPEIKGBL_03649 3e-50 yisB V COG1403 Restriction endonuclease
NPEIKGBL_03650 0.0 sbcC L COG0419 ATPase involved in DNA repair
NPEIKGBL_03651 2.8e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NPEIKGBL_03652 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NPEIKGBL_03653 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NPEIKGBL_03654 2.2e-78 yhjR S Rubrerythrin
NPEIKGBL_03655 6.5e-35 yhjQ C COG1145 Ferredoxin
NPEIKGBL_03656 0.0 S Sugar transport-related sRNA regulator N-term
NPEIKGBL_03657 9.9e-214 EGP Transmembrane secretion effector
NPEIKGBL_03658 1.9e-201 abrB S membrane
NPEIKGBL_03659 3.8e-187 yhjM 5.1.1.1 K Transcriptional regulator
NPEIKGBL_03660 4.5e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NPEIKGBL_03661 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NPEIKGBL_03662 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NPEIKGBL_03663 5.8e-214 glcP G Major Facilitator Superfamily
NPEIKGBL_03664 1.5e-92 yhjH K helix_turn_helix multiple antibiotic resistance protein
NPEIKGBL_03665 1.1e-281 yhjG CH FAD binding domain
NPEIKGBL_03666 7.6e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NPEIKGBL_03667 9.1e-110 yhjE S SNARE associated Golgi protein
NPEIKGBL_03668 2.5e-59 yhjD
NPEIKGBL_03669 4.5e-26 yhjC S Protein of unknown function (DUF3311)
NPEIKGBL_03670 3.4e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPEIKGBL_03671 9.5e-40 yhjA S Excalibur calcium-binding domain
NPEIKGBL_03672 5.2e-167 IQ Enoyl-(Acyl carrier protein) reductase
NPEIKGBL_03673 4.2e-109 comK K Competence transcription factor
NPEIKGBL_03674 1.3e-32 yhzC S IDEAL
NPEIKGBL_03675 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEIKGBL_03676 5.2e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NPEIKGBL_03677 1.1e-181 hemAT NT chemotaxis protein
NPEIKGBL_03678 1.9e-90 bioY S BioY family
NPEIKGBL_03679 9.9e-277 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NPEIKGBL_03680 6.5e-196 vraB 2.3.1.9 I Belongs to the thiolase family
NPEIKGBL_03681 1.2e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NPEIKGBL_03682 2.2e-155 yfmC M Periplasmic binding protein
NPEIKGBL_03683 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
NPEIKGBL_03684 4.3e-77 VY92_01935 K acetyltransferase
NPEIKGBL_03685 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NPEIKGBL_03686 1.2e-241 yhfN 3.4.24.84 O Peptidase M48
NPEIKGBL_03687 1.9e-65 yhfM
NPEIKGBL_03688 2.7e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NPEIKGBL_03689 5.5e-110 yhfK GM NmrA-like family
NPEIKGBL_03690 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
NPEIKGBL_03691 1.2e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NPEIKGBL_03692 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPEIKGBL_03693 3.7e-72 3.4.13.21 S ASCH
NPEIKGBL_03694 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NPEIKGBL_03695 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
NPEIKGBL_03696 1.1e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPEIKGBL_03697 1e-238 yhgE S YhgE Pip N-terminal domain protein
NPEIKGBL_03698 5.4e-101 yhgD K Transcriptional regulator
NPEIKGBL_03699 3.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NPEIKGBL_03700 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NPEIKGBL_03701 1.2e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NPEIKGBL_03702 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NPEIKGBL_03703 6.4e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NPEIKGBL_03704 7.5e-17 1.15.1.2 C Rubrerythrin
NPEIKGBL_03705 2.8e-244 yhfA C membrane
NPEIKGBL_03706 2.4e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NPEIKGBL_03707 4.5e-113 ecsC S EcsC protein family
NPEIKGBL_03708 1.6e-214 ecsB U ABC transporter
NPEIKGBL_03709 8.8e-136 ecsA V transporter (ATP-binding protein)
NPEIKGBL_03710 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NPEIKGBL_03711 2.4e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NPEIKGBL_03712 3.6e-80 trpP S Tryptophan transporter TrpP
NPEIKGBL_03713 7e-39 yhaH S YtxH-like protein
NPEIKGBL_03714 1e-113 hpr K Negative regulator of protease production and sporulation
NPEIKGBL_03715 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NPEIKGBL_03716 1.9e-89 yhaK S Putative zincin peptidase
NPEIKGBL_03717 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPEIKGBL_03718 1.6e-21 yhaL S Sporulation protein YhaL
NPEIKGBL_03719 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NPEIKGBL_03720 0.0 yhaN L AAA domain
NPEIKGBL_03721 1.2e-222 yhaO L DNA repair exonuclease
NPEIKGBL_03722 2.7e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NPEIKGBL_03723 5.7e-166 yhaQ S ABC transporter, ATP-binding protein
NPEIKGBL_03724 1.1e-26 S YhzD-like protein
NPEIKGBL_03725 4.9e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
NPEIKGBL_03727 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NPEIKGBL_03728 2.8e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NPEIKGBL_03729 1.8e-292 hemZ H coproporphyrinogen III oxidase
NPEIKGBL_03730 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NPEIKGBL_03731 1.7e-204 yhaZ L DNA alkylation repair enzyme
NPEIKGBL_03732 9.5e-48 yheA S Belongs to the UPF0342 family
NPEIKGBL_03733 3.1e-201 yheB S Belongs to the UPF0754 family
NPEIKGBL_03734 4.3e-216 yheC HJ YheC/D like ATP-grasp
NPEIKGBL_03735 4.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NPEIKGBL_03736 3.8e-36 yheE S Family of unknown function (DUF5342)
NPEIKGBL_03737 6.3e-28 sspB S spore protein
NPEIKGBL_03738 1.5e-109 yheG GM NAD(P)H-binding
NPEIKGBL_03739 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NPEIKGBL_03740 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NPEIKGBL_03741 1.5e-83 nhaX T Belongs to the universal stress protein A family
NPEIKGBL_03742 1.7e-225 nhaC C Na H antiporter
NPEIKGBL_03743 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NPEIKGBL_03744 2.3e-148 yheN G deacetylase
NPEIKGBL_03745 2.5e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NPEIKGBL_03746 5.6e-203 yhdY M Mechanosensitive ion channel
NPEIKGBL_03748 1.8e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NPEIKGBL_03749 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPEIKGBL_03750 1.2e-42 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPEIKGBL_03751 2.5e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NPEIKGBL_03752 8.8e-223 yhdR 2.6.1.1 E Aminotransferase
NPEIKGBL_03753 3.2e-74 cueR K transcriptional
NPEIKGBL_03754 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NPEIKGBL_03755 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NPEIKGBL_03756 1.5e-191 yhdN C Aldo keto reductase
NPEIKGBL_03757 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NPEIKGBL_03758 7.3e-200 yhdL S Sigma factor regulator N-terminal
NPEIKGBL_03759 8.1e-45 yhdK S Sigma-M inhibitor protein
NPEIKGBL_03760 1.7e-75 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPEIKGBL_03761 1.8e-267 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPEIKGBL_03762 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NPEIKGBL_03763 3.4e-250 yhdG E amino acid
NPEIKGBL_03764 3e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEIKGBL_03765 5.9e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
NPEIKGBL_03766 3.8e-162 citR K Transcriptional regulator
NPEIKGBL_03767 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NPEIKGBL_03768 6.6e-254 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NPEIKGBL_03769 6.3e-276 ycgB S Stage V sporulation protein R
NPEIKGBL_03770 3.3e-238 ygxB M Conserved TM helix
NPEIKGBL_03771 1e-75 nsrR K Transcriptional regulator
NPEIKGBL_03772 1.8e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NPEIKGBL_03773 1.8e-53 yhdC S Protein of unknown function (DUF3889)
NPEIKGBL_03774 1.2e-38 yhdB S YhdB-like protein
NPEIKGBL_03775 3.6e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
NPEIKGBL_03776 1.7e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPEIKGBL_03777 3e-212 yhcY 2.7.13.3 T Histidine kinase
NPEIKGBL_03778 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NPEIKGBL_03779 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NPEIKGBL_03780 1.3e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPEIKGBL_03781 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NPEIKGBL_03782 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NPEIKGBL_03783 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPEIKGBL_03784 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NPEIKGBL_03785 1.3e-119 yhcW 5.4.2.6 S hydrolase
NPEIKGBL_03786 9.9e-68 yhcV S COG0517 FOG CBS domain
NPEIKGBL_03787 9.3e-68 yhcU S Family of unknown function (DUF5365)
NPEIKGBL_03788 1.5e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPEIKGBL_03789 2.3e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NPEIKGBL_03790 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NPEIKGBL_03791 5.2e-100 yhcQ M Spore coat protein
NPEIKGBL_03792 2.1e-166 yhcP
NPEIKGBL_03793 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPEIKGBL_03794 2.9e-41 yhcM
NPEIKGBL_03795 2.6e-218 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPEIKGBL_03796 1.3e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NPEIKGBL_03797 1.1e-150 metQ M Belongs to the nlpA lipoprotein family
NPEIKGBL_03798 1e-30 cspB K Cold-shock protein
NPEIKGBL_03799 2.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NPEIKGBL_03800 7.7e-166 yhcH V ABC transporter, ATP-binding protein
NPEIKGBL_03801 4e-122 yhcG V ABC transporter, ATP-binding protein
NPEIKGBL_03802 1.9e-59 yhcF K Transcriptional regulator
NPEIKGBL_03803 3.5e-55
NPEIKGBL_03804 5.2e-36 yhcC
NPEIKGBL_03805 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NPEIKGBL_03806 3.1e-271 yhcA EGP Major facilitator Superfamily
NPEIKGBL_03807 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NPEIKGBL_03808 2.2e-76 yhbI K DNA-binding transcription factor activity
NPEIKGBL_03809 1.6e-224 yhbH S Belongs to the UPF0229 family
NPEIKGBL_03810 0.0 prkA T Ser protein kinase
NPEIKGBL_03811 9.4e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NPEIKGBL_03812 7.8e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NPEIKGBL_03813 2.1e-109 yhbD K Protein of unknown function (DUF4004)
NPEIKGBL_03814 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPEIKGBL_03815 2.2e-173 yhbB S Putative amidase domain
NPEIKGBL_03816 3.9e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NPEIKGBL_03817 7.9e-114 yhzB S B3/4 domain
NPEIKGBL_03819 4.4e-29 K Transcriptional regulator
NPEIKGBL_03820 4.1e-78 ygaO
NPEIKGBL_03821 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPEIKGBL_03823 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NPEIKGBL_03824 4.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NPEIKGBL_03825 7.3e-170 ssuA M Sulfonate ABC transporter
NPEIKGBL_03826 1.3e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NPEIKGBL_03827 1.7e-289 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NPEIKGBL_03829 1.7e-262 ygaK C Berberine and berberine like
NPEIKGBL_03830 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NPEIKGBL_03831 7.2e-132 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NPEIKGBL_03832 1.2e-26
NPEIKGBL_03833 1.7e-142 spo0M S COG4326 Sporulation control protein
NPEIKGBL_03837 2e-08
NPEIKGBL_03845 7.8e-08
NPEIKGBL_03850 3.4e-39 S COG NOG14552 non supervised orthologous group
NPEIKGBL_03851 6.7e-167 ygxA S Nucleotidyltransferase-like
NPEIKGBL_03852 2.1e-55 ygzB S UPF0295 protein
NPEIKGBL_03853 4e-80 perR P Belongs to the Fur family
NPEIKGBL_03854 6.3e-87 bcp 1.11.1.15 O Peroxiredoxin
NPEIKGBL_03855 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NPEIKGBL_03856 8.7e-180 ygaE S Membrane
NPEIKGBL_03857 1.8e-301 ygaD V ABC transporter
NPEIKGBL_03858 1.3e-104 ygaC J Belongs to the UPF0374 family
NPEIKGBL_03859 1.5e-37 ygaB S YgaB-like protein
NPEIKGBL_03860 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NPEIKGBL_03861 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPEIKGBL_03862 6.9e-36 yfhS
NPEIKGBL_03863 1.2e-210 mutY L A G-specific
NPEIKGBL_03864 5.5e-186 yfhP S membrane-bound metal-dependent
NPEIKGBL_03865 0.0 yfhO S Bacterial membrane protein YfhO
NPEIKGBL_03866 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NPEIKGBL_03867 1.3e-170 yfhM S Alpha beta hydrolase
NPEIKGBL_03868 3e-47 yfhL S SdpI/YhfL protein family
NPEIKGBL_03869 1.3e-90 batE T Bacterial SH3 domain homologues
NPEIKGBL_03870 1.3e-44 yfhJ S WVELL protein
NPEIKGBL_03871 6.2e-20 sspK S reproduction
NPEIKGBL_03872 1.1e-209 yfhI EGP Major facilitator Superfamily
NPEIKGBL_03874 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NPEIKGBL_03875 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NPEIKGBL_03876 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
NPEIKGBL_03878 2.1e-25 yfhD S YfhD-like protein
NPEIKGBL_03879 3.9e-107 yfhC C nitroreductase
NPEIKGBL_03880 1.8e-167 yfhB 5.3.3.17 S PhzF family
NPEIKGBL_03881 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEIKGBL_03882 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEIKGBL_03883 6e-177 yfiY P ABC transporter substrate-binding protein
NPEIKGBL_03884 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPEIKGBL_03885 5.8e-80 yfiV K transcriptional
NPEIKGBL_03886 5.3e-284 yfiU EGP Major facilitator Superfamily
NPEIKGBL_03887 2.4e-98 yfiT S Belongs to the metal hydrolase YfiT family
NPEIKGBL_03888 2.6e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NPEIKGBL_03889 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NPEIKGBL_03890 8.3e-99 padR K transcriptional
NPEIKGBL_03891 6.9e-204 V COG0842 ABC-type multidrug transport system, permease component
NPEIKGBL_03892 2.8e-208 V ABC-2 family transporter protein
NPEIKGBL_03893 3.2e-167 V ABC transporter, ATP-binding protein
NPEIKGBL_03894 4.6e-112 KT LuxR family transcriptional regulator
NPEIKGBL_03895 4.4e-211 yxjM T Histidine kinase
NPEIKGBL_03897 3.7e-162 yfiE 1.13.11.2 S glyoxalase
NPEIKGBL_03898 6.4e-64 mhqP S DoxX
NPEIKGBL_03899 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NPEIKGBL_03900 6.8e-309 yfiB3 V ABC transporter
NPEIKGBL_03901 1e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPEIKGBL_03902 1.6e-140 glvR K Helix-turn-helix domain, rpiR family
NPEIKGBL_03903 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NPEIKGBL_03904 2.8e-43 yfjA S Belongs to the WXG100 family
NPEIKGBL_03905 9.2e-191 yfjB
NPEIKGBL_03906 4.1e-144 yfjC
NPEIKGBL_03907 6.9e-101 yfjD S Family of unknown function (DUF5381)
NPEIKGBL_03908 3.2e-79 S Family of unknown function (DUF5381)
NPEIKGBL_03909 4e-56 yfjF S UPF0060 membrane protein
NPEIKGBL_03910 9.8e-25 sspH S Belongs to the SspH family
NPEIKGBL_03911 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NPEIKGBL_03912 6.6e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NPEIKGBL_03913 2.1e-195 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPEIKGBL_03914 2.8e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPEIKGBL_03915 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NPEIKGBL_03917 4.6e-17 yfjL
NPEIKGBL_03918 1.1e-83 yfjM S Psort location Cytoplasmic, score
NPEIKGBL_03919 6.2e-190 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPEIKGBL_03920 3.9e-44 S YfzA-like protein
NPEIKGBL_03921 9e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPEIKGBL_03922 5.5e-166 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NPEIKGBL_03923 1.7e-184 corA P Mediates influx of magnesium ions
NPEIKGBL_03924 1.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NPEIKGBL_03925 1.7e-153 pdaA G deacetylase
NPEIKGBL_03926 1.1e-26 yfjT
NPEIKGBL_03927 5.4e-222 yfkA S YfkB-like domain
NPEIKGBL_03928 3e-148 yfkC M Mechanosensitive ion channel
NPEIKGBL_03929 1.2e-146 yfkD S YfkD-like protein
NPEIKGBL_03930 6.1e-183 cax P COG0387 Ca2 H antiporter
NPEIKGBL_03931 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NPEIKGBL_03932 9.7e-144 yihY S Belongs to the UPF0761 family
NPEIKGBL_03933 2.4e-50 yfkI S gas vesicle protein
NPEIKGBL_03934 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPEIKGBL_03935 1.3e-28 yfkK S Belongs to the UPF0435 family
NPEIKGBL_03936 6.8e-207 ydiM EGP Major facilitator Superfamily
NPEIKGBL_03937 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
NPEIKGBL_03938 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NPEIKGBL_03939 1.1e-124 yfkO C nitroreductase
NPEIKGBL_03940 1.8e-133 treR K transcriptional
NPEIKGBL_03941 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NPEIKGBL_03942 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPEIKGBL_03943 1.5e-283 yfkQ EG Spore germination protein
NPEIKGBL_03944 5.1e-207 yfkR S spore germination
NPEIKGBL_03946 1.3e-193 E Spore germination protein
NPEIKGBL_03947 4.9e-252 agcS_1 E Sodium alanine symporter
NPEIKGBL_03948 6e-67 yhdN S Domain of unknown function (DUF1992)
NPEIKGBL_03949 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NPEIKGBL_03950 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NPEIKGBL_03951 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
NPEIKGBL_03952 5.3e-50 yflH S Protein of unknown function (DUF3243)
NPEIKGBL_03953 4.1e-19 yflI
NPEIKGBL_03954 4e-18 yflJ S Protein of unknown function (DUF2639)
NPEIKGBL_03955 6.4e-122 yflK S protein conserved in bacteria
NPEIKGBL_03956 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NPEIKGBL_03957 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NPEIKGBL_03958 4.6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NPEIKGBL_03959 8.5e-227 citM C Citrate transporter
NPEIKGBL_03960 3.1e-178 yflP S Tripartite tricarboxylate transporter family receptor
NPEIKGBL_03961 1.3e-117 citT T response regulator
NPEIKGBL_03962 7e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NPEIKGBL_03963 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
NPEIKGBL_03964 2.7e-238 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NPEIKGBL_03965 7.6e-58 yflT S Heat induced stress protein YflT
NPEIKGBL_03966 2.9e-24 S Protein of unknown function (DUF3212)
NPEIKGBL_03967 7.9e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NPEIKGBL_03968 6.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEIKGBL_03969 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPEIKGBL_03970 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NPEIKGBL_03971 6.1e-188 yfmJ S N-terminal domain of oxidoreductase
NPEIKGBL_03972 3.5e-79 yfmK 2.3.1.128 K acetyltransferase
NPEIKGBL_03973 1.7e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NPEIKGBL_03974 1.6e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPEIKGBL_03975 9.5e-209 yfmO EGP Major facilitator Superfamily
NPEIKGBL_03976 2.4e-69 yfmP K transcriptional
NPEIKGBL_03977 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
NPEIKGBL_03978 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPEIKGBL_03979 1.1e-113 yfmS NT chemotaxis protein
NPEIKGBL_03980 2.4e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPEIKGBL_03981 8.4e-241 yfnA E amino acid
NPEIKGBL_03982 1.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NPEIKGBL_03983 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
NPEIKGBL_03984 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
NPEIKGBL_03985 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NPEIKGBL_03986 2.4e-180 yfnF M Nucleotide-diphospho-sugar transferase
NPEIKGBL_03987 1.9e-172 yfnG 4.2.1.45 M dehydratase
NPEIKGBL_03988 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
NPEIKGBL_03989 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NPEIKGBL_03990 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NPEIKGBL_03991 3.6e-199 yetN S Protein of unknown function (DUF3900)
NPEIKGBL_03992 3.7e-207 yetM CH FAD binding domain
NPEIKGBL_03993 2.1e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
NPEIKGBL_03994 7.3e-156 yetK EG EamA-like transporter family
NPEIKGBL_03995 2.6e-104 yetJ S Belongs to the BI1 family
NPEIKGBL_03996 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
NPEIKGBL_03997 2.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPEIKGBL_03998 2.4e-34
NPEIKGBL_03999 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPEIKGBL_04000 4e-122 yetF S membrane
NPEIKGBL_04001 2.9e-254 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NPEIKGBL_04002 2.2e-162 lplC G Binding-protein-dependent transport system inner membrane component
NPEIKGBL_04003 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NPEIKGBL_04004 1.1e-289 lplA G Bacterial extracellular solute-binding protein
NPEIKGBL_04005 0.0 yetA
NPEIKGBL_04006 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NPEIKGBL_04007 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
NPEIKGBL_04008 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NPEIKGBL_04009 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NPEIKGBL_04010 6.3e-111 yesV S Protein of unknown function, DUF624
NPEIKGBL_04011 1.9e-126 yesU S Domain of unknown function (DUF1961)
NPEIKGBL_04012 5.7e-129 E GDSL-like Lipase/Acylhydrolase
NPEIKGBL_04013 0.0 yesS K Transcriptional regulator
NPEIKGBL_04014 1.9e-197 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NPEIKGBL_04015 3.5e-163 yesQ P Binding-protein-dependent transport system inner membrane component
NPEIKGBL_04016 2.3e-170 yesP G Binding-protein-dependent transport system inner membrane component
NPEIKGBL_04017 1.5e-247 yesO G Bacterial extracellular solute-binding protein
NPEIKGBL_04018 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
NPEIKGBL_04019 0.0 yesM 2.7.13.3 T Histidine kinase
NPEIKGBL_04020 4.4e-104 yesL S Protein of unknown function, DUF624
NPEIKGBL_04022 4.2e-103 yesJ K Acetyltransferase (GNAT) family
NPEIKGBL_04023 5.2e-104 cotJC P Spore Coat
NPEIKGBL_04024 1.5e-45 cotJB S CotJB protein
NPEIKGBL_04025 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NPEIKGBL_04026 1.2e-155 yesF GM NAD(P)H-binding
NPEIKGBL_04027 2.8e-81 yesE S SnoaL-like domain
NPEIKGBL_04028 1.6e-100 dhaR3 K Transcriptional regulator
NPEIKGBL_04030 2.7e-126 yeeN K transcriptional regulatory protein
NPEIKGBL_04032 6.7e-212 S Tetratricopeptide repeat
NPEIKGBL_04033 1.4e-63 S membrane
NPEIKGBL_04034 9.4e-52
NPEIKGBL_04035 2.1e-99 L endonuclease activity
NPEIKGBL_04037 9.3e-160 yobL S Bacterial EndoU nuclease
NPEIKGBL_04038 7.5e-17
NPEIKGBL_04040 1.1e-56 S Tetratricopeptide repeat
NPEIKGBL_04041 1.1e-35 S response regulator aspartate phosphatase
NPEIKGBL_04043 9.7e-27 XK26_06125 S Transcriptional Coactivator p15 (PC4)
NPEIKGBL_04044 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NPEIKGBL_04045 2.3e-86 hsdS 3.1.21.3 V DNA specificity domain
NPEIKGBL_04046 5.8e-251 hsdM 2.1.1.72 V Type I restriction-modification system
NPEIKGBL_04047 2.5e-77 K Helix-turn-helix
NPEIKGBL_04048 1.8e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPEIKGBL_04049 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NPEIKGBL_04050 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NPEIKGBL_04051 7.6e-144 yerO K Transcriptional regulator
NPEIKGBL_04052 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPEIKGBL_04053 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPEIKGBL_04054 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPEIKGBL_04055 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPEIKGBL_04056 1.6e-123 sapB S MgtC SapB transporter
NPEIKGBL_04057 3.9e-195 yerI S homoserine kinase type II (protein kinase fold)
NPEIKGBL_04058 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
NPEIKGBL_04059 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPEIKGBL_04060 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NPEIKGBL_04061 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NPEIKGBL_04063 2.2e-301 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NPEIKGBL_04064 4.8e-51 yerC S protein conserved in bacteria
NPEIKGBL_04065 1.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
NPEIKGBL_04066 0.0 yerA 3.5.4.2 F adenine deaminase
NPEIKGBL_04067 6e-27 S Protein of unknown function (DUF2892)
NPEIKGBL_04068 5.2e-229 yjeH E Amino acid permease
NPEIKGBL_04069 1e-72 K helix_turn_helix ASNC type
NPEIKGBL_04070 4.5e-233 purD 6.3.4.13 F Belongs to the GARS family
NPEIKGBL_04071 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NPEIKGBL_04072 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NPEIKGBL_04073 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NPEIKGBL_04074 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NPEIKGBL_04075 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPEIKGBL_04076 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPEIKGBL_04077 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPEIKGBL_04078 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NPEIKGBL_04079 8.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPEIKGBL_04080 4.2e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NPEIKGBL_04081 4.8e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NPEIKGBL_04082 8e-28 yebG S NETI protein
NPEIKGBL_04083 4e-93 yebE S UPF0316 protein
NPEIKGBL_04085 2.3e-118 yebC M Membrane
NPEIKGBL_04086 7.8e-212 pbuG S permease
NPEIKGBL_04087 1.4e-254 S Domain of unknown function (DUF4179)
NPEIKGBL_04088 2.9e-88 K Belongs to the sigma-70 factor family. ECF subfamily
NPEIKGBL_04089 2e-38
NPEIKGBL_04090 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NPEIKGBL_04091 0.0 yebA E COG1305 Transglutaminase-like enzymes
NPEIKGBL_04092 6.8e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NPEIKGBL_04093 3e-176 yeaC S COG0714 MoxR-like ATPases
NPEIKGBL_04094 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPEIKGBL_04095 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NPEIKGBL_04096 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NPEIKGBL_04097 9.4e-178 yeaA S Protein of unknown function (DUF4003)
NPEIKGBL_04098 6.8e-158 ydjP I Alpha/beta hydrolase family
NPEIKGBL_04099 1.2e-34 ydjO S Cold-inducible protein YdjO
NPEIKGBL_04101 1.6e-151 ydjN U Involved in the tonB-independent uptake of proteins
NPEIKGBL_04102 4.5e-64 ydjM M Lytic transglycolase
NPEIKGBL_04103 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NPEIKGBL_04104 3.9e-257 iolT EGP Major facilitator Superfamily
NPEIKGBL_04105 8e-196 S Ion transport 2 domain protein
NPEIKGBL_04106 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
NPEIKGBL_04107 1.1e-136 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NPEIKGBL_04108 4.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPEIKGBL_04109 5.6e-113 pspA KT Phage shock protein A

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)