ORF_ID e_value Gene_name EC_number CAZy COGs Description
MLNPHKMC_00001 1.4e-124 ywrJ
MLNPHKMC_00002 1.4e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLNPHKMC_00003 1.1e-169 alsR K LysR substrate binding domain
MLNPHKMC_00004 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MLNPHKMC_00005 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MLNPHKMC_00006 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
MLNPHKMC_00007 8e-48 ywsA S Protein of unknown function (DUF3892)
MLNPHKMC_00008 8.7e-93 batE T Sh3 type 3 domain protein
MLNPHKMC_00009 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MLNPHKMC_00010 3.5e-148 rbsC G Belongs to the binding-protein-dependent transport system permease family
MLNPHKMC_00011 8.6e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MLNPHKMC_00012 5.3e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MLNPHKMC_00013 2.5e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLNPHKMC_00014 5.2e-176 rbsR K transcriptional
MLNPHKMC_00015 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
MLNPHKMC_00016 8.6e-70 pgsC S biosynthesis protein
MLNPHKMC_00017 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MLNPHKMC_00018 3.6e-21 ywtC
MLNPHKMC_00019 2e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLNPHKMC_00020 4.2e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
MLNPHKMC_00021 2.3e-168 ywtF K Transcriptional regulator
MLNPHKMC_00022 1.3e-246 ywtG EGP Major facilitator Superfamily
MLNPHKMC_00023 9.3e-206 gerAC S Spore germination protein
MLNPHKMC_00024 8.4e-191 gerBB E Spore germination protein
MLNPHKMC_00025 3.7e-263 gerBA EG Spore germination protein
MLNPHKMC_00026 1.8e-186 pmi 5.3.1.8 G mannose-6-phosphate isomerase
MLNPHKMC_00027 1.2e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLNPHKMC_00028 2.4e-127 M Glycosyl transferase group 1 protein
MLNPHKMC_00029 2.8e-158 wbmJ M Glycosyl transferases group 1
MLNPHKMC_00031 1.8e-126 M DUF based on E. rectale Gene description (DUF3880)
MLNPHKMC_00032 2e-159 wecC 1.1.1.336 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLNPHKMC_00033 3.5e-129 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLNPHKMC_00034 5.6e-54 3.4.11.5 S alpha beta
MLNPHKMC_00035 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MLNPHKMC_00036 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MLNPHKMC_00037 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MLNPHKMC_00038 2e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MLNPHKMC_00039 9.2e-96 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLNPHKMC_00040 5.4e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MLNPHKMC_00041 1.1e-52 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MLNPHKMC_00042 1.2e-133 tagG GM Transport permease protein
MLNPHKMC_00043 1.8e-271 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MLNPHKMC_00044 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MLNPHKMC_00045 5.3e-119 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MLNPHKMC_00047 8.5e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MLNPHKMC_00048 1.8e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MLNPHKMC_00049 2.1e-35
MLNPHKMC_00050 6.8e-14 lytB 3.5.1.28 D Stage II sporulation protein
MLNPHKMC_00051 9e-265 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLNPHKMC_00052 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLNPHKMC_00053 7.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLNPHKMC_00054 1.1e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
MLNPHKMC_00055 1.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLNPHKMC_00056 3.7e-263 tuaE M Teichuronic acid biosynthesis protein
MLNPHKMC_00057 5.1e-114 tuaF M protein involved in exopolysaccharide biosynthesis
MLNPHKMC_00058 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
MLNPHKMC_00059 1.3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
MLNPHKMC_00060 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MLNPHKMC_00061 6e-163 yvhJ K Transcriptional regulator
MLNPHKMC_00062 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MLNPHKMC_00063 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MLNPHKMC_00064 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLNPHKMC_00065 2.1e-154 degV S protein conserved in bacteria
MLNPHKMC_00066 5.4e-264 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MLNPHKMC_00067 5.7e-46 comFB S Late competence development protein ComFB
MLNPHKMC_00068 4.7e-126 comFC S Phosphoribosyl transferase domain
MLNPHKMC_00069 7e-74 yvyF S flagellar protein
MLNPHKMC_00070 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
MLNPHKMC_00071 4.1e-78 flgN NOU FlgN protein
MLNPHKMC_00072 1.2e-264 flgK N flagellar hook-associated protein
MLNPHKMC_00073 1.3e-154 flgL N Belongs to the bacterial flagellin family
MLNPHKMC_00074 5.7e-50 yviE
MLNPHKMC_00075 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MLNPHKMC_00076 9.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MLNPHKMC_00077 1.4e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLNPHKMC_00078 1.2e-55 flaG N flagellar protein FlaG
MLNPHKMC_00079 1.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MLNPHKMC_00080 2.9e-69 fliS N flagellar protein FliS
MLNPHKMC_00081 1.9e-08 fliT S bacterial-type flagellum organization
MLNPHKMC_00082 1.8e-65
MLNPHKMC_00083 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MLNPHKMC_00084 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MLNPHKMC_00085 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MLNPHKMC_00086 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MLNPHKMC_00087 1e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
MLNPHKMC_00088 1.6e-123 ftsE D cell division ATP-binding protein FtsE
MLNPHKMC_00089 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MLNPHKMC_00090 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MLNPHKMC_00091 5.3e-56 swrA S Swarming motility protein
MLNPHKMC_00092 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLNPHKMC_00093 2.8e-225 yvkA EGP Major facilitator Superfamily
MLNPHKMC_00094 7e-101 yvkB K Transcriptional regulator
MLNPHKMC_00095 0.0 yvkC 2.7.9.2 GT Phosphotransferase
MLNPHKMC_00096 1.2e-30 csbA S protein conserved in bacteria
MLNPHKMC_00097 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MLNPHKMC_00098 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MLNPHKMC_00099 9.2e-78 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLNPHKMC_00100 5.7e-33 yvkN
MLNPHKMC_00101 1.8e-48 yvlA
MLNPHKMC_00102 2.4e-166 yvlB S Putative adhesin
MLNPHKMC_00103 2.6e-26 pspB KT PspC domain
MLNPHKMC_00104 1.2e-50 yvlD S Membrane
MLNPHKMC_00105 2.7e-203 yvmA EGP Major facilitator Superfamily
MLNPHKMC_00106 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
MLNPHKMC_00107 3e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MLNPHKMC_00108 1.2e-227 cypX 1.14.15.13 C Cytochrome P450
MLNPHKMC_00109 3.6e-71 adcR K helix_turn_helix multiple antibiotic resistance protein
MLNPHKMC_00110 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
MLNPHKMC_00111 5.2e-133 yvoA K transcriptional
MLNPHKMC_00112 6.2e-126 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLNPHKMC_00113 5.9e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MLNPHKMC_00114 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MLNPHKMC_00115 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLNPHKMC_00116 2.4e-162 yvoD P COG0370 Fe2 transport system protein B
MLNPHKMC_00117 9.4e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MLNPHKMC_00118 9.6e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MLNPHKMC_00119 1.3e-117 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
MLNPHKMC_00120 1e-139 yvpB NU protein conserved in bacteria
MLNPHKMC_00121 1.2e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MLNPHKMC_00122 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MLNPHKMC_00123 3.4e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MLNPHKMC_00124 1.4e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MLNPHKMC_00125 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MLNPHKMC_00126 2.3e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MLNPHKMC_00127 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MLNPHKMC_00128 2.2e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MLNPHKMC_00129 6.3e-78
MLNPHKMC_00130 5.9e-253
MLNPHKMC_00132 0.0 msbA2 3.6.3.44 V ABC transporter
MLNPHKMC_00133 2.9e-276 S COG0457 FOG TPR repeat
MLNPHKMC_00134 2.1e-98 usp CBM50 M protein conserved in bacteria
MLNPHKMC_00135 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MLNPHKMC_00136 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MLNPHKMC_00137 5.7e-166 rapZ S Displays ATPase and GTPase activities
MLNPHKMC_00138 2.8e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MLNPHKMC_00139 1.4e-170 whiA K May be required for sporulation
MLNPHKMC_00140 1.6e-36 crh G Phosphocarrier protein Chr
MLNPHKMC_00141 5.4e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
MLNPHKMC_00142 3.9e-33
MLNPHKMC_00143 1.8e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLNPHKMC_00144 2.2e-196 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MLNPHKMC_00145 5.6e-141 yvcR V ABC transporter, ATP-binding protein
MLNPHKMC_00146 0.0 yxdM V ABC transporter (permease)
MLNPHKMC_00147 8.1e-182 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLNPHKMC_00148 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MLNPHKMC_00149 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
MLNPHKMC_00150 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
MLNPHKMC_00151 1.2e-105 yvdD 3.2.2.10 S Belongs to the LOG family
MLNPHKMC_00152 8.8e-173 yvdE K Transcriptional regulator
MLNPHKMC_00153 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MLNPHKMC_00154 1.2e-233 mdxE G COG2182 Maltose-binding periplasmic proteins domains
MLNPHKMC_00155 3.4e-244 malC P COG1175 ABC-type sugar transport systems, permease components
MLNPHKMC_00156 8.6e-148 malD P transport
MLNPHKMC_00157 1.2e-155 malA S Protein of unknown function (DUF1189)
MLNPHKMC_00158 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MLNPHKMC_00159 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MLNPHKMC_00160 2e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MLNPHKMC_00161 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MLNPHKMC_00163 8.3e-93 yvdQ S Protein of unknown function (DUF3231)
MLNPHKMC_00164 4.1e-50 sugE P Small Multidrug Resistance protein
MLNPHKMC_00165 1.5e-50 ykkC P Small Multidrug Resistance protein
MLNPHKMC_00166 2.4e-104 yvdT K Transcriptional regulator
MLNPHKMC_00167 1.8e-295 yveA E amino acid
MLNPHKMC_00168 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MLNPHKMC_00169 1.3e-273 sacB 2.4.1.10 GH68 M levansucrase activity
MLNPHKMC_00170 5e-262 pbpE V Beta-lactamase
MLNPHKMC_00171 8.9e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MLNPHKMC_00172 1.9e-72 MA20_18690 S Protein of unknown function (DUF3237)
MLNPHKMC_00173 4.6e-93 padC Q Phenolic acid decarboxylase
MLNPHKMC_00175 2e-285 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MLNPHKMC_00176 2.8e-76 slr K transcriptional
MLNPHKMC_00177 8.9e-122 ywqC M biosynthesis protein
MLNPHKMC_00178 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
MLNPHKMC_00179 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MLNPHKMC_00180 1.2e-219 epsD GT4 M Glycosyl transferase 4-like
MLNPHKMC_00181 1.3e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLNPHKMC_00182 8.4e-218 epsF GT4 M Glycosyl transferases group 1
MLNPHKMC_00183 1.8e-206 epsG S EpsG family
MLNPHKMC_00184 5.8e-194 epsH GT2 S Glycosyltransferase like family 2
MLNPHKMC_00185 9.2e-203 epsI GM pyruvyl transferase
MLNPHKMC_00186 2.6e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
MLNPHKMC_00187 4.1e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLNPHKMC_00188 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLNPHKMC_00189 1e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
MLNPHKMC_00190 1.3e-218 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
MLNPHKMC_00191 1.3e-184 yvfF GM Exopolysaccharide biosynthesis protein
MLNPHKMC_00192 1e-31 yvfG S YvfG protein
MLNPHKMC_00193 1.2e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MLNPHKMC_00194 2.6e-308 yvfH C L-lactate permease
MLNPHKMC_00195 2.3e-112 yvfI K COG2186 Transcriptional regulators
MLNPHKMC_00196 4e-184 lacR K Transcriptional regulator
MLNPHKMC_00197 1e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
MLNPHKMC_00198 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
MLNPHKMC_00199 7.9e-149 ganQ P transport
MLNPHKMC_00200 0.0 lacA 3.2.1.23 G beta-galactosidase
MLNPHKMC_00201 9.8e-252 galA 3.2.1.89 G arabinogalactan
MLNPHKMC_00202 2.4e-199 rsbU 3.1.3.3 T response regulator
MLNPHKMC_00203 4.4e-157 rsbQ S Alpha/beta hydrolase family
MLNPHKMC_00205 4.4e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
MLNPHKMC_00206 4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
MLNPHKMC_00207 2.4e-193 desK 2.7.13.3 T Histidine kinase
MLNPHKMC_00208 6.5e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLNPHKMC_00209 2.6e-31 K Transcriptional regulator PadR-like family
MLNPHKMC_00210 1.3e-44 S Protein of unknown function (DUF2812)
MLNPHKMC_00211 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLNPHKMC_00212 8.6e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MLNPHKMC_00213 7.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLNPHKMC_00214 8.6e-190 yvbX S Glycosyl hydrolase
MLNPHKMC_00215 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
MLNPHKMC_00216 3.6e-155 yvbV EG EamA-like transporter family
MLNPHKMC_00217 5.1e-159 yvbU K Transcriptional regulator
MLNPHKMC_00218 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLNPHKMC_00219 5.5e-203 araR K transcriptional
MLNPHKMC_00220 1.1e-251 araE EGP Major facilitator Superfamily
MLNPHKMC_00221 3.5e-183 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLNPHKMC_00222 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLNPHKMC_00223 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MLNPHKMC_00224 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MLNPHKMC_00225 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MLNPHKMC_00226 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MLNPHKMC_00227 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
MLNPHKMC_00228 0.0 tcaA S response to antibiotic
MLNPHKMC_00229 1e-122 exoY M Membrane
MLNPHKMC_00230 6.2e-111 yvbH S YvbH-like oligomerisation region
MLNPHKMC_00231 2.1e-101 yvbG U UPF0056 membrane protein
MLNPHKMC_00232 3.9e-96 yvbF K Belongs to the GbsR family
MLNPHKMC_00233 1.3e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLNPHKMC_00234 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLNPHKMC_00235 1.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLNPHKMC_00236 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLNPHKMC_00237 3.3e-60 yvbF K Belongs to the GbsR family
MLNPHKMC_00238 2.8e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLNPHKMC_00239 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLNPHKMC_00240 1.2e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLNPHKMC_00241 4.7e-104 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLNPHKMC_00242 3.7e-196 spaB S Lantibiotic dehydratase, C terminus
MLNPHKMC_00243 1.3e-156 spaT V ABC transporter
MLNPHKMC_00244 2.4e-96 spaC2 V PFAM Lanthionine synthetase
MLNPHKMC_00245 1.1e-09 S Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
MLNPHKMC_00247 4.2e-103 mutF V ABC transporter, ATP-binding protein
MLNPHKMC_00248 1.5e-87 spaE S ABC-2 family transporter protein
MLNPHKMC_00249 1.7e-81 mutG S ABC-2 family transporter protein
MLNPHKMC_00250 2.5e-105 K Transcriptional regulatory protein, C terminal
MLNPHKMC_00251 2.3e-153 T His Kinase A (phosphoacceptor) domain
MLNPHKMC_00252 3.2e-218 NT chemotaxis protein
MLNPHKMC_00253 2.2e-54 yodB K transcriptional
MLNPHKMC_00254 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
MLNPHKMC_00255 1.2e-68 K transcriptional
MLNPHKMC_00256 9.8e-36 yvzC K Transcriptional
MLNPHKMC_00257 7.7e-151 yvaM S Serine aminopeptidase, S33
MLNPHKMC_00258 2.4e-23 secG U Preprotein translocase subunit SecG
MLNPHKMC_00259 5.6e-143 est 3.1.1.1 S Carboxylesterase
MLNPHKMC_00260 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MLNPHKMC_00261 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MLNPHKMC_00263 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLNPHKMC_00264 3.3e-98 K Bacterial regulatory proteins, tetR family
MLNPHKMC_00265 4.5e-53 yvaE P Small Multidrug Resistance protein
MLNPHKMC_00266 5.7e-73 yvaD S Family of unknown function (DUF5360)
MLNPHKMC_00267 0.0 yvaC S Fusaric acid resistance protein-like
MLNPHKMC_00268 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLNPHKMC_00269 7.6e-194 yvaA 1.1.1.371 S Oxidoreductase
MLNPHKMC_00270 2.2e-48 csoR S transcriptional
MLNPHKMC_00271 1.3e-28 copZ P Copper resistance protein CopZ
MLNPHKMC_00272 0.0 copA 3.6.3.54 P P-type ATPase
MLNPHKMC_00273 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MLNPHKMC_00274 1.6e-104 bdbD O Thioredoxin
MLNPHKMC_00275 6.5e-72 bdbC O Required for disulfide bond formation in some proteins
MLNPHKMC_00276 1.6e-106 yvgT S membrane
MLNPHKMC_00278 0.0 helD 3.6.4.12 L DNA helicase
MLNPHKMC_00279 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MLNPHKMC_00280 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MLNPHKMC_00281 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MLNPHKMC_00282 5.4e-86 yvgO
MLNPHKMC_00283 1.1e-155 yvgN S reductase
MLNPHKMC_00284 1.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
MLNPHKMC_00285 3.5e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MLNPHKMC_00286 2.4e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
MLNPHKMC_00287 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLNPHKMC_00288 2.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
MLNPHKMC_00289 6.5e-16 S Small spore protein J (Spore_SspJ)
MLNPHKMC_00290 4.9e-236 yvsH E Arginine ornithine antiporter
MLNPHKMC_00292 1.2e-177 fhuD P ABC transporter
MLNPHKMC_00293 6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLNPHKMC_00294 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLNPHKMC_00295 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
MLNPHKMC_00296 6.9e-175 M Efflux transporter rnd family, mfp subunit
MLNPHKMC_00297 7.9e-123 macB V ABC transporter, ATP-binding protein
MLNPHKMC_00298 8.9e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
MLNPHKMC_00299 1.3e-64 yvrL S Regulatory protein YrvL
MLNPHKMC_00300 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
MLNPHKMC_00301 2.4e-19 S YvrJ protein family
MLNPHKMC_00302 1.9e-98 yvrI K RNA polymerase
MLNPHKMC_00303 7.2e-23
MLNPHKMC_00304 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLNPHKMC_00305 0.0 T PhoQ Sensor
MLNPHKMC_00306 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
MLNPHKMC_00307 4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLNPHKMC_00308 2.6e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MLNPHKMC_00309 1.7e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLNPHKMC_00310 2.5e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MLNPHKMC_00311 5.5e-101 yvqK 2.5.1.17 S Adenosyltransferase
MLNPHKMC_00312 5.9e-225 yvqJ EGP Major facilitator Superfamily
MLNPHKMC_00313 5.6e-62 liaI S membrane
MLNPHKMC_00314 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MLNPHKMC_00315 7.4e-126 liaG S Putative adhesin
MLNPHKMC_00316 3.6e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MLNPHKMC_00317 1.3e-185 vraS 2.7.13.3 T Histidine kinase
MLNPHKMC_00318 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLNPHKMC_00319 2.9e-183 gerAC S Spore germination B3/ GerAC like, C-terminal
MLNPHKMC_00320 3.8e-196 gerAB E Spore germination protein
MLNPHKMC_00321 3.1e-246 gerAA EG Spore germination protein
MLNPHKMC_00322 3.9e-24 S Protein of unknown function (DUF3970)
MLNPHKMC_00323 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MLNPHKMC_00324 4.3e-158 yuxN K Transcriptional regulator
MLNPHKMC_00325 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
MLNPHKMC_00326 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLNPHKMC_00327 3.8e-233 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLNPHKMC_00328 2.7e-79 dps P Ferritin-like domain
MLNPHKMC_00329 4.2e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLNPHKMC_00330 7.2e-301 pepF2 E COG1164 Oligoendopeptidase F
MLNPHKMC_00331 2.3e-67 S YusW-like protein
MLNPHKMC_00332 3.9e-153 yusV 3.6.3.34 HP ABC transporter
MLNPHKMC_00333 1.1e-46 yusU S Protein of unknown function (DUF2573)
MLNPHKMC_00334 2.2e-157 yusT K LysR substrate binding domain
MLNPHKMC_00335 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLNPHKMC_00336 4.6e-64 yusQ S Tautomerase enzyme
MLNPHKMC_00337 1.2e-291 yusP P Major facilitator superfamily
MLNPHKMC_00338 3.9e-73 yusO K Iron dependent repressor, N-terminal DNA binding domain
MLNPHKMC_00339 5.4e-53 yusN M Coat F domain
MLNPHKMC_00340 5.1e-40
MLNPHKMC_00341 8.4e-165 fadM E Proline dehydrogenase
MLNPHKMC_00342 8.1e-09 S YuzL-like protein
MLNPHKMC_00343 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MLNPHKMC_00344 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
MLNPHKMC_00345 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MLNPHKMC_00346 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
MLNPHKMC_00347 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MLNPHKMC_00348 1.1e-39 yusG S Protein of unknown function (DUF2553)
MLNPHKMC_00349 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
MLNPHKMC_00350 9.5e-55 traF CO Thioredoxin
MLNPHKMC_00351 9.3e-56 yusD S SCP-2 sterol transfer family
MLNPHKMC_00352 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLNPHKMC_00353 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
MLNPHKMC_00354 9.4e-147 metQ P Belongs to the NlpA lipoprotein family
MLNPHKMC_00355 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MLNPHKMC_00356 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MLNPHKMC_00357 4.5e-244 sufD O assembly protein SufD
MLNPHKMC_00358 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MLNPHKMC_00359 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MLNPHKMC_00360 3.5e-271 sufB O FeS cluster assembly
MLNPHKMC_00361 3.3e-43 K helix_turn_helix, Arsenical Resistance Operon Repressor
MLNPHKMC_00362 1.3e-41 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLNPHKMC_00363 3.9e-41
MLNPHKMC_00365 2.7e-205 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MLNPHKMC_00366 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
MLNPHKMC_00367 8.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MLNPHKMC_00368 2.7e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
MLNPHKMC_00369 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
MLNPHKMC_00370 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
MLNPHKMC_00371 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
MLNPHKMC_00372 3.3e-135 yurK K UTRA
MLNPHKMC_00373 2.9e-204 msmX P Belongs to the ABC transporter superfamily
MLNPHKMC_00374 1.1e-166 bsn L Ribonuclease
MLNPHKMC_00375 1.7e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MLNPHKMC_00376 5.6e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MLNPHKMC_00377 2.6e-183 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MLNPHKMC_00378 1.7e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
MLNPHKMC_00379 2.1e-146 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MLNPHKMC_00380 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MLNPHKMC_00381 6.9e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MLNPHKMC_00383 1.1e-53 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MLNPHKMC_00384 7.1e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MLNPHKMC_00385 1.4e-221 pbuX F xanthine
MLNPHKMC_00386 2e-231 pbuX F Permease family
MLNPHKMC_00387 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
MLNPHKMC_00388 2.5e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MLNPHKMC_00389 1.4e-59 yunG
MLNPHKMC_00390 1.3e-170 yunF S Protein of unknown function DUF72
MLNPHKMC_00391 1e-140 yunE S membrane transporter protein
MLNPHKMC_00392 5.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MLNPHKMC_00393 1.1e-47 yunC S Domain of unknown function (DUF1805)
MLNPHKMC_00394 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
MLNPHKMC_00395 9.9e-196 lytH M Peptidase, M23
MLNPHKMC_00396 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MLNPHKMC_00397 2e-109 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLNPHKMC_00398 9.7e-48 yutD S protein conserved in bacteria
MLNPHKMC_00399 8.6e-75 yutE S Protein of unknown function DUF86
MLNPHKMC_00400 3.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MLNPHKMC_00401 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MLNPHKMC_00402 6.5e-198 yutH S Spore coat protein
MLNPHKMC_00403 7.9e-241 hom 1.1.1.3 E homoserine dehydrogenase
MLNPHKMC_00404 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MLNPHKMC_00405 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MLNPHKMC_00406 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
MLNPHKMC_00407 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
MLNPHKMC_00408 3e-56 yuzD S protein conserved in bacteria
MLNPHKMC_00409 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
MLNPHKMC_00410 3.2e-39 yuzB S Belongs to the UPF0349 family
MLNPHKMC_00411 1.2e-198 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLNPHKMC_00412 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MLNPHKMC_00413 3.7e-63 erpA S Belongs to the HesB IscA family
MLNPHKMC_00414 9.6e-73 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLNPHKMC_00415 1.9e-115 paiB K Putative FMN-binding domain
MLNPHKMC_00416 3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MLNPHKMC_00418 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
MLNPHKMC_00419 6.1e-235 yumB 1.6.99.3 C NADH dehydrogenase
MLNPHKMC_00420 1.9e-26 yuiB S Putative membrane protein
MLNPHKMC_00421 4.7e-117 yuiC S protein conserved in bacteria
MLNPHKMC_00422 1.2e-77 yuiD S protein conserved in bacteria
MLNPHKMC_00423 7.1e-278 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MLNPHKMC_00424 3.9e-211 yuiF S antiporter
MLNPHKMC_00425 1.1e-93 bioY S Biotin biosynthesis protein
MLNPHKMC_00426 2.2e-121 yuiH S Oxidoreductase molybdopterin binding domain
MLNPHKMC_00427 1.1e-166 besA S Putative esterase
MLNPHKMC_00428 1.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLNPHKMC_00429 2.1e-224 entC 5.4.4.2 HQ Isochorismate synthase
MLNPHKMC_00430 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
MLNPHKMC_00431 3.1e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
MLNPHKMC_00432 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLNPHKMC_00433 5e-36 mbtH S MbtH-like protein
MLNPHKMC_00434 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
MLNPHKMC_00435 1.8e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MLNPHKMC_00436 4.7e-227 yukF QT Transcriptional regulator
MLNPHKMC_00437 2.8e-45 esxA S Belongs to the WXG100 family
MLNPHKMC_00438 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
MLNPHKMC_00439 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
MLNPHKMC_00440 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MLNPHKMC_00441 0.0 esaA S type VII secretion protein EsaA
MLNPHKMC_00442 3.3e-64 yueC S Family of unknown function (DUF5383)
MLNPHKMC_00443 1.1e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLNPHKMC_00444 1.4e-95 yueE S phosphohydrolase
MLNPHKMC_00445 2.9e-24 S Protein of unknown function (DUF2642)
MLNPHKMC_00446 3.4e-70 S Protein of unknown function (DUF2283)
MLNPHKMC_00447 3.2e-190 yueF S transporter activity
MLNPHKMC_00448 6.6e-31 yueG S Spore germination protein gerPA/gerPF
MLNPHKMC_00449 7.4e-39 yueH S YueH-like protein
MLNPHKMC_00450 1.8e-66 yueI S Protein of unknown function (DUF1694)
MLNPHKMC_00451 2.8e-102 pncA Q COG1335 Amidases related to nicotinamidase
MLNPHKMC_00452 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLNPHKMC_00453 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
MLNPHKMC_00454 1.1e-22 yuzC
MLNPHKMC_00456 5e-128 comQ H Belongs to the FPP GGPP synthase family
MLNPHKMC_00458 3.8e-254 comP 2.7.13.3 T Histidine kinase
MLNPHKMC_00459 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLNPHKMC_00460 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
MLNPHKMC_00461 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MLNPHKMC_00462 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLNPHKMC_00463 9.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLNPHKMC_00464 5.4e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLNPHKMC_00465 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLNPHKMC_00466 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLNPHKMC_00467 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MLNPHKMC_00468 3.2e-14
MLNPHKMC_00469 1.8e-232 maeN C COG3493 Na citrate symporter
MLNPHKMC_00470 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
MLNPHKMC_00471 1.4e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
MLNPHKMC_00472 7.8e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MLNPHKMC_00473 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MLNPHKMC_00474 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
MLNPHKMC_00475 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MLNPHKMC_00476 6.3e-78 yufK S Family of unknown function (DUF5366)
MLNPHKMC_00477 6.3e-75 yuxK S protein conserved in bacteria
MLNPHKMC_00478 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
MLNPHKMC_00479 3.8e-185 yuxJ EGP Major facilitator Superfamily
MLNPHKMC_00481 4.2e-115 kapD L the KinA pathway to sporulation
MLNPHKMC_00482 2.2e-69 kapB G Kinase associated protein B
MLNPHKMC_00483 1e-232 T PhoQ Sensor
MLNPHKMC_00484 4.9e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MLNPHKMC_00485 4.6e-39 yugE S Domain of unknown function (DUF1871)
MLNPHKMC_00486 4.9e-156 yugF I Hydrolase
MLNPHKMC_00487 1.6e-85 alaR K Transcriptional regulator
MLNPHKMC_00488 2.6e-197 yugH 2.6.1.1 E Aminotransferase
MLNPHKMC_00489 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MLNPHKMC_00490 1.1e-34 yuzA S Domain of unknown function (DUF378)
MLNPHKMC_00491 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MLNPHKMC_00492 1.1e-228 yugK C Dehydrogenase
MLNPHKMC_00493 7.1e-261 pgi 5.3.1.9 G Belongs to the GPI family
MLNPHKMC_00495 1.3e-72 yugN S YugN-like family
MLNPHKMC_00496 2.2e-182 yugO P COG1226 Kef-type K transport systems
MLNPHKMC_00497 1.1e-53 mstX S Membrane-integrating protein Mistic
MLNPHKMC_00498 7.4e-37
MLNPHKMC_00499 1.9e-116 yugP S Zn-dependent protease
MLNPHKMC_00500 3.8e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
MLNPHKMC_00501 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MLNPHKMC_00502 2.1e-72 yugU S Uncharacterised protein family UPF0047
MLNPHKMC_00503 1e-35
MLNPHKMC_00504 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
MLNPHKMC_00505 7.1e-225 mcpA NT chemotaxis protein
MLNPHKMC_00506 3.1e-220 mcpA NT chemotaxis protein
MLNPHKMC_00507 1.2e-293 mcpA NT chemotaxis protein
MLNPHKMC_00508 1.1e-238 mcpA NT chemotaxis protein
MLNPHKMC_00509 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
MLNPHKMC_00510 5e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
MLNPHKMC_00511 9.7e-280 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MLNPHKMC_00512 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MLNPHKMC_00513 2e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MLNPHKMC_00514 1.7e-182 ygjR S Oxidoreductase
MLNPHKMC_00515 9.1e-196 yubA S transporter activity
MLNPHKMC_00516 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MLNPHKMC_00518 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
MLNPHKMC_00519 1.9e-273 yubD P Major Facilitator Superfamily
MLNPHKMC_00520 3.2e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLNPHKMC_00521 1e-38 yiaA S yiaA/B two helix domain
MLNPHKMC_00522 1.6e-236 ktrB P Potassium
MLNPHKMC_00523 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
MLNPHKMC_00524 2.2e-91 yuaB
MLNPHKMC_00525 1.3e-93 yuaC K Belongs to the GbsR family
MLNPHKMC_00526 2e-280 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MLNPHKMC_00527 3.2e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
MLNPHKMC_00528 1.1e-106 yuaD
MLNPHKMC_00529 3.9e-84 yuaE S DinB superfamily
MLNPHKMC_00530 1.9e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MLNPHKMC_00531 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
MLNPHKMC_00532 1.4e-92 M1-753 M FR47-like protein
MLNPHKMC_00533 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
MLNPHKMC_00534 3.4e-39 S COG NOG14552 non supervised orthologous group
MLNPHKMC_00539 2e-08
MLNPHKMC_00546 1.3e-09
MLNPHKMC_00547 7.8e-08
MLNPHKMC_00556 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MLNPHKMC_00557 2.3e-196 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MLNPHKMC_00558 4.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
MLNPHKMC_00559 2.5e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MLNPHKMC_00560 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MLNPHKMC_00561 1.4e-75 tspO T membrane
MLNPHKMC_00562 3.7e-204 cotI S Spore coat protein
MLNPHKMC_00563 6.9e-217 cotSA M Glycosyl transferases group 1
MLNPHKMC_00564 1.6e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
MLNPHKMC_00566 4.8e-232 ytcC M Glycosyltransferase Family 4
MLNPHKMC_00567 6.3e-179 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
MLNPHKMC_00568 5.4e-242 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLNPHKMC_00569 6.9e-150 galU 2.7.7.9 M Nucleotidyl transferase
MLNPHKMC_00570 2.6e-132 dksA T COG1734 DnaK suppressor protein
MLNPHKMC_00571 2.3e-270 menF 5.4.4.2 HQ Isochorismate synthase
MLNPHKMC_00572 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MLNPHKMC_00573 1e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MLNPHKMC_00574 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MLNPHKMC_00575 3.9e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MLNPHKMC_00576 1e-212 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MLNPHKMC_00577 4.4e-169 troA P Belongs to the bacterial solute-binding protein 9 family
MLNPHKMC_00578 3.6e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MLNPHKMC_00579 1.3e-230 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MLNPHKMC_00580 9.1e-148 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MLNPHKMC_00581 1.1e-24 S Domain of Unknown Function (DUF1540)
MLNPHKMC_00582 4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MLNPHKMC_00583 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
MLNPHKMC_00584 3.6e-41 rpmE2 J Ribosomal protein L31
MLNPHKMC_00585 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MLNPHKMC_00586 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MLNPHKMC_00587 1.1e-72 ytkA S YtkA-like
MLNPHKMC_00589 2.1e-76 dps P Belongs to the Dps family
MLNPHKMC_00590 7e-63 ytkC S Bacteriophage holin family
MLNPHKMC_00591 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MLNPHKMC_00592 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MLNPHKMC_00593 3.2e-144 ytlC P ABC transporter
MLNPHKMC_00594 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MLNPHKMC_00595 2.1e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MLNPHKMC_00596 1.2e-38 ytmB S Protein of unknown function (DUF2584)
MLNPHKMC_00597 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MLNPHKMC_00598 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MLNPHKMC_00599 0.0 asnB 6.3.5.4 E Asparagine synthase
MLNPHKMC_00600 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
MLNPHKMC_00601 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MLNPHKMC_00602 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
MLNPHKMC_00603 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MLNPHKMC_00604 8.2e-105 ytqB J Putative rRNA methylase
MLNPHKMC_00605 4e-189 yhcC S Fe-S oxidoreductase
MLNPHKMC_00606 6.7e-41 ytzC S Protein of unknown function (DUF2524)
MLNPHKMC_00608 5.1e-66 ytrA K GntR family transcriptional regulator
MLNPHKMC_00609 4.2e-161 ytrB P abc transporter atp-binding protein
MLNPHKMC_00610 2e-164 P ABC-2 family transporter protein
MLNPHKMC_00611 6.3e-150
MLNPHKMC_00612 9.1e-127 ytrE V ABC transporter, ATP-binding protein
MLNPHKMC_00613 3.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
MLNPHKMC_00614 7.4e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLNPHKMC_00615 2.1e-185 T PhoQ Sensor
MLNPHKMC_00616 2.8e-137 bceA V ABC transporter, ATP-binding protein
MLNPHKMC_00617 0.0 bceB V ABC transporter (permease)
MLNPHKMC_00618 1.3e-41 yttA 2.7.13.3 S Pfam Transposase IS66
MLNPHKMC_00619 1.3e-210 yttB EGP Major facilitator Superfamily
MLNPHKMC_00620 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MLNPHKMC_00621 7.7e-55 ytvB S Protein of unknown function (DUF4257)
MLNPHKMC_00622 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MLNPHKMC_00623 2.1e-51 ytwF P Sulfurtransferase
MLNPHKMC_00624 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MLNPHKMC_00625 8.3e-143 amyC P ABC transporter (permease)
MLNPHKMC_00626 6.2e-168 amyD P ABC transporter
MLNPHKMC_00627 2.1e-246 msmE G Bacterial extracellular solute-binding protein
MLNPHKMC_00628 2.6e-186 msmR K Transcriptional regulator
MLNPHKMC_00629 4.1e-172 ytaP S Acetyl xylan esterase (AXE1)
MLNPHKMC_00630 2e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MLNPHKMC_00631 1.5e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MLNPHKMC_00632 9.3e-217 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLNPHKMC_00633 1.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MLNPHKMC_00634 9.3e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MLNPHKMC_00635 1.7e-218 bioI 1.14.14.46 C Cytochrome P450
MLNPHKMC_00636 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
MLNPHKMC_00637 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
MLNPHKMC_00638 1.5e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
MLNPHKMC_00639 0.0 ytdP K Transcriptional regulator
MLNPHKMC_00640 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MLNPHKMC_00641 1e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MLNPHKMC_00642 1.1e-71 yteS G transport
MLNPHKMC_00643 8.6e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
MLNPHKMC_00644 1.7e-114 yteU S Integral membrane protein
MLNPHKMC_00645 3.1e-26 yteV S Sporulation protein Cse60
MLNPHKMC_00646 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MLNPHKMC_00647 5.3e-231 ytfP S HI0933-like protein
MLNPHKMC_00648 4.2e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLNPHKMC_00649 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MLNPHKMC_00650 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MLNPHKMC_00651 4e-130 ythP V ABC transporter
MLNPHKMC_00652 2.4e-201 ythQ U Bacterial ABC transporter protein EcsB
MLNPHKMC_00653 2.1e-225 pbuO S permease
MLNPHKMC_00654 7.1e-272 pepV 3.5.1.18 E Dipeptidase
MLNPHKMC_00655 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MLNPHKMC_00656 1.2e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MLNPHKMC_00657 1.3e-165 ytlQ
MLNPHKMC_00658 2.5e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MLNPHKMC_00659 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MLNPHKMC_00660 1.4e-150 ytmP 2.7.1.89 M Phosphotransferase
MLNPHKMC_00661 2e-45 ytzH S YtzH-like protein
MLNPHKMC_00662 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MLNPHKMC_00663 7.1e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MLNPHKMC_00664 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
MLNPHKMC_00665 2.2e-51 ytzB S small secreted protein
MLNPHKMC_00666 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MLNPHKMC_00667 1e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MLNPHKMC_00668 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MLNPHKMC_00669 9.8e-149 ytpQ S Belongs to the UPF0354 family
MLNPHKMC_00670 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLNPHKMC_00671 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MLNPHKMC_00672 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MLNPHKMC_00673 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLNPHKMC_00674 6.6e-17 ytxH S COG4980 Gas vesicle protein
MLNPHKMC_00675 2.8e-54 ytxJ O Protein of unknown function (DUF2847)
MLNPHKMC_00676 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MLNPHKMC_00677 1.7e-182 ccpA K catabolite control protein A
MLNPHKMC_00678 2.1e-146 motA N flagellar motor
MLNPHKMC_00679 4e-125 motS N Flagellar motor protein
MLNPHKMC_00680 6.1e-224 acuC BQ histone deacetylase
MLNPHKMC_00681 3.5e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
MLNPHKMC_00682 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MLNPHKMC_00683 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLNPHKMC_00684 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLNPHKMC_00686 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MLNPHKMC_00687 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MLNPHKMC_00688 6.5e-87 ytsP 1.8.4.14 T GAF domain-containing protein
MLNPHKMC_00689 1e-108 yttP K Transcriptional regulator
MLNPHKMC_00690 5.9e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MLNPHKMC_00691 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MLNPHKMC_00692 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
MLNPHKMC_00693 5e-207 iscS2 2.8.1.7 E Cysteine desulfurase
MLNPHKMC_00694 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLNPHKMC_00695 2e-29 sspB S spore protein
MLNPHKMC_00696 2.9e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLNPHKMC_00697 0.0 ytcJ S amidohydrolase
MLNPHKMC_00698 8.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLNPHKMC_00699 3.5e-180 sppA OU signal peptide peptidase SppA
MLNPHKMC_00700 9.4e-86 yteJ S RDD family
MLNPHKMC_00701 1.6e-110 ytfI S Protein of unknown function (DUF2953)
MLNPHKMC_00702 8.7e-70 ytfJ S Sporulation protein YtfJ
MLNPHKMC_00703 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MLNPHKMC_00704 7e-165 ytxK 2.1.1.72 L DNA methylase
MLNPHKMC_00705 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLNPHKMC_00706 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MLNPHKMC_00707 3.9e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MLNPHKMC_00708 1.3e-265 argH 4.3.2.1 E argininosuccinate lyase
MLNPHKMC_00710 1.4e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLNPHKMC_00711 1.7e-130 ytkL S Belongs to the UPF0173 family
MLNPHKMC_00712 8e-241 ytoI K transcriptional regulator containing CBS domains
MLNPHKMC_00713 6.9e-47 ytpI S YtpI-like protein
MLNPHKMC_00714 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MLNPHKMC_00715 9.2e-29
MLNPHKMC_00716 8.2e-69 ytrI
MLNPHKMC_00717 3.2e-56 ytrH S Sporulation protein YtrH
MLNPHKMC_00718 0.0 dnaE 2.7.7.7 L DNA polymerase
MLNPHKMC_00719 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
MLNPHKMC_00720 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MLNPHKMC_00721 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MLNPHKMC_00722 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MLNPHKMC_00723 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MLNPHKMC_00724 1.6e-61 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MLNPHKMC_00725 4.4e-192 ytvI S sporulation integral membrane protein YtvI
MLNPHKMC_00726 1.1e-70 yeaL S membrane
MLNPHKMC_00727 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
MLNPHKMC_00728 4.1e-242 icd 1.1.1.42 C isocitrate
MLNPHKMC_00729 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MLNPHKMC_00730 1.4e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLNPHKMC_00731 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MLNPHKMC_00732 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLNPHKMC_00733 1.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MLNPHKMC_00734 7.3e-107 ytaF P Probably functions as a manganese efflux pump
MLNPHKMC_00735 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLNPHKMC_00736 1.3e-159 ytbE S reductase
MLNPHKMC_00737 2.5e-201 ytbD EGP Major facilitator Superfamily
MLNPHKMC_00738 4.9e-66 ytcD K Transcriptional regulator
MLNPHKMC_00739 3.7e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLNPHKMC_00740 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MLNPHKMC_00741 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MLNPHKMC_00742 2.2e-265 dnaB L Membrane attachment protein
MLNPHKMC_00743 2.5e-172 dnaI L Primosomal protein DnaI
MLNPHKMC_00744 4.6e-109 ytxB S SNARE associated Golgi protein
MLNPHKMC_00745 1.4e-158 ytxC S YtxC-like family
MLNPHKMC_00747 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLNPHKMC_00748 6.2e-148 ysaA S HAD-hyrolase-like
MLNPHKMC_00749 0.0 lytS 2.7.13.3 T Histidine kinase
MLNPHKMC_00750 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
MLNPHKMC_00751 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MLNPHKMC_00752 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MLNPHKMC_00754 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MLNPHKMC_00755 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MLNPHKMC_00756 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MLNPHKMC_00757 7.5e-45 ysdA S Membrane
MLNPHKMC_00758 3.5e-67 ysdB S Sigma-w pathway protein YsdB
MLNPHKMC_00759 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
MLNPHKMC_00760 3.4e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MLNPHKMC_00761 7.8e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MLNPHKMC_00762 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
MLNPHKMC_00763 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MLNPHKMC_00764 5.6e-144 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MLNPHKMC_00765 2.6e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MLNPHKMC_00766 1.8e-253 araN G carbohydrate transport
MLNPHKMC_00767 4.2e-167 araP G carbohydrate transport
MLNPHKMC_00768 3.4e-144 araQ G transport system permease
MLNPHKMC_00769 8.7e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
MLNPHKMC_00770 0.0 cstA T Carbon starvation protein
MLNPHKMC_00771 5.9e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
MLNPHKMC_00772 6.2e-257 glcF C Glycolate oxidase
MLNPHKMC_00773 8.8e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
MLNPHKMC_00774 3e-201 ysfB KT regulator
MLNPHKMC_00775 5.8e-32 sspI S Belongs to the SspI family
MLNPHKMC_00776 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLNPHKMC_00777 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MLNPHKMC_00778 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLNPHKMC_00779 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLNPHKMC_00780 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MLNPHKMC_00781 1.3e-85 cvpA S membrane protein, required for colicin V production
MLNPHKMC_00782 0.0 polX L COG1796 DNA polymerase IV (family X)
MLNPHKMC_00783 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MLNPHKMC_00784 7.3e-68 yshE S membrane
MLNPHKMC_00785 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLNPHKMC_00786 4e-99 fadR K Transcriptional regulator
MLNPHKMC_00787 7e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MLNPHKMC_00788 2.2e-134 etfB C Electron transfer flavoprotein
MLNPHKMC_00789 1.3e-176 etfA C Electron transfer flavoprotein
MLNPHKMC_00791 1.7e-303 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
MLNPHKMC_00792 2e-52 trxA O Belongs to the thioredoxin family
MLNPHKMC_00793 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MLNPHKMC_00794 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MLNPHKMC_00795 1.2e-79 yslB S Protein of unknown function (DUF2507)
MLNPHKMC_00796 2.4e-107 sdhC C succinate dehydrogenase
MLNPHKMC_00797 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MLNPHKMC_00798 1.7e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MLNPHKMC_00799 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
MLNPHKMC_00800 3.3e-30 gerE K Transcriptional regulator
MLNPHKMC_00801 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
MLNPHKMC_00802 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MLNPHKMC_00803 2.9e-196 gerM S COG5401 Spore germination protein
MLNPHKMC_00804 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MLNPHKMC_00805 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MLNPHKMC_00806 1.2e-91 ysnB S Phosphoesterase
MLNPHKMC_00808 3.4e-133 ysnF S protein conserved in bacteria
MLNPHKMC_00809 9.6e-77 ysnE K acetyltransferase
MLNPHKMC_00811 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MLNPHKMC_00812 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
MLNPHKMC_00813 7e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MLNPHKMC_00814 6.4e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MLNPHKMC_00815 1.1e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MLNPHKMC_00816 8.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLNPHKMC_00817 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLNPHKMC_00818 6.2e-185 ysoA H Tetratricopeptide repeat
MLNPHKMC_00819 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MLNPHKMC_00820 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MLNPHKMC_00821 1.7e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MLNPHKMC_00822 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MLNPHKMC_00823 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MLNPHKMC_00824 5.4e-89 ysxD
MLNPHKMC_00825 1.7e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MLNPHKMC_00826 3.6e-146 hemX O cytochrome C
MLNPHKMC_00827 1.6e-171 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MLNPHKMC_00828 7.1e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MLNPHKMC_00829 2.4e-181 hemB 4.2.1.24 H Belongs to the ALAD family
MLNPHKMC_00830 2.8e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MLNPHKMC_00831 3.5e-188 spoVID M stage VI sporulation protein D
MLNPHKMC_00832 7.8e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MLNPHKMC_00833 1.6e-25
MLNPHKMC_00834 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MLNPHKMC_00835 6.2e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MLNPHKMC_00836 1.4e-125 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MLNPHKMC_00837 2.4e-165 spoIIB S Sporulation related domain
MLNPHKMC_00838 2.8e-102 maf D septum formation protein Maf
MLNPHKMC_00839 6.5e-125 radC E Belongs to the UPF0758 family
MLNPHKMC_00840 1.8e-184 mreB D Rod shape-determining protein MreB
MLNPHKMC_00841 2.8e-157 mreC M Involved in formation and maintenance of cell shape
MLNPHKMC_00842 5.4e-84 mreD M shape-determining protein
MLNPHKMC_00843 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MLNPHKMC_00844 2.5e-144 minD D Belongs to the ParA family
MLNPHKMC_00845 8.5e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MLNPHKMC_00846 9.2e-161 spoIVFB S Stage IV sporulation protein
MLNPHKMC_00847 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MLNPHKMC_00848 4.1e-56 ysxB J ribosomal protein
MLNPHKMC_00849 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MLNPHKMC_00850 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MLNPHKMC_00851 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MLNPHKMC_00852 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
MLNPHKMC_00853 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
MLNPHKMC_00854 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
MLNPHKMC_00855 5.9e-227 nifS 2.8.1.7 E Cysteine desulfurase
MLNPHKMC_00856 3.4e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MLNPHKMC_00857 2.3e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MLNPHKMC_00858 1.2e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MLNPHKMC_00859 8.3e-157 safA M spore coat assembly protein SafA
MLNPHKMC_00860 1.7e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLNPHKMC_00861 5.5e-127 yebC K transcriptional regulatory protein
MLNPHKMC_00862 2.6e-261 alsT E Sodium alanine symporter
MLNPHKMC_00863 4e-51 S Family of unknown function (DUF5412)
MLNPHKMC_00865 1.9e-118 yrzF T serine threonine protein kinase
MLNPHKMC_00866 3.7e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MLNPHKMC_00867 4.5e-252 csbX EGP Major facilitator Superfamily
MLNPHKMC_00868 4.8e-93 bofC S BofC C-terminal domain
MLNPHKMC_00869 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MLNPHKMC_00870 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MLNPHKMC_00871 2.2e-17 yrzS S Protein of unknown function (DUF2905)
MLNPHKMC_00872 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MLNPHKMC_00873 1.2e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MLNPHKMC_00874 1.1e-38 yajC U Preprotein translocase subunit YajC
MLNPHKMC_00875 2.2e-73 yrzE S Protein of unknown function (DUF3792)
MLNPHKMC_00876 1.7e-111 yrbG S membrane
MLNPHKMC_00877 1.2e-267 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLNPHKMC_00878 1.6e-48 yrzD S Post-transcriptional regulator
MLNPHKMC_00879 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MLNPHKMC_00880 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
MLNPHKMC_00881 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
MLNPHKMC_00882 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MLNPHKMC_00883 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MLNPHKMC_00884 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MLNPHKMC_00885 1.4e-69 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MLNPHKMC_00886 1.1e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
MLNPHKMC_00888 1.4e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
MLNPHKMC_00889 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MLNPHKMC_00890 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MLNPHKMC_00891 9.7e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MLNPHKMC_00892 1.2e-70 cymR K Transcriptional regulator
MLNPHKMC_00893 2.2e-210 iscS 2.8.1.7 E Cysteine desulfurase
MLNPHKMC_00894 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MLNPHKMC_00895 1.4e-15 S COG0457 FOG TPR repeat
MLNPHKMC_00896 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MLNPHKMC_00897 1.2e-82 yrrD S protein conserved in bacteria
MLNPHKMC_00898 9.8e-31 yrzR
MLNPHKMC_00899 8e-08 S Protein of unknown function (DUF3918)
MLNPHKMC_00900 7.6e-107 glnP P ABC transporter
MLNPHKMC_00901 1.8e-108 gluC P ABC transporter
MLNPHKMC_00902 4.1e-142 glnH ET Belongs to the bacterial solute-binding protein 3 family
MLNPHKMC_00903 1.9e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLNPHKMC_00904 7.8e-170 yrrI S AI-2E family transporter
MLNPHKMC_00905 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MLNPHKMC_00906 1.7e-41 yrzL S Belongs to the UPF0297 family
MLNPHKMC_00907 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MLNPHKMC_00908 1.2e-45 yrzB S Belongs to the UPF0473 family
MLNPHKMC_00909 4.8e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLNPHKMC_00910 1.7e-119 yrrM 2.1.1.104 S O-methyltransferase
MLNPHKMC_00911 4.3e-172 yegQ O Peptidase U32
MLNPHKMC_00912 2.7e-246 yegQ O COG0826 Collagenase and related proteases
MLNPHKMC_00913 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MLNPHKMC_00914 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLNPHKMC_00915 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
MLNPHKMC_00916 4.2e-63 yrrS S Protein of unknown function (DUF1510)
MLNPHKMC_00917 1e-25 yrzA S Protein of unknown function (DUF2536)
MLNPHKMC_00918 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MLNPHKMC_00919 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MLNPHKMC_00920 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MLNPHKMC_00921 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MLNPHKMC_00922 4.6e-35 yrhC S YrhC-like protein
MLNPHKMC_00923 2.4e-78 yrhD S Protein of unknown function (DUF1641)
MLNPHKMC_00924 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MLNPHKMC_00925 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
MLNPHKMC_00926 6.7e-142 focA P Formate nitrite
MLNPHKMC_00929 2.3e-93 yrhH Q methyltransferase
MLNPHKMC_00930 1.8e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
MLNPHKMC_00931 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MLNPHKMC_00932 1.2e-43 yrhK S YrhK-like protein
MLNPHKMC_00933 0.0 yrhL I Acyltransferase family
MLNPHKMC_00934 6.1e-149 rsiV S Protein of unknown function (DUF3298)
MLNPHKMC_00935 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MLNPHKMC_00936 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
MLNPHKMC_00937 3.6e-106 yrhP E LysE type translocator
MLNPHKMC_00938 3.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MLNPHKMC_00939 0.0 levR K PTS system fructose IIA component
MLNPHKMC_00940 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
MLNPHKMC_00941 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
MLNPHKMC_00942 4.4e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MLNPHKMC_00943 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MLNPHKMC_00944 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MLNPHKMC_00945 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
MLNPHKMC_00946 2.5e-197 adhA 1.1.1.1 C alcohol dehydrogenase
MLNPHKMC_00947 4e-24 yphJ 4.1.1.44 S peroxiredoxin activity
MLNPHKMC_00948 4.3e-47 yraB K helix_turn_helix, mercury resistance
MLNPHKMC_00949 1.1e-49 yraD M Spore coat protein
MLNPHKMC_00950 1.7e-25 yraE
MLNPHKMC_00951 1.1e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLNPHKMC_00952 6.4e-63 yraF M Spore coat protein
MLNPHKMC_00953 5.3e-37 yraG
MLNPHKMC_00954 1.3e-66 E Glyoxalase-like domain
MLNPHKMC_00955 2.4e-61 T sh3 domain protein
MLNPHKMC_00956 4.9e-60 T sh3 domain protein
MLNPHKMC_00957 9.9e-149 S Alpha beta hydrolase
MLNPHKMC_00958 3.8e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLNPHKMC_00959 4e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MLNPHKMC_00960 1.1e-186 yrpG C Aldo/keto reductase family
MLNPHKMC_00961 2.7e-94 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
MLNPHKMC_00962 6.6e-115 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MLNPHKMC_00963 5.1e-65 napB K MarR family transcriptional regulator
MLNPHKMC_00964 1.4e-214 yfjF U Belongs to the major facilitator superfamily
MLNPHKMC_00966 1.8e-137 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
MLNPHKMC_00967 7.7e-153 2.2.1.1 G Transketolase, pyrimidine binding domain
MLNPHKMC_00968 1.1e-112 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLNPHKMC_00969 3e-211 rbtT P Major Facilitator Superfamily
MLNPHKMC_00971 2.5e-100 K helix_turn_helix gluconate operon transcriptional repressor
MLNPHKMC_00972 2.5e-124 yrpD S Domain of unknown function, YrpD
MLNPHKMC_00973 5.1e-142 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MLNPHKMC_00974 7.3e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MLNPHKMC_00975 2.2e-159 aadK G Streptomycin adenylyltransferase
MLNPHKMC_00976 6.4e-90 yrdA S DinB family
MLNPHKMC_00977 1.5e-54 S Protein of unknown function (DUF2568)
MLNPHKMC_00978 1e-99 yrdC 3.5.1.19 Q Isochorismatase family
MLNPHKMC_00979 7.3e-228 cypA C Cytochrome P450
MLNPHKMC_00980 2.6e-40 yrdF K ribonuclease inhibitor
MLNPHKMC_00981 5.3e-78 bkdR K helix_turn_helix ASNC type
MLNPHKMC_00982 2.8e-137 azlC E AzlC protein
MLNPHKMC_00983 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
MLNPHKMC_00984 9.5e-226 brnQ E Component of the transport system for branched-chain amino acids
MLNPHKMC_00985 3e-17 yodA S tautomerase
MLNPHKMC_00986 7.7e-153 czcD P COG1230 Co Zn Cd efflux system component
MLNPHKMC_00987 3.3e-197 trkA P Oxidoreductase
MLNPHKMC_00988 1.5e-158 yrdQ K Transcriptional regulator
MLNPHKMC_00989 2.1e-169 yrdR EG EamA-like transporter family
MLNPHKMC_00990 8.7e-16 S YrzO-like protein
MLNPHKMC_00991 6.7e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MLNPHKMC_00992 9.1e-83 bltD 2.3.1.57 K FR47-like protein
MLNPHKMC_00993 1.3e-210 blt EGP Major facilitator Superfamily
MLNPHKMC_00994 3.1e-150 bltR K helix_turn_helix, mercury resistance
MLNPHKMC_00995 1e-104 yrkC G Cupin domain
MLNPHKMC_00996 8.6e-21
MLNPHKMC_00997 7.8e-39 yrkD S protein conserved in bacteria
MLNPHKMC_00998 2.8e-82 yrkE O DsrE/DsrF/DrsH-like family
MLNPHKMC_00999 1.9e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
MLNPHKMC_01000 1.7e-207 yrkH P Rhodanese Homology Domain
MLNPHKMC_01001 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
MLNPHKMC_01002 2.6e-114 yrkJ S membrane transporter protein
MLNPHKMC_01003 1.7e-79 S Protein of unknown function with HXXEE motif
MLNPHKMC_01004 1.5e-97 ywrO S Flavodoxin-like fold
MLNPHKMC_01005 7.6e-100 yrkN K Acetyltransferase (GNAT) family
MLNPHKMC_01006 1.4e-223 yrkO P Protein of unknown function (DUF418)
MLNPHKMC_01007 4.1e-127 T Transcriptional regulator
MLNPHKMC_01008 2.9e-235 yrkQ T Histidine kinase
MLNPHKMC_01009 2e-68 psiE S Protein PsiE homolog
MLNPHKMC_01010 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLNPHKMC_01011 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
MLNPHKMC_01012 6.3e-131 yqeB
MLNPHKMC_01013 6.1e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MLNPHKMC_01014 9.7e-104 yqeD S SNARE associated Golgi protein
MLNPHKMC_01015 8.9e-136 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLNPHKMC_01016 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
MLNPHKMC_01018 5.3e-95 yqeG S hydrolase of the HAD superfamily
MLNPHKMC_01019 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MLNPHKMC_01020 6.6e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLNPHKMC_01021 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MLNPHKMC_01022 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MLNPHKMC_01023 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MLNPHKMC_01024 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MLNPHKMC_01025 1.1e-138 yqeM Q Methyltransferase
MLNPHKMC_01026 5.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLNPHKMC_01027 4.3e-96 wza L COG1555 DNA uptake protein and related DNA-binding proteins
MLNPHKMC_01028 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
MLNPHKMC_01029 0.0 comEC S Competence protein ComEC
MLNPHKMC_01030 4.1e-15 S YqzM-like protein
MLNPHKMC_01031 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
MLNPHKMC_01032 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
MLNPHKMC_01033 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MLNPHKMC_01034 1.5e-222 spoIIP M stage II sporulation protein P
MLNPHKMC_01035 3e-51 yqxA S Protein of unknown function (DUF3679)
MLNPHKMC_01036 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MLNPHKMC_01037 1.9e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
MLNPHKMC_01038 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MLNPHKMC_01039 6.1e-73 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MLNPHKMC_01040 0.0 dnaK O Heat shock 70 kDa protein
MLNPHKMC_01041 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MLNPHKMC_01042 4.6e-174 prmA J Methylates ribosomal protein L11
MLNPHKMC_01043 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MLNPHKMC_01044 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MLNPHKMC_01045 4.1e-157 yqeW P COG1283 Na phosphate symporter
MLNPHKMC_01046 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MLNPHKMC_01047 2.5e-61 yqeY S Yqey-like protein
MLNPHKMC_01048 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MLNPHKMC_01049 4.3e-122 yqfA S UPF0365 protein
MLNPHKMC_01050 3.3e-23 yqfB
MLNPHKMC_01051 2.7e-45 yqfC S sporulation protein YqfC
MLNPHKMC_01052 5.6e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MLNPHKMC_01053 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
MLNPHKMC_01055 0.0 yqfF S membrane-associated HD superfamily hydrolase
MLNPHKMC_01056 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MLNPHKMC_01057 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MLNPHKMC_01058 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MLNPHKMC_01059 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MLNPHKMC_01060 8.4e-19 S YqzL-like protein
MLNPHKMC_01061 1.4e-144 recO L Involved in DNA repair and RecF pathway recombination
MLNPHKMC_01062 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MLNPHKMC_01063 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MLNPHKMC_01064 4.5e-112 ccpN K CBS domain
MLNPHKMC_01065 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MLNPHKMC_01066 4.5e-88 yaiI S Belongs to the UPF0178 family
MLNPHKMC_01067 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MLNPHKMC_01068 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MLNPHKMC_01069 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
MLNPHKMC_01070 2.8e-114 trmK 2.1.1.217 S SAM-dependent methyltransferase
MLNPHKMC_01071 5.3e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MLNPHKMC_01072 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MLNPHKMC_01074 6.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MLNPHKMC_01075 1.2e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MLNPHKMC_01076 2.1e-36 yqfT S Protein of unknown function (DUF2624)
MLNPHKMC_01077 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MLNPHKMC_01078 2.1e-76 zur P Belongs to the Fur family
MLNPHKMC_01079 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MLNPHKMC_01080 4.3e-62 yqfX S membrane
MLNPHKMC_01081 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MLNPHKMC_01082 5.8e-46 yqfZ M LysM domain
MLNPHKMC_01083 1.1e-130 yqgB S Protein of unknown function (DUF1189)
MLNPHKMC_01084 4e-73 yqgC S protein conserved in bacteria
MLNPHKMC_01085 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MLNPHKMC_01086 2.5e-231 yqgE EGP Major facilitator superfamily
MLNPHKMC_01087 0.0 pbpA 3.4.16.4 M penicillin-binding protein
MLNPHKMC_01088 2.9e-149 pstS P Phosphate
MLNPHKMC_01089 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
MLNPHKMC_01090 4.4e-158 pstA P Phosphate transport system permease
MLNPHKMC_01091 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLNPHKMC_01092 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLNPHKMC_01093 7.3e-72 yqzC S YceG-like family
MLNPHKMC_01094 9.2e-51 yqzD
MLNPHKMC_01096 1.3e-193 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
MLNPHKMC_01097 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MLNPHKMC_01098 3.9e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MLNPHKMC_01099 2.5e-09 yqgO
MLNPHKMC_01100 8.9e-236 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MLNPHKMC_01101 4.3e-33 yqgQ S Protein conserved in bacteria
MLNPHKMC_01102 4.4e-180 glcK 2.7.1.2 G Glucokinase
MLNPHKMC_01103 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLNPHKMC_01104 1.8e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
MLNPHKMC_01105 3e-198 yqgU
MLNPHKMC_01106 6.9e-50 yqgV S Thiamine-binding protein
MLNPHKMC_01107 8.9e-23 yqgW S Protein of unknown function (DUF2759)
MLNPHKMC_01108 1.2e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MLNPHKMC_01109 1.8e-37 yqgY S Protein of unknown function (DUF2626)
MLNPHKMC_01110 2.3e-63 yqgZ 1.20.4.1 P Belongs to the ArsC family
MLNPHKMC_01112 2.7e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLNPHKMC_01113 9.8e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MLNPHKMC_01114 7.2e-175 corA P Mg2 transporter protein
MLNPHKMC_01117 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MLNPHKMC_01118 1.1e-173 comGB NU COG1459 Type II secretory pathway, component PulF
MLNPHKMC_01119 1.4e-47 comGC U Required for transformation and DNA binding
MLNPHKMC_01120 9.5e-66 gspH NU protein transport across the cell outer membrane
MLNPHKMC_01121 3.1e-59 comGE
MLNPHKMC_01122 4.1e-46 comGF U Putative Competence protein ComGF
MLNPHKMC_01123 1.2e-43 S ComG operon protein 7
MLNPHKMC_01124 5.2e-26 yqzE S YqzE-like protein
MLNPHKMC_01125 2.6e-52 yqzG S Protein of unknown function (DUF3889)
MLNPHKMC_01126 3.2e-109 yqxM
MLNPHKMC_01127 6.7e-59 sipW 3.4.21.89 U Signal peptidase
MLNPHKMC_01128 8.6e-142 tasA S Cell division protein FtsN
MLNPHKMC_01129 1e-54 sinR K transcriptional
MLNPHKMC_01130 3.6e-24 sinI S Anti-repressor SinI
MLNPHKMC_01131 1e-150 yqhG S Bacterial protein YqhG of unknown function
MLNPHKMC_01132 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLNPHKMC_01133 3.7e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MLNPHKMC_01134 9.3e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLNPHKMC_01135 1e-284 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLNPHKMC_01136 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
MLNPHKMC_01137 7.5e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MLNPHKMC_01138 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MLNPHKMC_01139 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
MLNPHKMC_01140 2.2e-61 yqhP
MLNPHKMC_01141 1.4e-173 yqhQ S Protein of unknown function (DUF1385)
MLNPHKMC_01142 2.3e-93 yqhR S Conserved membrane protein YqhR
MLNPHKMC_01143 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MLNPHKMC_01144 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MLNPHKMC_01145 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MLNPHKMC_01146 7.9e-37 yqhV S Protein of unknown function (DUF2619)
MLNPHKMC_01147 1.5e-169 spoIIIAA S stage III sporulation protein AA
MLNPHKMC_01148 4.1e-84 spoIIIAB S Stage III sporulation protein
MLNPHKMC_01149 7.6e-29 spoIIIAC S stage III sporulation protein AC
MLNPHKMC_01150 2.3e-58 spoIIIAD S Stage III sporulation protein AD
MLNPHKMC_01151 1.3e-197 spoIIIAE S stage III sporulation protein AE
MLNPHKMC_01152 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MLNPHKMC_01153 2.2e-109 spoIIIAG S stage III sporulation protein AG
MLNPHKMC_01154 1.1e-89 spoIIIAH S SpoIIIAH-like protein
MLNPHKMC_01155 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MLNPHKMC_01156 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MLNPHKMC_01157 2.1e-67 yqhY S protein conserved in bacteria
MLNPHKMC_01158 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLNPHKMC_01159 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLNPHKMC_01160 8.4e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLNPHKMC_01161 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLNPHKMC_01162 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MLNPHKMC_01163 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MLNPHKMC_01164 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MLNPHKMC_01165 5.6e-77 argR K Regulates arginine biosynthesis genes
MLNPHKMC_01166 1.1e-306 recN L May be involved in recombinational repair of damaged DNA
MLNPHKMC_01167 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
MLNPHKMC_01168 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MLNPHKMC_01170 1.4e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MLNPHKMC_01171 5.9e-27
MLNPHKMC_01172 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
MLNPHKMC_01173 1.4e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MLNPHKMC_01174 2.2e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
MLNPHKMC_01175 3.7e-154 hbdA 1.1.1.157 I Dehydrogenase
MLNPHKMC_01176 2e-211 mmgC I acyl-CoA dehydrogenase
MLNPHKMC_01177 1.3e-204 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MLNPHKMC_01178 1.7e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MLNPHKMC_01179 1.3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MLNPHKMC_01180 4e-34 yqzF S Protein of unknown function (DUF2627)
MLNPHKMC_01181 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
MLNPHKMC_01182 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
MLNPHKMC_01183 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MLNPHKMC_01184 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
MLNPHKMC_01185 1.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLNPHKMC_01186 4.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLNPHKMC_01187 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLNPHKMC_01188 3.2e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLNPHKMC_01189 2.6e-152 bmrR K helix_turn_helix, mercury resistance
MLNPHKMC_01190 7.9e-208 norA EGP Major facilitator Superfamily
MLNPHKMC_01191 3.1e-164 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLNPHKMC_01192 9.3e-77 yqiW S Belongs to the UPF0403 family
MLNPHKMC_01193 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
MLNPHKMC_01194 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
MLNPHKMC_01195 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLNPHKMC_01196 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
MLNPHKMC_01197 1.8e-98 yqjB S protein conserved in bacteria
MLNPHKMC_01199 1.9e-71 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
MLNPHKMC_01200 8.6e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLNPHKMC_01201 1.4e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MLNPHKMC_01202 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
MLNPHKMC_01203 1.5e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLNPHKMC_01204 6.2e-24 yqzJ
MLNPHKMC_01205 1.2e-233 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLNPHKMC_01206 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLNPHKMC_01207 3.3e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MLNPHKMC_01208 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MLNPHKMC_01209 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MLNPHKMC_01210 1.8e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLNPHKMC_01211 1.8e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MLNPHKMC_01212 0.0 rocB E arginine degradation protein
MLNPHKMC_01213 3.3e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLNPHKMC_01214 4.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
MLNPHKMC_01215 2.9e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MLNPHKMC_01216 5.4e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MLNPHKMC_01217 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
MLNPHKMC_01218 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLNPHKMC_01220 5.2e-226 yqjV G Major Facilitator Superfamily
MLNPHKMC_01222 9.2e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLNPHKMC_01223 2.2e-49 S YolD-like protein
MLNPHKMC_01224 5.3e-86 yqjY K acetyltransferase
MLNPHKMC_01225 1.5e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
MLNPHKMC_01226 1.4e-167 yqkA K GrpB protein
MLNPHKMC_01227 3.7e-54 yqkB S Belongs to the HesB IscA family
MLNPHKMC_01228 9.4e-39 yqkC S Protein of unknown function (DUF2552)
MLNPHKMC_01229 1.1e-169 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MLNPHKMC_01230 3.1e-12 yqkE S Protein of unknown function (DUF3886)
MLNPHKMC_01231 9.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MLNPHKMC_01233 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MLNPHKMC_01234 8.1e-221 yqxK 3.6.4.12 L DNA helicase
MLNPHKMC_01235 4.5e-58 ansR K Transcriptional regulator
MLNPHKMC_01236 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
MLNPHKMC_01237 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MLNPHKMC_01238 9.1e-235 mleN C Na H antiporter
MLNPHKMC_01239 1.6e-241 mleA 1.1.1.38 C malic enzyme
MLNPHKMC_01240 2.1e-29 yqkK
MLNPHKMC_01241 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MLNPHKMC_01242 2.4e-80 fur P Belongs to the Fur family
MLNPHKMC_01243 3.7e-37 S Protein of unknown function (DUF4227)
MLNPHKMC_01244 8.2e-165 xerD L recombinase XerD
MLNPHKMC_01245 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MLNPHKMC_01246 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MLNPHKMC_01247 5.3e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MLNPHKMC_01248 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MLNPHKMC_01249 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MLNPHKMC_01250 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLNPHKMC_01251 9.6e-112 spoVAA S Stage V sporulation protein AA
MLNPHKMC_01252 1e-67 spoVAB S Stage V sporulation protein AB
MLNPHKMC_01253 2.3e-78 spoVAC S stage V sporulation protein AC
MLNPHKMC_01254 9e-192 spoVAD I Stage V sporulation protein AD
MLNPHKMC_01255 2.2e-57 spoVAEB S stage V sporulation protein
MLNPHKMC_01256 1.4e-110 spoVAEA S stage V sporulation protein
MLNPHKMC_01257 1.4e-273 spoVAF EG Stage V sporulation protein AF
MLNPHKMC_01258 2.2e-254 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MLNPHKMC_01259 8.1e-149 ypuA S Secreted protein
MLNPHKMC_01260 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MLNPHKMC_01262 9.8e-14 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
MLNPHKMC_01263 4e-93 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLNPHKMC_01264 7.8e-55 ypuD
MLNPHKMC_01265 8.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MLNPHKMC_01266 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
MLNPHKMC_01267 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MLNPHKMC_01268 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MLNPHKMC_01269 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLNPHKMC_01270 9.4e-92 ypuF S Domain of unknown function (DUF309)
MLNPHKMC_01271 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MLNPHKMC_01272 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MLNPHKMC_01273 7.6e-97 ypuI S Protein of unknown function (DUF3907)
MLNPHKMC_01274 4e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MLNPHKMC_01275 8.6e-102 spmA S Spore maturation protein
MLNPHKMC_01276 4.2e-87 spmB S Spore maturation protein
MLNPHKMC_01277 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MLNPHKMC_01278 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MLNPHKMC_01279 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MLNPHKMC_01280 8.8e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MLNPHKMC_01281 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLNPHKMC_01282 0.0 resE 2.7.13.3 T Histidine kinase
MLNPHKMC_01283 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
MLNPHKMC_01284 3.6e-186 rsiX
MLNPHKMC_01285 2.5e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MLNPHKMC_01286 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLNPHKMC_01287 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MLNPHKMC_01288 4.7e-41 fer C Ferredoxin
MLNPHKMC_01289 1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
MLNPHKMC_01290 2.5e-283 recQ 3.6.4.12 L DNA helicase
MLNPHKMC_01291 1.7e-97 ypbD S metal-dependent membrane protease
MLNPHKMC_01292 2.2e-78 ypbE M Lysin motif
MLNPHKMC_01293 2.8e-81 ypbF S Protein of unknown function (DUF2663)
MLNPHKMC_01294 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
MLNPHKMC_01295 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLNPHKMC_01296 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MLNPHKMC_01297 8.7e-176 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MLNPHKMC_01298 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
MLNPHKMC_01299 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MLNPHKMC_01300 5.5e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MLNPHKMC_01301 5e-111 ypfA M Flagellar protein YcgR
MLNPHKMC_01302 2.4e-23 S Family of unknown function (DUF5359)
MLNPHKMC_01303 8.9e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MLNPHKMC_01304 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
MLNPHKMC_01305 1.2e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MLNPHKMC_01306 1e-07 S YpzI-like protein
MLNPHKMC_01307 5.1e-102 yphA
MLNPHKMC_01308 2.5e-161 seaA S YIEGIA protein
MLNPHKMC_01309 2.3e-27 ypzH
MLNPHKMC_01310 1.5e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MLNPHKMC_01311 3.6e-180 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MLNPHKMC_01312 2e-18 yphE S Protein of unknown function (DUF2768)
MLNPHKMC_01313 6e-137 yphF
MLNPHKMC_01314 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MLNPHKMC_01315 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLNPHKMC_01316 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
MLNPHKMC_01317 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MLNPHKMC_01318 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MLNPHKMC_01319 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MLNPHKMC_01320 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MLNPHKMC_01321 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MLNPHKMC_01322 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MLNPHKMC_01323 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MLNPHKMC_01324 4.9e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MLNPHKMC_01325 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MLNPHKMC_01326 4.9e-290 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLNPHKMC_01327 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MLNPHKMC_01328 8.9e-112 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MLNPHKMC_01329 1.8e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MLNPHKMC_01330 2.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MLNPHKMC_01331 1e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MLNPHKMC_01332 7.8e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MLNPHKMC_01333 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MLNPHKMC_01334 1.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MLNPHKMC_01335 2.7e-233 S COG0457 FOG TPR repeat
MLNPHKMC_01336 2.8e-99 ypiB S Belongs to the UPF0302 family
MLNPHKMC_01337 4.2e-77 ypiF S Protein of unknown function (DUF2487)
MLNPHKMC_01338 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
MLNPHKMC_01339 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
MLNPHKMC_01340 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MLNPHKMC_01341 4.4e-98 ypjA S membrane
MLNPHKMC_01342 1e-142 ypjB S sporulation protein
MLNPHKMC_01343 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MLNPHKMC_01344 2.6e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MLNPHKMC_01345 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MLNPHKMC_01346 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MLNPHKMC_01347 4.5e-129 bshB1 S proteins, LmbE homologs
MLNPHKMC_01348 5.3e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MLNPHKMC_01349 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MLNPHKMC_01350 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MLNPHKMC_01351 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MLNPHKMC_01352 4.4e-155 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MLNPHKMC_01353 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MLNPHKMC_01354 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MLNPHKMC_01355 1.9e-22 ypmA S Protein of unknown function (DUF4264)
MLNPHKMC_01356 1.1e-78 ypmB S protein conserved in bacteria
MLNPHKMC_01357 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MLNPHKMC_01358 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
MLNPHKMC_01359 5.7e-129 dnaD L DNA replication protein DnaD
MLNPHKMC_01360 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MLNPHKMC_01361 4.7e-93 ypoC
MLNPHKMC_01362 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
MLNPHKMC_01363 2.7e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLNPHKMC_01364 7.7e-185 yppC S Protein of unknown function (DUF2515)
MLNPHKMC_01367 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
MLNPHKMC_01369 1.2e-48 yppG S YppG-like protein
MLNPHKMC_01370 1.2e-70 hspX O Belongs to the small heat shock protein (HSP20) family
MLNPHKMC_01371 3.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MLNPHKMC_01372 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MLNPHKMC_01373 1.6e-235 yprB L RNase_H superfamily
MLNPHKMC_01374 2.8e-91 ypsA S Belongs to the UPF0398 family
MLNPHKMC_01375 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MLNPHKMC_01376 1.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MLNPHKMC_01378 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
MLNPHKMC_01379 1.9e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLNPHKMC_01380 1.4e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MLNPHKMC_01381 1.5e-186 ptxS K transcriptional
MLNPHKMC_01382 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MLNPHKMC_01383 5e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MLNPHKMC_01384 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MLNPHKMC_01385 6.2e-290 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MLNPHKMC_01386 2.8e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MLNPHKMC_01387 1.6e-225 pbuX F xanthine
MLNPHKMC_01388 4.8e-207 bcsA Q Naringenin-chalcone synthase
MLNPHKMC_01389 5.1e-87 ypbQ S protein conserved in bacteria
MLNPHKMC_01390 0.0 ypbR S Dynamin family
MLNPHKMC_01391 2.2e-38 ypbS S Protein of unknown function (DUF2533)
MLNPHKMC_01392 2e-07
MLNPHKMC_01393 4.4e-166 polA 2.7.7.7 L 5'3' exonuclease
MLNPHKMC_01395 2.7e-67 rnhA 3.1.26.4 L Ribonuclease
MLNPHKMC_01396 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MLNPHKMC_01397 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
MLNPHKMC_01398 3e-29 ypeQ S Zinc-finger
MLNPHKMC_01399 8.1e-31 S Protein of unknown function (DUF2564)
MLNPHKMC_01400 3.8e-16 degR
MLNPHKMC_01401 1e-30 cspD K Cold-shock protein
MLNPHKMC_01402 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MLNPHKMC_01403 1.4e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MLNPHKMC_01404 2.6e-88 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MLNPHKMC_01405 3.4e-109 ypgQ S phosphohydrolase
MLNPHKMC_01406 1.7e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
MLNPHKMC_01407 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MLNPHKMC_01408 1.7e-75 yphP S Belongs to the UPF0403 family
MLNPHKMC_01409 9.1e-144 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
MLNPHKMC_01410 2.3e-113 ypjP S YpjP-like protein
MLNPHKMC_01411 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MLNPHKMC_01412 4.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MLNPHKMC_01413 5.8e-109 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLNPHKMC_01414 4.2e-110 hlyIII S protein, Hemolysin III
MLNPHKMC_01415 1.5e-183 pspF K Transcriptional regulator
MLNPHKMC_01416 2.4e-242 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MLNPHKMC_01417 3.4e-39 ypmP S Protein of unknown function (DUF2535)
MLNPHKMC_01418 2.7e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MLNPHKMC_01419 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
MLNPHKMC_01420 4.2e-98 ypmS S protein conserved in bacteria
MLNPHKMC_01421 1.6e-28 ypmT S Uncharacterized ympT
MLNPHKMC_01422 5.8e-223 mepA V MATE efflux family protein
MLNPHKMC_01423 1.6e-70 ypoP K transcriptional
MLNPHKMC_01424 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLNPHKMC_01425 2.4e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MLNPHKMC_01426 3.2e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
MLNPHKMC_01427 1.8e-237 yokA L Recombinase
MLNPHKMC_01429 5.2e-68 S SMI1 / KNR4 family
MLNPHKMC_01430 2.6e-54 S DNase/tRNase domain of colicin-like bacteriocin
MLNPHKMC_01431 3.2e-108 yokF 3.1.31.1 L RNA catabolic process
MLNPHKMC_01432 4.1e-203
MLNPHKMC_01433 3.3e-78 yokH G SMI1 / KNR4 family
MLNPHKMC_01434 5e-214 UW nuclease activity
MLNPHKMC_01435 7.6e-92 yokK S SMI1 / KNR4 family
MLNPHKMC_01436 2.3e-09 S Domain of unknown function (DUF4879)
MLNPHKMC_01438 1.5e-39
MLNPHKMC_01439 1e-51 S YolD-like protein
MLNPHKMC_01440 5.1e-237 S impB/mucB/samB family C-terminal domain
MLNPHKMC_01443 0.0 V Peptidase C39 family
MLNPHKMC_01444 1.2e-70 CO cell redox homeostasis
MLNPHKMC_01445 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLNPHKMC_01446 3.4e-74 O protein disulfide oxidoreductase activity
MLNPHKMC_01447 5.5e-40 S SPP1 phage holin
MLNPHKMC_01448 4.4e-32 bhlA S BhlA holin family
MLNPHKMC_01449 1.6e-186 3.5.1.28 M Ami_2
MLNPHKMC_01450 1.4e-163
MLNPHKMC_01451 2.2e-09 S Phage uncharacterised protein (Phage_XkdX)
MLNPHKMC_01453 4.1e-54
MLNPHKMC_01454 9.8e-104
MLNPHKMC_01455 7.3e-294 S Pfam Transposase IS66
MLNPHKMC_01456 6.1e-81 S Phage tail protein
MLNPHKMC_01457 6.3e-305 S peptidoglycan catabolic process
MLNPHKMC_01458 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLNPHKMC_01459 1.4e-34
MLNPHKMC_01460 4.1e-62
MLNPHKMC_01462 1.2e-122 xerH L Belongs to the 'phage' integrase family
MLNPHKMC_01463 7.5e-63
MLNPHKMC_01464 1.1e-81
MLNPHKMC_01466 3.3e-47
MLNPHKMC_01467 2.2e-10
MLNPHKMC_01468 4.9e-52
MLNPHKMC_01470 2.3e-89
MLNPHKMC_01471 8.1e-131
MLNPHKMC_01472 1.3e-90
MLNPHKMC_01473 1.4e-121
MLNPHKMC_01475 1.1e-68
MLNPHKMC_01476 1.1e-80
MLNPHKMC_01477 1.6e-185
MLNPHKMC_01478 7.8e-94
MLNPHKMC_01479 3.4e-245
MLNPHKMC_01480 2.7e-277
MLNPHKMC_01481 0.0 gp17a S Terminase-like family
MLNPHKMC_01482 2.6e-174
MLNPHKMC_01485 3.4e-198 S Calcineurin-like phosphoesterase superfamily domain
MLNPHKMC_01487 1.9e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLNPHKMC_01488 5.8e-94
MLNPHKMC_01489 1.6e-14 L GIY-YIG type nucleases (URI domain)
MLNPHKMC_01490 0.0 S RNA-directed RNA polymerase activity
MLNPHKMC_01492 1.8e-53 bldD K domain, Protein
MLNPHKMC_01493 1.5e-16
MLNPHKMC_01495 3.6e-203
MLNPHKMC_01508 1.1e-08 ywlA S Uncharacterised protein family (UPF0715)
MLNPHKMC_01509 6.2e-81 yoaW
MLNPHKMC_01510 1.8e-31 K Cro/C1-type HTH DNA-binding domain
MLNPHKMC_01512 9.7e-12 ywlA S Uncharacterised protein family (UPF0715)
MLNPHKMC_01513 1e-79 K Divergent AAA domain
MLNPHKMC_01518 5.9e-12
MLNPHKMC_01519 2.1e-31
MLNPHKMC_01522 3.9e-39
MLNPHKMC_01523 9.5e-78
MLNPHKMC_01528 1.2e-194 L Belongs to the 'phage' integrase family
MLNPHKMC_01529 5.6e-253 S DNA-sulfur modification-associated
MLNPHKMC_01530 1e-176
MLNPHKMC_01531 1.1e-33 K Transcriptional regulator
MLNPHKMC_01536 1.7e-10 FG Mazg nucleotide pyrophosphohydrolase
MLNPHKMC_01542 1.2e-63 yoqH M LysM domain
MLNPHKMC_01545 1.9e-97 S Protein of unknown function (DUF1273)
MLNPHKMC_01550 2.5e-82 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
MLNPHKMC_01553 8.9e-150 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
MLNPHKMC_01554 1.5e-82 yoqW S Belongs to the SOS response-associated peptidase family
MLNPHKMC_01561 1.6e-155
MLNPHKMC_01562 7.6e-180 L AAA domain
MLNPHKMC_01563 4.5e-85
MLNPHKMC_01564 2.6e-283 3.6.4.12 J DnaB-like helicase C terminal domain
MLNPHKMC_01565 3.9e-220 L DNA primase activity
MLNPHKMC_01566 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MLNPHKMC_01567 0.0 S Bacterial DNA polymerase III alpha subunit
MLNPHKMC_01568 1.6e-110 DR0488 S protein conserved in bacteria
MLNPHKMC_01574 6.6e-79 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
MLNPHKMC_01580 5.6e-13
MLNPHKMC_01592 6.9e-63 S NrdI Flavodoxin like
MLNPHKMC_01593 2.8e-123 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
MLNPHKMC_01594 3.8e-197 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLNPHKMC_01596 6.6e-187 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLNPHKMC_01597 6.1e-38 O Glutaredoxin
MLNPHKMC_01598 1.1e-09
MLNPHKMC_01599 1.1e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MLNPHKMC_01600 2.9e-15 V COG4767 Glycopeptide antibiotics resistance protein
MLNPHKMC_01603 1.1e-38 S Protein of unknown function (DUF1643)
MLNPHKMC_01604 2.2e-159 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLNPHKMC_01605 4.1e-19 folA 1.5.1.3, 2.7.6.3 H Dihydrofolate reductase
MLNPHKMC_01610 1.2e-29 sspB S spore protein
MLNPHKMC_01612 1.8e-134
MLNPHKMC_01615 4.4e-106 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLNPHKMC_01617 6.2e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
MLNPHKMC_01618 1.4e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
MLNPHKMC_01619 1.2e-177 cgeB S Spore maturation protein
MLNPHKMC_01620 3.1e-63 cgeA
MLNPHKMC_01621 3.8e-37 cgeC
MLNPHKMC_01622 2.5e-255 cgeD M maturation of the outermost layer of the spore
MLNPHKMC_01623 5.9e-143 yiiD K acetyltransferase
MLNPHKMC_01625 3.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLNPHKMC_01626 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLNPHKMC_01627 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLNPHKMC_01628 1.2e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
MLNPHKMC_01629 1.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
MLNPHKMC_01630 1.1e-277 kamA 5.4.3.2 E lysine 2,3-aminomutase
MLNPHKMC_01631 2.9e-47 yokU S YokU-like protein, putative antitoxin
MLNPHKMC_01632 1.4e-36 yozE S Belongs to the UPF0346 family
MLNPHKMC_01633 6e-123 yodN
MLNPHKMC_01635 2.8e-24 yozD S YozD-like protein
MLNPHKMC_01636 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
MLNPHKMC_01637 3.6e-54 yodL S YodL-like
MLNPHKMC_01638 5.3e-09
MLNPHKMC_01639 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MLNPHKMC_01640 2.1e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MLNPHKMC_01641 1.5e-23 yodI
MLNPHKMC_01642 2.4e-127 yodH Q Methyltransferase
MLNPHKMC_01643 1.5e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MLNPHKMC_01644 4.3e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLNPHKMC_01645 6.2e-28 S Protein of unknown function (DUF3311)
MLNPHKMC_01646 1.7e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
MLNPHKMC_01647 8.5e-113 mhqD S Carboxylesterase
MLNPHKMC_01648 1.4e-107 yodC C nitroreductase
MLNPHKMC_01649 4.4e-55 yodB K transcriptional
MLNPHKMC_01650 4.7e-64 yodA S tautomerase
MLNPHKMC_01651 2.3e-128 gntP EG COG2610 H gluconate symporter and related permeases
MLNPHKMC_01652 4.4e-59 gntP EG COG2610 H gluconate symporter and related permeases
MLNPHKMC_01653 3.4e-09
MLNPHKMC_01654 8.6e-65 yozR S COG0071 Molecular chaperone (small heat shock protein)
MLNPHKMC_01655 8.6e-162 rarD S -transporter
MLNPHKMC_01656 1.2e-42
MLNPHKMC_01657 2.2e-60 yojF S Protein of unknown function (DUF1806)
MLNPHKMC_01658 3.7e-125 yojG S deacetylase
MLNPHKMC_01659 1.6e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLNPHKMC_01660 4.7e-244 norM V Multidrug efflux pump
MLNPHKMC_01662 2.2e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLNPHKMC_01663 1.5e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
MLNPHKMC_01664 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MLNPHKMC_01665 5e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MLNPHKMC_01666 1.2e-160 yojN S ATPase family associated with various cellular activities (AAA)
MLNPHKMC_01667 0.0 yojO P Von Willebrand factor
MLNPHKMC_01668 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MLNPHKMC_01669 9.4e-191 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MLNPHKMC_01670 1.6e-166 yocS S -transporter
MLNPHKMC_01671 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLNPHKMC_01672 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
MLNPHKMC_01673 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
MLNPHKMC_01674 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MLNPHKMC_01675 2.7e-31 yozC
MLNPHKMC_01676 4.2e-56 yozO S Bacterial PH domain
MLNPHKMC_01677 1.9e-36 yocN
MLNPHKMC_01678 1.1e-40 yozN
MLNPHKMC_01679 2.4e-86 yocM O Belongs to the small heat shock protein (HSP20) family
MLNPHKMC_01680 5.8e-30
MLNPHKMC_01681 8.4e-54 yocL
MLNPHKMC_01682 8.2e-82 dksA T general stress protein
MLNPHKMC_01683 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLNPHKMC_01684 0.0 recQ 3.6.4.12 L DNA helicase
MLNPHKMC_01685 1.7e-111 yocH CBM50 M COG1388 FOG LysM repeat
MLNPHKMC_01686 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLNPHKMC_01687 7.1e-198 desK 2.7.13.3 T Histidine kinase
MLNPHKMC_01688 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MLNPHKMC_01689 9.3e-186 yocD 3.4.17.13 V peptidase S66
MLNPHKMC_01690 6.1e-93 yocC
MLNPHKMC_01691 6.4e-145
MLNPHKMC_01692 1.5e-92 yozB S membrane
MLNPHKMC_01693 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLNPHKMC_01694 1e-51 czrA K transcriptional
MLNPHKMC_01695 1e-93 yobW
MLNPHKMC_01696 2.8e-171 yobV K WYL domain
MLNPHKMC_01697 7.1e-86 yobU K Bacterial transcription activator, effector binding domain
MLNPHKMC_01698 4.7e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
MLNPHKMC_01699 3.6e-97 yobS K Transcriptional regulator
MLNPHKMC_01700 5.3e-141 yobR 2.3.1.1 J FR47-like protein
MLNPHKMC_01701 1.4e-133 yobQ K helix_turn_helix, arabinose operon control protein
MLNPHKMC_01702 1.9e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
MLNPHKMC_01703 2e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
MLNPHKMC_01704 4.1e-101 yokH G SMI1 / KNR4 family
MLNPHKMC_01705 3.1e-304 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLNPHKMC_01706 3.3e-85 S SMI1-KNR4 cell-wall
MLNPHKMC_01707 2.8e-47
MLNPHKMC_01709 6.4e-11 S YolD-like protein
MLNPHKMC_01710 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
MLNPHKMC_01711 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MLNPHKMC_01714 9.1e-167 bla 3.5.2.6 V beta-lactamase
MLNPHKMC_01715 2.8e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MLNPHKMC_01716 1.8e-77 yoaW
MLNPHKMC_01717 1.8e-159 yijE EG EamA-like transporter family
MLNPHKMC_01718 3.3e-158 yoaU K LysR substrate binding domain
MLNPHKMC_01719 1.6e-148 yoaT S Protein of unknown function (DUF817)
MLNPHKMC_01720 6e-30 yozG K Transcriptional regulator
MLNPHKMC_01721 7.3e-75 yoaS S Protein of unknown function (DUF2975)
MLNPHKMC_01722 7.1e-172 yoaR V vancomycin resistance protein
MLNPHKMC_01723 1.1e-84
MLNPHKMC_01725 8.7e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
MLNPHKMC_01728 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
MLNPHKMC_01729 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
MLNPHKMC_01730 2.3e-111 yoaK S Membrane
MLNPHKMC_01731 5e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
MLNPHKMC_01732 4.8e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
MLNPHKMC_01733 1.9e-178 mcpU NT methyl-accepting chemotaxis protein
MLNPHKMC_01734 1.7e-34 S Protein of unknown function (DUF4025)
MLNPHKMC_01735 7e-14
MLNPHKMC_01736 2.2e-07
MLNPHKMC_01737 3.3e-90 purR K Transcriptional regulator
MLNPHKMC_01738 3.2e-151 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
MLNPHKMC_01739 1.6e-205 S Oxidoreductase family, C-terminal alpha/beta domain
MLNPHKMC_01740 1.5e-171 iolT EGP Major facilitator Superfamily
MLNPHKMC_01741 8.7e-32 yoaF
MLNPHKMC_01742 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLNPHKMC_01743 3.4e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLNPHKMC_01744 1.7e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MLNPHKMC_01745 9.9e-233 yoaB EGP Major facilitator Superfamily
MLNPHKMC_01746 6.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
MLNPHKMC_01747 4.8e-139 V AAA domain, putative AbiEii toxin, Type IV TA system
MLNPHKMC_01748 6.4e-94 V ABC-2 family transporter protein
MLNPHKMC_01749 1.4e-125 V ABC-2 family transporter protein
MLNPHKMC_01750 4.1e-95 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLNPHKMC_01751 3.6e-132 yoxB
MLNPHKMC_01752 9.2e-39 yoxC S Bacterial protein of unknown function (DUF948)
MLNPHKMC_01753 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MLNPHKMC_01754 2.5e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MLNPHKMC_01755 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLNPHKMC_01756 1.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLNPHKMC_01757 7.8e-155 gltC K Transcriptional regulator
MLNPHKMC_01758 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MLNPHKMC_01759 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MLNPHKMC_01760 2.6e-183 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MLNPHKMC_01761 5.7e-155 gltR1 K Transcriptional regulator
MLNPHKMC_01762 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MLNPHKMC_01763 3e-34 yoeD G Helix-turn-helix domain
MLNPHKMC_01764 2.2e-96 L Integrase
MLNPHKMC_01766 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
MLNPHKMC_01767 1.9e-245 yoeA V MATE efflux family protein
MLNPHKMC_01768 2.1e-190 yoxA 5.1.3.3 G Aldose 1-epimerase
MLNPHKMC_01769 1.3e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MLNPHKMC_01770 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLNPHKMC_01771 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLNPHKMC_01772 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLNPHKMC_01773 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLNPHKMC_01774 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MLNPHKMC_01775 2.3e-63 yngL S Protein of unknown function (DUF1360)
MLNPHKMC_01776 4.2e-302 yngK T Glycosyl hydrolase-like 10
MLNPHKMC_01777 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MLNPHKMC_01778 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLNPHKMC_01779 4.7e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MLNPHKMC_01780 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MLNPHKMC_01781 7.5e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
MLNPHKMC_01782 2.7e-135 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MLNPHKMC_01783 2.7e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLNPHKMC_01784 1.1e-231 nrnB S phosphohydrolase (DHH superfamily)
MLNPHKMC_01785 5.5e-104 yngC S membrane-associated protein
MLNPHKMC_01786 1.3e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MLNPHKMC_01787 4.5e-79 yngA S membrane
MLNPHKMC_01788 1.7e-295 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
MLNPHKMC_01789 5.3e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
MLNPHKMC_01791 3.9e-292 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
MLNPHKMC_01792 5.3e-251 agcS E Sodium alanine symporter
MLNPHKMC_01793 8.6e-57 ynfC
MLNPHKMC_01794 2.3e-12
MLNPHKMC_01795 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLNPHKMC_01796 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLNPHKMC_01797 6.6e-69 yccU S CoA-binding protein
MLNPHKMC_01798 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MLNPHKMC_01799 4.1e-49 yneR S Belongs to the HesB IscA family
MLNPHKMC_01800 2.2e-53 yneQ
MLNPHKMC_01801 1.2e-73 yneP S Thioesterase-like superfamily
MLNPHKMC_01802 3.9e-35 tlp S Belongs to the Tlp family
MLNPHKMC_01803 3.1e-08 sspN S Small acid-soluble spore protein N family
MLNPHKMC_01805 1e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MLNPHKMC_01806 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MLNPHKMC_01807 2.5e-14 sspO S Belongs to the SspO family
MLNPHKMC_01808 4.3e-18 sspP S Belongs to the SspP family
MLNPHKMC_01809 2.2e-63 hspX O Spore coat protein
MLNPHKMC_01810 4.2e-74 yneK S Protein of unknown function (DUF2621)
MLNPHKMC_01811 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MLNPHKMC_01812 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MLNPHKMC_01813 1.2e-126 ccdA O cytochrome c biogenesis protein
MLNPHKMC_01814 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
MLNPHKMC_01815 1.8e-28 yneF S UPF0154 protein
MLNPHKMC_01816 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
MLNPHKMC_01817 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MLNPHKMC_01818 1.3e-32 ynzC S UPF0291 protein
MLNPHKMC_01819 9.2e-113 yneB L resolvase
MLNPHKMC_01820 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MLNPHKMC_01821 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MLNPHKMC_01822 1.1e-77 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MLNPHKMC_01823 5.8e-74 yndM S Protein of unknown function (DUF2512)
MLNPHKMC_01824 9.9e-135 yndL S Replication protein
MLNPHKMC_01826 7.2e-308 yndJ S YndJ-like protein
MLNPHKMC_01827 2.4e-115 yndH S Domain of unknown function (DUF4166)
MLNPHKMC_01828 1.2e-151 yndG S DoxX-like family
MLNPHKMC_01829 3.3e-217 gerLC S Spore germination protein
MLNPHKMC_01830 1.8e-193 gerAB U Spore germination
MLNPHKMC_01831 3.4e-283 gerAA EG Spore germination protein
MLNPHKMC_01834 7.5e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
MLNPHKMC_01835 1.8e-71
MLNPHKMC_01836 7.9e-25 tatA U protein secretion
MLNPHKMC_01839 3.3e-130 S Domain of unknown function, YrpD
MLNPHKMC_01841 5.4e-32
MLNPHKMC_01842 6.6e-164 S Thymidylate synthase
MLNPHKMC_01844 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MLNPHKMC_01845 1.6e-79 yncE S Protein of unknown function (DUF2691)
MLNPHKMC_01846 1.7e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLNPHKMC_01847 6.1e-255 iolT EGP Major facilitator Superfamily
MLNPHKMC_01848 1.7e-111 yokF 3.1.31.1 L RNA catabolic process
MLNPHKMC_01849 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
MLNPHKMC_01850 4.4e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MLNPHKMC_01851 7.3e-214 xylR GK ROK family
MLNPHKMC_01852 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MLNPHKMC_01853 7.9e-255 xynT G MFS/sugar transport protein
MLNPHKMC_01854 3.5e-82 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
MLNPHKMC_01855 9.9e-120 ynaE S Domain of unknown function (DUF3885)
MLNPHKMC_01856 4.5e-99 ynaD J Acetyltransferase (GNAT) domain
MLNPHKMC_01857 9.5e-19 ynaC
MLNPHKMC_01858 1.2e-89 G SMI1-KNR4 cell-wall
MLNPHKMC_01859 6.4e-38
MLNPHKMC_01860 1.7e-124
MLNPHKMC_01861 2.9e-31
MLNPHKMC_01862 9.4e-09
MLNPHKMC_01864 4.6e-250 M nucleic acid phosphodiester bond hydrolysis
MLNPHKMC_01865 3e-31
MLNPHKMC_01867 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
MLNPHKMC_01868 4.3e-68 glnR K transcriptional
MLNPHKMC_01869 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MLNPHKMC_01870 2.3e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLNPHKMC_01871 1.7e-176 spoVK O stage V sporulation protein K
MLNPHKMC_01872 6.3e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLNPHKMC_01873 2.2e-108 ymaB
MLNPHKMC_01874 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLNPHKMC_01875 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLNPHKMC_01876 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MLNPHKMC_01877 4.5e-22 ymzA
MLNPHKMC_01878 8.2e-23
MLNPHKMC_01879 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MLNPHKMC_01880 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MLNPHKMC_01881 2.1e-46 ymaF S YmaF family
MLNPHKMC_01883 1.2e-49 ebrA P Small Multidrug Resistance protein
MLNPHKMC_01884 6.2e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
MLNPHKMC_01885 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
MLNPHKMC_01886 2.1e-126 ymaC S Replication protein
MLNPHKMC_01887 1.9e-07 K Transcriptional regulator
MLNPHKMC_01888 7.3e-250 aprX O Belongs to the peptidase S8 family
MLNPHKMC_01889 2.1e-162 ymaE S Metallo-beta-lactamase superfamily
MLNPHKMC_01890 4.4e-61 ymzB
MLNPHKMC_01891 6.3e-232 cypA C Cytochrome P450
MLNPHKMC_01892 0.0 pks13 HQ Beta-ketoacyl synthase
MLNPHKMC_01893 0.0 dhbF IQ polyketide synthase
MLNPHKMC_01894 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
MLNPHKMC_01895 0.0 pfaA Q Polyketide synthase of type I
MLNPHKMC_01896 0.0 rhiB IQ polyketide synthase
MLNPHKMC_01897 1e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
MLNPHKMC_01898 2.2e-142 pksH 4.2.1.18 I enoyl-CoA hydratase
MLNPHKMC_01899 1.5e-244 pksG 2.3.3.10 I synthase
MLNPHKMC_01900 1.7e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLNPHKMC_01901 7e-37 acpK IQ Phosphopantetheine attachment site
MLNPHKMC_01902 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MLNPHKMC_01903 4e-181 pksD Q Acyl transferase domain
MLNPHKMC_01905 2.4e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MLNPHKMC_01906 6.3e-125 pksB 3.1.2.6 S Polyketide biosynthesis
MLNPHKMC_01907 4.9e-108 pksA K Transcriptional regulator
MLNPHKMC_01908 3e-96 ymcC S Membrane
MLNPHKMC_01910 7.5e-69 S Regulatory protein YrvL
MLNPHKMC_01911 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MLNPHKMC_01912 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MLNPHKMC_01913 2.2e-88 cotE S Spore coat protein
MLNPHKMC_01914 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MLNPHKMC_01915 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MLNPHKMC_01916 8e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLNPHKMC_01917 2.1e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MLNPHKMC_01918 1.2e-36 spoVS S Stage V sporulation protein S
MLNPHKMC_01919 1.9e-152 ymdB S protein conserved in bacteria
MLNPHKMC_01920 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
MLNPHKMC_01921 5.3e-212 pbpX V Beta-lactamase
MLNPHKMC_01922 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MLNPHKMC_01923 5.6e-236 cinA 3.5.1.42 S Belongs to the CinA family
MLNPHKMC_01924 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLNPHKMC_01925 1.9e-124 ymfM S protein conserved in bacteria
MLNPHKMC_01926 2.7e-143 ymfK S Protein of unknown function (DUF3388)
MLNPHKMC_01927 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
MLNPHKMC_01928 1.7e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MLNPHKMC_01929 1.4e-242 ymfH S zinc protease
MLNPHKMC_01930 2.3e-232 ymfF S Peptidase M16
MLNPHKMC_01931 3.2e-204 ymfD EGP Major facilitator Superfamily
MLNPHKMC_01932 1.4e-133 ymfC K Transcriptional regulator
MLNPHKMC_01933 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MLNPHKMC_01934 4.4e-32 S YlzJ-like protein
MLNPHKMC_01935 1.5e-132 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MLNPHKMC_01936 1.6e-307 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLNPHKMC_01937 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLNPHKMC_01938 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MLNPHKMC_01939 1.6e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLNPHKMC_01940 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MLNPHKMC_01941 8.6e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MLNPHKMC_01942 1.3e-41 ymxH S YlmC YmxH family
MLNPHKMC_01943 4.4e-233 pepR S Belongs to the peptidase M16 family
MLNPHKMC_01944 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MLNPHKMC_01945 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MLNPHKMC_01946 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MLNPHKMC_01947 1.5e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MLNPHKMC_01948 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MLNPHKMC_01949 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MLNPHKMC_01950 3.9e-44 ylxP S protein conserved in bacteria
MLNPHKMC_01951 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MLNPHKMC_01952 3.1e-47 ylxQ J ribosomal protein
MLNPHKMC_01953 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
MLNPHKMC_01954 1.1e-203 nusA K Participates in both transcription termination and antitermination
MLNPHKMC_01955 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
MLNPHKMC_01956 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLNPHKMC_01957 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MLNPHKMC_01958 7.7e-233 rasP M zinc metalloprotease
MLNPHKMC_01959 1.7e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MLNPHKMC_01960 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
MLNPHKMC_01961 1.4e-144 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MLNPHKMC_01962 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MLNPHKMC_01963 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MLNPHKMC_01964 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MLNPHKMC_01965 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
MLNPHKMC_01966 3.1e-76 ylxL
MLNPHKMC_01967 7.4e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLNPHKMC_01968 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MLNPHKMC_01969 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MLNPHKMC_01970 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
MLNPHKMC_01971 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MLNPHKMC_01972 2.2e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MLNPHKMC_01973 2.8e-157 flhG D Belongs to the ParA family
MLNPHKMC_01974 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
MLNPHKMC_01975 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLNPHKMC_01976 4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLNPHKMC_01977 3.6e-132 fliR N Flagellar biosynthetic protein FliR
MLNPHKMC_01978 2.2e-36 fliQ N Role in flagellar biosynthesis
MLNPHKMC_01979 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
MLNPHKMC_01980 1.3e-95 fliZ N Flagellar biosynthesis protein, FliO
MLNPHKMC_01981 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
MLNPHKMC_01982 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLNPHKMC_01983 7e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLNPHKMC_01984 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
MLNPHKMC_01985 1.6e-135 flgG N Flagellar basal body rod
MLNPHKMC_01986 1.7e-72 flgD N Flagellar basal body rod modification protein
MLNPHKMC_01987 7.8e-205 fliK N Flagellar hook-length control protein
MLNPHKMC_01988 4.2e-35 ylxF S MgtE intracellular N domain
MLNPHKMC_01989 1.5e-69 fliJ N Flagellar biosynthesis chaperone
MLNPHKMC_01990 3.6e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MLNPHKMC_01991 9.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MLNPHKMC_01992 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLNPHKMC_01993 7e-255 fliF N The M ring may be actively involved in energy transduction
MLNPHKMC_01994 1.9e-31 fliE N Flagellar hook-basal body
MLNPHKMC_01995 3.4e-74 flgC N Belongs to the flagella basal body rod proteins family
MLNPHKMC_01996 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MLNPHKMC_01997 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MLNPHKMC_01998 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MLNPHKMC_01999 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MLNPHKMC_02000 2.5e-169 xerC L tyrosine recombinase XerC
MLNPHKMC_02001 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MLNPHKMC_02002 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLNPHKMC_02003 8e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MLNPHKMC_02004 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MLNPHKMC_02005 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MLNPHKMC_02006 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MLNPHKMC_02007 1.8e-288 ylqG
MLNPHKMC_02008 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLNPHKMC_02009 7.9e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MLNPHKMC_02010 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MLNPHKMC_02011 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MLNPHKMC_02012 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MLNPHKMC_02013 1.4e-60 ylqD S YlqD protein
MLNPHKMC_02014 4.5e-36 ylqC S Belongs to the UPF0109 family
MLNPHKMC_02015 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MLNPHKMC_02016 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MLNPHKMC_02017 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MLNPHKMC_02018 2.9e-87
MLNPHKMC_02019 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MLNPHKMC_02020 0.0 smc D Required for chromosome condensation and partitioning
MLNPHKMC_02021 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MLNPHKMC_02022 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLNPHKMC_02023 6.1e-129 IQ reductase
MLNPHKMC_02024 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MLNPHKMC_02025 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MLNPHKMC_02026 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MLNPHKMC_02027 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MLNPHKMC_02028 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
MLNPHKMC_02029 5.6e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MLNPHKMC_02030 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
MLNPHKMC_02031 5.5e-59 asp S protein conserved in bacteria
MLNPHKMC_02032 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MLNPHKMC_02033 4.5e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
MLNPHKMC_02034 9.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MLNPHKMC_02035 2.1e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MLNPHKMC_02036 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MLNPHKMC_02037 1.6e-140 stp 3.1.3.16 T phosphatase
MLNPHKMC_02038 9e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MLNPHKMC_02039 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MLNPHKMC_02040 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MLNPHKMC_02041 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLNPHKMC_02042 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLNPHKMC_02043 4.1e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLNPHKMC_02044 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MLNPHKMC_02045 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MLNPHKMC_02046 1.5e-40 ylzA S Belongs to the UPF0296 family
MLNPHKMC_02047 2.4e-156 yloC S stress-induced protein
MLNPHKMC_02048 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MLNPHKMC_02049 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MLNPHKMC_02050 1.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MLNPHKMC_02051 4.1e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MLNPHKMC_02052 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MLNPHKMC_02053 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MLNPHKMC_02054 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MLNPHKMC_02055 1.4e-179 cysP P phosphate transporter
MLNPHKMC_02056 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MLNPHKMC_02058 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MLNPHKMC_02059 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MLNPHKMC_02060 1.7e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MLNPHKMC_02061 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MLNPHKMC_02062 0.0 carB 6.3.5.5 F Belongs to the CarB family
MLNPHKMC_02063 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MLNPHKMC_02064 1e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MLNPHKMC_02065 9e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MLNPHKMC_02066 9e-232 pyrP F Xanthine uracil
MLNPHKMC_02067 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MLNPHKMC_02068 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLNPHKMC_02069 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MLNPHKMC_02070 3.8e-63 dksA T COG1734 DnaK suppressor protein
MLNPHKMC_02071 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MLNPHKMC_02072 2.6e-67 divIVA D Cell division initiation protein
MLNPHKMC_02073 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MLNPHKMC_02074 1.6e-39 yggT S membrane
MLNPHKMC_02075 6.7e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MLNPHKMC_02076 3.6e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MLNPHKMC_02077 7e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MLNPHKMC_02078 2.4e-37 ylmC S sporulation protein
MLNPHKMC_02079 1e-253 argE 3.5.1.16 E Acetylornithine deacetylase
MLNPHKMC_02080 5.3e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MLNPHKMC_02081 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLNPHKMC_02082 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLNPHKMC_02083 1.7e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MLNPHKMC_02084 0.0 bpr O COG1404 Subtilisin-like serine proteases
MLNPHKMC_02085 2.9e-202 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLNPHKMC_02086 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MLNPHKMC_02087 6.2e-58 sbp S small basic protein
MLNPHKMC_02088 1.3e-102 ylxX S protein conserved in bacteria
MLNPHKMC_02089 2.4e-103 ylxW S protein conserved in bacteria
MLNPHKMC_02090 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MLNPHKMC_02091 9e-167 murB 1.3.1.98 M cell wall formation
MLNPHKMC_02092 1.6e-199 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLNPHKMC_02093 5.7e-186 spoVE D Belongs to the SEDS family
MLNPHKMC_02094 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MLNPHKMC_02095 9.3e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MLNPHKMC_02096 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLNPHKMC_02097 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MLNPHKMC_02098 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MLNPHKMC_02099 3.7e-44 ftsL D Essential cell division protein
MLNPHKMC_02100 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MLNPHKMC_02101 2.9e-78 mraZ K Belongs to the MraZ family
MLNPHKMC_02102 1.2e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MLNPHKMC_02103 3e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLNPHKMC_02104 1.5e-88 ylbP K n-acetyltransferase
MLNPHKMC_02105 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MLNPHKMC_02106 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MLNPHKMC_02107 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
MLNPHKMC_02109 1.1e-228 ylbM S Belongs to the UPF0348 family
MLNPHKMC_02110 7.5e-186 ylbL T Belongs to the peptidase S16 family
MLNPHKMC_02111 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
MLNPHKMC_02112 3.6e-219 ylbJ S Sporulation integral membrane protein YlbJ
MLNPHKMC_02113 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MLNPHKMC_02114 1.9e-95 rsmD 2.1.1.171 L Methyltransferase
MLNPHKMC_02115 7.5e-39 ylbG S UPF0298 protein
MLNPHKMC_02116 1.8e-75 ylbF S Belongs to the UPF0342 family
MLNPHKMC_02117 6.7e-37 ylbE S YlbE-like protein
MLNPHKMC_02118 2.6e-62 ylbD S Putative coat protein
MLNPHKMC_02119 3.7e-199 ylbC S protein with SCP PR1 domains
MLNPHKMC_02120 2.6e-74 ylbB T COG0517 FOG CBS domain
MLNPHKMC_02121 7e-62 ylbA S YugN-like family
MLNPHKMC_02122 1.3e-165 ctaG S cytochrome c oxidase
MLNPHKMC_02123 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MLNPHKMC_02124 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MLNPHKMC_02125 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLNPHKMC_02126 8.9e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MLNPHKMC_02127 4.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLNPHKMC_02128 8.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MLNPHKMC_02129 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MLNPHKMC_02130 2.5e-212 ftsW D Belongs to the SEDS family
MLNPHKMC_02131 8.7e-44 ylaN S Belongs to the UPF0358 family
MLNPHKMC_02132 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
MLNPHKMC_02133 5.1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MLNPHKMC_02134 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MLNPHKMC_02135 1.2e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLNPHKMC_02136 5.6e-32 ylaI S protein conserved in bacteria
MLNPHKMC_02137 4.2e-47 ylaH S YlaH-like protein
MLNPHKMC_02138 0.0 typA T GTP-binding protein TypA
MLNPHKMC_02139 8.2e-22 S Family of unknown function (DUF5325)
MLNPHKMC_02140 2.6e-37 ylaE
MLNPHKMC_02141 4.5e-11 sigC S Putative zinc-finger
MLNPHKMC_02142 3.3e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
MLNPHKMC_02143 1.3e-41 ylaB
MLNPHKMC_02144 0.0 ylaA
MLNPHKMC_02145 3.7e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
MLNPHKMC_02146 3.5e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MLNPHKMC_02147 1.7e-76 ykzC S Acetyltransferase (GNAT) family
MLNPHKMC_02148 1.7e-148 suhB 3.1.3.25 G Inositol monophosphatase
MLNPHKMC_02149 7.1e-26 ykzI
MLNPHKMC_02150 4.6e-117 yktB S Belongs to the UPF0637 family
MLNPHKMC_02151 1.7e-41 yktA S Belongs to the UPF0223 family
MLNPHKMC_02152 1e-276 speA 4.1.1.19 E Arginine
MLNPHKMC_02153 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
MLNPHKMC_02154 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLNPHKMC_02155 2.2e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLNPHKMC_02156 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLNPHKMC_02157 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLNPHKMC_02158 7.4e-107 recN L Putative cell-wall binding lipoprotein
MLNPHKMC_02160 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLNPHKMC_02161 5.5e-147 ykrA S hydrolases of the HAD superfamily
MLNPHKMC_02162 8.2e-31 ykzG S Belongs to the UPF0356 family
MLNPHKMC_02163 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLNPHKMC_02164 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MLNPHKMC_02165 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
MLNPHKMC_02166 6.5e-156 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
MLNPHKMC_02167 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MLNPHKMC_02168 1.5e-43 abrB K of stationary sporulation gene expression
MLNPHKMC_02169 7.7e-183 mreB D Rod-share determining protein MreBH
MLNPHKMC_02170 1.1e-12 S Uncharacterized protein YkpC
MLNPHKMC_02171 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MLNPHKMC_02172 3.1e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLNPHKMC_02173 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLNPHKMC_02174 8.1e-39 ykoA
MLNPHKMC_02175 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLNPHKMC_02176 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MLNPHKMC_02177 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MLNPHKMC_02178 2.6e-135 fruR K Transcriptional regulator
MLNPHKMC_02179 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
MLNPHKMC_02180 9.4e-124 macB V ABC transporter, ATP-binding protein
MLNPHKMC_02181 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLNPHKMC_02182 6.1e-115 yknW S Yip1 domain
MLNPHKMC_02183 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLNPHKMC_02184 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLNPHKMC_02185 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MLNPHKMC_02186 1.4e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MLNPHKMC_02187 1.1e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MLNPHKMC_02188 1.2e-244 moeA 2.10.1.1 H molybdopterin
MLNPHKMC_02189 2.2e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLNPHKMC_02190 9.6e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MLNPHKMC_02191 2.1e-145 yknT
MLNPHKMC_02192 1.5e-93 rok K Repressor of ComK
MLNPHKMC_02193 4.1e-80 ykuV CO thiol-disulfide
MLNPHKMC_02194 3.9e-101 ykuU O Alkyl hydroperoxide reductase
MLNPHKMC_02195 8.8e-142 ykuT M Mechanosensitive ion channel
MLNPHKMC_02196 9e-37 ykuS S Belongs to the UPF0180 family
MLNPHKMC_02197 2.1e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MLNPHKMC_02198 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MLNPHKMC_02199 3.9e-78 fld C Flavodoxin
MLNPHKMC_02200 5.2e-175 ykuO
MLNPHKMC_02201 5.9e-85 fld C Flavodoxin domain
MLNPHKMC_02202 3.5e-168 ccpC K Transcriptional regulator
MLNPHKMC_02203 1.6e-76 ykuL S CBS domain
MLNPHKMC_02204 3.9e-27 ykzF S Antirepressor AbbA
MLNPHKMC_02205 4.4e-94 ykuK S Ribonuclease H-like
MLNPHKMC_02206 3.9e-37 ykuJ S protein conserved in bacteria
MLNPHKMC_02207 2e-233 ykuI T Diguanylate phosphodiesterase
MLNPHKMC_02208 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLNPHKMC_02209 8e-165 ykuE S Metallophosphoesterase
MLNPHKMC_02210 4.6e-88 ykuD S protein conserved in bacteria
MLNPHKMC_02211 2.8e-238 ykuC EGP Major facilitator Superfamily
MLNPHKMC_02212 1.7e-84 ykyB S YkyB-like protein
MLNPHKMC_02213 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
MLNPHKMC_02214 1.3e-15
MLNPHKMC_02215 3.3e-222 patA 2.6.1.1 E Aminotransferase
MLNPHKMC_02216 0.0 pilS 2.7.13.3 T Histidine kinase
MLNPHKMC_02217 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
MLNPHKMC_02218 3e-123 ykwD J protein with SCP PR1 domains
MLNPHKMC_02219 3.5e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
MLNPHKMC_02220 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MLNPHKMC_02221 4.1e-257 mcpC NT chemotaxis protein
MLNPHKMC_02222 3.2e-47 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLNPHKMC_02223 1.9e-44 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLNPHKMC_02224 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
MLNPHKMC_02225 7.2e-39 splA S Transcriptional regulator
MLNPHKMC_02226 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MLNPHKMC_02227 2.1e-39 ptsH G phosphocarrier protein HPr
MLNPHKMC_02228 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLNPHKMC_02229 7.6e-128 glcT K antiterminator
MLNPHKMC_02231 1.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
MLNPHKMC_02233 2.5e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MLNPHKMC_02234 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MLNPHKMC_02235 1.2e-88 stoA CO thiol-disulfide
MLNPHKMC_02236 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLNPHKMC_02237 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
MLNPHKMC_02238 2.7e-28
MLNPHKMC_02239 6e-25 ykvS S protein conserved in bacteria
MLNPHKMC_02240 5.6e-46 ykvR S Protein of unknown function (DUF3219)
MLNPHKMC_02241 2e-161 G Glycosyl hydrolases family 18
MLNPHKMC_02242 3.5e-35 3.5.1.104 M LysM domain
MLNPHKMC_02243 4.9e-215 ykvP 3.5.1.28 M Glycosyl transferases group 1
MLNPHKMC_02244 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
MLNPHKMC_02245 2e-61 ykvN K Transcriptional regulator
MLNPHKMC_02246 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MLNPHKMC_02247 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MLNPHKMC_02248 6.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MLNPHKMC_02249 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MLNPHKMC_02250 6.2e-180 ykvI S membrane
MLNPHKMC_02251 0.0 clpE O Belongs to the ClpA ClpB family
MLNPHKMC_02252 2.7e-138 motA N flagellar motor
MLNPHKMC_02253 2.5e-125 motB N Flagellar motor protein
MLNPHKMC_02254 1.3e-75 ykvE K transcriptional
MLNPHKMC_02255 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
MLNPHKMC_02256 1.4e-64 eag
MLNPHKMC_02257 6.4e-09 S Spo0E like sporulation regulatory protein
MLNPHKMC_02258 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
MLNPHKMC_02259 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MLNPHKMC_02260 1.4e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MLNPHKMC_02261 1.9e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MLNPHKMC_02262 1.2e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MLNPHKMC_02263 8e-232 mtnE 2.6.1.83 E Aminotransferase
MLNPHKMC_02264 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLNPHKMC_02265 1.2e-227 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MLNPHKMC_02266 6.3e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MLNPHKMC_02268 5.9e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLNPHKMC_02269 0.0 kinE 2.7.13.3 T Histidine kinase
MLNPHKMC_02270 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MLNPHKMC_02271 4.1e-18 ykzE
MLNPHKMC_02272 1.2e-10 ydfR S Protein of unknown function (DUF421)
MLNPHKMC_02273 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
MLNPHKMC_02274 1.2e-155 htpX O Belongs to the peptidase M48B family
MLNPHKMC_02275 2.5e-124 ykrK S Domain of unknown function (DUF1836)
MLNPHKMC_02276 1.9e-26 sspD S small acid-soluble spore protein
MLNPHKMC_02277 1.6e-112 rsgI S Anti-sigma factor N-terminus
MLNPHKMC_02278 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLNPHKMC_02279 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MLNPHKMC_02280 2.7e-109 ykoX S membrane-associated protein
MLNPHKMC_02281 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
MLNPHKMC_02282 1.1e-158 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MLNPHKMC_02283 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MLNPHKMC_02284 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLNPHKMC_02285 0.0 ykoS
MLNPHKMC_02286 2.1e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
MLNPHKMC_02287 7.8e-97 ykoP G polysaccharide deacetylase
MLNPHKMC_02288 2.4e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MLNPHKMC_02289 1.3e-81 mhqR K transcriptional
MLNPHKMC_02290 6.9e-26 ykoL
MLNPHKMC_02291 1.3e-17
MLNPHKMC_02292 1.4e-53 tnrA K transcriptional
MLNPHKMC_02293 2.2e-222 mgtE P Acts as a magnesium transporter
MLNPHKMC_02296 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
MLNPHKMC_02297 3.1e-111 ykoI S Peptidase propeptide and YPEB domain
MLNPHKMC_02298 2e-242 ykoH 2.7.13.3 T Histidine kinase
MLNPHKMC_02299 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLNPHKMC_02300 5.7e-109 ykoF S YKOF-related Family
MLNPHKMC_02301 6.5e-97 ykoE S ABC-type cobalt transport system, permease component
MLNPHKMC_02302 6.1e-307 P ABC transporter, ATP-binding protein
MLNPHKMC_02303 3.4e-135 ykoC P Cobalt transport protein
MLNPHKMC_02304 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLNPHKMC_02305 1.7e-176 isp O Belongs to the peptidase S8 family
MLNPHKMC_02306 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MLNPHKMC_02307 8.1e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
MLNPHKMC_02308 5.5e-71 ohrB O Organic hydroperoxide resistance protein
MLNPHKMC_02309 9.7e-74 ohrR K COG1846 Transcriptional regulators
MLNPHKMC_02310 1.3e-70 ohrA O Organic hydroperoxide resistance protein
MLNPHKMC_02311 1.5e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MLNPHKMC_02312 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLNPHKMC_02313 1.1e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MLNPHKMC_02314 7e-50 ykkD P Multidrug resistance protein
MLNPHKMC_02315 3.5e-55 ykkC P Multidrug resistance protein
MLNPHKMC_02316 1.1e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLNPHKMC_02317 6.7e-98 ykkA S Protein of unknown function (DUF664)
MLNPHKMC_02318 2.7e-129 ykjA S Protein of unknown function (DUF421)
MLNPHKMC_02319 1e-10
MLNPHKMC_02320 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MLNPHKMC_02321 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MLNPHKMC_02322 2.9e-159 ykgA E Amidinotransferase
MLNPHKMC_02323 6.9e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
MLNPHKMC_02324 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
MLNPHKMC_02325 1.8e-167 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLNPHKMC_02326 1.8e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MLNPHKMC_02327 2.4e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MLNPHKMC_02329 0.0 dppE E ABC transporter substrate-binding protein
MLNPHKMC_02330 2.7e-188 dppD P Belongs to the ABC transporter superfamily
MLNPHKMC_02331 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLNPHKMC_02332 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLNPHKMC_02333 5.1e-153 dppA E D-aminopeptidase
MLNPHKMC_02334 4.1e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
MLNPHKMC_02335 4e-211 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLNPHKMC_02337 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLNPHKMC_02338 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLNPHKMC_02339 4.6e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MLNPHKMC_02340 5.2e-240 steT E amino acid
MLNPHKMC_02341 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
MLNPHKMC_02342 9.9e-175 pit P phosphate transporter
MLNPHKMC_02343 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MLNPHKMC_02344 6.7e-23 spoIISB S Stage II sporulation protein SB
MLNPHKMC_02345 4.2e-161 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLNPHKMC_02346 9.3e-40 xhlB S SPP1 phage holin
MLNPHKMC_02347 3.9e-28 xhlA S Haemolysin XhlA
MLNPHKMC_02348 4.9e-14 xkdX
MLNPHKMC_02350 4e-100
MLNPHKMC_02351 6.7e-41
MLNPHKMC_02352 6.4e-102 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MLNPHKMC_02353 3.3e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MLNPHKMC_02354 9e-69 xkdS S Protein of unknown function (DUF2634)
MLNPHKMC_02355 2.1e-39 xkdR S Protein of unknown function (DUF2577)
MLNPHKMC_02356 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
MLNPHKMC_02357 8.3e-122 xkdP S Lysin motif
MLNPHKMC_02358 5.1e-311 xkdO L Transglycosylase SLT domain
MLNPHKMC_02359 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
MLNPHKMC_02360 6.1e-76 xkdM S Phage tail tube protein
MLNPHKMC_02361 3.6e-255 xkdK S Phage tail sheath C-terminal domain
MLNPHKMC_02362 1.9e-77 xkdJ
MLNPHKMC_02363 1.9e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
MLNPHKMC_02364 2.5e-64 yqbH S Domain of unknown function (DUF3599)
MLNPHKMC_02365 5.1e-63 yqbG S Protein of unknown function (DUF3199)
MLNPHKMC_02366 5.8e-169 xkdG S Phage capsid family
MLNPHKMC_02367 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MLNPHKMC_02368 1.6e-285 yqbA S portal protein
MLNPHKMC_02369 1.2e-252 xtmB S phage terminase, large subunit
MLNPHKMC_02370 1.2e-138 xtmA L phage terminase small subunit
MLNPHKMC_02371 1.6e-83 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MLNPHKMC_02372 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
MLNPHKMC_02375 6.4e-119 xkdC L Bacterial dnaA protein
MLNPHKMC_02376 5.9e-157 xkdB K sequence-specific DNA binding
MLNPHKMC_02378 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
MLNPHKMC_02379 1.6e-111 xkdA E IrrE N-terminal-like domain
MLNPHKMC_02380 4.4e-160 ydbD P Catalase
MLNPHKMC_02381 5.7e-109 yjqB S Pfam:DUF867
MLNPHKMC_02382 5.2e-60 yjqA S Bacterial PH domain
MLNPHKMC_02383 7.2e-167 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
MLNPHKMC_02384 6.3e-41 S YCII-related domain
MLNPHKMC_02386 1e-212 S response regulator aspartate phosphatase
MLNPHKMC_02387 2.1e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
MLNPHKMC_02388 2.3e-78 yjoA S DinB family
MLNPHKMC_02389 7.4e-130 MA20_18170 S membrane transporter protein
MLNPHKMC_02390 1.7e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MLNPHKMC_02391 4.9e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MLNPHKMC_02392 8.9e-184 exuR K transcriptional
MLNPHKMC_02393 8.3e-227 exuT G Sugar (and other) transporter
MLNPHKMC_02394 1.9e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLNPHKMC_02395 2.2e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MLNPHKMC_02396 1.9e-189 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
MLNPHKMC_02397 2.1e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MLNPHKMC_02398 2.7e-247 yjmB G symporter YjmB
MLNPHKMC_02399 7.9e-279 uxaC 5.3.1.12 G glucuronate isomerase
MLNPHKMC_02400 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
MLNPHKMC_02401 7.1e-66 yjlC S Protein of unknown function (DUF1641)
MLNPHKMC_02402 3.4e-91 yjlB S Cupin domain
MLNPHKMC_02403 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
MLNPHKMC_02404 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
MLNPHKMC_02405 5.6e-122 ybbM S transport system, permease component
MLNPHKMC_02406 1e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MLNPHKMC_02407 1.4e-29
MLNPHKMC_02408 3.8e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLNPHKMC_02409 2.3e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
MLNPHKMC_02411 1.5e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
MLNPHKMC_02413 4.3e-95 yjgD S Protein of unknown function (DUF1641)
MLNPHKMC_02414 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MLNPHKMC_02415 2e-103 yjgB S Domain of unknown function (DUF4309)
MLNPHKMC_02416 2.7e-45 T PhoQ Sensor
MLNPHKMC_02417 1.5e-112 yjfC O Predicted Zn-dependent protease (DUF2268)
MLNPHKMC_02418 2.3e-20 yjfB S Putative motility protein
MLNPHKMC_02419 1.2e-82 S Protein of unknown function (DUF2690)
MLNPHKMC_02420 9.3e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
MLNPHKMC_02422 5.2e-173 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLNPHKMC_02423 3.5e-52 yjdJ S Domain of unknown function (DUF4306)
MLNPHKMC_02424 4.2e-29 S Domain of unknown function (DUF4177)
MLNPHKMC_02425 5.2e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MLNPHKMC_02427 3.8e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
MLNPHKMC_02428 1.3e-48 yjdF S Protein of unknown function (DUF2992)
MLNPHKMC_02429 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
MLNPHKMC_02430 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
MLNPHKMC_02431 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
MLNPHKMC_02433 4.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
MLNPHKMC_02434 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
MLNPHKMC_02435 2.8e-67 S response regulator aspartate phosphatase
MLNPHKMC_02439 1.1e-13
MLNPHKMC_02440 2.1e-236 M nucleic acid phosphodiester bond hydrolysis
MLNPHKMC_02441 1e-29
MLNPHKMC_02442 1.6e-38
MLNPHKMC_02445 1.5e-30 gepA S Protein of unknown function (DUF4065)
MLNPHKMC_02446 0.0 M nucleic acid phosphodiester bond hydrolysis
MLNPHKMC_02447 4.6e-23
MLNPHKMC_02448 2e-104 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MLNPHKMC_02449 1.2e-57 S Bacteriophage holin family
MLNPHKMC_02454 3e-204 sidC L Phage minor structural protein
MLNPHKMC_02455 1.2e-50
MLNPHKMC_02456 3.7e-139
MLNPHKMC_02457 8.4e-29 S Phage tail assembly chaperone protein, TAC
MLNPHKMC_02458 7.5e-33 N Bacterial Ig-like domain 2
MLNPHKMC_02459 2.3e-29 S Protein of unknown function (DUF3168)
MLNPHKMC_02460 6.8e-37 S Bacteriophage HK97-gp10, putative tail-component
MLNPHKMC_02461 8.2e-28 S Phage head-tail joining protein
MLNPHKMC_02462 5.4e-28 S Phage gp6-like head-tail connector protein
MLNPHKMC_02465 2.3e-141 S Phage capsid family
MLNPHKMC_02466 2.3e-59 S Domain of unknown function (DUF4355)
MLNPHKMC_02469 2e-81 S Phage Mu protein F like protein
MLNPHKMC_02470 3.6e-207 S Phage portal protein, SPP1 Gp6-like
MLNPHKMC_02471 1e-216 S phage terminase, large subunit
MLNPHKMC_02472 1.7e-83 yqaS L DNA packaging
MLNPHKMC_02475 2.1e-13 K Transcriptional regulator
MLNPHKMC_02477 5.8e-70 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MLNPHKMC_02483 1.7e-25 yqaO S Phage-like element PBSX protein XtrA
MLNPHKMC_02485 7.5e-53 S Protein of unknown function (DUF1064)
MLNPHKMC_02487 5.9e-137 xkdC L IstB-like ATP binding protein
MLNPHKMC_02488 1.7e-68 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
MLNPHKMC_02489 5.8e-97
MLNPHKMC_02494 1e-67
MLNPHKMC_02495 4.7e-68 S DNA binding
MLNPHKMC_02496 5.8e-15 S Helix-turn-helix domain
MLNPHKMC_02497 5.8e-07 K Transcriptional
MLNPHKMC_02498 4.8e-21 xre K transcriptional
MLNPHKMC_02499 3.3e-49
MLNPHKMC_02500 1.8e-27 S Protein of unknown function (DUF4064)
MLNPHKMC_02501 1.7e-47 xkdA E IrrE N-terminal-like domain
MLNPHKMC_02502 4.9e-144 L Belongs to the 'phage' integrase family
MLNPHKMC_02504 2.4e-212 yjcL S Protein of unknown function (DUF819)
MLNPHKMC_02505 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
MLNPHKMC_02506 8.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MLNPHKMC_02507 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MLNPHKMC_02508 6.5e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
MLNPHKMC_02509 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MLNPHKMC_02510 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLNPHKMC_02511 1.7e-38
MLNPHKMC_02512 0.0 yjcD 3.6.4.12 L DNA helicase
MLNPHKMC_02513 2.9e-38 spoVIF S Stage VI sporulation protein F
MLNPHKMC_02516 1.9e-56 yjcA S Protein of unknown function (DUF1360)
MLNPHKMC_02517 3e-55 cotV S Spore Coat Protein X and V domain
MLNPHKMC_02518 9.9e-23 cotW
MLNPHKMC_02519 4e-71 cotX S Spore Coat Protein X and V domain
MLNPHKMC_02520 3.4e-96 cotY S Spore coat protein Z
MLNPHKMC_02521 2e-82 cotZ S Spore coat protein
MLNPHKMC_02522 2.5e-52 yjbX S Spore coat protein
MLNPHKMC_02523 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MLNPHKMC_02524 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MLNPHKMC_02525 2.3e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLNPHKMC_02526 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MLNPHKMC_02527 6.7e-30 thiS H thiamine diphosphate biosynthetic process
MLNPHKMC_02528 1.7e-215 thiO 1.4.3.19 E Glycine oxidase
MLNPHKMC_02529 3.2e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
MLNPHKMC_02530 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MLNPHKMC_02531 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MLNPHKMC_02532 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MLNPHKMC_02533 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLNPHKMC_02534 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLNPHKMC_02535 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
MLNPHKMC_02536 2.1e-61 yjbL S Belongs to the UPF0738 family
MLNPHKMC_02537 4.6e-100 yjbK S protein conserved in bacteria
MLNPHKMC_02538 8.5e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLNPHKMC_02539 3.7e-72 yjbI S Bacterial-like globin
MLNPHKMC_02540 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MLNPHKMC_02541 1.8e-20
MLNPHKMC_02542 0.0 pepF E oligoendopeptidase F
MLNPHKMC_02543 5.8e-219 yjbF S Competence protein
MLNPHKMC_02544 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLNPHKMC_02545 1.3e-111 yjbE P Integral membrane protein TerC family
MLNPHKMC_02546 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MLNPHKMC_02547 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLNPHKMC_02548 2.3e-202 yjbB EGP Major Facilitator Superfamily
MLNPHKMC_02549 1.2e-171 oppF E Belongs to the ABC transporter superfamily
MLNPHKMC_02550 1.3e-196 oppD P Belongs to the ABC transporter superfamily
MLNPHKMC_02551 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLNPHKMC_02552 8.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLNPHKMC_02553 9.4e-308 oppA E ABC transporter substrate-binding protein
MLNPHKMC_02554 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MLNPHKMC_02555 5e-147 yjbA S Belongs to the UPF0736 family
MLNPHKMC_02556 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLNPHKMC_02557 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLNPHKMC_02558 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
MLNPHKMC_02559 1.2e-185 appF E Belongs to the ABC transporter superfamily
MLNPHKMC_02560 8.8e-184 appD P Belongs to the ABC transporter superfamily
MLNPHKMC_02561 3.3e-149 yjaZ O Zn-dependent protease
MLNPHKMC_02562 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLNPHKMC_02563 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLNPHKMC_02564 3.9e-10 yjzB
MLNPHKMC_02565 7.3e-26 comZ S ComZ
MLNPHKMC_02566 2.5e-183 med S Transcriptional activator protein med
MLNPHKMC_02567 5.8e-100 yjaV
MLNPHKMC_02568 2.4e-141 yjaU I carboxylic ester hydrolase activity
MLNPHKMC_02569 2.3e-16 yjzD S Protein of unknown function (DUF2929)
MLNPHKMC_02570 9.5e-28 yjzC S YjzC-like protein
MLNPHKMC_02571 1.1e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MLNPHKMC_02572 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MLNPHKMC_02573 4.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MLNPHKMC_02574 6.4e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MLNPHKMC_02575 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MLNPHKMC_02576 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MLNPHKMC_02577 1.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MLNPHKMC_02578 1.7e-88 norB G Major Facilitator Superfamily
MLNPHKMC_02579 3.4e-269 yitY C D-arabinono-1,4-lactone oxidase
MLNPHKMC_02580 1.5e-22 pilT S Proteolipid membrane potential modulator
MLNPHKMC_02581 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
MLNPHKMC_02582 5e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MLNPHKMC_02583 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MLNPHKMC_02585 1.2e-17 S Protein of unknown function (DUF3813)
MLNPHKMC_02586 5e-73 ipi S Intracellular proteinase inhibitor
MLNPHKMC_02587 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MLNPHKMC_02588 2.5e-158 yitS S protein conserved in bacteria
MLNPHKMC_02589 1.2e-307 nprB 3.4.24.28 E Peptidase M4
MLNPHKMC_02590 1.4e-44 yitR S Domain of unknown function (DUF3784)
MLNPHKMC_02591 2.5e-93
MLNPHKMC_02592 1.5e-58 K Transcriptional regulator PadR-like family
MLNPHKMC_02593 5.8e-97 S Sporulation delaying protein SdpA
MLNPHKMC_02594 2.6e-169
MLNPHKMC_02595 8.5e-94
MLNPHKMC_02596 3.4e-160 cvfB S protein conserved in bacteria
MLNPHKMC_02597 5.6e-54 yajQ S Belongs to the UPF0234 family
MLNPHKMC_02598 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MLNPHKMC_02599 1e-70 yjcF S Acetyltransferase (GNAT) domain
MLNPHKMC_02600 1.8e-153 yitH K Acetyltransferase (GNAT) domain
MLNPHKMC_02601 2e-228 yitG EGP Major facilitator Superfamily
MLNPHKMC_02602 1.2e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MLNPHKMC_02603 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLNPHKMC_02604 1.6e-140 yitD 4.4.1.19 S synthase
MLNPHKMC_02605 7.6e-118 comB 3.1.3.71 H Belongs to the ComB family
MLNPHKMC_02606 7.3e-140 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MLNPHKMC_02607 1.3e-231 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MLNPHKMC_02608 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MLNPHKMC_02609 3.5e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLNPHKMC_02610 7.5e-35 mcbG S Pentapeptide repeats (9 copies)
MLNPHKMC_02611 6.5e-232 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLNPHKMC_02612 1.2e-27 L Recombinase
MLNPHKMC_02613 2e-20 L Recombinase
MLNPHKMC_02614 2.4e-114 L Recombinase
MLNPHKMC_02615 2.5e-13
MLNPHKMC_02621 1.9e-13
MLNPHKMC_02622 1.1e-11
MLNPHKMC_02623 5.7e-37
MLNPHKMC_02624 3.6e-101 S Restriction endonuclease NotI
MLNPHKMC_02625 1.2e-136 2.1.1.113, 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MLNPHKMC_02626 4e-79 S Domain of unknown function (DUF4145)
MLNPHKMC_02627 4e-22 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLNPHKMC_02628 2.7e-106 argO S Lysine exporter protein LysE YggA
MLNPHKMC_02629 1.8e-92 yisT S DinB family
MLNPHKMC_02630 4e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
MLNPHKMC_02631 1e-182 purR K helix_turn _helix lactose operon repressor
MLNPHKMC_02632 1.2e-160 yisR K Transcriptional regulator
MLNPHKMC_02633 4e-243 yisQ V Mate efflux family protein
MLNPHKMC_02634 3.8e-145 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
MLNPHKMC_02635 4.7e-88 yizA S Damage-inducible protein DinB
MLNPHKMC_02636 0.0 asnO 6.3.5.4 E Asparagine synthase
MLNPHKMC_02637 2.6e-100 yisN S Protein of unknown function (DUF2777)
MLNPHKMC_02638 0.0 wprA O Belongs to the peptidase S8 family
MLNPHKMC_02639 3e-57 yisL S UPF0344 protein
MLNPHKMC_02640 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MLNPHKMC_02641 1e-90 cotH M Spore Coat
MLNPHKMC_02642 1.5e-22 yisI S Spo0E like sporulation regulatory protein
MLNPHKMC_02643 1.9e-33 gerPA S Spore germination protein
MLNPHKMC_02644 4e-34 gerPB S cell differentiation
MLNPHKMC_02645 7e-54 gerPC S Spore germination protein
MLNPHKMC_02646 3.1e-23 gerPD S Spore germination protein
MLNPHKMC_02647 7.5e-65 gerPE S Spore germination protein GerPE
MLNPHKMC_02648 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
MLNPHKMC_02649 1.1e-49 yisB V COG1403 Restriction endonuclease
MLNPHKMC_02650 0.0 sbcC L COG0419 ATPase involved in DNA repair
MLNPHKMC_02651 5.9e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MLNPHKMC_02652 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MLNPHKMC_02653 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MLNPHKMC_02654 2.4e-77 yhjR S Rubrerythrin
MLNPHKMC_02655 1.3e-35 yhjQ C COG1145 Ferredoxin
MLNPHKMC_02656 0.0 S Sugar transport-related sRNA regulator N-term
MLNPHKMC_02657 3.7e-208 EGP Transmembrane secretion effector
MLNPHKMC_02658 9.3e-201 abrB S membrane
MLNPHKMC_02659 6.5e-187 yhjM 5.1.1.1 K Transcriptional regulator
MLNPHKMC_02660 1.6e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MLNPHKMC_02661 1.5e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
MLNPHKMC_02662 3.5e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
MLNPHKMC_02663 8.5e-213 glcP G Major Facilitator Superfamily
MLNPHKMC_02666 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
MLNPHKMC_02667 8.4e-279 yhjG CH FAD binding domain
MLNPHKMC_02668 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
MLNPHKMC_02669 9.1e-110 yhjE S SNARE associated Golgi protein
MLNPHKMC_02670 1.1e-59 yhjD
MLNPHKMC_02671 6.9e-27 yhjC S Protein of unknown function (DUF3311)
MLNPHKMC_02672 4.9e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLNPHKMC_02673 1.2e-39 yhjA S Excalibur calcium-binding domain
MLNPHKMC_02674 2.3e-167 IQ Enoyl-(Acyl carrier protein) reductase
MLNPHKMC_02675 4.2e-109 comK K Competence transcription factor
MLNPHKMC_02676 1.3e-32 yhzC S IDEAL
MLNPHKMC_02677 4.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLNPHKMC_02678 3e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MLNPHKMC_02679 4.9e-182 hemAT NT chemotaxis protein
MLNPHKMC_02680 5e-91 bioY S BioY family
MLNPHKMC_02681 3e-273 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MLNPHKMC_02682 8.5e-196 vraB 2.3.1.9 I Belongs to the thiolase family
MLNPHKMC_02683 2.1e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MLNPHKMC_02684 4.3e-157 yfmC M Periplasmic binding protein
MLNPHKMC_02685 3.1e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
MLNPHKMC_02686 4.3e-77 VY92_01935 K acetyltransferase
MLNPHKMC_02687 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
MLNPHKMC_02688 1.2e-241 yhfN 3.4.24.84 O Peptidase M48
MLNPHKMC_02689 1.3e-64 yhfM
MLNPHKMC_02690 6.8e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MLNPHKMC_02691 1.3e-111 yhfK GM NmrA-like family
MLNPHKMC_02692 8.3e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
MLNPHKMC_02693 3.1e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MLNPHKMC_02694 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLNPHKMC_02695 3.7e-72 3.4.13.21 S ASCH
MLNPHKMC_02696 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
MLNPHKMC_02697 7e-136 yhfC S Putative membrane peptidase family (DUF2324)
MLNPHKMC_02698 3.9e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLNPHKMC_02699 3.9e-214 yhgE S YhgE Pip N-terminal domain protein
MLNPHKMC_02700 5.4e-101 yhgD K Transcriptional regulator
MLNPHKMC_02701 1.1e-264 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MLNPHKMC_02702 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MLNPHKMC_02703 1.2e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MLNPHKMC_02704 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MLNPHKMC_02705 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MLNPHKMC_02706 1.6e-33 1.15.1.2 C Rubrerythrin
MLNPHKMC_02707 1.7e-241 yhfA C membrane
MLNPHKMC_02708 5.4e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MLNPHKMC_02709 3.4e-113 ecsC S EcsC protein family
MLNPHKMC_02710 7e-215 ecsB U ABC transporter
MLNPHKMC_02711 4.6e-137 ecsA V transporter (ATP-binding protein)
MLNPHKMC_02712 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MLNPHKMC_02713 3.2e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MLNPHKMC_02714 3.6e-80 trpP S Tryptophan transporter TrpP
MLNPHKMC_02715 5.4e-21
MLNPHKMC_02716 8.2e-39 yhaH S YtxH-like protein
MLNPHKMC_02717 1e-113 hpr K Negative regulator of protease production and sporulation
MLNPHKMC_02718 1.3e-54 yhaI S Protein of unknown function (DUF1878)
MLNPHKMC_02719 1.9e-89 yhaK S Putative zincin peptidase
MLNPHKMC_02720 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MLNPHKMC_02721 1.6e-21 yhaL S Sporulation protein YhaL
MLNPHKMC_02722 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
MLNPHKMC_02723 0.0 yhaN L AAA domain
MLNPHKMC_02724 8.2e-224 yhaO L DNA repair exonuclease
MLNPHKMC_02725 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MLNPHKMC_02726 5.7e-166 yhaQ S ABC transporter, ATP-binding protein
MLNPHKMC_02727 2.4e-26 S YhzD-like protein
MLNPHKMC_02728 6.7e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
MLNPHKMC_02730 3e-87 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
MLNPHKMC_02731 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
MLNPHKMC_02732 5.1e-292 hemZ H coproporphyrinogen III oxidase
MLNPHKMC_02733 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
MLNPHKMC_02734 1.7e-204 yhaZ L DNA alkylation repair enzyme
MLNPHKMC_02735 9.5e-48 yheA S Belongs to the UPF0342 family
MLNPHKMC_02736 1.3e-202 yheB S Belongs to the UPF0754 family
MLNPHKMC_02737 2.4e-214 yheC HJ YheC/D like ATP-grasp
MLNPHKMC_02738 3.7e-265 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MLNPHKMC_02739 1.3e-36 yheE S Family of unknown function (DUF5342)
MLNPHKMC_02740 6.3e-28 sspB S spore protein
MLNPHKMC_02741 4.5e-109 yheG GM NAD(P)H-binding
MLNPHKMC_02742 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLNPHKMC_02743 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLNPHKMC_02744 1.7e-82 nhaX T Belongs to the universal stress protein A family
MLNPHKMC_02745 1.4e-227 nhaC C Na H antiporter
MLNPHKMC_02746 5.8e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MLNPHKMC_02747 1.9e-147 yheN G deacetylase
MLNPHKMC_02748 3.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MLNPHKMC_02749 9.9e-184 yhdY M Mechanosensitive ion channel
MLNPHKMC_02751 5.2e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MLNPHKMC_02752 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLNPHKMC_02753 1.1e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLNPHKMC_02754 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
MLNPHKMC_02755 2.4e-220 yhdR 2.6.1.1 E Aminotransferase
MLNPHKMC_02756 4.1e-74 cueR K transcriptional
MLNPHKMC_02757 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MLNPHKMC_02758 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLNPHKMC_02759 1.5e-191 yhdN C Aldo keto reductase
MLNPHKMC_02760 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
MLNPHKMC_02761 6.6e-201 yhdL S Sigma factor regulator N-terminal
MLNPHKMC_02762 8.1e-45 yhdK S Sigma-M inhibitor protein
MLNPHKMC_02763 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLNPHKMC_02764 1.2e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLNPHKMC_02765 4.4e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLNPHKMC_02766 1e-249 yhdG E amino acid
MLNPHKMC_02767 1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLNPHKMC_02768 1.2e-202 citA 2.3.3.1 C Belongs to the citrate synthase family
MLNPHKMC_02769 3.8e-162 citR K Transcriptional regulator
MLNPHKMC_02770 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MLNPHKMC_02771 3.7e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MLNPHKMC_02772 6.3e-276 ycgB S Stage V sporulation protein R
MLNPHKMC_02773 4.8e-237 ygxB M Conserved TM helix
MLNPHKMC_02774 1e-75 nsrR K Transcriptional regulator
MLNPHKMC_02775 8.7e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MLNPHKMC_02776 2e-52 yhdC S Protein of unknown function (DUF3889)
MLNPHKMC_02777 1.2e-38 yhdB S YhdB-like protein
MLNPHKMC_02778 1.2e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
MLNPHKMC_02779 5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLNPHKMC_02780 4e-212 yhcY 2.7.13.3 T Histidine kinase
MLNPHKMC_02781 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MLNPHKMC_02782 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MLNPHKMC_02783 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MLNPHKMC_02784 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MLNPHKMC_02785 2e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MLNPHKMC_02786 1.2e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLNPHKMC_02787 4.6e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLNPHKMC_02788 1.3e-119 yhcW 5.4.2.6 S hydrolase
MLNPHKMC_02789 9.9e-68 yhcV S COG0517 FOG CBS domain
MLNPHKMC_02790 1.3e-66 yhcU S Family of unknown function (DUF5365)
MLNPHKMC_02791 3e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLNPHKMC_02792 5.1e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MLNPHKMC_02793 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
MLNPHKMC_02794 8.9e-100 yhcQ M Spore coat protein
MLNPHKMC_02795 4.4e-164 yhcP
MLNPHKMC_02796 2.2e-65 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLNPHKMC_02797 4.1e-40 yhcM
MLNPHKMC_02798 1.2e-49 K Transcriptional regulator PadR-like family
MLNPHKMC_02799 8.3e-78 S Protein of unknown function (DUF2812)
MLNPHKMC_02800 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLNPHKMC_02801 4.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
MLNPHKMC_02802 1.1e-150 metQ M Belongs to the nlpA lipoprotein family
MLNPHKMC_02803 1e-30 cspB K Cold-shock protein
MLNPHKMC_02804 6.7e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLNPHKMC_02805 1.9e-164 yhcH V ABC transporter, ATP-binding protein
MLNPHKMC_02806 5.2e-122 yhcG V ABC transporter, ATP-binding protein
MLNPHKMC_02807 6.6e-60 yhcF K Transcriptional regulator
MLNPHKMC_02808 7.8e-55
MLNPHKMC_02809 2.8e-37 yhcC
MLNPHKMC_02810 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
MLNPHKMC_02811 2.9e-269 yhcA EGP Major facilitator Superfamily
MLNPHKMC_02812 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
MLNPHKMC_02813 2.2e-76 yhbI K DNA-binding transcription factor activity
MLNPHKMC_02814 2.5e-225 yhbH S Belongs to the UPF0229 family
MLNPHKMC_02815 0.0 prkA T Ser protein kinase
MLNPHKMC_02816 2.7e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
MLNPHKMC_02817 7.8e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MLNPHKMC_02818 1.2e-109 yhbD K Protein of unknown function (DUF4004)
MLNPHKMC_02819 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MLNPHKMC_02820 4.4e-177 yhbB S Putative amidase domain
MLNPHKMC_02821 3.9e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MLNPHKMC_02822 8.7e-113 yhzB S B3/4 domain
MLNPHKMC_02824 4.4e-29 K Transcriptional regulator
MLNPHKMC_02825 5.5e-75 ygaO
MLNPHKMC_02826 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLNPHKMC_02828 1.5e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MLNPHKMC_02829 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MLNPHKMC_02830 4.3e-170 ssuA M Sulfonate ABC transporter
MLNPHKMC_02831 3e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MLNPHKMC_02832 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MLNPHKMC_02834 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MLNPHKMC_02835 2.1e-100 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
MLNPHKMC_02836 1.2e-26
MLNPHKMC_02837 5e-142 spo0M S COG4326 Sporulation control protein
MLNPHKMC_02841 2e-08
MLNPHKMC_02849 7.8e-08
MLNPHKMC_02854 3.4e-39 S COG NOG14552 non supervised orthologous group
MLNPHKMC_02855 6.7e-167 ygxA S Nucleotidyltransferase-like
MLNPHKMC_02856 2.8e-55 ygzB S UPF0295 protein
MLNPHKMC_02857 4e-80 perR P Belongs to the Fur family
MLNPHKMC_02858 4.8e-87 bcp 1.11.1.15 O Peroxiredoxin
MLNPHKMC_02859 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MLNPHKMC_02860 8.7e-180 ygaE S Membrane
MLNPHKMC_02861 1.8e-301 ygaD V ABC transporter
MLNPHKMC_02862 1.3e-104 ygaC J Belongs to the UPF0374 family
MLNPHKMC_02863 3.3e-37 ygaB S YgaB-like protein
MLNPHKMC_02864 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
MLNPHKMC_02865 6.4e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLNPHKMC_02866 6.9e-36 yfhS
MLNPHKMC_02867 3.3e-210 mutY L A G-specific
MLNPHKMC_02868 1.2e-185 yfhP S membrane-bound metal-dependent
MLNPHKMC_02869 0.0 yfhO S Bacterial membrane protein YfhO
MLNPHKMC_02870 6.1e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLNPHKMC_02871 1.4e-169 yfhM S Alpha beta hydrolase
MLNPHKMC_02872 1e-47 yfhL S SdpI/YhfL protein family
MLNPHKMC_02873 2.4e-87 batE T Bacterial SH3 domain homologues
MLNPHKMC_02874 1.3e-44 yfhJ S WVELL protein
MLNPHKMC_02875 6.2e-20 sspK S reproduction
MLNPHKMC_02876 1.1e-209 yfhI EGP Major facilitator Superfamily
MLNPHKMC_02878 9.7e-52 yfhH S Protein of unknown function (DUF1811)
MLNPHKMC_02879 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
MLNPHKMC_02880 2.1e-171 yfhF S nucleoside-diphosphate sugar epimerase
MLNPHKMC_02882 2.1e-25 yfhD S YfhD-like protein
MLNPHKMC_02883 1.5e-106 yfhC C nitroreductase
MLNPHKMC_02884 1.1e-166 yfhB 5.3.3.17 S PhzF family
MLNPHKMC_02885 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLNPHKMC_02886 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLNPHKMC_02887 1.9e-175 yfiY P ABC transporter substrate-binding protein
MLNPHKMC_02888 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLNPHKMC_02889 4.9e-79 yfiV K transcriptional
MLNPHKMC_02890 3.4e-283 yfiU EGP Major facilitator Superfamily
MLNPHKMC_02891 4.7e-99 yfiT S Belongs to the metal hydrolase YfiT family
MLNPHKMC_02892 7.9e-214 yfiS EGP Major facilitator Superfamily
MLNPHKMC_02893 7.1e-107 yfiR K Transcriptional regulator
MLNPHKMC_02894 5.9e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MLNPHKMC_02895 3.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MLNPHKMC_02896 8.3e-99 padR K transcriptional
MLNPHKMC_02897 2.2e-202 V COG0842 ABC-type multidrug transport system, permease component
MLNPHKMC_02898 4.4e-206 V ABC-2 family transporter protein
MLNPHKMC_02899 2.4e-167 V ABC transporter, ATP-binding protein
MLNPHKMC_02900 2.8e-109 KT LuxR family transcriptional regulator
MLNPHKMC_02901 6.9e-188 yxjM T Histidine kinase
MLNPHKMC_02902 2e-160 yfiE 1.13.11.2 S glyoxalase
MLNPHKMC_02903 2.2e-64 mhqP S DoxX
MLNPHKMC_02904 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLNPHKMC_02905 1.9e-306 yfiB3 V ABC transporter
MLNPHKMC_02906 0.0 yobO M COG5434 Endopolygalacturonase
MLNPHKMC_02907 1.4e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLNPHKMC_02908 1e-139 glvR K Helix-turn-helix domain, rpiR family
MLNPHKMC_02909 4.2e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLNPHKMC_02910 3.3e-44 yfjA S Belongs to the WXG100 family
MLNPHKMC_02911 9.6e-172 yfjB
MLNPHKMC_02912 1.2e-124 yfjC
MLNPHKMC_02913 8.1e-86 S Family of unknown function (DUF5381)
MLNPHKMC_02914 4e-56 yfjF S UPF0060 membrane protein
MLNPHKMC_02915 5.8e-25 sspH S Belongs to the SspH family
MLNPHKMC_02916 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MLNPHKMC_02917 5.6e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLNPHKMC_02918 9.3e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLNPHKMC_02919 3.8e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLNPHKMC_02920 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLNPHKMC_02921 1.3e-29 yfjL
MLNPHKMC_02922 3.9e-86 yfjM S Psort location Cytoplasmic, score
MLNPHKMC_02923 1.8e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLNPHKMC_02924 3.9e-44 S YfzA-like protein
MLNPHKMC_02925 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLNPHKMC_02926 6.5e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MLNPHKMC_02927 1.7e-184 corA P Mediates influx of magnesium ions
MLNPHKMC_02928 5.2e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MLNPHKMC_02929 5.8e-154 pdaA G deacetylase
MLNPHKMC_02930 1.1e-26 yfjT
MLNPHKMC_02931 5.4e-222 yfkA S YfkB-like domain
MLNPHKMC_02932 6e-149 yfkC M Mechanosensitive ion channel
MLNPHKMC_02933 1.2e-146 yfkD S YfkD-like protein
MLNPHKMC_02934 6.1e-183 cax P COG0387 Ca2 H antiporter
MLNPHKMC_02935 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
MLNPHKMC_02936 5e-08
MLNPHKMC_02937 1.3e-143 yihY S Belongs to the UPF0761 family
MLNPHKMC_02938 2.4e-50 yfkI S gas vesicle protein
MLNPHKMC_02939 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLNPHKMC_02940 1.3e-28 yfkK S Belongs to the UPF0435 family
MLNPHKMC_02941 6.8e-207 ydiM EGP Major facilitator Superfamily
MLNPHKMC_02942 3.3e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
MLNPHKMC_02943 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MLNPHKMC_02944 1.1e-124 yfkO C nitroreductase
MLNPHKMC_02945 1.8e-133 treR K transcriptional
MLNPHKMC_02946 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MLNPHKMC_02947 1.1e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLNPHKMC_02948 2.9e-282 yfkQ EG Spore germination protein
MLNPHKMC_02949 2.5e-206 yfkR S spore germination
MLNPHKMC_02951 8.6e-193 E Spore germination protein
MLNPHKMC_02952 2.8e-252 agcS_1 E Sodium alanine symporter
MLNPHKMC_02953 6e-67 yhdN S Domain of unknown function (DUF1992)
MLNPHKMC_02954 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLNPHKMC_02955 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MLNPHKMC_02956 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
MLNPHKMC_02957 9.1e-50 yflH S Protein of unknown function (DUF3243)
MLNPHKMC_02958 4.1e-19 yflI
MLNPHKMC_02959 8.9e-18 yflJ S Protein of unknown function (DUF2639)
MLNPHKMC_02960 1.4e-121 yflK S protein conserved in bacteria
MLNPHKMC_02961 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MLNPHKMC_02962 1.8e-214 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MLNPHKMC_02963 1.1e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MLNPHKMC_02964 8.5e-227 citM C Citrate transporter
MLNPHKMC_02965 7.5e-180 yflP S Tripartite tricarboxylate transporter family receptor
MLNPHKMC_02966 2.9e-117 citT T response regulator
MLNPHKMC_02967 4.4e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MLNPHKMC_02968 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
MLNPHKMC_02969 1.4e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
MLNPHKMC_02970 7.6e-58 yflT S Heat induced stress protein YflT
MLNPHKMC_02971 2.6e-24 S Protein of unknown function (DUF3212)
MLNPHKMC_02972 1.8e-165 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MLNPHKMC_02973 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLNPHKMC_02974 2.8e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLNPHKMC_02975 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
MLNPHKMC_02976 4.8e-185 yfmJ S N-terminal domain of oxidoreductase
MLNPHKMC_02977 1.4e-75 yfmK 2.3.1.128 K acetyltransferase
MLNPHKMC_02978 7.7e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MLNPHKMC_02979 3.5e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLNPHKMC_02980 6.3e-57
MLNPHKMC_02982 6.4e-19
MLNPHKMC_02983 1.6e-59 isp O Subtilase family
MLNPHKMC_02984 6.2e-208 yfmO EGP Major facilitator Superfamily
MLNPHKMC_02985 1.4e-69 yfmP K transcriptional
MLNPHKMC_02986 2.8e-73 yfmQ S Uncharacterised protein from bacillus cereus group
MLNPHKMC_02987 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLNPHKMC_02988 1.1e-113 yfmS NT chemotaxis protein
MLNPHKMC_02989 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLNPHKMC_02990 1.1e-240 yfnA E amino acid
MLNPHKMC_02991 3.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MLNPHKMC_02992 1.3e-205 fsr P COG0477 Permeases of the major facilitator superfamily
MLNPHKMC_02993 1.5e-188 yfnD M Nucleotide-diphospho-sugar transferase
MLNPHKMC_02994 1.2e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
MLNPHKMC_02995 1e-178 yfnF M Nucleotide-diphospho-sugar transferase
MLNPHKMC_02996 1.6e-171 yfnG 4.2.1.45 M dehydratase
MLNPHKMC_02997 3e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
MLNPHKMC_02998 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLNPHKMC_02999 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MLNPHKMC_03000 3.6e-199 yetN S Protein of unknown function (DUF3900)
MLNPHKMC_03001 5.2e-209 yetM CH FAD binding domain
MLNPHKMC_03002 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
MLNPHKMC_03003 7e-151 yetK EG EamA-like transporter family
MLNPHKMC_03004 2.9e-145 1.1.1.136, 1.1.1.336 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLNPHKMC_03005 1.2e-41 J B3 4 domain protein
MLNPHKMC_03006 7.8e-33 S inositol 2-dehydrogenase activity
MLNPHKMC_03007 1.7e-96 gal 1.1.1.376, 1.1.1.48 S inositol 2-dehydrogenase activity
MLNPHKMC_03008 7.2e-102 C Belongs to the LDH2 MDH2 oxidoreductase family
MLNPHKMC_03009 4.8e-105 3.5.1.16 E succinyl-diaminopimelate desuccinylase activity
MLNPHKMC_03010 5.9e-75 G Xylose isomerase-like TIM barrel
MLNPHKMC_03011 1.1e-113 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MLNPHKMC_03012 1.5e-113 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MLNPHKMC_03013 8e-71 S inositol 2-dehydrogenase activity
MLNPHKMC_03014 3.2e-49 trpF 5.3.1.24 F Belongs to the TrpF family
MLNPHKMC_03015 1.7e-68 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MLNPHKMC_03016 7.7e-150 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MLNPHKMC_03017 2.9e-73 trpC 4.1.1.48 E Belongs to the TrpC family
MLNPHKMC_03018 6.5e-68 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MLNPHKMC_03019 1.3e-124 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLNPHKMC_03020 5.3e-105 yetJ S Belongs to the BI1 family
MLNPHKMC_03021 5.8e-19 yezD S Uncharacterized small protein (DUF2292)
MLNPHKMC_03022 1.9e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLNPHKMC_03023 2.6e-34
MLNPHKMC_03024 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLNPHKMC_03025 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MLNPHKMC_03026 5.2e-122 yetF S membrane
MLNPHKMC_03027 5.4e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MLNPHKMC_03028 3.8e-162 lplC G Binding-protein-dependent transport system inner membrane component
MLNPHKMC_03029 5.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MLNPHKMC_03030 4e-289 lplA G Bacterial extracellular solute-binding protein
MLNPHKMC_03031 0.0 yetA
MLNPHKMC_03032 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
MLNPHKMC_03033 2.6e-123 yesY E GDSL-like Lipase/Acylhydrolase
MLNPHKMC_03034 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MLNPHKMC_03035 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MLNPHKMC_03036 2.6e-112 yesV S Protein of unknown function, DUF624
MLNPHKMC_03037 2.3e-127 yesU S Domain of unknown function (DUF1961)
MLNPHKMC_03038 7e-127 E GDSL-like Lipase/Acylhydrolase
MLNPHKMC_03039 0.0 yesS K Transcriptional regulator
MLNPHKMC_03040 1.9e-197 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
MLNPHKMC_03041 3.5e-163 yesQ P Binding-protein-dependent transport system inner membrane component
MLNPHKMC_03042 2.3e-170 yesP G Binding-protein-dependent transport system inner membrane component
MLNPHKMC_03043 1.7e-243 yesO G Bacterial extracellular solute-binding protein
MLNPHKMC_03044 1.4e-201 yesN K helix_turn_helix, arabinose operon control protein
MLNPHKMC_03045 0.0 yesM 2.7.13.3 T Histidine kinase
MLNPHKMC_03046 3.4e-101 yesL S Protein of unknown function, DUF624
MLNPHKMC_03048 3e-101 yesJ K Acetyltransferase (GNAT) family
MLNPHKMC_03049 5.2e-104 cotJC P Spore Coat
MLNPHKMC_03050 1.5e-45 cotJB S CotJB protein
MLNPHKMC_03051 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
MLNPHKMC_03052 1.4e-150 yesF GM NAD(P)H-binding
MLNPHKMC_03053 9.7e-82 yesE S SnoaL-like domain
MLNPHKMC_03054 8e-100 dhaR3 K Transcriptional regulator
MLNPHKMC_03056 2.7e-126 yeeN K transcriptional regulatory protein
MLNPHKMC_03058 5.1e-212 S Tetratricopeptide repeat
MLNPHKMC_03059 3.9e-163 3.4.24.40 CO amine dehydrogenase activity
MLNPHKMC_03060 2.2e-96 L endonuclease activity
MLNPHKMC_03062 0.0 L nucleic acid phosphodiester bond hydrolysis
MLNPHKMC_03063 1.3e-55 S Protein of unknown function, DUF600
MLNPHKMC_03064 4.9e-37 S Protein of unknown function, DUF600
MLNPHKMC_03065 8e-35
MLNPHKMC_03066 2.7e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLNPHKMC_03067 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLNPHKMC_03068 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLNPHKMC_03069 3.4e-144 yerO K Transcriptional regulator
MLNPHKMC_03070 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLNPHKMC_03071 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MLNPHKMC_03072 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLNPHKMC_03073 1.2e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLNPHKMC_03074 1.6e-123 sapB S MgtC SapB transporter
MLNPHKMC_03075 3e-195 yerI S homoserine kinase type II (protein kinase fold)
MLNPHKMC_03076 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
MLNPHKMC_03077 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MLNPHKMC_03078 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MLNPHKMC_03079 1.9e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MLNPHKMC_03081 5.2e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
MLNPHKMC_03082 4.8e-51 yerC S protein conserved in bacteria
MLNPHKMC_03083 1.4e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
MLNPHKMC_03084 0.0 yerA 3.5.4.2 F adenine deaminase
MLNPHKMC_03085 4.6e-27 S Protein of unknown function (DUF2892)
MLNPHKMC_03086 4.1e-226 yjeH E Amino acid permease
MLNPHKMC_03087 4.3e-71 K helix_turn_helix ASNC type
MLNPHKMC_03088 3.8e-232 purD 6.3.4.13 F Belongs to the GARS family
MLNPHKMC_03089 1.7e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MLNPHKMC_03090 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MLNPHKMC_03091 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MLNPHKMC_03092 4.7e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLNPHKMC_03093 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLNPHKMC_03094 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLNPHKMC_03095 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLNPHKMC_03096 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MLNPHKMC_03097 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLNPHKMC_03098 3.3e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MLNPHKMC_03099 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MLNPHKMC_03100 8e-28 yebG S NETI protein
MLNPHKMC_03101 4e-93 yebE S UPF0316 protein
MLNPHKMC_03103 2.3e-118 yebC M Membrane
MLNPHKMC_03104 2.3e-211 pbuG S permease
MLNPHKMC_03105 4.8e-255 S Domain of unknown function (DUF4179)
MLNPHKMC_03106 1.5e-84 K Belongs to the sigma-70 factor family. ECF subfamily
MLNPHKMC_03107 4.9e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MLNPHKMC_03108 0.0 yebA E COG1305 Transglutaminase-like enzymes
MLNPHKMC_03109 1.5e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MLNPHKMC_03110 2.7e-177 yeaC S COG0714 MoxR-like ATPases
MLNPHKMC_03111 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLNPHKMC_03112 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
MLNPHKMC_03113 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MLNPHKMC_03114 1.3e-174 yeaA S Protein of unknown function (DUF4003)
MLNPHKMC_03115 3.8e-156 ydjP I Alpha/beta hydrolase family
MLNPHKMC_03116 1.4e-34 ydjO S Cold-inducible protein YdjO
MLNPHKMC_03118 7.2e-152 ydjN U Involved in the tonB-independent uptake of proteins
MLNPHKMC_03119 4.5e-64 ydjM M Lytic transglycolase
MLNPHKMC_03120 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MLNPHKMC_03121 2.3e-257 iolT EGP Major facilitator Superfamily
MLNPHKMC_03122 5.7e-194 S Ion transport 2 domain protein
MLNPHKMC_03123 2.6e-148 ydjI S virion core protein (lumpy skin disease virus)
MLNPHKMC_03124 5.5e-133 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
MLNPHKMC_03125 8.3e-177 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLNPHKMC_03126 2.5e-113 pspA KT Phage shock protein A
MLNPHKMC_03127 3.6e-174 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
MLNPHKMC_03128 7.4e-253 gutA G MFS/sugar transport protein
MLNPHKMC_03129 8.5e-201 gutB 1.1.1.14 E Dehydrogenase
MLNPHKMC_03130 0.0 K NB-ARC domain
MLNPHKMC_03131 2.9e-150 ydjC S Abhydrolase domain containing 18
MLNPHKMC_03132 3.7e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MLNPHKMC_03133 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MLNPHKMC_03134 7.9e-129 ydiL S CAAX protease self-immunity
MLNPHKMC_03135 2.9e-27 ydiK S Domain of unknown function (DUF4305)
MLNPHKMC_03136 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLNPHKMC_03137 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLNPHKMC_03138 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MLNPHKMC_03139 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MLNPHKMC_03140 0.0 ydiF S ABC transporter
MLNPHKMC_03141 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MLNPHKMC_03142 4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MLNPHKMC_03143 3.8e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MLNPHKMC_03144 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MLNPHKMC_03145 1.3e-176 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MLNPHKMC_03147 7.8e-08
MLNPHKMC_03148 3.4e-39 S COG NOG14552 non supervised orthologous group
MLNPHKMC_03151 2.3e-156 ydhU P Catalase
MLNPHKMC_03152 3.8e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MLNPHKMC_03153 1.6e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
MLNPHKMC_03154 2.6e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MLNPHKMC_03155 1.1e-132 ydhQ K UTRA
MLNPHKMC_03156 9e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLNPHKMC_03157 1.4e-232 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLNPHKMC_03158 9.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
MLNPHKMC_03159 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MLNPHKMC_03160 4.6e-200 pbuE EGP Major facilitator Superfamily
MLNPHKMC_03161 2.3e-96 ydhK M Protein of unknown function (DUF1541)
MLNPHKMC_03162 2.4e-181 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MLNPHKMC_03163 9.5e-83 K Acetyltransferase (GNAT) domain
MLNPHKMC_03165 1.6e-66 frataxin S Domain of unknown function (DU1801)
MLNPHKMC_03166 3.4e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MLNPHKMC_03167 1.6e-123
MLNPHKMC_03168 1.6e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLNPHKMC_03169 2.2e-243 ydhD M Glycosyl hydrolase
MLNPHKMC_03170 3.2e-121 ydhC K FCD
MLNPHKMC_03171 3.5e-121 ydhB S membrane transporter protein
MLNPHKMC_03172 6.3e-208 tcaB EGP Major facilitator Superfamily
MLNPHKMC_03173 7.1e-69 ydgJ K Winged helix DNA-binding domain
MLNPHKMC_03174 1e-113 drgA C nitroreductase
MLNPHKMC_03175 0.0 ydgH S drug exporters of the RND superfamily
MLNPHKMC_03176 2.3e-78 K helix_turn_helix multiple antibiotic resistance protein
MLNPHKMC_03177 1.2e-88 dinB S DinB family
MLNPHKMC_03178 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MLNPHKMC_03179 9.8e-305 expZ S ABC transporter
MLNPHKMC_03180 1.9e-83 yycN 2.3.1.128 K Acetyltransferase
MLNPHKMC_03181 4e-51 S DoxX-like family
MLNPHKMC_03182 2.3e-94 K Bacterial regulatory proteins, tetR family
MLNPHKMC_03183 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
MLNPHKMC_03184 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
MLNPHKMC_03185 8.5e-75 cotP O Belongs to the small heat shock protein (HSP20) family
MLNPHKMC_03186 1.5e-121 ydfS S Protein of unknown function (DUF421)
MLNPHKMC_03187 7.8e-115 ydfR S Protein of unknown function (DUF421)
MLNPHKMC_03189 6.3e-29
MLNPHKMC_03190 1.9e-15 ydgA S Spore germination protein gerPA/gerPF
MLNPHKMC_03191 6.3e-57 traF CO Thioredoxin
MLNPHKMC_03192 8.8e-63 mhqP S DoxX
MLNPHKMC_03193 6.2e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
MLNPHKMC_03194 1.2e-109 ydfN C nitroreductase
MLNPHKMC_03195 6.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLNPHKMC_03196 3.6e-144 K Bacterial transcription activator, effector binding domain
MLNPHKMC_03197 8.5e-117 S Protein of unknown function (DUF554)
MLNPHKMC_03198 5.2e-175 S Alpha/beta hydrolase family
MLNPHKMC_03199 0.0 ydfJ S drug exporters of the RND superfamily
MLNPHKMC_03200 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLNPHKMC_03201 1.9e-177 ydfH 2.7.13.3 T Histidine kinase
MLNPHKMC_03203 1.9e-77 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MLNPHKMC_03204 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
MLNPHKMC_03205 1.3e-116 ydfE S Flavin reductase like domain
MLNPHKMC_03206 4.6e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLNPHKMC_03207 2.2e-149 ydfC EG EamA-like transporter family
MLNPHKMC_03208 2.6e-122 T Transcriptional regulatory protein, C terminal
MLNPHKMC_03209 3.3e-211 T GHKL domain
MLNPHKMC_03210 2.8e-157
MLNPHKMC_03211 7e-123 nodB1 G deacetylase
MLNPHKMC_03212 2.4e-148 lytR K Transcriptional regulator
MLNPHKMC_03213 6e-143 ydfB J GNAT acetyltransferase
MLNPHKMC_03214 5.7e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLNPHKMC_03215 2.4e-56 arsR K transcriptional
MLNPHKMC_03216 1.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MLNPHKMC_03217 2e-55 K HxlR-like helix-turn-helix
MLNPHKMC_03218 6.2e-105 ydeN S Serine hydrolase
MLNPHKMC_03219 1.2e-52 maoC I N-terminal half of MaoC dehydratase
MLNPHKMC_03221 4.3e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLNPHKMC_03222 1e-151 ydeK EG -transporter
MLNPHKMC_03223 3e-111
MLNPHKMC_03224 2.1e-103 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
MLNPHKMC_03225 2.1e-45 ydeH
MLNPHKMC_03226 2.4e-218 ydeG EGP Major facilitator superfamily
MLNPHKMC_03227 1.7e-257 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLNPHKMC_03228 1.2e-165 ydeE K AraC family transcriptional regulator
MLNPHKMC_03229 2.2e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLNPHKMC_03230 3.4e-163 rhaS5 K AraC-like ligand binding domain
MLNPHKMC_03231 1.2e-139 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLNPHKMC_03232 6.8e-78 carD K Transcription factor
MLNPHKMC_03233 8.7e-30 cspL K Cold shock
MLNPHKMC_03234 6e-111 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MLNPHKMC_03238 2.7e-13
MLNPHKMC_03239 1.5e-138 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLNPHKMC_03240 1.6e-43
MLNPHKMC_03241 2.6e-32 S SMI1-KNR4 cell-wall
MLNPHKMC_03242 2.5e-226 ydeG EGP Major facilitator Superfamily
MLNPHKMC_03243 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
MLNPHKMC_03244 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
MLNPHKMC_03245 1.5e-77 lrpB K transcriptional
MLNPHKMC_03246 2.4e-71 lrpA K transcriptional
MLNPHKMC_03247 1e-187 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLNPHKMC_03255 8.9e-83 ydcK S Belongs to the SprT family
MLNPHKMC_03256 0.0 yhgF K COG2183 Transcriptional accessory protein
MLNPHKMC_03257 6.1e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
MLNPHKMC_03258 1.5e-82 ydcG S EVE domain
MLNPHKMC_03262 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MLNPHKMC_03263 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLNPHKMC_03264 6e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MLNPHKMC_03265 1.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
MLNPHKMC_03266 3.5e-188 rsbU 3.1.3.3 KT phosphatase
MLNPHKMC_03267 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MLNPHKMC_03268 5.2e-57 rsbS T antagonist
MLNPHKMC_03269 1.3e-143 rsbR T Positive regulator of sigma-B
MLNPHKMC_03270 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MLNPHKMC_03271 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MLNPHKMC_03272 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLNPHKMC_03273 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MLNPHKMC_03274 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MLNPHKMC_03275 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MLNPHKMC_03276 3e-260 ydbT S Membrane
MLNPHKMC_03277 2.1e-82 ydbS S Bacterial PH domain
MLNPHKMC_03278 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MLNPHKMC_03279 2.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MLNPHKMC_03280 1.1e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MLNPHKMC_03281 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MLNPHKMC_03282 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLNPHKMC_03283 2.2e-07 S Fur-regulated basic protein A
MLNPHKMC_03284 1.1e-18 S Fur-regulated basic protein B
MLNPHKMC_03285 1.3e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MLNPHKMC_03286 2.7e-52 ydbL
MLNPHKMC_03287 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLNPHKMC_03288 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
MLNPHKMC_03289 9.7e-181 ydbI S AI-2E family transporter
MLNPHKMC_03290 1.2e-225 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLNPHKMC_03291 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
MLNPHKMC_03292 1.2e-294 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MLNPHKMC_03293 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MLNPHKMC_03294 7.9e-154 ydbD P Catalase
MLNPHKMC_03295 6.9e-62 ydbC S Domain of unknown function (DUF4937
MLNPHKMC_03296 1.5e-55 ydbB G Cupin domain
MLNPHKMC_03298 1.2e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
MLNPHKMC_03299 3.6e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
MLNPHKMC_03301 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
MLNPHKMC_03302 2.1e-39
MLNPHKMC_03303 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MLNPHKMC_03304 3.3e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MLNPHKMC_03305 0.0 ydaO E amino acid
MLNPHKMC_03306 0.0 ydaN S Bacterial cellulose synthase subunit
MLNPHKMC_03307 1.3e-232 ydaM M Glycosyl transferase family group 2
MLNPHKMC_03308 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MLNPHKMC_03309 4.2e-150 ydaK T Diguanylate cyclase, GGDEF domain
MLNPHKMC_03310 4.2e-203 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
MLNPHKMC_03311 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLNPHKMC_03312 2.5e-74 lrpC K Transcriptional regulator
MLNPHKMC_03313 2.5e-46 ydzA EGP Major facilitator Superfamily
MLNPHKMC_03314 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MLNPHKMC_03315 1.2e-76 ydaG 1.4.3.5 S general stress protein
MLNPHKMC_03316 5.6e-103 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLNPHKMC_03317 1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
MLNPHKMC_03318 3.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLNPHKMC_03319 2.3e-94 ydaC Q Methyltransferase domain
MLNPHKMC_03320 3e-292 ydaB IQ acyl-CoA ligase
MLNPHKMC_03321 0.0 mtlR K transcriptional regulator, MtlR
MLNPHKMC_03322 1.7e-173 ydhF S Oxidoreductase
MLNPHKMC_03323 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MLNPHKMC_03324 1.4e-49 yczJ S biosynthesis
MLNPHKMC_03326 1.3e-119 ycsK E anatomical structure formation involved in morphogenesis
MLNPHKMC_03327 2.7e-132 kipR K Transcriptional regulator
MLNPHKMC_03328 5.6e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MLNPHKMC_03329 3.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MLNPHKMC_03330 2.1e-148 ycsI S Belongs to the D-glutamate cyclase family
MLNPHKMC_03331 8.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MLNPHKMC_03332 1.2e-138 ycsF S Belongs to the UPF0271 (lamB) family
MLNPHKMC_03333 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MLNPHKMC_03335 2.3e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MLNPHKMC_03336 9.1e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
MLNPHKMC_03337 7.9e-73 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLNPHKMC_03338 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLNPHKMC_03339 7.2e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MLNPHKMC_03340 1.3e-210 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MLNPHKMC_03341 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MLNPHKMC_03342 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MLNPHKMC_03343 3.4e-53
MLNPHKMC_03344 2.8e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
MLNPHKMC_03345 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
MLNPHKMC_03346 1.4e-99 ycnI S protein conserved in bacteria
MLNPHKMC_03347 6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLNPHKMC_03348 6.1e-149 glcU U Glucose uptake
MLNPHKMC_03349 2.2e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLNPHKMC_03350 4.8e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLNPHKMC_03351 6.6e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLNPHKMC_03352 1.1e-50 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
MLNPHKMC_03353 1.6e-45 ycnE S Monooxygenase
MLNPHKMC_03354 9.8e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
MLNPHKMC_03355 5.5e-153 ycnC K Transcriptional regulator
MLNPHKMC_03356 9.2e-251 ycnB EGP Major facilitator Superfamily
MLNPHKMC_03357 2.1e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MLNPHKMC_03358 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MLNPHKMC_03359 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLNPHKMC_03360 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLNPHKMC_03361 8.8e-251 lysC 2.7.2.4 E Belongs to the aspartokinase family
MLNPHKMC_03364 2.6e-70 S aspartate phosphatase
MLNPHKMC_03365 9.8e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MLNPHKMC_03366 2.3e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLNPHKMC_03367 4e-201 yclI V ABC transporter (permease) YclI
MLNPHKMC_03368 5.6e-121 yclH P ABC transporter
MLNPHKMC_03369 2.4e-193 gerKB F Spore germination protein
MLNPHKMC_03370 2.8e-224 gerKC S spore germination
MLNPHKMC_03371 1.8e-279 gerKA EG Spore germination protein
MLNPHKMC_03373 1.1e-298 yclG M Pectate lyase superfamily protein
MLNPHKMC_03374 5.2e-265 dtpT E amino acid peptide transporter
MLNPHKMC_03375 2.4e-158 yclE 3.4.11.5 S Alpha beta hydrolase
MLNPHKMC_03376 3.5e-82 yclD
MLNPHKMC_03377 4e-39 bsdD 4.1.1.61 S response to toxic substance
MLNPHKMC_03378 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MLNPHKMC_03379 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MLNPHKMC_03380 1.9e-161 bsdA K LysR substrate binding domain
MLNPHKMC_03381 2e-125 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MLNPHKMC_03382 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
MLNPHKMC_03383 4.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLNPHKMC_03384 9.7e-115 yczE S membrane
MLNPHKMC_03385 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MLNPHKMC_03386 1.2e-252 ycxD K GntR family transcriptional regulator
MLNPHKMC_03387 2.9e-160 ycxC EG EamA-like transporter family
MLNPHKMC_03388 2.4e-85 S YcxB-like protein
MLNPHKMC_03389 3.8e-221 EGP Major Facilitator Superfamily
MLNPHKMC_03390 4.9e-139 srfAD Q thioesterase
MLNPHKMC_03391 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
MLNPHKMC_03392 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLNPHKMC_03393 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLNPHKMC_03394 1.3e-63 hxlR K transcriptional
MLNPHKMC_03395 9.5e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MLNPHKMC_03396 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
MLNPHKMC_03397 6.7e-179 tlpC 2.7.13.3 NT chemotaxis protein
MLNPHKMC_03398 1.7e-70 nucA M Deoxyribonuclease NucA/NucB
MLNPHKMC_03399 1.9e-68 nin S Competence protein J (ComJ)
MLNPHKMC_03400 2.8e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLNPHKMC_03401 2.7e-121 S AAA domain
MLNPHKMC_03402 9.3e-24
MLNPHKMC_03403 4.1e-45 K MarR family
MLNPHKMC_03404 1.1e-50 yckD S Protein of unknown function (DUF2680)
MLNPHKMC_03405 2e-74 yckC S membrane
MLNPHKMC_03407 4e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MLNPHKMC_03408 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
MLNPHKMC_03409 2e-227 yciC S GTPases (G3E family)
MLNPHKMC_03410 1e-107 yciB M ErfK YbiS YcfS YnhG
MLNPHKMC_03411 7.9e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
MLNPHKMC_03412 1.7e-221 nasA P COG2223 Nitrate nitrite transporter
MLNPHKMC_03413 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
MLNPHKMC_03414 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLNPHKMC_03415 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MLNPHKMC_03416 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
MLNPHKMC_03417 4.9e-276 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MLNPHKMC_03418 4.6e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MLNPHKMC_03419 3.2e-158 I alpha/beta hydrolase fold
MLNPHKMC_03420 1.2e-139 ycgR S permeases
MLNPHKMC_03421 7.5e-147 ycgQ S membrane
MLNPHKMC_03422 1.8e-100 V ATPases associated with a variety of cellular activities
MLNPHKMC_03423 0.0 S Protein of unknown function (DUF1430)
MLNPHKMC_03425 2.3e-226 ycgP QT COG2508 Regulator of polyketide synthase expression
MLNPHKMC_03426 4.4e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLNPHKMC_03427 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLNPHKMC_03428 5.1e-170 ycgM E Proline dehydrogenase
MLNPHKMC_03429 2.7e-143 ycgL S Predicted nucleotidyltransferase
MLNPHKMC_03430 4.2e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MLNPHKMC_03431 5.1e-176 oxyR3 K LysR substrate binding domain
MLNPHKMC_03432 6.9e-144 yafE Q ubiE/COQ5 methyltransferase family
MLNPHKMC_03433 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MLNPHKMC_03434 1.8e-107 tmrB S AAA domain
MLNPHKMC_03435 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MLNPHKMC_03436 2.4e-112 ycgI S Domain of unknown function (DUF1989)
MLNPHKMC_03437 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MLNPHKMC_03438 9.9e-151 yqcI S YqcI/YcgG family
MLNPHKMC_03439 6.8e-113 ycgF E Lysine exporter protein LysE YggA
MLNPHKMC_03440 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
MLNPHKMC_03441 2.5e-262 mdr EGP Major facilitator Superfamily
MLNPHKMC_03442 2.7e-291 lctP C L-lactate permease
MLNPHKMC_03443 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MLNPHKMC_03444 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
MLNPHKMC_03445 4.1e-81 ycgB
MLNPHKMC_03446 3.3e-256 ycgA S Membrane
MLNPHKMC_03447 1.1e-214 amhX S amidohydrolase
MLNPHKMC_03448 5.3e-164 opuAC E glycine betaine
MLNPHKMC_03449 1.3e-127 opuAB P glycine betaine
MLNPHKMC_03450 5.1e-229 proV 3.6.3.32 E glycine betaine
MLNPHKMC_03451 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
MLNPHKMC_03452 1.2e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
MLNPHKMC_03453 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
MLNPHKMC_03454 2e-192 yceH P Belongs to the TelA family
MLNPHKMC_03455 0.0 yceG S Putative component of 'biosynthetic module'
MLNPHKMC_03456 6.3e-137 terC P Protein of unknown function (DUF475)
MLNPHKMC_03457 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
MLNPHKMC_03458 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
MLNPHKMC_03459 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
MLNPHKMC_03460 1.4e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLNPHKMC_03461 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MLNPHKMC_03462 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MLNPHKMC_03463 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
MLNPHKMC_03464 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
MLNPHKMC_03465 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
MLNPHKMC_03466 6.1e-173 S response regulator aspartate phosphatase
MLNPHKMC_03467 1.3e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
MLNPHKMC_03468 2.4e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
MLNPHKMC_03469 5.9e-274 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
MLNPHKMC_03470 6.6e-177 ycdA S Domain of unknown function (DUF5105)
MLNPHKMC_03471 2.3e-173 yccK C Aldo keto reductase
MLNPHKMC_03472 1.3e-199 natB CP ABC-2 family transporter protein
MLNPHKMC_03473 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
MLNPHKMC_03474 1.2e-126 lytR_2 T LytTr DNA-binding domain
MLNPHKMC_03475 2.4e-154 2.7.13.3 T GHKL domain
MLNPHKMC_03476 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
MLNPHKMC_03477 7.1e-57 S RDD family
MLNPHKMC_03478 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MLNPHKMC_03479 2e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MLNPHKMC_03480 5.9e-100 yxaF K Transcriptional regulator
MLNPHKMC_03481 7.6e-229 lmrB EGP the major facilitator superfamily
MLNPHKMC_03482 7.8e-205 ycbU E Selenocysteine lyase
MLNPHKMC_03483 1.7e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MLNPHKMC_03484 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLNPHKMC_03485 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLNPHKMC_03486 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
MLNPHKMC_03487 2.5e-135 ycbR T vWA found in TerF C terminus
MLNPHKMC_03488 2.2e-78 sleB 3.5.1.28 M Cell wall
MLNPHKMC_03489 8.2e-53 ycbP S Protein of unknown function (DUF2512)
MLNPHKMC_03490 2.5e-113 S ABC-2 family transporter protein
MLNPHKMC_03491 1.3e-165 ycbN V ABC transporter, ATP-binding protein
MLNPHKMC_03492 1.3e-168 T PhoQ Sensor
MLNPHKMC_03493 1.2e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLNPHKMC_03494 1.2e-166 eamA1 EG spore germination
MLNPHKMC_03495 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
MLNPHKMC_03496 2.2e-176 ycbJ S Macrolide 2'-phosphotransferase
MLNPHKMC_03497 1.7e-295 garD 4.2.1.42, 4.2.1.7 G Altronate
MLNPHKMC_03498 1.5e-124 ycbG K FCD
MLNPHKMC_03499 5.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MLNPHKMC_03500 7.7e-255 gudP G COG0477 Permeases of the major facilitator superfamily
MLNPHKMC_03501 1.2e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLNPHKMC_03502 1e-173 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
MLNPHKMC_03503 1e-168 glnL T Regulator
MLNPHKMC_03504 9.4e-229 phoQ 2.7.13.3 T Histidine kinase
MLNPHKMC_03505 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
MLNPHKMC_03506 7.3e-256 agcS E Sodium alanine symporter
MLNPHKMC_03508 6.7e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
MLNPHKMC_03509 6.7e-262 mmuP E amino acid
MLNPHKMC_03510 5.1e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MLNPHKMC_03512 4.9e-128 K UTRA
MLNPHKMC_03513 8e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLNPHKMC_03514 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLNPHKMC_03515 1.4e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLNPHKMC_03516 5.6e-191 yceA S Belongs to the UPF0176 family
MLNPHKMC_03517 2.3e-44 ybfN
MLNPHKMC_03518 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MLNPHKMC_03519 2.7e-85 ybfM S SNARE associated Golgi protein
MLNPHKMC_03520 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLNPHKMC_03521 8e-168 S Alpha/beta hydrolase family
MLNPHKMC_03523 9.9e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
MLNPHKMC_03524 8.9e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MLNPHKMC_03525 3e-145 msmR K AraC-like ligand binding domain
MLNPHKMC_03526 4.4e-161 ybfH EG EamA-like transporter family
MLNPHKMC_03528 1.8e-221 ybfB G COG0477 Permeases of the major facilitator superfamily
MLNPHKMC_03529 3.3e-169 ybfA 3.4.15.5 K FR47-like protein
MLNPHKMC_03530 1.5e-34 S Protein of unknown function (DUF2651)
MLNPHKMC_03531 7.3e-258 glpT G -transporter
MLNPHKMC_03532 8.2e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MLNPHKMC_03533 6.8e-290 ybeC E amino acid
MLNPHKMC_03534 4.9e-41 ybyB
MLNPHKMC_03535 3.9e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MLNPHKMC_03536 2.6e-149 ybxI 3.5.2.6 V beta-lactamase
MLNPHKMC_03537 4.9e-30 ybxH S Family of unknown function (DUF5370)
MLNPHKMC_03538 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
MLNPHKMC_03539 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MLNPHKMC_03540 1.5e-214 ybdO S Domain of unknown function (DUF4885)
MLNPHKMC_03541 2.5e-150 ybdN
MLNPHKMC_03542 5.7e-138 KLT Protein tyrosine kinase
MLNPHKMC_03544 4.9e-57
MLNPHKMC_03545 9e-69 ybcL EGP Major facilitator Superfamily
MLNPHKMC_03546 6.1e-115 ybcL EGP Major facilitator Superfamily
MLNPHKMC_03547 5.1e-50 ybzH K Helix-turn-helix domain
MLNPHKMC_03548 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
MLNPHKMC_03549 1.1e-46
MLNPHKMC_03551 8.6e-93 can 4.2.1.1 P carbonic anhydrase
MLNPHKMC_03552 0.0 ybcC S Belongs to the UPF0753 family
MLNPHKMC_03553 1.6e-272 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MLNPHKMC_03554 2.6e-97 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLNPHKMC_03555 3.2e-118 adaA 3.2.2.21 K Transcriptional regulator
MLNPHKMC_03556 9.3e-172 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MLNPHKMC_03557 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MLNPHKMC_03558 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLNPHKMC_03559 1.5e-224 ybbR S protein conserved in bacteria
MLNPHKMC_03560 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLNPHKMC_03561 4.8e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MLNPHKMC_03562 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MLNPHKMC_03568 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
MLNPHKMC_03569 9.2e-86 ybbJ J acetyltransferase
MLNPHKMC_03570 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MLNPHKMC_03571 1.4e-150 ybbH K transcriptional
MLNPHKMC_03572 1.3e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLNPHKMC_03573 4.5e-252 yfeW 3.4.16.4 V Belongs to the UPF0214 family
MLNPHKMC_03574 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MLNPHKMC_03575 9.2e-239 ybbC 3.2.1.52 S protein conserved in bacteria
MLNPHKMC_03576 1.2e-288 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
MLNPHKMC_03577 7e-154 feuA P Iron-uptake system-binding protein
MLNPHKMC_03578 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLNPHKMC_03579 5.1e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLNPHKMC_03580 1.6e-132 ybbA S Putative esterase
MLNPHKMC_03581 1.6e-161 ybaS 1.1.1.58 S Na -dependent transporter
MLNPHKMC_03583 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
MLNPHKMC_03584 3.4e-39 S COG NOG14552 non supervised orthologous group
MLNPHKMC_03588 2e-08
MLNPHKMC_03591 3.4e-39 S COG NOG14552 non supervised orthologous group
MLNPHKMC_03592 3.4e-39 S COG NOG14552 non supervised orthologous group
MLNPHKMC_03593 1e-139 pdaB 3.5.1.104 G Polysaccharide deacetylase
MLNPHKMC_03594 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MLNPHKMC_03595 1.2e-84 gerD
MLNPHKMC_03596 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MLNPHKMC_03597 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLNPHKMC_03598 9.7e-66 ybaK S Protein of unknown function (DUF2521)
MLNPHKMC_03599 3.4e-143 ybaJ Q Methyltransferase domain
MLNPHKMC_03600 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MLNPHKMC_03601 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MLNPHKMC_03602 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MLNPHKMC_03603 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLNPHKMC_03604 1.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLNPHKMC_03605 1.6e-154 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLNPHKMC_03606 3.6e-58 rplQ J Ribosomal protein L17
MLNPHKMC_03607 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLNPHKMC_03608 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MLNPHKMC_03609 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MLNPHKMC_03610 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MLNPHKMC_03611 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MLNPHKMC_03612 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
MLNPHKMC_03613 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MLNPHKMC_03614 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MLNPHKMC_03615 1.8e-72 rplO J binds to the 23S rRNA
MLNPHKMC_03616 1.9e-23 rpmD J Ribosomal protein L30
MLNPHKMC_03617 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MLNPHKMC_03618 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MLNPHKMC_03619 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MLNPHKMC_03620 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MLNPHKMC_03621 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLNPHKMC_03622 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MLNPHKMC_03623 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MLNPHKMC_03624 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MLNPHKMC_03625 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MLNPHKMC_03626 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MLNPHKMC_03627 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MLNPHKMC_03628 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MLNPHKMC_03629 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MLNPHKMC_03630 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MLNPHKMC_03631 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MLNPHKMC_03632 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MLNPHKMC_03633 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
MLNPHKMC_03634 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MLNPHKMC_03635 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MLNPHKMC_03636 1.2e-180 ybaC 3.4.11.5 S Alpha/beta hydrolase family
MLNPHKMC_03637 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MLNPHKMC_03638 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MLNPHKMC_03639 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MLNPHKMC_03640 2.5e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MLNPHKMC_03641 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
MLNPHKMC_03642 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLNPHKMC_03643 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLNPHKMC_03644 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
MLNPHKMC_03645 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MLNPHKMC_03646 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MLNPHKMC_03647 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MLNPHKMC_03648 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MLNPHKMC_03649 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
MLNPHKMC_03650 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MLNPHKMC_03651 4.4e-115 sigH K Belongs to the sigma-70 factor family
MLNPHKMC_03652 1.2e-88 yacP S RNA-binding protein containing a PIN domain
MLNPHKMC_03653 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLNPHKMC_03654 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MLNPHKMC_03655 2.1e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MLNPHKMC_03656 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
MLNPHKMC_03657 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MLNPHKMC_03658 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MLNPHKMC_03659 5.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MLNPHKMC_03660 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MLNPHKMC_03661 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MLNPHKMC_03662 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MLNPHKMC_03663 0.0 clpC O Belongs to the ClpA ClpB family
MLNPHKMC_03664 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MLNPHKMC_03665 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MLNPHKMC_03666 2.9e-76 ctsR K Belongs to the CtsR family
MLNPHKMC_03667 3.4e-39 S COG NOG14552 non supervised orthologous group
MLNPHKMC_03672 2e-08
MLNPHKMC_03677 3.4e-39 S COG NOG14552 non supervised orthologous group
MLNPHKMC_03678 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MLNPHKMC_03679 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLNPHKMC_03680 4.1e-30 yazB K transcriptional
MLNPHKMC_03681 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MLNPHKMC_03682 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MLNPHKMC_03683 5.9e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MLNPHKMC_03684 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
MLNPHKMC_03685 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MLNPHKMC_03686 9.1e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLNPHKMC_03687 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MLNPHKMC_03688 7.2e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
MLNPHKMC_03689 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MLNPHKMC_03690 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MLNPHKMC_03691 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MLNPHKMC_03692 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MLNPHKMC_03693 1.5e-269 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MLNPHKMC_03694 1.3e-185 KLT serine threonine protein kinase
MLNPHKMC_03695 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
MLNPHKMC_03696 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MLNPHKMC_03699 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MLNPHKMC_03700 1.1e-44 divIC D Septum formation initiator
MLNPHKMC_03701 9.5e-107 yabQ S spore cortex biosynthesis protein
MLNPHKMC_03702 1.5e-49 yabP S Sporulation protein YabP
MLNPHKMC_03703 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MLNPHKMC_03704 3.1e-241 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MLNPHKMC_03705 3.8e-285 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLNPHKMC_03706 1.5e-92 spoVT K stage V sporulation protein
MLNPHKMC_03707 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLNPHKMC_03708 2.4e-39 yabK S Peptide ABC transporter permease
MLNPHKMC_03709 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MLNPHKMC_03710 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MLNPHKMC_03711 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLNPHKMC_03712 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MLNPHKMC_03713 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MLNPHKMC_03714 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MLNPHKMC_03715 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MLNPHKMC_03716 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MLNPHKMC_03717 8.3e-27 sspF S DNA topological change
MLNPHKMC_03718 7.8e-39 veg S protein conserved in bacteria
MLNPHKMC_03719 1.6e-136 yabG S peptidase
MLNPHKMC_03720 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MLNPHKMC_03721 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MLNPHKMC_03722 7.6e-167 rpfB GH23 T protein conserved in bacteria
MLNPHKMC_03723 3.4e-143 tatD L hydrolase, TatD
MLNPHKMC_03724 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLNPHKMC_03725 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
MLNPHKMC_03726 6e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLNPHKMC_03727 2.1e-48 yazA L endonuclease containing a URI domain
MLNPHKMC_03728 1.2e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
MLNPHKMC_03729 4.8e-31 yabA L Involved in initiation control of chromosome replication
MLNPHKMC_03730 6.1e-146 yaaT S stage 0 sporulation protein
MLNPHKMC_03731 3.1e-181 holB 2.7.7.7 L DNA polymerase III
MLNPHKMC_03732 1.5e-71 yaaR S protein conserved in bacteria
MLNPHKMC_03733 2.2e-54 yaaQ S protein conserved in bacteria
MLNPHKMC_03734 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MLNPHKMC_03735 1.3e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MLNPHKMC_03736 9.9e-203 yaaN P Belongs to the TelA family
MLNPHKMC_03737 1.8e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MLNPHKMC_03738 1.7e-30 csfB S Inhibitor of sigma-G Gin
MLNPHKMC_03741 3.4e-39 S COG NOG14552 non supervised orthologous group
MLNPHKMC_03742 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
MLNPHKMC_03743 7.9e-32 yaaL S Protein of unknown function (DUF2508)
MLNPHKMC_03744 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MLNPHKMC_03745 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MLNPHKMC_03746 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLNPHKMC_03747 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MLNPHKMC_03748 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
MLNPHKMC_03749 1.2e-212 yaaH M Glycoside Hydrolase Family
MLNPHKMC_03750 7.9e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MLNPHKMC_03751 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MLNPHKMC_03752 1.3e-09
MLNPHKMC_03753 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLNPHKMC_03754 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MLNPHKMC_03755 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MLNPHKMC_03756 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MLNPHKMC_03757 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MLNPHKMC_03758 3.5e-180 yaaC S YaaC-like Protein
MLNPHKMC_03761 3.4e-39 S COG NOG14552 non supervised orthologous group
MLNPHKMC_03762 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLNPHKMC_03763 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLNPHKMC_03764 4e-37 yaaB S Domain of unknown function (DUF370)
MLNPHKMC_03765 1e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MLNPHKMC_03766 2.4e-33 yaaA S S4 domain
MLNPHKMC_03767 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MLNPHKMC_03768 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MLNPHKMC_03769 1.2e-53 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MLNPHKMC_03770 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLNPHKMC_03771 2.5e-107 jag S single-stranded nucleic acid binding R3H
MLNPHKMC_03772 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MLNPHKMC_03773 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MLNPHKMC_03774 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MLNPHKMC_03775 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MLNPHKMC_03776 1.5e-74 S Bacterial PH domain
MLNPHKMC_03777 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
MLNPHKMC_03778 2.1e-149 spo0J K Belongs to the ParB family
MLNPHKMC_03779 2.8e-111 yyaC S Sporulation protein YyaC
MLNPHKMC_03780 8.1e-177 yyaD S Membrane
MLNPHKMC_03781 2.3e-33 yyzM S protein conserved in bacteria
MLNPHKMC_03782 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLNPHKMC_03783 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MLNPHKMC_03784 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
MLNPHKMC_03785 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MLNPHKMC_03786 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MLNPHKMC_03787 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
MLNPHKMC_03788 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
MLNPHKMC_03789 1.5e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLNPHKMC_03790 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
MLNPHKMC_03791 2.7e-244 EGP Major facilitator superfamily
MLNPHKMC_03792 3.6e-168 yyaK S CAAX protease self-immunity
MLNPHKMC_03793 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MLNPHKMC_03794 1.7e-246 tetL EGP Major facilitator Superfamily
MLNPHKMC_03795 3.8e-107 yyaP 1.5.1.3 H RibD C-terminal domain
MLNPHKMC_03796 3.5e-66 yyaQ S YjbR
MLNPHKMC_03797 1.3e-93 yyaR K Acetyltransferase (GNAT) domain
MLNPHKMC_03798 8.5e-97 yyaS S Membrane
MLNPHKMC_03799 4.2e-69 yjcF S Acetyltransferase (GNAT) domain
MLNPHKMC_03800 5.6e-77 yybA 2.3.1.57 K transcriptional
MLNPHKMC_03801 3.6e-125 S Metallo-beta-lactamase superfamily
MLNPHKMC_03802 2.9e-66 yybH S SnoaL-like domain
MLNPHKMC_03803 8.7e-126
MLNPHKMC_03804 4.3e-111 K TipAS antibiotic-recognition domain
MLNPHKMC_03805 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
MLNPHKMC_03807 1.3e-70
MLNPHKMC_03808 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MLNPHKMC_03809 1.4e-68 ydeP3 K Transcriptional regulator
MLNPHKMC_03810 3.9e-84 cotF M Spore coat protein
MLNPHKMC_03812 2.9e-160 yybS S membrane
MLNPHKMC_03813 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MLNPHKMC_03814 2.2e-73 rplI J binds to the 23S rRNA
MLNPHKMC_03815 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLNPHKMC_03816 8.4e-221 yeaN P COG2807 Cyanate permease
MLNPHKMC_03817 1.9e-15 yycC K YycC-like protein
MLNPHKMC_03819 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
MLNPHKMC_03820 2e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MLNPHKMC_03821 1.7e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLNPHKMC_03822 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MLNPHKMC_03827 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLNPHKMC_03828 0.0 vicK 2.7.13.3 T Histidine kinase
MLNPHKMC_03829 5.2e-259 yycH S protein conserved in bacteria
MLNPHKMC_03830 7.3e-155 yycI S protein conserved in bacteria
MLNPHKMC_03831 5.7e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MLNPHKMC_03832 4.6e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLNPHKMC_03833 2.1e-255 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MLNPHKMC_03834 1.3e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MLNPHKMC_03835 4.8e-260 rocE E amino acid
MLNPHKMC_03836 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MLNPHKMC_03838 1.5e-187 S aspartate phosphatase
MLNPHKMC_03839 2.9e-84 yycN 2.3.1.128 K Acetyltransferase
MLNPHKMC_03840 6.4e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MLNPHKMC_03841 2.7e-208 yycP
MLNPHKMC_03842 1.1e-29 yycQ S Protein of unknown function (DUF2651)
MLNPHKMC_03844 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLNPHKMC_03845 1.9e-63
MLNPHKMC_03846 1.1e-09 S YyzF-like protein
MLNPHKMC_03847 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MLNPHKMC_03850 1.3e-126 2.7.7.49 L DNA polymerase
MLNPHKMC_03852 1.1e-153 L RNA-directed DNA polymerase
MLNPHKMC_03854 6.8e-42 S MazG-like family
MLNPHKMC_03855 7.9e-246 L Uncharacterized conserved protein (DUF2075)
MLNPHKMC_03856 0.0 L AAA domain
MLNPHKMC_03857 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
MLNPHKMC_03858 5.6e-11
MLNPHKMC_03859 1.6e-123 yydK K Transcriptional regulator
MLNPHKMC_03860 1.4e-31 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MLNPHKMC_03861 2e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLNPHKMC_03862 1.9e-286 ahpF O Alkyl hydroperoxide reductase
MLNPHKMC_03863 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MLNPHKMC_03864 2.5e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLNPHKMC_03865 8.5e-230 gntP EG COG2610 H gluconate symporter and related permeases
MLNPHKMC_03866 3.3e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MLNPHKMC_03867 8.1e-126 gntR K transcriptional
MLNPHKMC_03868 4e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MLNPHKMC_03869 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
MLNPHKMC_03870 5e-117 yxaC M effector of murein hydrolase
MLNPHKMC_03871 6.2e-48 S LrgA family
MLNPHKMC_03872 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
MLNPHKMC_03873 4.4e-197 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLNPHKMC_03874 1.5e-98 yxaF K Transcriptional regulator
MLNPHKMC_03875 3.5e-196 yxaG 1.13.11.24 S AraC-like ligand binding domain
MLNPHKMC_03876 9e-223 P Protein of unknown function (DUF418)
MLNPHKMC_03877 6.9e-75 yxaI S membrane protein domain
MLNPHKMC_03878 1.6e-62 S Family of unknown function (DUF5391)
MLNPHKMC_03879 1.3e-91 S PQQ-like domain
MLNPHKMC_03880 6.7e-33 yxaI S membrane protein domain
MLNPHKMC_03881 1.7e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MLNPHKMC_03882 2.7e-208 yxbF K Bacterial regulatory proteins, tetR family
MLNPHKMC_03883 1e-148 IQ Enoyl-(Acyl carrier protein) reductase
MLNPHKMC_03885 0.0 htpG O Molecular chaperone. Has ATPase activity
MLNPHKMC_03886 1.1e-245 csbC EGP Major facilitator Superfamily
MLNPHKMC_03887 1.1e-47 yxcD S Protein of unknown function (DUF2653)
MLNPHKMC_03889 7e-175 iolS C Aldo keto reductase
MLNPHKMC_03890 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
MLNPHKMC_03891 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLNPHKMC_03892 3.5e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MLNPHKMC_03893 2.1e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MLNPHKMC_03894 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MLNPHKMC_03895 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MLNPHKMC_03896 2.5e-234 iolF EGP Major facilitator Superfamily
MLNPHKMC_03897 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MLNPHKMC_03898 8.6e-167 iolH G Xylose isomerase-like TIM barrel
MLNPHKMC_03899 1.1e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MLNPHKMC_03900 3e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MLNPHKMC_03901 1.2e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLNPHKMC_03902 3.4e-180 T PhoQ Sensor
MLNPHKMC_03903 2.6e-138 yxdL V ABC transporter, ATP-binding protein
MLNPHKMC_03904 0.0 yxdM V ABC transporter (permease)
MLNPHKMC_03905 5.9e-58 yxeA S Protein of unknown function (DUF1093)
MLNPHKMC_03906 1.1e-175 fhuD P ABC transporter
MLNPHKMC_03907 1.4e-68
MLNPHKMC_03908 5.6e-16 yxeD
MLNPHKMC_03909 1.3e-20 yxeE
MLNPHKMC_03912 1.8e-150 yidA S hydrolases of the HAD superfamily
MLNPHKMC_03913 1.7e-187 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MLNPHKMC_03914 4.9e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLNPHKMC_03915 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLNPHKMC_03916 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
MLNPHKMC_03917 1.6e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
MLNPHKMC_03918 5.9e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
MLNPHKMC_03919 4e-212 yxeP 3.5.1.47 E hydrolase activity
MLNPHKMC_03920 1.6e-249 yxeQ S MmgE/PrpD family
MLNPHKMC_03921 2.1e-197 eutH E Ethanolamine utilisation protein, EutH
MLNPHKMC_03922 2e-152 yxxB S Domain of Unknown Function (DUF1206)
MLNPHKMC_03923 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLNPHKMC_03924 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MLNPHKMC_03925 1.7e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLNPHKMC_03926 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MLNPHKMC_03927 1.5e-250 lysP E amino acid
MLNPHKMC_03928 1.8e-178 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MLNPHKMC_03929 3.1e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
MLNPHKMC_03930 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MLNPHKMC_03931 6.8e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
MLNPHKMC_03932 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MLNPHKMC_03933 6.3e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MLNPHKMC_03934 5.9e-59 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MLNPHKMC_03936 0.0 L HKD family nuclease
MLNPHKMC_03937 2.3e-20 S Domain of unknown function (DUF5082)
MLNPHKMC_03938 1.4e-38 yxiC S Family of unknown function (DUF5344)
MLNPHKMC_03939 5.5e-138 S nuclease activity
MLNPHKMC_03940 3.3e-32
MLNPHKMC_03941 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLNPHKMC_03942 9.3e-280 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLNPHKMC_03943 5.4e-72 yxiE T Belongs to the universal stress protein A family
MLNPHKMC_03944 3.3e-164 yxxF EG EamA-like transporter family
MLNPHKMC_03945 0.0 wapA M COG3209 Rhs family protein
MLNPHKMC_03946 8.8e-07
MLNPHKMC_03947 1.1e-42 S Protein of unknown function (DUF2812)
MLNPHKMC_03948 4.2e-53 padR K Transcriptional regulator PadR-like family
MLNPHKMC_03949 3.6e-213 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
MLNPHKMC_03950 2.5e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MLNPHKMC_03951 1.1e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
MLNPHKMC_03952 2.1e-112
MLNPHKMC_03953 1.8e-150 licT K transcriptional antiterminator
MLNPHKMC_03954 6.1e-142 exoK GH16 M licheninase activity
MLNPHKMC_03955 6.6e-224 citH C Citrate transporter
MLNPHKMC_03956 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
MLNPHKMC_03957 1.6e-45 yxiS
MLNPHKMC_03958 6.1e-104 T Domain of unknown function (DUF4163)
MLNPHKMC_03959 1.2e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLNPHKMC_03960 2.5e-155 rlmA 2.1.1.187 Q Methyltransferase domain
MLNPHKMC_03961 1.4e-251 yxjC EG COG2610 H gluconate symporter and related permeases
MLNPHKMC_03962 4.5e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLNPHKMC_03963 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLNPHKMC_03964 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MLNPHKMC_03965 1.3e-218 yxjG 2.1.1.14 E Methionine synthase
MLNPHKMC_03966 4.3e-219 yxjG 2.1.1.14 E Methionine synthase
MLNPHKMC_03967 3.2e-86 yxjI S LURP-one-related
MLNPHKMC_03969 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MLNPHKMC_03970 1.2e-112 K helix_turn_helix, Lux Regulon
MLNPHKMC_03971 3.6e-179 yxjM T Signal transduction histidine kinase
MLNPHKMC_03972 5.9e-77 S Protein of unknown function (DUF1453)
MLNPHKMC_03973 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MLNPHKMC_03974 1.3e-74 yxkC S Domain of unknown function (DUF4352)
MLNPHKMC_03975 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLNPHKMC_03976 7.4e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLNPHKMC_03977 2.9e-162 lrp QT PucR C-terminal helix-turn-helix domain
MLNPHKMC_03978 1e-204 msmK P Belongs to the ABC transporter superfamily
MLNPHKMC_03979 8.8e-08 P transporter
MLNPHKMC_03982 5.6e-155 yxkH G Polysaccharide deacetylase
MLNPHKMC_03984 2.3e-311 3.4.24.84 O Peptidase family M48
MLNPHKMC_03985 2.3e-227 cimH C COG3493 Na citrate symporter
MLNPHKMC_03986 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
MLNPHKMC_03987 3.8e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MLNPHKMC_03988 2.8e-310 cydD V ATP-binding
MLNPHKMC_03989 0.0 cydD V ATP-binding protein
MLNPHKMC_03990 1.6e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MLNPHKMC_03991 5e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
MLNPHKMC_03992 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
MLNPHKMC_03993 8.1e-46 yxlC S Family of unknown function (DUF5345)
MLNPHKMC_03994 4.9e-28
MLNPHKMC_03995 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
MLNPHKMC_03996 9.7e-166 yxlF V ABC transporter, ATP-binding protein
MLNPHKMC_03997 2e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLNPHKMC_03998 1.4e-212 yxlH EGP Major facilitator Superfamily
MLNPHKMC_03999 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MLNPHKMC_04000 2.5e-109 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MLNPHKMC_04001 1.1e-19 yxzF
MLNPHKMC_04002 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
MLNPHKMC_04003 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
MLNPHKMC_04004 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLNPHKMC_04005 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MLNPHKMC_04006 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLNPHKMC_04007 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MLNPHKMC_04008 1.5e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
MLNPHKMC_04009 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MLNPHKMC_04010 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLNPHKMC_04011 8e-232 dltB M membrane protein involved in D-alanine export
MLNPHKMC_04012 2.8e-290 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLNPHKMC_04013 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MLNPHKMC_04014 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
MLNPHKMC_04015 1.7e-128 ynfM EGP Major facilitator Superfamily
MLNPHKMC_04016 2e-41 4.1.1.44 S Carboxymuconolactone decarboxylase family
MLNPHKMC_04017 6.2e-93 K Helix-turn-helix XRE-family like proteins
MLNPHKMC_04018 2.8e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
MLNPHKMC_04019 1.7e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLNPHKMC_04020 4e-87 ywaE K Transcriptional regulator
MLNPHKMC_04021 4.5e-121 ywaF S Integral membrane protein
MLNPHKMC_04022 2.6e-168 gspA M General stress
MLNPHKMC_04023 1.2e-152 sacY K transcriptional antiterminator
MLNPHKMC_04024 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLNPHKMC_04025 6.4e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
MLNPHKMC_04026 7.8e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLNPHKMC_04027 3.5e-123 ywbB S Protein of unknown function (DUF2711)
MLNPHKMC_04028 7.6e-67 ywbC 4.4.1.5 E glyoxalase
MLNPHKMC_04029 8.6e-218 ywbD 2.1.1.191 J Methyltransferase
MLNPHKMC_04030 3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
MLNPHKMC_04031 1.1e-207 ywbF EGP Major facilitator Superfamily
MLNPHKMC_04032 6.8e-111 ywbG M effector of murein hydrolase
MLNPHKMC_04033 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MLNPHKMC_04034 4.3e-153 ywbI K Transcriptional regulator
MLNPHKMC_04035 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MLNPHKMC_04036 2e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MLNPHKMC_04037 1.5e-253 P COG0672 High-affinity Fe2 Pb2 permease
MLNPHKMC_04038 1.9e-185 ycdO P periplasmic lipoprotein involved in iron transport
MLNPHKMC_04039 1.7e-224 ywbN P Dyp-type peroxidase family protein
MLNPHKMC_04040 8.1e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MLNPHKMC_04041 1.5e-267 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLNPHKMC_04042 2.9e-48 ywcB S Protein of unknown function, DUF485
MLNPHKMC_04044 1.1e-121 ywcC K transcriptional regulator
MLNPHKMC_04045 9.5e-60 gtcA S GtrA-like protein
MLNPHKMC_04046 1.4e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLNPHKMC_04047 1.1e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MLNPHKMC_04048 1e-35 ywzA S membrane
MLNPHKMC_04049 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MLNPHKMC_04050 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLNPHKMC_04051 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MLNPHKMC_04052 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MLNPHKMC_04053 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
MLNPHKMC_04054 2.9e-202 rodA D Belongs to the SEDS family
MLNPHKMC_04055 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MLNPHKMC_04056 1.8e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLNPHKMC_04057 0.0 vpr O Belongs to the peptidase S8 family
MLNPHKMC_04059 7e-150 sacT K transcriptional antiterminator
MLNPHKMC_04060 1e-139 focA P Formate/nitrite transporter
MLNPHKMC_04061 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLNPHKMC_04062 3.4e-293 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
MLNPHKMC_04063 2e-28 ywdA
MLNPHKMC_04064 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MLNPHKMC_04065 1.3e-57 pex K Transcriptional regulator PadR-like family
MLNPHKMC_04066 1.4e-113 ywdD
MLNPHKMC_04068 4.7e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
MLNPHKMC_04069 3.3e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MLNPHKMC_04070 1.4e-259 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MLNPHKMC_04071 5e-48 ywdI S Family of unknown function (DUF5327)
MLNPHKMC_04072 3.7e-238 ywdJ F Xanthine uracil
MLNPHKMC_04073 4.3e-59 ywdK S small membrane protein
MLNPHKMC_04074 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MLNPHKMC_04075 2.4e-144 spsA M Spore Coat
MLNPHKMC_04076 1.2e-266 spsB M Capsule polysaccharide biosynthesis protein
MLNPHKMC_04077 2.1e-224 spsC E Belongs to the DegT DnrJ EryC1 family
MLNPHKMC_04078 3.4e-163 spsD 2.3.1.210 K Spore Coat
MLNPHKMC_04079 2.7e-213 spsE 2.5.1.56 M acid synthase
MLNPHKMC_04080 1.2e-126 spsF M Spore Coat
MLNPHKMC_04081 3.6e-188 spsG M Spore Coat
MLNPHKMC_04082 2.1e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MLNPHKMC_04083 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MLNPHKMC_04084 1.3e-156 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MLNPHKMC_04085 1.8e-86 spsL 5.1.3.13 M Spore Coat
MLNPHKMC_04086 9.8e-77
MLNPHKMC_04087 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MLNPHKMC_04088 1.3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLNPHKMC_04089 0.0 rocB E arginine degradation protein
MLNPHKMC_04090 1.3e-260 lysP E amino acid
MLNPHKMC_04091 6.6e-205 ywfA EGP Major facilitator Superfamily
MLNPHKMC_04092 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MLNPHKMC_04093 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MLNPHKMC_04094 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLNPHKMC_04095 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MLNPHKMC_04096 7.3e-209 bacE EGP Major facilitator Superfamily
MLNPHKMC_04097 2.8e-232 ywfG 2.6.1.83 E Aminotransferase class I and II
MLNPHKMC_04098 2.2e-137 IQ Enoyl-(Acyl carrier protein) reductase
MLNPHKMC_04099 1.1e-146 ywfI C May function as heme-dependent peroxidase
MLNPHKMC_04100 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MLNPHKMC_04101 1.1e-156 cysL K Transcriptional regulator
MLNPHKMC_04102 3.3e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MLNPHKMC_04103 7.5e-158 ywfM EG EamA-like transporter family
MLNPHKMC_04104 1.5e-109 rsfA_1
MLNPHKMC_04105 3.1e-36 ywzC S Belongs to the UPF0741 family
MLNPHKMC_04106 1.9e-255 ywfO S COG1078 HD superfamily phosphohydrolases
MLNPHKMC_04107 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
MLNPHKMC_04108 1.4e-78 yffB K Transcriptional regulator
MLNPHKMC_04109 4.4e-237 mmr U Major Facilitator Superfamily
MLNPHKMC_04111 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLNPHKMC_04112 3.3e-71 ywhA K Transcriptional regulator
MLNPHKMC_04113 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MLNPHKMC_04114 5.1e-119 ywhC S Peptidase family M50
MLNPHKMC_04115 5.2e-95 ywhD S YwhD family
MLNPHKMC_04116 2.6e-34
MLNPHKMC_04117 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MLNPHKMC_04118 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MLNPHKMC_04119 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
MLNPHKMC_04121 1.4e-57 V ATPases associated with a variety of cellular activities
MLNPHKMC_04124 1.7e-20
MLNPHKMC_04127 2.6e-78 S aspartate phosphatase
MLNPHKMC_04128 2.7e-191 ywhK CO amine dehydrogenase activity
MLNPHKMC_04129 1.1e-245 ywhL CO amine dehydrogenase activity
MLNPHKMC_04131 4.3e-247 L Peptidase, M16
MLNPHKMC_04132 1e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
MLNPHKMC_04133 1.2e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MLNPHKMC_04134 3.3e-132 cbiO V ABC transporter
MLNPHKMC_04136 1.3e-267 C Fe-S oxidoreductases
MLNPHKMC_04137 1e-07 S Bacteriocin subtilosin A
MLNPHKMC_04138 4.7e-73 ywiB S protein conserved in bacteria
MLNPHKMC_04139 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MLNPHKMC_04140 3e-213 narK P COG2223 Nitrate nitrite transporter
MLNPHKMC_04141 3.8e-128 fnr K helix_turn_helix, cAMP Regulatory protein
MLNPHKMC_04142 2.6e-137 ywiC S YwiC-like protein
MLNPHKMC_04143 2e-85 arfM T cyclic nucleotide binding
MLNPHKMC_04144 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLNPHKMC_04145 5.7e-296 narH 1.7.5.1 C Nitrate reductase, beta
MLNPHKMC_04146 6.2e-94 narJ 1.7.5.1 C nitrate reductase
MLNPHKMC_04147 5.3e-124 narI 1.7.5.1 C nitrate reductase, gamma
MLNPHKMC_04148 5.5e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLNPHKMC_04149 0.0 ywjA V ABC transporter
MLNPHKMC_04150 2e-94 ywjB H RibD C-terminal domain
MLNPHKMC_04151 2.7e-42 ywjC
MLNPHKMC_04152 4.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MLNPHKMC_04153 7.1e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MLNPHKMC_04154 0.0 fadF C COG0247 Fe-S oxidoreductase
MLNPHKMC_04155 1.4e-193 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MLNPHKMC_04156 1.1e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MLNPHKMC_04157 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MLNPHKMC_04158 1.8e-90 ywjG S Domain of unknown function (DUF2529)
MLNPHKMC_04159 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
MLNPHKMC_04160 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MLNPHKMC_04161 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MLNPHKMC_04162 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLNPHKMC_04163 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MLNPHKMC_04164 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MLNPHKMC_04165 1.1e-32 rpmE J Binds the 23S rRNA
MLNPHKMC_04166 7e-104 tdk 2.7.1.21 F thymidine kinase
MLNPHKMC_04167 0.0 sfcA 1.1.1.38 C malic enzyme
MLNPHKMC_04168 8.6e-160 ywkB S Membrane transport protein
MLNPHKMC_04169 6.4e-75 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MLNPHKMC_04170 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLNPHKMC_04171 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MLNPHKMC_04172 1.2e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MLNPHKMC_04174 3.7e-55 ywlA S Uncharacterised protein family (UPF0715)
MLNPHKMC_04175 3e-111 spoIIR S stage II sporulation protein R
MLNPHKMC_04176 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
MLNPHKMC_04177 1.8e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MLNPHKMC_04178 1.7e-91 mntP P Probably functions as a manganese efflux pump
MLNPHKMC_04179 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLNPHKMC_04180 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MLNPHKMC_04181 6.1e-94 ywlG S Belongs to the UPF0340 family
MLNPHKMC_04182 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLNPHKMC_04183 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MLNPHKMC_04184 2.5e-62 atpI S ATP synthase
MLNPHKMC_04185 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
MLNPHKMC_04186 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLNPHKMC_04187 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MLNPHKMC_04188 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLNPHKMC_04189 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MLNPHKMC_04190 1.9e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MLNPHKMC_04191 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MLNPHKMC_04192 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MLNPHKMC_04193 4.3e-88 ywmA
MLNPHKMC_04194 1.3e-32 ywzB S membrane
MLNPHKMC_04195 8.2e-134 ywmB S TATA-box binding
MLNPHKMC_04196 6.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLNPHKMC_04197 7.8e-175 spoIID D Stage II sporulation protein D
MLNPHKMC_04198 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
MLNPHKMC_04199 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
MLNPHKMC_04201 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MLNPHKMC_04202 5e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MLNPHKMC_04203 6.1e-104 S response regulator aspartate phosphatase
MLNPHKMC_04204 3.9e-84 ywmF S Peptidase M50
MLNPHKMC_04205 3.8e-11 csbD K CsbD-like
MLNPHKMC_04206 8.5e-22 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MLNPHKMC_04207 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MLNPHKMC_04208 1e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MLNPHKMC_04209 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MLNPHKMC_04210 1.7e-64 ywnA K Transcriptional regulator
MLNPHKMC_04211 2e-112 ywnB S NAD(P)H-binding
MLNPHKMC_04212 2.6e-59 ywnC S Family of unknown function (DUF5362)
MLNPHKMC_04213 7.7e-143 mta K transcriptional
MLNPHKMC_04214 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLNPHKMC_04215 2.2e-70 ywnF S Family of unknown function (DUF5392)
MLNPHKMC_04216 1.1e-189 spsF 2.5.1.56, 2.7.7.92 M NeuB family
MLNPHKMC_04217 2.7e-14 ywnC S Family of unknown function (DUF5362)
MLNPHKMC_04218 1.7e-87 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MLNPHKMC_04219 6.9e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MLNPHKMC_04220 3e-72 ywnJ S VanZ like family
MLNPHKMC_04221 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MLNPHKMC_04222 1.6e-58 nrgB K Belongs to the P(II) protein family
MLNPHKMC_04223 7.4e-225 amt P Ammonium transporter
MLNPHKMC_04224 7.5e-77
MLNPHKMC_04225 2.6e-103 phzA Q Isochorismatase family
MLNPHKMC_04226 2.7e-239 ywoD EGP Major facilitator superfamily
MLNPHKMC_04227 7.5e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
MLNPHKMC_04228 4.4e-229 ywoF P Right handed beta helix region
MLNPHKMC_04229 2.7e-211 ywoG EGP Major facilitator Superfamily
MLNPHKMC_04230 2.1e-70 ywoH K COG1846 Transcriptional regulators
MLNPHKMC_04231 3e-44 spoIIID K Stage III sporulation protein D
MLNPHKMC_04232 3.5e-180 mbl D Rod shape-determining protein
MLNPHKMC_04233 3.4e-125 flhO N flagellar basal body
MLNPHKMC_04234 2.6e-141 flhP N flagellar basal body
MLNPHKMC_04235 4.4e-197 S aspartate phosphatase
MLNPHKMC_04236 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MLNPHKMC_04237 9.9e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MLNPHKMC_04238 0.0 ywpD T PhoQ Sensor
MLNPHKMC_04239 4.5e-173 M1-574 T Transcriptional regulatory protein, C terminal
MLNPHKMC_04240 0.0 M1-568 M cell wall anchor domain
MLNPHKMC_04241 5.1e-84 srtA 3.4.22.70 M Sortase family
MLNPHKMC_04242 1.1e-66 ywpF S YwpF-like protein
MLNPHKMC_04243 1.3e-66 ywpG
MLNPHKMC_04244 3.7e-57 ssbB L Single-stranded DNA-binding protein
MLNPHKMC_04245 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
MLNPHKMC_04246 7.4e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
MLNPHKMC_04247 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLNPHKMC_04248 1.3e-306 ywqB S SWIM zinc finger
MLNPHKMC_04249 1.2e-17
MLNPHKMC_04250 1.3e-115 ywqC M biosynthesis protein
MLNPHKMC_04251 2.2e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MLNPHKMC_04252 6.7e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MLNPHKMC_04253 4.4e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLNPHKMC_04254 2.9e-153 ywqG S Domain of unknown function (DUF1963)
MLNPHKMC_04255 9.7e-23 S Domain of unknown function (DUF5082)
MLNPHKMC_04256 1.3e-38 ywqI S Family of unknown function (DUF5344)
MLNPHKMC_04257 6e-242 ywqJ S Pre-toxin TG
MLNPHKMC_04258 1.7e-25
MLNPHKMC_04259 4.3e-116 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MLNPHKMC_04260 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
MLNPHKMC_04261 1.2e-103 ywrB P Chromate transporter
MLNPHKMC_04262 8e-82 ywrC K Transcriptional regulator
MLNPHKMC_04263 6.1e-304 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MLNPHKMC_04264 2.5e-53 S Domain of unknown function (DUF4181)
MLNPHKMC_04265 6.9e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLNPHKMC_04266 1.3e-12
MLNPHKMC_04267 6.2e-207 cotH M Spore Coat
MLNPHKMC_04269 2e-56 soj D Cellulose biosynthesis protein BcsQ
MLNPHKMC_04270 1.4e-81 S COG0457 FOG TPR repeat
MLNPHKMC_04274 5.1e-08 yddI
MLNPHKMC_04275 5.9e-84 yddH M NlpC/P60 family
MLNPHKMC_04276 1.5e-71 yddG S maturation of SSU-rRNA
MLNPHKMC_04277 3.8e-12 S Domain of unknown function with cystatin-like fold (DUF4467)
MLNPHKMC_04278 1.9e-267 yddE S AAA-like domain
MLNPHKMC_04279 3e-17 yddD S TcpE family
MLNPHKMC_04281 3.2e-49 yukA S TraM recognition site of TraD and TraG
MLNPHKMC_04284 7.5e-59 ygjR S Oxidoreductase
MLNPHKMC_04285 1.1e-93 hxlB 4.1.2.43, 5.3.1.27 M sugar phosphate isomerase involved in capsule formation
MLNPHKMC_04286 9.5e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MLNPHKMC_04287 6.8e-65 hxlR K transcriptional
MLNPHKMC_04288 1.6e-282 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MLNPHKMC_04290 1e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MLNPHKMC_04291 3.6e-85
MLNPHKMC_04293 1.4e-256 pgi 5.3.1.9 G Belongs to the GPI family
MLNPHKMC_04294 2.8e-42 pinR3 L PFAM Resolvase
MLNPHKMC_04295 1.3e-199 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)