ORF_ID e_value Gene_name EC_number CAZy COGs Description
MHPLLIDD_00001 1.9e-07 K Transcriptional regulator
MHPLLIDD_00002 2.1e-126 ymaC S Replication protein
MHPLLIDD_00003 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
MHPLLIDD_00004 8.9e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
MHPLLIDD_00005 5.4e-50 ebrA P Small Multidrug Resistance protein
MHPLLIDD_00007 2.1e-46 ymaF S YmaF family
MHPLLIDD_00008 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHPLLIDD_00009 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MHPLLIDD_00010 8.2e-23
MHPLLIDD_00011 4.5e-22 ymzA
MHPLLIDD_00012 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MHPLLIDD_00013 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHPLLIDD_00014 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHPLLIDD_00015 2e-109 ymaB
MHPLLIDD_00016 2.6e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MHPLLIDD_00017 1.7e-176 spoVK O stage V sporulation protein K
MHPLLIDD_00018 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHPLLIDD_00019 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MHPLLIDD_00020 1.1e-68 glnR K transcriptional
MHPLLIDD_00021 7e-261 glnA 6.3.1.2 E glutamine synthetase
MHPLLIDD_00022 4e-135 L Belongs to the 'phage' integrase family
MHPLLIDD_00023 4.7e-50 1.15.1.2 C Rubrerythrin
MHPLLIDD_00024 5.5e-13 K Cro/C1-type HTH DNA-binding domain
MHPLLIDD_00026 7.3e-53 S Phage regulatory protein Rha (Phage_pRha)
MHPLLIDD_00027 7.4e-20
MHPLLIDD_00029 6.6e-20 S Uncharacterized protein YqaH
MHPLLIDD_00031 1.2e-92 S DNA protection
MHPLLIDD_00032 1.2e-166 tadZ D AAA domain
MHPLLIDD_00034 9e-72 S Protein of unknown function (DUF669)
MHPLLIDD_00035 0.0 S hydrolase activity
MHPLLIDD_00036 3.1e-72
MHPLLIDD_00037 5.1e-93 S nuclease activity
MHPLLIDD_00038 9.5e-81
MHPLLIDD_00041 1.5e-59
MHPLLIDD_00042 2e-07
MHPLLIDD_00045 1.9e-44 T Histidine kinase
MHPLLIDD_00046 8.1e-50 V HNH endonuclease
MHPLLIDD_00047 6.8e-79 L phage terminase small subunit
MHPLLIDD_00048 3e-304 S Terminase
MHPLLIDD_00049 8.2e-174 S Phage portal protein
MHPLLIDD_00050 6.8e-81 S peptidase activity
MHPLLIDD_00051 2.3e-155 gp36 S capsid protein
MHPLLIDD_00052 3.8e-20
MHPLLIDD_00053 1e-37 S Phage gp6-like head-tail connector protein
MHPLLIDD_00054 8e-38 S Phage head-tail joining protein
MHPLLIDD_00055 1.4e-50 S Bacteriophage HK97-gp10, putative tail-component
MHPLLIDD_00057 1.6e-79 N Phage major tail protein phi13
MHPLLIDD_00060 0.0 D phage tail tape measure protein
MHPLLIDD_00061 7.6e-112 S Phage tail protein
MHPLLIDD_00062 2.6e-220 NU Prophage endopeptidase tail
MHPLLIDD_00063 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
MHPLLIDD_00064 2.8e-88
MHPLLIDD_00065 1e-12
MHPLLIDD_00067 2.2e-95 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
MHPLLIDD_00068 2.3e-56 S Pfam:Phage_holin_4_1
MHPLLIDD_00069 4.8e-126 xlyB 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MHPLLIDD_00070 6.2e-79 S SMI1-KNR4 cell-wall
MHPLLIDD_00071 4.9e-286 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MHPLLIDD_00072 2.2e-106 S aspartate phosphatase
MHPLLIDD_00076 1.1e-09
MHPLLIDD_00077 1.6e-31
MHPLLIDD_00078 2.1e-16
MHPLLIDD_00079 8.9e-90 G SMI1-KNR4 cell-wall
MHPLLIDD_00080 3.1e-113 ynaC
MHPLLIDD_00081 4.1e-11 S Protein of unknown function (DUF1433)
MHPLLIDD_00082 2e-97 ynaD J Acetyltransferase (GNAT) domain
MHPLLIDD_00083 4.1e-73 S CAAX protease self-immunity
MHPLLIDD_00084 6.1e-08 S Uncharacterised protein family (UPF0715)
MHPLLIDD_00085 5.5e-20 K Cro/C1-type HTH DNA-binding domain
MHPLLIDD_00086 2.1e-117 ynaE S Domain of unknown function (DUF3885)
MHPLLIDD_00087 8.6e-15 ynaF
MHPLLIDD_00089 8.7e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
MHPLLIDD_00090 7.9e-255 xynT G MFS/sugar transport protein
MHPLLIDD_00091 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MHPLLIDD_00092 6.8e-212 xylR GK ROK family
MHPLLIDD_00093 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MHPLLIDD_00094 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
MHPLLIDD_00095 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
MHPLLIDD_00096 1.4e-254 iolT EGP Major facilitator Superfamily
MHPLLIDD_00097 4.5e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHPLLIDD_00099 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MHPLLIDD_00100 5.2e-15
MHPLLIDD_00103 2.5e-163 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHPLLIDD_00105 8.9e-128 S Domain of unknown function, YrpD
MHPLLIDD_00108 7.9e-25 tatA U protein secretion
MHPLLIDD_00109 1.8e-71
MHPLLIDD_00110 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
MHPLLIDD_00113 2.8e-52 gerAA EG Spore germination protein
MHPLLIDD_00114 4.8e-144 gerAA EG Spore germination protein
MHPLLIDD_00115 3.4e-88 gerLC S Spore germination protein
MHPLLIDD_00116 7.7e-154 yndG S DoxX-like family
MHPLLIDD_00117 2.6e-117 yndH S Domain of unknown function (DUF4166)
MHPLLIDD_00118 0.0 yndJ S YndJ-like protein
MHPLLIDD_00120 8.6e-139 yndL S Replication protein
MHPLLIDD_00121 5.8e-74 yndM S Protein of unknown function (DUF2512)
MHPLLIDD_00122 1.3e-75 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MHPLLIDD_00123 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHPLLIDD_00124 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MHPLLIDD_00125 5e-111 yneB L resolvase
MHPLLIDD_00126 1.3e-32 ynzC S UPF0291 protein
MHPLLIDD_00127 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHPLLIDD_00128 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
MHPLLIDD_00129 1.8e-28 yneF S UPF0154 protein
MHPLLIDD_00130 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
MHPLLIDD_00131 7.1e-127 ccdA O cytochrome c biogenesis protein
MHPLLIDD_00132 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MHPLLIDD_00133 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MHPLLIDD_00134 4.2e-74 yneK S Protein of unknown function (DUF2621)
MHPLLIDD_00135 1.2e-64 hspX O Spore coat protein
MHPLLIDD_00136 3.9e-19 sspP S Belongs to the SspP family
MHPLLIDD_00137 2.2e-14 sspO S Belongs to the SspO family
MHPLLIDD_00138 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MHPLLIDD_00139 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MHPLLIDD_00141 3.1e-08 sspN S Small acid-soluble spore protein N family
MHPLLIDD_00142 3.9e-35 tlp S Belongs to the Tlp family
MHPLLIDD_00143 2e-73 yneP S Thioesterase-like superfamily
MHPLLIDD_00144 1.7e-53 yneQ
MHPLLIDD_00145 4.1e-49 yneR S Belongs to the HesB IscA family
MHPLLIDD_00146 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHPLLIDD_00147 8.6e-69 yccU S CoA-binding protein
MHPLLIDD_00148 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHPLLIDD_00149 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHPLLIDD_00150 2.3e-12
MHPLLIDD_00151 1.3e-57 ynfC
MHPLLIDD_00152 1.8e-251 agcS E Sodium alanine symporter
MHPLLIDD_00153 9.9e-296 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
MHPLLIDD_00155 1.1e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
MHPLLIDD_00156 7.8e-296 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
MHPLLIDD_00157 1.6e-79 yngA S membrane
MHPLLIDD_00158 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MHPLLIDD_00159 5.5e-104 yngC S membrane-associated protein
MHPLLIDD_00160 2.6e-230 nrnB S phosphohydrolase (DHH superfamily)
MHPLLIDD_00161 1.5e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MHPLLIDD_00162 6.4e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MHPLLIDD_00163 2.9e-165 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
MHPLLIDD_00164 2.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MHPLLIDD_00165 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MHPLLIDD_00166 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHPLLIDD_00167 1.2e-208 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MHPLLIDD_00168 5e-303 yngK T Glycosyl hydrolase-like 10
MHPLLIDD_00169 4e-63 yngL S Protein of unknown function (DUF1360)
MHPLLIDD_00170 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MHPLLIDD_00171 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPLLIDD_00172 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPLLIDD_00173 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPLLIDD_00174 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPLLIDD_00175 1.4e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MHPLLIDD_00176 5.6e-191 yoxA 5.1.3.3 G Aldose 1-epimerase
MHPLLIDD_00177 2.3e-246 yoeA V MATE efflux family protein
MHPLLIDD_00178 2.6e-97 yoeB S IseA DL-endopeptidase inhibitor
MHPLLIDD_00180 2.2e-96 L Integrase
MHPLLIDD_00181 3e-34 yoeD G Helix-turn-helix domain
MHPLLIDD_00182 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MHPLLIDD_00183 2.3e-156 gltR1 K Transcriptional regulator
MHPLLIDD_00184 8e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MHPLLIDD_00185 6.6e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MHPLLIDD_00186 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MHPLLIDD_00187 3.9e-154 gltC K Transcriptional regulator
MHPLLIDD_00188 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHPLLIDD_00189 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHPLLIDD_00190 2e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MHPLLIDD_00191 7.7e-121 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPLLIDD_00192 7e-39 yoxC S Bacterial protein of unknown function (DUF948)
MHPLLIDD_00193 2.5e-130 yoxB
MHPLLIDD_00194 5.6e-92 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHPLLIDD_00195 3.8e-126 V ABC-2 family transporter protein
MHPLLIDD_00196 2.9e-94 V ABC-2 family transporter protein
MHPLLIDD_00197 1.8e-138 V AAA domain, putative AbiEii toxin, Type IV TA system
MHPLLIDD_00198 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
MHPLLIDD_00199 1.2e-233 yoaB EGP Major facilitator Superfamily
MHPLLIDD_00200 5.3e-278 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MHPLLIDD_00201 1.7e-70 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHPLLIDD_00202 3.8e-99 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHPLLIDD_00203 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHPLLIDD_00204 6.6e-32 yoaF
MHPLLIDD_00205 3e-172 iolT EGP Major facilitator Superfamily
MHPLLIDD_00206 1.6e-205 S Oxidoreductase family, C-terminal alpha/beta domain
MHPLLIDD_00207 3.2e-151 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
MHPLLIDD_00208 3.3e-90 purR K Transcriptional regulator
MHPLLIDD_00209 2.2e-07
MHPLLIDD_00210 7e-14
MHPLLIDD_00211 1.5e-38 S Protein of unknown function (DUF4025)
MHPLLIDD_00212 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
MHPLLIDD_00213 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
MHPLLIDD_00214 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
MHPLLIDD_00215 2.3e-111 yoaK S Membrane
MHPLLIDD_00216 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
MHPLLIDD_00217 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
MHPLLIDD_00219 7.9e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
MHPLLIDD_00222 7.3e-86
MHPLLIDD_00223 9.3e-172 yoaR V vancomycin resistance protein
MHPLLIDD_00224 2.8e-74 yoaS S Protein of unknown function (DUF2975)
MHPLLIDD_00225 4.4e-30 yozG K Transcriptional regulator
MHPLLIDD_00226 5.3e-147 yoaT S Protein of unknown function (DUF817)
MHPLLIDD_00227 8.6e-159 yoaU K LysR substrate binding domain
MHPLLIDD_00228 1.5e-158 yijE EG EamA-like transporter family
MHPLLIDD_00229 1.8e-77 yoaW
MHPLLIDD_00230 4.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MHPLLIDD_00231 3.8e-165 bla 3.5.2.6 V beta-lactamase
MHPLLIDD_00234 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MHPLLIDD_00235 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
MHPLLIDD_00237 3.2e-45
MHPLLIDD_00239 2.7e-176 T PhoQ Sensor
MHPLLIDD_00240 1.2e-63 kdpC 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MHPLLIDD_00241 0.0 kdpB 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MHPLLIDD_00242 2.9e-272 kdpA 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MHPLLIDD_00244 2.8e-84 S SMI1-KNR4 cell-wall
MHPLLIDD_00245 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MHPLLIDD_00246 9.1e-101 yokH G SMI1 / KNR4 family
MHPLLIDD_00247 4.4e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
MHPLLIDD_00248 0.0 yobO M Pectate lyase superfamily protein
MHPLLIDD_00249 1.4e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
MHPLLIDD_00250 3.8e-136 yobQ K helix_turn_helix, arabinose operon control protein
MHPLLIDD_00251 5.3e-141 yobR 2.3.1.1 J FR47-like protein
MHPLLIDD_00252 1.3e-97 yobS K Transcriptional regulator
MHPLLIDD_00253 2.8e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
MHPLLIDD_00254 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
MHPLLIDD_00255 6.2e-171 yobV K WYL domain
MHPLLIDD_00256 1.8e-90 yobW
MHPLLIDD_00257 1e-51 czrA K transcriptional
MHPLLIDD_00258 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHPLLIDD_00259 1.5e-92 yozB S membrane
MHPLLIDD_00260 1.3e-142
MHPLLIDD_00261 1.2e-93 yocC
MHPLLIDD_00262 1.5e-188 yocD 3.4.17.13 V peptidase S66
MHPLLIDD_00263 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MHPLLIDD_00264 1.7e-196 desK 2.7.13.3 T Histidine kinase
MHPLLIDD_00265 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHPLLIDD_00266 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
MHPLLIDD_00267 0.0 recQ 3.6.4.12 L DNA helicase
MHPLLIDD_00268 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHPLLIDD_00269 3.3e-83 dksA T general stress protein
MHPLLIDD_00270 6.4e-54 yocL
MHPLLIDD_00271 6.6e-34
MHPLLIDD_00272 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
MHPLLIDD_00273 1.1e-40 yozN
MHPLLIDD_00274 1.9e-36 yocN
MHPLLIDD_00275 4.2e-56 yozO S Bacterial PH domain
MHPLLIDD_00276 2.7e-31 yozC
MHPLLIDD_00277 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MHPLLIDD_00278 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
MHPLLIDD_00279 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
MHPLLIDD_00280 9.9e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MHPLLIDD_00281 8.6e-168 yocS S -transporter
MHPLLIDD_00282 3.5e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MHPLLIDD_00283 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MHPLLIDD_00284 0.0 yojO P Von Willebrand factor
MHPLLIDD_00285 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
MHPLLIDD_00286 1.5e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MHPLLIDD_00287 4.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MHPLLIDD_00288 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
MHPLLIDD_00289 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHPLLIDD_00291 4.2e-245 norM V Multidrug efflux pump
MHPLLIDD_00292 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHPLLIDD_00293 2.1e-125 yojG S deacetylase
MHPLLIDD_00294 2.2e-60 yojF S Protein of unknown function (DUF1806)
MHPLLIDD_00295 1.5e-43
MHPLLIDD_00296 6.6e-162 rarD S -transporter
MHPLLIDD_00297 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
MHPLLIDD_00298 3.4e-09
MHPLLIDD_00299 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
MHPLLIDD_00300 3.8e-66 yodA S tautomerase
MHPLLIDD_00301 1.7e-57 yodB K transcriptional
MHPLLIDD_00302 4.8e-108 yodC C nitroreductase
MHPLLIDD_00303 3.8e-113 mhqD S Carboxylesterase
MHPLLIDD_00304 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
MHPLLIDD_00305 6.2e-28 S Protein of unknown function (DUF3311)
MHPLLIDD_00306 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHPLLIDD_00307 1.6e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MHPLLIDD_00308 1.7e-128 yodH Q Methyltransferase
MHPLLIDD_00309 5.2e-24 yodI
MHPLLIDD_00310 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MHPLLIDD_00311 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MHPLLIDD_00312 5.3e-09
MHPLLIDD_00313 3.6e-54 yodL S YodL-like
MHPLLIDD_00314 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
MHPLLIDD_00315 2.8e-24 yozD S YozD-like protein
MHPLLIDD_00317 1.4e-124 yodN
MHPLLIDD_00318 1.4e-36 yozE S Belongs to the UPF0346 family
MHPLLIDD_00319 2.9e-47 yokU S YokU-like protein, putative antitoxin
MHPLLIDD_00320 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
MHPLLIDD_00321 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
MHPLLIDD_00322 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
MHPLLIDD_00323 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MHPLLIDD_00324 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MHPLLIDD_00325 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHPLLIDD_00327 8.3e-145 yiiD K acetyltransferase
MHPLLIDD_00328 1e-256 cgeD M maturation of the outermost layer of the spore
MHPLLIDD_00329 3.5e-38 cgeC
MHPLLIDD_00330 1.2e-65 cgeA
MHPLLIDD_00331 2e-185 cgeB S Spore maturation protein
MHPLLIDD_00332 5.2e-212 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
MHPLLIDD_00333 1.3e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
MHPLLIDD_00334 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MHPLLIDD_00335 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHPLLIDD_00336 1.6e-70 ypoP K transcriptional
MHPLLIDD_00337 3.8e-222 mepA V MATE efflux family protein
MHPLLIDD_00338 5.5e-29 ypmT S Uncharacterized ympT
MHPLLIDD_00339 1.1e-98 ypmS S protein conserved in bacteria
MHPLLIDD_00340 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
MHPLLIDD_00341 2.7e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MHPLLIDD_00342 3.1e-40 ypmP S Protein of unknown function (DUF2535)
MHPLLIDD_00343 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MHPLLIDD_00344 1.6e-185 pspF K Transcriptional regulator
MHPLLIDD_00345 4.2e-110 hlyIII S protein, Hemolysin III
MHPLLIDD_00346 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MHPLLIDD_00347 1.6e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHPLLIDD_00348 1.5e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHPLLIDD_00349 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MHPLLIDD_00350 7.8e-114 ypjP S YpjP-like protein
MHPLLIDD_00351 3.7e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
MHPLLIDD_00352 1.7e-75 yphP S Belongs to the UPF0403 family
MHPLLIDD_00353 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MHPLLIDD_00354 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
MHPLLIDD_00355 5.4e-107 ypgQ S phosphohydrolase
MHPLLIDD_00356 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MHPLLIDD_00357 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MHPLLIDD_00358 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MHPLLIDD_00359 7.9e-31 cspD K Cold-shock protein
MHPLLIDD_00360 3.8e-16 degR
MHPLLIDD_00361 1.8e-30 S Protein of unknown function (DUF2564)
MHPLLIDD_00362 3e-29 ypeQ S Zinc-finger
MHPLLIDD_00363 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
MHPLLIDD_00364 4.5e-106 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MHPLLIDD_00365 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
MHPLLIDD_00367 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
MHPLLIDD_00368 2e-07
MHPLLIDD_00369 8.5e-38 ypbS S Protein of unknown function (DUF2533)
MHPLLIDD_00370 0.0 ypbR S Dynamin family
MHPLLIDD_00372 7.4e-86 ypbQ S protein conserved in bacteria
MHPLLIDD_00373 8.2e-207 bcsA Q Naringenin-chalcone synthase
MHPLLIDD_00374 3.8e-227 pbuX F xanthine
MHPLLIDD_00375 4.4e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHPLLIDD_00376 3.9e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MHPLLIDD_00377 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MHPLLIDD_00378 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MHPLLIDD_00379 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MHPLLIDD_00380 7.4e-186 ptxS K transcriptional
MHPLLIDD_00381 1.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MHPLLIDD_00382 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPLLIDD_00383 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
MHPLLIDD_00385 1.2e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MHPLLIDD_00386 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHPLLIDD_00387 8.2e-91 ypsA S Belongs to the UPF0398 family
MHPLLIDD_00388 2.5e-236 yprB L RNase_H superfamily
MHPLLIDD_00389 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MHPLLIDD_00390 1.2e-80 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MHPLLIDD_00391 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
MHPLLIDD_00392 6.6e-47 yppG S YppG-like protein
MHPLLIDD_00394 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
MHPLLIDD_00397 5.4e-186 yppC S Protein of unknown function (DUF2515)
MHPLLIDD_00398 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHPLLIDD_00399 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
MHPLLIDD_00400 1.8e-92 ypoC
MHPLLIDD_00401 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHPLLIDD_00402 1.3e-128 dnaD L DNA replication protein DnaD
MHPLLIDD_00403 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
MHPLLIDD_00404 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MHPLLIDD_00405 4.9e-79 ypmB S protein conserved in bacteria
MHPLLIDD_00406 1.9e-22 ypmA S Protein of unknown function (DUF4264)
MHPLLIDD_00407 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MHPLLIDD_00408 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MHPLLIDD_00409 6.1e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MHPLLIDD_00410 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MHPLLIDD_00411 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHPLLIDD_00412 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHPLLIDD_00413 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MHPLLIDD_00414 1.7e-128 bshB1 S proteins, LmbE homologs
MHPLLIDD_00415 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MHPLLIDD_00416 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHPLLIDD_00417 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MHPLLIDD_00418 5.2e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MHPLLIDD_00419 1e-142 ypjB S sporulation protein
MHPLLIDD_00420 7.6e-98 ypjA S membrane
MHPLLIDD_00421 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MHPLLIDD_00422 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
MHPLLIDD_00423 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
MHPLLIDD_00424 4.2e-77 ypiF S Protein of unknown function (DUF2487)
MHPLLIDD_00425 1.1e-98 ypiB S Belongs to the UPF0302 family
MHPLLIDD_00426 4.1e-234 S COG0457 FOG TPR repeat
MHPLLIDD_00427 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MHPLLIDD_00428 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MHPLLIDD_00429 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHPLLIDD_00430 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHPLLIDD_00431 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHPLLIDD_00432 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MHPLLIDD_00433 8.1e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MHPLLIDD_00434 3.9e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHPLLIDD_00435 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHPLLIDD_00436 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MHPLLIDD_00437 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MHPLLIDD_00438 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MHPLLIDD_00439 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MHPLLIDD_00440 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MHPLLIDD_00441 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MHPLLIDD_00442 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MHPLLIDD_00443 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MHPLLIDD_00444 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MHPLLIDD_00445 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
MHPLLIDD_00446 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHPLLIDD_00447 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MHPLLIDD_00448 5.4e-138 yphF
MHPLLIDD_00449 1.6e-18 yphE S Protein of unknown function (DUF2768)
MHPLLIDD_00450 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MHPLLIDD_00451 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MHPLLIDD_00452 1.6e-28 ypzH
MHPLLIDD_00453 2.5e-161 seaA S YIEGIA protein
MHPLLIDD_00454 1.3e-102 yphA
MHPLLIDD_00455 1e-07 S YpzI-like protein
MHPLLIDD_00456 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MHPLLIDD_00457 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
MHPLLIDD_00458 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MHPLLIDD_00459 1.8e-23 S Family of unknown function (DUF5359)
MHPLLIDD_00460 9.2e-113 ypfA M Flagellar protein YcgR
MHPLLIDD_00461 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MHPLLIDD_00462 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MHPLLIDD_00463 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
MHPLLIDD_00464 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MHPLLIDD_00465 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MHPLLIDD_00466 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHPLLIDD_00467 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
MHPLLIDD_00468 2.8e-81 ypbF S Protein of unknown function (DUF2663)
MHPLLIDD_00469 4.6e-81 ypbE M Lysin motif
MHPLLIDD_00470 2.2e-100 ypbD S metal-dependent membrane protease
MHPLLIDD_00471 3.2e-286 recQ 3.6.4.12 L DNA helicase
MHPLLIDD_00472 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
MHPLLIDD_00473 4.7e-41 fer C Ferredoxin
MHPLLIDD_00474 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHPLLIDD_00475 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHPLLIDD_00476 2.2e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MHPLLIDD_00477 7.3e-195 rsiX
MHPLLIDD_00478 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
MHPLLIDD_00479 0.0 resE 2.7.13.3 T Histidine kinase
MHPLLIDD_00480 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPLLIDD_00481 9.7e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MHPLLIDD_00482 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MHPLLIDD_00483 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MHPLLIDD_00484 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MHPLLIDD_00485 1.9e-87 spmB S Spore maturation protein
MHPLLIDD_00486 3.5e-103 spmA S Spore maturation protein
MHPLLIDD_00487 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MHPLLIDD_00488 7.6e-97 ypuI S Protein of unknown function (DUF3907)
MHPLLIDD_00489 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHPLLIDD_00490 2.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHPLLIDD_00491 1.4e-92 ypuF S Domain of unknown function (DUF309)
MHPLLIDD_00492 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHPLLIDD_00493 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MHPLLIDD_00494 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MHPLLIDD_00495 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
MHPLLIDD_00496 2.4e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MHPLLIDD_00497 7.8e-55 ypuD
MHPLLIDD_00498 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MHPLLIDD_00499 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
MHPLLIDD_00500 3.4e-13 S PAP2 superfamily
MHPLLIDD_00502 1.2e-07 eaeH M Domain of Unknown Function (DUF1259)
MHPLLIDD_00504 1.9e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHPLLIDD_00505 7.3e-07
MHPLLIDD_00509 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHPLLIDD_00510 3.6e-149 ypuA S Secreted protein
MHPLLIDD_00511 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHPLLIDD_00512 1.4e-273 spoVAF EG Stage V sporulation protein AF
MHPLLIDD_00513 1.4e-110 spoVAEA S stage V sporulation protein
MHPLLIDD_00514 2.2e-57 spoVAEB S stage V sporulation protein
MHPLLIDD_00515 9e-192 spoVAD I Stage V sporulation protein AD
MHPLLIDD_00516 2.3e-78 spoVAC S stage V sporulation protein AC
MHPLLIDD_00517 1e-67 spoVAB S Stage V sporulation protein AB
MHPLLIDD_00518 7.4e-112 spoVAA S Stage V sporulation protein AA
MHPLLIDD_00519 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPLLIDD_00520 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MHPLLIDD_00521 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MHPLLIDD_00522 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MHPLLIDD_00523 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MHPLLIDD_00524 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MHPLLIDD_00525 2.6e-166 xerD L recombinase XerD
MHPLLIDD_00526 3.7e-37 S Protein of unknown function (DUF4227)
MHPLLIDD_00527 2e-79 fur P Belongs to the Fur family
MHPLLIDD_00528 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MHPLLIDD_00529 2e-32 yqkK
MHPLLIDD_00530 5.5e-242 mleA 1.1.1.38 C malic enzyme
MHPLLIDD_00531 3.1e-235 mleN C Na H antiporter
MHPLLIDD_00532 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MHPLLIDD_00533 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
MHPLLIDD_00534 4.5e-58 ansR K Transcriptional regulator
MHPLLIDD_00535 3e-223 yqxK 3.6.4.12 L DNA helicase
MHPLLIDD_00536 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MHPLLIDD_00538 7.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MHPLLIDD_00539 4e-14 yqkE S Protein of unknown function (DUF3886)
MHPLLIDD_00540 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MHPLLIDD_00541 9.4e-39 yqkC S Protein of unknown function (DUF2552)
MHPLLIDD_00542 2.8e-54 yqkB S Belongs to the HesB IscA family
MHPLLIDD_00543 4.7e-196 yqkA K GrpB protein
MHPLLIDD_00544 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
MHPLLIDD_00545 3.6e-87 yqjY K acetyltransferase
MHPLLIDD_00546 2.2e-49 S YolD-like protein
MHPLLIDD_00547 1.4e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHPLLIDD_00549 1.7e-224 yqjV G Major Facilitator Superfamily
MHPLLIDD_00551 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPLLIDD_00552 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
MHPLLIDD_00553 1.9e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MHPLLIDD_00554 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPLLIDD_00555 4.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
MHPLLIDD_00556 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHPLLIDD_00557 0.0 rocB E arginine degradation protein
MHPLLIDD_00558 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MHPLLIDD_00559 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MHPLLIDD_00560 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MHPLLIDD_00561 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHPLLIDD_00562 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHPLLIDD_00563 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHPLLIDD_00564 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHPLLIDD_00565 4.5e-24 yqzJ
MHPLLIDD_00566 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHPLLIDD_00567 2.6e-140 yqjF S Uncharacterized conserved protein (COG2071)
MHPLLIDD_00568 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MHPLLIDD_00569 3.8e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MHPLLIDD_00570 8.7e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
MHPLLIDD_00572 1.4e-98 yqjB S protein conserved in bacteria
MHPLLIDD_00573 7.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
MHPLLIDD_00574 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MHPLLIDD_00575 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
MHPLLIDD_00576 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
MHPLLIDD_00577 9.3e-77 yqiW S Belongs to the UPF0403 family
MHPLLIDD_00578 9.8e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MHPLLIDD_00579 5.1e-207 norA EGP Major facilitator Superfamily
MHPLLIDD_00580 6.4e-151 bmrR K helix_turn_helix, mercury resistance
MHPLLIDD_00581 5.4e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHPLLIDD_00582 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHPLLIDD_00583 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHPLLIDD_00584 2.8e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHPLLIDD_00585 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
MHPLLIDD_00586 1.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MHPLLIDD_00587 2.3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
MHPLLIDD_00588 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
MHPLLIDD_00589 4e-34 yqzF S Protein of unknown function (DUF2627)
MHPLLIDD_00590 6.9e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MHPLLIDD_00591 2.4e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MHPLLIDD_00592 8.4e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MHPLLIDD_00593 8.8e-212 mmgC I acyl-CoA dehydrogenase
MHPLLIDD_00594 2.3e-156 hbdA 1.1.1.157 I Dehydrogenase
MHPLLIDD_00595 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
MHPLLIDD_00596 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MHPLLIDD_00597 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
MHPLLIDD_00598 5.9e-27
MHPLLIDD_00599 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MHPLLIDD_00601 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MHPLLIDD_00602 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
MHPLLIDD_00603 0.0 recN L May be involved in recombinational repair of damaged DNA
MHPLLIDD_00604 1.7e-78 argR K Regulates arginine biosynthesis genes
MHPLLIDD_00605 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MHPLLIDD_00606 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHPLLIDD_00607 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MHPLLIDD_00608 1.5e-37 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHPLLIDD_00609 1.9e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHPLLIDD_00610 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHPLLIDD_00611 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHPLLIDD_00612 2.1e-67 yqhY S protein conserved in bacteria
MHPLLIDD_00613 3.4e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MHPLLIDD_00614 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHPLLIDD_00615 9.9e-91 spoIIIAH S SpoIIIAH-like protein
MHPLLIDD_00616 2.2e-109 spoIIIAG S stage III sporulation protein AG
MHPLLIDD_00617 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MHPLLIDD_00618 1.3e-197 spoIIIAE S stage III sporulation protein AE
MHPLLIDD_00619 2.3e-58 spoIIIAD S Stage III sporulation protein AD
MHPLLIDD_00620 7.6e-29 spoIIIAC S stage III sporulation protein AC
MHPLLIDD_00621 1.1e-84 spoIIIAB S Stage III sporulation protein
MHPLLIDD_00622 3e-170 spoIIIAA S stage III sporulation protein AA
MHPLLIDD_00623 7.9e-37 yqhV S Protein of unknown function (DUF2619)
MHPLLIDD_00624 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHPLLIDD_00625 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MHPLLIDD_00626 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MHPLLIDD_00627 2.3e-93 yqhR S Conserved membrane protein YqhR
MHPLLIDD_00628 1.4e-173 yqhQ S Protein of unknown function (DUF1385)
MHPLLIDD_00629 2.2e-61 yqhP
MHPLLIDD_00630 3.4e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
MHPLLIDD_00631 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MHPLLIDD_00632 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MHPLLIDD_00633 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
MHPLLIDD_00634 1e-284 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHPLLIDD_00635 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHPLLIDD_00636 5.3e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MHPLLIDD_00637 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHPLLIDD_00638 3.2e-152 yqhG S Bacterial protein YqhG of unknown function
MHPLLIDD_00639 1.2e-24 sinI S Anti-repressor SinI
MHPLLIDD_00640 1e-54 sinR K transcriptional
MHPLLIDD_00641 2.5e-141 tasA S Cell division protein FtsN
MHPLLIDD_00642 2.5e-58 sipW 3.4.21.89 U Signal peptidase
MHPLLIDD_00643 2.8e-113 yqxM
MHPLLIDD_00644 7.3e-54 yqzG S Protein of unknown function (DUF3889)
MHPLLIDD_00645 4.4e-25 yqzE S YqzE-like protein
MHPLLIDD_00646 8.8e-44 S ComG operon protein 7
MHPLLIDD_00647 1.7e-34 comGF U Putative Competence protein ComGF
MHPLLIDD_00648 2e-58 comGE
MHPLLIDD_00649 6.3e-70 gspH NU protein transport across the cell outer membrane
MHPLLIDD_00650 6.8e-47 comGC U Required for transformation and DNA binding
MHPLLIDD_00651 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
MHPLLIDD_00652 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MHPLLIDD_00654 7.2e-175 corA P Mg2 transporter protein
MHPLLIDD_00655 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MHPLLIDD_00656 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHPLLIDD_00658 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
MHPLLIDD_00659 1.8e-37 yqgY S Protein of unknown function (DUF2626)
MHPLLIDD_00660 9.5e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MHPLLIDD_00661 8.9e-23 yqgW S Protein of unknown function (DUF2759)
MHPLLIDD_00662 6.9e-50 yqgV S Thiamine-binding protein
MHPLLIDD_00663 2.7e-199 yqgU
MHPLLIDD_00664 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
MHPLLIDD_00665 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MHPLLIDD_00666 5.2e-181 glcK 2.7.1.2 G Glucokinase
MHPLLIDD_00667 3.1e-33 yqgQ S Protein conserved in bacteria
MHPLLIDD_00668 2.5e-262 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MHPLLIDD_00669 2.5e-09 yqgO
MHPLLIDD_00670 2e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHPLLIDD_00671 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MHPLLIDD_00672 5.1e-201 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
MHPLLIDD_00674 3.5e-50 yqzD
MHPLLIDD_00675 7.3e-72 yqzC S YceG-like family
MHPLLIDD_00676 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHPLLIDD_00677 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHPLLIDD_00678 4.4e-158 pstA P Phosphate transport system permease
MHPLLIDD_00679 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
MHPLLIDD_00680 3.4e-150 pstS P Phosphate
MHPLLIDD_00681 0.0 pbpA 3.4.16.4 M penicillin-binding protein
MHPLLIDD_00682 2.5e-231 yqgE EGP Major facilitator superfamily
MHPLLIDD_00683 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MHPLLIDD_00684 4e-73 yqgC S protein conserved in bacteria
MHPLLIDD_00685 1.5e-130 yqgB S Protein of unknown function (DUF1189)
MHPLLIDD_00686 1.2e-46 yqfZ M LysM domain
MHPLLIDD_00687 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MHPLLIDD_00688 4.3e-62 yqfX S membrane
MHPLLIDD_00689 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MHPLLIDD_00690 1.9e-77 zur P Belongs to the Fur family
MHPLLIDD_00691 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MHPLLIDD_00692 7.9e-36 yqfT S Protein of unknown function (DUF2624)
MHPLLIDD_00693 2.6e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MHPLLIDD_00694 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHPLLIDD_00695 3.5e-12 yqfQ S YqfQ-like protein
MHPLLIDD_00696 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MHPLLIDD_00697 5.3e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHPLLIDD_00698 1.5e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
MHPLLIDD_00699 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
MHPLLIDD_00700 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHPLLIDD_00701 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHPLLIDD_00702 4.5e-88 yaiI S Belongs to the UPF0178 family
MHPLLIDD_00703 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHPLLIDD_00704 4.5e-112 ccpN K CBS domain
MHPLLIDD_00705 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MHPLLIDD_00706 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MHPLLIDD_00707 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
MHPLLIDD_00708 8.4e-19 S YqzL-like protein
MHPLLIDD_00709 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHPLLIDD_00710 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MHPLLIDD_00711 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MHPLLIDD_00712 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHPLLIDD_00713 0.0 yqfF S membrane-associated HD superfamily hydrolase
MHPLLIDD_00715 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
MHPLLIDD_00716 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MHPLLIDD_00717 2.7e-45 yqfC S sporulation protein YqfC
MHPLLIDD_00718 2.4e-21 yqfB
MHPLLIDD_00719 4.3e-122 yqfA S UPF0365 protein
MHPLLIDD_00720 7.7e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MHPLLIDD_00721 2.5e-61 yqeY S Yqey-like protein
MHPLLIDD_00722 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MHPLLIDD_00723 8.2e-158 yqeW P COG1283 Na phosphate symporter
MHPLLIDD_00724 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MHPLLIDD_00725 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHPLLIDD_00726 6e-174 prmA J Methylates ribosomal protein L11
MHPLLIDD_00727 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHPLLIDD_00728 0.0 dnaK O Heat shock 70 kDa protein
MHPLLIDD_00729 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHPLLIDD_00730 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHPLLIDD_00731 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
MHPLLIDD_00732 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHPLLIDD_00733 7.2e-53 yqxA S Protein of unknown function (DUF3679)
MHPLLIDD_00734 4.5e-222 spoIIP M stage II sporulation protein P
MHPLLIDD_00735 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MHPLLIDD_00736 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
MHPLLIDD_00737 5.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
MHPLLIDD_00738 4.1e-15 S YqzM-like protein
MHPLLIDD_00739 0.0 comEC S Competence protein ComEC
MHPLLIDD_00740 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
MHPLLIDD_00741 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
MHPLLIDD_00742 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHPLLIDD_00743 2.9e-139 yqeM Q Methyltransferase
MHPLLIDD_00744 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHPLLIDD_00745 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MHPLLIDD_00746 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHPLLIDD_00747 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MHPLLIDD_00748 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHPLLIDD_00749 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MHPLLIDD_00750 5.3e-95 yqeG S hydrolase of the HAD superfamily
MHPLLIDD_00752 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
MHPLLIDD_00753 1.7e-131 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MHPLLIDD_00754 2.3e-105 yqeD S SNARE associated Golgi protein
MHPLLIDD_00755 1.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MHPLLIDD_00756 2e-132 yqeB
MHPLLIDD_00757 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
MHPLLIDD_00758 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPLLIDD_00759 3.6e-112 tetR3 K Transcriptional regulator
MHPLLIDD_00760 2e-215 mepA V Multidrug transporter MatE
MHPLLIDD_00761 7e-166 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MHPLLIDD_00762 5.4e-112 yrkJ S membrane transporter protein
MHPLLIDD_00763 3.5e-35 yrkI O Belongs to the sulfur carrier protein TusA family
MHPLLIDD_00764 9.3e-206 yrkH P Rhodanese Homology Domain
MHPLLIDD_00765 2.3e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
MHPLLIDD_00766 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
MHPLLIDD_00767 7.8e-39 yrkD S protein conserved in bacteria
MHPLLIDD_00768 5.5e-106 yrkC G Cupin domain
MHPLLIDD_00769 4.2e-147 bltR K helix_turn_helix, mercury resistance
MHPLLIDD_00770 3.9e-210 blt EGP Major facilitator Superfamily
MHPLLIDD_00771 5.9e-82 bltD 2.3.1.57 K FR47-like protein
MHPLLIDD_00772 2.5e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MHPLLIDD_00773 3.9e-16 S YrzO-like protein
MHPLLIDD_00774 1.6e-169 yrdR EG EamA-like transporter family
MHPLLIDD_00775 3e-159 yrdQ K Transcriptional regulator
MHPLLIDD_00776 2.3e-198 trkA P Oxidoreductase
MHPLLIDD_00777 4e-149 czcD P COG1230 Co Zn Cd efflux system component
MHPLLIDD_00778 1.3e-66 yodA S tautomerase
MHPLLIDD_00779 5e-162 gltR K LysR substrate binding domain
MHPLLIDD_00780 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
MHPLLIDD_00781 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
MHPLLIDD_00782 9.6e-138 azlC E AzlC protein
MHPLLIDD_00783 5.3e-78 bkdR K helix_turn_helix ASNC type
MHPLLIDD_00784 1.1e-40 yrdF K ribonuclease inhibitor
MHPLLIDD_00785 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
MHPLLIDD_00786 3.3e-57 S Protein of unknown function (DUF2568)
MHPLLIDD_00787 2.4e-89 yrdA S DinB family
MHPLLIDD_00788 4.2e-166 aadK G Streptomycin adenylyltransferase
MHPLLIDD_00789 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MHPLLIDD_00790 4.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MHPLLIDD_00791 1.6e-123 yrpD S Domain of unknown function, YrpD
MHPLLIDD_00793 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MHPLLIDD_00794 2.4e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
MHPLLIDD_00795 1.3e-187 yrpG C Aldo/keto reductase family
MHPLLIDD_00796 3.4e-223 yraO C Citrate transporter
MHPLLIDD_00797 3.4e-163 yraN K Transcriptional regulator
MHPLLIDD_00798 1.6e-205 yraM S PrpF protein
MHPLLIDD_00800 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MHPLLIDD_00801 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHPLLIDD_00802 3.2e-155 S Alpha beta hydrolase
MHPLLIDD_00803 1.7e-60 T sh3 domain protein
MHPLLIDD_00804 2.4e-61 T sh3 domain protein
MHPLLIDD_00805 1.3e-66 E Glyoxalase-like domain
MHPLLIDD_00806 5.3e-37 yraG
MHPLLIDD_00807 6.4e-63 yraF M Spore coat protein
MHPLLIDD_00808 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHPLLIDD_00809 2.6e-26 yraE
MHPLLIDD_00810 1.1e-49 yraD M Spore coat protein
MHPLLIDD_00811 4.3e-47 yraB K helix_turn_helix, mercury resistance
MHPLLIDD_00812 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
MHPLLIDD_00813 3.2e-200 adhA 1.1.1.1 C alcohol dehydrogenase
MHPLLIDD_00814 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
MHPLLIDD_00815 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MHPLLIDD_00816 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MHPLLIDD_00817 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MHPLLIDD_00818 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
MHPLLIDD_00819 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
MHPLLIDD_00820 0.0 levR K PTS system fructose IIA component
MHPLLIDD_00821 1e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MHPLLIDD_00822 3.6e-106 yrhP E LysE type translocator
MHPLLIDD_00823 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
MHPLLIDD_00824 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MHPLLIDD_00825 3.8e-151 rsiV S Protein of unknown function (DUF3298)
MHPLLIDD_00826 0.0 yrhL I Acyltransferase family
MHPLLIDD_00827 1e-18 yrhK S YrhK-like protein
MHPLLIDD_00828 7.3e-29 S Butirosin biosynthesis protein H, N-terminal
MHPLLIDD_00829 3.9e-11 O Butirosin biosynthesis protein H, N-terminal
MHPLLIDD_00830 1.5e-52 S dehydrogenases and related proteins
MHPLLIDD_00831 6.6e-88 yodQ 3.5.1.16 E Acetylornithine deacetylase
MHPLLIDD_00832 1.2e-100 EF ATP-grasp domain
MHPLLIDD_00833 1.5e-180 hutH 4.3.1.23, 4.3.1.24, 4.3.1.3, 5.4.3.6 E Aromatic amino acid lyase
MHPLLIDD_00834 2e-46 hopR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MHPLLIDD_00835 7.2e-104 Q TIGRFAM amino acid adenylation domain
MHPLLIDD_00836 8.3e-63 S ABC-2 family transporter protein
MHPLLIDD_00837 5.7e-64 S ABC-2 family transporter protein
MHPLLIDD_00838 9.4e-117 S ATPases associated with a variety of cellular activities
MHPLLIDD_00839 2.6e-119 wbpP 5.1.3.2, 5.1.3.7 GM NmrA-like family
MHPLLIDD_00840 4.3e-168 capL C PFAM UDP-glucose GDP-mannose dehydrogenase
MHPLLIDD_00841 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MHPLLIDD_00842 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
MHPLLIDD_00843 7.2e-95 yrhH Q methyltransferase
MHPLLIDD_00846 1.8e-142 focA P Formate nitrite
MHPLLIDD_00847 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
MHPLLIDD_00848 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MHPLLIDD_00849 1.4e-78 yrhD S Protein of unknown function (DUF1641)
MHPLLIDD_00850 4.6e-35 yrhC S YrhC-like protein
MHPLLIDD_00851 1.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MHPLLIDD_00852 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MHPLLIDD_00853 1.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHPLLIDD_00854 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MHPLLIDD_00855 1e-25 yrzA S Protein of unknown function (DUF2536)
MHPLLIDD_00856 2.5e-60 yrrS S Protein of unknown function (DUF1510)
MHPLLIDD_00857 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
MHPLLIDD_00858 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHPLLIDD_00859 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MHPLLIDD_00860 2.7e-246 yegQ O COG0826 Collagenase and related proteases
MHPLLIDD_00861 3.9e-173 yegQ O Peptidase U32
MHPLLIDD_00862 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
MHPLLIDD_00863 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHPLLIDD_00864 1.2e-45 yrzB S Belongs to the UPF0473 family
MHPLLIDD_00865 3e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHPLLIDD_00866 1.7e-41 yrzL S Belongs to the UPF0297 family
MHPLLIDD_00867 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHPLLIDD_00868 2.7e-170 yrrI S AI-2E family transporter
MHPLLIDD_00869 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MHPLLIDD_00870 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
MHPLLIDD_00871 8e-109 gluC P ABC transporter
MHPLLIDD_00872 7.6e-107 glnP P ABC transporter
MHPLLIDD_00873 8e-08 S Protein of unknown function (DUF3918)
MHPLLIDD_00874 9.8e-31 yrzR
MHPLLIDD_00875 2.5e-80 yrrD S protein conserved in bacteria
MHPLLIDD_00876 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MHPLLIDD_00877 1.4e-15 S COG0457 FOG TPR repeat
MHPLLIDD_00878 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHPLLIDD_00879 1.4e-212 iscS 2.8.1.7 E Cysteine desulfurase
MHPLLIDD_00880 1.2e-70 cymR K Transcriptional regulator
MHPLLIDD_00881 4.4e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MHPLLIDD_00882 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MHPLLIDD_00883 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MHPLLIDD_00884 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MHPLLIDD_00886 1.5e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
MHPLLIDD_00887 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHPLLIDD_00888 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHPLLIDD_00889 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHPLLIDD_00890 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MHPLLIDD_00891 3e-48 yrvD S Lipopolysaccharide assembly protein A domain
MHPLLIDD_00892 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
MHPLLIDD_00893 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MHPLLIDD_00894 9.4e-49 yrzD S Post-transcriptional regulator
MHPLLIDD_00895 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHPLLIDD_00896 3e-111 yrbG S membrane
MHPLLIDD_00897 2.2e-73 yrzE S Protein of unknown function (DUF3792)
MHPLLIDD_00898 1.1e-38 yajC U Preprotein translocase subunit YajC
MHPLLIDD_00899 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHPLLIDD_00900 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MHPLLIDD_00901 2.6e-18 yrzS S Protein of unknown function (DUF2905)
MHPLLIDD_00902 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHPLLIDD_00903 3.8e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHPLLIDD_00904 4.8e-93 bofC S BofC C-terminal domain
MHPLLIDD_00905 4.5e-252 csbX EGP Major facilitator Superfamily
MHPLLIDD_00906 4.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MHPLLIDD_00907 6.5e-119 yrzF T serine threonine protein kinase
MHPLLIDD_00909 1.3e-50 S Family of unknown function (DUF5412)
MHPLLIDD_00910 4.5e-261 alsT E Sodium alanine symporter
MHPLLIDD_00911 1e-125 yebC K transcriptional regulatory protein
MHPLLIDD_00912 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHPLLIDD_00913 8.3e-157 safA M spore coat assembly protein SafA
MHPLLIDD_00914 1.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MHPLLIDD_00915 1.9e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MHPLLIDD_00916 2.3e-303 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MHPLLIDD_00917 4.5e-227 nifS 2.8.1.7 E Cysteine desulfurase
MHPLLIDD_00918 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
MHPLLIDD_00919 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
MHPLLIDD_00920 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
MHPLLIDD_00921 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHPLLIDD_00922 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MHPLLIDD_00923 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MHPLLIDD_00924 4.1e-56 ysxB J ribosomal protein
MHPLLIDD_00925 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MHPLLIDD_00926 9.2e-161 spoIVFB S Stage IV sporulation protein
MHPLLIDD_00927 9.3e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MHPLLIDD_00928 4.7e-143 minD D Belongs to the ParA family
MHPLLIDD_00929 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MHPLLIDD_00930 1.4e-84 mreD M shape-determining protein
MHPLLIDD_00931 2.8e-157 mreC M Involved in formation and maintenance of cell shape
MHPLLIDD_00932 1.8e-184 mreB D Rod shape-determining protein MreB
MHPLLIDD_00933 1.3e-125 radC E Belongs to the UPF0758 family
MHPLLIDD_00934 8.3e-102 maf D septum formation protein Maf
MHPLLIDD_00935 8.4e-166 spoIIB S Sporulation related domain
MHPLLIDD_00936 8.3e-126 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MHPLLIDD_00937 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MHPLLIDD_00938 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHPLLIDD_00939 1.6e-25
MHPLLIDD_00940 1.7e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MHPLLIDD_00941 2.2e-222 spoVID M stage VI sporulation protein D
MHPLLIDD_00942 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MHPLLIDD_00943 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
MHPLLIDD_00944 7.1e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MHPLLIDD_00945 9.6e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MHPLLIDD_00946 3.6e-146 hemX O cytochrome C
MHPLLIDD_00947 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MHPLLIDD_00948 1.4e-89 ysxD
MHPLLIDD_00949 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MHPLLIDD_00950 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MHPLLIDD_00951 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MHPLLIDD_00952 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHPLLIDD_00953 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHPLLIDD_00954 2.3e-187 ysoA H Tetratricopeptide repeat
MHPLLIDD_00955 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHPLLIDD_00956 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHPLLIDD_00957 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MHPLLIDD_00958 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MHPLLIDD_00959 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MHPLLIDD_00960 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
MHPLLIDD_00961 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MHPLLIDD_00963 7.6e-82 ysnE K acetyltransferase
MHPLLIDD_00964 9.1e-134 ysnF S protein conserved in bacteria
MHPLLIDD_00966 1.4e-92 ysnB S Phosphoesterase
MHPLLIDD_00967 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MHPLLIDD_00968 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MHPLLIDD_00969 2.9e-196 gerM S COG5401 Spore germination protein
MHPLLIDD_00970 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MHPLLIDD_00971 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
MHPLLIDD_00972 3.3e-30 gerE K Transcriptional regulator
MHPLLIDD_00973 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
MHPLLIDD_00974 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MHPLLIDD_00975 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MHPLLIDD_00976 2.4e-107 sdhC C succinate dehydrogenase
MHPLLIDD_00977 1.2e-79 yslB S Protein of unknown function (DUF2507)
MHPLLIDD_00978 3.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MHPLLIDD_00979 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHPLLIDD_00980 2e-52 trxA O Belongs to the thioredoxin family
MHPLLIDD_00981 5.7e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
MHPLLIDD_00983 2.1e-177 etfA C Electron transfer flavoprotein
MHPLLIDD_00984 4.5e-135 etfB C Electron transfer flavoprotein
MHPLLIDD_00985 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MHPLLIDD_00986 2.7e-100 fadR K Transcriptional regulator
MHPLLIDD_00987 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHPLLIDD_00988 7.3e-68 yshE S membrane
MHPLLIDD_00989 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHPLLIDD_00990 0.0 polX L COG1796 DNA polymerase IV (family X)
MHPLLIDD_00991 1.3e-85 cvpA S membrane protein, required for colicin V production
MHPLLIDD_00992 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MHPLLIDD_00993 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHPLLIDD_00994 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHPLLIDD_00995 2.3e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHPLLIDD_00996 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHPLLIDD_00997 5.8e-32 sspI S Belongs to the SspI family
MHPLLIDD_00998 9.2e-206 ysfB KT regulator
MHPLLIDD_00999 8.2e-260 glcD 1.1.3.15 C Glycolate oxidase subunit
MHPLLIDD_01000 5.8e-255 glcF C Glycolate oxidase
MHPLLIDD_01001 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
MHPLLIDD_01002 0.0 cstA T Carbon starvation protein
MHPLLIDD_01003 1.7e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
MHPLLIDD_01004 3.8e-143 araQ G transport system permease
MHPLLIDD_01005 4.2e-167 araP G carbohydrate transport
MHPLLIDD_01006 2e-252 araN G carbohydrate transport
MHPLLIDD_01007 1.8e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MHPLLIDD_01008 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MHPLLIDD_01009 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MHPLLIDD_01010 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
MHPLLIDD_01011 3.9e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MHPLLIDD_01012 1.2e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MHPLLIDD_01013 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
MHPLLIDD_01014 9.2e-68 ysdB S Sigma-w pathway protein YsdB
MHPLLIDD_01015 7.5e-45 ysdA S Membrane
MHPLLIDD_01016 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHPLLIDD_01017 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MHPLLIDD_01018 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHPLLIDD_01020 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MHPLLIDD_01021 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MHPLLIDD_01022 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
MHPLLIDD_01023 0.0 lytS 2.7.13.3 T Histidine kinase
MHPLLIDD_01024 1.5e-149 ysaA S HAD-hyrolase-like
MHPLLIDD_01025 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHPLLIDD_01026 3.8e-159 ytxC S YtxC-like family
MHPLLIDD_01027 4.9e-111 ytxB S SNARE associated Golgi protein
MHPLLIDD_01028 3e-173 dnaI L Primosomal protein DnaI
MHPLLIDD_01029 3.5e-266 dnaB L Membrane attachment protein
MHPLLIDD_01030 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHPLLIDD_01031 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MHPLLIDD_01032 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHPLLIDD_01033 9.9e-67 ytcD K Transcriptional regulator
MHPLLIDD_01034 4.9e-205 ytbD EGP Major facilitator Superfamily
MHPLLIDD_01035 8.9e-161 ytbE S reductase
MHPLLIDD_01036 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHPLLIDD_01037 1.1e-107 ytaF P Probably functions as a manganese efflux pump
MHPLLIDD_01038 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHPLLIDD_01039 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHPLLIDD_01040 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MHPLLIDD_01041 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPLLIDD_01042 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MHPLLIDD_01043 1.8e-242 icd 1.1.1.42 C isocitrate
MHPLLIDD_01044 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
MHPLLIDD_01045 4.7e-71 yeaL S membrane
MHPLLIDD_01046 9.9e-192 ytvI S sporulation integral membrane protein YtvI
MHPLLIDD_01047 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MHPLLIDD_01048 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MHPLLIDD_01049 7.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHPLLIDD_01050 8.1e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MHPLLIDD_01051 3.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHPLLIDD_01052 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
MHPLLIDD_01053 0.0 dnaE 2.7.7.7 L DNA polymerase
MHPLLIDD_01054 3.2e-56 ytrH S Sporulation protein YtrH
MHPLLIDD_01055 8.2e-69 ytrI
MHPLLIDD_01056 9.2e-29
MHPLLIDD_01057 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MHPLLIDD_01058 2.4e-47 ytpI S YtpI-like protein
MHPLLIDD_01059 8e-241 ytoI K transcriptional regulator containing CBS domains
MHPLLIDD_01060 1.2e-158 ytnM S membrane transporter protein
MHPLLIDD_01061 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
MHPLLIDD_01062 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
MHPLLIDD_01063 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHPLLIDD_01064 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
MHPLLIDD_01065 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHPLLIDD_01066 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MHPLLIDD_01067 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
MHPLLIDD_01068 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
MHPLLIDD_01069 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
MHPLLIDD_01070 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
MHPLLIDD_01071 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
MHPLLIDD_01072 2.9e-173 ytlI K LysR substrate binding domain
MHPLLIDD_01073 1.7e-130 ytkL S Belongs to the UPF0173 family
MHPLLIDD_01074 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPLLIDD_01076 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
MHPLLIDD_01077 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHPLLIDD_01078 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MHPLLIDD_01079 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHPLLIDD_01080 7e-165 ytxK 2.1.1.72 L DNA methylase
MHPLLIDD_01081 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MHPLLIDD_01082 8.7e-70 ytfJ S Sporulation protein YtfJ
MHPLLIDD_01083 5.6e-116 ytfI S Protein of unknown function (DUF2953)
MHPLLIDD_01084 1.3e-87 yteJ S RDD family
MHPLLIDD_01085 7.1e-181 sppA OU signal peptide peptidase SppA
MHPLLIDD_01086 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHPLLIDD_01087 0.0 ytcJ S amidohydrolase
MHPLLIDD_01088 5.9e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHPLLIDD_01089 2e-29 sspB S spore protein
MHPLLIDD_01090 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHPLLIDD_01091 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
MHPLLIDD_01092 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
MHPLLIDD_01093 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHPLLIDD_01094 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MHPLLIDD_01095 3.4e-109 yttP K Transcriptional regulator
MHPLLIDD_01096 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
MHPLLIDD_01097 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MHPLLIDD_01098 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHPLLIDD_01100 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHPLLIDD_01101 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHPLLIDD_01102 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MHPLLIDD_01103 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
MHPLLIDD_01104 1.9e-225 acuC BQ histone deacetylase
MHPLLIDD_01105 1.4e-125 motS N Flagellar motor protein
MHPLLIDD_01106 7.1e-147 motA N flagellar motor
MHPLLIDD_01107 1.7e-182 ccpA K catabolite control protein A
MHPLLIDD_01108 1.4e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MHPLLIDD_01109 1.7e-54 ytxJ O Protein of unknown function (DUF2847)
MHPLLIDD_01110 1.9e-16 ytxH S COG4980 Gas vesicle protein
MHPLLIDD_01111 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHPLLIDD_01112 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MHPLLIDD_01113 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MHPLLIDD_01114 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHPLLIDD_01115 9.8e-149 ytpQ S Belongs to the UPF0354 family
MHPLLIDD_01116 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MHPLLIDD_01117 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MHPLLIDD_01118 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MHPLLIDD_01119 1.1e-50 ytzB S small secreted protein
MHPLLIDD_01120 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
MHPLLIDD_01121 1.8e-148 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MHPLLIDD_01122 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHPLLIDD_01123 2e-45 ytzH S YtzH-like protein
MHPLLIDD_01124 1e-150 ytmP 2.7.1.89 M Phosphotransferase
MHPLLIDD_01125 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MHPLLIDD_01126 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MHPLLIDD_01127 1.3e-165 ytlQ
MHPLLIDD_01128 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MHPLLIDD_01129 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MHPLLIDD_01130 7.1e-272 pepV 3.5.1.18 E Dipeptidase
MHPLLIDD_01131 7.2e-226 pbuO S permease
MHPLLIDD_01132 5.3e-204 ythQ U Bacterial ABC transporter protein EcsB
MHPLLIDD_01133 3.6e-131 ythP V ABC transporter
MHPLLIDD_01134 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MHPLLIDD_01135 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MHPLLIDD_01136 1.2e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHPLLIDD_01137 1.5e-230 ytfP S HI0933-like protein
MHPLLIDD_01138 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MHPLLIDD_01139 3.1e-26 yteV S Sporulation protein Cse60
MHPLLIDD_01140 4.8e-117 yteU S Integral membrane protein
MHPLLIDD_01141 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
MHPLLIDD_01142 4.6e-73 yteS G transport
MHPLLIDD_01143 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MHPLLIDD_01144 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MHPLLIDD_01145 0.0 ytdP K Transcriptional regulator
MHPLLIDD_01146 1.8e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
MHPLLIDD_01147 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
MHPLLIDD_01148 1.2e-135 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
MHPLLIDD_01149 1.7e-221 bioI 1.14.14.46 C Cytochrome P450
MHPLLIDD_01150 5.4e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MHPLLIDD_01151 1.9e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MHPLLIDD_01152 1.8e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MHPLLIDD_01153 3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MHPLLIDD_01154 3.1e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MHPLLIDD_01155 7.8e-171 ytaP S Acetyl xylan esterase (AXE1)
MHPLLIDD_01156 1.5e-189 msmR K Transcriptional regulator
MHPLLIDD_01157 1.9e-247 msmE G Bacterial extracellular solute-binding protein
MHPLLIDD_01158 1.4e-167 amyD P ABC transporter
MHPLLIDD_01159 1.1e-142 amyC P ABC transporter (permease)
MHPLLIDD_01160 5.8e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MHPLLIDD_01161 2.1e-51 ytwF P Sulfurtransferase
MHPLLIDD_01162 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHPLLIDD_01163 7.7e-55 ytvB S Protein of unknown function (DUF4257)
MHPLLIDD_01164 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MHPLLIDD_01165 7.3e-209 yttB EGP Major facilitator Superfamily
MHPLLIDD_01166 1.3e-41 yttA 2.7.13.3 S Pfam Transposase IS66
MHPLLIDD_01167 0.0 bceB V ABC transporter (permease)
MHPLLIDD_01168 1.1e-138 bceA V ABC transporter, ATP-binding protein
MHPLLIDD_01169 1.8e-184 T PhoQ Sensor
MHPLLIDD_01170 1.1e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPLLIDD_01171 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
MHPLLIDD_01172 3.1e-127 ytrE V ABC transporter, ATP-binding protein
MHPLLIDD_01173 5.9e-148
MHPLLIDD_01174 8.3e-166 P ABC-2 family transporter protein
MHPLLIDD_01175 4.2e-161 ytrB P abc transporter atp-binding protein
MHPLLIDD_01176 5.1e-66 ytrA K GntR family transcriptional regulator
MHPLLIDD_01178 6.7e-41 ytzC S Protein of unknown function (DUF2524)
MHPLLIDD_01179 2.1e-190 yhcC S Fe-S oxidoreductase
MHPLLIDD_01180 3.3e-106 ytqB J Putative rRNA methylase
MHPLLIDD_01181 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MHPLLIDD_01182 5.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
MHPLLIDD_01183 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MHPLLIDD_01184 1.1e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
MHPLLIDD_01185 0.0 asnB 6.3.5.4 E Asparagine synthase
MHPLLIDD_01186 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHPLLIDD_01187 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MHPLLIDD_01188 1.2e-38 ytmB S Protein of unknown function (DUF2584)
MHPLLIDD_01189 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MHPLLIDD_01190 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MHPLLIDD_01191 1.4e-144 ytlC P ABC transporter
MHPLLIDD_01192 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHPLLIDD_01193 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MHPLLIDD_01194 5.4e-63 ytkC S Bacteriophage holin family
MHPLLIDD_01195 2.1e-76 dps P Belongs to the Dps family
MHPLLIDD_01197 2.4e-72 ytkA S YtkA-like
MHPLLIDD_01198 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHPLLIDD_01199 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MHPLLIDD_01200 3.6e-41 rpmE2 J Ribosomal protein L31
MHPLLIDD_01201 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
MHPLLIDD_01202 1.8e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MHPLLIDD_01203 1.1e-24 S Domain of Unknown Function (DUF1540)
MHPLLIDD_01204 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MHPLLIDD_01205 8.8e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MHPLLIDD_01206 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MHPLLIDD_01207 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
MHPLLIDD_01208 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MHPLLIDD_01209 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MHPLLIDD_01210 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MHPLLIDD_01211 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MHPLLIDD_01212 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MHPLLIDD_01213 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
MHPLLIDD_01214 2.6e-132 dksA T COG1734 DnaK suppressor protein
MHPLLIDD_01215 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
MHPLLIDD_01216 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHPLLIDD_01217 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
MHPLLIDD_01218 3.6e-235 ytcC M Glycosyltransferase Family 4
MHPLLIDD_01220 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
MHPLLIDD_01221 1.8e-217 cotSA M Glycosyl transferases group 1
MHPLLIDD_01222 1.8e-206 cotI S Spore coat protein
MHPLLIDD_01223 9.9e-77 tspO T membrane
MHPLLIDD_01224 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MHPLLIDD_01225 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MHPLLIDD_01226 6.4e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
MHPLLIDD_01227 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MHPLLIDD_01228 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MHPLLIDD_01237 7.8e-08
MHPLLIDD_01238 1.3e-09
MHPLLIDD_01245 2e-08
MHPLLIDD_01250 3.4e-39 S COG NOG14552 non supervised orthologous group
MHPLLIDD_01251 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
MHPLLIDD_01252 1.4e-92 M1-753 M FR47-like protein
MHPLLIDD_01253 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
MHPLLIDD_01254 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MHPLLIDD_01255 3.9e-84 yuaE S DinB superfamily
MHPLLIDD_01256 7.4e-106 yuaD
MHPLLIDD_01257 1.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
MHPLLIDD_01258 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MHPLLIDD_01259 2.7e-94 yuaC K Belongs to the GbsR family
MHPLLIDD_01260 2.2e-91 yuaB
MHPLLIDD_01261 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
MHPLLIDD_01262 1.6e-236 ktrB P Potassium
MHPLLIDD_01263 1e-38 yiaA S yiaA/B two helix domain
MHPLLIDD_01264 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHPLLIDD_01265 4.9e-274 yubD P Major Facilitator Superfamily
MHPLLIDD_01266 6.4e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
MHPLLIDD_01268 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHPLLIDD_01269 3.7e-189 yubA S transporter activity
MHPLLIDD_01270 9.7e-183 ygjR S Oxidoreductase
MHPLLIDD_01271 9.1e-250 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MHPLLIDD_01272 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MHPLLIDD_01273 3.6e-274 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MHPLLIDD_01274 3.8e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
MHPLLIDD_01275 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
MHPLLIDD_01277 2.1e-237 mcpA NT chemotaxis protein
MHPLLIDD_01278 8.5e-295 mcpA NT chemotaxis protein
MHPLLIDD_01279 6.9e-220 mcpA NT chemotaxis protein
MHPLLIDD_01280 9.3e-225 mcpA NT chemotaxis protein
MHPLLIDD_01281 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
MHPLLIDD_01282 2.3e-35
MHPLLIDD_01283 2.1e-72 yugU S Uncharacterised protein family UPF0047
MHPLLIDD_01284 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MHPLLIDD_01285 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
MHPLLIDD_01286 1.4e-116 yugP S Zn-dependent protease
MHPLLIDD_01287 2.3e-38
MHPLLIDD_01288 1.1e-53 mstX S Membrane-integrating protein Mistic
MHPLLIDD_01289 2.2e-182 yugO P COG1226 Kef-type K transport systems
MHPLLIDD_01290 1.3e-72 yugN S YugN-like family
MHPLLIDD_01292 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
MHPLLIDD_01293 2.8e-229 yugK C Dehydrogenase
MHPLLIDD_01294 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MHPLLIDD_01295 1.1e-34 yuzA S Domain of unknown function (DUF378)
MHPLLIDD_01296 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MHPLLIDD_01297 2.1e-199 yugH 2.6.1.1 E Aminotransferase
MHPLLIDD_01298 1.6e-85 alaR K Transcriptional regulator
MHPLLIDD_01299 4.9e-156 yugF I Hydrolase
MHPLLIDD_01300 4.6e-39 yugE S Domain of unknown function (DUF1871)
MHPLLIDD_01301 2.1e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MHPLLIDD_01302 3.9e-232 T PhoQ Sensor
MHPLLIDD_01303 7.4e-70 kapB G Kinase associated protein B
MHPLLIDD_01304 1.9e-115 kapD L the KinA pathway to sporulation
MHPLLIDD_01306 2.1e-183 yuxJ EGP Major facilitator Superfamily
MHPLLIDD_01307 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
MHPLLIDD_01308 6.3e-75 yuxK S protein conserved in bacteria
MHPLLIDD_01309 6.3e-78 yufK S Family of unknown function (DUF5366)
MHPLLIDD_01310 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MHPLLIDD_01311 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
MHPLLIDD_01312 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MHPLLIDD_01313 2.3e-271 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MHPLLIDD_01314 1.9e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
MHPLLIDD_01315 1.2e-166 yufQ S Belongs to the binding-protein-dependent transport system permease family
MHPLLIDD_01316 1.2e-231 maeN C COG3493 Na citrate symporter
MHPLLIDD_01317 3.2e-14
MHPLLIDD_01318 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MHPLLIDD_01319 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHPLLIDD_01320 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHPLLIDD_01321 6.4e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHPLLIDD_01322 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHPLLIDD_01323 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHPLLIDD_01324 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MHPLLIDD_01325 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
MHPLLIDD_01326 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHPLLIDD_01327 0.0 comP 2.7.13.3 T Histidine kinase
MHPLLIDD_01329 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
MHPLLIDD_01332 3.2e-22 yuzC
MHPLLIDD_01333 1.8e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
MHPLLIDD_01334 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHPLLIDD_01335 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
MHPLLIDD_01336 7.9e-67 yueI S Protein of unknown function (DUF1694)
MHPLLIDD_01337 2.8e-38 yueH S YueH-like protein
MHPLLIDD_01338 2.1e-32 yueG S Spore germination protein gerPA/gerPF
MHPLLIDD_01339 1.9e-190 yueF S transporter activity
MHPLLIDD_01340 6.1e-72 S Protein of unknown function (DUF2283)
MHPLLIDD_01341 2.9e-24 S Protein of unknown function (DUF2642)
MHPLLIDD_01342 4.8e-96 yueE S phosphohydrolase
MHPLLIDD_01343 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPLLIDD_01344 6.6e-65 yueC S Family of unknown function (DUF5383)
MHPLLIDD_01345 0.0 esaA S type VII secretion protein EsaA
MHPLLIDD_01346 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MHPLLIDD_01347 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
MHPLLIDD_01348 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
MHPLLIDD_01349 2.8e-45 esxA S Belongs to the WXG100 family
MHPLLIDD_01350 6.5e-229 yukF QT Transcriptional regulator
MHPLLIDD_01351 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MHPLLIDD_01352 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
MHPLLIDD_01353 3.8e-36 mbtH S MbtH-like protein
MHPLLIDD_01354 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPLLIDD_01355 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
MHPLLIDD_01356 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
MHPLLIDD_01357 6.6e-226 entC 5.4.4.2 HQ Isochorismate synthase
MHPLLIDD_01358 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPLLIDD_01359 1.3e-167 besA S Putative esterase
MHPLLIDD_01360 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
MHPLLIDD_01361 4.4e-93 bioY S Biotin biosynthesis protein
MHPLLIDD_01362 3.9e-211 yuiF S antiporter
MHPLLIDD_01363 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MHPLLIDD_01364 1.2e-77 yuiD S protein conserved in bacteria
MHPLLIDD_01365 9.5e-118 yuiC S protein conserved in bacteria
MHPLLIDD_01366 8.4e-27 yuiB S Putative membrane protein
MHPLLIDD_01367 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
MHPLLIDD_01368 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
MHPLLIDD_01370 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHPLLIDD_01371 1e-116 paiB K Putative FMN-binding domain
MHPLLIDD_01372 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHPLLIDD_01373 3.7e-63 erpA S Belongs to the HesB IscA family
MHPLLIDD_01374 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHPLLIDD_01375 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHPLLIDD_01376 3.2e-39 yuzB S Belongs to the UPF0349 family
MHPLLIDD_01377 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
MHPLLIDD_01378 3.5e-57 yuzD S protein conserved in bacteria
MHPLLIDD_01379 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
MHPLLIDD_01380 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
MHPLLIDD_01381 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHPLLIDD_01382 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MHPLLIDD_01383 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
MHPLLIDD_01384 2e-199 yutH S Spore coat protein
MHPLLIDD_01385 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MHPLLIDD_01386 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHPLLIDD_01387 1e-75 yutE S Protein of unknown function DUF86
MHPLLIDD_01388 9.7e-48 yutD S protein conserved in bacteria
MHPLLIDD_01389 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHPLLIDD_01390 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MHPLLIDD_01391 4.5e-196 lytH M Peptidase, M23
MHPLLIDD_01392 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
MHPLLIDD_01393 4.8e-48 yunC S Domain of unknown function (DUF1805)
MHPLLIDD_01394 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MHPLLIDD_01395 2e-141 yunE S membrane transporter protein
MHPLLIDD_01396 1.6e-170 yunF S Protein of unknown function DUF72
MHPLLIDD_01397 3e-62 yunG
MHPLLIDD_01398 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MHPLLIDD_01399 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
MHPLLIDD_01400 2.1e-236 pbuX F Permease family
MHPLLIDD_01401 1.3e-222 pbuX F xanthine
MHPLLIDD_01402 7.3e-283 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MHPLLIDD_01403 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MHPLLIDD_01404 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MHPLLIDD_01405 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MHPLLIDD_01406 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MHPLLIDD_01407 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
MHPLLIDD_01408 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MHPLLIDD_01410 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MHPLLIDD_01411 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MHPLLIDD_01412 2.4e-169 bsn L Ribonuclease
MHPLLIDD_01413 1.2e-205 msmX P Belongs to the ABC transporter superfamily
MHPLLIDD_01414 1.1e-135 yurK K UTRA
MHPLLIDD_01415 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
MHPLLIDD_01416 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
MHPLLIDD_01417 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
MHPLLIDD_01418 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
MHPLLIDD_01419 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MHPLLIDD_01420 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
MHPLLIDD_01421 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MHPLLIDD_01423 1e-41
MHPLLIDD_01424 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPLLIDD_01425 3.5e-271 sufB O FeS cluster assembly
MHPLLIDD_01426 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MHPLLIDD_01427 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHPLLIDD_01428 1.4e-245 sufD O assembly protein SufD
MHPLLIDD_01429 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MHPLLIDD_01430 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MHPLLIDD_01431 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
MHPLLIDD_01432 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
MHPLLIDD_01433 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHPLLIDD_01434 2.4e-56 yusD S SCP-2 sterol transfer family
MHPLLIDD_01435 5.6e-55 traF CO Thioredoxin
MHPLLIDD_01436 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
MHPLLIDD_01437 1.1e-39 yusG S Protein of unknown function (DUF2553)
MHPLLIDD_01438 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MHPLLIDD_01439 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
MHPLLIDD_01440 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MHPLLIDD_01441 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
MHPLLIDD_01442 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MHPLLIDD_01443 8.1e-09 S YuzL-like protein
MHPLLIDD_01444 7.1e-164 fadM E Proline dehydrogenase
MHPLLIDD_01445 5.1e-40
MHPLLIDD_01446 5.4e-53 yusN M Coat F domain
MHPLLIDD_01447 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
MHPLLIDD_01448 3.2e-292 yusP P Major facilitator superfamily
MHPLLIDD_01449 2.7e-64 yusQ S Tautomerase enzyme
MHPLLIDD_01450 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPLLIDD_01451 5.7e-158 yusT K LysR substrate binding domain
MHPLLIDD_01452 3.8e-47 yusU S Protein of unknown function (DUF2573)
MHPLLIDD_01453 1e-153 yusV 3.6.3.34 HP ABC transporter
MHPLLIDD_01454 2.5e-66 S YusW-like protein
MHPLLIDD_01455 1.9e-301 pepF2 E COG1164 Oligoendopeptidase F
MHPLLIDD_01456 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPLLIDD_01457 1.2e-79 dps P Ferritin-like domain
MHPLLIDD_01458 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHPLLIDD_01459 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPLLIDD_01460 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
MHPLLIDD_01461 4.3e-158 yuxN K Transcriptional regulator
MHPLLIDD_01462 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHPLLIDD_01463 2.3e-24 S Protein of unknown function (DUF3970)
MHPLLIDD_01464 1.4e-246 gerAA EG Spore germination protein
MHPLLIDD_01465 9.1e-198 gerAB E Spore germination protein
MHPLLIDD_01466 3.3e-187 gerAC S Spore germination B3/ GerAC like, C-terminal
MHPLLIDD_01467 8.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHPLLIDD_01468 3.5e-186 vraS 2.7.13.3 T Histidine kinase
MHPLLIDD_01469 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MHPLLIDD_01470 2.3e-127 liaG S Putative adhesin
MHPLLIDD_01471 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MHPLLIDD_01472 5.6e-62 liaI S membrane
MHPLLIDD_01473 1.4e-226 yvqJ EGP Major facilitator Superfamily
MHPLLIDD_01474 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
MHPLLIDD_01475 1.1e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MHPLLIDD_01476 1.6e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPLLIDD_01477 1.9e-167 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MHPLLIDD_01478 2.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPLLIDD_01479 2.9e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
MHPLLIDD_01480 0.0 T PhoQ Sensor
MHPLLIDD_01481 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPLLIDD_01482 3.6e-22
MHPLLIDD_01483 9.5e-98 yvrI K RNA polymerase
MHPLLIDD_01484 2.4e-19 S YvrJ protein family
MHPLLIDD_01485 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
MHPLLIDD_01486 3.8e-64 yvrL S Regulatory protein YrvL
MHPLLIDD_01487 3.4e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
MHPLLIDD_01488 2.1e-123 macB V ABC transporter, ATP-binding protein
MHPLLIDD_01489 2.6e-174 M Efflux transporter rnd family, mfp subunit
MHPLLIDD_01490 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
MHPLLIDD_01491 3.4e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPLLIDD_01492 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPLLIDD_01493 7.6e-177 fhuD P ABC transporter
MHPLLIDD_01495 4.9e-236 yvsH E Arginine ornithine antiporter
MHPLLIDD_01496 6.5e-16 S Small spore protein J (Spore_SspJ)
MHPLLIDD_01497 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
MHPLLIDD_01498 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MHPLLIDD_01499 1.3e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
MHPLLIDD_01500 1e-134 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MHPLLIDD_01501 3.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
MHPLLIDD_01502 2.2e-156 yvgN S reductase
MHPLLIDD_01503 2.1e-85 yvgO
MHPLLIDD_01504 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MHPLLIDD_01505 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MHPLLIDD_01506 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MHPLLIDD_01507 0.0 helD 3.6.4.12 L DNA helicase
MHPLLIDD_01509 2.7e-106 yvgT S membrane
MHPLLIDD_01510 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
MHPLLIDD_01511 1.6e-104 bdbD O Thioredoxin
MHPLLIDD_01512 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MHPLLIDD_01513 0.0 copA 3.6.3.54 P P-type ATPase
MHPLLIDD_01514 1.5e-29 copZ P Copper resistance protein CopZ
MHPLLIDD_01515 2.2e-48 csoR S transcriptional
MHPLLIDD_01516 3.1e-195 yvaA 1.1.1.371 S Oxidoreductase
MHPLLIDD_01517 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHPLLIDD_01518 0.0 yvaC S Fusaric acid resistance protein-like
MHPLLIDD_01519 1.3e-72 yvaD S Family of unknown function (DUF5360)
MHPLLIDD_01520 6.3e-55 yvaE P Small Multidrug Resistance protein
MHPLLIDD_01521 4.1e-101 K Bacterial regulatory proteins, tetR family
MHPLLIDD_01522 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPLLIDD_01524 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MHPLLIDD_01525 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MHPLLIDD_01526 5.6e-143 est 3.1.1.1 S Carboxylesterase
MHPLLIDD_01527 2.4e-23 secG U Preprotein translocase subunit SecG
MHPLLIDD_01528 3.7e-153 yvaM S Serine aminopeptidase, S33
MHPLLIDD_01529 7.5e-36 yvzC K Transcriptional
MHPLLIDD_01530 4e-69 K transcriptional
MHPLLIDD_01531 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
MHPLLIDD_01532 2.2e-54 yodB K transcriptional
MHPLLIDD_01533 1.1e-213 NT chemotaxis protein
MHPLLIDD_01534 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MHPLLIDD_01535 8e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHPLLIDD_01536 5.6e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MHPLLIDD_01537 2.8e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHPLLIDD_01538 3.3e-60 yvbF K Belongs to the GbsR family
MHPLLIDD_01539 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MHPLLIDD_01540 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHPLLIDD_01541 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MHPLLIDD_01542 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHPLLIDD_01543 3.5e-97 yvbF K Belongs to the GbsR family
MHPLLIDD_01544 2.7e-101 yvbG U UPF0056 membrane protein
MHPLLIDD_01545 8.6e-113 yvbH S YvbH-like oligomerisation region
MHPLLIDD_01546 1.3e-120 exoY M Membrane
MHPLLIDD_01547 0.0 tcaA S response to antibiotic
MHPLLIDD_01548 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
MHPLLIDD_01549 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHPLLIDD_01550 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MHPLLIDD_01551 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHPLLIDD_01552 3.8e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MHPLLIDD_01553 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHPLLIDD_01554 2.6e-183 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHPLLIDD_01555 1.6e-252 araE EGP Major facilitator Superfamily
MHPLLIDD_01556 5.5e-203 araR K transcriptional
MHPLLIDD_01557 4.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHPLLIDD_01558 5.1e-159 yvbU K Transcriptional regulator
MHPLLIDD_01559 7.2e-156 yvbV EG EamA-like transporter family
MHPLLIDD_01560 3.7e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
MHPLLIDD_01561 2.6e-194 yvbX S Glycosyl hydrolase
MHPLLIDD_01562 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHPLLIDD_01563 1.7e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MHPLLIDD_01564 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHPLLIDD_01565 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHPLLIDD_01566 1.6e-194 desK 2.7.13.3 T Histidine kinase
MHPLLIDD_01567 6.9e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
MHPLLIDD_01568 1.7e-157 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
MHPLLIDD_01569 6.4e-156 rsbQ S Alpha/beta hydrolase family
MHPLLIDD_01570 3.2e-196 rsbU 3.1.3.3 T response regulator
MHPLLIDD_01571 2.3e-248 galA 3.2.1.89 G arabinogalactan
MHPLLIDD_01572 0.0 lacA 3.2.1.23 G beta-galactosidase
MHPLLIDD_01573 3.2e-150 ganQ P transport
MHPLLIDD_01574 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
MHPLLIDD_01575 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
MHPLLIDD_01576 1.8e-184 lacR K Transcriptional regulator
MHPLLIDD_01577 2.7e-113 yvfI K COG2186 Transcriptional regulators
MHPLLIDD_01578 2.6e-308 yvfH C L-lactate permease
MHPLLIDD_01579 2.3e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MHPLLIDD_01580 1e-31 yvfG S YvfG protein
MHPLLIDD_01581 1.7e-187 yvfF GM Exopolysaccharide biosynthesis protein
MHPLLIDD_01582 2.5e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
MHPLLIDD_01583 1e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
MHPLLIDD_01584 1.1e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MHPLLIDD_01585 1.8e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHPLLIDD_01586 1.3e-193 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
MHPLLIDD_01587 9.5e-200 epsI GM pyruvyl transferase
MHPLLIDD_01588 4.4e-194 epsH GT2 S Glycosyltransferase like family 2
MHPLLIDD_01589 7e-206 epsG S EpsG family
MHPLLIDD_01590 8.4e-218 epsF GT4 M Glycosyl transferases group 1
MHPLLIDD_01591 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MHPLLIDD_01592 1.2e-221 epsD GT4 M Glycosyl transferase 4-like
MHPLLIDD_01593 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MHPLLIDD_01594 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
MHPLLIDD_01595 4e-122 ywqC M biosynthesis protein
MHPLLIDD_01596 1.4e-75 slr K transcriptional
MHPLLIDD_01597 1.6e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MHPLLIDD_01599 5.1e-92 padC Q Phenolic acid decarboxylase
MHPLLIDD_01600 3.8e-73 MA20_18690 S Protein of unknown function (DUF3237)
MHPLLIDD_01601 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MHPLLIDD_01602 3.2e-261 pbpE V Beta-lactamase
MHPLLIDD_01603 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
MHPLLIDD_01604 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MHPLLIDD_01605 1.8e-295 yveA E amino acid
MHPLLIDD_01606 2.6e-106 yvdT K Transcriptional regulator
MHPLLIDD_01607 1.9e-50 ykkC P Small Multidrug Resistance protein
MHPLLIDD_01608 4.1e-50 sugE P Small Multidrug Resistance protein
MHPLLIDD_01609 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
MHPLLIDD_01610 1.1e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
MHPLLIDD_01611 2.8e-182 S Patatin-like phospholipase
MHPLLIDD_01613 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHPLLIDD_01614 2.8e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MHPLLIDD_01615 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MHPLLIDD_01616 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MHPLLIDD_01617 5e-154 malA S Protein of unknown function (DUF1189)
MHPLLIDD_01618 3.9e-148 malD P transport
MHPLLIDD_01619 5.9e-244 malC P COG1175 ABC-type sugar transport systems, permease components
MHPLLIDD_01620 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
MHPLLIDD_01621 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MHPLLIDD_01622 3.6e-174 yvdE K Transcriptional regulator
MHPLLIDD_01623 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
MHPLLIDD_01624 2.6e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
MHPLLIDD_01625 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
MHPLLIDD_01626 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MHPLLIDD_01627 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHPLLIDD_01628 0.0 yxdM V ABC transporter (permease)
MHPLLIDD_01629 5.6e-141 yvcR V ABC transporter, ATP-binding protein
MHPLLIDD_01630 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MHPLLIDD_01631 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPLLIDD_01632 1.8e-33
MHPLLIDD_01633 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
MHPLLIDD_01634 1.6e-36 crh G Phosphocarrier protein Chr
MHPLLIDD_01635 1.4e-170 whiA K May be required for sporulation
MHPLLIDD_01636 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MHPLLIDD_01637 5.7e-166 rapZ S Displays ATPase and GTPase activities
MHPLLIDD_01638 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MHPLLIDD_01639 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHPLLIDD_01640 1.1e-97 usp CBM50 M protein conserved in bacteria
MHPLLIDD_01641 4.5e-277 S COG0457 FOG TPR repeat
MHPLLIDD_01642 0.0 msbA2 3.6.3.44 V ABC transporter
MHPLLIDD_01644 0.0
MHPLLIDD_01645 1.1e-73
MHPLLIDD_01646 7.6e-65
MHPLLIDD_01647 2.6e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MHPLLIDD_01648 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHPLLIDD_01649 5.8e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MHPLLIDD_01650 7.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHPLLIDD_01651 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MHPLLIDD_01652 5.8e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHPLLIDD_01653 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MHPLLIDD_01654 1.3e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MHPLLIDD_01655 3.8e-139 yvpB NU protein conserved in bacteria
MHPLLIDD_01656 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
MHPLLIDD_01657 7.3e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MHPLLIDD_01658 1.2e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MHPLLIDD_01659 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
MHPLLIDD_01660 9.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHPLLIDD_01661 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHPLLIDD_01662 2.5e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHPLLIDD_01663 5.6e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHPLLIDD_01664 8.1e-134 yvoA K transcriptional
MHPLLIDD_01665 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
MHPLLIDD_01666 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
MHPLLIDD_01667 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
MHPLLIDD_01668 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MHPLLIDD_01669 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
MHPLLIDD_01670 2.7e-203 yvmA EGP Major facilitator Superfamily
MHPLLIDD_01671 1.2e-50 yvlD S Membrane
MHPLLIDD_01672 2.6e-26 pspB KT PspC domain
MHPLLIDD_01673 3.4e-168 yvlB S Putative adhesin
MHPLLIDD_01674 8e-49 yvlA
MHPLLIDD_01675 6.7e-34 yvkN
MHPLLIDD_01676 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MHPLLIDD_01677 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHPLLIDD_01678 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHPLLIDD_01679 1.2e-30 csbA S protein conserved in bacteria
MHPLLIDD_01680 0.0 yvkC 2.7.9.2 GT Phosphotransferase
MHPLLIDD_01681 7e-101 yvkB K Transcriptional regulator
MHPLLIDD_01682 7.9e-228 yvkA EGP Major facilitator Superfamily
MHPLLIDD_01683 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHPLLIDD_01684 5.3e-56 swrA S Swarming motility protein
MHPLLIDD_01685 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MHPLLIDD_01686 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MHPLLIDD_01687 1.6e-123 ftsE D cell division ATP-binding protein FtsE
MHPLLIDD_01688 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
MHPLLIDD_01689 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MHPLLIDD_01690 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHPLLIDD_01691 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHPLLIDD_01692 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHPLLIDD_01693 5.4e-65
MHPLLIDD_01694 1.9e-08 fliT S bacterial-type flagellum organization
MHPLLIDD_01695 2.9e-69 fliS N flagellar protein FliS
MHPLLIDD_01696 1.1e-265 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MHPLLIDD_01697 6.1e-57 flaG N flagellar protein FlaG
MHPLLIDD_01698 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MHPLLIDD_01699 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MHPLLIDD_01700 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MHPLLIDD_01701 2.6e-50 yviE
MHPLLIDD_01702 1.1e-156 flgL N Belongs to the bacterial flagellin family
MHPLLIDD_01703 1.2e-264 flgK N flagellar hook-associated protein
MHPLLIDD_01704 2.4e-78 flgN NOU FlgN protein
MHPLLIDD_01705 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
MHPLLIDD_01706 7e-74 yvyF S flagellar protein
MHPLLIDD_01707 2.7e-129 comFC S Phosphoribosyl transferase domain
MHPLLIDD_01708 5.7e-46 comFB S Late competence development protein ComFB
MHPLLIDD_01709 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MHPLLIDD_01710 7.3e-155 degV S protein conserved in bacteria
MHPLLIDD_01711 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHPLLIDD_01712 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MHPLLIDD_01713 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MHPLLIDD_01714 6e-163 yvhJ K Transcriptional regulator
MHPLLIDD_01715 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MHPLLIDD_01716 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
MHPLLIDD_01717 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
MHPLLIDD_01718 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
MHPLLIDD_01719 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
MHPLLIDD_01720 4.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHPLLIDD_01721 7.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
MHPLLIDD_01722 5.3e-246 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHPLLIDD_01723 7.8e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MHPLLIDD_01724 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MHPLLIDD_01725 0.0 lytB 3.5.1.28 D Stage II sporulation protein
MHPLLIDD_01726 6e-38
MHPLLIDD_01727 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MHPLLIDD_01728 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MHPLLIDD_01729 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MHPLLIDD_01730 6.5e-57
MHPLLIDD_01731 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHPLLIDD_01732 7.5e-93 ggaA M Glycosyltransferase like family 2
MHPLLIDD_01733 3e-39 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHPLLIDD_01734 1.9e-54 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MHPLLIDD_01735 1.9e-36 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MHPLLIDD_01736 9.2e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MHPLLIDD_01737 4.1e-150 tagG GM Transport permease protein
MHPLLIDD_01738 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHPLLIDD_01739 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
MHPLLIDD_01740 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MHPLLIDD_01741 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MHPLLIDD_01742 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHPLLIDD_01743 3.5e-260
MHPLLIDD_01744 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHPLLIDD_01745 5.7e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
MHPLLIDD_01746 1.2e-261 gerBA EG Spore germination protein
MHPLLIDD_01747 1.5e-192 gerBB E Spore germination protein
MHPLLIDD_01748 3.2e-206 gerAC S Spore germination protein
MHPLLIDD_01749 1.9e-248 ywtG EGP Major facilitator Superfamily
MHPLLIDD_01750 8.4e-171 ywtF K Transcriptional regulator
MHPLLIDD_01751 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
MHPLLIDD_01752 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHPLLIDD_01753 3.6e-21 ywtC
MHPLLIDD_01754 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MHPLLIDD_01755 8.6e-70 pgsC S biosynthesis protein
MHPLLIDD_01756 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
MHPLLIDD_01757 9.3e-178 rbsR K transcriptional
MHPLLIDD_01758 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHPLLIDD_01759 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MHPLLIDD_01760 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MHPLLIDD_01761 2.1e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
MHPLLIDD_01762 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MHPLLIDD_01763 8.7e-93 batE T Sh3 type 3 domain protein
MHPLLIDD_01764 8e-48 ywsA S Protein of unknown function (DUF3892)
MHPLLIDD_01765 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
MHPLLIDD_01766 2.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MHPLLIDD_01767 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MHPLLIDD_01768 1.1e-169 alsR K LysR substrate binding domain
MHPLLIDD_01769 5.5e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHPLLIDD_01770 3.1e-124 ywrJ
MHPLLIDD_01771 8.2e-131 cotB
MHPLLIDD_01772 3.5e-210 cotH M Spore Coat
MHPLLIDD_01773 3.7e-12
MHPLLIDD_01774 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MHPLLIDD_01775 1.4e-53 S Domain of unknown function (DUF4181)
MHPLLIDD_01776 1.4e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MHPLLIDD_01777 8e-82 ywrC K Transcriptional regulator
MHPLLIDD_01778 1.2e-103 ywrB P Chromate transporter
MHPLLIDD_01779 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
MHPLLIDD_01781 1.1e-100 ywqN S NAD(P)H-dependent
MHPLLIDD_01782 1.4e-161 K Transcriptional regulator
MHPLLIDD_01783 3.2e-119 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MHPLLIDD_01784 3.9e-25
MHPLLIDD_01785 1.9e-82 ywqJ S Pre-toxin TG
MHPLLIDD_01786 5.2e-17
MHPLLIDD_01787 7.9e-43
MHPLLIDD_01788 9.7e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
MHPLLIDD_01789 8.6e-38 ywqI S Family of unknown function (DUF5344)
MHPLLIDD_01790 9.7e-23 S Domain of unknown function (DUF5082)
MHPLLIDD_01791 1.4e-152 ywqG S Domain of unknown function (DUF1963)
MHPLLIDD_01792 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHPLLIDD_01793 5.1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MHPLLIDD_01794 5.8e-118 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MHPLLIDD_01795 2e-116 ywqC M biosynthesis protein
MHPLLIDD_01796 1.2e-17
MHPLLIDD_01797 1.4e-308 ywqB S SWIM zinc finger
MHPLLIDD_01798 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHPLLIDD_01799 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
MHPLLIDD_01800 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
MHPLLIDD_01801 3.7e-57 ssbB L Single-stranded DNA-binding protein
MHPLLIDD_01802 3.8e-66 ywpG
MHPLLIDD_01803 1.1e-66 ywpF S YwpF-like protein
MHPLLIDD_01804 1.2e-49 srtA 3.4.22.70 M Sortase family
MHPLLIDD_01805 7e-153 ywpD T Histidine kinase
MHPLLIDD_01806 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHPLLIDD_01807 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHPLLIDD_01808 8.8e-198 S aspartate phosphatase
MHPLLIDD_01809 3.7e-140 flhP N flagellar basal body
MHPLLIDD_01810 9.9e-125 flhO N flagellar basal body
MHPLLIDD_01811 3.5e-180 mbl D Rod shape-determining protein
MHPLLIDD_01812 3e-44 spoIIID K Stage III sporulation protein D
MHPLLIDD_01813 2.1e-70 ywoH K COG1846 Transcriptional regulators
MHPLLIDD_01814 3.9e-210 ywoG EGP Major facilitator Superfamily
MHPLLIDD_01815 2.8e-231 ywoF P Right handed beta helix region
MHPLLIDD_01816 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
MHPLLIDD_01817 9.8e-242 ywoD EGP Major facilitator superfamily
MHPLLIDD_01818 4e-104 phzA Q Isochorismatase family
MHPLLIDD_01819 2.2e-76
MHPLLIDD_01820 2.5e-225 amt P Ammonium transporter
MHPLLIDD_01821 1.6e-58 nrgB K Belongs to the P(II) protein family
MHPLLIDD_01822 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MHPLLIDD_01823 3e-72 ywnJ S VanZ like family
MHPLLIDD_01824 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MHPLLIDD_01825 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MHPLLIDD_01826 8.9e-10 ywnC S Family of unknown function (DUF5362)
MHPLLIDD_01827 2.2e-70 ywnF S Family of unknown function (DUF5392)
MHPLLIDD_01828 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHPLLIDD_01829 5e-142 mta K transcriptional
MHPLLIDD_01830 2.6e-59 ywnC S Family of unknown function (DUF5362)
MHPLLIDD_01831 1.6e-114 ywnB S NAD(P)H-binding
MHPLLIDD_01832 1.7e-64 ywnA K Transcriptional regulator
MHPLLIDD_01833 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MHPLLIDD_01834 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MHPLLIDD_01835 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MHPLLIDD_01837 3.8e-11 csbD K CsbD-like
MHPLLIDD_01838 3e-84 ywmF S Peptidase M50
MHPLLIDD_01839 1.3e-103 S response regulator aspartate phosphatase
MHPLLIDD_01840 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MHPLLIDD_01841 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MHPLLIDD_01843 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
MHPLLIDD_01844 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
MHPLLIDD_01845 1e-174 spoIID D Stage II sporulation protein D
MHPLLIDD_01846 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHPLLIDD_01847 1.6e-134 ywmB S TATA-box binding
MHPLLIDD_01848 1.3e-32 ywzB S membrane
MHPLLIDD_01849 1.3e-60 ywmA
MHPLLIDD_01850 1.4e-13 ywmA
MHPLLIDD_01851 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MHPLLIDD_01852 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHPLLIDD_01853 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHPLLIDD_01854 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHPLLIDD_01855 1.6e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHPLLIDD_01856 3.9e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHPLLIDD_01857 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHPLLIDD_01858 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
MHPLLIDD_01859 2.5e-62 atpI S ATP synthase
MHPLLIDD_01860 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHPLLIDD_01861 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHPLLIDD_01862 3.6e-94 ywlG S Belongs to the UPF0340 family
MHPLLIDD_01863 8.3e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MHPLLIDD_01864 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHPLLIDD_01865 1.7e-91 mntP P Probably functions as a manganese efflux pump
MHPLLIDD_01866 5.2e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHPLLIDD_01867 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
MHPLLIDD_01868 6.1e-112 spoIIR S stage II sporulation protein R
MHPLLIDD_01869 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
MHPLLIDD_01871 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHPLLIDD_01872 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHPLLIDD_01873 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPLLIDD_01874 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MHPLLIDD_01875 8.6e-160 ywkB S Membrane transport protein
MHPLLIDD_01876 0.0 sfcA 1.1.1.38 C malic enzyme
MHPLLIDD_01877 1.6e-103 tdk 2.7.1.21 F thymidine kinase
MHPLLIDD_01878 1.1e-32 rpmE J Binds the 23S rRNA
MHPLLIDD_01879 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MHPLLIDD_01880 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MHPLLIDD_01881 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHPLLIDD_01882 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MHPLLIDD_01883 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MHPLLIDD_01884 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
MHPLLIDD_01885 5.1e-90 ywjG S Domain of unknown function (DUF2529)
MHPLLIDD_01886 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHPLLIDD_01887 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MHPLLIDD_01888 1.3e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MHPLLIDD_01889 0.0 fadF C COG0247 Fe-S oxidoreductase
MHPLLIDD_01890 1.5e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MHPLLIDD_01891 3.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MHPLLIDD_01892 2.7e-42 ywjC
MHPLLIDD_01893 4.8e-96 ywjB H RibD C-terminal domain
MHPLLIDD_01894 0.0 ywjA V ABC transporter
MHPLLIDD_01895 2.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHPLLIDD_01896 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
MHPLLIDD_01897 1.1e-93 narJ 1.7.5.1 C nitrate reductase
MHPLLIDD_01898 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
MHPLLIDD_01899 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHPLLIDD_01900 7e-86 arfM T cyclic nucleotide binding
MHPLLIDD_01901 1.7e-139 ywiC S YwiC-like protein
MHPLLIDD_01902 7.7e-129 fnr K helix_turn_helix, cAMP Regulatory protein
MHPLLIDD_01903 2.3e-213 narK P COG2223 Nitrate nitrite transporter
MHPLLIDD_01904 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MHPLLIDD_01905 4.7e-73 ywiB S protein conserved in bacteria
MHPLLIDD_01906 1e-07 S Bacteriocin subtilosin A
MHPLLIDD_01907 4.9e-270 C Fe-S oxidoreductases
MHPLLIDD_01909 3.3e-132 cbiO V ABC transporter
MHPLLIDD_01910 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MHPLLIDD_01911 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
MHPLLIDD_01912 1.6e-249 L Peptidase, M16
MHPLLIDD_01914 4.7e-244 ywhL CO amine dehydrogenase activity
MHPLLIDD_01915 3.2e-192 ywhK CO amine dehydrogenase activity
MHPLLIDD_01916 8.9e-79 S aspartate phosphatase
MHPLLIDD_01918 3.7e-28 ywhH S Aminoacyl-tRNA editing domain
MHPLLIDD_01919 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
MHPLLIDD_01920 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MHPLLIDD_01921 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MHPLLIDD_01922 3.6e-49
MHPLLIDD_01923 5.2e-95 ywhD S YwhD family
MHPLLIDD_01924 5.1e-119 ywhC S Peptidase family M50
MHPLLIDD_01925 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MHPLLIDD_01926 9.5e-71 ywhA K Transcriptional regulator
MHPLLIDD_01927 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHPLLIDD_01929 1.3e-236 mmr U Major Facilitator Superfamily
MHPLLIDD_01930 6.2e-79 yffB K Transcriptional regulator
MHPLLIDD_01931 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
MHPLLIDD_01932 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
MHPLLIDD_01933 3.1e-36 ywzC S Belongs to the UPF0741 family
MHPLLIDD_01934 1.6e-111 rsfA_1
MHPLLIDD_01935 2.2e-157 ywfM EG EamA-like transporter family
MHPLLIDD_01936 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MHPLLIDD_01937 1.1e-156 cysL K Transcriptional regulator
MHPLLIDD_01938 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MHPLLIDD_01939 1.1e-146 ywfI C May function as heme-dependent peroxidase
MHPLLIDD_01940 1.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
MHPLLIDD_01941 5e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
MHPLLIDD_01942 1.9e-209 bacE EGP Major facilitator Superfamily
MHPLLIDD_01943 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MHPLLIDD_01944 2.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPLLIDD_01945 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MHPLLIDD_01946 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MHPLLIDD_01947 6e-206 ywfA EGP Major facilitator Superfamily
MHPLLIDD_01948 4.8e-249 lysP E amino acid
MHPLLIDD_01949 0.0 rocB E arginine degradation protein
MHPLLIDD_01950 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHPLLIDD_01951 8.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MHPLLIDD_01952 3.4e-77
MHPLLIDD_01953 1.3e-86 spsL 5.1.3.13 M Spore Coat
MHPLLIDD_01954 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MHPLLIDD_01955 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MHPLLIDD_01956 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MHPLLIDD_01957 1.5e-183 spsG M Spore Coat
MHPLLIDD_01958 1e-128 spsF M Spore Coat
MHPLLIDD_01959 6e-213 spsE 2.5.1.56 M acid synthase
MHPLLIDD_01960 1.7e-162 spsD 2.3.1.210 K Spore Coat
MHPLLIDD_01961 1.1e-222 spsC E Belongs to the DegT DnrJ EryC1 family
MHPLLIDD_01962 1.4e-267 spsB M Capsule polysaccharide biosynthesis protein
MHPLLIDD_01963 4.5e-143 spsA M Spore Coat
MHPLLIDD_01964 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MHPLLIDD_01965 4.3e-59 ywdK S small membrane protein
MHPLLIDD_01966 3.7e-238 ywdJ F Xanthine uracil
MHPLLIDD_01967 6.6e-48 ywdI S Family of unknown function (DUF5327)
MHPLLIDD_01968 1e-259 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MHPLLIDD_01969 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHPLLIDD_01970 1.6e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
MHPLLIDD_01971 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MHPLLIDD_01972 2e-28 ywdA
MHPLLIDD_01973 1.4e-283 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
MHPLLIDD_01974 1.8e-251 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MHPLLIDD_01975 6.7e-139 focA P Formate/nitrite transporter
MHPLLIDD_01976 7e-150 sacT K transcriptional antiterminator
MHPLLIDD_01978 0.0 vpr O Belongs to the peptidase S8 family
MHPLLIDD_01979 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHPLLIDD_01980 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MHPLLIDD_01981 8.6e-202 rodA D Belongs to the SEDS family
MHPLLIDD_01982 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
MHPLLIDD_01983 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MHPLLIDD_01984 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MHPLLIDD_01985 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHPLLIDD_01986 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MHPLLIDD_01987 1e-35 ywzA S membrane
MHPLLIDD_01988 2.6e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MHPLLIDD_01989 1.9e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHPLLIDD_01990 9.5e-60 gtcA S GtrA-like protein
MHPLLIDD_01991 1.1e-121 ywcC K transcriptional regulator
MHPLLIDD_01993 9.8e-49 ywcB S Protein of unknown function, DUF485
MHPLLIDD_01994 6.9e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHPLLIDD_01995 4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MHPLLIDD_01996 3.2e-223 ywbN P Dyp-type peroxidase family protein
MHPLLIDD_01997 2e-163 ycdO P periplasmic lipoprotein involved in iron transport
MHPLLIDD_01998 9e-254 P COG0672 High-affinity Fe2 Pb2 permease
MHPLLIDD_01999 4.5e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MHPLLIDD_02000 1.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHPLLIDD_02001 4.3e-153 ywbI K Transcriptional regulator
MHPLLIDD_02002 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MHPLLIDD_02003 2.3e-111 ywbG M effector of murein hydrolase
MHPLLIDD_02004 8.1e-208 ywbF EGP Major facilitator Superfamily
MHPLLIDD_02005 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
MHPLLIDD_02006 3.5e-219 ywbD 2.1.1.191 J Methyltransferase
MHPLLIDD_02007 9.9e-67 ywbC 4.4.1.5 E glyoxalase
MHPLLIDD_02008 6.9e-96 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MHPLLIDD_02009 8.3e-125 ywbB S Protein of unknown function (DUF2711)
MHPLLIDD_02010 1.4e-240 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPLLIDD_02011 2.9e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
MHPLLIDD_02012 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MHPLLIDD_02013 7.6e-152 sacY K transcriptional antiterminator
MHPLLIDD_02014 4.5e-168 gspA M General stress
MHPLLIDD_02015 1.5e-124 ywaF S Integral membrane protein
MHPLLIDD_02016 1.2e-86 ywaE K Transcriptional regulator
MHPLLIDD_02017 3.9e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHPLLIDD_02018 3.7e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
MHPLLIDD_02019 4e-92 K Helix-turn-helix XRE-family like proteins
MHPLLIDD_02020 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
MHPLLIDD_02021 8.8e-130 ynfM EGP Major facilitator Superfamily
MHPLLIDD_02022 1.1e-115 ywaC 2.7.6.5 S protein conserved in bacteria
MHPLLIDD_02023 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MHPLLIDD_02024 5e-14 S D-Ala-teichoic acid biosynthesis protein
MHPLLIDD_02025 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPLLIDD_02026 3.6e-232 dltB M membrane protein involved in D-alanine export
MHPLLIDD_02027 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPLLIDD_02028 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MHPLLIDD_02029 8.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPLLIDD_02030 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MHPLLIDD_02031 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MHPLLIDD_02032 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MHPLLIDD_02033 7e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPLLIDD_02034 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
MHPLLIDD_02035 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
MHPLLIDD_02036 1.1e-19 yxzF
MHPLLIDD_02037 3.8e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MHPLLIDD_02038 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MHPLLIDD_02039 1.6e-211 yxlH EGP Major facilitator Superfamily
MHPLLIDD_02040 2.6e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHPLLIDD_02041 8.2e-165 yxlF V ABC transporter, ATP-binding protein
MHPLLIDD_02042 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
MHPLLIDD_02043 1.4e-30
MHPLLIDD_02044 1.6e-46 yxlC S Family of unknown function (DUF5345)
MHPLLIDD_02045 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
MHPLLIDD_02046 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
MHPLLIDD_02047 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHPLLIDD_02048 0.0 cydD V ATP-binding protein
MHPLLIDD_02049 4e-309 cydD V ATP-binding
MHPLLIDD_02050 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MHPLLIDD_02051 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
MHPLLIDD_02052 1.5e-229 cimH C COG3493 Na citrate symporter
MHPLLIDD_02053 9.4e-311 3.4.24.84 O Peptidase family M48
MHPLLIDD_02055 9.9e-152 yxkH G Polysaccharide deacetylase
MHPLLIDD_02056 5.9e-205 msmK P Belongs to the ABC transporter superfamily
MHPLLIDD_02057 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
MHPLLIDD_02058 2.5e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHPLLIDD_02059 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHPLLIDD_02060 2.8e-74 yxkC S Domain of unknown function (DUF4352)
MHPLLIDD_02061 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MHPLLIDD_02062 7.7e-77 S Protein of unknown function (DUF1453)
MHPLLIDD_02063 1.6e-190 yxjM T Signal transduction histidine kinase
MHPLLIDD_02064 9.8e-115 K helix_turn_helix, Lux Regulon
MHPLLIDD_02065 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MHPLLIDD_02067 1.4e-86 yxjI S LURP-one-related
MHPLLIDD_02068 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
MHPLLIDD_02069 1e-220 yxjG 2.1.1.14 E Methionine synthase
MHPLLIDD_02070 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MHPLLIDD_02071 3.4e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MHPLLIDD_02072 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MHPLLIDD_02073 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
MHPLLIDD_02074 5.5e-158 rlmA 2.1.1.187 Q Methyltransferase domain
MHPLLIDD_02075 5.4e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHPLLIDD_02076 1.5e-102 T Domain of unknown function (DUF4163)
MHPLLIDD_02077 3e-47 yxiS
MHPLLIDD_02078 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
MHPLLIDD_02079 6.6e-224 citH C Citrate transporter
MHPLLIDD_02080 3.6e-142 exoK GH16 M licheninase activity
MHPLLIDD_02081 8.3e-151 licT K transcriptional antiterminator
MHPLLIDD_02082 2e-110
MHPLLIDD_02083 5.6e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
MHPLLIDD_02084 5.6e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MHPLLIDD_02085 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
MHPLLIDD_02088 1.6e-48 yxiJ S YxiJ-like protein
MHPLLIDD_02089 1.2e-96 yxiI S Protein of unknown function (DUF2716)
MHPLLIDD_02090 3.8e-81
MHPLLIDD_02091 4.9e-46
MHPLLIDD_02092 3.7e-75 yxiG
MHPLLIDD_02093 6.4e-63
MHPLLIDD_02094 1.7e-84
MHPLLIDD_02095 1.5e-71 yxxG
MHPLLIDD_02096 0.0 wapA M COG3209 Rhs family protein
MHPLLIDD_02097 2.9e-168 yxxF EG EamA-like transporter family
MHPLLIDD_02098 1.1e-72 yxiE T Belongs to the universal stress protein A family
MHPLLIDD_02099 6.2e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHPLLIDD_02100 4.3e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MHPLLIDD_02101 3.6e-51
MHPLLIDD_02102 2.2e-78 S SMI1 / KNR4 family
MHPLLIDD_02103 0.0 S nuclease activity
MHPLLIDD_02104 3.6e-39 yxiC S Family of unknown function (DUF5344)
MHPLLIDD_02105 2.1e-21 S Domain of unknown function (DUF5082)
MHPLLIDD_02106 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MHPLLIDD_02107 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MHPLLIDD_02108 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
MHPLLIDD_02109 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MHPLLIDD_02110 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
MHPLLIDD_02111 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MHPLLIDD_02112 1.3e-249 lysP E amino acid
MHPLLIDD_02113 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MHPLLIDD_02114 8.3e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHPLLIDD_02115 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHPLLIDD_02116 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHPLLIDD_02117 1.3e-151 yxxB S Domain of Unknown Function (DUF1206)
MHPLLIDD_02118 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
MHPLLIDD_02119 2e-255 yxeQ S MmgE/PrpD family
MHPLLIDD_02120 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
MHPLLIDD_02121 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
MHPLLIDD_02122 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
MHPLLIDD_02123 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
MHPLLIDD_02124 7.5e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHPLLIDD_02125 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHPLLIDD_02127 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MHPLLIDD_02128 1.8e-150 yidA S hydrolases of the HAD superfamily
MHPLLIDD_02131 1.3e-20 yxeE
MHPLLIDD_02132 1.9e-16 yxeD
MHPLLIDD_02133 8.5e-69
MHPLLIDD_02134 5.1e-176 fhuD P ABC transporter
MHPLLIDD_02135 3.4e-58 yxeA S Protein of unknown function (DUF1093)
MHPLLIDD_02136 0.0 yxdM V ABC transporter (permease)
MHPLLIDD_02137 9.4e-141 yxdL V ABC transporter, ATP-binding protein
MHPLLIDD_02138 6.9e-181 T PhoQ Sensor
MHPLLIDD_02139 2.1e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPLLIDD_02140 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MHPLLIDD_02141 2.3e-137 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MHPLLIDD_02142 8.6e-167 iolH G Xylose isomerase-like TIM barrel
MHPLLIDD_02143 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MHPLLIDD_02144 5.1e-235 iolF EGP Major facilitator Superfamily
MHPLLIDD_02145 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MHPLLIDD_02146 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MHPLLIDD_02147 1.4e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MHPLLIDD_02148 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MHPLLIDD_02149 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHPLLIDD_02150 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
MHPLLIDD_02151 8.3e-176 iolS C Aldo keto reductase
MHPLLIDD_02153 8.3e-48 yxcD S Protein of unknown function (DUF2653)
MHPLLIDD_02154 2.3e-246 csbC EGP Major facilitator Superfamily
MHPLLIDD_02155 0.0 htpG O Molecular chaperone. Has ATPase activity
MHPLLIDD_02157 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
MHPLLIDD_02158 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
MHPLLIDD_02159 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MHPLLIDD_02160 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
MHPLLIDD_02161 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
MHPLLIDD_02162 3.3e-127 yxbB Q Met-10+ like-protein
MHPLLIDD_02163 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
MHPLLIDD_02164 1.1e-86 yxnB
MHPLLIDD_02165 0.0 asnB 6.3.5.4 E Asparagine synthase
MHPLLIDD_02166 7.6e-214 yxaM U MFS_1 like family
MHPLLIDD_02167 6.8e-93 S PQQ-like domain
MHPLLIDD_02168 3.5e-65 S Family of unknown function (DUF5391)
MHPLLIDD_02169 1.1e-75 yxaI S membrane protein domain
MHPLLIDD_02170 1.4e-228 P Protein of unknown function (DUF418)
MHPLLIDD_02171 1.3e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
MHPLLIDD_02172 1.2e-100 yxaF K Transcriptional regulator
MHPLLIDD_02173 1.9e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPLLIDD_02174 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
MHPLLIDD_02175 5.2e-50 S LrgA family
MHPLLIDD_02176 1.3e-117 yxaC M effector of murein hydrolase
MHPLLIDD_02177 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
MHPLLIDD_02178 1.9e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MHPLLIDD_02179 2.8e-126 gntR K transcriptional
MHPLLIDD_02180 2.8e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MHPLLIDD_02181 1e-230 gntP EG COG2610 H gluconate symporter and related permeases
MHPLLIDD_02182 1.8e-270 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHPLLIDD_02183 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MHPLLIDD_02184 1.9e-286 ahpF O Alkyl hydroperoxide reductase
MHPLLIDD_02185 5.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHPLLIDD_02186 3.4e-27 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MHPLLIDD_02187 1.9e-124 yydK K Transcriptional regulator
MHPLLIDD_02188 1.6e-118 S ABC-2 family transporter protein
MHPLLIDD_02189 1.6e-109 prrC P ABC transporter
MHPLLIDD_02190 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
MHPLLIDD_02191 1.3e-202 S SIR2-like domain
MHPLLIDD_02192 1.1e-180 L DNA synthesis involved in DNA repair
MHPLLIDD_02193 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHPLLIDD_02194 1.1e-09 S YyzF-like protein
MHPLLIDD_02195 1.3e-67
MHPLLIDD_02196 3.9e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHPLLIDD_02198 1.7e-30 yycQ S Protein of unknown function (DUF2651)
MHPLLIDD_02199 5.4e-201 yycP
MHPLLIDD_02200 8.4e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MHPLLIDD_02201 1.4e-83 yycN 2.3.1.128 K Acetyltransferase
MHPLLIDD_02202 1.1e-187 S aspartate phosphatase
MHPLLIDD_02204 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MHPLLIDD_02205 1.3e-260 rocE E amino acid
MHPLLIDD_02206 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MHPLLIDD_02207 7.4e-16
MHPLLIDD_02208 2.8e-94
MHPLLIDD_02209 2.3e-24 S Sporulation delaying protein SdpA
MHPLLIDD_02210 1.5e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MHPLLIDD_02211 1.5e-40 sdpR K transcriptional
MHPLLIDD_02212 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MHPLLIDD_02213 2.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
MHPLLIDD_02214 3.4e-94 K PFAM response regulator receiver
MHPLLIDD_02215 1.2e-73 S Peptidase propeptide and YPEB domain
MHPLLIDD_02216 3.8e-34 S Peptidase propeptide and YPEB domain
MHPLLIDD_02217 1.9e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHPLLIDD_02218 4.3e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MHPLLIDD_02219 7.3e-155 yycI S protein conserved in bacteria
MHPLLIDD_02220 4.9e-257 yycH S protein conserved in bacteria
MHPLLIDD_02221 0.0 vicK 2.7.13.3 T Histidine kinase
MHPLLIDD_02222 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPLLIDD_02227 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHPLLIDD_02228 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPLLIDD_02229 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MHPLLIDD_02230 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
MHPLLIDD_02232 1.9e-15 yycC K YycC-like protein
MHPLLIDD_02233 8.4e-221 yeaN P COG2807 Cyanate permease
MHPLLIDD_02234 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHPLLIDD_02235 2.2e-73 rplI J binds to the 23S rRNA
MHPLLIDD_02236 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MHPLLIDD_02237 8.3e-160 yybS S membrane
MHPLLIDD_02239 3.9e-84 cotF M Spore coat protein
MHPLLIDD_02240 1.7e-66 ydeP3 K Transcriptional regulator
MHPLLIDD_02241 5.6e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MHPLLIDD_02242 5.6e-61
MHPLLIDD_02244 3.9e-240 yybO G COG0477 Permeases of the major facilitator superfamily
MHPLLIDD_02245 4.3e-111 K TipAS antibiotic-recognition domain
MHPLLIDD_02246 4.8e-124
MHPLLIDD_02247 2.9e-66 yybH S SnoaL-like domain
MHPLLIDD_02248 3.5e-54 yybG S Pentapeptide repeat-containing protein
MHPLLIDD_02249 4.3e-217 ynfM EGP Major facilitator Superfamily
MHPLLIDD_02250 4e-164 yybE K Transcriptional regulator
MHPLLIDD_02251 1.1e-77 yjcF S Acetyltransferase (GNAT) domain
MHPLLIDD_02252 2.3e-73 yybC
MHPLLIDD_02253 1.4e-124 S Metallo-beta-lactamase superfamily
MHPLLIDD_02254 5.6e-77 yybA 2.3.1.57 K transcriptional
MHPLLIDD_02255 2.4e-72 yjcF S Acetyltransferase (GNAT) domain
MHPLLIDD_02256 5.5e-96 yyaS S Membrane
MHPLLIDD_02257 3e-90 yyaR K Acetyltransferase (GNAT) domain
MHPLLIDD_02258 1.3e-65 yyaQ S YjbR
MHPLLIDD_02259 2.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
MHPLLIDD_02260 1.2e-244 tetL EGP Major facilitator Superfamily
MHPLLIDD_02261 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
MHPLLIDD_02262 1.5e-60 yyaN K MerR HTH family regulatory protein
MHPLLIDD_02263 4.4e-161 yyaM EG EamA-like transporter family
MHPLLIDD_02264 3.9e-30 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MHPLLIDD_02265 5.7e-57 L Recombinase
MHPLLIDD_02267 2.3e-63 S Domain of unknown function with cystatin-like fold (DUF4467)
MHPLLIDD_02268 3.1e-84 yddI
MHPLLIDD_02269 3.8e-187 yddH CBM50 M Lysozyme-like
MHPLLIDD_02270 0.0 yddG S maturation of SSU-rRNA
MHPLLIDD_02271 1.4e-53 S Domain of unknown function (DUF1874)
MHPLLIDD_02272 0.0 yddE S AAA-like domain
MHPLLIDD_02273 1.9e-92 yddD S TcpE family
MHPLLIDD_02274 1.5e-39 yddC
MHPLLIDD_02275 1.2e-167 yddB S Conjugative transposon protein TcpC
MHPLLIDD_02277 4.3e-43 yddA
MHPLLIDD_02282 1e-182 nicK L Replication initiation factor
MHPLLIDD_02283 4.3e-272 ydcQ D Ftsk spoiiie family protein
MHPLLIDD_02284 5.1e-63 S Bacterial protein of unknown function (DUF961)
MHPLLIDD_02286 4.6e-14
MHPLLIDD_02287 1.7e-42 yvaO K Transcriptional
MHPLLIDD_02288 5.1e-45 immA E IrrE N-terminal-like domain
MHPLLIDD_02289 1.6e-67 S response regulator aspartate phosphatase
MHPLLIDD_02291 2.6e-21 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MHPLLIDD_02292 3.1e-101 S Type II restriction endonuclease EcoO109I
MHPLLIDD_02293 3.3e-218 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
MHPLLIDD_02294 1.3e-23 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MHPLLIDD_02295 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MHPLLIDD_02296 4e-167 yyaK S CAAX protease self-immunity
MHPLLIDD_02297 6.1e-244 EGP Major facilitator superfamily
MHPLLIDD_02298 8.1e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
MHPLLIDD_02299 1.3e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPLLIDD_02300 1.5e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
MHPLLIDD_02301 1.7e-142 xth 3.1.11.2 L exodeoxyribonuclease III
MHPLLIDD_02302 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHPLLIDD_02303 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHPLLIDD_02304 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
MHPLLIDD_02305 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHPLLIDD_02306 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHPLLIDD_02307 2.3e-33 yyzM S protein conserved in bacteria
MHPLLIDD_02308 8.1e-177 yyaD S Membrane
MHPLLIDD_02309 1.6e-111 yyaC S Sporulation protein YyaC
MHPLLIDD_02310 2.1e-149 spo0J K Belongs to the ParB family
MHPLLIDD_02311 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
MHPLLIDD_02312 9.6e-74 S Bacterial PH domain
MHPLLIDD_02313 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MHPLLIDD_02314 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MHPLLIDD_02315 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHPLLIDD_02316 8.9e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHPLLIDD_02317 6.5e-108 jag S single-stranded nucleic acid binding R3H
MHPLLIDD_02318 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHPLLIDD_02319 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MHPLLIDD_02320 7.8e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHPLLIDD_02321 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHPLLIDD_02322 2.4e-33 yaaA S S4 domain
MHPLLIDD_02323 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHPLLIDD_02324 1.8e-37 yaaB S Domain of unknown function (DUF370)
MHPLLIDD_02325 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHPLLIDD_02326 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHPLLIDD_02327 3.4e-39 S COG NOG14552 non supervised orthologous group
MHPLLIDD_02330 1e-181 yaaC S YaaC-like Protein
MHPLLIDD_02331 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MHPLLIDD_02332 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MHPLLIDD_02333 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MHPLLIDD_02334 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MHPLLIDD_02335 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHPLLIDD_02336 1.3e-09
MHPLLIDD_02337 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MHPLLIDD_02338 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MHPLLIDD_02339 5.6e-215 yaaH M Glycoside Hydrolase Family
MHPLLIDD_02340 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
MHPLLIDD_02341 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHPLLIDD_02342 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHPLLIDD_02343 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHPLLIDD_02344 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHPLLIDD_02345 7.9e-32 yaaL S Protein of unknown function (DUF2508)
MHPLLIDD_02346 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
MHPLLIDD_02347 3.4e-39 S COG NOG14552 non supervised orthologous group
MHPLLIDD_02350 1.7e-30 csfB S Inhibitor of sigma-G Gin
MHPLLIDD_02351 2.6e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MHPLLIDD_02352 1.2e-200 yaaN P Belongs to the TelA family
MHPLLIDD_02353 8.7e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MHPLLIDD_02354 2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHPLLIDD_02355 2.2e-54 yaaQ S protein conserved in bacteria
MHPLLIDD_02356 1.5e-71 yaaR S protein conserved in bacteria
MHPLLIDD_02357 1.1e-181 holB 2.7.7.7 L DNA polymerase III
MHPLLIDD_02358 6.1e-146 yaaT S stage 0 sporulation protein
MHPLLIDD_02359 4.8e-31 yabA L Involved in initiation control of chromosome replication
MHPLLIDD_02360 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
MHPLLIDD_02361 2.8e-48 yazA L endonuclease containing a URI domain
MHPLLIDD_02362 1e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHPLLIDD_02363 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
MHPLLIDD_02364 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHPLLIDD_02365 1.2e-143 tatD L hydrolase, TatD
MHPLLIDD_02366 2e-167 rpfB GH23 T protein conserved in bacteria
MHPLLIDD_02367 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHPLLIDD_02368 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHPLLIDD_02369 1.6e-136 yabG S peptidase
MHPLLIDD_02370 7.8e-39 veg S protein conserved in bacteria
MHPLLIDD_02371 8.3e-27 sspF S DNA topological change
MHPLLIDD_02372 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHPLLIDD_02373 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MHPLLIDD_02374 5.6e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MHPLLIDD_02375 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MHPLLIDD_02376 2.5e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHPLLIDD_02377 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHPLLIDD_02378 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MHPLLIDD_02379 2.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHPLLIDD_02380 2.4e-39 yabK S Peptide ABC transporter permease
MHPLLIDD_02381 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHPLLIDD_02382 1.5e-92 spoVT K stage V sporulation protein
MHPLLIDD_02383 2.1e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHPLLIDD_02384 3e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MHPLLIDD_02385 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MHPLLIDD_02386 1.5e-49 yabP S Sporulation protein YabP
MHPLLIDD_02387 2.5e-107 yabQ S spore cortex biosynthesis protein
MHPLLIDD_02388 1.1e-44 divIC D Septum formation initiator
MHPLLIDD_02389 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MHPLLIDD_02392 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MHPLLIDD_02393 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
MHPLLIDD_02394 1.4e-184 KLT serine threonine protein kinase
MHPLLIDD_02395 4.7e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHPLLIDD_02396 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MHPLLIDD_02397 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHPLLIDD_02398 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MHPLLIDD_02399 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHPLLIDD_02400 2.6e-158 yacD 5.2.1.8 O peptidyl-prolyl isomerase
MHPLLIDD_02401 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MHPLLIDD_02402 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHPLLIDD_02403 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MHPLLIDD_02404 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
MHPLLIDD_02405 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MHPLLIDD_02406 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHPLLIDD_02407 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MHPLLIDD_02408 4.1e-30 yazB K transcriptional
MHPLLIDD_02409 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHPLLIDD_02410 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MHPLLIDD_02411 3.4e-39 S COG NOG14552 non supervised orthologous group
MHPLLIDD_02416 2e-08
MHPLLIDD_02421 3.4e-39 S COG NOG14552 non supervised orthologous group
MHPLLIDD_02422 2.9e-76 ctsR K Belongs to the CtsR family
MHPLLIDD_02423 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MHPLLIDD_02424 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MHPLLIDD_02425 0.0 clpC O Belongs to the ClpA ClpB family
MHPLLIDD_02426 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHPLLIDD_02427 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MHPLLIDD_02428 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MHPLLIDD_02429 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MHPLLIDD_02430 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MHPLLIDD_02431 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHPLLIDD_02432 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
MHPLLIDD_02433 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHPLLIDD_02434 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHPLLIDD_02435 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHPLLIDD_02436 1.2e-88 yacP S RNA-binding protein containing a PIN domain
MHPLLIDD_02437 4.4e-115 sigH K Belongs to the sigma-70 factor family
MHPLLIDD_02438 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHPLLIDD_02439 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
MHPLLIDD_02440 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHPLLIDD_02441 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHPLLIDD_02442 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHPLLIDD_02443 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHPLLIDD_02444 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
MHPLLIDD_02445 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHPLLIDD_02446 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHPLLIDD_02447 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
MHPLLIDD_02448 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHPLLIDD_02449 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHPLLIDD_02450 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHPLLIDD_02451 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHPLLIDD_02452 2.2e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
MHPLLIDD_02453 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MHPLLIDD_02454 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHPLLIDD_02455 3e-105 rplD J Forms part of the polypeptide exit tunnel
MHPLLIDD_02456 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHPLLIDD_02457 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHPLLIDD_02458 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHPLLIDD_02459 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHPLLIDD_02460 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHPLLIDD_02461 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHPLLIDD_02462 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MHPLLIDD_02463 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHPLLIDD_02464 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHPLLIDD_02465 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHPLLIDD_02466 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHPLLIDD_02467 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHPLLIDD_02468 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHPLLIDD_02469 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHPLLIDD_02470 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHPLLIDD_02471 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHPLLIDD_02472 1.9e-23 rpmD J Ribosomal protein L30
MHPLLIDD_02473 1.8e-72 rplO J binds to the 23S rRNA
MHPLLIDD_02474 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHPLLIDD_02475 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHPLLIDD_02476 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
MHPLLIDD_02477 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHPLLIDD_02478 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MHPLLIDD_02479 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHPLLIDD_02480 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHPLLIDD_02481 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHPLLIDD_02482 3.6e-58 rplQ J Ribosomal protein L17
MHPLLIDD_02483 2.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHPLLIDD_02484 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHPLLIDD_02485 4e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHPLLIDD_02486 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHPLLIDD_02487 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHPLLIDD_02488 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MHPLLIDD_02489 3.4e-143 ybaJ Q Methyltransferase domain
MHPLLIDD_02490 9.7e-66 ybaK S Protein of unknown function (DUF2521)
MHPLLIDD_02491 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MHPLLIDD_02492 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MHPLLIDD_02493 1.2e-84 gerD
MHPLLIDD_02494 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MHPLLIDD_02495 7.9e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
MHPLLIDD_02496 3.4e-39 S COG NOG14552 non supervised orthologous group
MHPLLIDD_02499 2e-08
MHPLLIDD_02503 3.4e-39 S COG NOG14552 non supervised orthologous group
MHPLLIDD_02504 3.4e-39 S COG NOG14552 non supervised orthologous group
MHPLLIDD_02505 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
MHPLLIDD_02507 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
MHPLLIDD_02508 2.2e-142 ybbA S Putative esterase
MHPLLIDD_02509 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPLLIDD_02510 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPLLIDD_02511 1.4e-165 feuA P Iron-uptake system-binding protein
MHPLLIDD_02512 5e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
MHPLLIDD_02513 4.1e-239 ybbC 3.2.1.52 S protein conserved in bacteria
MHPLLIDD_02514 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MHPLLIDD_02515 4.2e-225 yfeW 3.4.16.4 V Belongs to the UPF0214 family
MHPLLIDD_02516 1.4e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MHPLLIDD_02517 2.1e-149 ybbH K transcriptional
MHPLLIDD_02518 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHPLLIDD_02519 1.9e-86 ybbJ J acetyltransferase
MHPLLIDD_02520 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
MHPLLIDD_02526 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MHPLLIDD_02527 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MHPLLIDD_02528 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHPLLIDD_02529 1.5e-224 ybbR S protein conserved in bacteria
MHPLLIDD_02530 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHPLLIDD_02531 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHPLLIDD_02532 1.5e-174 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MHPLLIDD_02533 5.8e-120 adaA 3.2.2.21 K Transcriptional regulator
MHPLLIDD_02534 1.2e-97 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHPLLIDD_02535 1.8e-276 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MHPLLIDD_02536 0.0 ybcC S Belongs to the UPF0753 family
MHPLLIDD_02537 4.7e-91 can 4.2.1.1 P carbonic anhydrase
MHPLLIDD_02539 5.6e-46
MHPLLIDD_02540 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
MHPLLIDD_02541 5.1e-50 ybzH K Helix-turn-helix domain
MHPLLIDD_02542 4.2e-201 ybcL EGP Major facilitator Superfamily
MHPLLIDD_02544 9.1e-239 J 4Fe-4S single cluster domain
MHPLLIDD_02545 1.6e-277 V CAAX protease self-immunity
MHPLLIDD_02546 1.9e-135 skfE V ABC transporter
MHPLLIDD_02547 4e-248 skfF S ABC transporter
MHPLLIDD_02548 7.8e-91 C HEAT repeats
MHPLLIDD_02549 1.1e-77 txn CO Thioredoxin-like
MHPLLIDD_02550 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MHPLLIDD_02551 3.8e-122 T Transcriptional regulatory protein, C terminal
MHPLLIDD_02552 1.8e-168 T His Kinase A (phospho-acceptor) domain
MHPLLIDD_02554 3.9e-139 KLT Protein tyrosine kinase
MHPLLIDD_02555 8.5e-151 ybdN
MHPLLIDD_02556 1.5e-214 ybdO S Domain of unknown function (DUF4885)
MHPLLIDD_02557 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MHPLLIDD_02558 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
MHPLLIDD_02559 4.9e-30 ybxH S Family of unknown function (DUF5370)
MHPLLIDD_02560 1.8e-150 ybxI 3.5.2.6 V beta-lactamase
MHPLLIDD_02561 7.6e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MHPLLIDD_02562 4.9e-41 ybyB
MHPLLIDD_02563 8.8e-290 ybeC E amino acid
MHPLLIDD_02564 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MHPLLIDD_02565 7.3e-258 glpT G -transporter
MHPLLIDD_02566 2.9e-35 S Protein of unknown function (DUF2651)
MHPLLIDD_02567 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
MHPLLIDD_02568 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
MHPLLIDD_02571 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
MHPLLIDD_02572 3.7e-160 ybfH EG EamA-like transporter family
MHPLLIDD_02573 5.2e-145 msmR K AraC-like ligand binding domain
MHPLLIDD_02574 2.2e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MHPLLIDD_02575 2.9e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
MHPLLIDD_02577 1e-167 S Alpha/beta hydrolase family
MHPLLIDD_02578 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHPLLIDD_02579 2.7e-85 ybfM S SNARE associated Golgi protein
MHPLLIDD_02580 6.9e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MHPLLIDD_02581 2e-45 ybfN
MHPLLIDD_02582 3.3e-191 yceA S Belongs to the UPF0176 family
MHPLLIDD_02583 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHPLLIDD_02584 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MHPLLIDD_02585 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHPLLIDD_02586 4.9e-128 K UTRA
MHPLLIDD_02588 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MHPLLIDD_02589 1.4e-259 mmuP E amino acid
MHPLLIDD_02590 1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
MHPLLIDD_02591 2.8e-255 agcS E Sodium alanine symporter
MHPLLIDD_02592 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
MHPLLIDD_02593 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
MHPLLIDD_02594 2.6e-169 glnL T Regulator
MHPLLIDD_02595 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
MHPLLIDD_02596 3.2e-270 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHPLLIDD_02597 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
MHPLLIDD_02598 1.2e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MHPLLIDD_02599 2.1e-123 ycbG K FCD
MHPLLIDD_02600 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
MHPLLIDD_02601 8.6e-167 ycbJ S Macrolide 2'-phosphotransferase
MHPLLIDD_02602 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
MHPLLIDD_02603 5.4e-167 eamA1 EG spore germination
MHPLLIDD_02604 8.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPLLIDD_02605 4.2e-167 T PhoQ Sensor
MHPLLIDD_02606 3.5e-166 ycbN V ABC transporter, ATP-binding protein
MHPLLIDD_02607 1.8e-114 S ABC-2 family transporter protein
MHPLLIDD_02608 8.2e-53 ycbP S Protein of unknown function (DUF2512)
MHPLLIDD_02609 2.8e-78 sleB 3.5.1.28 M Cell wall
MHPLLIDD_02610 3.6e-134 ycbR T vWA found in TerF C terminus
MHPLLIDD_02611 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
MHPLLIDD_02612 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MHPLLIDD_02613 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MHPLLIDD_02614 6.9e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MHPLLIDD_02615 2.9e-199 ycbU E Selenocysteine lyase
MHPLLIDD_02616 3e-225 lmrB EGP the major facilitator superfamily
MHPLLIDD_02617 4.8e-102 yxaF K Transcriptional regulator
MHPLLIDD_02618 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MHPLLIDD_02619 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MHPLLIDD_02620 4.9e-58 S RDD family
MHPLLIDD_02621 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
MHPLLIDD_02622 1.2e-156 2.7.13.3 T GHKL domain
MHPLLIDD_02623 1.2e-126 lytR_2 T LytTr DNA-binding domain
MHPLLIDD_02624 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
MHPLLIDD_02625 2.7e-200 natB CP ABC-2 family transporter protein
MHPLLIDD_02626 1.7e-22 yccK C Aldo keto reductase
MHPLLIDD_02627 1e-142 yccK C Aldo keto reductase
MHPLLIDD_02628 6.6e-177 ycdA S Domain of unknown function (DUF5105)
MHPLLIDD_02629 4.2e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
MHPLLIDD_02630 1.5e-259 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
MHPLLIDD_02631 2.1e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
MHPLLIDD_02632 6.1e-173 S response regulator aspartate phosphatase
MHPLLIDD_02633 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
MHPLLIDD_02634 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
MHPLLIDD_02635 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
MHPLLIDD_02636 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MHPLLIDD_02637 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MHPLLIDD_02638 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHPLLIDD_02639 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
MHPLLIDD_02640 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
MHPLLIDD_02641 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
MHPLLIDD_02642 6.3e-137 terC P Protein of unknown function (DUF475)
MHPLLIDD_02643 0.0 yceG S Putative component of 'biosynthetic module'
MHPLLIDD_02644 2e-192 yceH P Belongs to the TelA family
MHPLLIDD_02645 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
MHPLLIDD_02646 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
MHPLLIDD_02647 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
MHPLLIDD_02648 5.1e-229 proV 3.6.3.32 E glycine betaine
MHPLLIDD_02649 1.3e-127 opuAB P glycine betaine
MHPLLIDD_02650 1.5e-163 opuAC E glycine betaine
MHPLLIDD_02651 1.1e-217 amhX S amidohydrolase
MHPLLIDD_02652 1.9e-256 ycgA S Membrane
MHPLLIDD_02653 4.1e-81 ycgB
MHPLLIDD_02654 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
MHPLLIDD_02655 1.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MHPLLIDD_02656 3.3e-289 lctP C L-lactate permease
MHPLLIDD_02657 1.8e-260 mdr EGP Major facilitator Superfamily
MHPLLIDD_02658 2.9e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
MHPLLIDD_02659 2e-112 ycgF E Lysine exporter protein LysE YggA
MHPLLIDD_02660 7.6e-151 yqcI S YqcI/YcgG family
MHPLLIDD_02661 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MHPLLIDD_02662 2.4e-112 ycgI S Domain of unknown function (DUF1989)
MHPLLIDD_02663 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHPLLIDD_02664 2.1e-108 tmrB S AAA domain
MHPLLIDD_02666 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MHPLLIDD_02667 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
MHPLLIDD_02668 5.1e-176 oxyR3 K LysR substrate binding domain
MHPLLIDD_02669 3.6e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MHPLLIDD_02670 2.9e-145 ycgL S Predicted nucleotidyltransferase
MHPLLIDD_02671 5.1e-170 ycgM E Proline dehydrogenase
MHPLLIDD_02672 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHPLLIDD_02673 2e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHPLLIDD_02674 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
MHPLLIDD_02675 9.1e-145 ycgQ S membrane
MHPLLIDD_02676 9.1e-140 ycgR S permeases
MHPLLIDD_02677 1.6e-157 I alpha/beta hydrolase fold
MHPLLIDD_02678 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MHPLLIDD_02679 3e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MHPLLIDD_02680 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
MHPLLIDD_02681 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MHPLLIDD_02682 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHPLLIDD_02683 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
MHPLLIDD_02684 1.4e-220 nasA P COG2223 Nitrate nitrite transporter
MHPLLIDD_02685 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
MHPLLIDD_02686 5.5e-109 yciB M ErfK YbiS YcfS YnhG
MHPLLIDD_02687 4.6e-227 yciC S GTPases (G3E family)
MHPLLIDD_02688 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
MHPLLIDD_02689 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MHPLLIDD_02692 6.2e-76 yckC S membrane
MHPLLIDD_02693 7.8e-52 yckD S Protein of unknown function (DUF2680)
MHPLLIDD_02694 8e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHPLLIDD_02695 6.5e-69 nin S Competence protein J (ComJ)
MHPLLIDD_02696 3e-70 nucA M Deoxyribonuclease NucA/NucB
MHPLLIDD_02697 1.9e-186 tlpC 2.7.13.3 NT chemotaxis protein
MHPLLIDD_02698 3e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
MHPLLIDD_02699 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MHPLLIDD_02700 1.3e-63 hxlR K transcriptional
MHPLLIDD_02701 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPLLIDD_02702 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPLLIDD_02703 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
MHPLLIDD_02704 6.4e-139 srfAD Q thioesterase
MHPLLIDD_02705 6.1e-227 EGP Major Facilitator Superfamily
MHPLLIDD_02706 2.3e-88 S YcxB-like protein
MHPLLIDD_02707 6.4e-160 ycxC EG EamA-like transporter family
MHPLLIDD_02708 5.6e-250 ycxD K GntR family transcriptional regulator
MHPLLIDD_02709 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MHPLLIDD_02710 1.7e-114 yczE S membrane
MHPLLIDD_02711 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MHPLLIDD_02712 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
MHPLLIDD_02713 1.3e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MHPLLIDD_02714 4.9e-162 bsdA K LysR substrate binding domain
MHPLLIDD_02715 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MHPLLIDD_02716 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MHPLLIDD_02717 4e-39 bsdD 4.1.1.61 S response to toxic substance
MHPLLIDD_02718 2.3e-81 yclD
MHPLLIDD_02719 1.9e-158 yclE 3.4.11.5 S Alpha beta hydrolase
MHPLLIDD_02720 7.3e-267 dtpT E amino acid peptide transporter
MHPLLIDD_02721 5.9e-292 yclG M Pectate lyase superfamily protein
MHPLLIDD_02723 1.9e-276 gerKA EG Spore germination protein
MHPLLIDD_02724 8e-227 gerKC S spore germination
MHPLLIDD_02725 1e-196 gerKB F Spore germination protein
MHPLLIDD_02726 5.6e-121 yclH P ABC transporter
MHPLLIDD_02727 1.1e-195 yclI V ABC transporter (permease) YclI
MHPLLIDD_02728 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPLLIDD_02729 5.2e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MHPLLIDD_02730 2e-70 S aspartate phosphatase
MHPLLIDD_02733 5.7e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
MHPLLIDD_02734 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPLLIDD_02735 1.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPLLIDD_02736 1.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MHPLLIDD_02737 1.4e-170 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MHPLLIDD_02738 1.4e-251 ycnB EGP Major facilitator Superfamily
MHPLLIDD_02739 7.9e-152 ycnC K Transcriptional regulator
MHPLLIDD_02740 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
MHPLLIDD_02741 1.6e-45 ycnE S Monooxygenase
MHPLLIDD_02742 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
MHPLLIDD_02743 5.6e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHPLLIDD_02744 2e-244 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHPLLIDD_02745 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHPLLIDD_02746 1.8e-148 glcU U Glucose uptake
MHPLLIDD_02747 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPLLIDD_02748 2.9e-100 ycnI S protein conserved in bacteria
MHPLLIDD_02749 4.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
MHPLLIDD_02750 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
MHPLLIDD_02751 1.6e-55
MHPLLIDD_02752 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MHPLLIDD_02753 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MHPLLIDD_02754 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MHPLLIDD_02755 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MHPLLIDD_02756 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MHPLLIDD_02757 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MHPLLIDD_02758 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
MHPLLIDD_02759 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MHPLLIDD_02761 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MHPLLIDD_02762 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
MHPLLIDD_02763 5.1e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MHPLLIDD_02764 8.1e-148 ycsI S Belongs to the D-glutamate cyclase family
MHPLLIDD_02765 1.2e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MHPLLIDD_02766 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MHPLLIDD_02767 1.2e-132 kipR K Transcriptional regulator
MHPLLIDD_02768 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
MHPLLIDD_02770 1.4e-49 yczJ S biosynthesis
MHPLLIDD_02771 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MHPLLIDD_02772 2.4e-172 ydhF S Oxidoreductase
MHPLLIDD_02773 0.0 mtlR K transcriptional regulator, MtlR
MHPLLIDD_02774 2.1e-293 ydaB IQ acyl-CoA ligase
MHPLLIDD_02775 9e-99 ydaC Q Methyltransferase domain
MHPLLIDD_02776 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPLLIDD_02777 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
MHPLLIDD_02778 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHPLLIDD_02779 6.8e-77 ydaG 1.4.3.5 S general stress protein
MHPLLIDD_02780 1e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MHPLLIDD_02781 3.3e-46 ydzA EGP Major facilitator Superfamily
MHPLLIDD_02782 2.5e-74 lrpC K Transcriptional regulator
MHPLLIDD_02783 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHPLLIDD_02784 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
MHPLLIDD_02785 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
MHPLLIDD_02786 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MHPLLIDD_02787 4.5e-233 ydaM M Glycosyl transferase family group 2
MHPLLIDD_02788 0.0 ydaN S Bacterial cellulose synthase subunit
MHPLLIDD_02789 0.0 ydaO E amino acid
MHPLLIDD_02790 1.9e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MHPLLIDD_02791 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MHPLLIDD_02792 2.1e-39
MHPLLIDD_02793 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
MHPLLIDD_02795 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
MHPLLIDD_02796 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
MHPLLIDD_02798 8.9e-59 ydbB G Cupin domain
MHPLLIDD_02799 3.1e-62 ydbC S Domain of unknown function (DUF4937
MHPLLIDD_02800 3.5e-154 ydbD P Catalase
MHPLLIDD_02801 5.1e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MHPLLIDD_02802 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MHPLLIDD_02803 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
MHPLLIDD_02804 5.3e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHPLLIDD_02805 9.7e-181 ydbI S AI-2E family transporter
MHPLLIDD_02806 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
MHPLLIDD_02807 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHPLLIDD_02808 2.7e-52 ydbL
MHPLLIDD_02809 1.4e-217 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MHPLLIDD_02810 1.1e-18 S Fur-regulated basic protein B
MHPLLIDD_02811 2.2e-07 S Fur-regulated basic protein A
MHPLLIDD_02812 9.6e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHPLLIDD_02813 4.3e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MHPLLIDD_02814 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MHPLLIDD_02815 6.9e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHPLLIDD_02816 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHPLLIDD_02817 2.1e-82 ydbS S Bacterial PH domain
MHPLLIDD_02818 1.1e-259 ydbT S Membrane
MHPLLIDD_02819 2.2e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MHPLLIDD_02820 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHPLLIDD_02821 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MHPLLIDD_02822 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHPLLIDD_02823 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MHPLLIDD_02824 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MHPLLIDD_02825 2.8e-143 rsbR T Positive regulator of sigma-B
MHPLLIDD_02826 5.2e-57 rsbS T antagonist
MHPLLIDD_02827 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MHPLLIDD_02828 7.1e-189 rsbU 3.1.3.3 KT phosphatase
MHPLLIDD_02829 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
MHPLLIDD_02830 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MHPLLIDD_02831 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPLLIDD_02832 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MHPLLIDD_02836 1.5e-82 ydcG S EVE domain
MHPLLIDD_02837 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
MHPLLIDD_02838 0.0 yhgF K COG2183 Transcriptional accessory protein
MHPLLIDD_02839 1.6e-84 ydcK S Belongs to the SprT family
MHPLLIDD_02847 1.7e-75 rimJ2 J Acetyltransferase (GNAT) domain
MHPLLIDD_02848 8.5e-45
MHPLLIDD_02849 5.7e-138 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MHPLLIDD_02850 1.7e-32 K Helix-turn-helix XRE-family like proteins
MHPLLIDD_02851 9.6e-40
MHPLLIDD_02855 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MHPLLIDD_02856 8.7e-30 cspL K Cold shock
MHPLLIDD_02857 1.5e-77 carD K Transcription factor
MHPLLIDD_02858 4.4e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHPLLIDD_02859 1.4e-164 rhaS5 K AraC-like ligand binding domain
MHPLLIDD_02860 3.2e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHPLLIDD_02861 1.4e-164 ydeE K AraC family transcriptional regulator
MHPLLIDD_02862 1.1e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHPLLIDD_02863 1.8e-216 ydeG EGP Major facilitator superfamily
MHPLLIDD_02864 2.7e-45 ydeH
MHPLLIDD_02865 2.4e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
MHPLLIDD_02866 1.3e-109
MHPLLIDD_02867 1.1e-31 S SNARE associated Golgi protein
MHPLLIDD_02868 1.8e-14 ptsH G PTS HPr component phosphorylation site
MHPLLIDD_02869 3.4e-84 K Transcriptional regulator C-terminal region
MHPLLIDD_02870 2e-152 ydeK EG -transporter
MHPLLIDD_02871 8.7e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHPLLIDD_02872 1.3e-72 maoC I N-terminal half of MaoC dehydratase
MHPLLIDD_02873 1.8e-104 ydeN S Serine hydrolase
MHPLLIDD_02874 5.7e-55 K HxlR-like helix-turn-helix
MHPLLIDD_02875 6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MHPLLIDD_02876 1.8e-68 ydeP K Transcriptional regulator
MHPLLIDD_02877 1.7e-110 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
MHPLLIDD_02878 1.5e-185 ydeR EGP Major facilitator Superfamily
MHPLLIDD_02879 2.5e-104 ydeS K Transcriptional regulator
MHPLLIDD_02880 1.8e-56 arsR K transcriptional
MHPLLIDD_02881 2.6e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHPLLIDD_02882 7.2e-149 ydfB J GNAT acetyltransferase
MHPLLIDD_02883 1e-162 ydfC EG EamA-like transporter family
MHPLLIDD_02884 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHPLLIDD_02885 3.8e-116 ydfE S Flavin reductase like domain
MHPLLIDD_02886 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
MHPLLIDD_02887 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MHPLLIDD_02889 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
MHPLLIDD_02890 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHPLLIDD_02891 0.0 ydfJ S drug exporters of the RND superfamily
MHPLLIDD_02892 1.9e-177 S Alpha/beta hydrolase family
MHPLLIDD_02893 5.9e-118 S Protein of unknown function (DUF554)
MHPLLIDD_02894 3.2e-147 K Bacterial transcription activator, effector binding domain
MHPLLIDD_02895 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHPLLIDD_02896 9.6e-112 ydfN C nitroreductase
MHPLLIDD_02897 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
MHPLLIDD_02898 8.8e-63 mhqP S DoxX
MHPLLIDD_02899 1.3e-57 traF CO Thioredoxin
MHPLLIDD_02900 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
MHPLLIDD_02901 6.3e-29
MHPLLIDD_02903 4.4e-118 ydfR S Protein of unknown function (DUF421)
MHPLLIDD_02904 5.2e-122 ydfS S Protein of unknown function (DUF421)
MHPLLIDD_02905 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
MHPLLIDD_02906 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
MHPLLIDD_02907 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
MHPLLIDD_02908 3e-94 K Bacterial regulatory proteins, tetR family
MHPLLIDD_02909 1.6e-52 S DoxX-like family
MHPLLIDD_02910 6.9e-86 yycN 2.3.1.128 K Acetyltransferase
MHPLLIDD_02911 5.1e-134 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MHPLLIDD_02912 2e-119 purR K helix_turn _helix lactose operon repressor
MHPLLIDD_02913 1e-190 csbC EGP Major facilitator Superfamily
MHPLLIDD_02914 4.4e-104 G Xylose isomerase-like TIM barrel
MHPLLIDD_02915 1.7e-301 expZ S ABC transporter
MHPLLIDD_02916 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MHPLLIDD_02917 2.3e-90 dinB S DinB family
MHPLLIDD_02918 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
MHPLLIDD_02919 0.0 ydgH S drug exporters of the RND superfamily
MHPLLIDD_02920 8.8e-113 drgA C nitroreductase
MHPLLIDD_02921 2.4e-69 ydgJ K Winged helix DNA-binding domain
MHPLLIDD_02922 4.8e-208 tcaB EGP Major facilitator Superfamily
MHPLLIDD_02923 1.6e-121 ydhB S membrane transporter protein
MHPLLIDD_02924 6.5e-122 ydhC K FCD
MHPLLIDD_02925 6.3e-243 ydhD M Glycosyl hydrolase
MHPLLIDD_02926 2.9e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MHPLLIDD_02927 4.2e-127
MHPLLIDD_02928 2.6e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MHPLLIDD_02929 8.7e-68 frataxin S Domain of unknown function (DU1801)
MHPLLIDD_02931 1.5e-80 K Acetyltransferase (GNAT) domain
MHPLLIDD_02932 1e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MHPLLIDD_02933 2.5e-98 ydhK M Protein of unknown function (DUF1541)
MHPLLIDD_02934 4.6e-200 pbuE EGP Major facilitator Superfamily
MHPLLIDD_02935 4.2e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MHPLLIDD_02936 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
MHPLLIDD_02937 9.8e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPLLIDD_02938 7.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHPLLIDD_02939 7.4e-132 ydhQ K UTRA
MHPLLIDD_02940 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MHPLLIDD_02941 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MHPLLIDD_02942 9e-214 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MHPLLIDD_02943 6.1e-157 ydhU P Catalase
MHPLLIDD_02946 3.4e-39 S COG NOG14552 non supervised orthologous group
MHPLLIDD_02947 7.8e-08
MHPLLIDD_02949 1.3e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MHPLLIDD_02950 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MHPLLIDD_02951 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MHPLLIDD_02952 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MHPLLIDD_02953 2e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHPLLIDD_02954 0.0 ydiF S ABC transporter
MHPLLIDD_02955 2.1e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MHPLLIDD_02956 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHPLLIDD_02957 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MHPLLIDD_02958 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MHPLLIDD_02959 2.9e-27 ydiK S Domain of unknown function (DUF4305)
MHPLLIDD_02960 7.9e-129 ydiL S CAAX protease self-immunity
MHPLLIDD_02961 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHPLLIDD_02962 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHPLLIDD_02964 6.4e-66 KL Phage plasmid primase P4 family
MHPLLIDD_02965 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
MHPLLIDD_02966 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MHPLLIDD_02968 1.2e-199 V AAA domain (dynein-related subfamily)
MHPLLIDD_02969 4.9e-257 J LlaJI restriction endonuclease
MHPLLIDD_02970 1.1e-08 ydjC S Abhydrolase domain containing 18
MHPLLIDD_02971 0.0 K NB-ARC domain
MHPLLIDD_02972 9.4e-200 gutB 1.1.1.14 E Dehydrogenase
MHPLLIDD_02973 7.1e-256 gutA G MFS/sugar transport protein
MHPLLIDD_02974 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
MHPLLIDD_02975 5.1e-114 pspA KT Phage shock protein A
MHPLLIDD_02976 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHPLLIDD_02977 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
MHPLLIDD_02978 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
MHPLLIDD_02979 4.7e-196 S Ion transport 2 domain protein
MHPLLIDD_02980 2.7e-258 iolT EGP Major facilitator Superfamily
MHPLLIDD_02981 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MHPLLIDD_02982 4.5e-64 ydjM M Lytic transglycolase
MHPLLIDD_02983 2.3e-150 ydjN U Involved in the tonB-independent uptake of proteins
MHPLLIDD_02985 1.4e-34 ydjO S Cold-inducible protein YdjO
MHPLLIDD_02986 8.4e-156 ydjP I Alpha/beta hydrolase family
MHPLLIDD_02987 3.3e-175 yeaA S Protein of unknown function (DUF4003)
MHPLLIDD_02988 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MHPLLIDD_02989 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
MHPLLIDD_02990 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHPLLIDD_02991 1.5e-175 yeaC S COG0714 MoxR-like ATPases
MHPLLIDD_02992 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MHPLLIDD_02993 0.0 yebA E COG1305 Transglutaminase-like enzymes
MHPLLIDD_02994 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MHPLLIDD_02995 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
MHPLLIDD_02996 9.8e-256 S Domain of unknown function (DUF4179)
MHPLLIDD_02997 7.8e-212 pbuG S permease
MHPLLIDD_02998 8.3e-116 yebC M Membrane
MHPLLIDD_03000 8.9e-93 yebE S UPF0316 protein
MHPLLIDD_03001 8e-28 yebG S NETI protein
MHPLLIDD_03002 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHPLLIDD_03003 4.5e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHPLLIDD_03004 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHPLLIDD_03005 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MHPLLIDD_03006 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHPLLIDD_03007 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHPLLIDD_03008 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHPLLIDD_03009 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHPLLIDD_03010 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MHPLLIDD_03011 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MHPLLIDD_03012 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MHPLLIDD_03013 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
MHPLLIDD_03014 3.5e-73 K helix_turn_helix ASNC type
MHPLLIDD_03015 6.4e-227 yjeH E Amino acid permease
MHPLLIDD_03016 2.7e-27 S Protein of unknown function (DUF2892)
MHPLLIDD_03017 0.0 yerA 3.5.4.2 F adenine deaminase
MHPLLIDD_03018 8.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
MHPLLIDD_03019 4.8e-51 yerC S protein conserved in bacteria
MHPLLIDD_03020 8.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
MHPLLIDD_03021 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MHPLLIDD_03022 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MHPLLIDD_03023 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHPLLIDD_03024 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
MHPLLIDD_03025 2.7e-196 yerI S homoserine kinase type II (protein kinase fold)
MHPLLIDD_03026 6.1e-123 sapB S MgtC SapB transporter
MHPLLIDD_03027 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHPLLIDD_03028 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHPLLIDD_03029 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHPLLIDD_03030 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHPLLIDD_03031 1.3e-148 yerO K Transcriptional regulator
MHPLLIDD_03032 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MHPLLIDD_03033 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MHPLLIDD_03034 1.6e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHPLLIDD_03035 0.0 L Type III restriction enzyme res subunit
MHPLLIDD_03037 4.4e-43
MHPLLIDD_03039 1.4e-100 S response regulator aspartate phosphatase
MHPLLIDD_03041 2.7e-27
MHPLLIDD_03042 4.2e-75 S Protein of unknown function, DUF600
MHPLLIDD_03043 0.0 L nucleic acid phosphodiester bond hydrolysis
MHPLLIDD_03045 8.7e-101 L endonuclease activity
MHPLLIDD_03046 2e-125 3.4.24.40 CO amine dehydrogenase activity
MHPLLIDD_03047 4.1e-26 3.4.24.40 CO amine dehydrogenase activity
MHPLLIDD_03048 1e-39
MHPLLIDD_03049 1.6e-213 S Tetratricopeptide repeat
MHPLLIDD_03051 2.7e-126 yeeN K transcriptional regulatory protein
MHPLLIDD_03053 8.5e-102 dhaR3 K Transcriptional regulator
MHPLLIDD_03054 2.5e-77 yesE S SnoaL-like domain
MHPLLIDD_03055 5.5e-142 yesF GM NAD(P)H-binding
MHPLLIDD_03056 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
MHPLLIDD_03057 1.5e-45 cotJB S CotJB protein
MHPLLIDD_03058 5.2e-104 cotJC P Spore Coat
MHPLLIDD_03059 1.3e-101 yesJ K Acetyltransferase (GNAT) family
MHPLLIDD_03060 1.2e-101 yesL S Protein of unknown function, DUF624
MHPLLIDD_03061 0.0 yesM 2.7.13.3 T Histidine kinase
MHPLLIDD_03062 1.4e-201 yesN K helix_turn_helix, arabinose operon control protein
MHPLLIDD_03063 1.6e-246 yesO G Bacterial extracellular solute-binding protein
MHPLLIDD_03064 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
MHPLLIDD_03065 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
MHPLLIDD_03066 2.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
MHPLLIDD_03067 0.0 yesS K Transcriptional regulator
MHPLLIDD_03068 9.7e-129 E GDSL-like Lipase/Acylhydrolase
MHPLLIDD_03069 7.1e-129 yesU S Domain of unknown function (DUF1961)
MHPLLIDD_03070 5.2e-113 yesV S Protein of unknown function, DUF624
MHPLLIDD_03071 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MHPLLIDD_03072 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MHPLLIDD_03073 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
MHPLLIDD_03074 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
MHPLLIDD_03075 0.0 yetA
MHPLLIDD_03076 1.5e-288 lplA G Bacterial extracellular solute-binding protein
MHPLLIDD_03077 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MHPLLIDD_03078 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
MHPLLIDD_03079 8.9e-256 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MHPLLIDD_03080 6.7e-122 yetF S membrane
MHPLLIDD_03081 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MHPLLIDD_03082 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPLLIDD_03083 2.2e-34
MHPLLIDD_03084 5.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHPLLIDD_03085 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
MHPLLIDD_03086 2.6e-104 yetJ S Belongs to the BI1 family
MHPLLIDD_03087 8.3e-31 yetM CH FAD binding domain
MHPLLIDD_03088 3.6e-199 yetN S Protein of unknown function (DUF3900)
MHPLLIDD_03089 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MHPLLIDD_03090 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MHPLLIDD_03091 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
MHPLLIDD_03092 1.9e-172 yfnG 4.2.1.45 M dehydratase
MHPLLIDD_03093 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
MHPLLIDD_03094 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
MHPLLIDD_03095 3.3e-188 yfnD M Nucleotide-diphospho-sugar transferase
MHPLLIDD_03096 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
MHPLLIDD_03097 3.9e-133 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MHPLLIDD_03098 1.4e-240 yfnA E amino acid
MHPLLIDD_03099 1.1e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHPLLIDD_03100 1.1e-113 yfmS NT chemotaxis protein
MHPLLIDD_03101 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHPLLIDD_03102 3.4e-74 yfmQ S Uncharacterised protein from bacillus cereus group
MHPLLIDD_03103 4e-69 yfmP K transcriptional
MHPLLIDD_03104 1.5e-209 yfmO EGP Major facilitator Superfamily
MHPLLIDD_03105 2.1e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHPLLIDD_03106 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MHPLLIDD_03107 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
MHPLLIDD_03108 1.8e-187 yfmJ S N-terminal domain of oxidoreductase
MHPLLIDD_03109 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
MHPLLIDD_03110 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPLLIDD_03111 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPLLIDD_03112 2.7e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MHPLLIDD_03113 2.9e-24 S Protein of unknown function (DUF3212)
MHPLLIDD_03114 7.6e-58 yflT S Heat induced stress protein YflT
MHPLLIDD_03115 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
MHPLLIDD_03116 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
MHPLLIDD_03117 1.5e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MHPLLIDD_03118 8.9e-119 citT T response regulator
MHPLLIDD_03119 4.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
MHPLLIDD_03120 1.9e-226 citM C Citrate transporter
MHPLLIDD_03121 2.3e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MHPLLIDD_03122 2.1e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MHPLLIDD_03123 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MHPLLIDD_03124 6.4e-122 yflK S protein conserved in bacteria
MHPLLIDD_03125 4e-18 yflJ S Protein of unknown function (DUF2639)
MHPLLIDD_03126 4.1e-19 yflI
MHPLLIDD_03127 5.3e-50 yflH S Protein of unknown function (DUF3243)
MHPLLIDD_03128 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
MHPLLIDD_03129 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MHPLLIDD_03130 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MHPLLIDD_03131 6e-67 yhdN S Domain of unknown function (DUF1992)
MHPLLIDD_03132 3.1e-251 agcS_1 E Sodium alanine symporter
MHPLLIDD_03133 8.4e-25 yfkQ EG Spore germination protein
MHPLLIDD_03134 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MHPLLIDD_03135 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MHPLLIDD_03136 5.1e-133 treR K transcriptional
MHPLLIDD_03137 1.8e-124 yfkO C nitroreductase
MHPLLIDD_03138 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MHPLLIDD_03139 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
MHPLLIDD_03140 6.8e-207 ydiM EGP Major facilitator Superfamily
MHPLLIDD_03141 1.3e-28 yfkK S Belongs to the UPF0435 family
MHPLLIDD_03142 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHPLLIDD_03143 1.2e-49 yfkI S gas vesicle protein
MHPLLIDD_03144 4.8e-143 yihY S Belongs to the UPF0761 family
MHPLLIDD_03145 5e-08
MHPLLIDD_03146 2.6e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
MHPLLIDD_03147 1.8e-182 cax P COG0387 Ca2 H antiporter
MHPLLIDD_03148 1.2e-146 yfkD S YfkD-like protein
MHPLLIDD_03149 6e-149 yfkC M Mechanosensitive ion channel
MHPLLIDD_03150 5.4e-222 yfkA S YfkB-like domain
MHPLLIDD_03151 1.1e-26 yfjT
MHPLLIDD_03152 1.7e-153 pdaA G deacetylase
MHPLLIDD_03153 2.1e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MHPLLIDD_03154 1.7e-184 corA P Mediates influx of magnesium ions
MHPLLIDD_03155 2.2e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MHPLLIDD_03156 2e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHPLLIDD_03157 1.6e-39 S YfzA-like protein
MHPLLIDD_03158 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHPLLIDD_03159 1.1e-83 yfjM S Psort location Cytoplasmic, score
MHPLLIDD_03160 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHPLLIDD_03161 7.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHPLLIDD_03162 6.7e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHPLLIDD_03163 2.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHPLLIDD_03164 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MHPLLIDD_03165 9.8e-25 sspH S Belongs to the SspH family
MHPLLIDD_03166 4e-56 yfjF S UPF0060 membrane protein
MHPLLIDD_03167 1.1e-79 S Family of unknown function (DUF5381)
MHPLLIDD_03168 1.8e-101 yfjD S Family of unknown function (DUF5381)
MHPLLIDD_03169 4.5e-143 yfjC
MHPLLIDD_03170 9.2e-191 yfjB
MHPLLIDD_03171 7.4e-44 yfjA S Belongs to the WXG100 family
MHPLLIDD_03172 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MHPLLIDD_03173 1.6e-140 glvR K Helix-turn-helix domain, rpiR family
MHPLLIDD_03174 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MHPLLIDD_03175 1.1e-306 yfiB3 V ABC transporter
MHPLLIDD_03176 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHPLLIDD_03177 6.4e-64 mhqP S DoxX
MHPLLIDD_03178 5.7e-163 yfiE 1.13.11.2 S glyoxalase
MHPLLIDD_03179 1.5e-177 K AraC-like ligand binding domain
MHPLLIDD_03180 1.8e-262 iolT EGP Major facilitator Superfamily
MHPLLIDD_03181 8.4e-184 G Xylose isomerase
MHPLLIDD_03182 1.1e-233 S Oxidoreductase
MHPLLIDD_03184 1.1e-214 yxjM T Histidine kinase
MHPLLIDD_03185 3.2e-113 KT LuxR family transcriptional regulator
MHPLLIDD_03186 1.4e-170 V ABC transporter, ATP-binding protein
MHPLLIDD_03187 2e-206 V ABC-2 family transporter protein
MHPLLIDD_03188 2.6e-203 V COG0842 ABC-type multidrug transport system, permease component
MHPLLIDD_03189 8.3e-99 padR K transcriptional
MHPLLIDD_03190 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MHPLLIDD_03191 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MHPLLIDD_03192 7.1e-107 yfiR K Transcriptional regulator
MHPLLIDD_03193 1.5e-209 yfiS EGP Major facilitator Superfamily
MHPLLIDD_03194 3.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
MHPLLIDD_03195 3.4e-283 yfiU EGP Major facilitator Superfamily
MHPLLIDD_03196 5.8e-80 yfiV K transcriptional
MHPLLIDD_03197 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHPLLIDD_03198 1e-176 yfiY P ABC transporter substrate-binding protein
MHPLLIDD_03199 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPLLIDD_03200 2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHPLLIDD_03201 1.8e-167 yfhB 5.3.3.17 S PhzF family
MHPLLIDD_03202 1.5e-106 yfhC C nitroreductase
MHPLLIDD_03203 2.1e-25 yfhD S YfhD-like protein
MHPLLIDD_03205 1.6e-171 yfhF S nucleoside-diphosphate sugar epimerase
MHPLLIDD_03206 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
MHPLLIDD_03207 9.7e-52 yfhH S Protein of unknown function (DUF1811)
MHPLLIDD_03209 1.1e-209 yfhI EGP Major facilitator Superfamily
MHPLLIDD_03210 6.2e-20 sspK S reproduction
MHPLLIDD_03211 1.3e-44 yfhJ S WVELL protein
MHPLLIDD_03212 5.1e-90 batE T Bacterial SH3 domain homologues
MHPLLIDD_03213 3e-47 yfhL S SdpI/YhfL protein family
MHPLLIDD_03214 4.4e-171 yfhM S Alpha beta hydrolase
MHPLLIDD_03215 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MHPLLIDD_03216 0.0 yfhO S Bacterial membrane protein YfhO
MHPLLIDD_03217 5.5e-186 yfhP S membrane-bound metal-dependent
MHPLLIDD_03218 1e-211 mutY L A G-specific
MHPLLIDD_03219 6.9e-36 yfhS
MHPLLIDD_03220 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPLLIDD_03221 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
MHPLLIDD_03222 1.5e-37 ygaB S YgaB-like protein
MHPLLIDD_03223 1.3e-104 ygaC J Belongs to the UPF0374 family
MHPLLIDD_03224 1.8e-301 ygaD V ABC transporter
MHPLLIDD_03225 8.7e-180 ygaE S Membrane
MHPLLIDD_03226 1.2e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MHPLLIDD_03227 6.3e-87 bcp 1.11.1.15 O Peroxiredoxin
MHPLLIDD_03228 4e-80 perR P Belongs to the Fur family
MHPLLIDD_03229 1.1e-54 ygzB S UPF0295 protein
MHPLLIDD_03230 3.3e-166 ygxA S Nucleotidyltransferase-like
MHPLLIDD_03231 3.4e-39 S COG NOG14552 non supervised orthologous group
MHPLLIDD_03236 7.8e-08
MHPLLIDD_03244 2e-08
MHPLLIDD_03248 2.7e-143 spo0M S COG4326 Sporulation control protein
MHPLLIDD_03249 1.2e-26
MHPLLIDD_03250 1.6e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
MHPLLIDD_03251 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MHPLLIDD_03252 1.9e-266 ygaK C Berberine and berberine like
MHPLLIDD_03254 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MHPLLIDD_03255 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MHPLLIDD_03256 1.7e-171 ssuA M Sulfonate ABC transporter
MHPLLIDD_03257 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHPLLIDD_03258 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MHPLLIDD_03260 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHPLLIDD_03261 4.1e-78 ygaO
MHPLLIDD_03262 4.4e-29 K Transcriptional regulator
MHPLLIDD_03264 7.9e-114 yhzB S B3/4 domain
MHPLLIDD_03265 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MHPLLIDD_03266 4.4e-177 yhbB S Putative amidase domain
MHPLLIDD_03267 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHPLLIDD_03268 1.2e-109 yhbD K Protein of unknown function (DUF4004)
MHPLLIDD_03269 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MHPLLIDD_03270 8.5e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
MHPLLIDD_03271 0.0 prkA T Ser protein kinase
MHPLLIDD_03272 2.5e-225 yhbH S Belongs to the UPF0229 family
MHPLLIDD_03273 2.2e-76 yhbI K DNA-binding transcription factor activity
MHPLLIDD_03274 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
MHPLLIDD_03275 3.1e-271 yhcA EGP Major facilitator Superfamily
MHPLLIDD_03276 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
MHPLLIDD_03277 2.8e-37 yhcC
MHPLLIDD_03278 2e-55
MHPLLIDD_03279 6.6e-60 yhcF K Transcriptional regulator
MHPLLIDD_03280 1.6e-123 yhcG V ABC transporter, ATP-binding protein
MHPLLIDD_03281 7.7e-166 yhcH V ABC transporter, ATP-binding protein
MHPLLIDD_03282 5.6e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHPLLIDD_03283 1e-30 cspB K Cold-shock protein
MHPLLIDD_03284 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
MHPLLIDD_03285 1.9e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
MHPLLIDD_03286 4.1e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHPLLIDD_03287 1.1e-77 S Protein of unknown function (DUF2812)
MHPLLIDD_03288 1.2e-49 K Transcriptional regulator PadR-like family
MHPLLIDD_03289 2e-41 yhcM
MHPLLIDD_03290 1.3e-67 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHPLLIDD_03291 2.5e-167 yhcP
MHPLLIDD_03292 5.2e-100 yhcQ M Spore coat protein
MHPLLIDD_03293 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
MHPLLIDD_03294 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MHPLLIDD_03295 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MHPLLIDD_03296 9.3e-68 yhcU S Family of unknown function (DUF5365)
MHPLLIDD_03297 9.9e-68 yhcV S COG0517 FOG CBS domain
MHPLLIDD_03298 4.6e-120 yhcW 5.4.2.6 S hydrolase
MHPLLIDD_03299 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MHPLLIDD_03300 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHPLLIDD_03301 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MHPLLIDD_03302 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MHPLLIDD_03303 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHPLLIDD_03304 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MHPLLIDD_03305 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MHPLLIDD_03306 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
MHPLLIDD_03307 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHPLLIDD_03308 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
MHPLLIDD_03309 1.2e-38 yhdB S YhdB-like protein
MHPLLIDD_03310 4.8e-54 yhdC S Protein of unknown function (DUF3889)
MHPLLIDD_03311 1.5e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MHPLLIDD_03312 1e-75 nsrR K Transcriptional regulator
MHPLLIDD_03313 3.6e-237 ygxB M Conserved TM helix
MHPLLIDD_03314 6.3e-276 ycgB S Stage V sporulation protein R
MHPLLIDD_03315 5e-254 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MHPLLIDD_03316 1e-139 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MHPLLIDD_03317 3.8e-162 citR K Transcriptional regulator
MHPLLIDD_03318 1.3e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
MHPLLIDD_03319 2.7e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPLLIDD_03320 3.4e-250 yhdG E amino acid
MHPLLIDD_03321 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MHPLLIDD_03322 7.2e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHPLLIDD_03323 2e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHPLLIDD_03324 8.1e-45 yhdK S Sigma-M inhibitor protein
MHPLLIDD_03325 1.5e-200 yhdL S Sigma factor regulator N-terminal
MHPLLIDD_03326 1e-84 sigM K Belongs to the sigma-70 factor family. ECF subfamily
MHPLLIDD_03327 8.3e-190 yhdN C Aldo keto reductase
MHPLLIDD_03328 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MHPLLIDD_03329 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MHPLLIDD_03330 4.7e-74 cueR K transcriptional
MHPLLIDD_03331 4.4e-222 yhdR 2.6.1.1 E Aminotransferase
MHPLLIDD_03332 2.1e-239 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
MHPLLIDD_03333 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHPLLIDD_03334 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHPLLIDD_03335 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MHPLLIDD_03337 1.6e-202 yhdY M Mechanosensitive ion channel
MHPLLIDD_03338 4.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MHPLLIDD_03339 5.3e-137 yheN G deacetylase
MHPLLIDD_03340 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MHPLLIDD_03341 3.7e-225 nhaC C Na H antiporter
MHPLLIDD_03342 5.4e-82 nhaX T Belongs to the universal stress protein A family
MHPLLIDD_03343 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHPLLIDD_03344 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHPLLIDD_03345 7.6e-109 yheG GM NAD(P)H-binding
MHPLLIDD_03346 6.3e-28 sspB S spore protein
MHPLLIDD_03347 1.3e-36 yheE S Family of unknown function (DUF5342)
MHPLLIDD_03348 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MHPLLIDD_03349 4.3e-216 yheC HJ YheC/D like ATP-grasp
MHPLLIDD_03350 1.8e-201 yheB S Belongs to the UPF0754 family
MHPLLIDD_03351 9.5e-48 yheA S Belongs to the UPF0342 family
MHPLLIDD_03352 3.1e-206 yhaZ L DNA alkylation repair enzyme
MHPLLIDD_03353 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
MHPLLIDD_03354 3.9e-292 hemZ H coproporphyrinogen III oxidase
MHPLLIDD_03355 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
MHPLLIDD_03356 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
MHPLLIDD_03358 3.3e-130 yhaR 5.3.3.18 I enoyl-CoA hydratase
MHPLLIDD_03359 1.1e-26 S YhzD-like protein
MHPLLIDD_03360 1.2e-166 yhaQ S ABC transporter, ATP-binding protein
MHPLLIDD_03361 1.6e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MHPLLIDD_03362 2.2e-224 yhaO L DNA repair exonuclease
MHPLLIDD_03363 0.0 yhaN L AAA domain
MHPLLIDD_03364 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
MHPLLIDD_03365 1.6e-21 yhaL S Sporulation protein YhaL
MHPLLIDD_03366 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHPLLIDD_03367 8.7e-90 yhaK S Putative zincin peptidase
MHPLLIDD_03368 1.3e-54 yhaI S Protein of unknown function (DUF1878)
MHPLLIDD_03369 1e-113 hpr K Negative regulator of protease production and sporulation
MHPLLIDD_03370 7e-39 yhaH S YtxH-like protein
MHPLLIDD_03371 3.6e-80 trpP S Tryptophan transporter TrpP
MHPLLIDD_03372 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MHPLLIDD_03373 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MHPLLIDD_03374 4.6e-137 ecsA V transporter (ATP-binding protein)
MHPLLIDD_03375 1.8e-215 ecsB U ABC transporter
MHPLLIDD_03376 1.4e-114 ecsC S EcsC protein family
MHPLLIDD_03377 5.7e-230 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MHPLLIDD_03378 2.7e-231 yhfA C membrane
MHPLLIDD_03379 7.9e-27 1.15.1.2 C Rubrerythrin
MHPLLIDD_03380 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MHPLLIDD_03381 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MHPLLIDD_03382 1.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MHPLLIDD_03383 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MHPLLIDD_03384 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MHPLLIDD_03385 5.4e-101 yhgD K Transcriptional regulator
MHPLLIDD_03386 2.5e-237 yhgE S YhgE Pip N-terminal domain protein
MHPLLIDD_03387 4.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHPLLIDD_03388 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
MHPLLIDD_03389 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
MHPLLIDD_03390 1.7e-72 3.4.13.21 S ASCH
MHPLLIDD_03391 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHPLLIDD_03392 2e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MHPLLIDD_03393 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
MHPLLIDD_03394 1.9e-110 yhfK GM NmrA-like family
MHPLLIDD_03395 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MHPLLIDD_03396 1.9e-65 yhfM
MHPLLIDD_03397 3.5e-241 yhfN 3.4.24.84 O Peptidase M48
MHPLLIDD_03398 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
MHPLLIDD_03399 3.1e-75 VY92_01935 K acetyltransferase
MHPLLIDD_03400 5.4e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
MHPLLIDD_03401 4.3e-159 yfmC M Periplasmic binding protein
MHPLLIDD_03402 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MHPLLIDD_03403 5.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
MHPLLIDD_03404 6.4e-268 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MHPLLIDD_03405 6.5e-91 bioY S BioY family
MHPLLIDD_03406 1.7e-182 hemAT NT chemotaxis protein
MHPLLIDD_03407 4.7e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MHPLLIDD_03408 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPLLIDD_03409 1.3e-32 yhzC S IDEAL
MHPLLIDD_03410 4.2e-109 comK K Competence transcription factor
MHPLLIDD_03411 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
MHPLLIDD_03412 7.8e-42 yhjA S Excalibur calcium-binding domain
MHPLLIDD_03413 1.3e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHPLLIDD_03414 6.9e-27 yhjC S Protein of unknown function (DUF3311)
MHPLLIDD_03415 6.7e-60 yhjD
MHPLLIDD_03416 3.4e-109 yhjE S SNARE associated Golgi protein
MHPLLIDD_03417 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
MHPLLIDD_03418 2.4e-278 yhjG CH FAD binding domain
MHPLLIDD_03419 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
MHPLLIDD_03420 4.5e-214 glcP G Major Facilitator Superfamily
MHPLLIDD_03421 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
MHPLLIDD_03422 4.5e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
MHPLLIDD_03423 7.7e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MHPLLIDD_03424 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
MHPLLIDD_03425 5.1e-199 abrB S membrane
MHPLLIDD_03426 7.9e-211 EGP Transmembrane secretion effector
MHPLLIDD_03427 0.0 S Sugar transport-related sRNA regulator N-term
MHPLLIDD_03428 2.7e-33 yhjQ C COG1145 Ferredoxin
MHPLLIDD_03429 1.1e-77 yhjR S Rubrerythrin
MHPLLIDD_03430 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MHPLLIDD_03431 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MHPLLIDD_03432 6.9e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MHPLLIDD_03433 0.0 sbcC L COG0419 ATPase involved in DNA repair
MHPLLIDD_03434 1.1e-49 yisB V COG1403 Restriction endonuclease
MHPLLIDD_03435 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
MHPLLIDD_03436 3e-66 gerPE S Spore germination protein GerPE
MHPLLIDD_03437 6.3e-24 gerPD S Spore germination protein
MHPLLIDD_03438 1.8e-54 gerPC S Spore germination protein
MHPLLIDD_03439 4e-34 gerPB S cell differentiation
MHPLLIDD_03440 1.9e-33 gerPA S Spore germination protein
MHPLLIDD_03441 1.5e-22 yisI S Spo0E like sporulation regulatory protein
MHPLLIDD_03442 1.1e-172 cotH M Spore Coat
MHPLLIDD_03443 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MHPLLIDD_03444 3.9e-57 yisL S UPF0344 protein
MHPLLIDD_03445 0.0 wprA O Belongs to the peptidase S8 family
MHPLLIDD_03446 2.1e-102 yisN S Protein of unknown function (DUF2777)
MHPLLIDD_03447 0.0 asnO 6.3.5.4 E Asparagine synthase
MHPLLIDD_03448 3.9e-87 yizA S Damage-inducible protein DinB
MHPLLIDD_03449 2.8e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
MHPLLIDD_03450 1.5e-242 yisQ V Mate efflux family protein
MHPLLIDD_03451 1.2e-160 yisR K Transcriptional regulator
MHPLLIDD_03452 1.5e-183 purR K helix_turn _helix lactose operon repressor
MHPLLIDD_03453 1.5e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
MHPLLIDD_03454 7e-92 yisT S DinB family
MHPLLIDD_03455 1.9e-107 argO S Lysine exporter protein LysE YggA
MHPLLIDD_03456 1.8e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHPLLIDD_03457 4e-36 mcbG S Pentapeptide repeats (9 copies)
MHPLLIDD_03458 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MHPLLIDD_03459 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MHPLLIDD_03460 2.5e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MHPLLIDD_03461 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MHPLLIDD_03462 5.3e-119 comB 3.1.3.71 H Belongs to the ComB family
MHPLLIDD_03463 5.4e-141 yitD 4.4.1.19 S synthase
MHPLLIDD_03464 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHPLLIDD_03465 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MHPLLIDD_03466 1.5e-228 yitG EGP Major facilitator Superfamily
MHPLLIDD_03467 2e-160 yitH K Acetyltransferase (GNAT) domain
MHPLLIDD_03468 7.8e-79 yjcF S Acetyltransferase (GNAT) domain
MHPLLIDD_03469 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MHPLLIDD_03470 5.6e-54 yajQ S Belongs to the UPF0234 family
MHPLLIDD_03471 6.9e-161 cvfB S protein conserved in bacteria
MHPLLIDD_03472 8.5e-94
MHPLLIDD_03473 1.4e-170
MHPLLIDD_03474 1.5e-97 S Sporulation delaying protein SdpA
MHPLLIDD_03475 1.5e-58 K Transcriptional regulator PadR-like family
MHPLLIDD_03476 2e-95
MHPLLIDD_03477 1.4e-44 yitR S Domain of unknown function (DUF3784)
MHPLLIDD_03478 2.2e-311 nprB 3.4.24.28 E Peptidase M4
MHPLLIDD_03479 8.4e-159 yitS S protein conserved in bacteria
MHPLLIDD_03480 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MHPLLIDD_03481 5e-73 ipi S Intracellular proteinase inhibitor
MHPLLIDD_03482 1.2e-17 S Protein of unknown function (DUF3813)
MHPLLIDD_03483 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MHPLLIDD_03484 1e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MHPLLIDD_03485 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
MHPLLIDD_03486 1.5e-22 pilT S Proteolipid membrane potential modulator
MHPLLIDD_03487 6e-266 yitY C D-arabinono-1,4-lactone oxidase
MHPLLIDD_03488 1.7e-88 norB G Major Facilitator Superfamily
MHPLLIDD_03489 1.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MHPLLIDD_03490 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MHPLLIDD_03491 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MHPLLIDD_03492 6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MHPLLIDD_03493 9.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MHPLLIDD_03494 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MHPLLIDD_03495 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHPLLIDD_03496 9.5e-28 yjzC S YjzC-like protein
MHPLLIDD_03497 2.3e-16 yjzD S Protein of unknown function (DUF2929)
MHPLLIDD_03498 6.8e-141 yjaU I carboxylic ester hydrolase activity
MHPLLIDD_03499 1.8e-101 yjaV
MHPLLIDD_03500 1.1e-183 med S Transcriptional activator protein med
MHPLLIDD_03501 4.7e-25 comZ S ComZ
MHPLLIDD_03502 2.7e-22 yjzB
MHPLLIDD_03503 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHPLLIDD_03504 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHPLLIDD_03505 1.7e-150 yjaZ O Zn-dependent protease
MHPLLIDD_03506 1.8e-184 appD P Belongs to the ABC transporter superfamily
MHPLLIDD_03507 6.5e-187 appF E Belongs to the ABC transporter superfamily
MHPLLIDD_03508 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
MHPLLIDD_03509 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPLLIDD_03510 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPLLIDD_03511 6.5e-147 yjbA S Belongs to the UPF0736 family
MHPLLIDD_03512 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MHPLLIDD_03513 0.0 oppA E ABC transporter substrate-binding protein
MHPLLIDD_03514 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPLLIDD_03515 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPLLIDD_03516 1.5e-197 oppD P Belongs to the ABC transporter superfamily
MHPLLIDD_03517 5.5e-172 oppF E Belongs to the ABC transporter superfamily
MHPLLIDD_03518 1.8e-210 yjbB EGP Major Facilitator Superfamily
MHPLLIDD_03519 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHPLLIDD_03520 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHPLLIDD_03521 6e-112 yjbE P Integral membrane protein TerC family
MHPLLIDD_03522 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHPLLIDD_03523 2.1e-221 yjbF S Competence protein
MHPLLIDD_03524 0.0 pepF E oligoendopeptidase F
MHPLLIDD_03525 1.8e-20
MHPLLIDD_03527 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MHPLLIDD_03528 1.1e-71 yjbI S Bacterial-like globin
MHPLLIDD_03529 3.8e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHPLLIDD_03530 1e-99 yjbK S protein conserved in bacteria
MHPLLIDD_03531 1.6e-61 yjbL S Belongs to the UPF0738 family
MHPLLIDD_03532 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
MHPLLIDD_03533 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHPLLIDD_03534 2.3e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MHPLLIDD_03535 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MHPLLIDD_03536 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHPLLIDD_03537 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MHPLLIDD_03538 9.3e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
MHPLLIDD_03539 1.2e-213 thiO 1.4.3.19 E Glycine oxidase
MHPLLIDD_03540 2.6e-29 thiS H thiamine diphosphate biosynthetic process
MHPLLIDD_03541 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MHPLLIDD_03542 5.1e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MHPLLIDD_03543 2.2e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MHPLLIDD_03544 9.5e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MHPLLIDD_03545 5.9e-54 yjbX S Spore coat protein
MHPLLIDD_03546 4.4e-82 cotZ S Spore coat protein
MHPLLIDD_03547 7.6e-96 cotY S Spore coat protein Z
MHPLLIDD_03548 1.6e-72 cotX S Spore Coat Protein X and V domain
MHPLLIDD_03549 8.8e-24 cotW
MHPLLIDD_03550 1.1e-54 cotV S Spore Coat Protein X and V domain
MHPLLIDD_03551 4.3e-56 yjcA S Protein of unknown function (DUF1360)
MHPLLIDD_03554 2.9e-38 spoVIF S Stage VI sporulation protein F
MHPLLIDD_03555 0.0 yjcD 3.6.4.12 L DNA helicase
MHPLLIDD_03556 1.7e-38
MHPLLIDD_03557 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHPLLIDD_03558 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MHPLLIDD_03559 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
MHPLLIDD_03560 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MHPLLIDD_03561 4.2e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MHPLLIDD_03562 7.7e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
MHPLLIDD_03563 5.4e-212 yjcL S Protein of unknown function (DUF819)
MHPLLIDD_03566 7.8e-190 S Putative amidase domain
MHPLLIDD_03567 2.6e-44 yjcN
MHPLLIDD_03570 8.5e-81 L Transposase
MHPLLIDD_03571 1.6e-72 yjcP
MHPLLIDD_03572 4.1e-49 S YjcQ protein
MHPLLIDD_03573 1.1e-92 yqaS L DNA packaging
MHPLLIDD_03574 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
MHPLLIDD_03575 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
MHPLLIDD_03577 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
MHPLLIDD_03578 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
MHPLLIDD_03579 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
MHPLLIDD_03580 4.5e-49 yjdF S Protein of unknown function (DUF2992)
MHPLLIDD_03581 4.5e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
MHPLLIDD_03583 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHPLLIDD_03584 4.2e-29 S Domain of unknown function (DUF4177)
MHPLLIDD_03585 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
MHPLLIDD_03586 1.4e-173 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHPLLIDD_03588 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
MHPLLIDD_03589 1.2e-82 S Protein of unknown function (DUF2690)
MHPLLIDD_03590 2.3e-20 yjfB S Putative motility protein
MHPLLIDD_03591 2.7e-163 yjfC O Predicted Zn-dependent protease (DUF2268)
MHPLLIDD_03592 1.2e-45 T PhoQ Sensor
MHPLLIDD_03593 8.9e-104 yjgB S Domain of unknown function (DUF4309)
MHPLLIDD_03594 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MHPLLIDD_03595 4.3e-95 yjgD S Protein of unknown function (DUF1641)
MHPLLIDD_03596 8.7e-07 S Domain of unknown function (DUF4352)
MHPLLIDD_03597 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
MHPLLIDD_03599 1.9e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
MHPLLIDD_03600 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MHPLLIDD_03601 8.2e-30
MHPLLIDD_03602 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MHPLLIDD_03603 1.9e-122 ybbM S transport system, permease component
MHPLLIDD_03604 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
MHPLLIDD_03605 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
MHPLLIDD_03606 2.8e-93 yjlB S Cupin domain
MHPLLIDD_03607 7.1e-66 yjlC S Protein of unknown function (DUF1641)
MHPLLIDD_03608 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
MHPLLIDD_03609 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
MHPLLIDD_03610 5.8e-250 yjmB G symporter YjmB
MHPLLIDD_03611 4.3e-194 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MHPLLIDD_03612 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
MHPLLIDD_03613 2.3e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MHPLLIDD_03614 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPLLIDD_03615 3.7e-227 exuT G Sugar (and other) transporter
MHPLLIDD_03616 2.3e-184 exuR K transcriptional
MHPLLIDD_03617 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MHPLLIDD_03618 4.6e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MHPLLIDD_03619 7.4e-130 MA20_18170 S membrane transporter protein
MHPLLIDD_03620 2.3e-78 yjoA S DinB family
MHPLLIDD_03621 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
MHPLLIDD_03622 1e-212 S response regulator aspartate phosphatase
MHPLLIDD_03624 5.2e-37 S YCII-related domain
MHPLLIDD_03625 6.8e-165 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
MHPLLIDD_03626 1.8e-60 yjqA S Bacterial PH domain
MHPLLIDD_03627 2.1e-111 yjqB S Pfam:DUF867
MHPLLIDD_03628 9.8e-160 ydbD P Catalase
MHPLLIDD_03629 4.3e-109 xkdA E IrrE N-terminal-like domain
MHPLLIDD_03630 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
MHPLLIDD_03632 5e-156 xkdB K sequence-specific DNA binding
MHPLLIDD_03633 9.2e-118 xkdC L Bacterial dnaA protein
MHPLLIDD_03636 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
MHPLLIDD_03637 2.2e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MHPLLIDD_03638 5.3e-139 xtmA L phage terminase small subunit
MHPLLIDD_03639 1.4e-253 xtmB S phage terminase, large subunit
MHPLLIDD_03640 6e-285 yqbA S portal protein
MHPLLIDD_03641 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MHPLLIDD_03642 1.3e-168 xkdG S Phage capsid family
MHPLLIDD_03643 5.5e-65 yqbG S Protein of unknown function (DUF3199)
MHPLLIDD_03644 8.7e-65 yqbH S Domain of unknown function (DUF3599)
MHPLLIDD_03645 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
MHPLLIDD_03646 1.9e-77 xkdJ
MHPLLIDD_03647 2.5e-256 xkdK S Phage tail sheath C-terminal domain
MHPLLIDD_03648 6.1e-76 xkdM S Phage tail tube protein
MHPLLIDD_03649 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
MHPLLIDD_03650 0.0 xkdO L Transglycosylase SLT domain
MHPLLIDD_03651 4.1e-121 xkdP S Lysin motif
MHPLLIDD_03652 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
MHPLLIDD_03653 2.1e-39 xkdR S Protein of unknown function (DUF2577)
MHPLLIDD_03654 3.1e-69 xkdS S Protein of unknown function (DUF2634)
MHPLLIDD_03655 6.7e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MHPLLIDD_03656 1.2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MHPLLIDD_03657 1.5e-40
MHPLLIDD_03658 1e-261
MHPLLIDD_03659 5.4e-53 xkdW S XkdW protein
MHPLLIDD_03660 5.5e-22 xkdX
MHPLLIDD_03661 1.7e-151 xepA
MHPLLIDD_03662 6.2e-39 xhlA S Haemolysin XhlA
MHPLLIDD_03663 9.3e-40 xhlB S SPP1 phage holin
MHPLLIDD_03664 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MHPLLIDD_03665 6.7e-23 spoIISB S Stage II sporulation protein SB
MHPLLIDD_03666 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MHPLLIDD_03667 5.8e-175 pit P phosphate transporter
MHPLLIDD_03668 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
MHPLLIDD_03669 4e-240 steT E amino acid
MHPLLIDD_03670 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MHPLLIDD_03671 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHPLLIDD_03672 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MHPLLIDD_03674 7.5e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHPLLIDD_03675 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
MHPLLIDD_03676 2.5e-152 dppA E D-aminopeptidase
MHPLLIDD_03677 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPLLIDD_03678 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPLLIDD_03679 1.3e-187 dppD P Belongs to the ABC transporter superfamily
MHPLLIDD_03680 0.0 dppE E ABC transporter substrate-binding protein
MHPLLIDD_03682 1.3e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MHPLLIDD_03683 2.3e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MHPLLIDD_03684 2.7e-163 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHPLLIDD_03685 9.4e-186 ykfD E Belongs to the ABC transporter superfamily
MHPLLIDD_03686 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
MHPLLIDD_03687 2e-160 ykgA E Amidinotransferase
MHPLLIDD_03688 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MHPLLIDD_03689 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MHPLLIDD_03690 5.5e-09
MHPLLIDD_03691 7.8e-129 ykjA S Protein of unknown function (DUF421)
MHPLLIDD_03692 4.8e-96 ykkA S Protein of unknown function (DUF664)
MHPLLIDD_03693 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHPLLIDD_03694 3.5e-55 ykkC P Multidrug resistance protein
MHPLLIDD_03695 7e-50 ykkD P Multidrug resistance protein
MHPLLIDD_03696 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MHPLLIDD_03697 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHPLLIDD_03698 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHPLLIDD_03699 1.3e-70 ohrA O Organic hydroperoxide resistance protein
MHPLLIDD_03700 4.8e-73 ohrR K COG1846 Transcriptional regulators
MHPLLIDD_03701 2.4e-71 ohrB O Organic hydroperoxide resistance protein
MHPLLIDD_03702 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
MHPLLIDD_03703 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHPLLIDD_03704 1.6e-174 isp O Belongs to the peptidase S8 family
MHPLLIDD_03705 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHPLLIDD_03706 5.3e-136 ykoC P Cobalt transport protein
MHPLLIDD_03707 2.2e-304 P ABC transporter, ATP-binding protein
MHPLLIDD_03708 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
MHPLLIDD_03709 1.6e-108 ykoF S YKOF-related Family
MHPLLIDD_03710 7.9e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHPLLIDD_03711 1.4e-240 ykoH 2.7.13.3 T Histidine kinase
MHPLLIDD_03712 9.9e-110 ykoI S Peptidase propeptide and YPEB domain
MHPLLIDD_03713 8.3e-85 ykoJ S Peptidase propeptide and YPEB domain
MHPLLIDD_03716 2.2e-222 mgtE P Acts as a magnesium transporter
MHPLLIDD_03717 1.4e-53 tnrA K transcriptional
MHPLLIDD_03718 5.9e-18
MHPLLIDD_03719 6.9e-26 ykoL
MHPLLIDD_03720 1.3e-81 mhqR K transcriptional
MHPLLIDD_03721 3.1e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MHPLLIDD_03722 1.4e-98 ykoP G polysaccharide deacetylase
MHPLLIDD_03723 3.5e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
MHPLLIDD_03724 0.0 ykoS
MHPLLIDD_03725 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MHPLLIDD_03726 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MHPLLIDD_03727 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MHPLLIDD_03728 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
MHPLLIDD_03729 3.5e-109 ykoX S membrane-associated protein
MHPLLIDD_03730 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MHPLLIDD_03731 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPLLIDD_03732 9.1e-116 rsgI S Anti-sigma factor N-terminus
MHPLLIDD_03733 1.9e-26 sspD S small acid-soluble spore protein
MHPLLIDD_03734 7.3e-124 ykrK S Domain of unknown function (DUF1836)
MHPLLIDD_03735 3.5e-155 htpX O Belongs to the peptidase M48B family
MHPLLIDD_03736 1.1e-232 ktrB P COG0168 Trk-type K transport systems, membrane components
MHPLLIDD_03737 1.2e-10 ydfR S Protein of unknown function (DUF421)
MHPLLIDD_03738 4.1e-18 ykzE
MHPLLIDD_03739 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MHPLLIDD_03740 0.0 kinE 2.7.13.3 T Histidine kinase
MHPLLIDD_03741 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHPLLIDD_03743 1.4e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MHPLLIDD_03744 2.4e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MHPLLIDD_03745 1e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MHPLLIDD_03746 1.5e-230 mtnE 2.6.1.83 E Aminotransferase
MHPLLIDD_03747 1.4e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MHPLLIDD_03748 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MHPLLIDD_03749 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MHPLLIDD_03750 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MHPLLIDD_03751 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
MHPLLIDD_03752 6.4e-09 S Spo0E like sporulation regulatory protein
MHPLLIDD_03753 1.8e-64 eag
MHPLLIDD_03754 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
MHPLLIDD_03755 1.3e-75 ykvE K transcriptional
MHPLLIDD_03756 2.5e-125 motB N Flagellar motor protein
MHPLLIDD_03757 1e-137 motA N flagellar motor
MHPLLIDD_03758 0.0 clpE O Belongs to the ClpA ClpB family
MHPLLIDD_03759 2.6e-178 ykvI S membrane
MHPLLIDD_03760 9.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MHPLLIDD_03761 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MHPLLIDD_03762 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MHPLLIDD_03763 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MHPLLIDD_03764 2e-61 ykvN K Transcriptional regulator
MHPLLIDD_03765 2.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
MHPLLIDD_03766 9.9e-216 ykvP 3.5.1.28 M Glycosyl transferases group 1
MHPLLIDD_03767 3.5e-35 3.5.1.104 M LysM domain
MHPLLIDD_03768 1.4e-162 G Glycosyl hydrolases family 18
MHPLLIDD_03769 5.6e-46 ykvR S Protein of unknown function (DUF3219)
MHPLLIDD_03770 6e-25 ykvS S protein conserved in bacteria
MHPLLIDD_03771 2.8e-28
MHPLLIDD_03772 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
MHPLLIDD_03773 3.8e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHPLLIDD_03774 1.6e-88 stoA CO thiol-disulfide
MHPLLIDD_03775 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MHPLLIDD_03776 2.3e-09
MHPLLIDD_03777 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MHPLLIDD_03778 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
MHPLLIDD_03780 2.2e-127 glcT K antiterminator
MHPLLIDD_03781 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MHPLLIDD_03782 2.1e-39 ptsH G phosphocarrier protein HPr
MHPLLIDD_03783 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHPLLIDD_03784 7.2e-39 splA S Transcriptional regulator
MHPLLIDD_03785 7.5e-202 splB 4.1.99.14 L Spore photoproduct lyase
MHPLLIDD_03786 3.2e-127 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHPLLIDD_03787 1.6e-261 mcpC NT chemotaxis protein
MHPLLIDD_03788 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MHPLLIDD_03789 8e-124 ykwD J protein with SCP PR1 domains
MHPLLIDD_03790 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
MHPLLIDD_03791 0.0 pilS 2.7.13.3 T Histidine kinase
MHPLLIDD_03792 8e-224 patA 2.6.1.1 E Aminotransferase
MHPLLIDD_03793 2.2e-15
MHPLLIDD_03794 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
MHPLLIDD_03795 1.7e-84 ykyB S YkyB-like protein
MHPLLIDD_03796 1.7e-235 ykuC EGP Major facilitator Superfamily
MHPLLIDD_03797 1.5e-86 ykuD S protein conserved in bacteria
MHPLLIDD_03798 1.6e-165 ykuE S Metallophosphoesterase
MHPLLIDD_03799 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHPLLIDD_03800 5.2e-234 ykuI T Diguanylate phosphodiesterase
MHPLLIDD_03801 3.9e-37 ykuJ S protein conserved in bacteria
MHPLLIDD_03802 4.4e-94 ykuK S Ribonuclease H-like
MHPLLIDD_03803 3.9e-27 ykzF S Antirepressor AbbA
MHPLLIDD_03804 1.6e-76 ykuL S CBS domain
MHPLLIDD_03805 3.5e-168 ccpC K Transcriptional regulator
MHPLLIDD_03806 8.5e-84 fld C Flavodoxin domain
MHPLLIDD_03807 3e-175 ykuO
MHPLLIDD_03808 3.9e-78 fld C Flavodoxin
MHPLLIDD_03809 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MHPLLIDD_03810 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MHPLLIDD_03811 9e-37 ykuS S Belongs to the UPF0180 family
MHPLLIDD_03812 8.8e-142 ykuT M Mechanosensitive ion channel
MHPLLIDD_03813 3.9e-101 ykuU O Alkyl hydroperoxide reductase
MHPLLIDD_03814 7e-80 ykuV CO thiol-disulfide
MHPLLIDD_03815 5.8e-95 rok K Repressor of ComK
MHPLLIDD_03816 4.2e-146 yknT
MHPLLIDD_03817 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MHPLLIDD_03818 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MHPLLIDD_03819 8.1e-246 moeA 2.10.1.1 H molybdopterin
MHPLLIDD_03820 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MHPLLIDD_03821 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MHPLLIDD_03822 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MHPLLIDD_03823 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHPLLIDD_03824 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHPLLIDD_03825 1e-117 yknW S Yip1 domain
MHPLLIDD_03826 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MHPLLIDD_03827 2.5e-124 macB V ABC transporter, ATP-binding protein
MHPLLIDD_03828 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
MHPLLIDD_03829 3.1e-136 fruR K Transcriptional regulator
MHPLLIDD_03830 3.1e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MHPLLIDD_03831 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MHPLLIDD_03832 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MHPLLIDD_03833 8.1e-39 ykoA
MHPLLIDD_03834 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHPLLIDD_03835 1.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHPLLIDD_03836 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MHPLLIDD_03837 1.1e-12 S Uncharacterized protein YkpC
MHPLLIDD_03838 7.7e-183 mreB D Rod-share determining protein MreBH
MHPLLIDD_03839 3.3e-43 abrB K of stationary sporulation gene expression
MHPLLIDD_03840 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MHPLLIDD_03841 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
MHPLLIDD_03842 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
MHPLLIDD_03843 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MHPLLIDD_03844 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHPLLIDD_03845 8.2e-31 ykzG S Belongs to the UPF0356 family
MHPLLIDD_03846 1.4e-147 ykrA S hydrolases of the HAD superfamily
MHPLLIDD_03847 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHPLLIDD_03849 2e-115 recN L Putative cell-wall binding lipoprotein
MHPLLIDD_03850 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHPLLIDD_03851 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHPLLIDD_03852 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHPLLIDD_03853 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHPLLIDD_03854 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
MHPLLIDD_03855 3.5e-277 speA 4.1.1.19 E Arginine
MHPLLIDD_03856 1.6e-42 yktA S Belongs to the UPF0223 family
MHPLLIDD_03857 2.1e-117 yktB S Belongs to the UPF0637 family
MHPLLIDD_03858 7.1e-26 ykzI
MHPLLIDD_03859 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
MHPLLIDD_03860 2.2e-76 ykzC S Acetyltransferase (GNAT) family
MHPLLIDD_03861 8.7e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MHPLLIDD_03862 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
MHPLLIDD_03863 0.0 ylaA
MHPLLIDD_03864 2.7e-42 ylaB
MHPLLIDD_03865 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
MHPLLIDD_03866 7.1e-12 sigC S Putative zinc-finger
MHPLLIDD_03867 4.1e-38 ylaE
MHPLLIDD_03868 8.2e-22 S Family of unknown function (DUF5325)
MHPLLIDD_03869 0.0 typA T GTP-binding protein TypA
MHPLLIDD_03870 4.2e-47 ylaH S YlaH-like protein
MHPLLIDD_03871 2.5e-32 ylaI S protein conserved in bacteria
MHPLLIDD_03872 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHPLLIDD_03873 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MHPLLIDD_03874 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MHPLLIDD_03875 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
MHPLLIDD_03876 8.7e-44 ylaN S Belongs to the UPF0358 family
MHPLLIDD_03877 4.5e-214 ftsW D Belongs to the SEDS family
MHPLLIDD_03878 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MHPLLIDD_03879 7.7e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MHPLLIDD_03880 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHPLLIDD_03881 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MHPLLIDD_03882 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHPLLIDD_03883 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MHPLLIDD_03884 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MHPLLIDD_03885 3.4e-166 ctaG S cytochrome c oxidase
MHPLLIDD_03886 7e-62 ylbA S YugN-like family
MHPLLIDD_03887 2.6e-74 ylbB T COG0517 FOG CBS domain
MHPLLIDD_03888 9.6e-200 ylbC S protein with SCP PR1 domains
MHPLLIDD_03889 4.1e-63 ylbD S Putative coat protein
MHPLLIDD_03890 2.5e-36 ylbE S YlbE-like protein
MHPLLIDD_03891 1.8e-75 ylbF S Belongs to the UPF0342 family
MHPLLIDD_03892 3.7e-38 ylbG S UPF0298 protein
MHPLLIDD_03893 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
MHPLLIDD_03894 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHPLLIDD_03895 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
MHPLLIDD_03896 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
MHPLLIDD_03897 6.8e-187 ylbL T Belongs to the peptidase S16 family
MHPLLIDD_03898 4e-234 ylbM S Belongs to the UPF0348 family
MHPLLIDD_03900 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
MHPLLIDD_03901 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MHPLLIDD_03902 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MHPLLIDD_03903 1.5e-88 ylbP K n-acetyltransferase
MHPLLIDD_03904 6.1e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHPLLIDD_03905 3.2e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MHPLLIDD_03906 2.9e-78 mraZ K Belongs to the MraZ family
MHPLLIDD_03907 4.7e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHPLLIDD_03908 3.7e-44 ftsL D Essential cell division protein
MHPLLIDD_03909 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MHPLLIDD_03910 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MHPLLIDD_03911 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHPLLIDD_03912 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHPLLIDD_03913 1.9e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHPLLIDD_03914 5.7e-186 spoVE D Belongs to the SEDS family
MHPLLIDD_03915 6.7e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHPLLIDD_03916 5.3e-167 murB 1.3.1.98 M cell wall formation
MHPLLIDD_03917 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHPLLIDD_03918 4.1e-103 ylxW S protein conserved in bacteria
MHPLLIDD_03919 4.4e-90 ylxX S protein conserved in bacteria
MHPLLIDD_03920 2.8e-55 sbp S small basic protein
MHPLLIDD_03921 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHPLLIDD_03922 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHPLLIDD_03923 0.0 bpr O COG1404 Subtilisin-like serine proteases
MHPLLIDD_03924 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MHPLLIDD_03925 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPLLIDD_03926 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPLLIDD_03927 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MHPLLIDD_03928 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
MHPLLIDD_03929 2.4e-37 ylmC S sporulation protein
MHPLLIDD_03930 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MHPLLIDD_03931 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MHPLLIDD_03932 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHPLLIDD_03933 1.6e-39 yggT S membrane
MHPLLIDD_03934 8.2e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MHPLLIDD_03935 2.6e-67 divIVA D Cell division initiation protein
MHPLLIDD_03936 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHPLLIDD_03937 1.3e-63 dksA T COG1734 DnaK suppressor protein
MHPLLIDD_03938 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHPLLIDD_03939 3.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MHPLLIDD_03940 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHPLLIDD_03941 2.6e-231 pyrP F Xanthine uracil
MHPLLIDD_03942 8.5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MHPLLIDD_03943 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHPLLIDD_03944 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MHPLLIDD_03945 0.0 carB 6.3.5.5 F Belongs to the CarB family
MHPLLIDD_03946 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MHPLLIDD_03947 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHPLLIDD_03948 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHPLLIDD_03949 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHPLLIDD_03951 1.7e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MHPLLIDD_03952 1.2e-178 cysP P phosphate transporter
MHPLLIDD_03953 1.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MHPLLIDD_03954 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MHPLLIDD_03955 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MHPLLIDD_03956 2.2e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MHPLLIDD_03957 6.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MHPLLIDD_03958 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MHPLLIDD_03959 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MHPLLIDD_03960 3.1e-156 yloC S stress-induced protein
MHPLLIDD_03961 1.5e-40 ylzA S Belongs to the UPF0296 family
MHPLLIDD_03962 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MHPLLIDD_03963 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHPLLIDD_03964 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHPLLIDD_03965 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHPLLIDD_03966 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHPLLIDD_03967 5.2e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHPLLIDD_03968 5.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHPLLIDD_03969 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MHPLLIDD_03970 1.6e-140 stp 3.1.3.16 T phosphatase
MHPLLIDD_03971 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MHPLLIDD_03972 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHPLLIDD_03973 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MHPLLIDD_03974 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
MHPLLIDD_03975 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MHPLLIDD_03976 5.5e-59 asp S protein conserved in bacteria
MHPLLIDD_03977 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
MHPLLIDD_03978 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MHPLLIDD_03979 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
MHPLLIDD_03980 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHPLLIDD_03981 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MHPLLIDD_03982 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHPLLIDD_03983 2.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MHPLLIDD_03984 1.1e-127 IQ reductase
MHPLLIDD_03985 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHPLLIDD_03986 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHPLLIDD_03987 0.0 smc D Required for chromosome condensation and partitioning
MHPLLIDD_03988 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHPLLIDD_03989 3.5e-85
MHPLLIDD_03990 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHPLLIDD_03991 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHPLLIDD_03992 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MHPLLIDD_03993 4.5e-36 ylqC S Belongs to the UPF0109 family
MHPLLIDD_03994 6.3e-61 ylqD S YlqD protein
MHPLLIDD_03995 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHPLLIDD_03996 7.8e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MHPLLIDD_03997 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHPLLIDD_03998 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHPLLIDD_03999 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHPLLIDD_04000 4.3e-287 ylqG
MHPLLIDD_04001 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MHPLLIDD_04002 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MHPLLIDD_04003 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MHPLLIDD_04004 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MHPLLIDD_04005 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHPLLIDD_04006 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MHPLLIDD_04007 2.5e-169 xerC L tyrosine recombinase XerC
MHPLLIDD_04008 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHPLLIDD_04009 4.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHPLLIDD_04010 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MHPLLIDD_04011 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MHPLLIDD_04012 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
MHPLLIDD_04013 1.9e-31 fliE N Flagellar hook-basal body
MHPLLIDD_04014 1.6e-254 fliF N The M ring may be actively involved in energy transduction
MHPLLIDD_04015 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHPLLIDD_04016 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MHPLLIDD_04017 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MHPLLIDD_04018 1.5e-69 fliJ N Flagellar biosynthesis chaperone
MHPLLIDD_04019 2.2e-36 ylxF S MgtE intracellular N domain
MHPLLIDD_04020 5.2e-217 fliK N Flagellar hook-length control protein
MHPLLIDD_04021 1.7e-72 flgD N Flagellar basal body rod modification protein
MHPLLIDD_04022 8.2e-140 flgG N Flagellar basal body rod
MHPLLIDD_04023 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
MHPLLIDD_04024 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHPLLIDD_04025 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MHPLLIDD_04026 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
MHPLLIDD_04027 2.7e-96 fliZ N Flagellar biosynthesis protein, FliO
MHPLLIDD_04028 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
MHPLLIDD_04029 2.2e-36 fliQ N Role in flagellar biosynthesis
MHPLLIDD_04030 3.6e-132 fliR N Flagellar biosynthetic protein FliR
MHPLLIDD_04031 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHPLLIDD_04032 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHPLLIDD_04033 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
MHPLLIDD_04034 4.1e-156 flhG D Belongs to the ParA family
MHPLLIDD_04035 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MHPLLIDD_04036 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MHPLLIDD_04037 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
MHPLLIDD_04038 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MHPLLIDD_04039 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MHPLLIDD_04040 9.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHPLLIDD_04041 3.1e-76 ylxL
MHPLLIDD_04042 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
MHPLLIDD_04043 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHPLLIDD_04044 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MHPLLIDD_04045 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHPLLIDD_04046 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHPLLIDD_04047 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
MHPLLIDD_04048 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MHPLLIDD_04049 7.7e-233 rasP M zinc metalloprotease
MHPLLIDD_04050 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHPLLIDD_04051 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHPLLIDD_04052 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
MHPLLIDD_04053 1.1e-203 nusA K Participates in both transcription termination and antitermination
MHPLLIDD_04054 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
MHPLLIDD_04055 3.1e-47 ylxQ J ribosomal protein
MHPLLIDD_04056 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHPLLIDD_04057 3e-44 ylxP S protein conserved in bacteria
MHPLLIDD_04058 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHPLLIDD_04059 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHPLLIDD_04060 1.1e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MHPLLIDD_04061 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHPLLIDD_04062 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MHPLLIDD_04063 6.1e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MHPLLIDD_04064 4.4e-233 pepR S Belongs to the peptidase M16 family
MHPLLIDD_04065 2.6e-42 ymxH S YlmC YmxH family
MHPLLIDD_04066 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MHPLLIDD_04067 6.3e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MHPLLIDD_04068 1.2e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHPLLIDD_04069 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MHPLLIDD_04070 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHPLLIDD_04071 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHPLLIDD_04072 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MHPLLIDD_04073 4.4e-32 S YlzJ-like protein
MHPLLIDD_04074 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MHPLLIDD_04075 1.4e-133 ymfC K Transcriptional regulator
MHPLLIDD_04076 3.8e-205 ymfD EGP Major facilitator Superfamily
MHPLLIDD_04077 2e-233 ymfF S Peptidase M16
MHPLLIDD_04078 1.4e-242 ymfH S zinc protease
MHPLLIDD_04079 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MHPLLIDD_04080 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
MHPLLIDD_04081 2.7e-143 ymfK S Protein of unknown function (DUF3388)
MHPLLIDD_04082 7.3e-116 ymfM S protein conserved in bacteria
MHPLLIDD_04083 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHPLLIDD_04084 1.3e-235 cinA 3.5.1.42 S Belongs to the CinA family
MHPLLIDD_04085 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHPLLIDD_04086 1e-215 pbpX V Beta-lactamase
MHPLLIDD_04087 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
MHPLLIDD_04088 1.9e-152 ymdB S protein conserved in bacteria
MHPLLIDD_04089 1.2e-36 spoVS S Stage V sporulation protein S
MHPLLIDD_04090 3e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MHPLLIDD_04091 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MHPLLIDD_04092 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MHPLLIDD_04093 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MHPLLIDD_04094 2.2e-88 cotE S Spore coat protein
MHPLLIDD_04095 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHPLLIDD_04096 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHPLLIDD_04097 2.3e-70 S Regulatory protein YrvL
MHPLLIDD_04099 1.2e-97 ymcC S Membrane
MHPLLIDD_04100 4.4e-109 pksA K Transcriptional regulator
MHPLLIDD_04101 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
MHPLLIDD_04102 7.5e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MHPLLIDD_04103 2.4e-186 pksD Q Acyl transferase domain
MHPLLIDD_04104 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MHPLLIDD_04105 1.4e-37 acpK IQ Phosphopantetheine attachment site
MHPLLIDD_04106 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHPLLIDD_04107 1.3e-245 pksG 2.3.3.10 I synthase
MHPLLIDD_04108 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
MHPLLIDD_04109 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
MHPLLIDD_04110 0.0 rhiB IQ polyketide synthase
MHPLLIDD_04111 0.0 pfaA Q Polyketide synthase of type I
MHPLLIDD_04112 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
MHPLLIDD_04113 0.0 dhbF IQ polyketide synthase
MHPLLIDD_04114 0.0 pks13 HQ Beta-ketoacyl synthase
MHPLLIDD_04115 6.3e-232 cypA C Cytochrome P450
MHPLLIDD_04116 4.4e-61 ymzB
MHPLLIDD_04117 8.1e-162 ymaE S Metallo-beta-lactamase superfamily
MHPLLIDD_04118 1.2e-180 aprX O Belongs to the peptidase S8 family
MHPLLIDD_04121 6.2e-29 S Phage terminase, small subunit
MHPLLIDD_04124 6.9e-45 S endonuclease activity
MHPLLIDD_04125 7.2e-134 S Phage Terminase
MHPLLIDD_04126 1.6e-106 S Phage portal protein
MHPLLIDD_04127 1.9e-55 S Caudovirus prohead serine protease
MHPLLIDD_04128 6.8e-87 S Phage capsid family
MHPLLIDD_04130 1.4e-21 S DNA packaging
MHPLLIDD_04131 1.8e-11 S Phage head-tail joining protein
MHPLLIDD_04132 7.4e-14 S Bacteriophage HK97-gp10, putative tail-component
MHPLLIDD_04133 2.5e-07
MHPLLIDD_04134 1.6e-40 S Phage tail tube protein
MHPLLIDD_04136 2.3e-174 D Phage tail tape measure protein
MHPLLIDD_04137 6e-177 S Phage tail protein
MHPLLIDD_04138 1.8e-147 S Phage minor structural protein
MHPLLIDD_04139 1.1e-23
MHPLLIDD_04140 5.4e-77 S N-acetylmuramoyl-L-alanine amidase activity
MHPLLIDD_04141 6.7e-12
MHPLLIDD_04144 1.9e-09 S SPP1 phage holin
MHPLLIDD_04145 1.2e-106 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 CBM50 M Glycosyl hydrolases family 25
MHPLLIDD_04146 1.2e-97 S Phage integrase family
MHPLLIDD_04147 1.7e-171 A Pre-toxin TG
MHPLLIDD_04148 3.1e-66 S Immunity protein 70
MHPLLIDD_04149 2.2e-27 S Domain of unknown function (DUF4935)
MHPLLIDD_04151 5.4e-13 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MHPLLIDD_04157 2.8e-56 traC L Domain of unknown function (DUF1738)
MHPLLIDD_04158 7e-148 S DNA gyrase/topoisomerase IV, subunit A
MHPLLIDD_04159 1.2e-184 S DNA gyrase B
MHPLLIDD_04160 4e-15 repA S Replication initiator protein A (RepA) N-terminus
MHPLLIDD_04162 1.5e-10 tdk 2.7.1.21 F Psort location Cytoplasmic, score
MHPLLIDD_04168 3.3e-18 S Endodeoxyribonuclease RusA
MHPLLIDD_04169 3.7e-22 2.7.4.8 F Guanylate kinase homologues.
MHPLLIDD_04173 0.0 S Bacterial DNA polymerase III alpha subunit
MHPLLIDD_04175 4.4e-10 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
MHPLLIDD_04177 1.8e-46 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHPLLIDD_04180 1.3e-06 yfbR S HD containing hydrolase-like enzyme
MHPLLIDD_04182 2.3e-17 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
MHPLLIDD_04183 1.9e-15 K Transcriptional regulator
MHPLLIDD_04184 3.6e-87 S exonuclease activity
MHPLLIDD_04186 1.7e-89 S DNA primase activity
MHPLLIDD_04187 2.7e-110 S DNA helicase activity
MHPLLIDD_04188 1.3e-15
MHPLLIDD_04189 2.6e-24
MHPLLIDD_04191 1e-39
MHPLLIDD_04193 3.4e-10 fld C flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
MHPLLIDD_04194 1.2e-103 S Ribonucleotide reductase, small chain
MHPLLIDD_04195 2.8e-276 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
MHPLLIDD_04196 2.5e-64 S AAA domain
MHPLLIDD_04199 8.2e-48 F Nucleoside 2-deoxyribosyltransferase
MHPLLIDD_04200 2.5e-34
MHPLLIDD_04202 2e-07
MHPLLIDD_04203 1.5e-31 yxcD S Protein of unknown function (DUF2653)
MHPLLIDD_04205 8.1e-20
MHPLLIDD_04206 2e-41 XK27_03185 S Phosphoribosyl-ATP pyrophosphohydrolase
MHPLLIDD_04209 1.7e-52
MHPLLIDD_04210 3.6e-73 L integrase family
MHPLLIDD_04213 1.6e-22 yocH 3.5.1.28 M 3D domain
MHPLLIDD_04214 1.2e-68 lig 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP dependent DNA ligase domain
MHPLLIDD_04216 1.1e-81
MHPLLIDD_04218 8.6e-138 S response regulator aspartate phosphatase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)