ORF_ID e_value Gene_name EC_number CAZy COGs Description
MDGJMAFB_00001 2.8e-37 yhcC
MDGJMAFB_00002 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
MDGJMAFB_00003 1e-124 yhcA EGP Major facilitator Superfamily
MDGJMAFB_00004 5.8e-127 yhcA EGP Major facilitator Superfamily
MDGJMAFB_00005 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
MDGJMAFB_00006 2.2e-76 yhbI K DNA-binding transcription factor activity
MDGJMAFB_00007 2.5e-225 yhbH S Belongs to the UPF0229 family
MDGJMAFB_00008 0.0 prkA T Ser protein kinase
MDGJMAFB_00009 8.5e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
MDGJMAFB_00010 7.8e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MDGJMAFB_00011 7.9e-109 yhbD K Protein of unknown function (DUF4004)
MDGJMAFB_00012 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDGJMAFB_00013 2.4e-175 yhbB S Putative amidase domain
MDGJMAFB_00014 2.3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MDGJMAFB_00015 7.9e-114 yhzB S B3/4 domain
MDGJMAFB_00017 4.4e-29 K Transcriptional regulator
MDGJMAFB_00018 4.1e-78 ygaO
MDGJMAFB_00019 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDGJMAFB_00021 1.2e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MDGJMAFB_00022 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MDGJMAFB_00023 2.1e-169 ssuA M Sulfonate ABC transporter
MDGJMAFB_00024 3.9e-146 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MDGJMAFB_00025 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MDGJMAFB_00027 2.2e-262 ygaK C Berberine and berberine like
MDGJMAFB_00028 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MDGJMAFB_00029 5e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
MDGJMAFB_00030 1.2e-26
MDGJMAFB_00031 5.9e-143 spo0M S COG4326 Sporulation control protein
MDGJMAFB_00035 2e-08
MDGJMAFB_00043 7.8e-08
MDGJMAFB_00048 3.4e-39 S COG NOG14552 non supervised orthologous group
MDGJMAFB_00049 4.3e-166 ygxA S Nucleotidyltransferase-like
MDGJMAFB_00050 2.8e-55 ygzB S UPF0295 protein
MDGJMAFB_00051 4e-80 perR P Belongs to the Fur family
MDGJMAFB_00052 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
MDGJMAFB_00053 1.4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MDGJMAFB_00054 8.7e-180 ygaE S Membrane
MDGJMAFB_00055 1.2e-300 ygaD V ABC transporter
MDGJMAFB_00056 1.3e-104 ygaC J Belongs to the UPF0374 family
MDGJMAFB_00057 1.5e-37 ygaB S YgaB-like protein
MDGJMAFB_00058 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
MDGJMAFB_00059 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDGJMAFB_00060 6.9e-36 yfhS
MDGJMAFB_00061 1.6e-209 mutY L A G-specific
MDGJMAFB_00062 1.2e-185 yfhP S membrane-bound metal-dependent
MDGJMAFB_00063 0.0 yfhO S Bacterial membrane protein YfhO
MDGJMAFB_00064 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MDGJMAFB_00065 6.7e-172 yfhM S Alpha beta hydrolase
MDGJMAFB_00066 3.5e-51 yfhL S SdpI/YhfL protein family
MDGJMAFB_00067 2.4e-87 batE T Bacterial SH3 domain homologues
MDGJMAFB_00068 1.3e-44 yfhJ S WVELL protein
MDGJMAFB_00069 6.2e-20 sspK S reproduction
MDGJMAFB_00070 1.5e-209 yfhI EGP Major facilitator Superfamily
MDGJMAFB_00071 3.2e-50 yfhH S Protein of unknown function (DUF1811)
MDGJMAFB_00072 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
MDGJMAFB_00073 2e-169 yfhF S nucleoside-diphosphate sugar epimerase
MDGJMAFB_00075 2.1e-25 yfhD S YfhD-like protein
MDGJMAFB_00076 3.9e-107 yfhC C nitroreductase
MDGJMAFB_00077 5.6e-166 yfhB 5.3.3.17 S PhzF family
MDGJMAFB_00078 1.5e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDGJMAFB_00079 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDGJMAFB_00080 3.9e-176 yfiY P ABC transporter substrate-binding protein
MDGJMAFB_00081 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDGJMAFB_00082 4.9e-79 yfiV K transcriptional
MDGJMAFB_00083 5e-282 yfiU EGP Major facilitator Superfamily
MDGJMAFB_00084 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
MDGJMAFB_00085 5.3e-218 yfiS EGP Major facilitator Superfamily
MDGJMAFB_00086 1.9e-107 yfiR K Transcriptional regulator
MDGJMAFB_00087 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MDGJMAFB_00088 9.9e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MDGJMAFB_00089 8.3e-99 padR K transcriptional
MDGJMAFB_00090 1.4e-201 V COG0842 ABC-type multidrug transport system, permease component
MDGJMAFB_00091 5.2e-207 V ABC-2 family transporter protein
MDGJMAFB_00092 9.2e-167 V ABC transporter, ATP-binding protein
MDGJMAFB_00093 7.1e-113 KT LuxR family transcriptional regulator
MDGJMAFB_00094 3.6e-213 yxjM T Histidine kinase
MDGJMAFB_00096 6.3e-162 yfiE 1.13.11.2 S glyoxalase
MDGJMAFB_00097 6.4e-64 mhqP S DoxX
MDGJMAFB_00098 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MDGJMAFB_00099 1.3e-307 yfiB3 V ABC transporter
MDGJMAFB_00100 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDGJMAFB_00101 1e-139 glvR K Helix-turn-helix domain, rpiR family
MDGJMAFB_00102 2.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MDGJMAFB_00103 2.6e-44 yfjA S Belongs to the WXG100 family
MDGJMAFB_00104 2.7e-190 yfjB
MDGJMAFB_00105 4.1e-144 yfjC
MDGJMAFB_00106 5.3e-101 yfjD S Family of unknown function (DUF5381)
MDGJMAFB_00107 2.7e-78 S Family of unknown function (DUF5381)
MDGJMAFB_00108 5.2e-56 yfjF S UPF0060 membrane protein
MDGJMAFB_00109 1.2e-25 sspH S Belongs to the SspH family
MDGJMAFB_00110 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MDGJMAFB_00111 4.7e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MDGJMAFB_00112 6e-195 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDGJMAFB_00113 4.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MDGJMAFB_00114 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDGJMAFB_00115 3e-29 yfjL
MDGJMAFB_00116 3.4e-82 yfjM S Psort location Cytoplasmic, score
MDGJMAFB_00117 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDGJMAFB_00118 3.9e-44 S YfzA-like protein
MDGJMAFB_00119 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDGJMAFB_00120 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MDGJMAFB_00121 1.7e-184 corA P Mediates influx of magnesium ions
MDGJMAFB_00122 9.5e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MDGJMAFB_00123 1.7e-153 pdaA G deacetylase
MDGJMAFB_00124 1.1e-26 yfjT
MDGJMAFB_00125 5.4e-222 yfkA S YfkB-like domain
MDGJMAFB_00126 6e-149 yfkC M Mechanosensitive ion channel
MDGJMAFB_00127 1.2e-146 yfkD S YfkD-like protein
MDGJMAFB_00128 1.8e-182 cax P COG0387 Ca2 H antiporter
MDGJMAFB_00129 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
MDGJMAFB_00130 5e-08
MDGJMAFB_00131 1.3e-143 yihY S Belongs to the UPF0761 family
MDGJMAFB_00132 2.4e-50 yfkI S gas vesicle protein
MDGJMAFB_00133 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDGJMAFB_00134 1.3e-28 yfkK S Belongs to the UPF0435 family
MDGJMAFB_00135 6.8e-207 ydiM EGP Major facilitator Superfamily
MDGJMAFB_00136 4.3e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
MDGJMAFB_00137 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MDGJMAFB_00138 1.1e-124 yfkO C nitroreductase
MDGJMAFB_00139 1.8e-133 treR K transcriptional
MDGJMAFB_00140 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MDGJMAFB_00141 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDGJMAFB_00142 3.4e-283 yfkQ EG Spore germination protein
MDGJMAFB_00143 5.1e-207 yfkR S spore germination
MDGJMAFB_00145 1.3e-193 E Spore germination protein
MDGJMAFB_00146 9.1e-251 agcS_1 E Sodium alanine symporter
MDGJMAFB_00147 6e-67 yhdN S Domain of unknown function (DUF1992)
MDGJMAFB_00148 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MDGJMAFB_00149 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MDGJMAFB_00150 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
MDGJMAFB_00151 5.3e-50 yflH S Protein of unknown function (DUF3243)
MDGJMAFB_00152 4.1e-19 yflI
MDGJMAFB_00153 4e-18 yflJ S Protein of unknown function (DUF2639)
MDGJMAFB_00154 6.4e-122 yflK S protein conserved in bacteria
MDGJMAFB_00155 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MDGJMAFB_00156 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MDGJMAFB_00157 4.6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MDGJMAFB_00158 5.5e-226 citM C Citrate transporter
MDGJMAFB_00159 8.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
MDGJMAFB_00160 2.2e-117 citT T response regulator
MDGJMAFB_00161 1.7e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MDGJMAFB_00162 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
MDGJMAFB_00163 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
MDGJMAFB_00164 7.6e-58 yflT S Heat induced stress protein YflT
MDGJMAFB_00165 2.9e-24 S Protein of unknown function (DUF3212)
MDGJMAFB_00166 7.9e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MDGJMAFB_00167 6.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDGJMAFB_00168 9e-168 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDGJMAFB_00169 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
MDGJMAFB_00170 1.8e-187 yfmJ S N-terminal domain of oxidoreductase
MDGJMAFB_00171 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
MDGJMAFB_00172 1e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MDGJMAFB_00173 1.2e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MDGJMAFB_00174 9.5e-209 yfmO EGP Major facilitator Superfamily
MDGJMAFB_00175 2.8e-70 yfmP K transcriptional
MDGJMAFB_00176 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
MDGJMAFB_00177 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MDGJMAFB_00178 1.1e-113 yfmS NT chemotaxis protein
MDGJMAFB_00179 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDGJMAFB_00180 8.4e-241 yfnA E amino acid
MDGJMAFB_00181 3.4e-103 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MDGJMAFB_00182 6.6e-205 fsr P COG0477 Permeases of the major facilitator superfamily
MDGJMAFB_00183 2.3e-189 yfnD M Nucleotide-diphospho-sugar transferase
MDGJMAFB_00184 7.9e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
MDGJMAFB_00185 7.9e-179 yfnF M Nucleotide-diphospho-sugar transferase
MDGJMAFB_00186 7.1e-172 yfnG 4.2.1.45 M dehydratase
MDGJMAFB_00187 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
MDGJMAFB_00188 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MDGJMAFB_00189 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MDGJMAFB_00190 1.8e-198 yetN S Protein of unknown function (DUF3900)
MDGJMAFB_00191 2.4e-30 yetM CH FAD binding domain
MDGJMAFB_00192 5.3e-105 yetJ S Belongs to the BI1 family
MDGJMAFB_00193 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
MDGJMAFB_00194 2.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDGJMAFB_00195 2.4e-34
MDGJMAFB_00196 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDGJMAFB_00197 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MDGJMAFB_00198 4e-122 yetF S membrane
MDGJMAFB_00199 3.5e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MDGJMAFB_00200 1.4e-161 lplC G Binding-protein-dependent transport system inner membrane component
MDGJMAFB_00201 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MDGJMAFB_00202 2.1e-290 lplA G Bacterial extracellular solute-binding protein
MDGJMAFB_00203 0.0 yetA
MDGJMAFB_00204 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
MDGJMAFB_00205 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
MDGJMAFB_00206 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MDGJMAFB_00207 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MDGJMAFB_00208 8.8e-113 yesV S Protein of unknown function, DUF624
MDGJMAFB_00209 2.3e-127 yesU S Domain of unknown function (DUF1961)
MDGJMAFB_00210 2.7e-131 E GDSL-like Lipase/Acylhydrolase
MDGJMAFB_00211 0.0 yesS K Transcriptional regulator
MDGJMAFB_00212 2.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
MDGJMAFB_00213 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
MDGJMAFB_00214 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
MDGJMAFB_00215 2.1e-246 yesO G Bacterial extracellular solute-binding protein
MDGJMAFB_00216 5.2e-201 yesN K helix_turn_helix, arabinose operon control protein
MDGJMAFB_00217 0.0 yesM 2.7.13.3 T Histidine kinase
MDGJMAFB_00218 4.5e-101 yesL S Protein of unknown function, DUF624
MDGJMAFB_00219 7.9e-102 yesJ K Acetyltransferase (GNAT) family
MDGJMAFB_00220 5.2e-104 cotJC P Spore Coat
MDGJMAFB_00221 1.5e-45 cotJB S CotJB protein
MDGJMAFB_00222 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
MDGJMAFB_00223 1.3e-151 yesF GM NAD(P)H-binding
MDGJMAFB_00224 1.8e-80 yesE S SnoaL-like domain
MDGJMAFB_00225 1.3e-102 dhaR3 K Transcriptional regulator
MDGJMAFB_00227 2.7e-126 yeeN K transcriptional regulatory protein
MDGJMAFB_00229 2.5e-211 S Tetratricopeptide repeat
MDGJMAFB_00230 2.3e-50
MDGJMAFB_00231 1.4e-53
MDGJMAFB_00232 1.2e-121 3.4.24.40 CO amine dehydrogenase activity
MDGJMAFB_00234 0.0 L nucleic acid phosphodiester bond hydrolysis
MDGJMAFB_00235 1.7e-52 S Protein of unknown function, DUF600
MDGJMAFB_00236 2.3e-57 S Protein of unknown function, DUF600
MDGJMAFB_00237 1.9e-11 S Protein of unknown function, DUF600
MDGJMAFB_00238 1.3e-54
MDGJMAFB_00240 5.1e-107 S WLM domain
MDGJMAFB_00241 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
MDGJMAFB_00242 1.9e-95 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MDGJMAFB_00243 5.6e-270 hsdM 2.1.1.72 V Type I restriction-modification system
MDGJMAFB_00244 5.2e-70 hsdS2 2.1.1.72 V type I restriction modification DNA specificity domain
MDGJMAFB_00245 4.1e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDGJMAFB_00246 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MDGJMAFB_00247 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MDGJMAFB_00248 2.5e-147 yerO K Transcriptional regulator
MDGJMAFB_00249 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDGJMAFB_00250 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDGJMAFB_00251 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDGJMAFB_00252 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDGJMAFB_00253 1.6e-123 sapB S MgtC SapB transporter
MDGJMAFB_00254 1.1e-194 yerI S homoserine kinase type II (protein kinase fold)
MDGJMAFB_00255 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
MDGJMAFB_00256 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDGJMAFB_00257 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MDGJMAFB_00258 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MDGJMAFB_00259 1.5e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
MDGJMAFB_00260 4.8e-51 yerC S protein conserved in bacteria
MDGJMAFB_00261 1.1e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
MDGJMAFB_00262 0.0 yerA 3.5.4.2 F adenine deaminase
MDGJMAFB_00263 7.1e-28 S Protein of unknown function (DUF2892)
MDGJMAFB_00264 1e-229 yjeH E Amino acid permease
MDGJMAFB_00265 1e-72 K helix_turn_helix ASNC type
MDGJMAFB_00266 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
MDGJMAFB_00267 7.8e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MDGJMAFB_00268 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MDGJMAFB_00269 4.2e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MDGJMAFB_00270 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MDGJMAFB_00271 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDGJMAFB_00272 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDGJMAFB_00273 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDGJMAFB_00274 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MDGJMAFB_00275 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDGJMAFB_00276 5.5e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MDGJMAFB_00277 3.7e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MDGJMAFB_00278 8e-28 yebG S NETI protein
MDGJMAFB_00279 4e-93 yebE S UPF0316 protein
MDGJMAFB_00281 4.4e-117 yebC M Membrane
MDGJMAFB_00282 7.8e-212 pbuG S permease
MDGJMAFB_00283 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MDGJMAFB_00284 0.0 yebA E COG1305 Transglutaminase-like enzymes
MDGJMAFB_00285 3.1e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MDGJMAFB_00286 1.9e-175 yeaC S COG0714 MoxR-like ATPases
MDGJMAFB_00287 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDGJMAFB_00288 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
MDGJMAFB_00289 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MDGJMAFB_00290 2.8e-174 yeaA S Protein of unknown function (DUF4003)
MDGJMAFB_00291 3.1e-158 ydjP I Alpha/beta hydrolase family
MDGJMAFB_00292 1.4e-34 ydjO S Cold-inducible protein YdjO
MDGJMAFB_00293 1.1e-155 ydjN U Involved in the tonB-independent uptake of proteins
MDGJMAFB_00294 4.5e-64 ydjM M Lytic transglycolase
MDGJMAFB_00295 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MDGJMAFB_00296 2.9e-257 iolT EGP Major facilitator Superfamily
MDGJMAFB_00297 1e-195 S Ion transport 2 domain protein
MDGJMAFB_00298 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
MDGJMAFB_00299 2e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
MDGJMAFB_00300 1.3e-177 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDGJMAFB_00301 9.2e-102 pspA KT Phage shock protein A
MDGJMAFB_00302 1.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
MDGJMAFB_00303 1.5e-250 gutA G MFS/sugar transport protein
MDGJMAFB_00304 8.5e-201 gutB 1.1.1.14 E Dehydrogenase
MDGJMAFB_00305 0.0 K NB-ARC domain
MDGJMAFB_00306 1.5e-151 ydjC S Abhydrolase domain containing 18
MDGJMAFB_00307 3.7e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDGJMAFB_00308 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDGJMAFB_00309 1.3e-128 ydiL S CAAX protease self-immunity
MDGJMAFB_00310 2.9e-27 ydiK S Domain of unknown function (DUF4305)
MDGJMAFB_00311 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MDGJMAFB_00312 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MDGJMAFB_00313 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDGJMAFB_00314 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MDGJMAFB_00315 0.0 ydiF S ABC transporter
MDGJMAFB_00316 3e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDGJMAFB_00317 1.8e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MDGJMAFB_00318 3.4e-126 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MDGJMAFB_00319 3.8e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MDGJMAFB_00320 4.5e-180 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MDGJMAFB_00322 7.8e-08
MDGJMAFB_00323 3.4e-39 S COG NOG14552 non supervised orthologous group
MDGJMAFB_00326 6.1e-157 ydhU P Catalase
MDGJMAFB_00327 1.8e-214 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MDGJMAFB_00328 9.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MDGJMAFB_00329 2.3e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MDGJMAFB_00330 1.1e-132 ydhQ K UTRA
MDGJMAFB_00331 4.7e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDGJMAFB_00332 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDGJMAFB_00333 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
MDGJMAFB_00334 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MDGJMAFB_00335 4.6e-200 pbuE EGP Major facilitator Superfamily
MDGJMAFB_00336 2.5e-98 ydhK M Protein of unknown function (DUF1541)
MDGJMAFB_00337 6.2e-182 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDGJMAFB_00338 3.3e-80 K Acetyltransferase (GNAT) domain
MDGJMAFB_00340 8.7e-68 frataxin S Domain of unknown function (DU1801)
MDGJMAFB_00341 3.1e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MDGJMAFB_00342 1.6e-123
MDGJMAFB_00343 1.3e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MDGJMAFB_00344 4.8e-243 ydhD M Glycosyl hydrolase
MDGJMAFB_00345 6.5e-122 ydhC K FCD
MDGJMAFB_00346 1.2e-121 ydhB S membrane transporter protein
MDGJMAFB_00347 2.5e-209 tcaB EGP Major facilitator Superfamily
MDGJMAFB_00348 2.4e-69 ydgJ K Winged helix DNA-binding domain
MDGJMAFB_00349 1e-113 drgA C nitroreductase
MDGJMAFB_00350 0.0 ydgH S drug exporters of the RND superfamily
MDGJMAFB_00351 1.4e-78 K helix_turn_helix multiple antibiotic resistance protein
MDGJMAFB_00352 4.3e-89 dinB S DinB family
MDGJMAFB_00353 1.2e-250 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MDGJMAFB_00354 6.8e-298 expZ S ABC transporter
MDGJMAFB_00355 1e-84 yycN 2.3.1.128 K Acetyltransferase
MDGJMAFB_00356 4.8e-52 S DoxX-like family
MDGJMAFB_00357 1.3e-97 K Bacterial regulatory proteins, tetR family
MDGJMAFB_00358 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
MDGJMAFB_00359 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
MDGJMAFB_00360 6.5e-75 cotP O Belongs to the small heat shock protein (HSP20) family
MDGJMAFB_00361 1.5e-121 ydfS S Protein of unknown function (DUF421)
MDGJMAFB_00362 4.4e-118 ydfR S Protein of unknown function (DUF421)
MDGJMAFB_00364 6.3e-29
MDGJMAFB_00365 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
MDGJMAFB_00366 4.1e-56 traF CO Thioredoxin
MDGJMAFB_00367 3.4e-62 mhqP S DoxX
MDGJMAFB_00368 4e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
MDGJMAFB_00369 2.8e-111 ydfN C nitroreductase
MDGJMAFB_00370 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDGJMAFB_00371 7.3e-144 K Bacterial transcription activator, effector binding domain
MDGJMAFB_00372 7.2e-116 S Protein of unknown function (DUF554)
MDGJMAFB_00373 1.6e-171 S Alpha/beta hydrolase family
MDGJMAFB_00374 0.0 ydfJ S drug exporters of the RND superfamily
MDGJMAFB_00375 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDGJMAFB_00376 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
MDGJMAFB_00378 2.9e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MDGJMAFB_00379 1e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
MDGJMAFB_00380 5e-116 ydfE S Flavin reductase like domain
MDGJMAFB_00381 2.3e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDGJMAFB_00382 7.2e-156 ydfC EG EamA-like transporter family
MDGJMAFB_00383 6.8e-147 ydfB J GNAT acetyltransferase
MDGJMAFB_00384 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MDGJMAFB_00385 8.2e-57 arsR K transcriptional
MDGJMAFB_00386 3.2e-104 ydeS K Transcriptional regulator
MDGJMAFB_00387 1.1e-183 ydeR EGP Major facilitator Superfamily
MDGJMAFB_00388 3.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
MDGJMAFB_00389 4.8e-69 ydeP K Transcriptional regulator
MDGJMAFB_00390 1.6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MDGJMAFB_00391 1.2e-57 K HxlR-like helix-turn-helix
MDGJMAFB_00392 9.5e-106 ydeN S Serine hydrolase
MDGJMAFB_00393 7.1e-74 maoC I N-terminal half of MaoC dehydratase
MDGJMAFB_00394 5.1e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDGJMAFB_00395 3.5e-152 ydeK EG -transporter
MDGJMAFB_00396 2.3e-85 K Transcriptional regulator C-terminal region
MDGJMAFB_00397 3.7e-15 ptsH G PTS HPr component phosphorylation site
MDGJMAFB_00398 1.1e-31 S SNARE associated Golgi protein
MDGJMAFB_00399 8.4e-103
MDGJMAFB_00400 3.9e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
MDGJMAFB_00401 4e-44 ydeH
MDGJMAFB_00402 2.1e-217 ydeG EGP Major facilitator superfamily
MDGJMAFB_00403 1.8e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDGJMAFB_00404 3.3e-13 ydeE K AraC family transcriptional regulator
MDGJMAFB_00405 8.2e-90 ydeE K AraC family transcriptional regulator
MDGJMAFB_00406 2.2e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MDGJMAFB_00407 6.9e-164 rhaS5 K AraC-like ligand binding domain
MDGJMAFB_00408 2.8e-141 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MDGJMAFB_00409 2.3e-78 carD K Transcription factor
MDGJMAFB_00410 8.7e-30 cspL K Cold shock
MDGJMAFB_00411 1.2e-111 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MDGJMAFB_00415 9.6e-11
MDGJMAFB_00416 3.5e-42 S Putative amidase domain
MDGJMAFB_00417 1.2e-135 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MDGJMAFB_00418 3.8e-45
MDGJMAFB_00419 2.2e-75 rimJ2 J Acetyltransferase (GNAT) domain
MDGJMAFB_00427 1.6e-84 ydcK S Belongs to the SprT family
MDGJMAFB_00428 0.0 yhgF K COG2183 Transcriptional accessory protein
MDGJMAFB_00429 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MDGJMAFB_00430 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDGJMAFB_00431 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MDGJMAFB_00432 2e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
MDGJMAFB_00433 7.1e-189 rsbU 3.1.3.3 KT phosphatase
MDGJMAFB_00434 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MDGJMAFB_00435 5.2e-57 rsbS T antagonist
MDGJMAFB_00436 1.3e-143 rsbR T Positive regulator of sigma-B
MDGJMAFB_00437 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MDGJMAFB_00438 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MDGJMAFB_00439 1.6e-221 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDGJMAFB_00440 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MDGJMAFB_00441 5.2e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDGJMAFB_00442 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MDGJMAFB_00443 3.9e-260 ydbT S Membrane
MDGJMAFB_00444 2.1e-82 ydbS S Bacterial PH domain
MDGJMAFB_00445 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDGJMAFB_00446 2.7e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDGJMAFB_00447 8.7e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MDGJMAFB_00448 1.5e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MDGJMAFB_00449 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDGJMAFB_00450 2.2e-07 S Fur-regulated basic protein A
MDGJMAFB_00451 1.1e-18 S Fur-regulated basic protein B
MDGJMAFB_00452 1.5e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MDGJMAFB_00453 2.7e-52 ydbL
MDGJMAFB_00454 1.2e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MDGJMAFB_00455 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
MDGJMAFB_00457 4.4e-181 ydbI S AI-2E family transporter
MDGJMAFB_00458 5.3e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDGJMAFB_00459 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
MDGJMAFB_00460 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MDGJMAFB_00461 3.9e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MDGJMAFB_00462 2.3e-153 ydbD P Catalase
MDGJMAFB_00463 6.9e-62 ydbC S Domain of unknown function (DUF4937
MDGJMAFB_00464 8.9e-59 ydbB G Cupin domain
MDGJMAFB_00466 5.5e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
MDGJMAFB_00467 1.1e-75 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
MDGJMAFB_00469 5e-224 mntH P H( )-stimulated, divalent metal cation uptake system
MDGJMAFB_00470 9.4e-40
MDGJMAFB_00472 1.8e-72 sdpB S Protein conserved in bacteria
MDGJMAFB_00473 1.8e-27
MDGJMAFB_00475 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MDGJMAFB_00476 6.6e-78 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MDGJMAFB_00477 0.0 ydaO E amino acid
MDGJMAFB_00478 0.0 ydaN S Bacterial cellulose synthase subunit
MDGJMAFB_00479 5e-232 ydaM M Glycosyl transferase family group 2
MDGJMAFB_00480 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MDGJMAFB_00481 2.5e-150 ydaK T Diguanylate cyclase, GGDEF domain
MDGJMAFB_00482 4.5e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
MDGJMAFB_00483 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDGJMAFB_00484 2.5e-74 lrpC K Transcriptional regulator
MDGJMAFB_00485 2.5e-46 ydzA EGP Major facilitator Superfamily
MDGJMAFB_00486 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MDGJMAFB_00487 6.8e-77 ydaG 1.4.3.5 S general stress protein
MDGJMAFB_00488 1e-101 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MDGJMAFB_00489 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
MDGJMAFB_00490 3.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDGJMAFB_00491 3.1e-99 ydaC Q Methyltransferase domain
MDGJMAFB_00492 1.3e-292 ydaB IQ acyl-CoA ligase
MDGJMAFB_00493 0.0 mtlR K transcriptional regulator, MtlR
MDGJMAFB_00494 3.2e-83 ydhF S Oxidoreductase
MDGJMAFB_00495 6.7e-77 ydhF S Oxidoreductase
MDGJMAFB_00496 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MDGJMAFB_00497 3.1e-49 yczJ S biosynthesis
MDGJMAFB_00499 1.3e-119 ycsK E anatomical structure formation involved in morphogenesis
MDGJMAFB_00500 1.2e-132 kipR K Transcriptional regulator
MDGJMAFB_00501 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MDGJMAFB_00502 4.7e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MDGJMAFB_00503 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
MDGJMAFB_00504 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MDGJMAFB_00505 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
MDGJMAFB_00506 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MDGJMAFB_00508 3.9e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MDGJMAFB_00509 9.1e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
MDGJMAFB_00510 3.2e-74 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MDGJMAFB_00511 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MDGJMAFB_00512 3.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MDGJMAFB_00513 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MDGJMAFB_00514 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MDGJMAFB_00515 3.4e-53
MDGJMAFB_00516 1.9e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
MDGJMAFB_00517 9.3e-308 ycnJ P protein, homolog of Cu resistance protein CopC
MDGJMAFB_00518 1.4e-99 ycnI S protein conserved in bacteria
MDGJMAFB_00519 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDGJMAFB_00520 6.1e-149 glcU U Glucose uptake
MDGJMAFB_00521 3.8e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDGJMAFB_00522 4.8e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDGJMAFB_00523 3.9e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDGJMAFB_00524 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
MDGJMAFB_00525 1.6e-45 ycnE S Monooxygenase
MDGJMAFB_00526 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
MDGJMAFB_00527 1.1e-153 ycnC K Transcriptional regulator
MDGJMAFB_00528 7e-251 ycnB EGP Major facilitator Superfamily
MDGJMAFB_00529 2.7e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MDGJMAFB_00530 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MDGJMAFB_00531 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDGJMAFB_00532 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDGJMAFB_00533 7.5e-242 lysC 2.7.2.4 E Belongs to the aspartokinase family
MDGJMAFB_00537 5.8e-78 S aspartate phosphatase
MDGJMAFB_00538 1.7e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MDGJMAFB_00539 2.3e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDGJMAFB_00540 1.1e-203 yclI V ABC transporter (permease) YclI
MDGJMAFB_00541 1.9e-121 yclH P ABC transporter
MDGJMAFB_00542 5.6e-195 gerKB F Spore germination protein
MDGJMAFB_00543 5.2e-226 gerKC S spore germination
MDGJMAFB_00544 1.5e-281 gerKA EG Spore germination protein
MDGJMAFB_00546 1.9e-298 yclG M Pectate lyase superfamily protein
MDGJMAFB_00547 4.7e-266 dtpT E amino acid peptide transporter
MDGJMAFB_00548 1.2e-157 yclE 3.4.11.5 S Alpha beta hydrolase
MDGJMAFB_00549 2.3e-81 yclD
MDGJMAFB_00550 4e-39 bsdD 4.1.1.61 S response to toxic substance
MDGJMAFB_00551 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MDGJMAFB_00552 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MDGJMAFB_00553 1.2e-160 bsdA K LysR substrate binding domain
MDGJMAFB_00554 6.4e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MDGJMAFB_00555 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
MDGJMAFB_00556 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MDGJMAFB_00557 9.7e-115 yczE S membrane
MDGJMAFB_00558 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MDGJMAFB_00559 1.6e-252 ycxD K GntR family transcriptional regulator
MDGJMAFB_00560 7.6e-161 ycxC EG EamA-like transporter family
MDGJMAFB_00561 3.1e-85 S YcxB-like protein
MDGJMAFB_00562 2.2e-224 EGP Major Facilitator Superfamily
MDGJMAFB_00563 5.7e-140 srfAD Q thioesterase
MDGJMAFB_00564 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
MDGJMAFB_00565 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDGJMAFB_00566 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDGJMAFB_00567 1.3e-63 hxlR K transcriptional
MDGJMAFB_00568 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MDGJMAFB_00569 3e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
MDGJMAFB_00570 1.9e-178 tlpC 2.7.13.3 NT chemotaxis protein
MDGJMAFB_00571 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
MDGJMAFB_00572 1.2e-67 nin S Competence protein J (ComJ)
MDGJMAFB_00573 1.2e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDGJMAFB_00574 7.8e-52 yckD S Protein of unknown function (DUF2680)
MDGJMAFB_00575 4e-75 yckC S membrane
MDGJMAFB_00576 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MDGJMAFB_00577 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
MDGJMAFB_00578 1.6e-227 yciC S GTPases (G3E family)
MDGJMAFB_00579 7.9e-108 yciB M ErfK YbiS YcfS YnhG
MDGJMAFB_00580 6.7e-170 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
MDGJMAFB_00581 1.7e-221 nasA P COG2223 Nitrate nitrite transporter
MDGJMAFB_00582 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
MDGJMAFB_00583 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDGJMAFB_00584 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MDGJMAFB_00585 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
MDGJMAFB_00586 3.2e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MDGJMAFB_00587 6.9e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MDGJMAFB_00588 6.1e-157 I alpha/beta hydrolase fold
MDGJMAFB_00589 6.5e-138 ycgR S permeases
MDGJMAFB_00590 2.6e-147 ycgQ S membrane
MDGJMAFB_00591 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
MDGJMAFB_00592 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDGJMAFB_00593 6.2e-293 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MDGJMAFB_00594 5.1e-170 ycgM E Proline dehydrogenase
MDGJMAFB_00595 2.9e-145 ycgL S Predicted nucleotidyltransferase
MDGJMAFB_00596 1.4e-181 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MDGJMAFB_00597 5.6e-175 oxyR3 K LysR substrate binding domain
MDGJMAFB_00598 9e-144 yafE Q ubiE/COQ5 methyltransferase family
MDGJMAFB_00599 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MDGJMAFB_00600 4.7e-108 tmrB S AAA domain
MDGJMAFB_00601 4.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDGJMAFB_00602 2.4e-112 ycgI S Domain of unknown function (DUF1989)
MDGJMAFB_00603 9e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MDGJMAFB_00604 9.2e-149 yqcI S YqcI/YcgG family
MDGJMAFB_00605 6.8e-113 ycgF E Lysine exporter protein LysE YggA
MDGJMAFB_00606 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
MDGJMAFB_00607 5.1e-263 mdr EGP Major facilitator Superfamily
MDGJMAFB_00608 3.9e-290 lctP C L-lactate permease
MDGJMAFB_00609 9.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDGJMAFB_00610 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
MDGJMAFB_00611 4.1e-81 ycgB
MDGJMAFB_00612 8.7e-257 ycgA S Membrane
MDGJMAFB_00613 2e-219 amhX S amidohydrolase
MDGJMAFB_00614 5.3e-164 opuAC E glycine betaine
MDGJMAFB_00615 1.3e-127 opuAB P glycine betaine
MDGJMAFB_00616 5.1e-229 proV 3.6.3.32 E glycine betaine
MDGJMAFB_00617 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
MDGJMAFB_00618 5e-202 yceJ EGP Uncharacterised MFS-type transporter YbfB
MDGJMAFB_00619 1.9e-217 naiP P Uncharacterised MFS-type transporter YbfB
MDGJMAFB_00620 2e-192 yceH P Belongs to the TelA family
MDGJMAFB_00621 0.0 yceG S Putative component of 'biosynthetic module'
MDGJMAFB_00622 1.4e-136 terC P Protein of unknown function (DUF475)
MDGJMAFB_00623 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
MDGJMAFB_00624 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
MDGJMAFB_00625 2.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
MDGJMAFB_00626 7.7e-188 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDGJMAFB_00627 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MDGJMAFB_00628 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MDGJMAFB_00629 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
MDGJMAFB_00630 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
MDGJMAFB_00631 1.2e-138 IQ Enoyl-(Acyl carrier protein) reductase
MDGJMAFB_00632 1.2e-173 S response regulator aspartate phosphatase
MDGJMAFB_00633 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
MDGJMAFB_00634 5.5e-262 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
MDGJMAFB_00635 7e-275 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
MDGJMAFB_00636 1.9e-176 ycdA S Domain of unknown function (DUF5105)
MDGJMAFB_00637 5e-173 yccK C Aldo keto reductase
MDGJMAFB_00638 2.2e-202 natB CP ABC-2 family transporter protein
MDGJMAFB_00639 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
MDGJMAFB_00640 1.2e-126 lytR_2 T LytTr DNA-binding domain
MDGJMAFB_00641 2.4e-154 2.7.13.3 T GHKL domain
MDGJMAFB_00642 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
MDGJMAFB_00643 7.1e-57 S RDD family
MDGJMAFB_00644 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MDGJMAFB_00645 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MDGJMAFB_00646 6.3e-102 yxaF K Transcriptional regulator
MDGJMAFB_00647 3e-225 lmrB EGP the major facilitator superfamily
MDGJMAFB_00648 8.6e-204 ycbU E Selenocysteine lyase
MDGJMAFB_00649 5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDGJMAFB_00650 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MDGJMAFB_00651 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MDGJMAFB_00652 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
MDGJMAFB_00653 6.6e-136 ycbR T vWA found in TerF C terminus
MDGJMAFB_00654 1.3e-78 sleB 3.5.1.28 M Cell wall
MDGJMAFB_00655 8.2e-53 ycbP S Protein of unknown function (DUF2512)
MDGJMAFB_00656 5.1e-114 S ABC-2 family transporter protein
MDGJMAFB_00657 4.8e-168 ycbN V ABC transporter, ATP-binding protein
MDGJMAFB_00658 4.4e-169 T PhoQ Sensor
MDGJMAFB_00659 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDGJMAFB_00660 8.4e-168 eamA1 EG spore germination
MDGJMAFB_00661 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
MDGJMAFB_00662 1.6e-171 ycbJ S Macrolide 2'-phosphotransferase
MDGJMAFB_00663 2.9e-295 garD 4.2.1.42, 4.2.1.7 G Altronate
MDGJMAFB_00664 2.1e-123 ycbG K FCD
MDGJMAFB_00665 1.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MDGJMAFB_00666 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
MDGJMAFB_00667 4.5e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDGJMAFB_00668 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
MDGJMAFB_00669 2.6e-169 glnL T Regulator
MDGJMAFB_00670 4.7e-228 phoQ 2.7.13.3 T Histidine kinase
MDGJMAFB_00671 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
MDGJMAFB_00672 2.8e-255 agcS E Sodium alanine symporter
MDGJMAFB_00673 2.3e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
MDGJMAFB_00674 1.1e-259 mmuP E amino acid
MDGJMAFB_00675 1e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MDGJMAFB_00677 4.9e-128 K UTRA
MDGJMAFB_00678 3e-136 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDGJMAFB_00679 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDGJMAFB_00680 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDGJMAFB_00681 3.9e-192 yceA S Belongs to the UPF0176 family
MDGJMAFB_00682 6.7e-167 ybfP K Transcriptional regulator
MDGJMAFB_00683 1.2e-252 S Erythromycin esterase
MDGJMAFB_00684 3e-44 ybfN
MDGJMAFB_00685 4.8e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MDGJMAFB_00686 2.7e-85 ybfM S SNARE associated Golgi protein
MDGJMAFB_00687 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDGJMAFB_00688 1e-167 S Alpha/beta hydrolase family
MDGJMAFB_00690 1.5e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
MDGJMAFB_00691 5.2e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MDGJMAFB_00692 2e-144 msmR K AraC-like ligand binding domain
MDGJMAFB_00693 1.4e-159 ybfH EG EamA-like transporter family
MDGJMAFB_00694 0.0 ybfG M Domain of unknown function (DUF1906)
MDGJMAFB_00696 4.6e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
MDGJMAFB_00697 3e-170 ybfA 3.4.15.5 K FR47-like protein
MDGJMAFB_00698 1.5e-34 S Protein of unknown function (DUF2651)
MDGJMAFB_00699 7.3e-258 glpT G -transporter
MDGJMAFB_00700 1.3e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MDGJMAFB_00701 1.8e-290 ybeC E amino acid
MDGJMAFB_00702 4.9e-41 ybyB
MDGJMAFB_00703 5.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MDGJMAFB_00704 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
MDGJMAFB_00705 4.9e-30 ybxH S Family of unknown function (DUF5370)
MDGJMAFB_00706 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
MDGJMAFB_00707 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MDGJMAFB_00708 9.8e-214 ybdO S Domain of unknown function (DUF4885)
MDGJMAFB_00709 1.7e-151 ybdN
MDGJMAFB_00710 8.8e-139 KLT Protein tyrosine kinase
MDGJMAFB_00712 7.2e-170 T His Kinase A (phospho-acceptor) domain
MDGJMAFB_00713 1.5e-123 T Transcriptional regulatory protein, C terminal
MDGJMAFB_00714 2.6e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MDGJMAFB_00715 1.2e-55
MDGJMAFB_00716 7.7e-203 ybcL EGP Major facilitator Superfamily
MDGJMAFB_00717 5.1e-50 ybzH K Helix-turn-helix domain
MDGJMAFB_00718 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
MDGJMAFB_00719 3.9e-47
MDGJMAFB_00720 1.3e-93 can 4.2.1.1 P carbonic anhydrase
MDGJMAFB_00721 0.0 ybcC S Belongs to the UPF0753 family
MDGJMAFB_00722 3.5e-272 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MDGJMAFB_00723 9.6e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDGJMAFB_00724 4.9e-119 adaA 3.2.2.21 K Transcriptional regulator
MDGJMAFB_00725 1.8e-170 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MDGJMAFB_00726 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDGJMAFB_00727 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDGJMAFB_00728 1.5e-224 ybbR S protein conserved in bacteria
MDGJMAFB_00729 7.9e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDGJMAFB_00730 4.1e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MDGJMAFB_00731 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MDGJMAFB_00737 2.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
MDGJMAFB_00738 1.9e-86 ybbJ J acetyltransferase
MDGJMAFB_00739 1e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MDGJMAFB_00740 2.5e-150 ybbH K transcriptional
MDGJMAFB_00741 1.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDGJMAFB_00742 2.4e-225 yfeW 3.4.16.4 V Belongs to the UPF0214 family
MDGJMAFB_00743 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MDGJMAFB_00744 1e-237 ybbC 3.2.1.52 S protein conserved in bacteria
MDGJMAFB_00745 1e-303 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
MDGJMAFB_00746 4.5e-153 feuA P Iron-uptake system-binding protein
MDGJMAFB_00747 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDGJMAFB_00748 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDGJMAFB_00749 1.4e-141 ybbA S Putative esterase
MDGJMAFB_00750 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
MDGJMAFB_00752 1.5e-245 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
MDGJMAFB_00753 3.4e-39 S COG NOG14552 non supervised orthologous group
MDGJMAFB_00754 3.4e-39 S COG NOG14552 non supervised orthologous group
MDGJMAFB_00758 2e-08
MDGJMAFB_00759 7.1e-59
MDGJMAFB_00760 5.7e-25
MDGJMAFB_00761 6.6e-187 A Pre-toxin TG
MDGJMAFB_00762 9.1e-41
MDGJMAFB_00763 1e-15
MDGJMAFB_00764 4.4e-18 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MDGJMAFB_00766 4.1e-29
MDGJMAFB_00768 9e-17
MDGJMAFB_00769 2.4e-123 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MDGJMAFB_00770 2.2e-56 K DNA binding
MDGJMAFB_00773 3.6e-27
MDGJMAFB_00775 3.8e-36 L Phage integrase, N-terminal SAM-like domain
MDGJMAFB_00778 3.4e-39 S COG NOG14552 non supervised orthologous group
MDGJMAFB_00779 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
MDGJMAFB_00780 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MDGJMAFB_00781 1.2e-84 gerD
MDGJMAFB_00782 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MDGJMAFB_00783 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MDGJMAFB_00784 9.7e-66 ybaK S Protein of unknown function (DUF2521)
MDGJMAFB_00785 2.4e-144 ybaJ Q Methyltransferase domain
MDGJMAFB_00786 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MDGJMAFB_00787 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDGJMAFB_00788 9.1e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDGJMAFB_00789 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDGJMAFB_00790 1.9e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDGJMAFB_00791 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDGJMAFB_00792 3.6e-58 rplQ J Ribosomal protein L17
MDGJMAFB_00793 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDGJMAFB_00794 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDGJMAFB_00795 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDGJMAFB_00796 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MDGJMAFB_00797 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDGJMAFB_00798 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
MDGJMAFB_00799 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDGJMAFB_00800 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDGJMAFB_00801 1.8e-72 rplO J binds to the 23S rRNA
MDGJMAFB_00802 1.9e-23 rpmD J Ribosomal protein L30
MDGJMAFB_00803 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDGJMAFB_00804 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDGJMAFB_00805 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDGJMAFB_00806 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDGJMAFB_00807 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDGJMAFB_00808 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDGJMAFB_00809 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDGJMAFB_00810 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDGJMAFB_00811 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDGJMAFB_00812 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MDGJMAFB_00813 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDGJMAFB_00814 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDGJMAFB_00815 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDGJMAFB_00816 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDGJMAFB_00817 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDGJMAFB_00818 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDGJMAFB_00819 3e-105 rplD J Forms part of the polypeptide exit tunnel
MDGJMAFB_00820 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDGJMAFB_00821 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MDGJMAFB_00822 4e-181 ybaC 3.4.11.5 S Alpha/beta hydrolase family
MDGJMAFB_00823 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDGJMAFB_00824 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDGJMAFB_00825 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDGJMAFB_00826 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDGJMAFB_00827 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
MDGJMAFB_00828 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDGJMAFB_00829 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDGJMAFB_00830 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
MDGJMAFB_00831 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDGJMAFB_00832 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDGJMAFB_00833 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDGJMAFB_00834 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDGJMAFB_00835 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
MDGJMAFB_00836 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDGJMAFB_00837 4.4e-115 sigH K Belongs to the sigma-70 factor family
MDGJMAFB_00838 1.2e-88 yacP S RNA-binding protein containing a PIN domain
MDGJMAFB_00839 1.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDGJMAFB_00840 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDGJMAFB_00841 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDGJMAFB_00842 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
MDGJMAFB_00843 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDGJMAFB_00844 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MDGJMAFB_00845 6.5e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MDGJMAFB_00846 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MDGJMAFB_00847 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MDGJMAFB_00848 2.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDGJMAFB_00849 0.0 clpC O Belongs to the ClpA ClpB family
MDGJMAFB_00850 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MDGJMAFB_00851 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MDGJMAFB_00852 2.9e-76 ctsR K Belongs to the CtsR family
MDGJMAFB_00853 3.4e-39 S COG NOG14552 non supervised orthologous group
MDGJMAFB_00858 2e-08
MDGJMAFB_00863 3.4e-39 S COG NOG14552 non supervised orthologous group
MDGJMAFB_00864 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MDGJMAFB_00865 4.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDGJMAFB_00866 4.1e-30 yazB K transcriptional
MDGJMAFB_00867 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MDGJMAFB_00868 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MDGJMAFB_00869 8.5e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MDGJMAFB_00870 2.3e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
MDGJMAFB_00871 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MDGJMAFB_00872 6.3e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MDGJMAFB_00873 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MDGJMAFB_00874 3.4e-152 yacD 5.2.1.8 O peptidyl-prolyl isomerase
MDGJMAFB_00875 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDGJMAFB_00876 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MDGJMAFB_00877 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDGJMAFB_00878 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MDGJMAFB_00879 2.9e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDGJMAFB_00880 5.7e-186 KLT serine threonine protein kinase
MDGJMAFB_00881 2.6e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
MDGJMAFB_00882 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MDGJMAFB_00885 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MDGJMAFB_00886 1.1e-44 divIC D Septum formation initiator
MDGJMAFB_00887 3.9e-108 yabQ S spore cortex biosynthesis protein
MDGJMAFB_00888 1.5e-49 yabP S Sporulation protein YabP
MDGJMAFB_00889 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MDGJMAFB_00890 8.6e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MDGJMAFB_00891 3.8e-285 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDGJMAFB_00892 1.5e-92 spoVT K stage V sporulation protein
MDGJMAFB_00893 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDGJMAFB_00894 2.4e-39 yabK S Peptide ABC transporter permease
MDGJMAFB_00895 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDGJMAFB_00896 1.1e-88 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MDGJMAFB_00897 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDGJMAFB_00898 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDGJMAFB_00899 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MDGJMAFB_00900 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MDGJMAFB_00901 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MDGJMAFB_00902 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MDGJMAFB_00903 7.8e-39 veg S protein conserved in bacteria
MDGJMAFB_00904 1.6e-136 yabG S peptidase
MDGJMAFB_00905 2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDGJMAFB_00906 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDGJMAFB_00907 4.5e-167 rpfB GH23 T protein conserved in bacteria
MDGJMAFB_00908 1.2e-143 tatD L hydrolase, TatD
MDGJMAFB_00909 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDGJMAFB_00910 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
MDGJMAFB_00911 3.5e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDGJMAFB_00912 1.5e-49 yazA L endonuclease containing a URI domain
MDGJMAFB_00913 2.7e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
MDGJMAFB_00914 4.8e-31 yabA L Involved in initiation control of chromosome replication
MDGJMAFB_00915 1.8e-145 yaaT S stage 0 sporulation protein
MDGJMAFB_00916 1.1e-181 holB 2.7.7.7 L DNA polymerase III
MDGJMAFB_00917 1.5e-71 yaaR S protein conserved in bacteria
MDGJMAFB_00918 2.2e-54 yaaQ S protein conserved in bacteria
MDGJMAFB_00919 6.9e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDGJMAFB_00920 1.3e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MDGJMAFB_00921 1.4e-201 yaaN P Belongs to the TelA family
MDGJMAFB_00922 9.9e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MDGJMAFB_00923 3.4e-31 csfB S Inhibitor of sigma-G Gin
MDGJMAFB_00926 3.4e-39 S COG NOG14552 non supervised orthologous group
MDGJMAFB_00927 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
MDGJMAFB_00928 7.9e-32 yaaL S Protein of unknown function (DUF2508)
MDGJMAFB_00929 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDGJMAFB_00930 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MDGJMAFB_00931 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDGJMAFB_00932 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDGJMAFB_00933 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
MDGJMAFB_00934 1.2e-212 yaaH M Glycoside Hydrolase Family
MDGJMAFB_00935 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MDGJMAFB_00936 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MDGJMAFB_00937 1.3e-09
MDGJMAFB_00938 1.2e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDGJMAFB_00939 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MDGJMAFB_00940 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MDGJMAFB_00941 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MDGJMAFB_00942 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MDGJMAFB_00943 1e-181 yaaC S YaaC-like Protein
MDGJMAFB_00946 3.4e-39 S COG NOG14552 non supervised orthologous group
MDGJMAFB_00947 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDGJMAFB_00948 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDGJMAFB_00949 1.8e-37 yaaB S Domain of unknown function (DUF370)
MDGJMAFB_00950 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDGJMAFB_00951 2.4e-33 yaaA S S4 domain
MDGJMAFB_00952 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDGJMAFB_00953 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDGJMAFB_00954 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDGJMAFB_00955 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDGJMAFB_00956 6.5e-108 jag S single-stranded nucleic acid binding R3H
MDGJMAFB_00957 1.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDGJMAFB_00958 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDGJMAFB_00959 4.1e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MDGJMAFB_00960 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MDGJMAFB_00961 2.5e-74 S Bacterial PH domain
MDGJMAFB_00962 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
MDGJMAFB_00963 1.3e-148 spo0J K Belongs to the ParB family
MDGJMAFB_00964 1.6e-111 yyaC S Sporulation protein YyaC
MDGJMAFB_00965 8.1e-177 yyaD S Membrane
MDGJMAFB_00966 2.3e-33 yyzM S protein conserved in bacteria
MDGJMAFB_00967 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDGJMAFB_00968 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDGJMAFB_00969 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
MDGJMAFB_00970 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDGJMAFB_00971 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDGJMAFB_00972 1.7e-142 xth 3.1.11.2 L exodeoxyribonuclease III
MDGJMAFB_00973 2.2e-176 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
MDGJMAFB_00974 4.9e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDGJMAFB_00975 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
MDGJMAFB_00976 6.1e-244 EGP Major facilitator superfamily
MDGJMAFB_00977 8e-168 yyaK S CAAX protease self-immunity
MDGJMAFB_00978 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MDGJMAFB_00979 5.7e-24 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MDGJMAFB_00980 3.4e-67 yrhP E LysE type translocator
MDGJMAFB_00981 3.5e-184 C NADH:flavin oxidoreductase / NADH oxidase family
MDGJMAFB_00982 7.6e-63 K Tetracycline repressor, C-terminal all-alpha domain
MDGJMAFB_00983 4.2e-111 I COG0657 Esterase lipase
MDGJMAFB_00984 6.5e-30 K HxlR-like helix-turn-helix
MDGJMAFB_00985 9.4e-40 S Ester cyclase
MDGJMAFB_00986 7.7e-31 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MDGJMAFB_00987 6.6e-246 tetL EGP Major facilitator Superfamily
MDGJMAFB_00988 2e-103 yyaP 1.5.1.3 H RibD C-terminal domain
MDGJMAFB_00989 3.5e-66 yyaQ S YjbR
MDGJMAFB_00990 5.3e-95 yyaR K Acetyltransferase (GNAT) domain
MDGJMAFB_00991 5.5e-96 yyaS S Membrane
MDGJMAFB_00992 7.6e-71 yjcF S Acetyltransferase (GNAT) domain
MDGJMAFB_00993 5.6e-77 yybA 2.3.1.57 K transcriptional
MDGJMAFB_00994 2.4e-124 S Metallo-beta-lactamase superfamily
MDGJMAFB_00995 6.2e-74 yybC
MDGJMAFB_00996 2.9e-77 yjcF S Acetyltransferase (GNAT) domain
MDGJMAFB_00997 1.1e-164 yybE K Transcriptional regulator
MDGJMAFB_00998 1.3e-216 ynfM EGP Major facilitator Superfamily
MDGJMAFB_00999 4e-121 yybG S Pentapeptide repeat-containing protein
MDGJMAFB_01000 1.7e-66 yybH S SnoaL-like domain
MDGJMAFB_01001 5.4e-121
MDGJMAFB_01002 1.3e-110 K TipAS antibiotic-recognition domain
MDGJMAFB_01003 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
MDGJMAFB_01005 7.3e-61
MDGJMAFB_01006 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MDGJMAFB_01007 7.5e-67 ydeP3 K Transcriptional regulator
MDGJMAFB_01008 3.3e-83 cotF M Spore coat protein
MDGJMAFB_01010 8.3e-160 yybS S membrane
MDGJMAFB_01011 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MDGJMAFB_01012 6.4e-73 rplI J binds to the 23S rRNA
MDGJMAFB_01013 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MDGJMAFB_01014 1.4e-220 yeaN P COG2807 Cyanate permease
MDGJMAFB_01015 1.9e-15 yycC K YycC-like protein
MDGJMAFB_01017 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
MDGJMAFB_01018 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MDGJMAFB_01019 3.7e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDGJMAFB_01020 6.6e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDGJMAFB_01025 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDGJMAFB_01026 0.0 vicK 2.7.13.3 T Histidine kinase
MDGJMAFB_01027 3.1e-259 yycH S protein conserved in bacteria
MDGJMAFB_01028 1.1e-153 yycI S protein conserved in bacteria
MDGJMAFB_01029 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MDGJMAFB_01030 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDGJMAFB_01031 1.4e-33 S Peptidase propeptide and YPEB domain
MDGJMAFB_01032 2.6e-73 S Peptidase propeptide and YPEB domain
MDGJMAFB_01033 3.4e-94 K PFAM response regulator receiver
MDGJMAFB_01034 1.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
MDGJMAFB_01035 5.8e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MDGJMAFB_01036 7.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MDGJMAFB_01037 1.3e-260 rocE E amino acid
MDGJMAFB_01038 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MDGJMAFB_01040 8.5e-188 S aspartate phosphatase
MDGJMAFB_01041 4.5e-85 yycN 2.3.1.128 K Acetyltransferase
MDGJMAFB_01042 2.2e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MDGJMAFB_01043 2.3e-207 yycP
MDGJMAFB_01044 5.7e-31 yycQ S Protein of unknown function (DUF2651)
MDGJMAFB_01046 1.1e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MDGJMAFB_01047 2e-60
MDGJMAFB_01048 1.1e-09 S YyzF-like protein
MDGJMAFB_01049 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDGJMAFB_01050 2.2e-280 L AAA ATPase domain
MDGJMAFB_01051 3.2e-182 3.6.4.12 L AAA domain
MDGJMAFB_01052 1.5e-91
MDGJMAFB_01053 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
MDGJMAFB_01054 2.3e-11
MDGJMAFB_01055 1.7e-184 S Radical SAM superfamily
MDGJMAFB_01056 1.4e-133 yydH O Peptidase M50
MDGJMAFB_01057 5.4e-110 prrC P ABC transporter
MDGJMAFB_01058 3.3e-119 S ABC-2 family transporter protein
MDGJMAFB_01059 7.1e-11
MDGJMAFB_01060 1.1e-124 yydK K Transcriptional regulator
MDGJMAFB_01061 1.1e-18 bglF G phosphotransferase system
MDGJMAFB_01062 4.1e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDGJMAFB_01063 3.8e-287 ahpF O Alkyl hydroperoxide reductase
MDGJMAFB_01064 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MDGJMAFB_01065 5.5e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDGJMAFB_01066 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
MDGJMAFB_01067 3.9e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MDGJMAFB_01068 7.3e-127 gntR K transcriptional
MDGJMAFB_01069 8e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MDGJMAFB_01070 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
MDGJMAFB_01071 1.3e-117 yxaC M effector of murein hydrolase
MDGJMAFB_01072 5.2e-50 S LrgA family
MDGJMAFB_01073 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
MDGJMAFB_01074 6.1e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MDGJMAFB_01075 2.1e-100 yxaF K Transcriptional regulator
MDGJMAFB_01076 8.7e-195 yxaG 1.13.11.24 S AraC-like ligand binding domain
MDGJMAFB_01077 4.5e-222 P Protein of unknown function (DUF418)
MDGJMAFB_01078 6.9e-75 yxaI S membrane protein domain
MDGJMAFB_01079 5.1e-64 S Family of unknown function (DUF5391)
MDGJMAFB_01080 9.9e-92 S PQQ-like domain
MDGJMAFB_01081 7.6e-214 yxaM U MFS_1 like family
MDGJMAFB_01082 0.0 asnB 6.3.5.4 E Asparagine synthase
MDGJMAFB_01083 1.1e-86 yxnB
MDGJMAFB_01084 1.9e-43 S Coenzyme PQQ synthesis protein D (PqqD)
MDGJMAFB_01085 2.8e-126 yxbB Q Met-10+ like-protein
MDGJMAFB_01086 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
MDGJMAFB_01087 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
MDGJMAFB_01088 1.7e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MDGJMAFB_01089 1.2e-208 yxbF K Bacterial regulatory proteins, tetR family
MDGJMAFB_01090 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
MDGJMAFB_01092 0.0 htpG O Molecular chaperone. Has ATPase activity
MDGJMAFB_01093 2.1e-244 csbC EGP Major facilitator Superfamily
MDGJMAFB_01094 8.3e-48 yxcD S Protein of unknown function (DUF2653)
MDGJMAFB_01096 4.1e-175 iolS C Aldo keto reductase
MDGJMAFB_01097 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
MDGJMAFB_01098 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDGJMAFB_01099 1.3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MDGJMAFB_01100 2.7e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MDGJMAFB_01101 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MDGJMAFB_01102 2.3e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MDGJMAFB_01103 4.7e-233 iolF EGP Major facilitator Superfamily
MDGJMAFB_01104 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MDGJMAFB_01105 8.6e-167 iolH G Xylose isomerase-like TIM barrel
MDGJMAFB_01106 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MDGJMAFB_01107 6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MDGJMAFB_01108 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDGJMAFB_01109 1.3e-179 T PhoQ Sensor
MDGJMAFB_01110 3.6e-140 yxdL V ABC transporter, ATP-binding protein
MDGJMAFB_01111 0.0 yxdM V ABC transporter (permease)
MDGJMAFB_01112 5.9e-58 yxeA S Protein of unknown function (DUF1093)
MDGJMAFB_01113 3.3e-175 fhuD P ABC transporter
MDGJMAFB_01114 1.4e-68
MDGJMAFB_01115 7.4e-16 yxeD
MDGJMAFB_01116 1.3e-20 yxeE
MDGJMAFB_01119 6.2e-151 yidA S hydrolases of the HAD superfamily
MDGJMAFB_01120 9.7e-183 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MDGJMAFB_01121 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDGJMAFB_01122 7.5e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDGJMAFB_01123 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
MDGJMAFB_01124 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
MDGJMAFB_01125 5.9e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
MDGJMAFB_01126 4e-212 yxeP 3.5.1.47 E hydrolase activity
MDGJMAFB_01127 4.3e-250 yxeQ S MmgE/PrpD family
MDGJMAFB_01128 3.3e-195 eutH E Ethanolamine utilisation protein, EutH
MDGJMAFB_01129 2.2e-151 yxxB S Domain of Unknown Function (DUF1206)
MDGJMAFB_01130 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MDGJMAFB_01131 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MDGJMAFB_01132 8.3e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MDGJMAFB_01133 7.9e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MDGJMAFB_01134 3.4e-250 lysP E amino acid
MDGJMAFB_01135 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MDGJMAFB_01136 5.9e-233 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
MDGJMAFB_01137 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MDGJMAFB_01138 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
MDGJMAFB_01139 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MDGJMAFB_01140 1.3e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MDGJMAFB_01141 4.3e-19 S Domain of unknown function (DUF5082)
MDGJMAFB_01142 1.2e-37 yxiC S Family of unknown function (DUF5344)
MDGJMAFB_01143 2.6e-217 S nuclease activity
MDGJMAFB_01144 9.4e-53
MDGJMAFB_01146 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDGJMAFB_01147 6.9e-278 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDGJMAFB_01148 2e-71 yxiE T Belongs to the universal stress protein A family
MDGJMAFB_01149 5.5e-34 S Sporulation delaying protein SdpA
MDGJMAFB_01150 8e-89
MDGJMAFB_01151 7.2e-13
MDGJMAFB_01152 3.6e-62 K helix_turn_helix, mercury resistance
MDGJMAFB_01153 1.6e-163 yxxF EG EamA-like transporter family
MDGJMAFB_01154 2.9e-38
MDGJMAFB_01155 2.8e-67 yxiG
MDGJMAFB_01156 1.5e-136
MDGJMAFB_01157 1.1e-42 yxiI S Protein of unknown function (DUF2716)
MDGJMAFB_01158 1.2e-34
MDGJMAFB_01161 8.3e-45 yxiJ S YxiJ-like protein
MDGJMAFB_01164 1.4e-60 S Protein of unknown function (DUF2812)
MDGJMAFB_01165 6.6e-54 padR K Transcriptional regulator PadR-like family
MDGJMAFB_01166 1.5e-214 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
MDGJMAFB_01167 1.1e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MDGJMAFB_01168 5.6e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
MDGJMAFB_01169 3.4e-110
MDGJMAFB_01170 4.1e-150 licT K transcriptional antiterminator
MDGJMAFB_01171 2.8e-142 exoK GH16 M licheninase activity
MDGJMAFB_01172 6.6e-224 citH C Citrate transporter
MDGJMAFB_01173 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
MDGJMAFB_01174 2.7e-48 yxiS
MDGJMAFB_01175 1.2e-104 T Domain of unknown function (DUF4163)
MDGJMAFB_01176 1.2e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MDGJMAFB_01177 2.7e-157 rlmA 2.1.1.187 Q Methyltransferase domain
MDGJMAFB_01178 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
MDGJMAFB_01179 2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MDGJMAFB_01180 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MDGJMAFB_01181 1.8e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MDGJMAFB_01182 5.1e-220 yxjG 2.1.1.14 E Methionine synthase
MDGJMAFB_01183 1.9e-219 yxjG 2.1.1.14 E Methionine synthase
MDGJMAFB_01184 1.8e-84 yxjI S LURP-one-related
MDGJMAFB_01186 8.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MDGJMAFB_01187 3.2e-113 K helix_turn_helix, Lux Regulon
MDGJMAFB_01188 8e-187 yxjM T Signal transduction histidine kinase
MDGJMAFB_01189 1.3e-76 S Protein of unknown function (DUF1453)
MDGJMAFB_01190 3.9e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MDGJMAFB_01191 1.7e-74 yxkC S Domain of unknown function (DUF4352)
MDGJMAFB_01192 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDGJMAFB_01193 5.1e-273 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDGJMAFB_01194 7.7e-163 lrp QT PucR C-terminal helix-turn-helix domain
MDGJMAFB_01195 5.9e-205 msmK P Belongs to the ABC transporter superfamily
MDGJMAFB_01196 1.1e-153 yxkH G Polysaccharide deacetylase
MDGJMAFB_01198 0.0 3.4.24.84 O Peptidase family M48
MDGJMAFB_01199 1.5e-229 cimH C COG3493 Na citrate symporter
MDGJMAFB_01200 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
MDGJMAFB_01201 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MDGJMAFB_01202 9.4e-311 cydD V ATP-binding
MDGJMAFB_01203 0.0 cydD V ATP-binding protein
MDGJMAFB_01204 1.7e-159 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDGJMAFB_01205 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
MDGJMAFB_01206 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
MDGJMAFB_01207 3.9e-48 yxlC S Family of unknown function (DUF5345)
MDGJMAFB_01208 1.2e-31
MDGJMAFB_01209 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
MDGJMAFB_01210 4.8e-165 yxlF V ABC transporter, ATP-binding protein
MDGJMAFB_01211 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MDGJMAFB_01212 4.8e-216 yxlH EGP Major facilitator Superfamily
MDGJMAFB_01213 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MDGJMAFB_01214 5e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MDGJMAFB_01215 1.1e-19 yxzF
MDGJMAFB_01216 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
MDGJMAFB_01217 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
MDGJMAFB_01218 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDGJMAFB_01219 7.3e-50 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MDGJMAFB_01220 2.4e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MDGJMAFB_01221 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MDGJMAFB_01222 2.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
MDGJMAFB_01223 2.5e-230 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDGJMAFB_01224 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDGJMAFB_01225 1.2e-232 dltB M membrane protein involved in D-alanine export
MDGJMAFB_01226 2.8e-290 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDGJMAFB_01227 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MDGJMAFB_01228 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
MDGJMAFB_01229 4e-130 ynfM EGP Major facilitator Superfamily
MDGJMAFB_01230 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
MDGJMAFB_01231 1.4e-92 K Helix-turn-helix XRE-family like proteins
MDGJMAFB_01232 1.1e-248 ywaD 3.4.11.10, 3.4.11.6 S PA domain
MDGJMAFB_01233 1.4e-231 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDGJMAFB_01234 6.8e-87 ywaE K Transcriptional regulator
MDGJMAFB_01235 3.7e-123 ywaF S Integral membrane protein
MDGJMAFB_01236 4.5e-168 gspA M General stress
MDGJMAFB_01237 1.2e-152 sacY K transcriptional antiterminator
MDGJMAFB_01238 2e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDGJMAFB_01239 2e-272 epr 3.4.21.62 O Belongs to the peptidase S8 family
MDGJMAFB_01240 1.1e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDGJMAFB_01241 4.9e-66 ywbC 4.4.1.5 E glyoxalase
MDGJMAFB_01242 5.4e-220 ywbD 2.1.1.191 J Methyltransferase
MDGJMAFB_01243 3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
MDGJMAFB_01244 1.1e-207 ywbF EGP Major facilitator Superfamily
MDGJMAFB_01245 2.3e-111 ywbG M effector of murein hydrolase
MDGJMAFB_01246 3.7e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MDGJMAFB_01247 4.3e-153 ywbI K Transcriptional regulator
MDGJMAFB_01248 6.9e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MDGJMAFB_01249 6.5e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MDGJMAFB_01250 4.2e-251 P COG0672 High-affinity Fe2 Pb2 permease
MDGJMAFB_01251 1e-183 ycdO P periplasmic lipoprotein involved in iron transport
MDGJMAFB_01252 4.9e-224 ywbN P Dyp-type peroxidase family protein
MDGJMAFB_01253 9e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MDGJMAFB_01254 9e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDGJMAFB_01255 9.8e-49 ywcB S Protein of unknown function, DUF485
MDGJMAFB_01257 2.2e-122 ywcC K transcriptional regulator
MDGJMAFB_01258 9.5e-60 gtcA S GtrA-like protein
MDGJMAFB_01259 5.3e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDGJMAFB_01260 3.1e-300 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MDGJMAFB_01261 1e-35 ywzA S membrane
MDGJMAFB_01262 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MDGJMAFB_01263 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MDGJMAFB_01264 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MDGJMAFB_01265 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MDGJMAFB_01266 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
MDGJMAFB_01267 8.6e-202 rodA D Belongs to the SEDS family
MDGJMAFB_01268 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MDGJMAFB_01269 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDGJMAFB_01270 0.0 vpr O Belongs to the peptidase S8 family
MDGJMAFB_01272 7e-150 sacT K transcriptional antiterminator
MDGJMAFB_01273 1.1e-138 focA P Formate/nitrite transporter
MDGJMAFB_01274 7.6e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDGJMAFB_01275 8.6e-289 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
MDGJMAFB_01276 2e-28 ywdA
MDGJMAFB_01277 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MDGJMAFB_01278 2.8e-57 pex K Transcriptional regulator PadR-like family
MDGJMAFB_01279 4e-113 ywdD
MDGJMAFB_01281 4.7e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
MDGJMAFB_01282 1.6e-115 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDGJMAFB_01283 1.7e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MDGJMAFB_01284 7.7e-49 ywdI S Family of unknown function (DUF5327)
MDGJMAFB_01285 3.7e-238 ywdJ F Xanthine uracil
MDGJMAFB_01286 4.3e-59 ywdK S small membrane protein
MDGJMAFB_01287 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MDGJMAFB_01288 1.8e-144 spsA M Spore Coat
MDGJMAFB_01289 2.6e-266 spsB M Capsule polysaccharide biosynthesis protein
MDGJMAFB_01290 3.5e-224 spsC E Belongs to the DegT DnrJ EryC1 family
MDGJMAFB_01291 1.2e-163 spsD 2.3.1.210 K Spore Coat
MDGJMAFB_01292 3.5e-213 spsE 2.5.1.56 M acid synthase
MDGJMAFB_01293 2.4e-130 spsF M Spore Coat
MDGJMAFB_01294 5.7e-186 spsG M Spore Coat
MDGJMAFB_01295 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MDGJMAFB_01296 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MDGJMAFB_01297 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MDGJMAFB_01298 1.3e-86 spsL 5.1.3.13 M Spore Coat
MDGJMAFB_01299 1.2e-77
MDGJMAFB_01300 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MDGJMAFB_01301 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MDGJMAFB_01302 0.0 rocB E arginine degradation protein
MDGJMAFB_01303 2.8e-249 lysP E amino acid
MDGJMAFB_01304 4.6e-206 ywfA EGP Major facilitator Superfamily
MDGJMAFB_01305 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MDGJMAFB_01306 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MDGJMAFB_01307 1.9e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDGJMAFB_01308 6.1e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MDGJMAFB_01309 1.9e-209 bacE EGP Major facilitator Superfamily
MDGJMAFB_01310 2.8e-232 ywfG 2.6.1.83 E Aminotransferase class I and II
MDGJMAFB_01311 2.2e-137 IQ Enoyl-(Acyl carrier protein) reductase
MDGJMAFB_01312 4.3e-146 ywfI C May function as heme-dependent peroxidase
MDGJMAFB_01313 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MDGJMAFB_01314 1.1e-156 cysL K Transcriptional regulator
MDGJMAFB_01315 1.3e-154 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MDGJMAFB_01316 9.8e-158 ywfM EG EamA-like transporter family
MDGJMAFB_01317 1e-110 rsfA_1
MDGJMAFB_01318 3.1e-36 ywzC S Belongs to the UPF0741 family
MDGJMAFB_01319 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
MDGJMAFB_01320 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
MDGJMAFB_01321 5.3e-78 yffB K Transcriptional regulator
MDGJMAFB_01322 7.4e-237 mmr U Major Facilitator Superfamily
MDGJMAFB_01324 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDGJMAFB_01325 3.3e-71 ywhA K Transcriptional regulator
MDGJMAFB_01326 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MDGJMAFB_01327 5.1e-119 ywhC S Peptidase family M50
MDGJMAFB_01328 2e-94 ywhD S YwhD family
MDGJMAFB_01329 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MDGJMAFB_01330 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MDGJMAFB_01331 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
MDGJMAFB_01332 5.1e-34 ywhH S Aminoacyl-tRNA editing domain
MDGJMAFB_01334 8e-80 S aspartate phosphatase
MDGJMAFB_01335 2.3e-198 ywhK CO amine dehydrogenase activity
MDGJMAFB_01336 4e-243 ywhL CO amine dehydrogenase activity
MDGJMAFB_01338 2.9e-248 L Peptidase, M16
MDGJMAFB_01339 2.1e-216 2.7.1.26, 2.7.7.2 L Peptidase, M16
MDGJMAFB_01340 3.5e-236 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MDGJMAFB_01341 3.7e-131 cbiO V ABC transporter
MDGJMAFB_01343 5.4e-269 C Fe-S oxidoreductases
MDGJMAFB_01344 1e-07 S Bacteriocin subtilosin A
MDGJMAFB_01345 4.7e-73 ywiB S protein conserved in bacteria
MDGJMAFB_01346 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MDGJMAFB_01347 1.3e-213 narK P COG2223 Nitrate nitrite transporter
MDGJMAFB_01348 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
MDGJMAFB_01349 1.1e-138 ywiC S YwiC-like protein
MDGJMAFB_01350 7e-86 arfM T cyclic nucleotide binding
MDGJMAFB_01351 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDGJMAFB_01352 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
MDGJMAFB_01353 1.1e-93 narJ 1.7.5.1 C nitrate reductase
MDGJMAFB_01354 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
MDGJMAFB_01355 2.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDGJMAFB_01356 0.0 ywjA V ABC transporter
MDGJMAFB_01357 4.8e-96 ywjB H RibD C-terminal domain
MDGJMAFB_01358 2.7e-42 ywjC
MDGJMAFB_01359 3.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MDGJMAFB_01360 5.8e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MDGJMAFB_01361 0.0 fadF C COG0247 Fe-S oxidoreductase
MDGJMAFB_01362 9.7e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MDGJMAFB_01363 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDGJMAFB_01364 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDGJMAFB_01365 1.2e-91 ywjG S Domain of unknown function (DUF2529)
MDGJMAFB_01366 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
MDGJMAFB_01367 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MDGJMAFB_01368 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MDGJMAFB_01369 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDGJMAFB_01370 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MDGJMAFB_01371 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MDGJMAFB_01372 1.1e-32 rpmE J Binds the 23S rRNA
MDGJMAFB_01373 5.4e-104 tdk 2.7.1.21 F thymidine kinase
MDGJMAFB_01374 0.0 sfcA 1.1.1.38 C malic enzyme
MDGJMAFB_01375 8.6e-160 ywkB S Membrane transport protein
MDGJMAFB_01376 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MDGJMAFB_01377 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDGJMAFB_01378 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDGJMAFB_01379 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDGJMAFB_01381 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
MDGJMAFB_01382 3e-111 spoIIR S stage II sporulation protein R
MDGJMAFB_01383 4.7e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
MDGJMAFB_01384 5.2e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDGJMAFB_01385 1.7e-91 mntP P Probably functions as a manganese efflux pump
MDGJMAFB_01386 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDGJMAFB_01387 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MDGJMAFB_01388 7.2e-95 ywlG S Belongs to the UPF0340 family
MDGJMAFB_01389 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDGJMAFB_01390 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDGJMAFB_01391 1.6e-61 atpI S ATP synthase
MDGJMAFB_01392 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
MDGJMAFB_01393 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDGJMAFB_01394 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDGJMAFB_01395 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDGJMAFB_01396 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDGJMAFB_01397 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDGJMAFB_01398 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDGJMAFB_01399 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MDGJMAFB_01400 4.8e-87 ywmA
MDGJMAFB_01401 1.3e-32 ywzB S membrane
MDGJMAFB_01402 5.3e-133 ywmB S TATA-box binding
MDGJMAFB_01403 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDGJMAFB_01404 4.6e-175 spoIID D Stage II sporulation protein D
MDGJMAFB_01405 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
MDGJMAFB_01406 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
MDGJMAFB_01408 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MDGJMAFB_01409 1.3e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MDGJMAFB_01410 1.3e-103 S response regulator aspartate phosphatase
MDGJMAFB_01411 3e-84 ywmF S Peptidase M50
MDGJMAFB_01412 3.8e-11 csbD K CsbD-like
MDGJMAFB_01413 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MDGJMAFB_01414 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MDGJMAFB_01415 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MDGJMAFB_01416 1.7e-64 ywnA K Transcriptional regulator
MDGJMAFB_01417 5.3e-113 ywnB S NAD(P)H-binding
MDGJMAFB_01418 2.6e-59 ywnC S Family of unknown function (DUF5362)
MDGJMAFB_01419 1.6e-143 mta K transcriptional
MDGJMAFB_01420 3.5e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDGJMAFB_01421 8.3e-70 ywnF S Family of unknown function (DUF5392)
MDGJMAFB_01422 5.7e-09 ywnC S Family of unknown function (DUF5362)
MDGJMAFB_01423 7e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MDGJMAFB_01424 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MDGJMAFB_01425 7.8e-73 ywnJ S VanZ like family
MDGJMAFB_01426 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MDGJMAFB_01427 1.6e-58 nrgB K Belongs to the P(II) protein family
MDGJMAFB_01428 4.3e-225 amt P Ammonium transporter
MDGJMAFB_01429 1.2e-77
MDGJMAFB_01430 6.8e-104 phzA Q Isochorismatase family
MDGJMAFB_01431 2.4e-240 ywoD EGP Major facilitator superfamily
MDGJMAFB_01432 7e-278 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
MDGJMAFB_01433 1.4e-230 ywoF P Right handed beta helix region
MDGJMAFB_01434 2.7e-211 ywoG EGP Major facilitator Superfamily
MDGJMAFB_01435 2.1e-70 ywoH K COG1846 Transcriptional regulators
MDGJMAFB_01436 3e-44 spoIIID K Stage III sporulation protein D
MDGJMAFB_01437 3.5e-180 mbl D Rod shape-determining protein
MDGJMAFB_01438 1.4e-123 flhO N flagellar basal body
MDGJMAFB_01439 2.6e-141 flhP N flagellar basal body
MDGJMAFB_01440 2e-197 S aspartate phosphatase
MDGJMAFB_01441 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MDGJMAFB_01442 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDGJMAFB_01443 4.9e-146 ywpD T Histidine kinase
MDGJMAFB_01444 2.7e-46 srtA 3.4.22.70 M Sortase family
MDGJMAFB_01445 1.1e-66 ywpF S YwpF-like protein
MDGJMAFB_01446 3.8e-66 ywpG
MDGJMAFB_01447 3.7e-57 ssbB L Single-stranded DNA-binding protein
MDGJMAFB_01448 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
MDGJMAFB_01449 2.2e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
MDGJMAFB_01450 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MDGJMAFB_01451 1.4e-308 ywqB S SWIM zinc finger
MDGJMAFB_01452 1.2e-17
MDGJMAFB_01453 2e-116 ywqC M biosynthesis protein
MDGJMAFB_01454 4.9e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MDGJMAFB_01455 1.1e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MDGJMAFB_01456 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDGJMAFB_01457 2.4e-152 ywqG S Domain of unknown function (DUF1963)
MDGJMAFB_01458 1e-19 S Domain of unknown function (DUF5082)
MDGJMAFB_01459 1.1e-38 ywqI S Family of unknown function (DUF5344)
MDGJMAFB_01460 1.1e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
MDGJMAFB_01461 7.9e-43
MDGJMAFB_01462 5.2e-17
MDGJMAFB_01463 3.4e-79 ywqJ S Pre-toxin TG
MDGJMAFB_01464 6.5e-76
MDGJMAFB_01465 4.8e-50
MDGJMAFB_01467 5.4e-97
MDGJMAFB_01468 5.9e-121 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MDGJMAFB_01469 1.4e-161 K Transcriptional regulator
MDGJMAFB_01470 2.2e-99 ywqN S NAD(P)H-dependent
MDGJMAFB_01472 9.3e-87 ywrA P COG2059 Chromate transport protein ChrA
MDGJMAFB_01473 3.5e-103 ywrB P Chromate transporter
MDGJMAFB_01474 8e-82 ywrC K Transcriptional regulator
MDGJMAFB_01475 6.1e-304 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MDGJMAFB_01476 5e-54 S Domain of unknown function (DUF4181)
MDGJMAFB_01477 3.1e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MDGJMAFB_01478 3.7e-12
MDGJMAFB_01479 1.2e-210 cotH M Spore Coat
MDGJMAFB_01480 8.2e-131 cotB
MDGJMAFB_01481 4.9e-125 ywrJ
MDGJMAFB_01482 1.6e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MDGJMAFB_01483 1.1e-169 alsR K LysR substrate binding domain
MDGJMAFB_01484 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MDGJMAFB_01485 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MDGJMAFB_01486 1.7e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
MDGJMAFB_01487 1.8e-47 ywsA S Protein of unknown function (DUF3892)
MDGJMAFB_01488 8.7e-93 batE T Sh3 type 3 domain protein
MDGJMAFB_01489 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MDGJMAFB_01490 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
MDGJMAFB_01491 8.6e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MDGJMAFB_01492 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MDGJMAFB_01493 9.3e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDGJMAFB_01494 1.2e-177 rbsR K transcriptional
MDGJMAFB_01495 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
MDGJMAFB_01496 8.6e-70 pgsC S biosynthesis protein
MDGJMAFB_01497 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MDGJMAFB_01498 3.6e-21 ywtC
MDGJMAFB_01499 2e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MDGJMAFB_01500 3.5e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
MDGJMAFB_01501 2.4e-170 ywtF K Transcriptional regulator
MDGJMAFB_01502 7.8e-247 ywtG EGP Major facilitator Superfamily
MDGJMAFB_01503 1.5e-211 gerAC S Spore germination protein
MDGJMAFB_01504 5.4e-198 gerBB E Spore germination protein
MDGJMAFB_01505 8.7e-265 gerBA EG Spore germination protein
MDGJMAFB_01506 4.6e-190 pmi 5.3.1.8 G mannose-6-phosphate isomerase
MDGJMAFB_01507 3e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDGJMAFB_01508 3.5e-260
MDGJMAFB_01509 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MDGJMAFB_01510 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MDGJMAFB_01511 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MDGJMAFB_01512 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
MDGJMAFB_01513 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MDGJMAFB_01514 7e-150 tagG GM Transport permease protein
MDGJMAFB_01515 5.1e-266 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MDGJMAFB_01516 1.9e-36 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MDGJMAFB_01517 1.9e-54 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MDGJMAFB_01518 3e-39 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MDGJMAFB_01519 7.5e-93 ggaA M Glycosyltransferase like family 2
MDGJMAFB_01520 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDGJMAFB_01521 6.5e-57
MDGJMAFB_01522 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MDGJMAFB_01523 1e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDGJMAFB_01524 1.8e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MDGJMAFB_01525 6e-38
MDGJMAFB_01526 0.0 lytB 3.5.1.28 D Stage II sporulation protein
MDGJMAFB_01527 3.3e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MDGJMAFB_01528 1.3e-111 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MDGJMAFB_01529 9.7e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDGJMAFB_01530 3.1e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
MDGJMAFB_01531 2e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDGJMAFB_01532 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
MDGJMAFB_01533 9.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
MDGJMAFB_01534 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
MDGJMAFB_01535 1.7e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
MDGJMAFB_01536 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MDGJMAFB_01537 6e-163 yvhJ K Transcriptional regulator
MDGJMAFB_01538 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MDGJMAFB_01539 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MDGJMAFB_01540 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDGJMAFB_01541 4.8e-154 degV S protein conserved in bacteria
MDGJMAFB_01542 1.5e-266 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MDGJMAFB_01543 8.3e-45 comFB S Late competence development protein ComFB
MDGJMAFB_01544 2e-124 comFC S Phosphoribosyl transferase domain
MDGJMAFB_01545 2e-73 yvyF S flagellar protein
MDGJMAFB_01546 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
MDGJMAFB_01547 4.6e-77 flgN NOU FlgN protein
MDGJMAFB_01548 2.7e-264 flgK N flagellar hook-associated protein
MDGJMAFB_01549 3.9e-154 flgL N Belongs to the bacterial flagellin family
MDGJMAFB_01550 5.7e-50 yviE
MDGJMAFB_01551 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MDGJMAFB_01552 5.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MDGJMAFB_01553 1.2e-123 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MDGJMAFB_01554 1.2e-55 flaG N flagellar protein FlaG
MDGJMAFB_01555 1.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MDGJMAFB_01556 2.9e-69 fliS N flagellar protein FliS
MDGJMAFB_01557 1.9e-08 fliT S bacterial-type flagellum organization
MDGJMAFB_01558 2.8e-66
MDGJMAFB_01559 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDGJMAFB_01560 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDGJMAFB_01561 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDGJMAFB_01562 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MDGJMAFB_01563 3e-51 cccB C COG2010 Cytochrome c, mono- and diheme variants
MDGJMAFB_01564 1.6e-123 ftsE D cell division ATP-binding protein FtsE
MDGJMAFB_01565 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MDGJMAFB_01566 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MDGJMAFB_01567 5.3e-56 swrA S Swarming motility protein
MDGJMAFB_01568 3.2e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDGJMAFB_01569 5.6e-226 yvkA EGP Major facilitator Superfamily
MDGJMAFB_01570 2e-100 yvkB K Transcriptional regulator
MDGJMAFB_01571 0.0 yvkC 2.7.9.2 GT Phosphotransferase
MDGJMAFB_01572 1.2e-30 csbA S protein conserved in bacteria
MDGJMAFB_01573 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDGJMAFB_01574 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDGJMAFB_01575 2.9e-26 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MDGJMAFB_01576 5.7e-33 yvkN
MDGJMAFB_01577 1.8e-48 yvlA
MDGJMAFB_01578 1.7e-167 yvlB S Putative adhesin
MDGJMAFB_01579 2.6e-26 pspB KT PspC domain
MDGJMAFB_01580 1.2e-50 yvlD S Membrane
MDGJMAFB_01581 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
MDGJMAFB_01582 3.6e-134 yvoA K transcriptional
MDGJMAFB_01583 7e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDGJMAFB_01584 1.7e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MDGJMAFB_01585 2.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDGJMAFB_01586 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDGJMAFB_01587 5.3e-162 yvoD P COG0370 Fe2 transport system protein B
MDGJMAFB_01588 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MDGJMAFB_01589 8.7e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MDGJMAFB_01590 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
MDGJMAFB_01591 3.8e-139 yvpB NU protein conserved in bacteria
MDGJMAFB_01592 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MDGJMAFB_01593 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MDGJMAFB_01594 8.4e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MDGJMAFB_01595 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MDGJMAFB_01596 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MDGJMAFB_01597 4.2e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MDGJMAFB_01598 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MDGJMAFB_01599 8.8e-113 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MDGJMAFB_01600 2.2e-78
MDGJMAFB_01601 1e-252
MDGJMAFB_01603 0.0 msbA2 3.6.3.44 V ABC transporter
MDGJMAFB_01604 2.2e-276 S COG0457 FOG TPR repeat
MDGJMAFB_01605 2.3e-97 usp CBM50 M protein conserved in bacteria
MDGJMAFB_01606 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDGJMAFB_01607 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MDGJMAFB_01608 5.7e-166 rapZ S Displays ATPase and GTPase activities
MDGJMAFB_01609 2.1e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MDGJMAFB_01610 1.4e-170 whiA K May be required for sporulation
MDGJMAFB_01611 1.6e-36 crh G Phosphocarrier protein Chr
MDGJMAFB_01612 1.5e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
MDGJMAFB_01613 9.7e-32
MDGJMAFB_01614 1.9e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDGJMAFB_01615 1.5e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MDGJMAFB_01616 4.7e-140 yvcR V ABC transporter, ATP-binding protein
MDGJMAFB_01617 0.0 yxdM V ABC transporter (permease)
MDGJMAFB_01618 4.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDGJMAFB_01619 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MDGJMAFB_01620 2.8e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
MDGJMAFB_01621 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
MDGJMAFB_01622 1.6e-105 yvdD 3.2.2.10 S Belongs to the LOG family
MDGJMAFB_01623 1.7e-171 yvdE K Transcriptional regulator
MDGJMAFB_01624 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MDGJMAFB_01625 1.1e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
MDGJMAFB_01626 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
MDGJMAFB_01627 6.6e-148 malD P transport
MDGJMAFB_01628 2.4e-156 malA S Protein of unknown function (DUF1189)
MDGJMAFB_01629 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MDGJMAFB_01630 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MDGJMAFB_01631 2.8e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MDGJMAFB_01632 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDGJMAFB_01634 1.2e-182 S Patatin-like phospholipase
MDGJMAFB_01635 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
MDGJMAFB_01636 6.3e-93 yvdQ S Protein of unknown function (DUF3231)
MDGJMAFB_01637 2.7e-49 sugE P Small Multidrug Resistance protein
MDGJMAFB_01638 6.7e-51 ykkC P Small Multidrug Resistance protein
MDGJMAFB_01639 7.4e-106 yvdT K Transcriptional regulator
MDGJMAFB_01640 1.8e-295 yveA E amino acid
MDGJMAFB_01641 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MDGJMAFB_01642 4.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
MDGJMAFB_01643 3.2e-261 pbpE V Beta-lactamase
MDGJMAFB_01644 2.2e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MDGJMAFB_01645 1.1e-72 MA20_18690 S Protein of unknown function (DUF3237)
MDGJMAFB_01646 4.6e-93 padC Q Phenolic acid decarboxylase
MDGJMAFB_01648 6e-186 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MDGJMAFB_01649 6.3e-76 slr K transcriptional
MDGJMAFB_01650 1.5e-121 ywqC M biosynthesis protein
MDGJMAFB_01651 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
MDGJMAFB_01652 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MDGJMAFB_01653 3.2e-222 epsD GT4 M Glycosyl transferase 4-like
MDGJMAFB_01654 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MDGJMAFB_01655 3.2e-217 epsF GT4 M Glycosyl transferases group 1
MDGJMAFB_01656 5.4e-206 epsG S EpsG family
MDGJMAFB_01657 4.9e-193 epsH GT2 S Glycosyltransferase like family 2
MDGJMAFB_01658 4.4e-205 epsI GM pyruvyl transferase
MDGJMAFB_01659 2.4e-192 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
MDGJMAFB_01660 1.4e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDGJMAFB_01661 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MDGJMAFB_01662 5.1e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
MDGJMAFB_01663 2e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
MDGJMAFB_01664 1.1e-186 yvfF GM Exopolysaccharide biosynthesis protein
MDGJMAFB_01665 1e-31 yvfG S YvfG protein
MDGJMAFB_01666 1.1e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MDGJMAFB_01667 7.5e-308 yvfH C L-lactate permease
MDGJMAFB_01668 1e-112 yvfI K COG2186 Transcriptional regulators
MDGJMAFB_01669 1.8e-184 lacR K Transcriptional regulator
MDGJMAFB_01670 6.7e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
MDGJMAFB_01671 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
MDGJMAFB_01672 2.7e-149 ganQ P transport
MDGJMAFB_01673 0.0 lacA 3.2.1.23 G beta-galactosidase
MDGJMAFB_01674 9.2e-250 galA 3.2.1.89 G arabinogalactan
MDGJMAFB_01675 6.5e-197 rsbU 3.1.3.3 T response regulator
MDGJMAFB_01676 1.1e-155 rsbQ S Alpha/beta hydrolase family
MDGJMAFB_01677 1.1e-159 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
MDGJMAFB_01678 4.5e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
MDGJMAFB_01679 1e-196 desK 2.7.13.3 T Histidine kinase
MDGJMAFB_01680 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDGJMAFB_01681 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MDGJMAFB_01682 4.6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MDGJMAFB_01683 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MDGJMAFB_01684 5.2e-195 yvbX S Glycosyl hydrolase
MDGJMAFB_01685 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
MDGJMAFB_01686 7.2e-156 yvbV EG EamA-like transporter family
MDGJMAFB_01687 3.9e-159 yvbU K Transcriptional regulator
MDGJMAFB_01688 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDGJMAFB_01689 5.5e-203 araR K transcriptional
MDGJMAFB_01690 1.6e-252 araE EGP Major facilitator Superfamily
MDGJMAFB_01691 1.8e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MDGJMAFB_01692 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDGJMAFB_01693 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MDGJMAFB_01694 1.6e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDGJMAFB_01695 6.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MDGJMAFB_01696 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDGJMAFB_01697 6.5e-81 yvbK 3.1.3.25 K acetyltransferase
MDGJMAFB_01698 0.0 tcaA S response to antibiotic
MDGJMAFB_01699 2.3e-122 exoY M Membrane
MDGJMAFB_01700 1.9e-112 yvbH S YvbH-like oligomerisation region
MDGJMAFB_01701 2.4e-102 yvbG U UPF0056 membrane protein
MDGJMAFB_01702 3.5e-97 yvbF K Belongs to the GbsR family
MDGJMAFB_01703 4.4e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MDGJMAFB_01704 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MDGJMAFB_01705 1.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MDGJMAFB_01706 2.5e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MDGJMAFB_01707 3.3e-60 yvbF K Belongs to the GbsR family
MDGJMAFB_01708 1.1e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MDGJMAFB_01709 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MDGJMAFB_01710 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MDGJMAFB_01711 2.4e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MDGJMAFB_01712 4.1e-221 NT chemotaxis protein
MDGJMAFB_01713 2.2e-54 yodB K transcriptional
MDGJMAFB_01714 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
MDGJMAFB_01715 4e-69 K transcriptional
MDGJMAFB_01716 7.5e-36 yvzC K Transcriptional
MDGJMAFB_01717 6.5e-150 yvaM S Serine aminopeptidase, S33
MDGJMAFB_01718 2.4e-23 secG U Preprotein translocase subunit SecG
MDGJMAFB_01719 5.6e-143 est 3.1.1.1 S Carboxylesterase
MDGJMAFB_01720 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDGJMAFB_01721 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MDGJMAFB_01723 7.7e-130 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MDGJMAFB_01724 2.7e-97 K Bacterial regulatory proteins, tetR family
MDGJMAFB_01725 2.4e-54 yvaE P Small Multidrug Resistance protein
MDGJMAFB_01726 5.7e-73 yvaD S Family of unknown function (DUF5360)
MDGJMAFB_01727 0.0 yvaC S Fusaric acid resistance protein-like
MDGJMAFB_01728 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MDGJMAFB_01729 1.1e-195 yvaA 1.1.1.371 S Oxidoreductase
MDGJMAFB_01730 2.2e-48 csoR S transcriptional
MDGJMAFB_01731 5.9e-29 copZ P Copper resistance protein CopZ
MDGJMAFB_01732 0.0 copA 3.6.3.54 P P-type ATPase
MDGJMAFB_01733 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MDGJMAFB_01734 1.6e-104 bdbD O Thioredoxin
MDGJMAFB_01735 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
MDGJMAFB_01736 1.6e-106 yvgT S membrane
MDGJMAFB_01738 0.0 helD 3.6.4.12 L DNA helicase
MDGJMAFB_01739 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MDGJMAFB_01740 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MDGJMAFB_01741 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MDGJMAFB_01742 5.4e-86 yvgO
MDGJMAFB_01743 1.1e-155 yvgN S reductase
MDGJMAFB_01744 3.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
MDGJMAFB_01745 1.4e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MDGJMAFB_01746 7e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
MDGJMAFB_01747 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MDGJMAFB_01748 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
MDGJMAFB_01749 6.5e-16 S Small spore protein J (Spore_SspJ)
MDGJMAFB_01750 4.9e-236 yvsH E Arginine ornithine antiporter
MDGJMAFB_01751 3.4e-177 fhuD P ABC transporter
MDGJMAFB_01752 2.7e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDGJMAFB_01753 9e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDGJMAFB_01754 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
MDGJMAFB_01755 1.1e-175 M Efflux transporter rnd family, mfp subunit
MDGJMAFB_01756 7.9e-123 macB V ABC transporter, ATP-binding protein
MDGJMAFB_01757 9e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
MDGJMAFB_01758 1.3e-64 yvrL S Regulatory protein YrvL
MDGJMAFB_01759 1.1e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
MDGJMAFB_01760 2.4e-19 S YvrJ protein family
MDGJMAFB_01761 9.5e-98 yvrI K RNA polymerase
MDGJMAFB_01762 3.6e-22
MDGJMAFB_01763 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDGJMAFB_01764 0.0 T PhoQ Sensor
MDGJMAFB_01765 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
MDGJMAFB_01766 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MDGJMAFB_01767 8.4e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MDGJMAFB_01768 1.6e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDGJMAFB_01769 5.6e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MDGJMAFB_01770 3.6e-100 yvqK 2.5.1.17 S Adenosyltransferase
MDGJMAFB_01771 1.4e-226 yvqJ EGP Major facilitator Superfamily
MDGJMAFB_01772 7.3e-62 liaI S membrane
MDGJMAFB_01773 9.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MDGJMAFB_01774 1.2e-123 liaG S Putative adhesin
MDGJMAFB_01775 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MDGJMAFB_01776 3.5e-186 vraS 2.7.13.3 T Histidine kinase
MDGJMAFB_01777 3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDGJMAFB_01778 8.5e-183 gerAC S Spore germination B3/ GerAC like, C-terminal
MDGJMAFB_01779 3.8e-196 gerAB E Spore germination protein
MDGJMAFB_01780 3.1e-246 gerAA EG Spore germination protein
MDGJMAFB_01781 3.9e-24 S Protein of unknown function (DUF3970)
MDGJMAFB_01782 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDGJMAFB_01783 4.3e-158 yuxN K Transcriptional regulator
MDGJMAFB_01784 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
MDGJMAFB_01785 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDGJMAFB_01786 3.1e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDGJMAFB_01787 1.2e-79 dps P Ferritin-like domain
MDGJMAFB_01788 8.9e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MDGJMAFB_01789 5.5e-301 pepF2 E COG1164 Oligoendopeptidase F
MDGJMAFB_01790 5.6e-66 S YusW-like protein
MDGJMAFB_01791 3.9e-153 yusV 3.6.3.34 HP ABC transporter
MDGJMAFB_01792 1.1e-46 yusU S Protein of unknown function (DUF2573)
MDGJMAFB_01793 3.7e-157 yusT K LysR substrate binding domain
MDGJMAFB_01794 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MDGJMAFB_01795 2.7e-64 yusQ S Tautomerase enzyme
MDGJMAFB_01796 9.4e-292 yusP P Major facilitator superfamily
MDGJMAFB_01797 1e-73 yusO K Iron dependent repressor, N-terminal DNA binding domain
MDGJMAFB_01798 5.4e-53 yusN M Coat F domain
MDGJMAFB_01799 5.1e-40
MDGJMAFB_01800 1.1e-164 fadM E Proline dehydrogenase
MDGJMAFB_01801 8.1e-09 S YuzL-like protein
MDGJMAFB_01802 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MDGJMAFB_01803 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
MDGJMAFB_01804 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MDGJMAFB_01805 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
MDGJMAFB_01806 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MDGJMAFB_01807 1.1e-39 yusG S Protein of unknown function (DUF2553)
MDGJMAFB_01808 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
MDGJMAFB_01809 5.6e-55 traF CO Thioredoxin
MDGJMAFB_01810 3.2e-56 yusD S SCP-2 sterol transfer family
MDGJMAFB_01811 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDGJMAFB_01812 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
MDGJMAFB_01813 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
MDGJMAFB_01814 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MDGJMAFB_01815 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MDGJMAFB_01816 4.1e-245 sufD O assembly protein SufD
MDGJMAFB_01817 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MDGJMAFB_01818 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MDGJMAFB_01819 3.5e-271 sufB O FeS cluster assembly
MDGJMAFB_01820 2.9e-66 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDGJMAFB_01821 2.3e-41
MDGJMAFB_01823 4.2e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MDGJMAFB_01824 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
MDGJMAFB_01825 1.1e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MDGJMAFB_01826 4.2e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
MDGJMAFB_01827 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
MDGJMAFB_01828 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
MDGJMAFB_01829 3.3e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
MDGJMAFB_01830 3.3e-135 yurK K UTRA
MDGJMAFB_01831 1.2e-205 msmX P Belongs to the ABC transporter superfamily
MDGJMAFB_01832 2e-168 bsn L Ribonuclease
MDGJMAFB_01833 3.2e-231 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MDGJMAFB_01834 2.1e-238 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MDGJMAFB_01836 1e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MDGJMAFB_01837 6.9e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
MDGJMAFB_01838 3.7e-151 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MDGJMAFB_01839 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MDGJMAFB_01840 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MDGJMAFB_01841 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MDGJMAFB_01842 1.1e-283 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MDGJMAFB_01843 1.3e-224 pbuX F xanthine
MDGJMAFB_01844 8.8e-235 pbuX F Permease family
MDGJMAFB_01845 9.8e-302 pucR QT COG2508 Regulator of polyketide synthase expression
MDGJMAFB_01846 9.6e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MDGJMAFB_01847 3e-62 yunG
MDGJMAFB_01848 4.3e-171 yunF S Protein of unknown function DUF72
MDGJMAFB_01849 2e-141 yunE S membrane transporter protein
MDGJMAFB_01850 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MDGJMAFB_01851 5.3e-47 yunC S Domain of unknown function (DUF1805)
MDGJMAFB_01852 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
MDGJMAFB_01853 4.5e-196 lytH M Peptidase, M23
MDGJMAFB_01854 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MDGJMAFB_01855 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDGJMAFB_01856 9.7e-48 yutD S protein conserved in bacteria
MDGJMAFB_01857 5e-75 yutE S Protein of unknown function DUF86
MDGJMAFB_01858 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDGJMAFB_01859 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MDGJMAFB_01860 2.9e-198 yutH S Spore coat protein
MDGJMAFB_01861 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
MDGJMAFB_01862 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MDGJMAFB_01863 2.5e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MDGJMAFB_01864 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
MDGJMAFB_01865 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
MDGJMAFB_01866 8.7e-56 yuzD S protein conserved in bacteria
MDGJMAFB_01867 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
MDGJMAFB_01868 3.2e-39 yuzB S Belongs to the UPF0349 family
MDGJMAFB_01869 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MDGJMAFB_01870 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MDGJMAFB_01871 3.7e-63 erpA S Belongs to the HesB IscA family
MDGJMAFB_01872 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDGJMAFB_01873 9e-118 paiB K Putative FMN-binding domain
MDGJMAFB_01874 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDGJMAFB_01876 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
MDGJMAFB_01877 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
MDGJMAFB_01878 3.2e-26 yuiB S Putative membrane protein
MDGJMAFB_01879 4.7e-117 yuiC S protein conserved in bacteria
MDGJMAFB_01880 1.2e-77 yuiD S protein conserved in bacteria
MDGJMAFB_01881 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MDGJMAFB_01882 3.9e-211 yuiF S antiporter
MDGJMAFB_01883 1.1e-93 bioY S Biotin biosynthesis protein
MDGJMAFB_01884 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
MDGJMAFB_01885 9.6e-166 besA S Putative esterase
MDGJMAFB_01886 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MDGJMAFB_01887 1.1e-225 entC 5.4.4.2 HQ Isochorismate synthase
MDGJMAFB_01888 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
MDGJMAFB_01889 3.2e-175 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
MDGJMAFB_01890 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDGJMAFB_01891 1.1e-35 mbtH S MbtH-like protein
MDGJMAFB_01892 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
MDGJMAFB_01893 3e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MDGJMAFB_01894 6.5e-229 yukF QT Transcriptional regulator
MDGJMAFB_01895 2.8e-45 esxA S Belongs to the WXG100 family
MDGJMAFB_01896 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
MDGJMAFB_01897 1.5e-210 essB S WXG100 protein secretion system (Wss), protein YukC
MDGJMAFB_01898 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MDGJMAFB_01899 0.0 esaA S type VII secretion protein EsaA
MDGJMAFB_01900 3.2e-59 yueC S Family of unknown function (DUF5383)
MDGJMAFB_01901 1.7e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDGJMAFB_01902 4.8e-96 yueE S phosphohydrolase
MDGJMAFB_01903 2.9e-24 S Protein of unknown function (DUF2642)
MDGJMAFB_01904 3.6e-13 S Protein of unknown function (DUF2283)
MDGJMAFB_01905 1.2e-189 yueF S transporter activity
MDGJMAFB_01906 1.7e-31 yueG S Spore germination protein gerPA/gerPF
MDGJMAFB_01907 2.8e-38 yueH S YueH-like protein
MDGJMAFB_01908 7.9e-67 yueI S Protein of unknown function (DUF1694)
MDGJMAFB_01909 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
MDGJMAFB_01910 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDGJMAFB_01911 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
MDGJMAFB_01912 1.1e-22 yuzC
MDGJMAFB_01914 2.3e-136 comQ H Belongs to the FPP GGPP synthase family
MDGJMAFB_01916 0.0 comP 2.7.13.3 T Histidine kinase
MDGJMAFB_01917 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDGJMAFB_01918 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
MDGJMAFB_01919 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MDGJMAFB_01920 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDGJMAFB_01921 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDGJMAFB_01922 6.4e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDGJMAFB_01923 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDGJMAFB_01924 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDGJMAFB_01925 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MDGJMAFB_01926 3.2e-14
MDGJMAFB_01927 1.3e-233 maeN C COG3493 Na citrate symporter
MDGJMAFB_01928 5e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
MDGJMAFB_01929 1.9e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
MDGJMAFB_01930 2.1e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MDGJMAFB_01931 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MDGJMAFB_01932 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
MDGJMAFB_01933 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MDGJMAFB_01934 6.3e-78 yufK S Family of unknown function (DUF5366)
MDGJMAFB_01935 1.8e-74 yuxK S protein conserved in bacteria
MDGJMAFB_01936 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
MDGJMAFB_01937 3.8e-185 yuxJ EGP Major facilitator Superfamily
MDGJMAFB_01939 4.2e-115 kapD L the KinA pathway to sporulation
MDGJMAFB_01940 7.4e-70 kapB G Kinase associated protein B
MDGJMAFB_01941 1.3e-232 T PhoQ Sensor
MDGJMAFB_01942 9.9e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MDGJMAFB_01943 1.1e-40 yugE S Domain of unknown function (DUF1871)
MDGJMAFB_01944 4.2e-155 yugF I Hydrolase
MDGJMAFB_01945 1.6e-85 alaR K Transcriptional regulator
MDGJMAFB_01946 2.1e-199 yugH 2.6.1.1 E Aminotransferase
MDGJMAFB_01947 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MDGJMAFB_01948 1.1e-34 yuzA S Domain of unknown function (DUF378)
MDGJMAFB_01949 3.8e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MDGJMAFB_01950 1.8e-228 yugK C Dehydrogenase
MDGJMAFB_01951 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
MDGJMAFB_01953 2.8e-72 yugN S YugN-like family
MDGJMAFB_01954 2.2e-182 yugO P COG1226 Kef-type K transport systems
MDGJMAFB_01955 5.4e-53 mstX S Membrane-integrating protein Mistic
MDGJMAFB_01956 2.3e-38
MDGJMAFB_01957 1.4e-116 yugP S Zn-dependent protease
MDGJMAFB_01958 1.3e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
MDGJMAFB_01959 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MDGJMAFB_01960 2.1e-72 yugU S Uncharacterised protein family UPF0047
MDGJMAFB_01961 1e-35
MDGJMAFB_01962 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
MDGJMAFB_01963 9.3e-225 mcpA NT chemotaxis protein
MDGJMAFB_01964 6.9e-220 mcpA NT chemotaxis protein
MDGJMAFB_01965 1.9e-294 mcpA NT chemotaxis protein
MDGJMAFB_01966 9.6e-238 mcpA NT chemotaxis protein
MDGJMAFB_01967 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
MDGJMAFB_01968 3.8e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
MDGJMAFB_01969 7.7e-277 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MDGJMAFB_01970 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MDGJMAFB_01971 8.2e-251 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MDGJMAFB_01972 7.4e-183 ygjR S Oxidoreductase
MDGJMAFB_01973 1.3e-194 yubA S transporter activity
MDGJMAFB_01974 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MDGJMAFB_01976 1.1e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
MDGJMAFB_01977 1.9e-273 yubD P Major Facilitator Superfamily
MDGJMAFB_01978 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDGJMAFB_01979 1e-38 yiaA S yiaA/B two helix domain
MDGJMAFB_01980 6e-236 ktrB P Potassium
MDGJMAFB_01981 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
MDGJMAFB_01982 2.2e-91 yuaB
MDGJMAFB_01983 5.5e-95 yuaC K Belongs to the GbsR family
MDGJMAFB_01984 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MDGJMAFB_01985 4.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
MDGJMAFB_01986 7.9e-108 yuaD
MDGJMAFB_01987 3.9e-84 yuaE S DinB superfamily
MDGJMAFB_01988 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MDGJMAFB_01989 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
MDGJMAFB_01990 3.4e-94 M1-753 M FR47-like protein
MDGJMAFB_01991 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
MDGJMAFB_01992 3.4e-39 S COG NOG14552 non supervised orthologous group
MDGJMAFB_01997 2e-08
MDGJMAFB_02004 1.3e-09
MDGJMAFB_02005 7.8e-08
MDGJMAFB_02014 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MDGJMAFB_02015 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MDGJMAFB_02016 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
MDGJMAFB_02017 1.3e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MDGJMAFB_02018 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MDGJMAFB_02019 3.8e-76 tspO T membrane
MDGJMAFB_02020 1.3e-204 cotI S Spore coat protein
MDGJMAFB_02021 1.8e-217 cotSA M Glycosyl transferases group 1
MDGJMAFB_02022 9.7e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
MDGJMAFB_02024 9.7e-233 ytcC M Glycosyltransferase Family 4
MDGJMAFB_02025 5.9e-177 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
MDGJMAFB_02026 3.2e-242 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDGJMAFB_02027 1.9e-152 galU 2.7.7.9 M Nucleotidyl transferase
MDGJMAFB_02028 4.4e-132 dksA T COG1734 DnaK suppressor protein
MDGJMAFB_02029 3.6e-271 menF 5.4.4.2 HQ Isochorismate synthase
MDGJMAFB_02030 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MDGJMAFB_02031 1.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MDGJMAFB_02032 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MDGJMAFB_02033 3.3e-272 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MDGJMAFB_02034 5.1e-212 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MDGJMAFB_02035 7.5e-132 troA P Belongs to the bacterial solute-binding protein 9 family
MDGJMAFB_02036 3e-136 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MDGJMAFB_02037 1.4e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MDGJMAFB_02038 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MDGJMAFB_02039 1.1e-24 S Domain of Unknown Function (DUF1540)
MDGJMAFB_02040 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MDGJMAFB_02041 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
MDGJMAFB_02042 3.6e-41 rpmE2 J Ribosomal protein L31
MDGJMAFB_02043 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MDGJMAFB_02044 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDGJMAFB_02045 2.4e-72 ytkA S YtkA-like
MDGJMAFB_02047 2.1e-76 dps P Belongs to the Dps family
MDGJMAFB_02048 6e-62 ytkC S Bacteriophage holin family
MDGJMAFB_02049 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MDGJMAFB_02050 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MDGJMAFB_02051 1.4e-144 ytlC P ABC transporter
MDGJMAFB_02052 1.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MDGJMAFB_02053 2.7e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MDGJMAFB_02054 1.2e-38 ytmB S Protein of unknown function (DUF2584)
MDGJMAFB_02055 1.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MDGJMAFB_02056 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDGJMAFB_02057 0.0 asnB 6.3.5.4 E Asparagine synthase
MDGJMAFB_02058 1.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
MDGJMAFB_02059 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MDGJMAFB_02060 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
MDGJMAFB_02061 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MDGJMAFB_02062 9.7e-106 ytqB J Putative rRNA methylase
MDGJMAFB_02063 2.3e-189 yhcC S Fe-S oxidoreductase
MDGJMAFB_02064 6.7e-41 ytzC S Protein of unknown function (DUF2524)
MDGJMAFB_02066 5.1e-66 ytrA K GntR family transcriptional regulator
MDGJMAFB_02067 4.2e-161 ytrB P abc transporter atp-binding protein
MDGJMAFB_02068 1.5e-162 P ABC-2 family transporter protein
MDGJMAFB_02069 7e-149
MDGJMAFB_02070 7e-127 ytrE V ABC transporter, ATP-binding protein
MDGJMAFB_02071 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
MDGJMAFB_02072 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDGJMAFB_02073 8.9e-184 T PhoQ Sensor
MDGJMAFB_02074 1.1e-138 bceA V ABC transporter, ATP-binding protein
MDGJMAFB_02075 0.0 bceB V ABC transporter (permease)
MDGJMAFB_02076 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
MDGJMAFB_02077 8.6e-210 yttB EGP Major facilitator Superfamily
MDGJMAFB_02078 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MDGJMAFB_02079 7.7e-55 ytvB S Protein of unknown function (DUF4257)
MDGJMAFB_02080 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDGJMAFB_02081 2.1e-51 ytwF P Sulfurtransferase
MDGJMAFB_02082 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MDGJMAFB_02083 3.1e-142 amyC P ABC transporter (permease)
MDGJMAFB_02084 1.4e-167 amyD P ABC transporter
MDGJMAFB_02085 2.8e-246 msmE G Bacterial extracellular solute-binding protein
MDGJMAFB_02086 4.3e-189 msmR K Transcriptional regulator
MDGJMAFB_02087 4.1e-172 ytaP S Acetyl xylan esterase (AXE1)
MDGJMAFB_02088 4.4e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MDGJMAFB_02089 1.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MDGJMAFB_02090 7.9e-216 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MDGJMAFB_02091 1.2e-123 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MDGJMAFB_02092 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MDGJMAFB_02093 6.3e-221 bioI 1.14.14.46 C Cytochrome P450
MDGJMAFB_02094 1.4e-136 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
MDGJMAFB_02095 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
MDGJMAFB_02096 1.5e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
MDGJMAFB_02097 0.0 ytdP K Transcriptional regulator
MDGJMAFB_02098 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MDGJMAFB_02099 6.8e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MDGJMAFB_02100 1.5e-71 yteS G transport
MDGJMAFB_02101 8.3e-248 yteT S Oxidoreductase family, C-terminal alpha/beta domain
MDGJMAFB_02102 4.5e-115 yteU S Integral membrane protein
MDGJMAFB_02103 3.1e-26 yteV S Sporulation protein Cse60
MDGJMAFB_02104 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MDGJMAFB_02105 1.4e-231 ytfP S HI0933-like protein
MDGJMAFB_02106 4.7e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDGJMAFB_02107 6.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MDGJMAFB_02108 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MDGJMAFB_02109 4.8e-131 ythP V ABC transporter
MDGJMAFB_02110 4.2e-201 ythQ U Bacterial ABC transporter protein EcsB
MDGJMAFB_02111 2.1e-225 pbuO S permease
MDGJMAFB_02112 4.7e-268 pepV 3.5.1.18 E Dipeptidase
MDGJMAFB_02113 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MDGJMAFB_02114 5.6e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MDGJMAFB_02115 1.3e-165 ytlQ
MDGJMAFB_02116 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MDGJMAFB_02117 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MDGJMAFB_02118 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
MDGJMAFB_02119 2e-45 ytzH S YtzH-like protein
MDGJMAFB_02120 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDGJMAFB_02121 7.1e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MDGJMAFB_02122 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
MDGJMAFB_02123 1.1e-50 ytzB S small secreted protein
MDGJMAFB_02124 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MDGJMAFB_02125 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MDGJMAFB_02126 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MDGJMAFB_02127 9.8e-149 ytpQ S Belongs to the UPF0354 family
MDGJMAFB_02128 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDGJMAFB_02129 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MDGJMAFB_02130 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MDGJMAFB_02131 3.6e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDGJMAFB_02132 6.6e-17 ytxH S COG4980 Gas vesicle protein
MDGJMAFB_02133 3.1e-53 ytxJ O Protein of unknown function (DUF2847)
MDGJMAFB_02134 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MDGJMAFB_02135 1.7e-182 ccpA K catabolite control protein A
MDGJMAFB_02136 6e-146 motA N flagellar motor
MDGJMAFB_02137 1.4e-125 motS N Flagellar motor protein
MDGJMAFB_02138 3.5e-224 acuC BQ histone deacetylase
MDGJMAFB_02139 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
MDGJMAFB_02140 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MDGJMAFB_02141 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MDGJMAFB_02142 8e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDGJMAFB_02144 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDGJMAFB_02145 3.4e-308 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MDGJMAFB_02146 5.9e-88 ytsP 1.8.4.14 T GAF domain-containing protein
MDGJMAFB_02147 1e-108 yttP K Transcriptional regulator
MDGJMAFB_02148 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MDGJMAFB_02149 9.2e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MDGJMAFB_02150 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
MDGJMAFB_02151 1.2e-208 iscS2 2.8.1.7 E Cysteine desulfurase
MDGJMAFB_02152 3.9e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDGJMAFB_02153 2e-29 sspB S spore protein
MDGJMAFB_02154 5e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MDGJMAFB_02155 0.0 ytcJ S amidohydrolase
MDGJMAFB_02156 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDGJMAFB_02157 1.8e-179 sppA OU signal peptide peptidase SppA
MDGJMAFB_02158 2.5e-86 yteJ S RDD family
MDGJMAFB_02159 1.8e-114 ytfI S Protein of unknown function (DUF2953)
MDGJMAFB_02160 8.7e-70 ytfJ S Sporulation protein YtfJ
MDGJMAFB_02161 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MDGJMAFB_02162 5.4e-165 ytxK 2.1.1.72 L DNA methylase
MDGJMAFB_02163 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDGJMAFB_02164 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MDGJMAFB_02165 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MDGJMAFB_02166 3.4e-266 argH 4.3.2.1 E argininosuccinate lyase
MDGJMAFB_02168 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDGJMAFB_02169 1.7e-130 ytkL S Belongs to the UPF0173 family
MDGJMAFB_02170 3.6e-171 ytlI K LysR substrate binding domain
MDGJMAFB_02171 1.2e-99 ytmI K Acetyltransferase (GNAT) domain
MDGJMAFB_02172 1.1e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
MDGJMAFB_02173 3.2e-144 tcyK M Bacterial periplasmic substrate-binding proteins
MDGJMAFB_02174 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
MDGJMAFB_02175 1.9e-119 tcyM U Binding-protein-dependent transport system inner membrane component
MDGJMAFB_02176 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MDGJMAFB_02177 3.6e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDGJMAFB_02178 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
MDGJMAFB_02179 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDGJMAFB_02180 8.2e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
MDGJMAFB_02181 7.3e-236 ytnL 3.5.1.47 E hydrolase activity
MDGJMAFB_02182 3.4e-158 ytnM S membrane transporter protein
MDGJMAFB_02183 8e-241 ytoI K transcriptional regulator containing CBS domains
MDGJMAFB_02184 2.4e-47 ytpI S YtpI-like protein
MDGJMAFB_02185 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MDGJMAFB_02186 9.2e-29
MDGJMAFB_02187 2.4e-68 ytrI
MDGJMAFB_02188 3.2e-56 ytrH S Sporulation protein YtrH
MDGJMAFB_02189 0.0 dnaE 2.7.7.7 L DNA polymerase
MDGJMAFB_02190 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
MDGJMAFB_02191 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MDGJMAFB_02192 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MDGJMAFB_02193 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MDGJMAFB_02194 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MDGJMAFB_02195 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MDGJMAFB_02196 2.6e-192 ytvI S sporulation integral membrane protein YtvI
MDGJMAFB_02197 4.7e-71 yeaL S membrane
MDGJMAFB_02198 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
MDGJMAFB_02199 4.1e-242 icd 1.1.1.42 C isocitrate
MDGJMAFB_02200 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MDGJMAFB_02201 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDGJMAFB_02202 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MDGJMAFB_02203 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDGJMAFB_02204 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDGJMAFB_02205 9.5e-107 ytaF P Probably functions as a manganese efflux pump
MDGJMAFB_02206 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDGJMAFB_02207 8.9e-161 ytbE S reductase
MDGJMAFB_02208 1.7e-202 ytbD EGP Major facilitator Superfamily
MDGJMAFB_02209 9.9e-67 ytcD K Transcriptional regulator
MDGJMAFB_02210 6.3e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDGJMAFB_02211 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MDGJMAFB_02212 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDGJMAFB_02213 2.9e-265 dnaB L Membrane attachment protein
MDGJMAFB_02214 7.3e-172 dnaI L Primosomal protein DnaI
MDGJMAFB_02215 1.4e-110 ytxB S SNARE associated Golgi protein
MDGJMAFB_02216 1.4e-158 ytxC S YtxC-like family
MDGJMAFB_02218 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDGJMAFB_02219 4.7e-148 ysaA S HAD-hyrolase-like
MDGJMAFB_02220 0.0 lytS 2.7.13.3 T Histidine kinase
MDGJMAFB_02221 3.5e-129 lytT T COG3279 Response regulator of the LytR AlgR family
MDGJMAFB_02222 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MDGJMAFB_02223 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MDGJMAFB_02225 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDGJMAFB_02226 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MDGJMAFB_02227 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDGJMAFB_02228 1.7e-44 ysdA S Membrane
MDGJMAFB_02229 9.2e-68 ysdB S Sigma-w pathway protein YsdB
MDGJMAFB_02230 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
MDGJMAFB_02231 4.4e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MDGJMAFB_02232 5e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MDGJMAFB_02233 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
MDGJMAFB_02234 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MDGJMAFB_02235 7e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MDGJMAFB_02236 5.7e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MDGJMAFB_02237 6.2e-254 araN G carbohydrate transport
MDGJMAFB_02238 2.7e-166 araP G carbohydrate transport
MDGJMAFB_02239 2.2e-143 araQ G transport system permease
MDGJMAFB_02240 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
MDGJMAFB_02241 0.0 cstA T Carbon starvation protein
MDGJMAFB_02242 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
MDGJMAFB_02243 4.7e-257 glcF C Glycolate oxidase
MDGJMAFB_02244 3e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
MDGJMAFB_02245 7.7e-205 ysfB KT regulator
MDGJMAFB_02246 5.8e-32 sspI S Belongs to the SspI family
MDGJMAFB_02247 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDGJMAFB_02248 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDGJMAFB_02249 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDGJMAFB_02250 9e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDGJMAFB_02251 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MDGJMAFB_02252 1.3e-85 cvpA S membrane protein, required for colicin V production
MDGJMAFB_02253 0.0 polX L COG1796 DNA polymerase IV (family X)
MDGJMAFB_02254 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDGJMAFB_02255 7.3e-68 yshE S membrane
MDGJMAFB_02256 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MDGJMAFB_02257 2.7e-100 fadR K Transcriptional regulator
MDGJMAFB_02258 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MDGJMAFB_02259 1.2e-135 etfB C Electron transfer flavoprotein
MDGJMAFB_02260 1.2e-177 etfA C Electron transfer flavoprotein
MDGJMAFB_02261 2e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
MDGJMAFB_02262 2e-52 trxA O Belongs to the thioredoxin family
MDGJMAFB_02263 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDGJMAFB_02264 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MDGJMAFB_02265 1.2e-79 yslB S Protein of unknown function (DUF2507)
MDGJMAFB_02266 2.4e-107 sdhC C succinate dehydrogenase
MDGJMAFB_02267 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MDGJMAFB_02268 1.7e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MDGJMAFB_02269 1.9e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
MDGJMAFB_02270 3.3e-30 gerE K Transcriptional regulator
MDGJMAFB_02271 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
MDGJMAFB_02272 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MDGJMAFB_02273 8.5e-196 gerM S COG5401 Spore germination protein
MDGJMAFB_02274 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MDGJMAFB_02275 2.2e-102 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDGJMAFB_02276 4.1e-92 ysnB S Phosphoesterase
MDGJMAFB_02278 1.9e-128 ysnF S protein conserved in bacteria
MDGJMAFB_02279 2.9e-56 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MDGJMAFB_02280 1.8e-93 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MDGJMAFB_02281 6e-79 ysnE K acetyltransferase
MDGJMAFB_02283 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MDGJMAFB_02284 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
MDGJMAFB_02285 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MDGJMAFB_02286 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MDGJMAFB_02287 1.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MDGJMAFB_02288 1.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MDGJMAFB_02289 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MDGJMAFB_02290 8.6e-187 ysoA H Tetratricopeptide repeat
MDGJMAFB_02291 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDGJMAFB_02292 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDGJMAFB_02293 3.4e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MDGJMAFB_02294 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MDGJMAFB_02295 5.7e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MDGJMAFB_02296 1.4e-89 ysxD
MDGJMAFB_02297 5.9e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MDGJMAFB_02298 3.6e-146 hemX O cytochrome C
MDGJMAFB_02299 4.8e-171 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MDGJMAFB_02300 2.7e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MDGJMAFB_02301 3.6e-182 hemB 4.2.1.24 H Belongs to the ALAD family
MDGJMAFB_02302 5.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MDGJMAFB_02303 2e-199 spoVID M stage VI sporulation protein D
MDGJMAFB_02304 5e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MDGJMAFB_02305 1.6e-25
MDGJMAFB_02306 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDGJMAFB_02307 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MDGJMAFB_02308 3.3e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MDGJMAFB_02309 2.8e-161 spoIIB S Sporulation related domain
MDGJMAFB_02310 2.8e-102 maf D septum formation protein Maf
MDGJMAFB_02311 6.5e-125 radC E Belongs to the UPF0758 family
MDGJMAFB_02312 1.8e-184 mreB D Rod shape-determining protein MreB
MDGJMAFB_02313 1.1e-156 mreC M Involved in formation and maintenance of cell shape
MDGJMAFB_02314 1.4e-84 mreD M shape-determining protein
MDGJMAFB_02315 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MDGJMAFB_02316 4.7e-143 minD D Belongs to the ParA family
MDGJMAFB_02317 2.5e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MDGJMAFB_02318 9.2e-161 spoIVFB S Stage IV sporulation protein
MDGJMAFB_02319 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MDGJMAFB_02320 4.1e-56 ysxB J ribosomal protein
MDGJMAFB_02321 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MDGJMAFB_02322 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MDGJMAFB_02323 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDGJMAFB_02324 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
MDGJMAFB_02325 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
MDGJMAFB_02326 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
MDGJMAFB_02327 3.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
MDGJMAFB_02328 9.2e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MDGJMAFB_02329 2.7e-160 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MDGJMAFB_02330 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MDGJMAFB_02331 1.8e-156 safA M spore coat assembly protein SafA
MDGJMAFB_02332 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDGJMAFB_02333 3.6e-126 yebC K transcriptional regulatory protein
MDGJMAFB_02334 4.5e-261 alsT E Sodium alanine symporter
MDGJMAFB_02335 5.8e-50 S Family of unknown function (DUF5412)
MDGJMAFB_02337 6.5e-119 yrzF T serine threonine protein kinase
MDGJMAFB_02338 2.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MDGJMAFB_02339 5.3e-253 csbX EGP Major facilitator Superfamily
MDGJMAFB_02340 4.8e-93 bofC S BofC C-terminal domain
MDGJMAFB_02341 3.5e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDGJMAFB_02342 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDGJMAFB_02343 2.6e-18 yrzS S Protein of unknown function (DUF2905)
MDGJMAFB_02344 7.5e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MDGJMAFB_02345 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MDGJMAFB_02346 1.1e-38 yajC U Preprotein translocase subunit YajC
MDGJMAFB_02347 1.5e-74 yrzE S Protein of unknown function (DUF3792)
MDGJMAFB_02348 9.2e-113 yrbG S membrane
MDGJMAFB_02349 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDGJMAFB_02350 9.4e-49 yrzD S Post-transcriptional regulator
MDGJMAFB_02351 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MDGJMAFB_02352 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
MDGJMAFB_02353 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
MDGJMAFB_02354 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MDGJMAFB_02355 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDGJMAFB_02356 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDGJMAFB_02357 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDGJMAFB_02358 3.3e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
MDGJMAFB_02360 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
MDGJMAFB_02361 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MDGJMAFB_02362 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MDGJMAFB_02363 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MDGJMAFB_02364 1.2e-70 cymR K Transcriptional regulator
MDGJMAFB_02365 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
MDGJMAFB_02366 6.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MDGJMAFB_02367 1.4e-15 S COG0457 FOG TPR repeat
MDGJMAFB_02368 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDGJMAFB_02369 3.9e-81 yrrD S protein conserved in bacteria
MDGJMAFB_02370 9.8e-31 yrzR
MDGJMAFB_02371 8e-08 S Protein of unknown function (DUF3918)
MDGJMAFB_02372 7.6e-107 glnP P ABC transporter
MDGJMAFB_02373 1.8e-108 gluC P ABC transporter
MDGJMAFB_02374 4.8e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
MDGJMAFB_02375 6.4e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MDGJMAFB_02376 7.8e-170 yrrI S AI-2E family transporter
MDGJMAFB_02377 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDGJMAFB_02378 1.7e-41 yrzL S Belongs to the UPF0297 family
MDGJMAFB_02379 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDGJMAFB_02380 1.2e-45 yrzB S Belongs to the UPF0473 family
MDGJMAFB_02381 2.8e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MDGJMAFB_02382 2.1e-117 yrrM 2.1.1.104 S O-methyltransferase
MDGJMAFB_02383 3.9e-173 yegQ O Peptidase U32
MDGJMAFB_02384 2.7e-246 yegQ O COG0826 Collagenase and related proteases
MDGJMAFB_02385 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MDGJMAFB_02386 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDGJMAFB_02387 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
MDGJMAFB_02388 4.2e-63 yrrS S Protein of unknown function (DUF1510)
MDGJMAFB_02389 1e-25 yrzA S Protein of unknown function (DUF2536)
MDGJMAFB_02390 1.7e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MDGJMAFB_02391 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDGJMAFB_02392 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MDGJMAFB_02393 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MDGJMAFB_02394 4.6e-35 yrhC S YrhC-like protein
MDGJMAFB_02395 2.4e-78 yrhD S Protein of unknown function (DUF1641)
MDGJMAFB_02396 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MDGJMAFB_02397 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
MDGJMAFB_02398 4e-142 focA P Formate nitrite
MDGJMAFB_02401 1.4e-95 yrhH Q methyltransferase
MDGJMAFB_02402 1.8e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
MDGJMAFB_02403 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MDGJMAFB_02404 4.8e-45 yrhK S YrhK-like protein
MDGJMAFB_02405 0.0 yrhL I Acyltransferase family
MDGJMAFB_02406 4.7e-149 rsiV S Protein of unknown function (DUF3298)
MDGJMAFB_02407 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MDGJMAFB_02408 1.2e-149 yrhO K Archaeal transcriptional regulator TrmB
MDGJMAFB_02409 1.1e-105 yrhP E LysE type translocator
MDGJMAFB_02410 1.6e-252 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MDGJMAFB_02411 0.0 levR K PTS system fructose IIA component
MDGJMAFB_02412 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
MDGJMAFB_02413 2.4e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
MDGJMAFB_02414 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MDGJMAFB_02415 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MDGJMAFB_02416 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MDGJMAFB_02417 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
MDGJMAFB_02418 9.3e-200 adhA 1.1.1.1 C alcohol dehydrogenase
MDGJMAFB_02419 2.8e-46 yraB K helix_turn_helix, mercury resistance
MDGJMAFB_02420 1.1e-49 yraD M Spore coat protein
MDGJMAFB_02421 7.5e-26 yraE
MDGJMAFB_02422 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MDGJMAFB_02423 6.4e-63 yraF M Spore coat protein
MDGJMAFB_02424 1.5e-36 yraG
MDGJMAFB_02425 2.5e-65 E Glyoxalase-like domain
MDGJMAFB_02426 5.4e-61 T sh3 domain protein
MDGJMAFB_02427 4.9e-60 T sh3 domain protein
MDGJMAFB_02428 2.5e-152 S Alpha beta hydrolase
MDGJMAFB_02429 9.8e-21 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDGJMAFB_02430 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MDGJMAFB_02431 3.5e-205 yraM S PrpF protein
MDGJMAFB_02432 1.2e-163 yraN K Transcriptional regulator
MDGJMAFB_02433 2.8e-225 yraO C Citrate transporter
MDGJMAFB_02434 4.5e-188 yrpG C Aldo/keto reductase family
MDGJMAFB_02435 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
MDGJMAFB_02436 1.7e-115 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MDGJMAFB_02438 4.8e-123 yrpD S Domain of unknown function, YrpD
MDGJMAFB_02439 9.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MDGJMAFB_02440 6.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MDGJMAFB_02441 3.5e-165 aadK G Streptomycin adenylyltransferase
MDGJMAFB_02442 3.2e-89 yrdA S DinB family
MDGJMAFB_02443 4.4e-54 S Protein of unknown function (DUF2568)
MDGJMAFB_02444 2.5e-98 yrdC 3.5.1.19 Q Isochorismatase family
MDGJMAFB_02446 1.2e-227 cypA C Cytochrome P450
MDGJMAFB_02447 3.5e-45 yrdF K ribonuclease inhibitor
MDGJMAFB_02448 6.3e-79 bkdR K helix_turn_helix ASNC type
MDGJMAFB_02449 9.6e-138 azlC E AzlC protein
MDGJMAFB_02450 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
MDGJMAFB_02451 2.7e-228 brnQ E Component of the transport system for branched-chain amino acids
MDGJMAFB_02452 5e-162 gltR K LysR substrate binding domain
MDGJMAFB_02453 1.3e-66 yodA S tautomerase
MDGJMAFB_02454 2e-148 czcD P COG1230 Co Zn Cd efflux system component
MDGJMAFB_02455 1.5e-197 trkA P Oxidoreductase
MDGJMAFB_02456 8.6e-159 yrdQ K Transcriptional regulator
MDGJMAFB_02457 1.4e-170 yrdR EG EamA-like transporter family
MDGJMAFB_02458 3.9e-16 S YrzO-like protein
MDGJMAFB_02459 2.5e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MDGJMAFB_02460 1.4e-83 bltD 2.3.1.57 K FR47-like protein
MDGJMAFB_02461 1.5e-209 blt EGP Major facilitator Superfamily
MDGJMAFB_02462 6.9e-150 bltR K helix_turn_helix, mercury resistance
MDGJMAFB_02463 1.4e-106 yrkC G Cupin domain
MDGJMAFB_02464 7.8e-39 yrkD S protein conserved in bacteria
MDGJMAFB_02465 2.8e-82 yrkE O DsrE/DsrF/DrsH-like family
MDGJMAFB_02466 1.6e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
MDGJMAFB_02467 3.9e-204 yrkH P Rhodanese Homology Domain
MDGJMAFB_02468 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
MDGJMAFB_02469 2.6e-114 yrkJ S membrane transporter protein
MDGJMAFB_02470 6e-165 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MDGJMAFB_02471 1.1e-216 mepA V Multidrug transporter MatE
MDGJMAFB_02472 4.3e-113 tetR3 K Transcriptional regulator
MDGJMAFB_02473 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDGJMAFB_02474 6.6e-98 yqaB E IrrE N-terminal-like domain
MDGJMAFB_02476 1.3e-96 adk 2.7.4.3 F adenylate kinase activity
MDGJMAFB_02477 2e-89 K Transcriptional regulator PadR-like family
MDGJMAFB_02478 2.2e-159 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
MDGJMAFB_02480 1.3e-38 xkdC L IstB-like ATP binding protein
MDGJMAFB_02483 1.9e-40 L Transposase
MDGJMAFB_02484 3.7e-26 cotD S Inner spore coat protein D
MDGJMAFB_02486 8.6e-73 yqaS L DNA packaging
MDGJMAFB_02487 1.3e-27 S phage terminase, large subunit
MDGJMAFB_02488 9e-133 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MDGJMAFB_02489 1.2e-118 EGP Necrosis inducing protein (NPP1)
MDGJMAFB_02490 1.8e-83 S SMI1-KNR4 cell-wall
MDGJMAFB_02491 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MDGJMAFB_02493 4.4e-155 S Aspartate phosphatase response regulator
MDGJMAFB_02496 1.6e-54 arsR K ArsR family transcriptional regulator
MDGJMAFB_02497 5.7e-66 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDGJMAFB_02498 8.7e-182 arsB 1.20.4.1 P Arsenic resistance protein
MDGJMAFB_02499 4e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
MDGJMAFB_02500 1.3e-22 L Helix-turn-helix domain of resolvase
MDGJMAFB_02501 6e-140 yhfP 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
MDGJMAFB_02502 7.1e-64 K BetI-type transcriptional repressor, C-terminal
MDGJMAFB_02503 1.2e-277 cisA2 L Recombinase
MDGJMAFB_02504 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDGJMAFB_02505 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
MDGJMAFB_02506 2.3e-133 yqeB
MDGJMAFB_02507 2.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MDGJMAFB_02508 1.5e-104 yqeD S SNARE associated Golgi protein
MDGJMAFB_02509 2e-132 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MDGJMAFB_02510 1.8e-141 yqeF E GDSL-like Lipase/Acylhydrolase
MDGJMAFB_02512 5.3e-95 yqeG S hydrolase of the HAD superfamily
MDGJMAFB_02513 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MDGJMAFB_02514 3.9e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MDGJMAFB_02515 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MDGJMAFB_02516 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDGJMAFB_02517 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MDGJMAFB_02518 9.9e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDGJMAFB_02519 2.9e-139 yqeM Q Methyltransferase
MDGJMAFB_02520 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDGJMAFB_02521 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
MDGJMAFB_02522 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
MDGJMAFB_02523 0.0 comEC S Competence protein ComEC
MDGJMAFB_02524 4.1e-15 S YqzM-like protein
MDGJMAFB_02525 6.2e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
MDGJMAFB_02526 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
MDGJMAFB_02527 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MDGJMAFB_02528 1.5e-222 spoIIP M stage II sporulation protein P
MDGJMAFB_02529 7.2e-53 yqxA S Protein of unknown function (DUF3679)
MDGJMAFB_02530 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDGJMAFB_02531 2.6e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
MDGJMAFB_02532 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDGJMAFB_02533 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDGJMAFB_02534 0.0 dnaK O Heat shock 70 kDa protein
MDGJMAFB_02535 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDGJMAFB_02536 4.6e-174 prmA J Methylates ribosomal protein L11
MDGJMAFB_02537 2.1e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MDGJMAFB_02538 6.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MDGJMAFB_02539 2.9e-157 yqeW P COG1283 Na phosphate symporter
MDGJMAFB_02540 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MDGJMAFB_02541 2.5e-61 yqeY S Yqey-like protein
MDGJMAFB_02542 2.7e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MDGJMAFB_02543 4.3e-122 yqfA S UPF0365 protein
MDGJMAFB_02544 3.7e-22 yqfB
MDGJMAFB_02545 2.7e-45 yqfC S sporulation protein YqfC
MDGJMAFB_02546 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MDGJMAFB_02547 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
MDGJMAFB_02549 0.0 yqfF S membrane-associated HD superfamily hydrolase
MDGJMAFB_02550 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDGJMAFB_02551 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MDGJMAFB_02552 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MDGJMAFB_02553 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDGJMAFB_02554 8.4e-19 S YqzL-like protein
MDGJMAFB_02555 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
MDGJMAFB_02556 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MDGJMAFB_02557 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MDGJMAFB_02558 4.5e-112 ccpN K CBS domain
MDGJMAFB_02559 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MDGJMAFB_02560 4.5e-88 yaiI S Belongs to the UPF0178 family
MDGJMAFB_02561 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDGJMAFB_02562 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDGJMAFB_02563 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
MDGJMAFB_02564 1.4e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
MDGJMAFB_02565 1.2e-208 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MDGJMAFB_02566 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MDGJMAFB_02567 3.6e-12 yqfQ S YqfQ-like protein
MDGJMAFB_02568 2.9e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDGJMAFB_02569 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MDGJMAFB_02570 2.1e-36 yqfT S Protein of unknown function (DUF2624)
MDGJMAFB_02571 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MDGJMAFB_02572 4.2e-77 zur P Belongs to the Fur family
MDGJMAFB_02573 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MDGJMAFB_02574 2.8e-61 yqfX S membrane
MDGJMAFB_02575 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MDGJMAFB_02576 5.2e-47 yqfZ M LysM domain
MDGJMAFB_02577 2.5e-74 yqgA
MDGJMAFB_02578 1.9e-133 yqgB S Protein of unknown function (DUF1189)
MDGJMAFB_02579 5.2e-73 yqgC S protein conserved in bacteria
MDGJMAFB_02580 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MDGJMAFB_02581 2.5e-231 yqgE EGP Major facilitator superfamily
MDGJMAFB_02582 0.0 pbpA 3.4.16.4 M penicillin-binding protein
MDGJMAFB_02583 2.6e-150 pstS P Phosphate
MDGJMAFB_02584 5.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
MDGJMAFB_02585 4.4e-158 pstA P Phosphate transport system permease
MDGJMAFB_02586 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDGJMAFB_02587 8.3e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDGJMAFB_02588 7.3e-72 yqzC S YceG-like family
MDGJMAFB_02589 9.2e-51 yqzD
MDGJMAFB_02591 1.3e-196 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
MDGJMAFB_02592 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MDGJMAFB_02593 1.4e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDGJMAFB_02594 2.5e-09 yqgO
MDGJMAFB_02595 8.9e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MDGJMAFB_02596 3.1e-33 yqgQ S Protein conserved in bacteria
MDGJMAFB_02597 3.4e-180 glcK 2.7.1.2 G Glucokinase
MDGJMAFB_02598 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MDGJMAFB_02599 2.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
MDGJMAFB_02600 2.2e-196 yqgU
MDGJMAFB_02601 6.9e-50 yqgV S Thiamine-binding protein
MDGJMAFB_02602 8.9e-23 yqgW S Protein of unknown function (DUF2759)
MDGJMAFB_02603 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MDGJMAFB_02604 1.8e-37 yqgY S Protein of unknown function (DUF2626)
MDGJMAFB_02605 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
MDGJMAFB_02607 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDGJMAFB_02608 1.7e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MDGJMAFB_02609 7.2e-175 corA P Mg2 transporter protein
MDGJMAFB_02612 1.9e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MDGJMAFB_02613 3.6e-172 comGB NU COG1459 Type II secretory pathway, component PulF
MDGJMAFB_02614 6.8e-47 comGC U Required for transformation and DNA binding
MDGJMAFB_02615 1.2e-68 gspH NU protein transport across the cell outer membrane
MDGJMAFB_02616 2.2e-57 comGE
MDGJMAFB_02617 2e-35 comGF U Putative Competence protein ComGF
MDGJMAFB_02618 8.8e-44 S ComG operon protein 7
MDGJMAFB_02619 5.2e-26 yqzE S YqzE-like protein
MDGJMAFB_02620 7.3e-54 yqzG S Protein of unknown function (DUF3889)
MDGJMAFB_02621 1.3e-113 yqxM
MDGJMAFB_02622 2.1e-57 sipW 3.4.21.89 U Signal peptidase
MDGJMAFB_02623 3.6e-140 tasA S Cell division protein FtsN
MDGJMAFB_02624 1e-54 sinR K transcriptional
MDGJMAFB_02625 1.2e-24 sinI S Anti-repressor SinI
MDGJMAFB_02626 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
MDGJMAFB_02627 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MDGJMAFB_02628 2.4e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MDGJMAFB_02629 3.2e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MDGJMAFB_02630 2.6e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MDGJMAFB_02631 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
MDGJMAFB_02632 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MDGJMAFB_02633 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MDGJMAFB_02634 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
MDGJMAFB_02635 2.2e-61 yqhP
MDGJMAFB_02636 9.8e-172 yqhQ S Protein of unknown function (DUF1385)
MDGJMAFB_02637 2.3e-93 yqhR S Conserved membrane protein YqhR
MDGJMAFB_02638 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MDGJMAFB_02639 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MDGJMAFB_02640 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDGJMAFB_02641 7.9e-37 yqhV S Protein of unknown function (DUF2619)
MDGJMAFB_02642 2.3e-170 spoIIIAA S stage III sporulation protein AA
MDGJMAFB_02643 1.1e-84 spoIIIAB S Stage III sporulation protein
MDGJMAFB_02644 7.6e-29 spoIIIAC S stage III sporulation protein AC
MDGJMAFB_02645 2.3e-58 spoIIIAD S Stage III sporulation protein AD
MDGJMAFB_02646 1.3e-197 spoIIIAE S stage III sporulation protein AE
MDGJMAFB_02647 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MDGJMAFB_02648 3.4e-102 spoIIIAG S stage III sporulation protein AG
MDGJMAFB_02649 9.9e-91 spoIIIAH S SpoIIIAH-like protein
MDGJMAFB_02650 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MDGJMAFB_02651 5.9e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MDGJMAFB_02652 2.1e-67 yqhY S protein conserved in bacteria
MDGJMAFB_02653 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDGJMAFB_02654 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDGJMAFB_02655 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDGJMAFB_02656 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDGJMAFB_02657 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MDGJMAFB_02658 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDGJMAFB_02659 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MDGJMAFB_02660 1.7e-78 argR K Regulates arginine biosynthesis genes
MDGJMAFB_02661 2.2e-310 recN L May be involved in recombinational repair of damaged DNA
MDGJMAFB_02662 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
MDGJMAFB_02663 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MDGJMAFB_02665 7.5e-211 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MDGJMAFB_02666 6e-27
MDGJMAFB_02667 1.2e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
MDGJMAFB_02668 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MDGJMAFB_02669 1.5e-217 mmgA 2.3.1.9 I Belongs to the thiolase family
MDGJMAFB_02670 1.7e-154 hbdA 1.1.1.157 I Dehydrogenase
MDGJMAFB_02671 6.3e-210 mmgC I acyl-CoA dehydrogenase
MDGJMAFB_02672 4.4e-208 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MDGJMAFB_02673 6.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MDGJMAFB_02674 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MDGJMAFB_02675 4.1e-34 yqzF S Protein of unknown function (DUF2627)
MDGJMAFB_02676 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
MDGJMAFB_02677 8.6e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
MDGJMAFB_02678 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MDGJMAFB_02679 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
MDGJMAFB_02680 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MDGJMAFB_02681 7.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDGJMAFB_02682 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MDGJMAFB_02683 4.4e-228 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDGJMAFB_02684 1.3e-151 bmrR K helix_turn_helix, mercury resistance
MDGJMAFB_02685 7.9e-208 norA EGP Major facilitator Superfamily
MDGJMAFB_02686 1.4e-164 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MDGJMAFB_02687 9.3e-77 yqiW S Belongs to the UPF0403 family
MDGJMAFB_02688 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
MDGJMAFB_02689 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
MDGJMAFB_02690 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MDGJMAFB_02691 7.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
MDGJMAFB_02692 1.4e-98 yqjB S protein conserved in bacteria
MDGJMAFB_02694 8.7e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
MDGJMAFB_02695 3.5e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MDGJMAFB_02696 1.4e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MDGJMAFB_02697 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
MDGJMAFB_02698 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDGJMAFB_02699 4.5e-24 yqzJ
MDGJMAFB_02700 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDGJMAFB_02701 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDGJMAFB_02702 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDGJMAFB_02703 1.1e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MDGJMAFB_02704 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MDGJMAFB_02705 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MDGJMAFB_02706 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MDGJMAFB_02707 0.0 rocB E arginine degradation protein
MDGJMAFB_02708 2.2e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDGJMAFB_02709 3.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
MDGJMAFB_02710 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MDGJMAFB_02711 6.4e-262 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MDGJMAFB_02712 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
MDGJMAFB_02713 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDGJMAFB_02715 2e-225 yqjV G Major Facilitator Superfamily
MDGJMAFB_02717 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDGJMAFB_02718 6.3e-49 S YolD-like protein
MDGJMAFB_02719 3.6e-87 yqjY K acetyltransferase
MDGJMAFB_02720 1.3e-57 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
MDGJMAFB_02721 3.7e-193 yqkA K GrpB protein
MDGJMAFB_02722 2.8e-54 yqkB S Belongs to the HesB IscA family
MDGJMAFB_02723 9.4e-39 yqkC S Protein of unknown function (DUF2552)
MDGJMAFB_02724 2.5e-172 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MDGJMAFB_02725 3.1e-12 yqkE S Protein of unknown function (DUF3886)
MDGJMAFB_02726 2.4e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MDGJMAFB_02728 2.6e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MDGJMAFB_02729 2.1e-221 yqxK 3.6.4.12 L DNA helicase
MDGJMAFB_02730 4.5e-58 ansR K Transcriptional regulator
MDGJMAFB_02731 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
MDGJMAFB_02732 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MDGJMAFB_02733 1.6e-234 mleN C Na H antiporter
MDGJMAFB_02734 5.5e-242 mleA 1.1.1.38 C malic enzyme
MDGJMAFB_02735 2.1e-29 yqkK
MDGJMAFB_02736 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MDGJMAFB_02737 2.4e-80 fur P Belongs to the Fur family
MDGJMAFB_02738 1.4e-36 S Protein of unknown function (DUF4227)
MDGJMAFB_02739 2.6e-166 xerD L recombinase XerD
MDGJMAFB_02740 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MDGJMAFB_02741 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MDGJMAFB_02742 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MDGJMAFB_02743 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MDGJMAFB_02744 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MDGJMAFB_02745 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDGJMAFB_02746 9.6e-112 spoVAA S Stage V sporulation protein AA
MDGJMAFB_02747 1e-67 spoVAB S Stage V sporulation protein AB
MDGJMAFB_02748 2.3e-78 spoVAC S stage V sporulation protein AC
MDGJMAFB_02749 9e-192 spoVAD I Stage V sporulation protein AD
MDGJMAFB_02750 2.2e-57 spoVAEB S stage V sporulation protein
MDGJMAFB_02751 1.4e-110 spoVAEA S stage V sporulation protein
MDGJMAFB_02752 1.4e-273 spoVAF EG Stage V sporulation protein AF
MDGJMAFB_02753 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MDGJMAFB_02754 2.8e-149 ypuA S Secreted protein
MDGJMAFB_02755 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDGJMAFB_02759 2.1e-06
MDGJMAFB_02760 1.9e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDGJMAFB_02762 7e-16 S SNARE associated Golgi protein
MDGJMAFB_02763 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
MDGJMAFB_02764 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MDGJMAFB_02765 7.8e-55 ypuD
MDGJMAFB_02766 6.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MDGJMAFB_02767 1.3e-114 ribE 2.5.1.9 H Riboflavin synthase
MDGJMAFB_02768 1.4e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MDGJMAFB_02769 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MDGJMAFB_02770 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDGJMAFB_02771 1.6e-91 ypuF S Domain of unknown function (DUF309)
MDGJMAFB_02772 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDGJMAFB_02773 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDGJMAFB_02774 7.6e-97 ypuI S Protein of unknown function (DUF3907)
MDGJMAFB_02775 1.8e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MDGJMAFB_02776 3.5e-103 spmA S Spore maturation protein
MDGJMAFB_02777 1.9e-87 spmB S Spore maturation protein
MDGJMAFB_02778 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MDGJMAFB_02779 1.4e-98 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MDGJMAFB_02780 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MDGJMAFB_02781 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MDGJMAFB_02782 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDGJMAFB_02783 0.0 resE 2.7.13.3 T Histidine kinase
MDGJMAFB_02784 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
MDGJMAFB_02785 6.3e-199 rsiX
MDGJMAFB_02786 1e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MDGJMAFB_02787 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDGJMAFB_02788 2.7e-84 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDGJMAFB_02789 4.7e-41 fer C Ferredoxin
MDGJMAFB_02790 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
MDGJMAFB_02791 9.2e-286 recQ 3.6.4.12 L DNA helicase
MDGJMAFB_02792 1.1e-99 ypbD S metal-dependent membrane protease
MDGJMAFB_02793 1.3e-75 ypbE M Lysin motif
MDGJMAFB_02794 2.8e-81 ypbF S Protein of unknown function (DUF2663)
MDGJMAFB_02795 3e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
MDGJMAFB_02796 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MDGJMAFB_02797 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MDGJMAFB_02798 1.1e-173 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MDGJMAFB_02799 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
MDGJMAFB_02800 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MDGJMAFB_02801 2.5e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MDGJMAFB_02802 9.2e-113 ypfA M Flagellar protein YcgR
MDGJMAFB_02803 1.8e-23 S Family of unknown function (DUF5359)
MDGJMAFB_02804 4e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MDGJMAFB_02805 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
MDGJMAFB_02806 3.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDGJMAFB_02807 1.4e-07 S YpzI-like protein
MDGJMAFB_02808 1.9e-101 yphA
MDGJMAFB_02809 9.5e-161 seaA S YIEGIA protein
MDGJMAFB_02810 7.9e-28 ypzH
MDGJMAFB_02811 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MDGJMAFB_02812 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MDGJMAFB_02813 1.6e-18 yphE S Protein of unknown function (DUF2768)
MDGJMAFB_02814 6.6e-136 yphF
MDGJMAFB_02815 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MDGJMAFB_02816 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDGJMAFB_02817 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
MDGJMAFB_02818 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MDGJMAFB_02819 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MDGJMAFB_02820 4.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MDGJMAFB_02821 9.9e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MDGJMAFB_02822 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MDGJMAFB_02823 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MDGJMAFB_02824 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MDGJMAFB_02825 1.3e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MDGJMAFB_02826 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MDGJMAFB_02827 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MDGJMAFB_02828 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MDGJMAFB_02829 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MDGJMAFB_02830 1e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MDGJMAFB_02831 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MDGJMAFB_02832 4.7e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MDGJMAFB_02833 2.1e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MDGJMAFB_02834 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MDGJMAFB_02835 6.4e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MDGJMAFB_02836 7.7e-233 S COG0457 FOG TPR repeat
MDGJMAFB_02837 2.8e-99 ypiB S Belongs to the UPF0302 family
MDGJMAFB_02838 6.1e-76 ypiF S Protein of unknown function (DUF2487)
MDGJMAFB_02839 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
MDGJMAFB_02840 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
MDGJMAFB_02841 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MDGJMAFB_02842 4.4e-98 ypjA S membrane
MDGJMAFB_02843 6.1e-143 ypjB S sporulation protein
MDGJMAFB_02844 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MDGJMAFB_02845 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MDGJMAFB_02846 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MDGJMAFB_02847 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MDGJMAFB_02848 7.6e-129 bshB1 S proteins, LmbE homologs
MDGJMAFB_02849 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MDGJMAFB_02850 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDGJMAFB_02851 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MDGJMAFB_02852 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MDGJMAFB_02853 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MDGJMAFB_02854 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MDGJMAFB_02855 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MDGJMAFB_02856 4.1e-22 ypmA S Protein of unknown function (DUF4264)
MDGJMAFB_02857 2.2e-79 ypmB S protein conserved in bacteria
MDGJMAFB_02858 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MDGJMAFB_02859 1.3e-251 asnS 6.1.1.22 J asparaginyl-tRNA
MDGJMAFB_02860 5.7e-129 dnaD L DNA replication protein DnaD
MDGJMAFB_02861 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDGJMAFB_02862 4.7e-93 ypoC
MDGJMAFB_02863 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
MDGJMAFB_02864 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDGJMAFB_02865 7e-186 yppC S Protein of unknown function (DUF2515)
MDGJMAFB_02868 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
MDGJMAFB_02870 1.2e-48 yppG S YppG-like protein
MDGJMAFB_02871 3.3e-71 hspX O Belongs to the small heat shock protein (HSP20) family
MDGJMAFB_02872 1e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MDGJMAFB_02873 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MDGJMAFB_02874 7.3e-236 yprB L RNase_H superfamily
MDGJMAFB_02875 2.8e-91 ypsA S Belongs to the UPF0398 family
MDGJMAFB_02876 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDGJMAFB_02877 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MDGJMAFB_02879 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
MDGJMAFB_02880 8.7e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDGJMAFB_02881 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MDGJMAFB_02882 4.1e-184 ptxS K transcriptional
MDGJMAFB_02883 6.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MDGJMAFB_02884 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MDGJMAFB_02885 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MDGJMAFB_02886 4.6e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MDGJMAFB_02887 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDGJMAFB_02888 1.5e-226 pbuX F xanthine
MDGJMAFB_02889 2.5e-203 bcsA Q Naringenin-chalcone synthase
MDGJMAFB_02890 5.1e-87 ypbQ S protein conserved in bacteria
MDGJMAFB_02891 0.0 ypbR S Dynamin family
MDGJMAFB_02892 1e-38 ypbS S Protein of unknown function (DUF2533)
MDGJMAFB_02893 2e-07
MDGJMAFB_02894 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
MDGJMAFB_02896 4.6e-67 rnhA 3.1.26.4 L Ribonuclease
MDGJMAFB_02897 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MDGJMAFB_02898 4.4e-126 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
MDGJMAFB_02899 2.6e-27 ypeQ S Zinc-finger
MDGJMAFB_02900 8.1e-31 S Protein of unknown function (DUF2564)
MDGJMAFB_02901 3.8e-16 degR
MDGJMAFB_02902 7.9e-31 cspD K Cold-shock protein
MDGJMAFB_02903 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MDGJMAFB_02904 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MDGJMAFB_02905 1.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MDGJMAFB_02906 2.1e-106 ypgQ S phosphohydrolase
MDGJMAFB_02907 1.5e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
MDGJMAFB_02908 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MDGJMAFB_02909 1.7e-75 yphP S Belongs to the UPF0403 family
MDGJMAFB_02910 1.3e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
MDGJMAFB_02911 7.8e-114 ypjP S YpjP-like protein
MDGJMAFB_02912 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MDGJMAFB_02913 2.1e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDGJMAFB_02914 5.1e-95 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MDGJMAFB_02915 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MDGJMAFB_02916 4.2e-110 hlyIII S protein, Hemolysin III
MDGJMAFB_02917 6.1e-185 pspF K Transcriptional regulator
MDGJMAFB_02918 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MDGJMAFB_02919 3.1e-40 ypmP S Protein of unknown function (DUF2535)
MDGJMAFB_02920 2.2e-105 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MDGJMAFB_02921 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
MDGJMAFB_02922 1.1e-98 ypmS S protein conserved in bacteria
MDGJMAFB_02923 5.5e-29 ypmT S Uncharacterized ympT
MDGJMAFB_02924 2.7e-220 mepA V MATE efflux family protein
MDGJMAFB_02925 1.6e-70 ypoP K transcriptional
MDGJMAFB_02926 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDGJMAFB_02927 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MDGJMAFB_02928 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
MDGJMAFB_02929 7e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
MDGJMAFB_02930 2.2e-187 cgeB S Spore maturation protein
MDGJMAFB_02931 1.2e-65 cgeA
MDGJMAFB_02932 3.5e-38 cgeC
MDGJMAFB_02933 1.1e-255 cgeD M maturation of the outermost layer of the spore
MDGJMAFB_02934 1.8e-144 yiiD K acetyltransferase
MDGJMAFB_02937 3.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDGJMAFB_02938 9.3e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MDGJMAFB_02939 2.8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MDGJMAFB_02940 4.2e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
MDGJMAFB_02941 1.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
MDGJMAFB_02942 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
MDGJMAFB_02943 2.9e-47 yokU S YokU-like protein, putative antitoxin
MDGJMAFB_02944 1.4e-36 yozE S Belongs to the UPF0346 family
MDGJMAFB_02945 1.6e-123 yodN
MDGJMAFB_02947 2.8e-24 yozD S YozD-like protein
MDGJMAFB_02948 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
MDGJMAFB_02949 3.6e-54 yodL S YodL-like
MDGJMAFB_02950 5.3e-09
MDGJMAFB_02951 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MDGJMAFB_02952 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MDGJMAFB_02953 5.2e-24 yodI
MDGJMAFB_02954 1.1e-127 yodH Q Methyltransferase
MDGJMAFB_02955 2.8e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MDGJMAFB_02956 4.3e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDGJMAFB_02957 6.2e-28 S Protein of unknown function (DUF3311)
MDGJMAFB_02958 3.2e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
MDGJMAFB_02959 1.2e-111 mhqD S Carboxylesterase
MDGJMAFB_02960 1.4e-107 yodC C nitroreductase
MDGJMAFB_02961 4.4e-55 yodB K transcriptional
MDGJMAFB_02962 8e-64 yodA S tautomerase
MDGJMAFB_02963 2.7e-204 gntP EG COG2610 H gluconate symporter and related permeases
MDGJMAFB_02964 3.4e-09
MDGJMAFB_02965 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
MDGJMAFB_02966 5.6e-161 rarD S -transporter
MDGJMAFB_02967 1.5e-43
MDGJMAFB_02968 2.2e-60 yojF S Protein of unknown function (DUF1806)
MDGJMAFB_02969 2.1e-125 yojG S deacetylase
MDGJMAFB_02970 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDGJMAFB_02971 3e-243 norM V Multidrug efflux pump
MDGJMAFB_02973 7.6e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDGJMAFB_02974 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
MDGJMAFB_02975 2.5e-196 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MDGJMAFB_02976 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MDGJMAFB_02977 1.5e-161 yojN S ATPase family associated with various cellular activities (AAA)
MDGJMAFB_02978 0.0 yojO P Von Willebrand factor
MDGJMAFB_02979 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MDGJMAFB_02980 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MDGJMAFB_02981 1.1e-167 yocS S -transporter
MDGJMAFB_02982 4.5e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MDGJMAFB_02983 3.9e-164 sodA 1.15.1.1 P Superoxide dismutase
MDGJMAFB_02984 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
MDGJMAFB_02985 1.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MDGJMAFB_02986 2.7e-31 yozC
MDGJMAFB_02987 4.2e-56 yozO S Bacterial PH domain
MDGJMAFB_02988 1.9e-36 yocN
MDGJMAFB_02989 1.1e-40 yozN
MDGJMAFB_02990 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
MDGJMAFB_02991 2e-30
MDGJMAFB_02992 2.4e-53 yocL
MDGJMAFB_02993 2.2e-82 dksA T general stress protein
MDGJMAFB_02994 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MDGJMAFB_02995 0.0 recQ 3.6.4.12 L DNA helicase
MDGJMAFB_02996 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
MDGJMAFB_02997 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDGJMAFB_02998 2.1e-197 desK 2.7.13.3 T Histidine kinase
MDGJMAFB_02999 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MDGJMAFB_03000 1.9e-186 yocD 3.4.17.13 V peptidase S66
MDGJMAFB_03001 8e-93 yocC
MDGJMAFB_03002 6.4e-145
MDGJMAFB_03003 1.5e-92 yozB S membrane
MDGJMAFB_03004 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MDGJMAFB_03005 1e-51 czrA K transcriptional
MDGJMAFB_03006 3.3e-92 yobW
MDGJMAFB_03007 2.4e-175 yobV K WYL domain
MDGJMAFB_03008 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
MDGJMAFB_03009 4.7e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
MDGJMAFB_03010 3e-99 yobS K Transcriptional regulator
MDGJMAFB_03011 2.5e-143 yobR 2.3.1.1 J FR47-like protein
MDGJMAFB_03012 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
MDGJMAFB_03013 3.8e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
MDGJMAFB_03014 0.0 yobO M Pectate lyase superfamily protein
MDGJMAFB_03015 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
MDGJMAFB_03016 7.9e-105 yokH G SMI1 / KNR4 family
MDGJMAFB_03017 4.4e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MDGJMAFB_03018 6.9e-19
MDGJMAFB_03020 1.8e-95 S aspartate phosphatase
MDGJMAFB_03023 2.8e-33 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
MDGJMAFB_03025 2.5e-115 S DNA ligase (ATP) activity
MDGJMAFB_03026 1.3e-75 K SIR2-like domain
MDGJMAFB_03027 3.9e-36 S Putative zinc- or iron-chelating domain
MDGJMAFB_03028 2.5e-08 ywlA S Uncharacterised protein family (UPF0715)
MDGJMAFB_03029 1.3e-78 yoaW
MDGJMAFB_03030 9.4e-26 K Cro/C1-type HTH DNA-binding domain
MDGJMAFB_03031 2.4e-07
MDGJMAFB_03037 9.8e-11
MDGJMAFB_03038 1.7e-54 K Helix-turn-helix
MDGJMAFB_03039 8.8e-37 S TM2 domain
MDGJMAFB_03040 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
MDGJMAFB_03041 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MDGJMAFB_03045 8.5e-165 bla 3.5.2.6 V beta-lactamase
MDGJMAFB_03046 5.2e-113 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MDGJMAFB_03047 1.8e-77 yoaW
MDGJMAFB_03048 2.8e-157 yijE EG EamA-like transporter family
MDGJMAFB_03049 1.1e-158 yoaU K LysR substrate binding domain
MDGJMAFB_03050 4.3e-149 yoaT S Protein of unknown function (DUF817)
MDGJMAFB_03051 4.4e-30 yozG K Transcriptional regulator
MDGJMAFB_03052 2.8e-74 yoaS S Protein of unknown function (DUF2975)
MDGJMAFB_03053 7.1e-172 yoaR V vancomycin resistance protein
MDGJMAFB_03054 6.6e-87
MDGJMAFB_03056 1.4e-52 yoaQ S Evidence 4 Homologs of previously reported genes of
MDGJMAFB_03057 1e-144 yoaP 3.1.3.18 K YoaP-like
MDGJMAFB_03059 3e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
MDGJMAFB_03061 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
MDGJMAFB_03062 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
MDGJMAFB_03063 2.6e-110 yoaK S Membrane
MDGJMAFB_03064 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
MDGJMAFB_03065 9e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
MDGJMAFB_03066 1.7e-182 mcpU NT methyl-accepting chemotaxis protein
MDGJMAFB_03067 7.7e-35 S Protein of unknown function (DUF4025)
MDGJMAFB_03068 7.7e-13
MDGJMAFB_03069 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
MDGJMAFB_03070 1.9e-33 yoaF
MDGJMAFB_03071 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDGJMAFB_03072 4.7e-185 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDGJMAFB_03073 1.4e-278 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MDGJMAFB_03074 4.4e-233 yoaB EGP Major facilitator Superfamily
MDGJMAFB_03075 1.9e-126 3.1.1.3 I Lipase (class 3)
MDGJMAFB_03076 7.5e-242 S Arylsulfotransferase (ASST)
MDGJMAFB_03077 1.5e-92 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MDGJMAFB_03078 1.3e-94 yoxB
MDGJMAFB_03079 3.1e-24 yoxB
MDGJMAFB_03080 8.3e-40 yoxC S Bacterial protein of unknown function (DUF948)
MDGJMAFB_03081 2.4e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MDGJMAFB_03082 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MDGJMAFB_03083 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDGJMAFB_03084 6e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDGJMAFB_03085 7.8e-155 gltC K Transcriptional regulator
MDGJMAFB_03086 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MDGJMAFB_03087 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MDGJMAFB_03088 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MDGJMAFB_03089 2.5e-158 gltR1 K Transcriptional regulator
MDGJMAFB_03090 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MDGJMAFB_03091 5.1e-34 yoeD G Helix-turn-helix domain
MDGJMAFB_03092 6.5e-96 L Integrase
MDGJMAFB_03094 5.3e-98 yoeB S IseA DL-endopeptidase inhibitor
MDGJMAFB_03095 1.9e-245 yoeA V MATE efflux family protein
MDGJMAFB_03096 1.8e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
MDGJMAFB_03097 1e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MDGJMAFB_03098 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDGJMAFB_03099 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDGJMAFB_03100 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDGJMAFB_03101 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDGJMAFB_03102 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MDGJMAFB_03103 4e-63 yngL S Protein of unknown function (DUF1360)
MDGJMAFB_03104 5e-303 yngK T Glycosyl hydrolase-like 10
MDGJMAFB_03105 1.6e-11 K Bacterial regulatory proteins, tetR family
MDGJMAFB_03106 1.2e-27 S Family of unknown function (DUF5367)
MDGJMAFB_03107 8.3e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MDGJMAFB_03108 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MDGJMAFB_03109 5.6e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MDGJMAFB_03110 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MDGJMAFB_03111 3.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
MDGJMAFB_03112 9.2e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MDGJMAFB_03113 1.7e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MDGJMAFB_03114 2.5e-233 nrnB S phosphohydrolase (DHH superfamily)
MDGJMAFB_03115 5.5e-104 yngC S membrane-associated protein
MDGJMAFB_03116 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MDGJMAFB_03117 5e-78 yngA S membrane
MDGJMAFB_03118 1.2e-296 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
MDGJMAFB_03119 2.9e-248 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
MDGJMAFB_03121 1.9e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
MDGJMAFB_03122 9e-251 agcS E Sodium alanine symporter
MDGJMAFB_03123 5e-67 agcS E Sodium alanine symporter
MDGJMAFB_03124 1.3e-57 ynfC
MDGJMAFB_03125 2.3e-12
MDGJMAFB_03126 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDGJMAFB_03127 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDGJMAFB_03128 6.6e-69 yccU S CoA-binding protein
MDGJMAFB_03129 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDGJMAFB_03130 4.1e-49 yneR S Belongs to the HesB IscA family
MDGJMAFB_03131 2.9e-53 yneQ
MDGJMAFB_03132 1.2e-73 yneP S Thioesterase-like superfamily
MDGJMAFB_03133 3.9e-35 tlp S Belongs to the Tlp family
MDGJMAFB_03134 3.1e-08 sspN S Small acid-soluble spore protein N family
MDGJMAFB_03136 1e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MDGJMAFB_03137 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MDGJMAFB_03138 2.2e-14 sspO S Belongs to the SspO family
MDGJMAFB_03139 3.9e-19 sspP S Belongs to the SspP family
MDGJMAFB_03140 1.1e-62 hspX O Spore coat protein
MDGJMAFB_03141 2.1e-73 yneK S Protein of unknown function (DUF2621)
MDGJMAFB_03142 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MDGJMAFB_03143 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MDGJMAFB_03144 7.1e-127 ccdA O cytochrome c biogenesis protein
MDGJMAFB_03145 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
MDGJMAFB_03146 1.8e-28 yneF S UPF0154 protein
MDGJMAFB_03147 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
MDGJMAFB_03148 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MDGJMAFB_03149 1.3e-32 ynzC S UPF0291 protein
MDGJMAFB_03150 4.5e-112 yneB L resolvase
MDGJMAFB_03151 9.9e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MDGJMAFB_03152 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDGJMAFB_03153 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MDGJMAFB_03154 6.4e-73 yndM S Protein of unknown function (DUF2512)
MDGJMAFB_03155 4.7e-137 yndL S Replication protein
MDGJMAFB_03157 9.4e-308 yndJ S YndJ-like protein
MDGJMAFB_03158 6.4e-116 yndH S Domain of unknown function (DUF4166)
MDGJMAFB_03159 3e-150 yndG S DoxX-like family
MDGJMAFB_03160 6.1e-219 gerLC S Spore germination protein
MDGJMAFB_03161 1.7e-196 gerAB U Spore germination
MDGJMAFB_03162 4.6e-280 gerAA EG Spore germination protein
MDGJMAFB_03165 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
MDGJMAFB_03166 4.1e-71
MDGJMAFB_03167 7.9e-25 tatA U protein secretion
MDGJMAFB_03170 1.8e-125 S Domain of unknown function, YrpD
MDGJMAFB_03172 4e-161 S Thymidylate synthase
MDGJMAFB_03175 5.2e-15
MDGJMAFB_03176 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MDGJMAFB_03177 2e-82 yncE S Protein of unknown function (DUF2691)
MDGJMAFB_03178 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDGJMAFB_03179 5.5e-256 iolT EGP Major facilitator Superfamily
MDGJMAFB_03180 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
MDGJMAFB_03181 3.6e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
MDGJMAFB_03182 6.4e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MDGJMAFB_03183 3.4e-211 xylR GK ROK family
MDGJMAFB_03184 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MDGJMAFB_03185 2.7e-255 xynT G MFS/sugar transport protein
MDGJMAFB_03186 2.4e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
MDGJMAFB_03189 4.9e-111 ynaE S Domain of unknown function (DUF3885)
MDGJMAFB_03190 5e-15 K Cro/C1-type HTH DNA-binding domain
MDGJMAFB_03191 4.7e-08 S Uncharacterised protein family (UPF0715)
MDGJMAFB_03192 3.6e-75 S CAAX protease self-immunity
MDGJMAFB_03194 3.8e-96 ynaD J Acetyltransferase (GNAT) domain
MDGJMAFB_03196 1.9e-216 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
MDGJMAFB_03197 5e-196 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MDGJMAFB_03198 1.6e-112 H Methionine biosynthesis protein MetW
MDGJMAFB_03199 2.2e-93 M Glycosyltransferase like family
MDGJMAFB_03200 1.6e-69 Q Collagen triple helix repeat (20 copies)
MDGJMAFB_03201 3.9e-31
MDGJMAFB_03202 1.5e-09
MDGJMAFB_03203 7e-261 glnA 6.3.1.2 E glutamine synthetase
MDGJMAFB_03204 1.1e-68 glnR K transcriptional
MDGJMAFB_03205 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MDGJMAFB_03206 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDGJMAFB_03207 1.9e-175 spoVK O stage V sporulation protein K
MDGJMAFB_03208 2.8e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MDGJMAFB_03209 2.2e-108 ymaB
MDGJMAFB_03210 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDGJMAFB_03211 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDGJMAFB_03212 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MDGJMAFB_03213 4.5e-22 ymzA
MDGJMAFB_03214 8.2e-23
MDGJMAFB_03215 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MDGJMAFB_03216 4.6e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDGJMAFB_03217 2.1e-46 ymaF S YmaF family
MDGJMAFB_03219 1.2e-49 ebrA P Small Multidrug Resistance protein
MDGJMAFB_03220 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
MDGJMAFB_03221 1e-78 ymaD O redox protein, regulator of disulfide bond formation
MDGJMAFB_03222 7.8e-126 ymaC S Replication protein
MDGJMAFB_03223 1.9e-07 K Transcriptional regulator
MDGJMAFB_03224 5e-251 aprX O Belongs to the peptidase S8 family
MDGJMAFB_03225 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
MDGJMAFB_03226 4.4e-61 ymzB
MDGJMAFB_03227 2.2e-232 cypA C Cytochrome P450
MDGJMAFB_03228 0.0 pks13 HQ Beta-ketoacyl synthase
MDGJMAFB_03229 0.0 dhbF IQ polyketide synthase
MDGJMAFB_03230 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
MDGJMAFB_03231 0.0 pfaA Q Polyketide synthase of type I
MDGJMAFB_03232 0.0 rhiB IQ polyketide synthase
MDGJMAFB_03233 5.7e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
MDGJMAFB_03234 2.9e-142 pksH 4.2.1.18 I enoyl-CoA hydratase
MDGJMAFB_03235 8.7e-245 pksG 2.3.3.10 I synthase
MDGJMAFB_03236 5.1e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MDGJMAFB_03237 1.4e-37 acpK IQ Phosphopantetheine attachment site
MDGJMAFB_03238 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MDGJMAFB_03239 1.6e-182 pksD Q Acyl transferase domain
MDGJMAFB_03241 3.7e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MDGJMAFB_03242 2.8e-128 pksB 3.1.2.6 S Polyketide biosynthesis
MDGJMAFB_03243 1.3e-108 pksA K Transcriptional regulator
MDGJMAFB_03244 3.5e-97 ymcC S Membrane
MDGJMAFB_03245 3.4e-69 S Regulatory protein YrvL
MDGJMAFB_03246 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDGJMAFB_03247 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDGJMAFB_03248 2.2e-88 cotE S Spore coat protein
MDGJMAFB_03249 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MDGJMAFB_03250 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MDGJMAFB_03251 4.7e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MDGJMAFB_03252 2.8e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MDGJMAFB_03253 1.2e-36 spoVS S Stage V sporulation protein S
MDGJMAFB_03254 9.3e-152 ymdB S protein conserved in bacteria
MDGJMAFB_03255 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
MDGJMAFB_03256 2.6e-214 pbpX V Beta-lactamase
MDGJMAFB_03257 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDGJMAFB_03258 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
MDGJMAFB_03259 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDGJMAFB_03260 1.9e-124 ymfM S protein conserved in bacteria
MDGJMAFB_03261 2.7e-143 ymfK S Protein of unknown function (DUF3388)
MDGJMAFB_03262 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
MDGJMAFB_03263 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MDGJMAFB_03264 3.2e-242 ymfH S zinc protease
MDGJMAFB_03265 6e-233 ymfF S Peptidase M16
MDGJMAFB_03266 3.8e-205 ymfD EGP Major facilitator Superfamily
MDGJMAFB_03267 1.4e-133 ymfC K Transcriptional regulator
MDGJMAFB_03268 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MDGJMAFB_03269 1.7e-31 S YlzJ-like protein
MDGJMAFB_03270 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MDGJMAFB_03271 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDGJMAFB_03272 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDGJMAFB_03273 6.5e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MDGJMAFB_03274 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDGJMAFB_03275 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MDGJMAFB_03276 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MDGJMAFB_03277 2.6e-42 ymxH S YlmC YmxH family
MDGJMAFB_03278 2.8e-232 pepR S Belongs to the peptidase M16 family
MDGJMAFB_03279 4.4e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MDGJMAFB_03280 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MDGJMAFB_03281 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDGJMAFB_03282 3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MDGJMAFB_03283 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDGJMAFB_03284 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDGJMAFB_03285 3.9e-44 ylxP S protein conserved in bacteria
MDGJMAFB_03286 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDGJMAFB_03287 3.1e-47 ylxQ J ribosomal protein
MDGJMAFB_03288 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
MDGJMAFB_03289 1.1e-203 nusA K Participates in both transcription termination and antitermination
MDGJMAFB_03290 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
MDGJMAFB_03291 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDGJMAFB_03292 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDGJMAFB_03293 3.8e-232 rasP M zinc metalloprotease
MDGJMAFB_03294 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MDGJMAFB_03295 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
MDGJMAFB_03296 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDGJMAFB_03297 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDGJMAFB_03298 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MDGJMAFB_03299 8.2e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDGJMAFB_03300 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
MDGJMAFB_03301 3.1e-76 ylxL
MDGJMAFB_03302 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDGJMAFB_03303 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MDGJMAFB_03304 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MDGJMAFB_03305 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
MDGJMAFB_03306 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MDGJMAFB_03307 2.4e-195 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MDGJMAFB_03308 2.2e-157 flhG D Belongs to the ParA family
MDGJMAFB_03309 2.6e-200 flhF N Flagellar biosynthesis regulator FlhF
MDGJMAFB_03310 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MDGJMAFB_03311 4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MDGJMAFB_03312 3.6e-132 fliR N Flagellar biosynthetic protein FliR
MDGJMAFB_03313 2.4e-35 fliQ N Role in flagellar biosynthesis
MDGJMAFB_03314 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
MDGJMAFB_03315 7.9e-96 fliZ N Flagellar biosynthesis protein, FliO
MDGJMAFB_03316 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
MDGJMAFB_03317 6.6e-183 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MDGJMAFB_03318 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MDGJMAFB_03319 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
MDGJMAFB_03320 8.2e-140 flgG N Flagellar basal body rod
MDGJMAFB_03321 1.7e-72 flgD N Flagellar basal body rod modification protein
MDGJMAFB_03322 1.2e-216 fliK N Flagellar hook-length control protein
MDGJMAFB_03323 1.1e-35 ylxF S MgtE intracellular N domain
MDGJMAFB_03324 1.5e-69 fliJ N Flagellar biosynthesis chaperone
MDGJMAFB_03325 4.7e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MDGJMAFB_03326 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MDGJMAFB_03327 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MDGJMAFB_03328 2.6e-254 fliF N The M ring may be actively involved in energy transduction
MDGJMAFB_03329 1.9e-31 fliE N Flagellar hook-basal body
MDGJMAFB_03330 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
MDGJMAFB_03331 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MDGJMAFB_03332 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MDGJMAFB_03333 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MDGJMAFB_03334 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MDGJMAFB_03335 2.5e-169 xerC L tyrosine recombinase XerC
MDGJMAFB_03336 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MDGJMAFB_03337 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDGJMAFB_03338 3.2e-169 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MDGJMAFB_03339 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MDGJMAFB_03340 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MDGJMAFB_03341 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MDGJMAFB_03342 6.9e-285 ylqG
MDGJMAFB_03343 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDGJMAFB_03344 1.2e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDGJMAFB_03345 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDGJMAFB_03346 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MDGJMAFB_03347 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDGJMAFB_03348 3.1e-60 ylqD S YlqD protein
MDGJMAFB_03349 4.5e-36 ylqC S Belongs to the UPF0109 family
MDGJMAFB_03350 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MDGJMAFB_03351 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDGJMAFB_03352 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDGJMAFB_03353 2.9e-87
MDGJMAFB_03354 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDGJMAFB_03355 0.0 smc D Required for chromosome condensation and partitioning
MDGJMAFB_03356 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDGJMAFB_03357 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDGJMAFB_03358 6.1e-129 IQ reductase
MDGJMAFB_03359 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MDGJMAFB_03360 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MDGJMAFB_03361 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MDGJMAFB_03362 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDGJMAFB_03363 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
MDGJMAFB_03364 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MDGJMAFB_03365 1.4e-298 yloV S kinase related to dihydroxyacetone kinase
MDGJMAFB_03366 5.5e-59 asp S protein conserved in bacteria
MDGJMAFB_03367 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MDGJMAFB_03368 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
MDGJMAFB_03369 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MDGJMAFB_03370 1.9e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDGJMAFB_03371 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MDGJMAFB_03372 1.6e-140 stp 3.1.3.16 T phosphatase
MDGJMAFB_03373 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MDGJMAFB_03374 4.6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDGJMAFB_03375 1.1e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDGJMAFB_03376 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDGJMAFB_03377 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDGJMAFB_03378 8.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDGJMAFB_03379 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDGJMAFB_03380 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MDGJMAFB_03381 1.5e-40 ylzA S Belongs to the UPF0296 family
MDGJMAFB_03382 1.2e-155 yloC S stress-induced protein
MDGJMAFB_03383 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MDGJMAFB_03384 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MDGJMAFB_03385 8.2e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MDGJMAFB_03386 3.8e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MDGJMAFB_03387 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MDGJMAFB_03388 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MDGJMAFB_03389 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MDGJMAFB_03390 9.2e-179 cysP P phosphate transporter
MDGJMAFB_03391 1.6e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MDGJMAFB_03393 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDGJMAFB_03394 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDGJMAFB_03395 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDGJMAFB_03396 2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MDGJMAFB_03397 0.0 carB 6.3.5.5 F Belongs to the CarB family
MDGJMAFB_03398 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MDGJMAFB_03399 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDGJMAFB_03400 8.5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MDGJMAFB_03401 2.6e-231 pyrP F Xanthine uracil
MDGJMAFB_03402 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDGJMAFB_03403 3.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDGJMAFB_03404 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDGJMAFB_03405 3.8e-63 dksA T COG1734 DnaK suppressor protein
MDGJMAFB_03406 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDGJMAFB_03407 2.6e-67 divIVA D Cell division initiation protein
MDGJMAFB_03408 8.2e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MDGJMAFB_03409 1.6e-39 yggT S membrane
MDGJMAFB_03410 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDGJMAFB_03411 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MDGJMAFB_03412 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MDGJMAFB_03413 2.4e-37 ylmC S sporulation protein
MDGJMAFB_03414 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
MDGJMAFB_03415 1.5e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MDGJMAFB_03416 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDGJMAFB_03417 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDGJMAFB_03418 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MDGJMAFB_03419 0.0 bpr O COG1404 Subtilisin-like serine proteases
MDGJMAFB_03420 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDGJMAFB_03421 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDGJMAFB_03422 6.2e-58 sbp S small basic protein
MDGJMAFB_03423 4e-91 ylxX S protein conserved in bacteria
MDGJMAFB_03424 4.1e-103 ylxW S protein conserved in bacteria
MDGJMAFB_03425 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDGJMAFB_03426 5.3e-167 murB 1.3.1.98 M cell wall formation
MDGJMAFB_03427 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDGJMAFB_03428 5.7e-186 spoVE D Belongs to the SEDS family
MDGJMAFB_03429 2.9e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDGJMAFB_03430 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDGJMAFB_03431 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDGJMAFB_03432 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MDGJMAFB_03433 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MDGJMAFB_03434 3.7e-44 ftsL D Essential cell division protein
MDGJMAFB_03435 2.1e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDGJMAFB_03436 2.9e-78 mraZ K Belongs to the MraZ family
MDGJMAFB_03437 3.2e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MDGJMAFB_03438 1.6e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDGJMAFB_03439 2.6e-88 ylbP K n-acetyltransferase
MDGJMAFB_03440 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MDGJMAFB_03441 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MDGJMAFB_03442 2.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
MDGJMAFB_03444 4.8e-123 ylbM S Belongs to the UPF0348 family
MDGJMAFB_03445 9.8e-14 yqgA
MDGJMAFB_03446 9.7e-186 ylbL T Belongs to the peptidase S16 family
MDGJMAFB_03447 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
MDGJMAFB_03448 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
MDGJMAFB_03449 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDGJMAFB_03450 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
MDGJMAFB_03451 3.7e-38 ylbG S UPF0298 protein
MDGJMAFB_03452 1.8e-75 ylbF S Belongs to the UPF0342 family
MDGJMAFB_03453 2.5e-36 ylbE S YlbE-like protein
MDGJMAFB_03454 4.1e-63 ylbD S Putative coat protein
MDGJMAFB_03455 9.6e-200 ylbC S protein with SCP PR1 domains
MDGJMAFB_03456 7.5e-74 ylbB T COG0517 FOG CBS domain
MDGJMAFB_03457 3.5e-61 ylbA S YugN-like family
MDGJMAFB_03458 8.8e-167 ctaG S cytochrome c oxidase
MDGJMAFB_03459 2.3e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MDGJMAFB_03460 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MDGJMAFB_03461 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MDGJMAFB_03462 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MDGJMAFB_03463 4.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MDGJMAFB_03464 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MDGJMAFB_03465 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MDGJMAFB_03466 7.9e-211 ftsW D Belongs to the SEDS family
MDGJMAFB_03467 8.7e-44 ylaN S Belongs to the UPF0358 family
MDGJMAFB_03468 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
MDGJMAFB_03469 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MDGJMAFB_03470 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MDGJMAFB_03471 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDGJMAFB_03472 2.5e-32 ylaI S protein conserved in bacteria
MDGJMAFB_03473 4.2e-47 ylaH S YlaH-like protein
MDGJMAFB_03474 0.0 typA T GTP-binding protein TypA
MDGJMAFB_03475 4.1e-21 S Family of unknown function (DUF5325)
MDGJMAFB_03476 4.1e-38 ylaE
MDGJMAFB_03477 3.5e-11 sigC S Putative zinc-finger
MDGJMAFB_03478 1.3e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
MDGJMAFB_03479 6.6e-41 ylaB
MDGJMAFB_03480 0.0 ylaA
MDGJMAFB_03481 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
MDGJMAFB_03482 3.5e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MDGJMAFB_03483 2.4e-75 ykzC S Acetyltransferase (GNAT) family
MDGJMAFB_03484 1.1e-149 suhB 3.1.3.25 G Inositol monophosphatase
MDGJMAFB_03485 7.1e-26 ykzI
MDGJMAFB_03486 2.3e-116 yktB S Belongs to the UPF0637 family
MDGJMAFB_03487 1.6e-42 yktA S Belongs to the UPF0223 family
MDGJMAFB_03488 1e-273 speA 4.1.1.19 E Arginine
MDGJMAFB_03489 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
MDGJMAFB_03490 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MDGJMAFB_03491 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDGJMAFB_03492 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MDGJMAFB_03493 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDGJMAFB_03494 2e-115 recN L Putative cell-wall binding lipoprotein
MDGJMAFB_03496 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDGJMAFB_03497 5.5e-147 ykrA S hydrolases of the HAD superfamily
MDGJMAFB_03498 8.2e-31 ykzG S Belongs to the UPF0356 family
MDGJMAFB_03499 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDGJMAFB_03500 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MDGJMAFB_03501 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
MDGJMAFB_03502 1.2e-157 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
MDGJMAFB_03503 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MDGJMAFB_03504 1.5e-43 abrB K of stationary sporulation gene expression
MDGJMAFB_03505 7.7e-183 mreB D Rod-share determining protein MreBH
MDGJMAFB_03506 1.1e-12 S Uncharacterized protein YkpC
MDGJMAFB_03507 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MDGJMAFB_03508 2.6e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDGJMAFB_03509 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MDGJMAFB_03510 8.1e-39 ykoA
MDGJMAFB_03511 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MDGJMAFB_03512 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MDGJMAFB_03513 3.1e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MDGJMAFB_03514 3.1e-136 fruR K Transcriptional regulator
MDGJMAFB_03515 4.7e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
MDGJMAFB_03516 2.5e-124 macB V ABC transporter, ATP-binding protein
MDGJMAFB_03517 5.6e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MDGJMAFB_03518 1.6e-115 yknW S Yip1 domain
MDGJMAFB_03519 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
MDGJMAFB_03520 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
MDGJMAFB_03521 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MDGJMAFB_03522 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MDGJMAFB_03523 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MDGJMAFB_03524 8.1e-246 moeA 2.10.1.1 H molybdopterin
MDGJMAFB_03525 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MDGJMAFB_03526 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MDGJMAFB_03527 1e-144 yknT
MDGJMAFB_03528 1.5e-93 rok K Repressor of ComK
MDGJMAFB_03529 6.3e-81 ykuV CO thiol-disulfide
MDGJMAFB_03530 2.5e-100 ykuU O Alkyl hydroperoxide reductase
MDGJMAFB_03531 2.6e-141 ykuT M Mechanosensitive ion channel
MDGJMAFB_03532 9e-37 ykuS S Belongs to the UPF0180 family
MDGJMAFB_03533 2.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MDGJMAFB_03534 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MDGJMAFB_03535 3.2e-80 fld C Flavodoxin
MDGJMAFB_03536 4.7e-176 ykuO
MDGJMAFB_03537 6.5e-84 fld C Flavodoxin domain
MDGJMAFB_03538 3.5e-168 ccpC K Transcriptional regulator
MDGJMAFB_03539 1.6e-76 ykuL S CBS domain
MDGJMAFB_03540 3.9e-27 ykzF S Antirepressor AbbA
MDGJMAFB_03541 4.4e-94 ykuK S Ribonuclease H-like
MDGJMAFB_03542 3.9e-37 ykuJ S protein conserved in bacteria
MDGJMAFB_03543 5.2e-234 ykuI T Diguanylate phosphodiesterase
MDGJMAFB_03545 0.0 3.2.1.132 M Putative peptidoglycan binding domain
MDGJMAFB_03546 1.4e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDGJMAFB_03547 4.7e-165 ykuE S Metallophosphoesterase
MDGJMAFB_03548 1.7e-84 ykuD S protein conserved in bacteria
MDGJMAFB_03549 9.9e-236 ykuC EGP Major facilitator Superfamily
MDGJMAFB_03550 1.7e-84 ykyB S YkyB-like protein
MDGJMAFB_03551 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
MDGJMAFB_03552 2.2e-15
MDGJMAFB_03553 6.3e-221 patA 2.6.1.1 E Aminotransferase
MDGJMAFB_03554 0.0 pilS 2.7.13.3 T Histidine kinase
MDGJMAFB_03555 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
MDGJMAFB_03556 8e-124 ykwD J protein with SCP PR1 domains
MDGJMAFB_03557 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
MDGJMAFB_03558 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MDGJMAFB_03559 2.5e-262 mcpC NT chemotaxis protein
MDGJMAFB_03560 1.8e-127 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDGJMAFB_03561 3.7e-201 splB 4.1.99.14 L Spore photoproduct lyase
MDGJMAFB_03562 7.2e-39 splA S Transcriptional regulator
MDGJMAFB_03563 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDGJMAFB_03564 2.1e-39 ptsH G phosphocarrier protein HPr
MDGJMAFB_03565 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDGJMAFB_03566 7.6e-128 glcT K antiterminator
MDGJMAFB_03567 5.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
MDGJMAFB_03568 4.3e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MDGJMAFB_03569 1e-09
MDGJMAFB_03570 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MDGJMAFB_03571 9.2e-89 stoA CO thiol-disulfide
MDGJMAFB_03572 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDGJMAFB_03573 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
MDGJMAFB_03574 2.8e-28
MDGJMAFB_03575 6e-25 ykvS S protein conserved in bacteria
MDGJMAFB_03576 5.6e-46 ykvR S Protein of unknown function (DUF3219)
MDGJMAFB_03577 3.4e-161 G Glycosyl hydrolases family 18
MDGJMAFB_03578 1.2e-35 3.5.1.104 M LysM domain
MDGJMAFB_03579 2.6e-216 ykvP 3.5.1.28 M Glycosyl transferases group 1
MDGJMAFB_03580 1.8e-133 IQ Enoyl-(Acyl carrier protein) reductase
MDGJMAFB_03581 3.4e-61 ykvN K Transcriptional regulator
MDGJMAFB_03582 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MDGJMAFB_03583 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MDGJMAFB_03584 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MDGJMAFB_03585 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MDGJMAFB_03586 7.6e-178 ykvI S membrane
MDGJMAFB_03587 0.0 clpE O Belongs to the ClpA ClpB family
MDGJMAFB_03588 1e-137 motA N flagellar motor
MDGJMAFB_03589 2.5e-125 motB N Flagellar motor protein
MDGJMAFB_03590 1.3e-75 ykvE K transcriptional
MDGJMAFB_03591 5.3e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
MDGJMAFB_03592 1.8e-64 eag
MDGJMAFB_03593 6.4e-09 S Spo0E like sporulation regulatory protein
MDGJMAFB_03594 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
MDGJMAFB_03595 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MDGJMAFB_03596 4.7e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MDGJMAFB_03597 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MDGJMAFB_03598 3.4e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MDGJMAFB_03599 1.4e-231 mtnE 2.6.1.83 E Aminotransferase
MDGJMAFB_03600 4.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MDGJMAFB_03601 2.4e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MDGJMAFB_03602 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MDGJMAFB_03604 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDGJMAFB_03605 0.0 kinE 2.7.13.3 T Histidine kinase
MDGJMAFB_03606 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MDGJMAFB_03607 2.2e-19 ykzE
MDGJMAFB_03608 1.2e-10 ydfR S Protein of unknown function (DUF421)
MDGJMAFB_03609 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
MDGJMAFB_03610 6.6e-154 htpX O Belongs to the peptidase M48B family
MDGJMAFB_03611 1.5e-124 ykrK S Domain of unknown function (DUF1836)
MDGJMAFB_03612 1.9e-26 sspD S small acid-soluble spore protein
MDGJMAFB_03613 1.7e-109 rsgI S Anti-sigma factor N-terminus
MDGJMAFB_03614 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDGJMAFB_03615 7.9e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MDGJMAFB_03616 6e-106 ykoX S membrane-associated protein
MDGJMAFB_03617 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
MDGJMAFB_03618 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MDGJMAFB_03619 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MDGJMAFB_03620 8.2e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MDGJMAFB_03621 0.0 ykoS
MDGJMAFB_03622 6e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
MDGJMAFB_03623 3.7e-99 ykoP G polysaccharide deacetylase
MDGJMAFB_03624 1.2e-216 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MDGJMAFB_03625 1.3e-81 mhqR K transcriptional
MDGJMAFB_03626 6.9e-26 ykoL
MDGJMAFB_03627 5.9e-18
MDGJMAFB_03628 1.4e-53 tnrA K transcriptional
MDGJMAFB_03629 2.2e-222 mgtE P Acts as a magnesium transporter
MDGJMAFB_03632 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
MDGJMAFB_03633 2.1e-112 ykoI S Peptidase propeptide and YPEB domain
MDGJMAFB_03634 8.3e-241 ykoH 2.7.13.3 T Histidine kinase
MDGJMAFB_03635 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDGJMAFB_03636 1.3e-108 ykoF S YKOF-related Family
MDGJMAFB_03637 1e-97 ykoE S ABC-type cobalt transport system, permease component
MDGJMAFB_03638 2.8e-304 P ABC transporter, ATP-binding protein
MDGJMAFB_03639 5.3e-136 ykoC P Cobalt transport protein
MDGJMAFB_03640 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDGJMAFB_03641 5.5e-175 isp O Belongs to the peptidase S8 family
MDGJMAFB_03642 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MDGJMAFB_03643 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
MDGJMAFB_03644 8.4e-72 ohrB O Organic hydroperoxide resistance protein
MDGJMAFB_03645 1.7e-73 ohrR K COG1846 Transcriptional regulators
MDGJMAFB_03646 1.3e-70 ohrA O Organic hydroperoxide resistance protein
MDGJMAFB_03647 9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MDGJMAFB_03648 1.5e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDGJMAFB_03649 1.1e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MDGJMAFB_03650 7e-50 ykkD P Multidrug resistance protein
MDGJMAFB_03651 1.3e-54 ykkC P Multidrug resistance protein
MDGJMAFB_03652 5.1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MDGJMAFB_03653 6.7e-98 ykkA S Protein of unknown function (DUF664)
MDGJMAFB_03654 2.7e-129 ykjA S Protein of unknown function (DUF421)
MDGJMAFB_03655 7.2e-09
MDGJMAFB_03656 6.6e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MDGJMAFB_03657 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MDGJMAFB_03658 2e-160 ykgA E Amidinotransferase
MDGJMAFB_03659 9e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
MDGJMAFB_03660 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
MDGJMAFB_03661 2.2e-165 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MDGJMAFB_03662 8.3e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MDGJMAFB_03663 7.6e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MDGJMAFB_03664 0.0 dppE E ABC transporter substrate-binding protein
MDGJMAFB_03665 6.6e-187 dppD P Belongs to the ABC transporter superfamily
MDGJMAFB_03666 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDGJMAFB_03667 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDGJMAFB_03668 3.3e-152 dppA E D-aminopeptidase
MDGJMAFB_03669 5.3e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
MDGJMAFB_03670 3.4e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDGJMAFB_03672 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MDGJMAFB_03673 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MDGJMAFB_03674 6.7e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MDGJMAFB_03675 2.3e-240 steT E amino acid
MDGJMAFB_03676 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
MDGJMAFB_03677 7.6e-175 pit P phosphate transporter
MDGJMAFB_03678 5.2e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MDGJMAFB_03679 6.7e-23 spoIISB S Stage II sporulation protein SB
MDGJMAFB_03681 1e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MDGJMAFB_03682 9.3e-40 xhlB S SPP1 phage holin
MDGJMAFB_03683 2.8e-39 xhlA S Haemolysin XhlA
MDGJMAFB_03684 1.2e-154 xepA
MDGJMAFB_03685 1.4e-22 xkdX
MDGJMAFB_03686 2.6e-55 xkdW S XkdW protein
MDGJMAFB_03687 5e-261
MDGJMAFB_03688 6.7e-41
MDGJMAFB_03689 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MDGJMAFB_03690 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MDGJMAFB_03691 2.4e-69 xkdS S Protein of unknown function (DUF2634)
MDGJMAFB_03692 6.1e-39 xkdR S Protein of unknown function (DUF2577)
MDGJMAFB_03693 2e-180 yqbQ 3.2.1.96 G NLP P60 protein
MDGJMAFB_03694 4.1e-121 xkdP S Lysin motif
MDGJMAFB_03695 0.0 xkdO L Transglycosylase SLT domain
MDGJMAFB_03696 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
MDGJMAFB_03697 1e-75 xkdM S Phage tail tube protein
MDGJMAFB_03698 2.5e-256 xkdK S Phage tail sheath C-terminal domain
MDGJMAFB_03699 9.3e-77 xkdJ
MDGJMAFB_03700 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
MDGJMAFB_03701 8.7e-65 yqbH S Domain of unknown function (DUF3599)
MDGJMAFB_03702 7.9e-64 yqbG S Protein of unknown function (DUF3199)
MDGJMAFB_03703 1.3e-168 xkdG S Phage capsid family
MDGJMAFB_03704 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MDGJMAFB_03705 4.6e-285 yqbA S portal protein
MDGJMAFB_03706 1.4e-253 xtmB S phage terminase, large subunit
MDGJMAFB_03707 4.1e-139 xtmA L phage terminase small subunit
MDGJMAFB_03708 1.6e-83 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MDGJMAFB_03709 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
MDGJMAFB_03712 4.1e-118 xkdC L Bacterial dnaA protein
MDGJMAFB_03713 1e-156 xkdB K sequence-specific DNA binding
MDGJMAFB_03715 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
MDGJMAFB_03716 2.3e-110 xkdA E IrrE N-terminal-like domain
MDGJMAFB_03717 2.8e-159 ydbD P Catalase
MDGJMAFB_03718 2.1e-111 yjqB S Pfam:DUF867
MDGJMAFB_03719 6.1e-61 yjqA S Bacterial PH domain
MDGJMAFB_03720 6.1e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
MDGJMAFB_03721 6.3e-41 S YCII-related domain
MDGJMAFB_03723 1e-212 S response regulator aspartate phosphatase
MDGJMAFB_03724 3.3e-244 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
MDGJMAFB_03725 2.3e-78 yjoA S DinB family
MDGJMAFB_03726 2.8e-129 MA20_18170 S membrane transporter protein
MDGJMAFB_03727 8.7e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MDGJMAFB_03728 4.7e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MDGJMAFB_03729 5.2e-184 exuR K transcriptional
MDGJMAFB_03730 1.6e-225 exuT G Sugar (and other) transporter
MDGJMAFB_03731 9.8e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MDGJMAFB_03732 2.9e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MDGJMAFB_03733 2.4e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
MDGJMAFB_03734 7.1e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MDGJMAFB_03735 3.7e-249 yjmB G symporter YjmB
MDGJMAFB_03736 2.7e-279 uxaC 5.3.1.12 G glucuronate isomerase
MDGJMAFB_03737 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
MDGJMAFB_03738 7.1e-66 yjlC S Protein of unknown function (DUF1641)
MDGJMAFB_03739 3.4e-91 yjlB S Cupin domain
MDGJMAFB_03740 1.9e-175 yjlA EG Putative multidrug resistance efflux transporter
MDGJMAFB_03741 3.4e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
MDGJMAFB_03742 5.6e-122 ybbM S transport system, permease component
MDGJMAFB_03743 3.6e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MDGJMAFB_03744 8.2e-30
MDGJMAFB_03745 2.9e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MDGJMAFB_03746 8.3e-221 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
MDGJMAFB_03748 2.2e-116 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
MDGJMAFB_03749 8.7e-07 S Domain of unknown function (DUF4352)
MDGJMAFB_03750 1.6e-94 yjgD S Protein of unknown function (DUF1641)
MDGJMAFB_03751 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MDGJMAFB_03752 7.6e-103 yjgB S Domain of unknown function (DUF4309)
MDGJMAFB_03753 4.6e-45 T PhoQ Sensor
MDGJMAFB_03754 7.8e-163 yjfC O Predicted Zn-dependent protease (DUF2268)
MDGJMAFB_03755 2.3e-20 yjfB S Putative motility protein
MDGJMAFB_03756 3e-81 S Protein of unknown function (DUF2690)
MDGJMAFB_03757 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
MDGJMAFB_03759 7.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MDGJMAFB_03760 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
MDGJMAFB_03761 4.2e-29 S Domain of unknown function (DUF4177)
MDGJMAFB_03762 6.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDGJMAFB_03764 1e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
MDGJMAFB_03765 4.1e-50 yjdF S Protein of unknown function (DUF2992)
MDGJMAFB_03766 1.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MDGJMAFB_03767 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
MDGJMAFB_03768 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
MDGJMAFB_03770 2e-140 IQ Enoyl-(Acyl carrier protein) reductase
MDGJMAFB_03771 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
MDGJMAFB_03772 4.2e-92 yqaS L DNA packaging
MDGJMAFB_03773 4.1e-49 S YjcQ protein
MDGJMAFB_03774 2.1e-72 yjcP
MDGJMAFB_03775 3.6e-79 L Transposase
MDGJMAFB_03778 2.6e-44 yjcN
MDGJMAFB_03779 4.6e-190 S Putative amidase domain
MDGJMAFB_03783 1.5e-209 yjcL S Protein of unknown function (DUF819)
MDGJMAFB_03784 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
MDGJMAFB_03785 8.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MDGJMAFB_03786 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MDGJMAFB_03787 1e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
MDGJMAFB_03788 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MDGJMAFB_03789 1.3e-70 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDGJMAFB_03790 1.7e-38
MDGJMAFB_03791 0.0 yjcD 3.6.4.12 L DNA helicase
MDGJMAFB_03792 2.9e-38 spoVIF S Stage VI sporulation protein F
MDGJMAFB_03795 4.3e-56 yjcA S Protein of unknown function (DUF1360)
MDGJMAFB_03796 3.2e-49 cotV S Spore Coat Protein X and V domain
MDGJMAFB_03797 7.4e-23 cotW
MDGJMAFB_03798 1.2e-67 cotX S Spore Coat Protein X and V domain
MDGJMAFB_03799 7.6e-96 cotY S Spore coat protein Z
MDGJMAFB_03800 4.4e-82 cotZ S Spore coat protein
MDGJMAFB_03801 5.9e-54 yjbX S Spore coat protein
MDGJMAFB_03802 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MDGJMAFB_03803 6.9e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MDGJMAFB_03804 6.7e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MDGJMAFB_03805 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MDGJMAFB_03806 6.7e-30 thiS H thiamine diphosphate biosynthetic process
MDGJMAFB_03807 2.3e-217 thiO 1.4.3.19 E Glycine oxidase
MDGJMAFB_03808 1.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
MDGJMAFB_03809 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MDGJMAFB_03810 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MDGJMAFB_03811 1.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MDGJMAFB_03812 4e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDGJMAFB_03813 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDGJMAFB_03814 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
MDGJMAFB_03815 9.3e-62 yjbL S Belongs to the UPF0738 family
MDGJMAFB_03816 1e-99 yjbK S protein conserved in bacteria
MDGJMAFB_03817 2.3e-96 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MDGJMAFB_03818 3.7e-72 yjbI S Bacterial-like globin
MDGJMAFB_03819 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MDGJMAFB_03821 1.8e-20
MDGJMAFB_03822 0.0 pepF E oligoendopeptidase F
MDGJMAFB_03823 8.4e-125 yjbF S Competence protein
MDGJMAFB_03824 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MDGJMAFB_03825 6e-112 yjbE P Integral membrane protein TerC family
MDGJMAFB_03826 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDGJMAFB_03827 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDGJMAFB_03828 2.8e-205 yjbB EGP Major Facilitator Superfamily
MDGJMAFB_03829 5.5e-172 oppF E Belongs to the ABC transporter superfamily
MDGJMAFB_03830 6.8e-198 oppD P Belongs to the ABC transporter superfamily
MDGJMAFB_03831 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDGJMAFB_03832 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDGJMAFB_03833 0.0 oppA E ABC transporter substrate-binding protein
MDGJMAFB_03834 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MDGJMAFB_03835 5.5e-146 yjbA S Belongs to the UPF0736 family
MDGJMAFB_03836 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDGJMAFB_03837 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDGJMAFB_03838 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
MDGJMAFB_03839 2.7e-185 appF E Belongs to the ABC transporter superfamily
MDGJMAFB_03840 1.8e-184 appD P Belongs to the ABC transporter superfamily
MDGJMAFB_03841 7.3e-149 yjaZ O Zn-dependent protease
MDGJMAFB_03842 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MDGJMAFB_03843 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MDGJMAFB_03844 2.7e-22 yjzB
MDGJMAFB_03845 7.3e-26 comZ S ComZ
MDGJMAFB_03846 2.5e-183 med S Transcriptional activator protein med
MDGJMAFB_03847 1.2e-100 yjaV
MDGJMAFB_03848 6.8e-141 yjaU I carboxylic ester hydrolase activity
MDGJMAFB_03849 2.3e-16 yjzD S Protein of unknown function (DUF2929)
MDGJMAFB_03850 9.5e-28 yjzC S YjzC-like protein
MDGJMAFB_03851 1.2e-174 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MDGJMAFB_03852 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MDGJMAFB_03853 3.7e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MDGJMAFB_03854 1.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MDGJMAFB_03855 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MDGJMAFB_03856 7.7e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MDGJMAFB_03857 2.3e-198 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MDGJMAFB_03858 1.7e-88 norB G Major Facilitator Superfamily
MDGJMAFB_03859 3.2e-267 yitY C D-arabinono-1,4-lactone oxidase
MDGJMAFB_03860 1.5e-22 pilT S Proteolipid membrane potential modulator
MDGJMAFB_03861 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
MDGJMAFB_03862 1.9e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MDGJMAFB_03863 4.6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MDGJMAFB_03865 1.2e-17 S Protein of unknown function (DUF3813)
MDGJMAFB_03866 5e-73 ipi S Intracellular proteinase inhibitor
MDGJMAFB_03867 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MDGJMAFB_03868 9.3e-158 yitS S protein conserved in bacteria
MDGJMAFB_03869 9.9e-310 nprB 3.4.24.28 E Peptidase M4
MDGJMAFB_03870 1.4e-44 yitR S Domain of unknown function (DUF3784)
MDGJMAFB_03871 6.6e-94
MDGJMAFB_03872 1.5e-58 K Transcriptional regulator PadR-like family
MDGJMAFB_03873 2.9e-96 S Sporulation delaying protein SdpA
MDGJMAFB_03874 2.8e-171
MDGJMAFB_03875 8.5e-94
MDGJMAFB_03876 6.9e-161 cvfB S protein conserved in bacteria
MDGJMAFB_03877 5.6e-54 yajQ S Belongs to the UPF0234 family
MDGJMAFB_03878 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MDGJMAFB_03879 1.2e-71 yjcF S Acetyltransferase (GNAT) domain
MDGJMAFB_03880 2.1e-13 yitH K Acetyltransferase (GNAT) domain
MDGJMAFB_03881 2.3e-116 yitH K Acetyltransferase (GNAT) domain
MDGJMAFB_03882 1.5e-228 yitG EGP Major facilitator Superfamily
MDGJMAFB_03883 1.1e-219 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MDGJMAFB_03884 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDGJMAFB_03885 7.1e-141 yitD 4.4.1.19 S synthase
MDGJMAFB_03886 6.7e-122 comB 3.1.3.71 H Belongs to the ComB family
MDGJMAFB_03887 2.1e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MDGJMAFB_03888 2.7e-232 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MDGJMAFB_03889 1.4e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MDGJMAFB_03890 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MDGJMAFB_03891 2e-35 mcbG S Pentapeptide repeats (9 copies)
MDGJMAFB_03892 2.4e-275 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDGJMAFB_03893 2.7e-106 argO S Lysine exporter protein LysE YggA
MDGJMAFB_03894 7e-92 yisT S DinB family
MDGJMAFB_03895 8.8e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
MDGJMAFB_03896 6.9e-184 purR K helix_turn _helix lactose operon repressor
MDGJMAFB_03897 1.2e-160 yisR K Transcriptional regulator
MDGJMAFB_03898 8.9e-243 yisQ V Mate efflux family protein
MDGJMAFB_03899 2.6e-149 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
MDGJMAFB_03900 5.7e-86 yizA S Damage-inducible protein DinB
MDGJMAFB_03901 0.0 asnO 6.3.5.4 E Asparagine synthase
MDGJMAFB_03902 3.1e-101 yisN S Protein of unknown function (DUF2777)
MDGJMAFB_03903 0.0 wprA O Belongs to the peptidase S8 family
MDGJMAFB_03904 3e-57 yisL S UPF0344 protein
MDGJMAFB_03905 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MDGJMAFB_03906 1.5e-172 cotH M Spore Coat
MDGJMAFB_03907 1.5e-22 yisI S Spo0E like sporulation regulatory protein
MDGJMAFB_03908 1.9e-33 gerPA S Spore germination protein
MDGJMAFB_03909 4e-34 gerPB S cell differentiation
MDGJMAFB_03910 1.8e-54 gerPC S Spore germination protein
MDGJMAFB_03911 6.3e-24 gerPD S Spore germination protein
MDGJMAFB_03912 3e-66 gerPE S Spore germination protein GerPE
MDGJMAFB_03913 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
MDGJMAFB_03914 3e-50 yisB V COG1403 Restriction endonuclease
MDGJMAFB_03915 0.0 sbcC L COG0419 ATPase involved in DNA repair
MDGJMAFB_03916 3.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MDGJMAFB_03917 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MDGJMAFB_03918 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MDGJMAFB_03919 2.2e-78 yhjR S Rubrerythrin
MDGJMAFB_03920 0.0 S Sugar transport-related sRNA regulator N-term
MDGJMAFB_03921 1.2e-214 EGP Transmembrane secretion effector
MDGJMAFB_03922 1.9e-201 abrB S membrane
MDGJMAFB_03923 1.7e-187 yhjM 5.1.1.1 K Transcriptional regulator
MDGJMAFB_03924 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MDGJMAFB_03925 5.8e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
MDGJMAFB_03926 1.3e-198 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
MDGJMAFB_03927 5.8e-214 glcP G Major Facilitator Superfamily
MDGJMAFB_03928 5.9e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
MDGJMAFB_03929 1.8e-281 yhjG CH FAD binding domain
MDGJMAFB_03930 1.3e-90 sipV 3.4.21.89 U Belongs to the peptidase S26 family
MDGJMAFB_03931 9.1e-110 yhjE S SNARE associated Golgi protein
MDGJMAFB_03932 3.3e-59 yhjD
MDGJMAFB_03933 6.9e-27 yhjC S Protein of unknown function (DUF3311)
MDGJMAFB_03934 2.6e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDGJMAFB_03935 3.3e-40 yhjA S Excalibur calcium-binding domain
MDGJMAFB_03936 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
MDGJMAFB_03937 4.2e-109 comK K Competence transcription factor
MDGJMAFB_03938 1.3e-32 yhzC S IDEAL
MDGJMAFB_03939 3.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDGJMAFB_03940 6.1e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MDGJMAFB_03941 1.7e-182 hemAT NT chemotaxis protein
MDGJMAFB_03942 5e-91 bioY S BioY family
MDGJMAFB_03943 7.8e-274 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MDGJMAFB_03944 4.2e-195 vraB 2.3.1.9 I Belongs to the thiolase family
MDGJMAFB_03945 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MDGJMAFB_03946 4.3e-159 yfmC M Periplasmic binding protein
MDGJMAFB_03947 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
MDGJMAFB_03948 7.3e-77 VY92_01935 K acetyltransferase
MDGJMAFB_03949 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
MDGJMAFB_03950 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
MDGJMAFB_03951 1.9e-65 yhfM
MDGJMAFB_03952 2e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MDGJMAFB_03953 5.5e-110 yhfK GM NmrA-like family
MDGJMAFB_03954 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
MDGJMAFB_03955 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MDGJMAFB_03956 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDGJMAFB_03957 3.7e-72 3.4.13.21 S ASCH
MDGJMAFB_03958 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
MDGJMAFB_03959 4.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
MDGJMAFB_03960 1.5e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MDGJMAFB_03961 9.2e-232 yhgE S YhgE Pip N-terminal domain protein
MDGJMAFB_03962 5.4e-101 yhgD K Transcriptional regulator
MDGJMAFB_03963 1.9e-264 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MDGJMAFB_03964 3.1e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MDGJMAFB_03965 1.5e-200 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MDGJMAFB_03966 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MDGJMAFB_03967 3.7e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MDGJMAFB_03968 1.6e-33 1.15.1.2 C Rubrerythrin
MDGJMAFB_03969 1.6e-244 yhfA C membrane
MDGJMAFB_03970 1.4e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MDGJMAFB_03971 3.1e-114 ecsC S EcsC protein family
MDGJMAFB_03972 7e-215 ecsB U ABC transporter
MDGJMAFB_03973 4.6e-137 ecsA V transporter (ATP-binding protein)
MDGJMAFB_03974 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MDGJMAFB_03975 2.9e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MDGJMAFB_03976 2.4e-79 trpP S Tryptophan transporter TrpP
MDGJMAFB_03977 7e-39 yhaH S YtxH-like protein
MDGJMAFB_03978 1e-113 hpr K Negative regulator of protease production and sporulation
MDGJMAFB_03979 1.1e-53 yhaI S Protein of unknown function (DUF1878)
MDGJMAFB_03980 8.7e-90 yhaK S Putative zincin peptidase
MDGJMAFB_03981 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDGJMAFB_03982 1.6e-21 yhaL S Sporulation protein YhaL
MDGJMAFB_03983 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
MDGJMAFB_03984 0.0 yhaN L AAA domain
MDGJMAFB_03985 1.2e-222 yhaO L DNA repair exonuclease
MDGJMAFB_03986 6.1e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MDGJMAFB_03987 5.7e-166 yhaQ S ABC transporter, ATP-binding protein
MDGJMAFB_03988 1.1e-26 S YhzD-like protein
MDGJMAFB_03989 4.9e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
MDGJMAFB_03991 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
MDGJMAFB_03992 2.8e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
MDGJMAFB_03993 1.8e-292 hemZ H coproporphyrinogen III oxidase
MDGJMAFB_03994 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
MDGJMAFB_03995 1.4e-181 yhaZ L DNA alkylation repair enzyme
MDGJMAFB_03996 9.5e-48 yheA S Belongs to the UPF0342 family
MDGJMAFB_03997 2.6e-200 yheB S Belongs to the UPF0754 family
MDGJMAFB_03998 4.3e-216 yheC HJ YheC/D like ATP-grasp
MDGJMAFB_03999 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MDGJMAFB_04000 1.3e-36 yheE S Family of unknown function (DUF5342)
MDGJMAFB_04001 6.3e-28 sspB S spore protein
MDGJMAFB_04002 6.5e-108 yheG GM NAD(P)H-binding
MDGJMAFB_04003 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MDGJMAFB_04004 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MDGJMAFB_04005 3.4e-84 nhaX T Belongs to the universal stress protein A family
MDGJMAFB_04006 1e-230 nhaC C Na H antiporter
MDGJMAFB_04007 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MDGJMAFB_04008 3e-148 yheN G deacetylase
MDGJMAFB_04009 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MDGJMAFB_04010 9.6e-203 yhdY M Mechanosensitive ion channel
MDGJMAFB_04012 1.8e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MDGJMAFB_04013 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDGJMAFB_04014 1.3e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDGJMAFB_04015 2.5e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
MDGJMAFB_04016 2e-222 yhdR 2.6.1.1 E Aminotransferase
MDGJMAFB_04017 4.1e-74 cueR K transcriptional
MDGJMAFB_04018 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MDGJMAFB_04019 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MDGJMAFB_04020 1.5e-191 yhdN C Aldo keto reductase
MDGJMAFB_04021 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
MDGJMAFB_04022 6.6e-201 yhdL S Sigma factor regulator N-terminal
MDGJMAFB_04023 8.1e-45 yhdK S Sigma-M inhibitor protein
MDGJMAFB_04024 1.7e-75 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDGJMAFB_04025 2e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDGJMAFB_04026 8.2e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MDGJMAFB_04027 3.4e-250 yhdG E amino acid
MDGJMAFB_04028 2.7e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDGJMAFB_04029 2.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
MDGJMAFB_04030 3.8e-162 citR K Transcriptional regulator
MDGJMAFB_04031 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MDGJMAFB_04032 1.9e-253 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MDGJMAFB_04033 6.3e-276 ycgB S Stage V sporulation protein R
MDGJMAFB_04034 1.5e-238 ygxB M Conserved TM helix
MDGJMAFB_04035 1e-75 nsrR K Transcriptional regulator
MDGJMAFB_04036 8.7e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MDGJMAFB_04037 4.8e-54 yhdC S Protein of unknown function (DUF3889)
MDGJMAFB_04038 1.2e-38 yhdB S YhdB-like protein
MDGJMAFB_04039 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
MDGJMAFB_04040 1.7e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDGJMAFB_04041 3e-212 yhcY 2.7.13.3 T Histidine kinase
MDGJMAFB_04042 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MDGJMAFB_04043 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MDGJMAFB_04044 3.9e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MDGJMAFB_04045 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MDGJMAFB_04046 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MDGJMAFB_04047 1.1e-258 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDGJMAFB_04048 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MDGJMAFB_04049 3.9e-119 yhcW 5.4.2.6 S hydrolase
MDGJMAFB_04050 9.9e-68 yhcV S COG0517 FOG CBS domain
MDGJMAFB_04051 1e-66 yhcU S Family of unknown function (DUF5365)
MDGJMAFB_04052 9.6e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDGJMAFB_04053 1.7e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MDGJMAFB_04054 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
MDGJMAFB_04055 5.2e-100 yhcQ M Spore coat protein
MDGJMAFB_04056 2.5e-167 yhcP
MDGJMAFB_04057 3.5e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDGJMAFB_04058 3e-40 yhcM
MDGJMAFB_04059 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDGJMAFB_04060 3.4e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
MDGJMAFB_04061 2.2e-151 metQ M Belongs to the nlpA lipoprotein family
MDGJMAFB_04062 1e-30 cspB K Cold-shock protein
MDGJMAFB_04063 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MDGJMAFB_04064 5e-165 yhcH V ABC transporter, ATP-binding protein
MDGJMAFB_04065 4e-122 yhcG V ABC transporter, ATP-binding protein
MDGJMAFB_04066 5.6e-59 yhcF K Transcriptional regulator

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)