ORF_ID e_value Gene_name EC_number CAZy COGs Description
HKMNKKGD_00001 4.8e-47 mraZ K Belongs to the MraZ family
HKMNKKGD_00002 1.9e-62 S Protein of unknown function (DUF3397)
HKMNKKGD_00003 4.2e-175 corA P CorA-like Mg2+ transporter protein
HKMNKKGD_00004 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HKMNKKGD_00005 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKMNKKGD_00006 6.3e-114 ywnB S NAD(P)H-binding
HKMNKKGD_00007 8.3e-209 brnQ U Component of the transport system for branched-chain amino acids
HKMNKKGD_00008 1.4e-30 3.4.13.21, 3.4.15.6 E Belongs to the peptidase S51 family
HKMNKKGD_00009 1.1e-161 rrmA 2.1.1.187 H Methyltransferase
HKMNKKGD_00010 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKMNKKGD_00011 4.3e-206 XK27_05220 S AI-2E family transporter
HKMNKKGD_00012 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HKMNKKGD_00013 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HKMNKKGD_00014 1.1e-115 cutC P Participates in the control of copper homeostasis
HKMNKKGD_00015 8.9e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HKMNKKGD_00016 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKMNKKGD_00017 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
HKMNKKGD_00018 3.6e-114 yjbH Q Thioredoxin
HKMNKKGD_00019 0.0 pepF E oligoendopeptidase F
HKMNKKGD_00020 7.6e-205 coiA 3.6.4.12 S Competence protein
HKMNKKGD_00021 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKMNKKGD_00022 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKMNKKGD_00023 3.8e-139 yhfI S Metallo-beta-lactamase superfamily
HKMNKKGD_00024 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HKMNKKGD_00034 5.5e-08
HKMNKKGD_00049 5.5e-08
HKMNKKGD_00061 1.5e-42 S COG NOG38524 non supervised orthologous group
HKMNKKGD_00062 3.5e-64
HKMNKKGD_00063 1.6e-75 yugI 5.3.1.9 J general stress protein
HKMNKKGD_00064 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKMNKKGD_00065 3e-119 dedA S SNARE-like domain protein
HKMNKKGD_00066 2.1e-117 S Protein of unknown function (DUF1461)
HKMNKKGD_00067 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKMNKKGD_00068 1.5e-80 yutD S Protein of unknown function (DUF1027)
HKMNKKGD_00069 1.5e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HKMNKKGD_00070 4.4e-117 S Calcineurin-like phosphoesterase
HKMNKKGD_00071 5.6e-253 cycA E Amino acid permease
HKMNKKGD_00072 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKMNKKGD_00073 1e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
HKMNKKGD_00075 1.7e-87 S Prokaryotic N-terminal methylation motif
HKMNKKGD_00076 8.6e-20
HKMNKKGD_00077 5.5e-83 gspG NU general secretion pathway protein
HKMNKKGD_00078 5.5e-43 comGC U competence protein ComGC
HKMNKKGD_00079 3.7e-188 comGB NU type II secretion system
HKMNKKGD_00080 5.6e-175 comGA NU Type II IV secretion system protein
HKMNKKGD_00081 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKMNKKGD_00082 8.3e-131 yebC K Transcriptional regulatory protein
HKMNKKGD_00083 3e-48 S DsrE/DsrF-like family
HKMNKKGD_00084 1.2e-163 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HKMNKKGD_00085 1.9e-181 ccpA K catabolite control protein A
HKMNKKGD_00086 2.4e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HKMNKKGD_00087 1.5e-80 K helix_turn_helix, mercury resistance
HKMNKKGD_00088 2.8e-56
HKMNKKGD_00089 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKMNKKGD_00090 2.6e-158 ykuT M mechanosensitive ion channel
HKMNKKGD_00091 1.1e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKMNKKGD_00092 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKMNKKGD_00093 6.5e-87 ykuL S (CBS) domain
HKMNKKGD_00094 9.5e-97 S Phosphoesterase
HKMNKKGD_00095 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKMNKKGD_00096 9e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HKMNKKGD_00097 7.6e-126 yslB S Protein of unknown function (DUF2507)
HKMNKKGD_00098 3.3e-52 trxA O Belongs to the thioredoxin family
HKMNKKGD_00099 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKMNKKGD_00100 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKMNKKGD_00101 1.6e-48 yrzB S Belongs to the UPF0473 family
HKMNKKGD_00102 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKMNKKGD_00103 2.4e-43 yrzL S Belongs to the UPF0297 family
HKMNKKGD_00104 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKMNKKGD_00105 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKMNKKGD_00106 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HKMNKKGD_00107 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKMNKKGD_00108 2.8e-29 yajC U Preprotein translocase
HKMNKKGD_00109 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKMNKKGD_00110 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKMNKKGD_00111 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKMNKKGD_00112 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKMNKKGD_00113 9.6e-89
HKMNKKGD_00114 0.0 S Bacterial membrane protein YfhO
HKMNKKGD_00115 1.3e-72
HKMNKKGD_00116 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKMNKKGD_00117 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKMNKKGD_00118 2.7e-154 ymdB S YmdB-like protein
HKMNKKGD_00119 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
HKMNKKGD_00120 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKMNKKGD_00121 1.9e-231 cinA 3.5.1.42 S Belongs to the CinA family
HKMNKKGD_00122 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKMNKKGD_00123 5.7e-110 ymfM S Helix-turn-helix domain
HKMNKKGD_00124 2.9e-251 ymfH S Peptidase M16
HKMNKKGD_00125 3.2e-231 ymfF S Peptidase M16 inactive domain protein
HKMNKKGD_00126 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
HKMNKKGD_00127 5.6e-155 aatB ET ABC transporter substrate-binding protein
HKMNKKGD_00128 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKMNKKGD_00129 4.6e-109 glnP P ABC transporter permease
HKMNKKGD_00130 1.2e-146 minD D Belongs to the ParA family
HKMNKKGD_00131 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKMNKKGD_00132 1.2e-88 mreD M rod shape-determining protein MreD
HKMNKKGD_00133 2.6e-144 mreC M Involved in formation and maintenance of cell shape
HKMNKKGD_00134 6.2e-161 mreB D cell shape determining protein MreB
HKMNKKGD_00135 1.3e-116 radC L DNA repair protein
HKMNKKGD_00136 4.7e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HKMNKKGD_00137 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKMNKKGD_00138 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKMNKKGD_00139 8e-235 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HKMNKKGD_00140 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKMNKKGD_00141 4.9e-218 iscS2 2.8.1.7 E Aminotransferase class V
HKMNKKGD_00143 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKMNKKGD_00144 1.1e-80 ytsP 1.8.4.14 T GAF domain-containing protein
HKMNKKGD_00145 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKMNKKGD_00146 5.2e-113 yktB S Belongs to the UPF0637 family
HKMNKKGD_00147 2.5e-80 yueI S Protein of unknown function (DUF1694)
HKMNKKGD_00148 7e-110 S Protein of unknown function (DUF1648)
HKMNKKGD_00149 8.6e-44 czrA K Helix-turn-helix domain
HKMNKKGD_00150 5.1e-232 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HKMNKKGD_00151 9.2e-42 2.7.1.191 G PTS system fructose IIA component
HKMNKKGD_00152 2.7e-104 G PTS system mannose fructose sorbose family IID component
HKMNKKGD_00153 3.6e-103 G PTS system sorbose-specific iic component
HKMNKKGD_00154 6e-66 2.7.1.191 G PTS system sorbose subfamily IIB component
HKMNKKGD_00155 5.9e-95 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HKMNKKGD_00156 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HKMNKKGD_00157 8e-238 rarA L recombination factor protein RarA
HKMNKKGD_00158 1.5e-38
HKMNKKGD_00159 6.2e-82 usp6 T universal stress protein
HKMNKKGD_00160 3.1e-201 bla2 3.5.2.6 V Beta-lactamase enzyme family
HKMNKKGD_00161 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HKMNKKGD_00162 5.6e-294 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HKMNKKGD_00163 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HKMNKKGD_00164 1.8e-187 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKMNKKGD_00165 1.6e-177 S Protein of unknown function (DUF2785)
HKMNKKGD_00166 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
HKMNKKGD_00167 2.2e-148 metQ M Belongs to the nlpA lipoprotein family
HKMNKKGD_00168 4.1e-111 metI U ABC transporter permease
HKMNKKGD_00169 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKMNKKGD_00170 3.6e-48 gcsH2 E glycine cleavage
HKMNKKGD_00171 9.3e-220 rodA D Belongs to the SEDS family
HKMNKKGD_00172 3.3e-33 S Protein of unknown function (DUF2969)
HKMNKKGD_00173 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HKMNKKGD_00174 2.7e-180 mbl D Cell shape determining protein MreB Mrl
HKMNKKGD_00175 2.1e-102 J Acetyltransferase (GNAT) domain
HKMNKKGD_00176 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKMNKKGD_00177 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HKMNKKGD_00178 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKMNKKGD_00179 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKMNKKGD_00180 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKMNKKGD_00181 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKMNKKGD_00182 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKMNKKGD_00183 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKMNKKGD_00184 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HKMNKKGD_00185 5e-232 pyrP F Permease
HKMNKKGD_00186 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKMNKKGD_00187 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKMNKKGD_00188 2e-191 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKMNKKGD_00189 1e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKMNKKGD_00190 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKMNKKGD_00191 1.2e-108 tdk 2.7.1.21 F thymidine kinase
HKMNKKGD_00192 1.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HKMNKKGD_00193 5.9e-137 cobQ S glutamine amidotransferase
HKMNKKGD_00194 9.8e-196 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKMNKKGD_00195 1.7e-190 ampC V Beta-lactamase
HKMNKKGD_00196 1.4e-29
HKMNKKGD_00197 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HKMNKKGD_00198 1.9e-58
HKMNKKGD_00199 5.3e-125
HKMNKKGD_00200 0.0 yfiC V ABC transporter
HKMNKKGD_00201 0.0 ycfI V ABC transporter, ATP-binding protein
HKMNKKGD_00202 3.3e-65 S Protein of unknown function (DUF1093)
HKMNKKGD_00203 3.8e-135 yxkH G Polysaccharide deacetylase
HKMNKKGD_00205 1.9e-65 K IrrE N-terminal-like domain
HKMNKKGD_00206 6.3e-16
HKMNKKGD_00207 5.4e-33 hol S Bacteriophage holin
HKMNKKGD_00208 1.2e-46
HKMNKKGD_00209 1.2e-179 M Glycosyl hydrolases family 25
HKMNKKGD_00211 5.1e-46 S Protein of unknown function (DUF1617)
HKMNKKGD_00212 0.0 sidC GT2,GT4 LM DNA recombination
HKMNKKGD_00213 5.9e-61
HKMNKKGD_00214 0.0 D NLP P60 protein
HKMNKKGD_00215 6.8e-22
HKMNKKGD_00216 2.8e-64
HKMNKKGD_00217 6.9e-78 S Phage tail tube protein, TTP
HKMNKKGD_00218 3.7e-55
HKMNKKGD_00219 2.7e-89
HKMNKKGD_00220 2.6e-50
HKMNKKGD_00221 1.2e-52
HKMNKKGD_00223 5.3e-176 S Phage major capsid protein E
HKMNKKGD_00224 2.9e-49
HKMNKKGD_00225 7.7e-14 S Domain of unknown function (DUF4355)
HKMNKKGD_00226 5.2e-162 S Phage Mu protein F like protein
HKMNKKGD_00227 3.8e-38 J Cysteine protease Prp
HKMNKKGD_00228 1.1e-267 S Phage portal protein, SPP1 Gp6-like
HKMNKKGD_00229 4.9e-240 ps334 S Terminase-like family
HKMNKKGD_00230 2.1e-79 L Terminase small subunit
HKMNKKGD_00231 4.1e-10 V HNH nucleases
HKMNKKGD_00233 2.5e-69 LO Belongs to the peptidase S16 family
HKMNKKGD_00235 1.9e-80 arpU S Phage transcriptional regulator, ArpU family
HKMNKKGD_00238 9.1e-65 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HKMNKKGD_00239 5e-34
HKMNKKGD_00240 4.9e-149 L DnaD domain protein
HKMNKKGD_00241 3.9e-76 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HKMNKKGD_00242 4.1e-78 recT L RecT family
HKMNKKGD_00243 1.4e-68
HKMNKKGD_00244 2.5e-14 S Domain of unknown function (DUF1508)
HKMNKKGD_00245 1.6e-75
HKMNKKGD_00246 2.9e-53
HKMNKKGD_00250 1.5e-17 K Cro/C1-type HTH DNA-binding domain
HKMNKKGD_00251 8.9e-07
HKMNKKGD_00255 7.5e-22 S protein disulfide oxidoreductase activity
HKMNKKGD_00256 6.1e-09 S Pfam:Peptidase_M78
HKMNKKGD_00257 8.5e-11 S DNA/RNA non-specific endonuclease
HKMNKKGD_00262 6.1e-13
HKMNKKGD_00263 3e-11 M LysM domain
HKMNKKGD_00267 1.4e-18 T Histidine kinase-like ATPases
HKMNKKGD_00268 4.6e-07 S STAS-like domain of unknown function (DUF4325)
HKMNKKGD_00269 1.4e-08 S PFAM PilT protein domain protein
HKMNKKGD_00270 1.8e-217 int L Belongs to the 'phage' integrase family
HKMNKKGD_00272 8.9e-30
HKMNKKGD_00274 2e-38
HKMNKKGD_00275 1.4e-43
HKMNKKGD_00276 0.0 L Transposase
HKMNKKGD_00277 7.3e-83 K MarR family
HKMNKKGD_00278 0.0 bztC D nuclear chromosome segregation
HKMNKKGD_00279 2.3e-246 M MucBP domain
HKMNKKGD_00280 2.7e-16
HKMNKKGD_00281 7.2e-17
HKMNKKGD_00282 5.2e-15
HKMNKKGD_00283 1.1e-18
HKMNKKGD_00284 1.6e-16
HKMNKKGD_00285 1.6e-16
HKMNKKGD_00286 1.6e-16
HKMNKKGD_00287 1.9e-18
HKMNKKGD_00288 1.6e-16
HKMNKKGD_00289 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
HKMNKKGD_00290 2.9e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HKMNKKGD_00291 0.0 macB3 V ABC transporter, ATP-binding protein
HKMNKKGD_00292 6.8e-24
HKMNKKGD_00293 3.9e-259 pgi 5.3.1.9 G Belongs to the GPI family
HKMNKKGD_00294 9.7e-155 glcU U sugar transport
HKMNKKGD_00295 9.4e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
HKMNKKGD_00296 2.9e-287 yclK 2.7.13.3 T Histidine kinase
HKMNKKGD_00297 1.6e-134 K response regulator
HKMNKKGD_00298 3e-243 XK27_08635 S UPF0210 protein
HKMNKKGD_00299 2.3e-38 gcvR T Belongs to the UPF0237 family
HKMNKKGD_00300 1.5e-169 EG EamA-like transporter family
HKMNKKGD_00302 7.7e-92 S ECF-type riboflavin transporter, S component
HKMNKKGD_00303 3.3e-47
HKMNKKGD_00304 3.7e-213 yceI EGP Major facilitator Superfamily
HKMNKKGD_00305 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
HKMNKKGD_00306 3.8e-23
HKMNKKGD_00308 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
HKMNKKGD_00309 2.8e-173 ykfC 3.4.14.13 M NlpC/P60 family
HKMNKKGD_00310 6.6e-81 K AsnC family
HKMNKKGD_00311 2e-35
HKMNKKGD_00312 5.1e-34
HKMNKKGD_00313 1.7e-218 2.7.7.65 T diguanylate cyclase
HKMNKKGD_00314 6.6e-295 S ABC transporter, ATP-binding protein
HKMNKKGD_00315 2e-106 3.2.2.20 K acetyltransferase
HKMNKKGD_00316 5.8e-82 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKMNKKGD_00317 2.7e-39
HKMNKKGD_00318 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HKMNKKGD_00319 1.4e-189 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKMNKKGD_00320 2.5e-161 degV S Uncharacterised protein, DegV family COG1307
HKMNKKGD_00321 7.3e-231 hom1 1.1.1.3 E Homoserine dehydrogenase
HKMNKKGD_00322 2.2e-243 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HKMNKKGD_00323 4.8e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HKMNKKGD_00324 1.4e-176 XK27_08835 S ABC transporter
HKMNKKGD_00325 3.3e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HKMNKKGD_00326 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
HKMNKKGD_00327 2.5e-258 npr 1.11.1.1 C NADH oxidase
HKMNKKGD_00328 1.5e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HKMNKKGD_00329 4.8e-137 terC P membrane
HKMNKKGD_00330 1.5e-84 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HKMNKKGD_00331 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKMNKKGD_00332 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HKMNKKGD_00333 2.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HKMNKKGD_00334 3.8e-134 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKMNKKGD_00335 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKMNKKGD_00336 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKMNKKGD_00337 2.3e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HKMNKKGD_00338 7.8e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKMNKKGD_00339 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKMNKKGD_00340 5.6e-214 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKMNKKGD_00341 6.5e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
HKMNKKGD_00342 1.8e-215 ysaA V RDD family
HKMNKKGD_00343 7.6e-166 corA P CorA-like Mg2+ transporter protein
HKMNKKGD_00344 3.4e-50 S Domain of unknown function (DU1801)
HKMNKKGD_00345 3.5e-13 rmeB K transcriptional regulator, MerR family
HKMNKKGD_00346 8e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKMNKKGD_00347 1.1e-186 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKMNKKGD_00348 3.7e-34
HKMNKKGD_00349 9.2e-112 S Protein of unknown function (DUF1211)
HKMNKKGD_00350 0.0 ydgH S MMPL family
HKMNKKGD_00351 3.3e-289 M domain protein
HKMNKKGD_00352 3.9e-75 yjcF S Acetyltransferase (GNAT) domain
HKMNKKGD_00353 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKMNKKGD_00354 0.0 glpQ 3.1.4.46 C phosphodiesterase
HKMNKKGD_00355 4e-197 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKMNKKGD_00356 2.3e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HKMNKKGD_00357 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
HKMNKKGD_00358 4.7e-180 3.6.4.13 S domain, Protein
HKMNKKGD_00359 3.6e-168 S Polyphosphate kinase 2 (PPK2)
HKMNKKGD_00360 2.5e-98 drgA C Nitroreductase family
HKMNKKGD_00361 3.1e-178 iunH2 3.2.2.1 F nucleoside hydrolase
HKMNKKGD_00362 3.4e-150 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKMNKKGD_00363 3.7e-154 glcU U sugar transport
HKMNKKGD_00364 2.1e-182 bglK_1 GK ROK family
HKMNKKGD_00365 3.7e-156 pflC 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKMNKKGD_00366 3.7e-134 yciT K DeoR C terminal sensor domain
HKMNKKGD_00367 0.0 ybiW 2.3.1.54 C Pyruvate formate lyase-like
HKMNKKGD_00368 9.1e-178 K sugar-binding domain protein
HKMNKKGD_00369 7.4e-124 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
HKMNKKGD_00370 4.2e-141 S Sucrose-6F-phosphate phosphohydrolase
HKMNKKGD_00371 6.4e-176 ccpB 5.1.1.1 K lacI family
HKMNKKGD_00372 3.6e-157 K Helix-turn-helix domain, rpiR family
HKMNKKGD_00373 7.9e-177 S Oxidoreductase family, NAD-binding Rossmann fold
HKMNKKGD_00374 5.9e-199 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
HKMNKKGD_00375 0.0 yjcE P Sodium proton antiporter
HKMNKKGD_00376 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKMNKKGD_00377 3.2e-106 pncA Q Isochorismatase family
HKMNKKGD_00378 1.4e-131
HKMNKKGD_00379 5.1e-125 skfE V ABC transporter
HKMNKKGD_00380 2.1e-64 yvoA_1 K Transcriptional regulator, GntR family
HKMNKKGD_00381 2.1e-45 S Enterocin A Immunity
HKMNKKGD_00382 7e-175 D Alpha beta
HKMNKKGD_00383 0.0 pepF2 E Oligopeptidase F
HKMNKKGD_00384 1.3e-72 K Transcriptional regulator
HKMNKKGD_00385 3e-164
HKMNKKGD_00387 0.0 L Transposase
HKMNKKGD_00388 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HKMNKKGD_00389 1.9e-68
HKMNKKGD_00390 1.9e-144 yjfP S Dienelactone hydrolase family
HKMNKKGD_00391 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
HKMNKKGD_00392 9.3e-206 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HKMNKKGD_00393 5.2e-47
HKMNKKGD_00394 6.3e-45
HKMNKKGD_00395 5e-82 yybC S Protein of unknown function (DUF2798)
HKMNKKGD_00396 1.7e-73
HKMNKKGD_00397 4e-60
HKMNKKGD_00398 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HKMNKKGD_00399 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
HKMNKKGD_00400 4.7e-79 uspA T universal stress protein
HKMNKKGD_00401 8.7e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKMNKKGD_00402 4.4e-20
HKMNKKGD_00403 4.2e-44 S zinc-ribbon domain
HKMNKKGD_00404 9.6e-70 S response to antibiotic
HKMNKKGD_00405 1.7e-48 K Cro/C1-type HTH DNA-binding domain
HKMNKKGD_00406 3.3e-21 S Protein of unknown function (DUF2929)
HKMNKKGD_00407 9.4e-225 lsgC M Glycosyl transferases group 1
HKMNKKGD_00408 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HKMNKKGD_00409 1.5e-163 S Putative esterase
HKMNKKGD_00410 2.4e-130 gntR2 K Transcriptional regulator
HKMNKKGD_00411 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKMNKKGD_00412 5.2e-139
HKMNKKGD_00413 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKMNKKGD_00414 5.5e-138 rrp8 K LytTr DNA-binding domain
HKMNKKGD_00415 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
HKMNKKGD_00416 7.7e-61
HKMNKKGD_00417 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
HKMNKKGD_00418 4.4e-58
HKMNKKGD_00419 1.8e-240 yhdP S Transporter associated domain
HKMNKKGD_00420 4.9e-87 nrdI F Belongs to the NrdI family
HKMNKKGD_00421 2.9e-269 yjcE P Sodium proton antiporter
HKMNKKGD_00422 1.1e-212 yttB EGP Major facilitator Superfamily
HKMNKKGD_00423 8.6e-63 K helix_turn_helix, mercury resistance
HKMNKKGD_00424 1.8e-173 C Zinc-binding dehydrogenase
HKMNKKGD_00425 8.5e-57 S SdpI/YhfL protein family
HKMNKKGD_00426 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKMNKKGD_00427 1.2e-260 gabR K Bacterial regulatory proteins, gntR family
HKMNKKGD_00428 5e-218 patA 2.6.1.1 E Aminotransferase
HKMNKKGD_00429 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKMNKKGD_00430 3e-18
HKMNKKGD_00431 1.7e-126 S membrane transporter protein
HKMNKKGD_00432 1.9e-161 mleR K LysR family
HKMNKKGD_00433 5.6e-115 ylbE GM NAD(P)H-binding
HKMNKKGD_00434 8.2e-96 wecD K Acetyltransferase (GNAT) family
HKMNKKGD_00435 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HKMNKKGD_00436 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKMNKKGD_00437 4.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
HKMNKKGD_00438 1.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKMNKKGD_00439 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKMNKKGD_00440 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKMNKKGD_00441 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HKMNKKGD_00442 1.2e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HKMNKKGD_00443 1.5e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKMNKKGD_00444 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HKMNKKGD_00445 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKMNKKGD_00446 1e-298 pucR QT Purine catabolism regulatory protein-like family
HKMNKKGD_00447 3.5e-236 pbuX F xanthine permease
HKMNKKGD_00448 2.4e-221 pbuG S Permease family
HKMNKKGD_00449 3.9e-162 GM NmrA-like family
HKMNKKGD_00450 6.5e-156 T EAL domain
HKMNKKGD_00451 2.6e-94
HKMNKKGD_00452 9.2e-253 pgaC GT2 M Glycosyl transferase
HKMNKKGD_00453 6.9e-124 2.1.1.14 E Methionine synthase
HKMNKKGD_00454 6.4e-216 purD 6.3.4.13 F Belongs to the GARS family
HKMNKKGD_00455 7.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HKMNKKGD_00456 2.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKMNKKGD_00457 9.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HKMNKKGD_00458 1.1e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKMNKKGD_00459 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKMNKKGD_00460 4.4e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKMNKKGD_00461 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKMNKKGD_00462 1.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HKMNKKGD_00463 7.4e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKMNKKGD_00464 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKMNKKGD_00465 7.5e-196 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKMNKKGD_00466 7.9e-225 XK27_09615 1.3.5.4 S reductase
HKMNKKGD_00467 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
HKMNKKGD_00468 8.4e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HKMNKKGD_00469 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HKMNKKGD_00470 9.2e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HKMNKKGD_00471 7.5e-149 S Alpha/beta hydrolase of unknown function (DUF915)
HKMNKKGD_00472 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
HKMNKKGD_00473 1.7e-139 cysA V ABC transporter, ATP-binding protein
HKMNKKGD_00474 0.0 V FtsX-like permease family
HKMNKKGD_00475 8e-42
HKMNKKGD_00476 7.9e-61 gntR1 K Transcriptional regulator, GntR family
HKMNKKGD_00477 6.9e-164 V ABC transporter, ATP-binding protein
HKMNKKGD_00478 2.9e-148
HKMNKKGD_00479 6.7e-81 uspA T universal stress protein
HKMNKKGD_00480 1.2e-35
HKMNKKGD_00481 4.2e-71 gtcA S Teichoic acid glycosylation protein
HKMNKKGD_00482 4.3e-88
HKMNKKGD_00483 2.7e-49
HKMNKKGD_00485 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
HKMNKKGD_00486 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
HKMNKKGD_00487 5.4e-118
HKMNKKGD_00488 1.5e-52
HKMNKKGD_00489 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HKMNKKGD_00490 1.4e-281 thrC 4.2.3.1 E Threonine synthase
HKMNKKGD_00491 4.5e-146 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HKMNKKGD_00492 1.5e-11 mcbG S Pentapeptide repeats (8 copies)
HKMNKKGD_00493 1.7e-111 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HKMNKKGD_00494 3.1e-101 3.6.1.13 L Belongs to the Nudix hydrolase family
HKMNKKGD_00495 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
HKMNKKGD_00496 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
HKMNKKGD_00497 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
HKMNKKGD_00498 8.4e-212 S Bacterial protein of unknown function (DUF871)
HKMNKKGD_00499 2.1e-232 S Sterol carrier protein domain
HKMNKKGD_00500 2.1e-225 EGP Major facilitator Superfamily
HKMNKKGD_00501 2.1e-88 niaR S 3H domain
HKMNKKGD_00502 2.3e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKMNKKGD_00503 1.3e-117 K Transcriptional regulator
HKMNKKGD_00504 3.2e-154 V ABC transporter
HKMNKKGD_00505 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
HKMNKKGD_00506 1.7e-246 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HKMNKKGD_00507 3.4e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKMNKKGD_00508 9.5e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKMNKKGD_00509 5.1e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HKMNKKGD_00510 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HKMNKKGD_00511 1.8e-130 gntR K UTRA
HKMNKKGD_00512 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
HKMNKKGD_00513 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HKMNKKGD_00514 1.8e-81
HKMNKKGD_00515 9.8e-152 S hydrolase
HKMNKKGD_00516 6.5e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKMNKKGD_00517 8.3e-152 EG EamA-like transporter family
HKMNKKGD_00518 1.3e-176 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HKMNKKGD_00519 1.2e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HKMNKKGD_00520 1.5e-233
HKMNKKGD_00521 4.2e-77 fld C Flavodoxin
HKMNKKGD_00522 0.0 M Bacterial Ig-like domain (group 3)
HKMNKKGD_00523 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HKMNKKGD_00524 2.7e-32
HKMNKKGD_00525 6.1e-129 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
HKMNKKGD_00526 2.2e-268 ycaM E amino acid
HKMNKKGD_00527 7.9e-79 K Winged helix DNA-binding domain
HKMNKKGD_00528 3.3e-166 S Oxidoreductase, aldo keto reductase family protein
HKMNKKGD_00529 5.7e-163 akr5f 1.1.1.346 S reductase
HKMNKKGD_00530 4.6e-163 K Transcriptional regulator
HKMNKKGD_00532 1.5e-42 S COG NOG38524 non supervised orthologous group
HKMNKKGD_00533 1.8e-84 hmpT S Pfam:DUF3816
HKMNKKGD_00534 1e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKMNKKGD_00535 3.9e-111
HKMNKKGD_00536 4.2e-149 M Glycosyl hydrolases family 25
HKMNKKGD_00537 5.9e-143 yvpB S Peptidase_C39 like family
HKMNKKGD_00538 1.1e-92 yueI S Protein of unknown function (DUF1694)
HKMNKKGD_00539 1.6e-115 S Protein of unknown function (DUF554)
HKMNKKGD_00540 2.6e-149 KT helix_turn_helix, mercury resistance
HKMNKKGD_00541 1.6e-123 L PFAM transposase IS116 IS110 IS902 family
HKMNKKGD_00542 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKMNKKGD_00543 6.6e-95 S Protein of unknown function (DUF1440)
HKMNKKGD_00544 5.2e-174 hrtB V ABC transporter permease
HKMNKKGD_00545 5.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HKMNKKGD_00546 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
HKMNKKGD_00547 1.4e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HKMNKKGD_00548 8.1e-99 1.5.1.3 H RibD C-terminal domain
HKMNKKGD_00549 4.1e-188 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKMNKKGD_00550 7.5e-110 S Membrane
HKMNKKGD_00551 1.2e-155 mleP3 S Membrane transport protein
HKMNKKGD_00552 3.4e-258 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HKMNKKGD_00553 7.6e-190 ynfM EGP Major facilitator Superfamily
HKMNKKGD_00554 2.8e-125 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HKMNKKGD_00555 1.1e-270 lmrB EGP Major facilitator Superfamily
HKMNKKGD_00556 2e-75 S Domain of unknown function (DUF4811)
HKMNKKGD_00557 1.8e-101 rimL J Acetyltransferase (GNAT) domain
HKMNKKGD_00558 1.2e-172 S Conserved hypothetical protein 698
HKMNKKGD_00559 3.7e-151 rlrG K Transcriptional regulator
HKMNKKGD_00560 1.2e-296 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HKMNKKGD_00561 6.9e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
HKMNKKGD_00562 1.6e-33 lytE M LysM domain protein
HKMNKKGD_00563 2.3e-52 lytE M LysM domain
HKMNKKGD_00564 1.7e-90 ogt 2.1.1.63 L Methyltransferase
HKMNKKGD_00565 3.6e-168 natA S ABC transporter, ATP-binding protein
HKMNKKGD_00566 4.7e-211 natB CP ABC-2 family transporter protein
HKMNKKGD_00567 1e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKMNKKGD_00568 2.5e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
HKMNKKGD_00569 3.2e-76 yphH S Cupin domain
HKMNKKGD_00570 1.9e-39 K transcriptional regulator, MerR family
HKMNKKGD_00571 2.3e-237 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HKMNKKGD_00572 0.0 ylbB V ABC transporter permease
HKMNKKGD_00573 7.5e-121 macB V ABC transporter, ATP-binding protein
HKMNKKGD_00575 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKMNKKGD_00576 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HKMNKKGD_00577 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HKMNKKGD_00578 2.4e-83
HKMNKKGD_00579 7.3e-86 yvbK 3.1.3.25 K GNAT family
HKMNKKGD_00580 7e-37
HKMNKKGD_00581 8.2e-48
HKMNKKGD_00582 1.2e-112 pgm8 G Histidine phosphatase superfamily (branch 1)
HKMNKKGD_00583 8.4e-63 S Domain of unknown function (DUF4440)
HKMNKKGD_00584 1.9e-158 K LysR substrate binding domain
HKMNKKGD_00585 1.2e-103 GM NAD(P)H-binding
HKMNKKGD_00586 2.3e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HKMNKKGD_00587 3.2e-150 IQ Enoyl-(Acyl carrier protein) reductase
HKMNKKGD_00588 1.1e-142 aRA11 1.1.1.346 S reductase
HKMNKKGD_00589 1.3e-81 yiiE S Protein of unknown function (DUF1211)
HKMNKKGD_00590 2.5e-76 darA C Flavodoxin
HKMNKKGD_00591 3e-126 IQ reductase
HKMNKKGD_00592 4.9e-82 glcU U sugar transport
HKMNKKGD_00593 1.1e-86 GM NAD(P)H-binding
HKMNKKGD_00594 5.6e-105 akr5f 1.1.1.346 S reductase
HKMNKKGD_00595 2e-78 K Transcriptional regulator
HKMNKKGD_00597 3e-25 fldA C Flavodoxin
HKMNKKGD_00598 4.4e-10 adhR K helix_turn_helix, mercury resistance
HKMNKKGD_00599 2.5e-114 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKMNKKGD_00600 1.3e-130 C Aldo keto reductase
HKMNKKGD_00601 1.5e-142 akr5f 1.1.1.346 S reductase
HKMNKKGD_00602 1.3e-142 EGP Major Facilitator Superfamily
HKMNKKGD_00603 5.7e-83 GM NAD(P)H-binding
HKMNKKGD_00604 6.1e-76 T Belongs to the universal stress protein A family
HKMNKKGD_00605 5.8e-95 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HKMNKKGD_00606 8.9e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HKMNKKGD_00607 1.7e-62
HKMNKKGD_00608 9.2e-104 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HKMNKKGD_00609 4.8e-221 patB 4.4.1.8 E Aminotransferase, class I
HKMNKKGD_00610 1.9e-102 M Protein of unknown function (DUF3737)
HKMNKKGD_00611 5.7e-194 C Aldo/keto reductase family
HKMNKKGD_00613 0.0 mdlB V ABC transporter
HKMNKKGD_00614 0.0 mdlA V ABC transporter
HKMNKKGD_00615 3.3e-245 EGP Major facilitator Superfamily
HKMNKKGD_00616 1.6e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKMNKKGD_00618 9.7e-194 yhgE V domain protein
HKMNKKGD_00619 5.1e-96 K Transcriptional regulator (TetR family)
HKMNKKGD_00620 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
HKMNKKGD_00621 6.3e-139 endA F DNA RNA non-specific endonuclease
HKMNKKGD_00622 1.4e-98 speG J Acetyltransferase (GNAT) domain
HKMNKKGD_00623 1.1e-95 2.3.1.128 J Acetyltransferase (GNAT) domain
HKMNKKGD_00624 1e-132 2.7.1.89 M Phosphotransferase enzyme family
HKMNKKGD_00625 1.2e-219 S CAAX protease self-immunity
HKMNKKGD_00626 1.2e-307 ybiT S ABC transporter, ATP-binding protein
HKMNKKGD_00627 5.3e-147 3.1.3.102, 3.1.3.104 S hydrolase
HKMNKKGD_00628 0.0 S Predicted membrane protein (DUF2207)
HKMNKKGD_00629 0.0 uvrA3 L excinuclease ABC
HKMNKKGD_00630 4.2e-204 EGP Major facilitator Superfamily
HKMNKKGD_00631 7.6e-174 ropB K Helix-turn-helix XRE-family like proteins
HKMNKKGD_00632 1.1e-177 pepR1 3.4.11.5 I Releases the N-terminal proline from various substrates
HKMNKKGD_00633 9.8e-250 puuP_1 E Amino acid permease
HKMNKKGD_00634 9.9e-233 yxiO S Vacuole effluxer Atg22 like
HKMNKKGD_00635 3.6e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
HKMNKKGD_00636 1.3e-159 I alpha/beta hydrolase fold
HKMNKKGD_00637 1.1e-130 treR K UTRA
HKMNKKGD_00638 1.9e-238
HKMNKKGD_00639 5.6e-39 S Cytochrome B5
HKMNKKGD_00640 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKMNKKGD_00641 8.3e-142 2.7.7.65 T Diguanylate cyclase, GGDEF domain
HKMNKKGD_00642 6.9e-22 2.7.7.65 T Diguanylate cyclase, GGDEF domain
HKMNKKGD_00643 4.1e-21 2.7.7.65 T Diguanylate cyclase, GGDEF domain
HKMNKKGD_00644 6.8e-127 yliE T EAL domain
HKMNKKGD_00645 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKMNKKGD_00646 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HKMNKKGD_00647 2e-80
HKMNKKGD_00648 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKMNKKGD_00649 6.8e-192 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKMNKKGD_00650 1.5e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKMNKKGD_00651 4.9e-22
HKMNKKGD_00652 1.3e-78
HKMNKKGD_00653 2.2e-165 K LysR substrate binding domain
HKMNKKGD_00654 4e-243 P Sodium:sulfate symporter transmembrane region
HKMNKKGD_00655 1.1e-286 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HKMNKKGD_00656 7.4e-264 S response to antibiotic
HKMNKKGD_00657 8.2e-134 S zinc-ribbon domain
HKMNKKGD_00659 3.2e-37
HKMNKKGD_00660 3.9e-114 aroD S Alpha/beta hydrolase family
HKMNKKGD_00661 9.8e-176 S Phosphotransferase system, EIIC
HKMNKKGD_00662 4.8e-268 I acetylesterase activity
HKMNKKGD_00663 3.3e-224 sdrF M Collagen binding domain
HKMNKKGD_00664 6.9e-159 yicL EG EamA-like transporter family
HKMNKKGD_00665 4.4e-129 E lipolytic protein G-D-S-L family
HKMNKKGD_00666 1.1e-177 4.1.1.52 S Amidohydrolase
HKMNKKGD_00667 2.1e-111 K Transcriptional regulator C-terminal region
HKMNKKGD_00668 1.4e-47 3.6.4.12 K HxlR-like helix-turn-helix
HKMNKKGD_00669 1.1e-161 ypbG 2.7.1.2 GK ROK family
HKMNKKGD_00670 0.0 lmrA 3.6.3.44 V ABC transporter
HKMNKKGD_00671 1.1e-95 rmaB K Transcriptional regulator, MarR family
HKMNKKGD_00672 1.3e-119 drgA C Nitroreductase family
HKMNKKGD_00673 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HKMNKKGD_00674 9e-119 cmpC S ATPases associated with a variety of cellular activities
HKMNKKGD_00675 8.7e-155 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HKMNKKGD_00676 3.5e-169 XK27_00670 S ABC transporter
HKMNKKGD_00677 4.7e-261
HKMNKKGD_00678 2.3e-63
HKMNKKGD_00679 5.1e-190 S Cell surface protein
HKMNKKGD_00680 1e-91 S WxL domain surface cell wall-binding
HKMNKKGD_00681 2.4e-97 acuB S Domain in cystathionine beta-synthase and other proteins.
HKMNKKGD_00682 7.3e-124 livF E ABC transporter
HKMNKKGD_00683 1.8e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
HKMNKKGD_00684 1.5e-140 livM E Branched-chain amino acid transport system / permease component
HKMNKKGD_00685 6.5e-154 livH U Branched-chain amino acid transport system / permease component
HKMNKKGD_00686 2.7e-211 livJ E Receptor family ligand binding region
HKMNKKGD_00688 1.6e-123 L PFAM transposase IS116 IS110 IS902 family
HKMNKKGD_00689 7e-33
HKMNKKGD_00690 5e-113 zmp3 O Zinc-dependent metalloprotease
HKMNKKGD_00691 2.8e-82 gtrA S GtrA-like protein
HKMNKKGD_00692 3.2e-121 K Helix-turn-helix XRE-family like proteins
HKMNKKGD_00693 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
HKMNKKGD_00694 6.8e-72 T Belongs to the universal stress protein A family
HKMNKKGD_00695 1.1e-46
HKMNKKGD_00696 1.9e-116 S SNARE associated Golgi protein
HKMNKKGD_00697 2e-49 K Transcriptional regulator, ArsR family
HKMNKKGD_00698 7.5e-95 cadD P Cadmium resistance transporter
HKMNKKGD_00699 0.0 yhcA V ABC transporter, ATP-binding protein
HKMNKKGD_00700 0.0 P Concanavalin A-like lectin/glucanases superfamily
HKMNKKGD_00701 7.4e-64
HKMNKKGD_00702 3.4e-160 T Calcineurin-like phosphoesterase superfamily domain
HKMNKKGD_00703 3.2e-55
HKMNKKGD_00704 5.3e-150 dicA K Helix-turn-helix domain
HKMNKKGD_00705 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKMNKKGD_00706 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HKMNKKGD_00707 2.7e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKMNKKGD_00708 2.4e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKMNKKGD_00709 4.4e-186 1.1.1.219 GM Male sterility protein
HKMNKKGD_00710 5.1e-75 K helix_turn_helix, mercury resistance
HKMNKKGD_00711 8.1e-63 M LysM domain
HKMNKKGD_00712 2.2e-93 M Lysin motif
HKMNKKGD_00713 4.7e-108 S SdpI/YhfL protein family
HKMNKKGD_00714 1.8e-54 nudA S ASCH
HKMNKKGD_00715 1.2e-163 psaA P Belongs to the bacterial solute-binding protein 9 family
HKMNKKGD_00716 2.7e-91
HKMNKKGD_00717 7.6e-120 tag 3.2.2.20 L Methyladenine glycosylase
HKMNKKGD_00718 9.7e-219 T diguanylate cyclase
HKMNKKGD_00719 1.2e-73 S Psort location Cytoplasmic, score
HKMNKKGD_00720 2.1e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HKMNKKGD_00721 2.6e-166 K Bacterial regulatory helix-turn-helix protein, lysR family
HKMNKKGD_00722 2.7e-70
HKMNKKGD_00723 3.8e-131 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKMNKKGD_00724 7.4e-176 C C4-dicarboxylate transmembrane transporter activity
HKMNKKGD_00725 1.6e-117 GM NAD(P)H-binding
HKMNKKGD_00726 4.7e-93 S Phosphatidylethanolamine-binding protein
HKMNKKGD_00727 2.7e-78 yphH S Cupin domain
HKMNKKGD_00728 3.7e-60 I sulfurtransferase activity
HKMNKKGD_00729 6.6e-139 IQ reductase
HKMNKKGD_00730 3.6e-117 GM NAD(P)H-binding
HKMNKKGD_00731 1.9e-217 ykiI
HKMNKKGD_00732 0.0 V ABC transporter
HKMNKKGD_00733 4.8e-311 XK27_09600 V ABC transporter, ATP-binding protein
HKMNKKGD_00734 9.1e-177 O protein import
HKMNKKGD_00735 7.8e-227 amd 3.5.1.47 E Peptidase family M20/M25/M40
HKMNKKGD_00736 7.7e-163 IQ KR domain
HKMNKKGD_00738 2.5e-71
HKMNKKGD_00739 1e-145 K Helix-turn-helix XRE-family like proteins
HKMNKKGD_00740 9.6e-267 yjeM E Amino Acid
HKMNKKGD_00741 1.3e-66 lysM M LysM domain
HKMNKKGD_00742 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HKMNKKGD_00743 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HKMNKKGD_00744 0.0 ctpA 3.6.3.54 P P-type ATPase
HKMNKKGD_00745 1.2e-42 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HKMNKKGD_00746 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HKMNKKGD_00747 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HKMNKKGD_00748 6e-140 K Helix-turn-helix domain
HKMNKKGD_00749 2.9e-38 S TfoX C-terminal domain
HKMNKKGD_00750 3.5e-228 hpk9 2.7.13.3 T GHKL domain
HKMNKKGD_00751 1.6e-261
HKMNKKGD_00752 1.3e-75
HKMNKKGD_00753 9.2e-187 S Cell surface protein
HKMNKKGD_00754 1.7e-101 S WxL domain surface cell wall-binding
HKMNKKGD_00755 1.7e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
HKMNKKGD_00756 9.3e-68 S Iron-sulphur cluster biosynthesis
HKMNKKGD_00757 6.5e-116 S GyrI-like small molecule binding domain
HKMNKKGD_00758 1.6e-188 S Cell surface protein
HKMNKKGD_00760 7.5e-101 S WxL domain surface cell wall-binding
HKMNKKGD_00761 1.1e-62
HKMNKKGD_00762 3.9e-213 NU Mycoplasma protein of unknown function, DUF285
HKMNKKGD_00763 2.3e-116
HKMNKKGD_00764 1.5e-115 S Haloacid dehalogenase-like hydrolase
HKMNKKGD_00765 4.7e-57 K Transcriptional regulator PadR-like family
HKMNKKGD_00766 3e-119 M1-1017
HKMNKKGD_00767 2e-61 K Transcriptional regulator, HxlR family
HKMNKKGD_00768 4.9e-213 ytbD EGP Major facilitator Superfamily
HKMNKKGD_00769 3.2e-94 M ErfK YbiS YcfS YnhG
HKMNKKGD_00770 0.0 asnB 6.3.5.4 E Asparagine synthase
HKMNKKGD_00771 5.7e-135 K LytTr DNA-binding domain
HKMNKKGD_00772 3e-205 2.7.13.3 T GHKL domain
HKMNKKGD_00773 1.8e-99 fadR K Bacterial regulatory proteins, tetR family
HKMNKKGD_00774 2.8e-168 GM NmrA-like family
HKMNKKGD_00775 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HKMNKKGD_00776 0.0 M Glycosyl hydrolases family 25
HKMNKKGD_00777 1e-47 S Domain of unknown function (DUF1905)
HKMNKKGD_00778 3.7e-63 hxlR K HxlR-like helix-turn-helix
HKMNKKGD_00779 2.2e-131 ydfG S KR domain
HKMNKKGD_00780 3.2e-98 K Bacterial regulatory proteins, tetR family
HKMNKKGD_00781 3.5e-191 1.1.1.219 GM Male sterility protein
HKMNKKGD_00782 4.1e-101 S Protein of unknown function (DUF1211)
HKMNKKGD_00783 1.5e-180 S Aldo keto reductase
HKMNKKGD_00784 4.7e-250 yfjF U Sugar (and other) transporter
HKMNKKGD_00785 7.4e-109 K Bacterial regulatory proteins, tetR family
HKMNKKGD_00786 4.4e-169 fhuD P Periplasmic binding protein
HKMNKKGD_00787 4.2e-144 fhuC 3.6.3.34 HP ABC transporter
HKMNKKGD_00788 9.5e-178 sirB U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKMNKKGD_00789 1e-171 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKMNKKGD_00790 5.4e-92 K Bacterial regulatory proteins, tetR family
HKMNKKGD_00791 4.1e-164 GM NmrA-like family
HKMNKKGD_00792 1.1e-30 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HKMNKKGD_00793 1.2e-160 yceJ EGP Major facilitator Superfamily
HKMNKKGD_00794 1.6e-129 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKMNKKGD_00795 1.6e-68 maa S transferase hexapeptide repeat
HKMNKKGD_00796 1.1e-147 IQ Enoyl-(Acyl carrier protein) reductase
HKMNKKGD_00797 2.3e-63 K helix_turn_helix, mercury resistance
HKMNKKGD_00798 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HKMNKKGD_00799 3e-174 S Bacterial protein of unknown function (DUF916)
HKMNKKGD_00800 3.2e-85 S WxL domain surface cell wall-binding
HKMNKKGD_00801 3.2e-157 NU Mycoplasma protein of unknown function, DUF285
HKMNKKGD_00802 8.5e-09 NU Mycoplasma protein of unknown function, DUF285
HKMNKKGD_00803 1.4e-116 K Bacterial regulatory proteins, tetR family
HKMNKKGD_00804 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKMNKKGD_00805 6.6e-290 yjcE P Sodium proton antiporter
HKMNKKGD_00806 4.3e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HKMNKKGD_00807 7.9e-163 K LysR substrate binding domain
HKMNKKGD_00808 1.6e-282 1.3.5.4 C FAD binding domain
HKMNKKGD_00809 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
HKMNKKGD_00811 1.7e-84 dps P Belongs to the Dps family
HKMNKKGD_00812 2.2e-115 K UTRA
HKMNKKGD_00813 1.2e-269 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKMNKKGD_00814 1.2e-247 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKMNKKGD_00815 1.3e-63
HKMNKKGD_00816 1.5e-11
HKMNKKGD_00817 9.4e-41 4.1.1.44 S Carboxymuconolactone decarboxylase family
HKMNKKGD_00818 2.2e-23 rmeD K helix_turn_helix, mercury resistance
HKMNKKGD_00819 2.9e-63 S Protein of unknown function (DUF1093)
HKMNKKGD_00820 1.5e-207 S Membrane
HKMNKKGD_00821 1.1e-43 S Protein of unknown function (DUF3781)
HKMNKKGD_00822 4e-107 ydeA S intracellular protease amidase
HKMNKKGD_00823 8.3e-41 K HxlR-like helix-turn-helix
HKMNKKGD_00824 3.3e-66
HKMNKKGD_00825 1.3e-64 V ABC transporter
HKMNKKGD_00826 2.3e-51 K Helix-turn-helix domain
HKMNKKGD_00827 3.8e-204 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HKMNKKGD_00828 5e-83 3.2.1.17, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKMNKKGD_00829 1.2e-104 M ErfK YbiS YcfS YnhG
HKMNKKGD_00830 2.3e-111 akr5f 1.1.1.346 S reductase
HKMNKKGD_00831 3.7e-108 GM NAD(P)H-binding
HKMNKKGD_00832 3.2e-77 3.5.4.1 GM SnoaL-like domain
HKMNKKGD_00833 7.9e-258 qacA EGP Fungal trichothecene efflux pump (TRI12)
HKMNKKGD_00834 9.2e-65 S Domain of unknown function (DUF4440)
HKMNKKGD_00835 9.1e-104 K Bacterial regulatory proteins, tetR family
HKMNKKGD_00836 2.3e-19 L HTH-like domain
HKMNKKGD_00837 3.6e-32 L Integrase core domain
HKMNKKGD_00839 6.8e-33 L transposase activity
HKMNKKGD_00841 4.1e-07 mesE U HlyD family secretion protein
HKMNKKGD_00843 5.9e-41 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HKMNKKGD_00844 1.4e-32 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKMNKKGD_00845 4e-28 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HKMNKKGD_00846 1.8e-203 G system Galactitol-specific IIC component
HKMNKKGD_00847 2.1e-70 rpiB 5.3.1.26, 5.3.1.34, 5.3.1.6 G Ribose/Galactose Isomerase
HKMNKKGD_00848 9.3e-69 fruR K DeoR C terminal sensor domain
HKMNKKGD_00849 3.2e-93 IQ Enoyl-(Acyl carrier protein) reductase
HKMNKKGD_00850 1.7e-59 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HKMNKKGD_00851 3.6e-85 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HKMNKKGD_00852 2.1e-166 G system Galactitol-specific IIC component
HKMNKKGD_00853 3.9e-26 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HKMNKKGD_00854 5.5e-43 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKMNKKGD_00855 4.2e-172 2.7.1.194, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKMNKKGD_00856 3.3e-39 GM NAD(P)H-binding
HKMNKKGD_00857 6.4e-35
HKMNKKGD_00858 5.1e-112 Q Methyltransferase domain
HKMNKKGD_00859 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKMNKKGD_00860 1.9e-171 K AI-2E family transporter
HKMNKKGD_00861 2.4e-190 xylR GK ROK family
HKMNKKGD_00862 1.7e-81
HKMNKKGD_00863 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HKMNKKGD_00864 1e-162
HKMNKKGD_00865 5e-201 KLT Protein tyrosine kinase
HKMNKKGD_00866 2.9e-23 S Protein of unknown function (DUF4064)
HKMNKKGD_00867 6e-97 S Domain of unknown function (DUF4352)
HKMNKKGD_00868 3.9e-75 S Psort location Cytoplasmic, score
HKMNKKGD_00869 4.1e-54
HKMNKKGD_00870 3.6e-110 S membrane transporter protein
HKMNKKGD_00871 2.3e-54 azlD S branched-chain amino acid
HKMNKKGD_00872 5.1e-131 azlC E branched-chain amino acid
HKMNKKGD_00873 1.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HKMNKKGD_00874 4.9e-238 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKMNKKGD_00875 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
HKMNKKGD_00876 3.2e-124 K response regulator
HKMNKKGD_00877 5.5e-124 yoaK S Protein of unknown function (DUF1275)
HKMNKKGD_00878 2.9e-160 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKMNKKGD_00879 2.3e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKMNKKGD_00880 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
HKMNKKGD_00881 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKMNKKGD_00882 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
HKMNKKGD_00883 6.3e-157 spo0J K Belongs to the ParB family
HKMNKKGD_00884 1.8e-136 soj D Sporulation initiation inhibitor
HKMNKKGD_00885 2.7e-149 noc K Belongs to the ParB family
HKMNKKGD_00886 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HKMNKKGD_00887 4.1e-226 nupG F Nucleoside
HKMNKKGD_00888 0.0 S Bacterial membrane protein YfhO
HKMNKKGD_00889 3e-145 S Alpha/beta hydrolase of unknown function (DUF915)
HKMNKKGD_00890 6.1e-168 K LysR substrate binding domain
HKMNKKGD_00891 2.1e-235 EK Aminotransferase, class I
HKMNKKGD_00892 1.8e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HKMNKKGD_00893 8.1e-123 tcyB E ABC transporter
HKMNKKGD_00894 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKMNKKGD_00895 4.3e-128 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HKMNKKGD_00896 1.1e-77 KT response to antibiotic
HKMNKKGD_00897 1.5e-52 K Transcriptional regulator
HKMNKKGD_00898 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
HKMNKKGD_00899 1.7e-128 S Putative adhesin
HKMNKKGD_00900 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
HKMNKKGD_00901 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HKMNKKGD_00902 1.4e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HKMNKKGD_00903 1.3e-204 S DUF218 domain
HKMNKKGD_00904 2e-127 ybbM S Uncharacterised protein family (UPF0014)
HKMNKKGD_00905 3.6e-117 ybbL S ABC transporter, ATP-binding protein
HKMNKKGD_00906 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKMNKKGD_00907 9.4e-77
HKMNKKGD_00908 2.2e-151 qorB 1.6.5.2 GM NmrA-like family
HKMNKKGD_00909 1.1e-147 cof S haloacid dehalogenase-like hydrolase
HKMNKKGD_00910 6e-79 merR K MerR family regulatory protein
HKMNKKGD_00911 2.6e-155 1.6.5.2 GM NmrA-like family
HKMNKKGD_00912 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HKMNKKGD_00913 1.1e-126 magIII L Base excision DNA repair protein, HhH-GPD family
HKMNKKGD_00914 1.4e-08
HKMNKKGD_00915 2e-100 S NADPH-dependent FMN reductase
HKMNKKGD_00916 3e-237 S module of peptide synthetase
HKMNKKGD_00917 2.5e-104
HKMNKKGD_00918 9.8e-88 perR P Belongs to the Fur family
HKMNKKGD_00919 2.1e-58 S Enterocin A Immunity
HKMNKKGD_00920 5.4e-36 S Phospholipase_D-nuclease N-terminal
HKMNKKGD_00921 1.8e-169 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
HKMNKKGD_00922 3.8e-104 J Acetyltransferase (GNAT) domain
HKMNKKGD_00923 5.1e-64 lrgA S LrgA family
HKMNKKGD_00924 7.3e-127 lrgB M LrgB-like family
HKMNKKGD_00925 2.5e-145 DegV S EDD domain protein, DegV family
HKMNKKGD_00926 4.1e-25
HKMNKKGD_00927 3.5e-118 yugP S Putative neutral zinc metallopeptidase
HKMNKKGD_00928 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
HKMNKKGD_00929 7.4e-166 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
HKMNKKGD_00930 1.7e-184 D Alpha beta
HKMNKKGD_00931 7.1e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HKMNKKGD_00932 8.1e-257 gor 1.8.1.7 C Glutathione reductase
HKMNKKGD_00933 3.4e-55 S Enterocin A Immunity
HKMNKKGD_00934 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKMNKKGD_00935 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKMNKKGD_00936 3.5e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKMNKKGD_00937 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
HKMNKKGD_00938 4.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKMNKKGD_00940 6.2e-82
HKMNKKGD_00941 1.5e-256 yhdG E C-terminus of AA_permease
HKMNKKGD_00943 0.0 kup P Transport of potassium into the cell
HKMNKKGD_00944 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKMNKKGD_00945 3.1e-179 K AI-2E family transporter
HKMNKKGD_00946 4e-217 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HKMNKKGD_00947 4.4e-59 qacC P Small Multidrug Resistance protein
HKMNKKGD_00948 1.1e-44 qacH U Small Multidrug Resistance protein
HKMNKKGD_00949 3e-116 hly S protein, hemolysin III
HKMNKKGD_00950 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HKMNKKGD_00951 1.8e-159 czcD P cation diffusion facilitator family transporter
HKMNKKGD_00952 7.8e-103 K Helix-turn-helix XRE-family like proteins
HKMNKKGD_00954 2.6e-19
HKMNKKGD_00955 1.5e-95 tag 3.2.2.20 L glycosylase
HKMNKKGD_00956 6.8e-212 folP 2.5.1.15 H dihydropteroate synthase
HKMNKKGD_00957 7.2e-101 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HKMNKKGD_00958 1.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HKMNKKGD_00959 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HKMNKKGD_00960 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HKMNKKGD_00961 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKMNKKGD_00962 4.7e-83 cvpA S Colicin V production protein
HKMNKKGD_00963 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
HKMNKKGD_00964 1.3e-249 EGP Major facilitator Superfamily
HKMNKKGD_00966 1.2e-39
HKMNKKGD_00967 1.5e-42 S COG NOG38524 non supervised orthologous group
HKMNKKGD_00968 1.4e-95 V VanZ like family
HKMNKKGD_00969 5e-195 blaA6 V Beta-lactamase
HKMNKKGD_00970 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HKMNKKGD_00971 6.7e-161 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKMNKKGD_00972 5.1e-53 yitW S Pfam:DUF59
HKMNKKGD_00973 5.9e-174 S Aldo keto reductase
HKMNKKGD_00974 3.3e-97 FG HIT domain
HKMNKKGD_00975 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
HKMNKKGD_00976 1.4e-77
HKMNKKGD_00977 6.2e-122 E GDSL-like Lipase/Acylhydrolase family
HKMNKKGD_00978 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
HKMNKKGD_00979 0.0 cadA P P-type ATPase
HKMNKKGD_00981 5.4e-121 yyaQ S YjbR
HKMNKKGD_00982 1.6e-123 L PFAM transposase IS116 IS110 IS902 family
HKMNKKGD_00983 1.3e-221 S Uncharacterized protein conserved in bacteria (DUF2325)
HKMNKKGD_00984 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HKMNKKGD_00985 1.3e-199 frlB M SIS domain
HKMNKKGD_00986 6.1e-27 3.2.2.10 S Belongs to the LOG family
HKMNKKGD_00987 1.4e-254 nhaC C Na H antiporter NhaC
HKMNKKGD_00988 2.4e-251 cycA E Amino acid permease
HKMNKKGD_00989 2.4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HKMNKKGD_00990 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HKMNKKGD_00991 4.8e-162 azoB GM NmrA-like family
HKMNKKGD_00992 1.6e-65 K Winged helix DNA-binding domain
HKMNKKGD_00993 7e-71 spx4 1.20.4.1 P ArsC family
HKMNKKGD_00994 1.7e-66 yeaO S Protein of unknown function, DUF488
HKMNKKGD_00995 4e-53
HKMNKKGD_00996 4.1e-214 mutY L A G-specific adenine glycosylase
HKMNKKGD_00997 1.9e-62
HKMNKKGD_00998 4.3e-86
HKMNKKGD_00999 4.5e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
HKMNKKGD_01000 7e-56
HKMNKKGD_01001 2.1e-14
HKMNKKGD_01002 1.1e-115 GM NmrA-like family
HKMNKKGD_01003 1.3e-81 elaA S GNAT family
HKMNKKGD_01004 1.6e-158 EG EamA-like transporter family
HKMNKKGD_01005 1.8e-119 S membrane
HKMNKKGD_01006 1.4e-111 S VIT family
HKMNKKGD_01007 4.8e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HKMNKKGD_01008 0.0 copB 3.6.3.4 P P-type ATPase
HKMNKKGD_01009 9.4e-74 copR K Copper transport repressor CopY TcrY
HKMNKKGD_01010 7.4e-40
HKMNKKGD_01011 1.2e-73 S COG NOG18757 non supervised orthologous group
HKMNKKGD_01012 1.5e-248 lmrB EGP Major facilitator Superfamily
HKMNKKGD_01013 1.7e-24
HKMNKKGD_01014 4.2e-49
HKMNKKGD_01015 1.6e-64 ycgX S Protein of unknown function (DUF1398)
HKMNKKGD_01016 2.3e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HKMNKKGD_01017 5.9e-214 mdtG EGP Major facilitator Superfamily
HKMNKKGD_01018 6.8e-181 D Alpha beta
HKMNKKGD_01019 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
HKMNKKGD_01020 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HKMNKKGD_01021 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HKMNKKGD_01022 2.1e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HKMNKKGD_01023 3.8e-152 ywkB S Membrane transport protein
HKMNKKGD_01024 5.2e-164 yvgN C Aldo keto reductase
HKMNKKGD_01025 9.2e-133 thrE S Putative threonine/serine exporter
HKMNKKGD_01026 2e-77 S Threonine/Serine exporter, ThrE
HKMNKKGD_01027 2.3e-43 S Protein of unknown function (DUF1093)
HKMNKKGD_01028 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKMNKKGD_01029 1e-90 ymdB S Macro domain protein
HKMNKKGD_01030 3.4e-95 K transcriptional regulator
HKMNKKGD_01031 5.5e-50 yvlA
HKMNKKGD_01032 6e-161 ypuA S Protein of unknown function (DUF1002)
HKMNKKGD_01033 0.0
HKMNKKGD_01034 5.8e-186 S Bacterial protein of unknown function (DUF916)
HKMNKKGD_01035 1.7e-129 S WxL domain surface cell wall-binding
HKMNKKGD_01036 1.9e-135 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HKMNKKGD_01037 3.5e-88 K Winged helix DNA-binding domain
HKMNKKGD_01038 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
HKMNKKGD_01039 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HKMNKKGD_01040 1.8e-27
HKMNKKGD_01041 2.5e-285 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HKMNKKGD_01042 1.6e-74 mltD CBM50 M PFAM NLP P60 protein
HKMNKKGD_01043 3.3e-50
HKMNKKGD_01044 3.5e-61
HKMNKKGD_01047 9.4e-183 yfeX P Peroxidase
HKMNKKGD_01048 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKMNKKGD_01049 2.4e-127 ydcF S Gram-negative-bacterium-type cell wall biogenesis
HKMNKKGD_01050 1.5e-183 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HKMNKKGD_01051 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HKMNKKGD_01052 2.4e-141 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HKMNKKGD_01053 9.5e-55 txlA O Thioredoxin-like domain
HKMNKKGD_01054 5.6e-40 yrkD S Metal-sensitive transcriptional repressor
HKMNKKGD_01055 1.6e-18
HKMNKKGD_01056 1.2e-94 dps P Belongs to the Dps family
HKMNKKGD_01057 1.6e-32 copZ P Heavy-metal-associated domain
HKMNKKGD_01058 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HKMNKKGD_01059 0.0 pepO 3.4.24.71 O Peptidase family M13
HKMNKKGD_01060 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKMNKKGD_01061 1.3e-262 nox C NADH oxidase
HKMNKKGD_01062 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HKMNKKGD_01063 6.1e-164 S Cell surface protein
HKMNKKGD_01064 1.5e-118 S WxL domain surface cell wall-binding
HKMNKKGD_01065 2.3e-99 S WxL domain surface cell wall-binding
HKMNKKGD_01066 2.3e-44
HKMNKKGD_01067 5.4e-104 K Bacterial regulatory proteins, tetR family
HKMNKKGD_01068 1.5e-49
HKMNKKGD_01069 1.4e-248 S Putative metallopeptidase domain
HKMNKKGD_01070 2.4e-220 3.1.3.1 S associated with various cellular activities
HKMNKKGD_01071 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
HKMNKKGD_01072 0.0 ubiB S ABC1 family
HKMNKKGD_01073 1.3e-249 brnQ U Component of the transport system for branched-chain amino acids
HKMNKKGD_01074 0.0 lacS G Transporter
HKMNKKGD_01075 0.0 lacA 3.2.1.23 G -beta-galactosidase
HKMNKKGD_01076 1.6e-188 lacR K Transcriptional regulator
HKMNKKGD_01077 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HKMNKKGD_01078 3.6e-230 mdtH P Sugar (and other) transporter
HKMNKKGD_01079 5.2e-303 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HKMNKKGD_01080 8.6e-232 EGP Major facilitator Superfamily
HKMNKKGD_01081 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
HKMNKKGD_01082 5e-100 fic D Fic/DOC family
HKMNKKGD_01083 4.7e-76 K Helix-turn-helix XRE-family like proteins
HKMNKKGD_01084 2e-183 galR K Transcriptional regulator
HKMNKKGD_01085 1.9e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HKMNKKGD_01086 8.9e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HKMNKKGD_01087 9.3e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKMNKKGD_01088 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HKMNKKGD_01089 8.3e-187 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HKMNKKGD_01090 0.0 rafA 3.2.1.22 G alpha-galactosidase
HKMNKKGD_01091 0.0 lacS G Transporter
HKMNKKGD_01092 4.2e-197 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HKMNKKGD_01093 1.1e-173 galR K Transcriptional regulator
HKMNKKGD_01094 2.6e-194 C Aldo keto reductase family protein
HKMNKKGD_01095 2.4e-65 S pyridoxamine 5-phosphate
HKMNKKGD_01096 0.0 1.3.5.4 C FAD binding domain
HKMNKKGD_01097 1.2e-172 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKMNKKGD_01098 1.1e-130 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HKMNKKGD_01099 1.2e-214 ydiM G Transporter
HKMNKKGD_01100 4.2e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKMNKKGD_01101 2.9e-162 K Transcriptional regulator, LysR family
HKMNKKGD_01102 6.7e-210 ydiN G Major Facilitator Superfamily
HKMNKKGD_01103 7.6e-64
HKMNKKGD_01104 1.8e-155 estA S Putative esterase
HKMNKKGD_01105 1.2e-134 K UTRA domain
HKMNKKGD_01106 3.6e-249 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKMNKKGD_01107 3e-165 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKMNKKGD_01108 1.9e-161 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HKMNKKGD_01109 1.7e-212 S Bacterial protein of unknown function (DUF871)
HKMNKKGD_01110 1e-292 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKMNKKGD_01111 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
HKMNKKGD_01112 1.3e-154 licT K CAT RNA binding domain
HKMNKKGD_01113 3.4e-293 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKMNKKGD_01114 1.1e-09 namA 1.3.5.4 C NADH flavin oxidoreductases, Old Yellow Enzyme family
HKMNKKGD_01115 3.2e-25 ykhA 3.1.2.20 I Thioesterase superfamily
HKMNKKGD_01116 1.6e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKMNKKGD_01117 2.1e-110 6.2.1.3 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HKMNKKGD_01118 2.6e-39 ygcQ C Electron transfer flavoprotein FAD-binding domain
HKMNKKGD_01119 1.8e-22 fixA C Electron transfer flavoprotein domain
HKMNKKGD_01120 1.3e-149 I Acyl-CoA dehydrogenase, C-terminal domain
HKMNKKGD_01121 9.1e-170 MA20_04610 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HKMNKKGD_01122 3.6e-187 I Acyl-CoA dehydrogenase, N-terminal domain
HKMNKKGD_01123 1.5e-135 oxlT G Major Facilitator Superfamily
HKMNKKGD_01124 1.2e-65 K Transcriptional regulator, LysR family
HKMNKKGD_01125 1.9e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKMNKKGD_01126 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
HKMNKKGD_01127 3.8e-159 licT K CAT RNA binding domain
HKMNKKGD_01128 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
HKMNKKGD_01129 2.1e-174 K Transcriptional regulator, LacI family
HKMNKKGD_01130 6.1e-271 G Major Facilitator
HKMNKKGD_01131 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HKMNKKGD_01133 5.8e-188 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKMNKKGD_01134 2.7e-146 yxeH S hydrolase
HKMNKKGD_01135 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKMNKKGD_01136 2e-115 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKMNKKGD_01137 9.8e-242 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HKMNKKGD_01138 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
HKMNKKGD_01139 6.7e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKMNKKGD_01140 6.8e-234 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKMNKKGD_01141 6.5e-142 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKMNKKGD_01142 1.3e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
HKMNKKGD_01143 1.4e-187 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HKMNKKGD_01144 5.1e-113 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HKMNKKGD_01145 1.6e-193 gatC G PTS system sugar-specific permease component
HKMNKKGD_01146 2.3e-34 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HKMNKKGD_01147 9.7e-56 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKMNKKGD_01148 9.8e-90 K DeoR C terminal sensor domain
HKMNKKGD_01149 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HKMNKKGD_01150 2.6e-70 yueI S Protein of unknown function (DUF1694)
HKMNKKGD_01151 8.2e-102 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HKMNKKGD_01152 1.3e-265 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HKMNKKGD_01153 3.9e-136 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HKMNKKGD_01154 2.7e-307 araB 2.7.1.12, 2.7.1.16, 2.7.1.5 G carbohydrate kinase FGGY
HKMNKKGD_01155 1.6e-255 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKMNKKGD_01156 1.4e-206 araR K Transcriptional regulator
HKMNKKGD_01157 7.4e-136 K Helix-turn-helix domain, rpiR family
HKMNKKGD_01158 3.7e-72 yueI S Protein of unknown function (DUF1694)
HKMNKKGD_01159 1.3e-164 I alpha/beta hydrolase fold
HKMNKKGD_01160 1.5e-160 I alpha/beta hydrolase fold
HKMNKKGD_01161 2.6e-272 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKMNKKGD_01162 5.2e-207 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKMNKKGD_01163 1.9e-135 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
HKMNKKGD_01164 5.2e-156 nanK GK ROK family
HKMNKKGD_01165 6.2e-165 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HKMNKKGD_01166 9.3e-124 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HKMNKKGD_01167 2.1e-227 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
HKMNKKGD_01168 4.2e-70 S Pyrimidine dimer DNA glycosylase
HKMNKKGD_01169 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
HKMNKKGD_01170 3e-10
HKMNKKGD_01171 9e-13 ytgB S Transglycosylase associated protein
HKMNKKGD_01172 1.9e-291 katA 1.11.1.6 C Belongs to the catalase family
HKMNKKGD_01173 4.9e-78 yneH 1.20.4.1 K ArsC family
HKMNKKGD_01174 2.8e-134 K LytTr DNA-binding domain
HKMNKKGD_01175 8.7e-160 2.7.13.3 T GHKL domain
HKMNKKGD_01176 1.8e-12
HKMNKKGD_01177 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HKMNKKGD_01178 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
HKMNKKGD_01180 6.1e-202 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HKMNKKGD_01181 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HKMNKKGD_01182 8.7e-72 K Transcriptional regulator
HKMNKKGD_01183 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HKMNKKGD_01184 4.2e-71 yueI S Protein of unknown function (DUF1694)
HKMNKKGD_01185 1e-125 S Membrane
HKMNKKGD_01186 1.2e-165 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HKMNKKGD_01187 1.3e-256 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HKMNKKGD_01188 5e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HKMNKKGD_01189 1.8e-286 rhaB 2.7.1.12, 2.7.1.16, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HKMNKKGD_01190 4.6e-244 iolF EGP Major facilitator Superfamily
HKMNKKGD_01191 1.9e-178 rhaR K helix_turn_helix, arabinose operon control protein
HKMNKKGD_01192 2.1e-140 K DeoR C terminal sensor domain
HKMNKKGD_01193 4.2e-80 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKMNKKGD_01194 3.3e-52 sgcB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HKMNKKGD_01195 3.2e-249 pts36C G PTS system sugar-specific permease component
HKMNKKGD_01197 1.6e-134 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HKMNKKGD_01198 2.8e-260 iolT EGP Major facilitator Superfamily
HKMNKKGD_01199 1.7e-198 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HKMNKKGD_01200 7.6e-202 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HKMNKKGD_01201 5e-178 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HKMNKKGD_01202 4.2e-197 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HKMNKKGD_01203 5e-268 iolT EGP Major facilitator Superfamily
HKMNKKGD_01204 9.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HKMNKKGD_01205 7.8e-82 S Haem-degrading
HKMNKKGD_01206 2.1e-171 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
HKMNKKGD_01207 1.6e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKMNKKGD_01208 1.5e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HKMNKKGD_01209 1e-116 L PFAM Integrase, catalytic core
HKMNKKGD_01210 8.5e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HKMNKKGD_01211 6.5e-174 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HKMNKKGD_01212 6.3e-102 srlA G PTS system enzyme II sorbitol-specific factor
HKMNKKGD_01213 9.2e-92 gutM K Glucitol operon activator protein (GutM)
HKMNKKGD_01214 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HKMNKKGD_01215 5.5e-145 IQ NAD dependent epimerase/dehydratase family
HKMNKKGD_01216 5.9e-287 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKMNKKGD_01217 1.3e-159 ypbG 2.7.1.2 GK ROK family
HKMNKKGD_01218 0.0 mngB 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HKMNKKGD_01219 3.1e-253 S Metal-independent alpha-mannosidase (GH125)
HKMNKKGD_01220 2.7e-194 rliB K Transcriptional regulator
HKMNKKGD_01221 0.0 ypdD G Glycosyl hydrolase family 92
HKMNKKGD_01222 9.1e-217 msmX P Belongs to the ABC transporter superfamily
HKMNKKGD_01223 8e-165 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HKMNKKGD_01224 1.8e-270 yesN K helix_turn_helix, arabinose operon control protein
HKMNKKGD_01225 0.0 yesM 2.7.13.3 T Histidine kinase
HKMNKKGD_01226 4.1e-107 ypcB S integral membrane protein
HKMNKKGD_01227 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HKMNKKGD_01228 9.8e-280 G Domain of unknown function (DUF3502)
HKMNKKGD_01229 1.5e-161 lplC U Binding-protein-dependent transport system inner membrane component
HKMNKKGD_01230 5.2e-181 U Binding-protein-dependent transport system inner membrane component
HKMNKKGD_01231 0.0 3.2.1.52 GH20 G Glycosyl hydrolase family 20, catalytic domain
HKMNKKGD_01232 8.5e-156 K AraC-like ligand binding domain
HKMNKKGD_01233 0.0 mdlA2 V ABC transporter
HKMNKKGD_01234 0.0 yknV V ABC transporter
HKMNKKGD_01235 2.2e-193 rliB K helix_turn_helix gluconate operon transcriptional repressor
HKMNKKGD_01236 6.8e-156 lrp QT PucR C-terminal helix-turn-helix domain
HKMNKKGD_01237 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HKMNKKGD_01238 1e-174 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HKMNKKGD_01239 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
HKMNKKGD_01240 2.5e-86 gutM K Glucitol operon activator protein (GutM)
HKMNKKGD_01241 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HKMNKKGD_01242 1.5e-144 IQ NAD dependent epimerase/dehydratase family
HKMNKKGD_01243 2.7e-160 rbsU U ribose uptake protein RbsU
HKMNKKGD_01244 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKMNKKGD_01245 2.3e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKMNKKGD_01246 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
HKMNKKGD_01247 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HKMNKKGD_01248 2e-160 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKMNKKGD_01249 7.4e-26 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKMNKKGD_01250 2.7e-79 T Universal stress protein family
HKMNKKGD_01251 2.2e-99 padR K Virulence activator alpha C-term
HKMNKKGD_01252 1.7e-104 padC Q Phenolic acid decarboxylase
HKMNKKGD_01253 6.7e-142 tesE Q hydratase
HKMNKKGD_01254 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
HKMNKKGD_01255 1.2e-157 degV S DegV family
HKMNKKGD_01256 9.3e-58 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
HKMNKKGD_01257 1.5e-255 pepC 3.4.22.40 E aminopeptidase
HKMNKKGD_01259 3.6e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HKMNKKGD_01260 1.1e-302
HKMNKKGD_01262 1.2e-159 S Bacterial protein of unknown function (DUF916)
HKMNKKGD_01263 6.9e-93 S Cell surface protein
HKMNKKGD_01264 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKMNKKGD_01265 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKMNKKGD_01266 2.5e-130 jag S R3H domain protein
HKMNKKGD_01267 9.3e-239 Q Imidazolonepropionase and related amidohydrolases
HKMNKKGD_01268 7.7e-310 E ABC transporter, substratebinding protein
HKMNKKGD_01269 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKMNKKGD_01270 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKMNKKGD_01271 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKMNKKGD_01272 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKMNKKGD_01273 5e-37 yaaA S S4 domain protein YaaA
HKMNKKGD_01274 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKMNKKGD_01275 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKMNKKGD_01276 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKMNKKGD_01277 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HKMNKKGD_01278 6.8e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKMNKKGD_01279 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKMNKKGD_01280 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HKMNKKGD_01281 1.4e-67 rplI J Binds to the 23S rRNA
HKMNKKGD_01282 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HKMNKKGD_01283 8.8e-226 yttB EGP Major facilitator Superfamily
HKMNKKGD_01284 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKMNKKGD_01285 4.3e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKMNKKGD_01287 1.9e-276 E ABC transporter, substratebinding protein
HKMNKKGD_01289 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKMNKKGD_01290 9.4e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKMNKKGD_01291 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HKMNKKGD_01292 2.6e-277 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HKMNKKGD_01293 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKMNKKGD_01294 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HKMNKKGD_01296 6.5e-142 S haloacid dehalogenase-like hydrolase
HKMNKKGD_01297 3e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HKMNKKGD_01298 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
HKMNKKGD_01299 4e-197 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKMNKKGD_01300 7.6e-20 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKMNKKGD_01301 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
HKMNKKGD_01302 1.6e-31 cspA K Cold shock protein domain
HKMNKKGD_01303 1.7e-37
HKMNKKGD_01305 6.2e-131 K response regulator
HKMNKKGD_01306 0.0 vicK 2.7.13.3 T Histidine kinase
HKMNKKGD_01307 1.3e-243 yycH S YycH protein
HKMNKKGD_01308 6.5e-151 yycI S YycH protein
HKMNKKGD_01309 8.9e-158 vicX 3.1.26.11 S domain protein
HKMNKKGD_01310 6.8e-173 htrA 3.4.21.107 O serine protease
HKMNKKGD_01311 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKMNKKGD_01312 1.5e-95 K Bacterial regulatory proteins, tetR family
HKMNKKGD_01313 1.2e-261 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
HKMNKKGD_01314 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HKMNKKGD_01315 1.8e-92 pnb C nitroreductase
HKMNKKGD_01316 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HKMNKKGD_01317 1.8e-116 S Elongation factor G-binding protein, N-terminal
HKMNKKGD_01318 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
HKMNKKGD_01319 1.6e-258 P Sodium:sulfate symporter transmembrane region
HKMNKKGD_01320 5.7e-158 K LysR family
HKMNKKGD_01321 3e-72 C FMN binding
HKMNKKGD_01322 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKMNKKGD_01323 2.3e-164 ptlF S KR domain
HKMNKKGD_01324 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HKMNKKGD_01325 1.3e-122 drgA C Nitroreductase family
HKMNKKGD_01326 1e-292 QT PucR C-terminal helix-turn-helix domain
HKMNKKGD_01328 5.5e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HKMNKKGD_01329 6e-196 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKMNKKGD_01330 7.4e-250 yjjP S Putative threonine/serine exporter
HKMNKKGD_01331 5.7e-135 wzb 3.1.3.48 T Tyrosine phosphatase family
HKMNKKGD_01332 1.4e-254 1.14.14.9 Q 4-hydroxyphenylacetate
HKMNKKGD_01333 2.9e-81 6.3.3.2 S ASCH
HKMNKKGD_01334 4.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HKMNKKGD_01335 2e-169 yobV1 K WYL domain
HKMNKKGD_01336 3.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKMNKKGD_01337 0.0 tetP J elongation factor G
HKMNKKGD_01338 1.9e-29 S Protein of unknown function
HKMNKKGD_01339 8.3e-81 S Protein of unknown function
HKMNKKGD_01340 5e-154 EG EamA-like transporter family
HKMNKKGD_01341 3.6e-93 MA20_25245 K FR47-like protein
HKMNKKGD_01342 5.7e-126 hchA S DJ-1/PfpI family
HKMNKKGD_01343 1.6e-185 1.1.1.1 C nadph quinone reductase
HKMNKKGD_01344 1.9e-47 K helix_turn_helix, Arsenical Resistance Operon Repressor
HKMNKKGD_01345 8.7e-235 mepA V MATE efflux family protein
HKMNKKGD_01346 2.2e-167 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HKMNKKGD_01347 4.3e-136 S Belongs to the UPF0246 family
HKMNKKGD_01348 6e-76
HKMNKKGD_01349 1e-309 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
HKMNKKGD_01350 1.2e-140
HKMNKKGD_01352 7.2e-141 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HKMNKKGD_01353 4.8e-40
HKMNKKGD_01354 3.9e-128 cbiO P ABC transporter
HKMNKKGD_01355 2.6e-149 P Cobalt transport protein
HKMNKKGD_01356 4.8e-182 nikMN P PDGLE domain
HKMNKKGD_01357 4.2e-121 K Crp-like helix-turn-helix domain
HKMNKKGD_01358 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
HKMNKKGD_01359 5.3e-125 larB S AIR carboxylase
HKMNKKGD_01360 6.3e-132 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HKMNKKGD_01361 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
HKMNKKGD_01362 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HKMNKKGD_01363 2.8e-151 larE S NAD synthase
HKMNKKGD_01364 7.9e-177 1.6.5.5 C Zinc-binding dehydrogenase
HKMNKKGD_01365 8.4e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKMNKKGD_01366 1.1e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKMNKKGD_01367 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKMNKKGD_01368 5.3e-207 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HKMNKKGD_01369 1.6e-137 S peptidase C26
HKMNKKGD_01370 2.6e-302 L HIRAN domain
HKMNKKGD_01371 1.9e-83 F NUDIX domain
HKMNKKGD_01372 2.6e-250 yifK E Amino acid permease
HKMNKKGD_01373 0.0 L Transposase
HKMNKKGD_01374 1e-117
HKMNKKGD_01375 2.8e-148 ydjP I Alpha/beta hydrolase family
HKMNKKGD_01376 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HKMNKKGD_01377 6.4e-157 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKMNKKGD_01378 4.8e-48 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKMNKKGD_01379 1.6e-99 S CRISPR-associated protein (Cas_Csn2)
HKMNKKGD_01380 0.0 pacL1 P P-type ATPase
HKMNKKGD_01381 6.4e-142 2.4.2.3 F Phosphorylase superfamily
HKMNKKGD_01382 1.6e-28 KT PspC domain
HKMNKKGD_01383 3e-110 S NADPH-dependent FMN reductase
HKMNKKGD_01384 1.2e-74 papX3 K Transcriptional regulator
HKMNKKGD_01385 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
HKMNKKGD_01386 1.8e-53 S Protein of unknown function (DUF3021)
HKMNKKGD_01387 4.7e-227 mdtG EGP Major facilitator Superfamily
HKMNKKGD_01388 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HKMNKKGD_01389 8.1e-216 yeaN P Transporter, major facilitator family protein
HKMNKKGD_01391 4.9e-159 S reductase
HKMNKKGD_01392 1.2e-165 1.1.1.65 C Aldo keto reductase
HKMNKKGD_01393 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
HKMNKKGD_01394 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HKMNKKGD_01395 5e-52
HKMNKKGD_01396 7.5e-259
HKMNKKGD_01397 6.4e-207 C Oxidoreductase
HKMNKKGD_01398 1.7e-148 cbiQ P cobalt transport
HKMNKKGD_01399 0.0 ykoD P ABC transporter, ATP-binding protein
HKMNKKGD_01400 2.5e-98 S UPF0397 protein
HKMNKKGD_01402 1.6e-129 K UbiC transcription regulator-associated domain protein
HKMNKKGD_01403 8.3e-54 K Transcriptional regulator PadR-like family
HKMNKKGD_01404 1.7e-142
HKMNKKGD_01405 1.5e-149
HKMNKKGD_01406 9.1e-89
HKMNKKGD_01407 1.2e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HKMNKKGD_01408 6.7e-170 yjjC V ABC transporter
HKMNKKGD_01409 1.7e-296 M Exporter of polyketide antibiotics
HKMNKKGD_01410 3.4e-115 K Transcriptional regulator
HKMNKKGD_01411 4.4e-275 C Electron transfer flavoprotein FAD-binding domain
HKMNKKGD_01412 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
HKMNKKGD_01414 1.1e-92 K Bacterial regulatory proteins, tetR family
HKMNKKGD_01415 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HKMNKKGD_01416 1.9e-186 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HKMNKKGD_01417 1.9e-101 dhaL 2.7.1.121 S Dak2
HKMNKKGD_01418 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
HKMNKKGD_01419 2.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HKMNKKGD_01420 1e-190 malR K Transcriptional regulator, LacI family
HKMNKKGD_01421 2e-180 yvdE K helix_turn _helix lactose operon repressor
HKMNKKGD_01422 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HKMNKKGD_01423 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
HKMNKKGD_01424 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
HKMNKKGD_01425 1.4e-161 malD P ABC transporter permease
HKMNKKGD_01426 1.8e-150 malA S maltodextrose utilization protein MalA
HKMNKKGD_01427 9.1e-261 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
HKMNKKGD_01428 4e-209 msmK P Belongs to the ABC transporter superfamily
HKMNKKGD_01429 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HKMNKKGD_01430 0.0 3.2.1.96 G Glycosyl hydrolase family 85
HKMNKKGD_01431 1.5e-45 ygbF S Sugar efflux transporter for intercellular exchange
HKMNKKGD_01432 1e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HKMNKKGD_01433 0.0 rafA 3.2.1.22 G alpha-galactosidase
HKMNKKGD_01434 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HKMNKKGD_01435 3.4e-304 scrB 3.2.1.26 GH32 G invertase
HKMNKKGD_01436 9.1e-173 scrR K Transcriptional regulator, LacI family
HKMNKKGD_01437 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HKMNKKGD_01438 6.5e-165 3.5.1.10 C nadph quinone reductase
HKMNKKGD_01439 8.1e-216 nhaC C Na H antiporter NhaC
HKMNKKGD_01440 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HKMNKKGD_01441 1.8e-133 mleR K LysR substrate binding domain
HKMNKKGD_01442 0.0 3.6.4.13 M domain protein
HKMNKKGD_01444 2.1e-157 hipB K Helix-turn-helix
HKMNKKGD_01445 0.0 oppA E ABC transporter, substratebinding protein
HKMNKKGD_01446 1.3e-309 oppA E ABC transporter, substratebinding protein
HKMNKKGD_01447 2.6e-79 yiaC K Acetyltransferase (GNAT) domain
HKMNKKGD_01448 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKMNKKGD_01449 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKMNKKGD_01450 3e-113 pgm1 G phosphoglycerate mutase
HKMNKKGD_01451 1.7e-84 yghZ C Aldo keto reductase family protein
HKMNKKGD_01452 7.3e-87 yghZ C Aldo keto reductase family protein
HKMNKKGD_01453 4.9e-34
HKMNKKGD_01454 4.8e-60 S Domain of unknown function (DU1801)
HKMNKKGD_01455 6.4e-162 FbpA K Domain of unknown function (DUF814)
HKMNKKGD_01456 2.9e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKMNKKGD_01458 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKMNKKGD_01459 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKMNKKGD_01460 9.5e-262 S ATPases associated with a variety of cellular activities
HKMNKKGD_01461 0.0 L Transposase
HKMNKKGD_01462 1.8e-116 P cobalt transport
HKMNKKGD_01463 1.4e-259 P ABC transporter
HKMNKKGD_01464 3.1e-101 S ABC transporter permease
HKMNKKGD_01465 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HKMNKKGD_01466 1.4e-158 dkgB S reductase
HKMNKKGD_01467 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKMNKKGD_01468 1e-69
HKMNKKGD_01469 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKMNKKGD_01471 2.6e-277 pipD E Dipeptidase
HKMNKKGD_01472 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HKMNKKGD_01473 0.0 mtlR K Mga helix-turn-helix domain
HKMNKKGD_01474 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKMNKKGD_01475 2.8e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HKMNKKGD_01476 2.1e-73
HKMNKKGD_01477 6.2e-57 trxA1 O Belongs to the thioredoxin family
HKMNKKGD_01478 1.2e-49
HKMNKKGD_01479 1.9e-95
HKMNKKGD_01480 2e-62
HKMNKKGD_01481 3.9e-81 ndk 2.7.4.6 F Belongs to the NDK family
HKMNKKGD_01482 1.9e-253 S Uncharacterized protein conserved in bacteria (DUF2252)
HKMNKKGD_01483 3.5e-97 yieF S NADPH-dependent FMN reductase
HKMNKKGD_01484 2.7e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HKMNKKGD_01485 1.3e-210 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKMNKKGD_01486 2.2e-165 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HKMNKKGD_01487 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
HKMNKKGD_01488 4.3e-141 pnuC H nicotinamide mononucleotide transporter
HKMNKKGD_01489 7.3e-43 S Protein of unknown function (DUF2089)
HKMNKKGD_01490 2.2e-42
HKMNKKGD_01491 3.5e-129 treR K UTRA
HKMNKKGD_01492 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HKMNKKGD_01493 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HKMNKKGD_01494 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HKMNKKGD_01495 1.4e-144
HKMNKKGD_01496 4.9e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HKMNKKGD_01497 2.1e-235 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
HKMNKKGD_01498 0.0 tagF2 2.7.8.12 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKMNKKGD_01499 9.2e-168 S Psort location CytoplasmicMembrane, score
HKMNKKGD_01500 5.9e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HKMNKKGD_01501 1.6e-70
HKMNKKGD_01502 1.8e-72 K Transcriptional regulator
HKMNKKGD_01503 4.3e-121 K Bacterial regulatory proteins, tetR family
HKMNKKGD_01504 8.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
HKMNKKGD_01505 1.6e-117
HKMNKKGD_01506 5.2e-42
HKMNKKGD_01507 1e-40
HKMNKKGD_01508 9.7e-253 ydiC1 EGP Major facilitator Superfamily
HKMNKKGD_01509 3.3e-65 K helix_turn_helix, mercury resistance
HKMNKKGD_01510 1.2e-123 L PFAM transposase IS116 IS110 IS902 family
HKMNKKGD_01511 5.8e-250 T PhoQ Sensor
HKMNKKGD_01512 8.3e-128 K Transcriptional regulatory protein, C terminal
HKMNKKGD_01513 1.8e-49
HKMNKKGD_01514 2.1e-129 yidA K Helix-turn-helix domain, rpiR family
HKMNKKGD_01515 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKMNKKGD_01516 9.9e-57
HKMNKKGD_01517 2.1e-41
HKMNKKGD_01518 1.4e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HKMNKKGD_01519 2e-258 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HKMNKKGD_01520 1.3e-47
HKMNKKGD_01521 2.7e-123 2.7.6.5 S RelA SpoT domain protein
HKMNKKGD_01522 3.1e-104 K transcriptional regulator
HKMNKKGD_01523 0.0 ydgH S MMPL family
HKMNKKGD_01524 1.3e-107 tag 3.2.2.20 L glycosylase
HKMNKKGD_01525 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HKMNKKGD_01526 1.6e-192 yclI V MacB-like periplasmic core domain
HKMNKKGD_01527 7.1e-121 yclH V ABC transporter
HKMNKKGD_01528 2.5e-114 V CAAX protease self-immunity
HKMNKKGD_01529 1.6e-118 S CAAX protease self-immunity
HKMNKKGD_01530 1.7e-52 M Lysin motif
HKMNKKGD_01531 1.2e-29 lytE M LysM domain protein
HKMNKKGD_01532 7.4e-67 gcvH E Glycine cleavage H-protein
HKMNKKGD_01533 1.1e-177 sepS16B
HKMNKKGD_01534 1.3e-131
HKMNKKGD_01535 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HKMNKKGD_01536 6.8e-57
HKMNKKGD_01537 8.9e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKMNKKGD_01538 6.5e-78 elaA S GNAT family
HKMNKKGD_01539 1.7e-75 K Transcriptional regulator
HKMNKKGD_01540 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
HKMNKKGD_01541 3.1e-38
HKMNKKGD_01542 7.1e-08 S Motility quorum-sensing regulator, toxin of MqsA
HKMNKKGD_01543 1.7e-30
HKMNKKGD_01544 5.4e-21 U Preprotein translocase subunit SecB
HKMNKKGD_01545 4e-206 potD P ABC transporter
HKMNKKGD_01546 1.7e-140 potC P ABC transporter permease
HKMNKKGD_01547 2.7e-149 potB P ABC transporter permease
HKMNKKGD_01548 3.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKMNKKGD_01549 3.8e-96 puuR K Cupin domain
HKMNKKGD_01550 1.1e-83 6.3.3.2 S ASCH
HKMNKKGD_01551 1e-84 K GNAT family
HKMNKKGD_01552 8e-91 K acetyltransferase
HKMNKKGD_01553 8.1e-22
HKMNKKGD_01554 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HKMNKKGD_01555 2e-163 ytrB V ABC transporter
HKMNKKGD_01556 4.9e-190
HKMNKKGD_01557 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
HKMNKKGD_01558 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HKMNKKGD_01560 2.3e-240 xylP1 G MFS/sugar transport protein
HKMNKKGD_01561 3e-122 qmcA O prohibitin homologues
HKMNKKGD_01562 3e-30
HKMNKKGD_01563 1.7e-281 pipD E Dipeptidase
HKMNKKGD_01564 3e-40
HKMNKKGD_01565 6.8e-96 bioY S BioY family
HKMNKKGD_01566 1.4e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKMNKKGD_01567 1e-61 S CHY zinc finger
HKMNKKGD_01568 8.3e-224 mtnE 2.6.1.83 E Aminotransferase
HKMNKKGD_01569 1.1e-217
HKMNKKGD_01570 3.5e-154 tagG U Transport permease protein
HKMNKKGD_01571 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HKMNKKGD_01572 3.8e-44
HKMNKKGD_01573 3.9e-93 K Transcriptional regulator PadR-like family
HKMNKKGD_01574 2.1e-258 P Major Facilitator Superfamily
HKMNKKGD_01575 2.5e-242 amtB P ammonium transporter
HKMNKKGD_01576 5.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HKMNKKGD_01577 3.7e-44
HKMNKKGD_01578 6.3e-102 zmp1 O Zinc-dependent metalloprotease
HKMNKKGD_01579 7.2e-121 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HKMNKKGD_01580 1.5e-310 mco Q Multicopper oxidase
HKMNKKGD_01581 1.1e-54 ypaA S Protein of unknown function (DUF1304)
HKMNKKGD_01582 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
HKMNKKGD_01583 4.7e-232 flhF N Uncharacterized conserved protein (DUF2075)
HKMNKKGD_01584 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HKMNKKGD_01585 9.3e-80
HKMNKKGD_01586 1.4e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKMNKKGD_01587 1.7e-173 rihC 3.2.2.1 F Nucleoside
HKMNKKGD_01588 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKMNKKGD_01589 0.0
HKMNKKGD_01590 5.9e-79 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
HKMNKKGD_01591 6.1e-277 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKMNKKGD_01592 9.9e-180 proV E ABC transporter, ATP-binding protein
HKMNKKGD_01593 2.6e-255 gshR 1.8.1.7 C Glutathione reductase
HKMNKKGD_01594 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKMNKKGD_01595 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HKMNKKGD_01596 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HKMNKKGD_01597 0.0 M domain protein
HKMNKKGD_01598 9.7e-32 M dTDP-4-dehydrorhamnose reductase activity
HKMNKKGD_01600 9.6e-114 L Transposase and inactivated derivatives, IS30 family
HKMNKKGD_01601 1.2e-34
HKMNKKGD_01603 7.1e-29
HKMNKKGD_01604 1.4e-61
HKMNKKGD_01605 6.1e-19 S Barstar (barnase inhibitor)
HKMNKKGD_01606 9.6e-120 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HKMNKKGD_01607 2e-195 uhpT EGP Major facilitator Superfamily
HKMNKKGD_01608 6.9e-147 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
HKMNKKGD_01609 3.3e-166 K Transcriptional regulator
HKMNKKGD_01610 1.5e-149 S hydrolase
HKMNKKGD_01611 1.7e-254 brnQ U Component of the transport system for branched-chain amino acids
HKMNKKGD_01612 6.1e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKMNKKGD_01616 1.4e-52 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKMNKKGD_01617 7.2e-32
HKMNKKGD_01618 2.9e-17 plnR
HKMNKKGD_01619 5.3e-116
HKMNKKGD_01620 5.2e-23 plnK
HKMNKKGD_01621 3.5e-24 plnJ
HKMNKKGD_01622 2.5e-13
HKMNKKGD_01623 8e-113 plnP S CAAX protease self-immunity
HKMNKKGD_01625 1.7e-97 2.7.13.3 T GHKL domain
HKMNKKGD_01626 1e-131 plnD K LytTr DNA-binding domain
HKMNKKGD_01627 4.8e-129 S CAAX protease self-immunity
HKMNKKGD_01628 2.4e-22 plnF
HKMNKKGD_01629 6.7e-23
HKMNKKGD_01630 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKMNKKGD_01631 2.6e-234 mesE M Transport protein ComB
HKMNKKGD_01632 1.2e-107 S CAAX protease self-immunity
HKMNKKGD_01633 9.7e-118 ypbD S CAAX protease self-immunity
HKMNKKGD_01634 6.4e-109 V CAAX protease self-immunity
HKMNKKGD_01635 6.7e-114 S CAAX protease self-immunity
HKMNKKGD_01636 1.8e-47 higA K Helix-turn-helix XRE-family like proteins
HKMNKKGD_01637 0.0 helD 3.6.4.12 L DNA helicase
HKMNKKGD_01638 9.5e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HKMNKKGD_01639 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKMNKKGD_01640 9e-130 K UbiC transcription regulator-associated domain protein
HKMNKKGD_01641 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKMNKKGD_01642 3.9e-24
HKMNKKGD_01643 3.8e-75 S Domain of unknown function (DUF3284)
HKMNKKGD_01644 1e-30 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKMNKKGD_01645 1.2e-208 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKMNKKGD_01646 7.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKMNKKGD_01647 1e-162 GK ROK family
HKMNKKGD_01648 4.1e-133 K Helix-turn-helix domain, rpiR family
HKMNKKGD_01649 2.8e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKMNKKGD_01650 8.3e-207
HKMNKKGD_01651 3.5e-151 S Psort location Cytoplasmic, score
HKMNKKGD_01652 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HKMNKKGD_01653 6.8e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HKMNKKGD_01654 3.1e-178
HKMNKKGD_01655 1.9e-132 cobB K SIR2 family
HKMNKKGD_01656 2e-160 yunF F Protein of unknown function DUF72
HKMNKKGD_01657 2.6e-70 mutT 3.6.1.55 F DNA mismatch repair protein MutT
HKMNKKGD_01658 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKMNKKGD_01659 9.2e-212 bcr1 EGP Major facilitator Superfamily
HKMNKKGD_01660 1.5e-146 tatD L hydrolase, TatD family
HKMNKKGD_01661 5.1e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKMNKKGD_01662 8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKMNKKGD_01663 3.2e-37 veg S Biofilm formation stimulator VEG
HKMNKKGD_01664 7.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKMNKKGD_01665 5.1e-181 S Prolyl oligopeptidase family
HKMNKKGD_01666 9.8e-129 fhuC 3.6.3.35 P ABC transporter
HKMNKKGD_01667 9.2e-131 znuB U ABC 3 transport family
HKMNKKGD_01669 3.7e-43 ankB S ankyrin repeats
HKMNKKGD_01670 2.1e-31
HKMNKKGD_01671 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HKMNKKGD_01672 1.2e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKMNKKGD_01673 1.8e-150 bla1 3.5.2.6 V Beta-lactamase enzyme family
HKMNKKGD_01674 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKMNKKGD_01675 2e-183 S DUF218 domain
HKMNKKGD_01676 2.2e-126
HKMNKKGD_01677 3.7e-148 yxeH S hydrolase
HKMNKKGD_01678 9e-264 ywfO S HD domain protein
HKMNKKGD_01679 3.3e-155 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HKMNKKGD_01680 3.8e-78 ywiB S Domain of unknown function (DUF1934)
HKMNKKGD_01681 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKMNKKGD_01682 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKMNKKGD_01683 4.7e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKMNKKGD_01684 3.1e-229 tdcC E amino acid
HKMNKKGD_01685 3.7e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HKMNKKGD_01686 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HKMNKKGD_01687 6.4e-131 S YheO-like PAS domain
HKMNKKGD_01688 2.5e-26
HKMNKKGD_01689 1e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKMNKKGD_01690 3e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKMNKKGD_01691 7.8e-41 rpmE2 J Ribosomal protein L31
HKMNKKGD_01692 9.4e-214 J translation release factor activity
HKMNKKGD_01693 9.2e-127 srtA 3.4.22.70 M sortase family
HKMNKKGD_01694 1.7e-91 lemA S LemA family
HKMNKKGD_01695 1e-138 htpX O Belongs to the peptidase M48B family
HKMNKKGD_01696 2e-146
HKMNKKGD_01697 3.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKMNKKGD_01698 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKMNKKGD_01699 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKMNKKGD_01700 4.9e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKMNKKGD_01701 2.3e-63 ndoA L Toxic component of a toxin-antitoxin (TA) module
HKMNKKGD_01702 0.0 kup P Transport of potassium into the cell
HKMNKKGD_01703 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HKMNKKGD_01704 3.7e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HKMNKKGD_01705 1.2e-188 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKMNKKGD_01706 2e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKMNKKGD_01707 2.1e-129 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HKMNKKGD_01708 5.1e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine
HKMNKKGD_01709 9.4e-189 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKMNKKGD_01710 4.1e-84 S QueT transporter
HKMNKKGD_01711 4.5e-169 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HKMNKKGD_01712 2.1e-123 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
HKMNKKGD_01713 2.1e-114 S (CBS) domain
HKMNKKGD_01714 1.4e-264 S Putative peptidoglycan binding domain
HKMNKKGD_01715 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HKMNKKGD_01716 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKMNKKGD_01717 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKMNKKGD_01718 3.3e-289 yabM S Polysaccharide biosynthesis protein
HKMNKKGD_01719 2.2e-42 yabO J S4 domain protein
HKMNKKGD_01721 2.4e-63 divIC D Septum formation initiator
HKMNKKGD_01722 3.1e-74 yabR J RNA binding
HKMNKKGD_01723 2.2e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKMNKKGD_01724 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HKMNKKGD_01725 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKMNKKGD_01726 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKMNKKGD_01727 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKMNKKGD_01728 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HKMNKKGD_01731 1.5e-42 S COG NOG38524 non supervised orthologous group
HKMNKKGD_01734 3e-252 dtpT U amino acid peptide transporter
HKMNKKGD_01735 2e-151 yjjH S Calcineurin-like phosphoesterase
HKMNKKGD_01739 1.9e-27 5.3.3.19 S Cupin 2, conserved barrel domain protein
HKMNKKGD_01740 2.5e-53 S Cupin domain
HKMNKKGD_01741 4.6e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HKMNKKGD_01742 2e-192 ybiR P Citrate transporter
HKMNKKGD_01743 1.6e-151 pnuC H nicotinamide mononucleotide transporter
HKMNKKGD_01744 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKMNKKGD_01745 1e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKMNKKGD_01746 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
HKMNKKGD_01747 4.6e-137 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HKMNKKGD_01748 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKMNKKGD_01749 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKMNKKGD_01750 0.0 pacL 3.6.3.8 P P-type ATPase
HKMNKKGD_01751 8.9e-72
HKMNKKGD_01752 0.0 yhgF K Tex-like protein N-terminal domain protein
HKMNKKGD_01753 5.2e-83 ydcK S Belongs to the SprT family
HKMNKKGD_01754 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HKMNKKGD_01755 1.6e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKMNKKGD_01757 6.4e-156 G Peptidase_C39 like family
HKMNKKGD_01758 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HKMNKKGD_01759 3.4e-133 manY G PTS system
HKMNKKGD_01760 3.6e-171 manN G system, mannose fructose sorbose family IID component
HKMNKKGD_01761 4.7e-64 S Domain of unknown function (DUF956)
HKMNKKGD_01762 0.0 levR K Sigma-54 interaction domain
HKMNKKGD_01763 9.5e-71 pts10A 2.7.1.191 G PTS system fructose IIA component
HKMNKKGD_01764 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
HKMNKKGD_01765 1.3e-176 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKMNKKGD_01766 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
HKMNKKGD_01767 1.2e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
HKMNKKGD_01768 8.3e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKMNKKGD_01769 1.8e-136 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HKMNKKGD_01770 4.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HKMNKKGD_01771 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HKMNKKGD_01772 1.7e-177 EG EamA-like transporter family
HKMNKKGD_01773 2.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKMNKKGD_01774 1.8e-113 zmp2 O Zinc-dependent metalloprotease
HKMNKKGD_01775 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
HKMNKKGD_01776 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKMNKKGD_01777 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
HKMNKKGD_01778 2.1e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HKMNKKGD_01779 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKMNKKGD_01780 3.7e-205 yacL S domain protein
HKMNKKGD_01781 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKMNKKGD_01782 6.1e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKMNKKGD_01783 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKMNKKGD_01784 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKMNKKGD_01785 5.3e-98 yacP S YacP-like NYN domain
HKMNKKGD_01786 2.4e-101 sigH K Sigma-70 region 2
HKMNKKGD_01787 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HKMNKKGD_01788 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKMNKKGD_01789 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
HKMNKKGD_01790 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
HKMNKKGD_01791 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKMNKKGD_01792 1.1e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKMNKKGD_01793 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKMNKKGD_01794 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKMNKKGD_01795 9.3e-178 F DNA/RNA non-specific endonuclease
HKMNKKGD_01796 9e-39 L nuclease
HKMNKKGD_01797 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKMNKKGD_01798 2.3e-39 K Helix-turn-helix domain
HKMNKKGD_01799 2.1e-108 yvdD 3.2.2.10 S Belongs to the LOG family
HKMNKKGD_01800 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKMNKKGD_01801 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKMNKKGD_01802 6.5e-37 nrdH O Glutaredoxin
HKMNKKGD_01803 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
HKMNKKGD_01804 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKMNKKGD_01805 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKMNKKGD_01806 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKMNKKGD_01807 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKMNKKGD_01808 2.2e-38 yaaL S Protein of unknown function (DUF2508)
HKMNKKGD_01809 8.7e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKMNKKGD_01810 2.4e-53 yaaQ S Cyclic-di-AMP receptor
HKMNKKGD_01811 2.2e-185 holB 2.7.7.7 L DNA polymerase III
HKMNKKGD_01812 1e-57 yabA L Involved in initiation control of chromosome replication
HKMNKKGD_01813 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKMNKKGD_01814 2.1e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
HKMNKKGD_01815 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HKMNKKGD_01816 1.2e-210 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HKMNKKGD_01817 6.5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
HKMNKKGD_01818 7.7e-144 phnE1 3.6.1.63 U ABC transporter permease
HKMNKKGD_01819 3.8e-137 phnE 3.6.1.63 U Phosphonate ABC transporter permease
HKMNKKGD_01820 9.7e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HKMNKKGD_01821 1.9e-138 phnD P Phosphonate ABC transporter
HKMNKKGD_01822 3.7e-36 phnD P Phosphonate ABC transporter
HKMNKKGD_01823 5.6e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HKMNKKGD_01824 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HKMNKKGD_01825 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HKMNKKGD_01826 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKMNKKGD_01827 4.1e-297 uup S ABC transporter, ATP-binding protein
HKMNKKGD_01828 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKMNKKGD_01829 4.6e-109 ydiL S CAAX protease self-immunity
HKMNKKGD_01830 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKMNKKGD_01831 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKMNKKGD_01832 0.0 ydaO E amino acid
HKMNKKGD_01833 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
HKMNKKGD_01834 4.3e-145 pstS P Phosphate
HKMNKKGD_01835 1.7e-114 yvyE 3.4.13.9 S YigZ family
HKMNKKGD_01836 1.5e-258 comFA L Helicase C-terminal domain protein
HKMNKKGD_01837 4.8e-125 comFC S Competence protein
HKMNKKGD_01838 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKMNKKGD_01839 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKMNKKGD_01840 3.5e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKMNKKGD_01841 1.2e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HKMNKKGD_01842 1.5e-132 K response regulator
HKMNKKGD_01843 9.2e-251 phoR 2.7.13.3 T Histidine kinase
HKMNKKGD_01844 1.1e-150 pstS P Phosphate
HKMNKKGD_01845 6.8e-162 pstC P probably responsible for the translocation of the substrate across the membrane
HKMNKKGD_01846 1.5e-155 pstA P Phosphate transport system permease protein PstA
HKMNKKGD_01847 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKMNKKGD_01848 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKMNKKGD_01849 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
HKMNKKGD_01850 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
HKMNKKGD_01851 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HKMNKKGD_01852 1.3e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKMNKKGD_01853 2.3e-164 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKMNKKGD_01854 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HKMNKKGD_01855 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKMNKKGD_01856 1.9e-124 yliE T Putative diguanylate phosphodiesterase
HKMNKKGD_01857 6.7e-270 nox C NADH oxidase
HKMNKKGD_01858 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKMNKKGD_01859 2e-109 yviA S Protein of unknown function (DUF421)
HKMNKKGD_01860 1.1e-61 S Protein of unknown function (DUF3290)
HKMNKKGD_01861 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKMNKKGD_01862 3.3e-132 yliE T Putative diguanylate phosphodiesterase
HKMNKKGD_01863 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKMNKKGD_01864 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HKMNKKGD_01865 2.7e-211 norA EGP Major facilitator Superfamily
HKMNKKGD_01866 1.2e-117 yfbR S HD containing hydrolase-like enzyme
HKMNKKGD_01867 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKMNKKGD_01868 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKMNKKGD_01869 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKMNKKGD_01870 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKMNKKGD_01871 7.2e-264 argH 4.3.2.1 E argininosuccinate lyase
HKMNKKGD_01872 9.3e-87 S Short repeat of unknown function (DUF308)
HKMNKKGD_01873 1.1e-161 rapZ S Displays ATPase and GTPase activities
HKMNKKGD_01874 2.9e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HKMNKKGD_01875 8.3e-168 whiA K May be required for sporulation
HKMNKKGD_01876 5.8e-305 oppA E ABC transporter, substratebinding protein
HKMNKKGD_01877 1e-176 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKMNKKGD_01878 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKMNKKGD_01880 4.2e-245 rpoN K Sigma-54 factor, core binding domain
HKMNKKGD_01881 7.3e-189 cggR K Putative sugar-binding domain
HKMNKKGD_01882 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKMNKKGD_01883 3.1e-223 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HKMNKKGD_01884 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKMNKKGD_01885 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKMNKKGD_01886 1.3e-133
HKMNKKGD_01887 6.6e-295 clcA P chloride
HKMNKKGD_01888 1.2e-30 secG U Preprotein translocase
HKMNKKGD_01889 8.5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
HKMNKKGD_01890 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKMNKKGD_01891 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKMNKKGD_01892 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
HKMNKKGD_01893 1.5e-256 glnP P ABC transporter
HKMNKKGD_01894 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKMNKKGD_01895 4.6e-105 yxjI
HKMNKKGD_01896 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
HKMNKKGD_01897 1.6e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKMNKKGD_01898 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HKMNKKGD_01899 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HKMNKKGD_01900 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
HKMNKKGD_01901 1.1e-100 dnaQ 2.7.7.7 L DNA polymerase III
HKMNKKGD_01902 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
HKMNKKGD_01903 3.9e-162 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HKMNKKGD_01904 6.2e-168 murB 1.3.1.98 M Cell wall formation
HKMNKKGD_01905 0.0 yjcE P Sodium proton antiporter
HKMNKKGD_01906 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
HKMNKKGD_01907 2.5e-121 S Protein of unknown function (DUF1361)
HKMNKKGD_01908 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKMNKKGD_01909 1.6e-129 ybbR S YbbR-like protein
HKMNKKGD_01910 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKMNKKGD_01911 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKMNKKGD_01912 4.5e-123 yliE T EAL domain
HKMNKKGD_01913 6.4e-148 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HKMNKKGD_01914 3.1e-104 K Bacterial regulatory proteins, tetR family
HKMNKKGD_01915 1.6e-207 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HKMNKKGD_01916 1.5e-52
HKMNKKGD_01917 3e-72
HKMNKKGD_01918 6e-132 1.5.1.39 C nitroreductase
HKMNKKGD_01919 2.7e-138 EGP Transmembrane secretion effector
HKMNKKGD_01920 7.3e-34 G Transmembrane secretion effector
HKMNKKGD_01921 7.5e-299 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKMNKKGD_01922 1.6e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKMNKKGD_01923 1.5e-141
HKMNKKGD_01925 1.9e-71 spxA 1.20.4.1 P ArsC family
HKMNKKGD_01926 1.5e-33
HKMNKKGD_01927 1.2e-88 V VanZ like family
HKMNKKGD_01928 1.8e-241 EGP Major facilitator Superfamily
HKMNKKGD_01929 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HKMNKKGD_01930 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKMNKKGD_01931 1.8e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HKMNKKGD_01932 5e-153 licD M LicD family
HKMNKKGD_01933 1.3e-82 K Transcriptional regulator
HKMNKKGD_01934 1.5e-19
HKMNKKGD_01935 1.2e-225 pbuG S permease
HKMNKKGD_01936 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HKMNKKGD_01937 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HKMNKKGD_01938 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HKMNKKGD_01939 5.5e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HKMNKKGD_01940 2e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKMNKKGD_01941 0.0 oatA I Acyltransferase
HKMNKKGD_01942 0.0 L Transposase
HKMNKKGD_01943 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKMNKKGD_01944 5e-69 O OsmC-like protein
HKMNKKGD_01945 2.3e-47
HKMNKKGD_01946 1.5e-250 yfnA E Amino Acid
HKMNKKGD_01947 9.7e-88
HKMNKKGD_01948 9.9e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HKMNKKGD_01949 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HKMNKKGD_01950 1.8e-19
HKMNKKGD_01951 6.3e-105 gmk2 2.7.4.8 F Guanylate kinase
HKMNKKGD_01952 1.3e-81 zur P Belongs to the Fur family
HKMNKKGD_01953 7.1e-12 3.2.1.14 GH18
HKMNKKGD_01954 4.9e-148
HKMNKKGD_01956 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HKMNKKGD_01957 3e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HKMNKKGD_01958 4.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKMNKKGD_01959 1.4e-40
HKMNKKGD_01961 2.2e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKMNKKGD_01962 7.8e-149 glnH ET ABC transporter substrate-binding protein
HKMNKKGD_01963 3.5e-109 gluC P ABC transporter permease
HKMNKKGD_01964 4e-108 glnP P ABC transporter permease
HKMNKKGD_01965 1.1e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKMNKKGD_01966 2.1e-154 K CAT RNA binding domain
HKMNKKGD_01967 7.9e-258 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HKMNKKGD_01968 2.4e-141 G YdjC-like protein
HKMNKKGD_01969 2.4e-245 steT E amino acid
HKMNKKGD_01970 4.8e-73 mgrA K helix_turn_helix multiple antibiotic resistance protein
HKMNKKGD_01971 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
HKMNKKGD_01972 2e-71 K MarR family
HKMNKKGD_01973 4.9e-210 EGP Major facilitator Superfamily
HKMNKKGD_01974 3.8e-85 S membrane transporter protein
HKMNKKGD_01975 7.1e-98 K Bacterial regulatory proteins, tetR family
HKMNKKGD_01976 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKMNKKGD_01977 2.9e-78 3.6.1.55 F NUDIX domain
HKMNKKGD_01978 1.3e-48 sugE U Multidrug resistance protein
HKMNKKGD_01979 1.2e-26
HKMNKKGD_01980 5.5e-129 pgm3 G Phosphoglycerate mutase family
HKMNKKGD_01981 4.7e-125 pgm3 G Phosphoglycerate mutase family
HKMNKKGD_01982 0.0 yjbQ P TrkA C-terminal domain protein
HKMNKKGD_01983 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
HKMNKKGD_01984 2.9e-111 dedA S SNARE associated Golgi protein
HKMNKKGD_01985 0.0 helD 3.6.4.12 L DNA helicase
HKMNKKGD_01986 1.7e-165 fabK 1.3.1.9 S Nitronate monooxygenase
HKMNKKGD_01987 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HKMNKKGD_01988 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HKMNKKGD_01990 5.1e-143 spoVK O ATPase family associated with various cellular activities (AAA)
HKMNKKGD_01992 7.6e-46 L Helix-turn-helix domain
HKMNKKGD_01993 2e-18 L hmm pf00665
HKMNKKGD_01994 6.9e-29 L hmm pf00665
HKMNKKGD_01995 5.8e-22 L hmm pf00665
HKMNKKGD_01996 1.1e-78
HKMNKKGD_01997 6.2e-50
HKMNKKGD_01998 1.7e-63 K Helix-turn-helix XRE-family like proteins
HKMNKKGD_01999 6.9e-111 XK27_07075 V CAAX protease self-immunity
HKMNKKGD_02000 3.8e-57 hxlR K HxlR-like helix-turn-helix
HKMNKKGD_02001 7.1e-234 EGP Major facilitator Superfamily
HKMNKKGD_02002 4.8e-162 S Cysteine-rich secretory protein family
HKMNKKGD_02003 7.4e-38 S MORN repeat
HKMNKKGD_02004 0.0 XK27_09800 I Acyltransferase family
HKMNKKGD_02005 7.1e-37 S Transglycosylase associated protein
HKMNKKGD_02006 2.6e-84
HKMNKKGD_02007 7.2e-23
HKMNKKGD_02008 8.7e-72 asp S Asp23 family, cell envelope-related function
HKMNKKGD_02009 5.3e-72 asp2 S Asp23 family, cell envelope-related function
HKMNKKGD_02010 1.3e-145 Q Fumarylacetoacetate (FAA) hydrolase family
HKMNKKGD_02011 2.7e-156 yjdB S Domain of unknown function (DUF4767)
HKMNKKGD_02012 3.4e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HKMNKKGD_02013 1.1e-101 G Glycogen debranching enzyme
HKMNKKGD_02014 0.0 pepN 3.4.11.2 E aminopeptidase
HKMNKKGD_02015 0.0 N Uncharacterized conserved protein (DUF2075)
HKMNKKGD_02016 2.6e-44 S MazG-like family
HKMNKKGD_02017 6.1e-91 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
HKMNKKGD_02018 7.3e-55 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
HKMNKKGD_02019 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
HKMNKKGD_02021 3.5e-88 S AAA domain
HKMNKKGD_02022 2.8e-51 K sequence-specific DNA binding
HKMNKKGD_02023 1.4e-71 K sequence-specific DNA binding
HKMNKKGD_02024 2.3e-96 K Helix-turn-helix domain
HKMNKKGD_02025 9.5e-172 K Transcriptional regulator
HKMNKKGD_02026 0.0 1.3.5.4 C FMN_bind
HKMNKKGD_02028 6.7e-81 rmaD K Transcriptional regulator
HKMNKKGD_02029 2.9e-116 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKMNKKGD_02030 1.8e-253 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HKMNKKGD_02031 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
HKMNKKGD_02032 1.5e-277 pipD E Dipeptidase
HKMNKKGD_02033 5e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HKMNKKGD_02034 8.5e-41
HKMNKKGD_02035 4.1e-32 L leucine-zipper of insertion element IS481
HKMNKKGD_02036 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HKMNKKGD_02037 2.9e-162 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HKMNKKGD_02038 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
HKMNKKGD_02039 4.3e-138 S NADPH-dependent FMN reductase
HKMNKKGD_02040 3.3e-178
HKMNKKGD_02041 4.3e-220 yibE S overlaps another CDS with the same product name
HKMNKKGD_02042 1.3e-126 yibF S overlaps another CDS with the same product name
HKMNKKGD_02043 7.5e-103 3.2.2.20 K FR47-like protein
HKMNKKGD_02044 5e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HKMNKKGD_02045 5.6e-49
HKMNKKGD_02046 7.6e-191 nlhH_1 I alpha/beta hydrolase fold
HKMNKKGD_02047 1e-254 xylP2 G symporter
HKMNKKGD_02048 8e-282 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKMNKKGD_02049 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HKMNKKGD_02050 0.0 asnB 6.3.5.4 E Asparagine synthase
HKMNKKGD_02051 7.2e-50 azlD S Branched-chain amino acid transport protein (AzlD)
HKMNKKGD_02052 1.3e-120 azlC E branched-chain amino acid
HKMNKKGD_02053 4.4e-35 yyaN K MerR HTH family regulatory protein
HKMNKKGD_02054 1e-106
HKMNKKGD_02055 1.4e-117 S Domain of unknown function (DUF4811)
HKMNKKGD_02056 7e-270 lmrB EGP Major facilitator Superfamily
HKMNKKGD_02057 1.7e-84 merR K MerR HTH family regulatory protein
HKMNKKGD_02058 2.6e-58
HKMNKKGD_02059 2e-120 sirR K iron dependent repressor
HKMNKKGD_02060 6e-31 cspC K Cold shock protein
HKMNKKGD_02061 1.5e-130 thrE S Putative threonine/serine exporter
HKMNKKGD_02062 2.2e-76 S Threonine/Serine exporter, ThrE
HKMNKKGD_02063 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HKMNKKGD_02064 2.3e-119 lssY 3.6.1.27 I phosphatase
HKMNKKGD_02065 2e-154 I alpha/beta hydrolase fold
HKMNKKGD_02066 8.2e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
HKMNKKGD_02067 4.2e-92 K Transcriptional regulator
HKMNKKGD_02068 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HKMNKKGD_02069 9.7e-264 lysP E amino acid
HKMNKKGD_02070 2.5e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HKMNKKGD_02071 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HKMNKKGD_02072 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKMNKKGD_02080 6.9e-78 ctsR K Belongs to the CtsR family
HKMNKKGD_02081 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKMNKKGD_02082 1.5e-109 K Bacterial regulatory proteins, tetR family
HKMNKKGD_02083 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKMNKKGD_02084 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKMNKKGD_02085 7.8e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HKMNKKGD_02086 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKMNKKGD_02087 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKMNKKGD_02088 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKMNKKGD_02089 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HKMNKKGD_02090 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKMNKKGD_02091 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HKMNKKGD_02092 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKMNKKGD_02093 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKMNKKGD_02094 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKMNKKGD_02095 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKMNKKGD_02096 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKMNKKGD_02097 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKMNKKGD_02098 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HKMNKKGD_02099 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKMNKKGD_02100 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKMNKKGD_02101 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKMNKKGD_02102 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKMNKKGD_02103 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKMNKKGD_02104 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKMNKKGD_02105 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKMNKKGD_02106 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKMNKKGD_02107 2.2e-24 rpmD J Ribosomal protein L30
HKMNKKGD_02108 6.3e-70 rplO J Binds to the 23S rRNA
HKMNKKGD_02109 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKMNKKGD_02110 3.1e-124 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKMNKKGD_02111 3.9e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKMNKKGD_02112 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKMNKKGD_02113 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKMNKKGD_02114 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKMNKKGD_02115 2.1e-61 rplQ J Ribosomal protein L17
HKMNKKGD_02116 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKMNKKGD_02117 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
HKMNKKGD_02118 1.4e-86 ynhH S NusG domain II
HKMNKKGD_02119 0.0 ndh 1.6.99.3 C NADH dehydrogenase
HKMNKKGD_02121 1e-141 cad S FMN_bind
HKMNKKGD_02122 1.5e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKMNKKGD_02123 6.8e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKMNKKGD_02124 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKMNKKGD_02125 2.1e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKMNKKGD_02126 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKMNKKGD_02127 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKMNKKGD_02128 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HKMNKKGD_02129 2.3e-164 degV S Uncharacterised protein, DegV family COG1307
HKMNKKGD_02130 3.3e-184 ywhK S Membrane
HKMNKKGD_02131 7.6e-205 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HKMNKKGD_02132 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKMNKKGD_02133 1.3e-165 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKMNKKGD_02134 1.8e-184 aroF 2.5.1.54 E DAHP synthetase I family
HKMNKKGD_02135 1.9e-195 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKMNKKGD_02136 1.2e-242 P Sodium:sulfate symporter transmembrane region
HKMNKKGD_02137 4.1e-53 yitW S Iron-sulfur cluster assembly protein
HKMNKKGD_02138 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
HKMNKKGD_02139 4.4e-177 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
HKMNKKGD_02140 7.2e-197 K Helix-turn-helix domain
HKMNKKGD_02141 1.4e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HKMNKKGD_02142 4.5e-132 mntB 3.6.3.35 P ABC transporter
HKMNKKGD_02143 1.1e-140 mtsB U ABC 3 transport family
HKMNKKGD_02144 1.2e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
HKMNKKGD_02145 1.2e-49
HKMNKKGD_02146 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HKMNKKGD_02147 3.7e-260 citP P Sodium:sulfate symporter transmembrane region
HKMNKKGD_02148 2.9e-179 citR K sugar-binding domain protein
HKMNKKGD_02149 1.7e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HKMNKKGD_02150 5.7e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HKMNKKGD_02151 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
HKMNKKGD_02152 5.5e-164 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HKMNKKGD_02153 4.6e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HKMNKKGD_02154 7.5e-144 L PFAM Integrase, catalytic core
HKMNKKGD_02155 1.1e-48 K sequence-specific DNA binding
HKMNKKGD_02157 2.4e-16 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKMNKKGD_02158 2.6e-183 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKMNKKGD_02159 6.4e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKMNKKGD_02160 3.9e-262 frdC 1.3.5.4 C FAD binding domain
HKMNKKGD_02161 1.2e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HKMNKKGD_02162 1.4e-161 mleR K LysR family transcriptional regulator
HKMNKKGD_02163 1.8e-167 mleR K LysR family
HKMNKKGD_02164 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HKMNKKGD_02165 1.4e-165 mleP S Sodium Bile acid symporter family
HKMNKKGD_02166 5.8e-253 yfnA E Amino Acid
HKMNKKGD_02167 3e-99 S ECF transporter, substrate-specific component
HKMNKKGD_02168 2.2e-24
HKMNKKGD_02169 0.0 S Alpha beta
HKMNKKGD_02170 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
HKMNKKGD_02171 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HKMNKKGD_02172 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKMNKKGD_02173 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKMNKKGD_02174 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
HKMNKKGD_02175 2.3e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKMNKKGD_02176 2.9e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HKMNKKGD_02177 3.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
HKMNKKGD_02178 2.6e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
HKMNKKGD_02179 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKMNKKGD_02180 1e-93 S UPF0316 protein
HKMNKKGD_02181 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKMNKKGD_02182 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HKMNKKGD_02183 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKMNKKGD_02184 2.6e-198 camS S sex pheromone
HKMNKKGD_02185 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKMNKKGD_02186 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKMNKKGD_02187 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKMNKKGD_02188 1e-190 yegS 2.7.1.107 G Lipid kinase
HKMNKKGD_02189 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKMNKKGD_02190 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
HKMNKKGD_02191 0.0 yfgQ P E1-E2 ATPase
HKMNKKGD_02192 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKMNKKGD_02193 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
HKMNKKGD_02194 2.3e-151 gntR K rpiR family
HKMNKKGD_02195 9.1e-144 lys M Glycosyl hydrolases family 25
HKMNKKGD_02196 1.1e-62 S Domain of unknown function (DUF4828)
HKMNKKGD_02197 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
HKMNKKGD_02198 2.4e-189 mocA S Oxidoreductase
HKMNKKGD_02199 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
HKMNKKGD_02201 2.3e-75 T Universal stress protein family
HKMNKKGD_02202 1.4e-245 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKMNKKGD_02203 1.8e-164 S Alpha/beta hydrolase of unknown function (DUF915)
HKMNKKGD_02205 1.3e-73
HKMNKKGD_02206 5e-107
HKMNKKGD_02207 4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKMNKKGD_02208 6.9e-220 pbpX1 V Beta-lactamase
HKMNKKGD_02209 6.8e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKMNKKGD_02210 1.3e-157 yihY S Belongs to the UPF0761 family
HKMNKKGD_02211 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HKMNKKGD_02212 5.6e-203 glf 5.4.99.9 M UDP-galactopyranose mutase
HKMNKKGD_02213 2.6e-27 wcoI 2.7.10.1, 2.7.10.2 M biosynthesis protein
HKMNKKGD_02214 4.3e-21 D protein tyrosine kinase activity
HKMNKKGD_02215 8.8e-23 V Beta-lactamase
HKMNKKGD_02216 1.7e-86 cps1D M Domain of unknown function (DUF4422)
HKMNKKGD_02217 1.4e-79 cps3A S Glycosyltransferase like family 2
HKMNKKGD_02218 1.2e-45 cps M Glycosyl transferase, family 2
HKMNKKGD_02219 7.3e-77 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
HKMNKKGD_02220 7.7e-88 wzy P EpsG family
HKMNKKGD_02221 1.3e-77 1.1.1.133 S Glycosyltransferase like family 2
HKMNKKGD_02222 2.3e-177 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HKMNKKGD_02223 5.3e-164 cps3D
HKMNKKGD_02224 1.6e-111 cps3E
HKMNKKGD_02225 7.9e-163 cps3F
HKMNKKGD_02226 4.1e-206 cps3H
HKMNKKGD_02227 2.3e-201 cps3I G Acyltransferase family
HKMNKKGD_02228 1.4e-147 cps1D M Domain of unknown function (DUF4422)
HKMNKKGD_02229 6.7e-136 K helix_turn_helix, arabinose operon control protein
HKMNKKGD_02230 0.0 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HKMNKKGD_02231 9.6e-74 K helix_turn_helix multiple antibiotic resistance protein
HKMNKKGD_02232 7e-259 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HKMNKKGD_02233 4e-197 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKMNKKGD_02234 3.2e-121 rfbP M Bacterial sugar transferase
HKMNKKGD_02235 3.8e-53
HKMNKKGD_02236 7.3e-33 S Protein of unknown function (DUF2922)
HKMNKKGD_02237 7e-30
HKMNKKGD_02238 6.2e-25
HKMNKKGD_02239 1.5e-100 K DNA-templated transcription, initiation
HKMNKKGD_02240 3.9e-125
HKMNKKGD_02241 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
HKMNKKGD_02242 4.1e-106 ygaC J Belongs to the UPF0374 family
HKMNKKGD_02243 1.3e-134 cwlO M NlpC/P60 family
HKMNKKGD_02244 1e-47 K sequence-specific DNA binding
HKMNKKGD_02245 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
HKMNKKGD_02246 3.5e-149 pbpX V Beta-lactamase
HKMNKKGD_02247 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HKMNKKGD_02248 9.3e-188 yueF S AI-2E family transporter
HKMNKKGD_02249 1.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HKMNKKGD_02250 9.5e-213 gntP EG Gluconate
HKMNKKGD_02251 7.9e-293 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HKMNKKGD_02252 4.3e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HKMNKKGD_02253 8.3e-254 gor 1.8.1.7 C Glutathione reductase
HKMNKKGD_02254 2e-307 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKMNKKGD_02255 3.8e-142
HKMNKKGD_02256 1.6e-120
HKMNKKGD_02257 6.5e-198 M MucBP domain
HKMNKKGD_02258 7.1e-161 lysR5 K LysR substrate binding domain
HKMNKKGD_02259 5.5e-126 yxaA S membrane transporter protein
HKMNKKGD_02260 3.2e-57 ywjH S Protein of unknown function (DUF1634)
HKMNKKGD_02261 1.3e-309 oppA E ABC transporter, substratebinding protein
HKMNKKGD_02262 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKMNKKGD_02263 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKMNKKGD_02264 9.2e-203 oppD P Belongs to the ABC transporter superfamily
HKMNKKGD_02265 1.8e-181 oppF P Belongs to the ABC transporter superfamily
HKMNKKGD_02266 1e-63 K Winged helix DNA-binding domain
HKMNKKGD_02267 1.6e-102 L Integrase
HKMNKKGD_02268 0.0 clpE O Belongs to the ClpA ClpB family
HKMNKKGD_02269 6.5e-30
HKMNKKGD_02270 2.7e-39 ptsH G phosphocarrier protein HPR
HKMNKKGD_02271 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKMNKKGD_02272 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HKMNKKGD_02273 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
HKMNKKGD_02274 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKMNKKGD_02275 1.2e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKMNKKGD_02276 4.1e-228 patA 2.6.1.1 E Aminotransferase
HKMNKKGD_02277 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
HKMNKKGD_02278 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKMNKKGD_02281 1.5e-42 S COG NOG38524 non supervised orthologous group
HKMNKKGD_02287 5.1e-08
HKMNKKGD_02293 1.4e-90 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
HKMNKKGD_02294 1.8e-182 P secondary active sulfate transmembrane transporter activity
HKMNKKGD_02295 5.8e-94
HKMNKKGD_02296 2e-94 K Acetyltransferase (GNAT) domain
HKMNKKGD_02297 1.1e-155 T Calcineurin-like phosphoesterase superfamily domain
HKMNKKGD_02299 5.2e-232 mntH P H( )-stimulated, divalent metal cation uptake system
HKMNKKGD_02300 7.6e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HKMNKKGD_02301 1.7e-254 mmuP E amino acid
HKMNKKGD_02302 1.7e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HKMNKKGD_02303 9.3e-294 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HKMNKKGD_02304 3.1e-122
HKMNKKGD_02305 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKMNKKGD_02306 1.4e-278 bmr3 EGP Major facilitator Superfamily
HKMNKKGD_02307 4.8e-139 N Cell shape-determining protein MreB
HKMNKKGD_02308 0.0 S Pfam Methyltransferase
HKMNKKGD_02309 6.7e-268 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
HKMNKKGD_02310 1.8e-297 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HKMNKKGD_02311 4.2e-29
HKMNKKGD_02312 2.9e-93 ytqB 2.1.1.176 J Putative rRNA methylase
HKMNKKGD_02313 2e-123 3.6.1.27 I Acid phosphatase homologues
HKMNKKGD_02314 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKMNKKGD_02315 3e-301 ytgP S Polysaccharide biosynthesis protein
HKMNKKGD_02316 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKMNKKGD_02317 3.7e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKMNKKGD_02318 1.3e-273 pepV 3.5.1.18 E dipeptidase PepV
HKMNKKGD_02319 4.1e-84 uspA T Belongs to the universal stress protein A family
HKMNKKGD_02320 5.2e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
HKMNKKGD_02321 1.5e-172 ugpA U Binding-protein-dependent transport system inner membrane component
HKMNKKGD_02322 1.1e-150 ugpE G ABC transporter permease
HKMNKKGD_02323 6.4e-262 ugpB G Bacterial extracellular solute-binding protein
HKMNKKGD_02324 3.2e-95 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKMNKKGD_02325 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
HKMNKKGD_02326 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKMNKKGD_02327 3.9e-179 XK27_06930 V domain protein
HKMNKKGD_02329 1.2e-124 V Transport permease protein
HKMNKKGD_02330 2.3e-156 V ABC transporter
HKMNKKGD_02331 4e-176 K LytTr DNA-binding domain
HKMNKKGD_02332 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKMNKKGD_02333 1.6e-64 K helix_turn_helix, mercury resistance
HKMNKKGD_02334 1e-116 GM NAD(P)H-binding
HKMNKKGD_02335 1.8e-157 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKMNKKGD_02336 7.6e-149 S Sucrose-6F-phosphate phosphohydrolase
HKMNKKGD_02337 1.7e-108
HKMNKKGD_02338 2.9e-224 pltK 2.7.13.3 T GHKL domain
HKMNKKGD_02339 1.6e-137 pltR K LytTr DNA-binding domain
HKMNKKGD_02340 4.5e-55
HKMNKKGD_02341 2.5e-59
HKMNKKGD_02342 8.7e-114 S CAAX protease self-immunity
HKMNKKGD_02343 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
HKMNKKGD_02344 1e-90
HKMNKKGD_02345 2.5e-46
HKMNKKGD_02346 0.0 uvrA2 L ABC transporter
HKMNKKGD_02349 2.1e-57
HKMNKKGD_02350 3.5e-10
HKMNKKGD_02351 2.1e-180
HKMNKKGD_02352 1.9e-89 gtcA S Teichoic acid glycosylation protein
HKMNKKGD_02353 3.6e-58 S Protein of unknown function (DUF1516)
HKMNKKGD_02354 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HKMNKKGD_02355 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKMNKKGD_02356 6.1e-307 S Protein conserved in bacteria
HKMNKKGD_02357 3.3e-230 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HKMNKKGD_02358 8.7e-113 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
HKMNKKGD_02359 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
HKMNKKGD_02360 1e-304 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HKMNKKGD_02361 0.0 yfbS P Sodium:sulfate symporter transmembrane region
HKMNKKGD_02362 2.1e-244 dinF V MatE
HKMNKKGD_02363 1.9e-31
HKMNKKGD_02366 6.5e-78 elaA S Acetyltransferase (GNAT) domain
HKMNKKGD_02367 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HKMNKKGD_02368 5e-84
HKMNKKGD_02369 0.0 yhcA V MacB-like periplasmic core domain
HKMNKKGD_02370 7.6e-107
HKMNKKGD_02371 0.0 K PRD domain
HKMNKKGD_02372 5.9e-61 S Domain of unknown function (DUF3284)
HKMNKKGD_02373 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HKMNKKGD_02374 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HKMNKKGD_02375 6.1e-220 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKMNKKGD_02376 6.1e-290 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKMNKKGD_02377 4.4e-147 EGP Major facilitator Superfamily
HKMNKKGD_02378 4e-56 EGP Major facilitator Superfamily
HKMNKKGD_02379 2.7e-114 M ErfK YbiS YcfS YnhG
HKMNKKGD_02380 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKMNKKGD_02381 8.4e-284 ydfD K Alanine-glyoxylate amino-transferase
HKMNKKGD_02382 4e-102 argO S LysE type translocator
HKMNKKGD_02383 7.1e-214 arcT 2.6.1.1 E Aminotransferase
HKMNKKGD_02384 4.4e-77 argR K Regulates arginine biosynthesis genes
HKMNKKGD_02385 2.9e-12
HKMNKKGD_02386 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKMNKKGD_02387 1e-54 yheA S Belongs to the UPF0342 family
HKMNKKGD_02388 6.3e-232 yhaO L Ser Thr phosphatase family protein
HKMNKKGD_02389 0.0 L AAA domain
HKMNKKGD_02390 1.1e-186 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKMNKKGD_02391 2.1e-216
HKMNKKGD_02392 7.6e-91 3.4.21.102 M Peptidase family S41
HKMNKKGD_02393 1.1e-56 3.4.21.102 M Peptidase family S41
HKMNKKGD_02394 1.2e-177 K LysR substrate binding domain
HKMNKKGD_02395 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
HKMNKKGD_02396 0.0 1.3.5.4 C FAD binding domain
HKMNKKGD_02397 1.7e-99
HKMNKKGD_02398 3.5e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HKMNKKGD_02399 7.6e-61 M domain protein
HKMNKKGD_02400 8e-137 M domain protein
HKMNKKGD_02401 4.8e-48 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKMNKKGD_02402 7.7e-56 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKMNKKGD_02403 3.2e-52 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKMNKKGD_02404 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
HKMNKKGD_02405 1e-200 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKMNKKGD_02406 2.1e-272 mutS L ATPase domain of DNA mismatch repair MUTS family
HKMNKKGD_02407 1e-268 mutS L MutS domain V
HKMNKKGD_02408 3.4e-183 ykoT GT2 M Glycosyl transferase family 2
HKMNKKGD_02409 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKMNKKGD_02410 4.8e-67 S NUDIX domain
HKMNKKGD_02411 2.6e-149 S membrane
HKMNKKGD_02412 2.8e-238 S membrane
HKMNKKGD_02413 3.7e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKMNKKGD_02414 1.8e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HKMNKKGD_02415 6.9e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HKMNKKGD_02416 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKMNKKGD_02417 9.3e-106 GBS0088 S Nucleotidyltransferase
HKMNKKGD_02418 1.4e-106
HKMNKKGD_02419 5.1e-116 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HKMNKKGD_02420 3.3e-112 K Bacterial regulatory proteins, tetR family
HKMNKKGD_02421 4.7e-241 npr 1.11.1.1 C NADH oxidase
HKMNKKGD_02422 0.0
HKMNKKGD_02423 7.9e-61
HKMNKKGD_02424 1.4e-192 S Fn3-like domain
HKMNKKGD_02425 2e-102 S WxL domain surface cell wall-binding
HKMNKKGD_02426 3.5e-78 S WxL domain surface cell wall-binding
HKMNKKGD_02427 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKMNKKGD_02428 2e-42
HKMNKKGD_02429 9.9e-82 hit FG histidine triad
HKMNKKGD_02430 1.6e-134 ecsA V ABC transporter, ATP-binding protein
HKMNKKGD_02431 3.1e-223 ecsB U ABC transporter
HKMNKKGD_02432 9.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HKMNKKGD_02433 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKMNKKGD_02434 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
HKMNKKGD_02435 5.3e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKMNKKGD_02436 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HKMNKKGD_02437 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HKMNKKGD_02438 7.9e-21 S Virus attachment protein p12 family
HKMNKKGD_02439 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HKMNKKGD_02440 1.3e-34 feoA P FeoA domain
HKMNKKGD_02441 4.2e-144 sufC O FeS assembly ATPase SufC
HKMNKKGD_02442 2.6e-244 sufD O FeS assembly protein SufD
HKMNKKGD_02443 4.4e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKMNKKGD_02444 1.6e-82 nifU C SUF system FeS assembly protein, NifU family
HKMNKKGD_02445 1.4e-272 sufB O assembly protein SufB
HKMNKKGD_02446 5.5e-45 yitW S Iron-sulfur cluster assembly protein
HKMNKKGD_02447 2.3e-111 hipB K Helix-turn-helix
HKMNKKGD_02448 4.5e-121 ybhL S Belongs to the BI1 family
HKMNKKGD_02449 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKMNKKGD_02450 1.3e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKMNKKGD_02451 3e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKMNKKGD_02452 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKMNKKGD_02453 1.1e-248 dnaB L replication initiation and membrane attachment
HKMNKKGD_02454 3.3e-172 dnaI L Primosomal protein DnaI
HKMNKKGD_02455 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKMNKKGD_02456 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKMNKKGD_02457 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HKMNKKGD_02458 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKMNKKGD_02459 2.4e-55
HKMNKKGD_02460 7.2e-239 yrvN L AAA C-terminal domain
HKMNKKGD_02461 3.6e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKMNKKGD_02462 1e-62 hxlR K Transcriptional regulator, HxlR family
HKMNKKGD_02463 1.3e-134 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HKMNKKGD_02464 3.8e-251 pgaC GT2 M Glycosyl transferase
HKMNKKGD_02465 1.3e-79
HKMNKKGD_02466 1.4e-98 yqeG S HAD phosphatase, family IIIA
HKMNKKGD_02467 2e-216 yqeH S Ribosome biogenesis GTPase YqeH
HKMNKKGD_02468 1.1e-50 yhbY J RNA-binding protein
HKMNKKGD_02469 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKMNKKGD_02470 9.3e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HKMNKKGD_02471 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKMNKKGD_02472 4.4e-140 yqeM Q Methyltransferase
HKMNKKGD_02473 4.9e-218 ylbM S Belongs to the UPF0348 family
HKMNKKGD_02474 1.6e-97 yceD S Uncharacterized ACR, COG1399
HKMNKKGD_02475 7e-88 S Peptidase propeptide and YPEB domain
HKMNKKGD_02476 7.8e-169 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKMNKKGD_02477 3e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKMNKKGD_02478 1.9e-245 rarA L recombination factor protein RarA
HKMNKKGD_02479 4.3e-121 K response regulator
HKMNKKGD_02480 8e-307 arlS 2.7.13.3 T Histidine kinase
HKMNKKGD_02481 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HKMNKKGD_02482 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HKMNKKGD_02483 5e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKMNKKGD_02484 8.4e-94 S SdpI/YhfL protein family
HKMNKKGD_02485 1e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKMNKKGD_02486 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HKMNKKGD_02487 1e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKMNKKGD_02488 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKMNKKGD_02489 7.4e-64 yodB K Transcriptional regulator, HxlR family
HKMNKKGD_02490 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKMNKKGD_02491 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKMNKKGD_02492 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKMNKKGD_02493 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
HKMNKKGD_02494 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKMNKKGD_02495 8.6e-96 liaI S membrane
HKMNKKGD_02496 4e-75 XK27_02470 K LytTr DNA-binding domain
HKMNKKGD_02497 1.5e-54 yneR S Belongs to the HesB IscA family
HKMNKKGD_02498 0.0 S membrane
HKMNKKGD_02499 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HKMNKKGD_02500 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HKMNKKGD_02501 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKMNKKGD_02502 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
HKMNKKGD_02503 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
HKMNKKGD_02504 4.9e-179 glk 2.7.1.2 G Glucokinase
HKMNKKGD_02505 1e-108 pepE 3.4.13.21 E Belongs to the peptidase S51 family
HKMNKKGD_02506 4.4e-68 yqhL P Rhodanese-like protein
HKMNKKGD_02507 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
HKMNKKGD_02508 1.7e-139 glpQ 3.1.4.46 C phosphodiesterase
HKMNKKGD_02509 1e-173 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKMNKKGD_02510 4.6e-64 glnR K Transcriptional regulator
HKMNKKGD_02511 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
HKMNKKGD_02512 2.5e-161
HKMNKKGD_02513 4e-181
HKMNKKGD_02514 6.2e-99 dut S Protein conserved in bacteria
HKMNKKGD_02515 4.1e-56
HKMNKKGD_02516 1.7e-30
HKMNKKGD_02517 1.6e-123 L PFAM transposase IS116 IS110 IS902 family
HKMNKKGD_02520 5.4e-19
HKMNKKGD_02521 8.9e-89 K Transcriptional regulator
HKMNKKGD_02522 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HKMNKKGD_02523 3.2e-53 ysxB J Cysteine protease Prp
HKMNKKGD_02524 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HKMNKKGD_02525 1.6e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HKMNKKGD_02526 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKMNKKGD_02527 3.5e-74 yqhY S Asp23 family, cell envelope-related function
HKMNKKGD_02528 5.2e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKMNKKGD_02529 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKMNKKGD_02530 9.3e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKMNKKGD_02531 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKMNKKGD_02532 6.1e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKMNKKGD_02533 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HKMNKKGD_02534 7.4e-77 argR K Regulates arginine biosynthesis genes
HKMNKKGD_02535 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
HKMNKKGD_02536 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
HKMNKKGD_02537 1.2e-104 opuCB E ABC transporter permease
HKMNKKGD_02538 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKMNKKGD_02539 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
HKMNKKGD_02540 4.5e-55
HKMNKKGD_02541 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HKMNKKGD_02542 3.2e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKMNKKGD_02543 2.5e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKMNKKGD_02544 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKMNKKGD_02545 1.9e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKMNKKGD_02546 1.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKMNKKGD_02547 1.7e-134 stp 3.1.3.16 T phosphatase
HKMNKKGD_02548 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HKMNKKGD_02549 1.2e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKMNKKGD_02550 2.8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HKMNKKGD_02551 8.3e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
HKMNKKGD_02552 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HKMNKKGD_02553 1.8e-57 asp S Asp23 family, cell envelope-related function
HKMNKKGD_02554 0.0 yloV S DAK2 domain fusion protein YloV
HKMNKKGD_02555 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKMNKKGD_02556 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKMNKKGD_02557 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKMNKKGD_02558 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKMNKKGD_02559 0.0 smc D Required for chromosome condensation and partitioning
HKMNKKGD_02560 5.6e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKMNKKGD_02561 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKMNKKGD_02562 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKMNKKGD_02563 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HKMNKKGD_02564 2.6e-39 ylqC S Belongs to the UPF0109 family
HKMNKKGD_02565 8.2e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKMNKKGD_02566 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HKMNKKGD_02567 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKMNKKGD_02568 1.7e-51
HKMNKKGD_02569 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HKMNKKGD_02570 5.3e-86
HKMNKKGD_02571 2.3e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HKMNKKGD_02572 3.1e-271 XK27_00765
HKMNKKGD_02574 5.8e-269 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
HKMNKKGD_02575 3.3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
HKMNKKGD_02576 1.2e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKMNKKGD_02577 9.6e-125 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HKMNKKGD_02578 9.1e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HKMNKKGD_02579 2.3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKMNKKGD_02580 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKMNKKGD_02581 5.3e-98 entB 3.5.1.19 Q Isochorismatase family
HKMNKKGD_02582 2.6e-177 1.6.5.5 C Zinc-binding dehydrogenase
HKMNKKGD_02583 6e-199 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HKMNKKGD_02584 2.1e-58 S Protein of unknown function (DUF1648)
HKMNKKGD_02586 8.6e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKMNKKGD_02587 3.8e-179 yneE K Transcriptional regulator
HKMNKKGD_02588 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKMNKKGD_02589 2.9e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKMNKKGD_02590 3.8e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKMNKKGD_02591 2e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HKMNKKGD_02592 1.2e-126 IQ reductase
HKMNKKGD_02593 1.6e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKMNKKGD_02594 2.3e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKMNKKGD_02595 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HKMNKKGD_02596 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HKMNKKGD_02597 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKMNKKGD_02598 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HKMNKKGD_02599 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HKMNKKGD_02600 4.9e-99 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HKMNKKGD_02601 1.3e-123 S Protein of unknown function (DUF554)
HKMNKKGD_02602 3.6e-160 K LysR substrate binding domain
HKMNKKGD_02603 4.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
HKMNKKGD_02604 1.7e-193 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKMNKKGD_02605 2e-92 K transcriptional regulator
HKMNKKGD_02606 8.6e-304 norB EGP Major Facilitator
HKMNKKGD_02607 5.8e-139 f42a O Band 7 protein
HKMNKKGD_02608 8.5e-54
HKMNKKGD_02609 1.3e-28
HKMNKKGD_02610 2.5e-209 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HKMNKKGD_02611 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
HKMNKKGD_02612 4.2e-46 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HKMNKKGD_02613 7.9e-41
HKMNKKGD_02614 1.9e-67 tspO T TspO/MBR family
HKMNKKGD_02615 6.3e-76 uspA T Belongs to the universal stress protein A family
HKMNKKGD_02616 8e-66 S Protein of unknown function (DUF805)
HKMNKKGD_02617 4.1e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HKMNKKGD_02618 3.5e-36
HKMNKKGD_02619 3.1e-14
HKMNKKGD_02620 6.5e-41 S transglycosylase associated protein
HKMNKKGD_02621 4.8e-29 S CsbD-like
HKMNKKGD_02622 9.4e-40
HKMNKKGD_02623 8.6e-281 pipD E Dipeptidase
HKMNKKGD_02624 5.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HKMNKKGD_02625 5.7e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKMNKKGD_02626 1e-170 2.5.1.74 H UbiA prenyltransferase family
HKMNKKGD_02627 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
HKMNKKGD_02628 1.9e-49
HKMNKKGD_02629 2.4e-43
HKMNKKGD_02630 8.7e-259 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKMNKKGD_02631 1.4e-265 yfnA E Amino Acid
HKMNKKGD_02632 1.2e-149 yitU 3.1.3.104 S hydrolase
HKMNKKGD_02633 3.6e-268 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HKMNKKGD_02634 1.2e-88 S Domain of unknown function (DUF4767)
HKMNKKGD_02635 2.5e-250 malT G Major Facilitator
HKMNKKGD_02636 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HKMNKKGD_02637 1.1e-194 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HKMNKKGD_02638 4.8e-196 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKMNKKGD_02639 2.9e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HKMNKKGD_02640 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HKMNKKGD_02641 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HKMNKKGD_02642 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HKMNKKGD_02643 2.1e-72 ypmB S protein conserved in bacteria
HKMNKKGD_02644 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HKMNKKGD_02645 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HKMNKKGD_02646 1.3e-128 dnaD L Replication initiation and membrane attachment
HKMNKKGD_02648 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKMNKKGD_02649 7.7e-99 metI P ABC transporter permease
HKMNKKGD_02650 2.7e-157 metQ_4 P Belongs to the nlpA lipoprotein family
HKMNKKGD_02651 7.6e-83 uspA T Universal stress protein family
HKMNKKGD_02652 1.6e-302 ftpA P Binding-protein-dependent transport system inner membrane component
HKMNKKGD_02653 1.7e-182 ftpB P Bacterial extracellular solute-binding protein
HKMNKKGD_02654 1.8e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
HKMNKKGD_02655 1.2e-123 L PFAM transposase IS116 IS110 IS902 family
HKMNKKGD_02656 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HKMNKKGD_02657 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKMNKKGD_02658 8.3e-110 ypsA S Belongs to the UPF0398 family
HKMNKKGD_02659 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKMNKKGD_02661 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HKMNKKGD_02662 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
HKMNKKGD_02663 1.6e-123 L PFAM transposase IS116 IS110 IS902 family
HKMNKKGD_02664 3.8e-227 P Major Facilitator Superfamily
HKMNKKGD_02665 2.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HKMNKKGD_02666 1.2e-73 S SnoaL-like domain
HKMNKKGD_02667 1.8e-243 M Glycosyltransferase, group 2 family protein
HKMNKKGD_02668 5.1e-209 mccF V LD-carboxypeptidase
HKMNKKGD_02669 1.4e-78 K Acetyltransferase (GNAT) domain
HKMNKKGD_02670 4.5e-239 M hydrolase, family 25
HKMNKKGD_02671 1.4e-181 mccF 3.4.17.13 V LD-carboxypeptidase
HKMNKKGD_02672 1.2e-124
HKMNKKGD_02673 2.5e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
HKMNKKGD_02674 2.5e-192
HKMNKKGD_02675 3.4e-146 S hydrolase activity, acting on ester bonds
HKMNKKGD_02676 3.2e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
HKMNKKGD_02677 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
HKMNKKGD_02678 3.3e-62 esbA S Family of unknown function (DUF5322)
HKMNKKGD_02679 4.6e-294 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HKMNKKGD_02680 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKMNKKGD_02681 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKMNKKGD_02682 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKMNKKGD_02683 4.7e-207 carA 6.3.5.5 F Belongs to the CarA family
HKMNKKGD_02684 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HKMNKKGD_02685 6.4e-113 pgm5 G Phosphoglycerate mutase family
HKMNKKGD_02686 5.8e-70 frataxin S Domain of unknown function (DU1801)
HKMNKKGD_02688 1.1e-129 cat 2.3.1.28 V Chloramphenicol acetyltransferase
HKMNKKGD_02689 3.5e-69 S LuxR family transcriptional regulator
HKMNKKGD_02690 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
HKMNKKGD_02692 1.2e-91 3.6.1.55 F NUDIX domain
HKMNKKGD_02693 1.7e-162 V ABC transporter, ATP-binding protein
HKMNKKGD_02694 1.3e-131 S ABC-2 family transporter protein
HKMNKKGD_02695 0.0 FbpA K Fibronectin-binding protein
HKMNKKGD_02696 1.9e-66 K Transcriptional regulator
HKMNKKGD_02697 7e-161 degV S EDD domain protein, DegV family
HKMNKKGD_02698 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HKMNKKGD_02699 3.4e-132 S Protein of unknown function (DUF975)
HKMNKKGD_02700 1.3e-09
HKMNKKGD_02701 1.4e-49
HKMNKKGD_02702 6.6e-150 2.7.7.12 C Domain of unknown function (DUF4931)
HKMNKKGD_02703 4.6e-211 pmrB EGP Major facilitator Superfamily
HKMNKKGD_02704 4.6e-12
HKMNKKGD_02705 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HKMNKKGD_02706 4.6e-129 yejC S Protein of unknown function (DUF1003)
HKMNKKGD_02707 2.5e-134 XK27_00890 S Domain of unknown function (DUF368)
HKMNKKGD_02708 2.1e-244 cycA E Amino acid permease
HKMNKKGD_02709 6.5e-114
HKMNKKGD_02710 4.1e-59
HKMNKKGD_02711 1.1e-279 lldP C L-lactate permease
HKMNKKGD_02712 3.9e-227
HKMNKKGD_02713 3.3e-118 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HKMNKKGD_02714 9.7e-194 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HKMNKKGD_02715 6.8e-217 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKMNKKGD_02716 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKMNKKGD_02717 5.3e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HKMNKKGD_02718 7.8e-76 mgrA K helix_turn_helix multiple antibiotic resistance protein
HKMNKKGD_02719 4.6e-252 gshR1 1.8.1.7 C Glutathione reductase
HKMNKKGD_02720 2.5e-65
HKMNKKGD_02721 2.4e-69 M Glycosyl transferase family group 2
HKMNKKGD_02722 1.4e-161 M Glycosyl transferase family group 2
HKMNKKGD_02723 1.2e-277 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKMNKKGD_02724 2.9e-53 tnp2PF3 L Transposase
HKMNKKGD_02725 1.1e-33 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HKMNKKGD_02726 1.8e-156 xerD L Phage integrase, N-terminal SAM-like domain
HKMNKKGD_02727 4.2e-32 S YozE SAM-like fold
HKMNKKGD_02728 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKMNKKGD_02729 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HKMNKKGD_02730 1.7e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
HKMNKKGD_02731 1.2e-177 K Transcriptional regulator
HKMNKKGD_02732 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKMNKKGD_02733 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKMNKKGD_02734 6.7e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKMNKKGD_02735 2.2e-170 lacX 5.1.3.3 G Aldose 1-epimerase
HKMNKKGD_02736 2.3e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKMNKKGD_02737 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKMNKKGD_02738 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HKMNKKGD_02739 7.3e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKMNKKGD_02740 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKMNKKGD_02741 3.3e-158 dprA LU DNA protecting protein DprA
HKMNKKGD_02742 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKMNKKGD_02743 1.8e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKMNKKGD_02745 1.4e-228 XK27_05470 E Methionine synthase
HKMNKKGD_02746 2.3e-170 cpsY K Transcriptional regulator, LysR family
HKMNKKGD_02747 3.3e-172 L restriction endonuclease
HKMNKKGD_02748 2.5e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HKMNKKGD_02749 7.4e-197 XK27_00915 C Luciferase-like monooxygenase
HKMNKKGD_02750 3.3e-251 emrY EGP Major facilitator Superfamily
HKMNKKGD_02751 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HKMNKKGD_02752 3.4e-35 yozE S Belongs to the UPF0346 family
HKMNKKGD_02753 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HKMNKKGD_02754 8.8e-149 ypmR E GDSL-like Lipase/Acylhydrolase
HKMNKKGD_02755 5.1e-148 DegV S EDD domain protein, DegV family
HKMNKKGD_02756 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKMNKKGD_02757 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKMNKKGD_02758 0.0 yfmR S ABC transporter, ATP-binding protein
HKMNKKGD_02759 9.6e-85
HKMNKKGD_02760 2.5e-228 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKMNKKGD_02761 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKMNKKGD_02762 3.3e-149 3.1.3.102, 3.1.3.104 S hydrolase
HKMNKKGD_02763 1.6e-214 S Tetratricopeptide repeat protein
HKMNKKGD_02764 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKMNKKGD_02765 2.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HKMNKKGD_02766 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
HKMNKKGD_02767 1.1e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HKMNKKGD_02768 2e-19 M Lysin motif
HKMNKKGD_02769 1.2e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HKMNKKGD_02770 1.1e-195 ypbB 5.1.3.1 S Helix-turn-helix domain
HKMNKKGD_02771 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKMNKKGD_02772 1.2e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKMNKKGD_02773 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKMNKKGD_02774 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKMNKKGD_02775 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKMNKKGD_02776 1.1e-164 xerD D recombinase XerD
HKMNKKGD_02777 2.9e-170 cvfB S S1 domain
HKMNKKGD_02778 1.5e-74 yeaL S Protein of unknown function (DUF441)
HKMNKKGD_02779 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HKMNKKGD_02780 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKMNKKGD_02781 0.0 dnaE 2.7.7.7 L DNA polymerase
HKMNKKGD_02782 7.3e-29 S Protein of unknown function (DUF2929)
HKMNKKGD_02783 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKMNKKGD_02784 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HKMNKKGD_02785 1.1e-197 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKMNKKGD_02786 1.6e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
HKMNKKGD_02787 9e-223 M O-Antigen ligase
HKMNKKGD_02788 5.4e-120 drrB U ABC-2 type transporter
HKMNKKGD_02789 7.1e-167 drrA V ABC transporter
HKMNKKGD_02790 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
HKMNKKGD_02791 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HKMNKKGD_02792 1.6e-61 P Rhodanese Homology Domain
HKMNKKGD_02793 2.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
HKMNKKGD_02794 1.7e-207
HKMNKKGD_02795 9.7e-79 I transferase activity, transferring acyl groups other than amino-acyl groups
HKMNKKGD_02796 1.1e-123 I transferase activity, transferring acyl groups other than amino-acyl groups
HKMNKKGD_02797 1.1e-181 C Zinc-binding dehydrogenase
HKMNKKGD_02798 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
HKMNKKGD_02799 6.8e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKMNKKGD_02800 7.6e-242 EGP Major facilitator Superfamily
HKMNKKGD_02801 4.3e-77 K Transcriptional regulator
HKMNKKGD_02802 2.6e-211 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HKMNKKGD_02803 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKMNKKGD_02804 8e-137 K DeoR C terminal sensor domain
HKMNKKGD_02805 1.7e-108 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
HKMNKKGD_02806 3.5e-70 yneH 1.20.4.1 P ArsC family
HKMNKKGD_02807 1.4e-68 S Protein of unknown function (DUF1722)
HKMNKKGD_02808 1.2e-112 GM epimerase
HKMNKKGD_02809 0.0 CP_1020 S Zinc finger, swim domain protein
HKMNKKGD_02810 1.4e-119 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
HKMNKKGD_02811 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HKMNKKGD_02812 1.3e-128 K Helix-turn-helix domain, rpiR family
HKMNKKGD_02813 1.4e-158 S Alpha beta hydrolase
HKMNKKGD_02814 9e-113 GM NmrA-like family
HKMNKKGD_02815 4.1e-77 S Uncharacterized protein conserved in bacteria (DUF2255)
HKMNKKGD_02816 9.4e-161 K Transcriptional regulator
HKMNKKGD_02817 1.6e-171 C nadph quinone reductase
HKMNKKGD_02818 4.8e-14 S Alpha beta hydrolase
HKMNKKGD_02819 3e-270 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKMNKKGD_02820 1.2e-103 desR K helix_turn_helix, Lux Regulon
HKMNKKGD_02821 5.5e-203 desK 2.7.13.3 T Histidine kinase
HKMNKKGD_02822 3.8e-134 yvfS V ABC-2 type transporter
HKMNKKGD_02823 2.2e-157 yvfR V ABC transporter
HKMNKKGD_02825 6e-82 K Acetyltransferase (GNAT) domain
HKMNKKGD_02826 2.1e-73 K MarR family
HKMNKKGD_02827 3.8e-114 S Psort location CytoplasmicMembrane, score
HKMNKKGD_02828 3.9e-162 V ABC transporter, ATP-binding protein
HKMNKKGD_02829 9.8e-127 S ABC-2 family transporter protein
HKMNKKGD_02830 3.6e-199
HKMNKKGD_02831 3.5e-202
HKMNKKGD_02832 4.8e-165 ytrB V ABC transporter, ATP-binding protein
HKMNKKGD_02833 9.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
HKMNKKGD_02834 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKMNKKGD_02835 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKMNKKGD_02836 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HKMNKKGD_02837 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HKMNKKGD_02838 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
HKMNKKGD_02839 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKMNKKGD_02840 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HKMNKKGD_02841 6.6e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKMNKKGD_02842 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
HKMNKKGD_02843 4e-197 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKMNKKGD_02844 2.6e-71 yqeY S YqeY-like protein
HKMNKKGD_02845 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HKMNKKGD_02846 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKMNKKGD_02847 1.7e-128 C Enoyl-(Acyl carrier protein) reductase
HKMNKKGD_02848 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKMNKKGD_02849 2.9e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKMNKKGD_02850 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKMNKKGD_02851 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKMNKKGD_02852 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKMNKKGD_02853 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
HKMNKKGD_02854 1.9e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HKMNKKGD_02855 7.8e-165 yniA G Fructosamine kinase
HKMNKKGD_02856 7.9e-114 3.1.3.18 J HAD-hyrolase-like
HKMNKKGD_02857 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKMNKKGD_02858 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKMNKKGD_02859 9.6e-58
HKMNKKGD_02860 2.9e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKMNKKGD_02861 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
HKMNKKGD_02862 3.6e-114 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HKMNKKGD_02863 1.4e-49
HKMNKKGD_02864 1.4e-49
HKMNKKGD_02867 4e-127 3.6.4.12 L Belongs to the 'phage' integrase family
HKMNKKGD_02868 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKMNKKGD_02869 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKMNKKGD_02870 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKMNKKGD_02871 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HKMNKKGD_02872 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKMNKKGD_02873 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
HKMNKKGD_02874 4.4e-198 pbpX2 V Beta-lactamase
HKMNKKGD_02875 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKMNKKGD_02876 0.0 dnaK O Heat shock 70 kDa protein
HKMNKKGD_02877 5.6e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKMNKKGD_02878 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKMNKKGD_02879 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HKMNKKGD_02880 1.2e-188 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HKMNKKGD_02881 9.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKMNKKGD_02882 3.1e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKMNKKGD_02883 1.3e-196 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HKMNKKGD_02884 2e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKMNKKGD_02885 8.5e-93
HKMNKKGD_02886 6e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKMNKKGD_02887 2.5e-264 ydiN 5.4.99.5 G Major Facilitator
HKMNKKGD_02888 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKMNKKGD_02889 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKMNKKGD_02890 1.6e-46 ylxQ J ribosomal protein
HKMNKKGD_02891 2.8e-48 ylxR K Protein of unknown function (DUF448)
HKMNKKGD_02892 1.1e-217 nusA K Participates in both transcription termination and antitermination
HKMNKKGD_02893 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
HKMNKKGD_02894 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKMNKKGD_02895 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKMNKKGD_02896 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HKMNKKGD_02897 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
HKMNKKGD_02898 8.9e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKMNKKGD_02899 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKMNKKGD_02900 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HKMNKKGD_02901 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKMNKKGD_02902 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
HKMNKKGD_02903 4.7e-134 S Haloacid dehalogenase-like hydrolase
HKMNKKGD_02904 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKMNKKGD_02905 2e-49 yazA L GIY-YIG catalytic domain protein
HKMNKKGD_02906 2.8e-137 yabB 2.1.1.223 L Methyltransferase small domain
HKMNKKGD_02907 6.4e-119 plsC 2.3.1.51 I Acyltransferase
HKMNKKGD_02908 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
HKMNKKGD_02909 2.9e-36 ynzC S UPF0291 protein
HKMNKKGD_02910 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKMNKKGD_02911 5.4e-86
HKMNKKGD_02912 2.3e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HKMNKKGD_02913 9.2e-76
HKMNKKGD_02914 1.3e-66
HKMNKKGD_02915 9.9e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
HKMNKKGD_02918 2.1e-08 S Short C-terminal domain
HKMNKKGD_02919 1.9e-25 S Short C-terminal domain
HKMNKKGD_02921 2.9e-43 L HTH-like domain
HKMNKKGD_02922 7.5e-36 L transposase activity
HKMNKKGD_02923 6.5e-61 S Phage integrase family
HKMNKKGD_02926 1.6e-31
HKMNKKGD_02927 1.5e-143 Q Methyltransferase
HKMNKKGD_02928 8.5e-57 ybjQ S Belongs to the UPF0145 family
HKMNKKGD_02929 7.2e-212 EGP Major facilitator Superfamily
HKMNKKGD_02930 1e-102 K Helix-turn-helix domain
HKMNKKGD_02931 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKMNKKGD_02932 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HKMNKKGD_02933 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
HKMNKKGD_02934 2.8e-140 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKMNKKGD_02935 2.8e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKMNKKGD_02936 3.2e-46
HKMNKKGD_02937 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKMNKKGD_02938 1.5e-135 fruR K DeoR C terminal sensor domain
HKMNKKGD_02939 1.8e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKMNKKGD_02940 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HKMNKKGD_02941 1.8e-253 cpdA S Calcineurin-like phosphoesterase
HKMNKKGD_02942 5.7e-264 cps4J S Polysaccharide biosynthesis protein
HKMNKKGD_02943 2.7e-177 cps4I M Glycosyltransferase like family 2
HKMNKKGD_02944 1.6e-233
HKMNKKGD_02945 2.9e-190 cps4G M Glycosyltransferase Family 4
HKMNKKGD_02946 1.2e-202 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
HKMNKKGD_02947 7.9e-128 tuaA M Bacterial sugar transferase
HKMNKKGD_02948 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
HKMNKKGD_02949 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
HKMNKKGD_02950 7.3e-124 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HKMNKKGD_02951 6.4e-126 epsB M biosynthesis protein
HKMNKKGD_02952 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKMNKKGD_02953 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKMNKKGD_02954 9.2e-270 glnPH2 P ABC transporter permease
HKMNKKGD_02955 4.3e-22
HKMNKKGD_02956 9.9e-73 S Iron-sulphur cluster biosynthesis
HKMNKKGD_02957 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HKMNKKGD_02958 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HKMNKKGD_02959 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKMNKKGD_02960 4.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKMNKKGD_02961 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKMNKKGD_02962 4.1e-159 S Tetratricopeptide repeat
HKMNKKGD_02963 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKMNKKGD_02964 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKMNKKGD_02965 1.3e-192 mdtG EGP Major Facilitator Superfamily
HKMNKKGD_02966 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKMNKKGD_02967 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HKMNKKGD_02968 3.1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
HKMNKKGD_02969 0.0 comEC S Competence protein ComEC
HKMNKKGD_02970 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
HKMNKKGD_02971 7.6e-80 comEA L Competence protein ComEA
HKMNKKGD_02972 9.6e-197 ylbL T Belongs to the peptidase S16 family
HKMNKKGD_02973 1.4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKMNKKGD_02974 1.1e-101 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HKMNKKGD_02975 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HKMNKKGD_02976 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HKMNKKGD_02977 1.6e-205 ftsW D Belongs to the SEDS family
HKMNKKGD_02978 1.9e-273
HKMNKKGD_02979 5.1e-259 ica2 GT2 M Glycosyl transferase family group 2
HKMNKKGD_02980 1.6e-182
HKMNKKGD_02981 0.0 typA T GTP-binding protein TypA
HKMNKKGD_02982 2.4e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HKMNKKGD_02983 3.3e-46 yktA S Belongs to the UPF0223 family
HKMNKKGD_02984 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
HKMNKKGD_02985 4.5e-266 lpdA 1.8.1.4 C Dehydrogenase
HKMNKKGD_02986 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKMNKKGD_02987 5.8e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HKMNKKGD_02988 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HKMNKKGD_02989 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKMNKKGD_02990 1.6e-85
HKMNKKGD_02991 3.1e-33 ykzG S Belongs to the UPF0356 family
HKMNKKGD_02992 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKMNKKGD_02993 2.2e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HKMNKKGD_02994 1.7e-28
HKMNKKGD_02995 5.5e-105 mltD CBM50 M NlpC P60 family protein
HKMNKKGD_02996 0.0 L Transposase
HKMNKKGD_02997 2.2e-171 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKMNKKGD_02998 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKMNKKGD_02999 1.6e-120 S Repeat protein
HKMNKKGD_03000 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HKMNKKGD_03001 4e-197 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKMNKKGD_03002 5.5e-267 N domain, Protein
HKMNKKGD_03003 1.7e-193 S Bacterial protein of unknown function (DUF916)
HKMNKKGD_03004 2.3e-120 N WxL domain surface cell wall-binding
HKMNKKGD_03005 2.6e-115 ktrA P domain protein
HKMNKKGD_03006 1.3e-241 ktrB P Potassium uptake protein
HKMNKKGD_03007 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKMNKKGD_03008 4.9e-57 XK27_04120 S Putative amino acid metabolism
HKMNKKGD_03009 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
HKMNKKGD_03010 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKMNKKGD_03011 4.6e-28
HKMNKKGD_03012 5.6e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HKMNKKGD_03013 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKMNKKGD_03014 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKMNKKGD_03015 1.2e-86 divIVA D DivIVA domain protein
HKMNKKGD_03016 3.4e-146 ylmH S S4 domain protein
HKMNKKGD_03017 1.2e-36 yggT S YGGT family
HKMNKKGD_03018 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKMNKKGD_03019 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKMNKKGD_03020 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKMNKKGD_03021 1.5e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKMNKKGD_03022 1.5e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKMNKKGD_03023 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKMNKKGD_03024 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKMNKKGD_03025 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HKMNKKGD_03026 7.5e-54 ftsL D Cell division protein FtsL
HKMNKKGD_03027 1e-98 K Primase C terminal 1 (PriCT-1)
HKMNKKGD_03029 8.8e-27
HKMNKKGD_03030 5.6e-68 S protein conserved in bacteria
HKMNKKGD_03031 3e-10
HKMNKKGD_03032 2.5e-27
HKMNKKGD_03033 0.0 L MobA MobL family protein
HKMNKKGD_03034 2.6e-14
HKMNKKGD_03035 5.1e-81
HKMNKKGD_03036 5.7e-50 S Cag pathogenicity island, type IV secretory system
HKMNKKGD_03037 7.8e-37
HKMNKKGD_03038 1.4e-116
HKMNKKGD_03039 0.0 U AAA-like domain
HKMNKKGD_03040 1.5e-232 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
HKMNKKGD_03041 6.6e-162 M CHAP domain
HKMNKKGD_03042 7e-54
HKMNKKGD_03043 5.7e-43 CO COG0526, thiol-disulfide isomerase and thioredoxins
HKMNKKGD_03044 5.3e-67
HKMNKKGD_03045 1e-223 traK U TraM recognition site of TraD and TraG
HKMNKKGD_03047 1.6e-75
HKMNKKGD_03048 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKMNKKGD_03049 6.2e-34
HKMNKKGD_03050 1e-196 L Psort location Cytoplasmic, score
HKMNKKGD_03051 5.9e-145 L COG3547 Transposase and inactivated derivatives
HKMNKKGD_03052 1.2e-72 V ABC transporter
HKMNKKGD_03053 2.4e-170
HKMNKKGD_03055 2.7e-56
HKMNKKGD_03056 4.6e-49
HKMNKKGD_03057 1.1e-250 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HKMNKKGD_03059 2.6e-75 S Protein of unknown function with HXXEE motif
HKMNKKGD_03060 1e-11 K Bacterial regulatory proteins, tetR family
HKMNKKGD_03064 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKMNKKGD_03065 1.5e-234 mesE M Transport protein ComB
HKMNKKGD_03066 2.7e-70 3.1.21.3 V Type I restriction modification DNA specificity domain
HKMNKKGD_03067 2.5e-95 tnpR1 L Resolvase, N terminal domain
HKMNKKGD_03068 8.5e-300 K Sigma-54 interaction domain
HKMNKKGD_03069 9.6e-42 levA G PTS system fructose IIA component
HKMNKKGD_03070 6.6e-79 2.7.1.191 G PTS system sorbose subfamily IIB component
HKMNKKGD_03071 1.4e-137 M PTS system sorbose-specific iic component
HKMNKKGD_03072 1.4e-134 levD G PTS system mannose/fructose/sorbose family IID component
HKMNKKGD_03073 1.7e-38
HKMNKKGD_03074 7.8e-242 G Glycosyl hydrolases family 32
HKMNKKGD_03075 4.8e-75 M1-798 K Rhodanese Homology Domain
HKMNKKGD_03076 1e-20 CO cell redox homeostasis
HKMNKKGD_03077 4.4e-137 trxB 1.8.1.9 O Glucose inhibited division protein A
HKMNKKGD_03078 5.7e-99 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HKMNKKGD_03080 5.1e-45 trxA O Belongs to the thioredoxin family
HKMNKKGD_03081 6.1e-164 gor 1.8.1.7 C Pyridine nucleotide-disulphide oxidoreductase
HKMNKKGD_03083 1.1e-66 slyA K helix_turn_helix multiple antibiotic resistance protein
HKMNKKGD_03084 8.2e-41 osmC O OsmC-like protein
HKMNKKGD_03085 2.9e-35 osmC O OsmC-like protein
HKMNKKGD_03086 5.2e-195 tra L Transposase and inactivated derivatives, IS30 family
HKMNKKGD_03087 6.1e-27 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HKMNKKGD_03088 1.7e-19
HKMNKKGD_03090 4e-135 D Cellulose biosynthesis protein BcsQ
HKMNKKGD_03091 9e-155 S Protein of unknown function (DUF917)
HKMNKKGD_03092 6e-203 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
HKMNKKGD_03093 1.8e-14 L Transposase
HKMNKKGD_03094 5.7e-197 L Transposase
HKMNKKGD_03095 2.4e-101
HKMNKKGD_03096 1.8e-270 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKMNKKGD_03097 1.1e-84 S Membrane
HKMNKKGD_03098 8.8e-156 L Transposase and inactivated derivatives, IS30 family
HKMNKKGD_03099 4.7e-81 nrdI F NrdI Flavodoxin like
HKMNKKGD_03100 4.5e-110 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKMNKKGD_03101 7.3e-283 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKMNKKGD_03102 1.7e-168 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
HKMNKKGD_03103 5.5e-183 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
HKMNKKGD_03104 8.6e-47 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HKMNKKGD_03105 1.2e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
HKMNKKGD_03106 7e-155 tesE Q hydratase
HKMNKKGD_03107 1.4e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HKMNKKGD_03108 2.3e-96 tnpR1 L Resolvase, N terminal domain
HKMNKKGD_03109 7.9e-60 K helix_turn_helix multiple antibiotic resistance protein
HKMNKKGD_03110 0.0 kup P Transport of potassium into the cell
HKMNKKGD_03111 1.1e-36 lytE M LysM domain protein
HKMNKKGD_03113 1.2e-174 L Transposase and inactivated derivatives, IS30 family
HKMNKKGD_03114 3.6e-82 L Integrase core domain
HKMNKKGD_03115 2.7e-36 L Transposase and inactivated derivatives
HKMNKKGD_03116 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HKMNKKGD_03117 3.6e-106 L Resolvase, N terminal domain
HKMNKKGD_03118 1.2e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKMNKKGD_03119 3.5e-76 L Transposase DDE domain
HKMNKKGD_03120 1.8e-68 L Putative transposase of IS4/5 family (DUF4096)
HKMNKKGD_03123 2.7e-143 D CobQ CobB MinD ParA nucleotide binding domain protein
HKMNKKGD_03125 4.7e-51 repA S Replication initiator protein A
HKMNKKGD_03126 3.9e-44 relB L Addiction module antitoxin, RelB DinJ family
HKMNKKGD_03127 1.9e-77
HKMNKKGD_03128 1.5e-40
HKMNKKGD_03129 2.5e-27
HKMNKKGD_03130 0.0 traA L MobA MobL family protein
HKMNKKGD_03131 4.3e-36
HKMNKKGD_03132 6.7e-28
HKMNKKGD_03133 2e-33 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HKMNKKGD_03134 0.0 treB G phosphotransferase system
HKMNKKGD_03135 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HKMNKKGD_03136 1e-125 treR K UTRA
HKMNKKGD_03137 2e-98 tnpR L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HKMNKKGD_03138 3.3e-172 L Transposase and inactivated derivatives, IS30 family
HKMNKKGD_03139 5.1e-130 EGP Major facilitator Superfamily
HKMNKKGD_03140 5.7e-186 yxaB GM Polysaccharide pyruvyl transferase
HKMNKKGD_03141 1.3e-242 iolT EGP Major facilitator Superfamily
HKMNKKGD_03142 5.9e-12
HKMNKKGD_03144 2.9e-117 KT Purine catabolism regulatory protein-like family
HKMNKKGD_03145 4.1e-165 F Permease for cytosine/purines, uracil, thiamine, allantoin
HKMNKKGD_03146 0.0 L MobA MobL family protein
HKMNKKGD_03147 3.9e-290 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKMNKKGD_03148 2e-32
HKMNKKGD_03149 5.1e-180 L Psort location Cytoplasmic, score
HKMNKKGD_03150 6.9e-85 3.1.21.3 V Type I restriction modification DNA specificity domain
HKMNKKGD_03151 1.4e-303 hsdM 2.1.1.72 V type I restriction-modification system
HKMNKKGD_03152 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HKMNKKGD_03153 4e-56
HKMNKKGD_03154 6.7e-148 levD G PTS system mannose/fructose/sorbose family IID component
HKMNKKGD_03155 1.2e-136 M PTS system sorbose-specific iic component
HKMNKKGD_03156 1.4e-89 2.7.1.191 G PTS system sorbose subfamily IIB component
HKMNKKGD_03157 1.8e-72 levA G PTS system fructose IIA component
HKMNKKGD_03158 0.0 K Sigma-54 interaction domain
HKMNKKGD_03159 1e-17 S FRG
HKMNKKGD_03161 5.8e-146 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
HKMNKKGD_03162 6.2e-57 K helix_turn_helix multiple antibiotic resistance protein
HKMNKKGD_03163 4e-243 dinF V MatE
HKMNKKGD_03167 5.6e-144 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKMNKKGD_03168 2.5e-32 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HKMNKKGD_03169 1.5e-178 arsB U Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HKMNKKGD_03170 7.9e-60 mleR K LysR substrate binding domain
HKMNKKGD_03171 5.4e-132 K LysR family
HKMNKKGD_03172 2.4e-301 1.3.5.4 C FMN_bind
HKMNKKGD_03173 2.8e-239 P Sodium:sulfate symporter transmembrane region
HKMNKKGD_03174 1.2e-82 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HKMNKKGD_03175 9.2e-78 L Transposase
HKMNKKGD_03176 3.2e-130 L Transposase
HKMNKKGD_03177 1.4e-175 L Integrase core domain
HKMNKKGD_03178 1.1e-30 KT PspC domain protein
HKMNKKGD_03179 3e-80 ydhK M Protein of unknown function (DUF1541)
HKMNKKGD_03180 1.4e-189 L PFAM Integrase, catalytic core
HKMNKKGD_03181 3.7e-221 S Calcineurin-like phosphoesterase
HKMNKKGD_03182 5.8e-55 asnB 6.3.5.4 E Asparagine synthase
HKMNKKGD_03183 1.5e-39 KLT serine threonine protein kinase
HKMNKKGD_03184 4.4e-33
HKMNKKGD_03185 3.8e-35
HKMNKKGD_03186 9.3e-234 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HKMNKKGD_03187 6.4e-26
HKMNKKGD_03188 1.4e-95 D Cellulose biosynthesis protein BcsQ
HKMNKKGD_03189 2.3e-98 K Primase C terminal 1 (PriCT-1)
HKMNKKGD_03190 4.6e-08 I mechanosensitive ion channel activity
HKMNKKGD_03191 2.3e-78 repA S Replication initiator protein A
HKMNKKGD_03192 1.8e-27
HKMNKKGD_03193 9.8e-34 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HKMNKKGD_03194 4.5e-67 tnp2PF3 L Transposase
HKMNKKGD_03195 1.5e-32 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HKMNKKGD_03196 3.2e-33 S protein conserved in bacteria
HKMNKKGD_03197 1.6e-42
HKMNKKGD_03198 2.1e-66 L Putative transposase of IS4/5 family (DUF4096)
HKMNKKGD_03199 5e-35 L 4.5 Transposon and IS
HKMNKKGD_03200 4.9e-73 L 4.5 Transposon and IS
HKMNKKGD_03201 3e-130 tnp L DDE domain
HKMNKKGD_03202 1.6e-23 tnpR L Resolvase, N terminal domain
HKMNKKGD_03203 9.8e-34 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HKMNKKGD_03204 3.4e-67 tnp2PF3 L Transposase
HKMNKKGD_03205 3.4e-132 L PFAM Integrase, catalytic core
HKMNKKGD_03206 1.8e-28 fhuC 3.6.3.34 HP ATPases associated with a variety of cellular activities
HKMNKKGD_03207 2e-49 U FecCD transport family
HKMNKKGD_03208 1.4e-55 isdE P Periplasmic binding protein
HKMNKKGD_03209 3.7e-26 M Iron Transport-associated domain
HKMNKKGD_03211 2.4e-175 L Transposase and inactivated derivatives, IS30 family
HKMNKKGD_03212 5.8e-10 S Enterocin A Immunity
HKMNKKGD_03213 0.0 dld 1.1.5.12 C D-lactate dehydrogenase, membrane binding
HKMNKKGD_03214 6.6e-156 L Integrase core domain
HKMNKKGD_03215 1.8e-19 L Transposase and inactivated derivatives
HKMNKKGD_03216 3.5e-66 3.6.4.12 L UvrD-like helicase C-terminal domain
HKMNKKGD_03217 8.7e-78 L DNA synthesis involved in DNA repair
HKMNKKGD_03218 3.4e-123 L Transposase and inactivated derivatives, IS30 family
HKMNKKGD_03219 1.7e-20 L Transposase and inactivated derivatives, IS30 family
HKMNKKGD_03220 4.6e-26
HKMNKKGD_03221 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HKMNKKGD_03222 7.4e-305 hsdM 2.1.1.72 V type I restriction-modification system
HKMNKKGD_03223 7.6e-68 3.1.21.3 V type I restriction modification DNA specificity domain
HKMNKKGD_03224 6.7e-196 L Psort location Cytoplasmic, score
HKMNKKGD_03225 2.4e-33
HKMNKKGD_03226 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKMNKKGD_03227 0.0 L MobA MobL family protein
HKMNKKGD_03228 3.7e-18
HKMNKKGD_03229 1.2e-42
HKMNKKGD_03230 2.5e-43 relB L Addiction module antitoxin, RelB DinJ family
HKMNKKGD_03231 9.8e-34 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HKMNKKGD_03232 2.2e-66 tnp2PF3 L Transposase
HKMNKKGD_03233 3.2e-36 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKMNKKGD_03234 7.8e-146 D CobQ CobB MinD ParA nucleotide binding domain protein
HKMNKKGD_03235 1.9e-59 S Family of unknown function (DUF5388)
HKMNKKGD_03236 6.3e-82 L Helix-turn-helix domain
HKMNKKGD_03237 4.6e-227 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
HKMNKKGD_03238 1.6e-71 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HKMNKKGD_03239 2.5e-217 L Transposase
HKMNKKGD_03240 7.5e-196 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HKMNKKGD_03241 2.9e-08 S Type II restriction endonuclease EcoO109I
HKMNKKGD_03242 1.2e-09 F SIR2-like domain
HKMNKKGD_03243 6.4e-43 K SIR2-like domain
HKMNKKGD_03246 5.8e-129 S FRG domain
HKMNKKGD_03247 3.9e-99 tnpR1 L Resolvase, N terminal domain
HKMNKKGD_03248 5e-252 fbp 3.1.3.11 G phosphatase activity
HKMNKKGD_03249 2.4e-302 kup P Transport of potassium into the cell
HKMNKKGD_03250 1.7e-31 L transposase and inactivated derivatives, IS30 family
HKMNKKGD_03251 1.2e-37 L Transposase and inactivated derivatives, IS30 family
HKMNKKGD_03252 1.9e-31
HKMNKKGD_03253 2.1e-11
HKMNKKGD_03255 2e-149 D CobQ CobB MinD ParA nucleotide binding domain protein
HKMNKKGD_03256 2.9e-35
HKMNKKGD_03257 3.7e-51 repA S Replication initiator protein A
HKMNKKGD_03258 1.6e-79 repA S Replication initiator protein A
HKMNKKGD_03259 2.1e-28
HKMNKKGD_03260 3.2e-123 S Fic/DOC family
HKMNKKGD_03261 9.8e-40
HKMNKKGD_03262 7.2e-27
HKMNKKGD_03263 0.0 L MobA MobL family protein
HKMNKKGD_03264 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKMNKKGD_03265 6.3e-18
HKMNKKGD_03266 4.3e-35 L Psort location Cytoplasmic, score
HKMNKKGD_03267 1.1e-150 L Psort location Cytoplasmic, score
HKMNKKGD_03268 2.7e-65 L Helix-turn-helix domain
HKMNKKGD_03269 2.5e-45 L hmm pf00665
HKMNKKGD_03270 2.3e-241 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
HKMNKKGD_03271 4.5e-228 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
HKMNKKGD_03272 7.8e-172 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKMNKKGD_03273 2.2e-217 G Belongs to the glycosyl hydrolase 1 family
HKMNKKGD_03274 1.6e-87 K Helix-turn-helix domain, rpiR family
HKMNKKGD_03275 1.4e-107
HKMNKKGD_03276 2.3e-212 O AAA domain (Cdc48 subfamily)
HKMNKKGD_03277 0.0 L MobA MobL family protein
HKMNKKGD_03278 2.7e-26
HKMNKKGD_03279 6.2e-42 relB L Addiction module antitoxin, RelB DinJ family
HKMNKKGD_03280 3.1e-50 repA S Replication initiator protein A
HKMNKKGD_03281 3.2e-36 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKMNKKGD_03282 1.7e-95 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HKMNKKGD_03283 5.1e-17
HKMNKKGD_03284 6e-133 L COG2801 Transposase and inactivated derivatives
HKMNKKGD_03285 9.8e-39 L Transposase and inactivated derivatives
HKMNKKGD_03286 4.9e-268 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKMNKKGD_03287 4e-156 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKMNKKGD_03288 2.6e-102 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HKMNKKGD_03289 1.3e-180 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HKMNKKGD_03290 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKMNKKGD_03291 1.1e-187 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HKMNKKGD_03292 5.9e-76 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKMNKKGD_03293 3.1e-56 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKMNKKGD_03294 6.9e-15 L Replication protein
HKMNKKGD_03295 9.4e-101 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HKMNKKGD_03296 6.1e-40
HKMNKKGD_03297 0.0 V Type II restriction enzyme, methylase subunits
HKMNKKGD_03298 1.2e-40 K Helix-turn-helix domain
HKMNKKGD_03299 2.8e-63 S Phage derived protein Gp49-like (DUF891)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)