ORF_ID e_value Gene_name EC_number CAZy COGs Description
HCFEABLD_00001 0.0 yhcA V MacB-like periplasmic core domain
HCFEABLD_00002 7.6e-107
HCFEABLD_00003 0.0 K PRD domain
HCFEABLD_00004 2.4e-62 S Domain of unknown function (DUF3284)
HCFEABLD_00005 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HCFEABLD_00006 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HCFEABLD_00007 6.1e-220 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCFEABLD_00008 6.1e-290 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCFEABLD_00009 4.4e-147 EGP Major facilitator Superfamily
HCFEABLD_00010 4e-56 EGP Major facilitator Superfamily
HCFEABLD_00011 2.7e-114 M ErfK YbiS YcfS YnhG
HCFEABLD_00012 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCFEABLD_00013 8.4e-284 ydfD K Alanine-glyoxylate amino-transferase
HCFEABLD_00014 4e-102 argO S LysE type translocator
HCFEABLD_00015 7.1e-214 arcT 2.6.1.1 E Aminotransferase
HCFEABLD_00016 4.4e-77 argR K Regulates arginine biosynthesis genes
HCFEABLD_00017 2.9e-12
HCFEABLD_00018 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HCFEABLD_00019 1e-54 yheA S Belongs to the UPF0342 family
HCFEABLD_00020 6.3e-232 yhaO L Ser Thr phosphatase family protein
HCFEABLD_00021 0.0 L AAA domain
HCFEABLD_00022 1.1e-186 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCFEABLD_00023 2.1e-216
HCFEABLD_00024 7.6e-91 3.4.21.102 M Peptidase family S41
HCFEABLD_00025 1.1e-56 3.4.21.102 M Peptidase family S41
HCFEABLD_00026 1.2e-177 K LysR substrate binding domain
HCFEABLD_00027 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
HCFEABLD_00028 0.0 1.3.5.4 C FAD binding domain
HCFEABLD_00029 1.7e-99
HCFEABLD_00030 3.5e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HCFEABLD_00031 7.6e-61 M domain protein
HCFEABLD_00032 8e-137 M domain protein
HCFEABLD_00033 4.8e-48 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HCFEABLD_00034 7.7e-56 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HCFEABLD_00035 3.2e-52 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HCFEABLD_00036 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
HCFEABLD_00037 1e-200 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCFEABLD_00038 2.1e-272 mutS L ATPase domain of DNA mismatch repair MUTS family
HCFEABLD_00039 1e-268 mutS L MutS domain V
HCFEABLD_00040 3.4e-183 ykoT GT2 M Glycosyl transferase family 2
HCFEABLD_00041 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCFEABLD_00042 4.8e-67 S NUDIX domain
HCFEABLD_00043 0.0 S membrane
HCFEABLD_00044 3.7e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HCFEABLD_00045 1.8e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HCFEABLD_00046 6.9e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HCFEABLD_00047 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HCFEABLD_00048 9.3e-106 GBS0088 S Nucleotidyltransferase
HCFEABLD_00049 1.4e-106
HCFEABLD_00050 5.1e-116 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HCFEABLD_00051 3.3e-112 K Bacterial regulatory proteins, tetR family
HCFEABLD_00052 9.4e-242 npr 1.11.1.1 C NADH oxidase
HCFEABLD_00053 0.0
HCFEABLD_00054 7.9e-61
HCFEABLD_00055 7.1e-192 S Fn3-like domain
HCFEABLD_00056 2e-102 S WxL domain surface cell wall-binding
HCFEABLD_00057 3.5e-78 S WxL domain surface cell wall-binding
HCFEABLD_00058 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCFEABLD_00059 2e-42
HCFEABLD_00060 9.9e-82 hit FG histidine triad
HCFEABLD_00061 1.6e-134 ecsA V ABC transporter, ATP-binding protein
HCFEABLD_00062 3.1e-223 ecsB U ABC transporter
HCFEABLD_00063 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HCFEABLD_00064 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCFEABLD_00065 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
HCFEABLD_00066 5.3e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCFEABLD_00067 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HCFEABLD_00068 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HCFEABLD_00069 7.9e-21 S Virus attachment protein p12 family
HCFEABLD_00070 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HCFEABLD_00071 1.3e-34 feoA P FeoA domain
HCFEABLD_00072 4.2e-144 sufC O FeS assembly ATPase SufC
HCFEABLD_00073 2.6e-244 sufD O FeS assembly protein SufD
HCFEABLD_00074 4.4e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCFEABLD_00075 1.6e-82 nifU C SUF system FeS assembly protein, NifU family
HCFEABLD_00076 1.4e-272 sufB O assembly protein SufB
HCFEABLD_00077 5.5e-45 yitW S Iron-sulfur cluster assembly protein
HCFEABLD_00078 2.3e-111 hipB K Helix-turn-helix
HCFEABLD_00079 4.5e-121 ybhL S Belongs to the BI1 family
HCFEABLD_00080 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCFEABLD_00081 1.3e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCFEABLD_00082 3e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCFEABLD_00083 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCFEABLD_00084 1.1e-248 dnaB L replication initiation and membrane attachment
HCFEABLD_00085 3.3e-172 dnaI L Primosomal protein DnaI
HCFEABLD_00086 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCFEABLD_00087 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCFEABLD_00088 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HCFEABLD_00089 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCFEABLD_00090 2.4e-55
HCFEABLD_00091 7.2e-239 yrvN L AAA C-terminal domain
HCFEABLD_00092 3.6e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HCFEABLD_00093 1e-62 hxlR K Transcriptional regulator, HxlR family
HCFEABLD_00094 1.3e-134 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HCFEABLD_00095 3.8e-251 pgaC GT2 M Glycosyl transferase
HCFEABLD_00096 1.3e-39
HCFEABLD_00097 1.4e-98 yqeG S HAD phosphatase, family IIIA
HCFEABLD_00098 2e-216 yqeH S Ribosome biogenesis GTPase YqeH
HCFEABLD_00099 1.1e-50 yhbY J RNA-binding protein
HCFEABLD_00100 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCFEABLD_00101 9.3e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HCFEABLD_00102 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCFEABLD_00103 4.4e-140 yqeM Q Methyltransferase
HCFEABLD_00104 4.9e-218 ylbM S Belongs to the UPF0348 family
HCFEABLD_00105 1.6e-97 yceD S Uncharacterized ACR, COG1399
HCFEABLD_00106 7e-88 S Peptidase propeptide and YPEB domain
HCFEABLD_00107 7.8e-169 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCFEABLD_00108 3e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCFEABLD_00109 1.9e-228 rarA L recombination factor protein RarA
HCFEABLD_00110 4.3e-121 K response regulator
HCFEABLD_00111 8e-307 arlS 2.7.13.3 T Histidine kinase
HCFEABLD_00112 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HCFEABLD_00113 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HCFEABLD_00114 5e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HCFEABLD_00115 8.4e-94 S SdpI/YhfL protein family
HCFEABLD_00116 1e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCFEABLD_00117 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HCFEABLD_00118 1e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCFEABLD_00119 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCFEABLD_00120 7.4e-64 yodB K Transcriptional regulator, HxlR family
HCFEABLD_00121 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCFEABLD_00122 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCFEABLD_00123 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HCFEABLD_00124 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
HCFEABLD_00125 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCFEABLD_00126 8.6e-96 liaI S membrane
HCFEABLD_00127 4e-75 XK27_02470 K LytTr DNA-binding domain
HCFEABLD_00128 1.5e-54 yneR S Belongs to the HesB IscA family
HCFEABLD_00129 0.0 S membrane
HCFEABLD_00130 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HCFEABLD_00131 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HCFEABLD_00132 1.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HCFEABLD_00133 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
HCFEABLD_00134 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
HCFEABLD_00135 4.9e-179 glk 2.7.1.2 G Glucokinase
HCFEABLD_00136 1e-108 pepE 3.4.13.21 E Belongs to the peptidase S51 family
HCFEABLD_00137 4.4e-68 yqhL P Rhodanese-like protein
HCFEABLD_00138 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
HCFEABLD_00139 1.7e-139 glpQ 3.1.4.46 C phosphodiesterase
HCFEABLD_00140 1e-173 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCFEABLD_00141 4.6e-64 glnR K Transcriptional regulator
HCFEABLD_00142 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
HCFEABLD_00143 2.5e-161
HCFEABLD_00144 4e-181
HCFEABLD_00145 6.2e-99 dut S Protein conserved in bacteria
HCFEABLD_00146 4.1e-56
HCFEABLD_00147 1.7e-30
HCFEABLD_00148 1.6e-123 L PFAM transposase IS116 IS110 IS902 family
HCFEABLD_00151 5.4e-19
HCFEABLD_00152 1.8e-89 K Transcriptional regulator
HCFEABLD_00153 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HCFEABLD_00154 3.2e-53 ysxB J Cysteine protease Prp
HCFEABLD_00155 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HCFEABLD_00156 1.6e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HCFEABLD_00157 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCFEABLD_00158 3.5e-74 yqhY S Asp23 family, cell envelope-related function
HCFEABLD_00159 5.2e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCFEABLD_00160 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCFEABLD_00161 9.3e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCFEABLD_00162 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCFEABLD_00163 6.1e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCFEABLD_00164 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HCFEABLD_00165 7.4e-77 argR K Regulates arginine biosynthesis genes
HCFEABLD_00166 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
HCFEABLD_00167 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
HCFEABLD_00168 1.2e-104 opuCB E ABC transporter permease
HCFEABLD_00169 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCFEABLD_00170 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
HCFEABLD_00171 4.5e-55
HCFEABLD_00172 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HCFEABLD_00173 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCFEABLD_00174 4e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCFEABLD_00175 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCFEABLD_00176 1.9e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCFEABLD_00177 1.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCFEABLD_00178 1.7e-134 stp 3.1.3.16 T phosphatase
HCFEABLD_00179 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HCFEABLD_00180 1.2e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCFEABLD_00181 2.8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HCFEABLD_00182 8.3e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
HCFEABLD_00183 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HCFEABLD_00184 1.8e-57 asp S Asp23 family, cell envelope-related function
HCFEABLD_00185 0.0 yloV S DAK2 domain fusion protein YloV
HCFEABLD_00186 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCFEABLD_00187 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCFEABLD_00188 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCFEABLD_00189 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCFEABLD_00190 0.0 smc D Required for chromosome condensation and partitioning
HCFEABLD_00191 5.6e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCFEABLD_00192 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HCFEABLD_00193 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCFEABLD_00194 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HCFEABLD_00195 2.6e-39 ylqC S Belongs to the UPF0109 family
HCFEABLD_00196 8.2e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCFEABLD_00197 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HCFEABLD_00198 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCFEABLD_00199 1.7e-51
HCFEABLD_00200 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HCFEABLD_00201 5.3e-86
HCFEABLD_00202 2.3e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HCFEABLD_00203 3.1e-271 XK27_00765
HCFEABLD_00205 5.8e-269 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
HCFEABLD_00206 3.3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
HCFEABLD_00207 1.2e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HCFEABLD_00208 9.6e-125 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HCFEABLD_00209 9.1e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HCFEABLD_00210 2.3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HCFEABLD_00211 1.1e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HCFEABLD_00212 5.3e-98 entB 3.5.1.19 Q Isochorismatase family
HCFEABLD_00213 1.8e-68 L Putative transposase of IS4/5 family (DUF4096)
HCFEABLD_00214 2e-76 L Transposase DDE domain
HCFEABLD_00215 2.6e-177 1.6.5.5 C Zinc-binding dehydrogenase
HCFEABLD_00216 6e-199 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HCFEABLD_00217 2.1e-58 S Protein of unknown function (DUF1648)
HCFEABLD_00219 8.6e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCFEABLD_00220 3.8e-179 yneE K Transcriptional regulator
HCFEABLD_00221 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCFEABLD_00222 2.9e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCFEABLD_00223 3.8e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCFEABLD_00224 2e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HCFEABLD_00225 1.2e-126 IQ reductase
HCFEABLD_00226 1.6e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCFEABLD_00227 2.3e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCFEABLD_00228 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HCFEABLD_00229 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HCFEABLD_00230 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCFEABLD_00231 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HCFEABLD_00232 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HCFEABLD_00233 4.9e-99 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HCFEABLD_00234 1.3e-123 S Protein of unknown function (DUF554)
HCFEABLD_00235 3.6e-160 K LysR substrate binding domain
HCFEABLD_00236 4.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
HCFEABLD_00237 1.7e-193 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCFEABLD_00238 2.3e-93 K transcriptional regulator
HCFEABLD_00239 8.6e-304 norB EGP Major Facilitator
HCFEABLD_00240 1.2e-139 f42a O Band 7 protein
HCFEABLD_00241 8.5e-54
HCFEABLD_00242 1.3e-28
HCFEABLD_00243 2.5e-209 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HCFEABLD_00244 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
HCFEABLD_00245 4.2e-46 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HCFEABLD_00246 7.9e-41
HCFEABLD_00247 1.9e-67 tspO T TspO/MBR family
HCFEABLD_00248 6.3e-76 uspA T Belongs to the universal stress protein A family
HCFEABLD_00249 8e-66 S Protein of unknown function (DUF805)
HCFEABLD_00250 4.1e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HCFEABLD_00251 3.5e-36
HCFEABLD_00252 3.1e-14
HCFEABLD_00253 6.5e-41 S transglycosylase associated protein
HCFEABLD_00254 4.8e-29 S CsbD-like
HCFEABLD_00255 9.4e-40
HCFEABLD_00256 8.6e-281 pipD E Dipeptidase
HCFEABLD_00257 5.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HCFEABLD_00258 5.7e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCFEABLD_00259 1e-170 2.5.1.74 H UbiA prenyltransferase family
HCFEABLD_00260 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
HCFEABLD_00261 1.9e-49
HCFEABLD_00262 2.4e-43
HCFEABLD_00263 5.6e-258 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCFEABLD_00264 1.4e-265 yfnA E Amino Acid
HCFEABLD_00265 1.2e-149 yitU 3.1.3.104 S hydrolase
HCFEABLD_00266 3.6e-268 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HCFEABLD_00267 1.2e-88 S Domain of unknown function (DUF4767)
HCFEABLD_00268 2.5e-250 malT G Major Facilitator
HCFEABLD_00269 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HCFEABLD_00270 1.1e-194 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HCFEABLD_00271 4.8e-196 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HCFEABLD_00272 2.9e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HCFEABLD_00273 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HCFEABLD_00274 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HCFEABLD_00275 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HCFEABLD_00276 2.1e-72 ypmB S protein conserved in bacteria
HCFEABLD_00277 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HCFEABLD_00278 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HCFEABLD_00279 1.3e-128 dnaD L Replication initiation and membrane attachment
HCFEABLD_00281 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCFEABLD_00282 7.7e-99 metI P ABC transporter permease
HCFEABLD_00283 2.7e-157 metQ_4 P Belongs to the nlpA lipoprotein family
HCFEABLD_00284 7.6e-83 uspA T Universal stress protein family
HCFEABLD_00285 7.8e-302 ftpA P Binding-protein-dependent transport system inner membrane component
HCFEABLD_00286 1.7e-182 ftpB P Bacterial extracellular solute-binding protein
HCFEABLD_00287 1.8e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
HCFEABLD_00288 1.2e-123 L PFAM transposase IS116 IS110 IS902 family
HCFEABLD_00289 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HCFEABLD_00290 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCFEABLD_00291 8.3e-110 ypsA S Belongs to the UPF0398 family
HCFEABLD_00292 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HCFEABLD_00294 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HCFEABLD_00295 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCFEABLD_00296 1.6e-123 L PFAM transposase IS116 IS110 IS902 family
HCFEABLD_00297 4.1e-226 P Major Facilitator Superfamily
HCFEABLD_00298 2.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HCFEABLD_00299 1.2e-73 S SnoaL-like domain
HCFEABLD_00300 1.8e-243 M Glycosyltransferase, group 2 family protein
HCFEABLD_00301 5.1e-209 mccF V LD-carboxypeptidase
HCFEABLD_00302 1.4e-78 K Acetyltransferase (GNAT) domain
HCFEABLD_00303 4.5e-239 M hydrolase, family 25
HCFEABLD_00304 1.4e-181 mccF 3.4.17.13 V LD-carboxypeptidase
HCFEABLD_00305 1.2e-124
HCFEABLD_00306 2.5e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
HCFEABLD_00307 2.5e-192
HCFEABLD_00308 3.4e-146 S hydrolase activity, acting on ester bonds
HCFEABLD_00309 3.2e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
HCFEABLD_00310 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
HCFEABLD_00311 9.6e-62 esbA S Family of unknown function (DUF5322)
HCFEABLD_00312 4.6e-294 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HCFEABLD_00313 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCFEABLD_00314 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCFEABLD_00315 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCFEABLD_00316 4.7e-207 carA 6.3.5.5 F Belongs to the CarA family
HCFEABLD_00317 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HCFEABLD_00318 6.4e-113 pgm5 G Phosphoglycerate mutase family
HCFEABLD_00319 5.8e-70 frataxin S Domain of unknown function (DU1801)
HCFEABLD_00321 1.1e-129 cat 2.3.1.28 V Chloramphenicol acetyltransferase
HCFEABLD_00322 3.5e-69 S LuxR family transcriptional regulator
HCFEABLD_00323 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
HCFEABLD_00325 1.2e-91 3.6.1.55 F NUDIX domain
HCFEABLD_00326 1.7e-162 V ABC transporter, ATP-binding protein
HCFEABLD_00327 1.3e-131 S ABC-2 family transporter protein
HCFEABLD_00328 0.0 FbpA K Fibronectin-binding protein
HCFEABLD_00329 1.9e-66 K Transcriptional regulator
HCFEABLD_00330 7e-161 degV S EDD domain protein, DegV family
HCFEABLD_00331 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HCFEABLD_00332 3.4e-132 S Protein of unknown function (DUF975)
HCFEABLD_00333 1.3e-09
HCFEABLD_00334 1.4e-49
HCFEABLD_00335 6.6e-150 2.7.7.12 C Domain of unknown function (DUF4931)
HCFEABLD_00336 4.6e-211 pmrB EGP Major facilitator Superfamily
HCFEABLD_00337 4.6e-12
HCFEABLD_00338 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HCFEABLD_00339 4.6e-129 yejC S Protein of unknown function (DUF1003)
HCFEABLD_00340 2.5e-134 XK27_00890 S Domain of unknown function (DUF368)
HCFEABLD_00341 2.1e-244 cycA E Amino acid permease
HCFEABLD_00342 4.5e-115
HCFEABLD_00343 4.1e-59
HCFEABLD_00344 1.1e-279 lldP C L-lactate permease
HCFEABLD_00345 3.9e-227
HCFEABLD_00346 3.3e-118 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HCFEABLD_00347 9.7e-194 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HCFEABLD_00348 6.8e-217 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCFEABLD_00349 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCFEABLD_00350 5.3e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HCFEABLD_00351 7.8e-76 mgrA K helix_turn_helix multiple antibiotic resistance protein
HCFEABLD_00352 4.6e-252 gshR1 1.8.1.7 C Glutathione reductase
HCFEABLD_00353 2.5e-65
HCFEABLD_00354 3.4e-244 M Glycosyl transferase family group 2
HCFEABLD_00355 1.2e-277 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCFEABLD_00356 1.8e-156 xerD L Phage integrase, N-terminal SAM-like domain
HCFEABLD_00357 4.2e-32 S YozE SAM-like fold
HCFEABLD_00358 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCFEABLD_00359 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HCFEABLD_00360 1.7e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
HCFEABLD_00361 1.2e-177 K Transcriptional regulator
HCFEABLD_00362 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCFEABLD_00363 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCFEABLD_00364 6.7e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCFEABLD_00365 2.2e-170 lacX 5.1.3.3 G Aldose 1-epimerase
HCFEABLD_00366 2.3e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HCFEABLD_00367 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HCFEABLD_00368 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HCFEABLD_00369 7.3e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HCFEABLD_00370 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCFEABLD_00371 3.3e-158 dprA LU DNA protecting protein DprA
HCFEABLD_00372 2e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCFEABLD_00373 1.8e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HCFEABLD_00375 1.4e-228 XK27_05470 E Methionine synthase
HCFEABLD_00376 2.3e-170 cpsY K Transcriptional regulator, LysR family
HCFEABLD_00377 5.1e-173 L restriction endonuclease
HCFEABLD_00378 2.5e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HCFEABLD_00379 7.4e-197 XK27_00915 C Luciferase-like monooxygenase
HCFEABLD_00380 3.3e-251 emrY EGP Major facilitator Superfamily
HCFEABLD_00381 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HCFEABLD_00382 3.4e-35 yozE S Belongs to the UPF0346 family
HCFEABLD_00383 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HCFEABLD_00384 1e-149 ypmR E GDSL-like Lipase/Acylhydrolase
HCFEABLD_00385 5.1e-148 DegV S EDD domain protein, DegV family
HCFEABLD_00386 2.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCFEABLD_00387 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCFEABLD_00388 0.0 yfmR S ABC transporter, ATP-binding protein
HCFEABLD_00389 9.6e-85
HCFEABLD_00390 2.5e-228 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCFEABLD_00391 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCFEABLD_00392 3.3e-149 3.1.3.102, 3.1.3.104 S hydrolase
HCFEABLD_00393 1.6e-214 S Tetratricopeptide repeat protein
HCFEABLD_00394 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCFEABLD_00395 2.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HCFEABLD_00396 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
HCFEABLD_00397 1.1e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HCFEABLD_00398 2e-19 M Lysin motif
HCFEABLD_00399 1.2e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HCFEABLD_00400 1.1e-195 ypbB 5.1.3.1 S Helix-turn-helix domain
HCFEABLD_00401 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCFEABLD_00402 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCFEABLD_00403 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCFEABLD_00404 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCFEABLD_00405 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCFEABLD_00406 1.1e-164 xerD D recombinase XerD
HCFEABLD_00407 2.9e-170 cvfB S S1 domain
HCFEABLD_00408 1.5e-74 yeaL S Protein of unknown function (DUF441)
HCFEABLD_00409 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HCFEABLD_00410 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HCFEABLD_00411 0.0 dnaE 2.7.7.7 L DNA polymerase
HCFEABLD_00412 7.3e-29 S Protein of unknown function (DUF2929)
HCFEABLD_00413 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCFEABLD_00414 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HCFEABLD_00415 1.4e-197 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCFEABLD_00416 1.6e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
HCFEABLD_00417 2.7e-151 M O-Antigen ligase
HCFEABLD_00418 8.5e-52 M O-Antigen ligase
HCFEABLD_00419 5.4e-120 drrB U ABC-2 type transporter
HCFEABLD_00420 7.1e-167 drrA V ABC transporter
HCFEABLD_00421 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
HCFEABLD_00422 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HCFEABLD_00423 1.6e-61 P Rhodanese Homology Domain
HCFEABLD_00424 2.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
HCFEABLD_00425 1.7e-207
HCFEABLD_00426 9.7e-79 I transferase activity, transferring acyl groups other than amino-acyl groups
HCFEABLD_00427 1.1e-123 I transferase activity, transferring acyl groups other than amino-acyl groups
HCFEABLD_00428 1.1e-181 C Zinc-binding dehydrogenase
HCFEABLD_00429 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
HCFEABLD_00430 6.8e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCFEABLD_00431 7.6e-242 EGP Major facilitator Superfamily
HCFEABLD_00432 4.3e-77 K Transcriptional regulator
HCFEABLD_00433 2.6e-211 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HCFEABLD_00434 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCFEABLD_00435 8e-137 K DeoR C terminal sensor domain
HCFEABLD_00436 1.7e-108 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
HCFEABLD_00437 3.5e-70 yneH 1.20.4.1 P ArsC family
HCFEABLD_00438 1.4e-68 S Protein of unknown function (DUF1722)
HCFEABLD_00439 1.2e-112 GM epimerase
HCFEABLD_00440 0.0 CP_1020 S Zinc finger, swim domain protein
HCFEABLD_00441 1.4e-119 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
HCFEABLD_00442 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HCFEABLD_00443 6.5e-128 K Helix-turn-helix domain, rpiR family
HCFEABLD_00444 1.4e-158 S Alpha beta hydrolase
HCFEABLD_00445 9e-113 GM NmrA-like family
HCFEABLD_00446 4.1e-77 S Uncharacterized protein conserved in bacteria (DUF2255)
HCFEABLD_00447 9.4e-161 K Transcriptional regulator
HCFEABLD_00448 1.6e-171 C nadph quinone reductase
HCFEABLD_00449 4.8e-14 S Alpha beta hydrolase
HCFEABLD_00450 8.7e-270 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCFEABLD_00451 1.2e-103 desR K helix_turn_helix, Lux Regulon
HCFEABLD_00452 5.5e-203 desK 2.7.13.3 T Histidine kinase
HCFEABLD_00453 3.8e-134 yvfS V ABC-2 type transporter
HCFEABLD_00454 2.2e-157 yvfR V ABC transporter
HCFEABLD_00456 6e-82 K Acetyltransferase (GNAT) domain
HCFEABLD_00457 2.8e-79 K MarR family
HCFEABLD_00458 3.8e-114 S Psort location CytoplasmicMembrane, score
HCFEABLD_00459 3.9e-162 V ABC transporter, ATP-binding protein
HCFEABLD_00460 9.8e-127 S ABC-2 family transporter protein
HCFEABLD_00461 3.6e-199
HCFEABLD_00462 3.5e-202
HCFEABLD_00463 4.8e-165 ytrB V ABC transporter, ATP-binding protein
HCFEABLD_00464 9.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
HCFEABLD_00465 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCFEABLD_00466 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCFEABLD_00467 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HCFEABLD_00468 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HCFEABLD_00469 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
HCFEABLD_00470 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCFEABLD_00471 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HCFEABLD_00472 6.6e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCFEABLD_00473 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
HCFEABLD_00474 4e-197 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HCFEABLD_00475 2.6e-71 yqeY S YqeY-like protein
HCFEABLD_00476 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HCFEABLD_00477 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCFEABLD_00478 2.5e-127 C Enoyl-(Acyl carrier protein) reductase
HCFEABLD_00479 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HCFEABLD_00480 2.9e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCFEABLD_00481 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCFEABLD_00482 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCFEABLD_00483 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HCFEABLD_00484 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
HCFEABLD_00485 1.9e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HCFEABLD_00486 7.8e-165 yniA G Fructosamine kinase
HCFEABLD_00487 7.9e-114 3.1.3.18 J HAD-hyrolase-like
HCFEABLD_00488 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCFEABLD_00489 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCFEABLD_00490 9.6e-58
HCFEABLD_00491 2.9e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HCFEABLD_00492 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
HCFEABLD_00493 3.6e-114 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HCFEABLD_00494 1.4e-49
HCFEABLD_00495 1.4e-49
HCFEABLD_00498 4e-127 3.6.4.12 L Belongs to the 'phage' integrase family
HCFEABLD_00499 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCFEABLD_00500 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HCFEABLD_00501 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCFEABLD_00502 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HCFEABLD_00503 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCFEABLD_00504 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
HCFEABLD_00505 4.4e-198 pbpX2 V Beta-lactamase
HCFEABLD_00506 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCFEABLD_00507 0.0 dnaK O Heat shock 70 kDa protein
HCFEABLD_00508 5.6e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCFEABLD_00509 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCFEABLD_00510 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HCFEABLD_00511 1.2e-188 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HCFEABLD_00512 9.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCFEABLD_00513 3.1e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HCFEABLD_00514 1.5e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HCFEABLD_00515 1.7e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HCFEABLD_00516 8.5e-93
HCFEABLD_00517 4.6e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HCFEABLD_00518 2.5e-264 ydiN 5.4.99.5 G Major Facilitator
HCFEABLD_00519 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCFEABLD_00520 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCFEABLD_00521 1.6e-46 ylxQ J ribosomal protein
HCFEABLD_00522 2.8e-48 ylxR K Protein of unknown function (DUF448)
HCFEABLD_00523 1.1e-217 nusA K Participates in both transcription termination and antitermination
HCFEABLD_00524 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
HCFEABLD_00525 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCFEABLD_00526 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCFEABLD_00527 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HCFEABLD_00528 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
HCFEABLD_00529 8.9e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCFEABLD_00530 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCFEABLD_00531 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HCFEABLD_00532 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCFEABLD_00533 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
HCFEABLD_00534 4.7e-134 S Haloacid dehalogenase-like hydrolase
HCFEABLD_00535 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCFEABLD_00536 2e-49 yazA L GIY-YIG catalytic domain protein
HCFEABLD_00537 2.8e-137 yabB 2.1.1.223 L Methyltransferase small domain
HCFEABLD_00538 6.4e-119 plsC 2.3.1.51 I Acyltransferase
HCFEABLD_00539 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
HCFEABLD_00540 2.9e-36 ynzC S UPF0291 protein
HCFEABLD_00541 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCFEABLD_00542 5.4e-86
HCFEABLD_00543 2.3e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HCFEABLD_00544 9.2e-76
HCFEABLD_00545 1.3e-66
HCFEABLD_00546 9.9e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
HCFEABLD_00549 2.1e-08 S Short C-terminal domain
HCFEABLD_00550 1.9e-25 S Short C-terminal domain
HCFEABLD_00552 2.9e-43 L HTH-like domain
HCFEABLD_00553 7.5e-36 L transposase activity
HCFEABLD_00554 6.5e-61 S Phage integrase family
HCFEABLD_00557 1.6e-31
HCFEABLD_00558 1.5e-143 Q Methyltransferase
HCFEABLD_00559 8.5e-57 ybjQ S Belongs to the UPF0145 family
HCFEABLD_00560 7.2e-212 EGP Major facilitator Superfamily
HCFEABLD_00561 1e-102 K Helix-turn-helix domain
HCFEABLD_00562 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCFEABLD_00563 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HCFEABLD_00564 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
HCFEABLD_00565 2.8e-140 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCFEABLD_00566 2.8e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HCFEABLD_00567 3.2e-46
HCFEABLD_00568 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCFEABLD_00569 1.5e-135 fruR K DeoR C terminal sensor domain
HCFEABLD_00570 1.8e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HCFEABLD_00571 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HCFEABLD_00572 1.8e-253 cpdA S Calcineurin-like phosphoesterase
HCFEABLD_00573 4.1e-262 cps4J S Polysaccharide biosynthesis protein
HCFEABLD_00574 2.7e-177 cps4I M Glycosyltransferase like family 2
HCFEABLD_00575 1.6e-233
HCFEABLD_00576 2.9e-190 cps4G M Glycosyltransferase Family 4
HCFEABLD_00577 1.2e-202 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
HCFEABLD_00578 7.9e-128 tuaA M Bacterial sugar transferase
HCFEABLD_00579 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
HCFEABLD_00580 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
HCFEABLD_00581 7.3e-124 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HCFEABLD_00582 6.4e-126 epsB M biosynthesis protein
HCFEABLD_00583 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCFEABLD_00584 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCFEABLD_00585 9.2e-270 glnPH2 P ABC transporter permease
HCFEABLD_00586 4.3e-22
HCFEABLD_00587 9.9e-73 S Iron-sulphur cluster biosynthesis
HCFEABLD_00588 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HCFEABLD_00589 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HCFEABLD_00590 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCFEABLD_00591 4.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCFEABLD_00592 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCFEABLD_00593 4.1e-159 S Tetratricopeptide repeat
HCFEABLD_00594 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCFEABLD_00595 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCFEABLD_00596 1.3e-192 mdtG EGP Major Facilitator Superfamily
HCFEABLD_00597 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCFEABLD_00598 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HCFEABLD_00599 0.0 L Transposase
HCFEABLD_00600 3.1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
HCFEABLD_00601 0.0 comEC S Competence protein ComEC
HCFEABLD_00602 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
HCFEABLD_00603 4.7e-126 comEA L Competence protein ComEA
HCFEABLD_00604 9.6e-197 ylbL T Belongs to the peptidase S16 family
HCFEABLD_00605 1.4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCFEABLD_00606 1.1e-101 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HCFEABLD_00607 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HCFEABLD_00608 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HCFEABLD_00609 1.6e-205 ftsW D Belongs to the SEDS family
HCFEABLD_00610 1.9e-273
HCFEABLD_00611 5.1e-259 ica2 GT2 M Glycosyl transferase family group 2
HCFEABLD_00612 1.2e-103
HCFEABLD_00613 4.1e-197
HCFEABLD_00614 0.0 typA T GTP-binding protein TypA
HCFEABLD_00615 2.4e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HCFEABLD_00616 3.3e-46 yktA S Belongs to the UPF0223 family
HCFEABLD_00617 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
HCFEABLD_00618 4.5e-266 lpdA 1.8.1.4 C Dehydrogenase
HCFEABLD_00619 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCFEABLD_00620 5.8e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HCFEABLD_00621 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HCFEABLD_00622 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCFEABLD_00623 1.6e-85
HCFEABLD_00624 3.1e-33 ykzG S Belongs to the UPF0356 family
HCFEABLD_00625 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCFEABLD_00626 2.2e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HCFEABLD_00627 1.7e-28
HCFEABLD_00628 5.5e-105 mltD CBM50 M NlpC P60 family protein
HCFEABLD_00629 0.0 L Transposase
HCFEABLD_00630 2.2e-171 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCFEABLD_00631 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HCFEABLD_00632 1.6e-120 S Repeat protein
HCFEABLD_00633 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HCFEABLD_00634 4e-197 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HCFEABLD_00635 5.5e-267 N domain, Protein
HCFEABLD_00636 1.7e-193 S Bacterial protein of unknown function (DUF916)
HCFEABLD_00637 2.3e-120 N WxL domain surface cell wall-binding
HCFEABLD_00638 2.6e-115 ktrA P domain protein
HCFEABLD_00639 1.3e-241 ktrB P Potassium uptake protein
HCFEABLD_00640 9.1e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCFEABLD_00641 4.9e-57 XK27_04120 S Putative amino acid metabolism
HCFEABLD_00642 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
HCFEABLD_00643 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCFEABLD_00644 4.6e-28
HCFEABLD_00645 5.6e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HCFEABLD_00646 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCFEABLD_00647 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCFEABLD_00648 1.2e-86 divIVA D DivIVA domain protein
HCFEABLD_00649 3.4e-146 ylmH S S4 domain protein
HCFEABLD_00650 1.2e-36 yggT S YGGT family
HCFEABLD_00651 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCFEABLD_00652 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCFEABLD_00653 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCFEABLD_00654 1.5e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HCFEABLD_00655 1.5e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCFEABLD_00656 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCFEABLD_00657 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCFEABLD_00658 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HCFEABLD_00659 7.5e-54 ftsL D Cell division protein FtsL
HCFEABLD_00660 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCFEABLD_00661 1.9e-77 mraZ K Belongs to the MraZ family
HCFEABLD_00662 1.9e-62 S Protein of unknown function (DUF3397)
HCFEABLD_00663 4.2e-175 corA P CorA-like Mg2+ transporter protein
HCFEABLD_00664 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HCFEABLD_00665 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCFEABLD_00666 6.3e-114 ywnB S NAD(P)H-binding
HCFEABLD_00667 8.3e-209 brnQ U Component of the transport system for branched-chain amino acids
HCFEABLD_00668 1.4e-30 3.4.13.21, 3.4.15.6 E Belongs to the peptidase S51 family
HCFEABLD_00669 1.1e-161 rrmA 2.1.1.187 H Methyltransferase
HCFEABLD_00670 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCFEABLD_00671 4.3e-206 XK27_05220 S AI-2E family transporter
HCFEABLD_00672 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HCFEABLD_00673 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HCFEABLD_00674 1.1e-115 cutC P Participates in the control of copper homeostasis
HCFEABLD_00675 8.9e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HCFEABLD_00676 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCFEABLD_00677 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
HCFEABLD_00678 3.6e-114 yjbH Q Thioredoxin
HCFEABLD_00679 0.0 pepF E oligoendopeptidase F
HCFEABLD_00680 7.6e-205 coiA 3.6.4.12 S Competence protein
HCFEABLD_00681 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HCFEABLD_00682 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCFEABLD_00683 3.8e-139 yhfI S Metallo-beta-lactamase superfamily
HCFEABLD_00684 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HCFEABLD_00694 5.5e-08
HCFEABLD_00706 1.5e-42 S COG NOG38524 non supervised orthologous group
HCFEABLD_00707 3.5e-64
HCFEABLD_00708 1.6e-75 yugI 5.3.1.9 J general stress protein
HCFEABLD_00709 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCFEABLD_00710 3e-119 dedA S SNARE-like domain protein
HCFEABLD_00711 1.2e-117 S Protein of unknown function (DUF1461)
HCFEABLD_00712 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCFEABLD_00713 1.5e-80 yutD S Protein of unknown function (DUF1027)
HCFEABLD_00714 1.5e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HCFEABLD_00715 4.4e-117 S Calcineurin-like phosphoesterase
HCFEABLD_00716 5.6e-253 cycA E Amino acid permease
HCFEABLD_00717 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCFEABLD_00718 3e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
HCFEABLD_00720 1.7e-87 S Prokaryotic N-terminal methylation motif
HCFEABLD_00721 8.6e-20
HCFEABLD_00722 5.5e-83 gspG NU general secretion pathway protein
HCFEABLD_00723 5.5e-43 comGC U competence protein ComGC
HCFEABLD_00724 3.7e-188 comGB NU type II secretion system
HCFEABLD_00725 5.6e-175 comGA NU Type II IV secretion system protein
HCFEABLD_00726 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCFEABLD_00727 8.3e-131 yebC K Transcriptional regulatory protein
HCFEABLD_00728 3e-48 S DsrE/DsrF-like family
HCFEABLD_00729 1.2e-163 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HCFEABLD_00730 1.9e-181 ccpA K catabolite control protein A
HCFEABLD_00731 2.4e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HCFEABLD_00732 1.5e-80 K helix_turn_helix, mercury resistance
HCFEABLD_00733 2.8e-56
HCFEABLD_00734 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HCFEABLD_00735 2.6e-158 ykuT M mechanosensitive ion channel
HCFEABLD_00736 1.1e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HCFEABLD_00737 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HCFEABLD_00738 6.5e-87 ykuL S (CBS) domain
HCFEABLD_00739 9.5e-97 S Phosphoesterase
HCFEABLD_00740 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCFEABLD_00741 9e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HCFEABLD_00742 7.6e-126 yslB S Protein of unknown function (DUF2507)
HCFEABLD_00743 3.3e-52 trxA O Belongs to the thioredoxin family
HCFEABLD_00744 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCFEABLD_00745 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HCFEABLD_00746 1.6e-48 yrzB S Belongs to the UPF0473 family
HCFEABLD_00747 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCFEABLD_00748 2.4e-43 yrzL S Belongs to the UPF0297 family
HCFEABLD_00749 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCFEABLD_00750 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HCFEABLD_00751 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HCFEABLD_00752 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCFEABLD_00753 2.8e-29 yajC U Preprotein translocase
HCFEABLD_00754 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCFEABLD_00755 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HCFEABLD_00756 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCFEABLD_00757 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCFEABLD_00758 9.6e-89
HCFEABLD_00759 0.0 S Bacterial membrane protein YfhO
HCFEABLD_00760 1.3e-72
HCFEABLD_00761 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCFEABLD_00762 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCFEABLD_00763 2.7e-154 ymdB S YmdB-like protein
HCFEABLD_00764 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
HCFEABLD_00765 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCFEABLD_00766 1.9e-231 cinA 3.5.1.42 S Belongs to the CinA family
HCFEABLD_00767 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCFEABLD_00768 5.7e-110 ymfM S Helix-turn-helix domain
HCFEABLD_00769 2.9e-251 ymfH S Peptidase M16
HCFEABLD_00770 3.2e-231 ymfF S Peptidase M16 inactive domain protein
HCFEABLD_00771 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
HCFEABLD_00772 5.6e-155 aatB ET ABC transporter substrate-binding protein
HCFEABLD_00773 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCFEABLD_00774 4.6e-109 glnP P ABC transporter permease
HCFEABLD_00775 1.2e-146 minD D Belongs to the ParA family
HCFEABLD_00776 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HCFEABLD_00777 1.2e-88 mreD M rod shape-determining protein MreD
HCFEABLD_00778 2.6e-144 mreC M Involved in formation and maintenance of cell shape
HCFEABLD_00779 2.8e-161 mreB D cell shape determining protein MreB
HCFEABLD_00780 1.3e-116 radC L DNA repair protein
HCFEABLD_00781 4.7e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HCFEABLD_00782 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCFEABLD_00783 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCFEABLD_00784 8e-235 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HCFEABLD_00785 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HCFEABLD_00786 4.9e-218 iscS2 2.8.1.7 E Aminotransferase class V
HCFEABLD_00788 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HCFEABLD_00789 1.1e-80 ytsP 1.8.4.14 T GAF domain-containing protein
HCFEABLD_00790 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCFEABLD_00791 5.2e-113 yktB S Belongs to the UPF0637 family
HCFEABLD_00792 2.5e-80 yueI S Protein of unknown function (DUF1694)
HCFEABLD_00793 7e-110 S Protein of unknown function (DUF1648)
HCFEABLD_00794 8.6e-44 czrA K Helix-turn-helix domain
HCFEABLD_00795 5.1e-232 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HCFEABLD_00796 9.2e-42 2.7.1.191 G PTS system fructose IIA component
HCFEABLD_00797 2e-104 G PTS system mannose fructose sorbose family IID component
HCFEABLD_00798 3.6e-103 G PTS system sorbose-specific iic component
HCFEABLD_00799 6e-66 2.7.1.191 G PTS system sorbose subfamily IIB component
HCFEABLD_00800 5.9e-95 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HCFEABLD_00801 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HCFEABLD_00802 8e-238 rarA L recombination factor protein RarA
HCFEABLD_00803 1.5e-38
HCFEABLD_00804 6.2e-82 usp6 T universal stress protein
HCFEABLD_00805 3.1e-201 bla2 3.5.2.6 V Beta-lactamase enzyme family
HCFEABLD_00806 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HCFEABLD_00807 4e-292 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HCFEABLD_00808 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HCFEABLD_00809 1.8e-187 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HCFEABLD_00810 1.6e-177 S Protein of unknown function (DUF2785)
HCFEABLD_00811 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
HCFEABLD_00812 2.2e-148 metQ M Belongs to the nlpA lipoprotein family
HCFEABLD_00813 4.1e-111 metI U ABC transporter permease
HCFEABLD_00814 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCFEABLD_00815 3.6e-48 gcsH2 E glycine cleavage
HCFEABLD_00816 9.3e-220 rodA D Belongs to the SEDS family
HCFEABLD_00817 3.3e-33 S Protein of unknown function (DUF2969)
HCFEABLD_00818 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HCFEABLD_00819 2.7e-180 mbl D Cell shape determining protein MreB Mrl
HCFEABLD_00820 2.1e-102 J Acetyltransferase (GNAT) domain
HCFEABLD_00821 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCFEABLD_00822 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HCFEABLD_00823 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCFEABLD_00824 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCFEABLD_00825 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCFEABLD_00826 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCFEABLD_00827 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCFEABLD_00828 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCFEABLD_00829 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HCFEABLD_00830 5e-232 pyrP F Permease
HCFEABLD_00831 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCFEABLD_00832 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCFEABLD_00833 6.9e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCFEABLD_00834 1e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCFEABLD_00835 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCFEABLD_00836 9.3e-109 tdk 2.7.1.21 F thymidine kinase
HCFEABLD_00837 1.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HCFEABLD_00838 5.9e-137 cobQ S glutamine amidotransferase
HCFEABLD_00839 9.8e-196 manA 5.3.1.8 G mannose-6-phosphate isomerase
HCFEABLD_00840 1.7e-190 ampC V Beta-lactamase
HCFEABLD_00841 1.4e-29
HCFEABLD_00842 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HCFEABLD_00843 1.9e-58
HCFEABLD_00844 5.3e-125
HCFEABLD_00845 0.0 yfiC V ABC transporter
HCFEABLD_00846 0.0 ycfI V ABC transporter, ATP-binding protein
HCFEABLD_00847 3.3e-65 S Protein of unknown function (DUF1093)
HCFEABLD_00848 3.8e-135 yxkH G Polysaccharide deacetylase
HCFEABLD_00850 1.6e-110
HCFEABLD_00852 3.3e-30 hol S Bacteriophage holin
HCFEABLD_00853 1.6e-48
HCFEABLD_00854 8e-176 M Glycosyl hydrolases family 25
HCFEABLD_00856 5.1e-70 S Protein of unknown function (DUF1617)
HCFEABLD_00857 0.0 sidC GT2,GT4 LM DNA recombination
HCFEABLD_00858 5.9e-61
HCFEABLD_00859 0.0 D NLP P60 protein
HCFEABLD_00860 1.7e-38
HCFEABLD_00861 3.3e-65
HCFEABLD_00862 8.7e-81 S Phage tail tube protein, TTP
HCFEABLD_00863 1.5e-59
HCFEABLD_00864 7.4e-103
HCFEABLD_00865 2.1e-63
HCFEABLD_00866 1.1e-53
HCFEABLD_00868 2e-175 S Phage major capsid protein E
HCFEABLD_00869 4.2e-48
HCFEABLD_00870 2.8e-16 S Domain of unknown function (DUF4355)
HCFEABLD_00872 2.4e-30
HCFEABLD_00873 3.6e-294 S Phage Mu protein F like protein
HCFEABLD_00874 7.4e-267 S Phage portal protein, SPP1 Gp6-like
HCFEABLD_00875 2.2e-240 ps334 S Terminase-like family
HCFEABLD_00876 7.8e-62 ps333 L Terminase small subunit
HCFEABLD_00877 1.8e-24 S Protein of unknown function (DUF2829)
HCFEABLD_00882 2.9e-81 arpU S Phage transcriptional regulator, ArpU family
HCFEABLD_00884 1.2e-64 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HCFEABLD_00885 5.3e-63
HCFEABLD_00886 8.3e-50
HCFEABLD_00887 1.6e-144 3.1.3.16 L DnaD domain protein
HCFEABLD_00888 1.8e-134 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HCFEABLD_00889 2e-150 recT L RecT family
HCFEABLD_00890 3.2e-69
HCFEABLD_00891 8.1e-13 S Domain of unknown function (DUF1508)
HCFEABLD_00893 8e-80
HCFEABLD_00894 2.9e-53
HCFEABLD_00897 5.8e-26 K Cro/C1-type HTH DNA-binding domain
HCFEABLD_00898 1.7e-37 K sequence-specific DNA binding
HCFEABLD_00900 1.3e-37 K Helix-turn-helix
HCFEABLD_00901 4.5e-61 yvaO K Helix-turn-helix domain
HCFEABLD_00902 1.1e-76 E IrrE N-terminal-like domain
HCFEABLD_00903 1.1e-133 J Domain of unknown function (DUF4041)
HCFEABLD_00904 2e-44 S Domain of unknown function (DUF5067)
HCFEABLD_00905 1e-51
HCFEABLD_00908 3.3e-64
HCFEABLD_00910 2.2e-42
HCFEABLD_00914 1.1e-45
HCFEABLD_00915 1.3e-105 S Domain of unknown function DUF1829
HCFEABLD_00916 1.6e-218 int L Belongs to the 'phage' integrase family
HCFEABLD_00918 8.9e-30
HCFEABLD_00920 2e-38
HCFEABLD_00921 1.4e-43
HCFEABLD_00922 0.0 L Transposase
HCFEABLD_00923 7.3e-83 K MarR family
HCFEABLD_00924 0.0 bztC D nuclear chromosome segregation
HCFEABLD_00925 6.1e-239 infB M MucBP domain
HCFEABLD_00926 2.7e-16
HCFEABLD_00927 7.2e-17
HCFEABLD_00928 5.2e-15
HCFEABLD_00929 1.1e-18
HCFEABLD_00930 1.6e-16
HCFEABLD_00931 1.6e-16
HCFEABLD_00932 1.6e-16
HCFEABLD_00933 1.9e-18
HCFEABLD_00934 1.6e-16
HCFEABLD_00935 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
HCFEABLD_00936 2.9e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HCFEABLD_00937 0.0 macB3 V ABC transporter, ATP-binding protein
HCFEABLD_00938 6.8e-24
HCFEABLD_00939 3.9e-259 pgi 5.3.1.9 G Belongs to the GPI family
HCFEABLD_00940 9.7e-155 glcU U sugar transport
HCFEABLD_00941 9.4e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
HCFEABLD_00942 2.9e-287 yclK 2.7.13.3 T Histidine kinase
HCFEABLD_00943 1.6e-134 K response regulator
HCFEABLD_00944 3e-243 XK27_08635 S UPF0210 protein
HCFEABLD_00945 2.3e-38 gcvR T Belongs to the UPF0237 family
HCFEABLD_00946 1.5e-169 EG EamA-like transporter family
HCFEABLD_00948 7.7e-92 S ECF-type riboflavin transporter, S component
HCFEABLD_00949 3.3e-47
HCFEABLD_00950 1e-207 yceI EGP Major facilitator Superfamily
HCFEABLD_00951 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
HCFEABLD_00952 3.8e-23
HCFEABLD_00954 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
HCFEABLD_00955 5.3e-172 ykfC 3.4.14.13 M NlpC/P60 family
HCFEABLD_00956 6.6e-81 K AsnC family
HCFEABLD_00957 2e-35
HCFEABLD_00958 5.1e-34
HCFEABLD_00959 1.7e-218 2.7.7.65 T diguanylate cyclase
HCFEABLD_00960 6.6e-295 S ABC transporter, ATP-binding protein
HCFEABLD_00961 2e-106 3.2.2.20 K acetyltransferase
HCFEABLD_00962 5.8e-82 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCFEABLD_00963 2.7e-39
HCFEABLD_00964 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HCFEABLD_00965 1.4e-189 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCFEABLD_00966 2.5e-161 degV S Uncharacterised protein, DegV family COG1307
HCFEABLD_00967 7.3e-231 hom1 1.1.1.3 E Homoserine dehydrogenase
HCFEABLD_00968 2.2e-243 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HCFEABLD_00969 4.8e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HCFEABLD_00970 1.4e-176 XK27_08835 S ABC transporter
HCFEABLD_00971 3.3e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HCFEABLD_00972 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
HCFEABLD_00973 5.7e-258 npr 1.11.1.1 C NADH oxidase
HCFEABLD_00974 1.5e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HCFEABLD_00975 4.8e-137 terC P membrane
HCFEABLD_00976 1.5e-84 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HCFEABLD_00977 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HCFEABLD_00978 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HCFEABLD_00979 2.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HCFEABLD_00980 3.8e-134 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HCFEABLD_00981 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HCFEABLD_00982 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HCFEABLD_00983 2.3e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HCFEABLD_00984 7.8e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HCFEABLD_00985 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HCFEABLD_00986 5.6e-214 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HCFEABLD_00987 6.5e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
HCFEABLD_00988 1.8e-215 ysaA V RDD family
HCFEABLD_00989 7.6e-166 corA P CorA-like Mg2+ transporter protein
HCFEABLD_00990 3.4e-50 S Domain of unknown function (DU1801)
HCFEABLD_00991 3.5e-13 rmeB K transcriptional regulator, MerR family
HCFEABLD_00992 8e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCFEABLD_00993 1.1e-186 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCFEABLD_00994 3.7e-34
HCFEABLD_00995 9.2e-112 S Protein of unknown function (DUF1211)
HCFEABLD_00996 0.0 ydgH S MMPL family
HCFEABLD_00997 3.3e-289 M domain protein
HCFEABLD_00998 3.9e-75 yjcF S Acetyltransferase (GNAT) domain
HCFEABLD_00999 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCFEABLD_01000 0.0 glpQ 3.1.4.46 C phosphodiesterase
HCFEABLD_01001 4e-197 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HCFEABLD_01002 2.3e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HCFEABLD_01003 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
HCFEABLD_01004 5.6e-181 3.6.4.13 S domain, Protein
HCFEABLD_01005 3.6e-168 S Polyphosphate kinase 2 (PPK2)
HCFEABLD_01006 2.5e-98 drgA C Nitroreductase family
HCFEABLD_01007 3.1e-178 iunH2 3.2.2.1 F nucleoside hydrolase
HCFEABLD_01008 3.4e-150 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCFEABLD_01009 3.7e-154 glcU U sugar transport
HCFEABLD_01010 2.1e-182 bglK_1 GK ROK family
HCFEABLD_01011 3.7e-156 pflC 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCFEABLD_01012 3.7e-134 yciT K DeoR C terminal sensor domain
HCFEABLD_01013 0.0 ybiW 2.3.1.54 C Pyruvate formate lyase-like
HCFEABLD_01014 9.1e-178 K sugar-binding domain protein
HCFEABLD_01015 7.4e-124 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
HCFEABLD_01016 4.2e-141 S Sucrose-6F-phosphate phosphohydrolase
HCFEABLD_01017 6.4e-176 ccpB 5.1.1.1 K lacI family
HCFEABLD_01018 3.6e-157 K Helix-turn-helix domain, rpiR family
HCFEABLD_01019 7.9e-177 S Oxidoreductase family, NAD-binding Rossmann fold
HCFEABLD_01020 5.9e-199 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
HCFEABLD_01021 0.0 yjcE P Sodium proton antiporter
HCFEABLD_01022 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCFEABLD_01023 3.7e-107 pncA Q Isochorismatase family
HCFEABLD_01024 1.4e-131
HCFEABLD_01025 5.1e-125 skfE V ABC transporter
HCFEABLD_01026 2.1e-64 yvoA_1 K Transcriptional regulator, GntR family
HCFEABLD_01027 2.1e-45 S Enterocin A Immunity
HCFEABLD_01028 7e-175 D Alpha beta
HCFEABLD_01029 0.0 pepF2 E Oligopeptidase F
HCFEABLD_01030 1.3e-72 K Transcriptional regulator
HCFEABLD_01031 3e-164
HCFEABLD_01033 0.0 L Transposase
HCFEABLD_01034 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCFEABLD_01035 1.9e-68
HCFEABLD_01036 1.9e-144 yjfP S Dienelactone hydrolase family
HCFEABLD_01037 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
HCFEABLD_01038 9.3e-206 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HCFEABLD_01039 5.2e-47
HCFEABLD_01040 6.3e-45
HCFEABLD_01041 5e-82 yybC S Protein of unknown function (DUF2798)
HCFEABLD_01042 1.7e-73
HCFEABLD_01043 4e-60
HCFEABLD_01044 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HCFEABLD_01045 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
HCFEABLD_01046 4.7e-79 uspA T universal stress protein
HCFEABLD_01047 8.7e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCFEABLD_01048 4.4e-20
HCFEABLD_01049 4.2e-44 S zinc-ribbon domain
HCFEABLD_01050 9.6e-70 S response to antibiotic
HCFEABLD_01051 1.7e-48 K Cro/C1-type HTH DNA-binding domain
HCFEABLD_01052 3.3e-21 S Protein of unknown function (DUF2929)
HCFEABLD_01053 7.9e-224 lsgC M Glycosyl transferases group 1
HCFEABLD_01054 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HCFEABLD_01055 1.5e-163 S Putative esterase
HCFEABLD_01056 2.4e-130 gntR2 K Transcriptional regulator
HCFEABLD_01057 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCFEABLD_01058 5.2e-139
HCFEABLD_01059 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCFEABLD_01060 5.5e-138 rrp8 K LytTr DNA-binding domain
HCFEABLD_01061 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
HCFEABLD_01062 7.7e-61
HCFEABLD_01063 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
HCFEABLD_01064 4.4e-58
HCFEABLD_01065 1.8e-240 yhdP S Transporter associated domain
HCFEABLD_01066 4.9e-87 nrdI F Belongs to the NrdI family
HCFEABLD_01067 2.9e-269 yjcE P Sodium proton antiporter
HCFEABLD_01068 1.1e-212 yttB EGP Major facilitator Superfamily
HCFEABLD_01069 8.6e-63 K helix_turn_helix, mercury resistance
HCFEABLD_01070 1.8e-173 C Zinc-binding dehydrogenase
HCFEABLD_01071 8.5e-57 S SdpI/YhfL protein family
HCFEABLD_01072 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCFEABLD_01073 1.2e-260 gabR K Bacterial regulatory proteins, gntR family
HCFEABLD_01074 5e-218 patA 2.6.1.1 E Aminotransferase
HCFEABLD_01075 2.3e-159 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCFEABLD_01076 3e-18
HCFEABLD_01077 1.7e-126 S membrane transporter protein
HCFEABLD_01078 1.9e-161 mleR K LysR family
HCFEABLD_01079 5.6e-115 ylbE GM NAD(P)H-binding
HCFEABLD_01080 8.2e-96 wecD K Acetyltransferase (GNAT) family
HCFEABLD_01081 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HCFEABLD_01082 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HCFEABLD_01083 4.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
HCFEABLD_01084 1.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCFEABLD_01085 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HCFEABLD_01086 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCFEABLD_01087 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HCFEABLD_01088 1.2e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HCFEABLD_01089 1.5e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCFEABLD_01090 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HCFEABLD_01091 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCFEABLD_01092 1e-298 pucR QT Purine catabolism regulatory protein-like family
HCFEABLD_01093 3.5e-236 pbuX F xanthine permease
HCFEABLD_01094 2.4e-221 pbuG S Permease family
HCFEABLD_01095 3.9e-162 GM NmrA-like family
HCFEABLD_01096 6.5e-156 T EAL domain
HCFEABLD_01097 2.6e-94
HCFEABLD_01098 9.2e-253 pgaC GT2 M Glycosyl transferase
HCFEABLD_01099 6.9e-124 2.1.1.14 E Methionine synthase
HCFEABLD_01100 6.4e-216 purD 6.3.4.13 F Belongs to the GARS family
HCFEABLD_01101 7.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HCFEABLD_01102 2.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HCFEABLD_01103 9.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HCFEABLD_01104 1.1e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCFEABLD_01105 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCFEABLD_01106 4.4e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCFEABLD_01107 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCFEABLD_01108 1.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HCFEABLD_01109 7.4e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCFEABLD_01110 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCFEABLD_01111 7.5e-196 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HCFEABLD_01112 7.9e-225 XK27_09615 1.3.5.4 S reductase
HCFEABLD_01113 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
HCFEABLD_01114 8.4e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HCFEABLD_01115 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HCFEABLD_01116 9.2e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HCFEABLD_01117 7.5e-149 S Alpha/beta hydrolase of unknown function (DUF915)
HCFEABLD_01118 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
HCFEABLD_01119 1.7e-139 cysA V ABC transporter, ATP-binding protein
HCFEABLD_01120 0.0 V FtsX-like permease family
HCFEABLD_01121 8e-42
HCFEABLD_01122 7.9e-61 gntR1 K Transcriptional regulator, GntR family
HCFEABLD_01123 6.9e-164 V ABC transporter, ATP-binding protein
HCFEABLD_01124 2.9e-148
HCFEABLD_01125 6.7e-81 uspA T universal stress protein
HCFEABLD_01126 1.2e-35
HCFEABLD_01127 4.2e-71 gtcA S Teichoic acid glycosylation protein
HCFEABLD_01128 4.3e-88
HCFEABLD_01129 2.7e-49
HCFEABLD_01131 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
HCFEABLD_01132 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
HCFEABLD_01133 5.4e-118
HCFEABLD_01134 1.5e-52
HCFEABLD_01136 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HCFEABLD_01137 3.6e-282 thrC 4.2.3.1 E Threonine synthase
HCFEABLD_01138 4.5e-146 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HCFEABLD_01139 1.5e-11 mcbG S Pentapeptide repeats (8 copies)
HCFEABLD_01140 1.7e-111 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HCFEABLD_01141 3.1e-101 3.6.1.13 L Belongs to the Nudix hydrolase family
HCFEABLD_01142 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
HCFEABLD_01143 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
HCFEABLD_01144 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
HCFEABLD_01145 8.4e-212 S Bacterial protein of unknown function (DUF871)
HCFEABLD_01146 2.1e-232 S Sterol carrier protein domain
HCFEABLD_01147 2.1e-225 EGP Major facilitator Superfamily
HCFEABLD_01148 2.1e-88 niaR S 3H domain
HCFEABLD_01149 2.3e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCFEABLD_01150 1.3e-117 K Transcriptional regulator
HCFEABLD_01151 3.2e-154 V ABC transporter
HCFEABLD_01152 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
HCFEABLD_01153 2.8e-246 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HCFEABLD_01154 3.4e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCFEABLD_01155 9.5e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCFEABLD_01156 5.1e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HCFEABLD_01157 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HCFEABLD_01158 1.8e-130 gntR K UTRA
HCFEABLD_01159 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
HCFEABLD_01160 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HCFEABLD_01161 1.8e-81
HCFEABLD_01162 9.8e-152 S hydrolase
HCFEABLD_01163 6.5e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCFEABLD_01164 8.3e-152 EG EamA-like transporter family
HCFEABLD_01165 1.3e-176 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HCFEABLD_01166 1.2e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HCFEABLD_01167 1.5e-233
HCFEABLD_01168 4.2e-77 fld C Flavodoxin
HCFEABLD_01169 0.0 M Bacterial Ig-like domain (group 3)
HCFEABLD_01170 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HCFEABLD_01171 2.7e-32
HCFEABLD_01172 8.3e-129 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
HCFEABLD_01173 2.2e-268 ycaM E amino acid
HCFEABLD_01174 7.9e-79 K Winged helix DNA-binding domain
HCFEABLD_01175 3.3e-166 S Oxidoreductase, aldo keto reductase family protein
HCFEABLD_01176 5.7e-163 akr5f 1.1.1.346 S reductase
HCFEABLD_01177 4.6e-163 K Transcriptional regulator
HCFEABLD_01179 1.5e-42 S COG NOG38524 non supervised orthologous group
HCFEABLD_01180 1.8e-84 hmpT S Pfam:DUF3816
HCFEABLD_01181 1e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCFEABLD_01182 3.9e-111
HCFEABLD_01183 2.4e-149 M Glycosyl hydrolases family 25
HCFEABLD_01184 5.9e-143 yvpB S Peptidase_C39 like family
HCFEABLD_01185 1.1e-92 yueI S Protein of unknown function (DUF1694)
HCFEABLD_01186 1.6e-115 S Protein of unknown function (DUF554)
HCFEABLD_01187 2.6e-149 KT helix_turn_helix, mercury resistance
HCFEABLD_01188 1.2e-123 L PFAM transposase IS116 IS110 IS902 family
HCFEABLD_01189 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCFEABLD_01190 6.6e-95 S Protein of unknown function (DUF1440)
HCFEABLD_01191 5.2e-174 hrtB V ABC transporter permease
HCFEABLD_01192 5.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HCFEABLD_01193 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
HCFEABLD_01194 1.4e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HCFEABLD_01195 8.1e-99 1.5.1.3 H RibD C-terminal domain
HCFEABLD_01196 4.1e-188 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCFEABLD_01197 7.5e-110 S Membrane
HCFEABLD_01198 1.2e-155 mleP3 S Membrane transport protein
HCFEABLD_01199 3.4e-258 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HCFEABLD_01200 7.6e-190 ynfM EGP Major facilitator Superfamily
HCFEABLD_01201 2.8e-125 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HCFEABLD_01202 1.1e-270 lmrB EGP Major facilitator Superfamily
HCFEABLD_01203 2e-75 S Domain of unknown function (DUF4811)
HCFEABLD_01204 1.8e-101 rimL J Acetyltransferase (GNAT) domain
HCFEABLD_01205 1.2e-172 S Conserved hypothetical protein 698
HCFEABLD_01206 3.7e-151 rlrG K Transcriptional regulator
HCFEABLD_01207 1.2e-296 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HCFEABLD_01208 6.9e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
HCFEABLD_01210 2.3e-52 lytE M LysM domain
HCFEABLD_01211 5.2e-92 ogt 2.1.1.63 L Methyltransferase
HCFEABLD_01212 3.6e-168 natA S ABC transporter, ATP-binding protein
HCFEABLD_01213 4.7e-211 natB CP ABC-2 family transporter protein
HCFEABLD_01214 1e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCFEABLD_01215 2.5e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
HCFEABLD_01216 3.2e-76 yphH S Cupin domain
HCFEABLD_01217 1.7e-78 K transcriptional regulator, MerR family
HCFEABLD_01218 2.3e-237 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HCFEABLD_01219 0.0 ylbB V ABC transporter permease
HCFEABLD_01220 7.5e-121 macB V ABC transporter, ATP-binding protein
HCFEABLD_01222 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCFEABLD_01223 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HCFEABLD_01224 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HCFEABLD_01225 2.4e-83
HCFEABLD_01226 7.3e-86 yvbK 3.1.3.25 K GNAT family
HCFEABLD_01227 7e-37
HCFEABLD_01228 8.2e-48
HCFEABLD_01229 1.2e-112 pgm8 G Histidine phosphatase superfamily (branch 1)
HCFEABLD_01230 8.4e-63 S Domain of unknown function (DUF4440)
HCFEABLD_01231 1.9e-158 K LysR substrate binding domain
HCFEABLD_01232 1.2e-103 GM NAD(P)H-binding
HCFEABLD_01233 2.3e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HCFEABLD_01234 3.2e-150 IQ Enoyl-(Acyl carrier protein) reductase
HCFEABLD_01235 1.1e-142 aRA11 1.1.1.346 S reductase
HCFEABLD_01236 1.3e-81 yiiE S Protein of unknown function (DUF1211)
HCFEABLD_01237 2.5e-76 darA C Flavodoxin
HCFEABLD_01238 3e-126 IQ reductase
HCFEABLD_01239 4.9e-82 glcU U sugar transport
HCFEABLD_01240 1.1e-86 GM NAD(P)H-binding
HCFEABLD_01241 5.6e-105 akr5f 1.1.1.346 S reductase
HCFEABLD_01242 2e-78 K Transcriptional regulator
HCFEABLD_01244 3e-25 fldA C Flavodoxin
HCFEABLD_01245 4.4e-10 adhR K helix_turn_helix, mercury resistance
HCFEABLD_01246 2.5e-114 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCFEABLD_01247 1.3e-130 C Aldo keto reductase
HCFEABLD_01248 1.5e-142 akr5f 1.1.1.346 S reductase
HCFEABLD_01249 1.3e-142 EGP Major Facilitator Superfamily
HCFEABLD_01250 5.7e-83 GM NAD(P)H-binding
HCFEABLD_01251 6.1e-76 T Belongs to the universal stress protein A family
HCFEABLD_01252 5.8e-95 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HCFEABLD_01253 8.9e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HCFEABLD_01254 1.7e-62
HCFEABLD_01255 9.2e-104 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HCFEABLD_01256 4.8e-221 patB 4.4.1.8 E Aminotransferase, class I
HCFEABLD_01257 1.9e-102 M Protein of unknown function (DUF3737)
HCFEABLD_01258 5.7e-194 C Aldo/keto reductase family
HCFEABLD_01260 0.0 mdlB V ABC transporter
HCFEABLD_01261 0.0 mdlA V ABC transporter
HCFEABLD_01262 3.3e-245 EGP Major facilitator Superfamily
HCFEABLD_01264 9.7e-194 yhgE V domain protein
HCFEABLD_01265 5.1e-96 K Transcriptional regulator (TetR family)
HCFEABLD_01266 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCFEABLD_01267 1.4e-138 endA F DNA RNA non-specific endonuclease
HCFEABLD_01268 1.4e-98 speG J Acetyltransferase (GNAT) domain
HCFEABLD_01269 1.1e-95 2.3.1.128 J Acetyltransferase (GNAT) domain
HCFEABLD_01270 3.9e-132 2.7.1.89 M Phosphotransferase enzyme family
HCFEABLD_01271 1.2e-219 S CAAX protease self-immunity
HCFEABLD_01272 3.2e-308 ybiT S ABC transporter, ATP-binding protein
HCFEABLD_01273 5.3e-147 3.1.3.102, 3.1.3.104 S hydrolase
HCFEABLD_01274 0.0 S Predicted membrane protein (DUF2207)
HCFEABLD_01275 0.0 uvrA3 L excinuclease ABC
HCFEABLD_01276 2.8e-208 EGP Major facilitator Superfamily
HCFEABLD_01277 7.6e-174 ropB K Helix-turn-helix XRE-family like proteins
HCFEABLD_01278 4.2e-177 pepR1 3.4.11.5 I Releases the N-terminal proline from various substrates
HCFEABLD_01279 3.1e-248 puuP_1 E Amino acid permease
HCFEABLD_01280 9.9e-233 yxiO S Vacuole effluxer Atg22 like
HCFEABLD_01281 3.6e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
HCFEABLD_01282 1.3e-159 I alpha/beta hydrolase fold
HCFEABLD_01283 1.1e-130 treR K UTRA
HCFEABLD_01284 1.9e-238
HCFEABLD_01285 5.6e-39 S Cytochrome B5
HCFEABLD_01286 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCFEABLD_01287 6.2e-218 2.7.7.65 T Diguanylate cyclase, GGDEF domain
HCFEABLD_01288 6.8e-127 yliE T EAL domain
HCFEABLD_01289 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCFEABLD_01290 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HCFEABLD_01291 2e-80
HCFEABLD_01292 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HCFEABLD_01293 6.8e-192 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCFEABLD_01294 1.5e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCFEABLD_01295 4.9e-22
HCFEABLD_01296 1.3e-78
HCFEABLD_01297 2.2e-165 K LysR substrate binding domain
HCFEABLD_01298 4e-243 P Sodium:sulfate symporter transmembrane region
HCFEABLD_01299 1.1e-286 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HCFEABLD_01300 2.1e-263 S response to antibiotic
HCFEABLD_01301 8.2e-134 S zinc-ribbon domain
HCFEABLD_01303 3.2e-37
HCFEABLD_01304 3.9e-114 aroD S Alpha/beta hydrolase family
HCFEABLD_01305 9.8e-176 S Phosphotransferase system, EIIC
HCFEABLD_01306 4.8e-268 I acetylesterase activity
HCFEABLD_01307 3.3e-224 sdrF M Collagen binding domain
HCFEABLD_01308 6.9e-159 yicL EG EamA-like transporter family
HCFEABLD_01309 4.4e-129 E lipolytic protein G-D-S-L family
HCFEABLD_01310 1.1e-177 4.1.1.52 S Amidohydrolase
HCFEABLD_01311 2.1e-111 K Transcriptional regulator C-terminal region
HCFEABLD_01312 1.4e-47 3.6.4.12 K HxlR-like helix-turn-helix
HCFEABLD_01313 1.1e-161 ypbG 2.7.1.2 GK ROK family
HCFEABLD_01314 0.0 lmrA 3.6.3.44 V ABC transporter
HCFEABLD_01315 1.1e-95 rmaB K Transcriptional regulator, MarR family
HCFEABLD_01316 1.3e-119 drgA C Nitroreductase family
HCFEABLD_01317 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HCFEABLD_01318 9e-119 cmpC S ATPases associated with a variety of cellular activities
HCFEABLD_01319 8.7e-155 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HCFEABLD_01320 1.6e-149 XK27_00670 S ABC transporter
HCFEABLD_01321 4.7e-261
HCFEABLD_01322 2.3e-63
HCFEABLD_01323 5.1e-190 S Cell surface protein
HCFEABLD_01324 3e-91 S WxL domain surface cell wall-binding
HCFEABLD_01325 2.4e-97 acuB S Domain in cystathionine beta-synthase and other proteins.
HCFEABLD_01326 7.3e-124 livF E ABC transporter
HCFEABLD_01327 1.8e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
HCFEABLD_01328 1.5e-140 livM E Branched-chain amino acid transport system / permease component
HCFEABLD_01329 6.5e-154 livH U Branched-chain amino acid transport system / permease component
HCFEABLD_01330 1.6e-211 livJ E Receptor family ligand binding region
HCFEABLD_01332 1.6e-123 L PFAM transposase IS116 IS110 IS902 family
HCFEABLD_01333 7e-33
HCFEABLD_01334 5e-113 zmp3 O Zinc-dependent metalloprotease
HCFEABLD_01335 2.8e-82 gtrA S GtrA-like protein
HCFEABLD_01336 3.2e-121 K Helix-turn-helix XRE-family like proteins
HCFEABLD_01337 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
HCFEABLD_01338 6.8e-72 T Belongs to the universal stress protein A family
HCFEABLD_01339 1.1e-46
HCFEABLD_01340 1.9e-116 S SNARE associated Golgi protein
HCFEABLD_01341 2e-49 K Transcriptional regulator, ArsR family
HCFEABLD_01342 7.5e-95 cadD P Cadmium resistance transporter
HCFEABLD_01343 0.0 yhcA V ABC transporter, ATP-binding protein
HCFEABLD_01344 0.0 P Concanavalin A-like lectin/glucanases superfamily
HCFEABLD_01345 7.4e-64
HCFEABLD_01346 3.4e-160 T Calcineurin-like phosphoesterase superfamily domain
HCFEABLD_01347 3.2e-55
HCFEABLD_01348 5.3e-150 dicA K Helix-turn-helix domain
HCFEABLD_01349 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCFEABLD_01350 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HCFEABLD_01351 2.7e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCFEABLD_01352 8.3e-281 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCFEABLD_01353 4.4e-186 1.1.1.219 GM Male sterility protein
HCFEABLD_01354 5.1e-75 K helix_turn_helix, mercury resistance
HCFEABLD_01355 8.1e-63 M LysM domain
HCFEABLD_01356 2.2e-93 M Lysin motif
HCFEABLD_01357 4.7e-108 S SdpI/YhfL protein family
HCFEABLD_01358 1.8e-54 nudA S ASCH
HCFEABLD_01359 1.2e-163 psaA P Belongs to the bacterial solute-binding protein 9 family
HCFEABLD_01360 2.7e-91
HCFEABLD_01361 7.6e-120 tag 3.2.2.20 L Methyladenine glycosylase
HCFEABLD_01362 9.7e-219 T diguanylate cyclase
HCFEABLD_01363 1.2e-73 S Psort location Cytoplasmic, score
HCFEABLD_01364 2.1e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HCFEABLD_01365 2.6e-166 K Bacterial regulatory helix-turn-helix protein, lysR family
HCFEABLD_01366 2e-73
HCFEABLD_01367 3.8e-131 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCFEABLD_01368 7.4e-176 C C4-dicarboxylate transmembrane transporter activity
HCFEABLD_01369 1.6e-117 GM NAD(P)H-binding
HCFEABLD_01370 4.7e-93 S Phosphatidylethanolamine-binding protein
HCFEABLD_01371 2.7e-78 yphH S Cupin domain
HCFEABLD_01372 3.7e-60 I sulfurtransferase activity
HCFEABLD_01373 6.6e-139 IQ reductase
HCFEABLD_01374 3.6e-117 GM NAD(P)H-binding
HCFEABLD_01375 1.9e-217 ykiI
HCFEABLD_01376 0.0 V ABC transporter
HCFEABLD_01377 4.8e-311 XK27_09600 V ABC transporter, ATP-binding protein
HCFEABLD_01378 9.1e-177 O protein import
HCFEABLD_01379 7.8e-227 amd 3.5.1.47 E Peptidase family M20/M25/M40
HCFEABLD_01380 7.7e-163 IQ KR domain
HCFEABLD_01382 2.5e-71
HCFEABLD_01383 1e-145 K Helix-turn-helix XRE-family like proteins
HCFEABLD_01384 9.6e-267 yjeM E Amino Acid
HCFEABLD_01385 1.3e-66 lysM M LysM domain
HCFEABLD_01386 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HCFEABLD_01387 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HCFEABLD_01388 0.0 ctpA 3.6.3.54 P P-type ATPase
HCFEABLD_01389 1.2e-42 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HCFEABLD_01390 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HCFEABLD_01391 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HCFEABLD_01392 6e-140 K Helix-turn-helix domain
HCFEABLD_01393 2.9e-38 S TfoX C-terminal domain
HCFEABLD_01394 3.5e-228 hpk9 2.7.13.3 T GHKL domain
HCFEABLD_01395 1.6e-261
HCFEABLD_01396 1.3e-75
HCFEABLD_01397 9.2e-187 S Cell surface protein
HCFEABLD_01398 1.7e-101 S WxL domain surface cell wall-binding
HCFEABLD_01399 1.7e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
HCFEABLD_01400 9.3e-68 S Iron-sulphur cluster biosynthesis
HCFEABLD_01401 6.5e-116 S GyrI-like small molecule binding domain
HCFEABLD_01402 1.6e-188 S Cell surface protein
HCFEABLD_01403 7.5e-101 S WxL domain surface cell wall-binding
HCFEABLD_01404 1.1e-62
HCFEABLD_01405 3.9e-213 NU Mycoplasma protein of unknown function, DUF285
HCFEABLD_01406 2.3e-116
HCFEABLD_01407 1.5e-115 S Haloacid dehalogenase-like hydrolase
HCFEABLD_01408 4.7e-57 K Transcriptional regulator PadR-like family
HCFEABLD_01409 3e-119 M1-1017
HCFEABLD_01410 2e-61 K Transcriptional regulator, HxlR family
HCFEABLD_01411 4.9e-213 ytbD EGP Major facilitator Superfamily
HCFEABLD_01412 3.2e-94 M ErfK YbiS YcfS YnhG
HCFEABLD_01413 0.0 asnB 6.3.5.4 E Asparagine synthase
HCFEABLD_01414 1.3e-134 K LytTr DNA-binding domain
HCFEABLD_01415 3e-205 2.7.13.3 T GHKL domain
HCFEABLD_01416 1.8e-99 fadR K Bacterial regulatory proteins, tetR family
HCFEABLD_01417 2.8e-168 GM NmrA-like family
HCFEABLD_01418 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HCFEABLD_01419 0.0 M Glycosyl hydrolases family 25
HCFEABLD_01420 1e-47 S Domain of unknown function (DUF1905)
HCFEABLD_01421 3.7e-63 hxlR K HxlR-like helix-turn-helix
HCFEABLD_01422 9.8e-132 ydfG S KR domain
HCFEABLD_01423 3.2e-98 K Bacterial regulatory proteins, tetR family
HCFEABLD_01424 3.5e-191 1.1.1.219 GM Male sterility protein
HCFEABLD_01425 4.1e-101 S Protein of unknown function (DUF1211)
HCFEABLD_01426 1.5e-180 S Aldo keto reductase
HCFEABLD_01427 1.2e-250 yfjF U Sugar (and other) transporter
HCFEABLD_01428 7.4e-109 K Bacterial regulatory proteins, tetR family
HCFEABLD_01429 4.4e-169 fhuD P Periplasmic binding protein
HCFEABLD_01430 4.2e-144 fhuC 3.6.3.34 HP ABC transporter
HCFEABLD_01431 9.5e-178 sirB U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCFEABLD_01432 1e-171 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCFEABLD_01433 5.4e-92 K Bacterial regulatory proteins, tetR family
HCFEABLD_01434 4.1e-164 GM NmrA-like family
HCFEABLD_01435 1.1e-30 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCFEABLD_01436 1.2e-160 yceJ EGP Major facilitator Superfamily
HCFEABLD_01437 1.6e-129 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCFEABLD_01438 3.7e-68 maa S transferase hexapeptide repeat
HCFEABLD_01439 1.1e-147 IQ Enoyl-(Acyl carrier protein) reductase
HCFEABLD_01440 2.3e-63 K helix_turn_helix, mercury resistance
HCFEABLD_01441 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HCFEABLD_01442 3e-174 S Bacterial protein of unknown function (DUF916)
HCFEABLD_01443 3.2e-85 S WxL domain surface cell wall-binding
HCFEABLD_01444 2.7e-156 NU Mycoplasma protein of unknown function, DUF285
HCFEABLD_01445 8.5e-09 NU Mycoplasma protein of unknown function, DUF285
HCFEABLD_01446 1.4e-116 K Bacterial regulatory proteins, tetR family
HCFEABLD_01447 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCFEABLD_01448 6.6e-290 yjcE P Sodium proton antiporter
HCFEABLD_01449 4.3e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HCFEABLD_01450 7.9e-163 K LysR substrate binding domain
HCFEABLD_01451 1.6e-282 1.3.5.4 C FAD binding domain
HCFEABLD_01452 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
HCFEABLD_01454 1.7e-84 dps P Belongs to the Dps family
HCFEABLD_01455 2.2e-115 K UTRA
HCFEABLD_01456 1.2e-269 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCFEABLD_01457 1.2e-247 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCFEABLD_01458 1.3e-63
HCFEABLD_01459 1.5e-11
HCFEABLD_01460 9.4e-41 4.1.1.44 S Carboxymuconolactone decarboxylase family
HCFEABLD_01461 2.2e-23 rmeD K helix_turn_helix, mercury resistance
HCFEABLD_01462 2.9e-63 S Protein of unknown function (DUF1093)
HCFEABLD_01463 4.3e-207 S Membrane
HCFEABLD_01464 1.1e-43 S Protein of unknown function (DUF3781)
HCFEABLD_01465 4e-107 ydeA S intracellular protease amidase
HCFEABLD_01466 8.3e-41 K HxlR-like helix-turn-helix
HCFEABLD_01467 3.3e-66
HCFEABLD_01468 1.3e-64 V ABC transporter
HCFEABLD_01469 2.3e-51 K Helix-turn-helix domain
HCFEABLD_01470 3.8e-204 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HCFEABLD_01471 5e-83 3.2.1.17, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCFEABLD_01472 1.2e-104 M ErfK YbiS YcfS YnhG
HCFEABLD_01473 2.3e-111 akr5f 1.1.1.346 S reductase
HCFEABLD_01474 3.7e-108 GM NAD(P)H-binding
HCFEABLD_01475 3.2e-77 3.5.4.1 GM SnoaL-like domain
HCFEABLD_01476 7.9e-258 qacA EGP Fungal trichothecene efflux pump (TRI12)
HCFEABLD_01477 9.2e-65 S Domain of unknown function (DUF4440)
HCFEABLD_01478 9.1e-104 K Bacterial regulatory proteins, tetR family
HCFEABLD_01479 2.3e-19 L HTH-like domain
HCFEABLD_01480 3.6e-32 L Integrase core domain
HCFEABLD_01482 6.8e-33 L transposase activity
HCFEABLD_01484 4.1e-07 mesE U HlyD family secretion protein
HCFEABLD_01486 5.9e-41 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HCFEABLD_01487 1.4e-32 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCFEABLD_01488 4e-28 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HCFEABLD_01489 1.8e-203 G system Galactitol-specific IIC component
HCFEABLD_01490 2.1e-70 rpiB 5.3.1.26, 5.3.1.34, 5.3.1.6 G Ribose/Galactose Isomerase
HCFEABLD_01491 9.3e-69 fruR K DeoR C terminal sensor domain
HCFEABLD_01492 3.2e-93 IQ Enoyl-(Acyl carrier protein) reductase
HCFEABLD_01493 1.7e-59 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HCFEABLD_01494 3.6e-85 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HCFEABLD_01495 2.1e-166 G system Galactitol-specific IIC component
HCFEABLD_01496 3.9e-26 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HCFEABLD_01497 5.5e-43 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCFEABLD_01498 4.2e-172 2.7.1.194, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCFEABLD_01499 3.3e-39 GM NAD(P)H-binding
HCFEABLD_01500 6.4e-35
HCFEABLD_01501 5.1e-112 Q Methyltransferase domain
HCFEABLD_01502 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCFEABLD_01503 1.9e-171 K AI-2E family transporter
HCFEABLD_01504 2.4e-190 xylR GK ROK family
HCFEABLD_01505 2.4e-83
HCFEABLD_01506 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HCFEABLD_01507 1e-162
HCFEABLD_01508 5e-201 KLT Protein tyrosine kinase
HCFEABLD_01509 2.9e-23 S Protein of unknown function (DUF4064)
HCFEABLD_01510 6e-97 S Domain of unknown function (DUF4352)
HCFEABLD_01511 3.9e-75 S Psort location Cytoplasmic, score
HCFEABLD_01512 4.1e-54
HCFEABLD_01513 3.6e-110 S membrane transporter protein
HCFEABLD_01514 2.3e-54 azlD S branched-chain amino acid
HCFEABLD_01515 5.1e-131 azlC E branched-chain amino acid
HCFEABLD_01516 1.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HCFEABLD_01517 4.9e-238 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HCFEABLD_01518 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
HCFEABLD_01519 3.2e-124 K response regulator
HCFEABLD_01520 5.5e-124 yoaK S Protein of unknown function (DUF1275)
HCFEABLD_01521 2.9e-160 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCFEABLD_01522 2.3e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCFEABLD_01523 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
HCFEABLD_01524 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCFEABLD_01525 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
HCFEABLD_01526 6.3e-157 spo0J K Belongs to the ParB family
HCFEABLD_01527 1.8e-136 soj D Sporulation initiation inhibitor
HCFEABLD_01528 2.7e-149 noc K Belongs to the ParB family
HCFEABLD_01529 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HCFEABLD_01530 4.1e-226 nupG F Nucleoside
HCFEABLD_01531 0.0 S Bacterial membrane protein YfhO
HCFEABLD_01532 3e-145 S Alpha/beta hydrolase of unknown function (DUF915)
HCFEABLD_01533 6.1e-168 K LysR substrate binding domain
HCFEABLD_01534 2.1e-235 EK Aminotransferase, class I
HCFEABLD_01535 1.8e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HCFEABLD_01536 6.9e-122 tcyB E ABC transporter
HCFEABLD_01537 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCFEABLD_01538 4.3e-128 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HCFEABLD_01539 1.1e-77 KT response to antibiotic
HCFEABLD_01540 1.5e-52 K Transcriptional regulator
HCFEABLD_01541 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
HCFEABLD_01542 1.7e-128 S Putative adhesin
HCFEABLD_01543 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
HCFEABLD_01544 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HCFEABLD_01545 1.4e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HCFEABLD_01546 1.3e-204 S DUF218 domain
HCFEABLD_01547 2e-127 ybbM S Uncharacterised protein family (UPF0014)
HCFEABLD_01548 3.6e-117 ybbL S ABC transporter, ATP-binding protein
HCFEABLD_01549 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCFEABLD_01550 9.4e-77
HCFEABLD_01551 2.2e-151 qorB 1.6.5.2 GM NmrA-like family
HCFEABLD_01552 1.1e-147 cof S haloacid dehalogenase-like hydrolase
HCFEABLD_01553 6e-79 merR K MerR family regulatory protein
HCFEABLD_01554 2.6e-155 1.6.5.2 GM NmrA-like family
HCFEABLD_01555 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HCFEABLD_01556 1.1e-126 magIII L Base excision DNA repair protein, HhH-GPD family
HCFEABLD_01557 1.4e-08
HCFEABLD_01558 2e-100 S NADPH-dependent FMN reductase
HCFEABLD_01559 3e-237 S module of peptide synthetase
HCFEABLD_01560 2.5e-104
HCFEABLD_01561 9.8e-88 perR P Belongs to the Fur family
HCFEABLD_01562 2.1e-58 S Enterocin A Immunity
HCFEABLD_01563 5.4e-36 S Phospholipase_D-nuclease N-terminal
HCFEABLD_01564 1.8e-169 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
HCFEABLD_01565 3.8e-104 J Acetyltransferase (GNAT) domain
HCFEABLD_01566 5.1e-64 lrgA S LrgA family
HCFEABLD_01567 7.3e-127 lrgB M LrgB-like family
HCFEABLD_01568 2.5e-145 DegV S EDD domain protein, DegV family
HCFEABLD_01569 4.1e-25
HCFEABLD_01570 3.5e-118 yugP S Putative neutral zinc metallopeptidase
HCFEABLD_01571 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
HCFEABLD_01572 7.4e-166 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
HCFEABLD_01573 1.7e-184 D Alpha beta
HCFEABLD_01574 7.1e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HCFEABLD_01575 8.1e-257 gor 1.8.1.7 C Glutathione reductase
HCFEABLD_01576 3.4e-55 S Enterocin A Immunity
HCFEABLD_01577 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCFEABLD_01578 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCFEABLD_01579 3.5e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCFEABLD_01580 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
HCFEABLD_01581 4.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCFEABLD_01583 6.2e-82
HCFEABLD_01584 3.6e-255 yhdG E C-terminus of AA_permease
HCFEABLD_01586 0.0 kup P Transport of potassium into the cell
HCFEABLD_01587 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCFEABLD_01588 3.1e-179 K AI-2E family transporter
HCFEABLD_01590 4e-189 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HCFEABLD_01591 4.4e-59 qacC P Small Multidrug Resistance protein
HCFEABLD_01592 1.1e-44 qacH U Small Multidrug Resistance protein
HCFEABLD_01593 3e-116 hly S protein, hemolysin III
HCFEABLD_01594 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HCFEABLD_01595 1.8e-159 czcD P cation diffusion facilitator family transporter
HCFEABLD_01596 7.8e-103 K Helix-turn-helix XRE-family like proteins
HCFEABLD_01598 2.6e-19
HCFEABLD_01599 1.2e-94 tag 3.2.2.20 L glycosylase
HCFEABLD_01600 6.8e-212 folP 2.5.1.15 H dihydropteroate synthase
HCFEABLD_01601 7.2e-101 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HCFEABLD_01602 1.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HCFEABLD_01603 3.4e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HCFEABLD_01604 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HCFEABLD_01605 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HCFEABLD_01606 4.7e-83 cvpA S Colicin V production protein
HCFEABLD_01607 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
HCFEABLD_01608 1.3e-249 EGP Major facilitator Superfamily
HCFEABLD_01610 1.2e-39
HCFEABLD_01611 1.5e-42 S COG NOG38524 non supervised orthologous group
HCFEABLD_01612 1.4e-95 V VanZ like family
HCFEABLD_01613 5e-195 blaA6 V Beta-lactamase
HCFEABLD_01614 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HCFEABLD_01615 6.7e-161 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCFEABLD_01616 5.1e-53 yitW S Pfam:DUF59
HCFEABLD_01617 5.9e-174 S Aldo keto reductase
HCFEABLD_01618 3.3e-97 FG HIT domain
HCFEABLD_01619 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
HCFEABLD_01620 1.4e-77
HCFEABLD_01621 6.2e-122 E GDSL-like Lipase/Acylhydrolase family
HCFEABLD_01622 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
HCFEABLD_01623 0.0 cadA P P-type ATPase
HCFEABLD_01625 2.2e-125 yyaQ S YjbR
HCFEABLD_01626 1.2e-123 L PFAM transposase IS116 IS110 IS902 family
HCFEABLD_01627 1.3e-221 S Uncharacterized protein conserved in bacteria (DUF2325)
HCFEABLD_01628 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HCFEABLD_01629 1.3e-199 frlB M SIS domain
HCFEABLD_01630 6.1e-27 3.2.2.10 S Belongs to the LOG family
HCFEABLD_01631 3.6e-255 nhaC C Na H antiporter NhaC
HCFEABLD_01632 2.4e-251 cycA E Amino acid permease
HCFEABLD_01633 2.4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HCFEABLD_01634 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HCFEABLD_01635 4.8e-162 azoB GM NmrA-like family
HCFEABLD_01636 1.6e-65 K Winged helix DNA-binding domain
HCFEABLD_01637 7e-71 spx4 1.20.4.1 P ArsC family
HCFEABLD_01638 1.7e-66 yeaO S Protein of unknown function, DUF488
HCFEABLD_01639 4e-53
HCFEABLD_01640 4.1e-214 mutY L A G-specific adenine glycosylase
HCFEABLD_01641 1.9e-62
HCFEABLD_01642 4.3e-86
HCFEABLD_01643 1.2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
HCFEABLD_01644 7e-56
HCFEABLD_01645 2.1e-14
HCFEABLD_01646 1.1e-115 GM NmrA-like family
HCFEABLD_01647 1.3e-81 elaA S GNAT family
HCFEABLD_01648 1.6e-158 EG EamA-like transporter family
HCFEABLD_01649 1.8e-119 S membrane
HCFEABLD_01650 1.4e-111 S VIT family
HCFEABLD_01651 4.8e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HCFEABLD_01652 0.0 copB 3.6.3.4 P P-type ATPase
HCFEABLD_01653 9.4e-74 copR K Copper transport repressor CopY TcrY
HCFEABLD_01654 7.4e-40
HCFEABLD_01655 1.2e-73 S COG NOG18757 non supervised orthologous group
HCFEABLD_01656 1.5e-248 lmrB EGP Major facilitator Superfamily
HCFEABLD_01657 1.7e-24
HCFEABLD_01658 4.2e-49
HCFEABLD_01659 1.6e-64 ycgX S Protein of unknown function (DUF1398)
HCFEABLD_01660 2.3e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HCFEABLD_01661 5.9e-214 mdtG EGP Major facilitator Superfamily
HCFEABLD_01662 6.8e-181 D Alpha beta
HCFEABLD_01663 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
HCFEABLD_01664 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HCFEABLD_01665 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HCFEABLD_01666 2.1e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HCFEABLD_01667 3.8e-152 ywkB S Membrane transport protein
HCFEABLD_01668 5.2e-164 yvgN C Aldo keto reductase
HCFEABLD_01669 9.2e-133 thrE S Putative threonine/serine exporter
HCFEABLD_01670 2e-77 S Threonine/Serine exporter, ThrE
HCFEABLD_01671 2.3e-43 S Protein of unknown function (DUF1093)
HCFEABLD_01672 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HCFEABLD_01673 2.7e-91 ymdB S Macro domain protein
HCFEABLD_01674 3.4e-95 K transcriptional regulator
HCFEABLD_01675 5.5e-50 yvlA
HCFEABLD_01676 6e-161 ypuA S Protein of unknown function (DUF1002)
HCFEABLD_01677 0.0
HCFEABLD_01678 5.8e-186 S Bacterial protein of unknown function (DUF916)
HCFEABLD_01679 1.7e-129 S WxL domain surface cell wall-binding
HCFEABLD_01680 1.9e-135 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HCFEABLD_01681 3.5e-88 K Winged helix DNA-binding domain
HCFEABLD_01682 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
HCFEABLD_01683 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HCFEABLD_01684 1.8e-27
HCFEABLD_01685 2.5e-285 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HCFEABLD_01686 1.6e-74 mltD CBM50 M PFAM NLP P60 protein
HCFEABLD_01687 3.3e-50
HCFEABLD_01688 3.5e-61
HCFEABLD_01691 9.4e-183 yfeX P Peroxidase
HCFEABLD_01692 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HCFEABLD_01693 2.4e-127 ydcF S Gram-negative-bacterium-type cell wall biogenesis
HCFEABLD_01694 1.5e-183 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HCFEABLD_01695 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HCFEABLD_01696 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HCFEABLD_01697 9.5e-55 txlA O Thioredoxin-like domain
HCFEABLD_01698 5.6e-40 yrkD S Metal-sensitive transcriptional repressor
HCFEABLD_01699 1.6e-18
HCFEABLD_01700 1.2e-94 dps P Belongs to the Dps family
HCFEABLD_01701 1.6e-32 copZ P Heavy-metal-associated domain
HCFEABLD_01702 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HCFEABLD_01703 0.0 pepO 3.4.24.71 O Peptidase family M13
HCFEABLD_01704 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HCFEABLD_01705 1.3e-262 nox C NADH oxidase
HCFEABLD_01706 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HCFEABLD_01707 6.1e-164 S Cell surface protein
HCFEABLD_01708 1.5e-118 S WxL domain surface cell wall-binding
HCFEABLD_01709 2.3e-99 S WxL domain surface cell wall-binding
HCFEABLD_01710 2.3e-44
HCFEABLD_01711 5.4e-104 K Bacterial regulatory proteins, tetR family
HCFEABLD_01712 1.5e-49
HCFEABLD_01713 1.4e-248 S Putative metallopeptidase domain
HCFEABLD_01714 2.4e-220 3.1.3.1 S associated with various cellular activities
HCFEABLD_01715 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
HCFEABLD_01716 0.0 ubiB S ABC1 family
HCFEABLD_01717 1.3e-249 brnQ U Component of the transport system for branched-chain amino acids
HCFEABLD_01718 0.0 lacS G Transporter
HCFEABLD_01719 0.0 lacA 3.2.1.23 G -beta-galactosidase
HCFEABLD_01720 1.6e-188 lacR K Transcriptional regulator
HCFEABLD_01721 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HCFEABLD_01722 3.6e-230 mdtH P Sugar (and other) transporter
HCFEABLD_01723 2.3e-303 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HCFEABLD_01724 8.6e-232 EGP Major facilitator Superfamily
HCFEABLD_01725 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
HCFEABLD_01726 5e-100 fic D Fic/DOC family
HCFEABLD_01727 4.7e-76 K Helix-turn-helix XRE-family like proteins
HCFEABLD_01728 2e-183 galR K Transcriptional regulator
HCFEABLD_01729 4.2e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HCFEABLD_01730 8.9e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HCFEABLD_01731 9.3e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HCFEABLD_01732 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HCFEABLD_01733 8.3e-187 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HCFEABLD_01734 0.0 rafA 3.2.1.22 G alpha-galactosidase
HCFEABLD_01735 0.0 lacS G Transporter
HCFEABLD_01736 4.2e-197 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HCFEABLD_01737 1.1e-173 galR K Transcriptional regulator
HCFEABLD_01738 2.6e-194 C Aldo keto reductase family protein
HCFEABLD_01739 2.4e-65 S pyridoxamine 5-phosphate
HCFEABLD_01740 0.0 1.3.5.4 C FAD binding domain
HCFEABLD_01741 6.1e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCFEABLD_01742 1.1e-130 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HCFEABLD_01743 1.2e-214 ydiM G Transporter
HCFEABLD_01744 4.2e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCFEABLD_01745 2.9e-162 K Transcriptional regulator, LysR family
HCFEABLD_01746 6.7e-210 ydiN G Major Facilitator Superfamily
HCFEABLD_01747 7.6e-64
HCFEABLD_01748 1.8e-155 estA S Putative esterase
HCFEABLD_01749 1.2e-134 K UTRA domain
HCFEABLD_01750 3.6e-249 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCFEABLD_01751 3e-165 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HCFEABLD_01752 1.9e-161 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HCFEABLD_01753 1.7e-212 S Bacterial protein of unknown function (DUF871)
HCFEABLD_01754 1e-292 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCFEABLD_01755 2.4e-33 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
HCFEABLD_01756 1.6e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HCFEABLD_01757 2.1e-110 6.2.1.3 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HCFEABLD_01758 2.6e-39 ygcQ C Electron transfer flavoprotein FAD-binding domain
HCFEABLD_01759 1.8e-22 fixA C Electron transfer flavoprotein domain
HCFEABLD_01760 1.3e-149 I Acyl-CoA dehydrogenase, C-terminal domain
HCFEABLD_01761 9.1e-170 MA20_04610 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HCFEABLD_01762 3.6e-187 I Acyl-CoA dehydrogenase, N-terminal domain
HCFEABLD_01763 1.5e-135 oxlT G Major Facilitator Superfamily
HCFEABLD_01764 1.2e-65 K Transcriptional regulator, LysR family
HCFEABLD_01765 1.9e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCFEABLD_01766 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
HCFEABLD_01767 3.8e-159 licT K CAT RNA binding domain
HCFEABLD_01768 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
HCFEABLD_01769 2.1e-174 K Transcriptional regulator, LacI family
HCFEABLD_01770 6.1e-271 G Major Facilitator
HCFEABLD_01771 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HCFEABLD_01773 5.8e-188 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCFEABLD_01774 2.7e-146 yxeH S hydrolase
HCFEABLD_01775 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCFEABLD_01776 2e-115 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HCFEABLD_01777 9.8e-242 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HCFEABLD_01778 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
HCFEABLD_01779 6.7e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCFEABLD_01780 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCFEABLD_01781 1.3e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
HCFEABLD_01782 1.4e-187 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HCFEABLD_01783 5.1e-113 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HCFEABLD_01784 1.6e-193 gatC G PTS system sugar-specific permease component
HCFEABLD_01785 2.3e-34 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HCFEABLD_01786 9.7e-56 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCFEABLD_01787 9.8e-90 K DeoR C terminal sensor domain
HCFEABLD_01788 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HCFEABLD_01789 2.6e-70 yueI S Protein of unknown function (DUF1694)
HCFEABLD_01790 8.2e-102 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HCFEABLD_01791 1.3e-265 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HCFEABLD_01792 3.9e-136 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HCFEABLD_01793 2.7e-307 araB 2.7.1.12, 2.7.1.16, 2.7.1.5 G carbohydrate kinase FGGY
HCFEABLD_01794 1.6e-255 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HCFEABLD_01795 1.4e-206 araR K Transcriptional regulator
HCFEABLD_01796 7.4e-136 K Helix-turn-helix domain, rpiR family
HCFEABLD_01797 3.7e-72 yueI S Protein of unknown function (DUF1694)
HCFEABLD_01798 1.3e-164 I alpha/beta hydrolase fold
HCFEABLD_01799 1.5e-160 I alpha/beta hydrolase fold
HCFEABLD_01800 2.6e-272 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCFEABLD_01801 5.2e-207 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCFEABLD_01802 1.9e-135 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
HCFEABLD_01803 5.2e-156 nanK GK ROK family
HCFEABLD_01804 6.2e-165 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HCFEABLD_01805 9.3e-124 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HCFEABLD_01806 2.1e-227 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
HCFEABLD_01807 4.2e-70 S Pyrimidine dimer DNA glycosylase
HCFEABLD_01808 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
HCFEABLD_01809 3e-10
HCFEABLD_01810 9e-13 ytgB S Transglycosylase associated protein
HCFEABLD_01811 1.9e-291 katA 1.11.1.6 C Belongs to the catalase family
HCFEABLD_01812 4.9e-78 yneH 1.20.4.1 K ArsC family
HCFEABLD_01813 2.8e-134 K LytTr DNA-binding domain
HCFEABLD_01814 8.7e-160 2.7.13.3 T GHKL domain
HCFEABLD_01815 1.8e-12
HCFEABLD_01816 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HCFEABLD_01817 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
HCFEABLD_01819 6.1e-202 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HCFEABLD_01820 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCFEABLD_01821 8.7e-72 K Transcriptional regulator
HCFEABLD_01822 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCFEABLD_01823 4.2e-71 yueI S Protein of unknown function (DUF1694)
HCFEABLD_01824 1e-125 S Membrane
HCFEABLD_01825 1.2e-165 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HCFEABLD_01826 1.3e-256 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HCFEABLD_01827 5e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HCFEABLD_01828 1.8e-286 rhaB 2.7.1.12, 2.7.1.16, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HCFEABLD_01829 4.6e-244 iolF EGP Major facilitator Superfamily
HCFEABLD_01830 1.9e-178 rhaR K helix_turn_helix, arabinose operon control protein
HCFEABLD_01831 2.1e-140 K DeoR C terminal sensor domain
HCFEABLD_01832 4.2e-80 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCFEABLD_01833 3.3e-52 sgcB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HCFEABLD_01834 3.2e-249 pts36C G PTS system sugar-specific permease component
HCFEABLD_01836 1.6e-134 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HCFEABLD_01837 2.8e-260 iolT EGP Major facilitator Superfamily
HCFEABLD_01838 1.7e-198 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HCFEABLD_01839 1.7e-201 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HCFEABLD_01840 5e-178 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HCFEABLD_01841 4.2e-197 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HCFEABLD_01842 5e-268 iolT EGP Major facilitator Superfamily
HCFEABLD_01843 9.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HCFEABLD_01844 7.8e-82 S Haem-degrading
HCFEABLD_01845 2.1e-171 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
HCFEABLD_01846 1.6e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HCFEABLD_01847 1.5e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HCFEABLD_01848 1e-116 L PFAM Integrase, catalytic core
HCFEABLD_01849 8.5e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HCFEABLD_01850 6.5e-174 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HCFEABLD_01851 6.3e-102 srlA G PTS system enzyme II sorbitol-specific factor
HCFEABLD_01852 9.2e-92 gutM K Glucitol operon activator protein (GutM)
HCFEABLD_01853 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HCFEABLD_01854 5.5e-145 IQ NAD dependent epimerase/dehydratase family
HCFEABLD_01855 5.9e-287 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCFEABLD_01856 1.3e-159 ypbG 2.7.1.2 GK ROK family
HCFEABLD_01857 0.0 mngB 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HCFEABLD_01858 3.1e-253 S Metal-independent alpha-mannosidase (GH125)
HCFEABLD_01859 2.7e-194 rliB K Transcriptional regulator
HCFEABLD_01860 0.0 ypdD G Glycosyl hydrolase family 92
HCFEABLD_01861 9.1e-217 msmX P Belongs to the ABC transporter superfamily
HCFEABLD_01862 8e-165 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HCFEABLD_01863 1.5e-269 yesN K helix_turn_helix, arabinose operon control protein
HCFEABLD_01864 0.0 yesM 2.7.13.3 T Histidine kinase
HCFEABLD_01865 4.1e-107 ypcB S integral membrane protein
HCFEABLD_01866 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HCFEABLD_01867 9.8e-280 G Domain of unknown function (DUF3502)
HCFEABLD_01868 1.5e-161 lplC U Binding-protein-dependent transport system inner membrane component
HCFEABLD_01869 5.2e-181 U Binding-protein-dependent transport system inner membrane component
HCFEABLD_01870 0.0 3.2.1.52 GH20 G Glycosyl hydrolase family 20, catalytic domain
HCFEABLD_01871 8.5e-156 K AraC-like ligand binding domain
HCFEABLD_01872 0.0 mdlA2 V ABC transporter
HCFEABLD_01873 0.0 yknV V ABC transporter
HCFEABLD_01874 2.2e-193 rliB K helix_turn_helix gluconate operon transcriptional repressor
HCFEABLD_01875 6.8e-156 lrp QT PucR C-terminal helix-turn-helix domain
HCFEABLD_01876 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HCFEABLD_01877 1e-174 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HCFEABLD_01878 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
HCFEABLD_01879 2.5e-86 gutM K Glucitol operon activator protein (GutM)
HCFEABLD_01880 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HCFEABLD_01881 1.5e-144 IQ NAD dependent epimerase/dehydratase family
HCFEABLD_01882 2.7e-160 rbsU U ribose uptake protein RbsU
HCFEABLD_01883 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HCFEABLD_01884 2.3e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCFEABLD_01885 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
HCFEABLD_01886 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HCFEABLD_01887 1.5e-196 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HCFEABLD_01888 2.7e-79 T Universal stress protein family
HCFEABLD_01889 2.2e-99 padR K Virulence activator alpha C-term
HCFEABLD_01890 1.7e-104 padC Q Phenolic acid decarboxylase
HCFEABLD_01891 6.7e-142 tesE Q hydratase
HCFEABLD_01892 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
HCFEABLD_01893 1.2e-157 degV S DegV family
HCFEABLD_01894 9.3e-58 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
HCFEABLD_01895 1.5e-255 pepC 3.4.22.40 E aminopeptidase
HCFEABLD_01897 3.6e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HCFEABLD_01898 1.1e-302
HCFEABLD_01900 4.7e-159 S Bacterial protein of unknown function (DUF916)
HCFEABLD_01901 6.9e-93 S Cell surface protein
HCFEABLD_01902 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCFEABLD_01903 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCFEABLD_01904 2.5e-130 jag S R3H domain protein
HCFEABLD_01905 9.3e-239 Q Imidazolonepropionase and related amidohydrolases
HCFEABLD_01906 7.7e-310 E ABC transporter, substratebinding protein
HCFEABLD_01907 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCFEABLD_01908 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCFEABLD_01909 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCFEABLD_01910 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCFEABLD_01911 5e-37 yaaA S S4 domain protein YaaA
HCFEABLD_01912 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCFEABLD_01913 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCFEABLD_01914 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCFEABLD_01915 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HCFEABLD_01916 6.8e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HCFEABLD_01917 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCFEABLD_01918 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HCFEABLD_01919 1.4e-67 rplI J Binds to the 23S rRNA
HCFEABLD_01920 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HCFEABLD_01921 8.8e-226 yttB EGP Major facilitator Superfamily
HCFEABLD_01922 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCFEABLD_01923 4.3e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCFEABLD_01925 1.9e-276 E ABC transporter, substratebinding protein
HCFEABLD_01927 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HCFEABLD_01928 9.4e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HCFEABLD_01929 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HCFEABLD_01930 2.6e-277 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HCFEABLD_01931 3.9e-44 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HCFEABLD_01932 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HCFEABLD_01933 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HCFEABLD_01935 6.5e-142 S haloacid dehalogenase-like hydrolase
HCFEABLD_01936 3e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HCFEABLD_01937 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
HCFEABLD_01938 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
HCFEABLD_01939 1.6e-31 cspA K Cold shock protein domain
HCFEABLD_01940 1.7e-37
HCFEABLD_01941 3.4e-227 sip L Belongs to the 'phage' integrase family
HCFEABLD_01944 2.1e-29
HCFEABLD_01945 1.2e-143 L DNA replication protein
HCFEABLD_01946 9e-267 S Virulence-associated protein E
HCFEABLD_01947 4.5e-85
HCFEABLD_01948 1.5e-23
HCFEABLD_01949 1.1e-51 S head-tail joining protein
HCFEABLD_01950 2.9e-66 L HNH endonuclease
HCFEABLD_01951 3.9e-81 terS L overlaps another CDS with the same product name
HCFEABLD_01952 0.0 terL S overlaps another CDS with the same product name
HCFEABLD_01954 3.7e-199 S Phage portal protein
HCFEABLD_01955 1.3e-208 S Caudovirus prohead serine protease
HCFEABLD_01956 1.7e-41 S Phage gp6-like head-tail connector protein
HCFEABLD_01957 2.1e-53
HCFEABLD_01958 5.1e-49 gepA S Protein of unknown function (DUF4065)
HCFEABLD_01959 7.4e-33
HCFEABLD_01961 6.2e-131 K response regulator
HCFEABLD_01962 0.0 vicK 2.7.13.3 T Histidine kinase
HCFEABLD_01963 1.3e-243 yycH S YycH protein
HCFEABLD_01964 6.5e-151 yycI S YycH protein
HCFEABLD_01965 8.9e-158 vicX 3.1.26.11 S domain protein
HCFEABLD_01966 6.8e-173 htrA 3.4.21.107 O serine protease
HCFEABLD_01967 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCFEABLD_01968 1.5e-95 K Bacterial regulatory proteins, tetR family
HCFEABLD_01969 1.2e-261 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
HCFEABLD_01970 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HCFEABLD_01971 1.8e-92 pnb C nitroreductase
HCFEABLD_01972 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HCFEABLD_01973 1.8e-116 S Elongation factor G-binding protein, N-terminal
HCFEABLD_01974 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
HCFEABLD_01975 1.6e-258 P Sodium:sulfate symporter transmembrane region
HCFEABLD_01976 5.7e-158 K LysR family
HCFEABLD_01977 3e-72 C FMN binding
HCFEABLD_01978 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCFEABLD_01979 2.3e-164 ptlF S KR domain
HCFEABLD_01980 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HCFEABLD_01981 1.3e-122 drgA C Nitroreductase family
HCFEABLD_01982 1e-292 QT PucR C-terminal helix-turn-helix domain
HCFEABLD_01983 5.5e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HCFEABLD_01984 6e-196 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCFEABLD_01985 7.4e-250 yjjP S Putative threonine/serine exporter
HCFEABLD_01986 5.7e-135 wzb 3.1.3.48 T Tyrosine phosphatase family
HCFEABLD_01987 1.4e-254 1.14.14.9 Q 4-hydroxyphenylacetate
HCFEABLD_01988 2.9e-81 6.3.3.2 S ASCH
HCFEABLD_01989 4.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HCFEABLD_01990 2e-169 yobV1 K WYL domain
HCFEABLD_01991 3.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCFEABLD_01992 0.0 tetP J elongation factor G
HCFEABLD_01993 1.9e-29 S Protein of unknown function
HCFEABLD_01994 8.3e-81 S Protein of unknown function
HCFEABLD_01995 5e-154 EG EamA-like transporter family
HCFEABLD_01996 3.6e-93 MA20_25245 K FR47-like protein
HCFEABLD_01997 5.7e-126 hchA S DJ-1/PfpI family
HCFEABLD_01998 1.6e-185 1.1.1.1 C nadph quinone reductase
HCFEABLD_01999 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCFEABLD_02000 2.3e-235 mepA V MATE efflux family protein
HCFEABLD_02001 3e-167 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HCFEABLD_02002 1e-139 S Belongs to the UPF0246 family
HCFEABLD_02003 6e-76
HCFEABLD_02004 1e-309 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
HCFEABLD_02005 1.2e-140
HCFEABLD_02007 7.2e-141 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HCFEABLD_02008 4.8e-40
HCFEABLD_02009 3.9e-128 cbiO P ABC transporter
HCFEABLD_02010 2.6e-149 P Cobalt transport protein
HCFEABLD_02011 4.8e-182 nikMN P PDGLE domain
HCFEABLD_02012 4.2e-121 K Crp-like helix-turn-helix domain
HCFEABLD_02013 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
HCFEABLD_02014 5.3e-125 larB S AIR carboxylase
HCFEABLD_02015 1e-131 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HCFEABLD_02016 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HCFEABLD_02017 2.8e-151 larE S NAD synthase
HCFEABLD_02018 7.9e-177 1.6.5.5 C Zinc-binding dehydrogenase
HCFEABLD_02019 8.4e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HCFEABLD_02020 1.1e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HCFEABLD_02021 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HCFEABLD_02022 5.3e-207 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HCFEABLD_02023 1.6e-137 S peptidase C26
HCFEABLD_02024 2.6e-302 L HIRAN domain
HCFEABLD_02025 9.9e-85 F NUDIX domain
HCFEABLD_02026 2.6e-250 yifK E Amino acid permease
HCFEABLD_02027 0.0 L Transposase
HCFEABLD_02028 1e-117
HCFEABLD_02029 2.8e-148 ydjP I Alpha/beta hydrolase family
HCFEABLD_02030 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HCFEABLD_02031 6.4e-157 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCFEABLD_02032 4.8e-48 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCFEABLD_02033 1.6e-99 S CRISPR-associated protein (Cas_Csn2)
HCFEABLD_02034 0.0 pacL1 P P-type ATPase
HCFEABLD_02035 6.4e-142 2.4.2.3 F Phosphorylase superfamily
HCFEABLD_02036 1.6e-28 KT PspC domain
HCFEABLD_02037 3e-110 S NADPH-dependent FMN reductase
HCFEABLD_02038 1.2e-74 papX3 K Transcriptional regulator
HCFEABLD_02039 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
HCFEABLD_02040 1.8e-53 S Protein of unknown function (DUF3021)
HCFEABLD_02041 4.7e-227 mdtG EGP Major facilitator Superfamily
HCFEABLD_02042 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCFEABLD_02043 8.1e-216 yeaN P Transporter, major facilitator family protein
HCFEABLD_02045 4.9e-159 S reductase
HCFEABLD_02046 1.2e-165 1.1.1.65 C Aldo keto reductase
HCFEABLD_02047 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
HCFEABLD_02048 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HCFEABLD_02049 5e-52
HCFEABLD_02050 7.5e-259
HCFEABLD_02051 6.4e-207 C Oxidoreductase
HCFEABLD_02052 6e-149 cbiQ P cobalt transport
HCFEABLD_02053 0.0 ykoD P ABC transporter, ATP-binding protein
HCFEABLD_02054 2.5e-98 S UPF0397 protein
HCFEABLD_02055 1.6e-129 K UbiC transcription regulator-associated domain protein
HCFEABLD_02056 8.3e-54 K Transcriptional regulator PadR-like family
HCFEABLD_02057 1.7e-142
HCFEABLD_02058 1.5e-149
HCFEABLD_02059 9.1e-89
HCFEABLD_02060 4.4e-34 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HCFEABLD_02061 1.6e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HCFEABLD_02062 1.8e-100 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HCFEABLD_02063 6.7e-170 yjjC V ABC transporter
HCFEABLD_02064 1.7e-296 M Exporter of polyketide antibiotics
HCFEABLD_02065 3.4e-115 K Transcriptional regulator
HCFEABLD_02066 4.4e-275 C Electron transfer flavoprotein FAD-binding domain
HCFEABLD_02067 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
HCFEABLD_02069 1.1e-92 K Bacterial regulatory proteins, tetR family
HCFEABLD_02070 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HCFEABLD_02071 1.9e-186 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HCFEABLD_02072 1.9e-101 dhaL 2.7.1.121 S Dak2
HCFEABLD_02073 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
HCFEABLD_02074 2.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HCFEABLD_02075 1e-190 malR K Transcriptional regulator, LacI family
HCFEABLD_02076 2e-180 yvdE K helix_turn _helix lactose operon repressor
HCFEABLD_02077 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HCFEABLD_02078 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
HCFEABLD_02079 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
HCFEABLD_02080 1.4e-161 malD P ABC transporter permease
HCFEABLD_02081 1.8e-150 malA S maltodextrose utilization protein MalA
HCFEABLD_02082 9.1e-261 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
HCFEABLD_02083 4e-209 msmK P Belongs to the ABC transporter superfamily
HCFEABLD_02084 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HCFEABLD_02085 0.0 3.2.1.96 G Glycosyl hydrolase family 85
HCFEABLD_02086 1.5e-45 ygbF S Sugar efflux transporter for intercellular exchange
HCFEABLD_02087 1e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HCFEABLD_02088 0.0 rafA 3.2.1.22 G alpha-galactosidase
HCFEABLD_02089 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HCFEABLD_02090 3.4e-304 scrB 3.2.1.26 GH32 G invertase
HCFEABLD_02091 9.1e-173 scrR K Transcriptional regulator, LacI family
HCFEABLD_02092 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HCFEABLD_02093 6.5e-165 3.5.1.10 C nadph quinone reductase
HCFEABLD_02094 8.1e-216 nhaC C Na H antiporter NhaC
HCFEABLD_02095 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HCFEABLD_02096 1.8e-133 mleR K LysR substrate binding domain
HCFEABLD_02097 0.0 3.6.4.13 M domain protein
HCFEABLD_02099 2.1e-157 hipB K Helix-turn-helix
HCFEABLD_02100 0.0 oppA E ABC transporter, substratebinding protein
HCFEABLD_02101 1.3e-309 oppA E ABC transporter, substratebinding protein
HCFEABLD_02102 2.6e-79 yiaC K Acetyltransferase (GNAT) domain
HCFEABLD_02103 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCFEABLD_02104 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HCFEABLD_02105 3e-113 pgm1 G phosphoglycerate mutase
HCFEABLD_02106 1.7e-84 yghZ C Aldo keto reductase family protein
HCFEABLD_02107 7.3e-87 yghZ C Aldo keto reductase family protein
HCFEABLD_02108 4.9e-34
HCFEABLD_02109 4.8e-60 S Domain of unknown function (DU1801)
HCFEABLD_02110 6.4e-162 FbpA K Domain of unknown function (DUF814)
HCFEABLD_02111 1e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCFEABLD_02113 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCFEABLD_02114 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCFEABLD_02115 9.5e-262 S ATPases associated with a variety of cellular activities
HCFEABLD_02116 0.0 L Transposase
HCFEABLD_02117 1.8e-116 P cobalt transport
HCFEABLD_02118 1.4e-259 P ABC transporter
HCFEABLD_02119 3.1e-101 S ABC transporter permease
HCFEABLD_02120 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HCFEABLD_02121 1.4e-158 dkgB S reductase
HCFEABLD_02122 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCFEABLD_02123 1e-69
HCFEABLD_02124 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCFEABLD_02126 2.6e-277 pipD E Dipeptidase
HCFEABLD_02127 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HCFEABLD_02128 0.0 mtlR K Mga helix-turn-helix domain
HCFEABLD_02129 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCFEABLD_02130 2.8e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HCFEABLD_02131 2.1e-73
HCFEABLD_02132 6.2e-57 trxA1 O Belongs to the thioredoxin family
HCFEABLD_02133 1.2e-49
HCFEABLD_02134 1.9e-95
HCFEABLD_02135 2e-62
HCFEABLD_02136 3.9e-81 ndk 2.7.4.6 F Belongs to the NDK family
HCFEABLD_02137 1.9e-253 S Uncharacterized protein conserved in bacteria (DUF2252)
HCFEABLD_02138 3.5e-97 yieF S NADPH-dependent FMN reductase
HCFEABLD_02139 2.7e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HCFEABLD_02140 1.3e-210 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HCFEABLD_02141 2.2e-165 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HCFEABLD_02142 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
HCFEABLD_02143 4.3e-141 pnuC H nicotinamide mononucleotide transporter
HCFEABLD_02144 2.4e-41 S Protein of unknown function (DUF2089)
HCFEABLD_02145 2.2e-42
HCFEABLD_02146 3.5e-129 treR K UTRA
HCFEABLD_02147 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HCFEABLD_02148 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HCFEABLD_02149 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HCFEABLD_02150 7e-144
HCFEABLD_02151 4.9e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HCFEABLD_02152 2.1e-235 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
HCFEABLD_02153 0.0 tagF2 2.7.8.12 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCFEABLD_02154 9.2e-168 S Psort location CytoplasmicMembrane, score
HCFEABLD_02155 5.9e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HCFEABLD_02156 1.6e-70
HCFEABLD_02157 1.8e-72 K Transcriptional regulator
HCFEABLD_02158 4.3e-121 K Bacterial regulatory proteins, tetR family
HCFEABLD_02159 8.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
HCFEABLD_02160 5.5e-118
HCFEABLD_02161 5.2e-42
HCFEABLD_02162 1e-40
HCFEABLD_02163 9.7e-253 ydiC1 EGP Major facilitator Superfamily
HCFEABLD_02164 3.3e-65 K helix_turn_helix, mercury resistance
HCFEABLD_02165 1.2e-123 L PFAM transposase IS116 IS110 IS902 family
HCFEABLD_02166 5.8e-250 T PhoQ Sensor
HCFEABLD_02167 8.3e-128 K Transcriptional regulatory protein, C terminal
HCFEABLD_02168 1.8e-49
HCFEABLD_02169 2.1e-129 yidA K Helix-turn-helix domain, rpiR family
HCFEABLD_02170 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCFEABLD_02171 9.9e-57
HCFEABLD_02172 2.1e-41
HCFEABLD_02173 1.4e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HCFEABLD_02174 2e-258 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HCFEABLD_02175 1.3e-47
HCFEABLD_02176 2.7e-123 2.7.6.5 S RelA SpoT domain protein
HCFEABLD_02177 3.1e-104 K transcriptional regulator
HCFEABLD_02178 0.0 ydgH S MMPL family
HCFEABLD_02179 1.3e-107 tag 3.2.2.20 L glycosylase
HCFEABLD_02180 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HCFEABLD_02181 1.6e-192 yclI V MacB-like periplasmic core domain
HCFEABLD_02182 7.1e-121 yclH V ABC transporter
HCFEABLD_02183 2.5e-114 V CAAX protease self-immunity
HCFEABLD_02184 1.6e-118 S CAAX protease self-immunity
HCFEABLD_02185 1.7e-52 M Lysin motif
HCFEABLD_02186 1.2e-29 lytE M LysM domain protein
HCFEABLD_02187 7.4e-67 gcvH E Glycine cleavage H-protein
HCFEABLD_02188 1.1e-177 sepS16B
HCFEABLD_02189 1.3e-131
HCFEABLD_02190 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HCFEABLD_02191 6.8e-57
HCFEABLD_02192 8.9e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCFEABLD_02193 6.5e-78 elaA S GNAT family
HCFEABLD_02194 1.7e-75 K Transcriptional regulator
HCFEABLD_02195 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
HCFEABLD_02196 3.1e-38
HCFEABLD_02197 7.1e-08 S Motility quorum-sensing regulator, toxin of MqsA
HCFEABLD_02198 1.7e-30
HCFEABLD_02199 5.4e-21 U Preprotein translocase subunit SecB
HCFEABLD_02200 2e-205 potD P ABC transporter
HCFEABLD_02201 1.7e-140 potC P ABC transporter permease
HCFEABLD_02202 2.7e-149 potB P ABC transporter permease
HCFEABLD_02203 3.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCFEABLD_02204 3.8e-96 puuR K Cupin domain
HCFEABLD_02205 1.1e-83 6.3.3.2 S ASCH
HCFEABLD_02206 1e-84 K GNAT family
HCFEABLD_02207 8e-91 K acetyltransferase
HCFEABLD_02208 8.1e-22
HCFEABLD_02209 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HCFEABLD_02210 2e-163 ytrB V ABC transporter
HCFEABLD_02211 4.9e-190
HCFEABLD_02212 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
HCFEABLD_02213 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HCFEABLD_02215 3e-240 xylP1 G MFS/sugar transport protein
HCFEABLD_02216 3e-122 qmcA O prohibitin homologues
HCFEABLD_02217 3e-30
HCFEABLD_02218 1.7e-281 pipD E Dipeptidase
HCFEABLD_02219 3e-40
HCFEABLD_02220 6.8e-96 bioY S BioY family
HCFEABLD_02221 1.4e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCFEABLD_02222 1e-61 S CHY zinc finger
HCFEABLD_02223 8.3e-224 mtnE 2.6.1.83 E Aminotransferase
HCFEABLD_02224 1.1e-217
HCFEABLD_02225 3.5e-154 tagG U Transport permease protein
HCFEABLD_02226 3.9e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HCFEABLD_02227 3.8e-44
HCFEABLD_02228 3.9e-93 K Transcriptional regulator PadR-like family
HCFEABLD_02229 2.1e-258 P Major Facilitator Superfamily
HCFEABLD_02230 2.5e-242 amtB P ammonium transporter
HCFEABLD_02231 5.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HCFEABLD_02232 3.7e-44
HCFEABLD_02233 6.3e-102 zmp1 O Zinc-dependent metalloprotease
HCFEABLD_02234 7.2e-121 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HCFEABLD_02235 5.4e-310 mco Q Multicopper oxidase
HCFEABLD_02236 1.1e-54 ypaA S Protein of unknown function (DUF1304)
HCFEABLD_02237 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
HCFEABLD_02238 4.7e-232 flhF N Uncharacterized conserved protein (DUF2075)
HCFEABLD_02239 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HCFEABLD_02240 9.3e-80
HCFEABLD_02241 1.4e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCFEABLD_02242 1.7e-173 rihC 3.2.2.1 F Nucleoside
HCFEABLD_02243 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCFEABLD_02244 0.0
HCFEABLD_02245 5.9e-79 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
HCFEABLD_02246 6.1e-277 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCFEABLD_02247 9.9e-180 proV E ABC transporter, ATP-binding protein
HCFEABLD_02248 2.6e-255 gshR 1.8.1.7 C Glutathione reductase
HCFEABLD_02249 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCFEABLD_02250 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HCFEABLD_02251 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HCFEABLD_02252 0.0 M domain protein
HCFEABLD_02253 9.7e-32 M dTDP-4-dehydrorhamnose reductase activity
HCFEABLD_02255 9.6e-114 L Transposase and inactivated derivatives, IS30 family
HCFEABLD_02256 1.2e-34
HCFEABLD_02258 7.1e-29
HCFEABLD_02259 1.4e-61
HCFEABLD_02260 6.1e-19 S Barstar (barnase inhibitor)
HCFEABLD_02261 9.6e-120 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HCFEABLD_02262 2e-195 uhpT EGP Major facilitator Superfamily
HCFEABLD_02263 6.9e-147 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
HCFEABLD_02264 3.3e-166 K Transcriptional regulator
HCFEABLD_02265 1.5e-149 S hydrolase
HCFEABLD_02266 1.7e-254 brnQ U Component of the transport system for branched-chain amino acids
HCFEABLD_02267 6.1e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCFEABLD_02271 1.4e-52 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCFEABLD_02272 7.2e-32
HCFEABLD_02273 2.9e-17 plnR
HCFEABLD_02274 7.7e-109
HCFEABLD_02275 5.2e-23 plnK
HCFEABLD_02276 3.5e-24 plnJ
HCFEABLD_02277 2.5e-13
HCFEABLD_02278 8e-113 plnP S CAAX protease self-immunity
HCFEABLD_02280 1.7e-97 2.7.13.3 T GHKL domain
HCFEABLD_02281 1e-131 plnD K LytTr DNA-binding domain
HCFEABLD_02282 4.8e-129 S CAAX protease self-immunity
HCFEABLD_02283 2.4e-22 plnF
HCFEABLD_02284 6.7e-23
HCFEABLD_02285 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HCFEABLD_02286 2.6e-234 mesE M Transport protein ComB
HCFEABLD_02287 1.2e-107 S CAAX protease self-immunity
HCFEABLD_02288 9.7e-118 ypbD S CAAX protease self-immunity
HCFEABLD_02289 6.4e-109 V CAAX protease self-immunity
HCFEABLD_02290 6.7e-114 S CAAX protease self-immunity
HCFEABLD_02291 1.8e-47 higA K Helix-turn-helix XRE-family like proteins
HCFEABLD_02292 0.0 helD 3.6.4.12 L DNA helicase
HCFEABLD_02293 9.5e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HCFEABLD_02294 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCFEABLD_02295 9e-130 K UbiC transcription regulator-associated domain protein
HCFEABLD_02296 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCFEABLD_02297 3.9e-24
HCFEABLD_02298 3.8e-75 S Domain of unknown function (DUF3284)
HCFEABLD_02299 1e-30 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCFEABLD_02300 1.2e-208 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCFEABLD_02301 7.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCFEABLD_02302 1e-162 GK ROK family
HCFEABLD_02303 4.1e-133 K Helix-turn-helix domain, rpiR family
HCFEABLD_02304 2.8e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCFEABLD_02305 8.3e-207
HCFEABLD_02306 3.5e-151 S Psort location Cytoplasmic, score
HCFEABLD_02307 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HCFEABLD_02308 6.8e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HCFEABLD_02309 7e-178
HCFEABLD_02310 2.8e-131 cobB K SIR2 family
HCFEABLD_02311 2e-160 yunF F Protein of unknown function DUF72
HCFEABLD_02312 2.6e-70 mutT 3.6.1.55 F DNA mismatch repair protein MutT
HCFEABLD_02313 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCFEABLD_02314 9.2e-212 bcr1 EGP Major facilitator Superfamily
HCFEABLD_02315 1.5e-146 tatD L hydrolase, TatD family
HCFEABLD_02316 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HCFEABLD_02317 8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCFEABLD_02318 3.2e-37 veg S Biofilm formation stimulator VEG
HCFEABLD_02319 7.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HCFEABLD_02320 5.1e-181 S Prolyl oligopeptidase family
HCFEABLD_02321 1.1e-127 fhuC 3.6.3.35 P ABC transporter
HCFEABLD_02322 9.2e-131 znuB U ABC 3 transport family
HCFEABLD_02324 3.7e-43 ankB S ankyrin repeats
HCFEABLD_02325 2.1e-31
HCFEABLD_02326 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HCFEABLD_02327 1.2e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCFEABLD_02328 1.8e-150 bla1 3.5.2.6 V Beta-lactamase enzyme family
HCFEABLD_02329 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCFEABLD_02330 2e-183 S DUF218 domain
HCFEABLD_02331 2.2e-126
HCFEABLD_02332 3.7e-148 yxeH S hydrolase
HCFEABLD_02333 9e-264 ywfO S HD domain protein
HCFEABLD_02334 3.3e-155 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HCFEABLD_02335 3.8e-78 ywiB S Domain of unknown function (DUF1934)
HCFEABLD_02336 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HCFEABLD_02337 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCFEABLD_02338 4.7e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCFEABLD_02339 3.1e-229 tdcC E amino acid
HCFEABLD_02340 3.7e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HCFEABLD_02341 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HCFEABLD_02342 6.4e-131 S YheO-like PAS domain
HCFEABLD_02343 2.5e-26
HCFEABLD_02344 1e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCFEABLD_02345 3e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HCFEABLD_02346 7.8e-41 rpmE2 J Ribosomal protein L31
HCFEABLD_02347 2.7e-213 J translation release factor activity
HCFEABLD_02348 9.2e-127 srtA 3.4.22.70 M sortase family
HCFEABLD_02349 1.7e-91 lemA S LemA family
HCFEABLD_02350 1e-138 htpX O Belongs to the peptidase M48B family
HCFEABLD_02351 2e-146
HCFEABLD_02352 3.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCFEABLD_02353 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCFEABLD_02354 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCFEABLD_02355 4.9e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCFEABLD_02356 2.3e-63 ndoA L Toxic component of a toxin-antitoxin (TA) module
HCFEABLD_02357 0.0 kup P Transport of potassium into the cell
HCFEABLD_02358 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HCFEABLD_02359 1.7e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HCFEABLD_02360 1.2e-188 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HCFEABLD_02361 2e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HCFEABLD_02362 2.1e-129 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HCFEABLD_02363 5.1e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine
HCFEABLD_02364 9.4e-189 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCFEABLD_02365 4.1e-84 S QueT transporter
HCFEABLD_02366 4.5e-169 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HCFEABLD_02367 2.1e-123 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
HCFEABLD_02368 2.1e-114 S (CBS) domain
HCFEABLD_02369 4.2e-264 S Putative peptidoglycan binding domain
HCFEABLD_02370 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HCFEABLD_02371 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCFEABLD_02372 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCFEABLD_02373 3.3e-289 yabM S Polysaccharide biosynthesis protein
HCFEABLD_02374 2.2e-42 yabO J S4 domain protein
HCFEABLD_02376 2.4e-63 divIC D Septum formation initiator
HCFEABLD_02377 3.1e-74 yabR J RNA binding
HCFEABLD_02378 2.2e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCFEABLD_02379 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HCFEABLD_02380 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCFEABLD_02381 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HCFEABLD_02382 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCFEABLD_02383 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HCFEABLD_02386 1.5e-42 S COG NOG38524 non supervised orthologous group
HCFEABLD_02389 3e-252 dtpT U amino acid peptide transporter
HCFEABLD_02390 2e-151 yjjH S Calcineurin-like phosphoesterase
HCFEABLD_02394 1.9e-27 5.3.3.19 S Cupin 2, conserved barrel domain protein
HCFEABLD_02395 2.5e-53 S Cupin domain
HCFEABLD_02396 4.6e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HCFEABLD_02397 4.7e-194 ybiR P Citrate transporter
HCFEABLD_02398 1.6e-151 pnuC H nicotinamide mononucleotide transporter
HCFEABLD_02399 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCFEABLD_02400 1e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCFEABLD_02401 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
HCFEABLD_02402 4.6e-137 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HCFEABLD_02403 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCFEABLD_02404 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HCFEABLD_02405 0.0 pacL 3.6.3.8 P P-type ATPase
HCFEABLD_02406 8.9e-72
HCFEABLD_02407 0.0 yhgF K Tex-like protein N-terminal domain protein
HCFEABLD_02408 5.2e-83 ydcK S Belongs to the SprT family
HCFEABLD_02409 1.2e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HCFEABLD_02410 1.6e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCFEABLD_02412 6.4e-156 G Peptidase_C39 like family
HCFEABLD_02413 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HCFEABLD_02414 3.4e-133 manY G PTS system
HCFEABLD_02415 3.6e-171 manN G system, mannose fructose sorbose family IID component
HCFEABLD_02416 4.7e-64 S Domain of unknown function (DUF956)
HCFEABLD_02417 0.0 levR K Sigma-54 interaction domain
HCFEABLD_02418 9.5e-71 pts10A 2.7.1.191 G PTS system fructose IIA component
HCFEABLD_02419 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
HCFEABLD_02420 1.3e-176 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCFEABLD_02421 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
HCFEABLD_02422 1.2e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
HCFEABLD_02423 8.3e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCFEABLD_02424 1.8e-136 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HCFEABLD_02425 4.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HCFEABLD_02426 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HCFEABLD_02427 1.7e-177 EG EamA-like transporter family
HCFEABLD_02428 2.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCFEABLD_02429 1.8e-113 zmp2 O Zinc-dependent metalloprotease
HCFEABLD_02430 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
HCFEABLD_02431 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HCFEABLD_02432 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
HCFEABLD_02433 2.1e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HCFEABLD_02434 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCFEABLD_02435 3.7e-205 yacL S domain protein
HCFEABLD_02436 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCFEABLD_02437 6.1e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCFEABLD_02438 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HCFEABLD_02439 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCFEABLD_02440 5.3e-98 yacP S YacP-like NYN domain
HCFEABLD_02441 2.4e-101 sigH K Sigma-70 region 2
HCFEABLD_02442 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HCFEABLD_02443 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCFEABLD_02444 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
HCFEABLD_02445 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
HCFEABLD_02446 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCFEABLD_02447 1.1e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCFEABLD_02448 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCFEABLD_02449 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCFEABLD_02450 9.3e-178 F DNA/RNA non-specific endonuclease
HCFEABLD_02451 9e-39 L nuclease
HCFEABLD_02452 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCFEABLD_02453 2.3e-39 K Helix-turn-helix domain
HCFEABLD_02454 2.1e-108 yvdD 3.2.2.10 S Belongs to the LOG family
HCFEABLD_02455 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCFEABLD_02456 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCFEABLD_02457 6.5e-37 nrdH O Glutaredoxin
HCFEABLD_02458 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
HCFEABLD_02459 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCFEABLD_02460 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCFEABLD_02461 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCFEABLD_02462 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCFEABLD_02463 2.2e-38 yaaL S Protein of unknown function (DUF2508)
HCFEABLD_02464 8.7e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCFEABLD_02465 2.4e-53 yaaQ S Cyclic-di-AMP receptor
HCFEABLD_02466 2.2e-185 holB 2.7.7.7 L DNA polymerase III
HCFEABLD_02467 1e-57 yabA L Involved in initiation control of chromosome replication
HCFEABLD_02468 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCFEABLD_02469 2.8e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
HCFEABLD_02470 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HCFEABLD_02471 1.2e-210 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HCFEABLD_02472 6.5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
HCFEABLD_02473 7.7e-144 phnE1 3.6.1.63 U ABC transporter permease
HCFEABLD_02474 1.5e-136 phnE 3.6.1.63 U Phosphonate ABC transporter permease
HCFEABLD_02475 9.7e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HCFEABLD_02476 5.1e-190 phnD P Phosphonate ABC transporter
HCFEABLD_02477 5.6e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HCFEABLD_02478 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HCFEABLD_02479 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HCFEABLD_02480 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCFEABLD_02481 4.1e-297 uup S ABC transporter, ATP-binding protein
HCFEABLD_02482 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HCFEABLD_02483 1.6e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HCFEABLD_02484 4.6e-109 ydiL S CAAX protease self-immunity
HCFEABLD_02485 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCFEABLD_02486 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCFEABLD_02487 0.0 ydaO E amino acid
HCFEABLD_02488 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
HCFEABLD_02489 4.3e-145 pstS P Phosphate
HCFEABLD_02490 1.7e-114 yvyE 3.4.13.9 S YigZ family
HCFEABLD_02491 1.5e-258 comFA L Helicase C-terminal domain protein
HCFEABLD_02492 4.8e-125 comFC S Competence protein
HCFEABLD_02493 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCFEABLD_02494 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCFEABLD_02495 3.5e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCFEABLD_02496 1.2e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HCFEABLD_02497 1.5e-132 K response regulator
HCFEABLD_02498 9.2e-251 phoR 2.7.13.3 T Histidine kinase
HCFEABLD_02499 1.1e-150 pstS P Phosphate
HCFEABLD_02500 6.8e-162 pstC P probably responsible for the translocation of the substrate across the membrane
HCFEABLD_02501 1.5e-155 pstA P Phosphate transport system permease protein PstA
HCFEABLD_02502 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCFEABLD_02503 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCFEABLD_02504 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
HCFEABLD_02505 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
HCFEABLD_02506 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HCFEABLD_02507 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HCFEABLD_02508 2.3e-164 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCFEABLD_02509 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HCFEABLD_02510 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HCFEABLD_02511 1.9e-124 yliE T Putative diguanylate phosphodiesterase
HCFEABLD_02512 6.7e-270 nox C NADH oxidase
HCFEABLD_02513 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCFEABLD_02514 2e-109 yviA S Protein of unknown function (DUF421)
HCFEABLD_02515 1.1e-61 S Protein of unknown function (DUF3290)
HCFEABLD_02516 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HCFEABLD_02517 3.3e-132 yliE T Putative diguanylate phosphodiesterase
HCFEABLD_02518 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCFEABLD_02519 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HCFEABLD_02520 2.7e-211 norA EGP Major facilitator Superfamily
HCFEABLD_02521 1.2e-117 yfbR S HD containing hydrolase-like enzyme
HCFEABLD_02522 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCFEABLD_02523 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCFEABLD_02524 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCFEABLD_02525 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCFEABLD_02526 7.2e-264 argH 4.3.2.1 E argininosuccinate lyase
HCFEABLD_02527 9.3e-87 S Short repeat of unknown function (DUF308)
HCFEABLD_02528 1.1e-161 rapZ S Displays ATPase and GTPase activities
HCFEABLD_02529 2.9e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HCFEABLD_02530 3.7e-168 whiA K May be required for sporulation
HCFEABLD_02531 5.8e-305 oppA E ABC transporter, substratebinding protein
HCFEABLD_02532 1e-176 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCFEABLD_02533 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCFEABLD_02535 4.2e-245 rpoN K Sigma-54 factor, core binding domain
HCFEABLD_02536 7.3e-189 cggR K Putative sugar-binding domain
HCFEABLD_02537 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCFEABLD_02538 3.1e-223 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HCFEABLD_02539 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCFEABLD_02540 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCFEABLD_02541 1.3e-133
HCFEABLD_02542 6.6e-295 clcA P chloride
HCFEABLD_02543 1.2e-30 secG U Preprotein translocase
HCFEABLD_02544 8.5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
HCFEABLD_02545 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCFEABLD_02546 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HCFEABLD_02547 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
HCFEABLD_02548 1.5e-256 glnP P ABC transporter
HCFEABLD_02549 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCFEABLD_02550 4.6e-105 yxjI
HCFEABLD_02551 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
HCFEABLD_02552 1.6e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCFEABLD_02553 1.2e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HCFEABLD_02554 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HCFEABLD_02555 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
HCFEABLD_02556 1.1e-100 dnaQ 2.7.7.7 L DNA polymerase III
HCFEABLD_02557 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
HCFEABLD_02558 3.9e-162 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HCFEABLD_02559 6.2e-168 murB 1.3.1.98 M Cell wall formation
HCFEABLD_02560 0.0 yjcE P Sodium proton antiporter
HCFEABLD_02561 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
HCFEABLD_02562 2.5e-121 S Protein of unknown function (DUF1361)
HCFEABLD_02563 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCFEABLD_02564 1.6e-129 ybbR S YbbR-like protein
HCFEABLD_02565 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCFEABLD_02566 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCFEABLD_02567 4.5e-123 yliE T EAL domain
HCFEABLD_02568 6.4e-148 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HCFEABLD_02569 3.1e-104 K Bacterial regulatory proteins, tetR family
HCFEABLD_02570 1.6e-207 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HCFEABLD_02571 1.5e-52
HCFEABLD_02572 3e-72
HCFEABLD_02573 6e-132 1.5.1.39 C nitroreductase
HCFEABLD_02574 2.7e-138 EGP Transmembrane secretion effector
HCFEABLD_02575 7.3e-34 G Transmembrane secretion effector
HCFEABLD_02576 7.5e-299 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCFEABLD_02577 1.5e-141
HCFEABLD_02579 1.9e-71 spxA 1.20.4.1 P ArsC family
HCFEABLD_02580 1.5e-33
HCFEABLD_02581 1.2e-88 V VanZ like family
HCFEABLD_02582 1.8e-241 EGP Major facilitator Superfamily
HCFEABLD_02583 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HCFEABLD_02584 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HCFEABLD_02585 1.8e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HCFEABLD_02586 5e-153 licD M LicD family
HCFEABLD_02587 1.3e-82 K Transcriptional regulator
HCFEABLD_02588 1.5e-19
HCFEABLD_02589 1.2e-225 pbuG S permease
HCFEABLD_02590 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCFEABLD_02591 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HCFEABLD_02592 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCFEABLD_02593 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HCFEABLD_02594 2e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCFEABLD_02595 0.0 oatA I Acyltransferase
HCFEABLD_02596 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HCFEABLD_02597 5e-69 O OsmC-like protein
HCFEABLD_02598 2.3e-47
HCFEABLD_02599 1.1e-251 yfnA E Amino Acid
HCFEABLD_02600 9.7e-88
HCFEABLD_02601 9.9e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HCFEABLD_02602 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HCFEABLD_02603 1.8e-19
HCFEABLD_02604 6.3e-105 gmk2 2.7.4.8 F Guanylate kinase
HCFEABLD_02605 1.3e-81 zur P Belongs to the Fur family
HCFEABLD_02606 7.1e-12 3.2.1.14 GH18
HCFEABLD_02607 4.9e-148
HCFEABLD_02609 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HCFEABLD_02610 3e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HCFEABLD_02611 4.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCFEABLD_02612 1.4e-40
HCFEABLD_02614 2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCFEABLD_02615 7.8e-149 glnH ET ABC transporter substrate-binding protein
HCFEABLD_02616 3.5e-109 gluC P ABC transporter permease
HCFEABLD_02617 4e-108 glnP P ABC transporter permease
HCFEABLD_02618 1.1e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCFEABLD_02619 2.1e-154 K CAT RNA binding domain
HCFEABLD_02620 7.9e-258 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HCFEABLD_02621 2.4e-141 G YdjC-like protein
HCFEABLD_02622 2.4e-245 steT E amino acid
HCFEABLD_02623 4.8e-73 mgrA K helix_turn_helix multiple antibiotic resistance protein
HCFEABLD_02624 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
HCFEABLD_02625 2e-71 K MarR family
HCFEABLD_02626 4.9e-210 EGP Major facilitator Superfamily
HCFEABLD_02627 3.8e-85 S membrane transporter protein
HCFEABLD_02628 7.1e-98 K Bacterial regulatory proteins, tetR family
HCFEABLD_02629 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCFEABLD_02630 2.9e-78 3.6.1.55 F NUDIX domain
HCFEABLD_02631 1.3e-48 sugE U Multidrug resistance protein
HCFEABLD_02632 1.2e-26
HCFEABLD_02633 5.5e-129 pgm3 G Phosphoglycerate mutase family
HCFEABLD_02634 4.7e-125 pgm3 G Phosphoglycerate mutase family
HCFEABLD_02635 0.0 yjbQ P TrkA C-terminal domain protein
HCFEABLD_02636 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
HCFEABLD_02637 2.9e-111 dedA S SNARE associated Golgi protein
HCFEABLD_02638 0.0 helD 3.6.4.12 L DNA helicase
HCFEABLD_02639 1.7e-165 fabK 1.3.1.9 S Nitronate monooxygenase
HCFEABLD_02640 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HCFEABLD_02641 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HCFEABLD_02643 5.1e-143 spoVK O ATPase family associated with various cellular activities (AAA)
HCFEABLD_02645 7.6e-46 L Helix-turn-helix domain
HCFEABLD_02646 2e-18 L hmm pf00665
HCFEABLD_02647 6.9e-29 L hmm pf00665
HCFEABLD_02648 5.8e-22 L hmm pf00665
HCFEABLD_02649 1.1e-78
HCFEABLD_02650 6.2e-50
HCFEABLD_02651 1.7e-63 K Helix-turn-helix XRE-family like proteins
HCFEABLD_02652 1.7e-109 XK27_07075 V CAAX protease self-immunity
HCFEABLD_02653 3.8e-57 hxlR K HxlR-like helix-turn-helix
HCFEABLD_02654 7.1e-234 EGP Major facilitator Superfamily
HCFEABLD_02655 4.8e-162 S Cysteine-rich secretory protein family
HCFEABLD_02656 7.4e-38 S MORN repeat
HCFEABLD_02657 0.0 XK27_09800 I Acyltransferase family
HCFEABLD_02658 7.1e-37 S Transglycosylase associated protein
HCFEABLD_02659 2.6e-84
HCFEABLD_02660 7.2e-23
HCFEABLD_02661 8.7e-72 asp S Asp23 family, cell envelope-related function
HCFEABLD_02662 5.3e-72 asp2 S Asp23 family, cell envelope-related function
HCFEABLD_02663 1.3e-145 Q Fumarylacetoacetate (FAA) hydrolase family
HCFEABLD_02664 2.7e-156 yjdB S Domain of unknown function (DUF4767)
HCFEABLD_02665 3.4e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HCFEABLD_02666 1.1e-101 G Glycogen debranching enzyme
HCFEABLD_02667 0.0 pepN 3.4.11.2 E aminopeptidase
HCFEABLD_02668 0.0 N Uncharacterized conserved protein (DUF2075)
HCFEABLD_02669 2.6e-44 S MazG-like family
HCFEABLD_02670 6.1e-91 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
HCFEABLD_02671 7.3e-55 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
HCFEABLD_02672 3.2e-230 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
HCFEABLD_02673 2.1e-156 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
HCFEABLD_02675 3.5e-88 S AAA domain
HCFEABLD_02676 1.3e-139 K sequence-specific DNA binding
HCFEABLD_02677 2.3e-96 K Helix-turn-helix domain
HCFEABLD_02678 9.5e-172 K Transcriptional regulator
HCFEABLD_02679 0.0 1.3.5.4 C FMN_bind
HCFEABLD_02681 6.7e-81 rmaD K Transcriptional regulator
HCFEABLD_02682 2.9e-116 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCFEABLD_02683 1.6e-254 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HCFEABLD_02684 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
HCFEABLD_02685 1.5e-277 pipD E Dipeptidase
HCFEABLD_02686 5e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HCFEABLD_02687 8.5e-41
HCFEABLD_02688 4.1e-32 L leucine-zipper of insertion element IS481
HCFEABLD_02689 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HCFEABLD_02690 2.9e-162 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HCFEABLD_02691 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCFEABLD_02692 4.3e-138 S NADPH-dependent FMN reductase
HCFEABLD_02693 3.3e-178
HCFEABLD_02694 4.3e-220 yibE S overlaps another CDS with the same product name
HCFEABLD_02695 1.3e-126 yibF S overlaps another CDS with the same product name
HCFEABLD_02696 2.6e-103 3.2.2.20 K FR47-like protein
HCFEABLD_02697 5e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HCFEABLD_02698 5.6e-49
HCFEABLD_02699 6.5e-190 nlhH_1 I alpha/beta hydrolase fold
HCFEABLD_02700 2.3e-254 xylP2 G symporter
HCFEABLD_02701 8e-282 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCFEABLD_02702 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HCFEABLD_02703 0.0 asnB 6.3.5.4 E Asparagine synthase
HCFEABLD_02704 7.2e-50 azlD S Branched-chain amino acid transport protein (AzlD)
HCFEABLD_02705 1.3e-120 azlC E branched-chain amino acid
HCFEABLD_02706 4.4e-35 yyaN K MerR HTH family regulatory protein
HCFEABLD_02707 1e-106
HCFEABLD_02708 1.4e-117 S Domain of unknown function (DUF4811)
HCFEABLD_02709 7e-270 lmrB EGP Major facilitator Superfamily
HCFEABLD_02710 1.7e-84 merR K MerR HTH family regulatory protein
HCFEABLD_02711 2.6e-58
HCFEABLD_02712 2e-120 sirR K iron dependent repressor
HCFEABLD_02713 6e-31 cspC K Cold shock protein
HCFEABLD_02714 1.5e-130 thrE S Putative threonine/serine exporter
HCFEABLD_02715 2.2e-76 S Threonine/Serine exporter, ThrE
HCFEABLD_02716 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HCFEABLD_02717 2.3e-119 lssY 3.6.1.27 I phosphatase
HCFEABLD_02718 2e-154 I alpha/beta hydrolase fold
HCFEABLD_02719 8.2e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
HCFEABLD_02720 4.2e-92 K Transcriptional regulator
HCFEABLD_02721 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HCFEABLD_02722 9.7e-264 lysP E amino acid
HCFEABLD_02723 2.5e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HCFEABLD_02724 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HCFEABLD_02725 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCFEABLD_02733 6.9e-78 ctsR K Belongs to the CtsR family
HCFEABLD_02734 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCFEABLD_02735 1.5e-109 K Bacterial regulatory proteins, tetR family
HCFEABLD_02736 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCFEABLD_02737 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCFEABLD_02738 7.8e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HCFEABLD_02739 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCFEABLD_02740 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCFEABLD_02741 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCFEABLD_02742 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HCFEABLD_02743 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCFEABLD_02744 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HCFEABLD_02745 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCFEABLD_02746 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCFEABLD_02747 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCFEABLD_02748 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCFEABLD_02749 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCFEABLD_02750 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCFEABLD_02751 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HCFEABLD_02752 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCFEABLD_02753 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCFEABLD_02754 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCFEABLD_02755 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCFEABLD_02756 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCFEABLD_02757 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCFEABLD_02758 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCFEABLD_02759 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCFEABLD_02760 2.2e-24 rpmD J Ribosomal protein L30
HCFEABLD_02761 6.3e-70 rplO J Binds to the 23S rRNA
HCFEABLD_02762 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCFEABLD_02763 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCFEABLD_02764 3.9e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCFEABLD_02765 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCFEABLD_02766 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCFEABLD_02767 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCFEABLD_02768 2.1e-61 rplQ J Ribosomal protein L17
HCFEABLD_02769 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCFEABLD_02770 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
HCFEABLD_02771 1.4e-86 ynhH S NusG domain II
HCFEABLD_02772 0.0 ndh 1.6.99.3 C NADH dehydrogenase
HCFEABLD_02773 1e-141 cad S FMN_bind
HCFEABLD_02774 1.5e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCFEABLD_02775 6.8e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCFEABLD_02776 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCFEABLD_02777 2.1e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCFEABLD_02778 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCFEABLD_02779 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCFEABLD_02780 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HCFEABLD_02781 2.3e-164 degV S Uncharacterised protein, DegV family COG1307
HCFEABLD_02782 3.3e-184 ywhK S Membrane
HCFEABLD_02783 7.6e-205 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HCFEABLD_02784 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCFEABLD_02785 1.3e-165 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCFEABLD_02786 1.8e-184 aroF 2.5.1.54 E DAHP synthetase I family
HCFEABLD_02787 1.9e-195 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HCFEABLD_02788 1.2e-242 P Sodium:sulfate symporter transmembrane region
HCFEABLD_02789 4.1e-53 yitW S Iron-sulfur cluster assembly protein
HCFEABLD_02790 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
HCFEABLD_02791 4.4e-177 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
HCFEABLD_02792 7.2e-197 K Helix-turn-helix domain
HCFEABLD_02793 1.4e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HCFEABLD_02794 4.5e-132 mntB 3.6.3.35 P ABC transporter
HCFEABLD_02795 4.8e-141 mtsB U ABC 3 transport family
HCFEABLD_02796 1.2e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
HCFEABLD_02797 1.2e-49
HCFEABLD_02798 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HCFEABLD_02799 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
HCFEABLD_02800 2.9e-179 citR K sugar-binding domain protein
HCFEABLD_02801 1.7e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HCFEABLD_02802 5.7e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HCFEABLD_02803 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
HCFEABLD_02804 5.5e-164 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HCFEABLD_02805 4.6e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HCFEABLD_02806 7.5e-144 L PFAM Integrase, catalytic core
HCFEABLD_02807 1.1e-48 K sequence-specific DNA binding
HCFEABLD_02809 2.4e-16 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HCFEABLD_02810 2.6e-183 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HCFEABLD_02811 6.4e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCFEABLD_02812 3.9e-262 frdC 1.3.5.4 C FAD binding domain
HCFEABLD_02813 4.7e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HCFEABLD_02814 1.4e-161 mleR K LysR family transcriptional regulator
HCFEABLD_02815 1.8e-167 mleR K LysR family
HCFEABLD_02816 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HCFEABLD_02817 1.4e-165 mleP S Sodium Bile acid symporter family
HCFEABLD_02818 5.8e-253 yfnA E Amino Acid
HCFEABLD_02819 3e-99 S ECF transporter, substrate-specific component
HCFEABLD_02820 2.2e-24
HCFEABLD_02821 0.0 S Alpha beta
HCFEABLD_02822 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
HCFEABLD_02823 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HCFEABLD_02824 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HCFEABLD_02825 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HCFEABLD_02826 2.4e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
HCFEABLD_02827 2.4e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCFEABLD_02828 2.9e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HCFEABLD_02829 3.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
HCFEABLD_02830 2.6e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
HCFEABLD_02831 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCFEABLD_02832 1e-93 S UPF0316 protein
HCFEABLD_02833 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HCFEABLD_02834 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HCFEABLD_02835 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCFEABLD_02836 2.6e-198 camS S sex pheromone
HCFEABLD_02837 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCFEABLD_02838 2.1e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCFEABLD_02839 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCFEABLD_02840 1e-190 yegS 2.7.1.107 G Lipid kinase
HCFEABLD_02841 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCFEABLD_02842 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
HCFEABLD_02843 0.0 yfgQ P E1-E2 ATPase
HCFEABLD_02844 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCFEABLD_02845 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
HCFEABLD_02846 2.3e-151 gntR K rpiR family
HCFEABLD_02847 9.1e-144 lys M Glycosyl hydrolases family 25
HCFEABLD_02848 1.1e-62 S Domain of unknown function (DUF4828)
HCFEABLD_02849 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
HCFEABLD_02850 2.4e-189 mocA S Oxidoreductase
HCFEABLD_02851 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
HCFEABLD_02853 2.3e-75 T Universal stress protein family
HCFEABLD_02854 1.4e-245 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCFEABLD_02855 1.8e-164 S Alpha/beta hydrolase of unknown function (DUF915)
HCFEABLD_02857 1.3e-73
HCFEABLD_02858 5e-107
HCFEABLD_02859 4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HCFEABLD_02860 6.9e-220 pbpX1 V Beta-lactamase
HCFEABLD_02861 6.8e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCFEABLD_02862 1.3e-157 yihY S Belongs to the UPF0761 family
HCFEABLD_02863 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HCFEABLD_02864 1.1e-203 glf 5.4.99.9 M UDP-galactopyranose mutase
HCFEABLD_02865 2.6e-27 wcoI 2.7.10.1, 2.7.10.2 M biosynthesis protein
HCFEABLD_02866 4.3e-21 D protein tyrosine kinase activity
HCFEABLD_02867 8.8e-23 V Beta-lactamase
HCFEABLD_02868 1.7e-86 cps1D M Domain of unknown function (DUF4422)
HCFEABLD_02869 1.4e-79 cps3A S Glycosyltransferase like family 2
HCFEABLD_02870 1.2e-45 cps M Glycosyl transferase, family 2
HCFEABLD_02871 7.3e-77 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
HCFEABLD_02872 7.7e-88 wzy P EpsG family
HCFEABLD_02873 1.3e-77 1.1.1.133 S Glycosyltransferase like family 2
HCFEABLD_02874 2.3e-177 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HCFEABLD_02875 5.3e-164 cps3D
HCFEABLD_02876 1.6e-111 cps3E
HCFEABLD_02877 7.9e-163 cps3F
HCFEABLD_02878 4.1e-206 cps3H
HCFEABLD_02879 2.3e-201 cps3I G Acyltransferase family
HCFEABLD_02880 1.4e-147 cps1D M Domain of unknown function (DUF4422)
HCFEABLD_02881 6.7e-136 K helix_turn_helix, arabinose operon control protein
HCFEABLD_02882 0.0 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HCFEABLD_02883 9.6e-74 K helix_turn_helix multiple antibiotic resistance protein
HCFEABLD_02884 7e-259 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HCFEABLD_02885 3.2e-121 rfbP M Bacterial sugar transferase
HCFEABLD_02886 3.8e-53
HCFEABLD_02887 7.3e-33 S Protein of unknown function (DUF2922)
HCFEABLD_02888 7e-30
HCFEABLD_02889 6.2e-25
HCFEABLD_02890 1.5e-100 K DNA-templated transcription, initiation
HCFEABLD_02891 3.9e-125
HCFEABLD_02892 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
HCFEABLD_02893 4.1e-106 ygaC J Belongs to the UPF0374 family
HCFEABLD_02894 1.3e-134 cwlO M NlpC/P60 family
HCFEABLD_02895 1e-47 K sequence-specific DNA binding
HCFEABLD_02896 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
HCFEABLD_02897 3.5e-149 pbpX V Beta-lactamase
HCFEABLD_02898 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HCFEABLD_02899 9.3e-188 yueF S AI-2E family transporter
HCFEABLD_02900 1.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HCFEABLD_02901 9.5e-213 gntP EG Gluconate
HCFEABLD_02902 7.9e-293 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HCFEABLD_02903 4.3e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HCFEABLD_02904 8.3e-254 gor 1.8.1.7 C Glutathione reductase
HCFEABLD_02905 2e-307 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HCFEABLD_02906 1.7e-273
HCFEABLD_02907 6.5e-198 M MucBP domain
HCFEABLD_02908 7.1e-161 lysR5 K LysR substrate binding domain
HCFEABLD_02909 5.5e-126 yxaA S membrane transporter protein
HCFEABLD_02910 3.2e-57 ywjH S Protein of unknown function (DUF1634)
HCFEABLD_02911 1.3e-309 oppA E ABC transporter, substratebinding protein
HCFEABLD_02912 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCFEABLD_02913 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCFEABLD_02914 7.8e-202 oppD P Belongs to the ABC transporter superfamily
HCFEABLD_02915 1.8e-181 oppF P Belongs to the ABC transporter superfamily
HCFEABLD_02916 1e-63 K Winged helix DNA-binding domain
HCFEABLD_02917 1.6e-102 L Integrase
HCFEABLD_02918 0.0 clpE O Belongs to the ClpA ClpB family
HCFEABLD_02919 6.5e-30
HCFEABLD_02920 2.7e-39 ptsH G phosphocarrier protein HPR
HCFEABLD_02921 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCFEABLD_02922 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HCFEABLD_02923 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
HCFEABLD_02924 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCFEABLD_02925 1.2e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HCFEABLD_02926 4.1e-228 patA 2.6.1.1 E Aminotransferase
HCFEABLD_02927 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
HCFEABLD_02928 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCFEABLD_02931 1.5e-42 S COG NOG38524 non supervised orthologous group
HCFEABLD_02937 5.1e-08
HCFEABLD_02943 1.4e-90 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
HCFEABLD_02944 1.8e-182 P secondary active sulfate transmembrane transporter activity
HCFEABLD_02945 5.8e-94
HCFEABLD_02946 2e-94 K Acetyltransferase (GNAT) domain
HCFEABLD_02947 1.1e-155 T Calcineurin-like phosphoesterase superfamily domain
HCFEABLD_02949 5.2e-232 mntH P H( )-stimulated, divalent metal cation uptake system
HCFEABLD_02950 7.6e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HCFEABLD_02951 1.7e-254 mmuP E amino acid
HCFEABLD_02952 1.7e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HCFEABLD_02953 9.3e-294 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HCFEABLD_02954 3.1e-122
HCFEABLD_02955 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCFEABLD_02956 1.4e-278 bmr3 EGP Major facilitator Superfamily
HCFEABLD_02957 4.8e-139 N Cell shape-determining protein MreB
HCFEABLD_02958 0.0 S Pfam Methyltransferase
HCFEABLD_02959 6.7e-268 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
HCFEABLD_02960 1.8e-297 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HCFEABLD_02961 4.2e-29
HCFEABLD_02962 2.9e-93 ytqB 2.1.1.176 J Putative rRNA methylase
HCFEABLD_02963 2e-123 3.6.1.27 I Acid phosphatase homologues
HCFEABLD_02964 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCFEABLD_02965 3e-301 ytgP S Polysaccharide biosynthesis protein
HCFEABLD_02966 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCFEABLD_02967 3.7e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCFEABLD_02968 4.9e-273 pepV 3.5.1.18 E dipeptidase PepV
HCFEABLD_02969 4.1e-84 uspA T Belongs to the universal stress protein A family
HCFEABLD_02970 5.2e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
HCFEABLD_02971 1.5e-172 ugpA U Binding-protein-dependent transport system inner membrane component
HCFEABLD_02972 1.1e-150 ugpE G ABC transporter permease
HCFEABLD_02973 6.4e-262 ugpB G Bacterial extracellular solute-binding protein
HCFEABLD_02974 3.2e-95 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCFEABLD_02975 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
HCFEABLD_02976 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCFEABLD_02977 3.9e-179 XK27_06930 V domain protein
HCFEABLD_02979 1.2e-124 V Transport permease protein
HCFEABLD_02980 2.3e-156 V ABC transporter
HCFEABLD_02981 4e-176 K LytTr DNA-binding domain
HCFEABLD_02982 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCFEABLD_02983 1.6e-64 K helix_turn_helix, mercury resistance
HCFEABLD_02984 1e-116 GM NAD(P)H-binding
HCFEABLD_02985 1.8e-157 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HCFEABLD_02986 7.6e-149 S Sucrose-6F-phosphate phosphohydrolase
HCFEABLD_02987 1.7e-108
HCFEABLD_02988 2.9e-224 pltK 2.7.13.3 T GHKL domain
HCFEABLD_02989 1.6e-137 pltR K LytTr DNA-binding domain
HCFEABLD_02990 4.5e-55
HCFEABLD_02991 2.5e-59
HCFEABLD_02992 8.7e-114 S CAAX protease self-immunity
HCFEABLD_02993 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
HCFEABLD_02994 1e-90
HCFEABLD_02995 2.5e-46
HCFEABLD_02996 0.0 uvrA2 L ABC transporter
HCFEABLD_02999 2.1e-57
HCFEABLD_03000 3.5e-10
HCFEABLD_03001 2.1e-180
HCFEABLD_03002 1.9e-89 gtcA S Teichoic acid glycosylation protein
HCFEABLD_03003 3.6e-58 S Protein of unknown function (DUF1516)
HCFEABLD_03004 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HCFEABLD_03005 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HCFEABLD_03006 1.4e-306 S Protein conserved in bacteria
HCFEABLD_03007 3.3e-230 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HCFEABLD_03008 3.3e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
HCFEABLD_03009 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
HCFEABLD_03010 1e-304 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HCFEABLD_03011 0.0 yfbS P Sodium:sulfate symporter transmembrane region
HCFEABLD_03012 2.1e-244 dinF V MatE
HCFEABLD_03013 1.9e-31
HCFEABLD_03016 1.3e-78 elaA S Acetyltransferase (GNAT) domain
HCFEABLD_03017 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HCFEABLD_03018 1.4e-43 inlJ M MucBP domain
HCFEABLD_03019 4.1e-74 M1-798 K Rhodanese Homology Domain
HCFEABLD_03020 1e-20 CO cell redox homeostasis
HCFEABLD_03021 4.4e-137 trxB 1.8.1.9 O Glucose inhibited division protein A
HCFEABLD_03022 5.7e-99 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HCFEABLD_03024 3.3e-44 trxA O Belongs to the thioredoxin family
HCFEABLD_03025 6.1e-164 gor 1.8.1.7 C Pyridine nucleotide-disulphide oxidoreductase
HCFEABLD_03027 1.1e-66 slyA K helix_turn_helix multiple antibiotic resistance protein
HCFEABLD_03028 8.2e-41 osmC O OsmC-like protein
HCFEABLD_03029 2.9e-35 osmC O OsmC-like protein
HCFEABLD_03030 1.7e-193 tra L Transposase and inactivated derivatives, IS30 family
HCFEABLD_03031 1.9e-47 KLT serine threonine protein kinase
HCFEABLD_03032 7.5e-33
HCFEABLD_03033 6.4e-35
HCFEABLD_03034 1.9e-234 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HCFEABLD_03035 1.7e-19
HCFEABLD_03037 4e-135 D Cellulose biosynthesis protein BcsQ
HCFEABLD_03038 1e-98 K Primase C terminal 1 (PriCT-1)
HCFEABLD_03040 2.3e-41 S RelB antitoxin
HCFEABLD_03041 1.8e-68 L Putative transposase of IS4/5 family (DUF4096)
HCFEABLD_03042 5.4e-77 L Transposase DDE domain
HCFEABLD_03043 1.1e-28
HCFEABLD_03044 3.7e-31 S Protein of unknown function (DUF2089)
HCFEABLD_03045 1.4e-136 K Helix-turn-helix domain
HCFEABLD_03046 4.9e-176 L Transposase and inactivated derivatives, IS30 family
HCFEABLD_03047 1.1e-33 L Initiator Replication protein
HCFEABLD_03048 5.4e-36 tnp2PF3 L Transposase DDE domain
HCFEABLD_03049 4.5e-36 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HCFEABLD_03050 0.0 pacL 3.6.3.8 P P-type ATPase
HCFEABLD_03051 4.6e-42
HCFEABLD_03052 3.7e-55 repA S Replication initiator protein A
HCFEABLD_03053 5.5e-185 U Relaxase/Mobilisation nuclease domain
HCFEABLD_03054 6.8e-54 S Bacterial mobilisation protein (MobC)
HCFEABLD_03055 4e-29 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HCFEABLD_03056 9.8e-38 tnp2PF3 L Transposase DDE domain
HCFEABLD_03057 1.7e-36 K sequence-specific DNA binding
HCFEABLD_03058 6.1e-45 S Phage derived protein Gp49-like (DUF891)
HCFEABLD_03059 2e-106 L Integrase
HCFEABLD_03060 1e-117 L Transposase and inactivated derivatives, IS30 family
HCFEABLD_03062 6.4e-125 tnp L DDE domain
HCFEABLD_03063 5.4e-93 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCFEABLD_03064 6.3e-117 K Bacterial regulatory proteins, tetR family
HCFEABLD_03065 7.5e-164 V ABC-type multidrug transport system, permease component
HCFEABLD_03066 4.1e-133 V AAA domain, putative AbiEii toxin, Type IV TA system
HCFEABLD_03067 1.7e-84 dps P Belongs to the Dps family
HCFEABLD_03069 0.0 ybfG M peptidoglycan-binding domain-containing protein
HCFEABLD_03070 1.4e-107 L Phage integrase family
HCFEABLD_03071 1.5e-19
HCFEABLD_03072 8e-43 L the current gene model (or a revised gene model) may contain a frame shift
HCFEABLD_03073 1.8e-56 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCFEABLD_03074 4.8e-303 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HCFEABLD_03075 4.5e-36 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HCFEABLD_03076 6.3e-221 L Transposase
HCFEABLD_03077 1e-54 tnp2PF3 L manually curated
HCFEABLD_03078 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HCFEABLD_03079 6.8e-170 L Transposase and inactivated derivatives, IS30 family
HCFEABLD_03080 2.5e-95 tnpR1 L Resolvase, N terminal domain
HCFEABLD_03081 7.7e-301 K Sigma-54 interaction domain
HCFEABLD_03082 9.6e-42 levA G PTS system fructose IIA component
HCFEABLD_03083 6.6e-79 2.7.1.191 G PTS system sorbose subfamily IIB component
HCFEABLD_03084 1.4e-137 M PTS system sorbose-specific iic component
HCFEABLD_03085 1.4e-134 levD G PTS system mannose/fructose/sorbose family IID component
HCFEABLD_03086 1.7e-38
HCFEABLD_03087 8.1e-08 clcA P chloride
HCFEABLD_03088 1.8e-68 L Putative transposase of IS4/5 family (DUF4096)
HCFEABLD_03089 2e-76 L Transposase DDE domain
HCFEABLD_03090 1.1e-193 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCFEABLD_03091 2e-76 L Transposase DDE domain
HCFEABLD_03092 3.9e-68 L Putative transposase of IS4/5 family (DUF4096)
HCFEABLD_03093 2.1e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCFEABLD_03094 9.5e-107 L Resolvase, N terminal domain
HCFEABLD_03095 1.2e-114 L hmm pf00665
HCFEABLD_03096 1.5e-180 1.17.4.1 F Ribonucleotide reductase, small chain
HCFEABLD_03097 2.1e-171 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
HCFEABLD_03098 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCFEABLD_03099 4.7e-81 nrdI F NrdI Flavodoxin like
HCFEABLD_03100 5.9e-61 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCFEABLD_03101 8.6e-96 tnpR1 L Resolvase, N terminal domain
HCFEABLD_03102 4.8e-57 K helix_turn_helix multiple antibiotic resistance protein
HCFEABLD_03103 0.0 kup P Transport of potassium into the cell
HCFEABLD_03104 5.2e-64 KT Transcriptional regulatory protein, C terminal
HCFEABLD_03105 1.1e-220 L Transposase
HCFEABLD_03106 3.7e-220 EGP Major facilitator Superfamily
HCFEABLD_03107 2.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCFEABLD_03108 5.8e-203 3.3.1.1 H adenosylhomocysteinase activity
HCFEABLD_03109 1.5e-145 L COG3547 Transposase and inactivated derivatives
HCFEABLD_03110 1.6e-28 L Psort location Cytoplasmic, score
HCFEABLD_03111 2.2e-41 L Psort location Cytoplasmic, score
HCFEABLD_03112 4.9e-68 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HCFEABLD_03113 0.0 L MobA MobL family protein
HCFEABLD_03114 2.5e-27
HCFEABLD_03115 1.3e-39
HCFEABLD_03116 5.2e-161 L hmm pf00665
HCFEABLD_03117 2.4e-130 L Helix-turn-helix domain
HCFEABLD_03118 1.7e-82
HCFEABLD_03119 9.6e-43 relB L Addiction module antitoxin, RelB DinJ family
HCFEABLD_03121 3.8e-98 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HCFEABLD_03122 4.6e-11
HCFEABLD_03123 9.2e-175 L Transposase and inactivated derivatives, IS30 family
HCFEABLD_03124 6.8e-189 L PFAM Integrase catalytic region
HCFEABLD_03125 1.6e-99 gbuC E glycine betaine
HCFEABLD_03126 5.3e-113 proW E glycine betaine
HCFEABLD_03127 9.6e-185 gbuA 3.6.1.1, 3.6.3.32 E glycine betaine
HCFEABLD_03128 7.7e-188 L Helix-turn-helix domain
HCFEABLD_03129 9e-29 M Lysin motif
HCFEABLD_03130 6.9e-146 L COG3547 Transposase and inactivated derivatives
HCFEABLD_03131 7.6e-28 clcA P domain protein
HCFEABLD_03133 5.2e-34
HCFEABLD_03134 9.3e-144 soj D AAA domain
HCFEABLD_03135 6.7e-212 P Belongs to the ABC transporter superfamily
HCFEABLD_03136 1.5e-247 G Bacterial extracellular solute-binding protein
HCFEABLD_03137 5e-151 U Binding-protein-dependent transport system inner membrane component
HCFEABLD_03138 1.5e-141 U Binding-protein-dependent transport system inner membrane component
HCFEABLD_03139 1.1e-94 repA S Replication initiator protein A
HCFEABLD_03140 5.5e-29
HCFEABLD_03141 1.8e-41
HCFEABLD_03142 1.9e-27
HCFEABLD_03143 0.0 L MobA MobL family protein
HCFEABLD_03144 3.1e-116
HCFEABLD_03145 1.3e-67
HCFEABLD_03146 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HCFEABLD_03147 2e-32
HCFEABLD_03148 1e-196 L Psort location Cytoplasmic, score
HCFEABLD_03149 1.7e-67 3.1.21.3 V type I restriction modification DNA specificity domain
HCFEABLD_03150 3.9e-306 hsdM 2.1.1.72 V type I restriction-modification system
HCFEABLD_03151 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HCFEABLD_03152 6.6e-24 3.6.4.12 L DNA helicase
HCFEABLD_03153 1.4e-34 L AAA ATPase domain
HCFEABLD_03154 2.7e-103 tnpR L Resolvase, N terminal domain
HCFEABLD_03155 1.5e-194 L Transposase and inactivated derivatives, IS30 family
HCFEABLD_03156 3.7e-301 ybeC E amino acid
HCFEABLD_03157 3.2e-172 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HCFEABLD_03158 4.7e-94 tnpR1 L Resolvase, N terminal domain
HCFEABLD_03160 1.4e-33 ydaT
HCFEABLD_03161 1.5e-111 L Transposase and inactivated derivatives, IS30 family
HCFEABLD_03162 1.7e-81 tnp L DDE domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)