ORF_ID e_value Gene_name EC_number CAZy COGs Description
JKHLMKBD_00001 1.6e-152 mutR K Transcriptional activator, Rgg GadR MutR family
JKHLMKBD_00002 4.6e-42 3.6.1.55 F NUDIX domain
JKHLMKBD_00004 3.7e-122 S An automated process has identified a potential problem with this gene model
JKHLMKBD_00005 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
JKHLMKBD_00006 1.4e-15 liaI KT membrane
JKHLMKBD_00007 3.4e-30 liaI KT membrane
JKHLMKBD_00008 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
JKHLMKBD_00009 0.0 V ABC transporter (permease)
JKHLMKBD_00010 1.9e-133 macB2 V ABC transporter, ATP-binding protein
JKHLMKBD_00011 6.2e-166 T Histidine kinase
JKHLMKBD_00012 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JKHLMKBD_00013 4.6e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JKHLMKBD_00015 1.5e-69 pbuX F xanthine permease
JKHLMKBD_00016 2.1e-118 pbuX F xanthine permease
JKHLMKBD_00017 1.5e-247 norM V Multidrug efflux pump
JKHLMKBD_00018 2.8e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JKHLMKBD_00019 1.5e-234 brnQ E Component of the transport system for branched-chain amino acids
JKHLMKBD_00020 2.9e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
JKHLMKBD_00021 2.8e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
JKHLMKBD_00022 9.6e-26 csbD K CsbD-like
JKHLMKBD_00023 1.5e-245 yfnA E amino acid
JKHLMKBD_00024 1.5e-229 S dextransucrase activity
JKHLMKBD_00025 6.1e-146 S dextransucrase activity
JKHLMKBD_00026 1.6e-21 L Integrase core domain protein
JKHLMKBD_00029 6.9e-136 tcyC2 3.6.3.21 E abc transporter atp-binding protein
JKHLMKBD_00030 3e-114 yxeN P ABC transporter, permease protein
JKHLMKBD_00031 6.1e-107 ytmL P ABC transporter (Permease
JKHLMKBD_00032 2.4e-161 ET ABC transporter substrate-binding protein
JKHLMKBD_00033 1.9e-170 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
JKHLMKBD_00034 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
JKHLMKBD_00035 2.4e-40 S Sugar efflux transporter for intercellular exchange
JKHLMKBD_00036 5.9e-23 P FtsX-like permease family
JKHLMKBD_00037 1.2e-90 V abc transporter atp-binding protein
JKHLMKBD_00038 3.9e-82 K WHG domain
JKHLMKBD_00039 1.1e-59 ydhF S Aldo keto reductase
JKHLMKBD_00040 2.9e-39 ydhF S Aldo keto reductase
JKHLMKBD_00042 2.2e-108 XK27_02070 S nitroreductase
JKHLMKBD_00043 9.5e-150 1.13.11.2 S glyoxalase
JKHLMKBD_00044 4.7e-76 ywnA K Transcriptional regulator
JKHLMKBD_00045 8.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
JKHLMKBD_00046 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JKHLMKBD_00047 1.3e-111 drgA C Nitroreductase
JKHLMKBD_00048 7.2e-72 yoaK S Protein of unknown function (DUF1275)
JKHLMKBD_00049 6.8e-161 yvgN C reductase
JKHLMKBD_00050 5.1e-101 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JKHLMKBD_00051 1.5e-08
JKHLMKBD_00052 3e-139 S Abortive infection C-terminus
JKHLMKBD_00053 0.0 L DEAD-like helicases superfamily
JKHLMKBD_00054 4.1e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
JKHLMKBD_00055 1.6e-282 XK27_07020 S Belongs to the UPF0371 family
JKHLMKBD_00057 4.8e-55 K response regulator
JKHLMKBD_00058 2.1e-71 S Signal peptide protein, YSIRK family
JKHLMKBD_00060 4.5e-61
JKHLMKBD_00061 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JKHLMKBD_00062 7.8e-89
JKHLMKBD_00063 4e-20
JKHLMKBD_00064 1.5e-24 IQ PFAM AMP-dependent synthetase and ligase
JKHLMKBD_00065 2.7e-26 IQ PFAM AMP-dependent synthetase and ligase
JKHLMKBD_00066 1.7e-108 MA20_06410 E LysE type translocator
JKHLMKBD_00067 5.6e-08
JKHLMKBD_00068 2.7e-09
JKHLMKBD_00069 0.0 M family 8
JKHLMKBD_00070 2e-162 hrtB V MacB-like periplasmic core domain
JKHLMKBD_00071 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
JKHLMKBD_00072 1.1e-151 V MatE
JKHLMKBD_00074 3.9e-110 C Fe-S oxidoreductases
JKHLMKBD_00075 5.7e-176 EGP Major Facilitator Superfamily
JKHLMKBD_00076 5.5e-258 I radical SAM domain protein
JKHLMKBD_00078 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JKHLMKBD_00079 1.4e-150 L Integrase core domain protein
JKHLMKBD_00080 1.8e-87 L transposase activity
JKHLMKBD_00082 3.9e-92
JKHLMKBD_00083 0.0 sbcC L ATPase involved in DNA repair
JKHLMKBD_00084 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JKHLMKBD_00085 0.0 lacL 3.2.1.23 G -beta-galactosidase
JKHLMKBD_00086 0.0 lacS G transporter
JKHLMKBD_00087 4.9e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
JKHLMKBD_00088 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JKHLMKBD_00089 4e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
JKHLMKBD_00090 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JKHLMKBD_00091 2.3e-184 galR K Transcriptional regulator
JKHLMKBD_00092 2.7e-08 L Integrase core domain protein
JKHLMKBD_00093 1.2e-25 L transposition
JKHLMKBD_00094 7.8e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
JKHLMKBD_00095 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
JKHLMKBD_00096 5.5e-101 V abc transporter atp-binding protein
JKHLMKBD_00097 4.3e-40 V abc transporter atp-binding protein
JKHLMKBD_00098 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
JKHLMKBD_00099 5.1e-87 L Transposase
JKHLMKBD_00100 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JKHLMKBD_00101 1.3e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
JKHLMKBD_00102 1e-133 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JKHLMKBD_00103 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JKHLMKBD_00106 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JKHLMKBD_00107 5.8e-175 vraS 2.7.13.3 T Histidine kinase
JKHLMKBD_00108 3.7e-120 yvqF KT membrane
JKHLMKBD_00109 2.9e-305 prkC 2.7.11.1 KLT serine threonine protein kinase
JKHLMKBD_00110 2e-132 stp 3.1.3.16 T phosphatase
JKHLMKBD_00111 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JKHLMKBD_00112 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JKHLMKBD_00113 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JKHLMKBD_00114 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
JKHLMKBD_00115 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JKHLMKBD_00116 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JKHLMKBD_00117 6.9e-150 XK27_02985 S overlaps another CDS with the same product name
JKHLMKBD_00118 2.1e-148 supH S overlaps another CDS with the same product name
JKHLMKBD_00119 8.6e-63 yvoA_1 K Transcriptional
JKHLMKBD_00120 9.8e-121 skfE V abc transporter atp-binding protein
JKHLMKBD_00121 5.6e-133 V ATPase activity
JKHLMKBD_00122 7.3e-172 oppF P Belongs to the ABC transporter superfamily
JKHLMKBD_00123 1.2e-202 oppD P Belongs to the ABC transporter superfamily
JKHLMKBD_00124 4.5e-166 amiD P ABC transporter (Permease
JKHLMKBD_00125 5.1e-268 amiC P ABC transporter (Permease
JKHLMKBD_00126 0.0 amiA E ABC transporter, substrate-binding protein, family 5
JKHLMKBD_00127 1.2e-24 oppF P Belongs to the ABC transporter superfamily
JKHLMKBD_00128 3.5e-24 oppF P Belongs to the ABC transporter superfamily
JKHLMKBD_00129 8.9e-40 tatD L Hydrolase, tatd
JKHLMKBD_00130 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
JKHLMKBD_00131 2.1e-85 L Integrase core domain protein
JKHLMKBD_00132 1.1e-23 L transposase activity
JKHLMKBD_00133 8.9e-18 L transposase activity
JKHLMKBD_00134 5.9e-180 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
JKHLMKBD_00135 2.8e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
JKHLMKBD_00136 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JKHLMKBD_00137 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
JKHLMKBD_00138 1.5e-103 yjbK S Adenylate cyclase
JKHLMKBD_00139 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JKHLMKBD_00140 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
JKHLMKBD_00141 2e-58 XK27_04120 S Putative amino acid metabolism
JKHLMKBD_00142 1.1e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JKHLMKBD_00143 1.6e-131 puuD T peptidase C26
JKHLMKBD_00144 5.3e-119 radC E Belongs to the UPF0758 family
JKHLMKBD_00145 1.1e-181
JKHLMKBD_00146 1.1e-98
JKHLMKBD_00147 0.0 rgpF M Rhamnan synthesis protein F
JKHLMKBD_00148 1e-193 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JKHLMKBD_00149 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JKHLMKBD_00150 1.4e-142 rgpC GM Transport permease protein
JKHLMKBD_00151 5.3e-178 rgpB GT2 M Glycosyltransferase, group 2 family protein
JKHLMKBD_00152 1.2e-224 rgpA GT4 M Domain of unknown function (DUF1972)
JKHLMKBD_00153 4.8e-09 L Transposase
JKHLMKBD_00154 9.6e-158 L Helix-turn-helix domain of transposase family ISL3
JKHLMKBD_00155 1.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JKHLMKBD_00156 1.6e-244
JKHLMKBD_00157 8.6e-244 S Glucosyl transferase GtrII
JKHLMKBD_00158 3.1e-167 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
JKHLMKBD_00159 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
JKHLMKBD_00160 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JKHLMKBD_00161 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JKHLMKBD_00162 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JKHLMKBD_00163 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
JKHLMKBD_00164 2.1e-202 arcT 2.6.1.1 E Aminotransferase
JKHLMKBD_00165 9.4e-136 ET ABC transporter
JKHLMKBD_00166 8.3e-143 ET Belongs to the bacterial solute-binding protein 3 family
JKHLMKBD_00167 6.4e-84 mutT 3.6.1.55 F Nudix family
JKHLMKBD_00168 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JKHLMKBD_00170 2.3e-54 V CAAX protease self-immunity
JKHLMKBD_00171 2.4e-33 S CAAX amino terminal protease family protein
JKHLMKBD_00172 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
JKHLMKBD_00173 1.8e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
JKHLMKBD_00174 1.1e-16 XK27_00735
JKHLMKBD_00175 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JKHLMKBD_00177 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JKHLMKBD_00179 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
JKHLMKBD_00180 6.6e-30 ycaO O OsmC-like protein
JKHLMKBD_00182 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
JKHLMKBD_00184 8.2e-114 serB 3.1.3.3 E phosphoserine phosphatase
JKHLMKBD_00185 1.4e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JKHLMKBD_00186 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JKHLMKBD_00187 2.8e-108 3.1.3.18 S IA, variant 1
JKHLMKBD_00188 2.5e-116 lrgB M effector of murein hydrolase
JKHLMKBD_00189 7.7e-56 lrgA S Effector of murein hydrolase LrgA
JKHLMKBD_00191 3.2e-59 arsC 1.20.4.1 P Belongs to the ArsC family
JKHLMKBD_00192 1e-54 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
JKHLMKBD_00193 2.4e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JKHLMKBD_00194 8.7e-104 wecD M Acetyltransferase (GNAT) domain
JKHLMKBD_00195 7.4e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JKHLMKBD_00196 2.5e-98 GK ROK family
JKHLMKBD_00197 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
JKHLMKBD_00198 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
JKHLMKBD_00199 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
JKHLMKBD_00200 2.3e-206 potD P spermidine putrescine ABC transporter
JKHLMKBD_00201 1.1e-133 potC P ABC-type spermidine putrescine transport system, permease component II
JKHLMKBD_00202 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
JKHLMKBD_00203 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
JKHLMKBD_00204 7.8e-171 murB 1.3.1.98 M cell wall formation
JKHLMKBD_00205 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JKHLMKBD_00206 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JKHLMKBD_00207 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
JKHLMKBD_00208 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JKHLMKBD_00209 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
JKHLMKBD_00210 0.0 ydaO E amino acid
JKHLMKBD_00211 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JKHLMKBD_00212 4.1e-37 ylqC L Belongs to the UPF0109 family
JKHLMKBD_00213 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JKHLMKBD_00214 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
JKHLMKBD_00215 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
JKHLMKBD_00216 2.1e-74 S QueT transporter
JKHLMKBD_00217 1.9e-55 L Transposase
JKHLMKBD_00218 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JKHLMKBD_00219 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JKHLMKBD_00220 3.7e-85 ccl S cog cog4708
JKHLMKBD_00221 4.9e-160 rbn E Belongs to the UPF0761 family
JKHLMKBD_00222 7.2e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
JKHLMKBD_00223 3.3e-231 ytoI K transcriptional regulator containing CBS domains
JKHLMKBD_00224 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
JKHLMKBD_00225 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JKHLMKBD_00226 0.0 comEC S Competence protein ComEC
JKHLMKBD_00227 7.5e-97 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
JKHLMKBD_00228 1.1e-140 Z012_04635 K Helix-turn-helix XRE-family like proteins
JKHLMKBD_00230 2.7e-112 C 4Fe-4S single cluster domain
JKHLMKBD_00231 9.1e-83 L Integrase core domain protein
JKHLMKBD_00232 1.8e-56 L transposition
JKHLMKBD_00233 7.4e-23 L Transposase
JKHLMKBD_00234 1.9e-46 L transposase activity
JKHLMKBD_00235 3.2e-42 L Transposase
JKHLMKBD_00236 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JKHLMKBD_00237 8.9e-30
JKHLMKBD_00238 1.1e-12
JKHLMKBD_00239 1.3e-87 S Fusaric acid resistance protein-like
JKHLMKBD_00240 8.5e-63 glnR K Transcriptional regulator
JKHLMKBD_00241 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
JKHLMKBD_00242 2.7e-40 pscB M CHAP domain protein
JKHLMKBD_00243 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JKHLMKBD_00244 2.5e-33 ykzG S Belongs to the UPF0356 family
JKHLMKBD_00245 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
JKHLMKBD_00246 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
JKHLMKBD_00247 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JKHLMKBD_00248 1.8e-114 azlC E AzlC protein
JKHLMKBD_00249 2e-47 azlD E branched-chain amino acid
JKHLMKBD_00250 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JKHLMKBD_00251 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JKHLMKBD_00252 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JKHLMKBD_00253 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JKHLMKBD_00254 1e-93 cvpA S toxin biosynthetic process
JKHLMKBD_00255 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JKHLMKBD_00256 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JKHLMKBD_00262 2.5e-230 mutY L A G-specific adenine glycosylase
JKHLMKBD_00263 9.5e-42 XK27_05745
JKHLMKBD_00264 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
JKHLMKBD_00265 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JKHLMKBD_00266 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JKHLMKBD_00268 3.1e-124 XK27_01040 S Pfam PF06570
JKHLMKBD_00269 2e-169 corA P COG0598 Mg2 and Co2 transporters
JKHLMKBD_00270 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JKHLMKBD_00273 3.5e-59 V 'abc transporter, ATP-binding protein
JKHLMKBD_00274 8e-44 V 'abc transporter, ATP-binding protein
JKHLMKBD_00276 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
JKHLMKBD_00277 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
JKHLMKBD_00278 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JKHLMKBD_00279 3.4e-62 yqhY S protein conserved in bacteria
JKHLMKBD_00280 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JKHLMKBD_00281 7.5e-180 scrR K Transcriptional
JKHLMKBD_00282 4.1e-291 scrB 3.2.1.26 GH32 G invertase
JKHLMKBD_00283 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
JKHLMKBD_00284 1.2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
JKHLMKBD_00285 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
JKHLMKBD_00287 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JKHLMKBD_00288 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JKHLMKBD_00289 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JKHLMKBD_00290 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JKHLMKBD_00291 7.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JKHLMKBD_00292 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JKHLMKBD_00293 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
JKHLMKBD_00294 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
JKHLMKBD_00295 2.9e-18 yebC M Membrane
JKHLMKBD_00296 5.2e-81 yebC M Membrane
JKHLMKBD_00297 3.6e-66 KT response to antibiotic
JKHLMKBD_00298 5.2e-75 XK27_02470 K LytTr DNA-binding domain
JKHLMKBD_00299 2.6e-121 liaI S membrane
JKHLMKBD_00300 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JKHLMKBD_00301 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JKHLMKBD_00302 5.2e-125 S Protein of unknown function (DUF554)
JKHLMKBD_00303 8.1e-134 ecsA_2 V abc transporter atp-binding protein
JKHLMKBD_00304 1.9e-284 XK27_00765
JKHLMKBD_00305 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JKHLMKBD_00306 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JKHLMKBD_00307 8.4e-12 D nuclear chromosome segregation
JKHLMKBD_00308 8.7e-33 yhaI J Protein of unknown function (DUF805)
JKHLMKBD_00309 7.5e-30
JKHLMKBD_00310 7.4e-27
JKHLMKBD_00311 3.7e-46
JKHLMKBD_00312 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JKHLMKBD_00313 4.3e-47 ftsL D cell division protein FtsL
JKHLMKBD_00314 0.0 ftsI 3.4.16.4 M penicillin-binding protein
JKHLMKBD_00315 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JKHLMKBD_00316 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JKHLMKBD_00318 6.7e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JKHLMKBD_00319 2.4e-66 yutD J protein conserved in bacteria
JKHLMKBD_00320 3e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
JKHLMKBD_00321 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
JKHLMKBD_00323 0.0 mdlA V abc transporter atp-binding protein
JKHLMKBD_00324 0.0 mdlB V abc transporter atp-binding protein
JKHLMKBD_00325 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JKHLMKBD_00326 7.3e-237 mesE M Transport protein ComB
JKHLMKBD_00328 6e-236 blpH 2.7.13.3 T protein histidine kinase activity
JKHLMKBD_00329 7.4e-135 agrA KT phosphorelay signal transduction system
JKHLMKBD_00333 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
JKHLMKBD_00340 4.4e-97 blpT
JKHLMKBD_00341 2.9e-28 blpT
JKHLMKBD_00342 3e-47 spiA K sequence-specific DNA binding
JKHLMKBD_00345 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
JKHLMKBD_00346 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
JKHLMKBD_00347 5e-44 V CAAX protease self-immunity
JKHLMKBD_00348 4.6e-140 cppA E CppA N-terminal
JKHLMKBD_00349 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
JKHLMKBD_00350 1.2e-117 ybbL S abc transporter atp-binding protein
JKHLMKBD_00351 1.5e-127 ybbM S transport system, permease component
JKHLMKBD_00352 2.9e-87 D nuclear chromosome segregation
JKHLMKBD_00353 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
JKHLMKBD_00354 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JKHLMKBD_00355 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
JKHLMKBD_00356 0.0 pflB 2.3.1.54 C formate acetyltransferase'
JKHLMKBD_00357 5.4e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JKHLMKBD_00359 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
JKHLMKBD_00360 3e-162 yxeN P ABC transporter (Permease
JKHLMKBD_00361 2.2e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
JKHLMKBD_00362 3.2e-09 S Protein of unknown function (DUF4059)
JKHLMKBD_00363 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JKHLMKBD_00364 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
JKHLMKBD_00365 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JKHLMKBD_00366 2.2e-196 ylbL T Belongs to the peptidase S16 family
JKHLMKBD_00367 1.3e-184 yhcC S radical SAM protein
JKHLMKBD_00368 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
JKHLMKBD_00370 0.0 yjcE P NhaP-type Na H and K H antiporters
JKHLMKBD_00371 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
JKHLMKBD_00372 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
JKHLMKBD_00373 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JKHLMKBD_00376 2.4e-75 XK27_03180 T universal stress protein
JKHLMKBD_00377 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
JKHLMKBD_00378 1.7e-137 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JKHLMKBD_00379 6.8e-101 pncA Q isochorismatase
JKHLMKBD_00380 3.7e-154 hlpA M Belongs to the NlpA lipoprotein family
JKHLMKBD_00381 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JKHLMKBD_00382 2.5e-76 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JKHLMKBD_00383 8.3e-151 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JKHLMKBD_00384 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JKHLMKBD_00385 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JKHLMKBD_00386 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JKHLMKBD_00387 3.6e-51
JKHLMKBD_00388 3.7e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JKHLMKBD_00389 1.8e-98 yqeG S hydrolase of the HAD superfamily
JKHLMKBD_00390 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
JKHLMKBD_00391 3.5e-49 yhbY J RNA-binding protein
JKHLMKBD_00392 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JKHLMKBD_00393 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
JKHLMKBD_00394 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JKHLMKBD_00395 2e-140 yqeM Q Methyltransferase domain protein
JKHLMKBD_00396 5e-204 ylbM S Belongs to the UPF0348 family
JKHLMKBD_00397 0.0 2.1.1.72 V type I restriction-modification system
JKHLMKBD_00398 1.7e-105 ywgA 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
JKHLMKBD_00400 3.2e-159 K SIR2-like domain
JKHLMKBD_00401 0.0 hsdR 3.1.21.3 L COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
JKHLMKBD_00402 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
JKHLMKBD_00403 4.3e-24 L Transposase
JKHLMKBD_00404 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JKHLMKBD_00405 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
JKHLMKBD_00406 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
JKHLMKBD_00407 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JKHLMKBD_00408 9.8e-50 yajC U protein transport
JKHLMKBD_00409 1.9e-127 yeeN K transcriptional regulatory protein
JKHLMKBD_00410 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
JKHLMKBD_00411 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
JKHLMKBD_00412 1.4e-105 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
JKHLMKBD_00413 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
JKHLMKBD_00414 9.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
JKHLMKBD_00415 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
JKHLMKBD_00416 1.6e-127 adcB P ABC transporter (Permease
JKHLMKBD_00417 2.2e-136 adcC P ABC transporter, ATP-binding protein
JKHLMKBD_00418 3.1e-72 adcR K transcriptional
JKHLMKBD_00419 1.9e-223 EGP Major facilitator Superfamily
JKHLMKBD_00420 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JKHLMKBD_00421 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JKHLMKBD_00424 9e-170 oppF P Belongs to the ABC transporter superfamily
JKHLMKBD_00425 1.3e-44 oppD P Belongs to the ABC transporter superfamily
JKHLMKBD_00426 4.8e-67 oppD P Belongs to the ABC transporter superfamily
JKHLMKBD_00427 2.5e-32 oppD P Belongs to the ABC transporter superfamily
JKHLMKBD_00428 3e-27 oppD P Belongs to the ABC transporter superfamily
JKHLMKBD_00429 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
JKHLMKBD_00430 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
JKHLMKBD_00431 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
JKHLMKBD_00432 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
JKHLMKBD_00433 4.4e-135 oppA E ABC transporter substrate-binding protein
JKHLMKBD_00434 2.4e-19 oppA E ABC transporter substrate-binding protein
JKHLMKBD_00435 3.5e-274 sufB O assembly protein SufB
JKHLMKBD_00436 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
JKHLMKBD_00437 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JKHLMKBD_00438 1.4e-234 sufD O assembly protein SufD
JKHLMKBD_00439 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
JKHLMKBD_00440 5.1e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
JKHLMKBD_00441 5.7e-135 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
JKHLMKBD_00442 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
JKHLMKBD_00443 5.8e-275 glnP P ABC transporter
JKHLMKBD_00444 1e-123 glnQ E abc transporter atp-binding protein
JKHLMKBD_00447 5e-94 V VanZ like family
JKHLMKBD_00448 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JKHLMKBD_00449 6.5e-202 yhjX P Major Facilitator
JKHLMKBD_00450 3.4e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
JKHLMKBD_00451 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JKHLMKBD_00452 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JKHLMKBD_00453 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JKHLMKBD_00454 2.8e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JKHLMKBD_00455 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JKHLMKBD_00456 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JKHLMKBD_00457 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JKHLMKBD_00458 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JKHLMKBD_00459 2.4e-83 nrdI F Belongs to the NrdI family
JKHLMKBD_00460 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JKHLMKBD_00461 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JKHLMKBD_00462 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
JKHLMKBD_00463 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
JKHLMKBD_00464 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
JKHLMKBD_00465 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JKHLMKBD_00466 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JKHLMKBD_00467 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JKHLMKBD_00468 9.3e-150 ykuT M mechanosensitive ion channel
JKHLMKBD_00469 1.6e-77 sigH K DNA-templated transcription, initiation
JKHLMKBD_00470 1e-84
JKHLMKBD_00471 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
JKHLMKBD_00472 2.8e-52 amd 3.5.1.47 E Peptidase dimerisation domain
JKHLMKBD_00474 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JKHLMKBD_00475 7.9e-39 ptsH G phosphocarrier protein Hpr
JKHLMKBD_00476 2e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
JKHLMKBD_00477 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
JKHLMKBD_00478 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JKHLMKBD_00479 2.2e-34 nrdH O Glutaredoxin
JKHLMKBD_00480 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JKHLMKBD_00481 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JKHLMKBD_00483 1.7e-72 L Transposase (IS116 IS110 IS902 family)
JKHLMKBD_00484 1e-60 L Transposase (IS116 IS110 IS902 family)
JKHLMKBD_00485 1.2e-164 ypuA S secreted protein
JKHLMKBD_00486 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
JKHLMKBD_00487 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
JKHLMKBD_00488 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JKHLMKBD_00489 7e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JKHLMKBD_00490 3.4e-258 noxE P NADH oxidase
JKHLMKBD_00491 1.9e-294 yfmM S abc transporter atp-binding protein
JKHLMKBD_00492 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
JKHLMKBD_00493 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
JKHLMKBD_00494 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
JKHLMKBD_00495 2e-86 S ECF-type riboflavin transporter, S component
JKHLMKBD_00497 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JKHLMKBD_00498 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
JKHLMKBD_00500 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JKHLMKBD_00501 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JKHLMKBD_00502 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JKHLMKBD_00503 0.0 smc D Required for chromosome condensation and partitioning
JKHLMKBD_00504 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JKHLMKBD_00505 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JKHLMKBD_00506 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JKHLMKBD_00507 2.4e-92 pat 2.3.1.183 M acetyltransferase
JKHLMKBD_00508 3e-13
JKHLMKBD_00509 4.1e-22
JKHLMKBD_00510 1.1e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JKHLMKBD_00511 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JKHLMKBD_00512 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
JKHLMKBD_00513 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
JKHLMKBD_00514 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
JKHLMKBD_00515 7.4e-26
JKHLMKBD_00516 7.6e-146 S ABC-2 family transporter protein
JKHLMKBD_00517 1.1e-98 S transport system, permease component
JKHLMKBD_00518 1.3e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JKHLMKBD_00519 6e-186 desK 2.7.13.3 T Histidine kinase
JKHLMKBD_00520 1.5e-132 yvfS V ABC-2 type transporter
JKHLMKBD_00521 1.3e-157 XK27_09825 V abc transporter atp-binding protein
JKHLMKBD_00525 3.3e-212 EGP Major facilitator Superfamily
JKHLMKBD_00526 3.3e-72 hmpT S cog cog4720
JKHLMKBD_00527 1.4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
JKHLMKBD_00528 3.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JKHLMKBD_00529 5.6e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JKHLMKBD_00530 4.9e-297 dnaK O Heat shock 70 kDa protein
JKHLMKBD_00531 1.9e-69 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JKHLMKBD_00532 4.5e-197 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JKHLMKBD_00533 1.3e-102 acmA 3.2.1.17 NU amidase activity
JKHLMKBD_00534 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
JKHLMKBD_00535 2.2e-38 ais G alpha-ribazole phosphatase activity
JKHLMKBD_00536 8.7e-243 XK27_08635 S UPF0210 protein
JKHLMKBD_00537 6.1e-39 gcvR T UPF0237 protein
JKHLMKBD_00538 2.5e-58 capA M Bacterial capsule synthesis protein
JKHLMKBD_00539 4.3e-109 capA M Bacterial capsule synthesis protein
JKHLMKBD_00540 1.3e-41 capA M Bacterial capsule synthesis protein PGA_cap
JKHLMKBD_00541 4.2e-124 tnp L Transposase IS66 family
JKHLMKBD_00542 1.9e-26 isp2 S pathogenesis
JKHLMKBD_00544 1.7e-185
JKHLMKBD_00546 2.5e-40 S Helix-turn-helix domain
JKHLMKBD_00547 4.1e-223 int L Belongs to the 'phage' integrase family
JKHLMKBD_00548 5.9e-91 3.6.4.12 K Divergent AAA domain protein
JKHLMKBD_00549 5.9e-24 3.6.4.12
JKHLMKBD_00550 4.3e-183 EGP Major facilitator Superfamily
JKHLMKBD_00551 2.4e-231 spaC2 V Lanthionine synthetase C family protein
JKHLMKBD_00552 0.0 S Lantibiotic dehydratase, C terminus
JKHLMKBD_00554 1.5e-35 K sequence-specific DNA binding
JKHLMKBD_00555 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
JKHLMKBD_00556 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JKHLMKBD_00557 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JKHLMKBD_00558 1.8e-31 K helix-turn-helix
JKHLMKBD_00559 3.4e-155 degV S DegV family
JKHLMKBD_00560 3.5e-91 yacP S RNA-binding protein containing a PIN domain
JKHLMKBD_00561 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JKHLMKBD_00564 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JKHLMKBD_00565 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JKHLMKBD_00566 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
JKHLMKBD_00567 6.9e-144 S SseB protein N-terminal domain
JKHLMKBD_00568 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
JKHLMKBD_00569 1.2e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JKHLMKBD_00570 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JKHLMKBD_00571 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JKHLMKBD_00572 0.0 clpC O Belongs to the ClpA ClpB family
JKHLMKBD_00573 6.2e-76 ctsR K Belongs to the CtsR family
JKHLMKBD_00574 9.3e-83 S Putative small multi-drug export protein
JKHLMKBD_00575 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JKHLMKBD_00576 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
JKHLMKBD_00578 2e-180 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
JKHLMKBD_00580 7.8e-97 S reductase
JKHLMKBD_00581 2.9e-54 badR K DNA-binding transcription factor activity
JKHLMKBD_00582 5.5e-36 XK27_02060 S Transglycosylase associated protein
JKHLMKBD_00583 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
JKHLMKBD_00584 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JKHLMKBD_00589 1.9e-07
JKHLMKBD_00592 2.6e-10
JKHLMKBD_00597 6.6e-61 EGP Major facilitator Superfamily
JKHLMKBD_00598 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
JKHLMKBD_00599 1.3e-212 pqqE C radical SAM domain protein
JKHLMKBD_00602 2e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JKHLMKBD_00603 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JKHLMKBD_00604 3.9e-19 IQ Acetoin reductase
JKHLMKBD_00605 1.8e-51 IQ Acetoin reductase
JKHLMKBD_00606 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JKHLMKBD_00607 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
JKHLMKBD_00608 4.2e-152 XK27_05470 E Methionine synthase
JKHLMKBD_00609 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JKHLMKBD_00610 2.4e-251 T PhoQ Sensor
JKHLMKBD_00611 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JKHLMKBD_00612 3.6e-154 S TraX protein
JKHLMKBD_00613 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JKHLMKBD_00614 8.3e-159 dprA LU DNA protecting protein DprA
JKHLMKBD_00615 5.3e-167 GK ROK family
JKHLMKBD_00616 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JKHLMKBD_00617 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JKHLMKBD_00618 6.9e-127 K DNA-binding helix-turn-helix protein
JKHLMKBD_00619 1.1e-89 niaR S small molecule binding protein (contains 3H domain)
JKHLMKBD_00620 3.1e-87 niaX
JKHLMKBD_00621 4.7e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JKHLMKBD_00622 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JKHLMKBD_00623 2e-126 gntR1 K transcriptional
JKHLMKBD_00624 6.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JKHLMKBD_00625 9.3e-20 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
JKHLMKBD_00626 2.8e-26 adhP 1.1.1.1 C alcohol dehydrogenase
JKHLMKBD_00627 3.5e-49 adhP 1.1.1.1 C alcohol dehydrogenase
JKHLMKBD_00628 2.4e-59 adhP 1.1.1.1 C alcohol dehydrogenase
JKHLMKBD_00629 9.2e-26
JKHLMKBD_00630 2.1e-07
JKHLMKBD_00631 1.3e-143 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JKHLMKBD_00632 4.2e-158 aatB ET ABC transporter substrate-binding protein
JKHLMKBD_00633 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
JKHLMKBD_00634 4e-105 artQ P ABC transporter (Permease
JKHLMKBD_00635 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
JKHLMKBD_00636 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JKHLMKBD_00637 1.3e-165 cpsY K Transcriptional regulator
JKHLMKBD_00638 3.2e-35 L transposase activity
JKHLMKBD_00639 7.4e-116 mur1 NU muramidase
JKHLMKBD_00640 1.2e-172 yeiH S Membrane
JKHLMKBD_00641 1.7e-08
JKHLMKBD_00642 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
JKHLMKBD_00643 1.3e-88 XK27_10720 D peptidase activity
JKHLMKBD_00644 1.2e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
JKHLMKBD_00645 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
JKHLMKBD_00646 3.7e-157 glcU U Glucose uptake
JKHLMKBD_00647 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
JKHLMKBD_00648 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
JKHLMKBD_00649 1.1e-222 L Transposase
JKHLMKBD_00650 1.5e-59 cysE 2.3.1.30 E serine acetyltransferase
JKHLMKBD_00651 2.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JKHLMKBD_00652 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JKHLMKBD_00653 2.9e-190 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
JKHLMKBD_00654 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
JKHLMKBD_00655 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JKHLMKBD_00656 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
JKHLMKBD_00657 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
JKHLMKBD_00658 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JKHLMKBD_00660 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JKHLMKBD_00662 1.2e-61 KT phosphorelay signal transduction system
JKHLMKBD_00663 7e-34 S Protein of unknown function (DUF3021)
JKHLMKBD_00664 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JKHLMKBD_00665 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
JKHLMKBD_00666 8.2e-70 argR K Regulates arginine biosynthesis genes
JKHLMKBD_00668 1.6e-18 L Belongs to the 'phage' integrase family
JKHLMKBD_00669 1.4e-66 S tRNA_anti-like
JKHLMKBD_00670 1.1e-80
JKHLMKBD_00671 2e-13
JKHLMKBD_00673 1.1e-65 S Virulence-associated protein E
JKHLMKBD_00674 1.8e-124 KL Phage plasmid primase P4 family
JKHLMKBD_00675 2e-21
JKHLMKBD_00676 1.2e-14
JKHLMKBD_00680 1.2e-20 K TRANSCRIPTIONal
JKHLMKBD_00681 4.5e-15 K Cro/C1-type HTH DNA-binding domain
JKHLMKBD_00682 2e-211 sip L Belongs to the 'phage' integrase family
JKHLMKBD_00683 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
JKHLMKBD_00684 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JKHLMKBD_00685 1.2e-24
JKHLMKBD_00686 9.2e-141 1.1.1.169 H Ketopantoate reductase
JKHLMKBD_00687 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JKHLMKBD_00688 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JKHLMKBD_00689 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
JKHLMKBD_00690 2.3e-161 S CHAP domain
JKHLMKBD_00691 2e-32 L Integrase core domain protein
JKHLMKBD_00692 3.5e-50 L transposition
JKHLMKBD_00693 1e-90 L transposase activity
JKHLMKBD_00694 2.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
JKHLMKBD_00695 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JKHLMKBD_00696 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JKHLMKBD_00697 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JKHLMKBD_00698 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JKHLMKBD_00699 9.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
JKHLMKBD_00700 9.3e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKHLMKBD_00701 9.6e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JKHLMKBD_00702 7e-144 recO L Involved in DNA repair and RecF pathway recombination
JKHLMKBD_00703 2.9e-218 araT 2.6.1.1 E Aminotransferase
JKHLMKBD_00704 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JKHLMKBD_00705 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
JKHLMKBD_00706 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JKHLMKBD_00707 5.5e-139 mreC M Involved in formation and maintenance of cell shape
JKHLMKBD_00713 5.3e-11
JKHLMKBD_00723 4.1e-156 V AAA domain, putative AbiEii toxin, Type IV TA system
JKHLMKBD_00724 8.9e-56 V ABC-2 type transporter
JKHLMKBD_00725 2.8e-97
JKHLMKBD_00726 1.1e-23
JKHLMKBD_00727 1.7e-142 plsC 2.3.1.51 I Acyltransferase
JKHLMKBD_00728 5.9e-23 nodB3 G polysaccharide deacetylase
JKHLMKBD_00729 1.3e-38 nodB3 G Polysaccharide deacetylase
JKHLMKBD_00730 4.1e-22 nodB3 G polysaccharide deacetylase
JKHLMKBD_00731 3e-139 yabB 2.1.1.223 L Methyltransferase
JKHLMKBD_00732 1e-41 yazA L endonuclease containing a URI domain
JKHLMKBD_00733 2.4e-239 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JKHLMKBD_00734 6.7e-154 corA P CorA-like protein
JKHLMKBD_00735 1.9e-62 yjqA S Bacterial PH domain
JKHLMKBD_00736 2.1e-97 thiT S Thiamine transporter
JKHLMKBD_00737 3.6e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JKHLMKBD_00738 1.6e-172 yjbB G Permeases of the major facilitator superfamily
JKHLMKBD_00739 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JKHLMKBD_00740 9.3e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
JKHLMKBD_00741 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JKHLMKBD_00745 1.1e-155 cjaA ET ABC transporter substrate-binding protein
JKHLMKBD_00746 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
JKHLMKBD_00747 2.5e-113 P ABC transporter (Permease
JKHLMKBD_00748 6.6e-114 papP P ABC transporter (Permease
JKHLMKBD_00749 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JKHLMKBD_00750 2e-29 copZ 2.7.7.77 P Heavy metal-associated domain protein
JKHLMKBD_00751 0.0 copA 3.6.3.54 P P-type ATPase
JKHLMKBD_00752 2.7e-73 copY K Copper transport repressor, CopY TcrY family
JKHLMKBD_00753 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
JKHLMKBD_00754 2.9e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JKHLMKBD_00755 1.4e-101 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
JKHLMKBD_00756 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
JKHLMKBD_00757 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JKHLMKBD_00758 1.2e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
JKHLMKBD_00759 7.4e-258 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JKHLMKBD_00760 2.6e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
JKHLMKBD_00761 0.0 ctpE P E1-E2 ATPase
JKHLMKBD_00762 3.9e-26
JKHLMKBD_00763 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JKHLMKBD_00764 9.7e-28 L transposase activity
JKHLMKBD_00765 2.7e-129 K transcriptional regulator, MerR family
JKHLMKBD_00766 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
JKHLMKBD_00767 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
JKHLMKBD_00768 1.6e-63 XK27_02560 S cog cog2151
JKHLMKBD_00769 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JKHLMKBD_00770 7.7e-227 ytfP S Flavoprotein
JKHLMKBD_00772 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JKHLMKBD_00773 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
JKHLMKBD_00774 5.1e-182 ecsB U ABC transporter
JKHLMKBD_00775 2.3e-133 ecsA V abc transporter atp-binding protein
JKHLMKBD_00776 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
JKHLMKBD_00777 2.3e-10
JKHLMKBD_00778 1.3e-56 S CD20-like family
JKHLMKBD_00779 3.2e-110
JKHLMKBD_00780 3.6e-88 T PhoQ Sensor
JKHLMKBD_00781 2.2e-43 T PhoQ Sensor
JKHLMKBD_00782 1.8e-39 T PhoQ Sensor
JKHLMKBD_00783 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JKHLMKBD_00784 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
JKHLMKBD_00785 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
JKHLMKBD_00786 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JKHLMKBD_00787 1.7e-94 panT S ECF transporter, substrate-specific component
JKHLMKBD_00788 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
JKHLMKBD_00789 7.3e-166 metF 1.5.1.20 C reductase
JKHLMKBD_00790 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JKHLMKBD_00792 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
JKHLMKBD_00793 0.0 3.6.3.8 P cation transport ATPase
JKHLMKBD_00794 7.7e-19 L transposase activity
JKHLMKBD_00795 6.5e-54 L transposition
JKHLMKBD_00796 9.6e-32 L transposition
JKHLMKBD_00797 9.8e-32 L Integrase core domain protein
JKHLMKBD_00798 3.5e-238 L Transposase
JKHLMKBD_00799 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JKHLMKBD_00800 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JKHLMKBD_00801 3.9e-237 dltB M Membrane protein involved in D-alanine export
JKHLMKBD_00802 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JKHLMKBD_00803 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
JKHLMKBD_00804 0.0 XK27_10035 V abc transporter atp-binding protein
JKHLMKBD_00805 0.0 yfiB1 V abc transporter atp-binding protein
JKHLMKBD_00806 6.6e-105 pvaA M lytic transglycosylase activity
JKHLMKBD_00807 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
JKHLMKBD_00808 4.9e-34 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JKHLMKBD_00809 2.1e-30 rpsT J rRNA binding
JKHLMKBD_00810 9.4e-172 coaA 2.7.1.33 F Pantothenic acid kinase
JKHLMKBD_00811 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
JKHLMKBD_00812 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
JKHLMKBD_00813 7.6e-61 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
JKHLMKBD_00814 2.3e-43 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
JKHLMKBD_00815 1.1e-38 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JKHLMKBD_00816 2.2e-47 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
JKHLMKBD_00817 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
JKHLMKBD_00818 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
JKHLMKBD_00819 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
JKHLMKBD_00820 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
JKHLMKBD_00821 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
JKHLMKBD_00822 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JKHLMKBD_00823 3.1e-81 ypmB S Protein conserved in bacteria
JKHLMKBD_00824 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
JKHLMKBD_00825 4.9e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
JKHLMKBD_00826 1.5e-07
JKHLMKBD_00827 2.4e-30
JKHLMKBD_00828 3e-13
JKHLMKBD_00829 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
JKHLMKBD_00830 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JKHLMKBD_00831 1.1e-80 queD 4.1.2.50, 4.2.3.12 H synthase
JKHLMKBD_00832 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
JKHLMKBD_00833 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
JKHLMKBD_00834 2.2e-19 D nuclear chromosome segregation
JKHLMKBD_00835 4.8e-137 yejC S cyclic nucleotide-binding protein
JKHLMKBD_00836 1.2e-163 rapZ S Displays ATPase and GTPase activities
JKHLMKBD_00837 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JKHLMKBD_00838 8.7e-162 whiA K May be required for sporulation
JKHLMKBD_00839 6.4e-168 pepD E Dipeptidase
JKHLMKBD_00840 5.4e-32 cspD K Cold shock protein domain
JKHLMKBD_00841 8e-42 K Cold-Shock Protein
JKHLMKBD_00842 1.1e-31 L Transposase
JKHLMKBD_00843 1.5e-39 dps P Belongs to the Dps family
JKHLMKBD_00844 1.1e-80 perR P Belongs to the Fur family
JKHLMKBD_00845 8.4e-28 yqgQ S protein conserved in bacteria
JKHLMKBD_00846 2.2e-179 glk 2.7.1.2 G Glucokinase
JKHLMKBD_00847 0.0 typA T GTP-binding protein TypA
JKHLMKBD_00849 1.3e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JKHLMKBD_00850 1.3e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JKHLMKBD_00851 8.2e-170 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JKHLMKBD_00852 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JKHLMKBD_00853 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JKHLMKBD_00854 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JKHLMKBD_00855 1.4e-96 sepF D cell septum assembly
JKHLMKBD_00856 2e-34 yggT D integral membrane protein
JKHLMKBD_00857 6.1e-143 ylmH T S4 RNA-binding domain
JKHLMKBD_00858 1.8e-135 divIVA D Cell division protein DivIVA
JKHLMKBD_00859 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JKHLMKBD_00860 5.5e-30
JKHLMKBD_00861 8.4e-10
JKHLMKBD_00862 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
JKHLMKBD_00863 2e-45 rpmE2 J 50S ribosomal protein L31
JKHLMKBD_00864 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
JKHLMKBD_00865 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
JKHLMKBD_00866 8.9e-155 gst O Glutathione S-transferase
JKHLMKBD_00867 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JKHLMKBD_00868 2.4e-112 tdk 2.7.1.21 F thymidine kinase
JKHLMKBD_00869 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JKHLMKBD_00870 6.8e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JKHLMKBD_00871 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JKHLMKBD_00872 1.4e-36 L transposition
JKHLMKBD_00873 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JKHLMKBD_00874 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JKHLMKBD_00875 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
JKHLMKBD_00876 3.2e-62 fnt P Formate nitrite transporter
JKHLMKBD_00877 9.8e-140 XK27_09615 C reductase
JKHLMKBD_00878 9e-62 XK27_09615 C reductase
JKHLMKBD_00879 4.3e-77 XK27_09620 S reductase
JKHLMKBD_00880 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
JKHLMKBD_00881 5.4e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
JKHLMKBD_00882 6.5e-221 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JKHLMKBD_00883 1.8e-11 WQ51_05710 S Mitochondrial biogenesis AIM24
JKHLMKBD_00884 1.4e-36 WQ51_05710 S Mitochondrial biogenesis AIM24
JKHLMKBD_00885 6.6e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
JKHLMKBD_00886 9.2e-51 S Protein of unknown function (DUF3397)
JKHLMKBD_00887 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JKHLMKBD_00888 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JKHLMKBD_00889 7.3e-69 amiA E transmembrane transport
JKHLMKBD_00890 3e-63 amiA E transmembrane transport
JKHLMKBD_00891 2e-20 amiA E ABC transporter, substrate-binding protein, family 5
JKHLMKBD_00892 1.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JKHLMKBD_00893 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JKHLMKBD_00894 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
JKHLMKBD_00895 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JKHLMKBD_00896 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JKHLMKBD_00897 2e-186 jag S RNA-binding protein
JKHLMKBD_00898 1e-13 rpmH J Ribosomal protein L34
JKHLMKBD_00899 1e-33 L Transposase
JKHLMKBD_00900 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JKHLMKBD_00901 3.1e-08 L PFAM Integrase, catalytic core
JKHLMKBD_00902 0.0 mdlB V abc transporter atp-binding protein
JKHLMKBD_00903 0.0 lmrA V abc transporter atp-binding protein
JKHLMKBD_00904 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JKHLMKBD_00905 2.6e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JKHLMKBD_00906 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
JKHLMKBD_00907 2.5e-132 rr02 KT response regulator
JKHLMKBD_00908 1.6e-218 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JKHLMKBD_00909 2.8e-168 V ABC transporter
JKHLMKBD_00910 5.4e-122 sagI S ABC-2 type transporter
JKHLMKBD_00911 1e-195 yceA S Belongs to the UPF0176 family
JKHLMKBD_00912 3e-27 XK27_00085 K Transcriptional
JKHLMKBD_00913 1.1e-22
JKHLMKBD_00914 2e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
JKHLMKBD_00915 2.5e-113 S VIT family
JKHLMKBD_00916 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JKHLMKBD_00917 4.5e-216 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
JKHLMKBD_00918 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
JKHLMKBD_00919 1.6e-47 ald 1.4.1.1 C Belongs to the AlaDH PNT family
JKHLMKBD_00920 5.7e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JKHLMKBD_00921 4.3e-103 GBS0088 J protein conserved in bacteria
JKHLMKBD_00922 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
JKHLMKBD_00923 1.8e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
JKHLMKBD_00924 5e-179 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
JKHLMKBD_00925 2.6e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JKHLMKBD_00926 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JKHLMKBD_00927 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
JKHLMKBD_00928 2.5e-21
JKHLMKBD_00929 1.3e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JKHLMKBD_00931 3.5e-07 U protein secretion
JKHLMKBD_00932 2.1e-50 U protein secretion
JKHLMKBD_00933 4.9e-12 U protein secretion
JKHLMKBD_00934 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
JKHLMKBD_00935 2.3e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
JKHLMKBD_00936 3.5e-49 XK27_13030
JKHLMKBD_00937 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JKHLMKBD_00938 9.9e-169 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JKHLMKBD_00939 8e-165 S Protein of unknown function (DUF3114)
JKHLMKBD_00940 1.2e-22 S Protein of unknown function (DUF3114)
JKHLMKBD_00941 1.5e-118 yqfA K protein, Hemolysin III
JKHLMKBD_00942 1e-25 K hmm pf08876
JKHLMKBD_00943 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
JKHLMKBD_00944 1.7e-218 mvaS 2.3.3.10 I synthase
JKHLMKBD_00945 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JKHLMKBD_00946 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JKHLMKBD_00947 9.7e-22
JKHLMKBD_00948 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JKHLMKBD_00949 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
JKHLMKBD_00950 1.5e-250 mmuP E amino acid
JKHLMKBD_00951 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
JKHLMKBD_00952 1.4e-29 S Domain of unknown function (DUF1912)
JKHLMKBD_00953 1.1e-14 L Helix-hairpin-helix DNA-binding motif class 1
JKHLMKBD_00954 1.6e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JKHLMKBD_00955 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JKHLMKBD_00956 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JKHLMKBD_00957 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
JKHLMKBD_00958 4.8e-16 S Protein of unknown function (DUF2969)
JKHLMKBD_00961 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
JKHLMKBD_00964 1e-100 S Domain of Unknown Function with PDB structure (DUF3862)
JKHLMKBD_00965 6.1e-70 M Pfam SNARE associated Golgi protein
JKHLMKBD_00966 9.8e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
JKHLMKBD_00967 9.3e-59 S oxidoreductase
JKHLMKBD_00968 8.7e-67 S oxidoreductase
JKHLMKBD_00969 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
JKHLMKBD_00970 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
JKHLMKBD_00971 0.0 clpE O Belongs to the ClpA ClpB family
JKHLMKBD_00972 6.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JKHLMKBD_00973 1.3e-34 ykuJ S protein conserved in bacteria
JKHLMKBD_00974 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
JKHLMKBD_00975 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
JKHLMKBD_00976 1.1e-78 feoA P FeoA domain protein
JKHLMKBD_00977 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
JKHLMKBD_00978 6.6e-08
JKHLMKBD_00979 1.5e-35 yugF I carboxylic ester hydrolase activity
JKHLMKBD_00980 7.5e-23 I Alpha/beta hydrolase family
JKHLMKBD_00981 2.2e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JKHLMKBD_00982 7e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JKHLMKBD_00983 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
JKHLMKBD_00984 6.4e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JKHLMKBD_00986 2.9e-44 licT K transcriptional antiterminator
JKHLMKBD_00987 6.8e-53 licT K transcriptional antiterminator
JKHLMKBD_00988 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JKHLMKBD_00989 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JKHLMKBD_00990 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JKHLMKBD_00991 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JKHLMKBD_00992 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JKHLMKBD_00993 2.5e-220 mdtG EGP Major facilitator Superfamily
JKHLMKBD_00994 2e-33 secG U Preprotein translocase subunit SecG
JKHLMKBD_00995 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JKHLMKBD_00996 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
JKHLMKBD_00997 3.7e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JKHLMKBD_00998 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
JKHLMKBD_00999 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
JKHLMKBD_01000 4.4e-183 ccpA K Catabolite control protein A
JKHLMKBD_01001 6.2e-21 yyaQ S YjbR
JKHLMKBD_01002 3.2e-141 yyaQ S YjbR
JKHLMKBD_01003 3.7e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JKHLMKBD_01004 1e-78 yueI S Protein of unknown function (DUF1694)
JKHLMKBD_01005 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JKHLMKBD_01006 2e-25 WQ51_00785
JKHLMKBD_01007 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JKHLMKBD_01008 2e-219 ywbD 2.1.1.191 J Methyltransferase
JKHLMKBD_01009 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JKHLMKBD_01010 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JKHLMKBD_01011 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JKHLMKBD_01012 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JKHLMKBD_01013 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
JKHLMKBD_01014 3.2e-53 yheA S Belongs to the UPF0342 family
JKHLMKBD_01015 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
JKHLMKBD_01016 1.7e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
JKHLMKBD_01017 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JKHLMKBD_01018 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
JKHLMKBD_01019 1.7e-249 msrR K Transcriptional regulator
JKHLMKBD_01020 4.3e-156 ydiA P C4-dicarboxylate transporter malic acid transport protein
JKHLMKBD_01021 2.4e-203 I acyl-CoA dehydrogenase
JKHLMKBD_01022 4.5e-97 mip S hydroperoxide reductase activity
JKHLMKBD_01023 2.8e-52 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JKHLMKBD_01024 4.4e-183 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JKHLMKBD_01025 4.7e-106
JKHLMKBD_01026 1e-31 K Cro/C1-type HTH DNA-binding domain
JKHLMKBD_01027 3e-49 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
JKHLMKBD_01028 6.3e-33 estA E GDSL-like Lipase/Acylhydrolase
JKHLMKBD_01029 1.1e-94
JKHLMKBD_01030 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
JKHLMKBD_01031 7.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JKHLMKBD_01032 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JKHLMKBD_01033 7.7e-186 S CRISPR-associated protein Csn2 subfamily St
JKHLMKBD_01034 2.4e-147 ycgQ S TIGR03943 family
JKHLMKBD_01035 1.3e-154 XK27_03015 S permease
JKHLMKBD_01037 0.0 yhgF K Transcriptional accessory protein
JKHLMKBD_01038 9.9e-42 pspC KT PspC domain
JKHLMKBD_01039 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JKHLMKBD_01040 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JKHLMKBD_01042 5.5e-69 ytxH S General stress protein
JKHLMKBD_01044 2e-177 yegQ O Peptidase U32
JKHLMKBD_01045 2.9e-251 yegQ O Peptidase U32
JKHLMKBD_01046 8.1e-46 S CHY zinc finger
JKHLMKBD_01047 8.4e-88 bioY S biotin synthase
JKHLMKBD_01049 1.1e-33 XK27_12190 S protein conserved in bacteria
JKHLMKBD_01050 6.6e-235 mntH P H( )-stimulated, divalent metal cation uptake system
JKHLMKBD_01052 1.2e-67 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
JKHLMKBD_01053 0.0 L helicase
JKHLMKBD_01054 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JKHLMKBD_01055 1e-163 M LysM domain
JKHLMKBD_01056 7.6e-16
JKHLMKBD_01057 7.5e-174 S hydrolase
JKHLMKBD_01058 1.9e-115 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
JKHLMKBD_01059 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JKHLMKBD_01060 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
JKHLMKBD_01061 2.7e-27 P Hemerythrin HHE cation binding domain protein
JKHLMKBD_01062 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JKHLMKBD_01063 7.2e-23 MA20_36090 S Protein of unknown function (DUF2974)
JKHLMKBD_01064 1.2e-21 MA20_36090 S Protein of unknown function (DUF2974)
JKHLMKBD_01065 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
JKHLMKBD_01066 3.6e-288 hsdM 2.1.1.72 V N-6 DNA Methylase
JKHLMKBD_01067 1e-88 3.1.21.3 V type I restriction modification DNA specificity domain
JKHLMKBD_01069 1.3e-69
JKHLMKBD_01070 3.3e-170 spd F DNA RNA non-specific endonuclease
JKHLMKBD_01071 1.7e-91 lemA S LemA family
JKHLMKBD_01072 4.6e-131 htpX O Belongs to the peptidase M48B family
JKHLMKBD_01073 4.2e-75 S Psort location CytoplasmicMembrane, score
JKHLMKBD_01074 6.2e-56 S Domain of unknown function (DUF4430)
JKHLMKBD_01075 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JKHLMKBD_01076 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
JKHLMKBD_01077 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
JKHLMKBD_01079 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
JKHLMKBD_01080 2e-09 L thioesterase
JKHLMKBD_01081 2.3e-142 S Macro domain protein
JKHLMKBD_01082 4.8e-51 trxA O Belongs to the thioredoxin family
JKHLMKBD_01083 7.2e-74 yccU S CoA-binding protein
JKHLMKBD_01084 1.6e-143 tatD L Hydrolase, tatd
JKHLMKBD_01085 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JKHLMKBD_01086 5.2e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JKHLMKBD_01088 2.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JKHLMKBD_01089 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JKHLMKBD_01090 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
JKHLMKBD_01091 6.9e-173 rmuC S RmuC domain protein
JKHLMKBD_01092 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
JKHLMKBD_01093 1.1e-142 purR 2.4.2.7 F operon repressor
JKHLMKBD_01094 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JKHLMKBD_01095 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JKHLMKBD_01096 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JKHLMKBD_01097 2.7e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JKHLMKBD_01098 1.7e-111 L Transposase
JKHLMKBD_01099 1e-102 L Transposase
JKHLMKBD_01100 9.8e-163 L Integrase core domain protein
JKHLMKBD_01101 1.1e-82 L Helix-turn-helix domain
JKHLMKBD_01102 1.9e-21 L Helix-turn-helix domain
JKHLMKBD_01103 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
JKHLMKBD_01104 3.1e-268 clcA P Chloride transporter, ClC family
JKHLMKBD_01105 8.9e-206 potD P spermidine putrescine ABC transporter
JKHLMKBD_01106 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
JKHLMKBD_01107 1e-221 L Transposase
JKHLMKBD_01108 1.4e-36 L transposition
JKHLMKBD_01109 1.5e-30 L transposition
JKHLMKBD_01110 6.4e-18 L transposase activity
JKHLMKBD_01111 4.4e-37 L Transposase
JKHLMKBD_01112 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JKHLMKBD_01113 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JKHLMKBD_01114 5.2e-142 cmpC S abc transporter atp-binding protein
JKHLMKBD_01115 0.0 WQ51_06230 S ABC transporter substrate binding protein
JKHLMKBD_01116 6.4e-69 L Transposase
JKHLMKBD_01117 9.7e-301 U relaxase
JKHLMKBD_01118 6.8e-57 S Bacterial mobilisation protein (MobC)
JKHLMKBD_01119 3e-57
JKHLMKBD_01120 3.6e-09
JKHLMKBD_01121 6.5e-84 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
JKHLMKBD_01123 1.1e-60 lptA M Putative Ig domain
JKHLMKBD_01125 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JKHLMKBD_01126 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
JKHLMKBD_01127 1.1e-144 L Transposase
JKHLMKBD_01128 7.1e-89 L Transposase
JKHLMKBD_01129 0.0 copB 3.6.3.4 P P-type ATPase
JKHLMKBD_01130 1.6e-88 L Transposase
JKHLMKBD_01131 1.3e-154 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JKHLMKBD_01133 4.6e-19 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JKHLMKBD_01134 6.4e-108 S Domain of unknown function (DUF1803)
JKHLMKBD_01135 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
JKHLMKBD_01142 2.1e-88 L Transposase
JKHLMKBD_01143 7.8e-102 ygaC J Belongs to the UPF0374 family
JKHLMKBD_01144 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
JKHLMKBD_01145 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JKHLMKBD_01146 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
JKHLMKBD_01147 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
JKHLMKBD_01148 1.9e-115 S Haloacid dehalogenase-like hydrolase
JKHLMKBD_01149 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
JKHLMKBD_01150 4e-72 marR K Transcriptional regulator, MarR family
JKHLMKBD_01151 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JKHLMKBD_01152 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKHLMKBD_01153 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
JKHLMKBD_01154 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
JKHLMKBD_01155 1.6e-126 IQ reductase
JKHLMKBD_01156 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JKHLMKBD_01157 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JKHLMKBD_01158 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JKHLMKBD_01159 4.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
JKHLMKBD_01160 4.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JKHLMKBD_01161 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
JKHLMKBD_01162 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JKHLMKBD_01163 2.1e-57 tnp L Transposase
JKHLMKBD_01164 1.4e-60 S Bacterial PH domain
JKHLMKBD_01168 1.5e-27 S Antidote-toxin recognition MazE, bacterial antitoxin
JKHLMKBD_01169 5.5e-98 L transposition
JKHLMKBD_01170 1.7e-38 L transposase activity
JKHLMKBD_01171 4.1e-26
JKHLMKBD_01172 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
JKHLMKBD_01173 2e-299 hsdM 2.1.1.72 V HsdM N-terminal domain
JKHLMKBD_01174 1.7e-93 3.1.21.3 V Type I restriction modification DNA specificity domain
JKHLMKBD_01175 8.1e-203 rny D Endoribonuclease that initiates mRNA decay
JKHLMKBD_01176 1.8e-84 L Transposase
JKHLMKBD_01177 2.1e-113 fruR K transcriptional
JKHLMKBD_01178 4.6e-163 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
JKHLMKBD_01179 2.1e-78 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
JKHLMKBD_01180 5.1e-156 fruA 2.7.1.202 G phosphotransferase system
JKHLMKBD_01181 5.3e-35 fruA 2.7.1.202 G phosphotransferase system
JKHLMKBD_01182 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JKHLMKBD_01183 2.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JKHLMKBD_01185 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
JKHLMKBD_01186 2.9e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JKHLMKBD_01187 2.2e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
JKHLMKBD_01188 9.4e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
JKHLMKBD_01189 2.9e-26 2.3.1.128 K acetyltransferase
JKHLMKBD_01190 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
JKHLMKBD_01191 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JKHLMKBD_01192 1.4e-130 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JKHLMKBD_01193 2.6e-64 WQ51_03320 S cog cog4835
JKHLMKBD_01194 6.4e-61 XK27_08360 S EDD domain protein, DegV family
JKHLMKBD_01195 5.5e-75 XK27_08360 S EDD domain protein, DegV family
JKHLMKBD_01196 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JKHLMKBD_01197 1.5e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JKHLMKBD_01198 0.0 yfmR S abc transporter atp-binding protein
JKHLMKBD_01199 1.6e-24 U response to pH
JKHLMKBD_01200 3.1e-136 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
JKHLMKBD_01201 1.5e-166 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
JKHLMKBD_01202 6.9e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
JKHLMKBD_01203 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
JKHLMKBD_01204 1.9e-77 K DNA-binding transcription factor activity
JKHLMKBD_01205 0.0 lmrA1 V abc transporter atp-binding protein
JKHLMKBD_01206 0.0 lmrA2 V abc transporter atp-binding protein
JKHLMKBD_01207 2.2e-18 K Acetyltransferase (GNAT) family
JKHLMKBD_01208 3.2e-78 sptS 2.7.13.3 T Histidine kinase
JKHLMKBD_01209 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JKHLMKBD_01210 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JKHLMKBD_01211 5.3e-161 cvfB S Protein conserved in bacteria
JKHLMKBD_01212 7.4e-35 yozE S Belongs to the UPF0346 family
JKHLMKBD_01213 4.1e-121 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
JKHLMKBD_01215 3e-61 rlpA M LysM domain protein
JKHLMKBD_01216 8e-191 phoH T phosphate starvation-inducible protein PhoH
JKHLMKBD_01220 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JKHLMKBD_01221 5.9e-163 K transcriptional regulator (lysR family)
JKHLMKBD_01222 1.4e-181 coiA 3.6.4.12 S Competence protein
JKHLMKBD_01223 0.0 pepF E oligoendopeptidase F
JKHLMKBD_01224 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
JKHLMKBD_01225 1.1e-166 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
JKHLMKBD_01226 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JKHLMKBD_01227 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
JKHLMKBD_01228 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
JKHLMKBD_01229 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
JKHLMKBD_01230 9.5e-86 3.4.17.14, 3.5.1.28 NU amidase activity
JKHLMKBD_01231 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JKHLMKBD_01232 2.2e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
JKHLMKBD_01233 7.7e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JKHLMKBD_01234 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JKHLMKBD_01235 9.3e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
JKHLMKBD_01236 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
JKHLMKBD_01237 4.1e-132 yxkH G deacetylase
JKHLMKBD_01238 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
JKHLMKBD_01239 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JKHLMKBD_01240 5.5e-153 rarD S Transporter
JKHLMKBD_01241 2.2e-15 T peptidase
JKHLMKBD_01242 8.9e-14 coiA 3.6.4.12 S Competence protein
JKHLMKBD_01243 4.1e-112 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JKHLMKBD_01244 8.3e-75 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JKHLMKBD_01245 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JKHLMKBD_01246 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JKHLMKBD_01247 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
JKHLMKBD_01248 3.3e-78 atpF C ATP synthase F(0) sector subunit b
JKHLMKBD_01249 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JKHLMKBD_01250 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JKHLMKBD_01251 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JKHLMKBD_01252 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JKHLMKBD_01253 2e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JKHLMKBD_01254 2.8e-230 ftsW D Belongs to the SEDS family
JKHLMKBD_01255 3.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JKHLMKBD_01256 1.2e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JKHLMKBD_01257 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JKHLMKBD_01258 1.4e-161 holB 2.7.7.7 L dna polymerase iii
JKHLMKBD_01259 3.1e-134 yaaT S stage 0 sporulation protein
JKHLMKBD_01260 9.5e-55 yabA L Involved in initiation control of chromosome replication
JKHLMKBD_01261 1.7e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JKHLMKBD_01262 6.8e-226 amt P Ammonium Transporter
JKHLMKBD_01263 1.8e-51 glnB K Belongs to the P(II) protein family
JKHLMKBD_01264 6e-104 mur1 NU mannosyl-glycoprotein
JKHLMKBD_01265 3.3e-144 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
JKHLMKBD_01266 3e-66 nptA P COG1283 Na phosphate symporter
JKHLMKBD_01267 3.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JKHLMKBD_01268 1.8e-53
JKHLMKBD_01269 7.5e-26
JKHLMKBD_01270 1.5e-59
JKHLMKBD_01271 6.1e-63 S membrane
JKHLMKBD_01272 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JKHLMKBD_01273 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JKHLMKBD_01274 4.5e-39 ynzC S UPF0291 protein
JKHLMKBD_01275 5.6e-253 cycA E permease
JKHLMKBD_01276 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
JKHLMKBD_01277 9.8e-71 pts33BCA G pts system
JKHLMKBD_01278 1.1e-76 pts33BCA G pts system
JKHLMKBD_01279 5.5e-84 pts33BCA G pts system
JKHLMKBD_01280 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JKHLMKBD_01285 1.4e-167 fhuR K transcriptional regulator (lysR family)
JKHLMKBD_01286 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JKHLMKBD_01287 5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JKHLMKBD_01288 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JKHLMKBD_01289 4.9e-227 pyrP F uracil Permease
JKHLMKBD_01290 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JKHLMKBD_01291 4.2e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
JKHLMKBD_01292 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
JKHLMKBD_01293 7.1e-133 2.1.1.223 S Putative SAM-dependent methyltransferase
JKHLMKBD_01294 4.4e-30 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JKHLMKBD_01295 3.6e-35 V efflux transmembrane transporter activity
JKHLMKBD_01296 3.1e-31 V efflux transmembrane transporter activity
JKHLMKBD_01297 8.2e-28 ytrF V efflux transmembrane transporter activity
JKHLMKBD_01298 8.2e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JKHLMKBD_01299 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JKHLMKBD_01300 9.1e-110 L Transposase
JKHLMKBD_01301 3.5e-110 L Transposase
JKHLMKBD_01302 1e-119 L Integrase core domain
JKHLMKBD_01303 5.6e-133 L Transposase and inactivated derivatives
JKHLMKBD_01304 1.1e-44 L COG2963 Transposase and inactivated derivatives
JKHLMKBD_01305 3.2e-92 dps P Belongs to the Dps family
JKHLMKBD_01306 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
JKHLMKBD_01307 9.5e-94 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
JKHLMKBD_01308 3.1e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JKHLMKBD_01309 4.7e-249 L Transposase
JKHLMKBD_01310 6e-88 L Transposase
JKHLMKBD_01311 5.2e-113 L Transposase
JKHLMKBD_01312 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JKHLMKBD_01313 4.4e-123 comFC S Competence protein
JKHLMKBD_01314 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JKHLMKBD_01315 6.3e-111 yvyE 3.4.13.9 S YigZ family
JKHLMKBD_01316 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JKHLMKBD_01317 3.3e-43 acuB S IMP dehydrogenase activity
JKHLMKBD_01318 2.8e-70 acuB S IMP dehydrogenase activity
JKHLMKBD_01319 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
JKHLMKBD_01320 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
JKHLMKBD_01321 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
JKHLMKBD_01322 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
JKHLMKBD_01323 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
JKHLMKBD_01324 7.1e-46 ylbG S UPF0298 protein
JKHLMKBD_01325 1.2e-74 ylbF S Belongs to the UPF0342 family
JKHLMKBD_01326 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JKHLMKBD_01327 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JKHLMKBD_01330 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
JKHLMKBD_01331 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
JKHLMKBD_01332 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
JKHLMKBD_01333 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
JKHLMKBD_01334 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JKHLMKBD_01335 8e-213 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
JKHLMKBD_01337 3.8e-73 yvdD 3.2.2.10 S Belongs to the LOG family
JKHLMKBD_01338 6.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JKHLMKBD_01339 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JKHLMKBD_01340 1.4e-41 ylxQ J ribosomal protein
JKHLMKBD_01341 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
JKHLMKBD_01342 3.1e-212 nusA K Participates in both transcription termination and antitermination
JKHLMKBD_01343 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
JKHLMKBD_01344 2.5e-220 brpA K Transcriptional
JKHLMKBD_01345 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
JKHLMKBD_01346 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
JKHLMKBD_01347 3.3e-248 pbuO S permease
JKHLMKBD_01348 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
JKHLMKBD_01349 1.3e-139 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
JKHLMKBD_01350 6.3e-174 manL 2.7.1.191 G pts system
JKHLMKBD_01351 2.3e-116 manM G pts system
JKHLMKBD_01352 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
JKHLMKBD_01353 4.2e-62 manO S protein conserved in bacteria
JKHLMKBD_01354 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JKHLMKBD_01355 1.2e-40 L transposase activity
JKHLMKBD_01356 5.7e-23 L Transposase
JKHLMKBD_01357 3e-27 L Integrase core domain protein
JKHLMKBD_01358 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
JKHLMKBD_01359 1.2e-34
JKHLMKBD_01361 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JKHLMKBD_01362 5.2e-167 dnaI L Primosomal protein DnaI
JKHLMKBD_01363 6.5e-218 dnaB L Replication initiation and membrane attachment
JKHLMKBD_01364 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JKHLMKBD_01365 2.8e-282 T PhoQ Sensor
JKHLMKBD_01366 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JKHLMKBD_01367 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
JKHLMKBD_01368 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
JKHLMKBD_01369 5.2e-243 P COG0168 Trk-type K transport systems, membrane components
JKHLMKBD_01370 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
JKHLMKBD_01371 9.7e-13 ulaG S L-ascorbate 6-phosphate lactonase
JKHLMKBD_01372 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JKHLMKBD_01373 1.2e-149 cbiQ P cobalt transport
JKHLMKBD_01374 0.0 ykoD P abc transporter atp-binding protein
JKHLMKBD_01375 9.4e-95 S UPF0397 protein
JKHLMKBD_01376 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
JKHLMKBD_01377 4.6e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JKHLMKBD_01378 3e-98 metI P ABC transporter (Permease
JKHLMKBD_01379 1.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JKHLMKBD_01380 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
JKHLMKBD_01381 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
JKHLMKBD_01382 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
JKHLMKBD_01383 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
JKHLMKBD_01384 4e-153 ET amino acid transport
JKHLMKBD_01385 3.8e-205 EGP Transmembrane secretion effector
JKHLMKBD_01386 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
JKHLMKBD_01387 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JKHLMKBD_01388 8e-117 ET amino acid transport
JKHLMKBD_01389 1.8e-21 ET amino acid transport
JKHLMKBD_01390 3.1e-130 cbiO P ABC transporter
JKHLMKBD_01391 6e-135 P cobalt transport protein
JKHLMKBD_01392 2.7e-177 cbiM P PDGLE domain
JKHLMKBD_01393 8.3e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
JKHLMKBD_01394 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JKHLMKBD_01395 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
JKHLMKBD_01396 6.6e-78 ureE O enzyme active site formation
JKHLMKBD_01397 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
JKHLMKBD_01398 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
JKHLMKBD_01399 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
JKHLMKBD_01400 6.8e-95 ureI S AmiS/UreI family transporter
JKHLMKBD_01401 5.1e-45 yhaI L Membrane
JKHLMKBD_01402 3.5e-84 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JKHLMKBD_01403 1.8e-27 comA V protein secretion by the type I secretion system
JKHLMKBD_01404 1.6e-25 V protein secretion by the type I secretion system
JKHLMKBD_01405 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JKHLMKBD_01406 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JKHLMKBD_01407 1.9e-33 V protein secretion by the type I secretion system
JKHLMKBD_01408 3.3e-161 K sequence-specific DNA binding
JKHLMKBD_01409 8.3e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
JKHLMKBD_01410 3.9e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JKHLMKBD_01411 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JKHLMKBD_01412 1.5e-247 trkA P Potassium transporter peripheral membrane component
JKHLMKBD_01413 1.2e-258 trkH P Cation transport protein
JKHLMKBD_01414 1.8e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
JKHLMKBD_01415 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JKHLMKBD_01416 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JKHLMKBD_01417 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JKHLMKBD_01418 1.1e-136 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
JKHLMKBD_01419 7.8e-85 ykuL S CBS domain
JKHLMKBD_01420 3.5e-99 XK27_09740 S Phosphoesterase
JKHLMKBD_01421 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JKHLMKBD_01422 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JKHLMKBD_01423 7.6e-36 yneF S UPF0154 protein
JKHLMKBD_01424 8.1e-91 K transcriptional regulator
JKHLMKBD_01425 4.8e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JKHLMKBD_01428 1.5e-97 ybhL S Belongs to the BI1 family
JKHLMKBD_01429 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
JKHLMKBD_01430 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JKHLMKBD_01431 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JKHLMKBD_01432 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JKHLMKBD_01433 5.2e-59 L Integrase core domain protein
JKHLMKBD_01434 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JKHLMKBD_01435 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JKHLMKBD_01436 9.3e-46 XK27_09675 K -acetyltransferase
JKHLMKBD_01437 3.1e-20 XK27_09675 K -acetyltransferase
JKHLMKBD_01438 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JKHLMKBD_01439 2.5e-23
JKHLMKBD_01440 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
JKHLMKBD_01441 8.5e-297 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
JKHLMKBD_01442 2.4e-220 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JKHLMKBD_01443 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JKHLMKBD_01444 1.5e-94 ypsA S Belongs to the UPF0398 family
JKHLMKBD_01445 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JKHLMKBD_01446 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JKHLMKBD_01447 5.1e-259 pepC 3.4.22.40 E aminopeptidase
JKHLMKBD_01448 3.2e-77 yhaI L Membrane
JKHLMKBD_01449 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JKHLMKBD_01450 8.2e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JKHLMKBD_01451 1.1e-65 S COG1073 Hydrolases of the alpha beta superfamily
JKHLMKBD_01452 6.5e-67 S COG1073 Hydrolases of the alpha beta superfamily
JKHLMKBD_01453 2e-24 S COG1073 Hydrolases of the alpha beta superfamily
JKHLMKBD_01454 7.6e-41 K transcriptional
JKHLMKBD_01455 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JKHLMKBD_01456 3.9e-21 glcR K transcriptional regulator (DeoR family)
JKHLMKBD_01457 4.7e-79 glcR K transcriptional regulator (DeoR family)
JKHLMKBD_01458 1.9e-31 cof Q phosphatase activity
JKHLMKBD_01459 4.9e-45 cof Q phosphatase activity
JKHLMKBD_01460 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
JKHLMKBD_01461 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
JKHLMKBD_01462 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
JKHLMKBD_01463 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JKHLMKBD_01464 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JKHLMKBD_01465 6.8e-56 S TM2 domain
JKHLMKBD_01466 4.7e-43
JKHLMKBD_01469 7.8e-69 L Transposase
JKHLMKBD_01470 1.2e-51 L Transposase
JKHLMKBD_01471 2.9e-94 V VanZ like family
JKHLMKBD_01472 2.9e-16 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JKHLMKBD_01473 2.2e-69 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
JKHLMKBD_01474 5.3e-43 G alpha-ribazole phosphatase activity
JKHLMKBD_01475 1.3e-199 S hmm pf01594
JKHLMKBD_01476 1.3e-17 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JKHLMKBD_01477 3.8e-96 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JKHLMKBD_01478 2.1e-35 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JKHLMKBD_01479 4.9e-39 S granule-associated protein
JKHLMKBD_01480 3.7e-293 S unusual protein kinase
JKHLMKBD_01481 3.4e-29 estA E Lysophospholipase L1 and related esterases
JKHLMKBD_01482 1.8e-69 estA E GDSL-like protein
JKHLMKBD_01483 1.2e-157 rssA S Phospholipase, patatin family
JKHLMKBD_01484 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
JKHLMKBD_01485 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
JKHLMKBD_01486 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
JKHLMKBD_01487 5.9e-22 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
JKHLMKBD_01488 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JKHLMKBD_01489 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JKHLMKBD_01490 3.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JKHLMKBD_01491 0.0 S the current gene model (or a revised gene model) may contain a frame shift
JKHLMKBD_01492 1e-240 cas3 L CRISPR-associated helicase, Cas3
JKHLMKBD_01493 3.6e-46 hpk9 2.7.13.3 T protein histidine kinase activity
JKHLMKBD_01494 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
JKHLMKBD_01495 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JKHLMKBD_01496 3.5e-199 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JKHLMKBD_01497 0.0 lpdA 1.8.1.4 C Dehydrogenase
JKHLMKBD_01498 9.9e-12 3.5.1.28 NU amidase activity
JKHLMKBD_01499 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
JKHLMKBD_01500 2.5e-265 3.5.1.28 NU amidase activity
JKHLMKBD_01501 2.5e-26 3.5.1.28 M GBS Bsp-like repeat
JKHLMKBD_01502 1.5e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JKHLMKBD_01503 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JKHLMKBD_01504 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JKHLMKBD_01505 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JKHLMKBD_01506 1.5e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JKHLMKBD_01507 1e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKHLMKBD_01508 5.6e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKHLMKBD_01509 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
JKHLMKBD_01510 2e-178 fatB P ABC-type enterochelin transport system, periplasmic component
JKHLMKBD_01511 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
JKHLMKBD_01512 5.6e-233 ycdB P peroxidase
JKHLMKBD_01513 8.8e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
JKHLMKBD_01514 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JKHLMKBD_01515 4.6e-25 tatA U protein secretion
JKHLMKBD_01516 2.3e-23 L Transposase
JKHLMKBD_01517 1.3e-48 malR K Transcriptional regulator
JKHLMKBD_01518 1.1e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
JKHLMKBD_01519 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
JKHLMKBD_01520 3.7e-09
JKHLMKBD_01521 1.1e-17
JKHLMKBD_01522 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
JKHLMKBD_01523 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
JKHLMKBD_01524 0.0 pepN 3.4.11.2 E aminopeptidase
JKHLMKBD_01525 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
JKHLMKBD_01526 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JKHLMKBD_01527 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JKHLMKBD_01528 1.2e-155 pstA P phosphate transport system permease
JKHLMKBD_01529 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
JKHLMKBD_01530 3.3e-158 pstS P phosphate
JKHLMKBD_01531 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
JKHLMKBD_01532 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
JKHLMKBD_01533 1.9e-43 yktA S Belongs to the UPF0223 family
JKHLMKBD_01534 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JKHLMKBD_01535 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JKHLMKBD_01536 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JKHLMKBD_01537 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
JKHLMKBD_01538 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
JKHLMKBD_01539 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
JKHLMKBD_01540 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JKHLMKBD_01541 9.3e-62 S haloacid dehalogenase-like hydrolase
JKHLMKBD_01542 1.8e-59 Q phosphatase activity
JKHLMKBD_01543 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
JKHLMKBD_01544 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JKHLMKBD_01545 1.8e-240 agcS E (Alanine) symporter
JKHLMKBD_01546 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JKHLMKBD_01547 1.4e-104 yfiF3 K sequence-specific DNA binding
JKHLMKBD_01548 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
JKHLMKBD_01549 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
JKHLMKBD_01551 1.5e-69 yecS P ABC transporter (Permease
JKHLMKBD_01552 2.8e-15 dtpT E transporter
JKHLMKBD_01553 1.6e-177 dtpT E transporter
JKHLMKBD_01554 7.8e-36 dtpT E transporter
JKHLMKBD_01556 2.1e-63 nylA 3.5.1.4 J Belongs to the amidase family
JKHLMKBD_01557 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JKHLMKBD_01558 8e-123 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JKHLMKBD_01559 9.5e-32 csm6 S Psort location Cytoplasmic, score
JKHLMKBD_01560 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
JKHLMKBD_01561 1.3e-165 csm4 L CRISPR-associated RAMP protein, Csm4 family
JKHLMKBD_01562 1.1e-116 csm3 L RAMP superfamily
JKHLMKBD_01563 5.6e-62 csm2 L Pfam:DUF310
JKHLMKBD_01564 0.0 csm1 S CRISPR-associated protein Csm1 family
JKHLMKBD_01565 8.9e-133 cas6 S Pfam:DUF2276
JKHLMKBD_01566 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JKHLMKBD_01567 1.2e-180 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JKHLMKBD_01568 4.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JKHLMKBD_01569 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
JKHLMKBD_01570 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
JKHLMKBD_01571 1.3e-62 S TraX protein
JKHLMKBD_01572 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
JKHLMKBD_01574 4.8e-41 dinF V Mate efflux family protein
JKHLMKBD_01575 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
JKHLMKBD_01576 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
JKHLMKBD_01577 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
JKHLMKBD_01578 1.2e-143 2.4.2.3 F Phosphorylase superfamily
JKHLMKBD_01581 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
JKHLMKBD_01582 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
JKHLMKBD_01583 6e-08 S Hydrolases of the alpha beta superfamily
JKHLMKBD_01584 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
JKHLMKBD_01585 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JKHLMKBD_01586 1.8e-159 czcD P cation diffusion facilitator family transporter
JKHLMKBD_01587 9e-98 K Transcriptional regulator, TetR family
JKHLMKBD_01588 1.6e-10
JKHLMKBD_01589 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JKHLMKBD_01590 6.4e-104 V ABC transporter (Permease
JKHLMKBD_01591 2.9e-82 L Integrase core domain protein
JKHLMKBD_01592 2.7e-28 L transposition
JKHLMKBD_01593 1.1e-92 L Transposase
JKHLMKBD_01594 1.7e-162 L Transposase
JKHLMKBD_01595 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JKHLMKBD_01596 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JKHLMKBD_01597 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JKHLMKBD_01598 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
JKHLMKBD_01600 2.7e-61 divIC D Septum formation initiator
JKHLMKBD_01601 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
JKHLMKBD_01602 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JKHLMKBD_01603 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JKHLMKBD_01604 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JKHLMKBD_01605 1.1e-29 yyzM S Protein conserved in bacteria
JKHLMKBD_01606 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JKHLMKBD_01607 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JKHLMKBD_01608 8.5e-134 parB K Belongs to the ParB family
JKHLMKBD_01609 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
JKHLMKBD_01610 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JKHLMKBD_01611 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
JKHLMKBD_01615 0.0 XK27_10405 S Bacterial membrane protein YfhO
JKHLMKBD_01616 6.7e-306 ybiT S abc transporter atp-binding protein
JKHLMKBD_01617 1.1e-153 yvjA S membrane
JKHLMKBD_01618 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
JKHLMKBD_01619 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
JKHLMKBD_01620 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JKHLMKBD_01621 1.6e-45 yaaA S S4 domain protein YaaA
JKHLMKBD_01622 4.8e-235 ymfF S Peptidase M16
JKHLMKBD_01623 3.1e-242 ymfH S Peptidase M16
JKHLMKBD_01624 6.3e-138 ymfM S sequence-specific DNA binding
JKHLMKBD_01625 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JKHLMKBD_01626 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JKHLMKBD_01627 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JKHLMKBD_01628 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JKHLMKBD_01629 5.3e-85 lytE M LysM domain protein
JKHLMKBD_01630 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
JKHLMKBD_01631 0.0 S Bacterial membrane protein, YfhO
JKHLMKBD_01632 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JKHLMKBD_01633 1.5e-77 F NUDIX domain
JKHLMKBD_01634 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JKHLMKBD_01635 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JKHLMKBD_01636 3.9e-70 rplI J binds to the 23S rRNA
JKHLMKBD_01637 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JKHLMKBD_01638 8.2e-48 veg S Biofilm formation stimulator VEG
JKHLMKBD_01639 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JKHLMKBD_01640 2.7e-08
JKHLMKBD_01641 4.8e-55 ypaA M Membrane
JKHLMKBD_01642 6.4e-96 XK27_06935 K transcriptional regulator
JKHLMKBD_01643 3.9e-161 XK27_06930 V domain protein
JKHLMKBD_01644 1.8e-88 S Putative adhesin
JKHLMKBD_01645 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
JKHLMKBD_01647 1.7e-23 K negative regulation of transcription, DNA-templated
JKHLMKBD_01648 4e-19 K negative regulation of transcription, DNA-templated
JKHLMKBD_01649 3.4e-13 nudL L hydrolase
JKHLMKBD_01650 4.1e-98 nudL L hydrolase
JKHLMKBD_01651 4.9e-12 K CsbD-like
JKHLMKBD_01652 1.5e-71 M Protein conserved in bacteria
JKHLMKBD_01653 1.8e-23 S Small integral membrane protein
JKHLMKBD_01654 3.1e-101
JKHLMKBD_01655 3.7e-27 S Membrane
JKHLMKBD_01657 2.7e-95 S Hydrophobic domain protein
JKHLMKBD_01658 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
JKHLMKBD_01660 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JKHLMKBD_01661 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JKHLMKBD_01662 9.2e-36 metE 2.1.1.14 E Methionine synthase
JKHLMKBD_01663 7.6e-64 metE 2.1.1.14 E Methionine synthase
JKHLMKBD_01664 5.7e-52 metE 2.1.1.14 E Methionine synthase
JKHLMKBD_01665 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
JKHLMKBD_01667 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
JKHLMKBD_01668 9.9e-169 XK27_01785 S cog cog1284
JKHLMKBD_01669 1.8e-147 yaaA S Belongs to the UPF0246 family
JKHLMKBD_01670 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JKHLMKBD_01671 3.4e-91 XK27_10930 K acetyltransferase
JKHLMKBD_01672 7.5e-14
JKHLMKBD_01673 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
JKHLMKBD_01674 3.6e-299 ccs S the current gene model (or a revised gene model) may contain a frame shift
JKHLMKBD_01675 4.2e-44 yrzB S Belongs to the UPF0473 family
JKHLMKBD_01676 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JKHLMKBD_01677 2.8e-44 yrzL S Belongs to the UPF0297 family
JKHLMKBD_01678 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JKHLMKBD_01679 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
JKHLMKBD_01681 2.2e-132 int L Belongs to the 'phage' integrase family
JKHLMKBD_01682 1.3e-60 K sequence-specific DNA binding
JKHLMKBD_01683 3.9e-287 V ABC transporter transmembrane region
JKHLMKBD_01684 3.4e-191 C Radical SAM
JKHLMKBD_01685 1.1e-15 C Radical SAM
JKHLMKBD_01687 1.4e-127 Z012_04635 K sequence-specific DNA binding
JKHLMKBD_01688 3.3e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JKHLMKBD_01689 2.1e-280 V ABC transporter
JKHLMKBD_01690 5.8e-97 KLT serine threonine protein kinase
JKHLMKBD_01691 1.9e-121 L Transposase
JKHLMKBD_01692 3.4e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
JKHLMKBD_01693 2e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JKHLMKBD_01694 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JKHLMKBD_01695 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JKHLMKBD_01696 6.4e-118 S HAD hydrolase, family IA, variant
JKHLMKBD_01697 2e-157 rrmA 2.1.1.187 Q methyltransferase
JKHLMKBD_01700 7.8e-88 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JKHLMKBD_01701 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JKHLMKBD_01702 6.4e-37 yeeD O sulfur carrier activity
JKHLMKBD_01703 1.8e-187 yeeE S Sulphur transport
JKHLMKBD_01704 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JKHLMKBD_01705 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JKHLMKBD_01706 4.1e-09 S Domain of unknown function (DUF4651)
JKHLMKBD_01707 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
JKHLMKBD_01708 1.5e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JKHLMKBD_01709 1.8e-111 S CAAX amino terminal protease family protein
JKHLMKBD_01711 1.9e-66 V CAAX protease self-immunity
JKHLMKBD_01712 1.4e-33 V CAAX protease self-immunity
JKHLMKBD_01714 6.4e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JKHLMKBD_01715 5.9e-177 ytxK 2.1.1.72 L DNA methylase
JKHLMKBD_01716 2e-12 comGF U Putative Competence protein ComGF
JKHLMKBD_01717 1.5e-71 comGF U Competence protein ComGF
JKHLMKBD_01718 1.4e-15 NU Type II secretory pathway pseudopilin
JKHLMKBD_01719 1.8e-57 cglD NU Competence protein
JKHLMKBD_01720 8.5e-43 comGC U Required for transformation and DNA binding
JKHLMKBD_01721 3e-145 cglB NU type II secretion system
JKHLMKBD_01722 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JKHLMKBD_01723 3.2e-67 S cog cog4699
JKHLMKBD_01724 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JKHLMKBD_01725 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JKHLMKBD_01726 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JKHLMKBD_01727 1e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JKHLMKBD_01728 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JKHLMKBD_01729 3.2e-75 ilvN 2.2.1.6 E Acetolactate synthase
JKHLMKBD_01730 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
JKHLMKBD_01731 8.3e-246 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JKHLMKBD_01732 3.3e-11 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JKHLMKBD_01733 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
JKHLMKBD_01734 1.8e-57 asp S cog cog1302
JKHLMKBD_01735 9.3e-226 norN V Mate efflux family protein
JKHLMKBD_01736 6.4e-279 thrC 4.2.3.1 E Threonine synthase
JKHLMKBD_01737 3.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JKHLMKBD_01738 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
JKHLMKBD_01739 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JKHLMKBD_01740 8.2e-132 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JKHLMKBD_01741 3.1e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
JKHLMKBD_01742 0.0 pepO 3.4.24.71 O Peptidase family M13
JKHLMKBD_01743 1.6e-114 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JKHLMKBD_01744 3.1e-36 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JKHLMKBD_01745 1.4e-54 treB 2.7.1.201 G PTS System
JKHLMKBD_01746 5.8e-21 treR K DNA-binding transcription factor activity
JKHLMKBD_01747 8.6e-87 treR K trehalose operon
JKHLMKBD_01748 3.3e-95 ywlG S Belongs to the UPF0340 family
JKHLMKBD_01751 1.8e-127 tnp L Transposase
JKHLMKBD_01752 2e-20 S phage tail
JKHLMKBD_01753 7.1e-130 S EcsC protein family
JKHLMKBD_01754 2.4e-23 S phage tail tape measure protein
JKHLMKBD_01755 9.8e-71 L Phage integrase family
JKHLMKBD_01757 5e-73 L PFAM Integrase, catalytic core
JKHLMKBD_01758 2.8e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
JKHLMKBD_01760 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
JKHLMKBD_01761 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
JKHLMKBD_01762 6.3e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
JKHLMKBD_01763 3.3e-09 L PFAM Integrase, catalytic core
JKHLMKBD_01764 5.9e-33 L PFAM Integrase, catalytic core
JKHLMKBD_01765 1e-61 L PFAM Integrase, catalytic core
JKHLMKBD_01766 3.3e-62 rplQ J ribosomal protein l17
JKHLMKBD_01767 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JKHLMKBD_01768 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JKHLMKBD_01769 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JKHLMKBD_01770 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JKHLMKBD_01771 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JKHLMKBD_01772 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JKHLMKBD_01773 5.1e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JKHLMKBD_01774 4.4e-58 rplO J binds to the 23S rRNA
JKHLMKBD_01775 2.5e-23 rpmD J ribosomal protein l30
JKHLMKBD_01776 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JKHLMKBD_01777 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JKHLMKBD_01778 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JKHLMKBD_01779 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JKHLMKBD_01780 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JKHLMKBD_01781 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JKHLMKBD_01782 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JKHLMKBD_01783 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JKHLMKBD_01784 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JKHLMKBD_01785 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
JKHLMKBD_01786 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JKHLMKBD_01787 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JKHLMKBD_01788 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JKHLMKBD_01789 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JKHLMKBD_01790 4.4e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JKHLMKBD_01791 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JKHLMKBD_01792 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
JKHLMKBD_01793 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JKHLMKBD_01794 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
JKHLMKBD_01795 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JKHLMKBD_01796 0.0 XK27_09800 I Acyltransferase
JKHLMKBD_01797 1.7e-35 XK27_09805 S MORN repeat protein
JKHLMKBD_01798 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JKHLMKBD_01799 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JKHLMKBD_01800 8.8e-83 adk 2.7.4.3 F topology modulation protein
JKHLMKBD_01801 2e-171 yxaM EGP Major facilitator Superfamily
JKHLMKBD_01802 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
JKHLMKBD_01803 1.3e-87 L Transposase
JKHLMKBD_01804 5.4e-20 rmlC 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
JKHLMKBD_01805 3e-159 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JKHLMKBD_01806 7.3e-248 cps1C S Polysaccharide biosynthesis protein
JKHLMKBD_01807 5.2e-142 cps1B GT2,GT4 M Glycosyl transferases group 1
JKHLMKBD_01808 1.7e-36 S Psort location CytoplasmicMembrane, score 9.99
JKHLMKBD_01809 2.9e-80 sacB GT2,GT4 M transferase activity, transferring glycosyl groups
JKHLMKBD_01810 1.3e-59 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
JKHLMKBD_01811 4.8e-150 M Glycosyltransferase, group 2 family protein
JKHLMKBD_01812 1.7e-90 Z012_10770 M Domain of unknown function (DUF1919)
JKHLMKBD_01813 2.6e-211 wcoF M Glycosyltransferase, group 1 family protein
JKHLMKBD_01814 5.9e-219 rgpAc GT4 M group 1 family protein
JKHLMKBD_01815 8.8e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
JKHLMKBD_01816 7.7e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
JKHLMKBD_01817 5.3e-111 cps4C M biosynthesis protein
JKHLMKBD_01818 5.1e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
JKHLMKBD_01819 1.9e-251 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
JKHLMKBD_01820 3.1e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
JKHLMKBD_01821 7e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
JKHLMKBD_01822 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
JKHLMKBD_01823 4e-64 clcA_2 P chloride
JKHLMKBD_01824 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JKHLMKBD_01825 8.1e-41 S Protein of unknown function (DUF1697)
JKHLMKBD_01826 3.8e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JKHLMKBD_01827 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JKHLMKBD_01829 6.1e-22 V Glucan-binding protein C
JKHLMKBD_01830 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
JKHLMKBD_01831 9e-275 pepV 3.5.1.18 E Dipeptidase
JKHLMKBD_01832 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
JKHLMKBD_01833 6.9e-86 XK27_03610 K Gnat family
JKHLMKBD_01834 9.1e-10 L COG1943 Transposase and inactivated derivatives
JKHLMKBD_01835 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JKHLMKBD_01836 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JKHLMKBD_01837 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JKHLMKBD_01838 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JKHLMKBD_01839 2.8e-18 M LysM domain
JKHLMKBD_01840 2.9e-90 ebsA S Family of unknown function (DUF5322)
JKHLMKBD_01841 4.2e-228 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JKHLMKBD_01842 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JKHLMKBD_01843 2.4e-223 G COG0457 FOG TPR repeat
JKHLMKBD_01844 6.2e-176 yubA S permease
JKHLMKBD_01845 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
JKHLMKBD_01846 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
JKHLMKBD_01847 2.5e-124 ftsE D cell division ATP-binding protein FtsE
JKHLMKBD_01848 3.7e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JKHLMKBD_01849 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JKHLMKBD_01850 4.3e-180 yjjH S Calcineurin-like phosphoesterase
JKHLMKBD_01851 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
JKHLMKBD_01852 0.0 pacL 3.6.3.8 P cation transport ATPase
JKHLMKBD_01853 2.6e-67 ywiB S Domain of unknown function (DUF1934)
JKHLMKBD_01854 9.1e-50 XK27_00115 2.3.1.128 K acetyltransferase
JKHLMKBD_01855 9.2e-147 yidA S hydrolases of the HAD superfamily
JKHLMKBD_01856 2e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
JKHLMKBD_01857 5e-35 F Protein of unknown function (DUF454)
JKHLMKBD_01858 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
JKHLMKBD_01859 1.5e-247 vicK 2.7.13.3 T Histidine kinase
JKHLMKBD_01860 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JKHLMKBD_01861 3.3e-138 glnQ 3.6.3.21 E abc transporter atp-binding protein
JKHLMKBD_01862 4.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
JKHLMKBD_01863 5.9e-118 gltJ P ABC transporter (Permease
JKHLMKBD_01864 1.7e-111 tcyB_2 P ABC transporter (permease)
JKHLMKBD_01865 2.4e-124 endA F DNA RNA non-specific endonuclease
JKHLMKBD_01866 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
JKHLMKBD_01867 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JKHLMKBD_01869 6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JKHLMKBD_01870 1.7e-36 5.1.3.2 GM Psort location CytoplasmicMembrane, score
JKHLMKBD_01871 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JKHLMKBD_01872 1.2e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JKHLMKBD_01873 9.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JKHLMKBD_01874 6.1e-88 ytsP 1.8.4.14 T GAF domain-containing protein
JKHLMKBD_01875 1.3e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JKHLMKBD_01876 7.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
JKHLMKBD_01878 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JKHLMKBD_01879 2.1e-219 XK27_05110 P chloride
JKHLMKBD_01880 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
JKHLMKBD_01881 6.4e-282 clcA P Chloride transporter, ClC family
JKHLMKBD_01882 2.3e-75 fld C Flavodoxin
JKHLMKBD_01884 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
JKHLMKBD_01885 3.5e-151 estA CE1 S Putative esterase
JKHLMKBD_01886 1.1e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JKHLMKBD_01887 1.2e-135 XK27_08845 S abc transporter atp-binding protein
JKHLMKBD_01888 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
JKHLMKBD_01889 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
JKHLMKBD_01890 1.6e-16 S Domain of unknown function (DUF4649)
JKHLMKBD_01892 1.6e-31 Q the current gene model (or a revised gene model) may contain a frame shift
JKHLMKBD_01893 2.7e-26 Q the current gene model (or a revised gene model) may contain a frame shift
JKHLMKBD_01894 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
JKHLMKBD_01896 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
JKHLMKBD_01897 3.1e-27 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JKHLMKBD_01898 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
JKHLMKBD_01899 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
JKHLMKBD_01900 0.0 uup S abc transporter atp-binding protein
JKHLMKBD_01901 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
JKHLMKBD_01902 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JKHLMKBD_01903 8.7e-150 cobQ S glutamine amidotransferase
JKHLMKBD_01904 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
JKHLMKBD_01905 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JKHLMKBD_01906 6e-169 ybbR S Protein conserved in bacteria
JKHLMKBD_01907 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JKHLMKBD_01908 1.7e-70 gtrA S GtrA-like protein
JKHLMKBD_01909 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
JKHLMKBD_01910 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JKHLMKBD_01911 2.4e-100 zupT P Mediates zinc uptake. May also transport other divalent cations
JKHLMKBD_01912 1.1e-206 yurR 1.4.5.1 E oxidoreductase
JKHLMKBD_01913 4.1e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JKHLMKBD_01914 1.9e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
JKHLMKBD_01915 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JKHLMKBD_01919 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
JKHLMKBD_01920 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
JKHLMKBD_01921 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JKHLMKBD_01922 1.1e-121 ylfI S tigr01906
JKHLMKBD_01923 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
JKHLMKBD_01924 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
JKHLMKBD_01925 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
JKHLMKBD_01926 7.4e-21 XK27_08085
JKHLMKBD_01927 5.2e-36 L transposase activity
JKHLMKBD_01928 1.8e-21 L Transposase
JKHLMKBD_01929 5.3e-56 L transposition
JKHLMKBD_01930 1.9e-86 L Integrase core domain protein
JKHLMKBD_01932 4.1e-195 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JKHLMKBD_01933 1.5e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JKHLMKBD_01934 2.7e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
JKHLMKBD_01935 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JKHLMKBD_01936 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
JKHLMKBD_01937 3.2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JKHLMKBD_01938 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JKHLMKBD_01939 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JKHLMKBD_01940 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JKHLMKBD_01941 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
JKHLMKBD_01942 5.6e-240 rodA D Belongs to the SEDS family
JKHLMKBD_01943 8e-31 L transposase, IS4 family
JKHLMKBD_01944 1.7e-150 L transposase, IS4 family
JKHLMKBD_01945 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JKHLMKBD_01946 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
JKHLMKBD_01947 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JKHLMKBD_01948 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JKHLMKBD_01949 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
JKHLMKBD_01950 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JKHLMKBD_01951 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JKHLMKBD_01952 2.9e-125 dnaD
JKHLMKBD_01953 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JKHLMKBD_01956 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JKHLMKBD_01957 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
JKHLMKBD_01958 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JKHLMKBD_01959 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
JKHLMKBD_01960 1.8e-72 argR K Regulates arginine biosynthesis genes
JKHLMKBD_01961 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
JKHLMKBD_01962 1e-148 DegV S DegV family
JKHLMKBD_01963 6e-144 ypmR E lipolytic protein G-D-S-L family
JKHLMKBD_01964 2.1e-84 ypmS S Protein conserved in bacteria
JKHLMKBD_01965 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JKHLMKBD_01967 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
JKHLMKBD_01968 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JKHLMKBD_01969 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JKHLMKBD_01970 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
JKHLMKBD_01971 2.5e-43 ysdA L Membrane
JKHLMKBD_01972 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JKHLMKBD_01973 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JKHLMKBD_01974 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
JKHLMKBD_01975 0.0 dnaE 2.7.7.7 L DNA polymerase
JKHLMKBD_01976 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JKHLMKBD_01977 3.9e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)