ORF_ID e_value Gene_name EC_number CAZy COGs Description
NFMMICNG_00001 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NFMMICNG_00002 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NFMMICNG_00003 1.8e-37 yaaB S Domain of unknown function (DUF370)
NFMMICNG_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NFMMICNG_00005 2.4e-33 yaaA S S4 domain
NFMMICNG_00006 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NFMMICNG_00007 7.8e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NFMMICNG_00008 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NFMMICNG_00009 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NFMMICNG_00010 6.5e-108 jag S single-stranded nucleic acid binding R3H
NFMMICNG_00011 5.8e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NFMMICNG_00012 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NFMMICNG_00013 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NFMMICNG_00014 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NFMMICNG_00015 9.6e-74 S Bacterial PH domain
NFMMICNG_00016 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NFMMICNG_00017 2.1e-149 spo0J K Belongs to the ParB family
NFMMICNG_00018 1.6e-111 yyaC S Sporulation protein YyaC
NFMMICNG_00019 8.1e-177 yyaD S Membrane
NFMMICNG_00020 2.3e-33 yyzM S protein conserved in bacteria
NFMMICNG_00021 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NFMMICNG_00022 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NFMMICNG_00023 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NFMMICNG_00024 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NFMMICNG_00025 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NFMMICNG_00026 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
NFMMICNG_00027 8.9e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NFMMICNG_00028 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFMMICNG_00029 1.1e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NFMMICNG_00030 2.3e-243 EGP Major facilitator superfamily
NFMMICNG_00031 3.6e-168 yyaK S CAAX protease self-immunity
NFMMICNG_00032 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NFMMICNG_00033 2.8e-160 yyaM EG EamA-like transporter family
NFMMICNG_00034 5.1e-61 yyaN K MerR HTH family regulatory protein
NFMMICNG_00035 4.1e-11 S Putative amidase domain
NFMMICNG_00037 2.3e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NFMMICNG_00038 6.6e-246 tetL EGP Major facilitator Superfamily
NFMMICNG_00039 2.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
NFMMICNG_00040 1.3e-65 yyaQ S YjbR
NFMMICNG_00041 1.6e-91 yyaR K Acetyltransferase (GNAT) domain
NFMMICNG_00042 5.5e-96 yyaS S Membrane
NFMMICNG_00043 2e-71 yjcF S Acetyltransferase (GNAT) domain
NFMMICNG_00044 5.6e-77 yybA 2.3.1.57 K transcriptional
NFMMICNG_00045 7.3e-126 S Metallo-beta-lactamase superfamily
NFMMICNG_00046 1.6e-74 yybC
NFMMICNG_00047 7.7e-79 yjcF S Acetyltransferase (GNAT) domain
NFMMICNG_00048 4e-164 yybE K Transcriptional regulator
NFMMICNG_00049 2.2e-216 ynfM EGP Major facilitator Superfamily
NFMMICNG_00050 3.5e-54 yybG S Pentapeptide repeat-containing protein
NFMMICNG_00051 2.9e-66 yybH S SnoaL-like domain
NFMMICNG_00052 4.8e-124
NFMMICNG_00053 2.2e-110 K TipAS antibiotic-recognition domain
NFMMICNG_00054 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NFMMICNG_00056 3.6e-60
NFMMICNG_00057 8.1e-163 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NFMMICNG_00058 1.7e-66 ydeP3 K Transcriptional regulator
NFMMICNG_00059 3.3e-83 cotF M Spore coat protein
NFMMICNG_00061 8.3e-160 yybS S membrane
NFMMICNG_00062 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NFMMICNG_00063 2.2e-73 rplI J binds to the 23S rRNA
NFMMICNG_00064 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NFMMICNG_00065 8.4e-221 yeaN P COG2807 Cyanate permease
NFMMICNG_00066 1.9e-15 yycC K YycC-like protein
NFMMICNG_00068 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NFMMICNG_00069 1.2e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NFMMICNG_00070 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFMMICNG_00071 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NFMMICNG_00076 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFMMICNG_00077 0.0 vicK 2.7.13.3 T Histidine kinase
NFMMICNG_00078 3.1e-259 yycH S protein conserved in bacteria
NFMMICNG_00079 1.8e-153 yycI S protein conserved in bacteria
NFMMICNG_00080 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NFMMICNG_00081 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NFMMICNG_00082 5.5e-33 S Peptidase propeptide and YPEB domain
NFMMICNG_00083 2.6e-73 S Peptidase propeptide and YPEB domain
NFMMICNG_00084 1.5e-94 K PFAM response regulator receiver
NFMMICNG_00085 2.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
NFMMICNG_00086 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NFMMICNG_00087 1.5e-40 sdpR K transcriptional
NFMMICNG_00088 1.5e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NFMMICNG_00089 2.3e-24 S Sporulation delaying protein SdpA
NFMMICNG_00090 2.8e-94
NFMMICNG_00091 7.4e-16
NFMMICNG_00092 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NFMMICNG_00093 1.3e-260 rocE E amino acid
NFMMICNG_00094 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NFMMICNG_00096 1.1e-187 S aspartate phosphatase
NFMMICNG_00097 1.4e-83 yycN 2.3.1.128 K Acetyltransferase
NFMMICNG_00098 8.4e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NFMMICNG_00099 5.4e-201 yycP
NFMMICNG_00100 1.7e-30 yycQ S Protein of unknown function (DUF2651)
NFMMICNG_00102 3.9e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NFMMICNG_00103 1.3e-67
NFMMICNG_00104 1.1e-09 S YyzF-like protein
NFMMICNG_00105 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NFMMICNG_00106 1.1e-180 L DNA synthesis involved in DNA repair
NFMMICNG_00107 1.3e-202 S SIR2-like domain
NFMMICNG_00108 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NFMMICNG_00109 1.6e-109 prrC P ABC transporter
NFMMICNG_00110 1.6e-118 S ABC-2 family transporter protein
NFMMICNG_00111 1.9e-124 yydK K Transcriptional regulator
NFMMICNG_00112 3.4e-27 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
NFMMICNG_00113 5.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NFMMICNG_00114 1.9e-286 ahpF O Alkyl hydroperoxide reductase
NFMMICNG_00115 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NFMMICNG_00116 5e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NFMMICNG_00117 1e-230 gntP EG COG2610 H gluconate symporter and related permeases
NFMMICNG_00118 2.8e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NFMMICNG_00119 2.8e-126 gntR K transcriptional
NFMMICNG_00120 1.9e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NFMMICNG_00121 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
NFMMICNG_00122 1.3e-117 yxaC M effector of murein hydrolase
NFMMICNG_00123 5.2e-50 S LrgA family
NFMMICNG_00124 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NFMMICNG_00125 1.9e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NFMMICNG_00126 1.2e-100 yxaF K Transcriptional regulator
NFMMICNG_00127 1.3e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
NFMMICNG_00128 1.4e-228 P Protein of unknown function (DUF418)
NFMMICNG_00129 1.1e-75 yxaI S membrane protein domain
NFMMICNG_00130 3.5e-65 S Family of unknown function (DUF5391)
NFMMICNG_00131 6.8e-93 S PQQ-like domain
NFMMICNG_00132 7.6e-214 yxaM U MFS_1 like family
NFMMICNG_00133 0.0 asnB 6.3.5.4 E Asparagine synthase
NFMMICNG_00134 1.1e-86 yxnB
NFMMICNG_00135 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
NFMMICNG_00136 3.3e-127 yxbB Q Met-10+ like-protein
NFMMICNG_00137 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
NFMMICNG_00138 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
NFMMICNG_00139 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NFMMICNG_00140 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
NFMMICNG_00141 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
NFMMICNG_00143 0.0 htpG O Molecular chaperone. Has ATPase activity
NFMMICNG_00144 2.3e-246 csbC EGP Major facilitator Superfamily
NFMMICNG_00145 8.3e-48 yxcD S Protein of unknown function (DUF2653)
NFMMICNG_00147 8.3e-176 iolS C Aldo keto reductase
NFMMICNG_00148 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NFMMICNG_00149 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NFMMICNG_00150 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NFMMICNG_00151 1.4e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NFMMICNG_00152 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NFMMICNG_00153 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NFMMICNG_00154 5.1e-235 iolF EGP Major facilitator Superfamily
NFMMICNG_00155 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NFMMICNG_00156 8.6e-167 iolH G Xylose isomerase-like TIM barrel
NFMMICNG_00157 2.3e-137 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NFMMICNG_00158 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NFMMICNG_00159 1.2e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFMMICNG_00160 4.8e-182 T PhoQ Sensor
NFMMICNG_00161 9.4e-141 yxdL V ABC transporter, ATP-binding protein
NFMMICNG_00162 0.0 yxdM V ABC transporter (permease)
NFMMICNG_00163 1.5e-58 yxeA S Protein of unknown function (DUF1093)
NFMMICNG_00164 1.9e-175 fhuD P ABC transporter
NFMMICNG_00165 8.5e-69
NFMMICNG_00166 1.9e-16 yxeD
NFMMICNG_00167 1.3e-20 yxeE
NFMMICNG_00170 1.4e-150 yidA S hydrolases of the HAD superfamily
NFMMICNG_00171 1.2e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NFMMICNG_00173 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NFMMICNG_00174 7.5e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NFMMICNG_00175 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
NFMMICNG_00176 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
NFMMICNG_00177 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NFMMICNG_00178 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
NFMMICNG_00179 2e-255 yxeQ S MmgE/PrpD family
NFMMICNG_00180 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
NFMMICNG_00181 1.3e-151 yxxB S Domain of Unknown Function (DUF1206)
NFMMICNG_00182 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NFMMICNG_00183 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NFMMICNG_00184 8.3e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NFMMICNG_00185 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NFMMICNG_00186 1.3e-249 lysP E amino acid
NFMMICNG_00187 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NFMMICNG_00188 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NFMMICNG_00189 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NFMMICNG_00190 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
NFMMICNG_00191 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NFMMICNG_00192 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NFMMICNG_00193 2.1e-21 S Domain of unknown function (DUF5082)
NFMMICNG_00194 3.6e-39 yxiC S Family of unknown function (DUF5344)
NFMMICNG_00195 0.0 S nuclease activity
NFMMICNG_00196 2.2e-78 S SMI1 / KNR4 family
NFMMICNG_00197 3.6e-51
NFMMICNG_00198 4.3e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NFMMICNG_00199 6.2e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NFMMICNG_00200 1.1e-72 yxiE T Belongs to the universal stress protein A family
NFMMICNG_00201 2.9e-168 yxxF EG EamA-like transporter family
NFMMICNG_00202 0.0 wapA M COG3209 Rhs family protein
NFMMICNG_00203 1.5e-71 yxxG
NFMMICNG_00204 1.7e-84
NFMMICNG_00205 6.4e-63
NFMMICNG_00206 3.7e-75 yxiG
NFMMICNG_00207 4.9e-46
NFMMICNG_00208 3.8e-81
NFMMICNG_00209 3e-90 yxiI S Protein of unknown function (DUF2716)
NFMMICNG_00210 1.6e-48 yxiJ S YxiJ-like protein
NFMMICNG_00213 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NFMMICNG_00214 5.6e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NFMMICNG_00215 5.6e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
NFMMICNG_00216 2e-110
NFMMICNG_00217 8.3e-151 licT K transcriptional antiterminator
NFMMICNG_00218 3.6e-142 exoK GH16 M licheninase activity
NFMMICNG_00219 6.6e-224 citH C Citrate transporter
NFMMICNG_00220 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NFMMICNG_00221 3e-47 yxiS
NFMMICNG_00222 1.5e-102 T Domain of unknown function (DUF4163)
NFMMICNG_00223 5.4e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NFMMICNG_00224 5e-142 rlmA 2.1.1.187 Q Methyltransferase domain
NFMMICNG_00225 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
NFMMICNG_00226 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NFMMICNG_00227 3.4e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NFMMICNG_00228 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NFMMICNG_00229 1e-220 yxjG 2.1.1.14 E Methionine synthase
NFMMICNG_00230 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
NFMMICNG_00231 1.4e-86 yxjI S LURP-one-related
NFMMICNG_00233 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NFMMICNG_00234 9.8e-115 K helix_turn_helix, Lux Regulon
NFMMICNG_00235 1.6e-190 yxjM T Signal transduction histidine kinase
NFMMICNG_00236 7.7e-77 S Protein of unknown function (DUF1453)
NFMMICNG_00237 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NFMMICNG_00238 2.8e-74 yxkC S Domain of unknown function (DUF4352)
NFMMICNG_00239 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NFMMICNG_00240 2.5e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NFMMICNG_00241 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
NFMMICNG_00242 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NFMMICNG_00243 9.9e-152 yxkH G Polysaccharide deacetylase
NFMMICNG_00245 2.3e-309 3.4.24.84 O Peptidase family M48
NFMMICNG_00246 2.1e-228 cimH C COG3493 Na citrate symporter
NFMMICNG_00247 6.9e-267 cydA 1.10.3.14 C oxidase, subunit
NFMMICNG_00248 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NFMMICNG_00249 4e-309 cydD V ATP-binding
NFMMICNG_00250 0.0 cydD V ATP-binding protein
NFMMICNG_00251 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NFMMICNG_00252 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NFMMICNG_00253 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NFMMICNG_00254 1.6e-46 yxlC S Family of unknown function (DUF5345)
NFMMICNG_00255 1.4e-30
NFMMICNG_00256 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
NFMMICNG_00257 8.2e-165 yxlF V ABC transporter, ATP-binding protein
NFMMICNG_00258 2.6e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NFMMICNG_00259 1.6e-211 yxlH EGP Major facilitator Superfamily
NFMMICNG_00260 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NFMMICNG_00261 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NFMMICNG_00262 1.1e-19 yxzF
NFMMICNG_00263 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NFMMICNG_00264 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NFMMICNG_00265 7e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NFMMICNG_00266 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NFMMICNG_00267 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NFMMICNG_00268 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NFMMICNG_00269 8.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NFMMICNG_00270 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NFMMICNG_00271 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFMMICNG_00272 3.6e-232 dltB M membrane protein involved in D-alanine export
NFMMICNG_00273 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFMMICNG_00274 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NFMMICNG_00275 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NFMMICNG_00276 8.8e-130 ynfM EGP Major facilitator Superfamily
NFMMICNG_00277 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
NFMMICNG_00278 4e-92 K Helix-turn-helix XRE-family like proteins
NFMMICNG_00279 3.7e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NFMMICNG_00280 3.9e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NFMMICNG_00281 1.2e-86 ywaE K Transcriptional regulator
NFMMICNG_00282 1.5e-124 ywaF S Integral membrane protein
NFMMICNG_00283 4.5e-168 gspA M General stress
NFMMICNG_00284 7.6e-152 sacY K transcriptional antiterminator
NFMMICNG_00285 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NFMMICNG_00286 2.9e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
NFMMICNG_00287 1.4e-240 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NFMMICNG_00288 8.3e-125 ywbB S Protein of unknown function (DUF2711)
NFMMICNG_00289 6.9e-96 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NFMMICNG_00290 9.9e-67 ywbC 4.4.1.5 E glyoxalase
NFMMICNG_00291 3.5e-219 ywbD 2.1.1.191 J Methyltransferase
NFMMICNG_00292 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
NFMMICNG_00293 8.1e-208 ywbF EGP Major facilitator Superfamily
NFMMICNG_00294 2.3e-111 ywbG M effector of murein hydrolase
NFMMICNG_00295 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NFMMICNG_00296 4.3e-153 ywbI K Transcriptional regulator
NFMMICNG_00297 1.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NFMMICNG_00298 4.5e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NFMMICNG_00299 9e-254 P COG0672 High-affinity Fe2 Pb2 permease
NFMMICNG_00300 2e-163 ycdO P periplasmic lipoprotein involved in iron transport
NFMMICNG_00301 3.2e-223 ywbN P Dyp-type peroxidase family protein
NFMMICNG_00302 4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NFMMICNG_00303 6.9e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NFMMICNG_00304 9.8e-49 ywcB S Protein of unknown function, DUF485
NFMMICNG_00306 1.1e-121 ywcC K transcriptional regulator
NFMMICNG_00307 9.5e-60 gtcA S GtrA-like protein
NFMMICNG_00308 1.9e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NFMMICNG_00309 2.6e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NFMMICNG_00310 1e-35 ywzA S membrane
NFMMICNG_00311 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NFMMICNG_00312 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NFMMICNG_00313 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NFMMICNG_00314 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NFMMICNG_00315 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NFMMICNG_00316 8.6e-202 rodA D Belongs to the SEDS family
NFMMICNG_00317 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NFMMICNG_00318 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NFMMICNG_00319 0.0 vpr O Belongs to the peptidase S8 family
NFMMICNG_00321 7e-150 sacT K transcriptional antiterminator
NFMMICNG_00322 6.7e-139 focA P Formate/nitrite transporter
NFMMICNG_00323 1.8e-251 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NFMMICNG_00324 1.4e-283 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NFMMICNG_00325 2e-28 ywdA
NFMMICNG_00326 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NFMMICNG_00327 1.6e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
NFMMICNG_00328 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NFMMICNG_00329 3e-259 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NFMMICNG_00330 6.6e-48 ywdI S Family of unknown function (DUF5327)
NFMMICNG_00331 3.7e-238 ywdJ F Xanthine uracil
NFMMICNG_00332 4.3e-59 ywdK S small membrane protein
NFMMICNG_00333 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NFMMICNG_00334 4.5e-143 spsA M Spore Coat
NFMMICNG_00335 1.4e-267 spsB M Capsule polysaccharide biosynthesis protein
NFMMICNG_00336 1.1e-222 spsC E Belongs to the DegT DnrJ EryC1 family
NFMMICNG_00337 1.7e-162 spsD 2.3.1.210 K Spore Coat
NFMMICNG_00338 6e-213 spsE 2.5.1.56 M acid synthase
NFMMICNG_00339 1e-128 spsF M Spore Coat
NFMMICNG_00340 1.5e-183 spsG M Spore Coat
NFMMICNG_00341 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NFMMICNG_00342 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NFMMICNG_00343 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NFMMICNG_00344 1.3e-86 spsL 5.1.3.13 M Spore Coat
NFMMICNG_00345 3.4e-77
NFMMICNG_00346 8.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NFMMICNG_00347 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NFMMICNG_00348 0.0 rocB E arginine degradation protein
NFMMICNG_00349 4.8e-249 lysP E amino acid
NFMMICNG_00350 6e-206 ywfA EGP Major facilitator Superfamily
NFMMICNG_00351 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NFMMICNG_00352 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NFMMICNG_00353 2.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFMMICNG_00354 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NFMMICNG_00355 1.9e-209 bacE EGP Major facilitator Superfamily
NFMMICNG_00356 5e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
NFMMICNG_00357 1.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
NFMMICNG_00358 1.1e-146 ywfI C May function as heme-dependent peroxidase
NFMMICNG_00359 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NFMMICNG_00360 1.1e-156 cysL K Transcriptional regulator
NFMMICNG_00361 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NFMMICNG_00362 1.6e-155 ywfM EG EamA-like transporter family
NFMMICNG_00363 5.1e-110 rsfA_1
NFMMICNG_00364 3.1e-36 ywzC S Belongs to the UPF0741 family
NFMMICNG_00365 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
NFMMICNG_00366 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
NFMMICNG_00367 6.2e-79 yffB K Transcriptional regulator
NFMMICNG_00368 9.8e-237 mmr U Major Facilitator Superfamily
NFMMICNG_00370 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NFMMICNG_00371 9.5e-71 ywhA K Transcriptional regulator
NFMMICNG_00372 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NFMMICNG_00373 5.1e-119 ywhC S Peptidase family M50
NFMMICNG_00374 5.2e-95 ywhD S YwhD family
NFMMICNG_00375 3.6e-49
NFMMICNG_00376 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NFMMICNG_00377 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NFMMICNG_00378 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
NFMMICNG_00379 3.7e-28 ywhH S Aminoacyl-tRNA editing domain
NFMMICNG_00381 8.9e-79 S aspartate phosphatase
NFMMICNG_00382 3.2e-192 ywhK CO amine dehydrogenase activity
NFMMICNG_00383 4.7e-244 ywhL CO amine dehydrogenase activity
NFMMICNG_00385 1.6e-249 L Peptidase, M16
NFMMICNG_00386 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
NFMMICNG_00387 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NFMMICNG_00388 3.3e-132 cbiO V ABC transporter
NFMMICNG_00390 4.9e-270 C Fe-S oxidoreductases
NFMMICNG_00391 1e-07 S Bacteriocin subtilosin A
NFMMICNG_00392 4.7e-73 ywiB S protein conserved in bacteria
NFMMICNG_00393 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NFMMICNG_00394 2.3e-213 narK P COG2223 Nitrate nitrite transporter
NFMMICNG_00395 7.7e-129 fnr K helix_turn_helix, cAMP Regulatory protein
NFMMICNG_00396 1.7e-139 ywiC S YwiC-like protein
NFMMICNG_00397 7e-86 arfM T cyclic nucleotide binding
NFMMICNG_00398 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NFMMICNG_00399 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
NFMMICNG_00400 1.1e-93 narJ 1.7.5.1 C nitrate reductase
NFMMICNG_00401 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
NFMMICNG_00402 2.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NFMMICNG_00403 0.0 ywjA V ABC transporter
NFMMICNG_00404 4.8e-96 ywjB H RibD C-terminal domain
NFMMICNG_00405 2.7e-42 ywjC
NFMMICNG_00406 3.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NFMMICNG_00407 1.5e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NFMMICNG_00408 0.0 fadF C COG0247 Fe-S oxidoreductase
NFMMICNG_00409 1.3e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NFMMICNG_00410 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NFMMICNG_00411 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NFMMICNG_00412 5.1e-90 ywjG S Domain of unknown function (DUF2529)
NFMMICNG_00413 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NFMMICNG_00414 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NFMMICNG_00415 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NFMMICNG_00416 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NFMMICNG_00417 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NFMMICNG_00418 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NFMMICNG_00419 1.1e-32 rpmE J Binds the 23S rRNA
NFMMICNG_00420 1.6e-103 tdk 2.7.1.21 F thymidine kinase
NFMMICNG_00421 0.0 sfcA 1.1.1.38 C malic enzyme
NFMMICNG_00422 8.6e-160 ywkB S Membrane transport protein
NFMMICNG_00423 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NFMMICNG_00424 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFMMICNG_00425 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NFMMICNG_00426 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NFMMICNG_00428 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
NFMMICNG_00429 6.1e-112 spoIIR S stage II sporulation protein R
NFMMICNG_00430 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NFMMICNG_00431 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NFMMICNG_00432 1.7e-91 mntP P Probably functions as a manganese efflux pump
NFMMICNG_00433 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NFMMICNG_00434 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NFMMICNG_00435 7.2e-95 ywlG S Belongs to the UPF0340 family
NFMMICNG_00436 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NFMMICNG_00437 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NFMMICNG_00438 2.5e-62 atpI S ATP synthase
NFMMICNG_00439 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NFMMICNG_00440 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NFMMICNG_00441 6.4e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NFMMICNG_00442 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NFMMICNG_00443 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NFMMICNG_00444 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NFMMICNG_00445 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NFMMICNG_00446 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NFMMICNG_00447 1.4e-13 ywmA
NFMMICNG_00448 1.3e-60 ywmA
NFMMICNG_00449 1.3e-32 ywzB S membrane
NFMMICNG_00450 2.8e-134 ywmB S TATA-box binding
NFMMICNG_00451 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NFMMICNG_00452 1e-174 spoIID D Stage II sporulation protein D
NFMMICNG_00453 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NFMMICNG_00454 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NFMMICNG_00456 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NFMMICNG_00457 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NFMMICNG_00458 1.3e-103 S response regulator aspartate phosphatase
NFMMICNG_00459 3e-84 ywmF S Peptidase M50
NFMMICNG_00460 3.8e-11 csbD K CsbD-like
NFMMICNG_00462 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NFMMICNG_00463 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NFMMICNG_00464 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NFMMICNG_00465 1.7e-64 ywnA K Transcriptional regulator
NFMMICNG_00466 1.6e-114 ywnB S NAD(P)H-binding
NFMMICNG_00467 2.6e-59 ywnC S Family of unknown function (DUF5362)
NFMMICNG_00468 5e-142 mta K transcriptional
NFMMICNG_00469 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NFMMICNG_00470 2.2e-70 ywnF S Family of unknown function (DUF5392)
NFMMICNG_00471 8.9e-10 ywnC S Family of unknown function (DUF5362)
NFMMICNG_00472 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NFMMICNG_00473 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NFMMICNG_00474 3e-72 ywnJ S VanZ like family
NFMMICNG_00475 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NFMMICNG_00476 1.6e-58 nrgB K Belongs to the P(II) protein family
NFMMICNG_00477 2.5e-225 amt P Ammonium transporter
NFMMICNG_00478 2.2e-76
NFMMICNG_00479 4e-104 phzA Q Isochorismatase family
NFMMICNG_00480 9.8e-242 ywoD EGP Major facilitator superfamily
NFMMICNG_00481 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NFMMICNG_00482 2.8e-231 ywoF P Right handed beta helix region
NFMMICNG_00483 3.9e-210 ywoG EGP Major facilitator Superfamily
NFMMICNG_00484 2.1e-70 ywoH K COG1846 Transcriptional regulators
NFMMICNG_00485 3e-44 spoIIID K Stage III sporulation protein D
NFMMICNG_00486 3.5e-180 mbl D Rod shape-determining protein
NFMMICNG_00487 9.9e-125 flhO N flagellar basal body
NFMMICNG_00488 3.7e-140 flhP N flagellar basal body
NFMMICNG_00489 8.8e-198 S aspartate phosphatase
NFMMICNG_00490 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NFMMICNG_00491 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NFMMICNG_00492 7e-153 ywpD T Histidine kinase
NFMMICNG_00493 1.2e-49 srtA 3.4.22.70 M Sortase family
NFMMICNG_00494 1.1e-66 ywpF S YwpF-like protein
NFMMICNG_00495 3.8e-66 ywpG
NFMMICNG_00496 3.7e-57 ssbB L Single-stranded DNA-binding protein
NFMMICNG_00497 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
NFMMICNG_00498 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NFMMICNG_00499 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NFMMICNG_00500 1.4e-308 ywqB S SWIM zinc finger
NFMMICNG_00501 1.2e-17
NFMMICNG_00502 2e-116 ywqC M biosynthesis protein
NFMMICNG_00503 5.8e-118 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NFMMICNG_00504 5.1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NFMMICNG_00505 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NFMMICNG_00506 1.4e-152 ywqG S Domain of unknown function (DUF1963)
NFMMICNG_00507 9.7e-23 S Domain of unknown function (DUF5082)
NFMMICNG_00508 8.6e-38 ywqI S Family of unknown function (DUF5344)
NFMMICNG_00509 9.7e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
NFMMICNG_00510 7.9e-43
NFMMICNG_00511 5.2e-17
NFMMICNG_00512 1.9e-82 ywqJ S Pre-toxin TG
NFMMICNG_00513 3.9e-25
NFMMICNG_00514 3.2e-119 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NFMMICNG_00515 1.4e-161 K Transcriptional regulator
NFMMICNG_00516 1.1e-100 ywqN S NAD(P)H-dependent
NFMMICNG_00518 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
NFMMICNG_00519 1.2e-103 ywrB P Chromate transporter
NFMMICNG_00520 8e-82 ywrC K Transcriptional regulator
NFMMICNG_00521 1.4e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NFMMICNG_00522 1.4e-53 S Domain of unknown function (DUF4181)
NFMMICNG_00523 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NFMMICNG_00524 3.7e-12
NFMMICNG_00525 3.5e-210 cotH M Spore Coat
NFMMICNG_00526 2.7e-130 cotB
NFMMICNG_00527 7.5e-126 ywrJ
NFMMICNG_00528 4.6e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NFMMICNG_00529 1.1e-169 alsR K LysR substrate binding domain
NFMMICNG_00530 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NFMMICNG_00531 2.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NFMMICNG_00532 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NFMMICNG_00533 8e-48 ywsA S Protein of unknown function (DUF3892)
NFMMICNG_00534 8.7e-93 batE T Sh3 type 3 domain protein
NFMMICNG_00535 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NFMMICNG_00536 2.1e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
NFMMICNG_00537 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NFMMICNG_00538 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NFMMICNG_00539 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NFMMICNG_00540 9.3e-178 rbsR K transcriptional
NFMMICNG_00541 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NFMMICNG_00542 8.6e-70 pgsC S biosynthesis protein
NFMMICNG_00543 1.1e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NFMMICNG_00544 3.6e-21 ywtC
NFMMICNG_00545 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NFMMICNG_00546 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NFMMICNG_00547 8.4e-171 ywtF K Transcriptional regulator
NFMMICNG_00548 1.9e-248 ywtG EGP Major facilitator Superfamily
NFMMICNG_00549 7.1e-206 gerAC S Spore germination protein
NFMMICNG_00550 1.5e-192 gerBB E Spore germination protein
NFMMICNG_00551 1.2e-261 gerBA EG Spore germination protein
NFMMICNG_00552 5.7e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NFMMICNG_00553 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NFMMICNG_00554 3.5e-260
NFMMICNG_00555 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NFMMICNG_00556 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NFMMICNG_00557 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NFMMICNG_00558 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
NFMMICNG_00559 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NFMMICNG_00560 4.1e-150 tagG GM Transport permease protein
NFMMICNG_00561 9.2e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NFMMICNG_00562 1.9e-36 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NFMMICNG_00563 1.9e-54 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NFMMICNG_00564 3e-39 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NFMMICNG_00565 7.5e-93 ggaA M Glycosyltransferase like family 2
NFMMICNG_00566 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NFMMICNG_00567 6.5e-57
NFMMICNG_00568 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NFMMICNG_00569 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NFMMICNG_00570 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NFMMICNG_00571 6e-38
NFMMICNG_00572 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NFMMICNG_00573 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NFMMICNG_00574 7.8e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NFMMICNG_00575 5.3e-246 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NFMMICNG_00576 7.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NFMMICNG_00577 4.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NFMMICNG_00578 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
NFMMICNG_00579 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
NFMMICNG_00580 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
NFMMICNG_00581 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NFMMICNG_00582 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NFMMICNG_00583 6e-163 yvhJ K Transcriptional regulator
NFMMICNG_00584 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NFMMICNG_00585 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NFMMICNG_00586 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NFMMICNG_00587 7.3e-155 degV S protein conserved in bacteria
NFMMICNG_00588 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NFMMICNG_00589 5.7e-46 comFB S Late competence development protein ComFB
NFMMICNG_00590 2.7e-129 comFC S Phosphoribosyl transferase domain
NFMMICNG_00591 7e-74 yvyF S flagellar protein
NFMMICNG_00592 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
NFMMICNG_00593 2.4e-78 flgN NOU FlgN protein
NFMMICNG_00594 1.2e-264 flgK N flagellar hook-associated protein
NFMMICNG_00595 1.1e-156 flgL N Belongs to the bacterial flagellin family
NFMMICNG_00596 2.6e-50 yviE
NFMMICNG_00597 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NFMMICNG_00598 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NFMMICNG_00599 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NFMMICNG_00600 6.1e-57 flaG N flagellar protein FlaG
NFMMICNG_00601 1.1e-265 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NFMMICNG_00602 2.9e-69 fliS N flagellar protein FliS
NFMMICNG_00603 1.9e-08 fliT S bacterial-type flagellum organization
NFMMICNG_00604 5.4e-65
NFMMICNG_00605 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NFMMICNG_00606 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NFMMICNG_00607 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NFMMICNG_00608 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NFMMICNG_00609 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
NFMMICNG_00610 1.6e-123 ftsE D cell division ATP-binding protein FtsE
NFMMICNG_00611 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NFMMICNG_00612 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NFMMICNG_00613 5.3e-56 swrA S Swarming motility protein
NFMMICNG_00614 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NFMMICNG_00615 7.9e-228 yvkA EGP Major facilitator Superfamily
NFMMICNG_00616 7e-101 yvkB K Transcriptional regulator
NFMMICNG_00617 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NFMMICNG_00618 1.2e-30 csbA S protein conserved in bacteria
NFMMICNG_00619 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NFMMICNG_00620 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NFMMICNG_00621 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NFMMICNG_00622 6.7e-34 yvkN
NFMMICNG_00623 8e-49 yvlA
NFMMICNG_00624 3.4e-168 yvlB S Putative adhesin
NFMMICNG_00625 2.6e-26 pspB KT PspC domain
NFMMICNG_00626 1.2e-50 yvlD S Membrane
NFMMICNG_00627 2.7e-203 yvmA EGP Major facilitator Superfamily
NFMMICNG_00628 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
NFMMICNG_00629 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NFMMICNG_00630 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
NFMMICNG_00631 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
NFMMICNG_00632 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NFMMICNG_00633 8.9e-133 yvoA K transcriptional
NFMMICNG_00634 9.2e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NFMMICNG_00635 3.3e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NFMMICNG_00636 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NFMMICNG_00637 1.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NFMMICNG_00638 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
NFMMICNG_00639 1.2e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NFMMICNG_00640 7.3e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NFMMICNG_00641 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NFMMICNG_00642 3.8e-139 yvpB NU protein conserved in bacteria
NFMMICNG_00643 1.3e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NFMMICNG_00644 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NFMMICNG_00645 5.8e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NFMMICNG_00646 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NFMMICNG_00647 7.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NFMMICNG_00648 5.8e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NFMMICNG_00649 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NFMMICNG_00650 2.6e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NFMMICNG_00651 7.6e-65
NFMMICNG_00652 1.1e-73
NFMMICNG_00653 0.0
NFMMICNG_00655 0.0 msbA2 3.6.3.44 V ABC transporter
NFMMICNG_00656 4.5e-277 S COG0457 FOG TPR repeat
NFMMICNG_00657 1.1e-97 usp CBM50 M protein conserved in bacteria
NFMMICNG_00658 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NFMMICNG_00659 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NFMMICNG_00660 5.7e-166 rapZ S Displays ATPase and GTPase activities
NFMMICNG_00661 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NFMMICNG_00662 1.4e-170 whiA K May be required for sporulation
NFMMICNG_00663 1.6e-36 crh G Phosphocarrier protein Chr
NFMMICNG_00664 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NFMMICNG_00665 1.8e-33
NFMMICNG_00666 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFMMICNG_00667 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NFMMICNG_00668 5.6e-141 yvcR V ABC transporter, ATP-binding protein
NFMMICNG_00669 0.0 yxdM V ABC transporter (permease)
NFMMICNG_00670 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NFMMICNG_00671 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NFMMICNG_00672 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NFMMICNG_00673 2.6e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
NFMMICNG_00674 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NFMMICNG_00675 3.6e-174 yvdE K Transcriptional regulator
NFMMICNG_00676 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NFMMICNG_00677 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NFMMICNG_00678 5.9e-244 malC P COG1175 ABC-type sugar transport systems, permease components
NFMMICNG_00679 3.9e-148 malD P transport
NFMMICNG_00680 5e-154 malA S Protein of unknown function (DUF1189)
NFMMICNG_00681 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NFMMICNG_00682 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NFMMICNG_00683 2.8e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NFMMICNG_00684 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NFMMICNG_00686 2.8e-182 S Patatin-like phospholipase
NFMMICNG_00687 1.1e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
NFMMICNG_00688 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
NFMMICNG_00689 4.1e-50 sugE P Small Multidrug Resistance protein
NFMMICNG_00690 1.9e-50 ykkC P Small Multidrug Resistance protein
NFMMICNG_00691 2.6e-106 yvdT K Transcriptional regulator
NFMMICNG_00692 1.8e-295 yveA E amino acid
NFMMICNG_00693 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NFMMICNG_00694 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NFMMICNG_00695 3.2e-261 pbpE V Beta-lactamase
NFMMICNG_00696 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NFMMICNG_00697 3.8e-73 MA20_18690 S Protein of unknown function (DUF3237)
NFMMICNG_00698 5.1e-92 padC Q Phenolic acid decarboxylase
NFMMICNG_00700 1.6e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NFMMICNG_00701 1.4e-75 slr K transcriptional
NFMMICNG_00702 4e-122 ywqC M biosynthesis protein
NFMMICNG_00703 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NFMMICNG_00704 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NFMMICNG_00705 1.2e-221 epsD GT4 M Glycosyl transferase 4-like
NFMMICNG_00706 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NFMMICNG_00707 8.4e-218 epsF GT4 M Glycosyl transferases group 1
NFMMICNG_00708 7e-206 epsG S EpsG family
NFMMICNG_00709 9.8e-194 epsH GT2 S Glycosyltransferase like family 2
NFMMICNG_00710 1.2e-202 epsI GM pyruvyl transferase
NFMMICNG_00711 2.7e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NFMMICNG_00712 1.4e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NFMMICNG_00713 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NFMMICNG_00714 9e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NFMMICNG_00715 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NFMMICNG_00716 2.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
NFMMICNG_00717 1e-31 yvfG S YvfG protein
NFMMICNG_00718 1.2e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NFMMICNG_00719 2.6e-308 yvfH C L-lactate permease
NFMMICNG_00720 1e-112 yvfI K COG2186 Transcriptional regulators
NFMMICNG_00721 1.8e-184 lacR K Transcriptional regulator
NFMMICNG_00722 4.4e-228 cycB G COG2182 Maltose-binding periplasmic proteins domains
NFMMICNG_00723 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
NFMMICNG_00724 7.2e-150 ganQ P transport
NFMMICNG_00725 0.0 lacA 3.2.1.23 G beta-galactosidase
NFMMICNG_00726 2.3e-248 galA 3.2.1.89 G arabinogalactan
NFMMICNG_00727 3.2e-196 rsbU 3.1.3.3 T response regulator
NFMMICNG_00728 6.4e-156 rsbQ S Alpha/beta hydrolase family
NFMMICNG_00729 1.7e-157 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NFMMICNG_00730 6.9e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
NFMMICNG_00731 1.6e-194 desK 2.7.13.3 T Histidine kinase
NFMMICNG_00732 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NFMMICNG_00733 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NFMMICNG_00734 1.7e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NFMMICNG_00735 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NFMMICNG_00736 2.6e-194 yvbX S Glycosyl hydrolase
NFMMICNG_00737 3.7e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NFMMICNG_00738 7.2e-156 yvbV EG EamA-like transporter family
NFMMICNG_00739 5.1e-159 yvbU K Transcriptional regulator
NFMMICNG_00740 4.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NFMMICNG_00741 5.5e-203 araR K transcriptional
NFMMICNG_00742 1.6e-252 araE EGP Major facilitator Superfamily
NFMMICNG_00743 2.6e-183 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NFMMICNG_00744 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NFMMICNG_00745 3.8e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NFMMICNG_00746 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NFMMICNG_00747 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NFMMICNG_00748 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NFMMICNG_00749 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
NFMMICNG_00750 0.0 tcaA S response to antibiotic
NFMMICNG_00751 1.3e-120 exoY M Membrane
NFMMICNG_00752 8.6e-113 yvbH S YvbH-like oligomerisation region
NFMMICNG_00753 2.7e-101 yvbG U UPF0056 membrane protein
NFMMICNG_00754 3.5e-97 yvbF K Belongs to the GbsR family
NFMMICNG_00755 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NFMMICNG_00756 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NFMMICNG_00757 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NFMMICNG_00758 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NFMMICNG_00759 3.3e-60 yvbF K Belongs to the GbsR family
NFMMICNG_00760 2.8e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NFMMICNG_00761 5.6e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NFMMICNG_00762 8e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NFMMICNG_00763 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NFMMICNG_00764 1.1e-213 NT chemotaxis protein
NFMMICNG_00765 2.2e-54 yodB K transcriptional
NFMMICNG_00766 7.5e-36 yvzC K Transcriptional
NFMMICNG_00767 3.7e-153 yvaM S Serine aminopeptidase, S33
NFMMICNG_00768 2.4e-23 secG U Preprotein translocase subunit SecG
NFMMICNG_00769 5.6e-143 est 3.1.1.1 S Carboxylesterase
NFMMICNG_00770 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NFMMICNG_00771 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NFMMICNG_00773 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NFMMICNG_00774 4.1e-101 K Bacterial regulatory proteins, tetR family
NFMMICNG_00775 6.3e-55 yvaE P Small Multidrug Resistance protein
NFMMICNG_00776 1.3e-72 yvaD S Family of unknown function (DUF5360)
NFMMICNG_00777 0.0 yvaC S Fusaric acid resistance protein-like
NFMMICNG_00778 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NFMMICNG_00779 3.1e-195 yvaA 1.1.1.371 S Oxidoreductase
NFMMICNG_00780 2.2e-48 csoR S transcriptional
NFMMICNG_00781 1.5e-29 copZ P Copper resistance protein CopZ
NFMMICNG_00782 0.0 copA 3.6.3.54 P P-type ATPase
NFMMICNG_00783 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NFMMICNG_00784 1.6e-104 bdbD O Thioredoxin
NFMMICNG_00785 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
NFMMICNG_00786 2.7e-106 yvgT S membrane
NFMMICNG_00788 0.0 helD 3.6.4.12 L DNA helicase
NFMMICNG_00789 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NFMMICNG_00790 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NFMMICNG_00791 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NFMMICNG_00792 2.1e-85 yvgO
NFMMICNG_00793 2.2e-156 yvgN S reductase
NFMMICNG_00794 3.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
NFMMICNG_00795 4.9e-137 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NFMMICNG_00796 1.1e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NFMMICNG_00797 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NFMMICNG_00798 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NFMMICNG_00799 6.5e-16 S Small spore protein J (Spore_SspJ)
NFMMICNG_00800 4.9e-236 yvsH E Arginine ornithine antiporter
NFMMICNG_00802 7.6e-177 fhuD P ABC transporter
NFMMICNG_00803 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFMMICNG_00804 3.4e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFMMICNG_00805 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
NFMMICNG_00806 2.6e-174 M Efflux transporter rnd family, mfp subunit
NFMMICNG_00807 2.1e-123 macB V ABC transporter, ATP-binding protein
NFMMICNG_00808 3.4e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NFMMICNG_00809 3.8e-64 yvrL S Regulatory protein YrvL
NFMMICNG_00810 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
NFMMICNG_00811 2.4e-19 S YvrJ protein family
NFMMICNG_00812 9.5e-98 yvrI K RNA polymerase
NFMMICNG_00813 3.6e-22
NFMMICNG_00814 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFMMICNG_00815 0.0 T PhoQ Sensor
NFMMICNG_00816 2.9e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
NFMMICNG_00817 2.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NFMMICNG_00818 1.9e-167 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NFMMICNG_00819 1.6e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFMMICNG_00820 1.1e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NFMMICNG_00821 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
NFMMICNG_00822 1.4e-226 yvqJ EGP Major facilitator Superfamily
NFMMICNG_00823 5.6e-62 liaI S membrane
NFMMICNG_00824 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NFMMICNG_00825 2.3e-127 liaG S Putative adhesin
NFMMICNG_00826 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NFMMICNG_00827 3.5e-186 vraS 2.7.13.3 T Histidine kinase
NFMMICNG_00828 8.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NFMMICNG_00829 3.3e-187 gerAC S Spore germination B3/ GerAC like, C-terminal
NFMMICNG_00830 9.1e-198 gerAB E Spore germination protein
NFMMICNG_00831 1.4e-246 gerAA EG Spore germination protein
NFMMICNG_00832 2.3e-24 S Protein of unknown function (DUF3970)
NFMMICNG_00833 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NFMMICNG_00834 4.3e-158 yuxN K Transcriptional regulator
NFMMICNG_00835 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
NFMMICNG_00836 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFMMICNG_00837 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NFMMICNG_00838 1.2e-79 dps P Ferritin-like domain
NFMMICNG_00839 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NFMMICNG_00840 1.9e-301 pepF2 E COG1164 Oligoendopeptidase F
NFMMICNG_00841 2.5e-66 S YusW-like protein
NFMMICNG_00842 1e-153 yusV 3.6.3.34 HP ABC transporter
NFMMICNG_00843 3.8e-47 yusU S Protein of unknown function (DUF2573)
NFMMICNG_00844 5.7e-158 yusT K LysR substrate binding domain
NFMMICNG_00845 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NFMMICNG_00846 2.7e-64 yusQ S Tautomerase enzyme
NFMMICNG_00847 3.2e-292 yusP P Major facilitator superfamily
NFMMICNG_00848 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
NFMMICNG_00849 5.4e-53 yusN M Coat F domain
NFMMICNG_00850 5.1e-40
NFMMICNG_00851 7.1e-164 fadM E Proline dehydrogenase
NFMMICNG_00852 8.1e-09 S YuzL-like protein
NFMMICNG_00853 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NFMMICNG_00854 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
NFMMICNG_00855 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NFMMICNG_00856 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NFMMICNG_00857 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NFMMICNG_00858 1.1e-39 yusG S Protein of unknown function (DUF2553)
NFMMICNG_00859 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NFMMICNG_00860 5.6e-55 traF CO Thioredoxin
NFMMICNG_00861 2.4e-56 yusD S SCP-2 sterol transfer family
NFMMICNG_00862 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NFMMICNG_00863 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NFMMICNG_00864 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
NFMMICNG_00865 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NFMMICNG_00866 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NFMMICNG_00867 9.1e-245 sufD O assembly protein SufD
NFMMICNG_00868 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NFMMICNG_00869 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NFMMICNG_00870 3.5e-271 sufB O FeS cluster assembly
NFMMICNG_00871 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFMMICNG_00872 1e-41
NFMMICNG_00874 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NFMMICNG_00875 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NFMMICNG_00876 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NFMMICNG_00877 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NFMMICNG_00878 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
NFMMICNG_00879 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
NFMMICNG_00880 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NFMMICNG_00881 1.1e-135 yurK K UTRA
NFMMICNG_00882 1.2e-205 msmX P Belongs to the ABC transporter superfamily
NFMMICNG_00883 2.4e-169 bsn L Ribonuclease
NFMMICNG_00884 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NFMMICNG_00885 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NFMMICNG_00887 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NFMMICNG_00888 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NFMMICNG_00889 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NFMMICNG_00890 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NFMMICNG_00891 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NFMMICNG_00892 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NFMMICNG_00893 7.3e-283 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NFMMICNG_00894 1.3e-222 pbuX F xanthine
NFMMICNG_00895 2.1e-236 pbuX F Permease family
NFMMICNG_00896 3.4e-302 pucR QT COG2508 Regulator of polyketide synthase expression
NFMMICNG_00897 7.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NFMMICNG_00898 6.7e-62 yunG
NFMMICNG_00899 7.3e-171 yunF S Protein of unknown function DUF72
NFMMICNG_00900 1e-140 yunE S membrane transporter protein
NFMMICNG_00901 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NFMMICNG_00902 5.3e-47 yunC S Domain of unknown function (DUF1805)
NFMMICNG_00903 4.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
NFMMICNG_00904 3.8e-195 lytH M Peptidase, M23
NFMMICNG_00905 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NFMMICNG_00906 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NFMMICNG_00907 9.7e-48 yutD S protein conserved in bacteria
NFMMICNG_00908 8.6e-75 yutE S Protein of unknown function DUF86
NFMMICNG_00909 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NFMMICNG_00910 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NFMMICNG_00911 2.9e-198 yutH S Spore coat protein
NFMMICNG_00912 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
NFMMICNG_00913 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NFMMICNG_00914 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NFMMICNG_00915 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NFMMICNG_00916 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NFMMICNG_00917 3.5e-57 yuzD S protein conserved in bacteria
NFMMICNG_00918 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NFMMICNG_00919 3.2e-39 yuzB S Belongs to the UPF0349 family
NFMMICNG_00920 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NFMMICNG_00921 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NFMMICNG_00922 3.7e-63 erpA S Belongs to the HesB IscA family
NFMMICNG_00923 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NFMMICNG_00924 1e-116 paiB K Putative FMN-binding domain
NFMMICNG_00925 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NFMMICNG_00927 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
NFMMICNG_00928 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
NFMMICNG_00929 8.4e-27 yuiB S Putative membrane protein
NFMMICNG_00930 5.6e-118 yuiC S protein conserved in bacteria
NFMMICNG_00931 1.2e-77 yuiD S protein conserved in bacteria
NFMMICNG_00932 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NFMMICNG_00933 3.9e-211 yuiF S antiporter
NFMMICNG_00934 4.4e-93 bioY S Biotin biosynthesis protein
NFMMICNG_00935 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
NFMMICNG_00936 1.3e-167 besA S Putative esterase
NFMMICNG_00937 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NFMMICNG_00938 6.6e-226 entC 5.4.4.2 HQ Isochorismate synthase
NFMMICNG_00939 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NFMMICNG_00940 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NFMMICNG_00941 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFMMICNG_00942 3.8e-36 mbtH S MbtH-like protein
NFMMICNG_00943 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NFMMICNG_00944 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NFMMICNG_00945 6.5e-229 yukF QT Transcriptional regulator
NFMMICNG_00946 2.8e-45 esxA S Belongs to the WXG100 family
NFMMICNG_00947 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NFMMICNG_00948 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
NFMMICNG_00949 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NFMMICNG_00950 0.0 esaA S type VII secretion protein EsaA
NFMMICNG_00951 6.6e-65 yueC S Family of unknown function (DUF5383)
NFMMICNG_00952 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFMMICNG_00953 4.8e-96 yueE S phosphohydrolase
NFMMICNG_00954 2.9e-24 S Protein of unknown function (DUF2642)
NFMMICNG_00955 6.1e-72 S Protein of unknown function (DUF2283)
NFMMICNG_00956 1.9e-190 yueF S transporter activity
NFMMICNG_00957 2.1e-32 yueG S Spore germination protein gerPA/gerPF
NFMMICNG_00958 2.8e-38 yueH S YueH-like protein
NFMMICNG_00959 7.9e-67 yueI S Protein of unknown function (DUF1694)
NFMMICNG_00960 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
NFMMICNG_00961 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NFMMICNG_00962 1.8e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NFMMICNG_00963 3.2e-22 yuzC
NFMMICNG_00966 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
NFMMICNG_00968 0.0 comP 2.7.13.3 T Histidine kinase
NFMMICNG_00969 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NFMMICNG_00970 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
NFMMICNG_00971 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NFMMICNG_00972 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NFMMICNG_00973 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NFMMICNG_00974 6.4e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NFMMICNG_00975 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NFMMICNG_00976 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NFMMICNG_00977 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NFMMICNG_00978 3.2e-14
NFMMICNG_00979 1.3e-233 maeN C COG3493 Na citrate symporter
NFMMICNG_00980 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
NFMMICNG_00981 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
NFMMICNG_00982 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NFMMICNG_00983 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NFMMICNG_00984 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
NFMMICNG_00985 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NFMMICNG_00986 6.3e-78 yufK S Family of unknown function (DUF5366)
NFMMICNG_00987 1.8e-74 yuxK S protein conserved in bacteria
NFMMICNG_00988 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NFMMICNG_00989 3.8e-185 yuxJ EGP Major facilitator Superfamily
NFMMICNG_00991 1.9e-115 kapD L the KinA pathway to sporulation
NFMMICNG_00992 3.1e-68 kapB G Kinase associated protein B
NFMMICNG_00993 4.6e-233 T PhoQ Sensor
NFMMICNG_00994 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NFMMICNG_00995 1.6e-39 yugE S Domain of unknown function (DUF1871)
NFMMICNG_00996 4.9e-156 yugF I Hydrolase
NFMMICNG_00997 1.6e-85 alaR K Transcriptional regulator
NFMMICNG_00998 2.1e-199 yugH 2.6.1.1 E Aminotransferase
NFMMICNG_00999 1.5e-62 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NFMMICNG_01000 3.1e-34 yuzA S Domain of unknown function (DUF378)
NFMMICNG_01001 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NFMMICNG_01002 2.8e-229 yugK C Dehydrogenase
NFMMICNG_01003 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NFMMICNG_01005 1.3e-72 yugN S YugN-like family
NFMMICNG_01006 2.2e-182 yugO P COG1226 Kef-type K transport systems
NFMMICNG_01007 1.1e-53 mstX S Membrane-integrating protein Mistic
NFMMICNG_01008 2.3e-38
NFMMICNG_01009 1.4e-116 yugP S Zn-dependent protease
NFMMICNG_01010 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NFMMICNG_01011 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NFMMICNG_01012 1.8e-71 yugU S Uncharacterised protein family UPF0047
NFMMICNG_01013 2.3e-35
NFMMICNG_01014 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NFMMICNG_01015 3.2e-225 mcpA NT chemotaxis protein
NFMMICNG_01016 2.4e-220 mcpA NT chemotaxis protein
NFMMICNG_01017 4.7e-293 mcpA NT chemotaxis protein
NFMMICNG_01018 7.3e-238 mcpA NT chemotaxis protein
NFMMICNG_01019 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NFMMICNG_01020 6.6e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NFMMICNG_01021 5.1e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NFMMICNG_01022 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NFMMICNG_01023 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NFMMICNG_01024 3.3e-183 ygjR S Oxidoreductase
NFMMICNG_01025 1.3e-194 yubA S transporter activity
NFMMICNG_01026 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NFMMICNG_01028 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NFMMICNG_01029 2.4e-273 yubD P Major Facilitator Superfamily
NFMMICNG_01030 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NFMMICNG_01031 1e-38 yiaA S yiaA/B two helix domain
NFMMICNG_01032 1.6e-236 ktrB P Potassium
NFMMICNG_01033 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
NFMMICNG_01034 2.2e-91 yuaB
NFMMICNG_01035 2.7e-94 yuaC K Belongs to the GbsR family
NFMMICNG_01036 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NFMMICNG_01037 1.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
NFMMICNG_01038 7.4e-106 yuaD
NFMMICNG_01039 3.9e-84 yuaE S DinB superfamily
NFMMICNG_01040 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NFMMICNG_01041 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
NFMMICNG_01042 1.4e-92 M1-753 M FR47-like protein
NFMMICNG_01043 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
NFMMICNG_01048 2e-08
NFMMICNG_01055 1.3e-09
NFMMICNG_01056 7.8e-08
NFMMICNG_01065 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NFMMICNG_01066 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NFMMICNG_01067 6.4e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NFMMICNG_01068 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NFMMICNG_01069 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NFMMICNG_01070 9.9e-77 tspO T membrane
NFMMICNG_01071 1.8e-206 cotI S Spore coat protein
NFMMICNG_01072 1.8e-217 cotSA M Glycosyl transferases group 1
NFMMICNG_01073 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
NFMMICNG_01075 3.6e-235 ytcC M Glycosyltransferase Family 4
NFMMICNG_01076 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NFMMICNG_01077 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NFMMICNG_01078 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
NFMMICNG_01079 2.6e-132 dksA T COG1734 DnaK suppressor protein
NFMMICNG_01080 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
NFMMICNG_01081 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NFMMICNG_01082 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NFMMICNG_01083 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NFMMICNG_01084 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NFMMICNG_01085 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NFMMICNG_01086 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
NFMMICNG_01087 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NFMMICNG_01088 8.8e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NFMMICNG_01089 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NFMMICNG_01090 1.1e-24 S Domain of Unknown Function (DUF1540)
NFMMICNG_01091 1.8e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NFMMICNG_01092 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
NFMMICNG_01093 3.6e-41 rpmE2 J Ribosomal protein L31
NFMMICNG_01094 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NFMMICNG_01095 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NFMMICNG_01096 2.4e-72 ytkA S YtkA-like
NFMMICNG_01098 2.1e-76 dps P Belongs to the Dps family
NFMMICNG_01099 5.4e-63 ytkC S Bacteriophage holin family
NFMMICNG_01100 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NFMMICNG_01101 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NFMMICNG_01102 1.4e-144 ytlC P ABC transporter
NFMMICNG_01103 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NFMMICNG_01104 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NFMMICNG_01105 1.2e-38 ytmB S Protein of unknown function (DUF2584)
NFMMICNG_01106 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NFMMICNG_01107 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NFMMICNG_01108 0.0 asnB 6.3.5.4 E Asparagine synthase
NFMMICNG_01109 1.1e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NFMMICNG_01110 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NFMMICNG_01111 5.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
NFMMICNG_01112 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NFMMICNG_01113 3.3e-106 ytqB J Putative rRNA methylase
NFMMICNG_01114 2.1e-190 yhcC S Fe-S oxidoreductase
NFMMICNG_01115 6.7e-41 ytzC S Protein of unknown function (DUF2524)
NFMMICNG_01117 5.1e-66 ytrA K GntR family transcriptional regulator
NFMMICNG_01118 4.2e-161 ytrB P abc transporter atp-binding protein
NFMMICNG_01119 8.3e-166 P ABC-2 family transporter protein
NFMMICNG_01120 5.9e-148
NFMMICNG_01121 3.1e-127 ytrE V ABC transporter, ATP-binding protein
NFMMICNG_01122 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NFMMICNG_01123 1.1e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFMMICNG_01124 1.5e-183 T PhoQ Sensor
NFMMICNG_01125 1.1e-138 bceA V ABC transporter, ATP-binding protein
NFMMICNG_01126 0.0 bceB V ABC transporter (permease)
NFMMICNG_01127 1.3e-41 yttA 2.7.13.3 S Pfam Transposase IS66
NFMMICNG_01128 7.3e-209 yttB EGP Major facilitator Superfamily
NFMMICNG_01129 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NFMMICNG_01130 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NFMMICNG_01131 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NFMMICNG_01132 2.1e-51 ytwF P Sulfurtransferase
NFMMICNG_01133 5.8e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NFMMICNG_01134 1.1e-142 amyC P ABC transporter (permease)
NFMMICNG_01135 1.4e-167 amyD P ABC transporter
NFMMICNG_01136 1.9e-247 msmE G Bacterial extracellular solute-binding protein
NFMMICNG_01137 1.5e-189 msmR K Transcriptional regulator
NFMMICNG_01138 7.8e-171 ytaP S Acetyl xylan esterase (AXE1)
NFMMICNG_01139 3.1e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NFMMICNG_01140 3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NFMMICNG_01141 1.8e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NFMMICNG_01142 1.9e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NFMMICNG_01143 5.4e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NFMMICNG_01144 1.7e-221 bioI 1.14.14.46 C Cytochrome P450
NFMMICNG_01145 1.2e-135 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NFMMICNG_01146 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
NFMMICNG_01147 1.8e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NFMMICNG_01148 0.0 ytdP K Transcriptional regulator
NFMMICNG_01149 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NFMMICNG_01150 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NFMMICNG_01151 4.6e-73 yteS G transport
NFMMICNG_01152 2.6e-249 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NFMMICNG_01153 4.8e-117 yteU S Integral membrane protein
NFMMICNG_01154 3.1e-26 yteV S Sporulation protein Cse60
NFMMICNG_01155 7.5e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NFMMICNG_01156 1.4e-231 ytfP S HI0933-like protein
NFMMICNG_01157 3.6e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NFMMICNG_01158 1.8e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NFMMICNG_01159 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NFMMICNG_01160 9e-130 ythP V ABC transporter
NFMMICNG_01161 1.5e-203 ythQ U Bacterial ABC transporter protein EcsB
NFMMICNG_01162 7.2e-226 pbuO S permease
NFMMICNG_01163 7.1e-272 pepV 3.5.1.18 E Dipeptidase
NFMMICNG_01164 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NFMMICNG_01165 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NFMMICNG_01166 1.3e-165 ytlQ
NFMMICNG_01167 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NFMMICNG_01168 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NFMMICNG_01169 1e-150 ytmP 2.7.1.89 M Phosphotransferase
NFMMICNG_01170 2e-45 ytzH S YtzH-like protein
NFMMICNG_01171 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NFMMICNG_01172 1.8e-148 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NFMMICNG_01173 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NFMMICNG_01174 2.2e-51 ytzB S small secreted protein
NFMMICNG_01175 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NFMMICNG_01176 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NFMMICNG_01177 4.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NFMMICNG_01178 9.8e-149 ytpQ S Belongs to the UPF0354 family
NFMMICNG_01179 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NFMMICNG_01180 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NFMMICNG_01181 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NFMMICNG_01182 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NFMMICNG_01183 6.6e-17 ytxH S COG4980 Gas vesicle protein
NFMMICNG_01184 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
NFMMICNG_01185 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NFMMICNG_01186 3.8e-182 ccpA K catabolite control protein A
NFMMICNG_01187 2.1e-146 motA N flagellar motor
NFMMICNG_01188 1.4e-125 motS N Flagellar motor protein
NFMMICNG_01189 1.6e-224 acuC BQ histone deacetylase
NFMMICNG_01190 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
NFMMICNG_01191 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NFMMICNG_01192 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NFMMICNG_01193 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NFMMICNG_01195 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NFMMICNG_01196 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NFMMICNG_01197 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NFMMICNG_01198 3.4e-109 yttP K Transcriptional regulator
NFMMICNG_01199 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NFMMICNG_01200 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NFMMICNG_01201 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
NFMMICNG_01202 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
NFMMICNG_01203 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NFMMICNG_01204 2e-29 sspB S spore protein
NFMMICNG_01205 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NFMMICNG_01206 0.0 ytcJ S amidohydrolase
NFMMICNG_01207 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NFMMICNG_01208 7.1e-181 sppA OU signal peptide peptidase SppA
NFMMICNG_01209 1.3e-87 yteJ S RDD family
NFMMICNG_01210 5.6e-116 ytfI S Protein of unknown function (DUF2953)
NFMMICNG_01211 8.7e-70 ytfJ S Sporulation protein YtfJ
NFMMICNG_01212 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NFMMICNG_01213 7e-165 ytxK 2.1.1.72 L DNA methylase
NFMMICNG_01214 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NFMMICNG_01215 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NFMMICNG_01216 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NFMMICNG_01217 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
NFMMICNG_01219 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFMMICNG_01220 1.7e-130 ytkL S Belongs to the UPF0173 family
NFMMICNG_01221 2.9e-173 ytlI K LysR substrate binding domain
NFMMICNG_01222 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
NFMMICNG_01223 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
NFMMICNG_01224 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
NFMMICNG_01225 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
NFMMICNG_01226 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
NFMMICNG_01227 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NFMMICNG_01228 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NFMMICNG_01229 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
NFMMICNG_01230 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NFMMICNG_01231 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
NFMMICNG_01232 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
NFMMICNG_01233 1.2e-158 ytnM S membrane transporter protein
NFMMICNG_01234 8e-241 ytoI K transcriptional regulator containing CBS domains
NFMMICNG_01235 2.4e-47 ytpI S YtpI-like protein
NFMMICNG_01236 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NFMMICNG_01237 9.2e-29
NFMMICNG_01238 2.4e-68 ytrI
NFMMICNG_01239 3.2e-56 ytrH S Sporulation protein YtrH
NFMMICNG_01240 0.0 dnaE 2.7.7.7 L DNA polymerase
NFMMICNG_01241 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NFMMICNG_01242 3.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NFMMICNG_01243 8.1e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NFMMICNG_01244 7.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NFMMICNG_01245 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NFMMICNG_01246 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NFMMICNG_01247 9.9e-192 ytvI S sporulation integral membrane protein YtvI
NFMMICNG_01248 4.7e-71 yeaL S membrane
NFMMICNG_01249 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NFMMICNG_01250 1.8e-242 icd 1.1.1.42 C isocitrate
NFMMICNG_01251 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NFMMICNG_01252 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFMMICNG_01253 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NFMMICNG_01254 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NFMMICNG_01255 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NFMMICNG_01256 1.1e-107 ytaF P Probably functions as a manganese efflux pump
NFMMICNG_01257 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NFMMICNG_01258 8.9e-161 ytbE S reductase
NFMMICNG_01259 4.9e-205 ytbD EGP Major facilitator Superfamily
NFMMICNG_01260 9.9e-67 ytcD K Transcriptional regulator
NFMMICNG_01261 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NFMMICNG_01262 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NFMMICNG_01263 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NFMMICNG_01264 3.5e-266 dnaB L Membrane attachment protein
NFMMICNG_01265 3e-173 dnaI L Primosomal protein DnaI
NFMMICNG_01266 4.9e-111 ytxB S SNARE associated Golgi protein
NFMMICNG_01267 3.8e-159 ytxC S YtxC-like family
NFMMICNG_01268 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NFMMICNG_01269 1.5e-149 ysaA S HAD-hyrolase-like
NFMMICNG_01270 0.0 lytS 2.7.13.3 T Histidine kinase
NFMMICNG_01271 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
NFMMICNG_01272 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NFMMICNG_01273 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NFMMICNG_01275 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NFMMICNG_01276 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NFMMICNG_01277 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NFMMICNG_01278 7.5e-45 ysdA S Membrane
NFMMICNG_01279 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NFMMICNG_01280 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
NFMMICNG_01281 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NFMMICNG_01282 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NFMMICNG_01283 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NFMMICNG_01284 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NFMMICNG_01285 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NFMMICNG_01286 1.8e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NFMMICNG_01287 2e-252 araN G carbohydrate transport
NFMMICNG_01288 4.2e-167 araP G carbohydrate transport
NFMMICNG_01289 3.8e-143 araQ G transport system permease
NFMMICNG_01290 1.7e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NFMMICNG_01291 0.0 cstA T Carbon starvation protein
NFMMICNG_01292 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
NFMMICNG_01293 5.8e-255 glcF C Glycolate oxidase
NFMMICNG_01294 8.2e-260 glcD 1.1.3.15 C Glycolate oxidase subunit
NFMMICNG_01295 9.2e-206 ysfB KT regulator
NFMMICNG_01296 5.8e-32 sspI S Belongs to the SspI family
NFMMICNG_01297 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NFMMICNG_01298 2.3e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NFMMICNG_01299 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NFMMICNG_01300 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NFMMICNG_01301 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NFMMICNG_01302 1.3e-85 cvpA S membrane protein, required for colicin V production
NFMMICNG_01303 0.0 polX L COG1796 DNA polymerase IV (family X)
NFMMICNG_01304 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NFMMICNG_01305 7.3e-68 yshE S membrane
NFMMICNG_01306 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NFMMICNG_01307 2.7e-100 fadR K Transcriptional regulator
NFMMICNG_01308 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NFMMICNG_01309 4.5e-135 etfB C Electron transfer flavoprotein
NFMMICNG_01310 2.1e-177 etfA C Electron transfer flavoprotein
NFMMICNG_01312 5.7e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NFMMICNG_01313 2e-52 trxA O Belongs to the thioredoxin family
NFMMICNG_01314 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NFMMICNG_01315 3.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NFMMICNG_01316 1.2e-79 yslB S Protein of unknown function (DUF2507)
NFMMICNG_01317 2.4e-107 sdhC C succinate dehydrogenase
NFMMICNG_01318 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NFMMICNG_01319 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NFMMICNG_01320 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NFMMICNG_01321 3.3e-30 gerE K Transcriptional regulator
NFMMICNG_01322 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NFMMICNG_01323 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NFMMICNG_01324 2.9e-196 gerM S COG5401 Spore germination protein
NFMMICNG_01325 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NFMMICNG_01326 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NFMMICNG_01327 1.4e-92 ysnB S Phosphoesterase
NFMMICNG_01329 9.1e-134 ysnF S protein conserved in bacteria
NFMMICNG_01330 7.6e-82 ysnE K acetyltransferase
NFMMICNG_01332 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NFMMICNG_01333 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
NFMMICNG_01334 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NFMMICNG_01335 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NFMMICNG_01336 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NFMMICNG_01337 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NFMMICNG_01338 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NFMMICNG_01339 2.3e-187 ysoA H Tetratricopeptide repeat
NFMMICNG_01340 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NFMMICNG_01341 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NFMMICNG_01342 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NFMMICNG_01343 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NFMMICNG_01344 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NFMMICNG_01345 1.4e-89 ysxD
NFMMICNG_01346 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NFMMICNG_01347 3.6e-146 hemX O cytochrome C
NFMMICNG_01348 9.6e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NFMMICNG_01349 7.1e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NFMMICNG_01350 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
NFMMICNG_01351 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NFMMICNG_01352 2.2e-222 spoVID M stage VI sporulation protein D
NFMMICNG_01353 1.7e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NFMMICNG_01354 1.6e-25
NFMMICNG_01355 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NFMMICNG_01356 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NFMMICNG_01357 8.3e-126 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NFMMICNG_01358 8.4e-166 spoIIB S Sporulation related domain
NFMMICNG_01359 8.3e-102 maf D septum formation protein Maf
NFMMICNG_01360 1.3e-125 radC E Belongs to the UPF0758 family
NFMMICNG_01361 1.8e-184 mreB D Rod shape-determining protein MreB
NFMMICNG_01362 2.8e-157 mreC M Involved in formation and maintenance of cell shape
NFMMICNG_01363 1.4e-84 mreD M shape-determining protein
NFMMICNG_01364 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NFMMICNG_01365 4.7e-143 minD D Belongs to the ParA family
NFMMICNG_01366 9.3e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NFMMICNG_01367 9.2e-161 spoIVFB S Stage IV sporulation protein
NFMMICNG_01368 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NFMMICNG_01369 4.1e-56 ysxB J ribosomal protein
NFMMICNG_01370 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NFMMICNG_01371 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NFMMICNG_01372 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NFMMICNG_01373 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NFMMICNG_01374 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
NFMMICNG_01375 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
NFMMICNG_01376 4.5e-227 nifS 2.8.1.7 E Cysteine desulfurase
NFMMICNG_01377 2.3e-303 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NFMMICNG_01378 1.9e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NFMMICNG_01379 1.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NFMMICNG_01380 8.3e-157 safA M spore coat assembly protein SafA
NFMMICNG_01381 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NFMMICNG_01382 1e-125 yebC K transcriptional regulatory protein
NFMMICNG_01383 4.5e-261 alsT E Sodium alanine symporter
NFMMICNG_01384 1.3e-50 S Family of unknown function (DUF5412)
NFMMICNG_01386 6.5e-119 yrzF T serine threonine protein kinase
NFMMICNG_01387 4.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NFMMICNG_01388 4.5e-252 csbX EGP Major facilitator Superfamily
NFMMICNG_01389 4.8e-93 bofC S BofC C-terminal domain
NFMMICNG_01390 3.8e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NFMMICNG_01391 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NFMMICNG_01392 2.6e-18 yrzS S Protein of unknown function (DUF2905)
NFMMICNG_01393 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NFMMICNG_01394 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NFMMICNG_01395 1.1e-38 yajC U Preprotein translocase subunit YajC
NFMMICNG_01396 2.2e-73 yrzE S Protein of unknown function (DUF3792)
NFMMICNG_01397 3e-111 yrbG S membrane
NFMMICNG_01398 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NFMMICNG_01399 9.4e-49 yrzD S Post-transcriptional regulator
NFMMICNG_01400 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NFMMICNG_01401 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NFMMICNG_01402 3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NFMMICNG_01403 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NFMMICNG_01404 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NFMMICNG_01405 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NFMMICNG_01406 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NFMMICNG_01407 1.5e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
NFMMICNG_01409 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NFMMICNG_01410 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NFMMICNG_01411 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NFMMICNG_01412 4.4e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NFMMICNG_01413 1.2e-70 cymR K Transcriptional regulator
NFMMICNG_01414 1.4e-212 iscS 2.8.1.7 E Cysteine desulfurase
NFMMICNG_01415 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NFMMICNG_01416 1.4e-15 S COG0457 FOG TPR repeat
NFMMICNG_01417 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NFMMICNG_01418 2.5e-80 yrrD S protein conserved in bacteria
NFMMICNG_01419 9.8e-31 yrzR
NFMMICNG_01420 8e-08 S Protein of unknown function (DUF3918)
NFMMICNG_01421 7.6e-107 glnP P ABC transporter
NFMMICNG_01422 8e-109 gluC P ABC transporter
NFMMICNG_01423 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
NFMMICNG_01424 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NFMMICNG_01425 2.7e-170 yrrI S AI-2E family transporter
NFMMICNG_01426 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NFMMICNG_01427 1.7e-41 yrzL S Belongs to the UPF0297 family
NFMMICNG_01428 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NFMMICNG_01429 1.2e-45 yrzB S Belongs to the UPF0473 family
NFMMICNG_01430 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NFMMICNG_01431 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
NFMMICNG_01432 3.9e-173 yegQ O Peptidase U32
NFMMICNG_01433 2.7e-246 yegQ O COG0826 Collagenase and related proteases
NFMMICNG_01434 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NFMMICNG_01435 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NFMMICNG_01436 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NFMMICNG_01437 2.5e-60 yrrS S Protein of unknown function (DUF1510)
NFMMICNG_01438 1e-25 yrzA S Protein of unknown function (DUF2536)
NFMMICNG_01439 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NFMMICNG_01440 1.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NFMMICNG_01441 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NFMMICNG_01442 1.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NFMMICNG_01443 4.6e-35 yrhC S YrhC-like protein
NFMMICNG_01444 1.4e-78 yrhD S Protein of unknown function (DUF1641)
NFMMICNG_01445 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NFMMICNG_01446 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
NFMMICNG_01447 1.8e-142 focA P Formate nitrite
NFMMICNG_01450 7.2e-95 yrhH Q methyltransferase
NFMMICNG_01451 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NFMMICNG_01452 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NFMMICNG_01453 4.3e-168 capL C PFAM UDP-glucose GDP-mannose dehydrogenase
NFMMICNG_01454 2.6e-119 wbpP 5.1.3.2, 5.1.3.7 GM NmrA-like family
NFMMICNG_01455 9.4e-117 S ATPases associated with a variety of cellular activities
NFMMICNG_01456 5.7e-64 S ABC-2 family transporter protein
NFMMICNG_01457 8.3e-63 S ABC-2 family transporter protein
NFMMICNG_01458 7.2e-104 Q TIGRFAM amino acid adenylation domain
NFMMICNG_01459 2e-46 hopR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NFMMICNG_01460 1.5e-180 hutH 4.3.1.23, 4.3.1.24, 4.3.1.3, 5.4.3.6 E Aromatic amino acid lyase
NFMMICNG_01461 1.2e-100 EF ATP-grasp domain
NFMMICNG_01462 6.6e-88 yodQ 3.5.1.16 E Acetylornithine deacetylase
NFMMICNG_01463 1.5e-52 S dehydrogenases and related proteins
NFMMICNG_01464 3.9e-11 O Butirosin biosynthesis protein H, N-terminal
NFMMICNG_01465 7.3e-29 S Butirosin biosynthesis protein H, N-terminal
NFMMICNG_01466 1e-18 yrhK S YrhK-like protein
NFMMICNG_01467 0.0 yrhL I Acyltransferase family
NFMMICNG_01468 3.8e-151 rsiV S Protein of unknown function (DUF3298)
NFMMICNG_01469 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NFMMICNG_01470 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
NFMMICNG_01471 3.6e-106 yrhP E LysE type translocator
NFMMICNG_01472 1e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NFMMICNG_01473 0.0 levR K PTS system fructose IIA component
NFMMICNG_01474 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
NFMMICNG_01475 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NFMMICNG_01476 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NFMMICNG_01477 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NFMMICNG_01478 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NFMMICNG_01479 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
NFMMICNG_01480 3.2e-200 adhA 1.1.1.1 C alcohol dehydrogenase
NFMMICNG_01481 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
NFMMICNG_01482 4.3e-47 yraB K helix_turn_helix, mercury resistance
NFMMICNG_01483 1.1e-49 yraD M Spore coat protein
NFMMICNG_01484 2.6e-26 yraE
NFMMICNG_01485 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NFMMICNG_01486 6.4e-63 yraF M Spore coat protein
NFMMICNG_01487 5.3e-37 yraG
NFMMICNG_01488 1.3e-66 E Glyoxalase-like domain
NFMMICNG_01489 2.4e-61 T sh3 domain protein
NFMMICNG_01490 1.7e-60 T sh3 domain protein
NFMMICNG_01491 3.2e-155 S Alpha beta hydrolase
NFMMICNG_01492 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NFMMICNG_01493 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NFMMICNG_01495 1.6e-205 yraM S PrpF protein
NFMMICNG_01496 3.4e-163 yraN K Transcriptional regulator
NFMMICNG_01497 3.4e-223 yraO C Citrate transporter
NFMMICNG_01498 1.3e-187 yrpG C Aldo/keto reductase family
NFMMICNG_01499 2.4e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NFMMICNG_01500 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NFMMICNG_01502 1.6e-123 yrpD S Domain of unknown function, YrpD
NFMMICNG_01503 4.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NFMMICNG_01504 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NFMMICNG_01505 4.2e-166 aadK G Streptomycin adenylyltransferase
NFMMICNG_01506 2.4e-89 yrdA S DinB family
NFMMICNG_01507 3.3e-57 S Protein of unknown function (DUF2568)
NFMMICNG_01508 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
NFMMICNG_01509 1.1e-40 yrdF K ribonuclease inhibitor
NFMMICNG_01510 5.3e-78 bkdR K helix_turn_helix ASNC type
NFMMICNG_01511 9.6e-138 azlC E AzlC protein
NFMMICNG_01512 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NFMMICNG_01513 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
NFMMICNG_01514 5e-162 gltR K LysR substrate binding domain
NFMMICNG_01515 1.3e-66 yodA S tautomerase
NFMMICNG_01516 4e-149 czcD P COG1230 Co Zn Cd efflux system component
NFMMICNG_01517 2.3e-198 trkA P Oxidoreductase
NFMMICNG_01518 3e-159 yrdQ K Transcriptional regulator
NFMMICNG_01519 1.6e-169 yrdR EG EamA-like transporter family
NFMMICNG_01520 3.9e-16 S YrzO-like protein
NFMMICNG_01521 2.5e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NFMMICNG_01522 5.9e-82 bltD 2.3.1.57 K FR47-like protein
NFMMICNG_01523 3.9e-210 blt EGP Major facilitator Superfamily
NFMMICNG_01524 4.2e-147 bltR K helix_turn_helix, mercury resistance
NFMMICNG_01525 5.5e-106 yrkC G Cupin domain
NFMMICNG_01526 7.8e-39 yrkD S protein conserved in bacteria
NFMMICNG_01527 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
NFMMICNG_01528 2.3e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
NFMMICNG_01529 9.3e-206 yrkH P Rhodanese Homology Domain
NFMMICNG_01530 3.5e-35 yrkI O Belongs to the sulfur carrier protein TusA family
NFMMICNG_01531 5.4e-112 yrkJ S membrane transporter protein
NFMMICNG_01532 7e-166 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NFMMICNG_01533 2e-215 mepA V Multidrug transporter MatE
NFMMICNG_01534 3.6e-112 tetR3 K Transcriptional regulator
NFMMICNG_01535 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFMMICNG_01536 1.2e-94 yqaB E IrrE N-terminal-like domain
NFMMICNG_01538 1.2e-97 adk 2.7.4.3 F adenylate kinase activity
NFMMICNG_01540 1.1e-32 K sequence-specific DNA binding
NFMMICNG_01541 1.2e-17 K Helix-turn-helix XRE-family like proteins
NFMMICNG_01543 1.2e-103
NFMMICNG_01547 1.4e-162 yqaJ L YqaJ-like viral recombinase domain
NFMMICNG_01548 2.5e-155 recT L RecT family
NFMMICNG_01549 1e-122 3.1.3.16 L DnaD domain protein
NFMMICNG_01550 5.9e-168 xkdC L IstB-like ATP binding protein
NFMMICNG_01552 7.2e-74 rusA L Endodeoxyribonuclease RusA
NFMMICNG_01553 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
NFMMICNG_01554 1.6e-166
NFMMICNG_01555 6.5e-81 L Transposase
NFMMICNG_01557 6.3e-107 yqaS L DNA packaging
NFMMICNG_01558 2.4e-253 S phage terminase, large subunit
NFMMICNG_01559 3.3e-286 yqbA S portal protein
NFMMICNG_01560 1.4e-151 S Phage Mu protein F like protein
NFMMICNG_01561 6.1e-63
NFMMICNG_01562 2.8e-118 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NFMMICNG_01563 7.1e-167 xkdG S Phage capsid family
NFMMICNG_01564 1.6e-46 S YqbF, hypothetical protein domain
NFMMICNG_01565 3.9e-66 S Protein of unknown function (DUF3199)
NFMMICNG_01566 1.2e-61 yqbH S Domain of unknown function (DUF3599)
NFMMICNG_01567 3.3e-86 S Bacteriophage HK97-gp10, putative tail-component
NFMMICNG_01568 7.8e-76
NFMMICNG_01569 1.8e-24
NFMMICNG_01570 6.3e-252 xkdK S Phage tail sheath C-terminal domain
NFMMICNG_01571 3.6e-76 xkdM S Phage tail tube protein
NFMMICNG_01572 1.2e-66 S Phage XkdN-like tail assembly chaperone protein, TAC
NFMMICNG_01573 0.0 xkdO L Transglycosylase SLT domain
NFMMICNG_01574 7.6e-113 xkdP S Lysin motif
NFMMICNG_01575 4.2e-178 yqbQ 3.2.1.96 G NLP P60 protein
NFMMICNG_01576 2.7e-31 xkdR S Protein of unknown function (DUF2577)
NFMMICNG_01577 1.9e-66 xkdS S Protein of unknown function (DUF2634)
NFMMICNG_01578 5.5e-184 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NFMMICNG_01579 7.1e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NFMMICNG_01580 9.6e-40
NFMMICNG_01581 4.2e-219
NFMMICNG_01582 4.1e-56 xkdW S XkdW protein
NFMMICNG_01583 3.7e-10
NFMMICNG_01584 3e-159 xepA
NFMMICNG_01585 2.6e-68 S Bacteriophage holin family
NFMMICNG_01586 5.9e-133 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NFMMICNG_01589 4.6e-100 S Suppressor of fused protein (SUFU)
NFMMICNG_01590 3.7e-47
NFMMICNG_01591 1.3e-14 S SMI1-KNR4 cell-wall
NFMMICNG_01593 1.1e-26 yokK S SMI1 / KNR4 family
NFMMICNG_01594 6e-228 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NFMMICNG_01595 1e-70 K MerR family transcriptional regulator
NFMMICNG_01596 1.3e-138 yvgN 1.1.1.346 S Reductase
NFMMICNG_01597 8.4e-130 S Aspartate phosphatase response regulator
NFMMICNG_01599 1.3e-123 yecA E amino acid
NFMMICNG_01600 1.5e-105 K Transcriptional regulator
NFMMICNG_01601 4.6e-277 cisA2 L Recombinase
NFMMICNG_01602 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFMMICNG_01603 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
NFMMICNG_01604 2e-132 yqeB
NFMMICNG_01605 1.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NFMMICNG_01606 2.3e-105 yqeD S SNARE associated Golgi protein
NFMMICNG_01607 1.7e-131 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NFMMICNG_01608 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
NFMMICNG_01610 5.3e-95 yqeG S hydrolase of the HAD superfamily
NFMMICNG_01611 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NFMMICNG_01612 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NFMMICNG_01613 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NFMMICNG_01614 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NFMMICNG_01615 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NFMMICNG_01616 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NFMMICNG_01617 2.9e-139 yqeM Q Methyltransferase
NFMMICNG_01618 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NFMMICNG_01619 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NFMMICNG_01620 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
NFMMICNG_01621 0.0 comEC S Competence protein ComEC
NFMMICNG_01622 4.1e-15 S YqzM-like protein
NFMMICNG_01623 5.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
NFMMICNG_01624 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NFMMICNG_01625 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NFMMICNG_01626 4.5e-222 spoIIP M stage II sporulation protein P
NFMMICNG_01627 7.2e-53 yqxA S Protein of unknown function (DUF3679)
NFMMICNG_01628 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NFMMICNG_01629 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
NFMMICNG_01630 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NFMMICNG_01631 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NFMMICNG_01632 0.0 dnaK O Heat shock 70 kDa protein
NFMMICNG_01633 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NFMMICNG_01634 6e-174 prmA J Methylates ribosomal protein L11
NFMMICNG_01635 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NFMMICNG_01636 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NFMMICNG_01637 8.2e-158 yqeW P COG1283 Na phosphate symporter
NFMMICNG_01638 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NFMMICNG_01639 2.5e-61 yqeY S Yqey-like protein
NFMMICNG_01640 7.7e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NFMMICNG_01641 4.3e-122 yqfA S UPF0365 protein
NFMMICNG_01642 2.4e-21 yqfB
NFMMICNG_01643 2.7e-45 yqfC S sporulation protein YqfC
NFMMICNG_01644 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NFMMICNG_01645 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
NFMMICNG_01647 0.0 yqfF S membrane-associated HD superfamily hydrolase
NFMMICNG_01648 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NFMMICNG_01649 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NFMMICNG_01650 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NFMMICNG_01651 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NFMMICNG_01652 8.4e-19 S YqzL-like protein
NFMMICNG_01653 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
NFMMICNG_01654 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NFMMICNG_01655 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NFMMICNG_01656 4.5e-112 ccpN K CBS domain
NFMMICNG_01657 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NFMMICNG_01658 4.5e-88 yaiI S Belongs to the UPF0178 family
NFMMICNG_01659 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NFMMICNG_01660 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NFMMICNG_01661 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NFMMICNG_01662 1.5e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
NFMMICNG_01663 5.3e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NFMMICNG_01664 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NFMMICNG_01665 3.5e-12 yqfQ S YqfQ-like protein
NFMMICNG_01666 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NFMMICNG_01667 2.6e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NFMMICNG_01668 7.9e-36 yqfT S Protein of unknown function (DUF2624)
NFMMICNG_01669 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NFMMICNG_01670 1.9e-77 zur P Belongs to the Fur family
NFMMICNG_01671 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NFMMICNG_01672 4.3e-62 yqfX S membrane
NFMMICNG_01673 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NFMMICNG_01674 5.2e-47 yqfZ M LysM domain
NFMMICNG_01675 3.9e-131 yqgB S Protein of unknown function (DUF1189)
NFMMICNG_01676 4e-73 yqgC S protein conserved in bacteria
NFMMICNG_01677 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NFMMICNG_01678 2.5e-231 yqgE EGP Major facilitator superfamily
NFMMICNG_01679 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NFMMICNG_01680 3.4e-150 pstS P Phosphate
NFMMICNG_01681 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NFMMICNG_01682 4.4e-158 pstA P Phosphate transport system permease
NFMMICNG_01683 3.2e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NFMMICNG_01684 8.3e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NFMMICNG_01685 2.1e-71 yqzC S YceG-like family
NFMMICNG_01686 3.5e-50 yqzD
NFMMICNG_01688 1.5e-41 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NFMMICNG_01689 4.1e-133 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NFMMICNG_01690 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NFMMICNG_01691 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NFMMICNG_01692 2.5e-09 yqgO
NFMMICNG_01693 4e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NFMMICNG_01694 3.1e-33 yqgQ S Protein conserved in bacteria
NFMMICNG_01695 5.2e-181 glcK 2.7.1.2 G Glucokinase
NFMMICNG_01696 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NFMMICNG_01697 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NFMMICNG_01698 2.7e-199 yqgU
NFMMICNG_01699 6.9e-50 yqgV S Thiamine-binding protein
NFMMICNG_01700 8.9e-23 yqgW S Protein of unknown function (DUF2759)
NFMMICNG_01701 9.5e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NFMMICNG_01702 1.8e-37 yqgY S Protein of unknown function (DUF2626)
NFMMICNG_01703 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NFMMICNG_01705 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NFMMICNG_01706 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NFMMICNG_01707 1.4e-173 corA P Mg2 transporter protein
NFMMICNG_01710 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NFMMICNG_01711 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
NFMMICNG_01712 6.8e-47 comGC U Required for transformation and DNA binding
NFMMICNG_01713 6.3e-70 gspH NU protein transport across the cell outer membrane
NFMMICNG_01714 2e-58 comGE
NFMMICNG_01715 1.7e-34 comGF U Putative Competence protein ComGF
NFMMICNG_01716 8.8e-44 S ComG operon protein 7
NFMMICNG_01717 4.4e-25 yqzE S YqzE-like protein
NFMMICNG_01718 7.3e-54 yqzG S Protein of unknown function (DUF3889)
NFMMICNG_01719 2.8e-113 yqxM
NFMMICNG_01720 2.5e-58 sipW 3.4.21.89 U Signal peptidase
NFMMICNG_01721 1.9e-141 tasA S Cell division protein FtsN
NFMMICNG_01722 1e-54 sinR K transcriptional
NFMMICNG_01723 1.2e-24 sinI S Anti-repressor SinI
NFMMICNG_01724 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
NFMMICNG_01725 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NFMMICNG_01726 1.8e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NFMMICNG_01727 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NFMMICNG_01728 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NFMMICNG_01729 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
NFMMICNG_01730 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NFMMICNG_01731 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NFMMICNG_01732 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
NFMMICNG_01733 2.2e-61 yqhP
NFMMICNG_01734 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
NFMMICNG_01735 2.3e-93 yqhR S Conserved membrane protein YqhR
NFMMICNG_01736 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NFMMICNG_01737 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NFMMICNG_01738 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NFMMICNG_01739 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NFMMICNG_01740 1e-170 spoIIIAA S stage III sporulation protein AA
NFMMICNG_01741 1.1e-84 spoIIIAB S Stage III sporulation protein
NFMMICNG_01742 7.6e-29 spoIIIAC S stage III sporulation protein AC
NFMMICNG_01743 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NFMMICNG_01744 2.9e-197 spoIIIAE S stage III sporulation protein AE
NFMMICNG_01745 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NFMMICNG_01746 6.5e-109 spoIIIAG S stage III sporulation protein AG
NFMMICNG_01747 9.9e-91 spoIIIAH S SpoIIIAH-like protein
NFMMICNG_01748 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NFMMICNG_01749 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NFMMICNG_01750 2.1e-67 yqhY S protein conserved in bacteria
NFMMICNG_01751 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NFMMICNG_01752 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NFMMICNG_01753 1.1e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NFMMICNG_01754 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NFMMICNG_01755 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NFMMICNG_01756 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NFMMICNG_01757 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NFMMICNG_01758 1.7e-78 argR K Regulates arginine biosynthesis genes
NFMMICNG_01759 0.0 recN L May be involved in recombinational repair of damaged DNA
NFMMICNG_01760 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
NFMMICNG_01761 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NFMMICNG_01763 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NFMMICNG_01764 5.9e-27
NFMMICNG_01765 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NFMMICNG_01766 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NFMMICNG_01767 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
NFMMICNG_01768 2.3e-156 hbdA 1.1.1.157 I Dehydrogenase
NFMMICNG_01769 8.8e-212 mmgC I acyl-CoA dehydrogenase
NFMMICNG_01770 8.4e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NFMMICNG_01771 2.4e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NFMMICNG_01772 6.9e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NFMMICNG_01773 4e-34 yqzF S Protein of unknown function (DUF2627)
NFMMICNG_01774 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NFMMICNG_01775 2.3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NFMMICNG_01776 1.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NFMMICNG_01777 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NFMMICNG_01778 2.8e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NFMMICNG_01779 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NFMMICNG_01780 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NFMMICNG_01781 5.4e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NFMMICNG_01782 6.4e-151 bmrR K helix_turn_helix, mercury resistance
NFMMICNG_01783 5.1e-207 norA EGP Major facilitator Superfamily
NFMMICNG_01784 9.8e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NFMMICNG_01785 9.3e-77 yqiW S Belongs to the UPF0403 family
NFMMICNG_01786 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
NFMMICNG_01787 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NFMMICNG_01788 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NFMMICNG_01789 7.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
NFMMICNG_01790 1.4e-98 yqjB S protein conserved in bacteria
NFMMICNG_01792 8.7e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NFMMICNG_01793 3.8e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NFMMICNG_01794 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NFMMICNG_01795 2.6e-140 yqjF S Uncharacterized conserved protein (COG2071)
NFMMICNG_01796 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NFMMICNG_01797 4.5e-24 yqzJ
NFMMICNG_01798 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NFMMICNG_01799 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NFMMICNG_01800 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NFMMICNG_01801 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NFMMICNG_01802 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NFMMICNG_01803 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NFMMICNG_01804 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NFMMICNG_01805 0.0 rocB E arginine degradation protein
NFMMICNG_01806 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NFMMICNG_01807 4.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NFMMICNG_01808 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NFMMICNG_01809 9.3e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NFMMICNG_01810 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
NFMMICNG_01811 4.7e-08 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFMMICNG_01812 1.1e-42 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFMMICNG_01814 6.1e-222 yqjV G Major Facilitator Superfamily
NFMMICNG_01816 9.2e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NFMMICNG_01817 2.2e-49 S YolD-like protein
NFMMICNG_01818 1.8e-86 yqjY K acetyltransferase
NFMMICNG_01819 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NFMMICNG_01820 7.5e-194 yqkA K GrpB protein
NFMMICNG_01821 2.8e-54 yqkB S Belongs to the HesB IscA family
NFMMICNG_01822 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NFMMICNG_01823 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NFMMICNG_01824 3.1e-12 yqkE S Protein of unknown function (DUF3886)
NFMMICNG_01825 4.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NFMMICNG_01827 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NFMMICNG_01828 1.4e-220 yqxK 3.6.4.12 L DNA helicase
NFMMICNG_01829 4.5e-58 ansR K Transcriptional regulator
NFMMICNG_01830 2.3e-184 ansA 3.5.1.1 EJ L-asparaginase
NFMMICNG_01831 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NFMMICNG_01832 2.7e-234 mleN C Na H antiporter
NFMMICNG_01833 5.5e-242 mleA 1.1.1.38 C malic enzyme
NFMMICNG_01834 5.5e-30 yqkK
NFMMICNG_01835 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NFMMICNG_01836 2.4e-80 fur P Belongs to the Fur family
NFMMICNG_01837 3.7e-37 S Protein of unknown function (DUF4227)
NFMMICNG_01838 2.6e-166 xerD L recombinase XerD
NFMMICNG_01839 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NFMMICNG_01840 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NFMMICNG_01841 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NFMMICNG_01842 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NFMMICNG_01843 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NFMMICNG_01844 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFMMICNG_01845 7.4e-112 spoVAA S Stage V sporulation protein AA
NFMMICNG_01846 1e-67 spoVAB S Stage V sporulation protein AB
NFMMICNG_01847 2.3e-78 spoVAC S stage V sporulation protein AC
NFMMICNG_01848 9e-192 spoVAD I Stage V sporulation protein AD
NFMMICNG_01849 2.2e-57 spoVAEB S stage V sporulation protein
NFMMICNG_01850 1.4e-110 spoVAEA S stage V sporulation protein
NFMMICNG_01851 1.4e-273 spoVAF EG Stage V sporulation protein AF
NFMMICNG_01852 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NFMMICNG_01853 3.6e-149 ypuA S Secreted protein
NFMMICNG_01854 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NFMMICNG_01857 3.4e-13 S PAP2 superfamily
NFMMICNG_01858 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NFMMICNG_01859 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NFMMICNG_01860 7.8e-55 ypuD
NFMMICNG_01861 2.4e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NFMMICNG_01862 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
NFMMICNG_01863 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NFMMICNG_01864 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NFMMICNG_01865 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NFMMICNG_01866 1.4e-92 ypuF S Domain of unknown function (DUF309)
NFMMICNG_01867 2.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NFMMICNG_01868 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NFMMICNG_01869 7.6e-97 ypuI S Protein of unknown function (DUF3907)
NFMMICNG_01870 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NFMMICNG_01871 3.5e-103 spmA S Spore maturation protein
NFMMICNG_01872 1.9e-87 spmB S Spore maturation protein
NFMMICNG_01873 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NFMMICNG_01874 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NFMMICNG_01875 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NFMMICNG_01876 9.7e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NFMMICNG_01877 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFMMICNG_01878 0.0 resE 2.7.13.3 T Histidine kinase
NFMMICNG_01879 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NFMMICNG_01880 7.3e-195 rsiX
NFMMICNG_01881 2.2e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NFMMICNG_01882 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NFMMICNG_01883 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NFMMICNG_01884 4.7e-41 fer C Ferredoxin
NFMMICNG_01885 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
NFMMICNG_01886 3.2e-286 recQ 3.6.4.12 L DNA helicase
NFMMICNG_01887 2.2e-100 ypbD S metal-dependent membrane protease
NFMMICNG_01888 4.6e-81 ypbE M Lysin motif
NFMMICNG_01889 2.8e-81 ypbF S Protein of unknown function (DUF2663)
NFMMICNG_01890 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
NFMMICNG_01891 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NFMMICNG_01892 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NFMMICNG_01893 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NFMMICNG_01894 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
NFMMICNG_01895 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NFMMICNG_01896 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NFMMICNG_01897 9.2e-113 ypfA M Flagellar protein YcgR
NFMMICNG_01898 1.8e-23 S Family of unknown function (DUF5359)
NFMMICNG_01899 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NFMMICNG_01900 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
NFMMICNG_01901 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NFMMICNG_01902 1e-07 S YpzI-like protein
NFMMICNG_01903 1.3e-102 yphA
NFMMICNG_01904 2.5e-161 seaA S YIEGIA protein
NFMMICNG_01905 1.6e-28 ypzH
NFMMICNG_01906 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NFMMICNG_01907 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NFMMICNG_01908 1.6e-18 yphE S Protein of unknown function (DUF2768)
NFMMICNG_01909 5.4e-138 yphF
NFMMICNG_01910 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NFMMICNG_01911 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NFMMICNG_01912 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NFMMICNG_01913 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NFMMICNG_01914 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NFMMICNG_01915 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NFMMICNG_01916 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NFMMICNG_01917 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NFMMICNG_01918 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NFMMICNG_01919 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NFMMICNG_01920 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NFMMICNG_01921 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NFMMICNG_01922 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NFMMICNG_01923 3.9e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NFMMICNG_01924 8.1e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NFMMICNG_01925 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NFMMICNG_01926 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NFMMICNG_01927 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NFMMICNG_01928 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NFMMICNG_01929 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NFMMICNG_01930 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NFMMICNG_01931 4.1e-234 S COG0457 FOG TPR repeat
NFMMICNG_01932 1.1e-98 ypiB S Belongs to the UPF0302 family
NFMMICNG_01933 4.2e-77 ypiF S Protein of unknown function (DUF2487)
NFMMICNG_01934 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NFMMICNG_01935 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NFMMICNG_01936 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NFMMICNG_01937 7.6e-98 ypjA S membrane
NFMMICNG_01938 1e-142 ypjB S sporulation protein
NFMMICNG_01939 5.2e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NFMMICNG_01940 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NFMMICNG_01941 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NFMMICNG_01942 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NFMMICNG_01943 1.7e-128 bshB1 S proteins, LmbE homologs
NFMMICNG_01944 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NFMMICNG_01945 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NFMMICNG_01946 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NFMMICNG_01947 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NFMMICNG_01948 6.1e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NFMMICNG_01949 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NFMMICNG_01950 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NFMMICNG_01951 1.9e-22 ypmA S Protein of unknown function (DUF4264)
NFMMICNG_01952 4.9e-79 ypmB S protein conserved in bacteria
NFMMICNG_01953 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NFMMICNG_01954 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NFMMICNG_01955 1.3e-128 dnaD L DNA replication protein DnaD
NFMMICNG_01956 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NFMMICNG_01957 1.8e-92 ypoC
NFMMICNG_01958 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NFMMICNG_01959 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NFMMICNG_01960 5.4e-186 yppC S Protein of unknown function (DUF2515)
NFMMICNG_01963 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
NFMMICNG_01965 6.6e-47 yppG S YppG-like protein
NFMMICNG_01966 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
NFMMICNG_01967 1.2e-80 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NFMMICNG_01968 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NFMMICNG_01969 2.5e-236 yprB L RNase_H superfamily
NFMMICNG_01970 8.2e-91 ypsA S Belongs to the UPF0398 family
NFMMICNG_01971 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NFMMICNG_01972 1.2e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NFMMICNG_01974 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NFMMICNG_01975 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFMMICNG_01976 1.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NFMMICNG_01977 7.4e-186 ptxS K transcriptional
NFMMICNG_01978 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NFMMICNG_01979 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NFMMICNG_01980 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NFMMICNG_01981 3.9e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NFMMICNG_01982 4.4e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NFMMICNG_01983 3.8e-227 pbuX F xanthine
NFMMICNG_01984 8.2e-207 bcsA Q Naringenin-chalcone synthase
NFMMICNG_01985 7.4e-86 ypbQ S protein conserved in bacteria
NFMMICNG_01987 0.0 ypbR S Dynamin family
NFMMICNG_01988 8.5e-38 ypbS S Protein of unknown function (DUF2533)
NFMMICNG_01989 2e-07
NFMMICNG_01990 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
NFMMICNG_01992 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
NFMMICNG_01993 4.5e-106 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NFMMICNG_01994 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NFMMICNG_01995 2.6e-27 ypeQ S Zinc-finger
NFMMICNG_01996 1.8e-30 S Protein of unknown function (DUF2564)
NFMMICNG_01997 3.8e-16 degR
NFMMICNG_01998 7.9e-31 cspD K Cold-shock protein
NFMMICNG_01999 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NFMMICNG_02000 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NFMMICNG_02001 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NFMMICNG_02002 5.4e-107 ypgQ S phosphohydrolase
NFMMICNG_02003 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
NFMMICNG_02004 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NFMMICNG_02005 1.7e-75 yphP S Belongs to the UPF0403 family
NFMMICNG_02006 3.7e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NFMMICNG_02007 7.8e-114 ypjP S YpjP-like protein
NFMMICNG_02008 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NFMMICNG_02009 1.5e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NFMMICNG_02010 1.6e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NFMMICNG_02011 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NFMMICNG_02012 4.2e-110 hlyIII S protein, Hemolysin III
NFMMICNG_02013 1.6e-185 pspF K Transcriptional regulator
NFMMICNG_02014 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NFMMICNG_02015 3.1e-40 ypmP S Protein of unknown function (DUF2535)
NFMMICNG_02016 2.7e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NFMMICNG_02017 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
NFMMICNG_02018 1.1e-98 ypmS S protein conserved in bacteria
NFMMICNG_02019 5.5e-29 ypmT S Uncharacterized ympT
NFMMICNG_02020 3.8e-222 mepA V MATE efflux family protein
NFMMICNG_02021 1.6e-70 ypoP K transcriptional
NFMMICNG_02022 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NFMMICNG_02023 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NFMMICNG_02024 1.3e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
NFMMICNG_02025 5.2e-212 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NFMMICNG_02026 2e-185 cgeB S Spore maturation protein
NFMMICNG_02027 1.2e-65 cgeA
NFMMICNG_02028 3.5e-38 cgeC
NFMMICNG_02029 1e-256 cgeD M maturation of the outermost layer of the spore
NFMMICNG_02030 8.3e-145 yiiD K acetyltransferase
NFMMICNG_02032 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NFMMICNG_02033 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NFMMICNG_02034 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NFMMICNG_02035 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
NFMMICNG_02036 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NFMMICNG_02037 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
NFMMICNG_02038 2.9e-47 yokU S YokU-like protein, putative antitoxin
NFMMICNG_02039 1.4e-36 yozE S Belongs to the UPF0346 family
NFMMICNG_02040 1.4e-124 yodN
NFMMICNG_02042 2.8e-24 yozD S YozD-like protein
NFMMICNG_02043 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
NFMMICNG_02044 3.6e-54 yodL S YodL-like
NFMMICNG_02045 5.3e-09
NFMMICNG_02046 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NFMMICNG_02047 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NFMMICNG_02048 5.2e-24 yodI
NFMMICNG_02049 1.7e-128 yodH Q Methyltransferase
NFMMICNG_02050 1.6e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NFMMICNG_02051 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NFMMICNG_02052 6.2e-28 S Protein of unknown function (DUF3311)
NFMMICNG_02053 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
NFMMICNG_02054 3.8e-113 mhqD S Carboxylesterase
NFMMICNG_02055 4.8e-108 yodC C nitroreductase
NFMMICNG_02056 1.7e-57 yodB K transcriptional
NFMMICNG_02057 3.8e-66 yodA S tautomerase
NFMMICNG_02058 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
NFMMICNG_02059 3.4e-09
NFMMICNG_02060 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
NFMMICNG_02061 6.6e-162 rarD S -transporter
NFMMICNG_02062 1.5e-43
NFMMICNG_02063 2.2e-60 yojF S Protein of unknown function (DUF1806)
NFMMICNG_02064 2.1e-125 yojG S deacetylase
NFMMICNG_02065 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NFMMICNG_02066 4.2e-245 norM V Multidrug efflux pump
NFMMICNG_02068 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NFMMICNG_02069 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NFMMICNG_02070 4.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NFMMICNG_02071 4.8e-90 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NFMMICNG_02072 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
NFMMICNG_02073 0.0 yojO P Von Willebrand factor
NFMMICNG_02074 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NFMMICNG_02075 3.5e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NFMMICNG_02076 8.6e-168 yocS S -transporter
NFMMICNG_02077 9.9e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NFMMICNG_02078 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
NFMMICNG_02079 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NFMMICNG_02080 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NFMMICNG_02081 2.7e-31 yozC
NFMMICNG_02082 4.2e-56 yozO S Bacterial PH domain
NFMMICNG_02083 1.9e-36 yocN
NFMMICNG_02084 1.1e-40 yozN
NFMMICNG_02085 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
NFMMICNG_02086 6.6e-34
NFMMICNG_02087 6.4e-54 yocL
NFMMICNG_02088 3.3e-83 dksA T general stress protein
NFMMICNG_02089 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NFMMICNG_02090 0.0 recQ 3.6.4.12 L DNA helicase
NFMMICNG_02091 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
NFMMICNG_02092 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NFMMICNG_02093 1.7e-196 desK 2.7.13.3 T Histidine kinase
NFMMICNG_02094 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NFMMICNG_02095 1.5e-188 yocD 3.4.17.13 V peptidase S66
NFMMICNG_02096 1.2e-93 yocC
NFMMICNG_02097 1.3e-142
NFMMICNG_02098 1.5e-92 yozB S membrane
NFMMICNG_02099 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NFMMICNG_02100 1e-51 czrA K transcriptional
NFMMICNG_02101 1.8e-90 yobW
NFMMICNG_02102 6.2e-171 yobV K WYL domain
NFMMICNG_02103 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
NFMMICNG_02104 2.8e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NFMMICNG_02105 1.3e-97 yobS K Transcriptional regulator
NFMMICNG_02106 5.3e-141 yobR 2.3.1.1 J FR47-like protein
NFMMICNG_02107 3.8e-136 yobQ K helix_turn_helix, arabinose operon control protein
NFMMICNG_02108 1.4e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NFMMICNG_02109 0.0 yobO M Pectate lyase superfamily protein
NFMMICNG_02110 4.4e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NFMMICNG_02111 9.1e-101 yokH G SMI1 / KNR4 family
NFMMICNG_02112 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NFMMICNG_02113 2.8e-84 S SMI1-KNR4 cell-wall
NFMMICNG_02115 2.9e-272 kdpA 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NFMMICNG_02116 0.0 kdpB 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NFMMICNG_02117 1.2e-63 kdpC 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NFMMICNG_02118 2.7e-176 T PhoQ Sensor
NFMMICNG_02120 1.7e-40
NFMMICNG_02122 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NFMMICNG_02123 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NFMMICNG_02126 3.8e-165 bla 3.5.2.6 V beta-lactamase
NFMMICNG_02127 4.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NFMMICNG_02128 1.8e-77 yoaW
NFMMICNG_02129 1.5e-158 yijE EG EamA-like transporter family
NFMMICNG_02130 8.6e-159 yoaU K LysR substrate binding domain
NFMMICNG_02131 5.3e-147 yoaT S Protein of unknown function (DUF817)
NFMMICNG_02132 4.4e-30 yozG K Transcriptional regulator
NFMMICNG_02133 2.8e-74 yoaS S Protein of unknown function (DUF2975)
NFMMICNG_02134 9.3e-172 yoaR V vancomycin resistance protein
NFMMICNG_02135 7.3e-86
NFMMICNG_02138 7.9e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
NFMMICNG_02140 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
NFMMICNG_02141 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NFMMICNG_02142 2.3e-111 yoaK S Membrane
NFMMICNG_02143 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NFMMICNG_02144 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NFMMICNG_02145 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
NFMMICNG_02146 1.5e-38 S Protein of unknown function (DUF4025)
NFMMICNG_02147 2.2e-07
NFMMICNG_02148 3.3e-90 purR K Transcriptional regulator
NFMMICNG_02149 3.2e-151 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
NFMMICNG_02150 1.6e-205 S Oxidoreductase family, C-terminal alpha/beta domain
NFMMICNG_02151 3e-172 iolT EGP Major facilitator Superfamily
NFMMICNG_02152 6.6e-32 yoaF
NFMMICNG_02153 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NFMMICNG_02154 3.8e-99 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NFMMICNG_02155 1.7e-70 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NFMMICNG_02156 5.3e-278 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NFMMICNG_02157 1.2e-233 yoaB EGP Major facilitator Superfamily
NFMMICNG_02158 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
NFMMICNG_02159 1.8e-138 V AAA domain, putative AbiEii toxin, Type IV TA system
NFMMICNG_02160 2.9e-94 V ABC-2 family transporter protein
NFMMICNG_02161 3.8e-126 V ABC-2 family transporter protein
NFMMICNG_02162 5.6e-92 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NFMMICNG_02163 2.5e-130 yoxB
NFMMICNG_02164 7e-39 yoxC S Bacterial protein of unknown function (DUF948)
NFMMICNG_02165 7.7e-121 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NFMMICNG_02166 2e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NFMMICNG_02167 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NFMMICNG_02168 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NFMMICNG_02169 3.9e-154 gltC K Transcriptional regulator
NFMMICNG_02170 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NFMMICNG_02171 6.6e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NFMMICNG_02172 8e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NFMMICNG_02173 2.3e-156 gltR1 K Transcriptional regulator
NFMMICNG_02174 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NFMMICNG_02175 3e-34 yoeD G Helix-turn-helix domain
NFMMICNG_02176 2.2e-96 L Integrase
NFMMICNG_02178 2.6e-97 yoeB S IseA DL-endopeptidase inhibitor
NFMMICNG_02179 2.3e-246 yoeA V MATE efflux family protein
NFMMICNG_02180 5.6e-191 yoxA 5.1.3.3 G Aldose 1-epimerase
NFMMICNG_02181 1.4e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NFMMICNG_02182 9.1e-95 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFMMICNG_02183 3.3e-166 ygxA S Nucleotidyltransferase-like
NFMMICNG_02184 1.1e-54 ygzB S UPF0295 protein
NFMMICNG_02185 4e-80 perR P Belongs to the Fur family
NFMMICNG_02186 6.3e-87 bcp 1.11.1.15 O Peroxiredoxin
NFMMICNG_02187 1.2e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NFMMICNG_02188 8.7e-180 ygaE S Membrane
NFMMICNG_02189 1.8e-301 ygaD V ABC transporter
NFMMICNG_02190 1.3e-104 ygaC J Belongs to the UPF0374 family
NFMMICNG_02191 1.5e-37 ygaB S YgaB-like protein
NFMMICNG_02192 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NFMMICNG_02193 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFMMICNG_02194 6.9e-36 yfhS
NFMMICNG_02195 3.3e-210 mutY L A G-specific
NFMMICNG_02196 1.2e-185 yfhP S membrane-bound metal-dependent
NFMMICNG_02197 0.0 yfhO S Bacterial membrane protein YfhO
NFMMICNG_02198 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NFMMICNG_02199 1.3e-170 yfhM S Alpha beta hydrolase
NFMMICNG_02200 3.5e-51 yfhL S SdpI/YhfL protein family
NFMMICNG_02201 2.4e-87 batE T Bacterial SH3 domain homologues
NFMMICNG_02202 2.9e-44 yfhJ S WVELL protein
NFMMICNG_02203 6.2e-20 sspK S reproduction
NFMMICNG_02204 1.1e-209 yfhI EGP Major facilitator Superfamily
NFMMICNG_02206 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NFMMICNG_02207 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NFMMICNG_02208 1.6e-171 yfhF S nucleoside-diphosphate sugar epimerase
NFMMICNG_02210 2.1e-25 yfhD S YfhD-like protein
NFMMICNG_02211 1.5e-106 yfhC C nitroreductase
NFMMICNG_02212 1.8e-167 yfhB 5.3.3.17 S PhzF family
NFMMICNG_02213 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFMMICNG_02214 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFMMICNG_02215 1e-176 yfiY P ABC transporter substrate-binding protein
NFMMICNG_02216 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NFMMICNG_02217 5.8e-80 yfiV K transcriptional
NFMMICNG_02218 3.4e-283 yfiU EGP Major facilitator Superfamily
NFMMICNG_02219 3.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
NFMMICNG_02220 1.5e-209 yfiS EGP Major facilitator Superfamily
NFMMICNG_02221 7.1e-107 yfiR K Transcriptional regulator
NFMMICNG_02222 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NFMMICNG_02223 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NFMMICNG_02224 8.3e-99 padR K transcriptional
NFMMICNG_02225 2.6e-203 V COG0842 ABC-type multidrug transport system, permease component
NFMMICNG_02226 2e-206 V ABC-2 family transporter protein
NFMMICNG_02227 1.4e-170 V ABC transporter, ATP-binding protein
NFMMICNG_02228 3.2e-113 KT LuxR family transcriptional regulator
NFMMICNG_02229 1.1e-214 yxjM T Histidine kinase
NFMMICNG_02231 1.1e-233 S Oxidoreductase
NFMMICNG_02232 8.4e-184 G Xylose isomerase
NFMMICNG_02233 1.8e-262 iolT EGP Major facilitator Superfamily
NFMMICNG_02234 1.5e-177 K AraC-like ligand binding domain
NFMMICNG_02235 5.7e-163 yfiE 1.13.11.2 S glyoxalase
NFMMICNG_02236 6.4e-64 mhqP S DoxX
NFMMICNG_02237 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NFMMICNG_02238 8.4e-307 yfiB3 V ABC transporter
NFMMICNG_02239 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NFMMICNG_02240 1.6e-140 glvR K Helix-turn-helix domain, rpiR family
NFMMICNG_02241 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NFMMICNG_02242 7.4e-44 yfjA S Belongs to the WXG100 family
NFMMICNG_02243 9.2e-191 yfjB
NFMMICNG_02244 4.5e-143 yfjC
NFMMICNG_02245 1.8e-101 yfjD S Family of unknown function (DUF5381)
NFMMICNG_02246 1.1e-79 S Family of unknown function (DUF5381)
NFMMICNG_02247 4e-56 yfjF S UPF0060 membrane protein
NFMMICNG_02248 8.3e-24 sspH S Belongs to the SspH family
NFMMICNG_02249 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NFMMICNG_02250 2.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NFMMICNG_02251 6.7e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NFMMICNG_02252 7.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NFMMICNG_02253 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NFMMICNG_02254 1.1e-83 yfjM S Psort location Cytoplasmic, score
NFMMICNG_02255 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NFMMICNG_02256 1.6e-39 S YfzA-like protein
NFMMICNG_02257 4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NFMMICNG_02258 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NFMMICNG_02259 1.7e-184 corA P Mediates influx of magnesium ions
NFMMICNG_02260 9.8e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NFMMICNG_02261 1.7e-153 pdaA G deacetylase
NFMMICNG_02262 1.1e-26 yfjT
NFMMICNG_02263 5.4e-222 yfkA S YfkB-like domain
NFMMICNG_02264 6e-149 yfkC M Mechanosensitive ion channel
NFMMICNG_02265 1.2e-146 yfkD S YfkD-like protein
NFMMICNG_02266 1.8e-182 cax P COG0387 Ca2 H antiporter
NFMMICNG_02267 2.6e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NFMMICNG_02268 5e-08
NFMMICNG_02269 4.8e-143 yihY S Belongs to the UPF0761 family
NFMMICNG_02270 1.2e-49 yfkI S gas vesicle protein
NFMMICNG_02271 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NFMMICNG_02272 1.3e-28 yfkK S Belongs to the UPF0435 family
NFMMICNG_02273 6.8e-207 ydiM EGP Major facilitator Superfamily
NFMMICNG_02274 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
NFMMICNG_02275 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NFMMICNG_02276 1.8e-124 yfkO C nitroreductase
NFMMICNG_02277 5.1e-133 treR K transcriptional
NFMMICNG_02278 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NFMMICNG_02279 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NFMMICNG_02280 1.9e-24 yfkQ EG Spore germination protein
NFMMICNG_02281 3.1e-251 agcS_1 E Sodium alanine symporter
NFMMICNG_02282 6e-67 yhdN S Domain of unknown function (DUF1992)
NFMMICNG_02283 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NFMMICNG_02284 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NFMMICNG_02285 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
NFMMICNG_02286 5.3e-50 yflH S Protein of unknown function (DUF3243)
NFMMICNG_02287 4.1e-19 yflI
NFMMICNG_02288 4e-18 yflJ S Protein of unknown function (DUF2639)
NFMMICNG_02289 6.4e-122 yflK S protein conserved in bacteria
NFMMICNG_02290 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NFMMICNG_02291 2.1e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NFMMICNG_02292 2.3e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NFMMICNG_02293 1.9e-226 citM C Citrate transporter
NFMMICNG_02294 4.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
NFMMICNG_02295 8.9e-119 citT T response regulator
NFMMICNG_02296 1.5e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NFMMICNG_02297 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
NFMMICNG_02298 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NFMMICNG_02299 7.6e-58 yflT S Heat induced stress protein YflT
NFMMICNG_02300 2.9e-24 S Protein of unknown function (DUF3212)
NFMMICNG_02301 2.7e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NFMMICNG_02302 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFMMICNG_02303 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFMMICNG_02304 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NFMMICNG_02305 1.8e-187 yfmJ S N-terminal domain of oxidoreductase
NFMMICNG_02306 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
NFMMICNG_02307 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NFMMICNG_02308 2.1e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NFMMICNG_02309 1.5e-209 yfmO EGP Major facilitator Superfamily
NFMMICNG_02310 4e-69 yfmP K transcriptional
NFMMICNG_02311 3.4e-74 yfmQ S Uncharacterised protein from bacillus cereus group
NFMMICNG_02312 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NFMMICNG_02313 1.1e-113 yfmS NT chemotaxis protein
NFMMICNG_02314 1.1e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NFMMICNG_02315 1.4e-240 yfnA E amino acid
NFMMICNG_02316 3.9e-133 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NFMMICNG_02317 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
NFMMICNG_02318 3.3e-188 yfnD M Nucleotide-diphospho-sugar transferase
NFMMICNG_02319 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NFMMICNG_02320 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
NFMMICNG_02321 1.9e-172 yfnG 4.2.1.45 M dehydratase
NFMMICNG_02322 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
NFMMICNG_02323 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NFMMICNG_02324 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NFMMICNG_02325 3.6e-199 yetN S Protein of unknown function (DUF3900)
NFMMICNG_02326 8.3e-31 yetM CH FAD binding domain
NFMMICNG_02327 2.6e-104 yetJ S Belongs to the BI1 family
NFMMICNG_02328 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
NFMMICNG_02329 5.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NFMMICNG_02330 2.2e-34
NFMMICNG_02331 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFMMICNG_02332 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NFMMICNG_02333 4e-122 yetF S membrane
NFMMICNG_02334 8.9e-256 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NFMMICNG_02335 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
NFMMICNG_02336 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NFMMICNG_02337 1.5e-288 lplA G Bacterial extracellular solute-binding protein
NFMMICNG_02338 0.0 yetA
NFMMICNG_02339 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NFMMICNG_02340 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
NFMMICNG_02341 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NFMMICNG_02342 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NFMMICNG_02343 2.2e-111 yesV S Protein of unknown function, DUF624
NFMMICNG_02344 3e-127 yesU S Domain of unknown function (DUF1961)
NFMMICNG_02345 5.1e-130 E GDSL-like Lipase/Acylhydrolase
NFMMICNG_02346 0.0 yesS K Transcriptional regulator
NFMMICNG_02347 3.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NFMMICNG_02348 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
NFMMICNG_02349 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
NFMMICNG_02350 1.6e-246 yesO G Bacterial extracellular solute-binding protein
NFMMICNG_02351 1.4e-201 yesN K helix_turn_helix, arabinose operon control protein
NFMMICNG_02352 0.0 yesM 2.7.13.3 T Histidine kinase
NFMMICNG_02353 1.2e-101 yesL S Protein of unknown function, DUF624
NFMMICNG_02354 1.3e-101 yesJ K Acetyltransferase (GNAT) family
NFMMICNG_02355 5.2e-104 cotJC P Spore Coat
NFMMICNG_02356 1.5e-45 cotJB S CotJB protein
NFMMICNG_02357 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NFMMICNG_02358 5.5e-142 yesF GM NAD(P)H-binding
NFMMICNG_02359 2.5e-77 yesE S SnoaL-like domain
NFMMICNG_02360 8.5e-102 dhaR3 K Transcriptional regulator
NFMMICNG_02362 2.7e-126 yeeN K transcriptional regulatory protein
NFMMICNG_02364 1.6e-213 S Tetratricopeptide repeat
NFMMICNG_02365 1e-39
NFMMICNG_02366 4.1e-26 3.4.24.40 CO amine dehydrogenase activity
NFMMICNG_02367 2e-125 3.4.24.40 CO amine dehydrogenase activity
NFMMICNG_02368 8.7e-101 L endonuclease activity
NFMMICNG_02370 0.0 L nucleic acid phosphodiester bond hydrolysis
NFMMICNG_02371 4.2e-75 S Protein of unknown function, DUF600
NFMMICNG_02372 2.7e-27
NFMMICNG_02374 1.4e-100 S response regulator aspartate phosphatase
NFMMICNG_02376 5.8e-43
NFMMICNG_02378 0.0 L Type III restriction enzyme res subunit
NFMMICNG_02379 1.6e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NFMMICNG_02380 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NFMMICNG_02381 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NFMMICNG_02382 1.3e-148 yerO K Transcriptional regulator
NFMMICNG_02383 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NFMMICNG_02384 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NFMMICNG_02385 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NFMMICNG_02386 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NFMMICNG_02387 6.1e-123 sapB S MgtC SapB transporter
NFMMICNG_02388 2.7e-196 yerI S homoserine kinase type II (protein kinase fold)
NFMMICNG_02389 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
NFMMICNG_02390 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NFMMICNG_02391 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NFMMICNG_02392 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NFMMICNG_02393 8.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NFMMICNG_02394 4.8e-51 yerC S protein conserved in bacteria
NFMMICNG_02395 8.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
NFMMICNG_02396 0.0 yerA 3.5.4.2 F adenine deaminase
NFMMICNG_02397 2.7e-27 S Protein of unknown function (DUF2892)
NFMMICNG_02398 6.4e-227 yjeH E Amino acid permease
NFMMICNG_02399 3.5e-73 K helix_turn_helix ASNC type
NFMMICNG_02400 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
NFMMICNG_02401 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NFMMICNG_02402 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NFMMICNG_02403 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NFMMICNG_02404 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NFMMICNG_02405 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NFMMICNG_02406 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NFMMICNG_02407 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NFMMICNG_02408 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NFMMICNG_02409 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NFMMICNG_02410 4.5e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NFMMICNG_02411 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NFMMICNG_02412 8e-28 yebG S NETI protein
NFMMICNG_02413 8.9e-93 yebE S UPF0316 protein
NFMMICNG_02415 8.3e-116 yebC M Membrane
NFMMICNG_02416 7.8e-212 pbuG S permease
NFMMICNG_02417 9.8e-256 S Domain of unknown function (DUF4179)
NFMMICNG_02418 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
NFMMICNG_02419 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NFMMICNG_02420 0.0 yebA E COG1305 Transglutaminase-like enzymes
NFMMICNG_02421 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NFMMICNG_02422 1.5e-175 yeaC S COG0714 MoxR-like ATPases
NFMMICNG_02423 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NFMMICNG_02424 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NFMMICNG_02425 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NFMMICNG_02426 3.3e-175 yeaA S Protein of unknown function (DUF4003)
NFMMICNG_02427 8.4e-156 ydjP I Alpha/beta hydrolase family
NFMMICNG_02428 1.4e-34 ydjO S Cold-inducible protein YdjO
NFMMICNG_02430 2.3e-150 ydjN U Involved in the tonB-independent uptake of proteins
NFMMICNG_02431 4.5e-64 ydjM M Lytic transglycolase
NFMMICNG_02432 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NFMMICNG_02433 2.7e-258 iolT EGP Major facilitator Superfamily
NFMMICNG_02434 4.7e-196 S Ion transport 2 domain protein
NFMMICNG_02435 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
NFMMICNG_02436 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NFMMICNG_02437 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NFMMICNG_02438 5.1e-114 pspA KT Phage shock protein A
NFMMICNG_02439 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NFMMICNG_02440 7.1e-256 gutA G MFS/sugar transport protein
NFMMICNG_02441 9.4e-200 gutB 1.1.1.14 E Dehydrogenase
NFMMICNG_02442 0.0 K NB-ARC domain
NFMMICNG_02443 1.1e-08 ydjC S Abhydrolase domain containing 18
NFMMICNG_02444 4.9e-257 J LlaJI restriction endonuclease
NFMMICNG_02445 1.2e-199 V AAA domain (dynein-related subfamily)
NFMMICNG_02447 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NFMMICNG_02448 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
NFMMICNG_02449 6.4e-66 KL Phage plasmid primase P4 family
NFMMICNG_02451 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NFMMICNG_02452 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NFMMICNG_02453 7.9e-129 ydiL S CAAX protease self-immunity
NFMMICNG_02454 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NFMMICNG_02455 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NFMMICNG_02456 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NFMMICNG_02457 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NFMMICNG_02458 2.1e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NFMMICNG_02459 0.0 ydiF S ABC transporter
NFMMICNG_02460 2e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NFMMICNG_02461 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NFMMICNG_02462 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NFMMICNG_02463 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NFMMICNG_02464 1.3e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NFMMICNG_02466 7.8e-08
NFMMICNG_02471 7.8e-08
NFMMICNG_02479 2e-08
NFMMICNG_02483 2.7e-143 spo0M S COG4326 Sporulation control protein
NFMMICNG_02484 1.2e-26
NFMMICNG_02485 1.6e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NFMMICNG_02486 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NFMMICNG_02487 1.9e-266 ygaK C Berberine and berberine like
NFMMICNG_02489 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NFMMICNG_02490 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NFMMICNG_02491 1.7e-171 ssuA M Sulfonate ABC transporter
NFMMICNG_02492 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NFMMICNG_02493 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NFMMICNG_02495 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NFMMICNG_02496 4.1e-78 ygaO
NFMMICNG_02497 4.8e-29 K Transcriptional regulator
NFMMICNG_02499 7.9e-114 yhzB S B3/4 domain
NFMMICNG_02500 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NFMMICNG_02501 4.4e-177 yhbB S Putative amidase domain
NFMMICNG_02502 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NFMMICNG_02503 1.2e-109 yhbD K Protein of unknown function (DUF4004)
NFMMICNG_02504 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NFMMICNG_02505 8.5e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NFMMICNG_02506 0.0 prkA T Ser protein kinase
NFMMICNG_02507 2.5e-225 yhbH S Belongs to the UPF0229 family
NFMMICNG_02508 2.2e-76 yhbI K DNA-binding transcription factor activity
NFMMICNG_02509 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NFMMICNG_02510 3.1e-271 yhcA EGP Major facilitator Superfamily
NFMMICNG_02511 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NFMMICNG_02512 2.8e-37 yhcC
NFMMICNG_02513 3.5e-55
NFMMICNG_02514 1.5e-59 yhcF K Transcriptional regulator
NFMMICNG_02515 4.4e-121 yhcG V ABC transporter, ATP-binding protein
NFMMICNG_02516 6.5e-165 yhcH V ABC transporter, ATP-binding protein
NFMMICNG_02517 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NFMMICNG_02518 1e-30 cspB K Cold-shock protein
NFMMICNG_02519 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
NFMMICNG_02520 1.9e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NFMMICNG_02521 4.1e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NFMMICNG_02522 1.1e-77 S Protein of unknown function (DUF2812)
NFMMICNG_02523 1.2e-49 K Transcriptional regulator PadR-like family
NFMMICNG_02524 2e-41 yhcM
NFMMICNG_02525 1.3e-67 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NFMMICNG_02526 2.5e-167 yhcP
NFMMICNG_02527 5.2e-100 yhcQ M Spore coat protein
NFMMICNG_02528 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NFMMICNG_02529 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NFMMICNG_02530 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NFMMICNG_02531 9.3e-68 yhcU S Family of unknown function (DUF5365)
NFMMICNG_02532 9.9e-68 yhcV S COG0517 FOG CBS domain
NFMMICNG_02533 4.6e-120 yhcW 5.4.2.6 S hydrolase
NFMMICNG_02534 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NFMMICNG_02535 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NFMMICNG_02536 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NFMMICNG_02537 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NFMMICNG_02538 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NFMMICNG_02539 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NFMMICNG_02540 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NFMMICNG_02541 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
NFMMICNG_02542 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NFMMICNG_02543 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
NFMMICNG_02544 1.2e-38 yhdB S YhdB-like protein
NFMMICNG_02545 4.8e-54 yhdC S Protein of unknown function (DUF3889)
NFMMICNG_02546 1.5e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NFMMICNG_02547 1e-75 nsrR K Transcriptional regulator
NFMMICNG_02548 3.6e-237 ygxB M Conserved TM helix
NFMMICNG_02549 6.3e-276 ycgB S Stage V sporulation protein R
NFMMICNG_02550 5e-254 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NFMMICNG_02551 1e-139 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NFMMICNG_02552 3.8e-162 citR K Transcriptional regulator
NFMMICNG_02553 1.3e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
NFMMICNG_02554 2.7e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFMMICNG_02555 3.4e-250 yhdG E amino acid
NFMMICNG_02556 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NFMMICNG_02557 7.2e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NFMMICNG_02558 2e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NFMMICNG_02559 8.1e-45 yhdK S Sigma-M inhibitor protein
NFMMICNG_02560 1.5e-200 yhdL S Sigma factor regulator N-terminal
NFMMICNG_02561 1e-84 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NFMMICNG_02562 1.7e-190 yhdN C Aldo keto reductase
NFMMICNG_02563 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NFMMICNG_02564 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NFMMICNG_02565 4.1e-74 cueR K transcriptional
NFMMICNG_02566 4.4e-222 yhdR 2.6.1.1 E Aminotransferase
NFMMICNG_02567 2.1e-239 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NFMMICNG_02568 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NFMMICNG_02569 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NFMMICNG_02570 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NFMMICNG_02572 1.6e-202 yhdY M Mechanosensitive ion channel
NFMMICNG_02573 4.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NFMMICNG_02574 5.3e-137 yheN G deacetylase
NFMMICNG_02575 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NFMMICNG_02576 3.7e-225 nhaC C Na H antiporter
NFMMICNG_02577 5.4e-82 nhaX T Belongs to the universal stress protein A family
NFMMICNG_02578 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NFMMICNG_02579 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NFMMICNG_02580 7.6e-109 yheG GM NAD(P)H-binding
NFMMICNG_02581 6.3e-28 sspB S spore protein
NFMMICNG_02582 1.3e-36 yheE S Family of unknown function (DUF5342)
NFMMICNG_02583 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NFMMICNG_02584 4.3e-216 yheC HJ YheC/D like ATP-grasp
NFMMICNG_02585 1.8e-201 yheB S Belongs to the UPF0754 family
NFMMICNG_02586 9.5e-48 yheA S Belongs to the UPF0342 family
NFMMICNG_02587 2e-205 yhaZ L DNA alkylation repair enzyme
NFMMICNG_02588 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NFMMICNG_02589 3.9e-292 hemZ H coproporphyrinogen III oxidase
NFMMICNG_02590 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NFMMICNG_02591 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NFMMICNG_02593 2.3e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
NFMMICNG_02594 1.1e-26 S YhzD-like protein
NFMMICNG_02595 1.2e-166 yhaQ S ABC transporter, ATP-binding protein
NFMMICNG_02596 1.6e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NFMMICNG_02597 2.2e-224 yhaO L DNA repair exonuclease
NFMMICNG_02598 0.0 yhaN L AAA domain
NFMMICNG_02599 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NFMMICNG_02600 1.6e-21 yhaL S Sporulation protein YhaL
NFMMICNG_02601 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NFMMICNG_02602 8.7e-90 yhaK S Putative zincin peptidase
NFMMICNG_02603 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NFMMICNG_02604 1e-113 hpr K Negative regulator of protease production and sporulation
NFMMICNG_02605 7e-39 yhaH S YtxH-like protein
NFMMICNG_02606 3.6e-80 trpP S Tryptophan transporter TrpP
NFMMICNG_02607 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NFMMICNG_02608 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NFMMICNG_02609 4.6e-137 ecsA V transporter (ATP-binding protein)
NFMMICNG_02610 1.8e-215 ecsB U ABC transporter
NFMMICNG_02611 1.4e-114 ecsC S EcsC protein family
NFMMICNG_02612 5.7e-230 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NFMMICNG_02613 2.7e-231 yhfA C membrane
NFMMICNG_02614 7.9e-27 1.15.1.2 C Rubrerythrin
NFMMICNG_02615 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NFMMICNG_02616 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NFMMICNG_02617 1.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NFMMICNG_02618 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NFMMICNG_02619 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NFMMICNG_02620 5.4e-101 yhgD K Transcriptional regulator
NFMMICNG_02621 2.5e-237 yhgE S YhgE Pip N-terminal domain protein
NFMMICNG_02622 4.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NFMMICNG_02623 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
NFMMICNG_02624 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NFMMICNG_02625 1.7e-72 3.4.13.21 S ASCH
NFMMICNG_02626 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NFMMICNG_02627 2e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NFMMICNG_02628 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
NFMMICNG_02629 1.9e-110 yhfK GM NmrA-like family
NFMMICNG_02630 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NFMMICNG_02631 1.9e-65 yhfM
NFMMICNG_02632 3.5e-241 yhfN 3.4.24.84 O Peptidase M48
NFMMICNG_02633 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NFMMICNG_02634 3.1e-75 VY92_01935 K acetyltransferase
NFMMICNG_02635 5.4e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
NFMMICNG_02636 4.3e-159 yfmC M Periplasmic binding protein
NFMMICNG_02637 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NFMMICNG_02638 5.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
NFMMICNG_02639 6.4e-268 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NFMMICNG_02640 6.5e-91 bioY S BioY family
NFMMICNG_02641 1.7e-182 hemAT NT chemotaxis protein
NFMMICNG_02642 4.7e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NFMMICNG_02643 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFMMICNG_02644 1.3e-32 yhzC S IDEAL
NFMMICNG_02645 4.2e-109 comK K Competence transcription factor
NFMMICNG_02646 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
NFMMICNG_02647 7.8e-42 yhjA S Excalibur calcium-binding domain
NFMMICNG_02648 1.3e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NFMMICNG_02649 6.9e-27 yhjC S Protein of unknown function (DUF3311)
NFMMICNG_02650 6.7e-60 yhjD
NFMMICNG_02651 3.4e-109 yhjE S SNARE associated Golgi protein
NFMMICNG_02652 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NFMMICNG_02653 2.4e-278 yhjG CH FAD binding domain
NFMMICNG_02654 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
NFMMICNG_02655 4.5e-214 glcP G Major Facilitator Superfamily
NFMMICNG_02656 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NFMMICNG_02657 4.5e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NFMMICNG_02658 7.7e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NFMMICNG_02659 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
NFMMICNG_02660 5.1e-199 abrB S membrane
NFMMICNG_02661 7.9e-211 EGP Transmembrane secretion effector
NFMMICNG_02662 0.0 S Sugar transport-related sRNA regulator N-term
NFMMICNG_02663 2.7e-33 yhjQ C COG1145 Ferredoxin
NFMMICNG_02664 1.1e-77 yhjR S Rubrerythrin
NFMMICNG_02665 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NFMMICNG_02666 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NFMMICNG_02667 6.9e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NFMMICNG_02668 0.0 sbcC L COG0419 ATPase involved in DNA repair
NFMMICNG_02669 1.1e-49 yisB V COG1403 Restriction endonuclease
NFMMICNG_02670 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NFMMICNG_02671 3e-66 gerPE S Spore germination protein GerPE
NFMMICNG_02672 6.3e-24 gerPD S Spore germination protein
NFMMICNG_02673 1.8e-54 gerPC S Spore germination protein
NFMMICNG_02674 4e-34 gerPB S cell differentiation
NFMMICNG_02675 1.9e-33 gerPA S Spore germination protein
NFMMICNG_02676 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NFMMICNG_02677 1.1e-172 cotH M Spore Coat
NFMMICNG_02678 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NFMMICNG_02679 3.9e-57 yisL S UPF0344 protein
NFMMICNG_02680 0.0 wprA O Belongs to the peptidase S8 family
NFMMICNG_02681 2.1e-102 yisN S Protein of unknown function (DUF2777)
NFMMICNG_02682 0.0 asnO 6.3.5.4 E Asparagine synthase
NFMMICNG_02683 3.9e-87 yizA S Damage-inducible protein DinB
NFMMICNG_02684 2.8e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NFMMICNG_02685 1.5e-242 yisQ V Mate efflux family protein
NFMMICNG_02686 1.2e-160 yisR K Transcriptional regulator
NFMMICNG_02687 1.5e-183 purR K helix_turn _helix lactose operon repressor
NFMMICNG_02688 1.5e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NFMMICNG_02689 7e-92 yisT S DinB family
NFMMICNG_02690 1.9e-107 argO S Lysine exporter protein LysE YggA
NFMMICNG_02691 1.8e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NFMMICNG_02692 4e-36 mcbG S Pentapeptide repeats (9 copies)
NFMMICNG_02693 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NFMMICNG_02694 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NFMMICNG_02695 2.5e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NFMMICNG_02696 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NFMMICNG_02697 5.3e-119 comB 3.1.3.71 H Belongs to the ComB family
NFMMICNG_02698 5.4e-141 yitD 4.4.1.19 S synthase
NFMMICNG_02699 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NFMMICNG_02700 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NFMMICNG_02701 1.5e-228 yitG EGP Major facilitator Superfamily
NFMMICNG_02702 2e-160 yitH K Acetyltransferase (GNAT) domain
NFMMICNG_02703 7.8e-79 yjcF S Acetyltransferase (GNAT) domain
NFMMICNG_02704 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NFMMICNG_02705 5.6e-54 yajQ S Belongs to the UPF0234 family
NFMMICNG_02706 6.9e-161 cvfB S protein conserved in bacteria
NFMMICNG_02707 8.5e-94
NFMMICNG_02708 1.4e-170
NFMMICNG_02709 1.5e-97 S Sporulation delaying protein SdpA
NFMMICNG_02710 1.5e-58 K Transcriptional regulator PadR-like family
NFMMICNG_02711 2e-95
NFMMICNG_02712 1.4e-44 yitR S Domain of unknown function (DUF3784)
NFMMICNG_02713 1.6e-307 nprB 3.4.24.28 E Peptidase M4
NFMMICNG_02714 8.4e-159 yitS S protein conserved in bacteria
NFMMICNG_02715 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NFMMICNG_02716 5e-73 ipi S Intracellular proteinase inhibitor
NFMMICNG_02717 1.2e-17 S Protein of unknown function (DUF3813)
NFMMICNG_02718 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NFMMICNG_02719 1e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NFMMICNG_02720 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NFMMICNG_02721 1.5e-22 pilT S Proteolipid membrane potential modulator
NFMMICNG_02722 6e-266 yitY C D-arabinono-1,4-lactone oxidase
NFMMICNG_02723 1.7e-88 norB G Major Facilitator Superfamily
NFMMICNG_02724 1.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NFMMICNG_02725 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NFMMICNG_02726 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NFMMICNG_02727 6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NFMMICNG_02728 9.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NFMMICNG_02729 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NFMMICNG_02730 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NFMMICNG_02731 9.5e-28 yjzC S YjzC-like protein
NFMMICNG_02732 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NFMMICNG_02733 6.8e-141 yjaU I carboxylic ester hydrolase activity
NFMMICNG_02734 1.8e-101 yjaV
NFMMICNG_02735 1.1e-183 med S Transcriptional activator protein med
NFMMICNG_02736 4.7e-25 comZ S ComZ
NFMMICNG_02737 2.7e-22 yjzB
NFMMICNG_02738 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NFMMICNG_02739 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NFMMICNG_02740 7.8e-151 yjaZ O Zn-dependent protease
NFMMICNG_02741 1.8e-184 appD P Belongs to the ABC transporter superfamily
NFMMICNG_02742 6.5e-187 appF E Belongs to the ABC transporter superfamily
NFMMICNG_02743 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NFMMICNG_02744 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NFMMICNG_02745 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NFMMICNG_02746 6.5e-147 yjbA S Belongs to the UPF0736 family
NFMMICNG_02747 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NFMMICNG_02748 0.0 oppA E ABC transporter substrate-binding protein
NFMMICNG_02749 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NFMMICNG_02750 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NFMMICNG_02751 1.5e-197 oppD P Belongs to the ABC transporter superfamily
NFMMICNG_02752 5.5e-172 oppF E Belongs to the ABC transporter superfamily
NFMMICNG_02753 1.2e-203 yjbB EGP Major Facilitator Superfamily
NFMMICNG_02754 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NFMMICNG_02755 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NFMMICNG_02756 6e-112 yjbE P Integral membrane protein TerC family
NFMMICNG_02757 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NFMMICNG_02758 2.1e-221 yjbF S Competence protein
NFMMICNG_02759 0.0 pepF E oligoendopeptidase F
NFMMICNG_02760 1.8e-20
NFMMICNG_02762 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NFMMICNG_02763 1.1e-71 yjbI S Bacterial-like globin
NFMMICNG_02764 3.8e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NFMMICNG_02765 1e-99 yjbK S protein conserved in bacteria
NFMMICNG_02766 1.6e-61 yjbL S Belongs to the UPF0738 family
NFMMICNG_02767 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NFMMICNG_02768 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NFMMICNG_02769 2.3e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NFMMICNG_02770 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NFMMICNG_02771 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NFMMICNG_02772 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NFMMICNG_02773 9.3e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NFMMICNG_02774 1.2e-213 thiO 1.4.3.19 E Glycine oxidase
NFMMICNG_02775 2.6e-29 thiS H thiamine diphosphate biosynthetic process
NFMMICNG_02776 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NFMMICNG_02777 5.1e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NFMMICNG_02778 2.2e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NFMMICNG_02779 9.5e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NFMMICNG_02780 5.9e-54 yjbX S Spore coat protein
NFMMICNG_02781 4.4e-82 cotZ S Spore coat protein
NFMMICNG_02782 7.6e-96 cotY S Spore coat protein Z
NFMMICNG_02783 1.6e-72 cotX S Spore Coat Protein X and V domain
NFMMICNG_02784 8.8e-24 cotW
NFMMICNG_02785 1.1e-54 cotV S Spore Coat Protein X and V domain
NFMMICNG_02786 4.3e-56 yjcA S Protein of unknown function (DUF1360)
NFMMICNG_02789 2.9e-38 spoVIF S Stage VI sporulation protein F
NFMMICNG_02790 0.0 yjcD 3.6.4.12 L DNA helicase
NFMMICNG_02791 1.7e-38
NFMMICNG_02792 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NFMMICNG_02793 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NFMMICNG_02794 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
NFMMICNG_02795 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NFMMICNG_02796 4.2e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NFMMICNG_02797 7.7e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
NFMMICNG_02798 5.4e-212 yjcL S Protein of unknown function (DUF819)
NFMMICNG_02801 7.8e-190 S Putative amidase domain
NFMMICNG_02802 2.6e-44 yjcN
NFMMICNG_02805 8.5e-81 L Transposase
NFMMICNG_02806 5.3e-71 yjcP
NFMMICNG_02807 4.1e-49 S YjcQ protein
NFMMICNG_02808 1.1e-92 yqaS L DNA packaging
NFMMICNG_02809 2.4e-33 yjcS S Antibiotic biosynthesis monooxygenase
NFMMICNG_02810 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
NFMMICNG_02812 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NFMMICNG_02813 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NFMMICNG_02814 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NFMMICNG_02815 4.5e-49 yjdF S Protein of unknown function (DUF2992)
NFMMICNG_02816 4.5e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NFMMICNG_02818 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NFMMICNG_02819 4.2e-29 S Domain of unknown function (DUF4177)
NFMMICNG_02820 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
NFMMICNG_02821 1.4e-173 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NFMMICNG_02823 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
NFMMICNG_02824 1.4e-81 S Protein of unknown function (DUF2690)
NFMMICNG_02825 8.9e-20 yjfB S Putative motility protein
NFMMICNG_02826 5.6e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
NFMMICNG_02827 1.2e-45 T PhoQ Sensor
NFMMICNG_02828 8.9e-104 yjgB S Domain of unknown function (DUF4309)
NFMMICNG_02829 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NFMMICNG_02830 4.3e-95 yjgD S Protein of unknown function (DUF1641)
NFMMICNG_02831 8.7e-07 S Domain of unknown function (DUF4352)
NFMMICNG_02832 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NFMMICNG_02834 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NFMMICNG_02835 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NFMMICNG_02836 8.2e-30
NFMMICNG_02837 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NFMMICNG_02838 1.9e-122 ybbM S transport system, permease component
NFMMICNG_02839 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NFMMICNG_02840 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
NFMMICNG_02841 2.8e-93 yjlB S Cupin domain
NFMMICNG_02842 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NFMMICNG_02843 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
NFMMICNG_02844 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
NFMMICNG_02845 5.8e-250 yjmB G symporter YjmB
NFMMICNG_02846 4.3e-194 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NFMMICNG_02847 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NFMMICNG_02848 2.3e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NFMMICNG_02849 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NFMMICNG_02850 3.7e-227 exuT G Sugar (and other) transporter
NFMMICNG_02851 2.3e-184 exuR K transcriptional
NFMMICNG_02852 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NFMMICNG_02853 4.6e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NFMMICNG_02854 7.4e-130 MA20_18170 S membrane transporter protein
NFMMICNG_02855 2.3e-78 yjoA S DinB family
NFMMICNG_02856 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NFMMICNG_02857 1e-212 S response regulator aspartate phosphatase
NFMMICNG_02859 5.2e-37 S YCII-related domain
NFMMICNG_02860 6.8e-165 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NFMMICNG_02861 1.8e-60 yjqA S Bacterial PH domain
NFMMICNG_02862 2.1e-111 yjqB S Pfam:DUF867
NFMMICNG_02863 9.8e-160 ydbD P Catalase
NFMMICNG_02864 4.3e-109 xkdA E IrrE N-terminal-like domain
NFMMICNG_02865 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
NFMMICNG_02867 5e-156 xkdB K sequence-specific DNA binding
NFMMICNG_02868 9.2e-118 xkdC L Bacterial dnaA protein
NFMMICNG_02871 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
NFMMICNG_02872 2.2e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NFMMICNG_02873 5.3e-139 xtmA L phage terminase small subunit
NFMMICNG_02874 1.4e-253 xtmB S phage terminase, large subunit
NFMMICNG_02875 6e-285 yqbA S portal protein
NFMMICNG_02876 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NFMMICNG_02877 1.3e-168 xkdG S Phage capsid family
NFMMICNG_02878 5.5e-65 yqbG S Protein of unknown function (DUF3199)
NFMMICNG_02879 8.7e-65 yqbH S Domain of unknown function (DUF3599)
NFMMICNG_02880 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
NFMMICNG_02881 1.9e-77 xkdJ
NFMMICNG_02882 2.5e-256 xkdK S Phage tail sheath C-terminal domain
NFMMICNG_02883 6.1e-76 xkdM S Phage tail tube protein
NFMMICNG_02884 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
NFMMICNG_02885 0.0 xkdO L Transglycosylase SLT domain
NFMMICNG_02886 4.1e-121 xkdP S Lysin motif
NFMMICNG_02887 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
NFMMICNG_02888 2.1e-39 xkdR S Protein of unknown function (DUF2577)
NFMMICNG_02889 3.1e-69 xkdS S Protein of unknown function (DUF2634)
NFMMICNG_02890 6.7e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NFMMICNG_02891 1.2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NFMMICNG_02892 1.5e-40
NFMMICNG_02893 1e-261
NFMMICNG_02894 5.4e-53 xkdW S XkdW protein
NFMMICNG_02895 5.5e-22 xkdX
NFMMICNG_02896 1.7e-151 xepA
NFMMICNG_02897 6.2e-39 xhlA S Haemolysin XhlA
NFMMICNG_02898 9.3e-40 xhlB S SPP1 phage holin
NFMMICNG_02899 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NFMMICNG_02900 6.7e-23 spoIISB S Stage II sporulation protein SB
NFMMICNG_02901 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NFMMICNG_02902 5.8e-175 pit P phosphate transporter
NFMMICNG_02903 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NFMMICNG_02904 4e-240 steT E amino acid
NFMMICNG_02905 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NFMMICNG_02906 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NFMMICNG_02907 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NFMMICNG_02909 7.5e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NFMMICNG_02910 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NFMMICNG_02911 2.5e-152 dppA E D-aminopeptidase
NFMMICNG_02912 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NFMMICNG_02913 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NFMMICNG_02914 1.3e-187 dppD P Belongs to the ABC transporter superfamily
NFMMICNG_02915 0.0 dppE E ABC transporter substrate-binding protein
NFMMICNG_02917 1.3e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NFMMICNG_02918 2.3e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NFMMICNG_02919 2.7e-163 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NFMMICNG_02920 9.4e-186 ykfD E Belongs to the ABC transporter superfamily
NFMMICNG_02921 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
NFMMICNG_02922 2e-160 ykgA E Amidinotransferase
NFMMICNG_02923 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NFMMICNG_02924 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NFMMICNG_02925 5.5e-09
NFMMICNG_02926 7.8e-129 ykjA S Protein of unknown function (DUF421)
NFMMICNG_02927 4.8e-96 ykkA S Protein of unknown function (DUF664)
NFMMICNG_02928 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NFMMICNG_02929 3.5e-55 ykkC P Multidrug resistance protein
NFMMICNG_02930 7e-50 ykkD P Multidrug resistance protein
NFMMICNG_02931 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NFMMICNG_02932 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NFMMICNG_02933 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NFMMICNG_02934 1.3e-70 ohrA O Organic hydroperoxide resistance protein
NFMMICNG_02935 4.8e-73 ohrR K COG1846 Transcriptional regulators
NFMMICNG_02936 2.4e-71 ohrB O Organic hydroperoxide resistance protein
NFMMICNG_02938 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NFMMICNG_02939 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NFMMICNG_02940 1.6e-174 isp O Belongs to the peptidase S8 family
NFMMICNG_02941 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NFMMICNG_02942 5.3e-136 ykoC P Cobalt transport protein
NFMMICNG_02943 2.2e-304 P ABC transporter, ATP-binding protein
NFMMICNG_02944 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
NFMMICNG_02945 1.6e-108 ykoF S YKOF-related Family
NFMMICNG_02946 7.9e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFMMICNG_02947 1.4e-240 ykoH 2.7.13.3 T Histidine kinase
NFMMICNG_02948 9.9e-110 ykoI S Peptidase propeptide and YPEB domain
NFMMICNG_02949 8.3e-85 ykoJ S Peptidase propeptide and YPEB domain
NFMMICNG_02952 2.2e-222 mgtE P Acts as a magnesium transporter
NFMMICNG_02953 1.4e-53 tnrA K transcriptional
NFMMICNG_02954 5.9e-18
NFMMICNG_02955 6.9e-26 ykoL
NFMMICNG_02956 1.3e-81 mhqR K transcriptional
NFMMICNG_02957 3.1e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NFMMICNG_02958 1.4e-98 ykoP G polysaccharide deacetylase
NFMMICNG_02959 3.5e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NFMMICNG_02960 0.0 ykoS
NFMMICNG_02961 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NFMMICNG_02962 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NFMMICNG_02963 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NFMMICNG_02964 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
NFMMICNG_02965 3.5e-109 ykoX S membrane-associated protein
NFMMICNG_02966 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NFMMICNG_02967 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFMMICNG_02968 9.1e-116 rsgI S Anti-sigma factor N-terminus
NFMMICNG_02969 1.9e-26 sspD S small acid-soluble spore protein
NFMMICNG_02970 1.5e-124 ykrK S Domain of unknown function (DUF1836)
NFMMICNG_02971 3.5e-155 htpX O Belongs to the peptidase M48B family
NFMMICNG_02972 1.1e-232 ktrB P COG0168 Trk-type K transport systems, membrane components
NFMMICNG_02973 1.2e-10 ydfR S Protein of unknown function (DUF421)
NFMMICNG_02974 4.1e-18 ykzE
NFMMICNG_02975 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NFMMICNG_02976 0.0 kinE 2.7.13.3 T Histidine kinase
NFMMICNG_02977 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NFMMICNG_02979 1.4e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NFMMICNG_02980 2.4e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NFMMICNG_02981 1e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NFMMICNG_02982 1.5e-230 mtnE 2.6.1.83 E Aminotransferase
NFMMICNG_02983 1.4e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NFMMICNG_02984 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NFMMICNG_02985 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NFMMICNG_02986 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NFMMICNG_02987 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
NFMMICNG_02988 6.4e-09 S Spo0E like sporulation regulatory protein
NFMMICNG_02989 1.8e-64 eag
NFMMICNG_02990 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NFMMICNG_02991 1.3e-75 ykvE K transcriptional
NFMMICNG_02992 2.5e-125 motB N Flagellar motor protein
NFMMICNG_02993 1e-137 motA N flagellar motor
NFMMICNG_02994 0.0 clpE O Belongs to the ClpA ClpB family
NFMMICNG_02995 2.6e-178 ykvI S membrane
NFMMICNG_02996 9.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NFMMICNG_02997 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NFMMICNG_02998 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NFMMICNG_02999 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NFMMICNG_03000 2e-61 ykvN K Transcriptional regulator
NFMMICNG_03001 2.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
NFMMICNG_03002 9.9e-216 ykvP 3.5.1.28 M Glycosyl transferases group 1
NFMMICNG_03003 3.5e-35 3.5.1.104 M LysM domain
NFMMICNG_03004 1.4e-162 G Glycosyl hydrolases family 18
NFMMICNG_03005 5.6e-46 ykvR S Protein of unknown function (DUF3219)
NFMMICNG_03006 6e-25 ykvS S protein conserved in bacteria
NFMMICNG_03007 2.8e-28
NFMMICNG_03008 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
NFMMICNG_03009 3.8e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NFMMICNG_03010 1.6e-88 stoA CO thiol-disulfide
NFMMICNG_03011 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NFMMICNG_03012 2.3e-09
NFMMICNG_03013 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NFMMICNG_03014 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
NFMMICNG_03016 2.2e-127 glcT K antiterminator
NFMMICNG_03017 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NFMMICNG_03018 2.1e-39 ptsH G phosphocarrier protein HPr
NFMMICNG_03019 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NFMMICNG_03020 7.2e-39 splA S Transcriptional regulator
NFMMICNG_03021 7.5e-202 splB 4.1.99.14 L Spore photoproduct lyase
NFMMICNG_03022 4.9e-128 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NFMMICNG_03023 1.6e-261 mcpC NT chemotaxis protein
NFMMICNG_03024 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NFMMICNG_03025 8e-124 ykwD J protein with SCP PR1 domains
NFMMICNG_03026 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NFMMICNG_03027 0.0 pilS 2.7.13.3 T Histidine kinase
NFMMICNG_03028 8e-224 patA 2.6.1.1 E Aminotransferase
NFMMICNG_03029 2.2e-15
NFMMICNG_03030 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NFMMICNG_03031 1.7e-84 ykyB S YkyB-like protein
NFMMICNG_03032 1.7e-235 ykuC EGP Major facilitator Superfamily
NFMMICNG_03033 1.5e-86 ykuD S protein conserved in bacteria
NFMMICNG_03034 1.6e-165 ykuE S Metallophosphoesterase
NFMMICNG_03035 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFMMICNG_03036 5.2e-234 ykuI T Diguanylate phosphodiesterase
NFMMICNG_03037 3.9e-37 ykuJ S protein conserved in bacteria
NFMMICNG_03038 4.4e-94 ykuK S Ribonuclease H-like
NFMMICNG_03039 3.9e-27 ykzF S Antirepressor AbbA
NFMMICNG_03040 1.6e-76 ykuL S CBS domain
NFMMICNG_03041 3.5e-168 ccpC K Transcriptional regulator
NFMMICNG_03042 8.5e-84 fld C Flavodoxin domain
NFMMICNG_03043 3e-175 ykuO
NFMMICNG_03044 3.9e-78 fld C Flavodoxin
NFMMICNG_03045 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NFMMICNG_03046 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NFMMICNG_03047 9e-37 ykuS S Belongs to the UPF0180 family
NFMMICNG_03048 8.8e-142 ykuT M Mechanosensitive ion channel
NFMMICNG_03049 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NFMMICNG_03050 7e-80 ykuV CO thiol-disulfide
NFMMICNG_03051 5.8e-95 rok K Repressor of ComK
NFMMICNG_03052 4.2e-146 yknT
NFMMICNG_03053 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NFMMICNG_03054 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NFMMICNG_03055 8.1e-246 moeA 2.10.1.1 H molybdopterin
NFMMICNG_03056 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NFMMICNG_03057 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NFMMICNG_03058 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NFMMICNG_03059 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NFMMICNG_03060 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NFMMICNG_03061 1e-117 yknW S Yip1 domain
NFMMICNG_03062 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NFMMICNG_03063 2.5e-124 macB V ABC transporter, ATP-binding protein
NFMMICNG_03064 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NFMMICNG_03065 3.1e-136 fruR K Transcriptional regulator
NFMMICNG_03066 3.1e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NFMMICNG_03067 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NFMMICNG_03068 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NFMMICNG_03069 8.1e-39 ykoA
NFMMICNG_03070 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NFMMICNG_03071 1.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NFMMICNG_03072 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NFMMICNG_03073 1.1e-12 S Uncharacterized protein YkpC
NFMMICNG_03074 7.7e-183 mreB D Rod-share determining protein MreBH
NFMMICNG_03075 1.5e-43 abrB K of stationary sporulation gene expression
NFMMICNG_03076 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NFMMICNG_03077 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NFMMICNG_03078 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NFMMICNG_03079 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NFMMICNG_03080 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NFMMICNG_03081 8.2e-31 ykzG S Belongs to the UPF0356 family
NFMMICNG_03082 1.4e-147 ykrA S hydrolases of the HAD superfamily
NFMMICNG_03083 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NFMMICNG_03085 2e-115 recN L Putative cell-wall binding lipoprotein
NFMMICNG_03086 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NFMMICNG_03087 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NFMMICNG_03088 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NFMMICNG_03089 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NFMMICNG_03090 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NFMMICNG_03091 3.5e-277 speA 4.1.1.19 E Arginine
NFMMICNG_03092 1.6e-42 yktA S Belongs to the UPF0223 family
NFMMICNG_03093 4.6e-117 yktB S Belongs to the UPF0637 family
NFMMICNG_03094 7.1e-26 ykzI
NFMMICNG_03095 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
NFMMICNG_03096 2.2e-76 ykzC S Acetyltransferase (GNAT) family
NFMMICNG_03097 8.7e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NFMMICNG_03098 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NFMMICNG_03099 0.0 ylaA
NFMMICNG_03100 2.7e-42 ylaB
NFMMICNG_03101 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NFMMICNG_03102 7.1e-12 sigC S Putative zinc-finger
NFMMICNG_03103 4.1e-38 ylaE
NFMMICNG_03104 8.2e-22 S Family of unknown function (DUF5325)
NFMMICNG_03105 0.0 typA T GTP-binding protein TypA
NFMMICNG_03106 4.2e-47 ylaH S YlaH-like protein
NFMMICNG_03107 2.5e-32 ylaI S protein conserved in bacteria
NFMMICNG_03108 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NFMMICNG_03109 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NFMMICNG_03110 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NFMMICNG_03111 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NFMMICNG_03112 8.7e-44 ylaN S Belongs to the UPF0358 family
NFMMICNG_03113 4.5e-214 ftsW D Belongs to the SEDS family
NFMMICNG_03114 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NFMMICNG_03115 7.7e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NFMMICNG_03116 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NFMMICNG_03117 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NFMMICNG_03118 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NFMMICNG_03119 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NFMMICNG_03120 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NFMMICNG_03121 3.4e-166 ctaG S cytochrome c oxidase
NFMMICNG_03122 7e-62 ylbA S YugN-like family
NFMMICNG_03123 2.6e-74 ylbB T COG0517 FOG CBS domain
NFMMICNG_03124 9.6e-200 ylbC S protein with SCP PR1 domains
NFMMICNG_03125 4.1e-63 ylbD S Putative coat protein
NFMMICNG_03126 2.5e-36 ylbE S YlbE-like protein
NFMMICNG_03127 1.8e-75 ylbF S Belongs to the UPF0342 family
NFMMICNG_03128 3.7e-38 ylbG S UPF0298 protein
NFMMICNG_03129 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
NFMMICNG_03130 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NFMMICNG_03131 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
NFMMICNG_03132 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
NFMMICNG_03133 6.8e-187 ylbL T Belongs to the peptidase S16 family
NFMMICNG_03134 4e-234 ylbM S Belongs to the UPF0348 family
NFMMICNG_03136 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
NFMMICNG_03137 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NFMMICNG_03138 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NFMMICNG_03139 1.5e-88 ylbP K n-acetyltransferase
NFMMICNG_03140 6.1e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NFMMICNG_03141 3.2e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NFMMICNG_03142 2.9e-78 mraZ K Belongs to the MraZ family
NFMMICNG_03143 4.7e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NFMMICNG_03144 3.7e-44 ftsL D Essential cell division protein
NFMMICNG_03145 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NFMMICNG_03146 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NFMMICNG_03147 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NFMMICNG_03148 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NFMMICNG_03149 1.9e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NFMMICNG_03150 5.7e-186 spoVE D Belongs to the SEDS family
NFMMICNG_03151 6.7e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NFMMICNG_03152 5.3e-167 murB 1.3.1.98 M cell wall formation
NFMMICNG_03153 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NFMMICNG_03154 4.1e-103 ylxW S protein conserved in bacteria
NFMMICNG_03155 2.6e-90 ylxX S protein conserved in bacteria
NFMMICNG_03156 2.8e-55 sbp S small basic protein
NFMMICNG_03157 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NFMMICNG_03158 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NFMMICNG_03159 0.0 bpr O COG1404 Subtilisin-like serine proteases
NFMMICNG_03160 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NFMMICNG_03161 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFMMICNG_03162 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFMMICNG_03163 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NFMMICNG_03164 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
NFMMICNG_03165 2.4e-37 ylmC S sporulation protein
NFMMICNG_03166 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NFMMICNG_03167 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NFMMICNG_03168 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NFMMICNG_03169 1.6e-39 yggT S membrane
NFMMICNG_03170 8.2e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NFMMICNG_03171 2.6e-67 divIVA D Cell division initiation protein
NFMMICNG_03172 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NFMMICNG_03173 1.3e-63 dksA T COG1734 DnaK suppressor protein
NFMMICNG_03174 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NFMMICNG_03175 3.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NFMMICNG_03176 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NFMMICNG_03177 2.6e-231 pyrP F Xanthine uracil
NFMMICNG_03178 8.5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NFMMICNG_03179 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NFMMICNG_03180 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NFMMICNG_03181 0.0 carB 6.3.5.5 F Belongs to the CarB family
NFMMICNG_03182 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NFMMICNG_03183 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NFMMICNG_03184 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NFMMICNG_03185 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NFMMICNG_03187 1.7e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NFMMICNG_03188 1.2e-178 cysP P phosphate transporter
NFMMICNG_03189 1.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NFMMICNG_03190 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NFMMICNG_03191 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NFMMICNG_03192 2.2e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NFMMICNG_03193 6.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NFMMICNG_03194 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NFMMICNG_03195 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NFMMICNG_03196 3.1e-156 yloC S stress-induced protein
NFMMICNG_03197 1.5e-40 ylzA S Belongs to the UPF0296 family
NFMMICNG_03198 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NFMMICNG_03199 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NFMMICNG_03200 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NFMMICNG_03201 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NFMMICNG_03202 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NFMMICNG_03203 5.2e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NFMMICNG_03204 5.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NFMMICNG_03205 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NFMMICNG_03206 1.6e-140 stp 3.1.3.16 T phosphatase
NFMMICNG_03207 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NFMMICNG_03208 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NFMMICNG_03209 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NFMMICNG_03210 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NFMMICNG_03211 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NFMMICNG_03212 5.5e-59 asp S protein conserved in bacteria
NFMMICNG_03213 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
NFMMICNG_03214 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NFMMICNG_03215 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NFMMICNG_03216 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NFMMICNG_03217 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NFMMICNG_03218 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NFMMICNG_03219 2.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NFMMICNG_03220 1.1e-127 IQ reductase
NFMMICNG_03221 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NFMMICNG_03222 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NFMMICNG_03223 0.0 smc D Required for chromosome condensation and partitioning
NFMMICNG_03224 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NFMMICNG_03225 3.5e-85
NFMMICNG_03226 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NFMMICNG_03227 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NFMMICNG_03228 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NFMMICNG_03229 4.5e-36 ylqC S Belongs to the UPF0109 family
NFMMICNG_03230 6.3e-61 ylqD S YlqD protein
NFMMICNG_03231 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NFMMICNG_03232 7.8e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NFMMICNG_03233 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NFMMICNG_03234 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NFMMICNG_03235 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NFMMICNG_03236 4.3e-287 ylqG
NFMMICNG_03237 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NFMMICNG_03238 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NFMMICNG_03239 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NFMMICNG_03240 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NFMMICNG_03241 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NFMMICNG_03242 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NFMMICNG_03243 2.5e-169 xerC L tyrosine recombinase XerC
NFMMICNG_03244 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NFMMICNG_03245 4.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NFMMICNG_03246 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NFMMICNG_03247 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NFMMICNG_03248 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
NFMMICNG_03249 1.9e-31 fliE N Flagellar hook-basal body
NFMMICNG_03250 1.6e-254 fliF N The M ring may be actively involved in energy transduction
NFMMICNG_03251 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NFMMICNG_03252 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NFMMICNG_03253 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NFMMICNG_03254 1.5e-69 fliJ N Flagellar biosynthesis chaperone
NFMMICNG_03255 2.2e-36 ylxF S MgtE intracellular N domain
NFMMICNG_03256 5.1e-220 fliK N Flagellar hook-length control protein
NFMMICNG_03257 2.3e-72 flgD N Flagellar basal body rod modification protein
NFMMICNG_03258 8.2e-140 flgG N Flagellar basal body rod
NFMMICNG_03259 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NFMMICNG_03260 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NFMMICNG_03261 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NFMMICNG_03262 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NFMMICNG_03263 2.7e-96 fliZ N Flagellar biosynthesis protein, FliO
NFMMICNG_03264 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NFMMICNG_03265 3.6e-132 fliR N Flagellar biosynthetic protein FliR
NFMMICNG_03266 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NFMMICNG_03267 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NFMMICNG_03268 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
NFMMICNG_03269 4.1e-156 flhG D Belongs to the ParA family
NFMMICNG_03270 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NFMMICNG_03271 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NFMMICNG_03272 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NFMMICNG_03273 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NFMMICNG_03274 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NFMMICNG_03275 9.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFMMICNG_03276 3.1e-76 ylxL
NFMMICNG_03277 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NFMMICNG_03278 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NFMMICNG_03279 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NFMMICNG_03280 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NFMMICNG_03281 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NFMMICNG_03282 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NFMMICNG_03283 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NFMMICNG_03284 7.7e-233 rasP M zinc metalloprotease
NFMMICNG_03285 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NFMMICNG_03286 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NFMMICNG_03287 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NFMMICNG_03288 1.1e-203 nusA K Participates in both transcription termination and antitermination
NFMMICNG_03289 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NFMMICNG_03290 3.1e-47 ylxQ J ribosomal protein
NFMMICNG_03291 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NFMMICNG_03292 3e-44 ylxP S protein conserved in bacteria
NFMMICNG_03293 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NFMMICNG_03294 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NFMMICNG_03295 1.1e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NFMMICNG_03296 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NFMMICNG_03297 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NFMMICNG_03298 6.1e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NFMMICNG_03299 4.4e-233 pepR S Belongs to the peptidase M16 family
NFMMICNG_03300 2.6e-42 ymxH S YlmC YmxH family
NFMMICNG_03301 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NFMMICNG_03302 6.3e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NFMMICNG_03303 1.2e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NFMMICNG_03304 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NFMMICNG_03305 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NFMMICNG_03306 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NFMMICNG_03307 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NFMMICNG_03308 4.4e-32 S YlzJ-like protein
NFMMICNG_03309 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NFMMICNG_03310 1.4e-133 ymfC K Transcriptional regulator
NFMMICNG_03311 3.8e-205 ymfD EGP Major facilitator Superfamily
NFMMICNG_03312 2e-233 ymfF S Peptidase M16
NFMMICNG_03313 1.4e-242 ymfH S zinc protease
NFMMICNG_03314 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NFMMICNG_03315 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NFMMICNG_03316 2.7e-143 ymfK S Protein of unknown function (DUF3388)
NFMMICNG_03317 7.3e-116 ymfM S protein conserved in bacteria
NFMMICNG_03318 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NFMMICNG_03319 1.3e-235 cinA 3.5.1.42 S Belongs to the CinA family
NFMMICNG_03320 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NFMMICNG_03321 1e-215 pbpX V Beta-lactamase
NFMMICNG_03322 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NFMMICNG_03323 1.9e-152 ymdB S protein conserved in bacteria
NFMMICNG_03324 1.2e-36 spoVS S Stage V sporulation protein S
NFMMICNG_03325 1.9e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NFMMICNG_03326 3e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NFMMICNG_03327 1.9e-294 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NFMMICNG_03328 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NFMMICNG_03329 2.2e-88 cotE S Spore coat protein
NFMMICNG_03330 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NFMMICNG_03331 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NFMMICNG_03332 2.5e-69 S Regulatory protein YrvL
NFMMICNG_03334 1.2e-97 ymcC S Membrane
NFMMICNG_03335 4.4e-109 pksA K Transcriptional regulator
NFMMICNG_03336 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
NFMMICNG_03337 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NFMMICNG_03339 2.4e-186 pksD Q Acyl transferase domain
NFMMICNG_03340 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NFMMICNG_03341 1.4e-37 acpK IQ Phosphopantetheine attachment site
NFMMICNG_03342 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NFMMICNG_03343 1.3e-245 pksG 2.3.3.10 I synthase
NFMMICNG_03344 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
NFMMICNG_03345 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NFMMICNG_03346 0.0 rhiB IQ polyketide synthase
NFMMICNG_03347 0.0 pfaA Q Polyketide synthase of type I
NFMMICNG_03348 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
NFMMICNG_03349 0.0 dhbF IQ polyketide synthase
NFMMICNG_03350 0.0 pks13 HQ Beta-ketoacyl synthase
NFMMICNG_03351 6.3e-232 cypA C Cytochrome P450
NFMMICNG_03352 2e-61 ymzB
NFMMICNG_03353 8.1e-162 ymaE S Metallo-beta-lactamase superfamily
NFMMICNG_03354 8.6e-251 aprX O Belongs to the peptidase S8 family
NFMMICNG_03355 1.9e-07 K Transcriptional regulator
NFMMICNG_03356 2.1e-126 ymaC S Replication protein
NFMMICNG_03357 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
NFMMICNG_03358 8.9e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NFMMICNG_03359 5.4e-50 ebrA P Small Multidrug Resistance protein
NFMMICNG_03361 2.1e-46 ymaF S YmaF family
NFMMICNG_03362 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NFMMICNG_03363 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NFMMICNG_03364 8.2e-23
NFMMICNG_03365 4.5e-22 ymzA
NFMMICNG_03366 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NFMMICNG_03367 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NFMMICNG_03368 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NFMMICNG_03369 2e-109 ymaB
NFMMICNG_03370 2.6e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NFMMICNG_03371 1.7e-176 spoVK O stage V sporulation protein K
NFMMICNG_03372 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NFMMICNG_03373 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NFMMICNG_03374 1.1e-68 glnR K transcriptional
NFMMICNG_03375 7e-261 glnA 6.3.1.2 E glutamine synthetase
NFMMICNG_03376 1.1e-09
NFMMICNG_03377 1.6e-31
NFMMICNG_03378 2.1e-16
NFMMICNG_03379 8.9e-90 G SMI1-KNR4 cell-wall
NFMMICNG_03380 3.1e-113 ynaC
NFMMICNG_03381 4.1e-11 S Protein of unknown function (DUF1433)
NFMMICNG_03382 2e-97 ynaD J Acetyltransferase (GNAT) domain
NFMMICNG_03383 4.1e-73 S CAAX protease self-immunity
NFMMICNG_03384 4.7e-08 S Uncharacterised protein family (UPF0715)
NFMMICNG_03385 5.5e-20 K Cro/C1-type HTH DNA-binding domain
NFMMICNG_03386 2.1e-117 ynaE S Domain of unknown function (DUF3885)
NFMMICNG_03387 8.6e-15 ynaF
NFMMICNG_03389 8.7e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NFMMICNG_03390 7.9e-255 xynT G MFS/sugar transport protein
NFMMICNG_03391 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NFMMICNG_03392 6.8e-212 xylR GK ROK family
NFMMICNG_03393 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NFMMICNG_03394 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NFMMICNG_03395 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
NFMMICNG_03396 1.4e-254 iolT EGP Major facilitator Superfamily
NFMMICNG_03397 4.5e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NFMMICNG_03399 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NFMMICNG_03400 5.2e-15
NFMMICNG_03403 2.1e-162 S Thymidylate synthase
NFMMICNG_03405 1.7e-48 S Domain of unknown function, YrpD
NFMMICNG_03406 1.1e-69 S Domain of unknown function, YrpD
NFMMICNG_03409 7.9e-25 tatA U protein secretion
NFMMICNG_03410 1.8e-71
NFMMICNG_03411 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NFMMICNG_03414 2.8e-52 gerAA EG Spore germination protein
NFMMICNG_03415 1.8e-146 gerAA EG Spore germination protein
NFMMICNG_03416 3.4e-88 gerLC S Spore germination protein
NFMMICNG_03417 7.7e-154 yndG S DoxX-like family
NFMMICNG_03418 2.6e-117 yndH S Domain of unknown function (DUF4166)
NFMMICNG_03419 0.0 yndJ S YndJ-like protein
NFMMICNG_03421 8.6e-139 yndL S Replication protein
NFMMICNG_03422 5.8e-74 yndM S Protein of unknown function (DUF2512)
NFMMICNG_03423 1.3e-75 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NFMMICNG_03424 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NFMMICNG_03425 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NFMMICNG_03426 5e-111 yneB L resolvase
NFMMICNG_03427 1.3e-32 ynzC S UPF0291 protein
NFMMICNG_03428 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NFMMICNG_03429 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NFMMICNG_03430 1.8e-28 yneF S UPF0154 protein
NFMMICNG_03431 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NFMMICNG_03432 7.1e-127 ccdA O cytochrome c biogenesis protein
NFMMICNG_03433 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NFMMICNG_03434 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NFMMICNG_03435 4.2e-74 yneK S Protein of unknown function (DUF2621)
NFMMICNG_03436 1.2e-64 hspX O Spore coat protein
NFMMICNG_03437 3.9e-19 sspP S Belongs to the SspP family
NFMMICNG_03438 2.2e-14 sspO S Belongs to the SspO family
NFMMICNG_03439 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NFMMICNG_03440 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NFMMICNG_03442 3.1e-08 sspN S Small acid-soluble spore protein N family
NFMMICNG_03443 3.9e-35 tlp S Belongs to the Tlp family
NFMMICNG_03444 2e-73 yneP S Thioesterase-like superfamily
NFMMICNG_03445 1.7e-53 yneQ
NFMMICNG_03446 4.1e-49 yneR S Belongs to the HesB IscA family
NFMMICNG_03447 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NFMMICNG_03448 8.6e-69 yccU S CoA-binding protein
NFMMICNG_03449 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NFMMICNG_03450 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NFMMICNG_03451 2.3e-12
NFMMICNG_03452 1.3e-57 ynfC
NFMMICNG_03453 1.8e-251 agcS E Sodium alanine symporter
NFMMICNG_03454 1.7e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NFMMICNG_03456 1.2e-249 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NFMMICNG_03457 2.4e-297 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NFMMICNG_03458 1.6e-79 yngA S membrane
NFMMICNG_03459 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NFMMICNG_03460 5.5e-104 yngC S membrane-associated protein
NFMMICNG_03461 2.6e-230 nrnB S phosphohydrolase (DHH superfamily)
NFMMICNG_03462 1.5e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NFMMICNG_03463 6.4e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NFMMICNG_03464 2.9e-165 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NFMMICNG_03465 2.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NFMMICNG_03466 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NFMMICNG_03467 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NFMMICNG_03468 1.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NFMMICNG_03469 5e-303 yngK T Glycosyl hydrolase-like 10
NFMMICNG_03470 4e-63 yngL S Protein of unknown function (DUF1360)
NFMMICNG_03471 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NFMMICNG_03472 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFMMICNG_03473 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NFMMICNG_03474 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NFMMICNG_03475 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NFMMICNG_03476 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NFMMICNG_03477 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NFMMICNG_03478 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NFMMICNG_03479 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
NFMMICNG_03480 5.6e-215 yaaH M Glycoside Hydrolase Family
NFMMICNG_03481 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NFMMICNG_03482 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NFMMICNG_03483 1.3e-09
NFMMICNG_03484 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NFMMICNG_03485 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NFMMICNG_03486 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NFMMICNG_03487 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NFMMICNG_03488 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NFMMICNG_03489 1e-181 yaaC S YaaC-like Protein
NFMMICNG_03490 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NFMMICNG_03492 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
NFMMICNG_03493 2.2e-142 ybbA S Putative esterase
NFMMICNG_03494 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFMMICNG_03495 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFMMICNG_03496 1.4e-165 feuA P Iron-uptake system-binding protein
NFMMICNG_03497 5e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NFMMICNG_03498 4.1e-239 ybbC 3.2.1.52 S protein conserved in bacteria
NFMMICNG_03499 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NFMMICNG_03500 4.2e-225 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NFMMICNG_03501 1.4e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NFMMICNG_03502 2.1e-149 ybbH K transcriptional
NFMMICNG_03503 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NFMMICNG_03504 1.9e-86 ybbJ J acetyltransferase
NFMMICNG_03505 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NFMMICNG_03511 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NFMMICNG_03512 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NFMMICNG_03513 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NFMMICNG_03514 1.5e-224 ybbR S protein conserved in bacteria
NFMMICNG_03515 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NFMMICNG_03516 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NFMMICNG_03517 1.5e-174 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NFMMICNG_03518 5.8e-120 adaA 3.2.2.21 K Transcriptional regulator
NFMMICNG_03519 1.2e-97 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NFMMICNG_03520 1.8e-276 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NFMMICNG_03521 0.0 ybcC S Belongs to the UPF0753 family
NFMMICNG_03522 4.7e-91 can 4.2.1.1 P carbonic anhydrase
NFMMICNG_03524 5.6e-46
NFMMICNG_03525 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
NFMMICNG_03526 5.1e-50 ybzH K Helix-turn-helix domain
NFMMICNG_03527 4.2e-201 ybcL EGP Major facilitator Superfamily
NFMMICNG_03529 9.1e-239 J 4Fe-4S single cluster domain
NFMMICNG_03530 1.6e-277 V CAAX protease self-immunity
NFMMICNG_03531 1.9e-135 skfE V ABC transporter
NFMMICNG_03532 4e-248 skfF S ABC transporter
NFMMICNG_03533 7.8e-91 C HEAT repeats
NFMMICNG_03534 1.1e-77 txn CO Thioredoxin-like
NFMMICNG_03535 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NFMMICNG_03536 3.8e-122 T Transcriptional regulatory protein, C terminal
NFMMICNG_03537 1.8e-168 T His Kinase A (phospho-acceptor) domain
NFMMICNG_03539 3.9e-139 KLT Protein tyrosine kinase
NFMMICNG_03540 8.5e-151 ybdN
NFMMICNG_03541 1.5e-214 ybdO S Domain of unknown function (DUF4885)
NFMMICNG_03542 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NFMMICNG_03543 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
NFMMICNG_03544 4.9e-30 ybxH S Family of unknown function (DUF5370)
NFMMICNG_03545 1.8e-150 ybxI 3.5.2.6 V beta-lactamase
NFMMICNG_03546 7.6e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NFMMICNG_03547 4.9e-41 ybyB
NFMMICNG_03548 8.8e-290 ybeC E amino acid
NFMMICNG_03549 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NFMMICNG_03550 7.3e-258 glpT G -transporter
NFMMICNG_03551 2.9e-35 S Protein of unknown function (DUF2651)
NFMMICNG_03552 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
NFMMICNG_03553 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
NFMMICNG_03555 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
NFMMICNG_03556 3.7e-160 ybfH EG EamA-like transporter family
NFMMICNG_03557 5.2e-145 msmR K AraC-like ligand binding domain
NFMMICNG_03558 2.2e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NFMMICNG_03559 2.9e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NFMMICNG_03561 1e-167 S Alpha/beta hydrolase family
NFMMICNG_03562 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NFMMICNG_03563 2.7e-85 ybfM S SNARE associated Golgi protein
NFMMICNG_03564 6.9e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NFMMICNG_03565 2e-45 ybfN
NFMMICNG_03566 6.4e-09 S Erythromycin esterase
NFMMICNG_03567 3.3e-191 yceA S Belongs to the UPF0176 family
NFMMICNG_03568 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NFMMICNG_03569 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NFMMICNG_03570 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NFMMICNG_03571 4.9e-128 K UTRA
NFMMICNG_03573 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NFMMICNG_03574 1.4e-259 mmuP E amino acid
NFMMICNG_03575 1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NFMMICNG_03576 2.8e-255 agcS E Sodium alanine symporter
NFMMICNG_03577 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
NFMMICNG_03578 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
NFMMICNG_03579 2.6e-169 glnL T Regulator
NFMMICNG_03580 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NFMMICNG_03581 3.2e-270 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NFMMICNG_03582 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NFMMICNG_03583 1.2e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NFMMICNG_03584 2.1e-123 ycbG K FCD
NFMMICNG_03585 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
NFMMICNG_03586 8.6e-167 ycbJ S Macrolide 2'-phosphotransferase
NFMMICNG_03587 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NFMMICNG_03588 5.4e-167 eamA1 EG spore germination
NFMMICNG_03589 8.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFMMICNG_03590 4.2e-167 T PhoQ Sensor
NFMMICNG_03591 3.5e-166 ycbN V ABC transporter, ATP-binding protein
NFMMICNG_03592 1.8e-114 S ABC-2 family transporter protein
NFMMICNG_03593 8.2e-53 ycbP S Protein of unknown function (DUF2512)
NFMMICNG_03594 2.8e-78 sleB 3.5.1.28 M Cell wall
NFMMICNG_03595 3.6e-134 ycbR T vWA found in TerF C terminus
NFMMICNG_03596 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NFMMICNG_03597 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NFMMICNG_03598 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NFMMICNG_03599 6.9e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NFMMICNG_03600 2.9e-199 ycbU E Selenocysteine lyase
NFMMICNG_03601 3e-225 lmrB EGP the major facilitator superfamily
NFMMICNG_03602 4.8e-102 yxaF K Transcriptional regulator
NFMMICNG_03603 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NFMMICNG_03604 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NFMMICNG_03605 4.9e-58 S RDD family
NFMMICNG_03606 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
NFMMICNG_03607 1.2e-156 2.7.13.3 T GHKL domain
NFMMICNG_03608 1.2e-126 lytR_2 T LytTr DNA-binding domain
NFMMICNG_03609 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NFMMICNG_03610 2.7e-200 natB CP ABC-2 family transporter protein
NFMMICNG_03611 1.7e-22 yccK C Aldo keto reductase
NFMMICNG_03612 1e-142 yccK C Aldo keto reductase
NFMMICNG_03613 6.6e-177 ycdA S Domain of unknown function (DUF5105)
NFMMICNG_03614 4.2e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NFMMICNG_03615 1.5e-259 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NFMMICNG_03616 2.1e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
NFMMICNG_03617 6.1e-173 S response regulator aspartate phosphatase
NFMMICNG_03618 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
NFMMICNG_03619 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NFMMICNG_03620 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
NFMMICNG_03621 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NFMMICNG_03622 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NFMMICNG_03623 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NFMMICNG_03624 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NFMMICNG_03625 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NFMMICNG_03626 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
NFMMICNG_03627 6.3e-137 terC P Protein of unknown function (DUF475)
NFMMICNG_03628 0.0 yceG S Putative component of 'biosynthetic module'
NFMMICNG_03629 2e-192 yceH P Belongs to the TelA family
NFMMICNG_03630 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
NFMMICNG_03631 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
NFMMICNG_03632 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NFMMICNG_03633 5.1e-229 proV 3.6.3.32 E glycine betaine
NFMMICNG_03634 1.3e-127 opuAB P glycine betaine
NFMMICNG_03635 1.5e-163 opuAC E glycine betaine
NFMMICNG_03636 1.9e-217 amhX S amidohydrolase
NFMMICNG_03637 1.1e-256 ycgA S Membrane
NFMMICNG_03638 4.1e-81 ycgB
NFMMICNG_03639 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NFMMICNG_03640 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NFMMICNG_03641 3e-290 lctP C L-lactate permease
NFMMICNG_03642 1.8e-260 mdr EGP Major facilitator Superfamily
NFMMICNG_03643 2.9e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
NFMMICNG_03644 2e-112 ycgF E Lysine exporter protein LysE YggA
NFMMICNG_03645 7.6e-151 yqcI S YqcI/YcgG family
NFMMICNG_03646 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NFMMICNG_03647 2.4e-112 ycgI S Domain of unknown function (DUF1989)
NFMMICNG_03648 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NFMMICNG_03649 2.5e-109 tmrB S AAA domain
NFMMICNG_03650 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NFMMICNG_03651 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
NFMMICNG_03652 1.2e-177 oxyR3 K LysR substrate binding domain
NFMMICNG_03653 9.4e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NFMMICNG_03654 4.1e-144 ycgL S Predicted nucleotidyltransferase
NFMMICNG_03655 5.1e-170 ycgM E Proline dehydrogenase
NFMMICNG_03656 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NFMMICNG_03657 2e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NFMMICNG_03658 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NFMMICNG_03659 9.1e-145 ycgQ S membrane
NFMMICNG_03660 9.1e-140 ycgR S permeases
NFMMICNG_03661 1.6e-157 I alpha/beta hydrolase fold
NFMMICNG_03662 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NFMMICNG_03663 3e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NFMMICNG_03664 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NFMMICNG_03665 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NFMMICNG_03666 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NFMMICNG_03667 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NFMMICNG_03668 1.4e-220 nasA P COG2223 Nitrate nitrite transporter
NFMMICNG_03669 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NFMMICNG_03670 5.5e-109 yciB M ErfK YbiS YcfS YnhG
NFMMICNG_03671 4.6e-227 yciC S GTPases (G3E family)
NFMMICNG_03672 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
NFMMICNG_03673 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NFMMICNG_03676 6.2e-76 yckC S membrane
NFMMICNG_03677 7.8e-52 yckD S Protein of unknown function (DUF2680)
NFMMICNG_03678 8e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NFMMICNG_03679 6.5e-69 nin S Competence protein J (ComJ)
NFMMICNG_03680 3e-70 nucA M Deoxyribonuclease NucA/NucB
NFMMICNG_03681 1.9e-186 tlpC 2.7.13.3 NT chemotaxis protein
NFMMICNG_03682 3e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NFMMICNG_03683 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NFMMICNG_03684 1.3e-63 hxlR K transcriptional
NFMMICNG_03685 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFMMICNG_03686 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFMMICNG_03687 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NFMMICNG_03688 6.4e-139 srfAD Q thioesterase
NFMMICNG_03689 6.1e-227 EGP Major Facilitator Superfamily
NFMMICNG_03690 2.3e-88 S YcxB-like protein
NFMMICNG_03691 6.4e-160 ycxC EG EamA-like transporter family
NFMMICNG_03692 5.6e-250 ycxD K GntR family transcriptional regulator
NFMMICNG_03693 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NFMMICNG_03694 1.7e-114 yczE S membrane
NFMMICNG_03695 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NFMMICNG_03696 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NFMMICNG_03697 1.3e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NFMMICNG_03698 4.9e-162 bsdA K LysR substrate binding domain
NFMMICNG_03699 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NFMMICNG_03700 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NFMMICNG_03701 4e-39 bsdD 4.1.1.61 S response to toxic substance
NFMMICNG_03702 2.3e-81 yclD
NFMMICNG_03703 1.9e-158 yclE 3.4.11.5 S Alpha beta hydrolase
NFMMICNG_03704 7.3e-267 dtpT E amino acid peptide transporter
NFMMICNG_03705 5.9e-292 yclG M Pectate lyase superfamily protein
NFMMICNG_03707 1.9e-276 gerKA EG Spore germination protein
NFMMICNG_03708 8e-227 gerKC S spore germination
NFMMICNG_03709 1e-196 gerKB F Spore germination protein
NFMMICNG_03710 5.6e-121 yclH P ABC transporter
NFMMICNG_03711 1.1e-195 yclI V ABC transporter (permease) YclI
NFMMICNG_03712 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NFMMICNG_03713 5.2e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NFMMICNG_03714 2e-70 S aspartate phosphatase
NFMMICNG_03717 5.7e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
NFMMICNG_03718 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFMMICNG_03719 1.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NFMMICNG_03720 1.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NFMMICNG_03721 1.4e-170 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NFMMICNG_03722 1.4e-251 ycnB EGP Major facilitator Superfamily
NFMMICNG_03723 7.9e-152 ycnC K Transcriptional regulator
NFMMICNG_03724 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NFMMICNG_03725 1.6e-45 ycnE S Monooxygenase
NFMMICNG_03726 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NFMMICNG_03727 5.6e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NFMMICNG_03728 2e-244 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NFMMICNG_03729 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NFMMICNG_03730 1.8e-148 glcU U Glucose uptake
NFMMICNG_03731 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFMMICNG_03732 2.9e-100 ycnI S protein conserved in bacteria
NFMMICNG_03733 4.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
NFMMICNG_03734 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NFMMICNG_03735 7.3e-56
NFMMICNG_03736 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NFMMICNG_03737 4.4e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NFMMICNG_03738 9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NFMMICNG_03739 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NFMMICNG_03740 4.1e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NFMMICNG_03741 1.3e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NFMMICNG_03742 6.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NFMMICNG_03743 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NFMMICNG_03745 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NFMMICNG_03746 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
NFMMICNG_03747 2.1e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NFMMICNG_03748 2.8e-148 ycsI S Belongs to the D-glutamate cyclase family
NFMMICNG_03749 1.2e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NFMMICNG_03750 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NFMMICNG_03751 1.2e-132 kipR K Transcriptional regulator
NFMMICNG_03752 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
NFMMICNG_03754 1.4e-49 yczJ S biosynthesis
NFMMICNG_03755 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NFMMICNG_03756 2.4e-172 ydhF S Oxidoreductase
NFMMICNG_03757 0.0 mtlR K transcriptional regulator, MtlR
NFMMICNG_03758 2.1e-293 ydaB IQ acyl-CoA ligase
NFMMICNG_03759 9e-99 ydaC Q Methyltransferase domain
NFMMICNG_03760 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NFMMICNG_03761 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NFMMICNG_03762 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NFMMICNG_03763 6.8e-77 ydaG 1.4.3.5 S general stress protein
NFMMICNG_03764 1e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NFMMICNG_03765 3.3e-46 ydzA EGP Major facilitator Superfamily
NFMMICNG_03766 2.5e-74 lrpC K Transcriptional regulator
NFMMICNG_03767 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NFMMICNG_03768 7.4e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NFMMICNG_03769 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
NFMMICNG_03770 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NFMMICNG_03771 4.5e-233 ydaM M Glycosyl transferase family group 2
NFMMICNG_03772 0.0 ydaN S Bacterial cellulose synthase subunit
NFMMICNG_03773 0.0 ydaO E amino acid
NFMMICNG_03774 1.9e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NFMMICNG_03775 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NFMMICNG_03776 2.1e-39
NFMMICNG_03777 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NFMMICNG_03779 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NFMMICNG_03780 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NFMMICNG_03782 8.9e-59 ydbB G Cupin domain
NFMMICNG_03783 3.1e-62 ydbC S Domain of unknown function (DUF4937
NFMMICNG_03784 3.5e-154 ydbD P Catalase
NFMMICNG_03785 5.1e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NFMMICNG_03786 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NFMMICNG_03787 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
NFMMICNG_03788 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NFMMICNG_03789 9.7e-181 ydbI S AI-2E family transporter
NFMMICNG_03790 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
NFMMICNG_03791 1.6e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NFMMICNG_03792 2.7e-52 ydbL
NFMMICNG_03793 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NFMMICNG_03794 1.1e-18 S Fur-regulated basic protein B
NFMMICNG_03795 2.2e-07 S Fur-regulated basic protein A
NFMMICNG_03796 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NFMMICNG_03797 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NFMMICNG_03798 3.3e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NFMMICNG_03799 5.3e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NFMMICNG_03800 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NFMMICNG_03801 2.1e-82 ydbS S Bacterial PH domain
NFMMICNG_03802 3.9e-260 ydbT S Membrane
NFMMICNG_03803 1.2e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NFMMICNG_03804 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NFMMICNG_03805 5.5e-182 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NFMMICNG_03806 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NFMMICNG_03807 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NFMMICNG_03808 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NFMMICNG_03809 3.7e-143 rsbR T Positive regulator of sigma-B
NFMMICNG_03810 5.2e-57 rsbS T antagonist
NFMMICNG_03811 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NFMMICNG_03812 9.3e-189 rsbU 3.1.3.3 KT phosphatase
NFMMICNG_03813 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
NFMMICNG_03814 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NFMMICNG_03815 1.1e-136 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NFMMICNG_03816 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NFMMICNG_03817 0.0 yhgF K COG2183 Transcriptional accessory protein
NFMMICNG_03818 2.6e-82 ydcK S Belongs to the SprT family
NFMMICNG_03826 3.2e-114 yecA E amino acid
NFMMICNG_03827 4.6e-107 K Transcriptional regulator
NFMMICNG_03828 2.5e-74 rimJ2 J Acetyltransferase (GNAT) domain
NFMMICNG_03829 8.5e-45
NFMMICNG_03830 3.3e-138 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NFMMICNG_03831 1.7e-32 K Helix-turn-helix XRE-family like proteins
NFMMICNG_03832 9.6e-40
NFMMICNG_03836 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NFMMICNG_03837 8.7e-30 cspL K Cold shock
NFMMICNG_03838 1.5e-77 carD K Transcription factor
NFMMICNG_03839 1.3e-106 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NFMMICNG_03840 2.2e-15 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NFMMICNG_03841 1.4e-164 rhaS5 K AraC-like ligand binding domain
NFMMICNG_03842 3.2e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NFMMICNG_03843 1.4e-164 ydeE K AraC family transcriptional regulator
NFMMICNG_03844 1.1e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NFMMICNG_03845 1.8e-216 ydeG EGP Major facilitator superfamily
NFMMICNG_03846 2.7e-45 ydeH
NFMMICNG_03847 2.4e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NFMMICNG_03848 1.3e-109
NFMMICNG_03849 1.1e-31 S SNARE associated Golgi protein
NFMMICNG_03850 1.8e-14 ptsH G PTS HPr component phosphorylation site
NFMMICNG_03851 3.4e-84 K Transcriptional regulator C-terminal region
NFMMICNG_03852 2e-152 ydeK EG -transporter
NFMMICNG_03853 8.7e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NFMMICNG_03854 1.3e-72 maoC I N-terminal half of MaoC dehydratase
NFMMICNG_03855 1.8e-104 ydeN S Serine hydrolase
NFMMICNG_03856 5.7e-55 K HxlR-like helix-turn-helix
NFMMICNG_03857 6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NFMMICNG_03858 1.8e-68 ydeP K Transcriptional regulator
NFMMICNG_03859 1.7e-110 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
NFMMICNG_03860 1.5e-185 ydeR EGP Major facilitator Superfamily
NFMMICNG_03861 2.5e-104 ydeS K Transcriptional regulator
NFMMICNG_03862 1.8e-56 arsR K transcriptional
NFMMICNG_03863 2.6e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NFMMICNG_03864 7.2e-149 ydfB J GNAT acetyltransferase
NFMMICNG_03865 1e-162 ydfC EG EamA-like transporter family
NFMMICNG_03866 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NFMMICNG_03867 3.8e-116 ydfE S Flavin reductase like domain
NFMMICNG_03868 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NFMMICNG_03869 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NFMMICNG_03871 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
NFMMICNG_03872 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NFMMICNG_03873 0.0 ydfJ S drug exporters of the RND superfamily
NFMMICNG_03874 1.9e-177 S Alpha/beta hydrolase family
NFMMICNG_03875 5.9e-118 S Protein of unknown function (DUF554)
NFMMICNG_03876 3.2e-147 K Bacterial transcription activator, effector binding domain
NFMMICNG_03877 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NFMMICNG_03878 9.6e-112 ydfN C nitroreductase
NFMMICNG_03879 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NFMMICNG_03880 8.8e-63 mhqP S DoxX
NFMMICNG_03881 1.3e-57 traF CO Thioredoxin
NFMMICNG_03882 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NFMMICNG_03883 6.3e-29
NFMMICNG_03885 4.4e-118 ydfR S Protein of unknown function (DUF421)
NFMMICNG_03886 5.2e-122 ydfS S Protein of unknown function (DUF421)
NFMMICNG_03887 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
NFMMICNG_03888 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
NFMMICNG_03889 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
NFMMICNG_03890 3e-94 K Bacterial regulatory proteins, tetR family
NFMMICNG_03891 1.6e-52 S DoxX-like family
NFMMICNG_03892 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
NFMMICNG_03893 5.1e-134 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NFMMICNG_03894 2e-119 purR K helix_turn _helix lactose operon repressor
NFMMICNG_03895 1e-190 csbC EGP Major facilitator Superfamily
NFMMICNG_03896 4.4e-104 G Xylose isomerase-like TIM barrel
NFMMICNG_03897 1.7e-301 expZ S ABC transporter
NFMMICNG_03898 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NFMMICNG_03899 2.3e-90 dinB S DinB family
NFMMICNG_03900 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
NFMMICNG_03901 0.0 ydgH S drug exporters of the RND superfamily
NFMMICNG_03902 8.8e-113 drgA C nitroreductase
NFMMICNG_03903 2.4e-69 ydgJ K Winged helix DNA-binding domain
NFMMICNG_03904 4.8e-208 tcaB EGP Major facilitator Superfamily
NFMMICNG_03905 1.6e-121 ydhB S membrane transporter protein
NFMMICNG_03906 6.5e-122 ydhC K FCD
NFMMICNG_03907 6.3e-243 ydhD M Glycosyl hydrolase
NFMMICNG_03908 2.9e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NFMMICNG_03909 4.2e-127
NFMMICNG_03910 2.6e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NFMMICNG_03911 8.7e-68 frataxin S Domain of unknown function (DU1801)
NFMMICNG_03913 1.5e-80 K Acetyltransferase (GNAT) domain
NFMMICNG_03914 1e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NFMMICNG_03915 2.5e-98 ydhK M Protein of unknown function (DUF1541)
NFMMICNG_03916 4.6e-200 pbuE EGP Major facilitator Superfamily
NFMMICNG_03917 4.2e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NFMMICNG_03918 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NFMMICNG_03919 9.8e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NFMMICNG_03920 7.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NFMMICNG_03921 7.4e-132 ydhQ K UTRA
NFMMICNG_03922 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NFMMICNG_03923 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
NFMMICNG_03924 9e-214 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NFMMICNG_03925 6.1e-157 ydhU P Catalase
NFMMICNG_03928 1.7e-30 csfB S Inhibitor of sigma-G Gin
NFMMICNG_03929 2.4e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NFMMICNG_03930 1.4e-201 yaaN P Belongs to the TelA family
NFMMICNG_03931 2.7e-274 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NFMMICNG_03932 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NFMMICNG_03933 2.2e-54 yaaQ S protein conserved in bacteria
NFMMICNG_03934 1.5e-71 yaaR S protein conserved in bacteria
NFMMICNG_03935 1.1e-181 holB 2.7.7.7 L DNA polymerase III
NFMMICNG_03936 6.1e-146 yaaT S stage 0 sporulation protein
NFMMICNG_03937 4.8e-31 yabA L Involved in initiation control of chromosome replication
NFMMICNG_03938 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
NFMMICNG_03939 2.8e-48 yazA L endonuclease containing a URI domain
NFMMICNG_03940 1e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NFMMICNG_03941 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NFMMICNG_03942 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NFMMICNG_03943 1.2e-143 tatD L hydrolase, TatD
NFMMICNG_03944 2e-167 rpfB GH23 T protein conserved in bacteria
NFMMICNG_03945 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NFMMICNG_03946 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NFMMICNG_03947 1.6e-136 yabG S peptidase
NFMMICNG_03948 7.8e-39 veg S protein conserved in bacteria
NFMMICNG_03949 8.3e-27 sspF S DNA topological change
NFMMICNG_03950 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NFMMICNG_03951 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NFMMICNG_03952 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NFMMICNG_03953 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NFMMICNG_03954 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NFMMICNG_03955 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NFMMICNG_03956 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NFMMICNG_03957 2.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NFMMICNG_03958 2.4e-39 yabK S Peptide ABC transporter permease
NFMMICNG_03959 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NFMMICNG_03960 1.5e-92 spoVT K stage V sporulation protein
NFMMICNG_03961 2.1e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NFMMICNG_03962 3e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NFMMICNG_03963 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NFMMICNG_03964 1.5e-49 yabP S Sporulation protein YabP
NFMMICNG_03965 2.5e-107 yabQ S spore cortex biosynthesis protein
NFMMICNG_03966 1.1e-44 divIC D Septum formation initiator
NFMMICNG_03967 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NFMMICNG_03970 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NFMMICNG_03971 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NFMMICNG_03972 3.7e-185 KLT serine threonine protein kinase
NFMMICNG_03973 4.2e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NFMMICNG_03974 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NFMMICNG_03975 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NFMMICNG_03976 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NFMMICNG_03977 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NFMMICNG_03978 4.4e-135 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NFMMICNG_03979 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NFMMICNG_03980 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NFMMICNG_03981 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NFMMICNG_03982 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NFMMICNG_03983 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NFMMICNG_03984 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NFMMICNG_03985 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NFMMICNG_03986 4.1e-30 yazB K transcriptional
NFMMICNG_03987 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NFMMICNG_03988 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NFMMICNG_03989 2.9e-76 ctsR K Belongs to the CtsR family
NFMMICNG_03990 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NFMMICNG_03991 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NFMMICNG_03992 0.0 clpC O Belongs to the ClpA ClpB family
NFMMICNG_03993 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NFMMICNG_03994 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NFMMICNG_03995 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NFMMICNG_03996 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NFMMICNG_03997 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NFMMICNG_03998 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NFMMICNG_03999 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
NFMMICNG_04000 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NFMMICNG_04001 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NFMMICNG_04002 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NFMMICNG_04003 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NFMMICNG_04004 4.4e-115 sigH K Belongs to the sigma-70 factor family
NFMMICNG_04005 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NFMMICNG_04006 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NFMMICNG_04007 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NFMMICNG_04008 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NFMMICNG_04009 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NFMMICNG_04010 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NFMMICNG_04011 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
NFMMICNG_04012 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NFMMICNG_04013 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NFMMICNG_04014 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NFMMICNG_04015 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NFMMICNG_04016 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NFMMICNG_04017 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NFMMICNG_04018 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NFMMICNG_04019 2.2e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NFMMICNG_04020 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NFMMICNG_04021 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NFMMICNG_04022 3e-105 rplD J Forms part of the polypeptide exit tunnel
NFMMICNG_04023 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NFMMICNG_04024 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NFMMICNG_04025 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NFMMICNG_04026 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NFMMICNG_04027 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NFMMICNG_04028 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NFMMICNG_04029 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NFMMICNG_04030 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NFMMICNG_04031 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NFMMICNG_04032 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NFMMICNG_04033 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NFMMICNG_04034 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NFMMICNG_04035 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NFMMICNG_04036 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NFMMICNG_04037 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NFMMICNG_04038 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NFMMICNG_04039 1.9e-23 rpmD J Ribosomal protein L30
NFMMICNG_04040 1.8e-72 rplO J binds to the 23S rRNA
NFMMICNG_04041 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NFMMICNG_04042 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NFMMICNG_04043 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NFMMICNG_04044 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NFMMICNG_04045 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NFMMICNG_04046 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NFMMICNG_04047 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NFMMICNG_04048 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NFMMICNG_04049 3.6e-58 rplQ J Ribosomal protein L17
NFMMICNG_04050 2.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NFMMICNG_04051 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NFMMICNG_04052 4e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NFMMICNG_04053 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NFMMICNG_04054 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NFMMICNG_04055 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NFMMICNG_04056 3.4e-143 ybaJ Q Methyltransferase domain
NFMMICNG_04057 9.7e-66 ybaK S Protein of unknown function (DUF2521)
NFMMICNG_04058 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NFMMICNG_04059 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NFMMICNG_04060 1.2e-84 gerD
NFMMICNG_04061 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NFMMICNG_04062 7.9e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
NFMMICNG_04063 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFMMICNG_04064 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NFMMICNG_04065 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)