ORF_ID e_value Gene_name EC_number CAZy COGs Description
JOLHEECK_00005 2e-08
JOLHEECK_00012 1.3e-09
JOLHEECK_00013 7.8e-08
JOLHEECK_00022 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JOLHEECK_00023 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JOLHEECK_00024 6.4e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
JOLHEECK_00025 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
JOLHEECK_00026 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
JOLHEECK_00027 9.9e-77 tspO T membrane
JOLHEECK_00028 1.8e-206 cotI S Spore coat protein
JOLHEECK_00029 1.8e-217 cotSA M Glycosyl transferases group 1
JOLHEECK_00030 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
JOLHEECK_00032 3.6e-235 ytcC M Glycosyltransferase Family 4
JOLHEECK_00033 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
JOLHEECK_00034 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JOLHEECK_00035 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
JOLHEECK_00036 2.6e-132 dksA T COG1734 DnaK suppressor protein
JOLHEECK_00037 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
JOLHEECK_00038 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JOLHEECK_00039 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
JOLHEECK_00040 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JOLHEECK_00041 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
JOLHEECK_00042 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
JOLHEECK_00043 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
JOLHEECK_00044 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
JOLHEECK_00045 8.8e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
JOLHEECK_00046 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
JOLHEECK_00047 1.1e-24 S Domain of Unknown Function (DUF1540)
JOLHEECK_00048 1.8e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
JOLHEECK_00049 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
JOLHEECK_00050 3.6e-41 rpmE2 J Ribosomal protein L31
JOLHEECK_00051 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
JOLHEECK_00052 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JOLHEECK_00053 2.4e-72 ytkA S YtkA-like
JOLHEECK_00055 2.1e-76 dps P Belongs to the Dps family
JOLHEECK_00056 5.4e-63 ytkC S Bacteriophage holin family
JOLHEECK_00057 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
JOLHEECK_00058 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
JOLHEECK_00059 1.4e-144 ytlC P ABC transporter
JOLHEECK_00060 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
JOLHEECK_00061 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
JOLHEECK_00062 1.2e-38 ytmB S Protein of unknown function (DUF2584)
JOLHEECK_00063 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JOLHEECK_00064 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JOLHEECK_00065 0.0 asnB 6.3.5.4 E Asparagine synthase
JOLHEECK_00066 1.1e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
JOLHEECK_00067 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JOLHEECK_00068 5.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
JOLHEECK_00069 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
JOLHEECK_00070 3.3e-106 ytqB J Putative rRNA methylase
JOLHEECK_00071 2.1e-190 yhcC S Fe-S oxidoreductase
JOLHEECK_00072 6.7e-41 ytzC S Protein of unknown function (DUF2524)
JOLHEECK_00074 5.1e-66 ytrA K GntR family transcriptional regulator
JOLHEECK_00075 4.2e-161 ytrB P abc transporter atp-binding protein
JOLHEECK_00076 8.3e-166 P ABC-2 family transporter protein
JOLHEECK_00077 5.9e-148
JOLHEECK_00078 3.1e-127 ytrE V ABC transporter, ATP-binding protein
JOLHEECK_00079 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
JOLHEECK_00080 1.1e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOLHEECK_00081 1.5e-183 T PhoQ Sensor
JOLHEECK_00082 1.1e-138 bceA V ABC transporter, ATP-binding protein
JOLHEECK_00083 0.0 bceB V ABC transporter (permease)
JOLHEECK_00084 1.3e-41 yttA 2.7.13.3 S Pfam Transposase IS66
JOLHEECK_00085 7.3e-209 yttB EGP Major facilitator Superfamily
JOLHEECK_00086 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
JOLHEECK_00087 7.7e-55 ytvB S Protein of unknown function (DUF4257)
JOLHEECK_00088 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JOLHEECK_00089 2.1e-51 ytwF P Sulfurtransferase
JOLHEECK_00090 5.8e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
JOLHEECK_00091 1.1e-142 amyC P ABC transporter (permease)
JOLHEECK_00092 1.4e-167 amyD P ABC transporter
JOLHEECK_00093 1.9e-247 msmE G Bacterial extracellular solute-binding protein
JOLHEECK_00094 1.5e-189 msmR K Transcriptional regulator
JOLHEECK_00095 7.8e-171 ytaP S Acetyl xylan esterase (AXE1)
JOLHEECK_00096 3.1e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
JOLHEECK_00097 3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
JOLHEECK_00098 1.8e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
JOLHEECK_00099 1.9e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JOLHEECK_00100 5.4e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JOLHEECK_00101 1.7e-221 bioI 1.14.14.46 C Cytochrome P450
JOLHEECK_00102 1.2e-135 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
JOLHEECK_00103 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
JOLHEECK_00104 1.8e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
JOLHEECK_00105 0.0 ytdP K Transcriptional regulator
JOLHEECK_00106 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
JOLHEECK_00107 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
JOLHEECK_00108 4.6e-73 yteS G transport
JOLHEECK_00109 2.6e-249 yteT S Oxidoreductase family, C-terminal alpha/beta domain
JOLHEECK_00110 4.8e-117 yteU S Integral membrane protein
JOLHEECK_00111 3.1e-26 yteV S Sporulation protein Cse60
JOLHEECK_00112 7.5e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
JOLHEECK_00113 1.4e-231 ytfP S HI0933-like protein
JOLHEECK_00114 3.6e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOLHEECK_00115 1.8e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JOLHEECK_00116 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
JOLHEECK_00117 9e-130 ythP V ABC transporter
JOLHEECK_00118 1.5e-203 ythQ U Bacterial ABC transporter protein EcsB
JOLHEECK_00119 7.2e-226 pbuO S permease
JOLHEECK_00120 7.1e-272 pepV 3.5.1.18 E Dipeptidase
JOLHEECK_00121 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JOLHEECK_00122 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JOLHEECK_00123 1.3e-165 ytlQ
JOLHEECK_00124 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
JOLHEECK_00125 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
JOLHEECK_00126 1e-150 ytmP 2.7.1.89 M Phosphotransferase
JOLHEECK_00127 2e-45 ytzH S YtzH-like protein
JOLHEECK_00128 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JOLHEECK_00129 1.8e-148 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
JOLHEECK_00130 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
JOLHEECK_00131 2.2e-51 ytzB S small secreted protein
JOLHEECK_00132 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
JOLHEECK_00133 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
JOLHEECK_00134 4.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JOLHEECK_00135 9.8e-149 ytpQ S Belongs to the UPF0354 family
JOLHEECK_00136 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JOLHEECK_00137 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
JOLHEECK_00138 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JOLHEECK_00139 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JOLHEECK_00140 6.6e-17 ytxH S COG4980 Gas vesicle protein
JOLHEECK_00141 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
JOLHEECK_00142 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
JOLHEECK_00143 3.8e-182 ccpA K catabolite control protein A
JOLHEECK_00144 2.1e-146 motA N flagellar motor
JOLHEECK_00145 1.4e-125 motS N Flagellar motor protein
JOLHEECK_00146 1.6e-224 acuC BQ histone deacetylase
JOLHEECK_00147 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
JOLHEECK_00148 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
JOLHEECK_00149 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
JOLHEECK_00150 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JOLHEECK_00152 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JOLHEECK_00153 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
JOLHEECK_00154 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
JOLHEECK_00155 3.4e-109 yttP K Transcriptional regulator
JOLHEECK_00156 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
JOLHEECK_00157 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JOLHEECK_00158 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
JOLHEECK_00159 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
JOLHEECK_00160 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JOLHEECK_00161 2e-29 sspB S spore protein
JOLHEECK_00162 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
JOLHEECK_00163 0.0 ytcJ S amidohydrolase
JOLHEECK_00164 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JOLHEECK_00165 7.1e-181 sppA OU signal peptide peptidase SppA
JOLHEECK_00166 1.3e-87 yteJ S RDD family
JOLHEECK_00167 5.6e-116 ytfI S Protein of unknown function (DUF2953)
JOLHEECK_00168 8.7e-70 ytfJ S Sporulation protein YtfJ
JOLHEECK_00169 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JOLHEECK_00170 7e-165 ytxK 2.1.1.72 L DNA methylase
JOLHEECK_00171 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JOLHEECK_00172 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
JOLHEECK_00173 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JOLHEECK_00174 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
JOLHEECK_00176 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOLHEECK_00177 1.7e-130 ytkL S Belongs to the UPF0173 family
JOLHEECK_00178 2.9e-173 ytlI K LysR substrate binding domain
JOLHEECK_00179 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
JOLHEECK_00180 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
JOLHEECK_00181 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
JOLHEECK_00182 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
JOLHEECK_00183 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
JOLHEECK_00184 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JOLHEECK_00185 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOLHEECK_00186 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
JOLHEECK_00187 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOLHEECK_00188 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
JOLHEECK_00189 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
JOLHEECK_00190 1.2e-158 ytnM S membrane transporter protein
JOLHEECK_00191 8e-241 ytoI K transcriptional regulator containing CBS domains
JOLHEECK_00192 2.4e-47 ytpI S YtpI-like protein
JOLHEECK_00193 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
JOLHEECK_00194 9.2e-29
JOLHEECK_00195 2.4e-68 ytrI
JOLHEECK_00196 3.2e-56 ytrH S Sporulation protein YtrH
JOLHEECK_00197 0.0 dnaE 2.7.7.7 L DNA polymerase
JOLHEECK_00198 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
JOLHEECK_00199 3.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JOLHEECK_00200 8.1e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
JOLHEECK_00201 7.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JOLHEECK_00202 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JOLHEECK_00203 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
JOLHEECK_00204 9.9e-192 ytvI S sporulation integral membrane protein YtvI
JOLHEECK_00205 4.7e-71 yeaL S membrane
JOLHEECK_00206 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
JOLHEECK_00207 1.8e-242 icd 1.1.1.42 C isocitrate
JOLHEECK_00208 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
JOLHEECK_00209 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOLHEECK_00210 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
JOLHEECK_00211 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JOLHEECK_00212 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JOLHEECK_00213 1.1e-107 ytaF P Probably functions as a manganese efflux pump
JOLHEECK_00214 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JOLHEECK_00215 8.9e-161 ytbE S reductase
JOLHEECK_00216 4.9e-205 ytbD EGP Major facilitator Superfamily
JOLHEECK_00217 9.9e-67 ytcD K Transcriptional regulator
JOLHEECK_00218 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JOLHEECK_00219 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JOLHEECK_00220 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JOLHEECK_00221 3.5e-266 dnaB L Membrane attachment protein
JOLHEECK_00222 3e-173 dnaI L Primosomal protein DnaI
JOLHEECK_00223 4.9e-111 ytxB S SNARE associated Golgi protein
JOLHEECK_00224 3.8e-159 ytxC S YtxC-like family
JOLHEECK_00225 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JOLHEECK_00226 1.5e-149 ysaA S HAD-hyrolase-like
JOLHEECK_00227 0.0 lytS 2.7.13.3 T Histidine kinase
JOLHEECK_00228 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
JOLHEECK_00229 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
JOLHEECK_00230 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
JOLHEECK_00232 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JOLHEECK_00233 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JOLHEECK_00234 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JOLHEECK_00235 7.5e-45 ysdA S Membrane
JOLHEECK_00236 9.2e-68 ysdB S Sigma-w pathway protein YsdB
JOLHEECK_00237 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
JOLHEECK_00238 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
JOLHEECK_00239 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
JOLHEECK_00240 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
JOLHEECK_00241 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
JOLHEECK_00242 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
JOLHEECK_00243 1.8e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
JOLHEECK_00244 2e-252 araN G carbohydrate transport
JOLHEECK_00245 4.2e-167 araP G carbohydrate transport
JOLHEECK_00246 3.8e-143 araQ G transport system permease
JOLHEECK_00247 1.7e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
JOLHEECK_00248 0.0 cstA T Carbon starvation protein
JOLHEECK_00249 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
JOLHEECK_00250 5.8e-255 glcF C Glycolate oxidase
JOLHEECK_00251 8.2e-260 glcD 1.1.3.15 C Glycolate oxidase subunit
JOLHEECK_00252 9.2e-206 ysfB KT regulator
JOLHEECK_00253 5.8e-32 sspI S Belongs to the SspI family
JOLHEECK_00254 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOLHEECK_00255 2.3e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JOLHEECK_00256 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JOLHEECK_00257 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JOLHEECK_00258 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JOLHEECK_00259 1.3e-85 cvpA S membrane protein, required for colicin V production
JOLHEECK_00260 0.0 polX L COG1796 DNA polymerase IV (family X)
JOLHEECK_00261 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JOLHEECK_00262 7.3e-68 yshE S membrane
JOLHEECK_00263 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JOLHEECK_00264 2.7e-100 fadR K Transcriptional regulator
JOLHEECK_00265 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
JOLHEECK_00266 4.5e-135 etfB C Electron transfer flavoprotein
JOLHEECK_00267 2.1e-177 etfA C Electron transfer flavoprotein
JOLHEECK_00269 5.7e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
JOLHEECK_00270 2e-52 trxA O Belongs to the thioredoxin family
JOLHEECK_00271 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JOLHEECK_00272 3.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
JOLHEECK_00273 1.2e-79 yslB S Protein of unknown function (DUF2507)
JOLHEECK_00274 2.4e-107 sdhC C succinate dehydrogenase
JOLHEECK_00275 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
JOLHEECK_00276 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
JOLHEECK_00277 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
JOLHEECK_00278 3.3e-30 gerE K Transcriptional regulator
JOLHEECK_00279 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
JOLHEECK_00280 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JOLHEECK_00281 2.9e-196 gerM S COG5401 Spore germination protein
JOLHEECK_00282 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JOLHEECK_00283 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JOLHEECK_00284 1.4e-92 ysnB S Phosphoesterase
JOLHEECK_00286 9.1e-134 ysnF S protein conserved in bacteria
JOLHEECK_00287 7.6e-82 ysnE K acetyltransferase
JOLHEECK_00289 0.0 ilvB 2.2.1.6 E Acetolactate synthase
JOLHEECK_00290 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
JOLHEECK_00291 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JOLHEECK_00292 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JOLHEECK_00293 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
JOLHEECK_00294 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JOLHEECK_00295 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JOLHEECK_00296 2.3e-187 ysoA H Tetratricopeptide repeat
JOLHEECK_00297 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JOLHEECK_00298 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JOLHEECK_00299 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
JOLHEECK_00300 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JOLHEECK_00301 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
JOLHEECK_00302 1.4e-89 ysxD
JOLHEECK_00303 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JOLHEECK_00304 3.6e-146 hemX O cytochrome C
JOLHEECK_00305 9.6e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
JOLHEECK_00306 7.1e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
JOLHEECK_00307 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
JOLHEECK_00308 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
JOLHEECK_00309 2.2e-222 spoVID M stage VI sporulation protein D
JOLHEECK_00310 1.7e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JOLHEECK_00311 1.6e-25
JOLHEECK_00312 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JOLHEECK_00313 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JOLHEECK_00314 8.3e-126 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
JOLHEECK_00315 8.4e-166 spoIIB S Sporulation related domain
JOLHEECK_00316 8.3e-102 maf D septum formation protein Maf
JOLHEECK_00317 1.3e-125 radC E Belongs to the UPF0758 family
JOLHEECK_00318 1.8e-184 mreB D Rod shape-determining protein MreB
JOLHEECK_00319 2.8e-157 mreC M Involved in formation and maintenance of cell shape
JOLHEECK_00320 1.4e-84 mreD M shape-determining protein
JOLHEECK_00321 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
JOLHEECK_00322 4.7e-143 minD D Belongs to the ParA family
JOLHEECK_00323 9.3e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
JOLHEECK_00324 9.2e-161 spoIVFB S Stage IV sporulation protein
JOLHEECK_00325 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
JOLHEECK_00326 4.1e-56 ysxB J ribosomal protein
JOLHEECK_00327 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JOLHEECK_00328 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
JOLHEECK_00329 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JOLHEECK_00330 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
JOLHEECK_00331 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
JOLHEECK_00332 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
JOLHEECK_00333 4.5e-227 nifS 2.8.1.7 E Cysteine desulfurase
JOLHEECK_00334 2.3e-303 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
JOLHEECK_00335 1.9e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
JOLHEECK_00336 1.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JOLHEECK_00337 8.3e-157 safA M spore coat assembly protein SafA
JOLHEECK_00338 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JOLHEECK_00339 1e-125 yebC K transcriptional regulatory protein
JOLHEECK_00340 4.5e-261 alsT E Sodium alanine symporter
JOLHEECK_00341 1.3e-50 S Family of unknown function (DUF5412)
JOLHEECK_00343 6.5e-119 yrzF T serine threonine protein kinase
JOLHEECK_00344 4.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
JOLHEECK_00345 4.5e-252 csbX EGP Major facilitator Superfamily
JOLHEECK_00346 4.8e-93 bofC S BofC C-terminal domain
JOLHEECK_00347 3.8e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JOLHEECK_00348 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JOLHEECK_00349 2.6e-18 yrzS S Protein of unknown function (DUF2905)
JOLHEECK_00350 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JOLHEECK_00351 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JOLHEECK_00352 1.1e-38 yajC U Preprotein translocase subunit YajC
JOLHEECK_00353 2.2e-73 yrzE S Protein of unknown function (DUF3792)
JOLHEECK_00354 3e-111 yrbG S membrane
JOLHEECK_00355 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOLHEECK_00356 9.4e-49 yrzD S Post-transcriptional regulator
JOLHEECK_00357 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JOLHEECK_00358 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
JOLHEECK_00359 3e-48 yrvD S Lipopolysaccharide assembly protein A domain
JOLHEECK_00360 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
JOLHEECK_00361 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JOLHEECK_00362 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JOLHEECK_00363 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JOLHEECK_00364 1.5e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
JOLHEECK_00366 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
JOLHEECK_00367 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JOLHEECK_00368 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
JOLHEECK_00369 4.4e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
JOLHEECK_00370 1.2e-70 cymR K Transcriptional regulator
JOLHEECK_00371 1.4e-212 iscS 2.8.1.7 E Cysteine desulfurase
JOLHEECK_00372 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JOLHEECK_00373 1.4e-15 S COG0457 FOG TPR repeat
JOLHEECK_00374 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JOLHEECK_00375 2.5e-80 yrrD S protein conserved in bacteria
JOLHEECK_00376 9.8e-31 yrzR
JOLHEECK_00377 8e-08 S Protein of unknown function (DUF3918)
JOLHEECK_00378 7.6e-107 glnP P ABC transporter
JOLHEECK_00379 8e-109 gluC P ABC transporter
JOLHEECK_00380 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
JOLHEECK_00381 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JOLHEECK_00382 2.7e-170 yrrI S AI-2E family transporter
JOLHEECK_00383 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JOLHEECK_00384 1.7e-41 yrzL S Belongs to the UPF0297 family
JOLHEECK_00385 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JOLHEECK_00386 1.2e-45 yrzB S Belongs to the UPF0473 family
JOLHEECK_00387 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JOLHEECK_00388 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
JOLHEECK_00389 3.9e-173 yegQ O Peptidase U32
JOLHEECK_00390 2.7e-246 yegQ O COG0826 Collagenase and related proteases
JOLHEECK_00391 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
JOLHEECK_00392 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JOLHEECK_00393 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
JOLHEECK_00394 2.5e-60 yrrS S Protein of unknown function (DUF1510)
JOLHEECK_00395 1e-25 yrzA S Protein of unknown function (DUF2536)
JOLHEECK_00396 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
JOLHEECK_00397 1.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JOLHEECK_00398 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
JOLHEECK_00399 1.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JOLHEECK_00400 4.6e-35 yrhC S YrhC-like protein
JOLHEECK_00401 1.4e-78 yrhD S Protein of unknown function (DUF1641)
JOLHEECK_00402 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
JOLHEECK_00403 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
JOLHEECK_00404 1.8e-142 focA P Formate nitrite
JOLHEECK_00407 7.2e-95 yrhH Q methyltransferase
JOLHEECK_00408 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
JOLHEECK_00409 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
JOLHEECK_00410 4.3e-168 capL C PFAM UDP-glucose GDP-mannose dehydrogenase
JOLHEECK_00411 2.6e-119 wbpP 5.1.3.2, 5.1.3.7 GM NmrA-like family
JOLHEECK_00412 9.4e-117 S ATPases associated with a variety of cellular activities
JOLHEECK_00413 5.7e-64 S ABC-2 family transporter protein
JOLHEECK_00414 8.3e-63 S ABC-2 family transporter protein
JOLHEECK_00415 7.2e-104 Q TIGRFAM amino acid adenylation domain
JOLHEECK_00416 2e-46 hopR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
JOLHEECK_00417 1.5e-180 hutH 4.3.1.23, 4.3.1.24, 4.3.1.3, 5.4.3.6 E Aromatic amino acid lyase
JOLHEECK_00418 1.2e-100 EF ATP-grasp domain
JOLHEECK_00419 6.6e-88 yodQ 3.5.1.16 E Acetylornithine deacetylase
JOLHEECK_00420 1.5e-52 S dehydrogenases and related proteins
JOLHEECK_00421 3.9e-11 O Butirosin biosynthesis protein H, N-terminal
JOLHEECK_00422 7.3e-29 S Butirosin biosynthesis protein H, N-terminal
JOLHEECK_00423 1e-18 yrhK S YrhK-like protein
JOLHEECK_00424 0.0 yrhL I Acyltransferase family
JOLHEECK_00425 3.8e-151 rsiV S Protein of unknown function (DUF3298)
JOLHEECK_00426 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
JOLHEECK_00427 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
JOLHEECK_00428 3.6e-106 yrhP E LysE type translocator
JOLHEECK_00429 1e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
JOLHEECK_00430 0.0 levR K PTS system fructose IIA component
JOLHEECK_00431 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
JOLHEECK_00432 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
JOLHEECK_00433 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
JOLHEECK_00434 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
JOLHEECK_00435 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
JOLHEECK_00436 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
JOLHEECK_00437 3.2e-200 adhA 1.1.1.1 C alcohol dehydrogenase
JOLHEECK_00438 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
JOLHEECK_00439 4.3e-47 yraB K helix_turn_helix, mercury resistance
JOLHEECK_00440 1.1e-49 yraD M Spore coat protein
JOLHEECK_00441 2.6e-26 yraE
JOLHEECK_00442 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
JOLHEECK_00443 6.4e-63 yraF M Spore coat protein
JOLHEECK_00444 5.3e-37 yraG
JOLHEECK_00445 1.3e-66 E Glyoxalase-like domain
JOLHEECK_00446 2.4e-61 T sh3 domain protein
JOLHEECK_00447 1.7e-60 T sh3 domain protein
JOLHEECK_00448 3.2e-155 S Alpha beta hydrolase
JOLHEECK_00449 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOLHEECK_00450 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
JOLHEECK_00452 1.6e-205 yraM S PrpF protein
JOLHEECK_00453 3.4e-163 yraN K Transcriptional regulator
JOLHEECK_00454 3.4e-223 yraO C Citrate transporter
JOLHEECK_00455 1.3e-187 yrpG C Aldo/keto reductase family
JOLHEECK_00456 2.4e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
JOLHEECK_00457 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
JOLHEECK_00459 1.6e-123 yrpD S Domain of unknown function, YrpD
JOLHEECK_00460 4.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JOLHEECK_00461 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
JOLHEECK_00462 4.2e-166 aadK G Streptomycin adenylyltransferase
JOLHEECK_00463 2.4e-89 yrdA S DinB family
JOLHEECK_00464 3.3e-57 S Protein of unknown function (DUF2568)
JOLHEECK_00465 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
JOLHEECK_00466 1.1e-40 yrdF K ribonuclease inhibitor
JOLHEECK_00467 5.3e-78 bkdR K helix_turn_helix ASNC type
JOLHEECK_00468 9.6e-138 azlC E AzlC protein
JOLHEECK_00469 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
JOLHEECK_00470 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
JOLHEECK_00471 5e-162 gltR K LysR substrate binding domain
JOLHEECK_00472 1.3e-66 yodA S tautomerase
JOLHEECK_00473 4e-149 czcD P COG1230 Co Zn Cd efflux system component
JOLHEECK_00474 2.3e-198 trkA P Oxidoreductase
JOLHEECK_00475 3e-159 yrdQ K Transcriptional regulator
JOLHEECK_00476 1.6e-169 yrdR EG EamA-like transporter family
JOLHEECK_00477 3.9e-16 S YrzO-like protein
JOLHEECK_00478 2.5e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JOLHEECK_00479 5.9e-82 bltD 2.3.1.57 K FR47-like protein
JOLHEECK_00480 3.9e-210 blt EGP Major facilitator Superfamily
JOLHEECK_00481 4.2e-147 bltR K helix_turn_helix, mercury resistance
JOLHEECK_00482 5.5e-106 yrkC G Cupin domain
JOLHEECK_00483 7.8e-39 yrkD S protein conserved in bacteria
JOLHEECK_00484 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
JOLHEECK_00485 2.3e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
JOLHEECK_00486 9.3e-206 yrkH P Rhodanese Homology Domain
JOLHEECK_00487 3.5e-35 yrkI O Belongs to the sulfur carrier protein TusA family
JOLHEECK_00488 5.4e-112 yrkJ S membrane transporter protein
JOLHEECK_00489 7e-166 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
JOLHEECK_00490 2e-215 mepA V Multidrug transporter MatE
JOLHEECK_00491 3.6e-112 tetR3 K Transcriptional regulator
JOLHEECK_00492 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOLHEECK_00493 1.2e-94 yqaB E IrrE N-terminal-like domain
JOLHEECK_00495 1.2e-97 adk 2.7.4.3 F adenylate kinase activity
JOLHEECK_00497 1.1e-32 K sequence-specific DNA binding
JOLHEECK_00498 1.2e-17 K Helix-turn-helix XRE-family like proteins
JOLHEECK_00500 1.2e-103
JOLHEECK_00504 1.4e-162 yqaJ L YqaJ-like viral recombinase domain
JOLHEECK_00505 2.5e-155 recT L RecT family
JOLHEECK_00506 1e-122 3.1.3.16 L DnaD domain protein
JOLHEECK_00507 5.9e-168 xkdC L IstB-like ATP binding protein
JOLHEECK_00509 7.2e-74 rusA L Endodeoxyribonuclease RusA
JOLHEECK_00510 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
JOLHEECK_00511 1.6e-166
JOLHEECK_00512 6.5e-81 L Transposase
JOLHEECK_00514 6.3e-107 yqaS L DNA packaging
JOLHEECK_00515 2.4e-253 S phage terminase, large subunit
JOLHEECK_00516 3.3e-286 yqbA S portal protein
JOLHEECK_00517 1.4e-151 S Phage Mu protein F like protein
JOLHEECK_00518 6.1e-63
JOLHEECK_00519 2.8e-118 yqbD 2.1.1.72 L Putative phage serine protease XkdF
JOLHEECK_00520 7.1e-167 xkdG S Phage capsid family
JOLHEECK_00521 1.6e-46 S YqbF, hypothetical protein domain
JOLHEECK_00522 3.9e-66 S Protein of unknown function (DUF3199)
JOLHEECK_00523 1.2e-61 yqbH S Domain of unknown function (DUF3599)
JOLHEECK_00524 3.3e-86 S Bacteriophage HK97-gp10, putative tail-component
JOLHEECK_00525 7.8e-76
JOLHEECK_00526 1.8e-24
JOLHEECK_00527 6.3e-252 xkdK S Phage tail sheath C-terminal domain
JOLHEECK_00528 3.6e-76 xkdM S Phage tail tube protein
JOLHEECK_00529 1.2e-66 S Phage XkdN-like tail assembly chaperone protein, TAC
JOLHEECK_00530 0.0 xkdO L Transglycosylase SLT domain
JOLHEECK_00531 7.6e-113 xkdP S Lysin motif
JOLHEECK_00532 4.2e-178 yqbQ 3.2.1.96 G NLP P60 protein
JOLHEECK_00533 2.7e-31 xkdR S Protein of unknown function (DUF2577)
JOLHEECK_00534 1.9e-66 xkdS S Protein of unknown function (DUF2634)
JOLHEECK_00535 5.5e-184 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
JOLHEECK_00536 7.1e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
JOLHEECK_00537 9.6e-40
JOLHEECK_00538 4.2e-219
JOLHEECK_00539 4.1e-56 xkdW S XkdW protein
JOLHEECK_00540 3.7e-10
JOLHEECK_00541 3e-159 xepA
JOLHEECK_00542 2.6e-68 S Bacteriophage holin family
JOLHEECK_00543 5.9e-133 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JOLHEECK_00546 4.6e-100 S Suppressor of fused protein (SUFU)
JOLHEECK_00547 3.7e-47
JOLHEECK_00548 1.3e-14 S SMI1-KNR4 cell-wall
JOLHEECK_00550 1.1e-26 yokK S SMI1 / KNR4 family
JOLHEECK_00551 6e-228 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
JOLHEECK_00552 1e-70 K MerR family transcriptional regulator
JOLHEECK_00553 1.3e-138 yvgN 1.1.1.346 S Reductase
JOLHEECK_00554 8.4e-130 S Aspartate phosphatase response regulator
JOLHEECK_00556 1.3e-123 yecA E amino acid
JOLHEECK_00557 1.5e-105 K Transcriptional regulator
JOLHEECK_00558 4.6e-277 cisA2 L Recombinase
JOLHEECK_00559 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOLHEECK_00560 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
JOLHEECK_00561 2e-132 yqeB
JOLHEECK_00562 1.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
JOLHEECK_00563 2.3e-105 yqeD S SNARE associated Golgi protein
JOLHEECK_00564 1.7e-131 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOLHEECK_00565 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
JOLHEECK_00567 5.3e-95 yqeG S hydrolase of the HAD superfamily
JOLHEECK_00568 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
JOLHEECK_00569 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JOLHEECK_00570 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
JOLHEECK_00571 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JOLHEECK_00572 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
JOLHEECK_00573 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JOLHEECK_00574 2.9e-139 yqeM Q Methyltransferase
JOLHEECK_00575 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JOLHEECK_00576 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
JOLHEECK_00577 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
JOLHEECK_00578 0.0 comEC S Competence protein ComEC
JOLHEECK_00579 4.1e-15 S YqzM-like protein
JOLHEECK_00580 5.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
JOLHEECK_00581 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
JOLHEECK_00582 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JOLHEECK_00583 4.5e-222 spoIIP M stage II sporulation protein P
JOLHEECK_00584 7.2e-53 yqxA S Protein of unknown function (DUF3679)
JOLHEECK_00585 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JOLHEECK_00586 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
JOLHEECK_00587 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JOLHEECK_00588 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JOLHEECK_00589 0.0 dnaK O Heat shock 70 kDa protein
JOLHEECK_00590 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JOLHEECK_00591 6e-174 prmA J Methylates ribosomal protein L11
JOLHEECK_00592 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JOLHEECK_00593 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
JOLHEECK_00594 2.3e-157 yqeW P COG1283 Na phosphate symporter
JOLHEECK_00595 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JOLHEECK_00596 2.5e-61 yqeY S Yqey-like protein
JOLHEECK_00597 7.7e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
JOLHEECK_00598 4.3e-122 yqfA S UPF0365 protein
JOLHEECK_00599 2.4e-21 yqfB
JOLHEECK_00600 2.7e-45 yqfC S sporulation protein YqfC
JOLHEECK_00601 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
JOLHEECK_00602 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
JOLHEECK_00604 0.0 yqfF S membrane-associated HD superfamily hydrolase
JOLHEECK_00605 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JOLHEECK_00606 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JOLHEECK_00607 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
JOLHEECK_00608 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JOLHEECK_00609 8.4e-19 S YqzL-like protein
JOLHEECK_00610 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
JOLHEECK_00611 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JOLHEECK_00612 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JOLHEECK_00613 4.5e-112 ccpN K CBS domain
JOLHEECK_00614 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
JOLHEECK_00615 4.5e-88 yaiI S Belongs to the UPF0178 family
JOLHEECK_00616 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JOLHEECK_00617 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JOLHEECK_00618 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
JOLHEECK_00619 1.5e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
JOLHEECK_00620 5.3e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JOLHEECK_00621 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JOLHEECK_00622 3.5e-12 yqfQ S YqfQ-like protein
JOLHEECK_00623 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JOLHEECK_00624 2.6e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JOLHEECK_00625 7.9e-36 yqfT S Protein of unknown function (DUF2624)
JOLHEECK_00626 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
JOLHEECK_00627 1.9e-77 zur P Belongs to the Fur family
JOLHEECK_00628 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
JOLHEECK_00629 4.3e-62 yqfX S membrane
JOLHEECK_00630 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JOLHEECK_00631 5.2e-47 yqfZ M LysM domain
JOLHEECK_00632 3.9e-131 yqgB S Protein of unknown function (DUF1189)
JOLHEECK_00633 4e-73 yqgC S protein conserved in bacteria
JOLHEECK_00634 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
JOLHEECK_00635 2.5e-231 yqgE EGP Major facilitator superfamily
JOLHEECK_00636 0.0 pbpA 3.4.16.4 M penicillin-binding protein
JOLHEECK_00637 3.4e-150 pstS P Phosphate
JOLHEECK_00638 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
JOLHEECK_00639 4.4e-158 pstA P Phosphate transport system permease
JOLHEECK_00640 3.2e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JOLHEECK_00641 8.3e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JOLHEECK_00642 2.1e-71 yqzC S YceG-like family
JOLHEECK_00643 3.5e-50 yqzD
JOLHEECK_00645 1.5e-41 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
JOLHEECK_00646 4.1e-133 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
JOLHEECK_00647 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JOLHEECK_00648 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JOLHEECK_00649 2.5e-09 yqgO
JOLHEECK_00650 4e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
JOLHEECK_00651 3.1e-33 yqgQ S Protein conserved in bacteria
JOLHEECK_00652 5.2e-181 glcK 2.7.1.2 G Glucokinase
JOLHEECK_00653 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JOLHEECK_00654 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
JOLHEECK_00655 2.7e-199 yqgU
JOLHEECK_00656 6.9e-50 yqgV S Thiamine-binding protein
JOLHEECK_00657 8.9e-23 yqgW S Protein of unknown function (DUF2759)
JOLHEECK_00658 9.5e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
JOLHEECK_00659 1.8e-37 yqgY S Protein of unknown function (DUF2626)
JOLHEECK_00660 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
JOLHEECK_00662 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JOLHEECK_00663 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JOLHEECK_00664 1.4e-173 corA P Mg2 transporter protein
JOLHEECK_00667 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JOLHEECK_00668 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
JOLHEECK_00669 6.8e-47 comGC U Required for transformation and DNA binding
JOLHEECK_00670 6.3e-70 gspH NU protein transport across the cell outer membrane
JOLHEECK_00671 2e-58 comGE
JOLHEECK_00672 1.7e-34 comGF U Putative Competence protein ComGF
JOLHEECK_00673 8.8e-44 S ComG operon protein 7
JOLHEECK_00674 4.4e-25 yqzE S YqzE-like protein
JOLHEECK_00675 7.3e-54 yqzG S Protein of unknown function (DUF3889)
JOLHEECK_00676 2.8e-113 yqxM
JOLHEECK_00677 2.5e-58 sipW 3.4.21.89 U Signal peptidase
JOLHEECK_00678 1.9e-141 tasA S Cell division protein FtsN
JOLHEECK_00679 1e-54 sinR K transcriptional
JOLHEECK_00680 1.2e-24 sinI S Anti-repressor SinI
JOLHEECK_00681 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
JOLHEECK_00682 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
JOLHEECK_00683 1.8e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
JOLHEECK_00684 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JOLHEECK_00685 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JOLHEECK_00686 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
JOLHEECK_00687 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
JOLHEECK_00688 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
JOLHEECK_00689 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
JOLHEECK_00690 2.2e-61 yqhP
JOLHEECK_00691 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
JOLHEECK_00692 2.3e-93 yqhR S Conserved membrane protein YqhR
JOLHEECK_00693 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
JOLHEECK_00694 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
JOLHEECK_00695 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JOLHEECK_00696 7.9e-37 yqhV S Protein of unknown function (DUF2619)
JOLHEECK_00697 1e-170 spoIIIAA S stage III sporulation protein AA
JOLHEECK_00698 1.1e-84 spoIIIAB S Stage III sporulation protein
JOLHEECK_00699 7.6e-29 spoIIIAC S stage III sporulation protein AC
JOLHEECK_00700 2.3e-58 spoIIIAD S Stage III sporulation protein AD
JOLHEECK_00701 2.9e-197 spoIIIAE S stage III sporulation protein AE
JOLHEECK_00702 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
JOLHEECK_00703 6.5e-109 spoIIIAG S stage III sporulation protein AG
JOLHEECK_00704 9.9e-91 spoIIIAH S SpoIIIAH-like protein
JOLHEECK_00705 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JOLHEECK_00706 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
JOLHEECK_00707 2.1e-67 yqhY S protein conserved in bacteria
JOLHEECK_00708 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JOLHEECK_00709 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JOLHEECK_00710 1.1e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JOLHEECK_00711 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JOLHEECK_00712 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JOLHEECK_00713 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JOLHEECK_00714 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
JOLHEECK_00715 1.7e-78 argR K Regulates arginine biosynthesis genes
JOLHEECK_00716 0.0 recN L May be involved in recombinational repair of damaged DNA
JOLHEECK_00717 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
JOLHEECK_00718 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
JOLHEECK_00720 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
JOLHEECK_00721 5.9e-27
JOLHEECK_00722 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
JOLHEECK_00723 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JOLHEECK_00724 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
JOLHEECK_00725 2.3e-156 hbdA 1.1.1.157 I Dehydrogenase
JOLHEECK_00726 8.8e-212 mmgC I acyl-CoA dehydrogenase
JOLHEECK_00727 8.4e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
JOLHEECK_00728 2.4e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
JOLHEECK_00729 6.9e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JOLHEECK_00730 4e-34 yqzF S Protein of unknown function (DUF2627)
JOLHEECK_00731 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
JOLHEECK_00732 2.3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
JOLHEECK_00733 1.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
JOLHEECK_00734 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
JOLHEECK_00735 2.8e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JOLHEECK_00736 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JOLHEECK_00737 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JOLHEECK_00738 5.4e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JOLHEECK_00739 6.4e-151 bmrR K helix_turn_helix, mercury resistance
JOLHEECK_00740 5.1e-207 norA EGP Major facilitator Superfamily
JOLHEECK_00741 9.8e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JOLHEECK_00742 9.3e-77 yqiW S Belongs to the UPF0403 family
JOLHEECK_00743 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
JOLHEECK_00744 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
JOLHEECK_00745 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JOLHEECK_00746 7.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
JOLHEECK_00747 1.4e-98 yqjB S protein conserved in bacteria
JOLHEECK_00749 8.7e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
JOLHEECK_00750 3.8e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
JOLHEECK_00751 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
JOLHEECK_00752 2.6e-140 yqjF S Uncharacterized conserved protein (COG2071)
JOLHEECK_00753 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JOLHEECK_00754 4.5e-24 yqzJ
JOLHEECK_00755 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JOLHEECK_00756 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JOLHEECK_00757 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JOLHEECK_00758 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JOLHEECK_00759 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JOLHEECK_00760 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JOLHEECK_00761 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
JOLHEECK_00762 0.0 rocB E arginine degradation protein
JOLHEECK_00763 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JOLHEECK_00764 4.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
JOLHEECK_00765 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
JOLHEECK_00766 9.3e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
JOLHEECK_00767 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
JOLHEECK_00768 4.7e-08 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOLHEECK_00769 1.1e-42 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOLHEECK_00771 6.1e-222 yqjV G Major Facilitator Superfamily
JOLHEECK_00773 9.2e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JOLHEECK_00774 2.2e-49 S YolD-like protein
JOLHEECK_00775 1.8e-86 yqjY K acetyltransferase
JOLHEECK_00776 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
JOLHEECK_00777 7.5e-194 yqkA K GrpB protein
JOLHEECK_00778 2.8e-54 yqkB S Belongs to the HesB IscA family
JOLHEECK_00779 9.4e-39 yqkC S Protein of unknown function (DUF2552)
JOLHEECK_00780 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
JOLHEECK_00781 3.1e-12 yqkE S Protein of unknown function (DUF3886)
JOLHEECK_00782 4.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
JOLHEECK_00784 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
JOLHEECK_00785 1.4e-220 yqxK 3.6.4.12 L DNA helicase
JOLHEECK_00786 4.5e-58 ansR K Transcriptional regulator
JOLHEECK_00787 2.3e-184 ansA 3.5.1.1 EJ L-asparaginase
JOLHEECK_00788 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
JOLHEECK_00789 2.7e-234 mleN C Na H antiporter
JOLHEECK_00790 5.5e-242 mleA 1.1.1.38 C malic enzyme
JOLHEECK_00791 5.5e-30 yqkK
JOLHEECK_00792 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
JOLHEECK_00793 2.4e-80 fur P Belongs to the Fur family
JOLHEECK_00794 3.7e-37 S Protein of unknown function (DUF4227)
JOLHEECK_00795 2.6e-166 xerD L recombinase XerD
JOLHEECK_00796 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JOLHEECK_00797 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JOLHEECK_00798 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
JOLHEECK_00799 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
JOLHEECK_00800 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
JOLHEECK_00801 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOLHEECK_00802 7.4e-112 spoVAA S Stage V sporulation protein AA
JOLHEECK_00803 1e-67 spoVAB S Stage V sporulation protein AB
JOLHEECK_00804 2.3e-78 spoVAC S stage V sporulation protein AC
JOLHEECK_00805 9e-192 spoVAD I Stage V sporulation protein AD
JOLHEECK_00806 2.2e-57 spoVAEB S stage V sporulation protein
JOLHEECK_00807 1.4e-110 spoVAEA S stage V sporulation protein
JOLHEECK_00808 1.4e-273 spoVAF EG Stage V sporulation protein AF
JOLHEECK_00809 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JOLHEECK_00810 3.6e-149 ypuA S Secreted protein
JOLHEECK_00811 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JOLHEECK_00814 3.4e-13 S PAP2 superfamily
JOLHEECK_00815 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
JOLHEECK_00816 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JOLHEECK_00817 7.8e-55 ypuD
JOLHEECK_00818 2.4e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JOLHEECK_00819 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
JOLHEECK_00820 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JOLHEECK_00821 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
JOLHEECK_00822 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOLHEECK_00823 1.4e-92 ypuF S Domain of unknown function (DUF309)
JOLHEECK_00824 2.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JOLHEECK_00825 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JOLHEECK_00826 7.6e-97 ypuI S Protein of unknown function (DUF3907)
JOLHEECK_00827 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
JOLHEECK_00828 3.5e-103 spmA S Spore maturation protein
JOLHEECK_00829 1.9e-87 spmB S Spore maturation protein
JOLHEECK_00830 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JOLHEECK_00831 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
JOLHEECK_00832 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
JOLHEECK_00833 9.7e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
JOLHEECK_00834 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOLHEECK_00835 0.0 resE 2.7.13.3 T Histidine kinase
JOLHEECK_00836 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
JOLHEECK_00837 7.3e-195 rsiX
JOLHEECK_00838 2.2e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JOLHEECK_00839 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOLHEECK_00840 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JOLHEECK_00841 4.7e-41 fer C Ferredoxin
JOLHEECK_00842 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
JOLHEECK_00843 3.2e-286 recQ 3.6.4.12 L DNA helicase
JOLHEECK_00844 2.2e-100 ypbD S metal-dependent membrane protease
JOLHEECK_00845 4.6e-81 ypbE M Lysin motif
JOLHEECK_00846 2.8e-81 ypbF S Protein of unknown function (DUF2663)
JOLHEECK_00847 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
JOLHEECK_00848 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
JOLHEECK_00849 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
JOLHEECK_00850 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
JOLHEECK_00851 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
JOLHEECK_00852 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
JOLHEECK_00853 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
JOLHEECK_00854 9.2e-113 ypfA M Flagellar protein YcgR
JOLHEECK_00855 1.8e-23 S Family of unknown function (DUF5359)
JOLHEECK_00856 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JOLHEECK_00857 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
JOLHEECK_00858 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JOLHEECK_00859 1e-07 S YpzI-like protein
JOLHEECK_00860 1.3e-102 yphA
JOLHEECK_00861 2.5e-161 seaA S YIEGIA protein
JOLHEECK_00862 1.6e-28 ypzH
JOLHEECK_00863 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JOLHEECK_00864 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JOLHEECK_00865 1.6e-18 yphE S Protein of unknown function (DUF2768)
JOLHEECK_00866 5.4e-138 yphF
JOLHEECK_00867 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JOLHEECK_00868 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JOLHEECK_00869 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
JOLHEECK_00870 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
JOLHEECK_00871 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
JOLHEECK_00872 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
JOLHEECK_00873 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JOLHEECK_00874 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
JOLHEECK_00875 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
JOLHEECK_00876 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JOLHEECK_00877 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JOLHEECK_00878 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
JOLHEECK_00879 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JOLHEECK_00880 3.9e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JOLHEECK_00881 8.1e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
JOLHEECK_00882 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
JOLHEECK_00883 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JOLHEECK_00884 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
JOLHEECK_00885 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JOLHEECK_00886 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
JOLHEECK_00887 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
JOLHEECK_00888 4.1e-234 S COG0457 FOG TPR repeat
JOLHEECK_00889 1.1e-98 ypiB S Belongs to the UPF0302 family
JOLHEECK_00890 4.2e-77 ypiF S Protein of unknown function (DUF2487)
JOLHEECK_00891 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
JOLHEECK_00892 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
JOLHEECK_00893 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
JOLHEECK_00894 7.6e-98 ypjA S membrane
JOLHEECK_00895 1e-142 ypjB S sporulation protein
JOLHEECK_00896 5.2e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
JOLHEECK_00897 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
JOLHEECK_00898 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JOLHEECK_00899 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
JOLHEECK_00900 1.7e-128 bshB1 S proteins, LmbE homologs
JOLHEECK_00901 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
JOLHEECK_00902 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JOLHEECK_00903 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JOLHEECK_00904 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
JOLHEECK_00905 6.1e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JOLHEECK_00906 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JOLHEECK_00907 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JOLHEECK_00908 1.9e-22 ypmA S Protein of unknown function (DUF4264)
JOLHEECK_00909 4.9e-79 ypmB S protein conserved in bacteria
JOLHEECK_00910 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
JOLHEECK_00911 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
JOLHEECK_00912 1.3e-128 dnaD L DNA replication protein DnaD
JOLHEECK_00913 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JOLHEECK_00914 1.8e-92 ypoC
JOLHEECK_00915 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
JOLHEECK_00916 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JOLHEECK_00917 5.4e-186 yppC S Protein of unknown function (DUF2515)
JOLHEECK_00920 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
JOLHEECK_00922 6.6e-47 yppG S YppG-like protein
JOLHEECK_00923 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
JOLHEECK_00924 1.2e-80 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
JOLHEECK_00925 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
JOLHEECK_00926 2.5e-236 yprB L RNase_H superfamily
JOLHEECK_00927 8.2e-91 ypsA S Belongs to the UPF0398 family
JOLHEECK_00928 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JOLHEECK_00929 1.2e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JOLHEECK_00931 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
JOLHEECK_00932 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOLHEECK_00933 1.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JOLHEECK_00934 7.4e-186 ptxS K transcriptional
JOLHEECK_00935 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
JOLHEECK_00936 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
JOLHEECK_00937 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
JOLHEECK_00938 3.9e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JOLHEECK_00939 4.4e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JOLHEECK_00940 3.8e-227 pbuX F xanthine
JOLHEECK_00941 8.2e-207 bcsA Q Naringenin-chalcone synthase
JOLHEECK_00942 7.4e-86 ypbQ S protein conserved in bacteria
JOLHEECK_00944 0.0 ypbR S Dynamin family
JOLHEECK_00945 8.5e-38 ypbS S Protein of unknown function (DUF2533)
JOLHEECK_00946 2e-07
JOLHEECK_00947 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
JOLHEECK_00949 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
JOLHEECK_00950 4.5e-106 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JOLHEECK_00951 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
JOLHEECK_00952 2.6e-27 ypeQ S Zinc-finger
JOLHEECK_00953 1.8e-30 S Protein of unknown function (DUF2564)
JOLHEECK_00954 3.8e-16 degR
JOLHEECK_00955 7.9e-31 cspD K Cold-shock protein
JOLHEECK_00956 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
JOLHEECK_00957 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JOLHEECK_00958 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
JOLHEECK_00959 5.4e-107 ypgQ S phosphohydrolase
JOLHEECK_00960 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
JOLHEECK_00961 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JOLHEECK_00962 1.7e-75 yphP S Belongs to the UPF0403 family
JOLHEECK_00963 3.7e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
JOLHEECK_00964 7.8e-114 ypjP S YpjP-like protein
JOLHEECK_00965 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
JOLHEECK_00966 1.5e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JOLHEECK_00967 1.6e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JOLHEECK_00968 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
JOLHEECK_00969 4.2e-110 hlyIII S protein, Hemolysin III
JOLHEECK_00970 1.6e-185 pspF K Transcriptional regulator
JOLHEECK_00971 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JOLHEECK_00972 3.1e-40 ypmP S Protein of unknown function (DUF2535)
JOLHEECK_00973 2.7e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
JOLHEECK_00974 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
JOLHEECK_00975 1.1e-98 ypmS S protein conserved in bacteria
JOLHEECK_00976 5.5e-29 ypmT S Uncharacterized ympT
JOLHEECK_00977 3.8e-222 mepA V MATE efflux family protein
JOLHEECK_00978 1.6e-70 ypoP K transcriptional
JOLHEECK_00979 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JOLHEECK_00980 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
JOLHEECK_00981 1.3e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
JOLHEECK_00982 5.2e-212 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
JOLHEECK_00983 2e-185 cgeB S Spore maturation protein
JOLHEECK_00984 1.2e-65 cgeA
JOLHEECK_00985 3.5e-38 cgeC
JOLHEECK_00986 1e-256 cgeD M maturation of the outermost layer of the spore
JOLHEECK_00987 8.3e-145 yiiD K acetyltransferase
JOLHEECK_00989 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JOLHEECK_00990 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JOLHEECK_00991 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
JOLHEECK_00992 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
JOLHEECK_00993 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
JOLHEECK_00994 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
JOLHEECK_00995 2.9e-47 yokU S YokU-like protein, putative antitoxin
JOLHEECK_00996 1.4e-36 yozE S Belongs to the UPF0346 family
JOLHEECK_00997 1.4e-124 yodN
JOLHEECK_00999 2.8e-24 yozD S YozD-like protein
JOLHEECK_01000 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
JOLHEECK_01001 3.6e-54 yodL S YodL-like
JOLHEECK_01002 5.3e-09
JOLHEECK_01003 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
JOLHEECK_01004 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
JOLHEECK_01005 5.2e-24 yodI
JOLHEECK_01006 1.7e-128 yodH Q Methyltransferase
JOLHEECK_01007 1.6e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
JOLHEECK_01008 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOLHEECK_01009 6.2e-28 S Protein of unknown function (DUF3311)
JOLHEECK_01010 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
JOLHEECK_01011 3.8e-113 mhqD S Carboxylesterase
JOLHEECK_01012 4.8e-108 yodC C nitroreductase
JOLHEECK_01013 1.7e-57 yodB K transcriptional
JOLHEECK_01014 3.8e-66 yodA S tautomerase
JOLHEECK_01015 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
JOLHEECK_01016 3.4e-09
JOLHEECK_01017 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
JOLHEECK_01018 6.6e-162 rarD S -transporter
JOLHEECK_01019 1.5e-43
JOLHEECK_01020 2.2e-60 yojF S Protein of unknown function (DUF1806)
JOLHEECK_01021 2.1e-125 yojG S deacetylase
JOLHEECK_01022 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JOLHEECK_01023 4.2e-245 norM V Multidrug efflux pump
JOLHEECK_01025 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JOLHEECK_01026 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
JOLHEECK_01027 4.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JOLHEECK_01028 4.8e-90 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JOLHEECK_01029 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
JOLHEECK_01030 0.0 yojO P Von Willebrand factor
JOLHEECK_01031 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
JOLHEECK_01032 3.5e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
JOLHEECK_01033 8.6e-168 yocS S -transporter
JOLHEECK_01034 9.9e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
JOLHEECK_01035 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
JOLHEECK_01036 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
JOLHEECK_01037 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
JOLHEECK_01038 2.7e-31 yozC
JOLHEECK_01039 4.2e-56 yozO S Bacterial PH domain
JOLHEECK_01040 1.9e-36 yocN
JOLHEECK_01041 1.1e-40 yozN
JOLHEECK_01042 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
JOLHEECK_01043 6.6e-34
JOLHEECK_01044 6.4e-54 yocL
JOLHEECK_01045 3.3e-83 dksA T general stress protein
JOLHEECK_01046 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JOLHEECK_01047 0.0 recQ 3.6.4.12 L DNA helicase
JOLHEECK_01048 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
JOLHEECK_01049 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOLHEECK_01050 1.7e-196 desK 2.7.13.3 T Histidine kinase
JOLHEECK_01051 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
JOLHEECK_01052 1.5e-188 yocD 3.4.17.13 V peptidase S66
JOLHEECK_01053 1.2e-93 yocC
JOLHEECK_01054 1.3e-142
JOLHEECK_01055 1.5e-92 yozB S membrane
JOLHEECK_01056 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JOLHEECK_01057 1e-51 czrA K transcriptional
JOLHEECK_01058 1.8e-90 yobW
JOLHEECK_01059 6.2e-171 yobV K WYL domain
JOLHEECK_01060 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
JOLHEECK_01061 2.8e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
JOLHEECK_01062 1.3e-97 yobS K Transcriptional regulator
JOLHEECK_01063 5.3e-141 yobR 2.3.1.1 J FR47-like protein
JOLHEECK_01064 3.8e-136 yobQ K helix_turn_helix, arabinose operon control protein
JOLHEECK_01065 1.4e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
JOLHEECK_01066 0.0 yobO M Pectate lyase superfamily protein
JOLHEECK_01067 4.4e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
JOLHEECK_01068 9.1e-101 yokH G SMI1 / KNR4 family
JOLHEECK_01069 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
JOLHEECK_01070 2.8e-84 S SMI1-KNR4 cell-wall
JOLHEECK_01072 2.9e-272 kdpA 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JOLHEECK_01073 0.0 kdpB 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JOLHEECK_01074 1.2e-63 kdpC 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JOLHEECK_01075 2.7e-176 T PhoQ Sensor
JOLHEECK_01077 1.7e-40
JOLHEECK_01079 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
JOLHEECK_01080 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
JOLHEECK_01083 3.8e-165 bla 3.5.2.6 V beta-lactamase
JOLHEECK_01084 4.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
JOLHEECK_01085 1.8e-77 yoaW
JOLHEECK_01086 1.5e-158 yijE EG EamA-like transporter family
JOLHEECK_01087 8.6e-159 yoaU K LysR substrate binding domain
JOLHEECK_01088 5.3e-147 yoaT S Protein of unknown function (DUF817)
JOLHEECK_01089 4.4e-30 yozG K Transcriptional regulator
JOLHEECK_01090 2.8e-74 yoaS S Protein of unknown function (DUF2975)
JOLHEECK_01091 9.3e-172 yoaR V vancomycin resistance protein
JOLHEECK_01092 7.3e-86
JOLHEECK_01095 7.9e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
JOLHEECK_01097 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
JOLHEECK_01098 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
JOLHEECK_01099 2.3e-111 yoaK S Membrane
JOLHEECK_01100 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
JOLHEECK_01101 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
JOLHEECK_01102 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
JOLHEECK_01103 1.5e-38 S Protein of unknown function (DUF4025)
JOLHEECK_01104 2.2e-07
JOLHEECK_01105 3.3e-90 purR K Transcriptional regulator
JOLHEECK_01106 3.2e-151 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
JOLHEECK_01107 1.6e-205 S Oxidoreductase family, C-terminal alpha/beta domain
JOLHEECK_01108 3e-172 iolT EGP Major facilitator Superfamily
JOLHEECK_01109 6.6e-32 yoaF
JOLHEECK_01110 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JOLHEECK_01111 3.8e-99 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOLHEECK_01112 1.7e-70 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOLHEECK_01113 5.3e-278 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
JOLHEECK_01114 1.2e-233 yoaB EGP Major facilitator Superfamily
JOLHEECK_01115 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
JOLHEECK_01116 1.8e-138 V AAA domain, putative AbiEii toxin, Type IV TA system
JOLHEECK_01117 2.9e-94 V ABC-2 family transporter protein
JOLHEECK_01118 3.8e-126 V ABC-2 family transporter protein
JOLHEECK_01119 5.6e-92 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JOLHEECK_01120 2.5e-130 yoxB
JOLHEECK_01121 7e-39 yoxC S Bacterial protein of unknown function (DUF948)
JOLHEECK_01122 7.7e-121 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JOLHEECK_01123 2e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
JOLHEECK_01124 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JOLHEECK_01125 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JOLHEECK_01126 3.9e-154 gltC K Transcriptional regulator
JOLHEECK_01127 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
JOLHEECK_01128 6.6e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
JOLHEECK_01129 8e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
JOLHEECK_01130 2.3e-156 gltR1 K Transcriptional regulator
JOLHEECK_01131 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
JOLHEECK_01132 3e-34 yoeD G Helix-turn-helix domain
JOLHEECK_01133 2.2e-96 L Integrase
JOLHEECK_01135 2.6e-97 yoeB S IseA DL-endopeptidase inhibitor
JOLHEECK_01136 2.3e-246 yoeA V MATE efflux family protein
JOLHEECK_01137 5.6e-191 yoxA 5.1.3.3 G Aldose 1-epimerase
JOLHEECK_01138 1.4e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
JOLHEECK_01139 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOLHEECK_01140 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOLHEECK_01141 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOLHEECK_01142 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOLHEECK_01143 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
JOLHEECK_01144 4e-63 yngL S Protein of unknown function (DUF1360)
JOLHEECK_01145 5e-303 yngK T Glycosyl hydrolase-like 10
JOLHEECK_01146 1.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
JOLHEECK_01147 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JOLHEECK_01148 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
JOLHEECK_01149 2.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
JOLHEECK_01150 2.9e-165 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
JOLHEECK_01151 6.4e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
JOLHEECK_01152 1.5e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
JOLHEECK_01153 2.6e-230 nrnB S phosphohydrolase (DHH superfamily)
JOLHEECK_01154 5.5e-104 yngC S membrane-associated protein
JOLHEECK_01155 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JOLHEECK_01156 1.6e-79 yngA S membrane
JOLHEECK_01157 2.4e-297 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
JOLHEECK_01158 1.2e-249 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
JOLHEECK_01160 1.7e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
JOLHEECK_01161 1.8e-251 agcS E Sodium alanine symporter
JOLHEECK_01162 1.3e-57 ynfC
JOLHEECK_01163 2.3e-12
JOLHEECK_01164 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JOLHEECK_01165 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JOLHEECK_01166 8.6e-69 yccU S CoA-binding protein
JOLHEECK_01167 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JOLHEECK_01168 4.1e-49 yneR S Belongs to the HesB IscA family
JOLHEECK_01169 1.7e-53 yneQ
JOLHEECK_01170 2e-73 yneP S Thioesterase-like superfamily
JOLHEECK_01171 3.9e-35 tlp S Belongs to the Tlp family
JOLHEECK_01172 3.1e-08 sspN S Small acid-soluble spore protein N family
JOLHEECK_01174 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JOLHEECK_01175 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JOLHEECK_01176 2.2e-14 sspO S Belongs to the SspO family
JOLHEECK_01177 3.9e-19 sspP S Belongs to the SspP family
JOLHEECK_01178 1.2e-64 hspX O Spore coat protein
JOLHEECK_01179 4.2e-74 yneK S Protein of unknown function (DUF2621)
JOLHEECK_01180 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
JOLHEECK_01181 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
JOLHEECK_01182 7.1e-127 ccdA O cytochrome c biogenesis protein
JOLHEECK_01183 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
JOLHEECK_01184 1.8e-28 yneF S UPF0154 protein
JOLHEECK_01185 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
JOLHEECK_01186 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JOLHEECK_01187 1.3e-32 ynzC S UPF0291 protein
JOLHEECK_01188 5e-111 yneB L resolvase
JOLHEECK_01189 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
JOLHEECK_01190 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JOLHEECK_01191 1.3e-75 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
JOLHEECK_01192 5.8e-74 yndM S Protein of unknown function (DUF2512)
JOLHEECK_01193 8.6e-139 yndL S Replication protein
JOLHEECK_01195 0.0 yndJ S YndJ-like protein
JOLHEECK_01196 2.6e-117 yndH S Domain of unknown function (DUF4166)
JOLHEECK_01197 7.7e-154 yndG S DoxX-like family
JOLHEECK_01198 3.4e-88 gerLC S Spore germination protein
JOLHEECK_01199 1.8e-146 gerAA EG Spore germination protein
JOLHEECK_01200 2.8e-52 gerAA EG Spore germination protein
JOLHEECK_01203 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
JOLHEECK_01204 1.8e-71
JOLHEECK_01205 7.9e-25 tatA U protein secretion
JOLHEECK_01208 1.1e-69 S Domain of unknown function, YrpD
JOLHEECK_01209 1.7e-48 S Domain of unknown function, YrpD
JOLHEECK_01211 2.1e-162 S Thymidylate synthase
JOLHEECK_01214 5.2e-15
JOLHEECK_01215 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
JOLHEECK_01217 4.5e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JOLHEECK_01218 1.4e-254 iolT EGP Major facilitator Superfamily
JOLHEECK_01219 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
JOLHEECK_01220 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
JOLHEECK_01221 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
JOLHEECK_01222 6.8e-212 xylR GK ROK family
JOLHEECK_01223 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
JOLHEECK_01224 7.9e-255 xynT G MFS/sugar transport protein
JOLHEECK_01225 8.7e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
JOLHEECK_01227 8.6e-15 ynaF
JOLHEECK_01228 2.1e-117 ynaE S Domain of unknown function (DUF3885)
JOLHEECK_01229 5.5e-20 K Cro/C1-type HTH DNA-binding domain
JOLHEECK_01230 4.7e-08 S Uncharacterised protein family (UPF0715)
JOLHEECK_01231 4.1e-73 S CAAX protease self-immunity
JOLHEECK_01232 2e-97 ynaD J Acetyltransferase (GNAT) domain
JOLHEECK_01233 4.1e-11 S Protein of unknown function (DUF1433)
JOLHEECK_01234 3.1e-113 ynaC
JOLHEECK_01235 8.9e-90 G SMI1-KNR4 cell-wall
JOLHEECK_01236 2.1e-16
JOLHEECK_01237 1.6e-31
JOLHEECK_01238 1.1e-09
JOLHEECK_01239 7e-261 glnA 6.3.1.2 E glutamine synthetase
JOLHEECK_01240 1.1e-68 glnR K transcriptional
JOLHEECK_01241 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
JOLHEECK_01242 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JOLHEECK_01243 1.7e-176 spoVK O stage V sporulation protein K
JOLHEECK_01244 2.6e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOLHEECK_01245 2e-109 ymaB
JOLHEECK_01246 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOLHEECK_01247 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOLHEECK_01248 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
JOLHEECK_01249 4.5e-22 ymzA
JOLHEECK_01250 8.2e-23
JOLHEECK_01251 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
JOLHEECK_01252 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JOLHEECK_01253 2.1e-46 ymaF S YmaF family
JOLHEECK_01255 5.4e-50 ebrA P Small Multidrug Resistance protein
JOLHEECK_01256 8.9e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
JOLHEECK_01257 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
JOLHEECK_01258 2.1e-126 ymaC S Replication protein
JOLHEECK_01259 1.9e-07 K Transcriptional regulator
JOLHEECK_01260 8.6e-251 aprX O Belongs to the peptidase S8 family
JOLHEECK_01261 8.1e-162 ymaE S Metallo-beta-lactamase superfamily
JOLHEECK_01262 2e-61 ymzB
JOLHEECK_01263 6.3e-232 cypA C Cytochrome P450
JOLHEECK_01264 0.0 pks13 HQ Beta-ketoacyl synthase
JOLHEECK_01265 0.0 dhbF IQ polyketide synthase
JOLHEECK_01266 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
JOLHEECK_01267 0.0 pfaA Q Polyketide synthase of type I
JOLHEECK_01268 0.0 rhiB IQ polyketide synthase
JOLHEECK_01269 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
JOLHEECK_01270 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
JOLHEECK_01271 1.3e-245 pksG 2.3.3.10 I synthase
JOLHEECK_01272 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JOLHEECK_01273 1.4e-37 acpK IQ Phosphopantetheine attachment site
JOLHEECK_01274 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JOLHEECK_01275 2.4e-186 pksD Q Acyl transferase domain
JOLHEECK_01277 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JOLHEECK_01278 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
JOLHEECK_01279 4.4e-109 pksA K Transcriptional regulator
JOLHEECK_01280 1.2e-97 ymcC S Membrane
JOLHEECK_01282 2.5e-69 S Regulatory protein YrvL
JOLHEECK_01283 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JOLHEECK_01284 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JOLHEECK_01285 2.2e-88 cotE S Spore coat protein
JOLHEECK_01286 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
JOLHEECK_01287 1.9e-294 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JOLHEECK_01288 3e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
JOLHEECK_01289 1.9e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
JOLHEECK_01290 1.2e-36 spoVS S Stage V sporulation protein S
JOLHEECK_01291 1.9e-152 ymdB S protein conserved in bacteria
JOLHEECK_01292 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
JOLHEECK_01293 1e-215 pbpX V Beta-lactamase
JOLHEECK_01294 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JOLHEECK_01295 1.3e-235 cinA 3.5.1.42 S Belongs to the CinA family
JOLHEECK_01296 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JOLHEECK_01297 7.3e-116 ymfM S protein conserved in bacteria
JOLHEECK_01298 2.7e-143 ymfK S Protein of unknown function (DUF3388)
JOLHEECK_01299 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
JOLHEECK_01300 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
JOLHEECK_01301 1.4e-242 ymfH S zinc protease
JOLHEECK_01302 2e-233 ymfF S Peptidase M16
JOLHEECK_01303 3.8e-205 ymfD EGP Major facilitator Superfamily
JOLHEECK_01304 1.4e-133 ymfC K Transcriptional regulator
JOLHEECK_01305 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JOLHEECK_01306 4.4e-32 S YlzJ-like protein
JOLHEECK_01307 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
JOLHEECK_01308 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JOLHEECK_01309 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JOLHEECK_01310 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
JOLHEECK_01311 1.2e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JOLHEECK_01312 6.3e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
JOLHEECK_01313 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
JOLHEECK_01314 2.6e-42 ymxH S YlmC YmxH family
JOLHEECK_01315 4.4e-233 pepR S Belongs to the peptidase M16 family
JOLHEECK_01316 6.1e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
JOLHEECK_01317 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
JOLHEECK_01318 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JOLHEECK_01319 1.1e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JOLHEECK_01320 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JOLHEECK_01321 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JOLHEECK_01322 3e-44 ylxP S protein conserved in bacteria
JOLHEECK_01323 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JOLHEECK_01324 3.1e-47 ylxQ J ribosomal protein
JOLHEECK_01325 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
JOLHEECK_01326 1.1e-203 nusA K Participates in both transcription termination and antitermination
JOLHEECK_01327 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
JOLHEECK_01328 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JOLHEECK_01329 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JOLHEECK_01330 7.7e-233 rasP M zinc metalloprotease
JOLHEECK_01331 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
JOLHEECK_01332 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
JOLHEECK_01333 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JOLHEECK_01334 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JOLHEECK_01335 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JOLHEECK_01336 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JOLHEECK_01337 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
JOLHEECK_01338 3.1e-76 ylxL
JOLHEECK_01339 9.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOLHEECK_01340 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
JOLHEECK_01341 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
JOLHEECK_01342 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
JOLHEECK_01343 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
JOLHEECK_01344 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
JOLHEECK_01345 4.1e-156 flhG D Belongs to the ParA family
JOLHEECK_01346 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
JOLHEECK_01347 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JOLHEECK_01348 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JOLHEECK_01349 3.6e-132 fliR N Flagellar biosynthetic protein FliR
JOLHEECK_01350 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
JOLHEECK_01351 2.7e-96 fliZ N Flagellar biosynthesis protein, FliO
JOLHEECK_01352 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
JOLHEECK_01353 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JOLHEECK_01354 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
JOLHEECK_01355 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
JOLHEECK_01356 8.2e-140 flgG N Flagellar basal body rod
JOLHEECK_01357 2.3e-72 flgD N Flagellar basal body rod modification protein
JOLHEECK_01358 5.1e-220 fliK N Flagellar hook-length control protein
JOLHEECK_01359 2.2e-36 ylxF S MgtE intracellular N domain
JOLHEECK_01360 1.5e-69 fliJ N Flagellar biosynthesis chaperone
JOLHEECK_01361 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
JOLHEECK_01362 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
JOLHEECK_01363 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
JOLHEECK_01364 1.6e-254 fliF N The M ring may be actively involved in energy transduction
JOLHEECK_01365 1.9e-31 fliE N Flagellar hook-basal body
JOLHEECK_01366 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
JOLHEECK_01367 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
JOLHEECK_01368 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JOLHEECK_01369 4.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JOLHEECK_01370 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JOLHEECK_01371 2.5e-169 xerC L tyrosine recombinase XerC
JOLHEECK_01372 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JOLHEECK_01373 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JOLHEECK_01374 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
JOLHEECK_01375 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JOLHEECK_01376 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
JOLHEECK_01377 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
JOLHEECK_01378 4.3e-287 ylqG
JOLHEECK_01379 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JOLHEECK_01380 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JOLHEECK_01381 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JOLHEECK_01382 7.8e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JOLHEECK_01383 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JOLHEECK_01384 6.3e-61 ylqD S YlqD protein
JOLHEECK_01385 4.5e-36 ylqC S Belongs to the UPF0109 family
JOLHEECK_01386 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JOLHEECK_01387 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JOLHEECK_01388 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JOLHEECK_01389 3.5e-85
JOLHEECK_01390 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JOLHEECK_01391 0.0 smc D Required for chromosome condensation and partitioning
JOLHEECK_01392 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JOLHEECK_01393 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JOLHEECK_01394 1.1e-127 IQ reductase
JOLHEECK_01395 2.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JOLHEECK_01396 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JOLHEECK_01397 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
JOLHEECK_01398 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JOLHEECK_01399 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
JOLHEECK_01400 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
JOLHEECK_01401 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
JOLHEECK_01402 5.5e-59 asp S protein conserved in bacteria
JOLHEECK_01403 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JOLHEECK_01404 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
JOLHEECK_01405 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JOLHEECK_01406 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JOLHEECK_01407 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
JOLHEECK_01408 1.6e-140 stp 3.1.3.16 T phosphatase
JOLHEECK_01409 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
JOLHEECK_01410 5.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JOLHEECK_01411 5.2e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JOLHEECK_01412 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JOLHEECK_01413 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JOLHEECK_01414 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JOLHEECK_01415 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
JOLHEECK_01416 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JOLHEECK_01417 1.5e-40 ylzA S Belongs to the UPF0296 family
JOLHEECK_01418 3.1e-156 yloC S stress-induced protein
JOLHEECK_01419 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
JOLHEECK_01420 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
JOLHEECK_01421 6.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
JOLHEECK_01422 2.2e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
JOLHEECK_01423 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
JOLHEECK_01424 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
JOLHEECK_01425 1.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
JOLHEECK_01426 1.2e-178 cysP P phosphate transporter
JOLHEECK_01427 1.7e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
JOLHEECK_01429 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JOLHEECK_01430 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JOLHEECK_01431 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JOLHEECK_01432 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
JOLHEECK_01433 0.0 carB 6.3.5.5 F Belongs to the CarB family
JOLHEECK_01434 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JOLHEECK_01435 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JOLHEECK_01436 8.5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JOLHEECK_01437 2.6e-231 pyrP F Xanthine uracil
JOLHEECK_01438 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JOLHEECK_01439 3.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JOLHEECK_01440 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JOLHEECK_01441 1.3e-63 dksA T COG1734 DnaK suppressor protein
JOLHEECK_01442 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JOLHEECK_01443 2.6e-67 divIVA D Cell division initiation protein
JOLHEECK_01444 8.2e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
JOLHEECK_01445 1.6e-39 yggT S membrane
JOLHEECK_01446 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
JOLHEECK_01447 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JOLHEECK_01448 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
JOLHEECK_01449 2.4e-37 ylmC S sporulation protein
JOLHEECK_01450 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
JOLHEECK_01451 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
JOLHEECK_01452 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOLHEECK_01453 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOLHEECK_01454 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
JOLHEECK_01455 0.0 bpr O COG1404 Subtilisin-like serine proteases
JOLHEECK_01456 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JOLHEECK_01457 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JOLHEECK_01458 2.8e-55 sbp S small basic protein
JOLHEECK_01459 2.6e-90 ylxX S protein conserved in bacteria
JOLHEECK_01460 4.1e-103 ylxW S protein conserved in bacteria
JOLHEECK_01461 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JOLHEECK_01462 5.3e-167 murB 1.3.1.98 M cell wall formation
JOLHEECK_01463 6.7e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JOLHEECK_01464 5.7e-186 spoVE D Belongs to the SEDS family
JOLHEECK_01465 1.9e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JOLHEECK_01466 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JOLHEECK_01467 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JOLHEECK_01468 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
JOLHEECK_01469 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
JOLHEECK_01470 3.7e-44 ftsL D Essential cell division protein
JOLHEECK_01471 4.7e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JOLHEECK_01472 2.9e-78 mraZ K Belongs to the MraZ family
JOLHEECK_01473 3.2e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JOLHEECK_01474 6.1e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JOLHEECK_01475 1.5e-88 ylbP K n-acetyltransferase
JOLHEECK_01476 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
JOLHEECK_01477 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JOLHEECK_01478 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
JOLHEECK_01480 4e-234 ylbM S Belongs to the UPF0348 family
JOLHEECK_01481 6.8e-187 ylbL T Belongs to the peptidase S16 family
JOLHEECK_01482 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
JOLHEECK_01483 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
JOLHEECK_01484 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JOLHEECK_01485 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
JOLHEECK_01486 3.7e-38 ylbG S UPF0298 protein
JOLHEECK_01487 1.8e-75 ylbF S Belongs to the UPF0342 family
JOLHEECK_01488 2.5e-36 ylbE S YlbE-like protein
JOLHEECK_01489 4.1e-63 ylbD S Putative coat protein
JOLHEECK_01490 9.6e-200 ylbC S protein with SCP PR1 domains
JOLHEECK_01491 2.6e-74 ylbB T COG0517 FOG CBS domain
JOLHEECK_01492 7e-62 ylbA S YugN-like family
JOLHEECK_01493 3.4e-166 ctaG S cytochrome c oxidase
JOLHEECK_01494 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
JOLHEECK_01495 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
JOLHEECK_01496 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JOLHEECK_01497 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
JOLHEECK_01498 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
JOLHEECK_01499 7.7e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
JOLHEECK_01500 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JOLHEECK_01501 4.5e-214 ftsW D Belongs to the SEDS family
JOLHEECK_01502 8.7e-44 ylaN S Belongs to the UPF0358 family
JOLHEECK_01503 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
JOLHEECK_01504 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JOLHEECK_01505 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
JOLHEECK_01506 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JOLHEECK_01507 2.5e-32 ylaI S protein conserved in bacteria
JOLHEECK_01508 4.2e-47 ylaH S YlaH-like protein
JOLHEECK_01509 0.0 typA T GTP-binding protein TypA
JOLHEECK_01510 8.2e-22 S Family of unknown function (DUF5325)
JOLHEECK_01511 4.1e-38 ylaE
JOLHEECK_01512 7.1e-12 sigC S Putative zinc-finger
JOLHEECK_01513 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
JOLHEECK_01514 2.7e-42 ylaB
JOLHEECK_01515 0.0 ylaA
JOLHEECK_01516 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
JOLHEECK_01517 8.7e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JOLHEECK_01518 2.2e-76 ykzC S Acetyltransferase (GNAT) family
JOLHEECK_01519 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
JOLHEECK_01520 7.1e-26 ykzI
JOLHEECK_01521 4.6e-117 yktB S Belongs to the UPF0637 family
JOLHEECK_01522 1.6e-42 yktA S Belongs to the UPF0223 family
JOLHEECK_01523 3.5e-277 speA 4.1.1.19 E Arginine
JOLHEECK_01524 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
JOLHEECK_01525 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JOLHEECK_01526 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JOLHEECK_01527 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JOLHEECK_01528 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JOLHEECK_01529 2e-115 recN L Putative cell-wall binding lipoprotein
JOLHEECK_01531 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JOLHEECK_01532 1.4e-147 ykrA S hydrolases of the HAD superfamily
JOLHEECK_01533 8.2e-31 ykzG S Belongs to the UPF0356 family
JOLHEECK_01534 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JOLHEECK_01535 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JOLHEECK_01536 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
JOLHEECK_01537 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
JOLHEECK_01538 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
JOLHEECK_01539 1.5e-43 abrB K of stationary sporulation gene expression
JOLHEECK_01540 7.7e-183 mreB D Rod-share determining protein MreBH
JOLHEECK_01541 1.1e-12 S Uncharacterized protein YkpC
JOLHEECK_01542 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
JOLHEECK_01543 1.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JOLHEECK_01544 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JOLHEECK_01545 8.1e-39 ykoA
JOLHEECK_01546 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JOLHEECK_01547 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
JOLHEECK_01548 3.1e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
JOLHEECK_01549 3.1e-136 fruR K Transcriptional regulator
JOLHEECK_01550 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
JOLHEECK_01551 2.5e-124 macB V ABC transporter, ATP-binding protein
JOLHEECK_01552 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JOLHEECK_01553 1e-117 yknW S Yip1 domain
JOLHEECK_01554 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
JOLHEECK_01555 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
JOLHEECK_01556 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JOLHEECK_01557 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
JOLHEECK_01558 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
JOLHEECK_01559 8.1e-246 moeA 2.10.1.1 H molybdopterin
JOLHEECK_01560 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JOLHEECK_01561 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
JOLHEECK_01562 4.2e-146 yknT
JOLHEECK_01563 5.8e-95 rok K Repressor of ComK
JOLHEECK_01564 7e-80 ykuV CO thiol-disulfide
JOLHEECK_01565 3.9e-101 ykuU O Alkyl hydroperoxide reductase
JOLHEECK_01566 8.8e-142 ykuT M Mechanosensitive ion channel
JOLHEECK_01567 9e-37 ykuS S Belongs to the UPF0180 family
JOLHEECK_01568 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JOLHEECK_01569 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JOLHEECK_01570 3.9e-78 fld C Flavodoxin
JOLHEECK_01571 3e-175 ykuO
JOLHEECK_01572 8.5e-84 fld C Flavodoxin domain
JOLHEECK_01573 3.5e-168 ccpC K Transcriptional regulator
JOLHEECK_01574 1.6e-76 ykuL S CBS domain
JOLHEECK_01575 3.9e-27 ykzF S Antirepressor AbbA
JOLHEECK_01576 4.4e-94 ykuK S Ribonuclease H-like
JOLHEECK_01577 3.9e-37 ykuJ S protein conserved in bacteria
JOLHEECK_01578 5.2e-234 ykuI T Diguanylate phosphodiesterase
JOLHEECK_01579 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOLHEECK_01580 1.6e-165 ykuE S Metallophosphoesterase
JOLHEECK_01581 1.5e-86 ykuD S protein conserved in bacteria
JOLHEECK_01582 1.7e-235 ykuC EGP Major facilitator Superfamily
JOLHEECK_01583 1.7e-84 ykyB S YkyB-like protein
JOLHEECK_01584 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
JOLHEECK_01585 2.2e-15
JOLHEECK_01586 8e-224 patA 2.6.1.1 E Aminotransferase
JOLHEECK_01587 0.0 pilS 2.7.13.3 T Histidine kinase
JOLHEECK_01588 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
JOLHEECK_01589 8e-124 ykwD J protein with SCP PR1 domains
JOLHEECK_01590 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
JOLHEECK_01591 1.6e-261 mcpC NT chemotaxis protein
JOLHEECK_01592 4.9e-128 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOLHEECK_01593 7.5e-202 splB 4.1.99.14 L Spore photoproduct lyase
JOLHEECK_01594 7.2e-39 splA S Transcriptional regulator
JOLHEECK_01595 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JOLHEECK_01596 2.1e-39 ptsH G phosphocarrier protein HPr
JOLHEECK_01597 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOLHEECK_01598 2.2e-127 glcT K antiterminator
JOLHEECK_01600 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
JOLHEECK_01601 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
JOLHEECK_01602 2.3e-09
JOLHEECK_01603 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
JOLHEECK_01604 1.6e-88 stoA CO thiol-disulfide
JOLHEECK_01605 3.8e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOLHEECK_01606 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
JOLHEECK_01607 2.8e-28
JOLHEECK_01608 6e-25 ykvS S protein conserved in bacteria
JOLHEECK_01609 5.6e-46 ykvR S Protein of unknown function (DUF3219)
JOLHEECK_01610 1.4e-162 G Glycosyl hydrolases family 18
JOLHEECK_01611 3.5e-35 3.5.1.104 M LysM domain
JOLHEECK_01612 9.9e-216 ykvP 3.5.1.28 M Glycosyl transferases group 1
JOLHEECK_01613 2.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
JOLHEECK_01614 2e-61 ykvN K Transcriptional regulator
JOLHEECK_01615 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JOLHEECK_01616 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
JOLHEECK_01617 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
JOLHEECK_01618 9.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JOLHEECK_01619 2.6e-178 ykvI S membrane
JOLHEECK_01620 0.0 clpE O Belongs to the ClpA ClpB family
JOLHEECK_01621 1e-137 motA N flagellar motor
JOLHEECK_01622 2.5e-125 motB N Flagellar motor protein
JOLHEECK_01623 1.3e-75 ykvE K transcriptional
JOLHEECK_01624 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
JOLHEECK_01625 1.8e-64 eag
JOLHEECK_01626 6.4e-09 S Spo0E like sporulation regulatory protein
JOLHEECK_01627 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
JOLHEECK_01628 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JOLHEECK_01629 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
JOLHEECK_01630 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JOLHEECK_01631 1.4e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
JOLHEECK_01632 1.5e-230 mtnE 2.6.1.83 E Aminotransferase
JOLHEECK_01633 1e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JOLHEECK_01634 2.4e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JOLHEECK_01635 1.4e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JOLHEECK_01637 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JOLHEECK_01638 0.0 kinE 2.7.13.3 T Histidine kinase
JOLHEECK_01639 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
JOLHEECK_01640 4.1e-18 ykzE
JOLHEECK_01641 1.2e-10 ydfR S Protein of unknown function (DUF421)
JOLHEECK_01642 1.1e-232 ktrB P COG0168 Trk-type K transport systems, membrane components
JOLHEECK_01643 3.5e-155 htpX O Belongs to the peptidase M48B family
JOLHEECK_01644 1.5e-124 ykrK S Domain of unknown function (DUF1836)
JOLHEECK_01645 1.9e-26 sspD S small acid-soluble spore protein
JOLHEECK_01646 9.1e-116 rsgI S Anti-sigma factor N-terminus
JOLHEECK_01647 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOLHEECK_01648 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
JOLHEECK_01649 3.5e-109 ykoX S membrane-associated protein
JOLHEECK_01650 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
JOLHEECK_01651 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JOLHEECK_01652 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
JOLHEECK_01653 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JOLHEECK_01654 0.0 ykoS
JOLHEECK_01655 3.5e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
JOLHEECK_01656 1.4e-98 ykoP G polysaccharide deacetylase
JOLHEECK_01657 3.1e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
JOLHEECK_01658 1.3e-81 mhqR K transcriptional
JOLHEECK_01659 6.9e-26 ykoL
JOLHEECK_01660 5.9e-18
JOLHEECK_01661 1.4e-53 tnrA K transcriptional
JOLHEECK_01662 2.2e-222 mgtE P Acts as a magnesium transporter
JOLHEECK_01665 8.3e-85 ykoJ S Peptidase propeptide and YPEB domain
JOLHEECK_01666 9.9e-110 ykoI S Peptidase propeptide and YPEB domain
JOLHEECK_01667 1.4e-240 ykoH 2.7.13.3 T Histidine kinase
JOLHEECK_01668 7.9e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOLHEECK_01669 1.6e-108 ykoF S YKOF-related Family
JOLHEECK_01670 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
JOLHEECK_01671 2.2e-304 P ABC transporter, ATP-binding protein
JOLHEECK_01672 5.3e-136 ykoC P Cobalt transport protein
JOLHEECK_01673 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JOLHEECK_01674 1.6e-174 isp O Belongs to the peptidase S8 family
JOLHEECK_01675 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JOLHEECK_01676 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
JOLHEECK_01678 2.4e-71 ohrB O Organic hydroperoxide resistance protein
JOLHEECK_01679 4.8e-73 ohrR K COG1846 Transcriptional regulators
JOLHEECK_01680 1.3e-70 ohrA O Organic hydroperoxide resistance protein
JOLHEECK_01681 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JOLHEECK_01682 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JOLHEECK_01683 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
JOLHEECK_01684 7e-50 ykkD P Multidrug resistance protein
JOLHEECK_01685 3.5e-55 ykkC P Multidrug resistance protein
JOLHEECK_01686 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JOLHEECK_01687 4.8e-96 ykkA S Protein of unknown function (DUF664)
JOLHEECK_01688 7.8e-129 ykjA S Protein of unknown function (DUF421)
JOLHEECK_01689 5.5e-09
JOLHEECK_01690 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JOLHEECK_01691 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
JOLHEECK_01692 2e-160 ykgA E Amidinotransferase
JOLHEECK_01693 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
JOLHEECK_01694 9.4e-186 ykfD E Belongs to the ABC transporter superfamily
JOLHEECK_01695 2.7e-163 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
JOLHEECK_01696 2.3e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
JOLHEECK_01697 1.3e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
JOLHEECK_01699 0.0 dppE E ABC transporter substrate-binding protein
JOLHEECK_01700 1.3e-187 dppD P Belongs to the ABC transporter superfamily
JOLHEECK_01701 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOLHEECK_01702 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOLHEECK_01703 2.5e-152 dppA E D-aminopeptidase
JOLHEECK_01704 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
JOLHEECK_01705 7.5e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOLHEECK_01707 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JOLHEECK_01708 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JOLHEECK_01709 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
JOLHEECK_01710 4e-240 steT E amino acid
JOLHEECK_01711 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
JOLHEECK_01712 5.8e-175 pit P phosphate transporter
JOLHEECK_01713 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
JOLHEECK_01714 6.7e-23 spoIISB S Stage II sporulation protein SB
JOLHEECK_01715 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOLHEECK_01716 9.3e-40 xhlB S SPP1 phage holin
JOLHEECK_01717 6.2e-39 xhlA S Haemolysin XhlA
JOLHEECK_01718 1.7e-151 xepA
JOLHEECK_01719 5.5e-22 xkdX
JOLHEECK_01720 5.4e-53 xkdW S XkdW protein
JOLHEECK_01721 1e-261
JOLHEECK_01722 1.5e-40
JOLHEECK_01723 1.2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
JOLHEECK_01724 6.7e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
JOLHEECK_01725 3.1e-69 xkdS S Protein of unknown function (DUF2634)
JOLHEECK_01726 2.1e-39 xkdR S Protein of unknown function (DUF2577)
JOLHEECK_01727 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
JOLHEECK_01728 4.1e-121 xkdP S Lysin motif
JOLHEECK_01729 0.0 xkdO L Transglycosylase SLT domain
JOLHEECK_01730 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
JOLHEECK_01731 6.1e-76 xkdM S Phage tail tube protein
JOLHEECK_01732 2.5e-256 xkdK S Phage tail sheath C-terminal domain
JOLHEECK_01733 1.9e-77 xkdJ
JOLHEECK_01734 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
JOLHEECK_01735 8.7e-65 yqbH S Domain of unknown function (DUF3599)
JOLHEECK_01736 5.5e-65 yqbG S Protein of unknown function (DUF3199)
JOLHEECK_01737 1.3e-168 xkdG S Phage capsid family
JOLHEECK_01738 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
JOLHEECK_01739 6e-285 yqbA S portal protein
JOLHEECK_01740 1.4e-253 xtmB S phage terminase, large subunit
JOLHEECK_01741 5.3e-139 xtmA L phage terminase small subunit
JOLHEECK_01742 2.2e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
JOLHEECK_01743 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
JOLHEECK_01746 9.2e-118 xkdC L Bacterial dnaA protein
JOLHEECK_01747 5e-156 xkdB K sequence-specific DNA binding
JOLHEECK_01749 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
JOLHEECK_01750 4.3e-109 xkdA E IrrE N-terminal-like domain
JOLHEECK_01751 9.8e-160 ydbD P Catalase
JOLHEECK_01752 2.1e-111 yjqB S Pfam:DUF867
JOLHEECK_01753 1.8e-60 yjqA S Bacterial PH domain
JOLHEECK_01754 6.8e-165 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
JOLHEECK_01755 5.2e-37 S YCII-related domain
JOLHEECK_01757 1e-212 S response regulator aspartate phosphatase
JOLHEECK_01758 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
JOLHEECK_01759 2.3e-78 yjoA S DinB family
JOLHEECK_01760 7.4e-130 MA20_18170 S membrane transporter protein
JOLHEECK_01761 4.6e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
JOLHEECK_01762 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
JOLHEECK_01763 2.3e-184 exuR K transcriptional
JOLHEECK_01764 3.7e-227 exuT G Sugar (and other) transporter
JOLHEECK_01765 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOLHEECK_01766 2.3e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
JOLHEECK_01767 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
JOLHEECK_01768 4.3e-194 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
JOLHEECK_01769 5.8e-250 yjmB G symporter YjmB
JOLHEECK_01770 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
JOLHEECK_01771 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
JOLHEECK_01772 7.1e-66 yjlC S Protein of unknown function (DUF1641)
JOLHEECK_01773 2.8e-93 yjlB S Cupin domain
JOLHEECK_01774 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
JOLHEECK_01775 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
JOLHEECK_01776 1.9e-122 ybbM S transport system, permease component
JOLHEECK_01777 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
JOLHEECK_01778 8.2e-30
JOLHEECK_01779 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
JOLHEECK_01780 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
JOLHEECK_01782 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
JOLHEECK_01783 8.7e-07 S Domain of unknown function (DUF4352)
JOLHEECK_01784 4.3e-95 yjgD S Protein of unknown function (DUF1641)
JOLHEECK_01785 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
JOLHEECK_01786 8.9e-104 yjgB S Domain of unknown function (DUF4309)
JOLHEECK_01787 1.2e-45 T PhoQ Sensor
JOLHEECK_01788 5.6e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
JOLHEECK_01789 8.9e-20 yjfB S Putative motility protein
JOLHEECK_01790 1.4e-81 S Protein of unknown function (DUF2690)
JOLHEECK_01791 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
JOLHEECK_01793 1.4e-173 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
JOLHEECK_01794 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
JOLHEECK_01795 4.2e-29 S Domain of unknown function (DUF4177)
JOLHEECK_01796 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JOLHEECK_01798 4.5e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
JOLHEECK_01799 4.5e-49 yjdF S Protein of unknown function (DUF2992)
JOLHEECK_01800 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
JOLHEECK_01801 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
JOLHEECK_01802 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
JOLHEECK_01804 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
JOLHEECK_01805 2.4e-33 yjcS S Antibiotic biosynthesis monooxygenase
JOLHEECK_01806 1.1e-92 yqaS L DNA packaging
JOLHEECK_01807 4.1e-49 S YjcQ protein
JOLHEECK_01808 5.3e-71 yjcP
JOLHEECK_01809 8.5e-81 L Transposase
JOLHEECK_01812 2.6e-44 yjcN
JOLHEECK_01813 7.8e-190 S Putative amidase domain
JOLHEECK_01816 5.4e-212 yjcL S Protein of unknown function (DUF819)
JOLHEECK_01817 7.7e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
JOLHEECK_01818 4.2e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JOLHEECK_01819 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JOLHEECK_01820 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
JOLHEECK_01821 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
JOLHEECK_01822 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOLHEECK_01823 1.7e-38
JOLHEECK_01824 0.0 yjcD 3.6.4.12 L DNA helicase
JOLHEECK_01825 2.9e-38 spoVIF S Stage VI sporulation protein F
JOLHEECK_01828 4.3e-56 yjcA S Protein of unknown function (DUF1360)
JOLHEECK_01829 1.1e-54 cotV S Spore Coat Protein X and V domain
JOLHEECK_01830 8.8e-24 cotW
JOLHEECK_01831 1.6e-72 cotX S Spore Coat Protein X and V domain
JOLHEECK_01832 7.6e-96 cotY S Spore coat protein Z
JOLHEECK_01833 4.4e-82 cotZ S Spore coat protein
JOLHEECK_01834 5.9e-54 yjbX S Spore coat protein
JOLHEECK_01835 9.5e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
JOLHEECK_01836 2.2e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JOLHEECK_01837 5.1e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JOLHEECK_01838 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
JOLHEECK_01839 2.6e-29 thiS H thiamine diphosphate biosynthetic process
JOLHEECK_01840 1.2e-213 thiO 1.4.3.19 E Glycine oxidase
JOLHEECK_01841 9.3e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
JOLHEECK_01842 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JOLHEECK_01843 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
JOLHEECK_01844 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
JOLHEECK_01845 2.3e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JOLHEECK_01846 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JOLHEECK_01847 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
JOLHEECK_01848 1.6e-61 yjbL S Belongs to the UPF0738 family
JOLHEECK_01849 1e-99 yjbK S protein conserved in bacteria
JOLHEECK_01850 3.8e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JOLHEECK_01851 1.1e-71 yjbI S Bacterial-like globin
JOLHEECK_01852 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
JOLHEECK_01854 1.8e-20
JOLHEECK_01855 0.0 pepF E oligoendopeptidase F
JOLHEECK_01856 2.1e-221 yjbF S Competence protein
JOLHEECK_01857 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
JOLHEECK_01858 6e-112 yjbE P Integral membrane protein TerC family
JOLHEECK_01859 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JOLHEECK_01860 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOLHEECK_01861 1.2e-203 yjbB EGP Major Facilitator Superfamily
JOLHEECK_01862 5.5e-172 oppF E Belongs to the ABC transporter superfamily
JOLHEECK_01863 1.5e-197 oppD P Belongs to the ABC transporter superfamily
JOLHEECK_01864 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOLHEECK_01865 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOLHEECK_01866 0.0 oppA E ABC transporter substrate-binding protein
JOLHEECK_01867 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
JOLHEECK_01868 6.5e-147 yjbA S Belongs to the UPF0736 family
JOLHEECK_01869 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOLHEECK_01870 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOLHEECK_01871 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
JOLHEECK_01872 6.5e-187 appF E Belongs to the ABC transporter superfamily
JOLHEECK_01873 1.8e-184 appD P Belongs to the ABC transporter superfamily
JOLHEECK_01874 7.8e-151 yjaZ O Zn-dependent protease
JOLHEECK_01875 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JOLHEECK_01876 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOLHEECK_01877 2.7e-22 yjzB
JOLHEECK_01878 4.7e-25 comZ S ComZ
JOLHEECK_01879 1.1e-183 med S Transcriptional activator protein med
JOLHEECK_01880 1.8e-101 yjaV
JOLHEECK_01881 6.8e-141 yjaU I carboxylic ester hydrolase activity
JOLHEECK_01882 2.3e-16 yjzD S Protein of unknown function (DUF2929)
JOLHEECK_01883 9.5e-28 yjzC S YjzC-like protein
JOLHEECK_01884 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JOLHEECK_01885 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
JOLHEECK_01886 9.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JOLHEECK_01887 6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
JOLHEECK_01888 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
JOLHEECK_01889 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JOLHEECK_01890 1.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JOLHEECK_01891 1.7e-88 norB G Major Facilitator Superfamily
JOLHEECK_01892 6e-266 yitY C D-arabinono-1,4-lactone oxidase
JOLHEECK_01893 1.5e-22 pilT S Proteolipid membrane potential modulator
JOLHEECK_01894 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
JOLHEECK_01895 1e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
JOLHEECK_01896 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
JOLHEECK_01897 1.2e-17 S Protein of unknown function (DUF3813)
JOLHEECK_01898 5e-73 ipi S Intracellular proteinase inhibitor
JOLHEECK_01899 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
JOLHEECK_01900 8.4e-159 yitS S protein conserved in bacteria
JOLHEECK_01901 1.6e-307 nprB 3.4.24.28 E Peptidase M4
JOLHEECK_01902 1.4e-44 yitR S Domain of unknown function (DUF3784)
JOLHEECK_01903 2e-95
JOLHEECK_01904 1.5e-58 K Transcriptional regulator PadR-like family
JOLHEECK_01905 1.5e-97 S Sporulation delaying protein SdpA
JOLHEECK_01906 1.4e-170
JOLHEECK_01907 8.5e-94
JOLHEECK_01908 6.9e-161 cvfB S protein conserved in bacteria
JOLHEECK_01909 5.6e-54 yajQ S Belongs to the UPF0234 family
JOLHEECK_01910 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
JOLHEECK_01911 7.8e-79 yjcF S Acetyltransferase (GNAT) domain
JOLHEECK_01912 2e-160 yitH K Acetyltransferase (GNAT) domain
JOLHEECK_01913 1.5e-228 yitG EGP Major facilitator Superfamily
JOLHEECK_01914 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
JOLHEECK_01915 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOLHEECK_01916 5.4e-141 yitD 4.4.1.19 S synthase
JOLHEECK_01917 5.3e-119 comB 3.1.3.71 H Belongs to the ComB family
JOLHEECK_01918 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
JOLHEECK_01919 2.5e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
JOLHEECK_01920 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
JOLHEECK_01921 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JOLHEECK_01922 4e-36 mcbG S Pentapeptide repeats (9 copies)
JOLHEECK_01923 1.8e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOLHEECK_01924 1.9e-107 argO S Lysine exporter protein LysE YggA
JOLHEECK_01925 7e-92 yisT S DinB family
JOLHEECK_01926 1.5e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
JOLHEECK_01927 1.5e-183 purR K helix_turn _helix lactose operon repressor
JOLHEECK_01928 1.2e-160 yisR K Transcriptional regulator
JOLHEECK_01929 1.5e-242 yisQ V Mate efflux family protein
JOLHEECK_01930 2.8e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
JOLHEECK_01931 3.9e-87 yizA S Damage-inducible protein DinB
JOLHEECK_01932 0.0 asnO 6.3.5.4 E Asparagine synthase
JOLHEECK_01933 2.1e-102 yisN S Protein of unknown function (DUF2777)
JOLHEECK_01934 0.0 wprA O Belongs to the peptidase S8 family
JOLHEECK_01935 3.9e-57 yisL S UPF0344 protein
JOLHEECK_01936 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
JOLHEECK_01937 1.1e-172 cotH M Spore Coat
JOLHEECK_01938 1.5e-22 yisI S Spo0E like sporulation regulatory protein
JOLHEECK_01939 1.9e-33 gerPA S Spore germination protein
JOLHEECK_01940 4e-34 gerPB S cell differentiation
JOLHEECK_01941 1.8e-54 gerPC S Spore germination protein
JOLHEECK_01942 6.3e-24 gerPD S Spore germination protein
JOLHEECK_01943 3e-66 gerPE S Spore germination protein GerPE
JOLHEECK_01944 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
JOLHEECK_01945 1.1e-49 yisB V COG1403 Restriction endonuclease
JOLHEECK_01946 0.0 sbcC L COG0419 ATPase involved in DNA repair
JOLHEECK_01947 6.9e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JOLHEECK_01948 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JOLHEECK_01949 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
JOLHEECK_01950 1.1e-77 yhjR S Rubrerythrin
JOLHEECK_01951 0.0 S Sugar transport-related sRNA regulator N-term
JOLHEECK_01952 7.9e-211 EGP Transmembrane secretion effector
JOLHEECK_01953 5.1e-199 abrB S membrane
JOLHEECK_01954 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
JOLHEECK_01955 7.7e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
JOLHEECK_01956 4.5e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
JOLHEECK_01957 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
JOLHEECK_01958 4.5e-214 glcP G Major Facilitator Superfamily
JOLHEECK_01959 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
JOLHEECK_01960 2.4e-278 yhjG CH FAD binding domain
JOLHEECK_01961 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
JOLHEECK_01962 3.4e-109 yhjE S SNARE associated Golgi protein
JOLHEECK_01963 6.7e-60 yhjD
JOLHEECK_01964 6.9e-27 yhjC S Protein of unknown function (DUF3311)
JOLHEECK_01965 1.3e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOLHEECK_01966 7.8e-42 yhjA S Excalibur calcium-binding domain
JOLHEECK_01967 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
JOLHEECK_01968 4.2e-109 comK K Competence transcription factor
JOLHEECK_01969 1.3e-32 yhzC S IDEAL
JOLHEECK_01970 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOLHEECK_01971 4.7e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
JOLHEECK_01972 1.7e-182 hemAT NT chemotaxis protein
JOLHEECK_01973 6.5e-91 bioY S BioY family
JOLHEECK_01974 6.4e-268 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
JOLHEECK_01975 5.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
JOLHEECK_01976 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
JOLHEECK_01977 4.3e-159 yfmC M Periplasmic binding protein
JOLHEECK_01978 5.4e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
JOLHEECK_01979 3.1e-75 VY92_01935 K acetyltransferase
JOLHEECK_01980 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
JOLHEECK_01981 3.5e-241 yhfN 3.4.24.84 O Peptidase M48
JOLHEECK_01982 1.9e-65 yhfM
JOLHEECK_01983 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
JOLHEECK_01984 1.9e-110 yhfK GM NmrA-like family
JOLHEECK_01985 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
JOLHEECK_01986 2e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
JOLHEECK_01987 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JOLHEECK_01988 1.7e-72 3.4.13.21 S ASCH
JOLHEECK_01989 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
JOLHEECK_01990 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
JOLHEECK_01991 4.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOLHEECK_01992 2.5e-237 yhgE S YhgE Pip N-terminal domain protein
JOLHEECK_01993 5.4e-101 yhgD K Transcriptional regulator
JOLHEECK_01994 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JOLHEECK_01995 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JOLHEECK_01996 1.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JOLHEECK_01997 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JOLHEECK_01998 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
JOLHEECK_01999 7.9e-27 1.15.1.2 C Rubrerythrin
JOLHEECK_02000 2.7e-231 yhfA C membrane
JOLHEECK_02001 5.7e-230 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
JOLHEECK_02002 1.4e-114 ecsC S EcsC protein family
JOLHEECK_02003 1.8e-215 ecsB U ABC transporter
JOLHEECK_02004 4.6e-137 ecsA V transporter (ATP-binding protein)
JOLHEECK_02005 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
JOLHEECK_02006 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JOLHEECK_02007 3.6e-80 trpP S Tryptophan transporter TrpP
JOLHEECK_02008 7e-39 yhaH S YtxH-like protein
JOLHEECK_02009 1e-113 hpr K Negative regulator of protease production and sporulation
JOLHEECK_02010 1.3e-54 yhaI S Protein of unknown function (DUF1878)
JOLHEECK_02011 8.7e-90 yhaK S Putative zincin peptidase
JOLHEECK_02012 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JOLHEECK_02013 1.6e-21 yhaL S Sporulation protein YhaL
JOLHEECK_02014 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
JOLHEECK_02015 0.0 yhaN L AAA domain
JOLHEECK_02016 2.2e-224 yhaO L DNA repair exonuclease
JOLHEECK_02017 1.6e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
JOLHEECK_02018 1.2e-166 yhaQ S ABC transporter, ATP-binding protein
JOLHEECK_02019 1.1e-26 S YhzD-like protein
JOLHEECK_02020 2.3e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
JOLHEECK_02022 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
JOLHEECK_02023 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
JOLHEECK_02024 3.9e-292 hemZ H coproporphyrinogen III oxidase
JOLHEECK_02025 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
JOLHEECK_02026 2e-205 yhaZ L DNA alkylation repair enzyme
JOLHEECK_02027 9.5e-48 yheA S Belongs to the UPF0342 family
JOLHEECK_02028 1.8e-201 yheB S Belongs to the UPF0754 family
JOLHEECK_02029 4.3e-216 yheC HJ YheC/D like ATP-grasp
JOLHEECK_02030 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
JOLHEECK_02031 1.3e-36 yheE S Family of unknown function (DUF5342)
JOLHEECK_02032 6.3e-28 sspB S spore protein
JOLHEECK_02033 7.6e-109 yheG GM NAD(P)H-binding
JOLHEECK_02034 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
JOLHEECK_02035 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
JOLHEECK_02036 5.4e-82 nhaX T Belongs to the universal stress protein A family
JOLHEECK_02037 3.7e-225 nhaC C Na H antiporter
JOLHEECK_02038 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
JOLHEECK_02039 5.3e-137 yheN G deacetylase
JOLHEECK_02040 4.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
JOLHEECK_02041 1.6e-202 yhdY M Mechanosensitive ion channel
JOLHEECK_02043 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JOLHEECK_02044 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JOLHEECK_02045 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JOLHEECK_02046 2.1e-239 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
JOLHEECK_02047 4.4e-222 yhdR 2.6.1.1 E Aminotransferase
JOLHEECK_02048 4.1e-74 cueR K transcriptional
JOLHEECK_02049 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JOLHEECK_02050 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
JOLHEECK_02051 1.7e-190 yhdN C Aldo keto reductase
JOLHEECK_02052 1e-84 sigM K Belongs to the sigma-70 factor family. ECF subfamily
JOLHEECK_02053 1.5e-200 yhdL S Sigma factor regulator N-terminal
JOLHEECK_02054 8.1e-45 yhdK S Sigma-M inhibitor protein
JOLHEECK_02055 2e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOLHEECK_02056 7.2e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOLHEECK_02057 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
JOLHEECK_02058 3.4e-250 yhdG E amino acid
JOLHEECK_02059 2.7e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOLHEECK_02060 1.3e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
JOLHEECK_02061 3.8e-162 citR K Transcriptional regulator
JOLHEECK_02062 1e-139 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JOLHEECK_02063 5e-254 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
JOLHEECK_02064 6.3e-276 ycgB S Stage V sporulation protein R
JOLHEECK_02065 3.6e-237 ygxB M Conserved TM helix
JOLHEECK_02066 1e-75 nsrR K Transcriptional regulator
JOLHEECK_02067 1.5e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JOLHEECK_02068 4.8e-54 yhdC S Protein of unknown function (DUF3889)
JOLHEECK_02069 1.2e-38 yhdB S YhdB-like protein
JOLHEECK_02070 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
JOLHEECK_02071 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOLHEECK_02072 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
JOLHEECK_02073 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
JOLHEECK_02074 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JOLHEECK_02075 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JOLHEECK_02076 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
JOLHEECK_02077 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JOLHEECK_02078 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JOLHEECK_02079 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JOLHEECK_02080 4.6e-120 yhcW 5.4.2.6 S hydrolase
JOLHEECK_02081 9.9e-68 yhcV S COG0517 FOG CBS domain
JOLHEECK_02082 9.3e-68 yhcU S Family of unknown function (DUF5365)
JOLHEECK_02083 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JOLHEECK_02084 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
JOLHEECK_02085 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
JOLHEECK_02086 5.2e-100 yhcQ M Spore coat protein
JOLHEECK_02087 2.5e-167 yhcP
JOLHEECK_02088 1.3e-67 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JOLHEECK_02089 2e-41 yhcM
JOLHEECK_02090 1.2e-49 K Transcriptional regulator PadR-like family
JOLHEECK_02091 1.1e-77 S Protein of unknown function (DUF2812)
JOLHEECK_02092 4.1e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JOLHEECK_02093 1.9e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
JOLHEECK_02094 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
JOLHEECK_02095 1e-30 cspB K Cold-shock protein
JOLHEECK_02096 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JOLHEECK_02097 6.5e-165 yhcH V ABC transporter, ATP-binding protein
JOLHEECK_02098 4.4e-121 yhcG V ABC transporter, ATP-binding protein
JOLHEECK_02099 1.5e-59 yhcF K Transcriptional regulator
JOLHEECK_02100 3.5e-55
JOLHEECK_02101 2.8e-37 yhcC
JOLHEECK_02102 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
JOLHEECK_02103 3.1e-271 yhcA EGP Major facilitator Superfamily
JOLHEECK_02104 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
JOLHEECK_02105 2.2e-76 yhbI K DNA-binding transcription factor activity
JOLHEECK_02106 2.5e-225 yhbH S Belongs to the UPF0229 family
JOLHEECK_02107 0.0 prkA T Ser protein kinase
JOLHEECK_02108 8.5e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
JOLHEECK_02109 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
JOLHEECK_02110 1.2e-109 yhbD K Protein of unknown function (DUF4004)
JOLHEECK_02111 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JOLHEECK_02112 4.4e-177 yhbB S Putative amidase domain
JOLHEECK_02113 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JOLHEECK_02114 7.9e-114 yhzB S B3/4 domain
JOLHEECK_02116 4.8e-29 K Transcriptional regulator
JOLHEECK_02117 4.1e-78 ygaO
JOLHEECK_02118 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JOLHEECK_02120 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
JOLHEECK_02121 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
JOLHEECK_02122 1.7e-171 ssuA M Sulfonate ABC transporter
JOLHEECK_02123 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
JOLHEECK_02124 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
JOLHEECK_02126 1.9e-266 ygaK C Berberine and berberine like
JOLHEECK_02127 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JOLHEECK_02128 1.6e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
JOLHEECK_02129 1.2e-26
JOLHEECK_02130 2.7e-143 spo0M S COG4326 Sporulation control protein
JOLHEECK_02134 2e-08
JOLHEECK_02142 7.8e-08
JOLHEECK_02147 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
JOLHEECK_02148 1.4e-92 M1-753 M FR47-like protein
JOLHEECK_02149 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
JOLHEECK_02150 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
JOLHEECK_02151 3.9e-84 yuaE S DinB superfamily
JOLHEECK_02152 7.4e-106 yuaD
JOLHEECK_02153 1.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
JOLHEECK_02154 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
JOLHEECK_02155 2.7e-94 yuaC K Belongs to the GbsR family
JOLHEECK_02156 2.2e-91 yuaB
JOLHEECK_02157 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
JOLHEECK_02158 1.6e-236 ktrB P Potassium
JOLHEECK_02159 1e-38 yiaA S yiaA/B two helix domain
JOLHEECK_02160 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JOLHEECK_02161 2.4e-273 yubD P Major Facilitator Superfamily
JOLHEECK_02162 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
JOLHEECK_02164 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
JOLHEECK_02165 1.3e-194 yubA S transporter activity
JOLHEECK_02166 3.3e-183 ygjR S Oxidoreductase
JOLHEECK_02167 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
JOLHEECK_02168 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
JOLHEECK_02169 5.1e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
JOLHEECK_02170 6.6e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
JOLHEECK_02171 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
JOLHEECK_02172 7.3e-238 mcpA NT chemotaxis protein
JOLHEECK_02173 4.7e-293 mcpA NT chemotaxis protein
JOLHEECK_02174 2.4e-220 mcpA NT chemotaxis protein
JOLHEECK_02175 3.2e-225 mcpA NT chemotaxis protein
JOLHEECK_02176 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
JOLHEECK_02177 2.3e-35
JOLHEECK_02178 1.8e-71 yugU S Uncharacterised protein family UPF0047
JOLHEECK_02179 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
JOLHEECK_02180 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
JOLHEECK_02181 1.4e-116 yugP S Zn-dependent protease
JOLHEECK_02182 2.3e-38
JOLHEECK_02183 1.1e-53 mstX S Membrane-integrating protein Mistic
JOLHEECK_02184 2.2e-182 yugO P COG1226 Kef-type K transport systems
JOLHEECK_02185 1.3e-72 yugN S YugN-like family
JOLHEECK_02187 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
JOLHEECK_02188 2.8e-229 yugK C Dehydrogenase
JOLHEECK_02189 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
JOLHEECK_02190 3.1e-34 yuzA S Domain of unknown function (DUF378)
JOLHEECK_02191 1.5e-62 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
JOLHEECK_02192 2.1e-199 yugH 2.6.1.1 E Aminotransferase
JOLHEECK_02193 1.6e-85 alaR K Transcriptional regulator
JOLHEECK_02194 4.9e-156 yugF I Hydrolase
JOLHEECK_02195 1.6e-39 yugE S Domain of unknown function (DUF1871)
JOLHEECK_02196 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
JOLHEECK_02197 4.6e-233 T PhoQ Sensor
JOLHEECK_02198 3.1e-68 kapB G Kinase associated protein B
JOLHEECK_02199 1.9e-115 kapD L the KinA pathway to sporulation
JOLHEECK_02201 3.8e-185 yuxJ EGP Major facilitator Superfamily
JOLHEECK_02202 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
JOLHEECK_02203 1.8e-74 yuxK S protein conserved in bacteria
JOLHEECK_02204 6.3e-78 yufK S Family of unknown function (DUF5366)
JOLHEECK_02205 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JOLHEECK_02206 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
JOLHEECK_02207 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
JOLHEECK_02208 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
JOLHEECK_02209 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
JOLHEECK_02210 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
JOLHEECK_02211 1.3e-233 maeN C COG3493 Na citrate symporter
JOLHEECK_02212 3.2e-14
JOLHEECK_02213 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
JOLHEECK_02214 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOLHEECK_02215 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOLHEECK_02216 6.4e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOLHEECK_02217 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOLHEECK_02218 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOLHEECK_02219 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
JOLHEECK_02220 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
JOLHEECK_02221 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOLHEECK_02222 0.0 comP 2.7.13.3 T Histidine kinase
JOLHEECK_02224 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
JOLHEECK_02227 3.2e-22 yuzC
JOLHEECK_02228 1.8e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
JOLHEECK_02229 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JOLHEECK_02230 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
JOLHEECK_02231 7.9e-67 yueI S Protein of unknown function (DUF1694)
JOLHEECK_02232 2.8e-38 yueH S YueH-like protein
JOLHEECK_02233 2.1e-32 yueG S Spore germination protein gerPA/gerPF
JOLHEECK_02234 1.9e-190 yueF S transporter activity
JOLHEECK_02235 6.1e-72 S Protein of unknown function (DUF2283)
JOLHEECK_02236 2.9e-24 S Protein of unknown function (DUF2642)
JOLHEECK_02237 4.8e-96 yueE S phosphohydrolase
JOLHEECK_02238 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOLHEECK_02239 6.6e-65 yueC S Family of unknown function (DUF5383)
JOLHEECK_02240 0.0 esaA S type VII secretion protein EsaA
JOLHEECK_02241 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
JOLHEECK_02242 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
JOLHEECK_02243 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
JOLHEECK_02244 2.8e-45 esxA S Belongs to the WXG100 family
JOLHEECK_02245 6.5e-229 yukF QT Transcriptional regulator
JOLHEECK_02246 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
JOLHEECK_02247 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
JOLHEECK_02248 3.8e-36 mbtH S MbtH-like protein
JOLHEECK_02249 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOLHEECK_02250 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
JOLHEECK_02251 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
JOLHEECK_02252 6.6e-226 entC 5.4.4.2 HQ Isochorismate synthase
JOLHEECK_02253 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOLHEECK_02254 1.3e-167 besA S Putative esterase
JOLHEECK_02255 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
JOLHEECK_02256 4.4e-93 bioY S Biotin biosynthesis protein
JOLHEECK_02257 3.9e-211 yuiF S antiporter
JOLHEECK_02258 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JOLHEECK_02259 1.2e-77 yuiD S protein conserved in bacteria
JOLHEECK_02260 5.6e-118 yuiC S protein conserved in bacteria
JOLHEECK_02261 8.4e-27 yuiB S Putative membrane protein
JOLHEECK_02262 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
JOLHEECK_02263 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
JOLHEECK_02265 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JOLHEECK_02266 1e-116 paiB K Putative FMN-binding domain
JOLHEECK_02267 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOLHEECK_02268 3.7e-63 erpA S Belongs to the HesB IscA family
JOLHEECK_02269 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JOLHEECK_02270 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOLHEECK_02271 3.2e-39 yuzB S Belongs to the UPF0349 family
JOLHEECK_02272 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
JOLHEECK_02273 3.5e-57 yuzD S protein conserved in bacteria
JOLHEECK_02274 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
JOLHEECK_02275 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
JOLHEECK_02276 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JOLHEECK_02277 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JOLHEECK_02278 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
JOLHEECK_02279 2.9e-198 yutH S Spore coat protein
JOLHEECK_02280 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
JOLHEECK_02281 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JOLHEECK_02282 8.6e-75 yutE S Protein of unknown function DUF86
JOLHEECK_02283 9.7e-48 yutD S protein conserved in bacteria
JOLHEECK_02284 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JOLHEECK_02285 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JOLHEECK_02286 3.8e-195 lytH M Peptidase, M23
JOLHEECK_02287 4.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
JOLHEECK_02288 5.3e-47 yunC S Domain of unknown function (DUF1805)
JOLHEECK_02289 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JOLHEECK_02290 1e-140 yunE S membrane transporter protein
JOLHEECK_02291 7.3e-171 yunF S Protein of unknown function DUF72
JOLHEECK_02292 6.7e-62 yunG
JOLHEECK_02293 7.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
JOLHEECK_02294 3.4e-302 pucR QT COG2508 Regulator of polyketide synthase expression
JOLHEECK_02295 2.1e-236 pbuX F Permease family
JOLHEECK_02296 1.3e-222 pbuX F xanthine
JOLHEECK_02297 7.3e-283 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
JOLHEECK_02298 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
JOLHEECK_02299 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
JOLHEECK_02300 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
JOLHEECK_02301 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
JOLHEECK_02302 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
JOLHEECK_02303 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JOLHEECK_02305 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
JOLHEECK_02306 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
JOLHEECK_02307 2.4e-169 bsn L Ribonuclease
JOLHEECK_02308 1.2e-205 msmX P Belongs to the ABC transporter superfamily
JOLHEECK_02309 1.1e-135 yurK K UTRA
JOLHEECK_02310 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
JOLHEECK_02311 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
JOLHEECK_02312 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
JOLHEECK_02313 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
JOLHEECK_02314 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
JOLHEECK_02315 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
JOLHEECK_02316 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
JOLHEECK_02318 1e-41
JOLHEECK_02319 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOLHEECK_02320 3.5e-271 sufB O FeS cluster assembly
JOLHEECK_02321 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
JOLHEECK_02322 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JOLHEECK_02323 9.1e-245 sufD O assembly protein SufD
JOLHEECK_02324 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
JOLHEECK_02325 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JOLHEECK_02326 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
JOLHEECK_02327 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
JOLHEECK_02328 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JOLHEECK_02329 2.4e-56 yusD S SCP-2 sterol transfer family
JOLHEECK_02330 5.6e-55 traF CO Thioredoxin
JOLHEECK_02331 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
JOLHEECK_02332 1.1e-39 yusG S Protein of unknown function (DUF2553)
JOLHEECK_02333 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
JOLHEECK_02334 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
JOLHEECK_02335 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
JOLHEECK_02336 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
JOLHEECK_02337 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
JOLHEECK_02338 8.1e-09 S YuzL-like protein
JOLHEECK_02339 7.1e-164 fadM E Proline dehydrogenase
JOLHEECK_02340 5.1e-40
JOLHEECK_02341 5.4e-53 yusN M Coat F domain
JOLHEECK_02342 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
JOLHEECK_02343 3.2e-292 yusP P Major facilitator superfamily
JOLHEECK_02344 2.7e-64 yusQ S Tautomerase enzyme
JOLHEECK_02345 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOLHEECK_02346 5.7e-158 yusT K LysR substrate binding domain
JOLHEECK_02347 3.8e-47 yusU S Protein of unknown function (DUF2573)
JOLHEECK_02348 1e-153 yusV 3.6.3.34 HP ABC transporter
JOLHEECK_02349 2.5e-66 S YusW-like protein
JOLHEECK_02350 1.9e-301 pepF2 E COG1164 Oligoendopeptidase F
JOLHEECK_02351 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOLHEECK_02352 1.2e-79 dps P Ferritin-like domain
JOLHEECK_02353 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOLHEECK_02354 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOLHEECK_02355 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
JOLHEECK_02356 4.3e-158 yuxN K Transcriptional regulator
JOLHEECK_02357 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
JOLHEECK_02358 2.3e-24 S Protein of unknown function (DUF3970)
JOLHEECK_02359 1.4e-246 gerAA EG Spore germination protein
JOLHEECK_02360 9.1e-198 gerAB E Spore germination protein
JOLHEECK_02361 3.3e-187 gerAC S Spore germination B3/ GerAC like, C-terminal
JOLHEECK_02362 8.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOLHEECK_02363 3.5e-186 vraS 2.7.13.3 T Histidine kinase
JOLHEECK_02364 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
JOLHEECK_02365 2.3e-127 liaG S Putative adhesin
JOLHEECK_02366 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
JOLHEECK_02367 5.6e-62 liaI S membrane
JOLHEECK_02368 1.4e-226 yvqJ EGP Major facilitator Superfamily
JOLHEECK_02369 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
JOLHEECK_02370 1.1e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
JOLHEECK_02371 1.6e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOLHEECK_02372 1.9e-167 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
JOLHEECK_02373 2.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOLHEECK_02374 2.9e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
JOLHEECK_02375 0.0 T PhoQ Sensor
JOLHEECK_02376 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOLHEECK_02377 3.6e-22
JOLHEECK_02378 9.5e-98 yvrI K RNA polymerase
JOLHEECK_02379 2.4e-19 S YvrJ protein family
JOLHEECK_02380 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
JOLHEECK_02381 3.8e-64 yvrL S Regulatory protein YrvL
JOLHEECK_02382 3.4e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
JOLHEECK_02383 2.1e-123 macB V ABC transporter, ATP-binding protein
JOLHEECK_02384 2.6e-174 M Efflux transporter rnd family, mfp subunit
JOLHEECK_02385 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
JOLHEECK_02386 3.4e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOLHEECK_02387 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOLHEECK_02388 7.6e-177 fhuD P ABC transporter
JOLHEECK_02390 4.9e-236 yvsH E Arginine ornithine antiporter
JOLHEECK_02391 6.5e-16 S Small spore protein J (Spore_SspJ)
JOLHEECK_02392 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
JOLHEECK_02393 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JOLHEECK_02394 1.1e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
JOLHEECK_02395 4.9e-137 modA P COG0725 ABC-type molybdate transport system, periplasmic component
JOLHEECK_02396 3.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
JOLHEECK_02397 2.2e-156 yvgN S reductase
JOLHEECK_02398 2.1e-85 yvgO
JOLHEECK_02399 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
JOLHEECK_02400 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
JOLHEECK_02401 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JOLHEECK_02402 0.0 helD 3.6.4.12 L DNA helicase
JOLHEECK_02404 2.7e-106 yvgT S membrane
JOLHEECK_02405 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
JOLHEECK_02406 1.6e-104 bdbD O Thioredoxin
JOLHEECK_02407 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
JOLHEECK_02408 0.0 copA 3.6.3.54 P P-type ATPase
JOLHEECK_02409 1.5e-29 copZ P Copper resistance protein CopZ
JOLHEECK_02410 2.2e-48 csoR S transcriptional
JOLHEECK_02411 3.1e-195 yvaA 1.1.1.371 S Oxidoreductase
JOLHEECK_02412 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JOLHEECK_02413 0.0 yvaC S Fusaric acid resistance protein-like
JOLHEECK_02414 1.3e-72 yvaD S Family of unknown function (DUF5360)
JOLHEECK_02415 6.3e-55 yvaE P Small Multidrug Resistance protein
JOLHEECK_02416 4.1e-101 K Bacterial regulatory proteins, tetR family
JOLHEECK_02417 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOLHEECK_02419 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JOLHEECK_02420 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JOLHEECK_02421 5.6e-143 est 3.1.1.1 S Carboxylesterase
JOLHEECK_02422 2.4e-23 secG U Preprotein translocase subunit SecG
JOLHEECK_02423 3.7e-153 yvaM S Serine aminopeptidase, S33
JOLHEECK_02424 7.5e-36 yvzC K Transcriptional
JOLHEECK_02425 2.2e-54 yodB K transcriptional
JOLHEECK_02426 1.1e-213 NT chemotaxis protein
JOLHEECK_02427 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
JOLHEECK_02428 8e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JOLHEECK_02429 5.6e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
JOLHEECK_02430 2.8e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
JOLHEECK_02431 3.3e-60 yvbF K Belongs to the GbsR family
JOLHEECK_02432 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
JOLHEECK_02433 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JOLHEECK_02434 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
JOLHEECK_02435 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
JOLHEECK_02436 3.5e-97 yvbF K Belongs to the GbsR family
JOLHEECK_02437 2.7e-101 yvbG U UPF0056 membrane protein
JOLHEECK_02438 8.6e-113 yvbH S YvbH-like oligomerisation region
JOLHEECK_02439 1.3e-120 exoY M Membrane
JOLHEECK_02440 0.0 tcaA S response to antibiotic
JOLHEECK_02441 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
JOLHEECK_02442 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JOLHEECK_02443 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
JOLHEECK_02444 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JOLHEECK_02445 3.8e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JOLHEECK_02446 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JOLHEECK_02447 2.6e-183 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
JOLHEECK_02448 1.6e-252 araE EGP Major facilitator Superfamily
JOLHEECK_02449 5.5e-203 araR K transcriptional
JOLHEECK_02450 4.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOLHEECK_02451 5.1e-159 yvbU K Transcriptional regulator
JOLHEECK_02452 7.2e-156 yvbV EG EamA-like transporter family
JOLHEECK_02453 3.7e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
JOLHEECK_02454 2.6e-194 yvbX S Glycosyl hydrolase
JOLHEECK_02455 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
JOLHEECK_02456 1.7e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
JOLHEECK_02457 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
JOLHEECK_02458 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOLHEECK_02459 1.6e-194 desK 2.7.13.3 T Histidine kinase
JOLHEECK_02460 6.9e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
JOLHEECK_02461 1.7e-157 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
JOLHEECK_02462 6.4e-156 rsbQ S Alpha/beta hydrolase family
JOLHEECK_02463 3.2e-196 rsbU 3.1.3.3 T response regulator
JOLHEECK_02464 2.3e-248 galA 3.2.1.89 G arabinogalactan
JOLHEECK_02465 0.0 lacA 3.2.1.23 G beta-galactosidase
JOLHEECK_02466 7.2e-150 ganQ P transport
JOLHEECK_02467 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
JOLHEECK_02468 4.4e-228 cycB G COG2182 Maltose-binding periplasmic proteins domains
JOLHEECK_02469 1.8e-184 lacR K Transcriptional regulator
JOLHEECK_02470 1e-112 yvfI K COG2186 Transcriptional regulators
JOLHEECK_02471 2.6e-308 yvfH C L-lactate permease
JOLHEECK_02472 1.2e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
JOLHEECK_02473 1e-31 yvfG S YvfG protein
JOLHEECK_02474 2.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
JOLHEECK_02475 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
JOLHEECK_02476 9e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
JOLHEECK_02477 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
JOLHEECK_02478 1.4e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOLHEECK_02479 2.7e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
JOLHEECK_02480 1.2e-202 epsI GM pyruvyl transferase
JOLHEECK_02481 9.8e-194 epsH GT2 S Glycosyltransferase like family 2
JOLHEECK_02482 7e-206 epsG S EpsG family
JOLHEECK_02483 8.4e-218 epsF GT4 M Glycosyl transferases group 1
JOLHEECK_02484 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JOLHEECK_02485 1.2e-221 epsD GT4 M Glycosyl transferase 4-like
JOLHEECK_02486 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
JOLHEECK_02487 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
JOLHEECK_02488 4e-122 ywqC M biosynthesis protein
JOLHEECK_02489 1.4e-75 slr K transcriptional
JOLHEECK_02490 1.6e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
JOLHEECK_02492 5.1e-92 padC Q Phenolic acid decarboxylase
JOLHEECK_02493 3.8e-73 MA20_18690 S Protein of unknown function (DUF3237)
JOLHEECK_02494 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
JOLHEECK_02495 3.2e-261 pbpE V Beta-lactamase
JOLHEECK_02496 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
JOLHEECK_02497 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
JOLHEECK_02498 1.8e-295 yveA E amino acid
JOLHEECK_02499 2.6e-106 yvdT K Transcriptional regulator
JOLHEECK_02500 1.9e-50 ykkC P Small Multidrug Resistance protein
JOLHEECK_02501 4.1e-50 sugE P Small Multidrug Resistance protein
JOLHEECK_02502 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
JOLHEECK_02503 1.1e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
JOLHEECK_02504 2.8e-182 S Patatin-like phospholipase
JOLHEECK_02506 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JOLHEECK_02507 2.8e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
JOLHEECK_02508 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
JOLHEECK_02509 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
JOLHEECK_02510 5e-154 malA S Protein of unknown function (DUF1189)
JOLHEECK_02511 3.9e-148 malD P transport
JOLHEECK_02512 5.9e-244 malC P COG1175 ABC-type sugar transport systems, permease components
JOLHEECK_02513 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
JOLHEECK_02514 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
JOLHEECK_02515 3.6e-174 yvdE K Transcriptional regulator
JOLHEECK_02516 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
JOLHEECK_02517 2.6e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
JOLHEECK_02518 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
JOLHEECK_02519 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
JOLHEECK_02520 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOLHEECK_02521 0.0 yxdM V ABC transporter (permease)
JOLHEECK_02522 5.6e-141 yvcR V ABC transporter, ATP-binding protein
JOLHEECK_02523 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
JOLHEECK_02524 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOLHEECK_02525 1.8e-33
JOLHEECK_02526 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
JOLHEECK_02527 1.6e-36 crh G Phosphocarrier protein Chr
JOLHEECK_02528 1.4e-170 whiA K May be required for sporulation
JOLHEECK_02529 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JOLHEECK_02530 5.7e-166 rapZ S Displays ATPase and GTPase activities
JOLHEECK_02531 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
JOLHEECK_02532 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JOLHEECK_02533 1.1e-97 usp CBM50 M protein conserved in bacteria
JOLHEECK_02534 4.5e-277 S COG0457 FOG TPR repeat
JOLHEECK_02535 0.0 msbA2 3.6.3.44 V ABC transporter
JOLHEECK_02537 0.0
JOLHEECK_02538 1.1e-73
JOLHEECK_02539 7.6e-65
JOLHEECK_02540 2.6e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
JOLHEECK_02541 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JOLHEECK_02542 5.8e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JOLHEECK_02543 7.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JOLHEECK_02544 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
JOLHEECK_02545 5.8e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JOLHEECK_02546 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
JOLHEECK_02547 1.3e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JOLHEECK_02548 3.8e-139 yvpB NU protein conserved in bacteria
JOLHEECK_02549 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
JOLHEECK_02550 7.3e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
JOLHEECK_02551 1.2e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
JOLHEECK_02552 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
JOLHEECK_02553 1.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JOLHEECK_02554 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JOLHEECK_02555 3.3e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JOLHEECK_02556 9.2e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JOLHEECK_02557 8.9e-133 yvoA K transcriptional
JOLHEECK_02558 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
JOLHEECK_02559 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
JOLHEECK_02560 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
JOLHEECK_02561 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
JOLHEECK_02562 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
JOLHEECK_02563 2.7e-203 yvmA EGP Major facilitator Superfamily
JOLHEECK_02564 1.2e-50 yvlD S Membrane
JOLHEECK_02565 2.6e-26 pspB KT PspC domain
JOLHEECK_02566 3.4e-168 yvlB S Putative adhesin
JOLHEECK_02567 8e-49 yvlA
JOLHEECK_02568 6.7e-34 yvkN
JOLHEECK_02569 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JOLHEECK_02570 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
JOLHEECK_02571 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JOLHEECK_02572 1.2e-30 csbA S protein conserved in bacteria
JOLHEECK_02573 0.0 yvkC 2.7.9.2 GT Phosphotransferase
JOLHEECK_02574 7e-101 yvkB K Transcriptional regulator
JOLHEECK_02575 7.9e-228 yvkA EGP Major facilitator Superfamily
JOLHEECK_02576 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOLHEECK_02577 5.3e-56 swrA S Swarming motility protein
JOLHEECK_02578 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
JOLHEECK_02579 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
JOLHEECK_02580 1.6e-123 ftsE D cell division ATP-binding protein FtsE
JOLHEECK_02581 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
JOLHEECK_02582 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
JOLHEECK_02583 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JOLHEECK_02584 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JOLHEECK_02585 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JOLHEECK_02586 5.4e-65
JOLHEECK_02587 1.9e-08 fliT S bacterial-type flagellum organization
JOLHEECK_02588 2.9e-69 fliS N flagellar protein FliS
JOLHEECK_02589 1.1e-265 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JOLHEECK_02590 6.1e-57 flaG N flagellar protein FlaG
JOLHEECK_02591 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JOLHEECK_02592 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JOLHEECK_02593 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JOLHEECK_02594 2.6e-50 yviE
JOLHEECK_02595 1.1e-156 flgL N Belongs to the bacterial flagellin family
JOLHEECK_02596 1.2e-264 flgK N flagellar hook-associated protein
JOLHEECK_02597 2.4e-78 flgN NOU FlgN protein
JOLHEECK_02598 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
JOLHEECK_02599 7e-74 yvyF S flagellar protein
JOLHEECK_02600 2.7e-129 comFC S Phosphoribosyl transferase domain
JOLHEECK_02601 5.7e-46 comFB S Late competence development protein ComFB
JOLHEECK_02602 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JOLHEECK_02603 7.3e-155 degV S protein conserved in bacteria
JOLHEECK_02604 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOLHEECK_02605 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
JOLHEECK_02606 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
JOLHEECK_02607 6e-163 yvhJ K Transcriptional regulator
JOLHEECK_02608 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
JOLHEECK_02609 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
JOLHEECK_02610 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
JOLHEECK_02611 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
JOLHEECK_02612 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
JOLHEECK_02613 4.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JOLHEECK_02614 7.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
JOLHEECK_02615 5.3e-246 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOLHEECK_02616 7.8e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
JOLHEECK_02617 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOLHEECK_02618 0.0 lytB 3.5.1.28 D Stage II sporulation protein
JOLHEECK_02619 6e-38
JOLHEECK_02620 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
JOLHEECK_02621 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JOLHEECK_02622 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JOLHEECK_02623 6.5e-57
JOLHEECK_02624 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
JOLHEECK_02625 7.5e-93 ggaA M Glycosyltransferase like family 2
JOLHEECK_02626 3e-39 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JOLHEECK_02627 1.9e-54 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JOLHEECK_02628 1.9e-36 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JOLHEECK_02629 9.2e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JOLHEECK_02630 4.1e-150 tagG GM Transport permease protein
JOLHEECK_02631 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JOLHEECK_02632 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
JOLHEECK_02633 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
JOLHEECK_02634 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
JOLHEECK_02635 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JOLHEECK_02636 3.5e-260
JOLHEECK_02637 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JOLHEECK_02638 5.7e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
JOLHEECK_02639 1.2e-261 gerBA EG Spore germination protein
JOLHEECK_02640 1.5e-192 gerBB E Spore germination protein
JOLHEECK_02641 7.1e-206 gerAC S Spore germination protein
JOLHEECK_02642 1.9e-248 ywtG EGP Major facilitator Superfamily
JOLHEECK_02643 8.4e-171 ywtF K Transcriptional regulator
JOLHEECK_02644 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
JOLHEECK_02645 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
JOLHEECK_02646 3.6e-21 ywtC
JOLHEECK_02647 1.1e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
JOLHEECK_02648 8.6e-70 pgsC S biosynthesis protein
JOLHEECK_02649 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
JOLHEECK_02650 9.3e-178 rbsR K transcriptional
JOLHEECK_02651 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOLHEECK_02652 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
JOLHEECK_02653 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
JOLHEECK_02654 2.1e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
JOLHEECK_02655 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
JOLHEECK_02656 8.7e-93 batE T Sh3 type 3 domain protein
JOLHEECK_02657 8e-48 ywsA S Protein of unknown function (DUF3892)
JOLHEECK_02658 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
JOLHEECK_02659 2.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
JOLHEECK_02660 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JOLHEECK_02661 1.1e-169 alsR K LysR substrate binding domain
JOLHEECK_02662 4.6e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JOLHEECK_02663 7.5e-126 ywrJ
JOLHEECK_02664 2.9e-130 cotB
JOLHEECK_02665 3.5e-210 cotH M Spore Coat
JOLHEECK_02666 3.7e-12
JOLHEECK_02667 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JOLHEECK_02668 1.4e-53 S Domain of unknown function (DUF4181)
JOLHEECK_02669 1.4e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
JOLHEECK_02670 8e-82 ywrC K Transcriptional regulator
JOLHEECK_02671 1.2e-103 ywrB P Chromate transporter
JOLHEECK_02672 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
JOLHEECK_02674 1.1e-100 ywqN S NAD(P)H-dependent
JOLHEECK_02675 1.4e-161 K Transcriptional regulator
JOLHEECK_02676 3.2e-119 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
JOLHEECK_02677 3.9e-25
JOLHEECK_02678 1.9e-82 ywqJ S Pre-toxin TG
JOLHEECK_02679 5.2e-17
JOLHEECK_02680 7.9e-43
JOLHEECK_02681 9.7e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
JOLHEECK_02682 8.6e-38 ywqI S Family of unknown function (DUF5344)
JOLHEECK_02683 9.7e-23 S Domain of unknown function (DUF5082)
JOLHEECK_02684 1.4e-152 ywqG S Domain of unknown function (DUF1963)
JOLHEECK_02685 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JOLHEECK_02686 5.1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
JOLHEECK_02687 5.8e-118 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
JOLHEECK_02688 2e-116 ywqC M biosynthesis protein
JOLHEECK_02689 1.2e-17
JOLHEECK_02690 1.4e-308 ywqB S SWIM zinc finger
JOLHEECK_02691 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
JOLHEECK_02692 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
JOLHEECK_02693 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
JOLHEECK_02694 3.7e-57 ssbB L Single-stranded DNA-binding protein
JOLHEECK_02695 3.8e-66 ywpG
JOLHEECK_02696 1.1e-66 ywpF S YwpF-like protein
JOLHEECK_02697 1.2e-49 srtA 3.4.22.70 M Sortase family
JOLHEECK_02698 7e-153 ywpD T Histidine kinase
JOLHEECK_02699 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JOLHEECK_02700 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JOLHEECK_02701 8.8e-198 S aspartate phosphatase
JOLHEECK_02702 3.7e-140 flhP N flagellar basal body
JOLHEECK_02703 9.9e-125 flhO N flagellar basal body
JOLHEECK_02704 3.5e-180 mbl D Rod shape-determining protein
JOLHEECK_02705 3e-44 spoIIID K Stage III sporulation protein D
JOLHEECK_02706 2.1e-70 ywoH K COG1846 Transcriptional regulators
JOLHEECK_02707 3.9e-210 ywoG EGP Major facilitator Superfamily
JOLHEECK_02708 2.8e-231 ywoF P Right handed beta helix region
JOLHEECK_02709 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
JOLHEECK_02710 9.8e-242 ywoD EGP Major facilitator superfamily
JOLHEECK_02711 4e-104 phzA Q Isochorismatase family
JOLHEECK_02712 2.2e-76
JOLHEECK_02713 2.5e-225 amt P Ammonium transporter
JOLHEECK_02714 1.6e-58 nrgB K Belongs to the P(II) protein family
JOLHEECK_02715 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
JOLHEECK_02716 3e-72 ywnJ S VanZ like family
JOLHEECK_02717 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
JOLHEECK_02718 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
JOLHEECK_02719 8.9e-10 ywnC S Family of unknown function (DUF5362)
JOLHEECK_02720 2.2e-70 ywnF S Family of unknown function (DUF5392)
JOLHEECK_02721 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOLHEECK_02722 5e-142 mta K transcriptional
JOLHEECK_02723 2.6e-59 ywnC S Family of unknown function (DUF5362)
JOLHEECK_02724 1.6e-114 ywnB S NAD(P)H-binding
JOLHEECK_02725 1.7e-64 ywnA K Transcriptional regulator
JOLHEECK_02726 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
JOLHEECK_02727 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
JOLHEECK_02728 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
JOLHEECK_02730 3.8e-11 csbD K CsbD-like
JOLHEECK_02731 3e-84 ywmF S Peptidase M50
JOLHEECK_02732 1.3e-103 S response regulator aspartate phosphatase
JOLHEECK_02733 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JOLHEECK_02734 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JOLHEECK_02736 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
JOLHEECK_02737 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
JOLHEECK_02738 1e-174 spoIID D Stage II sporulation protein D
JOLHEECK_02739 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JOLHEECK_02740 2.8e-134 ywmB S TATA-box binding
JOLHEECK_02741 1.3e-32 ywzB S membrane
JOLHEECK_02742 1.3e-60 ywmA
JOLHEECK_02743 1.4e-13 ywmA
JOLHEECK_02744 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JOLHEECK_02745 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JOLHEECK_02746 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JOLHEECK_02747 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JOLHEECK_02748 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JOLHEECK_02749 6.4e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JOLHEECK_02750 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JOLHEECK_02751 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
JOLHEECK_02752 2.5e-62 atpI S ATP synthase
JOLHEECK_02753 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JOLHEECK_02754 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JOLHEECK_02755 7.2e-95 ywlG S Belongs to the UPF0340 family
JOLHEECK_02756 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
JOLHEECK_02757 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JOLHEECK_02758 1.7e-91 mntP P Probably functions as a manganese efflux pump
JOLHEECK_02759 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JOLHEECK_02760 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
JOLHEECK_02761 6.1e-112 spoIIR S stage II sporulation protein R
JOLHEECK_02762 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
JOLHEECK_02764 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JOLHEECK_02765 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JOLHEECK_02766 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOLHEECK_02767 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
JOLHEECK_02768 8.6e-160 ywkB S Membrane transport protein
JOLHEECK_02769 0.0 sfcA 1.1.1.38 C malic enzyme
JOLHEECK_02770 1.6e-103 tdk 2.7.1.21 F thymidine kinase
JOLHEECK_02771 1.1e-32 rpmE J Binds the 23S rRNA
JOLHEECK_02772 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JOLHEECK_02773 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
JOLHEECK_02774 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JOLHEECK_02775 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JOLHEECK_02776 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
JOLHEECK_02777 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
JOLHEECK_02778 5.1e-90 ywjG S Domain of unknown function (DUF2529)
JOLHEECK_02779 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JOLHEECK_02780 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JOLHEECK_02781 1.3e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
JOLHEECK_02782 0.0 fadF C COG0247 Fe-S oxidoreductase
JOLHEECK_02783 1.5e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
JOLHEECK_02784 3.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
JOLHEECK_02785 2.7e-42 ywjC
JOLHEECK_02786 4.8e-96 ywjB H RibD C-terminal domain
JOLHEECK_02787 0.0 ywjA V ABC transporter
JOLHEECK_02788 2.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOLHEECK_02789 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
JOLHEECK_02790 1.1e-93 narJ 1.7.5.1 C nitrate reductase
JOLHEECK_02791 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
JOLHEECK_02792 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JOLHEECK_02793 7e-86 arfM T cyclic nucleotide binding
JOLHEECK_02794 1.7e-139 ywiC S YwiC-like protein
JOLHEECK_02795 7.7e-129 fnr K helix_turn_helix, cAMP Regulatory protein
JOLHEECK_02796 2.3e-213 narK P COG2223 Nitrate nitrite transporter
JOLHEECK_02797 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
JOLHEECK_02798 4.7e-73 ywiB S protein conserved in bacteria
JOLHEECK_02799 1e-07 S Bacteriocin subtilosin A
JOLHEECK_02800 4.9e-270 C Fe-S oxidoreductases
JOLHEECK_02802 3.3e-132 cbiO V ABC transporter
JOLHEECK_02803 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
JOLHEECK_02804 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
JOLHEECK_02805 1.6e-249 L Peptidase, M16
JOLHEECK_02807 4.7e-244 ywhL CO amine dehydrogenase activity
JOLHEECK_02808 3.2e-192 ywhK CO amine dehydrogenase activity
JOLHEECK_02809 8.9e-79 S aspartate phosphatase
JOLHEECK_02811 3.7e-28 ywhH S Aminoacyl-tRNA editing domain
JOLHEECK_02812 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
JOLHEECK_02813 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JOLHEECK_02814 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JOLHEECK_02815 3.6e-49
JOLHEECK_02816 5.2e-95 ywhD S YwhD family
JOLHEECK_02817 5.1e-119 ywhC S Peptidase family M50
JOLHEECK_02818 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
JOLHEECK_02819 9.5e-71 ywhA K Transcriptional regulator
JOLHEECK_02820 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JOLHEECK_02822 9.8e-237 mmr U Major Facilitator Superfamily
JOLHEECK_02823 6.2e-79 yffB K Transcriptional regulator
JOLHEECK_02824 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
JOLHEECK_02825 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
JOLHEECK_02826 3.1e-36 ywzC S Belongs to the UPF0741 family
JOLHEECK_02827 5.1e-110 rsfA_1
JOLHEECK_02828 1.6e-155 ywfM EG EamA-like transporter family
JOLHEECK_02829 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
JOLHEECK_02830 1.1e-156 cysL K Transcriptional regulator
JOLHEECK_02831 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
JOLHEECK_02832 1.1e-146 ywfI C May function as heme-dependent peroxidase
JOLHEECK_02833 1.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
JOLHEECK_02834 5e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
JOLHEECK_02835 1.9e-209 bacE EGP Major facilitator Superfamily
JOLHEECK_02836 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
JOLHEECK_02837 2.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOLHEECK_02838 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
JOLHEECK_02839 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
JOLHEECK_02840 6e-206 ywfA EGP Major facilitator Superfamily
JOLHEECK_02841 4.8e-249 lysP E amino acid
JOLHEECK_02842 0.0 rocB E arginine degradation protein
JOLHEECK_02843 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
JOLHEECK_02844 8.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
JOLHEECK_02845 3.4e-77
JOLHEECK_02846 1.3e-86 spsL 5.1.3.13 M Spore Coat
JOLHEECK_02847 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JOLHEECK_02848 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JOLHEECK_02849 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JOLHEECK_02850 1.5e-183 spsG M Spore Coat
JOLHEECK_02851 1e-128 spsF M Spore Coat
JOLHEECK_02852 6e-213 spsE 2.5.1.56 M acid synthase
JOLHEECK_02853 1.7e-162 spsD 2.3.1.210 K Spore Coat
JOLHEECK_02854 1.1e-222 spsC E Belongs to the DegT DnrJ EryC1 family
JOLHEECK_02855 1.4e-267 spsB M Capsule polysaccharide biosynthesis protein
JOLHEECK_02856 4.5e-143 spsA M Spore Coat
JOLHEECK_02857 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
JOLHEECK_02858 4.3e-59 ywdK S small membrane protein
JOLHEECK_02859 3.7e-238 ywdJ F Xanthine uracil
JOLHEECK_02860 6.6e-48 ywdI S Family of unknown function (DUF5327)
JOLHEECK_02861 3e-259 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
JOLHEECK_02862 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JOLHEECK_02863 1.6e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
JOLHEECK_02864 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JOLHEECK_02865 2e-28 ywdA
JOLHEECK_02866 1.4e-283 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
JOLHEECK_02867 1.8e-251 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOLHEECK_02868 6.7e-139 focA P Formate/nitrite transporter
JOLHEECK_02869 7e-150 sacT K transcriptional antiterminator
JOLHEECK_02871 0.0 vpr O Belongs to the peptidase S8 family
JOLHEECK_02872 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOLHEECK_02873 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
JOLHEECK_02874 8.6e-202 rodA D Belongs to the SEDS family
JOLHEECK_02875 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
JOLHEECK_02876 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
JOLHEECK_02877 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
JOLHEECK_02878 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JOLHEECK_02879 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
JOLHEECK_02880 1e-35 ywzA S membrane
JOLHEECK_02881 2.6e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JOLHEECK_02882 1.9e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JOLHEECK_02883 9.5e-60 gtcA S GtrA-like protein
JOLHEECK_02884 1.1e-121 ywcC K transcriptional regulator
JOLHEECK_02886 9.8e-49 ywcB S Protein of unknown function, DUF485
JOLHEECK_02887 6.9e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOLHEECK_02888 4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
JOLHEECK_02889 3.2e-223 ywbN P Dyp-type peroxidase family protein
JOLHEECK_02890 2e-163 ycdO P periplasmic lipoprotein involved in iron transport
JOLHEECK_02891 9e-254 P COG0672 High-affinity Fe2 Pb2 permease
JOLHEECK_02892 4.5e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
JOLHEECK_02893 1.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JOLHEECK_02894 4.3e-153 ywbI K Transcriptional regulator
JOLHEECK_02895 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
JOLHEECK_02896 2.3e-111 ywbG M effector of murein hydrolase
JOLHEECK_02897 8.1e-208 ywbF EGP Major facilitator Superfamily
JOLHEECK_02898 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
JOLHEECK_02899 3.5e-219 ywbD 2.1.1.191 J Methyltransferase
JOLHEECK_02900 9.9e-67 ywbC 4.4.1.5 E glyoxalase
JOLHEECK_02901 6.9e-96 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
JOLHEECK_02902 8.3e-125 ywbB S Protein of unknown function (DUF2711)
JOLHEECK_02903 1.4e-240 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOLHEECK_02904 2.9e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
JOLHEECK_02905 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOLHEECK_02906 7.6e-152 sacY K transcriptional antiterminator
JOLHEECK_02907 4.5e-168 gspA M General stress
JOLHEECK_02908 1.5e-124 ywaF S Integral membrane protein
JOLHEECK_02909 1.2e-86 ywaE K Transcriptional regulator
JOLHEECK_02910 3.9e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JOLHEECK_02911 3.7e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
JOLHEECK_02912 4e-92 K Helix-turn-helix XRE-family like proteins
JOLHEECK_02913 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
JOLHEECK_02914 8.8e-130 ynfM EGP Major facilitator Superfamily
JOLHEECK_02915 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
JOLHEECK_02916 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
JOLHEECK_02917 5e-14 S D-Ala-teichoic acid biosynthesis protein
JOLHEECK_02918 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOLHEECK_02919 3.6e-232 dltB M membrane protein involved in D-alanine export
JOLHEECK_02920 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOLHEECK_02921 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JOLHEECK_02922 8.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
JOLHEECK_02923 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
JOLHEECK_02924 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
JOLHEECK_02925 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
JOLHEECK_02926 7e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOLHEECK_02927 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
JOLHEECK_02928 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
JOLHEECK_02929 1.1e-19 yxzF
JOLHEECK_02930 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
JOLHEECK_02931 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
JOLHEECK_02932 1.6e-211 yxlH EGP Major facilitator Superfamily
JOLHEECK_02933 2.6e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JOLHEECK_02934 8.2e-165 yxlF V ABC transporter, ATP-binding protein
JOLHEECK_02935 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
JOLHEECK_02936 1.4e-30
JOLHEECK_02937 1.6e-46 yxlC S Family of unknown function (DUF5345)
JOLHEECK_02938 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
JOLHEECK_02939 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
JOLHEECK_02940 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JOLHEECK_02941 0.0 cydD V ATP-binding protein
JOLHEECK_02942 4e-309 cydD V ATP-binding
JOLHEECK_02943 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
JOLHEECK_02944 6.9e-267 cydA 1.10.3.14 C oxidase, subunit
JOLHEECK_02945 2.1e-228 cimH C COG3493 Na citrate symporter
JOLHEECK_02946 2.3e-309 3.4.24.84 O Peptidase family M48
JOLHEECK_02948 9.9e-152 yxkH G Polysaccharide deacetylase
JOLHEECK_02949 5.9e-205 msmK P Belongs to the ABC transporter superfamily
JOLHEECK_02950 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
JOLHEECK_02951 2.5e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JOLHEECK_02952 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOLHEECK_02953 2.8e-74 yxkC S Domain of unknown function (DUF4352)
JOLHEECK_02954 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JOLHEECK_02955 7.7e-77 S Protein of unknown function (DUF1453)
JOLHEECK_02956 1.6e-190 yxjM T Signal transduction histidine kinase
JOLHEECK_02957 9.8e-115 K helix_turn_helix, Lux Regulon
JOLHEECK_02958 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JOLHEECK_02960 1.4e-86 yxjI S LURP-one-related
JOLHEECK_02961 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
JOLHEECK_02962 1e-220 yxjG 2.1.1.14 E Methionine synthase
JOLHEECK_02963 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
JOLHEECK_02964 3.4e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
JOLHEECK_02965 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JOLHEECK_02966 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
JOLHEECK_02967 5e-142 rlmA 2.1.1.187 Q Methyltransferase domain
JOLHEECK_02968 5.4e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOLHEECK_02969 1.5e-102 T Domain of unknown function (DUF4163)
JOLHEECK_02970 3e-47 yxiS
JOLHEECK_02971 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
JOLHEECK_02972 6.6e-224 citH C Citrate transporter
JOLHEECK_02973 3.6e-142 exoK GH16 M licheninase activity
JOLHEECK_02974 8.3e-151 licT K transcriptional antiterminator
JOLHEECK_02975 2e-110
JOLHEECK_02976 5.6e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
JOLHEECK_02977 5.6e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
JOLHEECK_02978 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
JOLHEECK_02981 1.6e-48 yxiJ S YxiJ-like protein
JOLHEECK_02982 3e-90 yxiI S Protein of unknown function (DUF2716)
JOLHEECK_02983 3.8e-81
JOLHEECK_02984 4.9e-46
JOLHEECK_02985 3.7e-75 yxiG
JOLHEECK_02986 6.4e-63
JOLHEECK_02987 1.7e-84
JOLHEECK_02988 1.5e-71 yxxG
JOLHEECK_02989 0.0 wapA M COG3209 Rhs family protein
JOLHEECK_02990 2.9e-168 yxxF EG EamA-like transporter family
JOLHEECK_02991 1.1e-72 yxiE T Belongs to the universal stress protein A family
JOLHEECK_02992 6.2e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JOLHEECK_02993 4.3e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOLHEECK_02994 3.6e-51
JOLHEECK_02995 2.2e-78 S SMI1 / KNR4 family
JOLHEECK_02996 0.0 S nuclease activity
JOLHEECK_02997 3.6e-39 yxiC S Family of unknown function (DUF5344)
JOLHEECK_02998 2.1e-21 S Domain of unknown function (DUF5082)
JOLHEECK_02999 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
JOLHEECK_03000 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
JOLHEECK_03001 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
JOLHEECK_03002 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JOLHEECK_03003 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
JOLHEECK_03004 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
JOLHEECK_03005 1.3e-249 lysP E amino acid
JOLHEECK_03006 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
JOLHEECK_03007 8.3e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOLHEECK_03008 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JOLHEECK_03009 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
JOLHEECK_03010 1.3e-151 yxxB S Domain of Unknown Function (DUF1206)
JOLHEECK_03011 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
JOLHEECK_03012 2e-255 yxeQ S MmgE/PrpD family
JOLHEECK_03013 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
JOLHEECK_03014 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
JOLHEECK_03015 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
JOLHEECK_03016 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
JOLHEECK_03017 7.5e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOLHEECK_03018 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOLHEECK_03020 1.2e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
JOLHEECK_03021 1.4e-150 yidA S hydrolases of the HAD superfamily
JOLHEECK_03024 1.3e-20 yxeE
JOLHEECK_03025 1.9e-16 yxeD
JOLHEECK_03026 8.5e-69
JOLHEECK_03027 1.9e-175 fhuD P ABC transporter
JOLHEECK_03028 1.5e-58 yxeA S Protein of unknown function (DUF1093)
JOLHEECK_03029 0.0 yxdM V ABC transporter (permease)
JOLHEECK_03030 9.4e-141 yxdL V ABC transporter, ATP-binding protein
JOLHEECK_03031 4.8e-182 T PhoQ Sensor
JOLHEECK_03032 1.2e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOLHEECK_03033 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
JOLHEECK_03034 2.3e-137 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
JOLHEECK_03035 8.6e-167 iolH G Xylose isomerase-like TIM barrel
JOLHEECK_03036 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
JOLHEECK_03037 5.1e-235 iolF EGP Major facilitator Superfamily
JOLHEECK_03038 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
JOLHEECK_03039 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
JOLHEECK_03040 1.4e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
JOLHEECK_03041 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
JOLHEECK_03042 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JOLHEECK_03043 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
JOLHEECK_03044 8.3e-176 iolS C Aldo keto reductase
JOLHEECK_03046 8.3e-48 yxcD S Protein of unknown function (DUF2653)
JOLHEECK_03047 2.3e-246 csbC EGP Major facilitator Superfamily
JOLHEECK_03048 0.0 htpG O Molecular chaperone. Has ATPase activity
JOLHEECK_03050 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
JOLHEECK_03051 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
JOLHEECK_03052 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
JOLHEECK_03053 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
JOLHEECK_03054 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
JOLHEECK_03055 3.3e-127 yxbB Q Met-10+ like-protein
JOLHEECK_03056 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
JOLHEECK_03057 1.1e-86 yxnB
JOLHEECK_03058 0.0 asnB 6.3.5.4 E Asparagine synthase
JOLHEECK_03059 7.6e-214 yxaM U MFS_1 like family
JOLHEECK_03060 6.8e-93 S PQQ-like domain
JOLHEECK_03061 3.5e-65 S Family of unknown function (DUF5391)
JOLHEECK_03062 1.1e-75 yxaI S membrane protein domain
JOLHEECK_03063 1.4e-228 P Protein of unknown function (DUF418)
JOLHEECK_03064 1.3e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
JOLHEECK_03065 1.2e-100 yxaF K Transcriptional regulator
JOLHEECK_03066 1.9e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOLHEECK_03067 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
JOLHEECK_03068 5.2e-50 S LrgA family
JOLHEECK_03069 1.3e-117 yxaC M effector of murein hydrolase
JOLHEECK_03070 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
JOLHEECK_03071 1.9e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JOLHEECK_03072 2.8e-126 gntR K transcriptional
JOLHEECK_03073 2.8e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
JOLHEECK_03074 1e-230 gntP EG COG2610 H gluconate symporter and related permeases
JOLHEECK_03075 5e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JOLHEECK_03076 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
JOLHEECK_03077 1.9e-286 ahpF O Alkyl hydroperoxide reductase
JOLHEECK_03078 5.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JOLHEECK_03079 3.4e-27 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
JOLHEECK_03080 1.9e-124 yydK K Transcriptional regulator
JOLHEECK_03081 1.6e-118 S ABC-2 family transporter protein
JOLHEECK_03082 1.6e-109 prrC P ABC transporter
JOLHEECK_03083 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
JOLHEECK_03084 1.3e-202 S SIR2-like domain
JOLHEECK_03085 1.1e-180 L DNA synthesis involved in DNA repair
JOLHEECK_03086 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JOLHEECK_03087 1.1e-09 S YyzF-like protein
JOLHEECK_03088 1.3e-67
JOLHEECK_03089 3.9e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
JOLHEECK_03091 1.7e-30 yycQ S Protein of unknown function (DUF2651)
JOLHEECK_03092 5.4e-201 yycP
JOLHEECK_03093 8.4e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
JOLHEECK_03094 1.4e-83 yycN 2.3.1.128 K Acetyltransferase
JOLHEECK_03095 1.1e-187 S aspartate phosphatase
JOLHEECK_03097 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
JOLHEECK_03098 1.3e-260 rocE E amino acid
JOLHEECK_03099 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
JOLHEECK_03100 7.4e-16
JOLHEECK_03101 2.8e-94
JOLHEECK_03102 2.3e-24 S Sporulation delaying protein SdpA
JOLHEECK_03103 1.5e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
JOLHEECK_03104 1.5e-40 sdpR K transcriptional
JOLHEECK_03105 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
JOLHEECK_03106 2.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
JOLHEECK_03107 1.5e-94 K PFAM response regulator receiver
JOLHEECK_03108 2.6e-73 S Peptidase propeptide and YPEB domain
JOLHEECK_03109 5.5e-33 S Peptidase propeptide and YPEB domain
JOLHEECK_03110 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOLHEECK_03111 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
JOLHEECK_03112 1.8e-153 yycI S protein conserved in bacteria
JOLHEECK_03113 3.1e-259 yycH S protein conserved in bacteria
JOLHEECK_03114 0.0 vicK 2.7.13.3 T Histidine kinase
JOLHEECK_03115 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOLHEECK_03120 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JOLHEECK_03121 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOLHEECK_03122 1.2e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JOLHEECK_03123 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
JOLHEECK_03125 1.9e-15 yycC K YycC-like protein
JOLHEECK_03126 8.4e-221 yeaN P COG2807 Cyanate permease
JOLHEECK_03127 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JOLHEECK_03128 2.2e-73 rplI J binds to the 23S rRNA
JOLHEECK_03129 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JOLHEECK_03130 8.3e-160 yybS S membrane
JOLHEECK_03132 3.3e-83 cotF M Spore coat protein
JOLHEECK_03133 1.7e-66 ydeP3 K Transcriptional regulator
JOLHEECK_03134 8.1e-163 ppaC 3.6.1.1 C Inorganic pyrophosphatase
JOLHEECK_03135 3.6e-60
JOLHEECK_03137 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
JOLHEECK_03138 2.2e-110 K TipAS antibiotic-recognition domain
JOLHEECK_03139 4.8e-124
JOLHEECK_03140 2.9e-66 yybH S SnoaL-like domain
JOLHEECK_03141 3.5e-54 yybG S Pentapeptide repeat-containing protein
JOLHEECK_03142 2.2e-216 ynfM EGP Major facilitator Superfamily
JOLHEECK_03143 4e-164 yybE K Transcriptional regulator
JOLHEECK_03144 7.7e-79 yjcF S Acetyltransferase (GNAT) domain
JOLHEECK_03145 1.6e-74 yybC
JOLHEECK_03146 7.3e-126 S Metallo-beta-lactamase superfamily
JOLHEECK_03147 5.6e-77 yybA 2.3.1.57 K transcriptional
JOLHEECK_03148 2e-71 yjcF S Acetyltransferase (GNAT) domain
JOLHEECK_03149 5.5e-96 yyaS S Membrane
JOLHEECK_03150 1.6e-91 yyaR K Acetyltransferase (GNAT) domain
JOLHEECK_03151 1.3e-65 yyaQ S YjbR
JOLHEECK_03152 2.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
JOLHEECK_03153 6.6e-246 tetL EGP Major facilitator Superfamily
JOLHEECK_03154 2.3e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
JOLHEECK_03156 4.1e-11 S Putative amidase domain
JOLHEECK_03157 5.1e-61 yyaN K MerR HTH family regulatory protein
JOLHEECK_03158 2.8e-160 yyaM EG EamA-like transporter family
JOLHEECK_03159 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
JOLHEECK_03160 3.6e-168 yyaK S CAAX protease self-immunity
JOLHEECK_03161 2.3e-243 EGP Major facilitator superfamily
JOLHEECK_03162 1.1e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
JOLHEECK_03163 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOLHEECK_03164 8.9e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
JOLHEECK_03165 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
JOLHEECK_03166 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JOLHEECK_03167 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JOLHEECK_03168 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
JOLHEECK_03169 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JOLHEECK_03170 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JOLHEECK_03171 2.3e-33 yyzM S protein conserved in bacteria
JOLHEECK_03172 8.1e-177 yyaD S Membrane
JOLHEECK_03173 1.6e-111 yyaC S Sporulation protein YyaC
JOLHEECK_03174 2.1e-149 spo0J K Belongs to the ParB family
JOLHEECK_03175 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
JOLHEECK_03176 9.6e-74 S Bacterial PH domain
JOLHEECK_03177 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
JOLHEECK_03178 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
JOLHEECK_03179 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JOLHEECK_03180 5.8e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JOLHEECK_03181 6.5e-108 jag S single-stranded nucleic acid binding R3H
JOLHEECK_03182 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JOLHEECK_03183 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JOLHEECK_03184 7.8e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JOLHEECK_03185 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JOLHEECK_03186 2.4e-33 yaaA S S4 domain
JOLHEECK_03187 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JOLHEECK_03188 1.8e-37 yaaB S Domain of unknown function (DUF370)
JOLHEECK_03189 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOLHEECK_03190 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOLHEECK_03191 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
JOLHEECK_03193 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
JOLHEECK_03194 2.2e-142 ybbA S Putative esterase
JOLHEECK_03195 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOLHEECK_03196 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOLHEECK_03197 1.4e-165 feuA P Iron-uptake system-binding protein
JOLHEECK_03198 5e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
JOLHEECK_03199 4.1e-239 ybbC 3.2.1.52 S protein conserved in bacteria
JOLHEECK_03200 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
JOLHEECK_03201 4.2e-225 yfeW 3.4.16.4 V Belongs to the UPF0214 family
JOLHEECK_03202 1.4e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOLHEECK_03203 2.1e-149 ybbH K transcriptional
JOLHEECK_03204 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JOLHEECK_03205 1.9e-86 ybbJ J acetyltransferase
JOLHEECK_03206 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
JOLHEECK_03212 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
JOLHEECK_03213 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
JOLHEECK_03214 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JOLHEECK_03215 1.5e-224 ybbR S protein conserved in bacteria
JOLHEECK_03216 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JOLHEECK_03217 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JOLHEECK_03218 1.5e-174 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JOLHEECK_03219 5.8e-120 adaA 3.2.2.21 K Transcriptional regulator
JOLHEECK_03220 1.2e-97 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JOLHEECK_03221 1.8e-276 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
JOLHEECK_03222 0.0 ybcC S Belongs to the UPF0753 family
JOLHEECK_03223 4.7e-91 can 4.2.1.1 P carbonic anhydrase
JOLHEECK_03225 5.6e-46
JOLHEECK_03226 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
JOLHEECK_03227 5.1e-50 ybzH K Helix-turn-helix domain
JOLHEECK_03228 4.2e-201 ybcL EGP Major facilitator Superfamily
JOLHEECK_03230 9.1e-239 J 4Fe-4S single cluster domain
JOLHEECK_03231 1.6e-277 V CAAX protease self-immunity
JOLHEECK_03232 1.9e-135 skfE V ABC transporter
JOLHEECK_03233 4e-248 skfF S ABC transporter
JOLHEECK_03234 7.8e-91 C HEAT repeats
JOLHEECK_03235 1.1e-77 txn CO Thioredoxin-like
JOLHEECK_03236 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JOLHEECK_03237 3.8e-122 T Transcriptional regulatory protein, C terminal
JOLHEECK_03238 1.8e-168 T His Kinase A (phospho-acceptor) domain
JOLHEECK_03240 3.9e-139 KLT Protein tyrosine kinase
JOLHEECK_03241 8.5e-151 ybdN
JOLHEECK_03242 1.5e-214 ybdO S Domain of unknown function (DUF4885)
JOLHEECK_03243 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
JOLHEECK_03244 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
JOLHEECK_03245 4.9e-30 ybxH S Family of unknown function (DUF5370)
JOLHEECK_03246 1.8e-150 ybxI 3.5.2.6 V beta-lactamase
JOLHEECK_03247 7.6e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
JOLHEECK_03248 4.9e-41 ybyB
JOLHEECK_03249 8.8e-290 ybeC E amino acid
JOLHEECK_03250 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JOLHEECK_03251 7.3e-258 glpT G -transporter
JOLHEECK_03252 2.9e-35 S Protein of unknown function (DUF2651)
JOLHEECK_03253 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
JOLHEECK_03254 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
JOLHEECK_03256 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
JOLHEECK_03257 3.7e-160 ybfH EG EamA-like transporter family
JOLHEECK_03258 5.2e-145 msmR K AraC-like ligand binding domain
JOLHEECK_03259 2.2e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JOLHEECK_03260 2.9e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
JOLHEECK_03262 1e-167 S Alpha/beta hydrolase family
JOLHEECK_03263 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JOLHEECK_03264 2.7e-85 ybfM S SNARE associated Golgi protein
JOLHEECK_03265 6.9e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
JOLHEECK_03266 2e-45 ybfN
JOLHEECK_03267 3.3e-191 yceA S Belongs to the UPF0176 family
JOLHEECK_03268 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JOLHEECK_03269 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOLHEECK_03270 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JOLHEECK_03271 4.9e-128 K UTRA
JOLHEECK_03273 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
JOLHEECK_03274 1.4e-259 mmuP E amino acid
JOLHEECK_03275 1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
JOLHEECK_03276 2.8e-255 agcS E Sodium alanine symporter
JOLHEECK_03277 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
JOLHEECK_03278 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
JOLHEECK_03279 2.6e-169 glnL T Regulator
JOLHEECK_03280 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
JOLHEECK_03281 3.2e-270 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JOLHEECK_03282 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
JOLHEECK_03283 1.2e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
JOLHEECK_03284 2.1e-123 ycbG K FCD
JOLHEECK_03285 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
JOLHEECK_03286 8.6e-167 ycbJ S Macrolide 2'-phosphotransferase
JOLHEECK_03287 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
JOLHEECK_03288 5.4e-167 eamA1 EG spore germination
JOLHEECK_03289 8.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOLHEECK_03290 4.2e-167 T PhoQ Sensor
JOLHEECK_03291 3.5e-166 ycbN V ABC transporter, ATP-binding protein
JOLHEECK_03292 1.8e-114 S ABC-2 family transporter protein
JOLHEECK_03293 8.2e-53 ycbP S Protein of unknown function (DUF2512)
JOLHEECK_03294 2.8e-78 sleB 3.5.1.28 M Cell wall
JOLHEECK_03295 3.6e-134 ycbR T vWA found in TerF C terminus
JOLHEECK_03296 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
JOLHEECK_03297 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
JOLHEECK_03298 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JOLHEECK_03299 6.9e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JOLHEECK_03300 2.9e-199 ycbU E Selenocysteine lyase
JOLHEECK_03301 3e-225 lmrB EGP the major facilitator superfamily
JOLHEECK_03302 4.8e-102 yxaF K Transcriptional regulator
JOLHEECK_03303 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
JOLHEECK_03304 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
JOLHEECK_03305 4.9e-58 S RDD family
JOLHEECK_03306 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
JOLHEECK_03307 1.2e-156 2.7.13.3 T GHKL domain
JOLHEECK_03308 1.2e-126 lytR_2 T LytTr DNA-binding domain
JOLHEECK_03309 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
JOLHEECK_03310 2.7e-200 natB CP ABC-2 family transporter protein
JOLHEECK_03311 1.7e-22 yccK C Aldo keto reductase
JOLHEECK_03312 1e-142 yccK C Aldo keto reductase
JOLHEECK_03313 6.6e-177 ycdA S Domain of unknown function (DUF5105)
JOLHEECK_03314 4.2e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
JOLHEECK_03315 1.5e-259 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
JOLHEECK_03316 2.1e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
JOLHEECK_03317 6.1e-173 S response regulator aspartate phosphatase
JOLHEECK_03318 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
JOLHEECK_03319 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
JOLHEECK_03320 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
JOLHEECK_03321 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
JOLHEECK_03322 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
JOLHEECK_03323 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOLHEECK_03324 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
JOLHEECK_03325 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
JOLHEECK_03326 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
JOLHEECK_03327 6.3e-137 terC P Protein of unknown function (DUF475)
JOLHEECK_03328 0.0 yceG S Putative component of 'biosynthetic module'
JOLHEECK_03329 2e-192 yceH P Belongs to the TelA family
JOLHEECK_03330 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
JOLHEECK_03331 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
JOLHEECK_03332 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
JOLHEECK_03333 5.1e-229 proV 3.6.3.32 E glycine betaine
JOLHEECK_03334 1.3e-127 opuAB P glycine betaine
JOLHEECK_03335 1.5e-163 opuAC E glycine betaine
JOLHEECK_03336 1.9e-217 amhX S amidohydrolase
JOLHEECK_03337 1.1e-256 ycgA S Membrane
JOLHEECK_03338 4.1e-81 ycgB
JOLHEECK_03339 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
JOLHEECK_03340 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JOLHEECK_03341 3e-290 lctP C L-lactate permease
JOLHEECK_03342 1.8e-260 mdr EGP Major facilitator Superfamily
JOLHEECK_03343 2.9e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
JOLHEECK_03344 2e-112 ycgF E Lysine exporter protein LysE YggA
JOLHEECK_03345 7.6e-151 yqcI S YqcI/YcgG family
JOLHEECK_03346 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
JOLHEECK_03347 2.4e-112 ycgI S Domain of unknown function (DUF1989)
JOLHEECK_03348 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JOLHEECK_03349 2.5e-109 tmrB S AAA domain
JOLHEECK_03350 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JOLHEECK_03351 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
JOLHEECK_03352 1.2e-177 oxyR3 K LysR substrate binding domain
JOLHEECK_03353 9.4e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
JOLHEECK_03354 4.1e-144 ycgL S Predicted nucleotidyltransferase
JOLHEECK_03355 5.1e-170 ycgM E Proline dehydrogenase
JOLHEECK_03356 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
JOLHEECK_03357 2e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOLHEECK_03358 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
JOLHEECK_03359 9.1e-145 ycgQ S membrane
JOLHEECK_03360 9.1e-140 ycgR S permeases
JOLHEECK_03361 1.6e-157 I alpha/beta hydrolase fold
JOLHEECK_03362 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
JOLHEECK_03363 3e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
JOLHEECK_03364 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
JOLHEECK_03365 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JOLHEECK_03366 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JOLHEECK_03367 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
JOLHEECK_03368 1.4e-220 nasA P COG2223 Nitrate nitrite transporter
JOLHEECK_03369 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
JOLHEECK_03370 5.5e-109 yciB M ErfK YbiS YcfS YnhG
JOLHEECK_03371 4.6e-227 yciC S GTPases (G3E family)
JOLHEECK_03372 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
JOLHEECK_03373 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
JOLHEECK_03376 6.2e-76 yckC S membrane
JOLHEECK_03377 7.8e-52 yckD S Protein of unknown function (DUF2680)
JOLHEECK_03378 8e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JOLHEECK_03379 6.5e-69 nin S Competence protein J (ComJ)
JOLHEECK_03380 3e-70 nucA M Deoxyribonuclease NucA/NucB
JOLHEECK_03381 1.9e-186 tlpC 2.7.13.3 NT chemotaxis protein
JOLHEECK_03382 3e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
JOLHEECK_03383 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
JOLHEECK_03384 1.3e-63 hxlR K transcriptional
JOLHEECK_03385 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOLHEECK_03386 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOLHEECK_03387 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
JOLHEECK_03388 6.4e-139 srfAD Q thioesterase
JOLHEECK_03389 6.1e-227 EGP Major Facilitator Superfamily
JOLHEECK_03390 2.3e-88 S YcxB-like protein
JOLHEECK_03391 6.4e-160 ycxC EG EamA-like transporter family
JOLHEECK_03392 5.6e-250 ycxD K GntR family transcriptional regulator
JOLHEECK_03393 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
JOLHEECK_03394 1.7e-114 yczE S membrane
JOLHEECK_03395 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JOLHEECK_03396 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
JOLHEECK_03397 1.3e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
JOLHEECK_03398 4.9e-162 bsdA K LysR substrate binding domain
JOLHEECK_03399 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
JOLHEECK_03400 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
JOLHEECK_03401 4e-39 bsdD 4.1.1.61 S response to toxic substance
JOLHEECK_03402 2.3e-81 yclD
JOLHEECK_03403 1.9e-158 yclE 3.4.11.5 S Alpha beta hydrolase
JOLHEECK_03404 7.3e-267 dtpT E amino acid peptide transporter
JOLHEECK_03405 5.9e-292 yclG M Pectate lyase superfamily protein
JOLHEECK_03407 1.9e-276 gerKA EG Spore germination protein
JOLHEECK_03408 8e-227 gerKC S spore germination
JOLHEECK_03409 1e-196 gerKB F Spore germination protein
JOLHEECK_03410 5.6e-121 yclH P ABC transporter
JOLHEECK_03411 1.1e-195 yclI V ABC transporter (permease) YclI
JOLHEECK_03412 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOLHEECK_03413 5.2e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
JOLHEECK_03414 2e-70 S aspartate phosphatase
JOLHEECK_03417 5.7e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
JOLHEECK_03418 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOLHEECK_03419 1.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOLHEECK_03420 1.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
JOLHEECK_03421 1.4e-170 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
JOLHEECK_03422 1.4e-251 ycnB EGP Major facilitator Superfamily
JOLHEECK_03423 7.9e-152 ycnC K Transcriptional regulator
JOLHEECK_03424 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
JOLHEECK_03425 1.6e-45 ycnE S Monooxygenase
JOLHEECK_03426 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
JOLHEECK_03427 5.6e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOLHEECK_03428 2e-244 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JOLHEECK_03429 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JOLHEECK_03430 1.8e-148 glcU U Glucose uptake
JOLHEECK_03431 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOLHEECK_03432 2.9e-100 ycnI S protein conserved in bacteria
JOLHEECK_03433 4.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
JOLHEECK_03434 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
JOLHEECK_03435 7.3e-56
JOLHEECK_03436 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
JOLHEECK_03437 4.4e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
JOLHEECK_03438 9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
JOLHEECK_03439 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
JOLHEECK_03440 4.1e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JOLHEECK_03441 1.3e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JOLHEECK_03442 6.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
JOLHEECK_03443 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
JOLHEECK_03445 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JOLHEECK_03446 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
JOLHEECK_03447 2.1e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
JOLHEECK_03448 2.8e-148 ycsI S Belongs to the D-glutamate cyclase family
JOLHEECK_03449 1.2e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
JOLHEECK_03450 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
JOLHEECK_03451 1.2e-132 kipR K Transcriptional regulator
JOLHEECK_03452 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
JOLHEECK_03454 1.4e-49 yczJ S biosynthesis
JOLHEECK_03455 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
JOLHEECK_03456 2.4e-172 ydhF S Oxidoreductase
JOLHEECK_03457 0.0 mtlR K transcriptional regulator, MtlR
JOLHEECK_03458 2.1e-293 ydaB IQ acyl-CoA ligase
JOLHEECK_03459 9e-99 ydaC Q Methyltransferase domain
JOLHEECK_03460 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOLHEECK_03461 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
JOLHEECK_03462 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JOLHEECK_03463 6.8e-77 ydaG 1.4.3.5 S general stress protein
JOLHEECK_03464 1e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
JOLHEECK_03465 3.3e-46 ydzA EGP Major facilitator Superfamily
JOLHEECK_03466 2.5e-74 lrpC K Transcriptional regulator
JOLHEECK_03467 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JOLHEECK_03468 7.4e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
JOLHEECK_03469 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
JOLHEECK_03470 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
JOLHEECK_03471 4.5e-233 ydaM M Glycosyl transferase family group 2
JOLHEECK_03472 0.0 ydaN S Bacterial cellulose synthase subunit
JOLHEECK_03473 0.0 ydaO E amino acid
JOLHEECK_03474 1.9e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
JOLHEECK_03475 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JOLHEECK_03476 2.1e-39
JOLHEECK_03477 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
JOLHEECK_03479 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
JOLHEECK_03480 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
JOLHEECK_03482 8.9e-59 ydbB G Cupin domain
JOLHEECK_03483 3.1e-62 ydbC S Domain of unknown function (DUF4937
JOLHEECK_03484 3.5e-154 ydbD P Catalase
JOLHEECK_03485 5.1e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
JOLHEECK_03486 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JOLHEECK_03487 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
JOLHEECK_03488 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JOLHEECK_03489 9.7e-181 ydbI S AI-2E family transporter
JOLHEECK_03490 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
JOLHEECK_03491 1.6e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JOLHEECK_03492 2.7e-52 ydbL
JOLHEECK_03493 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
JOLHEECK_03494 1.1e-18 S Fur-regulated basic protein B
JOLHEECK_03495 2.2e-07 S Fur-regulated basic protein A
JOLHEECK_03496 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOLHEECK_03497 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JOLHEECK_03498 3.3e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JOLHEECK_03499 5.3e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JOLHEECK_03500 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JOLHEECK_03501 2.1e-82 ydbS S Bacterial PH domain
JOLHEECK_03502 3.9e-260 ydbT S Membrane
JOLHEECK_03503 1.2e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
JOLHEECK_03504 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JOLHEECK_03505 5.5e-182 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
JOLHEECK_03506 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JOLHEECK_03507 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
JOLHEECK_03508 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
JOLHEECK_03509 3.7e-143 rsbR T Positive regulator of sigma-B
JOLHEECK_03510 5.2e-57 rsbS T antagonist
JOLHEECK_03511 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
JOLHEECK_03512 9.3e-189 rsbU 3.1.3.3 KT phosphatase
JOLHEECK_03513 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
JOLHEECK_03514 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
JOLHEECK_03515 1.1e-136 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOLHEECK_03516 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
JOLHEECK_03517 0.0 yhgF K COG2183 Transcriptional accessory protein
JOLHEECK_03518 2.6e-82 ydcK S Belongs to the SprT family
JOLHEECK_03526 3.2e-114 yecA E amino acid
JOLHEECK_03527 4.6e-107 K Transcriptional regulator
JOLHEECK_03528 2.5e-74 rimJ2 J Acetyltransferase (GNAT) domain
JOLHEECK_03529 8.5e-45
JOLHEECK_03530 3.3e-138 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
JOLHEECK_03531 1.7e-32 K Helix-turn-helix XRE-family like proteins
JOLHEECK_03532 9.6e-40
JOLHEECK_03536 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
JOLHEECK_03537 8.7e-30 cspL K Cold shock
JOLHEECK_03538 1.5e-77 carD K Transcription factor
JOLHEECK_03539 1.3e-106 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JOLHEECK_03540 2.2e-15 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JOLHEECK_03541 1.4e-164 rhaS5 K AraC-like ligand binding domain
JOLHEECK_03542 3.2e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JOLHEECK_03543 1.4e-164 ydeE K AraC family transcriptional regulator
JOLHEECK_03544 1.1e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOLHEECK_03545 1.8e-216 ydeG EGP Major facilitator superfamily
JOLHEECK_03546 2.7e-45 ydeH
JOLHEECK_03547 2.4e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
JOLHEECK_03548 1.3e-109
JOLHEECK_03549 1.1e-31 S SNARE associated Golgi protein
JOLHEECK_03550 1.8e-14 ptsH G PTS HPr component phosphorylation site
JOLHEECK_03551 3.4e-84 K Transcriptional regulator C-terminal region
JOLHEECK_03552 2e-152 ydeK EG -transporter
JOLHEECK_03553 8.7e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOLHEECK_03554 1.3e-72 maoC I N-terminal half of MaoC dehydratase
JOLHEECK_03555 1.8e-104 ydeN S Serine hydrolase
JOLHEECK_03556 5.7e-55 K HxlR-like helix-turn-helix
JOLHEECK_03557 6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
JOLHEECK_03558 1.8e-68 ydeP K Transcriptional regulator
JOLHEECK_03559 1.7e-110 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
JOLHEECK_03560 1.5e-185 ydeR EGP Major facilitator Superfamily
JOLHEECK_03561 2.5e-104 ydeS K Transcriptional regulator
JOLHEECK_03562 1.8e-56 arsR K transcriptional
JOLHEECK_03563 2.6e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JOLHEECK_03564 7.2e-149 ydfB J GNAT acetyltransferase
JOLHEECK_03565 1e-162 ydfC EG EamA-like transporter family
JOLHEECK_03566 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOLHEECK_03567 3.8e-116 ydfE S Flavin reductase like domain
JOLHEECK_03568 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
JOLHEECK_03569 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JOLHEECK_03571 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
JOLHEECK_03572 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOLHEECK_03573 0.0 ydfJ S drug exporters of the RND superfamily
JOLHEECK_03574 1.9e-177 S Alpha/beta hydrolase family
JOLHEECK_03575 5.9e-118 S Protein of unknown function (DUF554)
JOLHEECK_03576 3.2e-147 K Bacterial transcription activator, effector binding domain
JOLHEECK_03577 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOLHEECK_03578 9.6e-112 ydfN C nitroreductase
JOLHEECK_03579 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
JOLHEECK_03580 8.8e-63 mhqP S DoxX
JOLHEECK_03581 1.3e-57 traF CO Thioredoxin
JOLHEECK_03582 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
JOLHEECK_03583 6.3e-29
JOLHEECK_03585 4.4e-118 ydfR S Protein of unknown function (DUF421)
JOLHEECK_03586 5.2e-122 ydfS S Protein of unknown function (DUF421)
JOLHEECK_03587 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
JOLHEECK_03588 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
JOLHEECK_03589 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
JOLHEECK_03590 3e-94 K Bacterial regulatory proteins, tetR family
JOLHEECK_03591 1.6e-52 S DoxX-like family
JOLHEECK_03592 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
JOLHEECK_03593 5.1e-134 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
JOLHEECK_03594 2e-119 purR K helix_turn _helix lactose operon repressor
JOLHEECK_03595 1e-190 csbC EGP Major facilitator Superfamily
JOLHEECK_03596 4.4e-104 G Xylose isomerase-like TIM barrel
JOLHEECK_03597 1.7e-301 expZ S ABC transporter
JOLHEECK_03598 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
JOLHEECK_03599 2.3e-90 dinB S DinB family
JOLHEECK_03600 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
JOLHEECK_03601 0.0 ydgH S drug exporters of the RND superfamily
JOLHEECK_03602 8.8e-113 drgA C nitroreductase
JOLHEECK_03603 2.4e-69 ydgJ K Winged helix DNA-binding domain
JOLHEECK_03604 4.8e-208 tcaB EGP Major facilitator Superfamily
JOLHEECK_03605 1.6e-121 ydhB S membrane transporter protein
JOLHEECK_03606 6.5e-122 ydhC K FCD
JOLHEECK_03607 6.3e-243 ydhD M Glycosyl hydrolase
JOLHEECK_03608 2.9e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
JOLHEECK_03609 4.2e-127
JOLHEECK_03610 2.6e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
JOLHEECK_03611 8.7e-68 frataxin S Domain of unknown function (DU1801)
JOLHEECK_03613 1.5e-80 K Acetyltransferase (GNAT) domain
JOLHEECK_03614 1e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
JOLHEECK_03615 2.5e-98 ydhK M Protein of unknown function (DUF1541)
JOLHEECK_03616 4.6e-200 pbuE EGP Major facilitator Superfamily
JOLHEECK_03617 4.2e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
JOLHEECK_03618 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
JOLHEECK_03619 9.8e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOLHEECK_03620 7.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JOLHEECK_03621 7.4e-132 ydhQ K UTRA
JOLHEECK_03622 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
JOLHEECK_03623 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
JOLHEECK_03624 9e-214 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
JOLHEECK_03625 6.1e-157 ydhU P Catalase
JOLHEECK_03628 1.7e-30 csfB S Inhibitor of sigma-G Gin
JOLHEECK_03629 2.4e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
JOLHEECK_03630 1.4e-201 yaaN P Belongs to the TelA family
JOLHEECK_03631 2.7e-274 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
JOLHEECK_03632 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JOLHEECK_03633 2.2e-54 yaaQ S protein conserved in bacteria
JOLHEECK_03634 1.5e-71 yaaR S protein conserved in bacteria
JOLHEECK_03635 1.1e-181 holB 2.7.7.7 L DNA polymerase III
JOLHEECK_03636 6.1e-146 yaaT S stage 0 sporulation protein
JOLHEECK_03637 4.8e-31 yabA L Involved in initiation control of chromosome replication
JOLHEECK_03638 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
JOLHEECK_03639 2.8e-48 yazA L endonuclease containing a URI domain
JOLHEECK_03640 1e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JOLHEECK_03641 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
JOLHEECK_03642 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JOLHEECK_03643 1.2e-143 tatD L hydrolase, TatD
JOLHEECK_03644 2e-167 rpfB GH23 T protein conserved in bacteria
JOLHEECK_03645 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JOLHEECK_03646 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JOLHEECK_03647 1.6e-136 yabG S peptidase
JOLHEECK_03648 7.8e-39 veg S protein conserved in bacteria
JOLHEECK_03649 8.3e-27 sspF S DNA topological change
JOLHEECK_03650 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JOLHEECK_03651 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
JOLHEECK_03652 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
JOLHEECK_03653 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
JOLHEECK_03654 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JOLHEECK_03655 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JOLHEECK_03656 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JOLHEECK_03657 2.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JOLHEECK_03658 2.4e-39 yabK S Peptide ABC transporter permease
JOLHEECK_03659 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JOLHEECK_03660 1.5e-92 spoVT K stage V sporulation protein
JOLHEECK_03661 2.1e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOLHEECK_03662 3e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
JOLHEECK_03663 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
JOLHEECK_03664 1.5e-49 yabP S Sporulation protein YabP
JOLHEECK_03665 2.5e-107 yabQ S spore cortex biosynthesis protein
JOLHEECK_03666 1.1e-44 divIC D Septum formation initiator
JOLHEECK_03667 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
JOLHEECK_03670 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
JOLHEECK_03671 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
JOLHEECK_03672 3.7e-185 KLT serine threonine protein kinase
JOLHEECK_03673 4.2e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JOLHEECK_03674 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JOLHEECK_03675 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JOLHEECK_03676 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JOLHEECK_03677 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JOLHEECK_03678 4.4e-135 yacD 5.2.1.8 O peptidyl-prolyl isomerase
JOLHEECK_03679 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JOLHEECK_03680 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JOLHEECK_03681 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
JOLHEECK_03682 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
JOLHEECK_03683 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JOLHEECK_03684 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JOLHEECK_03685 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JOLHEECK_03686 4.1e-30 yazB K transcriptional
JOLHEECK_03687 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOLHEECK_03688 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JOLHEECK_03689 3.3e-166 ygxA S Nucleotidyltransferase-like
JOLHEECK_03690 1.1e-54 ygzB S UPF0295 protein
JOLHEECK_03691 4e-80 perR P Belongs to the Fur family
JOLHEECK_03692 6.3e-87 bcp 1.11.1.15 O Peroxiredoxin
JOLHEECK_03693 1.2e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
JOLHEECK_03694 8.7e-180 ygaE S Membrane
JOLHEECK_03695 1.8e-301 ygaD V ABC transporter
JOLHEECK_03696 1.3e-104 ygaC J Belongs to the UPF0374 family
JOLHEECK_03697 1.5e-37 ygaB S YgaB-like protein
JOLHEECK_03698 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
JOLHEECK_03699 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOLHEECK_03700 6.9e-36 yfhS
JOLHEECK_03701 3.3e-210 mutY L A G-specific
JOLHEECK_03702 1.2e-185 yfhP S membrane-bound metal-dependent
JOLHEECK_03703 0.0 yfhO S Bacterial membrane protein YfhO
JOLHEECK_03704 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JOLHEECK_03705 1.3e-170 yfhM S Alpha beta hydrolase
JOLHEECK_03706 3.5e-51 yfhL S SdpI/YhfL protein family
JOLHEECK_03707 2.4e-87 batE T Bacterial SH3 domain homologues
JOLHEECK_03708 2.9e-44 yfhJ S WVELL protein
JOLHEECK_03709 6.2e-20 sspK S reproduction
JOLHEECK_03710 1.1e-209 yfhI EGP Major facilitator Superfamily
JOLHEECK_03712 9.7e-52 yfhH S Protein of unknown function (DUF1811)
JOLHEECK_03713 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
JOLHEECK_03714 1.6e-171 yfhF S nucleoside-diphosphate sugar epimerase
JOLHEECK_03716 2.1e-25 yfhD S YfhD-like protein
JOLHEECK_03717 1.5e-106 yfhC C nitroreductase
JOLHEECK_03718 1.8e-167 yfhB 5.3.3.17 S PhzF family
JOLHEECK_03719 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOLHEECK_03720 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOLHEECK_03721 1e-176 yfiY P ABC transporter substrate-binding protein
JOLHEECK_03722 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JOLHEECK_03723 5.8e-80 yfiV K transcriptional
JOLHEECK_03724 3.4e-283 yfiU EGP Major facilitator Superfamily
JOLHEECK_03725 3.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
JOLHEECK_03726 1.5e-209 yfiS EGP Major facilitator Superfamily
JOLHEECK_03727 7.1e-107 yfiR K Transcriptional regulator
JOLHEECK_03728 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JOLHEECK_03729 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
JOLHEECK_03730 8.3e-99 padR K transcriptional
JOLHEECK_03731 2.6e-203 V COG0842 ABC-type multidrug transport system, permease component
JOLHEECK_03732 2e-206 V ABC-2 family transporter protein
JOLHEECK_03733 1.4e-170 V ABC transporter, ATP-binding protein
JOLHEECK_03734 3.2e-113 KT LuxR family transcriptional regulator
JOLHEECK_03735 1.1e-214 yxjM T Histidine kinase
JOLHEECK_03737 1.1e-233 S Oxidoreductase
JOLHEECK_03738 8.4e-184 G Xylose isomerase
JOLHEECK_03739 1.8e-262 iolT EGP Major facilitator Superfamily
JOLHEECK_03740 1.5e-177 K AraC-like ligand binding domain
JOLHEECK_03741 5.7e-163 yfiE 1.13.11.2 S glyoxalase
JOLHEECK_03742 6.4e-64 mhqP S DoxX
JOLHEECK_03743 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
JOLHEECK_03744 8.4e-307 yfiB3 V ABC transporter
JOLHEECK_03745 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOLHEECK_03746 1.6e-140 glvR K Helix-turn-helix domain, rpiR family
JOLHEECK_03747 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
JOLHEECK_03748 7.4e-44 yfjA S Belongs to the WXG100 family
JOLHEECK_03749 9.2e-191 yfjB
JOLHEECK_03750 4.5e-143 yfjC
JOLHEECK_03751 1.8e-101 yfjD S Family of unknown function (DUF5381)
JOLHEECK_03752 1.1e-79 S Family of unknown function (DUF5381)
JOLHEECK_03753 4e-56 yfjF S UPF0060 membrane protein
JOLHEECK_03754 8.3e-24 sspH S Belongs to the SspH family
JOLHEECK_03755 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
JOLHEECK_03756 2.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JOLHEECK_03757 6.7e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JOLHEECK_03758 7.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JOLHEECK_03759 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JOLHEECK_03760 1.1e-83 yfjM S Psort location Cytoplasmic, score
JOLHEECK_03761 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOLHEECK_03762 1.6e-39 S YfzA-like protein
JOLHEECK_03763 4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JOLHEECK_03764 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JOLHEECK_03765 1.7e-184 corA P Mediates influx of magnesium ions
JOLHEECK_03766 9.8e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
JOLHEECK_03767 1.7e-153 pdaA G deacetylase
JOLHEECK_03768 1.1e-26 yfjT
JOLHEECK_03769 5.4e-222 yfkA S YfkB-like domain
JOLHEECK_03770 6e-149 yfkC M Mechanosensitive ion channel
JOLHEECK_03771 1.2e-146 yfkD S YfkD-like protein
JOLHEECK_03772 1.8e-182 cax P COG0387 Ca2 H antiporter
JOLHEECK_03773 2.6e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
JOLHEECK_03774 5e-08
JOLHEECK_03775 4.8e-143 yihY S Belongs to the UPF0761 family
JOLHEECK_03776 1.2e-49 yfkI S gas vesicle protein
JOLHEECK_03777 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JOLHEECK_03778 1.3e-28 yfkK S Belongs to the UPF0435 family
JOLHEECK_03779 6.8e-207 ydiM EGP Major facilitator Superfamily
JOLHEECK_03780 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
JOLHEECK_03781 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JOLHEECK_03782 1.8e-124 yfkO C nitroreductase
JOLHEECK_03783 5.1e-133 treR K transcriptional
JOLHEECK_03784 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JOLHEECK_03785 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOLHEECK_03786 1.9e-24 yfkQ EG Spore germination protein
JOLHEECK_03787 3.1e-251 agcS_1 E Sodium alanine symporter
JOLHEECK_03788 6e-67 yhdN S Domain of unknown function (DUF1992)
JOLHEECK_03789 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JOLHEECK_03790 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
JOLHEECK_03791 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
JOLHEECK_03792 5.3e-50 yflH S Protein of unknown function (DUF3243)
JOLHEECK_03793 4.1e-19 yflI
JOLHEECK_03794 4e-18 yflJ S Protein of unknown function (DUF2639)
JOLHEECK_03795 6.4e-122 yflK S protein conserved in bacteria
JOLHEECK_03796 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JOLHEECK_03797 2.1e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JOLHEECK_03798 2.3e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
JOLHEECK_03799 1.9e-226 citM C Citrate transporter
JOLHEECK_03800 4.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
JOLHEECK_03801 8.9e-119 citT T response regulator
JOLHEECK_03802 1.5e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JOLHEECK_03803 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
JOLHEECK_03804 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
JOLHEECK_03805 7.6e-58 yflT S Heat induced stress protein YflT
JOLHEECK_03806 2.9e-24 S Protein of unknown function (DUF3212)
JOLHEECK_03807 2.7e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
JOLHEECK_03808 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOLHEECK_03809 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOLHEECK_03810 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
JOLHEECK_03811 1.8e-187 yfmJ S N-terminal domain of oxidoreductase
JOLHEECK_03812 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
JOLHEECK_03813 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
JOLHEECK_03814 2.1e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JOLHEECK_03815 1.5e-209 yfmO EGP Major facilitator Superfamily
JOLHEECK_03816 4e-69 yfmP K transcriptional
JOLHEECK_03817 3.4e-74 yfmQ S Uncharacterised protein from bacillus cereus group
JOLHEECK_03818 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JOLHEECK_03819 1.1e-113 yfmS NT chemotaxis protein
JOLHEECK_03820 1.1e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JOLHEECK_03821 1.4e-240 yfnA E amino acid
JOLHEECK_03822 3.9e-133 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
JOLHEECK_03823 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
JOLHEECK_03824 3.3e-188 yfnD M Nucleotide-diphospho-sugar transferase
JOLHEECK_03825 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
JOLHEECK_03826 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
JOLHEECK_03827 1.9e-172 yfnG 4.2.1.45 M dehydratase
JOLHEECK_03828 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
JOLHEECK_03829 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JOLHEECK_03830 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
JOLHEECK_03831 3.6e-199 yetN S Protein of unknown function (DUF3900)
JOLHEECK_03832 8.3e-31 yetM CH FAD binding domain
JOLHEECK_03833 2.6e-104 yetJ S Belongs to the BI1 family
JOLHEECK_03834 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
JOLHEECK_03835 5.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JOLHEECK_03836 2.2e-34
JOLHEECK_03837 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOLHEECK_03838 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
JOLHEECK_03839 4e-122 yetF S membrane
JOLHEECK_03840 8.9e-256 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
JOLHEECK_03841 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
JOLHEECK_03842 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
JOLHEECK_03843 1.5e-288 lplA G Bacterial extracellular solute-binding protein
JOLHEECK_03844 0.0 yetA
JOLHEECK_03845 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
JOLHEECK_03846 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
JOLHEECK_03847 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
JOLHEECK_03848 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
JOLHEECK_03849 2.2e-111 yesV S Protein of unknown function, DUF624
JOLHEECK_03850 3e-127 yesU S Domain of unknown function (DUF1961)
JOLHEECK_03851 5.1e-130 E GDSL-like Lipase/Acylhydrolase
JOLHEECK_03852 0.0 yesS K Transcriptional regulator
JOLHEECK_03853 3.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
JOLHEECK_03854 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
JOLHEECK_03855 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
JOLHEECK_03856 1.6e-246 yesO G Bacterial extracellular solute-binding protein
JOLHEECK_03857 1.4e-201 yesN K helix_turn_helix, arabinose operon control protein
JOLHEECK_03858 0.0 yesM 2.7.13.3 T Histidine kinase
JOLHEECK_03859 1.2e-101 yesL S Protein of unknown function, DUF624
JOLHEECK_03860 1.3e-101 yesJ K Acetyltransferase (GNAT) family
JOLHEECK_03861 5.2e-104 cotJC P Spore Coat
JOLHEECK_03862 1.5e-45 cotJB S CotJB protein
JOLHEECK_03863 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
JOLHEECK_03864 5.5e-142 yesF GM NAD(P)H-binding
JOLHEECK_03865 2.5e-77 yesE S SnoaL-like domain
JOLHEECK_03866 8.5e-102 dhaR3 K Transcriptional regulator
JOLHEECK_03868 2.7e-126 yeeN K transcriptional regulatory protein
JOLHEECK_03870 1.6e-213 S Tetratricopeptide repeat
JOLHEECK_03871 1e-39
JOLHEECK_03872 4.1e-26 3.4.24.40 CO amine dehydrogenase activity
JOLHEECK_03873 2e-125 3.4.24.40 CO amine dehydrogenase activity
JOLHEECK_03874 8.7e-101 L endonuclease activity
JOLHEECK_03876 0.0 L nucleic acid phosphodiester bond hydrolysis
JOLHEECK_03877 4.2e-75 S Protein of unknown function, DUF600
JOLHEECK_03878 2.7e-27
JOLHEECK_03880 1.4e-100 S response regulator aspartate phosphatase
JOLHEECK_03882 5.8e-43
JOLHEECK_03884 0.0 L Type III restriction enzyme res subunit
JOLHEECK_03885 1.6e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JOLHEECK_03886 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JOLHEECK_03887 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JOLHEECK_03888 1.3e-148 yerO K Transcriptional regulator
JOLHEECK_03889 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JOLHEECK_03890 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JOLHEECK_03891 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JOLHEECK_03892 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOLHEECK_03893 6.1e-123 sapB S MgtC SapB transporter
JOLHEECK_03894 2.7e-196 yerI S homoserine kinase type II (protein kinase fold)
JOLHEECK_03895 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
JOLHEECK_03896 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JOLHEECK_03897 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JOLHEECK_03898 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JOLHEECK_03899 8.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
JOLHEECK_03900 4.8e-51 yerC S protein conserved in bacteria
JOLHEECK_03901 8.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
JOLHEECK_03902 0.0 yerA 3.5.4.2 F adenine deaminase
JOLHEECK_03903 2.7e-27 S Protein of unknown function (DUF2892)
JOLHEECK_03904 6.4e-227 yjeH E Amino acid permease
JOLHEECK_03905 3.5e-73 K helix_turn_helix ASNC type
JOLHEECK_03906 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
JOLHEECK_03907 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
JOLHEECK_03908 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JOLHEECK_03909 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JOLHEECK_03910 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JOLHEECK_03911 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JOLHEECK_03912 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JOLHEECK_03913 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JOLHEECK_03914 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
JOLHEECK_03915 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JOLHEECK_03916 4.5e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JOLHEECK_03917 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JOLHEECK_03918 8e-28 yebG S NETI protein
JOLHEECK_03919 8.9e-93 yebE S UPF0316 protein
JOLHEECK_03921 8.3e-116 yebC M Membrane
JOLHEECK_03922 7.8e-212 pbuG S permease
JOLHEECK_03923 9.8e-256 S Domain of unknown function (DUF4179)
JOLHEECK_03924 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
JOLHEECK_03925 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JOLHEECK_03926 0.0 yebA E COG1305 Transglutaminase-like enzymes
JOLHEECK_03927 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
JOLHEECK_03928 1.5e-175 yeaC S COG0714 MoxR-like ATPases
JOLHEECK_03929 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOLHEECK_03930 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
JOLHEECK_03931 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
JOLHEECK_03932 3.3e-175 yeaA S Protein of unknown function (DUF4003)
JOLHEECK_03933 8.4e-156 ydjP I Alpha/beta hydrolase family
JOLHEECK_03934 1.4e-34 ydjO S Cold-inducible protein YdjO
JOLHEECK_03936 2.3e-150 ydjN U Involved in the tonB-independent uptake of proteins
JOLHEECK_03937 4.5e-64 ydjM M Lytic transglycolase
JOLHEECK_03938 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
JOLHEECK_03939 2.7e-258 iolT EGP Major facilitator Superfamily
JOLHEECK_03940 4.7e-196 S Ion transport 2 domain protein
JOLHEECK_03941 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
JOLHEECK_03942 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
JOLHEECK_03943 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JOLHEECK_03944 5.1e-114 pspA KT Phage shock protein A
JOLHEECK_03945 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
JOLHEECK_03946 7.1e-256 gutA G MFS/sugar transport protein
JOLHEECK_03947 9.4e-200 gutB 1.1.1.14 E Dehydrogenase
JOLHEECK_03948 0.0 K NB-ARC domain
JOLHEECK_03949 1.1e-08 ydjC S Abhydrolase domain containing 18
JOLHEECK_03950 4.9e-257 J LlaJI restriction endonuclease
JOLHEECK_03951 1.2e-199 V AAA domain (dynein-related subfamily)
JOLHEECK_03953 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
JOLHEECK_03954 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
JOLHEECK_03955 6.4e-66 KL Phage plasmid primase P4 family
JOLHEECK_03957 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JOLHEECK_03958 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JOLHEECK_03959 7.9e-129 ydiL S CAAX protease self-immunity
JOLHEECK_03960 2.9e-27 ydiK S Domain of unknown function (DUF4305)
JOLHEECK_03961 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JOLHEECK_03962 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
JOLHEECK_03963 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JOLHEECK_03964 2.1e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
JOLHEECK_03965 0.0 ydiF S ABC transporter
JOLHEECK_03966 2e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JOLHEECK_03967 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
JOLHEECK_03968 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
JOLHEECK_03969 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
JOLHEECK_03970 1.3e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JOLHEECK_03972 7.8e-08
JOLHEECK_03973 7.9e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
JOLHEECK_03974 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
JOLHEECK_03975 1.2e-84 gerD
JOLHEECK_03976 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
JOLHEECK_03977 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOLHEECK_03978 9.7e-66 ybaK S Protein of unknown function (DUF2521)
JOLHEECK_03979 3.4e-143 ybaJ Q Methyltransferase domain
JOLHEECK_03980 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
JOLHEECK_03981 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JOLHEECK_03982 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JOLHEECK_03983 4e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOLHEECK_03984 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOLHEECK_03985 2.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOLHEECK_03986 3.6e-58 rplQ J Ribosomal protein L17
JOLHEECK_03987 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOLHEECK_03988 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JOLHEECK_03989 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JOLHEECK_03990 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JOLHEECK_03991 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JOLHEECK_03992 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
JOLHEECK_03993 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JOLHEECK_03994 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JOLHEECK_03995 1.8e-72 rplO J binds to the 23S rRNA
JOLHEECK_03996 1.9e-23 rpmD J Ribosomal protein L30
JOLHEECK_03997 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JOLHEECK_03998 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JOLHEECK_03999 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JOLHEECK_04000 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JOLHEECK_04001 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JOLHEECK_04002 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JOLHEECK_04003 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JOLHEECK_04004 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JOLHEECK_04005 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JOLHEECK_04006 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
JOLHEECK_04007 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JOLHEECK_04008 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JOLHEECK_04009 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JOLHEECK_04010 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JOLHEECK_04011 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JOLHEECK_04012 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JOLHEECK_04013 3e-105 rplD J Forms part of the polypeptide exit tunnel
JOLHEECK_04014 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JOLHEECK_04015 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
JOLHEECK_04016 2.2e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
JOLHEECK_04017 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JOLHEECK_04018 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JOLHEECK_04019 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JOLHEECK_04020 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JOLHEECK_04021 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
JOLHEECK_04022 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOLHEECK_04023 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOLHEECK_04024 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
JOLHEECK_04025 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JOLHEECK_04026 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JOLHEECK_04027 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JOLHEECK_04028 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JOLHEECK_04029 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
JOLHEECK_04030 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
JOLHEECK_04031 4.4e-115 sigH K Belongs to the sigma-70 factor family
JOLHEECK_04032 1.2e-88 yacP S RNA-binding protein containing a PIN domain
JOLHEECK_04033 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOLHEECK_04034 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JOLHEECK_04035 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JOLHEECK_04036 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
JOLHEECK_04037 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JOLHEECK_04038 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
JOLHEECK_04039 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
JOLHEECK_04040 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
JOLHEECK_04041 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JOLHEECK_04042 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JOLHEECK_04043 0.0 clpC O Belongs to the ClpA ClpB family
JOLHEECK_04044 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
JOLHEECK_04045 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
JOLHEECK_04046 2.9e-76 ctsR K Belongs to the CtsR family
JOLHEECK_04047 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
JOLHEECK_04048 7.9e-32 yaaL S Protein of unknown function (DUF2508)
JOLHEECK_04049 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JOLHEECK_04050 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JOLHEECK_04051 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JOLHEECK_04052 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JOLHEECK_04053 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
JOLHEECK_04054 5.6e-215 yaaH M Glycoside Hydrolase Family
JOLHEECK_04055 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
JOLHEECK_04056 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
JOLHEECK_04057 1.3e-09
JOLHEECK_04058 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JOLHEECK_04059 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JOLHEECK_04060 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JOLHEECK_04061 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JOLHEECK_04062 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
JOLHEECK_04063 1e-181 yaaC S YaaC-like Protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)