ORF_ID e_value Gene_name EC_number CAZy COGs Description
ADEHOEND_00001 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ADEHOEND_00002 9e-92 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ADEHOEND_00005 3.4e-39 S COG NOG14552 non supervised orthologous group
ADEHOEND_00010 2e-08
ADEHOEND_00017 2e-08
ADEHOEND_00024 7.8e-08
ADEHOEND_00032 2e-08
ADEHOEND_00036 2.7e-143 spo0M S COG4326 Sporulation control protein
ADEHOEND_00037 1.2e-26
ADEHOEND_00038 1.6e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
ADEHOEND_00039 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ADEHOEND_00040 1.9e-266 ygaK C Berberine and berberine like
ADEHOEND_00042 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
ADEHOEND_00043 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
ADEHOEND_00044 1.7e-171 ssuA M Sulfonate ABC transporter
ADEHOEND_00045 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
ADEHOEND_00046 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
ADEHOEND_00048 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ADEHOEND_00049 4.1e-78 ygaO
ADEHOEND_00050 4.8e-29 K Transcriptional regulator
ADEHOEND_00052 7.9e-114 yhzB S B3/4 domain
ADEHOEND_00053 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ADEHOEND_00054 4.4e-177 yhbB S Putative amidase domain
ADEHOEND_00055 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ADEHOEND_00056 1.2e-109 yhbD K Protein of unknown function (DUF4004)
ADEHOEND_00057 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
ADEHOEND_00058 8.5e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
ADEHOEND_00059 0.0 prkA T Ser protein kinase
ADEHOEND_00060 2.5e-225 yhbH S Belongs to the UPF0229 family
ADEHOEND_00061 2.2e-76 yhbI K DNA-binding transcription factor activity
ADEHOEND_00062 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
ADEHOEND_00063 3.1e-271 yhcA EGP Major facilitator Superfamily
ADEHOEND_00064 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
ADEHOEND_00065 2.8e-37 yhcC
ADEHOEND_00066 3.5e-55
ADEHOEND_00067 1.5e-59 yhcF K Transcriptional regulator
ADEHOEND_00068 4.4e-121 yhcG V ABC transporter, ATP-binding protein
ADEHOEND_00069 6.5e-165 yhcH V ABC transporter, ATP-binding protein
ADEHOEND_00070 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
ADEHOEND_00071 1e-30 cspB K Cold-shock protein
ADEHOEND_00072 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
ADEHOEND_00073 1.9e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
ADEHOEND_00074 4.1e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ADEHOEND_00075 1.1e-77 S Protein of unknown function (DUF2812)
ADEHOEND_00076 1.2e-49 K Transcriptional regulator PadR-like family
ADEHOEND_00077 2e-41 yhcM
ADEHOEND_00078 1.3e-67 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ADEHOEND_00079 2.5e-167 yhcP
ADEHOEND_00080 5.2e-100 yhcQ M Spore coat protein
ADEHOEND_00081 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
ADEHOEND_00082 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
ADEHOEND_00083 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ADEHOEND_00084 9.3e-68 yhcU S Family of unknown function (DUF5365)
ADEHOEND_00085 9.9e-68 yhcV S COG0517 FOG CBS domain
ADEHOEND_00086 4.6e-120 yhcW 5.4.2.6 S hydrolase
ADEHOEND_00087 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
ADEHOEND_00088 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADEHOEND_00089 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ADEHOEND_00090 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
ADEHOEND_00091 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ADEHOEND_00092 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ADEHOEND_00093 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
ADEHOEND_00094 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
ADEHOEND_00095 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ADEHOEND_00096 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
ADEHOEND_00097 1.2e-38 yhdB S YhdB-like protein
ADEHOEND_00098 4.8e-54 yhdC S Protein of unknown function (DUF3889)
ADEHOEND_00099 1.5e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
ADEHOEND_00100 1e-75 nsrR K Transcriptional regulator
ADEHOEND_00101 3.6e-237 ygxB M Conserved TM helix
ADEHOEND_00102 6.3e-276 ycgB S Stage V sporulation protein R
ADEHOEND_00103 5e-254 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
ADEHOEND_00104 1e-139 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
ADEHOEND_00105 3.8e-162 citR K Transcriptional regulator
ADEHOEND_00106 1.3e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
ADEHOEND_00107 2.7e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ADEHOEND_00108 3.4e-250 yhdG E amino acid
ADEHOEND_00109 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
ADEHOEND_00110 7.2e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ADEHOEND_00111 2e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ADEHOEND_00112 8.1e-45 yhdK S Sigma-M inhibitor protein
ADEHOEND_00113 1.5e-200 yhdL S Sigma factor regulator N-terminal
ADEHOEND_00114 1e-84 sigM K Belongs to the sigma-70 factor family. ECF subfamily
ADEHOEND_00115 1.7e-190 yhdN C Aldo keto reductase
ADEHOEND_00116 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
ADEHOEND_00117 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
ADEHOEND_00118 4.1e-74 cueR K transcriptional
ADEHOEND_00119 4.4e-222 yhdR 2.6.1.1 E Aminotransferase
ADEHOEND_00120 2.1e-239 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
ADEHOEND_00121 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADEHOEND_00122 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADEHOEND_00123 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
ADEHOEND_00125 1.6e-202 yhdY M Mechanosensitive ion channel
ADEHOEND_00126 4.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
ADEHOEND_00127 5.3e-137 yheN G deacetylase
ADEHOEND_00128 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
ADEHOEND_00129 3.7e-225 nhaC C Na H antiporter
ADEHOEND_00130 5.4e-82 nhaX T Belongs to the universal stress protein A family
ADEHOEND_00131 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
ADEHOEND_00132 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
ADEHOEND_00133 7.6e-109 yheG GM NAD(P)H-binding
ADEHOEND_00134 6.3e-28 sspB S spore protein
ADEHOEND_00135 1.3e-36 yheE S Family of unknown function (DUF5342)
ADEHOEND_00136 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
ADEHOEND_00137 4.3e-216 yheC HJ YheC/D like ATP-grasp
ADEHOEND_00138 1.8e-201 yheB S Belongs to the UPF0754 family
ADEHOEND_00139 9.5e-48 yheA S Belongs to the UPF0342 family
ADEHOEND_00140 3.1e-206 yhaZ L DNA alkylation repair enzyme
ADEHOEND_00141 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
ADEHOEND_00142 3.9e-292 hemZ H coproporphyrinogen III oxidase
ADEHOEND_00143 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
ADEHOEND_00144 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
ADEHOEND_00146 2.3e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
ADEHOEND_00147 1.1e-26 S YhzD-like protein
ADEHOEND_00148 1.2e-166 yhaQ S ABC transporter, ATP-binding protein
ADEHOEND_00149 1.6e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
ADEHOEND_00150 2.2e-224 yhaO L DNA repair exonuclease
ADEHOEND_00151 0.0 yhaN L AAA domain
ADEHOEND_00152 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
ADEHOEND_00153 1.6e-21 yhaL S Sporulation protein YhaL
ADEHOEND_00154 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ADEHOEND_00155 8.7e-90 yhaK S Putative zincin peptidase
ADEHOEND_00156 1.3e-54 yhaI S Protein of unknown function (DUF1878)
ADEHOEND_00157 1e-113 hpr K Negative regulator of protease production and sporulation
ADEHOEND_00158 7e-39 yhaH S YtxH-like protein
ADEHOEND_00159 3.6e-80 trpP S Tryptophan transporter TrpP
ADEHOEND_00160 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ADEHOEND_00161 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
ADEHOEND_00162 2.3e-136 ecsA V transporter (ATP-binding protein)
ADEHOEND_00163 1.8e-215 ecsB U ABC transporter
ADEHOEND_00164 1.4e-114 ecsC S EcsC protein family
ADEHOEND_00165 5.7e-230 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
ADEHOEND_00166 2.7e-231 yhfA C membrane
ADEHOEND_00167 7.9e-27 1.15.1.2 C Rubrerythrin
ADEHOEND_00168 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
ADEHOEND_00169 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ADEHOEND_00170 1.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ADEHOEND_00171 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
ADEHOEND_00172 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ADEHOEND_00173 5.4e-101 yhgD K Transcriptional regulator
ADEHOEND_00174 2.5e-237 yhgE S YhgE Pip N-terminal domain protein
ADEHOEND_00175 4.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADEHOEND_00176 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
ADEHOEND_00177 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
ADEHOEND_00178 1.7e-72 3.4.13.21 S ASCH
ADEHOEND_00179 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ADEHOEND_00180 2e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
ADEHOEND_00181 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
ADEHOEND_00182 1.9e-110 yhfK GM NmrA-like family
ADEHOEND_00183 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
ADEHOEND_00184 1.9e-65 yhfM
ADEHOEND_00185 3.5e-241 yhfN 3.4.24.84 O Peptidase M48
ADEHOEND_00186 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
ADEHOEND_00187 3.1e-75 VY92_01935 K acetyltransferase
ADEHOEND_00188 5.4e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
ADEHOEND_00189 4.3e-159 yfmC M Periplasmic binding protein
ADEHOEND_00190 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
ADEHOEND_00191 5.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
ADEHOEND_00192 6.4e-268 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
ADEHOEND_00193 6.5e-91 bioY S BioY family
ADEHOEND_00194 1.7e-182 hemAT NT chemotaxis protein
ADEHOEND_00195 4.7e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
ADEHOEND_00196 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ADEHOEND_00197 1.3e-32 yhzC S IDEAL
ADEHOEND_00198 4.2e-109 comK K Competence transcription factor
ADEHOEND_00199 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
ADEHOEND_00200 7.8e-42 yhjA S Excalibur calcium-binding domain
ADEHOEND_00201 1.3e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADEHOEND_00202 6.9e-27 yhjC S Protein of unknown function (DUF3311)
ADEHOEND_00203 6.7e-60 yhjD
ADEHOEND_00204 3.4e-109 yhjE S SNARE associated Golgi protein
ADEHOEND_00205 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
ADEHOEND_00206 2.4e-278 yhjG CH FAD binding domain
ADEHOEND_00207 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
ADEHOEND_00208 4.5e-214 glcP G Major Facilitator Superfamily
ADEHOEND_00209 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
ADEHOEND_00210 4.5e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
ADEHOEND_00211 7.7e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
ADEHOEND_00212 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
ADEHOEND_00213 5.1e-199 abrB S membrane
ADEHOEND_00214 7.9e-211 EGP Transmembrane secretion effector
ADEHOEND_00215 0.0 S Sugar transport-related sRNA regulator N-term
ADEHOEND_00216 1.1e-77 yhjR S Rubrerythrin
ADEHOEND_00217 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
ADEHOEND_00218 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
ADEHOEND_00219 6.9e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
ADEHOEND_00220 0.0 sbcC L COG0419 ATPase involved in DNA repair
ADEHOEND_00221 1.1e-49 yisB V COG1403 Restriction endonuclease
ADEHOEND_00222 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
ADEHOEND_00223 3e-66 gerPE S Spore germination protein GerPE
ADEHOEND_00224 6.3e-24 gerPD S Spore germination protein
ADEHOEND_00225 1.8e-54 gerPC S Spore germination protein
ADEHOEND_00226 4e-34 gerPB S cell differentiation
ADEHOEND_00227 1.9e-33 gerPA S Spore germination protein
ADEHOEND_00228 1.5e-22 yisI S Spo0E like sporulation regulatory protein
ADEHOEND_00229 1.1e-172 cotH M Spore Coat
ADEHOEND_00230 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
ADEHOEND_00231 3.9e-57 yisL S UPF0344 protein
ADEHOEND_00232 0.0 wprA O Belongs to the peptidase S8 family
ADEHOEND_00233 2.1e-102 yisN S Protein of unknown function (DUF2777)
ADEHOEND_00234 0.0 asnO 6.3.5.4 E Asparagine synthase
ADEHOEND_00235 3.9e-87 yizA S Damage-inducible protein DinB
ADEHOEND_00236 2.8e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
ADEHOEND_00237 1.5e-242 yisQ V Mate efflux family protein
ADEHOEND_00238 1.2e-160 yisR K Transcriptional regulator
ADEHOEND_00239 1.5e-183 purR K helix_turn _helix lactose operon repressor
ADEHOEND_00240 1.5e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
ADEHOEND_00241 7e-92 yisT S DinB family
ADEHOEND_00242 1.9e-107 argO S Lysine exporter protein LysE YggA
ADEHOEND_00243 1.8e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ADEHOEND_00244 4e-36 mcbG S Pentapeptide repeats (9 copies)
ADEHOEND_00245 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
ADEHOEND_00246 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
ADEHOEND_00247 2.5e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
ADEHOEND_00248 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
ADEHOEND_00249 5.3e-119 comB 3.1.3.71 H Belongs to the ComB family
ADEHOEND_00250 5.4e-141 yitD 4.4.1.19 S synthase
ADEHOEND_00251 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ADEHOEND_00252 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
ADEHOEND_00253 1.5e-228 yitG EGP Major facilitator Superfamily
ADEHOEND_00254 2e-160 yitH K Acetyltransferase (GNAT) domain
ADEHOEND_00255 7.8e-79 yjcF S Acetyltransferase (GNAT) domain
ADEHOEND_00256 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
ADEHOEND_00257 5.6e-54 yajQ S Belongs to the UPF0234 family
ADEHOEND_00258 6.9e-161 cvfB S protein conserved in bacteria
ADEHOEND_00259 8.5e-94
ADEHOEND_00260 1.4e-170
ADEHOEND_00261 1.5e-97 S Sporulation delaying protein SdpA
ADEHOEND_00262 1.5e-58 K Transcriptional regulator PadR-like family
ADEHOEND_00263 2e-95
ADEHOEND_00264 1.4e-44 yitR S Domain of unknown function (DUF3784)
ADEHOEND_00265 1.6e-307 nprB 3.4.24.28 E Peptidase M4
ADEHOEND_00266 8.4e-159 yitS S protein conserved in bacteria
ADEHOEND_00267 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
ADEHOEND_00268 5e-73 ipi S Intracellular proteinase inhibitor
ADEHOEND_00269 1.2e-17 S Protein of unknown function (DUF3813)
ADEHOEND_00270 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
ADEHOEND_00271 1e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
ADEHOEND_00272 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
ADEHOEND_00273 1.5e-22 pilT S Proteolipid membrane potential modulator
ADEHOEND_00274 6e-266 yitY C D-arabinono-1,4-lactone oxidase
ADEHOEND_00275 1.7e-88 norB G Major Facilitator Superfamily
ADEHOEND_00276 1.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ADEHOEND_00277 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ADEHOEND_00278 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
ADEHOEND_00279 6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
ADEHOEND_00280 9.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ADEHOEND_00281 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
ADEHOEND_00282 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADEHOEND_00283 9.5e-28 yjzC S YjzC-like protein
ADEHOEND_00284 2.3e-16 yjzD S Protein of unknown function (DUF2929)
ADEHOEND_00285 6.8e-141 yjaU I carboxylic ester hydrolase activity
ADEHOEND_00286 1.8e-101 yjaV
ADEHOEND_00287 1.1e-183 med S Transcriptional activator protein med
ADEHOEND_00288 4.7e-25 comZ S ComZ
ADEHOEND_00289 2.7e-22 yjzB
ADEHOEND_00290 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADEHOEND_00291 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ADEHOEND_00292 7.8e-151 yjaZ O Zn-dependent protease
ADEHOEND_00293 1.8e-184 appD P Belongs to the ABC transporter superfamily
ADEHOEND_00294 6.5e-187 appF E Belongs to the ABC transporter superfamily
ADEHOEND_00295 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
ADEHOEND_00296 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADEHOEND_00297 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADEHOEND_00298 6.5e-147 yjbA S Belongs to the UPF0736 family
ADEHOEND_00299 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
ADEHOEND_00300 0.0 oppA E ABC transporter substrate-binding protein
ADEHOEND_00301 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADEHOEND_00302 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADEHOEND_00303 1.5e-197 oppD P Belongs to the ABC transporter superfamily
ADEHOEND_00304 5.5e-172 oppF E Belongs to the ABC transporter superfamily
ADEHOEND_00305 1.8e-210 yjbB EGP Major Facilitator Superfamily
ADEHOEND_00306 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ADEHOEND_00307 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ADEHOEND_00308 6e-112 yjbE P Integral membrane protein TerC family
ADEHOEND_00309 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
ADEHOEND_00310 2.1e-221 yjbF S Competence protein
ADEHOEND_00311 0.0 pepF E oligoendopeptidase F
ADEHOEND_00312 1.8e-20
ADEHOEND_00314 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
ADEHOEND_00315 1.1e-71 yjbI S Bacterial-like globin
ADEHOEND_00316 3.8e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
ADEHOEND_00317 1e-99 yjbK S protein conserved in bacteria
ADEHOEND_00318 1.6e-61 yjbL S Belongs to the UPF0738 family
ADEHOEND_00319 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
ADEHOEND_00320 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ADEHOEND_00321 2.3e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ADEHOEND_00322 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
ADEHOEND_00323 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ADEHOEND_00324 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ADEHOEND_00325 9.3e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
ADEHOEND_00326 1.2e-213 thiO 1.4.3.19 E Glycine oxidase
ADEHOEND_00327 2.6e-29 thiS H thiamine diphosphate biosynthetic process
ADEHOEND_00328 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
ADEHOEND_00329 5.1e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
ADEHOEND_00330 2.2e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ADEHOEND_00331 9.5e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
ADEHOEND_00332 5.9e-54 yjbX S Spore coat protein
ADEHOEND_00333 4.4e-82 cotZ S Spore coat protein
ADEHOEND_00334 7.6e-96 cotY S Spore coat protein Z
ADEHOEND_00335 1.6e-72 cotX S Spore Coat Protein X and V domain
ADEHOEND_00336 8.8e-24 cotW
ADEHOEND_00337 1.1e-54 cotV S Spore Coat Protein X and V domain
ADEHOEND_00338 4.3e-56 yjcA S Protein of unknown function (DUF1360)
ADEHOEND_00341 2.9e-38 spoVIF S Stage VI sporulation protein F
ADEHOEND_00342 0.0 yjcD 3.6.4.12 L DNA helicase
ADEHOEND_00343 1.7e-38
ADEHOEND_00344 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ADEHOEND_00345 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
ADEHOEND_00346 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
ADEHOEND_00347 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
ADEHOEND_00348 4.2e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
ADEHOEND_00349 7.7e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
ADEHOEND_00350 5.4e-212 yjcL S Protein of unknown function (DUF819)
ADEHOEND_00353 7.8e-190 S Putative amidase domain
ADEHOEND_00354 2.6e-44 yjcN
ADEHOEND_00357 8.5e-81 L Transposase
ADEHOEND_00358 1.6e-72 yjcP
ADEHOEND_00359 4.1e-49 S YjcQ protein
ADEHOEND_00360 1.1e-92 yqaS L DNA packaging
ADEHOEND_00361 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
ADEHOEND_00362 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
ADEHOEND_00364 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
ADEHOEND_00365 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
ADEHOEND_00366 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
ADEHOEND_00367 4.5e-49 yjdF S Protein of unknown function (DUF2992)
ADEHOEND_00368 4.5e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
ADEHOEND_00370 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ADEHOEND_00371 4.2e-29 S Domain of unknown function (DUF4177)
ADEHOEND_00372 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
ADEHOEND_00373 1.4e-173 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
ADEHOEND_00375 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
ADEHOEND_00376 1.4e-81 S Protein of unknown function (DUF2690)
ADEHOEND_00377 8.9e-20 yjfB S Putative motility protein
ADEHOEND_00378 5.6e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
ADEHOEND_00379 1.2e-45 T PhoQ Sensor
ADEHOEND_00380 8.9e-104 yjgB S Domain of unknown function (DUF4309)
ADEHOEND_00381 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
ADEHOEND_00382 4.3e-95 yjgD S Protein of unknown function (DUF1641)
ADEHOEND_00383 8.7e-07 S Domain of unknown function (DUF4352)
ADEHOEND_00384 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
ADEHOEND_00386 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
ADEHOEND_00387 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
ADEHOEND_00388 8.2e-30
ADEHOEND_00389 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
ADEHOEND_00390 1.9e-122 ybbM S transport system, permease component
ADEHOEND_00391 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
ADEHOEND_00392 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
ADEHOEND_00393 2.8e-93 yjlB S Cupin domain
ADEHOEND_00394 7.1e-66 yjlC S Protein of unknown function (DUF1641)
ADEHOEND_00395 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
ADEHOEND_00396 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
ADEHOEND_00397 5.8e-250 yjmB G symporter YjmB
ADEHOEND_00398 4.3e-194 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
ADEHOEND_00399 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
ADEHOEND_00400 2.3e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
ADEHOEND_00401 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ADEHOEND_00402 3.7e-227 exuT G Sugar (and other) transporter
ADEHOEND_00403 2.3e-184 exuR K transcriptional
ADEHOEND_00404 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
ADEHOEND_00405 4.6e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
ADEHOEND_00406 7.4e-130 MA20_18170 S membrane transporter protein
ADEHOEND_00407 2.3e-78 yjoA S DinB family
ADEHOEND_00408 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
ADEHOEND_00409 1e-212 S response regulator aspartate phosphatase
ADEHOEND_00411 5.2e-37 S YCII-related domain
ADEHOEND_00412 6.8e-165 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
ADEHOEND_00413 1.8e-60 yjqA S Bacterial PH domain
ADEHOEND_00414 2.1e-111 yjqB S Pfam:DUF867
ADEHOEND_00415 9.8e-160 ydbD P Catalase
ADEHOEND_00416 4.3e-109 xkdA E IrrE N-terminal-like domain
ADEHOEND_00417 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
ADEHOEND_00419 5e-156 xkdB K sequence-specific DNA binding
ADEHOEND_00420 9.2e-118 xkdC L Bacterial dnaA protein
ADEHOEND_00423 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
ADEHOEND_00424 2.2e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
ADEHOEND_00425 5.3e-139 xtmA L phage terminase small subunit
ADEHOEND_00426 1.4e-253 xtmB S phage terminase, large subunit
ADEHOEND_00427 6e-285 yqbA S portal protein
ADEHOEND_00428 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
ADEHOEND_00429 1.3e-168 xkdG S Phage capsid family
ADEHOEND_00430 5.5e-65 yqbG S Protein of unknown function (DUF3199)
ADEHOEND_00431 8.7e-65 yqbH S Domain of unknown function (DUF3599)
ADEHOEND_00432 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
ADEHOEND_00433 1.9e-77 xkdJ
ADEHOEND_00434 2.5e-256 xkdK S Phage tail sheath C-terminal domain
ADEHOEND_00435 6.1e-76 xkdM S Phage tail tube protein
ADEHOEND_00436 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
ADEHOEND_00437 0.0 xkdO L Transglycosylase SLT domain
ADEHOEND_00438 4.1e-121 xkdP S Lysin motif
ADEHOEND_00439 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
ADEHOEND_00440 2.1e-39 xkdR S Protein of unknown function (DUF2577)
ADEHOEND_00441 3.1e-69 xkdS S Protein of unknown function (DUF2634)
ADEHOEND_00442 6.7e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
ADEHOEND_00443 1.2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
ADEHOEND_00444 1.5e-40
ADEHOEND_00445 1e-261
ADEHOEND_00446 5.4e-53 xkdW S XkdW protein
ADEHOEND_00447 5.5e-22 xkdX
ADEHOEND_00448 1.7e-151 xepA
ADEHOEND_00449 6.2e-39 xhlA S Haemolysin XhlA
ADEHOEND_00450 9.3e-40 xhlB S SPP1 phage holin
ADEHOEND_00451 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ADEHOEND_00452 6.7e-23 spoIISB S Stage II sporulation protein SB
ADEHOEND_00453 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
ADEHOEND_00454 5.8e-175 pit P phosphate transporter
ADEHOEND_00455 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
ADEHOEND_00456 4e-240 steT E amino acid
ADEHOEND_00457 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
ADEHOEND_00458 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ADEHOEND_00459 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
ADEHOEND_00461 7.5e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADEHOEND_00462 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
ADEHOEND_00463 2.5e-152 dppA E D-aminopeptidase
ADEHOEND_00464 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADEHOEND_00465 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADEHOEND_00466 1.3e-187 dppD P Belongs to the ABC transporter superfamily
ADEHOEND_00467 0.0 dppE E ABC transporter substrate-binding protein
ADEHOEND_00469 1.3e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
ADEHOEND_00470 2.3e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
ADEHOEND_00471 2.7e-163 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
ADEHOEND_00472 9.4e-186 ykfD E Belongs to the ABC transporter superfamily
ADEHOEND_00473 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
ADEHOEND_00474 2e-160 ykgA E Amidinotransferase
ADEHOEND_00475 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
ADEHOEND_00476 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADEHOEND_00477 5.5e-09
ADEHOEND_00478 7.8e-129 ykjA S Protein of unknown function (DUF421)
ADEHOEND_00479 4.8e-96 ykkA S Protein of unknown function (DUF664)
ADEHOEND_00480 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
ADEHOEND_00481 3.5e-55 ykkC P Multidrug resistance protein
ADEHOEND_00482 7e-50 ykkD P Multidrug resistance protein
ADEHOEND_00483 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
ADEHOEND_00484 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ADEHOEND_00485 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ADEHOEND_00486 1.3e-70 ohrA O Organic hydroperoxide resistance protein
ADEHOEND_00487 4.8e-73 ohrR K COG1846 Transcriptional regulators
ADEHOEND_00488 2.4e-71 ohrB O Organic hydroperoxide resistance protein
ADEHOEND_00490 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
ADEHOEND_00491 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ADEHOEND_00492 1.6e-174 isp O Belongs to the peptidase S8 family
ADEHOEND_00493 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ADEHOEND_00494 5.3e-136 ykoC P Cobalt transport protein
ADEHOEND_00495 5.7e-264 P ABC transporter, ATP-binding protein
ADEHOEND_00496 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
ADEHOEND_00497 1.6e-108 ykoF S YKOF-related Family
ADEHOEND_00498 7.9e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ADEHOEND_00499 1.4e-240 ykoH 2.7.13.3 T Histidine kinase
ADEHOEND_00500 9.9e-110 ykoI S Peptidase propeptide and YPEB domain
ADEHOEND_00501 8.3e-85 ykoJ S Peptidase propeptide and YPEB domain
ADEHOEND_00504 2.2e-222 mgtE P Acts as a magnesium transporter
ADEHOEND_00505 1.4e-53 tnrA K transcriptional
ADEHOEND_00506 5.9e-18
ADEHOEND_00507 6.9e-26 ykoL
ADEHOEND_00508 1.3e-81 mhqR K transcriptional
ADEHOEND_00509 3.1e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
ADEHOEND_00510 1.4e-98 ykoP G polysaccharide deacetylase
ADEHOEND_00511 3.5e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
ADEHOEND_00512 0.0 ykoS
ADEHOEND_00513 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
ADEHOEND_00514 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
ADEHOEND_00515 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ADEHOEND_00516 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
ADEHOEND_00517 3.5e-109 ykoX S membrane-associated protein
ADEHOEND_00518 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
ADEHOEND_00519 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADEHOEND_00520 9.1e-116 rsgI S Anti-sigma factor N-terminus
ADEHOEND_00521 1.9e-26 sspD S small acid-soluble spore protein
ADEHOEND_00522 1.5e-124 ykrK S Domain of unknown function (DUF1836)
ADEHOEND_00523 3.5e-155 htpX O Belongs to the peptidase M48B family
ADEHOEND_00524 1.1e-232 ktrB P COG0168 Trk-type K transport systems, membrane components
ADEHOEND_00525 1.2e-10 ydfR S Protein of unknown function (DUF421)
ADEHOEND_00526 4.1e-18 ykzE
ADEHOEND_00527 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
ADEHOEND_00528 0.0 kinE 2.7.13.3 T Histidine kinase
ADEHOEND_00529 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADEHOEND_00531 1.4e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ADEHOEND_00532 2.4e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ADEHOEND_00533 1e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
ADEHOEND_00534 1.5e-230 mtnE 2.6.1.83 E Aminotransferase
ADEHOEND_00535 1.4e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
ADEHOEND_00536 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ADEHOEND_00537 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
ADEHOEND_00538 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ADEHOEND_00539 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
ADEHOEND_00540 6.4e-09 S Spo0E like sporulation regulatory protein
ADEHOEND_00541 1.8e-64 eag
ADEHOEND_00542 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
ADEHOEND_00543 1.3e-75 ykvE K transcriptional
ADEHOEND_00544 2.5e-125 motB N Flagellar motor protein
ADEHOEND_00545 1e-137 motA N flagellar motor
ADEHOEND_00546 0.0 clpE O Belongs to the ClpA ClpB family
ADEHOEND_00547 2.6e-178 ykvI S membrane
ADEHOEND_00548 9.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ADEHOEND_00549 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
ADEHOEND_00550 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
ADEHOEND_00551 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ADEHOEND_00552 2e-61 ykvN K Transcriptional regulator
ADEHOEND_00553 2.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
ADEHOEND_00554 9.9e-216 ykvP 3.5.1.28 M Glycosyl transferases group 1
ADEHOEND_00555 3.5e-35 3.5.1.104 M LysM domain
ADEHOEND_00556 6.9e-162 G Glycosyl hydrolases family 18
ADEHOEND_00557 5.6e-46 ykvR S Protein of unknown function (DUF3219)
ADEHOEND_00558 6e-25 ykvS S protein conserved in bacteria
ADEHOEND_00559 2.8e-28
ADEHOEND_00560 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
ADEHOEND_00561 3.8e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ADEHOEND_00562 1.6e-88 stoA CO thiol-disulfide
ADEHOEND_00563 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
ADEHOEND_00564 2.3e-09
ADEHOEND_00565 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
ADEHOEND_00566 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
ADEHOEND_00568 2.2e-127 glcT K antiterminator
ADEHOEND_00569 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ADEHOEND_00570 2.1e-39 ptsH G phosphocarrier protein HPr
ADEHOEND_00571 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADEHOEND_00572 7.2e-39 splA S Transcriptional regulator
ADEHOEND_00573 7.5e-202 splB 4.1.99.14 L Spore photoproduct lyase
ADEHOEND_00574 4.9e-128 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ADEHOEND_00575 1.6e-261 mcpC NT chemotaxis protein
ADEHOEND_00576 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
ADEHOEND_00577 8e-124 ykwD J protein with SCP PR1 domains
ADEHOEND_00578 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
ADEHOEND_00579 0.0 pilS 2.7.13.3 T Histidine kinase
ADEHOEND_00580 8e-224 patA 2.6.1.1 E Aminotransferase
ADEHOEND_00581 2.2e-15
ADEHOEND_00582 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
ADEHOEND_00583 1.7e-84 ykyB S YkyB-like protein
ADEHOEND_00584 1.7e-235 ykuC EGP Major facilitator Superfamily
ADEHOEND_00585 1.5e-86 ykuD S protein conserved in bacteria
ADEHOEND_00586 1.6e-165 ykuE S Metallophosphoesterase
ADEHOEND_00587 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ADEHOEND_00588 5.2e-234 ykuI T Diguanylate phosphodiesterase
ADEHOEND_00589 3.9e-37 ykuJ S protein conserved in bacteria
ADEHOEND_00590 4.4e-94 ykuK S Ribonuclease H-like
ADEHOEND_00591 3.9e-27 ykzF S Antirepressor AbbA
ADEHOEND_00592 1.6e-76 ykuL S CBS domain
ADEHOEND_00593 3.5e-168 ccpC K Transcriptional regulator
ADEHOEND_00594 8.5e-84 fld C Flavodoxin domain
ADEHOEND_00595 3e-175 ykuO
ADEHOEND_00596 3.9e-78 fld C Flavodoxin
ADEHOEND_00597 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
ADEHOEND_00598 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
ADEHOEND_00599 9e-37 ykuS S Belongs to the UPF0180 family
ADEHOEND_00600 8.8e-142 ykuT M Mechanosensitive ion channel
ADEHOEND_00601 3.9e-101 ykuU O Alkyl hydroperoxide reductase
ADEHOEND_00602 7e-80 ykuV CO thiol-disulfide
ADEHOEND_00603 5.8e-95 rok K Repressor of ComK
ADEHOEND_00604 4.2e-146 yknT
ADEHOEND_00605 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
ADEHOEND_00606 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
ADEHOEND_00607 8.1e-246 moeA 2.10.1.1 H molybdopterin
ADEHOEND_00608 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
ADEHOEND_00609 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
ADEHOEND_00610 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ADEHOEND_00611 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
ADEHOEND_00612 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
ADEHOEND_00613 1e-117 yknW S Yip1 domain
ADEHOEND_00614 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADEHOEND_00615 2.5e-124 macB V ABC transporter, ATP-binding protein
ADEHOEND_00616 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
ADEHOEND_00617 3.1e-136 fruR K Transcriptional regulator
ADEHOEND_00618 3.1e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
ADEHOEND_00619 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
ADEHOEND_00620 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
ADEHOEND_00621 8.1e-39 ykoA
ADEHOEND_00622 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
ADEHOEND_00623 1.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ADEHOEND_00624 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
ADEHOEND_00625 1.1e-12 S Uncharacterized protein YkpC
ADEHOEND_00626 7.7e-183 mreB D Rod-share determining protein MreBH
ADEHOEND_00627 1.5e-43 abrB K of stationary sporulation gene expression
ADEHOEND_00628 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
ADEHOEND_00629 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
ADEHOEND_00630 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
ADEHOEND_00631 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ADEHOEND_00632 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ADEHOEND_00633 8.2e-31 ykzG S Belongs to the UPF0356 family
ADEHOEND_00634 1.4e-147 ykrA S hydrolases of the HAD superfamily
ADEHOEND_00635 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ADEHOEND_00637 2e-115 recN L Putative cell-wall binding lipoprotein
ADEHOEND_00638 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
ADEHOEND_00639 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
ADEHOEND_00640 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ADEHOEND_00641 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
ADEHOEND_00642 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
ADEHOEND_00643 3.5e-277 speA 4.1.1.19 E Arginine
ADEHOEND_00644 1.6e-42 yktA S Belongs to the UPF0223 family
ADEHOEND_00645 4.6e-117 yktB S Belongs to the UPF0637 family
ADEHOEND_00646 7.1e-26 ykzI
ADEHOEND_00647 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
ADEHOEND_00648 2.2e-76 ykzC S Acetyltransferase (GNAT) family
ADEHOEND_00649 8.7e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ADEHOEND_00650 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
ADEHOEND_00651 0.0 ylaA
ADEHOEND_00652 2.7e-42 ylaB
ADEHOEND_00653 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
ADEHOEND_00654 7.1e-12 sigC S Putative zinc-finger
ADEHOEND_00655 4.1e-38 ylaE
ADEHOEND_00656 8.2e-22 S Family of unknown function (DUF5325)
ADEHOEND_00657 0.0 typA T GTP-binding protein TypA
ADEHOEND_00658 4.2e-47 ylaH S YlaH-like protein
ADEHOEND_00659 2.5e-32 ylaI S protein conserved in bacteria
ADEHOEND_00660 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ADEHOEND_00661 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
ADEHOEND_00662 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ADEHOEND_00663 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
ADEHOEND_00664 8.7e-44 ylaN S Belongs to the UPF0358 family
ADEHOEND_00665 4.5e-214 ftsW D Belongs to the SEDS family
ADEHOEND_00666 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ADEHOEND_00667 7.7e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
ADEHOEND_00668 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
ADEHOEND_00669 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
ADEHOEND_00670 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ADEHOEND_00671 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
ADEHOEND_00672 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
ADEHOEND_00673 3.4e-166 ctaG S cytochrome c oxidase
ADEHOEND_00674 7e-62 ylbA S YugN-like family
ADEHOEND_00675 2.6e-74 ylbB T COG0517 FOG CBS domain
ADEHOEND_00676 9.6e-200 ylbC S protein with SCP PR1 domains
ADEHOEND_00677 4.1e-63 ylbD S Putative coat protein
ADEHOEND_00678 2.5e-36 ylbE S YlbE-like protein
ADEHOEND_00679 1.8e-75 ylbF S Belongs to the UPF0342 family
ADEHOEND_00680 3.7e-38 ylbG S UPF0298 protein
ADEHOEND_00681 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
ADEHOEND_00682 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ADEHOEND_00683 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
ADEHOEND_00684 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
ADEHOEND_00685 6.8e-187 ylbL T Belongs to the peptidase S16 family
ADEHOEND_00686 4e-234 ylbM S Belongs to the UPF0348 family
ADEHOEND_00688 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
ADEHOEND_00689 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
ADEHOEND_00690 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
ADEHOEND_00691 1.5e-88 ylbP K n-acetyltransferase
ADEHOEND_00692 6.1e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ADEHOEND_00693 3.2e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ADEHOEND_00694 2.9e-78 mraZ K Belongs to the MraZ family
ADEHOEND_00695 4.7e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ADEHOEND_00696 3.7e-44 ftsL D Essential cell division protein
ADEHOEND_00697 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
ADEHOEND_00698 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
ADEHOEND_00699 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADEHOEND_00700 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADEHOEND_00701 1.9e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ADEHOEND_00702 5.7e-186 spoVE D Belongs to the SEDS family
ADEHOEND_00703 6.7e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ADEHOEND_00704 5.3e-167 murB 1.3.1.98 M cell wall formation
ADEHOEND_00705 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ADEHOEND_00706 4.1e-103 ylxW S protein conserved in bacteria
ADEHOEND_00707 2.6e-90 ylxX S protein conserved in bacteria
ADEHOEND_00708 2.8e-55 sbp S small basic protein
ADEHOEND_00709 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ADEHOEND_00710 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADEHOEND_00711 0.0 bpr O COG1404 Subtilisin-like serine proteases
ADEHOEND_00712 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
ADEHOEND_00713 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADEHOEND_00714 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADEHOEND_00715 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
ADEHOEND_00716 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
ADEHOEND_00717 2.4e-37 ylmC S sporulation protein
ADEHOEND_00718 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
ADEHOEND_00719 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ADEHOEND_00720 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ADEHOEND_00721 1.6e-39 yggT S membrane
ADEHOEND_00722 8.2e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
ADEHOEND_00723 2.6e-67 divIVA D Cell division initiation protein
ADEHOEND_00724 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ADEHOEND_00725 1.3e-63 dksA T COG1734 DnaK suppressor protein
ADEHOEND_00726 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ADEHOEND_00727 3.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ADEHOEND_00728 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ADEHOEND_00729 2.6e-231 pyrP F Xanthine uracil
ADEHOEND_00730 8.5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
ADEHOEND_00731 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ADEHOEND_00732 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ADEHOEND_00733 0.0 carB 6.3.5.5 F Belongs to the CarB family
ADEHOEND_00734 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
ADEHOEND_00735 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ADEHOEND_00736 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ADEHOEND_00737 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ADEHOEND_00739 1.7e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
ADEHOEND_00740 1.2e-178 cysP P phosphate transporter
ADEHOEND_00741 1.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
ADEHOEND_00742 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
ADEHOEND_00743 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
ADEHOEND_00744 2.2e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
ADEHOEND_00745 6.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
ADEHOEND_00746 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
ADEHOEND_00747 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
ADEHOEND_00748 3.1e-156 yloC S stress-induced protein
ADEHOEND_00749 1.5e-40 ylzA S Belongs to the UPF0296 family
ADEHOEND_00750 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
ADEHOEND_00751 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ADEHOEND_00752 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ADEHOEND_00753 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ADEHOEND_00754 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ADEHOEND_00755 5.2e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ADEHOEND_00756 5.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADEHOEND_00757 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ADEHOEND_00758 1.6e-140 stp 3.1.3.16 T phosphatase
ADEHOEND_00759 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
ADEHOEND_00760 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ADEHOEND_00761 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
ADEHOEND_00762 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
ADEHOEND_00763 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
ADEHOEND_00764 5.5e-59 asp S protein conserved in bacteria
ADEHOEND_00765 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
ADEHOEND_00766 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
ADEHOEND_00767 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
ADEHOEND_00768 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ADEHOEND_00769 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
ADEHOEND_00770 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ADEHOEND_00771 2.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
ADEHOEND_00772 1.1e-127 IQ reductase
ADEHOEND_00773 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ADEHOEND_00774 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ADEHOEND_00775 0.0 smc D Required for chromosome condensation and partitioning
ADEHOEND_00776 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ADEHOEND_00777 3.5e-85
ADEHOEND_00778 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ADEHOEND_00779 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ADEHOEND_00780 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
ADEHOEND_00781 4.5e-36 ylqC S Belongs to the UPF0109 family
ADEHOEND_00782 6.3e-61 ylqD S YlqD protein
ADEHOEND_00783 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ADEHOEND_00784 7.8e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
ADEHOEND_00785 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ADEHOEND_00786 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ADEHOEND_00787 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ADEHOEND_00788 4.3e-287 ylqG
ADEHOEND_00789 6.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
ADEHOEND_00790 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
ADEHOEND_00791 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ADEHOEND_00792 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
ADEHOEND_00793 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADEHOEND_00794 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ADEHOEND_00795 2.5e-169 xerC L tyrosine recombinase XerC
ADEHOEND_00796 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ADEHOEND_00797 4.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ADEHOEND_00798 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ADEHOEND_00799 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
ADEHOEND_00800 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
ADEHOEND_00801 1.9e-31 fliE N Flagellar hook-basal body
ADEHOEND_00802 1.6e-254 fliF N The M ring may be actively involved in energy transduction
ADEHOEND_00803 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
ADEHOEND_00804 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
ADEHOEND_00805 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
ADEHOEND_00806 1.5e-69 fliJ N Flagellar biosynthesis chaperone
ADEHOEND_00807 2.2e-36 ylxF S MgtE intracellular N domain
ADEHOEND_00808 5.1e-220 fliK N Flagellar hook-length control protein
ADEHOEND_00809 2.3e-72 flgD N Flagellar basal body rod modification protein
ADEHOEND_00810 8.2e-140 flgG N Flagellar basal body rod
ADEHOEND_00811 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
ADEHOEND_00812 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
ADEHOEND_00813 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADEHOEND_00814 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
ADEHOEND_00815 2.7e-96 fliZ N Flagellar biosynthesis protein, FliO
ADEHOEND_00816 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
ADEHOEND_00817 2.2e-36 fliQ N Role in flagellar biosynthesis
ADEHOEND_00818 3.6e-132 fliR N Flagellar biosynthetic protein FliR
ADEHOEND_00819 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ADEHOEND_00820 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ADEHOEND_00821 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
ADEHOEND_00822 4.1e-156 flhG D Belongs to the ParA family
ADEHOEND_00823 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
ADEHOEND_00824 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
ADEHOEND_00825 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
ADEHOEND_00826 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
ADEHOEND_00827 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
ADEHOEND_00828 9.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADEHOEND_00829 3.1e-76 ylxL
ADEHOEND_00830 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
ADEHOEND_00831 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ADEHOEND_00832 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
ADEHOEND_00833 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ADEHOEND_00834 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ADEHOEND_00835 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
ADEHOEND_00836 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
ADEHOEND_00837 7.7e-233 rasP M zinc metalloprotease
ADEHOEND_00838 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ADEHOEND_00839 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADEHOEND_00840 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
ADEHOEND_00841 1.1e-203 nusA K Participates in both transcription termination and antitermination
ADEHOEND_00842 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
ADEHOEND_00843 3.1e-47 ylxQ J ribosomal protein
ADEHOEND_00844 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ADEHOEND_00845 3e-44 ylxP S protein conserved in bacteria
ADEHOEND_00846 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ADEHOEND_00847 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ADEHOEND_00848 1.1e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
ADEHOEND_00849 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ADEHOEND_00850 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
ADEHOEND_00851 6.1e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
ADEHOEND_00852 4.4e-233 pepR S Belongs to the peptidase M16 family
ADEHOEND_00853 2.6e-42 ymxH S YlmC YmxH family
ADEHOEND_00854 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
ADEHOEND_00855 6.3e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
ADEHOEND_00856 1.6e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ADEHOEND_00857 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
ADEHOEND_00858 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADEHOEND_00859 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ADEHOEND_00860 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
ADEHOEND_00861 4.4e-32 S YlzJ-like protein
ADEHOEND_00862 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
ADEHOEND_00863 1.4e-133 ymfC K Transcriptional regulator
ADEHOEND_00864 3.8e-205 ymfD EGP Major facilitator Superfamily
ADEHOEND_00865 2e-233 ymfF S Peptidase M16
ADEHOEND_00866 1.4e-242 ymfH S zinc protease
ADEHOEND_00867 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
ADEHOEND_00868 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
ADEHOEND_00869 2.7e-143 ymfK S Protein of unknown function (DUF3388)
ADEHOEND_00870 7.3e-116 ymfM S protein conserved in bacteria
ADEHOEND_00871 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADEHOEND_00872 1.3e-235 cinA 3.5.1.42 S Belongs to the CinA family
ADEHOEND_00873 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ADEHOEND_00874 1e-215 pbpX V Beta-lactamase
ADEHOEND_00875 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
ADEHOEND_00876 1.9e-152 ymdB S protein conserved in bacteria
ADEHOEND_00877 1.2e-36 spoVS S Stage V sporulation protein S
ADEHOEND_00878 1.9e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
ADEHOEND_00879 3e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
ADEHOEND_00880 1.9e-294 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADEHOEND_00881 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
ADEHOEND_00882 2.2e-88 cotE S Spore coat protein
ADEHOEND_00883 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ADEHOEND_00884 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ADEHOEND_00885 2.3e-70 S Regulatory protein YrvL
ADEHOEND_00887 1.2e-97 ymcC S Membrane
ADEHOEND_00888 4.4e-109 pksA K Transcriptional regulator
ADEHOEND_00889 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
ADEHOEND_00890 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
ADEHOEND_00892 2.4e-186 pksD Q Acyl transferase domain
ADEHOEND_00893 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
ADEHOEND_00894 1.4e-37 acpK IQ Phosphopantetheine attachment site
ADEHOEND_00895 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ADEHOEND_00896 1.3e-245 pksG 2.3.3.10 I synthase
ADEHOEND_00897 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
ADEHOEND_00898 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
ADEHOEND_00899 0.0 rhiB IQ polyketide synthase
ADEHOEND_00900 0.0 pfaA Q Polyketide synthase of type I
ADEHOEND_00901 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
ADEHOEND_00902 0.0 dhbF IQ polyketide synthase
ADEHOEND_00903 0.0 pks13 HQ Beta-ketoacyl synthase
ADEHOEND_00904 6.3e-232 cypA C Cytochrome P450
ADEHOEND_00905 2e-61 ymzB
ADEHOEND_00906 8.1e-162 ymaE S Metallo-beta-lactamase superfamily
ADEHOEND_00907 8.6e-251 aprX O Belongs to the peptidase S8 family
ADEHOEND_00908 1.9e-07 K Transcriptional regulator
ADEHOEND_00909 2.1e-126 ymaC S Replication protein
ADEHOEND_00910 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
ADEHOEND_00911 8.9e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
ADEHOEND_00912 5.4e-50 ebrA P Small Multidrug Resistance protein
ADEHOEND_00914 2.1e-46 ymaF S YmaF family
ADEHOEND_00915 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ADEHOEND_00916 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
ADEHOEND_00917 8.2e-23
ADEHOEND_00918 4.5e-22 ymzA
ADEHOEND_00919 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
ADEHOEND_00920 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADEHOEND_00921 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADEHOEND_00922 2e-109 ymaB
ADEHOEND_00923 2.6e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ADEHOEND_00924 1.7e-176 spoVK O stage V sporulation protein K
ADEHOEND_00925 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ADEHOEND_00926 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
ADEHOEND_00927 1.1e-68 glnR K transcriptional
ADEHOEND_00928 7e-261 glnA 6.3.1.2 E glutamine synthetase
ADEHOEND_00929 1.1e-09
ADEHOEND_00930 1.6e-31
ADEHOEND_00931 2.1e-16
ADEHOEND_00932 8.9e-90 G SMI1-KNR4 cell-wall
ADEHOEND_00933 3.1e-113 ynaC
ADEHOEND_00934 4.1e-11 S Protein of unknown function (DUF1433)
ADEHOEND_00935 2e-97 ynaD J Acetyltransferase (GNAT) domain
ADEHOEND_00936 4.1e-73 S CAAX protease self-immunity
ADEHOEND_00937 4.7e-08 S Uncharacterised protein family (UPF0715)
ADEHOEND_00938 5.5e-20 K Cro/C1-type HTH DNA-binding domain
ADEHOEND_00939 2.1e-117 ynaE S Domain of unknown function (DUF3885)
ADEHOEND_00940 8.6e-15 ynaF
ADEHOEND_00942 8.7e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
ADEHOEND_00943 7.9e-255 xynT G MFS/sugar transport protein
ADEHOEND_00944 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
ADEHOEND_00945 6.8e-212 xylR GK ROK family
ADEHOEND_00946 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
ADEHOEND_00947 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
ADEHOEND_00948 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
ADEHOEND_00949 1.4e-254 iolT EGP Major facilitator Superfamily
ADEHOEND_00950 4.5e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADEHOEND_00952 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
ADEHOEND_00953 5.2e-15
ADEHOEND_00956 2.1e-162 S Thymidylate synthase
ADEHOEND_00958 1.7e-48 S Domain of unknown function, YrpD
ADEHOEND_00959 1.1e-69 S Domain of unknown function, YrpD
ADEHOEND_00962 7.9e-25 tatA U protein secretion
ADEHOEND_00963 1.8e-71
ADEHOEND_00964 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
ADEHOEND_00967 2.8e-52 gerAA EG Spore germination protein
ADEHOEND_00968 4.8e-144 gerAA EG Spore germination protein
ADEHOEND_00969 3.4e-88 gerLC S Spore germination protein
ADEHOEND_00970 7.7e-154 yndG S DoxX-like family
ADEHOEND_00971 2.6e-117 yndH S Domain of unknown function (DUF4166)
ADEHOEND_00972 0.0 yndJ S YndJ-like protein
ADEHOEND_00974 8.6e-139 yndL S Replication protein
ADEHOEND_00975 5.8e-74 yndM S Protein of unknown function (DUF2512)
ADEHOEND_00976 1.3e-75 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
ADEHOEND_00977 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ADEHOEND_00978 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
ADEHOEND_00979 5e-111 yneB L resolvase
ADEHOEND_00980 1.3e-32 ynzC S UPF0291 protein
ADEHOEND_00981 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ADEHOEND_00982 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
ADEHOEND_00983 1.8e-28 yneF S UPF0154 protein
ADEHOEND_00984 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
ADEHOEND_00985 7.1e-127 ccdA O cytochrome c biogenesis protein
ADEHOEND_00986 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
ADEHOEND_00987 1.9e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
ADEHOEND_00988 4.2e-74 yneK S Protein of unknown function (DUF2621)
ADEHOEND_00989 1.2e-64 hspX O Spore coat protein
ADEHOEND_00990 3.9e-19 sspP S Belongs to the SspP family
ADEHOEND_00991 2.2e-14 sspO S Belongs to the SspO family
ADEHOEND_00992 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ADEHOEND_00993 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ADEHOEND_00995 3.1e-08 sspN S Small acid-soluble spore protein N family
ADEHOEND_00996 3.9e-35 tlp S Belongs to the Tlp family
ADEHOEND_00997 2e-73 yneP S Thioesterase-like superfamily
ADEHOEND_00998 1.7e-53 yneQ
ADEHOEND_00999 4.1e-49 yneR S Belongs to the HesB IscA family
ADEHOEND_01000 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ADEHOEND_01001 8.6e-69 yccU S CoA-binding protein
ADEHOEND_01002 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ADEHOEND_01003 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ADEHOEND_01004 2.3e-12
ADEHOEND_01005 1.3e-57 ynfC
ADEHOEND_01006 1.8e-251 agcS E Sodium alanine symporter
ADEHOEND_01007 1.7e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
ADEHOEND_01009 1.2e-249 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
ADEHOEND_01010 2.4e-297 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
ADEHOEND_01011 1.6e-79 yngA S membrane
ADEHOEND_01012 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ADEHOEND_01013 5.5e-104 yngC S membrane-associated protein
ADEHOEND_01014 2.6e-230 nrnB S phosphohydrolase (DHH superfamily)
ADEHOEND_01015 1.5e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
ADEHOEND_01016 6.4e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
ADEHOEND_01017 2.9e-165 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
ADEHOEND_01018 2.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
ADEHOEND_01019 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
ADEHOEND_01020 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
ADEHOEND_01021 1.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
ADEHOEND_01022 5e-303 yngK T Glycosyl hydrolase-like 10
ADEHOEND_01023 4e-63 yngL S Protein of unknown function (DUF1360)
ADEHOEND_01024 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
ADEHOEND_01025 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ADEHOEND_01026 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ADEHOEND_01027 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ADEHOEND_01028 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ADEHOEND_01029 1.4e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
ADEHOEND_01030 5.6e-191 yoxA 5.1.3.3 G Aldose 1-epimerase
ADEHOEND_01031 2.3e-246 yoeA V MATE efflux family protein
ADEHOEND_01032 2.6e-97 yoeB S IseA DL-endopeptidase inhibitor
ADEHOEND_01034 2.2e-96 L Integrase
ADEHOEND_01035 3e-34 yoeD G Helix-turn-helix domain
ADEHOEND_01036 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
ADEHOEND_01037 2.3e-156 gltR1 K Transcriptional regulator
ADEHOEND_01038 8e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
ADEHOEND_01039 6.6e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
ADEHOEND_01040 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
ADEHOEND_01041 3.9e-154 gltC K Transcriptional regulator
ADEHOEND_01042 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ADEHOEND_01043 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ADEHOEND_01044 2e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
ADEHOEND_01045 7.7e-121 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
ADEHOEND_01046 7e-39 yoxC S Bacterial protein of unknown function (DUF948)
ADEHOEND_01047 2.5e-130 yoxB
ADEHOEND_01048 5.6e-92 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
ADEHOEND_01049 3.8e-126 V ABC-2 family transporter protein
ADEHOEND_01050 2.9e-94 V ABC-2 family transporter protein
ADEHOEND_01051 1.8e-138 V AAA domain, putative AbiEii toxin, Type IV TA system
ADEHOEND_01052 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
ADEHOEND_01053 4.9e-232 yoaB EGP Major facilitator Superfamily
ADEHOEND_01054 5.3e-278 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
ADEHOEND_01055 1.7e-70 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADEHOEND_01056 3.8e-99 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADEHOEND_01057 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ADEHOEND_01058 6.6e-32 yoaF
ADEHOEND_01059 3e-172 iolT EGP Major facilitator Superfamily
ADEHOEND_01060 1.6e-205 S Oxidoreductase family, C-terminal alpha/beta domain
ADEHOEND_01061 3.2e-151 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
ADEHOEND_01062 3.3e-90 purR K Transcriptional regulator
ADEHOEND_01063 2.2e-07
ADEHOEND_01064 7e-14
ADEHOEND_01065 1.5e-38 S Protein of unknown function (DUF4025)
ADEHOEND_01066 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
ADEHOEND_01067 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
ADEHOEND_01068 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
ADEHOEND_01069 2.3e-111 yoaK S Membrane
ADEHOEND_01070 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
ADEHOEND_01071 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
ADEHOEND_01073 7.9e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
ADEHOEND_01076 7.3e-86
ADEHOEND_01077 9.3e-172 yoaR V vancomycin resistance protein
ADEHOEND_01078 2.8e-74 yoaS S Protein of unknown function (DUF2975)
ADEHOEND_01079 4.4e-30 yozG K Transcriptional regulator
ADEHOEND_01080 5.3e-147 yoaT S Protein of unknown function (DUF817)
ADEHOEND_01081 8.6e-159 yoaU K LysR substrate binding domain
ADEHOEND_01082 1.5e-158 yijE EG EamA-like transporter family
ADEHOEND_01083 1.8e-77 yoaW
ADEHOEND_01084 4.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
ADEHOEND_01085 3.8e-165 bla 3.5.2.6 V beta-lactamase
ADEHOEND_01088 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
ADEHOEND_01089 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
ADEHOEND_01091 1.7e-40
ADEHOEND_01093 2.7e-176 T PhoQ Sensor
ADEHOEND_01094 1.2e-63 kdpC 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ADEHOEND_01095 0.0 kdpB 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ADEHOEND_01096 2.9e-272 kdpA 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ADEHOEND_01098 2.8e-84 S SMI1-KNR4 cell-wall
ADEHOEND_01099 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
ADEHOEND_01100 9.1e-101 yokH G SMI1 / KNR4 family
ADEHOEND_01101 4.4e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
ADEHOEND_01102 0.0 yobO M Pectate lyase superfamily protein
ADEHOEND_01103 1.4e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
ADEHOEND_01104 3.8e-136 yobQ K helix_turn_helix, arabinose operon control protein
ADEHOEND_01105 5.3e-141 yobR 2.3.1.1 J FR47-like protein
ADEHOEND_01106 1.3e-97 yobS K Transcriptional regulator
ADEHOEND_01107 2.8e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
ADEHOEND_01108 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
ADEHOEND_01109 6.2e-171 yobV K WYL domain
ADEHOEND_01110 1.8e-90 yobW
ADEHOEND_01111 1e-51 czrA K transcriptional
ADEHOEND_01112 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
ADEHOEND_01113 1.5e-92 yozB S membrane
ADEHOEND_01114 1.3e-142
ADEHOEND_01115 1.2e-93 yocC
ADEHOEND_01116 1.5e-188 yocD 3.4.17.13 V peptidase S66
ADEHOEND_01117 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
ADEHOEND_01118 1.7e-196 desK 2.7.13.3 T Histidine kinase
ADEHOEND_01119 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ADEHOEND_01120 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
ADEHOEND_01121 0.0 recQ 3.6.4.12 L DNA helicase
ADEHOEND_01122 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ADEHOEND_01123 3.3e-83 dksA T general stress protein
ADEHOEND_01124 6.4e-54 yocL
ADEHOEND_01125 6.6e-34
ADEHOEND_01126 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
ADEHOEND_01127 1.1e-40 yozN
ADEHOEND_01128 1.9e-36 yocN
ADEHOEND_01129 4.2e-56 yozO S Bacterial PH domain
ADEHOEND_01130 2.7e-31 yozC
ADEHOEND_01131 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
ADEHOEND_01132 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
ADEHOEND_01133 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
ADEHOEND_01134 9.9e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
ADEHOEND_01135 8.6e-168 yocS S -transporter
ADEHOEND_01136 3.5e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
ADEHOEND_01137 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
ADEHOEND_01138 0.0 yojO P Von Willebrand factor
ADEHOEND_01139 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
ADEHOEND_01140 1.5e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ADEHOEND_01141 4.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
ADEHOEND_01142 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
ADEHOEND_01143 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ADEHOEND_01145 4.2e-245 norM V Multidrug efflux pump
ADEHOEND_01146 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ADEHOEND_01147 2.1e-125 yojG S deacetylase
ADEHOEND_01148 2.2e-60 yojF S Protein of unknown function (DUF1806)
ADEHOEND_01149 1.5e-43
ADEHOEND_01150 6.6e-162 rarD S -transporter
ADEHOEND_01151 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
ADEHOEND_01152 3.4e-09
ADEHOEND_01153 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
ADEHOEND_01154 3.8e-66 yodA S tautomerase
ADEHOEND_01155 1.7e-57 yodB K transcriptional
ADEHOEND_01156 4.8e-108 yodC C nitroreductase
ADEHOEND_01157 3.8e-113 mhqD S Carboxylesterase
ADEHOEND_01158 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
ADEHOEND_01159 6.2e-28 S Protein of unknown function (DUF3311)
ADEHOEND_01160 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADEHOEND_01161 1.6e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
ADEHOEND_01162 1.7e-128 yodH Q Methyltransferase
ADEHOEND_01163 5.2e-24 yodI
ADEHOEND_01164 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
ADEHOEND_01165 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
ADEHOEND_01166 5.3e-09
ADEHOEND_01167 3.6e-54 yodL S YodL-like
ADEHOEND_01168 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
ADEHOEND_01169 2.8e-24 yozD S YozD-like protein
ADEHOEND_01171 1.4e-124 yodN
ADEHOEND_01172 1.4e-36 yozE S Belongs to the UPF0346 family
ADEHOEND_01173 2.9e-47 yokU S YokU-like protein, putative antitoxin
ADEHOEND_01174 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
ADEHOEND_01175 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
ADEHOEND_01176 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
ADEHOEND_01177 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
ADEHOEND_01178 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ADEHOEND_01179 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADEHOEND_01181 8.3e-145 yiiD K acetyltransferase
ADEHOEND_01182 1e-256 cgeD M maturation of the outermost layer of the spore
ADEHOEND_01183 3.5e-38 cgeC
ADEHOEND_01184 1.2e-65 cgeA
ADEHOEND_01185 2e-185 cgeB S Spore maturation protein
ADEHOEND_01186 5.2e-212 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
ADEHOEND_01187 1.3e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
ADEHOEND_01188 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
ADEHOEND_01189 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADEHOEND_01190 1.6e-70 ypoP K transcriptional
ADEHOEND_01191 3.8e-222 mepA V MATE efflux family protein
ADEHOEND_01192 5.5e-29 ypmT S Uncharacterized ympT
ADEHOEND_01193 1.1e-98 ypmS S protein conserved in bacteria
ADEHOEND_01194 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
ADEHOEND_01195 2.7e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
ADEHOEND_01196 3.1e-40 ypmP S Protein of unknown function (DUF2535)
ADEHOEND_01197 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ADEHOEND_01198 1.6e-185 pspF K Transcriptional regulator
ADEHOEND_01199 4.2e-110 hlyIII S protein, Hemolysin III
ADEHOEND_01200 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
ADEHOEND_01201 1.6e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ADEHOEND_01202 1.5e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ADEHOEND_01203 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
ADEHOEND_01204 7.8e-114 ypjP S YpjP-like protein
ADEHOEND_01205 3.7e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
ADEHOEND_01206 1.7e-75 yphP S Belongs to the UPF0403 family
ADEHOEND_01207 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
ADEHOEND_01208 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
ADEHOEND_01209 5.4e-107 ypgQ S phosphohydrolase
ADEHOEND_01210 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
ADEHOEND_01211 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADEHOEND_01212 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
ADEHOEND_01213 7.9e-31 cspD K Cold-shock protein
ADEHOEND_01214 3.8e-16 degR
ADEHOEND_01215 1.8e-30 S Protein of unknown function (DUF2564)
ADEHOEND_01216 2.6e-27 ypeQ S Zinc-finger
ADEHOEND_01217 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
ADEHOEND_01218 4.5e-106 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ADEHOEND_01219 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
ADEHOEND_01221 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
ADEHOEND_01222 2e-07
ADEHOEND_01223 8.5e-38 ypbS S Protein of unknown function (DUF2533)
ADEHOEND_01224 0.0 ypbR S Dynamin family
ADEHOEND_01226 7.4e-86 ypbQ S protein conserved in bacteria
ADEHOEND_01227 8.2e-207 bcsA Q Naringenin-chalcone synthase
ADEHOEND_01228 3.8e-227 pbuX F xanthine
ADEHOEND_01229 4.4e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ADEHOEND_01230 3.9e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ADEHOEND_01231 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
ADEHOEND_01232 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
ADEHOEND_01233 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
ADEHOEND_01234 7.4e-186 ptxS K transcriptional
ADEHOEND_01235 1.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ADEHOEND_01236 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ADEHOEND_01237 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
ADEHOEND_01239 1.2e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
ADEHOEND_01240 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ADEHOEND_01241 8.2e-91 ypsA S Belongs to the UPF0398 family
ADEHOEND_01242 9.5e-236 yprB L RNase_H superfamily
ADEHOEND_01243 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
ADEHOEND_01244 1.2e-80 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
ADEHOEND_01245 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
ADEHOEND_01246 6.6e-47 yppG S YppG-like protein
ADEHOEND_01248 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
ADEHOEND_01251 5.4e-186 yppC S Protein of unknown function (DUF2515)
ADEHOEND_01252 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ADEHOEND_01253 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
ADEHOEND_01254 1.8e-92 ypoC
ADEHOEND_01255 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ADEHOEND_01256 1.3e-128 dnaD L DNA replication protein DnaD
ADEHOEND_01257 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
ADEHOEND_01258 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
ADEHOEND_01259 4.9e-79 ypmB S protein conserved in bacteria
ADEHOEND_01260 1.9e-22 ypmA S Protein of unknown function (DUF4264)
ADEHOEND_01261 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
ADEHOEND_01262 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ADEHOEND_01263 6.1e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ADEHOEND_01264 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
ADEHOEND_01265 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ADEHOEND_01266 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ADEHOEND_01267 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
ADEHOEND_01268 1.7e-128 bshB1 S proteins, LmbE homologs
ADEHOEND_01269 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
ADEHOEND_01270 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
ADEHOEND_01271 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
ADEHOEND_01272 5.2e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
ADEHOEND_01273 1e-142 ypjB S sporulation protein
ADEHOEND_01274 7.6e-98 ypjA S membrane
ADEHOEND_01275 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
ADEHOEND_01276 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
ADEHOEND_01277 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
ADEHOEND_01278 4.2e-77 ypiF S Protein of unknown function (DUF2487)
ADEHOEND_01279 1.1e-98 ypiB S Belongs to the UPF0302 family
ADEHOEND_01280 4.1e-234 S COG0457 FOG TPR repeat
ADEHOEND_01281 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
ADEHOEND_01282 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
ADEHOEND_01283 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADEHOEND_01284 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
ADEHOEND_01285 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ADEHOEND_01286 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
ADEHOEND_01287 8.1e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
ADEHOEND_01288 3.9e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ADEHOEND_01289 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ADEHOEND_01290 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
ADEHOEND_01291 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ADEHOEND_01292 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ADEHOEND_01293 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
ADEHOEND_01294 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
ADEHOEND_01295 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ADEHOEND_01296 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
ADEHOEND_01297 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
ADEHOEND_01298 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
ADEHOEND_01299 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
ADEHOEND_01300 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ADEHOEND_01301 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ADEHOEND_01302 5.4e-138 yphF
ADEHOEND_01303 1.6e-18 yphE S Protein of unknown function (DUF2768)
ADEHOEND_01304 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
ADEHOEND_01305 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
ADEHOEND_01306 1.6e-28 ypzH
ADEHOEND_01307 2.5e-161 seaA S YIEGIA protein
ADEHOEND_01308 1.3e-102 yphA
ADEHOEND_01309 1e-07 S YpzI-like protein
ADEHOEND_01310 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ADEHOEND_01311 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
ADEHOEND_01312 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
ADEHOEND_01313 1.8e-23 S Family of unknown function (DUF5359)
ADEHOEND_01314 9.2e-113 ypfA M Flagellar protein YcgR
ADEHOEND_01315 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
ADEHOEND_01316 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
ADEHOEND_01317 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
ADEHOEND_01318 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
ADEHOEND_01319 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
ADEHOEND_01320 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
ADEHOEND_01321 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
ADEHOEND_01322 2.8e-81 ypbF S Protein of unknown function (DUF2663)
ADEHOEND_01323 4.6e-81 ypbE M Lysin motif
ADEHOEND_01324 2.2e-100 ypbD S metal-dependent membrane protease
ADEHOEND_01325 3.2e-286 recQ 3.6.4.12 L DNA helicase
ADEHOEND_01326 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
ADEHOEND_01327 4.7e-41 fer C Ferredoxin
ADEHOEND_01328 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ADEHOEND_01329 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADEHOEND_01330 2.2e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
ADEHOEND_01331 7.3e-195 rsiX
ADEHOEND_01332 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
ADEHOEND_01333 0.0 resE 2.7.13.3 T Histidine kinase
ADEHOEND_01334 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ADEHOEND_01335 9.7e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
ADEHOEND_01336 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
ADEHOEND_01337 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
ADEHOEND_01338 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ADEHOEND_01339 1.9e-87 spmB S Spore maturation protein
ADEHOEND_01340 3.5e-103 spmA S Spore maturation protein
ADEHOEND_01341 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
ADEHOEND_01342 7.6e-97 ypuI S Protein of unknown function (DUF3907)
ADEHOEND_01343 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ADEHOEND_01344 2.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ADEHOEND_01345 1.4e-92 ypuF S Domain of unknown function (DUF309)
ADEHOEND_01346 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ADEHOEND_01347 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
ADEHOEND_01348 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADEHOEND_01349 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
ADEHOEND_01350 2.4e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADEHOEND_01351 7.8e-55 ypuD
ADEHOEND_01352 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
ADEHOEND_01353 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
ADEHOEND_01354 3.4e-13 S PAP2 superfamily
ADEHOEND_01357 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADEHOEND_01358 3.6e-149 ypuA S Secreted protein
ADEHOEND_01359 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
ADEHOEND_01360 1.4e-273 spoVAF EG Stage V sporulation protein AF
ADEHOEND_01361 1.4e-110 spoVAEA S stage V sporulation protein
ADEHOEND_01362 2.2e-57 spoVAEB S stage V sporulation protein
ADEHOEND_01363 9e-192 spoVAD I Stage V sporulation protein AD
ADEHOEND_01364 2.3e-78 spoVAC S stage V sporulation protein AC
ADEHOEND_01365 1e-67 spoVAB S Stage V sporulation protein AB
ADEHOEND_01366 7.4e-112 spoVAA S Stage V sporulation protein AA
ADEHOEND_01367 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADEHOEND_01368 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
ADEHOEND_01369 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
ADEHOEND_01370 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
ADEHOEND_01371 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ADEHOEND_01372 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
ADEHOEND_01373 2.6e-166 xerD L recombinase XerD
ADEHOEND_01374 3.7e-37 S Protein of unknown function (DUF4227)
ADEHOEND_01375 2.4e-80 fur P Belongs to the Fur family
ADEHOEND_01376 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
ADEHOEND_01377 5.5e-30 yqkK
ADEHOEND_01378 5.5e-242 mleA 1.1.1.38 C malic enzyme
ADEHOEND_01379 2.7e-234 mleN C Na H antiporter
ADEHOEND_01380 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
ADEHOEND_01381 2.3e-184 ansA 3.5.1.1 EJ L-asparaginase
ADEHOEND_01382 4.5e-58 ansR K Transcriptional regulator
ADEHOEND_01383 1.4e-220 yqxK 3.6.4.12 L DNA helicase
ADEHOEND_01384 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
ADEHOEND_01386 4.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
ADEHOEND_01387 3.1e-12 yqkE S Protein of unknown function (DUF3886)
ADEHOEND_01388 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
ADEHOEND_01389 9.4e-39 yqkC S Protein of unknown function (DUF2552)
ADEHOEND_01390 2.8e-54 yqkB S Belongs to the HesB IscA family
ADEHOEND_01391 7.5e-194 yqkA K GrpB protein
ADEHOEND_01392 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
ADEHOEND_01393 1.8e-86 yqjY K acetyltransferase
ADEHOEND_01394 2.2e-49 S YolD-like protein
ADEHOEND_01395 9.2e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ADEHOEND_01397 6.1e-222 yqjV G Major Facilitator Superfamily
ADEHOEND_01399 1.1e-42 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ADEHOEND_01400 4.7e-08 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ADEHOEND_01401 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
ADEHOEND_01402 9.3e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
ADEHOEND_01403 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
ADEHOEND_01404 4.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
ADEHOEND_01405 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ADEHOEND_01406 0.0 rocB E arginine degradation protein
ADEHOEND_01407 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
ADEHOEND_01408 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
ADEHOEND_01409 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ADEHOEND_01410 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ADEHOEND_01411 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ADEHOEND_01412 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ADEHOEND_01413 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ADEHOEND_01414 4.5e-24 yqzJ
ADEHOEND_01415 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ADEHOEND_01416 2.6e-140 yqjF S Uncharacterized conserved protein (COG2071)
ADEHOEND_01417 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
ADEHOEND_01418 3.8e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
ADEHOEND_01419 8.7e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
ADEHOEND_01421 1.4e-98 yqjB S protein conserved in bacteria
ADEHOEND_01422 7.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
ADEHOEND_01423 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
ADEHOEND_01424 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
ADEHOEND_01425 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
ADEHOEND_01426 9.3e-77 yqiW S Belongs to the UPF0403 family
ADEHOEND_01427 9.8e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
ADEHOEND_01428 5.1e-207 norA EGP Major facilitator Superfamily
ADEHOEND_01429 6.4e-151 bmrR K helix_turn_helix, mercury resistance
ADEHOEND_01430 5.4e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ADEHOEND_01431 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
ADEHOEND_01432 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
ADEHOEND_01433 2.8e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
ADEHOEND_01434 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
ADEHOEND_01435 1.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
ADEHOEND_01436 1.1e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
ADEHOEND_01437 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
ADEHOEND_01438 4e-34 yqzF S Protein of unknown function (DUF2627)
ADEHOEND_01439 6.9e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ADEHOEND_01440 2.4e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
ADEHOEND_01441 8.4e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
ADEHOEND_01442 8.8e-212 mmgC I acyl-CoA dehydrogenase
ADEHOEND_01443 2.3e-156 hbdA 1.1.1.157 I Dehydrogenase
ADEHOEND_01444 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
ADEHOEND_01445 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
ADEHOEND_01446 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
ADEHOEND_01447 5.9e-27
ADEHOEND_01448 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
ADEHOEND_01450 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
ADEHOEND_01451 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
ADEHOEND_01452 0.0 recN L May be involved in recombinational repair of damaged DNA
ADEHOEND_01453 1.7e-78 argR K Regulates arginine biosynthesis genes
ADEHOEND_01454 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
ADEHOEND_01455 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ADEHOEND_01456 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ADEHOEND_01457 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ADEHOEND_01458 1.1e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ADEHOEND_01459 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADEHOEND_01460 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADEHOEND_01461 2.1e-67 yqhY S protein conserved in bacteria
ADEHOEND_01462 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
ADEHOEND_01463 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ADEHOEND_01464 9.9e-91 spoIIIAH S SpoIIIAH-like protein
ADEHOEND_01465 6.5e-109 spoIIIAG S stage III sporulation protein AG
ADEHOEND_01466 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
ADEHOEND_01467 2.9e-197 spoIIIAE S stage III sporulation protein AE
ADEHOEND_01468 2.3e-58 spoIIIAD S Stage III sporulation protein AD
ADEHOEND_01469 7.6e-29 spoIIIAC S stage III sporulation protein AC
ADEHOEND_01470 1.1e-84 spoIIIAB S Stage III sporulation protein
ADEHOEND_01471 1e-170 spoIIIAA S stage III sporulation protein AA
ADEHOEND_01472 7.9e-37 yqhV S Protein of unknown function (DUF2619)
ADEHOEND_01473 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ADEHOEND_01474 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
ADEHOEND_01475 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
ADEHOEND_01476 2.3e-93 yqhR S Conserved membrane protein YqhR
ADEHOEND_01477 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
ADEHOEND_01478 2.2e-61 yqhP
ADEHOEND_01479 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
ADEHOEND_01480 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
ADEHOEND_01481 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
ADEHOEND_01482 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
ADEHOEND_01483 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ADEHOEND_01484 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ADEHOEND_01485 1.8e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
ADEHOEND_01486 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
ADEHOEND_01487 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
ADEHOEND_01488 1.2e-24 sinI S Anti-repressor SinI
ADEHOEND_01489 1e-54 sinR K transcriptional
ADEHOEND_01490 1.9e-141 tasA S Cell division protein FtsN
ADEHOEND_01491 2.5e-58 sipW 3.4.21.89 U Signal peptidase
ADEHOEND_01492 2.8e-113 yqxM
ADEHOEND_01493 7.3e-54 yqzG S Protein of unknown function (DUF3889)
ADEHOEND_01494 4.4e-25 yqzE S YqzE-like protein
ADEHOEND_01495 8.8e-44 S ComG operon protein 7
ADEHOEND_01496 1.7e-34 comGF U Putative Competence protein ComGF
ADEHOEND_01497 2e-58 comGE
ADEHOEND_01498 6.3e-70 gspH NU protein transport across the cell outer membrane
ADEHOEND_01499 6.8e-47 comGC U Required for transformation and DNA binding
ADEHOEND_01500 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
ADEHOEND_01501 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ADEHOEND_01504 1.4e-173 corA P Mg2 transporter protein
ADEHOEND_01505 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
ADEHOEND_01506 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ADEHOEND_01508 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
ADEHOEND_01509 1.8e-37 yqgY S Protein of unknown function (DUF2626)
ADEHOEND_01510 9.5e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
ADEHOEND_01511 8.9e-23 yqgW S Protein of unknown function (DUF2759)
ADEHOEND_01512 6.9e-50 yqgV S Thiamine-binding protein
ADEHOEND_01513 2.7e-199 yqgU
ADEHOEND_01514 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
ADEHOEND_01515 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
ADEHOEND_01516 5.2e-181 glcK 2.7.1.2 G Glucokinase
ADEHOEND_01517 4.3e-33 yqgQ S Protein conserved in bacteria
ADEHOEND_01518 4e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
ADEHOEND_01519 2.5e-09 yqgO
ADEHOEND_01520 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ADEHOEND_01521 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ADEHOEND_01522 4.1e-133 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
ADEHOEND_01523 1.5e-41 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
ADEHOEND_01525 3.5e-50 yqzD
ADEHOEND_01526 2.1e-71 yqzC S YceG-like family
ADEHOEND_01527 8.3e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ADEHOEND_01528 3.2e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ADEHOEND_01529 4.4e-158 pstA P Phosphate transport system permease
ADEHOEND_01530 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
ADEHOEND_01531 3.4e-150 pstS P Phosphate
ADEHOEND_01532 0.0 pbpA 3.4.16.4 M penicillin-binding protein
ADEHOEND_01533 2.5e-231 yqgE EGP Major facilitator superfamily
ADEHOEND_01534 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
ADEHOEND_01535 4e-73 yqgC S protein conserved in bacteria
ADEHOEND_01536 3.9e-131 yqgB S Protein of unknown function (DUF1189)
ADEHOEND_01537 5.2e-47 yqfZ M LysM domain
ADEHOEND_01538 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ADEHOEND_01539 4.3e-62 yqfX S membrane
ADEHOEND_01540 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
ADEHOEND_01541 1.9e-77 zur P Belongs to the Fur family
ADEHOEND_01542 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
ADEHOEND_01543 7.9e-36 yqfT S Protein of unknown function (DUF2624)
ADEHOEND_01544 2.6e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ADEHOEND_01545 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ADEHOEND_01546 3.5e-12 yqfQ S YqfQ-like protein
ADEHOEND_01547 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ADEHOEND_01548 5.3e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ADEHOEND_01549 1.5e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
ADEHOEND_01550 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
ADEHOEND_01551 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ADEHOEND_01552 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ADEHOEND_01553 4.5e-88 yaiI S Belongs to the UPF0178 family
ADEHOEND_01554 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
ADEHOEND_01555 4.5e-112 ccpN K CBS domain
ADEHOEND_01556 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
ADEHOEND_01557 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
ADEHOEND_01558 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
ADEHOEND_01559 8.4e-19 S YqzL-like protein
ADEHOEND_01560 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ADEHOEND_01561 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
ADEHOEND_01562 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
ADEHOEND_01563 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ADEHOEND_01564 0.0 yqfF S membrane-associated HD superfamily hydrolase
ADEHOEND_01566 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
ADEHOEND_01567 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
ADEHOEND_01568 2.7e-45 yqfC S sporulation protein YqfC
ADEHOEND_01569 2.4e-21 yqfB
ADEHOEND_01570 4.3e-122 yqfA S UPF0365 protein
ADEHOEND_01571 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
ADEHOEND_01572 2.5e-61 yqeY S Yqey-like protein
ADEHOEND_01573 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
ADEHOEND_01574 2.3e-157 yqeW P COG1283 Na phosphate symporter
ADEHOEND_01575 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
ADEHOEND_01576 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ADEHOEND_01577 6e-174 prmA J Methylates ribosomal protein L11
ADEHOEND_01578 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ADEHOEND_01579 0.0 dnaK O Heat shock 70 kDa protein
ADEHOEND_01580 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ADEHOEND_01581 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ADEHOEND_01582 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
ADEHOEND_01583 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ADEHOEND_01584 7.2e-53 yqxA S Protein of unknown function (DUF3679)
ADEHOEND_01585 4.5e-222 spoIIP M stage II sporulation protein P
ADEHOEND_01586 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ADEHOEND_01587 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
ADEHOEND_01588 5.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
ADEHOEND_01589 4.1e-15 S YqzM-like protein
ADEHOEND_01590 0.0 comEC S Competence protein ComEC
ADEHOEND_01591 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
ADEHOEND_01592 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
ADEHOEND_01593 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ADEHOEND_01594 2.9e-139 yqeM Q Methyltransferase
ADEHOEND_01595 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ADEHOEND_01596 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
ADEHOEND_01597 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ADEHOEND_01598 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
ADEHOEND_01599 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ADEHOEND_01600 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
ADEHOEND_01601 5.3e-95 yqeG S hydrolase of the HAD superfamily
ADEHOEND_01603 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
ADEHOEND_01604 1.7e-131 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ADEHOEND_01605 2.3e-105 yqeD S SNARE associated Golgi protein
ADEHOEND_01606 1.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
ADEHOEND_01607 2e-132 yqeB
ADEHOEND_01608 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
ADEHOEND_01609 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADEHOEND_01610 4.6e-277 cisA2 L Recombinase
ADEHOEND_01611 1.5e-105 K Transcriptional regulator
ADEHOEND_01612 1.3e-123 yecA E amino acid
ADEHOEND_01614 8.4e-130 S Aspartate phosphatase response regulator
ADEHOEND_01615 1.3e-138 yvgN 1.1.1.346 S Reductase
ADEHOEND_01616 1e-70 K MerR family transcriptional regulator
ADEHOEND_01617 6e-228 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
ADEHOEND_01618 1.1e-26 yokK S SMI1 / KNR4 family
ADEHOEND_01620 1.3e-14 S SMI1-KNR4 cell-wall
ADEHOEND_01621 3.7e-47
ADEHOEND_01622 4.6e-100 S Suppressor of fused protein (SUFU)
ADEHOEND_01625 5.9e-133 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
ADEHOEND_01626 2.6e-68 S Bacteriophage holin family
ADEHOEND_01627 3e-159 xepA
ADEHOEND_01628 3.7e-10
ADEHOEND_01629 4.1e-56 xkdW S XkdW protein
ADEHOEND_01630 4.2e-219
ADEHOEND_01631 9.6e-40
ADEHOEND_01632 7.1e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
ADEHOEND_01633 5.5e-184 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
ADEHOEND_01634 1.9e-66 xkdS S Protein of unknown function (DUF2634)
ADEHOEND_01635 2.7e-31 xkdR S Protein of unknown function (DUF2577)
ADEHOEND_01636 4.2e-178 yqbQ 3.2.1.96 G NLP P60 protein
ADEHOEND_01637 7.6e-113 xkdP S Lysin motif
ADEHOEND_01638 0.0 xkdO L Transglycosylase SLT domain
ADEHOEND_01639 1.2e-66 S Phage XkdN-like tail assembly chaperone protein, TAC
ADEHOEND_01640 3.6e-76 xkdM S Phage tail tube protein
ADEHOEND_01641 6.3e-252 xkdK S Phage tail sheath C-terminal domain
ADEHOEND_01642 1.8e-24
ADEHOEND_01643 7.8e-76
ADEHOEND_01644 3.3e-86 S Bacteriophage HK97-gp10, putative tail-component
ADEHOEND_01645 1.2e-61 yqbH S Domain of unknown function (DUF3599)
ADEHOEND_01646 3.9e-66 S Protein of unknown function (DUF3199)
ADEHOEND_01647 1.6e-46 S YqbF, hypothetical protein domain
ADEHOEND_01648 7.1e-167 xkdG S Phage capsid family
ADEHOEND_01649 2.8e-118 yqbD 2.1.1.72 L Putative phage serine protease XkdF
ADEHOEND_01650 6.1e-63
ADEHOEND_01651 1.4e-151 S Phage Mu protein F like protein
ADEHOEND_01652 3.3e-286 yqbA S portal protein
ADEHOEND_01653 2.4e-253 S phage terminase, large subunit
ADEHOEND_01654 6.3e-107 yqaS L DNA packaging
ADEHOEND_01656 6.5e-81 L Transposase
ADEHOEND_01657 1.6e-166
ADEHOEND_01658 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
ADEHOEND_01659 7.2e-74 rusA L Endodeoxyribonuclease RusA
ADEHOEND_01661 5.9e-168 xkdC L IstB-like ATP binding protein
ADEHOEND_01662 1e-122 3.1.3.16 L DnaD domain protein
ADEHOEND_01663 2.5e-155 recT L RecT family
ADEHOEND_01664 1.4e-162 yqaJ L YqaJ-like viral recombinase domain
ADEHOEND_01668 1.2e-103
ADEHOEND_01670 1.2e-17 K Helix-turn-helix XRE-family like proteins
ADEHOEND_01671 1.1e-32 K sequence-specific DNA binding
ADEHOEND_01673 1.2e-97 adk 2.7.4.3 F adenylate kinase activity
ADEHOEND_01675 1.2e-94 yqaB E IrrE N-terminal-like domain
ADEHOEND_01676 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADEHOEND_01677 3.6e-112 tetR3 K Transcriptional regulator
ADEHOEND_01678 2e-215 mepA V Multidrug transporter MatE
ADEHOEND_01679 7e-166 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
ADEHOEND_01680 5.4e-112 yrkJ S membrane transporter protein
ADEHOEND_01681 3.5e-35 yrkI O Belongs to the sulfur carrier protein TusA family
ADEHOEND_01682 9.3e-206 yrkH P Rhodanese Homology Domain
ADEHOEND_01683 2.3e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
ADEHOEND_01684 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
ADEHOEND_01685 7.8e-39 yrkD S protein conserved in bacteria
ADEHOEND_01686 5.5e-106 yrkC G Cupin domain
ADEHOEND_01687 4.2e-147 bltR K helix_turn_helix, mercury resistance
ADEHOEND_01688 3.9e-210 blt EGP Major facilitator Superfamily
ADEHOEND_01689 5.9e-82 bltD 2.3.1.57 K FR47-like protein
ADEHOEND_01690 2.5e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
ADEHOEND_01691 3.9e-16 S YrzO-like protein
ADEHOEND_01692 1.6e-169 yrdR EG EamA-like transporter family
ADEHOEND_01693 3e-159 yrdQ K Transcriptional regulator
ADEHOEND_01694 2.3e-198 trkA P Oxidoreductase
ADEHOEND_01695 4e-149 czcD P COG1230 Co Zn Cd efflux system component
ADEHOEND_01696 1.3e-66 yodA S tautomerase
ADEHOEND_01697 5e-162 gltR K LysR substrate binding domain
ADEHOEND_01698 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
ADEHOEND_01699 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
ADEHOEND_01700 9.6e-138 azlC E AzlC protein
ADEHOEND_01701 5.3e-78 bkdR K helix_turn_helix ASNC type
ADEHOEND_01702 1.1e-40 yrdF K ribonuclease inhibitor
ADEHOEND_01703 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
ADEHOEND_01704 3.3e-57 S Protein of unknown function (DUF2568)
ADEHOEND_01705 2.4e-89 yrdA S DinB family
ADEHOEND_01706 4.2e-166 aadK G Streptomycin adenylyltransferase
ADEHOEND_01707 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
ADEHOEND_01708 4.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ADEHOEND_01709 1.6e-123 yrpD S Domain of unknown function, YrpD
ADEHOEND_01711 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
ADEHOEND_01712 2.4e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
ADEHOEND_01713 1.3e-187 yrpG C Aldo/keto reductase family
ADEHOEND_01714 3.4e-223 yraO C Citrate transporter
ADEHOEND_01715 3.4e-163 yraN K Transcriptional regulator
ADEHOEND_01716 1.6e-205 yraM S PrpF protein
ADEHOEND_01718 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
ADEHOEND_01719 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ADEHOEND_01720 3.2e-155 S Alpha beta hydrolase
ADEHOEND_01721 1.7e-60 T sh3 domain protein
ADEHOEND_01722 2.4e-61 T sh3 domain protein
ADEHOEND_01723 1.3e-66 E Glyoxalase-like domain
ADEHOEND_01724 5.3e-37 yraG
ADEHOEND_01725 6.4e-63 yraF M Spore coat protein
ADEHOEND_01726 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
ADEHOEND_01727 2.6e-26 yraE
ADEHOEND_01728 1.1e-49 yraD M Spore coat protein
ADEHOEND_01729 4.3e-47 yraB K helix_turn_helix, mercury resistance
ADEHOEND_01730 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
ADEHOEND_01731 3.2e-200 adhA 1.1.1.1 C alcohol dehydrogenase
ADEHOEND_01732 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
ADEHOEND_01733 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
ADEHOEND_01734 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
ADEHOEND_01735 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
ADEHOEND_01736 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
ADEHOEND_01737 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
ADEHOEND_01738 0.0 levR K PTS system fructose IIA component
ADEHOEND_01739 1e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
ADEHOEND_01740 3.6e-106 yrhP E LysE type translocator
ADEHOEND_01741 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
ADEHOEND_01742 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
ADEHOEND_01743 3.8e-151 rsiV S Protein of unknown function (DUF3298)
ADEHOEND_01744 0.0 yrhL I Acyltransferase family
ADEHOEND_01745 1e-18 yrhK S YrhK-like protein
ADEHOEND_01746 7.3e-29 S Butirosin biosynthesis protein H, N-terminal
ADEHOEND_01747 3.9e-11 O Butirosin biosynthesis protein H, N-terminal
ADEHOEND_01748 1.5e-52 S dehydrogenases and related proteins
ADEHOEND_01749 6.6e-88 yodQ 3.5.1.16 E Acetylornithine deacetylase
ADEHOEND_01750 1.2e-100 EF ATP-grasp domain
ADEHOEND_01751 1.5e-180 hutH 4.3.1.23, 4.3.1.24, 4.3.1.3, 5.4.3.6 E Aromatic amino acid lyase
ADEHOEND_01752 2e-46 hopR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
ADEHOEND_01753 7.2e-104 Q TIGRFAM amino acid adenylation domain
ADEHOEND_01754 8.3e-63 S ABC-2 family transporter protein
ADEHOEND_01755 5.7e-64 S ABC-2 family transporter protein
ADEHOEND_01756 9.4e-117 S ATPases associated with a variety of cellular activities
ADEHOEND_01757 2.6e-119 wbpP 5.1.3.2, 5.1.3.7 GM NmrA-like family
ADEHOEND_01758 4.3e-168 capL C PFAM UDP-glucose GDP-mannose dehydrogenase
ADEHOEND_01759 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
ADEHOEND_01760 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
ADEHOEND_01761 7.2e-95 yrhH Q methyltransferase
ADEHOEND_01764 1.8e-142 focA P Formate nitrite
ADEHOEND_01765 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
ADEHOEND_01766 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
ADEHOEND_01767 1.4e-78 yrhD S Protein of unknown function (DUF1641)
ADEHOEND_01768 4.6e-35 yrhC S YrhC-like protein
ADEHOEND_01769 1.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
ADEHOEND_01770 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
ADEHOEND_01771 1.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ADEHOEND_01772 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
ADEHOEND_01773 1e-25 yrzA S Protein of unknown function (DUF2536)
ADEHOEND_01774 2.5e-60 yrrS S Protein of unknown function (DUF1510)
ADEHOEND_01775 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
ADEHOEND_01776 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ADEHOEND_01777 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
ADEHOEND_01778 2.7e-246 yegQ O COG0826 Collagenase and related proteases
ADEHOEND_01779 3.9e-173 yegQ O Peptidase U32
ADEHOEND_01780 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
ADEHOEND_01781 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ADEHOEND_01782 1.2e-45 yrzB S Belongs to the UPF0473 family
ADEHOEND_01783 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ADEHOEND_01784 1.7e-41 yrzL S Belongs to the UPF0297 family
ADEHOEND_01785 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ADEHOEND_01786 2.7e-170 yrrI S AI-2E family transporter
ADEHOEND_01787 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
ADEHOEND_01788 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
ADEHOEND_01789 8e-109 gluC P ABC transporter
ADEHOEND_01790 7.6e-107 glnP P ABC transporter
ADEHOEND_01791 8e-08 S Protein of unknown function (DUF3918)
ADEHOEND_01792 9.8e-31 yrzR
ADEHOEND_01793 2.5e-80 yrrD S protein conserved in bacteria
ADEHOEND_01794 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ADEHOEND_01795 1.4e-15 S COG0457 FOG TPR repeat
ADEHOEND_01796 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ADEHOEND_01797 1.4e-212 iscS 2.8.1.7 E Cysteine desulfurase
ADEHOEND_01798 1.2e-70 cymR K Transcriptional regulator
ADEHOEND_01799 4.4e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
ADEHOEND_01800 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
ADEHOEND_01801 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ADEHOEND_01802 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
ADEHOEND_01804 1.5e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
ADEHOEND_01805 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ADEHOEND_01806 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADEHOEND_01807 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ADEHOEND_01808 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
ADEHOEND_01809 3e-48 yrvD S Lipopolysaccharide assembly protein A domain
ADEHOEND_01810 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
ADEHOEND_01811 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADEHOEND_01812 9.4e-49 yrzD S Post-transcriptional regulator
ADEHOEND_01813 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ADEHOEND_01814 3e-111 yrbG S membrane
ADEHOEND_01815 2.2e-73 yrzE S Protein of unknown function (DUF3792)
ADEHOEND_01816 1.1e-38 yajC U Preprotein translocase subunit YajC
ADEHOEND_01817 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
ADEHOEND_01818 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ADEHOEND_01819 2.6e-18 yrzS S Protein of unknown function (DUF2905)
ADEHOEND_01820 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ADEHOEND_01821 3.8e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ADEHOEND_01822 4.8e-93 bofC S BofC C-terminal domain
ADEHOEND_01823 4.5e-252 csbX EGP Major facilitator Superfamily
ADEHOEND_01824 4.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
ADEHOEND_01825 6.5e-119 yrzF T serine threonine protein kinase
ADEHOEND_01827 1.3e-50 S Family of unknown function (DUF5412)
ADEHOEND_01828 4.5e-261 alsT E Sodium alanine symporter
ADEHOEND_01829 1e-125 yebC K transcriptional regulatory protein
ADEHOEND_01830 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ADEHOEND_01831 8.3e-157 safA M spore coat assembly protein SafA
ADEHOEND_01832 1.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ADEHOEND_01833 1.9e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
ADEHOEND_01834 2.3e-303 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
ADEHOEND_01835 4.5e-227 nifS 2.8.1.7 E Cysteine desulfurase
ADEHOEND_01836 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
ADEHOEND_01837 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
ADEHOEND_01838 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
ADEHOEND_01839 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ADEHOEND_01840 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
ADEHOEND_01841 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
ADEHOEND_01842 4.1e-56 ysxB J ribosomal protein
ADEHOEND_01843 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
ADEHOEND_01844 9.2e-161 spoIVFB S Stage IV sporulation protein
ADEHOEND_01845 9.3e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
ADEHOEND_01846 4.7e-143 minD D Belongs to the ParA family
ADEHOEND_01847 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
ADEHOEND_01848 1.4e-84 mreD M shape-determining protein
ADEHOEND_01849 2.8e-157 mreC M Involved in formation and maintenance of cell shape
ADEHOEND_01850 1.8e-184 mreB D Rod shape-determining protein MreB
ADEHOEND_01851 1.3e-125 radC E Belongs to the UPF0758 family
ADEHOEND_01852 8.3e-102 maf D septum formation protein Maf
ADEHOEND_01853 8.4e-166 spoIIB S Sporulation related domain
ADEHOEND_01854 8.3e-126 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
ADEHOEND_01855 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ADEHOEND_01856 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ADEHOEND_01857 1.6e-25
ADEHOEND_01858 1.7e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ADEHOEND_01859 2.2e-222 spoVID M stage VI sporulation protein D
ADEHOEND_01860 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
ADEHOEND_01861 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
ADEHOEND_01862 7.1e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
ADEHOEND_01863 9.6e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
ADEHOEND_01864 3.6e-146 hemX O cytochrome C
ADEHOEND_01865 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ADEHOEND_01866 1.4e-89 ysxD
ADEHOEND_01867 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
ADEHOEND_01868 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ADEHOEND_01869 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
ADEHOEND_01870 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ADEHOEND_01871 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ADEHOEND_01872 2.3e-187 ysoA H Tetratricopeptide repeat
ADEHOEND_01873 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ADEHOEND_01874 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ADEHOEND_01875 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
ADEHOEND_01876 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADEHOEND_01877 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ADEHOEND_01878 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
ADEHOEND_01879 0.0 ilvB 2.2.1.6 E Acetolactate synthase
ADEHOEND_01881 7.6e-82 ysnE K acetyltransferase
ADEHOEND_01882 9.1e-134 ysnF S protein conserved in bacteria
ADEHOEND_01884 1.4e-92 ysnB S Phosphoesterase
ADEHOEND_01885 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ADEHOEND_01886 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ADEHOEND_01887 2.9e-196 gerM S COG5401 Spore germination protein
ADEHOEND_01888 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ADEHOEND_01889 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
ADEHOEND_01890 3.3e-30 gerE K Transcriptional regulator
ADEHOEND_01891 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
ADEHOEND_01892 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
ADEHOEND_01893 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
ADEHOEND_01894 2.4e-107 sdhC C succinate dehydrogenase
ADEHOEND_01895 1.2e-79 yslB S Protein of unknown function (DUF2507)
ADEHOEND_01896 3.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
ADEHOEND_01897 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ADEHOEND_01898 2e-52 trxA O Belongs to the thioredoxin family
ADEHOEND_01899 5.7e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
ADEHOEND_01901 2.1e-177 etfA C Electron transfer flavoprotein
ADEHOEND_01902 4.5e-135 etfB C Electron transfer flavoprotein
ADEHOEND_01903 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
ADEHOEND_01904 2.7e-100 fadR K Transcriptional regulator
ADEHOEND_01905 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
ADEHOEND_01906 7.3e-68 yshE S membrane
ADEHOEND_01907 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ADEHOEND_01908 0.0 polX L COG1796 DNA polymerase IV (family X)
ADEHOEND_01909 1.3e-85 cvpA S membrane protein, required for colicin V production
ADEHOEND_01910 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ADEHOEND_01911 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ADEHOEND_01912 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ADEHOEND_01913 2.3e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ADEHOEND_01914 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADEHOEND_01915 5.8e-32 sspI S Belongs to the SspI family
ADEHOEND_01916 9.2e-206 ysfB KT regulator
ADEHOEND_01917 8.2e-260 glcD 1.1.3.15 C Glycolate oxidase subunit
ADEHOEND_01918 5.8e-255 glcF C Glycolate oxidase
ADEHOEND_01919 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
ADEHOEND_01920 0.0 cstA T Carbon starvation protein
ADEHOEND_01921 1.7e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
ADEHOEND_01922 3.8e-143 araQ G transport system permease
ADEHOEND_01923 4.2e-167 araP G carbohydrate transport
ADEHOEND_01924 2e-252 araN G carbohydrate transport
ADEHOEND_01925 1.8e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
ADEHOEND_01926 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
ADEHOEND_01927 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
ADEHOEND_01928 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
ADEHOEND_01929 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
ADEHOEND_01930 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
ADEHOEND_01931 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
ADEHOEND_01932 9.2e-68 ysdB S Sigma-w pathway protein YsdB
ADEHOEND_01933 7.5e-45 ysdA S Membrane
ADEHOEND_01934 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ADEHOEND_01935 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
ADEHOEND_01936 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ADEHOEND_01938 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
ADEHOEND_01939 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
ADEHOEND_01940 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
ADEHOEND_01941 0.0 lytS 2.7.13.3 T Histidine kinase
ADEHOEND_01942 1.5e-149 ysaA S HAD-hyrolase-like
ADEHOEND_01943 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ADEHOEND_01944 3.8e-159 ytxC S YtxC-like family
ADEHOEND_01945 4.9e-111 ytxB S SNARE associated Golgi protein
ADEHOEND_01946 3e-173 dnaI L Primosomal protein DnaI
ADEHOEND_01947 3.5e-266 dnaB L Membrane attachment protein
ADEHOEND_01948 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADEHOEND_01949 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ADEHOEND_01950 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ADEHOEND_01951 9.9e-67 ytcD K Transcriptional regulator
ADEHOEND_01952 4.9e-205 ytbD EGP Major facilitator Superfamily
ADEHOEND_01953 8.9e-161 ytbE S reductase
ADEHOEND_01954 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ADEHOEND_01955 1.1e-107 ytaF P Probably functions as a manganese efflux pump
ADEHOEND_01956 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ADEHOEND_01957 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADEHOEND_01958 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
ADEHOEND_01959 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ADEHOEND_01960 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
ADEHOEND_01961 1.8e-242 icd 1.1.1.42 C isocitrate
ADEHOEND_01962 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
ADEHOEND_01963 4.7e-71 yeaL S membrane
ADEHOEND_01964 9.9e-192 ytvI S sporulation integral membrane protein YtvI
ADEHOEND_01965 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
ADEHOEND_01966 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
ADEHOEND_01967 7.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
ADEHOEND_01968 8.1e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
ADEHOEND_01969 3.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ADEHOEND_01970 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
ADEHOEND_01971 0.0 dnaE 2.7.7.7 L DNA polymerase
ADEHOEND_01972 3.2e-56 ytrH S Sporulation protein YtrH
ADEHOEND_01973 2.4e-68 ytrI
ADEHOEND_01974 9.2e-29
ADEHOEND_01975 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
ADEHOEND_01976 2.4e-47 ytpI S YtpI-like protein
ADEHOEND_01977 8e-241 ytoI K transcriptional regulator containing CBS domains
ADEHOEND_01978 1.2e-158 ytnM S membrane transporter protein
ADEHOEND_01979 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
ADEHOEND_01980 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
ADEHOEND_01981 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADEHOEND_01982 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
ADEHOEND_01983 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADEHOEND_01984 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
ADEHOEND_01985 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
ADEHOEND_01986 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
ADEHOEND_01987 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
ADEHOEND_01988 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
ADEHOEND_01989 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
ADEHOEND_01990 2.9e-173 ytlI K LysR substrate binding domain
ADEHOEND_01991 1.7e-130 ytkL S Belongs to the UPF0173 family
ADEHOEND_01992 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ADEHOEND_01994 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
ADEHOEND_01995 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
ADEHOEND_01996 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
ADEHOEND_01997 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADEHOEND_01998 7e-165 ytxK 2.1.1.72 L DNA methylase
ADEHOEND_01999 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ADEHOEND_02000 8.7e-70 ytfJ S Sporulation protein YtfJ
ADEHOEND_02001 5.6e-116 ytfI S Protein of unknown function (DUF2953)
ADEHOEND_02002 1.3e-87 yteJ S RDD family
ADEHOEND_02003 7.1e-181 sppA OU signal peptide peptidase SppA
ADEHOEND_02004 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ADEHOEND_02005 0.0 ytcJ S amidohydrolase
ADEHOEND_02006 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
ADEHOEND_02007 2e-29 sspB S spore protein
ADEHOEND_02008 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ADEHOEND_02009 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
ADEHOEND_02010 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
ADEHOEND_02011 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ADEHOEND_02012 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
ADEHOEND_02013 3.4e-109 yttP K Transcriptional regulator
ADEHOEND_02014 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
ADEHOEND_02015 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
ADEHOEND_02016 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ADEHOEND_02018 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ADEHOEND_02019 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
ADEHOEND_02020 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
ADEHOEND_02021 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
ADEHOEND_02022 1.6e-224 acuC BQ histone deacetylase
ADEHOEND_02023 1.4e-125 motS N Flagellar motor protein
ADEHOEND_02024 2.1e-146 motA N flagellar motor
ADEHOEND_02025 3.8e-182 ccpA K catabolite control protein A
ADEHOEND_02026 2.4e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
ADEHOEND_02027 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
ADEHOEND_02028 6.6e-17 ytxH S COG4980 Gas vesicle protein
ADEHOEND_02029 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ADEHOEND_02030 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
ADEHOEND_02031 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
ADEHOEND_02032 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ADEHOEND_02033 9.8e-149 ytpQ S Belongs to the UPF0354 family
ADEHOEND_02034 4.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
ADEHOEND_02035 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
ADEHOEND_02036 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
ADEHOEND_02037 2.2e-51 ytzB S small secreted protein
ADEHOEND_02038 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
ADEHOEND_02039 5.1e-148 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
ADEHOEND_02040 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ADEHOEND_02041 2e-45 ytzH S YtzH-like protein
ADEHOEND_02042 1e-150 ytmP 2.7.1.89 M Phosphotransferase
ADEHOEND_02043 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
ADEHOEND_02044 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
ADEHOEND_02045 1.3e-165 ytlQ
ADEHOEND_02046 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ADEHOEND_02047 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ADEHOEND_02048 7.1e-272 pepV 3.5.1.18 E Dipeptidase
ADEHOEND_02049 7.2e-226 pbuO S permease
ADEHOEND_02050 1.5e-203 ythQ U Bacterial ABC transporter protein EcsB
ADEHOEND_02051 9e-130 ythP V ABC transporter
ADEHOEND_02052 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
ADEHOEND_02053 1.8e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ADEHOEND_02054 3.6e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ADEHOEND_02055 1.4e-231 ytfP S HI0933-like protein
ADEHOEND_02056 7.5e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
ADEHOEND_02057 3.1e-26 yteV S Sporulation protein Cse60
ADEHOEND_02058 4.8e-117 yteU S Integral membrane protein
ADEHOEND_02059 2.6e-249 yteT S Oxidoreductase family, C-terminal alpha/beta domain
ADEHOEND_02060 4.6e-73 yteS G transport
ADEHOEND_02061 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
ADEHOEND_02062 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
ADEHOEND_02063 0.0 ytdP K Transcriptional regulator
ADEHOEND_02064 1.8e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
ADEHOEND_02065 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
ADEHOEND_02066 1.2e-135 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
ADEHOEND_02067 1.7e-221 bioI 1.14.14.46 C Cytochrome P450
ADEHOEND_02068 5.4e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ADEHOEND_02069 1.9e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ADEHOEND_02070 1.8e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
ADEHOEND_02071 3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
ADEHOEND_02072 3.1e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
ADEHOEND_02073 7.8e-171 ytaP S Acetyl xylan esterase (AXE1)
ADEHOEND_02074 1.5e-189 msmR K Transcriptional regulator
ADEHOEND_02075 1.9e-247 msmE G Bacterial extracellular solute-binding protein
ADEHOEND_02076 1.4e-167 amyD P ABC transporter
ADEHOEND_02077 1.1e-142 amyC P ABC transporter (permease)
ADEHOEND_02078 5.8e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
ADEHOEND_02079 2.1e-51 ytwF P Sulfurtransferase
ADEHOEND_02080 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
ADEHOEND_02081 7.7e-55 ytvB S Protein of unknown function (DUF4257)
ADEHOEND_02082 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
ADEHOEND_02083 7.3e-209 yttB EGP Major facilitator Superfamily
ADEHOEND_02084 1.3e-41 yttA 2.7.13.3 S Pfam Transposase IS66
ADEHOEND_02085 0.0 bceB V ABC transporter (permease)
ADEHOEND_02086 1.1e-138 bceA V ABC transporter, ATP-binding protein
ADEHOEND_02087 1.8e-184 T PhoQ Sensor
ADEHOEND_02088 1.1e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ADEHOEND_02089 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
ADEHOEND_02090 3.1e-127 ytrE V ABC transporter, ATP-binding protein
ADEHOEND_02091 5.9e-148
ADEHOEND_02092 8.3e-166 P ABC-2 family transporter protein
ADEHOEND_02093 4.2e-161 ytrB P abc transporter atp-binding protein
ADEHOEND_02094 5.1e-66 ytrA K GntR family transcriptional regulator
ADEHOEND_02096 6.7e-41 ytzC S Protein of unknown function (DUF2524)
ADEHOEND_02097 2.1e-190 yhcC S Fe-S oxidoreductase
ADEHOEND_02098 3.3e-106 ytqB J Putative rRNA methylase
ADEHOEND_02099 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
ADEHOEND_02100 5.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
ADEHOEND_02101 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ADEHOEND_02102 1.1e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
ADEHOEND_02103 0.0 asnB 6.3.5.4 E Asparagine synthase
ADEHOEND_02104 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ADEHOEND_02105 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ADEHOEND_02106 1.2e-38 ytmB S Protein of unknown function (DUF2584)
ADEHOEND_02107 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
ADEHOEND_02108 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
ADEHOEND_02109 1.4e-144 ytlC P ABC transporter
ADEHOEND_02110 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
ADEHOEND_02111 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
ADEHOEND_02112 5.4e-63 ytkC S Bacteriophage holin family
ADEHOEND_02113 2.1e-76 dps P Belongs to the Dps family
ADEHOEND_02115 2.4e-72 ytkA S YtkA-like
ADEHOEND_02116 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ADEHOEND_02117 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
ADEHOEND_02118 3.6e-41 rpmE2 J Ribosomal protein L31
ADEHOEND_02119 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
ADEHOEND_02120 1.8e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
ADEHOEND_02121 1.1e-24 S Domain of Unknown Function (DUF1540)
ADEHOEND_02122 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
ADEHOEND_02123 8.8e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
ADEHOEND_02124 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
ADEHOEND_02125 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
ADEHOEND_02126 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
ADEHOEND_02127 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
ADEHOEND_02128 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ADEHOEND_02129 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
ADEHOEND_02130 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ADEHOEND_02131 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
ADEHOEND_02132 2.6e-132 dksA T COG1734 DnaK suppressor protein
ADEHOEND_02133 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
ADEHOEND_02134 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ADEHOEND_02135 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
ADEHOEND_02136 3.6e-235 ytcC M Glycosyltransferase Family 4
ADEHOEND_02138 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
ADEHOEND_02139 1.8e-217 cotSA M Glycosyl transferases group 1
ADEHOEND_02140 1.8e-206 cotI S Spore coat protein
ADEHOEND_02141 9.9e-77 tspO T membrane
ADEHOEND_02142 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
ADEHOEND_02143 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
ADEHOEND_02144 6.4e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
ADEHOEND_02145 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ADEHOEND_02146 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ADEHOEND_02155 7.8e-08
ADEHOEND_02156 1.3e-09
ADEHOEND_02163 2e-08
ADEHOEND_02168 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
ADEHOEND_02169 1.4e-92 M1-753 M FR47-like protein
ADEHOEND_02170 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
ADEHOEND_02171 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
ADEHOEND_02172 3.9e-84 yuaE S DinB superfamily
ADEHOEND_02173 7.4e-106 yuaD
ADEHOEND_02174 1.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
ADEHOEND_02175 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
ADEHOEND_02176 2.7e-94 yuaC K Belongs to the GbsR family
ADEHOEND_02177 2.2e-91 yuaB
ADEHOEND_02178 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
ADEHOEND_02179 1.6e-236 ktrB P Potassium
ADEHOEND_02180 1e-38 yiaA S yiaA/B two helix domain
ADEHOEND_02181 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ADEHOEND_02182 2.4e-273 yubD P Major Facilitator Superfamily
ADEHOEND_02183 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
ADEHOEND_02185 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
ADEHOEND_02186 1.3e-194 yubA S transporter activity
ADEHOEND_02187 3.3e-183 ygjR S Oxidoreductase
ADEHOEND_02188 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
ADEHOEND_02189 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
ADEHOEND_02190 5.1e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
ADEHOEND_02191 6.6e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
ADEHOEND_02192 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
ADEHOEND_02193 7.3e-238 mcpA NT chemotaxis protein
ADEHOEND_02194 4.7e-293 mcpA NT chemotaxis protein
ADEHOEND_02195 2.4e-220 mcpA NT chemotaxis protein
ADEHOEND_02196 3.2e-225 mcpA NT chemotaxis protein
ADEHOEND_02197 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
ADEHOEND_02198 2.3e-35
ADEHOEND_02199 1.8e-71 yugU S Uncharacterised protein family UPF0047
ADEHOEND_02200 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
ADEHOEND_02201 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
ADEHOEND_02202 1.4e-116 yugP S Zn-dependent protease
ADEHOEND_02203 2.3e-38
ADEHOEND_02204 1.1e-53 mstX S Membrane-integrating protein Mistic
ADEHOEND_02205 2.2e-182 yugO P COG1226 Kef-type K transport systems
ADEHOEND_02206 1.3e-72 yugN S YugN-like family
ADEHOEND_02208 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
ADEHOEND_02209 2.8e-229 yugK C Dehydrogenase
ADEHOEND_02210 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
ADEHOEND_02211 1.1e-34 yuzA S Domain of unknown function (DUF378)
ADEHOEND_02212 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
ADEHOEND_02213 2.1e-199 yugH 2.6.1.1 E Aminotransferase
ADEHOEND_02214 1.6e-85 alaR K Transcriptional regulator
ADEHOEND_02215 4.9e-156 yugF I Hydrolase
ADEHOEND_02216 1.6e-39 yugE S Domain of unknown function (DUF1871)
ADEHOEND_02217 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
ADEHOEND_02218 4.6e-233 T PhoQ Sensor
ADEHOEND_02219 3.1e-68 kapB G Kinase associated protein B
ADEHOEND_02220 1.9e-115 kapD L the KinA pathway to sporulation
ADEHOEND_02222 3.8e-185 yuxJ EGP Major facilitator Superfamily
ADEHOEND_02223 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
ADEHOEND_02224 1.8e-74 yuxK S protein conserved in bacteria
ADEHOEND_02225 6.3e-78 yufK S Family of unknown function (DUF5366)
ADEHOEND_02226 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
ADEHOEND_02227 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
ADEHOEND_02228 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
ADEHOEND_02229 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
ADEHOEND_02230 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
ADEHOEND_02231 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
ADEHOEND_02232 1.3e-233 maeN C COG3493 Na citrate symporter
ADEHOEND_02233 3.2e-14
ADEHOEND_02234 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
ADEHOEND_02235 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ADEHOEND_02236 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ADEHOEND_02237 6.4e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ADEHOEND_02238 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ADEHOEND_02239 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ADEHOEND_02240 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
ADEHOEND_02241 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
ADEHOEND_02242 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ADEHOEND_02243 0.0 comP 2.7.13.3 T Histidine kinase
ADEHOEND_02245 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
ADEHOEND_02248 3.2e-22 yuzC
ADEHOEND_02249 1.8e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
ADEHOEND_02250 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ADEHOEND_02251 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
ADEHOEND_02252 7.9e-67 yueI S Protein of unknown function (DUF1694)
ADEHOEND_02253 2.8e-38 yueH S YueH-like protein
ADEHOEND_02254 2.1e-32 yueG S Spore germination protein gerPA/gerPF
ADEHOEND_02255 1.9e-190 yueF S transporter activity
ADEHOEND_02256 6.1e-72 S Protein of unknown function (DUF2283)
ADEHOEND_02257 2.9e-24 S Protein of unknown function (DUF2642)
ADEHOEND_02258 4.8e-96 yueE S phosphohydrolase
ADEHOEND_02259 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ADEHOEND_02260 6.6e-65 yueC S Family of unknown function (DUF5383)
ADEHOEND_02261 0.0 esaA S type VII secretion protein EsaA
ADEHOEND_02262 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
ADEHOEND_02263 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
ADEHOEND_02264 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
ADEHOEND_02265 2.8e-45 esxA S Belongs to the WXG100 family
ADEHOEND_02266 6.5e-229 yukF QT Transcriptional regulator
ADEHOEND_02267 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
ADEHOEND_02268 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
ADEHOEND_02269 3.8e-36 mbtH S MbtH-like protein
ADEHOEND_02270 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ADEHOEND_02271 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
ADEHOEND_02272 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
ADEHOEND_02273 6.6e-226 entC 5.4.4.2 HQ Isochorismate synthase
ADEHOEND_02274 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ADEHOEND_02275 1.3e-167 besA S Putative esterase
ADEHOEND_02276 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
ADEHOEND_02277 4.4e-93 bioY S Biotin biosynthesis protein
ADEHOEND_02278 3.9e-211 yuiF S antiporter
ADEHOEND_02279 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ADEHOEND_02280 1.2e-77 yuiD S protein conserved in bacteria
ADEHOEND_02281 5.6e-118 yuiC S protein conserved in bacteria
ADEHOEND_02282 8.4e-27 yuiB S Putative membrane protein
ADEHOEND_02283 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
ADEHOEND_02284 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
ADEHOEND_02286 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ADEHOEND_02287 1e-116 paiB K Putative FMN-binding domain
ADEHOEND_02288 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ADEHOEND_02289 3.7e-63 erpA S Belongs to the HesB IscA family
ADEHOEND_02290 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ADEHOEND_02291 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ADEHOEND_02292 3.2e-39 yuzB S Belongs to the UPF0349 family
ADEHOEND_02293 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
ADEHOEND_02294 3.5e-57 yuzD S protein conserved in bacteria
ADEHOEND_02295 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
ADEHOEND_02296 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
ADEHOEND_02297 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
ADEHOEND_02298 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ADEHOEND_02299 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
ADEHOEND_02300 2.9e-198 yutH S Spore coat protein
ADEHOEND_02301 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
ADEHOEND_02302 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ADEHOEND_02303 8.6e-75 yutE S Protein of unknown function DUF86
ADEHOEND_02304 9.7e-48 yutD S protein conserved in bacteria
ADEHOEND_02305 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ADEHOEND_02306 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ADEHOEND_02307 3.8e-195 lytH M Peptidase, M23
ADEHOEND_02308 4.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
ADEHOEND_02309 5.3e-47 yunC S Domain of unknown function (DUF1805)
ADEHOEND_02310 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
ADEHOEND_02311 1e-140 yunE S membrane transporter protein
ADEHOEND_02312 7.3e-171 yunF S Protein of unknown function DUF72
ADEHOEND_02313 6.7e-62 yunG
ADEHOEND_02314 7.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
ADEHOEND_02315 7.5e-302 pucR QT COG2508 Regulator of polyketide synthase expression
ADEHOEND_02316 2.1e-236 pbuX F Permease family
ADEHOEND_02317 1.3e-222 pbuX F xanthine
ADEHOEND_02318 7.3e-283 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
ADEHOEND_02319 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
ADEHOEND_02320 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
ADEHOEND_02321 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
ADEHOEND_02322 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
ADEHOEND_02323 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
ADEHOEND_02324 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ADEHOEND_02326 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
ADEHOEND_02327 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
ADEHOEND_02328 2.4e-169 bsn L Ribonuclease
ADEHOEND_02329 1.2e-205 msmX P Belongs to the ABC transporter superfamily
ADEHOEND_02330 1.1e-135 yurK K UTRA
ADEHOEND_02331 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
ADEHOEND_02332 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
ADEHOEND_02333 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
ADEHOEND_02334 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
ADEHOEND_02335 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
ADEHOEND_02336 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
ADEHOEND_02337 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
ADEHOEND_02339 1e-41
ADEHOEND_02340 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ADEHOEND_02341 3.5e-271 sufB O FeS cluster assembly
ADEHOEND_02342 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
ADEHOEND_02343 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ADEHOEND_02344 9.1e-245 sufD O assembly protein SufD
ADEHOEND_02345 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
ADEHOEND_02346 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADEHOEND_02347 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
ADEHOEND_02348 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
ADEHOEND_02349 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ADEHOEND_02350 2.4e-56 yusD S SCP-2 sterol transfer family
ADEHOEND_02351 5.6e-55 traF CO Thioredoxin
ADEHOEND_02352 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
ADEHOEND_02353 1.1e-39 yusG S Protein of unknown function (DUF2553)
ADEHOEND_02354 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
ADEHOEND_02355 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
ADEHOEND_02356 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
ADEHOEND_02357 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
ADEHOEND_02358 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
ADEHOEND_02359 8.1e-09 S YuzL-like protein
ADEHOEND_02360 7.1e-164 fadM E Proline dehydrogenase
ADEHOEND_02361 5.1e-40
ADEHOEND_02362 5.4e-53 yusN M Coat F domain
ADEHOEND_02363 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
ADEHOEND_02364 3.2e-292 yusP P Major facilitator superfamily
ADEHOEND_02365 2.7e-64 yusQ S Tautomerase enzyme
ADEHOEND_02366 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ADEHOEND_02367 5.7e-158 yusT K LysR substrate binding domain
ADEHOEND_02368 3.8e-47 yusU S Protein of unknown function (DUF2573)
ADEHOEND_02369 1e-153 yusV 3.6.3.34 HP ABC transporter
ADEHOEND_02370 2.5e-66 S YusW-like protein
ADEHOEND_02371 1.9e-301 pepF2 E COG1164 Oligoendopeptidase F
ADEHOEND_02372 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ADEHOEND_02373 1.2e-79 dps P Ferritin-like domain
ADEHOEND_02374 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADEHOEND_02375 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ADEHOEND_02376 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
ADEHOEND_02377 4.3e-158 yuxN K Transcriptional regulator
ADEHOEND_02378 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
ADEHOEND_02379 2.3e-24 S Protein of unknown function (DUF3970)
ADEHOEND_02380 1.4e-246 gerAA EG Spore germination protein
ADEHOEND_02381 9.1e-198 gerAB E Spore germination protein
ADEHOEND_02382 3.3e-187 gerAC S Spore germination B3/ GerAC like, C-terminal
ADEHOEND_02383 8.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ADEHOEND_02384 3.5e-186 vraS 2.7.13.3 T Histidine kinase
ADEHOEND_02385 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
ADEHOEND_02386 2.3e-127 liaG S Putative adhesin
ADEHOEND_02387 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
ADEHOEND_02388 5.6e-62 liaI S membrane
ADEHOEND_02389 1.4e-226 yvqJ EGP Major facilitator Superfamily
ADEHOEND_02390 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
ADEHOEND_02391 1.1e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
ADEHOEND_02392 1.6e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEHOEND_02393 1.9e-167 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
ADEHOEND_02394 2.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ADEHOEND_02395 2.9e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
ADEHOEND_02396 0.0 T PhoQ Sensor
ADEHOEND_02397 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ADEHOEND_02398 3.6e-22
ADEHOEND_02399 9.5e-98 yvrI K RNA polymerase
ADEHOEND_02400 2.4e-19 S YvrJ protein family
ADEHOEND_02401 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
ADEHOEND_02402 3.8e-64 yvrL S Regulatory protein YrvL
ADEHOEND_02403 3.4e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
ADEHOEND_02404 2.1e-123 macB V ABC transporter, ATP-binding protein
ADEHOEND_02405 2.6e-174 M Efflux transporter rnd family, mfp subunit
ADEHOEND_02406 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
ADEHOEND_02407 3.4e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEHOEND_02408 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEHOEND_02409 7.6e-177 fhuD P ABC transporter
ADEHOEND_02411 4.9e-236 yvsH E Arginine ornithine antiporter
ADEHOEND_02412 6.5e-16 S Small spore protein J (Spore_SspJ)
ADEHOEND_02413 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
ADEHOEND_02414 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
ADEHOEND_02415 1.1e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
ADEHOEND_02416 4.9e-137 modA P COG0725 ABC-type molybdate transport system, periplasmic component
ADEHOEND_02417 3.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
ADEHOEND_02418 2.2e-156 yvgN S reductase
ADEHOEND_02419 2.1e-85 yvgO
ADEHOEND_02420 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
ADEHOEND_02421 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
ADEHOEND_02422 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ADEHOEND_02423 0.0 helD 3.6.4.12 L DNA helicase
ADEHOEND_02425 2.7e-106 yvgT S membrane
ADEHOEND_02426 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
ADEHOEND_02427 1.6e-104 bdbD O Thioredoxin
ADEHOEND_02428 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
ADEHOEND_02429 0.0 copA 3.6.3.54 P P-type ATPase
ADEHOEND_02430 1.5e-29 copZ P Copper resistance protein CopZ
ADEHOEND_02431 2.2e-48 csoR S transcriptional
ADEHOEND_02432 3.1e-195 yvaA 1.1.1.371 S Oxidoreductase
ADEHOEND_02433 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ADEHOEND_02434 0.0 yvaC S Fusaric acid resistance protein-like
ADEHOEND_02435 1.3e-72 yvaD S Family of unknown function (DUF5360)
ADEHOEND_02436 6.3e-55 yvaE P Small Multidrug Resistance protein
ADEHOEND_02437 4.1e-101 K Bacterial regulatory proteins, tetR family
ADEHOEND_02438 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ADEHOEND_02440 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ADEHOEND_02441 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ADEHOEND_02442 5.6e-143 est 3.1.1.1 S Carboxylesterase
ADEHOEND_02443 2.4e-23 secG U Preprotein translocase subunit SecG
ADEHOEND_02444 3.7e-153 yvaM S Serine aminopeptidase, S33
ADEHOEND_02445 7.5e-36 yvzC K Transcriptional
ADEHOEND_02446 4e-69 K transcriptional
ADEHOEND_02447 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
ADEHOEND_02448 2.2e-54 yodB K transcriptional
ADEHOEND_02449 1.1e-213 NT chemotaxis protein
ADEHOEND_02450 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
ADEHOEND_02451 8e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ADEHOEND_02452 5.6e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
ADEHOEND_02453 2.8e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
ADEHOEND_02454 3.3e-60 yvbF K Belongs to the GbsR family
ADEHOEND_02455 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
ADEHOEND_02456 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ADEHOEND_02457 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
ADEHOEND_02458 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
ADEHOEND_02459 3.5e-97 yvbF K Belongs to the GbsR family
ADEHOEND_02460 2.7e-101 yvbG U UPF0056 membrane protein
ADEHOEND_02461 8.6e-113 yvbH S YvbH-like oligomerisation region
ADEHOEND_02462 1.3e-120 exoY M Membrane
ADEHOEND_02463 0.0 tcaA S response to antibiotic
ADEHOEND_02464 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
ADEHOEND_02465 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ADEHOEND_02466 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
ADEHOEND_02467 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ADEHOEND_02468 3.8e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
ADEHOEND_02469 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ADEHOEND_02470 2.6e-183 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
ADEHOEND_02471 1.6e-252 araE EGP Major facilitator Superfamily
ADEHOEND_02472 5.5e-203 araR K transcriptional
ADEHOEND_02473 4.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADEHOEND_02474 5.1e-159 yvbU K Transcriptional regulator
ADEHOEND_02475 7.2e-156 yvbV EG EamA-like transporter family
ADEHOEND_02476 3.7e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
ADEHOEND_02477 2.6e-194 yvbX S Glycosyl hydrolase
ADEHOEND_02478 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
ADEHOEND_02479 1.7e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
ADEHOEND_02480 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
ADEHOEND_02481 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ADEHOEND_02482 1.6e-194 desK 2.7.13.3 T Histidine kinase
ADEHOEND_02483 6.9e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
ADEHOEND_02484 1.7e-157 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
ADEHOEND_02485 6.4e-156 rsbQ S Alpha/beta hydrolase family
ADEHOEND_02486 3.2e-196 rsbU 3.1.3.3 T response regulator
ADEHOEND_02487 2.3e-248 galA 3.2.1.89 G arabinogalactan
ADEHOEND_02488 0.0 lacA 3.2.1.23 G beta-galactosidase
ADEHOEND_02489 7.2e-150 ganQ P transport
ADEHOEND_02490 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
ADEHOEND_02491 4.4e-228 cycB G COG2182 Maltose-binding periplasmic proteins domains
ADEHOEND_02492 1.8e-184 lacR K Transcriptional regulator
ADEHOEND_02493 1e-112 yvfI K COG2186 Transcriptional regulators
ADEHOEND_02494 2.6e-308 yvfH C L-lactate permease
ADEHOEND_02495 1.2e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
ADEHOEND_02496 1e-31 yvfG S YvfG protein
ADEHOEND_02497 2.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
ADEHOEND_02498 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
ADEHOEND_02499 9e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
ADEHOEND_02500 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
ADEHOEND_02501 1.4e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ADEHOEND_02502 2.7e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
ADEHOEND_02503 1.2e-202 epsI GM pyruvyl transferase
ADEHOEND_02504 9.8e-194 epsH GT2 S Glycosyltransferase like family 2
ADEHOEND_02505 7e-206 epsG S EpsG family
ADEHOEND_02506 8.4e-218 epsF GT4 M Glycosyl transferases group 1
ADEHOEND_02507 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
ADEHOEND_02508 1.2e-221 epsD GT4 M Glycosyl transferase 4-like
ADEHOEND_02509 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
ADEHOEND_02510 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
ADEHOEND_02511 4e-122 ywqC M biosynthesis protein
ADEHOEND_02512 1.4e-75 slr K transcriptional
ADEHOEND_02513 1.6e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
ADEHOEND_02515 5.1e-92 padC Q Phenolic acid decarboxylase
ADEHOEND_02516 3.8e-73 MA20_18690 S Protein of unknown function (DUF3237)
ADEHOEND_02517 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
ADEHOEND_02518 3.2e-261 pbpE V Beta-lactamase
ADEHOEND_02519 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
ADEHOEND_02520 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
ADEHOEND_02521 1.8e-295 yveA E amino acid
ADEHOEND_02522 2.6e-106 yvdT K Transcriptional regulator
ADEHOEND_02523 1.9e-50 ykkC P Small Multidrug Resistance protein
ADEHOEND_02524 4.1e-50 sugE P Small Multidrug Resistance protein
ADEHOEND_02525 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
ADEHOEND_02526 1.1e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
ADEHOEND_02527 2.8e-182 S Patatin-like phospholipase
ADEHOEND_02529 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ADEHOEND_02530 2.8e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
ADEHOEND_02531 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
ADEHOEND_02532 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
ADEHOEND_02533 5e-154 malA S Protein of unknown function (DUF1189)
ADEHOEND_02534 3.9e-148 malD P transport
ADEHOEND_02535 5.9e-244 malC P COG1175 ABC-type sugar transport systems, permease components
ADEHOEND_02536 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
ADEHOEND_02537 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
ADEHOEND_02538 3.6e-174 yvdE K Transcriptional regulator
ADEHOEND_02539 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
ADEHOEND_02540 2.6e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
ADEHOEND_02541 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
ADEHOEND_02542 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
ADEHOEND_02543 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADEHOEND_02544 0.0 yxdM V ABC transporter (permease)
ADEHOEND_02545 5.6e-141 yvcR V ABC transporter, ATP-binding protein
ADEHOEND_02546 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
ADEHOEND_02547 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ADEHOEND_02548 1.8e-33
ADEHOEND_02549 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
ADEHOEND_02550 1.6e-36 crh G Phosphocarrier protein Chr
ADEHOEND_02551 1.4e-170 whiA K May be required for sporulation
ADEHOEND_02552 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
ADEHOEND_02553 5.7e-166 rapZ S Displays ATPase and GTPase activities
ADEHOEND_02554 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
ADEHOEND_02555 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ADEHOEND_02556 1.1e-97 usp CBM50 M protein conserved in bacteria
ADEHOEND_02557 4.5e-277 S COG0457 FOG TPR repeat
ADEHOEND_02558 0.0 msbA2 3.6.3.44 V ABC transporter
ADEHOEND_02560 0.0
ADEHOEND_02561 1.1e-73
ADEHOEND_02562 7.6e-65
ADEHOEND_02563 2.6e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
ADEHOEND_02564 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
ADEHOEND_02565 5.8e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ADEHOEND_02566 7.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ADEHOEND_02567 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
ADEHOEND_02568 5.8e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ADEHOEND_02569 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
ADEHOEND_02570 1.3e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ADEHOEND_02571 3.8e-139 yvpB NU protein conserved in bacteria
ADEHOEND_02572 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
ADEHOEND_02573 7.3e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
ADEHOEND_02574 1.2e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
ADEHOEND_02575 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
ADEHOEND_02576 1.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ADEHOEND_02577 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ADEHOEND_02578 3.3e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
ADEHOEND_02579 9.2e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ADEHOEND_02580 8.9e-133 yvoA K transcriptional
ADEHOEND_02581 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
ADEHOEND_02582 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
ADEHOEND_02583 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
ADEHOEND_02584 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
ADEHOEND_02585 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
ADEHOEND_02586 2.7e-203 yvmA EGP Major facilitator Superfamily
ADEHOEND_02587 1.2e-50 yvlD S Membrane
ADEHOEND_02588 2.6e-26 pspB KT PspC domain
ADEHOEND_02589 3.4e-168 yvlB S Putative adhesin
ADEHOEND_02590 8e-49 yvlA
ADEHOEND_02591 6.7e-34 yvkN
ADEHOEND_02592 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ADEHOEND_02593 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ADEHOEND_02594 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ADEHOEND_02595 1.2e-30 csbA S protein conserved in bacteria
ADEHOEND_02596 0.0 yvkC 2.7.9.2 GT Phosphotransferase
ADEHOEND_02597 7e-101 yvkB K Transcriptional regulator
ADEHOEND_02598 7.9e-228 yvkA EGP Major facilitator Superfamily
ADEHOEND_02599 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADEHOEND_02600 5.3e-56 swrA S Swarming motility protein
ADEHOEND_02601 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
ADEHOEND_02602 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
ADEHOEND_02603 1.6e-123 ftsE D cell division ATP-binding protein FtsE
ADEHOEND_02604 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
ADEHOEND_02605 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
ADEHOEND_02606 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ADEHOEND_02607 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ADEHOEND_02608 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ADEHOEND_02609 5.4e-65
ADEHOEND_02610 1.9e-08 fliT S bacterial-type flagellum organization
ADEHOEND_02611 2.9e-69 fliS N flagellar protein FliS
ADEHOEND_02612 1.1e-265 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ADEHOEND_02613 6.1e-57 flaG N flagellar protein FlaG
ADEHOEND_02614 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ADEHOEND_02615 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ADEHOEND_02616 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ADEHOEND_02617 2.6e-50 yviE
ADEHOEND_02618 1.1e-156 flgL N Belongs to the bacterial flagellin family
ADEHOEND_02619 1.2e-264 flgK N flagellar hook-associated protein
ADEHOEND_02620 2.4e-78 flgN NOU FlgN protein
ADEHOEND_02621 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
ADEHOEND_02622 7e-74 yvyF S flagellar protein
ADEHOEND_02623 2.7e-129 comFC S Phosphoribosyl transferase domain
ADEHOEND_02624 5.7e-46 comFB S Late competence development protein ComFB
ADEHOEND_02625 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ADEHOEND_02626 7.3e-155 degV S protein conserved in bacteria
ADEHOEND_02627 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ADEHOEND_02628 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
ADEHOEND_02629 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
ADEHOEND_02630 6e-163 yvhJ K Transcriptional regulator
ADEHOEND_02631 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
ADEHOEND_02632 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
ADEHOEND_02633 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
ADEHOEND_02634 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
ADEHOEND_02635 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
ADEHOEND_02636 4.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ADEHOEND_02637 7.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
ADEHOEND_02638 5.3e-246 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ADEHOEND_02639 7.8e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
ADEHOEND_02640 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ADEHOEND_02641 0.0 lytB 3.5.1.28 D Stage II sporulation protein
ADEHOEND_02642 6e-38
ADEHOEND_02643 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
ADEHOEND_02644 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ADEHOEND_02645 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ADEHOEND_02646 6.5e-57
ADEHOEND_02647 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
ADEHOEND_02648 7.5e-93 ggaA M Glycosyltransferase like family 2
ADEHOEND_02649 3e-39 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ADEHOEND_02650 1.9e-54 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ADEHOEND_02651 1.9e-36 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ADEHOEND_02652 9.2e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
ADEHOEND_02653 4.1e-150 tagG GM Transport permease protein
ADEHOEND_02654 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ADEHOEND_02655 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
ADEHOEND_02656 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
ADEHOEND_02657 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
ADEHOEND_02658 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ADEHOEND_02659 3.5e-260
ADEHOEND_02660 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ADEHOEND_02661 5.7e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
ADEHOEND_02662 1.2e-261 gerBA EG Spore germination protein
ADEHOEND_02663 1.5e-192 gerBB E Spore germination protein
ADEHOEND_02664 3.2e-206 gerAC S Spore germination protein
ADEHOEND_02665 1.9e-248 ywtG EGP Major facilitator Superfamily
ADEHOEND_02666 8.4e-171 ywtF K Transcriptional regulator
ADEHOEND_02667 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
ADEHOEND_02668 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
ADEHOEND_02669 3.6e-21 ywtC
ADEHOEND_02670 1.1e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
ADEHOEND_02671 8.6e-70 pgsC S biosynthesis protein
ADEHOEND_02672 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
ADEHOEND_02673 9.3e-178 rbsR K transcriptional
ADEHOEND_02674 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADEHOEND_02675 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
ADEHOEND_02676 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
ADEHOEND_02677 2.1e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
ADEHOEND_02678 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
ADEHOEND_02679 8.7e-93 batE T Sh3 type 3 domain protein
ADEHOEND_02680 8e-48 ywsA S Protein of unknown function (DUF3892)
ADEHOEND_02681 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
ADEHOEND_02682 2.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
ADEHOEND_02683 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
ADEHOEND_02684 1.1e-169 alsR K LysR substrate binding domain
ADEHOEND_02685 4.6e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ADEHOEND_02686 7.5e-126 ywrJ
ADEHOEND_02687 2.9e-130 cotB
ADEHOEND_02688 3.5e-210 cotH M Spore Coat
ADEHOEND_02689 3.7e-12
ADEHOEND_02690 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ADEHOEND_02691 1.4e-53 S Domain of unknown function (DUF4181)
ADEHOEND_02692 1.4e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
ADEHOEND_02693 8e-82 ywrC K Transcriptional regulator
ADEHOEND_02694 1.2e-103 ywrB P Chromate transporter
ADEHOEND_02695 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
ADEHOEND_02697 1.1e-100 ywqN S NAD(P)H-dependent
ADEHOEND_02698 1.4e-161 K Transcriptional regulator
ADEHOEND_02699 3.2e-119 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
ADEHOEND_02700 3.9e-25
ADEHOEND_02701 1.9e-82 ywqJ S Pre-toxin TG
ADEHOEND_02702 5.2e-17
ADEHOEND_02703 7.9e-43
ADEHOEND_02704 7.4e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
ADEHOEND_02705 8.6e-38 ywqI S Family of unknown function (DUF5344)
ADEHOEND_02706 9.7e-23 S Domain of unknown function (DUF5082)
ADEHOEND_02707 1.4e-152 ywqG S Domain of unknown function (DUF1963)
ADEHOEND_02708 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ADEHOEND_02709 5.1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
ADEHOEND_02710 5.8e-118 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
ADEHOEND_02711 2e-116 ywqC M biosynthesis protein
ADEHOEND_02712 1.2e-17
ADEHOEND_02713 1.4e-308 ywqB S SWIM zinc finger
ADEHOEND_02714 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
ADEHOEND_02715 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
ADEHOEND_02716 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
ADEHOEND_02717 3.7e-57 ssbB L Single-stranded DNA-binding protein
ADEHOEND_02718 3.8e-66 ywpG
ADEHOEND_02719 1.1e-66 ywpF S YwpF-like protein
ADEHOEND_02720 1.2e-49 srtA 3.4.22.70 M Sortase family
ADEHOEND_02721 7e-153 ywpD T Histidine kinase
ADEHOEND_02722 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ADEHOEND_02723 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ADEHOEND_02724 8.8e-198 S aspartate phosphatase
ADEHOEND_02725 3.7e-140 flhP N flagellar basal body
ADEHOEND_02726 9.9e-125 flhO N flagellar basal body
ADEHOEND_02727 3.5e-180 mbl D Rod shape-determining protein
ADEHOEND_02728 3e-44 spoIIID K Stage III sporulation protein D
ADEHOEND_02729 2.1e-70 ywoH K COG1846 Transcriptional regulators
ADEHOEND_02730 3.9e-210 ywoG EGP Major facilitator Superfamily
ADEHOEND_02731 2.8e-231 ywoF P Right handed beta helix region
ADEHOEND_02732 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
ADEHOEND_02733 9.8e-242 ywoD EGP Major facilitator superfamily
ADEHOEND_02734 4e-104 phzA Q Isochorismatase family
ADEHOEND_02735 2.2e-76
ADEHOEND_02736 2.5e-225 amt P Ammonium transporter
ADEHOEND_02737 1.6e-58 nrgB K Belongs to the P(II) protein family
ADEHOEND_02738 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
ADEHOEND_02739 3e-72 ywnJ S VanZ like family
ADEHOEND_02740 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
ADEHOEND_02741 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
ADEHOEND_02742 8.9e-10 ywnC S Family of unknown function (DUF5362)
ADEHOEND_02743 2.2e-70 ywnF S Family of unknown function (DUF5392)
ADEHOEND_02744 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADEHOEND_02745 5e-142 mta K transcriptional
ADEHOEND_02746 2.6e-59 ywnC S Family of unknown function (DUF5362)
ADEHOEND_02747 1.6e-114 ywnB S NAD(P)H-binding
ADEHOEND_02748 1.7e-64 ywnA K Transcriptional regulator
ADEHOEND_02749 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
ADEHOEND_02750 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
ADEHOEND_02751 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
ADEHOEND_02753 3.8e-11 csbD K CsbD-like
ADEHOEND_02754 3e-84 ywmF S Peptidase M50
ADEHOEND_02755 1.3e-103 S response regulator aspartate phosphatase
ADEHOEND_02756 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADEHOEND_02757 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ADEHOEND_02759 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
ADEHOEND_02760 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
ADEHOEND_02761 1e-174 spoIID D Stage II sporulation protein D
ADEHOEND_02762 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ADEHOEND_02763 2.8e-134 ywmB S TATA-box binding
ADEHOEND_02764 1.3e-32 ywzB S membrane
ADEHOEND_02765 1.3e-60 ywmA
ADEHOEND_02766 1.4e-13 ywmA
ADEHOEND_02767 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
ADEHOEND_02768 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ADEHOEND_02769 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ADEHOEND_02770 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ADEHOEND_02771 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADEHOEND_02772 6.4e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ADEHOEND_02773 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADEHOEND_02774 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
ADEHOEND_02775 2.5e-62 atpI S ATP synthase
ADEHOEND_02776 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ADEHOEND_02777 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADEHOEND_02778 7.2e-95 ywlG S Belongs to the UPF0340 family
ADEHOEND_02779 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
ADEHOEND_02780 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADEHOEND_02781 1.7e-91 mntP P Probably functions as a manganese efflux pump
ADEHOEND_02782 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ADEHOEND_02783 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
ADEHOEND_02784 6.1e-112 spoIIR S stage II sporulation protein R
ADEHOEND_02785 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
ADEHOEND_02787 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ADEHOEND_02788 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ADEHOEND_02789 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ADEHOEND_02790 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
ADEHOEND_02791 8.6e-160 ywkB S Membrane transport protein
ADEHOEND_02792 0.0 sfcA 1.1.1.38 C malic enzyme
ADEHOEND_02793 1.6e-103 tdk 2.7.1.21 F thymidine kinase
ADEHOEND_02794 1.1e-32 rpmE J Binds the 23S rRNA
ADEHOEND_02795 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ADEHOEND_02796 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
ADEHOEND_02797 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ADEHOEND_02798 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADEHOEND_02799 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
ADEHOEND_02800 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
ADEHOEND_02801 5.1e-90 ywjG S Domain of unknown function (DUF2529)
ADEHOEND_02802 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ADEHOEND_02803 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ADEHOEND_02804 1.3e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
ADEHOEND_02805 0.0 fadF C COG0247 Fe-S oxidoreductase
ADEHOEND_02806 1.5e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
ADEHOEND_02807 3.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
ADEHOEND_02808 2.7e-42 ywjC
ADEHOEND_02809 4.8e-96 ywjB H RibD C-terminal domain
ADEHOEND_02810 0.0 ywjA V ABC transporter
ADEHOEND_02811 2.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADEHOEND_02812 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
ADEHOEND_02813 1.1e-93 narJ 1.7.5.1 C nitrate reductase
ADEHOEND_02814 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
ADEHOEND_02815 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ADEHOEND_02816 7e-86 arfM T cyclic nucleotide binding
ADEHOEND_02817 1.7e-139 ywiC S YwiC-like protein
ADEHOEND_02818 7.7e-129 fnr K helix_turn_helix, cAMP Regulatory protein
ADEHOEND_02819 2.3e-213 narK P COG2223 Nitrate nitrite transporter
ADEHOEND_02820 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
ADEHOEND_02821 4.7e-73 ywiB S protein conserved in bacteria
ADEHOEND_02822 1e-07 S Bacteriocin subtilosin A
ADEHOEND_02823 4.9e-270 C Fe-S oxidoreductases
ADEHOEND_02825 3.3e-132 cbiO V ABC transporter
ADEHOEND_02826 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
ADEHOEND_02827 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
ADEHOEND_02828 1.6e-249 L Peptidase, M16
ADEHOEND_02830 4.7e-244 ywhL CO amine dehydrogenase activity
ADEHOEND_02831 3.2e-192 ywhK CO amine dehydrogenase activity
ADEHOEND_02832 8.9e-79 S aspartate phosphatase
ADEHOEND_02834 3.7e-28 ywhH S Aminoacyl-tRNA editing domain
ADEHOEND_02835 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
ADEHOEND_02836 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ADEHOEND_02837 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ADEHOEND_02838 3.6e-49
ADEHOEND_02839 5.2e-95 ywhD S YwhD family
ADEHOEND_02840 5.1e-119 ywhC S Peptidase family M50
ADEHOEND_02841 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
ADEHOEND_02842 9.5e-71 ywhA K Transcriptional regulator
ADEHOEND_02843 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ADEHOEND_02845 9.8e-237 mmr U Major Facilitator Superfamily
ADEHOEND_02846 6.2e-79 yffB K Transcriptional regulator
ADEHOEND_02847 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
ADEHOEND_02848 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
ADEHOEND_02849 3.1e-36 ywzC S Belongs to the UPF0741 family
ADEHOEND_02850 5.1e-110 rsfA_1
ADEHOEND_02851 1.6e-155 ywfM EG EamA-like transporter family
ADEHOEND_02852 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
ADEHOEND_02853 1.1e-156 cysL K Transcriptional regulator
ADEHOEND_02854 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
ADEHOEND_02855 1.1e-146 ywfI C May function as heme-dependent peroxidase
ADEHOEND_02856 1.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
ADEHOEND_02857 5e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
ADEHOEND_02858 1.9e-209 bacE EGP Major facilitator Superfamily
ADEHOEND_02859 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
ADEHOEND_02860 2.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ADEHOEND_02861 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
ADEHOEND_02862 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
ADEHOEND_02863 6e-206 ywfA EGP Major facilitator Superfamily
ADEHOEND_02864 1.8e-232 lysP E amino acid
ADEHOEND_02865 0.0 rocB E arginine degradation protein
ADEHOEND_02866 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
ADEHOEND_02867 8.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
ADEHOEND_02868 3.4e-77
ADEHOEND_02869 1.3e-86 spsL 5.1.3.13 M Spore Coat
ADEHOEND_02870 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
ADEHOEND_02871 1.1e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ADEHOEND_02872 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ADEHOEND_02873 1.5e-183 spsG M Spore Coat
ADEHOEND_02874 1e-128 spsF M Spore Coat
ADEHOEND_02875 6e-213 spsE 2.5.1.56 M acid synthase
ADEHOEND_02876 1.7e-162 spsD 2.3.1.210 K Spore Coat
ADEHOEND_02877 1.1e-222 spsC E Belongs to the DegT DnrJ EryC1 family
ADEHOEND_02878 1.4e-267 spsB M Capsule polysaccharide biosynthesis protein
ADEHOEND_02879 4.5e-143 spsA M Spore Coat
ADEHOEND_02880 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
ADEHOEND_02881 4.3e-59 ywdK S small membrane protein
ADEHOEND_02882 3.7e-238 ywdJ F Xanthine uracil
ADEHOEND_02883 6.6e-48 ywdI S Family of unknown function (DUF5327)
ADEHOEND_02884 1e-259 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
ADEHOEND_02885 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ADEHOEND_02886 1.6e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
ADEHOEND_02887 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ADEHOEND_02888 2e-28 ywdA
ADEHOEND_02889 1.4e-283 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
ADEHOEND_02890 1.8e-251 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ADEHOEND_02891 6.7e-139 focA P Formate/nitrite transporter
ADEHOEND_02892 7e-150 sacT K transcriptional antiterminator
ADEHOEND_02894 0.0 vpr O Belongs to the peptidase S8 family
ADEHOEND_02895 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADEHOEND_02896 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
ADEHOEND_02897 8.6e-202 rodA D Belongs to the SEDS family
ADEHOEND_02898 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
ADEHOEND_02899 7.7e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
ADEHOEND_02900 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
ADEHOEND_02901 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ADEHOEND_02902 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
ADEHOEND_02903 1e-35 ywzA S membrane
ADEHOEND_02904 2.6e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
ADEHOEND_02905 1.9e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ADEHOEND_02906 9.5e-60 gtcA S GtrA-like protein
ADEHOEND_02907 1.1e-121 ywcC K transcriptional regulator
ADEHOEND_02909 9.8e-49 ywcB S Protein of unknown function, DUF485
ADEHOEND_02910 6.9e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADEHOEND_02911 4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
ADEHOEND_02912 3.2e-223 ywbN P Dyp-type peroxidase family protein
ADEHOEND_02913 2e-163 ycdO P periplasmic lipoprotein involved in iron transport
ADEHOEND_02914 9e-254 P COG0672 High-affinity Fe2 Pb2 permease
ADEHOEND_02915 4.5e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
ADEHOEND_02916 1.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ADEHOEND_02917 4.3e-153 ywbI K Transcriptional regulator
ADEHOEND_02918 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
ADEHOEND_02919 2.3e-111 ywbG M effector of murein hydrolase
ADEHOEND_02920 8.1e-208 ywbF EGP Major facilitator Superfamily
ADEHOEND_02921 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
ADEHOEND_02922 3.5e-219 ywbD 2.1.1.191 J Methyltransferase
ADEHOEND_02923 9.9e-67 ywbC 4.4.1.5 E glyoxalase
ADEHOEND_02924 6.9e-96 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ADEHOEND_02925 8.3e-125 ywbB S Protein of unknown function (DUF2711)
ADEHOEND_02926 1.4e-240 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ADEHOEND_02927 2.9e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
ADEHOEND_02928 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ADEHOEND_02929 7.6e-152 sacY K transcriptional antiterminator
ADEHOEND_02930 4.5e-168 gspA M General stress
ADEHOEND_02931 1.5e-124 ywaF S Integral membrane protein
ADEHOEND_02932 1.2e-86 ywaE K Transcriptional regulator
ADEHOEND_02933 3.9e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ADEHOEND_02934 3.7e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
ADEHOEND_02935 4e-92 K Helix-turn-helix XRE-family like proteins
ADEHOEND_02936 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
ADEHOEND_02937 8.8e-130 ynfM EGP Major facilitator Superfamily
ADEHOEND_02938 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
ADEHOEND_02939 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
ADEHOEND_02940 5e-14 S D-Ala-teichoic acid biosynthesis protein
ADEHOEND_02941 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ADEHOEND_02942 3.6e-232 dltB M membrane protein involved in D-alanine export
ADEHOEND_02943 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ADEHOEND_02944 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ADEHOEND_02945 8.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
ADEHOEND_02946 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
ADEHOEND_02947 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
ADEHOEND_02948 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
ADEHOEND_02949 7e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ADEHOEND_02950 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
ADEHOEND_02951 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
ADEHOEND_02952 1.1e-19 yxzF
ADEHOEND_02953 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
ADEHOEND_02954 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
ADEHOEND_02955 1.6e-211 yxlH EGP Major facilitator Superfamily
ADEHOEND_02956 2.6e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
ADEHOEND_02957 8.2e-165 yxlF V ABC transporter, ATP-binding protein
ADEHOEND_02958 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
ADEHOEND_02959 1.4e-30
ADEHOEND_02960 1.6e-46 yxlC S Family of unknown function (DUF5345)
ADEHOEND_02961 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
ADEHOEND_02962 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
ADEHOEND_02963 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ADEHOEND_02964 0.0 cydD V ATP-binding protein
ADEHOEND_02965 4e-309 cydD V ATP-binding
ADEHOEND_02966 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
ADEHOEND_02967 6.9e-267 cydA 1.10.3.14 C oxidase, subunit
ADEHOEND_02968 2.1e-228 cimH C COG3493 Na citrate symporter
ADEHOEND_02969 2.3e-309 3.4.24.84 O Peptidase family M48
ADEHOEND_02971 9.9e-152 yxkH G Polysaccharide deacetylase
ADEHOEND_02972 5.9e-205 msmK P Belongs to the ABC transporter superfamily
ADEHOEND_02973 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
ADEHOEND_02974 2.5e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ADEHOEND_02975 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ADEHOEND_02976 2.8e-74 yxkC S Domain of unknown function (DUF4352)
ADEHOEND_02977 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
ADEHOEND_02978 7.7e-77 S Protein of unknown function (DUF1453)
ADEHOEND_02979 1.6e-190 yxjM T Signal transduction histidine kinase
ADEHOEND_02980 9.8e-115 K helix_turn_helix, Lux Regulon
ADEHOEND_02981 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
ADEHOEND_02983 1.4e-86 yxjI S LURP-one-related
ADEHOEND_02984 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
ADEHOEND_02985 1e-220 yxjG 2.1.1.14 E Methionine synthase
ADEHOEND_02986 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
ADEHOEND_02987 3.4e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
ADEHOEND_02988 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ADEHOEND_02989 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
ADEHOEND_02990 5e-142 rlmA 2.1.1.187 Q Methyltransferase domain
ADEHOEND_02991 5.4e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ADEHOEND_02992 1.5e-102 T Domain of unknown function (DUF4163)
ADEHOEND_02993 3e-47 yxiS
ADEHOEND_02994 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
ADEHOEND_02995 6.6e-224 citH C Citrate transporter
ADEHOEND_02996 3.6e-142 exoK GH16 M licheninase activity
ADEHOEND_02997 8.3e-151 licT K transcriptional antiterminator
ADEHOEND_02998 2e-110
ADEHOEND_02999 5.6e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
ADEHOEND_03000 5.6e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
ADEHOEND_03001 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
ADEHOEND_03004 1.6e-48 yxiJ S YxiJ-like protein
ADEHOEND_03005 1.2e-96 yxiI S Protein of unknown function (DUF2716)
ADEHOEND_03006 3.8e-81
ADEHOEND_03007 4.9e-46
ADEHOEND_03008 3.7e-75 yxiG
ADEHOEND_03009 6.4e-63
ADEHOEND_03010 1.7e-84
ADEHOEND_03011 1.5e-71 yxxG
ADEHOEND_03012 0.0 wapA M COG3209 Rhs family protein
ADEHOEND_03013 2.9e-168 yxxF EG EamA-like transporter family
ADEHOEND_03014 1.1e-72 yxiE T Belongs to the universal stress protein A family
ADEHOEND_03015 6.2e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ADEHOEND_03016 4.3e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ADEHOEND_03017 3.6e-51
ADEHOEND_03018 2.2e-78 S SMI1 / KNR4 family
ADEHOEND_03019 0.0 S nuclease activity
ADEHOEND_03020 3.6e-39 yxiC S Family of unknown function (DUF5344)
ADEHOEND_03021 2.1e-21 S Domain of unknown function (DUF5082)
ADEHOEND_03022 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
ADEHOEND_03023 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
ADEHOEND_03024 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
ADEHOEND_03025 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ADEHOEND_03026 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
ADEHOEND_03027 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
ADEHOEND_03028 1.3e-249 lysP E amino acid
ADEHOEND_03029 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
ADEHOEND_03030 8.3e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ADEHOEND_03031 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ADEHOEND_03032 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
ADEHOEND_03033 1.3e-151 yxxB S Domain of Unknown Function (DUF1206)
ADEHOEND_03034 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
ADEHOEND_03035 2e-255 yxeQ S MmgE/PrpD family
ADEHOEND_03036 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
ADEHOEND_03037 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
ADEHOEND_03038 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
ADEHOEND_03039 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
ADEHOEND_03040 7.5e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ADEHOEND_03041 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADEHOEND_03043 1.2e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
ADEHOEND_03044 1.4e-150 yidA S hydrolases of the HAD superfamily
ADEHOEND_03047 1.3e-20 yxeE
ADEHOEND_03048 1.9e-16 yxeD
ADEHOEND_03049 8.5e-69
ADEHOEND_03050 1.9e-175 fhuD P ABC transporter
ADEHOEND_03051 1.5e-58 yxeA S Protein of unknown function (DUF1093)
ADEHOEND_03052 0.0 yxdM V ABC transporter (permease)
ADEHOEND_03053 9.4e-141 yxdL V ABC transporter, ATP-binding protein
ADEHOEND_03054 4.8e-182 T PhoQ Sensor
ADEHOEND_03055 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ADEHOEND_03056 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
ADEHOEND_03057 2.3e-137 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
ADEHOEND_03058 8.6e-167 iolH G Xylose isomerase-like TIM barrel
ADEHOEND_03059 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
ADEHOEND_03060 5.1e-235 iolF EGP Major facilitator Superfamily
ADEHOEND_03061 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
ADEHOEND_03062 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
ADEHOEND_03063 1.4e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
ADEHOEND_03064 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
ADEHOEND_03065 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ADEHOEND_03066 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
ADEHOEND_03067 8.3e-176 iolS C Aldo keto reductase
ADEHOEND_03069 8.3e-48 yxcD S Protein of unknown function (DUF2653)
ADEHOEND_03070 2.3e-246 csbC EGP Major facilitator Superfamily
ADEHOEND_03071 0.0 htpG O Molecular chaperone. Has ATPase activity
ADEHOEND_03073 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
ADEHOEND_03074 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
ADEHOEND_03075 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
ADEHOEND_03076 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
ADEHOEND_03077 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
ADEHOEND_03078 3.3e-166 ygxA S Nucleotidyltransferase-like
ADEHOEND_03079 1.1e-54 ygzB S UPF0295 protein
ADEHOEND_03080 4e-80 perR P Belongs to the Fur family
ADEHOEND_03081 6.3e-87 bcp 1.11.1.15 O Peroxiredoxin
ADEHOEND_03082 1.2e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
ADEHOEND_03083 8.7e-180 ygaE S Membrane
ADEHOEND_03084 1.8e-301 ygaD V ABC transporter
ADEHOEND_03085 1.3e-104 ygaC J Belongs to the UPF0374 family
ADEHOEND_03086 1.5e-37 ygaB S YgaB-like protein
ADEHOEND_03087 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
ADEHOEND_03088 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ADEHOEND_03089 6.9e-36 yfhS
ADEHOEND_03090 3.3e-210 mutY L A G-specific
ADEHOEND_03091 1.2e-185 yfhP S membrane-bound metal-dependent
ADEHOEND_03092 0.0 yfhO S Bacterial membrane protein YfhO
ADEHOEND_03093 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
ADEHOEND_03094 1.3e-170 yfhM S Alpha beta hydrolase
ADEHOEND_03095 3.5e-51 yfhL S SdpI/YhfL protein family
ADEHOEND_03096 2.4e-87 batE T Bacterial SH3 domain homologues
ADEHOEND_03097 2.9e-44 yfhJ S WVELL protein
ADEHOEND_03098 6.2e-20 sspK S reproduction
ADEHOEND_03099 1.1e-209 yfhI EGP Major facilitator Superfamily
ADEHOEND_03101 9.7e-52 yfhH S Protein of unknown function (DUF1811)
ADEHOEND_03102 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
ADEHOEND_03103 1.6e-171 yfhF S nucleoside-diphosphate sugar epimerase
ADEHOEND_03105 2.1e-25 yfhD S YfhD-like protein
ADEHOEND_03106 1.5e-106 yfhC C nitroreductase
ADEHOEND_03107 1.8e-167 yfhB 5.3.3.17 S PhzF family
ADEHOEND_03108 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEHOEND_03109 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEHOEND_03110 1e-176 yfiY P ABC transporter substrate-binding protein
ADEHOEND_03111 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ADEHOEND_03112 5.8e-80 yfiV K transcriptional
ADEHOEND_03113 3.4e-283 yfiU EGP Major facilitator Superfamily
ADEHOEND_03114 3.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
ADEHOEND_03115 1.5e-209 yfiS EGP Major facilitator Superfamily
ADEHOEND_03116 7.1e-107 yfiR K Transcriptional regulator
ADEHOEND_03117 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
ADEHOEND_03118 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
ADEHOEND_03119 8.3e-99 padR K transcriptional
ADEHOEND_03120 2.6e-203 V COG0842 ABC-type multidrug transport system, permease component
ADEHOEND_03121 2e-206 V ABC-2 family transporter protein
ADEHOEND_03122 1.4e-170 V ABC transporter, ATP-binding protein
ADEHOEND_03123 3.2e-113 KT LuxR family transcriptional regulator
ADEHOEND_03124 1.1e-214 yxjM T Histidine kinase
ADEHOEND_03126 1.1e-233 S Oxidoreductase
ADEHOEND_03127 8.4e-184 G Xylose isomerase
ADEHOEND_03128 1.8e-262 iolT EGP Major facilitator Superfamily
ADEHOEND_03129 1.5e-177 K AraC-like ligand binding domain
ADEHOEND_03130 5.7e-163 yfiE 1.13.11.2 S glyoxalase
ADEHOEND_03131 6.4e-64 mhqP S DoxX
ADEHOEND_03132 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
ADEHOEND_03133 8.4e-307 yfiB3 V ABC transporter
ADEHOEND_03134 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ADEHOEND_03135 1.6e-140 glvR K Helix-turn-helix domain, rpiR family
ADEHOEND_03136 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
ADEHOEND_03137 7.4e-44 yfjA S Belongs to the WXG100 family
ADEHOEND_03138 9.2e-191 yfjB
ADEHOEND_03139 4.5e-143 yfjC
ADEHOEND_03140 1.8e-101 yfjD S Family of unknown function (DUF5381)
ADEHOEND_03141 1.4e-79 S Family of unknown function (DUF5381)
ADEHOEND_03142 4e-56 yfjF S UPF0060 membrane protein
ADEHOEND_03143 8.3e-24 sspH S Belongs to the SspH family
ADEHOEND_03144 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
ADEHOEND_03145 2.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
ADEHOEND_03146 6.7e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ADEHOEND_03147 7.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
ADEHOEND_03148 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
ADEHOEND_03149 1.1e-83 yfjM S Psort location Cytoplasmic, score
ADEHOEND_03150 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADEHOEND_03151 1.6e-39 S YfzA-like protein
ADEHOEND_03152 4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADEHOEND_03153 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ADEHOEND_03154 1.7e-184 corA P Mediates influx of magnesium ions
ADEHOEND_03155 9.8e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
ADEHOEND_03156 1.7e-153 pdaA G deacetylase
ADEHOEND_03157 1.1e-26 yfjT
ADEHOEND_03158 5.4e-222 yfkA S YfkB-like domain
ADEHOEND_03159 6e-149 yfkC M Mechanosensitive ion channel
ADEHOEND_03160 1.2e-146 yfkD S YfkD-like protein
ADEHOEND_03161 1.8e-182 cax P COG0387 Ca2 H antiporter
ADEHOEND_03162 2.6e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
ADEHOEND_03163 5e-08
ADEHOEND_03164 4.8e-143 yihY S Belongs to the UPF0761 family
ADEHOEND_03165 1.2e-49 yfkI S gas vesicle protein
ADEHOEND_03166 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADEHOEND_03167 1.3e-28 yfkK S Belongs to the UPF0435 family
ADEHOEND_03168 6.8e-207 ydiM EGP Major facilitator Superfamily
ADEHOEND_03169 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
ADEHOEND_03170 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
ADEHOEND_03171 1.8e-124 yfkO C nitroreductase
ADEHOEND_03172 5.1e-133 treR K transcriptional
ADEHOEND_03173 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
ADEHOEND_03174 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ADEHOEND_03175 8.4e-25 yfkQ EG Spore germination protein
ADEHOEND_03176 3.1e-251 agcS_1 E Sodium alanine symporter
ADEHOEND_03177 6e-67 yhdN S Domain of unknown function (DUF1992)
ADEHOEND_03178 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
ADEHOEND_03179 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
ADEHOEND_03180 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
ADEHOEND_03181 5.3e-50 yflH S Protein of unknown function (DUF3243)
ADEHOEND_03182 4.1e-19 yflI
ADEHOEND_03183 4e-18 yflJ S Protein of unknown function (DUF2639)
ADEHOEND_03184 6.4e-122 yflK S protein conserved in bacteria
ADEHOEND_03185 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
ADEHOEND_03186 2.1e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ADEHOEND_03187 2.3e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
ADEHOEND_03188 1.9e-226 citM C Citrate transporter
ADEHOEND_03189 4.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
ADEHOEND_03190 8.9e-119 citT T response regulator
ADEHOEND_03191 1.5e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
ADEHOEND_03192 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
ADEHOEND_03193 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
ADEHOEND_03194 7.6e-58 yflT S Heat induced stress protein YflT
ADEHOEND_03195 2.9e-24 S Protein of unknown function (DUF3212)
ADEHOEND_03196 2.7e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
ADEHOEND_03197 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEHOEND_03198 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEHOEND_03199 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
ADEHOEND_03200 1.8e-187 yfmJ S N-terminal domain of oxidoreductase
ADEHOEND_03201 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
ADEHOEND_03202 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
ADEHOEND_03203 2.1e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
ADEHOEND_03204 1.5e-209 yfmO EGP Major facilitator Superfamily
ADEHOEND_03205 4e-69 yfmP K transcriptional
ADEHOEND_03206 3.4e-74 yfmQ S Uncharacterised protein from bacillus cereus group
ADEHOEND_03207 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
ADEHOEND_03208 1.1e-113 yfmS NT chemotaxis protein
ADEHOEND_03209 1.1e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ADEHOEND_03210 1.4e-240 yfnA E amino acid
ADEHOEND_03211 3.9e-133 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
ADEHOEND_03212 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
ADEHOEND_03213 3.3e-188 yfnD M Nucleotide-diphospho-sugar transferase
ADEHOEND_03214 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
ADEHOEND_03215 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
ADEHOEND_03216 1.9e-172 yfnG 4.2.1.45 M dehydratase
ADEHOEND_03217 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
ADEHOEND_03218 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
ADEHOEND_03219 3.8e-102 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
ADEHOEND_03220 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
ADEHOEND_03221 3.6e-199 yetN S Protein of unknown function (DUF3900)
ADEHOEND_03222 8.3e-31 yetM CH FAD binding domain
ADEHOEND_03223 2.6e-104 yetJ S Belongs to the BI1 family
ADEHOEND_03224 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
ADEHOEND_03225 5.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ADEHOEND_03226 2.2e-34
ADEHOEND_03227 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ADEHOEND_03228 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
ADEHOEND_03229 4e-122 yetF S membrane
ADEHOEND_03230 8.9e-256 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
ADEHOEND_03231 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
ADEHOEND_03232 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
ADEHOEND_03233 1.5e-288 lplA G Bacterial extracellular solute-binding protein
ADEHOEND_03234 0.0 yetA
ADEHOEND_03235 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
ADEHOEND_03236 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
ADEHOEND_03237 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
ADEHOEND_03238 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
ADEHOEND_03239 2.2e-111 yesV S Protein of unknown function, DUF624
ADEHOEND_03240 3e-127 yesU S Domain of unknown function (DUF1961)
ADEHOEND_03241 5.1e-130 E GDSL-like Lipase/Acylhydrolase
ADEHOEND_03242 0.0 yesS K Transcriptional regulator
ADEHOEND_03243 3.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
ADEHOEND_03244 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
ADEHOEND_03245 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
ADEHOEND_03246 1.6e-246 yesO G Bacterial extracellular solute-binding protein
ADEHOEND_03247 1.4e-201 yesN K helix_turn_helix, arabinose operon control protein
ADEHOEND_03248 0.0 yesM 2.7.13.3 T Histidine kinase
ADEHOEND_03249 1.2e-101 yesL S Protein of unknown function, DUF624
ADEHOEND_03250 1.3e-101 yesJ K Acetyltransferase (GNAT) family
ADEHOEND_03251 5.2e-104 cotJC P Spore Coat
ADEHOEND_03252 1.5e-45 cotJB S CotJB protein
ADEHOEND_03253 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
ADEHOEND_03254 5.5e-142 yesF GM NAD(P)H-binding
ADEHOEND_03255 2.5e-77 yesE S SnoaL-like domain
ADEHOEND_03256 8.5e-102 dhaR3 K Transcriptional regulator
ADEHOEND_03258 2.7e-126 yeeN K transcriptional regulatory protein
ADEHOEND_03260 1.6e-213 S Tetratricopeptide repeat
ADEHOEND_03261 1e-39
ADEHOEND_03262 4.1e-26 3.4.24.40 CO amine dehydrogenase activity
ADEHOEND_03263 2e-125 3.4.24.40 CO amine dehydrogenase activity
ADEHOEND_03264 8.7e-101 L endonuclease activity
ADEHOEND_03266 0.0 L nucleic acid phosphodiester bond hydrolysis
ADEHOEND_03267 4.2e-75 S Protein of unknown function, DUF600
ADEHOEND_03268 2.7e-27
ADEHOEND_03270 1.4e-100 S response regulator aspartate phosphatase
ADEHOEND_03272 5.8e-43
ADEHOEND_03274 0.0 L Type III restriction enzyme res subunit
ADEHOEND_03275 1.6e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADEHOEND_03276 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
ADEHOEND_03277 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADEHOEND_03278 1.3e-148 yerO K Transcriptional regulator
ADEHOEND_03279 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADEHOEND_03280 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ADEHOEND_03281 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADEHOEND_03282 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADEHOEND_03283 6.1e-123 sapB S MgtC SapB transporter
ADEHOEND_03284 2.7e-196 yerI S homoserine kinase type II (protein kinase fold)
ADEHOEND_03285 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
ADEHOEND_03286 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ADEHOEND_03287 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
ADEHOEND_03288 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ADEHOEND_03289 8.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
ADEHOEND_03290 4.8e-51 yerC S protein conserved in bacteria
ADEHOEND_03291 8.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
ADEHOEND_03292 0.0 yerA 3.5.4.2 F adenine deaminase
ADEHOEND_03293 2.7e-27 S Protein of unknown function (DUF2892)
ADEHOEND_03294 6.4e-227 yjeH E Amino acid permease
ADEHOEND_03295 3.5e-73 K helix_turn_helix ASNC type
ADEHOEND_03296 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
ADEHOEND_03297 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
ADEHOEND_03298 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ADEHOEND_03299 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
ADEHOEND_03300 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ADEHOEND_03301 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADEHOEND_03302 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADEHOEND_03303 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADEHOEND_03304 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
ADEHOEND_03305 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADEHOEND_03306 4.5e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ADEHOEND_03307 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ADEHOEND_03308 8e-28 yebG S NETI protein
ADEHOEND_03309 8.9e-93 yebE S UPF0316 protein
ADEHOEND_03311 8.3e-116 yebC M Membrane
ADEHOEND_03312 7.8e-212 pbuG S permease
ADEHOEND_03313 9.8e-256 S Domain of unknown function (DUF4179)
ADEHOEND_03314 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
ADEHOEND_03315 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
ADEHOEND_03316 0.0 yebA E COG1305 Transglutaminase-like enzymes
ADEHOEND_03317 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
ADEHOEND_03318 1.5e-175 yeaC S COG0714 MoxR-like ATPases
ADEHOEND_03319 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ADEHOEND_03320 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
ADEHOEND_03321 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
ADEHOEND_03322 3.3e-175 yeaA S Protein of unknown function (DUF4003)
ADEHOEND_03323 8.4e-156 ydjP I Alpha/beta hydrolase family
ADEHOEND_03324 1.4e-34 ydjO S Cold-inducible protein YdjO
ADEHOEND_03326 2.3e-150 ydjN U Involved in the tonB-independent uptake of proteins
ADEHOEND_03327 4.5e-64 ydjM M Lytic transglycolase
ADEHOEND_03328 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
ADEHOEND_03329 2.7e-258 iolT EGP Major facilitator Superfamily
ADEHOEND_03330 4.7e-196 S Ion transport 2 domain protein
ADEHOEND_03331 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
ADEHOEND_03332 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
ADEHOEND_03333 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ADEHOEND_03334 5.1e-114 pspA KT Phage shock protein A
ADEHOEND_03335 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
ADEHOEND_03336 7.1e-256 gutA G MFS/sugar transport protein
ADEHOEND_03337 9.4e-200 gutB 1.1.1.14 E Dehydrogenase
ADEHOEND_03338 0.0 K NB-ARC domain
ADEHOEND_03339 1.1e-08 ydjC S Abhydrolase domain containing 18
ADEHOEND_03340 4.9e-257 J LlaJI restriction endonuclease
ADEHOEND_03341 1.2e-199 V AAA domain (dynein-related subfamily)
ADEHOEND_03343 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
ADEHOEND_03344 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
ADEHOEND_03345 6.4e-66 KL Phage plasmid primase P4 family
ADEHOEND_03347 4.8e-14
ADEHOEND_03348 8.8e-32 U Preprotein translocase subunit SecB
ADEHOEND_03350 4.9e-39
ADEHOEND_03351 1.2e-27 K Helix-turn-helix domain
ADEHOEND_03353 2.8e-139 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
ADEHOEND_03355 3.9e-30 xhlB S SPP1 phage holin
ADEHOEND_03356 7.3e-27 xhlA S Haemolysin XhlA
ADEHOEND_03361 8.2e-221 S peptidoglycan catabolic process
ADEHOEND_03362 1.2e-50
ADEHOEND_03363 1.7e-139
ADEHOEND_03364 8.4e-29 S Phage tail assembly chaperone protein, TAC
ADEHOEND_03365 3e-34 S Phage tail tube protein
ADEHOEND_03366 2.3e-29 S Protein of unknown function (DUF3168)
ADEHOEND_03367 1.5e-36 S Bacteriophage HK97-gp10, putative tail-component
ADEHOEND_03368 8.2e-28 S Phage head-tail joining protein
ADEHOEND_03369 3.8e-29 S Phage gp6-like head-tail connector protein
ADEHOEND_03372 5e-141 S Phage capsid family
ADEHOEND_03373 6.8e-59 S Domain of unknown function (DUF4355)
ADEHOEND_03376 8.5e-80 S Phage Mu protein F like protein
ADEHOEND_03377 3.7e-204 S Phage portal protein, SPP1 Gp6-like
ADEHOEND_03378 1e-216 S phage terminase, large subunit
ADEHOEND_03379 1.5e-84 yqaS L DNA packaging
ADEHOEND_03382 2.7e-79 L Transposase
ADEHOEND_03391 5.3e-08 S YopX protein
ADEHOEND_03395 9.9e-25
ADEHOEND_03397 5.5e-16 yqaO S Phage-like element PBSX protein XtrA
ADEHOEND_03399 6.8e-54 S Protein of unknown function (DUF1064)
ADEHOEND_03400 1.3e-07
ADEHOEND_03401 1.7e-129 xkdC L IstB-like ATP binding protein
ADEHOEND_03402 2.7e-33 3.1.3.16 L DnaD domain protein
ADEHOEND_03403 4.9e-135 recT L RecT family
ADEHOEND_03404 1e-152 yqaJ L YqaJ-like viral recombinase domain
ADEHOEND_03409 7.8e-68
ADEHOEND_03410 4e-67 S DNA binding
ADEHOEND_03411 2.6e-33
ADEHOEND_03412 8.4e-13 K Helix-turn-helix domain
ADEHOEND_03413 1.5e-16 xre K Helix-turn-helix XRE-family like proteins
ADEHOEND_03414 1.1e-47
ADEHOEND_03415 1.8e-27 S Protein of unknown function (DUF4064)
ADEHOEND_03416 1.6e-48 xkdA E IrrE N-terminal-like domain
ADEHOEND_03417 7.5e-145 L Belongs to the 'phage' integrase family
ADEHOEND_03418 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ADEHOEND_03419 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ADEHOEND_03420 7.9e-129 ydiL S CAAX protease self-immunity
ADEHOEND_03421 2.9e-27 ydiK S Domain of unknown function (DUF4305)
ADEHOEND_03422 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADEHOEND_03423 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
ADEHOEND_03424 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ADEHOEND_03425 2.1e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
ADEHOEND_03426 0.0 ydiF S ABC transporter
ADEHOEND_03427 2e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ADEHOEND_03428 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
ADEHOEND_03429 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
ADEHOEND_03430 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
ADEHOEND_03431 1.3e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ADEHOEND_03433 7.8e-08
ADEHOEND_03434 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ADEHOEND_03435 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
ADEHOEND_03436 6.4e-139 srfAD Q thioesterase
ADEHOEND_03437 6.1e-227 EGP Major Facilitator Superfamily
ADEHOEND_03438 2.3e-88 S YcxB-like protein
ADEHOEND_03439 6.4e-160 ycxC EG EamA-like transporter family
ADEHOEND_03440 5.6e-250 ycxD K GntR family transcriptional regulator
ADEHOEND_03441 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
ADEHOEND_03442 1.7e-114 yczE S membrane
ADEHOEND_03443 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
ADEHOEND_03444 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
ADEHOEND_03445 1.3e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
ADEHOEND_03446 4.9e-162 bsdA K LysR substrate binding domain
ADEHOEND_03447 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
ADEHOEND_03448 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
ADEHOEND_03449 4e-39 bsdD 4.1.1.61 S response to toxic substance
ADEHOEND_03450 2.3e-81 yclD
ADEHOEND_03451 1.9e-158 yclE 3.4.11.5 S Alpha beta hydrolase
ADEHOEND_03452 7.3e-267 dtpT E amino acid peptide transporter
ADEHOEND_03453 5.9e-292 yclG M Pectate lyase superfamily protein
ADEHOEND_03455 1.9e-276 gerKA EG Spore germination protein
ADEHOEND_03456 8e-227 gerKC S spore germination
ADEHOEND_03457 1e-196 gerKB F Spore germination protein
ADEHOEND_03458 5.6e-121 yclH P ABC transporter
ADEHOEND_03459 1.1e-195 yclI V ABC transporter (permease) YclI
ADEHOEND_03460 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ADEHOEND_03461 5.2e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
ADEHOEND_03462 2e-70 S aspartate phosphatase
ADEHOEND_03465 5.7e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
ADEHOEND_03466 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEHOEND_03467 1.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEHOEND_03468 1.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
ADEHOEND_03469 1.4e-170 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
ADEHOEND_03470 1.4e-251 ycnB EGP Major facilitator Superfamily
ADEHOEND_03471 7.9e-152 ycnC K Transcriptional regulator
ADEHOEND_03472 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
ADEHOEND_03473 1.6e-45 ycnE S Monooxygenase
ADEHOEND_03474 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
ADEHOEND_03475 5.6e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ADEHOEND_03476 2e-244 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADEHOEND_03477 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ADEHOEND_03478 1.8e-148 glcU U Glucose uptake
ADEHOEND_03479 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ADEHOEND_03480 2.9e-100 ycnI S protein conserved in bacteria
ADEHOEND_03481 4.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
ADEHOEND_03482 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
ADEHOEND_03483 7.3e-56
ADEHOEND_03484 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
ADEHOEND_03485 4.4e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
ADEHOEND_03486 9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
ADEHOEND_03487 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
ADEHOEND_03488 4.1e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
ADEHOEND_03489 1.3e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
ADEHOEND_03490 6.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
ADEHOEND_03491 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
ADEHOEND_03493 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
ADEHOEND_03494 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
ADEHOEND_03495 2.1e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
ADEHOEND_03496 2.8e-148 ycsI S Belongs to the D-glutamate cyclase family
ADEHOEND_03497 1.2e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
ADEHOEND_03498 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
ADEHOEND_03499 1.2e-132 kipR K Transcriptional regulator
ADEHOEND_03500 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
ADEHOEND_03502 1.4e-49 yczJ S biosynthesis
ADEHOEND_03503 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
ADEHOEND_03504 2.4e-172 ydhF S Oxidoreductase
ADEHOEND_03505 0.0 mtlR K transcriptional regulator, MtlR
ADEHOEND_03506 2.1e-293 ydaB IQ acyl-CoA ligase
ADEHOEND_03507 9e-99 ydaC Q Methyltransferase domain
ADEHOEND_03508 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ADEHOEND_03509 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
ADEHOEND_03510 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
ADEHOEND_03511 6.8e-77 ydaG 1.4.3.5 S general stress protein
ADEHOEND_03512 1e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
ADEHOEND_03513 3.3e-46 ydzA EGP Major facilitator Superfamily
ADEHOEND_03514 2.5e-74 lrpC K Transcriptional regulator
ADEHOEND_03515 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADEHOEND_03516 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
ADEHOEND_03517 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
ADEHOEND_03518 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
ADEHOEND_03519 4.5e-233 ydaM M Glycosyl transferase family group 2
ADEHOEND_03520 0.0 ydaN S Bacterial cellulose synthase subunit
ADEHOEND_03521 0.0 ydaO E amino acid
ADEHOEND_03522 1.9e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
ADEHOEND_03523 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
ADEHOEND_03524 2.1e-39
ADEHOEND_03525 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
ADEHOEND_03527 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
ADEHOEND_03528 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
ADEHOEND_03530 8.9e-59 ydbB G Cupin domain
ADEHOEND_03531 3.1e-62 ydbC S Domain of unknown function (DUF4937
ADEHOEND_03532 3.5e-154 ydbD P Catalase
ADEHOEND_03533 5.1e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
ADEHOEND_03534 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
ADEHOEND_03535 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
ADEHOEND_03536 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ADEHOEND_03537 9.7e-181 ydbI S AI-2E family transporter
ADEHOEND_03538 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
ADEHOEND_03539 1.6e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
ADEHOEND_03540 2.7e-52 ydbL
ADEHOEND_03541 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
ADEHOEND_03542 1.1e-18 S Fur-regulated basic protein B
ADEHOEND_03543 2.2e-07 S Fur-regulated basic protein A
ADEHOEND_03544 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ADEHOEND_03545 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
ADEHOEND_03546 3.3e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
ADEHOEND_03547 5.3e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ADEHOEND_03548 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ADEHOEND_03549 2.1e-82 ydbS S Bacterial PH domain
ADEHOEND_03550 3.9e-260 ydbT S Membrane
ADEHOEND_03551 1.2e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
ADEHOEND_03552 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ADEHOEND_03553 5.5e-182 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
ADEHOEND_03554 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADEHOEND_03555 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
ADEHOEND_03556 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
ADEHOEND_03557 3.7e-143 rsbR T Positive regulator of sigma-B
ADEHOEND_03558 5.2e-57 rsbS T antagonist
ADEHOEND_03559 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
ADEHOEND_03560 9.3e-189 rsbU 3.1.3.3 KT phosphatase
ADEHOEND_03561 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
ADEHOEND_03562 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
ADEHOEND_03563 1.1e-136 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADEHOEND_03564 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
ADEHOEND_03565 0.0 yhgF K COG2183 Transcriptional accessory protein
ADEHOEND_03566 2.6e-82 ydcK S Belongs to the SprT family
ADEHOEND_03574 3.2e-114 yecA E amino acid
ADEHOEND_03575 4.6e-107 K Transcriptional regulator
ADEHOEND_03576 2.5e-74 rimJ2 J Acetyltransferase (GNAT) domain
ADEHOEND_03577 8.5e-45
ADEHOEND_03578 3.3e-138 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
ADEHOEND_03579 1.7e-32 K Helix-turn-helix XRE-family like proteins
ADEHOEND_03580 9.6e-40
ADEHOEND_03584 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
ADEHOEND_03585 8.7e-30 cspL K Cold shock
ADEHOEND_03586 1.5e-77 carD K Transcription factor
ADEHOEND_03587 1.3e-106 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
ADEHOEND_03588 2.2e-15 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
ADEHOEND_03589 1.4e-164 rhaS5 K AraC-like ligand binding domain
ADEHOEND_03590 3.2e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
ADEHOEND_03591 1.4e-164 ydeE K AraC family transcriptional regulator
ADEHOEND_03592 1.1e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ADEHOEND_03593 1.8e-216 ydeG EGP Major facilitator superfamily
ADEHOEND_03594 2.7e-45 ydeH
ADEHOEND_03595 2.4e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
ADEHOEND_03596 1.3e-109
ADEHOEND_03597 1.1e-31 S SNARE associated Golgi protein
ADEHOEND_03598 1.8e-14 ptsH G PTS HPr component phosphorylation site
ADEHOEND_03599 3.4e-84 K Transcriptional regulator C-terminal region
ADEHOEND_03600 2e-152 ydeK EG -transporter
ADEHOEND_03601 8.7e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ADEHOEND_03602 1.3e-72 maoC I N-terminal half of MaoC dehydratase
ADEHOEND_03603 1.8e-104 ydeN S Serine hydrolase
ADEHOEND_03604 5.7e-55 K HxlR-like helix-turn-helix
ADEHOEND_03605 6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
ADEHOEND_03606 1.8e-68 ydeP K Transcriptional regulator
ADEHOEND_03607 1.7e-110 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
ADEHOEND_03608 1.5e-185 ydeR EGP Major facilitator Superfamily
ADEHOEND_03609 2.5e-104 ydeS K Transcriptional regulator
ADEHOEND_03610 1.8e-56 arsR K transcriptional
ADEHOEND_03611 2.6e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ADEHOEND_03612 7.2e-149 ydfB J GNAT acetyltransferase
ADEHOEND_03613 1e-162 ydfC EG EamA-like transporter family
ADEHOEND_03614 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ADEHOEND_03615 3.8e-116 ydfE S Flavin reductase like domain
ADEHOEND_03616 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
ADEHOEND_03617 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADEHOEND_03619 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
ADEHOEND_03620 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ADEHOEND_03621 0.0 ydfJ S drug exporters of the RND superfamily
ADEHOEND_03622 1.9e-177 S Alpha/beta hydrolase family
ADEHOEND_03623 5.9e-118 S Protein of unknown function (DUF554)
ADEHOEND_03624 3.2e-147 K Bacterial transcription activator, effector binding domain
ADEHOEND_03625 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ADEHOEND_03626 9.6e-112 ydfN C nitroreductase
ADEHOEND_03627 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
ADEHOEND_03628 8.8e-63 mhqP S DoxX
ADEHOEND_03629 1.3e-57 traF CO Thioredoxin
ADEHOEND_03630 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
ADEHOEND_03631 6.3e-29
ADEHOEND_03633 4.4e-118 ydfR S Protein of unknown function (DUF421)
ADEHOEND_03634 5.2e-122 ydfS S Protein of unknown function (DUF421)
ADEHOEND_03635 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
ADEHOEND_03636 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
ADEHOEND_03637 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
ADEHOEND_03638 3e-94 K Bacterial regulatory proteins, tetR family
ADEHOEND_03639 1.6e-52 S DoxX-like family
ADEHOEND_03640 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
ADEHOEND_03641 5.1e-134 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
ADEHOEND_03642 2e-119 purR K helix_turn _helix lactose operon repressor
ADEHOEND_03643 1e-190 csbC EGP Major facilitator Superfamily
ADEHOEND_03644 4.4e-104 G Xylose isomerase-like TIM barrel
ADEHOEND_03645 1.7e-301 expZ S ABC transporter
ADEHOEND_03646 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
ADEHOEND_03647 2.3e-90 dinB S DinB family
ADEHOEND_03648 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
ADEHOEND_03649 0.0 ydgH S drug exporters of the RND superfamily
ADEHOEND_03650 8.8e-113 drgA C nitroreductase
ADEHOEND_03651 2.4e-69 ydgJ K Winged helix DNA-binding domain
ADEHOEND_03652 4.8e-208 tcaB EGP Major facilitator Superfamily
ADEHOEND_03653 1.6e-121 ydhB S membrane transporter protein
ADEHOEND_03654 6.5e-122 ydhC K FCD
ADEHOEND_03655 6.3e-243 ydhD M Glycosyl hydrolase
ADEHOEND_03656 2.9e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
ADEHOEND_03657 4.2e-127
ADEHOEND_03658 2.6e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
ADEHOEND_03659 8.7e-68 frataxin S Domain of unknown function (DU1801)
ADEHOEND_03661 1.5e-80 K Acetyltransferase (GNAT) domain
ADEHOEND_03662 1e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
ADEHOEND_03663 2.5e-98 ydhK M Protein of unknown function (DUF1541)
ADEHOEND_03664 4.6e-200 pbuE EGP Major facilitator Superfamily
ADEHOEND_03665 4.2e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
ADEHOEND_03666 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
ADEHOEND_03667 9.8e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ADEHOEND_03668 7.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ADEHOEND_03669 7.4e-132 ydhQ K UTRA
ADEHOEND_03670 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
ADEHOEND_03671 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
ADEHOEND_03672 9e-214 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
ADEHOEND_03673 6.1e-157 ydhU P Catalase
ADEHOEND_03676 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
ADEHOEND_03678 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
ADEHOEND_03679 2.2e-142 ybbA S Putative esterase
ADEHOEND_03680 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEHOEND_03681 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEHOEND_03682 1.4e-165 feuA P Iron-uptake system-binding protein
ADEHOEND_03683 5e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
ADEHOEND_03684 4.1e-239 ybbC 3.2.1.52 S protein conserved in bacteria
ADEHOEND_03685 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
ADEHOEND_03686 4.2e-225 yfeW 3.4.16.4 V Belongs to the UPF0214 family
ADEHOEND_03687 1.4e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ADEHOEND_03688 2.1e-149 ybbH K transcriptional
ADEHOEND_03689 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ADEHOEND_03690 7.1e-86 ybbJ J acetyltransferase
ADEHOEND_03691 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
ADEHOEND_03697 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
ADEHOEND_03698 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
ADEHOEND_03699 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ADEHOEND_03700 1.5e-224 ybbR S protein conserved in bacteria
ADEHOEND_03701 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADEHOEND_03702 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ADEHOEND_03703 1.5e-174 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ADEHOEND_03704 5.8e-120 adaA 3.2.2.21 K Transcriptional regulator
ADEHOEND_03705 1.2e-97 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADEHOEND_03706 1.8e-276 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
ADEHOEND_03707 0.0 ybcC S Belongs to the UPF0753 family
ADEHOEND_03708 4.7e-91 can 4.2.1.1 P carbonic anhydrase
ADEHOEND_03710 5.6e-46
ADEHOEND_03711 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
ADEHOEND_03712 5.1e-50 ybzH K Helix-turn-helix domain
ADEHOEND_03713 4.2e-201 ybcL EGP Major facilitator Superfamily
ADEHOEND_03715 9.1e-239 J 4Fe-4S single cluster domain
ADEHOEND_03716 1.6e-277 V CAAX protease self-immunity
ADEHOEND_03717 1.9e-135 skfE V ABC transporter
ADEHOEND_03718 4e-248 skfF S ABC transporter
ADEHOEND_03719 7.8e-91 C HEAT repeats
ADEHOEND_03720 1.1e-77 txn CO Thioredoxin-like
ADEHOEND_03721 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
ADEHOEND_03722 3.8e-122 T Transcriptional regulatory protein, C terminal
ADEHOEND_03723 1.8e-168 T His Kinase A (phospho-acceptor) domain
ADEHOEND_03725 3.9e-139 KLT Protein tyrosine kinase
ADEHOEND_03726 8.5e-151 ybdN
ADEHOEND_03727 1.5e-214 ybdO S Domain of unknown function (DUF4885)
ADEHOEND_03728 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
ADEHOEND_03729 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
ADEHOEND_03730 4.9e-30 ybxH S Family of unknown function (DUF5370)
ADEHOEND_03731 1.8e-150 ybxI 3.5.2.6 V beta-lactamase
ADEHOEND_03732 7.6e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
ADEHOEND_03733 4.9e-41 ybyB
ADEHOEND_03734 8.8e-290 ybeC E amino acid
ADEHOEND_03735 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
ADEHOEND_03736 7.3e-258 glpT G -transporter
ADEHOEND_03737 2.9e-35 S Protein of unknown function (DUF2651)
ADEHOEND_03738 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
ADEHOEND_03739 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
ADEHOEND_03741 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
ADEHOEND_03742 3.7e-160 ybfH EG EamA-like transporter family
ADEHOEND_03743 5.2e-145 msmR K AraC-like ligand binding domain
ADEHOEND_03744 2.2e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ADEHOEND_03745 2.9e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
ADEHOEND_03747 1e-167 S Alpha/beta hydrolase family
ADEHOEND_03748 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADEHOEND_03749 2.7e-85 ybfM S SNARE associated Golgi protein
ADEHOEND_03750 6.9e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
ADEHOEND_03751 2e-45 ybfN
ADEHOEND_03752 3.3e-191 yceA S Belongs to the UPF0176 family
ADEHOEND_03753 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ADEHOEND_03754 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ADEHOEND_03755 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ADEHOEND_03756 4.9e-128 K UTRA
ADEHOEND_03758 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
ADEHOEND_03759 1.4e-259 mmuP E amino acid
ADEHOEND_03760 1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
ADEHOEND_03761 2.8e-255 agcS E Sodium alanine symporter
ADEHOEND_03762 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
ADEHOEND_03763 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
ADEHOEND_03764 2.6e-169 glnL T Regulator
ADEHOEND_03765 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
ADEHOEND_03766 3.2e-270 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ADEHOEND_03767 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
ADEHOEND_03768 1.2e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
ADEHOEND_03769 2.1e-123 ycbG K FCD
ADEHOEND_03770 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
ADEHOEND_03771 8.6e-167 ycbJ S Macrolide 2'-phosphotransferase
ADEHOEND_03772 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
ADEHOEND_03773 5.4e-167 eamA1 EG spore germination
ADEHOEND_03774 8.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ADEHOEND_03775 4.2e-167 T PhoQ Sensor
ADEHOEND_03776 3.5e-166 ycbN V ABC transporter, ATP-binding protein
ADEHOEND_03777 1.8e-114 S ABC-2 family transporter protein
ADEHOEND_03778 8.2e-53 ycbP S Protein of unknown function (DUF2512)
ADEHOEND_03779 2.8e-78 sleB 3.5.1.28 M Cell wall
ADEHOEND_03780 3.6e-134 ycbR T vWA found in TerF C terminus
ADEHOEND_03781 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
ADEHOEND_03782 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
ADEHOEND_03783 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADEHOEND_03784 6.9e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ADEHOEND_03785 2.9e-199 ycbU E Selenocysteine lyase
ADEHOEND_03786 3e-225 lmrB EGP the major facilitator superfamily
ADEHOEND_03787 4.8e-102 yxaF K Transcriptional regulator
ADEHOEND_03788 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
ADEHOEND_03789 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
ADEHOEND_03790 4.9e-58 S RDD family
ADEHOEND_03791 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
ADEHOEND_03792 1.2e-156 2.7.13.3 T GHKL domain
ADEHOEND_03793 1.2e-126 lytR_2 T LytTr DNA-binding domain
ADEHOEND_03794 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
ADEHOEND_03795 2.7e-200 natB CP ABC-2 family transporter protein
ADEHOEND_03796 1.7e-22 yccK C Aldo keto reductase
ADEHOEND_03797 1e-142 yccK C Aldo keto reductase
ADEHOEND_03798 6.6e-177 ycdA S Domain of unknown function (DUF5105)
ADEHOEND_03799 4.2e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
ADEHOEND_03800 1.5e-259 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
ADEHOEND_03801 2.1e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
ADEHOEND_03802 6.1e-173 S response regulator aspartate phosphatase
ADEHOEND_03803 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
ADEHOEND_03804 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
ADEHOEND_03805 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
ADEHOEND_03806 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
ADEHOEND_03807 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
ADEHOEND_03808 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADEHOEND_03809 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
ADEHOEND_03810 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
ADEHOEND_03811 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
ADEHOEND_03812 6.3e-137 terC P Protein of unknown function (DUF475)
ADEHOEND_03813 0.0 yceG S Putative component of 'biosynthetic module'
ADEHOEND_03814 2e-192 yceH P Belongs to the TelA family
ADEHOEND_03815 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
ADEHOEND_03816 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
ADEHOEND_03817 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
ADEHOEND_03818 5.1e-229 proV 3.6.3.32 E glycine betaine
ADEHOEND_03819 1.3e-127 opuAB P glycine betaine
ADEHOEND_03820 1.5e-163 opuAC E glycine betaine
ADEHOEND_03821 1.9e-217 amhX S amidohydrolase
ADEHOEND_03822 1.1e-256 ycgA S Membrane
ADEHOEND_03823 4.1e-81 ycgB
ADEHOEND_03824 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
ADEHOEND_03825 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ADEHOEND_03826 3e-290 lctP C L-lactate permease
ADEHOEND_03827 1.8e-260 mdr EGP Major facilitator Superfamily
ADEHOEND_03828 2.9e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
ADEHOEND_03829 2e-112 ycgF E Lysine exporter protein LysE YggA
ADEHOEND_03830 7.6e-151 yqcI S YqcI/YcgG family
ADEHOEND_03831 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
ADEHOEND_03832 2.4e-112 ycgI S Domain of unknown function (DUF1989)
ADEHOEND_03833 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ADEHOEND_03834 2.5e-109 tmrB S AAA domain
ADEHOEND_03835 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ADEHOEND_03836 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
ADEHOEND_03837 1.2e-177 oxyR3 K LysR substrate binding domain
ADEHOEND_03838 9.4e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
ADEHOEND_03839 4.1e-144 ycgL S Predicted nucleotidyltransferase
ADEHOEND_03840 5.1e-170 ycgM E Proline dehydrogenase
ADEHOEND_03841 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
ADEHOEND_03842 2e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADEHOEND_03843 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
ADEHOEND_03844 9.1e-145 ycgQ S membrane
ADEHOEND_03845 9.1e-140 ycgR S permeases
ADEHOEND_03846 1.6e-157 I alpha/beta hydrolase fold
ADEHOEND_03847 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
ADEHOEND_03848 3e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
ADEHOEND_03849 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
ADEHOEND_03850 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ADEHOEND_03851 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ADEHOEND_03852 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
ADEHOEND_03853 1.4e-220 nasA P COG2223 Nitrate nitrite transporter
ADEHOEND_03854 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
ADEHOEND_03855 5.5e-109 yciB M ErfK YbiS YcfS YnhG
ADEHOEND_03856 4.6e-227 yciC S GTPases (G3E family)
ADEHOEND_03857 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
ADEHOEND_03858 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
ADEHOEND_03861 6.2e-76 yckC S membrane
ADEHOEND_03862 7.8e-52 yckD S Protein of unknown function (DUF2680)
ADEHOEND_03863 8e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ADEHOEND_03864 6.5e-69 nin S Competence protein J (ComJ)
ADEHOEND_03865 3e-70 nucA M Deoxyribonuclease NucA/NucB
ADEHOEND_03866 1.9e-186 tlpC 2.7.13.3 NT chemotaxis protein
ADEHOEND_03867 3e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
ADEHOEND_03868 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
ADEHOEND_03869 1.3e-63 hxlR K transcriptional
ADEHOEND_03870 3.3e-127 yxbB Q Met-10+ like-protein
ADEHOEND_03871 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
ADEHOEND_03872 1.1e-86 yxnB
ADEHOEND_03873 0.0 asnB 6.3.5.4 E Asparagine synthase
ADEHOEND_03874 7.6e-214 yxaM U MFS_1 like family
ADEHOEND_03875 6.8e-93 S PQQ-like domain
ADEHOEND_03876 3.5e-65 S Family of unknown function (DUF5391)
ADEHOEND_03877 1.1e-75 yxaI S membrane protein domain
ADEHOEND_03878 1.4e-228 P Protein of unknown function (DUF418)
ADEHOEND_03879 1.3e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
ADEHOEND_03880 1.2e-100 yxaF K Transcriptional regulator
ADEHOEND_03881 1.9e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ADEHOEND_03882 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
ADEHOEND_03883 5.2e-50 S LrgA family
ADEHOEND_03884 1.3e-117 yxaC M effector of murein hydrolase
ADEHOEND_03885 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
ADEHOEND_03886 1.9e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
ADEHOEND_03887 2.8e-126 gntR K transcriptional
ADEHOEND_03888 2.8e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
ADEHOEND_03889 1e-230 gntP EG COG2610 H gluconate symporter and related permeases
ADEHOEND_03890 5e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ADEHOEND_03891 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
ADEHOEND_03892 1.9e-286 ahpF O Alkyl hydroperoxide reductase
ADEHOEND_03893 5.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ADEHOEND_03894 3.4e-27 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
ADEHOEND_03895 1.9e-124 yydK K Transcriptional regulator
ADEHOEND_03896 1.6e-118 S ABC-2 family transporter protein
ADEHOEND_03897 1.6e-109 prrC P ABC transporter
ADEHOEND_03898 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
ADEHOEND_03899 1.3e-202 S SIR2-like domain
ADEHOEND_03900 1.1e-180 L DNA synthesis involved in DNA repair
ADEHOEND_03901 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ADEHOEND_03902 1.1e-09 S YyzF-like protein
ADEHOEND_03903 1.3e-67
ADEHOEND_03904 3.9e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
ADEHOEND_03906 1.7e-30 yycQ S Protein of unknown function (DUF2651)
ADEHOEND_03907 5.4e-201 yycP
ADEHOEND_03908 8.4e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ADEHOEND_03909 1.4e-83 yycN 2.3.1.128 K Acetyltransferase
ADEHOEND_03910 1.1e-187 S aspartate phosphatase
ADEHOEND_03912 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
ADEHOEND_03913 1.3e-260 rocE E amino acid
ADEHOEND_03914 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
ADEHOEND_03915 7.4e-16
ADEHOEND_03916 2.8e-94
ADEHOEND_03917 2.3e-24 S Sporulation delaying protein SdpA
ADEHOEND_03918 1.5e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
ADEHOEND_03919 1.5e-40 sdpR K transcriptional
ADEHOEND_03920 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
ADEHOEND_03921 2.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
ADEHOEND_03922 1.5e-94 K PFAM response regulator receiver
ADEHOEND_03923 2.6e-73 S Peptidase propeptide and YPEB domain
ADEHOEND_03924 5.5e-33 S Peptidase propeptide and YPEB domain
ADEHOEND_03925 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADEHOEND_03926 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
ADEHOEND_03927 1.8e-153 yycI S protein conserved in bacteria
ADEHOEND_03928 3.1e-259 yycH S protein conserved in bacteria
ADEHOEND_03929 0.0 vicK 2.7.13.3 T Histidine kinase
ADEHOEND_03930 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ADEHOEND_03935 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ADEHOEND_03936 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ADEHOEND_03937 1.2e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
ADEHOEND_03938 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
ADEHOEND_03940 1.9e-15 yycC K YycC-like protein
ADEHOEND_03941 8.4e-221 yeaN P COG2807 Cyanate permease
ADEHOEND_03942 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ADEHOEND_03943 2.2e-73 rplI J binds to the 23S rRNA
ADEHOEND_03944 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
ADEHOEND_03945 8.3e-160 yybS S membrane
ADEHOEND_03947 3.3e-83 cotF M Spore coat protein
ADEHOEND_03948 1.7e-66 ydeP3 K Transcriptional regulator
ADEHOEND_03949 8.1e-163 ppaC 3.6.1.1 C Inorganic pyrophosphatase
ADEHOEND_03950 3.6e-60
ADEHOEND_03952 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
ADEHOEND_03953 2.2e-110 K TipAS antibiotic-recognition domain
ADEHOEND_03954 4.8e-124
ADEHOEND_03955 2.9e-66 yybH S SnoaL-like domain
ADEHOEND_03956 3.5e-54 yybG S Pentapeptide repeat-containing protein
ADEHOEND_03957 2.2e-216 ynfM EGP Major facilitator Superfamily
ADEHOEND_03958 4e-164 yybE K Transcriptional regulator
ADEHOEND_03959 7.7e-79 yjcF S Acetyltransferase (GNAT) domain
ADEHOEND_03960 1.6e-74 yybC
ADEHOEND_03961 7.3e-126 S Metallo-beta-lactamase superfamily
ADEHOEND_03962 5.6e-77 yybA 2.3.1.57 K transcriptional
ADEHOEND_03963 2e-71 yjcF S Acetyltransferase (GNAT) domain
ADEHOEND_03964 5.5e-96 yyaS S Membrane
ADEHOEND_03965 1.6e-91 yyaR K Acetyltransferase (GNAT) domain
ADEHOEND_03966 1.3e-65 yyaQ S YjbR
ADEHOEND_03967 2.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
ADEHOEND_03968 6.6e-246 tetL EGP Major facilitator Superfamily
ADEHOEND_03969 2.3e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
ADEHOEND_03971 4.1e-11 S Putative amidase domain
ADEHOEND_03972 5.1e-61 yyaN K MerR HTH family regulatory protein
ADEHOEND_03973 2.8e-160 yyaM EG EamA-like transporter family
ADEHOEND_03974 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
ADEHOEND_03975 3.6e-168 yyaK S CAAX protease self-immunity
ADEHOEND_03976 2.3e-243 EGP Major facilitator superfamily
ADEHOEND_03977 1.1e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
ADEHOEND_03978 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ADEHOEND_03979 8.9e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
ADEHOEND_03980 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
ADEHOEND_03981 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ADEHOEND_03982 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ADEHOEND_03983 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
ADEHOEND_03984 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ADEHOEND_03985 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ADEHOEND_03986 2.3e-33 yyzM S protein conserved in bacteria
ADEHOEND_03987 8.1e-177 yyaD S Membrane
ADEHOEND_03988 1.6e-111 yyaC S Sporulation protein YyaC
ADEHOEND_03989 2.1e-149 spo0J K Belongs to the ParB family
ADEHOEND_03990 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
ADEHOEND_03991 9.6e-74 S Bacterial PH domain
ADEHOEND_03992 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
ADEHOEND_03993 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
ADEHOEND_03994 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ADEHOEND_03995 5.8e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ADEHOEND_03996 6.5e-108 jag S single-stranded nucleic acid binding R3H
ADEHOEND_03997 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ADEHOEND_03998 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ADEHOEND_03999 7.8e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADEHOEND_04000 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ADEHOEND_04001 2.4e-33 yaaA S S4 domain
ADEHOEND_04002 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ADEHOEND_04003 1.8e-37 yaaB S Domain of unknown function (DUF370)
ADEHOEND_04004 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADEHOEND_04005 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADEHOEND_04006 2.9e-76 ctsR K Belongs to the CtsR family
ADEHOEND_04007 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
ADEHOEND_04008 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
ADEHOEND_04009 0.0 clpC O Belongs to the ClpA ClpB family
ADEHOEND_04010 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ADEHOEND_04011 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ADEHOEND_04012 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
ADEHOEND_04013 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
ADEHOEND_04014 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
ADEHOEND_04015 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADEHOEND_04016 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
ADEHOEND_04017 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
ADEHOEND_04018 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ADEHOEND_04019 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADEHOEND_04020 1.2e-88 yacP S RNA-binding protein containing a PIN domain
ADEHOEND_04021 4.4e-115 sigH K Belongs to the sigma-70 factor family
ADEHOEND_04022 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ADEHOEND_04023 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
ADEHOEND_04024 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ADEHOEND_04025 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ADEHOEND_04026 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ADEHOEND_04027 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ADEHOEND_04028 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
ADEHOEND_04029 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADEHOEND_04030 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADEHOEND_04031 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
ADEHOEND_04032 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ADEHOEND_04033 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ADEHOEND_04034 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADEHOEND_04035 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ADEHOEND_04036 2.2e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
ADEHOEND_04037 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
ADEHOEND_04038 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ADEHOEND_04039 3e-105 rplD J Forms part of the polypeptide exit tunnel
ADEHOEND_04040 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ADEHOEND_04041 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ADEHOEND_04042 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ADEHOEND_04043 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ADEHOEND_04044 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ADEHOEND_04045 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ADEHOEND_04046 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
ADEHOEND_04047 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ADEHOEND_04048 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ADEHOEND_04049 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ADEHOEND_04050 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ADEHOEND_04051 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ADEHOEND_04052 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ADEHOEND_04053 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ADEHOEND_04054 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ADEHOEND_04055 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ADEHOEND_04056 1.9e-23 rpmD J Ribosomal protein L30
ADEHOEND_04057 1.8e-72 rplO J binds to the 23S rRNA
ADEHOEND_04058 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ADEHOEND_04059 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ADEHOEND_04060 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
ADEHOEND_04061 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ADEHOEND_04062 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
ADEHOEND_04063 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ADEHOEND_04064 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ADEHOEND_04065 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADEHOEND_04066 3.6e-58 rplQ J Ribosomal protein L17
ADEHOEND_04067 2.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADEHOEND_04068 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADEHOEND_04069 4e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADEHOEND_04070 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ADEHOEND_04071 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ADEHOEND_04072 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
ADEHOEND_04073 3.4e-143 ybaJ Q Methyltransferase domain
ADEHOEND_04074 9.7e-66 ybaK S Protein of unknown function (DUF2521)
ADEHOEND_04075 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ADEHOEND_04076 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
ADEHOEND_04077 1.2e-84 gerD
ADEHOEND_04078 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
ADEHOEND_04079 7.9e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
ADEHOEND_04080 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
ADEHOEND_04081 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADEHOEND_04082 4.1e-30 yazB K transcriptional
ADEHOEND_04083 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ADEHOEND_04084 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ADEHOEND_04085 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ADEHOEND_04086 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
ADEHOEND_04087 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
ADEHOEND_04088 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ADEHOEND_04089 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ADEHOEND_04090 4.4e-135 yacD 5.2.1.8 O peptidyl-prolyl isomerase
ADEHOEND_04091 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ADEHOEND_04092 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ADEHOEND_04093 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADEHOEND_04094 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ADEHOEND_04095 4.2e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ADEHOEND_04096 3.7e-185 KLT serine threonine protein kinase
ADEHOEND_04097 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
ADEHOEND_04098 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
ADEHOEND_04101 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
ADEHOEND_04102 1.1e-44 divIC D Septum formation initiator
ADEHOEND_04103 2.5e-107 yabQ S spore cortex biosynthesis protein
ADEHOEND_04104 1.5e-49 yabP S Sporulation protein YabP
ADEHOEND_04105 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
ADEHOEND_04106 3e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
ADEHOEND_04107 2.1e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ADEHOEND_04108 1.5e-92 spoVT K stage V sporulation protein
ADEHOEND_04109 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ADEHOEND_04110 2.4e-39 yabK S Peptide ABC transporter permease
ADEHOEND_04111 2.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ADEHOEND_04112 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ADEHOEND_04113 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ADEHOEND_04114 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ADEHOEND_04115 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
ADEHOEND_04116 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
ADEHOEND_04117 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
ADEHOEND_04118 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ADEHOEND_04119 8.3e-27 sspF S DNA topological change
ADEHOEND_04120 7.8e-39 veg S protein conserved in bacteria
ADEHOEND_04121 1.6e-136 yabG S peptidase
ADEHOEND_04122 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ADEHOEND_04123 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ADEHOEND_04124 2e-167 rpfB GH23 T protein conserved in bacteria
ADEHOEND_04125 1.2e-143 tatD L hydrolase, TatD
ADEHOEND_04126 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADEHOEND_04127 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
ADEHOEND_04128 1e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ADEHOEND_04129 2.8e-48 yazA L endonuclease containing a URI domain
ADEHOEND_04130 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
ADEHOEND_04131 4.8e-31 yabA L Involved in initiation control of chromosome replication
ADEHOEND_04132 6.1e-146 yaaT S stage 0 sporulation protein
ADEHOEND_04133 1.1e-181 holB 2.7.7.7 L DNA polymerase III
ADEHOEND_04134 1.5e-71 yaaR S protein conserved in bacteria
ADEHOEND_04135 2.2e-54 yaaQ S protein conserved in bacteria
ADEHOEND_04136 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADEHOEND_04137 2.7e-274 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
ADEHOEND_04138 1.4e-201 yaaN P Belongs to the TelA family
ADEHOEND_04139 2.4e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
ADEHOEND_04140 1.7e-30 csfB S Inhibitor of sigma-G Gin
ADEHOEND_04141 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
ADEHOEND_04142 7.9e-32 yaaL S Protein of unknown function (DUF2508)
ADEHOEND_04143 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ADEHOEND_04144 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ADEHOEND_04145 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADEHOEND_04146 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ADEHOEND_04147 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
ADEHOEND_04148 5.6e-215 yaaH M Glycoside Hydrolase Family
ADEHOEND_04149 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
ADEHOEND_04150 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
ADEHOEND_04151 1.3e-09
ADEHOEND_04152 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADEHOEND_04153 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ADEHOEND_04154 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ADEHOEND_04155 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ADEHOEND_04156 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
ADEHOEND_04157 1e-181 yaaC S YaaC-like Protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)