ORF_ID e_value Gene_name EC_number CAZy COGs Description
HMMAIMLD_00001 5.2e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMMAIMLD_00002 1.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMMAIMLD_00003 2.2e-34 yaaA S S4 domain protein YaaA
HMMAIMLD_00004 4.3e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMMAIMLD_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMMAIMLD_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMMAIMLD_00007 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HMMAIMLD_00008 6.4e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMMAIMLD_00009 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMMAIMLD_00010 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HMMAIMLD_00011 1.2e-74 rplI J Binds to the 23S rRNA
HMMAIMLD_00012 3.7e-236 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMMAIMLD_00013 2.3e-207 lmrP E Major Facilitator Superfamily
HMMAIMLD_00014 6.3e-50
HMMAIMLD_00015 4.8e-190 L Helix-turn-helix domain
HMMAIMLD_00018 6.8e-130 K response regulator
HMMAIMLD_00019 0.0 vicK 2.7.13.3 T Histidine kinase
HMMAIMLD_00020 1.1e-239 yycH S YycH protein
HMMAIMLD_00021 8e-143 yycI S YycH protein
HMMAIMLD_00022 6e-154 vicX 3.1.26.11 S domain protein
HMMAIMLD_00023 4.4e-204 htrA 3.4.21.107 O serine protease
HMMAIMLD_00024 1.5e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMMAIMLD_00025 5.7e-71 K Transcriptional regulator
HMMAIMLD_00026 3.2e-175 malR K Transcriptional regulator, LacI family
HMMAIMLD_00027 3.3e-250 malT G Major Facilitator
HMMAIMLD_00028 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HMMAIMLD_00029 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HMMAIMLD_00030 1.8e-111 ysdA CP transmembrane transport
HMMAIMLD_00031 6.2e-190 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMMAIMLD_00032 1.2e-182 D Alpha beta
HMMAIMLD_00033 7.5e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMMAIMLD_00034 1.2e-216 patA 2.6.1.1 E Aminotransferase
HMMAIMLD_00035 1e-34
HMMAIMLD_00036 0.0 clpL O associated with various cellular activities
HMMAIMLD_00037 1.8e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMMAIMLD_00038 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HMMAIMLD_00039 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HMMAIMLD_00040 1.3e-162 yvgN C Aldo keto reductase
HMMAIMLD_00041 1.4e-292 glpQ 3.1.4.46 C phosphodiesterase
HMMAIMLD_00042 1.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
HMMAIMLD_00043 1.3e-188 ybhR V ABC transporter
HMMAIMLD_00044 3e-128 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HMMAIMLD_00045 7.6e-92 K transcriptional regulator
HMMAIMLD_00046 7.4e-167 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMMAIMLD_00047 2.3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMMAIMLD_00048 1.7e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HMMAIMLD_00049 1.9e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMMAIMLD_00050 9.2e-130 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMMAIMLD_00051 1.1e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMMAIMLD_00052 1.2e-16 gntT EG gluconate transmembrane transporter activity
HMMAIMLD_00053 1.7e-98 L hmm pf00665
HMMAIMLD_00054 2.7e-86 L Helix-turn-helix domain
HMMAIMLD_00055 6.9e-47
HMMAIMLD_00056 1.9e-273 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HMMAIMLD_00057 2.5e-259 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HMMAIMLD_00058 1e-148 metQ1 P Belongs to the nlpA lipoprotein family
HMMAIMLD_00059 5.7e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMMAIMLD_00060 1.2e-97 metI P ABC transporter permease
HMMAIMLD_00061 1.6e-216 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HMMAIMLD_00062 2.6e-245 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMMAIMLD_00063 9e-84 iolS C Aldo keto reductase
HMMAIMLD_00064 1.4e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMMAIMLD_00065 1.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMMAIMLD_00066 3.5e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
HMMAIMLD_00067 4.5e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMMAIMLD_00069 2.9e-81 tlpA2 L Transposase IS200 like
HMMAIMLD_00070 7.1e-239 L transposase, IS605 OrfB family
HMMAIMLD_00071 5.7e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMMAIMLD_00072 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HMMAIMLD_00073 5.7e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMMAIMLD_00075 1.4e-189 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMMAIMLD_00077 4.7e-226 glnP P ABC transporter
HMMAIMLD_00078 9.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMMAIMLD_00079 1.4e-251 cycA E Amino acid permease
HMMAIMLD_00080 1.1e-239 L transposase, IS605 OrfB family
HMMAIMLD_00081 2.9e-81 tlpA2 L Transposase IS200 like
HMMAIMLD_00082 1.1e-225 L Transposase
HMMAIMLD_00083 7.6e-214 nupG F Nucleoside transporter
HMMAIMLD_00084 2.2e-144 rihC 3.2.2.1 F Nucleoside
HMMAIMLD_00085 1.7e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HMMAIMLD_00086 2.4e-151 noc K Belongs to the ParB family
HMMAIMLD_00087 1.2e-146 spo0J K Belongs to the ParB family
HMMAIMLD_00088 2.3e-30 yyzM S Bacterial protein of unknown function (DUF951)
HMMAIMLD_00089 7.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMMAIMLD_00090 7.2e-133 XK27_01040 S Protein of unknown function (DUF1129)
HMMAIMLD_00091 3.8e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMMAIMLD_00092 2.5e-157 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMMAIMLD_00093 5.2e-131 epsB M biosynthesis protein
HMMAIMLD_00094 2.3e-112 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HMMAIMLD_00095 1.6e-140 ywqE 3.1.3.48 GM PHP domain protein
HMMAIMLD_00096 3.3e-132 cps2D 5.1.3.2 M RmlD substrate binding domain
HMMAIMLD_00097 1.1e-92 tuaA M Bacterial sugar transferase
HMMAIMLD_00098 2.5e-70 lsgF M Glycosyl transferase family 2
HMMAIMLD_00099 8.2e-108 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_00100 2.9e-137 L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_00101 5.4e-91 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HMMAIMLD_00102 1.2e-53 GT4 M Glycosyltransferase, group 1 family protein
HMMAIMLD_00105 3.4e-65 murJ S MviN-like protein
HMMAIMLD_00107 4.7e-227 tnp L MULE transposase domain
HMMAIMLD_00109 1.1e-289 L Transposase IS66 family
HMMAIMLD_00110 4.4e-23 XK27_01125 L PFAM IS66 Orf2 family protein
HMMAIMLD_00112 7.1e-89 L Transposase
HMMAIMLD_00113 1.3e-170 L Integrase core domain
HMMAIMLD_00114 5.6e-46 L Transposase
HMMAIMLD_00115 1.2e-77 tra L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_00116 1.2e-224 L Transposase
HMMAIMLD_00117 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_00118 4.2e-228 tnp L MULE transposase domain
HMMAIMLD_00119 4.1e-152 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
HMMAIMLD_00120 1.3e-193 waaB GT4 M Glycosyl transferases group 1
HMMAIMLD_00121 4e-118 L Integrase core domain
HMMAIMLD_00122 9.1e-30 L Transposase
HMMAIMLD_00123 3.5e-144 L Transposase and inactivated derivatives
HMMAIMLD_00124 6.2e-246 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMMAIMLD_00125 7.2e-228 tnp L MULE transposase domain
HMMAIMLD_00126 1.2e-54 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HMMAIMLD_00127 1.5e-225 L Transposase
HMMAIMLD_00129 1e-122 K response regulator
HMMAIMLD_00130 1.2e-208 hpk31 2.7.13.3 T Histidine kinase
HMMAIMLD_00131 2.1e-201 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMMAIMLD_00132 6.9e-140 azlC E AzlC protein
HMMAIMLD_00133 1.2e-60 azlD S branched-chain amino acid
HMMAIMLD_00134 4.2e-166 L PFAM Integrase catalytic region
HMMAIMLD_00135 2.6e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HMMAIMLD_00136 6.8e-10 K transcriptional regulator
HMMAIMLD_00137 4e-163 K AI-2E family transporter
HMMAIMLD_00138 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HMMAIMLD_00139 1.8e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMMAIMLD_00140 2.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMMAIMLD_00141 2.8e-254 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMMAIMLD_00142 4.4e-170 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
HMMAIMLD_00143 1.4e-236 S response to antibiotic
HMMAIMLD_00144 2.5e-135 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HMMAIMLD_00145 3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMMAIMLD_00146 3.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMMAIMLD_00147 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMMAIMLD_00148 2e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMMAIMLD_00149 3.3e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HMMAIMLD_00150 5.1e-107 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMMAIMLD_00151 2.1e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HMMAIMLD_00152 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
HMMAIMLD_00153 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMMAIMLD_00154 1.1e-58 tlpA2 L Transposase IS200 like
HMMAIMLD_00155 5.4e-239 L transposase, IS605 OrfB family
HMMAIMLD_00156 7.9e-224 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HMMAIMLD_00157 3.1e-176
HMMAIMLD_00158 6.5e-47 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HMMAIMLD_00159 6.2e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HMMAIMLD_00160 0.0 copA 3.6.3.54 P P-type ATPase
HMMAIMLD_00161 1e-27 EGP Major facilitator Superfamily
HMMAIMLD_00162 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
HMMAIMLD_00163 9.8e-77
HMMAIMLD_00165 7e-37 L Helix-turn-helix domain
HMMAIMLD_00166 4.7e-29 S Domain of unknown function (DUF4767)
HMMAIMLD_00167 5.4e-44 S Tautomerase enzyme
HMMAIMLD_00168 8.2e-10 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HMMAIMLD_00170 3e-119 pnb C nitroreductase
HMMAIMLD_00171 2.9e-81 S Alpha/beta hydrolase family
HMMAIMLD_00172 1.8e-80 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMMAIMLD_00173 2.2e-39 C Aldo keto reductase
HMMAIMLD_00174 2.9e-29 C Aldo keto reductase
HMMAIMLD_00177 2.2e-25 C Aldo/keto reductase family
HMMAIMLD_00178 2.5e-90 P Cadmium resistance transporter
HMMAIMLD_00179 2.4e-80 tlpA2 L Transposase IS200 like
HMMAIMLD_00180 7.1e-239 L transposase, IS605 OrfB family
HMMAIMLD_00181 3.2e-53 4.1.1.44 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HMMAIMLD_00182 7.4e-52
HMMAIMLD_00183 9.1e-283 isdH M Iron Transport-associated domain
HMMAIMLD_00184 1.5e-93 M Iron Transport-associated domain
HMMAIMLD_00185 1.1e-148 isdE P Periplasmic binding protein
HMMAIMLD_00186 7.5e-153 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMMAIMLD_00187 5.4e-141 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
HMMAIMLD_00188 2.9e-235 kgtP EGP Sugar (and other) transporter
HMMAIMLD_00189 5.8e-20 L Transposase and inactivated derivatives IS30 family
HMMAIMLD_00190 9.2e-130 tnp L MULE transposase domain
HMMAIMLD_00191 1.1e-47 tnp L MULE transposase domain
HMMAIMLD_00193 1.1e-153 gbuA 3.6.1.1, 3.6.3.32 E glycine betaine
HMMAIMLD_00194 4.8e-98 proW E glycine betaine
HMMAIMLD_00195 1.6e-102 gbuC E glycine betaine
HMMAIMLD_00196 8.2e-48 L Transposase DDE domain group 1
HMMAIMLD_00198 1e-46
HMMAIMLD_00199 1.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
HMMAIMLD_00200 9.8e-77
HMMAIMLD_00201 7.6e-180 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMMAIMLD_00202 9.5e-37 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
HMMAIMLD_00203 9.6e-102 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
HMMAIMLD_00204 4.3e-41 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
HMMAIMLD_00207 2.9e-120 arcC 2.7.2.2 E Amino acid kinase family
HMMAIMLD_00208 1.3e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HMMAIMLD_00209 1.1e-123 C nitroreductase
HMMAIMLD_00210 4.6e-137 E GDSL-like Lipase/Acylhydrolase family
HMMAIMLD_00211 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
HMMAIMLD_00212 1.1e-80 tlpA2 L Transposase IS200 like
HMMAIMLD_00213 5.1e-237 L transposase, IS605 OrfB family
HMMAIMLD_00214 2.1e-196 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HMMAIMLD_00215 1.1e-289 L Transposase IS66 family
HMMAIMLD_00216 4.4e-23 XK27_01125 L PFAM IS66 Orf2 family protein
HMMAIMLD_00218 0.0 pepN 3.4.11.2 E aminopeptidase
HMMAIMLD_00219 7.6e-82 tlpA2 L Transposase IS200 like
HMMAIMLD_00220 5.4e-239 L transposase, IS605 OrfB family
HMMAIMLD_00221 1.2e-62 K Transcriptional regulator
HMMAIMLD_00222 1.3e-24 phaG GT1 I carboxylic ester hydrolase activity
HMMAIMLD_00223 1.8e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HMMAIMLD_00225 5.4e-239 L transposase, IS605 OrfB family
HMMAIMLD_00226 1.8e-153 metQ_4 P Belongs to the nlpA lipoprotein family
HMMAIMLD_00227 5.8e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMMAIMLD_00228 0.0 helD 3.6.4.12 L DNA helicase
HMMAIMLD_00229 6.6e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HMMAIMLD_00230 6.2e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HMMAIMLD_00231 6.5e-187
HMMAIMLD_00232 4.4e-129 cobB K SIR2 family
HMMAIMLD_00233 1.5e-211 norA EGP Major facilitator Superfamily
HMMAIMLD_00234 9.5e-163 yunF F Protein of unknown function DUF72
HMMAIMLD_00235 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMMAIMLD_00236 1.8e-147 tatD L hydrolase, TatD family
HMMAIMLD_00237 5.6e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMMAIMLD_00238 1.2e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMMAIMLD_00239 2.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMMAIMLD_00240 5.8e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
HMMAIMLD_00241 1.6e-94 fhuC P ABC transporter
HMMAIMLD_00242 3.2e-128 znuB U ABC 3 transport family
HMMAIMLD_00243 7.5e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HMMAIMLD_00244 1.3e-204 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMMAIMLD_00245 3.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMMAIMLD_00246 3e-32
HMMAIMLD_00247 4.1e-142 yxeH S hydrolase
HMMAIMLD_00248 1.5e-266 ywfO S HD domain protein
HMMAIMLD_00249 4.6e-73 ywiB S Domain of unknown function (DUF1934)
HMMAIMLD_00250 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMMAIMLD_00251 4.4e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMMAIMLD_00252 2.3e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMMAIMLD_00253 6e-41 rpmE2 J Ribosomal protein L31
HMMAIMLD_00254 4e-51 mdtG EGP Major facilitator Superfamily
HMMAIMLD_00255 1.4e-77 mdtG EGP Major facilitator Superfamily
HMMAIMLD_00256 3.8e-81 tlpA2 L Transposase IS200 like
HMMAIMLD_00257 5.4e-239 L transposase, IS605 OrfB family
HMMAIMLD_00258 4.7e-123 srtA 3.4.22.70 M sortase family
HMMAIMLD_00259 4.8e-47 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMMAIMLD_00260 8.7e-88 lemA S LemA family
HMMAIMLD_00261 5.4e-156 htpX O Belongs to the peptidase M48B family
HMMAIMLD_00262 2.1e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMMAIMLD_00263 1.9e-251 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMMAIMLD_00264 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMMAIMLD_00265 2.4e-209 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMMAIMLD_00266 1.9e-56 L Toxic component of a toxin-antitoxin (TA) module
HMMAIMLD_00267 8.1e-114 S (CBS) domain
HMMAIMLD_00268 4.8e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMMAIMLD_00269 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMMAIMLD_00270 1.6e-39 yabO J S4 domain protein
HMMAIMLD_00271 1.5e-56 divIC D Septum formation initiator
HMMAIMLD_00272 3e-87 yabR J RNA binding
HMMAIMLD_00273 3.1e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMMAIMLD_00274 4.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMMAIMLD_00275 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMMAIMLD_00276 2.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMMAIMLD_00277 7e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMMAIMLD_00278 2.8e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HMMAIMLD_00281 9.8e-77
HMMAIMLD_00284 1.2e-244 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMMAIMLD_00285 3.8e-53 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_00286 4.2e-228 tnp L MULE transposase domain
HMMAIMLD_00287 5e-280 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HMMAIMLD_00288 3.3e-133 L PFAM transposase, IS4 family protein
HMMAIMLD_00289 3.6e-14
HMMAIMLD_00290 1.1e-225 L Transposase
HMMAIMLD_00291 2.3e-134 L PFAM transposase, IS4 family protein
HMMAIMLD_00292 1e-134 L PFAM transposase, IS4 family protein
HMMAIMLD_00293 1.5e-140 L PFAM Integrase catalytic region
HMMAIMLD_00294 5.2e-134 L PFAM transposase, IS4 family protein
HMMAIMLD_00295 3.3e-124 XK26_04895
HMMAIMLD_00296 7.3e-71 tnp L MULE transposase domain
HMMAIMLD_00297 5.5e-163 D nuclear chromosome segregation
HMMAIMLD_00298 4.5e-256 dtpT U amino acid peptide transporter
HMMAIMLD_00299 4.3e-163 yjjH S Calcineurin-like phosphoesterase
HMMAIMLD_00302 1.1e-115
HMMAIMLD_00303 4.3e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HMMAIMLD_00304 1.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
HMMAIMLD_00305 6.5e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMMAIMLD_00306 2.6e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMMAIMLD_00307 0.0 yhgF K Tex-like protein N-terminal domain protein
HMMAIMLD_00308 1.3e-84 ydcK S Belongs to the SprT family
HMMAIMLD_00310 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HMMAIMLD_00311 1.8e-189 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HMMAIMLD_00312 3.8e-168 mleP2 S Sodium Bile acid symporter family
HMMAIMLD_00313 5.2e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMMAIMLD_00314 1.3e-167 I alpha/beta hydrolase fold
HMMAIMLD_00315 1.2e-263 pepC 3.4.22.40 E Peptidase C1-like family
HMMAIMLD_00316 5.3e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
HMMAIMLD_00317 1.8e-116 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMMAIMLD_00318 3.8e-81 tlpA2 L Transposase IS200 like
HMMAIMLD_00319 7.1e-239 L transposase, IS605 OrfB family
HMMAIMLD_00320 2.8e-54 HA62_12640 S GCN5-related N-acetyl-transferase
HMMAIMLD_00321 4.9e-96 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HMMAIMLD_00322 1.6e-252 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMMAIMLD_00323 4.2e-206 yacL S domain protein
HMMAIMLD_00324 6.2e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMMAIMLD_00325 8.2e-52 ywlG S Belongs to the UPF0340 family
HMMAIMLD_00326 8.6e-37 ywlG S Belongs to the UPF0340 family
HMMAIMLD_00327 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMMAIMLD_00328 5.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMMAIMLD_00329 1.5e-135 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMMAIMLD_00330 1.1e-104 sigH K Belongs to the sigma-70 factor family
HMMAIMLD_00331 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMMAIMLD_00332 2.4e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMMAIMLD_00333 4.5e-97 nusG K Participates in transcription elongation, termination and antitermination
HMMAIMLD_00334 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMMAIMLD_00335 6.7e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMMAIMLD_00336 3e-243 steT E amino acid
HMMAIMLD_00337 8.4e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMMAIMLD_00338 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMMAIMLD_00339 1.1e-272 cydA 1.10.3.14 C ubiquinol oxidase
HMMAIMLD_00340 4.1e-176 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HMMAIMLD_00341 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HMMAIMLD_00342 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HMMAIMLD_00343 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMMAIMLD_00344 2.4e-248 brnQ U Component of the transport system for branched-chain amino acids
HMMAIMLD_00345 7.3e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMMAIMLD_00346 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMMAIMLD_00347 2e-35 nrdH O Glutaredoxin
HMMAIMLD_00348 6.3e-80 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMMAIMLD_00350 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMMAIMLD_00351 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMMAIMLD_00352 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMMAIMLD_00353 2.4e-21 S Protein of unknown function (DUF2508)
HMMAIMLD_00354 3e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMMAIMLD_00355 4e-53 yaaQ S Cyclic-di-AMP receptor
HMMAIMLD_00356 1.9e-192 holB 2.7.7.7 L DNA polymerase III
HMMAIMLD_00357 1.5e-55 yabA L Involved in initiation control of chromosome replication
HMMAIMLD_00358 2.1e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMMAIMLD_00359 7.3e-146 fat 3.1.2.21 I Acyl-ACP thioesterase
HMMAIMLD_00360 1.6e-282 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HMMAIMLD_00361 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HMMAIMLD_00362 2.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HMMAIMLD_00363 1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMMAIMLD_00364 4.2e-150 KT YcbB domain
HMMAIMLD_00365 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMMAIMLD_00366 1.4e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HMMAIMLD_00367 6.9e-239 arcA 3.5.3.6 E Arginine
HMMAIMLD_00368 1.8e-259 E Arginine ornithine antiporter
HMMAIMLD_00369 1.1e-23 L Helix-turn-helix domain
HMMAIMLD_00370 3.3e-166 L PFAM Integrase catalytic region
HMMAIMLD_00371 2.7e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HMMAIMLD_00372 2.2e-215 arcT 2.6.1.1 E Aminotransferase
HMMAIMLD_00373 1.1e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HMMAIMLD_00374 1.6e-108 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HMMAIMLD_00375 1.2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMMAIMLD_00377 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMMAIMLD_00378 8.7e-75 marR K Transcriptional regulator, MarR family
HMMAIMLD_00379 2.8e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMMAIMLD_00380 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMMAIMLD_00381 1.6e-171 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HMMAIMLD_00382 3.9e-128 IQ reductase
HMMAIMLD_00383 6e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMMAIMLD_00384 1.6e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMMAIMLD_00385 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMMAIMLD_00386 6e-263 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HMMAIMLD_00387 1.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMMAIMLD_00388 6.7e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HMMAIMLD_00389 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HMMAIMLD_00390 2.2e-91 bioY S BioY family
HMMAIMLD_00391 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMMAIMLD_00392 0.0 uup S ABC transporter, ATP-binding protein
HMMAIMLD_00393 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMMAIMLD_00394 7.4e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMMAIMLD_00395 4.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMMAIMLD_00396 0.0 ydaO E amino acid
HMMAIMLD_00397 6.4e-38
HMMAIMLD_00398 9e-113 yvyE 3.4.13.9 S YigZ family
HMMAIMLD_00399 1.7e-251 comFA L Helicase C-terminal domain protein
HMMAIMLD_00400 8e-128 comFC S Competence protein
HMMAIMLD_00401 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMMAIMLD_00402 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMMAIMLD_00403 3.8e-201 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMMAIMLD_00404 4.1e-53 KT PspC domain protein
HMMAIMLD_00405 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HMMAIMLD_00406 2.7e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMMAIMLD_00407 2.1e-162 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMMAIMLD_00408 5.3e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HMMAIMLD_00409 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMMAIMLD_00410 8.9e-147 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HMMAIMLD_00411 1.1e-225 mtnE 2.6.1.83 E Aminotransferase
HMMAIMLD_00412 7.6e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMMAIMLD_00413 6.7e-77 yphH S Cupin domain
HMMAIMLD_00414 2.6e-132 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMMAIMLD_00415 2.1e-154 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HMMAIMLD_00416 9.8e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMMAIMLD_00417 8.7e-31 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_00418 1.8e-37 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_00419 3.8e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HMMAIMLD_00420 1.6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HMMAIMLD_00421 2.8e-137 cof S haloacid dehalogenase-like hydrolase
HMMAIMLD_00422 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMMAIMLD_00423 6.8e-113 yfbR S HD containing hydrolase-like enzyme
HMMAIMLD_00425 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMMAIMLD_00426 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMMAIMLD_00427 2.2e-204
HMMAIMLD_00428 2.3e-159 rapZ S Displays ATPase and GTPase activities
HMMAIMLD_00429 3.2e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HMMAIMLD_00430 1.9e-167 whiA K May be required for sporulation
HMMAIMLD_00431 2.5e-118 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HMMAIMLD_00432 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMMAIMLD_00436 3.1e-234 L Transposase
HMMAIMLD_00437 3.2e-13
HMMAIMLD_00438 1.1e-78 tspO T TspO/MBR family
HMMAIMLD_00439 2.8e-154 tnp L MULE transposase domain
HMMAIMLD_00440 4.2e-214 tra L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_00441 8.3e-24 L Plasmid pRiA4b ORF-3-like protein
HMMAIMLD_00442 1e-15
HMMAIMLD_00443 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMMAIMLD_00444 6.6e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HMMAIMLD_00445 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMMAIMLD_00446 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMMAIMLD_00447 1.5e-253 yifK E Amino acid permease
HMMAIMLD_00448 8.4e-290 clcA P chloride
HMMAIMLD_00449 4.5e-33 secG U Preprotein translocase
HMMAIMLD_00450 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMMAIMLD_00451 2.9e-84 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMMAIMLD_00452 3.2e-109 yxjI
HMMAIMLD_00453 2.8e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMMAIMLD_00454 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HMMAIMLD_00455 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HMMAIMLD_00456 2.8e-88 K Acetyltransferase (GNAT) domain
HMMAIMLD_00457 2.5e-100 dnaQ 2.7.7.7 L DNA polymerase III
HMMAIMLD_00458 5.7e-166 murB 1.3.1.98 M Cell wall formation
HMMAIMLD_00459 7.8e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMMAIMLD_00460 9.1e-116 ybbR S YbbR-like protein
HMMAIMLD_00461 1.2e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMMAIMLD_00462 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMMAIMLD_00463 3.3e-52
HMMAIMLD_00464 5.4e-211 oatA I Acyltransferase
HMMAIMLD_00465 1.5e-149 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HMMAIMLD_00466 2.4e-75 lytE M Lysin motif
HMMAIMLD_00467 9.2e-160 MA20_14895 S Conserved hypothetical protein 698
HMMAIMLD_00468 2.8e-168 K LysR substrate binding domain
HMMAIMLD_00469 1.7e-131 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMMAIMLD_00470 4.6e-149 yitS S EDD domain protein, DegV family
HMMAIMLD_00471 6.5e-90 racA K Domain of unknown function (DUF1836)
HMMAIMLD_00472 2.3e-181 yfeX P Peroxidase
HMMAIMLD_00473 9.1e-181 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HMMAIMLD_00474 2.7e-122 manY G PTS system
HMMAIMLD_00475 3e-170 manN G system, mannose fructose sorbose family IID component
HMMAIMLD_00476 1.6e-57 S Domain of unknown function (DUF956)
HMMAIMLD_00478 9.7e-132 K response regulator
HMMAIMLD_00479 1.5e-251 yclK 2.7.13.3 T Histidine kinase
HMMAIMLD_00480 1.7e-151 glcU U sugar transport
HMMAIMLD_00481 1.1e-23 L Helix-turn-helix domain
HMMAIMLD_00482 1.1e-166 L PFAM Integrase catalytic region
HMMAIMLD_00483 2.9e-80 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_00484 6.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
HMMAIMLD_00485 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HMMAIMLD_00486 2.5e-258 pgi 5.3.1.9 G Belongs to the GPI family
HMMAIMLD_00488 2.7e-70 K GNAT family
HMMAIMLD_00489 2.3e-122 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HMMAIMLD_00490 4e-161 ytbE 1.1.1.346 S Aldo keto reductase
HMMAIMLD_00491 1.7e-145 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMMAIMLD_00492 3.3e-132 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HMMAIMLD_00494 3.6e-57
HMMAIMLD_00496 2.3e-07
HMMAIMLD_00497 1.8e-78 K Winged helix DNA-binding domain
HMMAIMLD_00498 0.0 lmrA V ABC transporter, ATP-binding protein
HMMAIMLD_00499 0.0 yfiC V ABC transporter
HMMAIMLD_00500 1.6e-193 ampC V Beta-lactamase
HMMAIMLD_00501 7.8e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMMAIMLD_00502 2.8e-48
HMMAIMLD_00503 3.4e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HMMAIMLD_00504 7.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HMMAIMLD_00505 3.2e-109 tdk 2.7.1.21 F thymidine kinase
HMMAIMLD_00506 2.5e-155 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMMAIMLD_00507 2.7e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMMAIMLD_00508 2.3e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMMAIMLD_00509 1.5e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMMAIMLD_00510 1.2e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMMAIMLD_00511 1.7e-183 yibE S overlaps another CDS with the same product name
HMMAIMLD_00512 5.5e-125 yibF S overlaps another CDS with the same product name
HMMAIMLD_00513 5.4e-218 pyrP F Permease
HMMAIMLD_00514 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HMMAIMLD_00515 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMMAIMLD_00516 9.8e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMMAIMLD_00517 1.4e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMMAIMLD_00518 4.7e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMMAIMLD_00519 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMMAIMLD_00520 1.3e-252 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMMAIMLD_00521 4.4e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HMMAIMLD_00522 2.8e-29 S Protein of unknown function (DUF1146)
HMMAIMLD_00523 5.5e-220 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HMMAIMLD_00524 1.3e-182 mbl D Cell shape determining protein MreB Mrl
HMMAIMLD_00525 7.9e-32 S Protein of unknown function (DUF2969)
HMMAIMLD_00526 5.8e-222 rodA D Belongs to the SEDS family
HMMAIMLD_00528 1.4e-181 S Protein of unknown function (DUF2785)
HMMAIMLD_00529 7.7e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMMAIMLD_00530 1.1e-247 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMMAIMLD_00531 2.9e-151 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HMMAIMLD_00532 2.3e-81 usp6 T universal stress protein
HMMAIMLD_00534 5.8e-236 rarA L recombination factor protein RarA
HMMAIMLD_00535 4.5e-85 yueI S Protein of unknown function (DUF1694)
HMMAIMLD_00536 1.3e-75 4.4.1.5 E Glyoxalase
HMMAIMLD_00537 5.3e-133 S Membrane
HMMAIMLD_00538 6.7e-148 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMMAIMLD_00539 8.6e-11 S YjcQ protein
HMMAIMLD_00541 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMMAIMLD_00542 1.1e-306 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMMAIMLD_00543 2.9e-215 iscS2 2.8.1.7 E Aminotransferase class V
HMMAIMLD_00544 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMMAIMLD_00545 8.5e-211 EG GntP family permease
HMMAIMLD_00546 3e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HMMAIMLD_00547 3.2e-36 M LysM domain
HMMAIMLD_00548 1.1e-40
HMMAIMLD_00549 6.9e-30 S zinc-ribbon domain
HMMAIMLD_00553 1.6e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMMAIMLD_00554 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMMAIMLD_00555 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMMAIMLD_00556 2.5e-115 radC L DNA repair protein
HMMAIMLD_00557 1.2e-180 mreB D cell shape determining protein MreB
HMMAIMLD_00558 1.4e-145 mreC M Involved in formation and maintenance of cell shape
HMMAIMLD_00559 4.3e-92 mreD M rod shape-determining protein MreD
HMMAIMLD_00560 1.4e-108 glnP P ABC transporter permease
HMMAIMLD_00561 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMMAIMLD_00562 2.4e-161 aatB ET ABC transporter substrate-binding protein
HMMAIMLD_00563 3.3e-231 ymfF S Peptidase M16 inactive domain protein
HMMAIMLD_00564 5.8e-252 ymfH S Peptidase M16
HMMAIMLD_00565 1.8e-96 ymfM S Helix-turn-helix domain
HMMAIMLD_00566 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMMAIMLD_00567 1.9e-231 cinA 3.5.1.42 S Belongs to the CinA family
HMMAIMLD_00568 1.1e-192 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMMAIMLD_00569 8.4e-205 rny S Endoribonuclease that initiates mRNA decay
HMMAIMLD_00570 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMMAIMLD_00571 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMMAIMLD_00572 4.2e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMMAIMLD_00573 2.9e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMMAIMLD_00574 1.3e-176 2.4.2.29 F queuine tRNA-ribosyltransferase activity
HMMAIMLD_00575 5.5e-42 yajC U Preprotein translocase
HMMAIMLD_00576 2.2e-179 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HMMAIMLD_00577 8.4e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMMAIMLD_00578 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMMAIMLD_00579 1.2e-42 yrzL S Belongs to the UPF0297 family
HMMAIMLD_00580 9.6e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMMAIMLD_00581 5.4e-31 yrzB S Belongs to the UPF0473 family
HMMAIMLD_00582 1.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMMAIMLD_00583 4.7e-91 cvpA S Colicin V production protein
HMMAIMLD_00584 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMMAIMLD_00585 3.9e-53 trxA O Belongs to the thioredoxin family
HMMAIMLD_00586 2.2e-224 clcA_2 P Chloride transporter, ClC family
HMMAIMLD_00587 3.6e-94 yslB S Protein of unknown function (DUF2507)
HMMAIMLD_00588 1.2e-146 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMMAIMLD_00589 3.6e-108 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMMAIMLD_00590 1.4e-95 S Phosphoesterase
HMMAIMLD_00591 1.7e-151 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HMMAIMLD_00592 4e-156 ykuT M mechanosensitive ion channel
HMMAIMLD_00593 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMMAIMLD_00594 4.9e-70
HMMAIMLD_00595 4.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMMAIMLD_00596 2.2e-185 ccpA K catabolite control protein A
HMMAIMLD_00597 3.6e-85
HMMAIMLD_00598 3.7e-134 yebC K Transcriptional regulatory protein
HMMAIMLD_00599 5.4e-83 mltD CBM50 M PFAM NLP P60 protein
HMMAIMLD_00600 2e-131 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
HMMAIMLD_00601 1.7e-180 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
HMMAIMLD_00602 7e-178 comGA NU Type II IV secretion system protein
HMMAIMLD_00603 2.1e-159 comGB NU type II secretion system
HMMAIMLD_00604 1.1e-47 comGC U competence protein ComGC
HMMAIMLD_00605 3.8e-15 NU general secretion pathway protein
HMMAIMLD_00607 1e-14
HMMAIMLD_00609 2.5e-158 ytxK 2.1.1.72 L N-6 DNA Methylase
HMMAIMLD_00610 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMMAIMLD_00611 5.3e-110 S Calcineurin-like phosphoesterase
HMMAIMLD_00612 3.4e-97 yutD S Protein of unknown function (DUF1027)
HMMAIMLD_00613 9.5e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMMAIMLD_00614 1.3e-24 S Protein of unknown function (DUF1461)
HMMAIMLD_00615 1e-103 dedA S SNARE-like domain protein
HMMAIMLD_00616 9.8e-77
HMMAIMLD_00636 7.1e-17 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HMMAIMLD_00637 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMMAIMLD_00638 5.3e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMMAIMLD_00639 6.1e-204 coiA 3.6.4.12 S Competence protein
HMMAIMLD_00640 2.3e-113 yjbH Q Thioredoxin
HMMAIMLD_00641 6e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
HMMAIMLD_00642 1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMMAIMLD_00643 8.2e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HMMAIMLD_00644 6.1e-196 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HMMAIMLD_00645 1.5e-163 rrmA 2.1.1.187 H Methyltransferase
HMMAIMLD_00646 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMMAIMLD_00647 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HMMAIMLD_00648 1.2e-07 S Protein of unknown function (DUF4044)
HMMAIMLD_00649 5.8e-58
HMMAIMLD_00650 2.8e-78 mraZ K Belongs to the MraZ family
HMMAIMLD_00651 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMMAIMLD_00652 3.5e-08 ftsL D Cell division protein FtsL
HMMAIMLD_00653 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HMMAIMLD_00654 1.2e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMMAIMLD_00655 1e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMMAIMLD_00656 6.8e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMMAIMLD_00657 8.4e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMMAIMLD_00658 3.2e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMMAIMLD_00659 9e-221 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMMAIMLD_00660 6e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMMAIMLD_00661 6.8e-41 yggT S YGGT family
HMMAIMLD_00662 1.3e-145 ylmH S S4 domain protein
HMMAIMLD_00663 4.8e-112 divIVA D DivIVA domain protein
HMMAIMLD_00665 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMMAIMLD_00666 1.2e-32 cspB K Cold shock protein
HMMAIMLD_00667 2.7e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HMMAIMLD_00669 3.9e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMMAIMLD_00670 3.4e-58 XK27_04120 S Putative amino acid metabolism
HMMAIMLD_00671 2.9e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMMAIMLD_00672 2e-194 S amidohydrolase
HMMAIMLD_00673 3e-93 S amidohydrolase
HMMAIMLD_00674 4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HMMAIMLD_00675 4.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HMMAIMLD_00676 7.1e-124 S Repeat protein
HMMAIMLD_00677 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMMAIMLD_00678 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMMAIMLD_00679 4.2e-74 spx4 1.20.4.1 P ArsC family
HMMAIMLD_00680 9e-189 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HMMAIMLD_00681 2.2e-31 ykzG S Belongs to the UPF0356 family
HMMAIMLD_00682 1.5e-74
HMMAIMLD_00683 7.5e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMMAIMLD_00684 2.4e-49 yktA S Belongs to the UPF0223 family
HMMAIMLD_00685 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HMMAIMLD_00686 0.0 typA T GTP-binding protein TypA
HMMAIMLD_00687 2.8e-216 ftsW D Belongs to the SEDS family
HMMAIMLD_00688 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HMMAIMLD_00689 1.3e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HMMAIMLD_00690 2.8e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMMAIMLD_00691 4.3e-197 ylbL T Belongs to the peptidase S16 family
HMMAIMLD_00692 1.3e-90 comEA L Competence protein ComEA
HMMAIMLD_00693 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
HMMAIMLD_00694 0.0 comEC S Competence protein ComEC
HMMAIMLD_00695 1.8e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
HMMAIMLD_00696 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
HMMAIMLD_00697 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMMAIMLD_00698 1.5e-261 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HMMAIMLD_00699 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMMAIMLD_00700 1.2e-163 S Tetratricopeptide repeat
HMMAIMLD_00701 4.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMMAIMLD_00702 5.7e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMMAIMLD_00703 1.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMMAIMLD_00704 2.8e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HMMAIMLD_00705 9.2e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HMMAIMLD_00707 3.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMMAIMLD_00708 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMMAIMLD_00709 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMMAIMLD_00710 8.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMMAIMLD_00711 1.9e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMMAIMLD_00712 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HMMAIMLD_00713 2.4e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMMAIMLD_00714 5.6e-62 S Domain of unknown function (DUF4440)
HMMAIMLD_00715 8.6e-187 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMMAIMLD_00716 7.3e-152 tesE Q hydratase
HMMAIMLD_00717 2.9e-81 tlpA2 L Transposase IS200 like
HMMAIMLD_00718 7.1e-239 L transposase, IS605 OrfB family
HMMAIMLD_00719 6.8e-98 ywrO S Flavodoxin-like fold
HMMAIMLD_00720 4.6e-45 S Protein conserved in bacteria
HMMAIMLD_00721 3e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HMMAIMLD_00722 1.1e-50 S Sugar efflux transporter for intercellular exchange
HMMAIMLD_00723 3.4e-17 xre K Helix-turn-helix domain
HMMAIMLD_00724 1.8e-198 gldA 1.1.1.6 C dehydrogenase
HMMAIMLD_00725 4.7e-171 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_00726 2.2e-92 arsB 1.20.4.1 P Sodium Bile acid symporter family
HMMAIMLD_00727 6e-104 tra L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_00728 1.4e-69 yfeO P Voltage gated chloride channel
HMMAIMLD_00729 1.1e-228 tnp L MULE transposase domain
HMMAIMLD_00730 3e-170 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_00731 5.2e-134 L PFAM transposase, IS4 family protein
HMMAIMLD_00734 5.1e-188 EGP Major facilitator Superfamily
HMMAIMLD_00736 0.0 asnB 6.3.5.4 E Aluminium induced protein
HMMAIMLD_00738 4.1e-12 S CHY zinc finger
HMMAIMLD_00740 1.1e-06 M domain protein
HMMAIMLD_00741 3.4e-18 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HMMAIMLD_00742 1.5e-13
HMMAIMLD_00743 6.7e-184 scrR3 K Transcriptional regulator, LacI family
HMMAIMLD_00744 1.3e-78 F Nucleoside 2-deoxyribosyltransferase
HMMAIMLD_00745 2.1e-90
HMMAIMLD_00747 6e-194 L Belongs to the 'phage' integrase family
HMMAIMLD_00748 8.9e-63
HMMAIMLD_00750 8.3e-07 tlpA2 L Transposase IS200 like
HMMAIMLD_00751 5.6e-247 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMMAIMLD_00752 8.5e-173 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_00753 3.7e-301 ybeC E amino acid
HMMAIMLD_00754 8.5e-173 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_00755 7.3e-98 K Bacterial regulatory proteins, tetR family
HMMAIMLD_00756 1e-51 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HMMAIMLD_00757 4e-65
HMMAIMLD_00758 1.4e-53
HMMAIMLD_00759 9.8e-217 S Domain of unknown function (DUF389)
HMMAIMLD_00760 1.5e-234 yagE E Amino acid permease
HMMAIMLD_00761 4.3e-129 tnp L DDE domain
HMMAIMLD_00762 1.3e-254 G Major Facilitator Superfamily
HMMAIMLD_00763 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HMMAIMLD_00765 8.2e-166 V Type II restriction enzyme, methylase subunits
HMMAIMLD_00766 1.9e-46 L Transposase
HMMAIMLD_00767 3.4e-171 L Integrase core domain
HMMAIMLD_00768 2e-139 V Type II restriction enzyme, methylase subunits
HMMAIMLD_00770 1.2e-15 tnp L MULE transposase domain
HMMAIMLD_00771 4.5e-44 S SEFIR domain
HMMAIMLD_00772 1.1e-289 L Transposase IS66 family
HMMAIMLD_00773 4.4e-23 XK27_01125 L PFAM IS66 Orf2 family protein
HMMAIMLD_00775 4.5e-103 tnpR L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HMMAIMLD_00776 4.3e-194 L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_00777 9.1e-76 S Short repeat of unknown function (DUF308)
HMMAIMLD_00780 4.8e-64 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HMMAIMLD_00781 2.9e-109 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HMMAIMLD_00782 2.7e-25 yitW S Iron-sulfur cluster assembly protein
HMMAIMLD_00783 5.8e-44 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HMMAIMLD_00785 6.5e-58 UW LPXTG-motif cell wall anchor domain protein
HMMAIMLD_00786 5.3e-43 UW LPXTG-motif cell wall anchor domain protein
HMMAIMLD_00787 4.1e-85 yrjD S LUD domain
HMMAIMLD_00788 3.1e-244 lutB C 4Fe-4S dicluster domain
HMMAIMLD_00789 2.1e-121 lutA C Cysteine-rich domain
HMMAIMLD_00790 1.1e-214 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HMMAIMLD_00791 7.2e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMMAIMLD_00792 4.1e-37 ynzC S UPF0291 protein
HMMAIMLD_00793 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
HMMAIMLD_00794 3.3e-115 plsC 2.3.1.51 I Acyltransferase
HMMAIMLD_00795 1.2e-135 yabB 2.1.1.223 L Methyltransferase small domain
HMMAIMLD_00796 8.7e-47 yazA L GIY-YIG catalytic domain protein
HMMAIMLD_00797 1.5e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
HMMAIMLD_00798 3.2e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMMAIMLD_00799 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HMMAIMLD_00800 4.1e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMMAIMLD_00801 5.9e-143 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMMAIMLD_00802 2.3e-134 cdsA 2.7.7.41 I Belongs to the CDS family
HMMAIMLD_00803 4.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HMMAIMLD_00804 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMMAIMLD_00805 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMMAIMLD_00806 8.3e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine
HMMAIMLD_00807 8e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HMMAIMLD_00808 2.5e-200 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMMAIMLD_00809 1.5e-188 L Helix-turn-helix domain
HMMAIMLD_00811 9.4e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMMAIMLD_00812 2.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMMAIMLD_00813 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HMMAIMLD_00814 3.3e-83 rimP J Required for maturation of 30S ribosomal subunits
HMMAIMLD_00815 3.7e-224 nusA K Participates in both transcription termination and antitermination
HMMAIMLD_00816 1.4e-47 ylxR K Protein of unknown function (DUF448)
HMMAIMLD_00817 3.2e-50 ylxQ J ribosomal protein
HMMAIMLD_00818 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMMAIMLD_00819 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMMAIMLD_00820 5.7e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMMAIMLD_00821 6e-185 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HMMAIMLD_00822 2.2e-249 EGP Major facilitator Superfamily
HMMAIMLD_00823 1.8e-58 L Helix-turn-helix domain
HMMAIMLD_00824 7.9e-18 L hmm pf00665
HMMAIMLD_00825 8.8e-119 L hmm pf00665
HMMAIMLD_00826 1.1e-253 G Major Facilitator
HMMAIMLD_00827 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HMMAIMLD_00828 3.2e-178 K Transcriptional regulator, LacI family
HMMAIMLD_00829 3.7e-158 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HMMAIMLD_00830 1.7e-08
HMMAIMLD_00831 2.7e-224 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HMMAIMLD_00833 1.1e-228 tnp L MULE transposase domain
HMMAIMLD_00834 2.9e-170 L Integrase core domain
HMMAIMLD_00835 7.5e-188 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMMAIMLD_00836 8.2e-24 ypaA S Protein of unknown function (DUF1304)
HMMAIMLD_00837 1.1e-96 D Alpha beta
HMMAIMLD_00838 1.7e-254 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HMMAIMLD_00839 2.7e-239 cycA E Amino acid permease
HMMAIMLD_00840 1.9e-46 L Transposase
HMMAIMLD_00841 1.3e-170 L Integrase core domain
HMMAIMLD_00842 2e-61
HMMAIMLD_00843 5.4e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMMAIMLD_00844 1.9e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMMAIMLD_00845 0.0 dnaK O Heat shock 70 kDa protein
HMMAIMLD_00846 5.5e-177 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMMAIMLD_00847 1.2e-94 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMMAIMLD_00848 1.6e-08 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMMAIMLD_00849 1.9e-50 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMMAIMLD_00850 5.7e-168 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
HMMAIMLD_00851 5.4e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HMMAIMLD_00852 2.9e-108 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HMMAIMLD_00853 4.4e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMMAIMLD_00854 1.9e-101 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HMMAIMLD_00855 1.2e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMMAIMLD_00856 4.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMMAIMLD_00857 7.3e-141 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMMAIMLD_00858 4.2e-55 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMMAIMLD_00859 9.9e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HMMAIMLD_00860 9.6e-200 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMMAIMLD_00861 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMMAIMLD_00862 3.9e-134 L PFAM transposase, IS4 family protein
HMMAIMLD_00863 3.3e-09
HMMAIMLD_00864 1.9e-112 3.1.3.73 G phosphoglycerate mutase
HMMAIMLD_00865 7.3e-09 C Aldo/keto reductase family
HMMAIMLD_00866 5e-84 C aldo keto reductase
HMMAIMLD_00867 1.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMMAIMLD_00868 4.8e-221 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMMAIMLD_00869 1.7e-267 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HMMAIMLD_00870 7.9e-79 K 2 iron, 2 sulfur cluster binding
HMMAIMLD_00871 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HMMAIMLD_00872 1e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HMMAIMLD_00873 4.5e-106 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HMMAIMLD_00874 5.9e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HMMAIMLD_00875 6.7e-35 C Flavodoxin
HMMAIMLD_00876 1.1e-155 L hmm pf00665
HMMAIMLD_00877 1.6e-55 L Helix-turn-helix domain
HMMAIMLD_00878 1.2e-213 tra L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_00879 1.4e-21 tlpA2 L Transposase IS200 like
HMMAIMLD_00880 1.5e-144 L transposase, IS605 OrfB family
HMMAIMLD_00881 6.8e-52 L transposase, IS605 OrfB family
HMMAIMLD_00882 2.2e-22 T His Kinase A (phosphoacceptor) domain
HMMAIMLD_00883 7.7e-188 L Helix-turn-helix domain
HMMAIMLD_00884 1.8e-220 iscS 2.8.1.7 E Aminotransferase class V
HMMAIMLD_00886 2.9e-81 tlpA2 L Transposase IS200 like
HMMAIMLD_00887 3.9e-237 L transposase, IS605 OrfB family
HMMAIMLD_00888 2e-101 P Cadmium resistance transporter
HMMAIMLD_00889 3.2e-116 S Protein of unknown function (DUF554)
HMMAIMLD_00890 8.4e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMMAIMLD_00891 5.5e-158 P Belongs to the nlpA lipoprotein family
HMMAIMLD_00892 3.9e-98 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMMAIMLD_00893 8.2e-13 L Cupin 2, conserved barrel domain protein
HMMAIMLD_00895 2e-160 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HMMAIMLD_00896 4.1e-71 K LysR substrate binding domain
HMMAIMLD_00897 1.3e-191 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HMMAIMLD_00898 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
HMMAIMLD_00899 7.4e-216 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HMMAIMLD_00900 5.9e-39 V CAAX protease self-immunity
HMMAIMLD_00901 1.2e-68 psiE S Phosphate-starvation-inducible E
HMMAIMLD_00902 1.5e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMMAIMLD_00903 1.5e-112 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HMMAIMLD_00904 7.2e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMMAIMLD_00905 9.6e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMMAIMLD_00906 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMMAIMLD_00907 1.1e-90 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HMMAIMLD_00908 6.9e-99 2.1.1.72, 3.1.21.4 L restriction endonuclease
HMMAIMLD_00909 0.0 L Type III restriction enzyme, res subunit
HMMAIMLD_00910 3.2e-254 S Protein of unknown function DUF262
HMMAIMLD_00911 7e-153 tnp L MULE transposase domain
HMMAIMLD_00912 1.4e-58 L Helix-turn-helix domain
HMMAIMLD_00913 6.5e-16 L hmm pf00665
HMMAIMLD_00914 8.8e-119 L hmm pf00665
HMMAIMLD_00915 5.2e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMMAIMLD_00917 1e-53
HMMAIMLD_00918 2.9e-176 prmA J Ribosomal protein L11 methyltransferase
HMMAIMLD_00919 2e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMMAIMLD_00920 1.3e-57
HMMAIMLD_00921 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMMAIMLD_00922 7.1e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMMAIMLD_00923 1.1e-83 slyA K Transcriptional regulator
HMMAIMLD_00924 4.6e-219 metC1 2.5.1.48, 4.4.1.8 E cystathionine
HMMAIMLD_00925 3.3e-211 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HMMAIMLD_00927 2.1e-112 papP P ABC transporter, permease protein
HMMAIMLD_00928 5.7e-94 P ABC transporter permease
HMMAIMLD_00929 1.1e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMMAIMLD_00930 6.9e-153 cjaA ET ABC transporter substrate-binding protein
HMMAIMLD_00931 4.3e-178 hom1 1.1.1.3 E Homoserine dehydrogenase
HMMAIMLD_00932 2.9e-81 tlpA2 L Transposase IS200 like
HMMAIMLD_00933 7.1e-239 L transposase, IS605 OrfB family
HMMAIMLD_00934 1.5e-12 hom1 1.1.1.3 E Homoserine dehydrogenase
HMMAIMLD_00935 5.9e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HMMAIMLD_00936 1e-246 mmuP E amino acid
HMMAIMLD_00937 4.5e-76 L Transposase DDE domain
HMMAIMLD_00938 4.8e-66 L Putative transposase of IS4/5 family (DUF4096)
HMMAIMLD_00939 5.9e-166 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HMMAIMLD_00940 2.3e-43 yniA G Phosphotransferase enzyme family
HMMAIMLD_00941 6.9e-92 yniA G Phosphotransferase enzyme family
HMMAIMLD_00942 1.2e-172 lytH 3.5.1.28 M Ami_3
HMMAIMLD_00943 8.8e-195 6.3.1.20 H Lipoate-protein ligase
HMMAIMLD_00944 8.7e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
HMMAIMLD_00945 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMMAIMLD_00946 3.3e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HMMAIMLD_00947 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HMMAIMLD_00948 8.6e-70 yqeY S YqeY-like protein
HMMAIMLD_00949 2.9e-179 phoH T phosphate starvation-inducible protein PhoH
HMMAIMLD_00950 1.1e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMMAIMLD_00951 1e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HMMAIMLD_00952 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMMAIMLD_00953 1.1e-155 recO L Involved in DNA repair and RecF pathway recombination
HMMAIMLD_00954 1.1e-186 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HMMAIMLD_00955 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HMMAIMLD_00956 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMMAIMLD_00957 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMMAIMLD_00958 6.5e-75 L COG2801 Transposase and inactivated derivatives
HMMAIMLD_00959 1.1e-225 L Transposase
HMMAIMLD_00960 1.4e-72 L Integrase core domain
HMMAIMLD_00961 3.7e-38 L Transposase and inactivated derivatives
HMMAIMLD_00962 2.5e-87
HMMAIMLD_00963 3.1e-21 S Small integral membrane protein (DUF2273)
HMMAIMLD_00964 1e-69 S Asp23 family, cell envelope-related function
HMMAIMLD_00965 6e-12 S Transglycosylase associated protein
HMMAIMLD_00966 3.8e-16
HMMAIMLD_00967 2.3e-245 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMMAIMLD_00968 3.3e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMMAIMLD_00969 5.1e-179 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMMAIMLD_00970 7.7e-263 lysC 2.7.2.4 E Belongs to the aspartokinase family
HMMAIMLD_00971 5.9e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMMAIMLD_00972 8.6e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMMAIMLD_00973 1.8e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMMAIMLD_00974 9.2e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMMAIMLD_00975 2.8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMMAIMLD_00976 5e-218 patA 2.6.1.1 E Aminotransferase
HMMAIMLD_00977 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMMAIMLD_00978 6.7e-227 ktrB P Potassium uptake protein
HMMAIMLD_00979 4.4e-118 ktrA P domain protein
HMMAIMLD_00980 1.7e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
HMMAIMLD_00981 6.5e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMMAIMLD_00982 1.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMMAIMLD_00984 0.0 dnaE 2.7.7.7 L DNA polymerase
HMMAIMLD_00985 8.3e-268 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HMMAIMLD_00986 1.6e-168 cvfB S S1 domain
HMMAIMLD_00987 5.3e-132 xerD D recombinase XerD
HMMAIMLD_00988 5.3e-68 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMMAIMLD_00989 6.6e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMMAIMLD_00990 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMMAIMLD_00991 2.8e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMMAIMLD_00992 3.7e-81 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMMAIMLD_00993 6e-199 ypbB 5.1.3.1 S Helix-turn-helix domain
HMMAIMLD_00994 3.1e-278 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HMMAIMLD_00995 9.7e-31 M Lysin motif
HMMAIMLD_00996 5.8e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMMAIMLD_00997 5.8e-209 rpsA 1.17.7.4 J Ribosomal protein S1
HMMAIMLD_00998 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMMAIMLD_00999 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMMAIMLD_01000 1.8e-234 S Tetratricopeptide repeat protein
HMMAIMLD_01001 4.7e-165 xerD L Phage integrase, N-terminal SAM-like domain
HMMAIMLD_01002 3.8e-221 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMMAIMLD_01003 0.0 yfmR S ABC transporter, ATP-binding protein
HMMAIMLD_01004 2.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMMAIMLD_01005 8.7e-95 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMMAIMLD_01006 1.2e-109 hlyIII S protein, hemolysin III
HMMAIMLD_01007 2.6e-152 DegV S EDD domain protein, DegV family
HMMAIMLD_01008 3.5e-219 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
HMMAIMLD_01009 2.2e-108 cat S Bacterial transferase hexapeptide (six repeats)
HMMAIMLD_01010 1.1e-167 ypmR E lipolytic protein G-D-S-L family
HMMAIMLD_01011 7.1e-104 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HMMAIMLD_01012 3.1e-36 yozE S Belongs to the UPF0346 family
HMMAIMLD_01013 1.2e-166 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_01014 7.9e-66 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HMMAIMLD_01015 2.3e-51 arsD S Arsenical resistance operon trans-acting repressor ArsD
HMMAIMLD_01016 1.1e-228 tnp L MULE transposase domain
HMMAIMLD_01017 0.0 arsA 3.6.3.16 D Anion-transporting ATPase
HMMAIMLD_01018 5.6e-231 arsB U Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HMMAIMLD_01019 5e-51
HMMAIMLD_01020 1.1e-225 L Transposase
HMMAIMLD_01021 3.9e-134 L PFAM transposase, IS4 family protein
HMMAIMLD_01022 3.3e-261 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HMMAIMLD_01023 1.1e-228 tnp L MULE transposase domain
HMMAIMLD_01024 3.2e-62 K Transcriptional regulator
HMMAIMLD_01025 3.4e-101 cadD P Cadmium resistance transporter
HMMAIMLD_01026 2.5e-128 L PFAM transposase, IS4 family protein
HMMAIMLD_01027 8.2e-20 K Cro/C1-type HTH DNA-binding domain
HMMAIMLD_01028 9.2e-36 K Replication initiation factor
HMMAIMLD_01029 5.2e-134 L PFAM transposase, IS4 family protein
HMMAIMLD_01030 5.3e-30 K Replication initiation factor
HMMAIMLD_01031 2.2e-22
HMMAIMLD_01032 1.8e-101 L DNA integration
HMMAIMLD_01033 7.5e-25 GM NmrA-like family
HMMAIMLD_01034 2.3e-19 GM NAD(P)H-binding
HMMAIMLD_01036 2.3e-15 L DNA integration
HMMAIMLD_01037 3.4e-31 L AAA ATPase domain
HMMAIMLD_01038 3.7e-22 3.6.4.12 L UvrD-like helicase C-terminal domain
HMMAIMLD_01039 3.1e-130 L Integrase core domain
HMMAIMLD_01040 1.5e-44
HMMAIMLD_01041 8.9e-33
HMMAIMLD_01042 2e-65
HMMAIMLD_01043 3e-16
HMMAIMLD_01044 1.5e-61 V ATPases associated with a variety of cellular activities
HMMAIMLD_01045 2.3e-198 tra L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_01046 6.3e-20 V ATPases associated with a variety of cellular activities
HMMAIMLD_01047 7.1e-73 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HMMAIMLD_01048 2.5e-76 K Transcriptional regulatory protein, C terminal
HMMAIMLD_01049 2.6e-25 K Cro/C1-type HTH DNA-binding domain
HMMAIMLD_01050 4.8e-110 K Replication initiation factor
HMMAIMLD_01051 1.8e-29
HMMAIMLD_01052 5.2e-109 L DNA integration
HMMAIMLD_01053 1.2e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMMAIMLD_01054 2e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMMAIMLD_01055 1.4e-164 dprA LU DNA protecting protein DprA
HMMAIMLD_01056 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMMAIMLD_01057 1.6e-154 D DNA integration
HMMAIMLD_01058 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
HMMAIMLD_01059 8e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMMAIMLD_01060 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMMAIMLD_01061 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMMAIMLD_01062 8.9e-95 S Protein of unknown function (DUF1440)
HMMAIMLD_01063 4.7e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
HMMAIMLD_01064 2.3e-71 yqkB S Belongs to the HesB IscA family
HMMAIMLD_01065 3.4e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HMMAIMLD_01066 5.7e-94 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HMMAIMLD_01067 1.3e-81 yebR 1.8.4.14 T GAF domain-containing protein
HMMAIMLD_01068 3.2e-245 U Belongs to the purine-cytosine permease (2.A.39) family
HMMAIMLD_01069 8e-243 codA 3.5.4.1 F cytosine deaminase
HMMAIMLD_01070 0.0 oppD EP Psort location Cytoplasmic, score
HMMAIMLD_01072 1.4e-256 rarA L recombination factor protein RarA
HMMAIMLD_01073 1.3e-117 S Protein of unknown function (DUF554)
HMMAIMLD_01074 9.3e-245 yhjX P Major Facilitator Superfamily
HMMAIMLD_01075 4.2e-17 lmrB EGP Major facilitator Superfamily
HMMAIMLD_01076 1.1e-225 L Transposase
HMMAIMLD_01077 4.9e-263 arcD E Amino acid permease
HMMAIMLD_01078 4.5e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HMMAIMLD_01079 2e-104 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HMMAIMLD_01080 1.6e-07 C Domain of unknown function (DUF4145)
HMMAIMLD_01081 1.1e-228 tnp L MULE transposase domain
HMMAIMLD_01082 3.1e-65 yncA 2.3.1.79 S Maltose acetyltransferase
HMMAIMLD_01083 1.2e-91 S Fic/DOC family
HMMAIMLD_01084 4.6e-97 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
HMMAIMLD_01085 1.6e-122 EGP Sugar (and other) transporter
HMMAIMLD_01086 3.4e-92 EGP Sugar (and other) transporter
HMMAIMLD_01087 7.3e-71 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
HMMAIMLD_01088 1.8e-105 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
HMMAIMLD_01089 2.5e-214 2.6.1.1 E Aminotransferase
HMMAIMLD_01092 7.5e-34 S Phage minor capsid protein 2
HMMAIMLD_01093 5.7e-72 S Phage minor capsid protein 2
HMMAIMLD_01094 5.1e-164 I alpha/beta hydrolase fold
HMMAIMLD_01095 1.8e-95 K Acetyltransferase (GNAT) domain
HMMAIMLD_01097 9.8e-161 S DUF218 domain
HMMAIMLD_01098 5.6e-166 1.1.1.346 C Aldo keto reductase
HMMAIMLD_01099 2.6e-80 hmpT S ECF-type riboflavin transporter, S component
HMMAIMLD_01100 4.8e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HMMAIMLD_01101 3e-237 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
HMMAIMLD_01102 4e-62 ywkB S Membrane transport protein
HMMAIMLD_01103 7.1e-203 xerS L Belongs to the 'phage' integrase family
HMMAIMLD_01104 9.4e-180 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMMAIMLD_01105 8.5e-226 4.4.1.8 E Aminotransferase, class I
HMMAIMLD_01106 3.1e-195 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
HMMAIMLD_01107 1.6e-70 C Zinc-binding dehydrogenase
HMMAIMLD_01108 1.6e-59 C Zinc-binding dehydrogenase
HMMAIMLD_01109 5.4e-102 proW P ABC transporter, permease protein
HMMAIMLD_01110 9.3e-141 proV E ABC transporter, ATP-binding protein
HMMAIMLD_01111 1.8e-108 proWZ P ABC transporter permease
HMMAIMLD_01112 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
HMMAIMLD_01113 4.7e-76 K Transcriptional regulator
HMMAIMLD_01114 4.2e-74 O OsmC-like protein
HMMAIMLD_01115 1.1e-74 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HMMAIMLD_01116 9.1e-27 C Flavodoxin
HMMAIMLD_01117 2.5e-30 GM NmrA-like family
HMMAIMLD_01118 3.3e-45 K transcriptional regulator
HMMAIMLD_01119 3.9e-107 L Integrase
HMMAIMLD_01120 6.1e-71 ydjP I Alpha/beta hydrolase family
HMMAIMLD_01121 4.3e-139 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HMMAIMLD_01122 5.3e-18 citR K sugar-binding domain protein
HMMAIMLD_01123 1.4e-61 citR K sugar-binding domain protein
HMMAIMLD_01124 1e-183 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HMMAIMLD_01126 1.4e-162 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HMMAIMLD_01127 1.5e-79 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_01128 6.2e-37 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HMMAIMLD_01129 5.5e-57 ydiI Q Thioesterase superfamily
HMMAIMLD_01130 5.3e-158 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HMMAIMLD_01131 1.2e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HMMAIMLD_01132 1.6e-216 G Transporter, major facilitator family protein
HMMAIMLD_01133 1.9e-208 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HMMAIMLD_01134 4.4e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HMMAIMLD_01135 1.3e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMMAIMLD_01136 2.5e-40 gcvR T Belongs to the UPF0237 family
HMMAIMLD_01137 1.8e-243 XK27_08635 S UPF0210 protein
HMMAIMLD_01138 2.8e-179 yobV1 K WYL domain
HMMAIMLD_01139 1.6e-67 S pyridoxamine 5-phosphate
HMMAIMLD_01140 6.3e-34
HMMAIMLD_01142 2.2e-63
HMMAIMLD_01143 7.4e-11 yicL EG EamA-like transporter family
HMMAIMLD_01144 1.8e-64 yicL EG EamA-like transporter family
HMMAIMLD_01146 7e-60 S Domain of unknown function (DUF4352)
HMMAIMLD_01147 0.0 1.3.5.4 C FAD binding domain
HMMAIMLD_01148 1e-165 K LysR substrate binding domain
HMMAIMLD_01149 7.7e-160 rssA S Phospholipase, patatin family
HMMAIMLD_01150 8.8e-215 phbA 2.3.1.9 I Belongs to the thiolase family
HMMAIMLD_01151 1.9e-179 S AI-2E family transporter
HMMAIMLD_01152 2.6e-124 S membrane transporter protein
HMMAIMLD_01153 3.2e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HMMAIMLD_01154 2.6e-194 V Beta-lactamase
HMMAIMLD_01155 9.2e-228
HMMAIMLD_01157 3.1e-153 S Alpha/beta hydrolase of unknown function (DUF915)
HMMAIMLD_01158 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMMAIMLD_01159 1.4e-164 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HMMAIMLD_01160 1.2e-163 endA F DNA RNA non-specific endonuclease
HMMAIMLD_01161 3.2e-269 pipD E Dipeptidase
HMMAIMLD_01163 1.5e-253 yifK E Amino acid permease
HMMAIMLD_01165 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMMAIMLD_01166 1.5e-236 N Uncharacterized conserved protein (DUF2075)
HMMAIMLD_01168 3.4e-79 ndk 2.7.4.6 F Belongs to the NDK family
HMMAIMLD_01169 2.2e-99 padR K Virulence activator alpha C-term
HMMAIMLD_01170 2.1e-94 padC Q Phenolic acid decarboxylase
HMMAIMLD_01172 5e-220 I transferase activity, transferring acyl groups other than amino-acyl groups
HMMAIMLD_01174 1.7e-143 ET Bacterial periplasmic substrate-binding proteins
HMMAIMLD_01175 1.8e-158 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HMMAIMLD_01176 1.7e-226 aadAT EK Aminotransferase, class I
HMMAIMLD_01178 2.1e-10
HMMAIMLD_01180 2.3e-07 S RelE-like toxin of type II toxin-antitoxin system HigB
HMMAIMLD_01181 4.7e-32 higA K Helix-turn-helix XRE-family like proteins
HMMAIMLD_01182 1.1e-30 S Sugar efflux transporter for intercellular exchange
HMMAIMLD_01184 4.4e-80 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HMMAIMLD_01185 4.2e-37 tdh 1.1.1.14 C Zinc-binding dehydrogenase
HMMAIMLD_01186 3.5e-260 guaD 3.5.4.3 F Amidohydrolase family
HMMAIMLD_01187 6.6e-215 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HMMAIMLD_01190 9.2e-58 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
HMMAIMLD_01191 1.7e-64 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMMAIMLD_01192 2.9e-81 tlpA2 L Transposase IS200 like
HMMAIMLD_01193 3.5e-238 L transposase, IS605 OrfB family
HMMAIMLD_01194 4e-38 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMMAIMLD_01195 1.6e-55 rmeB K transcriptional regulator, MerR family
HMMAIMLD_01196 2.7e-132 ybbM S Uncharacterised protein family (UPF0014)
HMMAIMLD_01197 2.2e-111 ybbL S ABC transporter, ATP-binding protein
HMMAIMLD_01198 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HMMAIMLD_01199 2.1e-21 S Protein of unknown function (DUF4256)
HMMAIMLD_01200 4.1e-31 K Transcriptional regulator
HMMAIMLD_01201 5.2e-84 L hmm pf00665
HMMAIMLD_01202 7.8e-44 L Helix-turn-helix domain
HMMAIMLD_01203 3.7e-27 K Acetyltransferase (GNAT) domain
HMMAIMLD_01204 3.2e-228 tnp L MULE transposase domain
HMMAIMLD_01205 1.2e-10
HMMAIMLD_01206 9.1e-58 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HMMAIMLD_01207 0.0 L Type III restriction enzyme, res subunit
HMMAIMLD_01209 2.6e-100 K DNA-templated transcription, initiation
HMMAIMLD_01210 1.1e-228 tnp L MULE transposase domain
HMMAIMLD_01212 4.2e-86 tnp L MULE transposase domain
HMMAIMLD_01213 4.8e-64 L Integrase core domain
HMMAIMLD_01214 3.9e-100 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HMMAIMLD_01215 6.5e-28 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMMAIMLD_01216 0.0 M domain protein
HMMAIMLD_01217 1.3e-193 tra L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_01218 3.1e-64 slyA K helix_turn_helix multiple antibiotic resistance protein
HMMAIMLD_01220 5.2e-26 L Integrase core domain
HMMAIMLD_01221 7e-43 repA S Replication initiator protein A
HMMAIMLD_01222 3.8e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMMAIMLD_01223 3.4e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMMAIMLD_01224 9.2e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMMAIMLD_01225 1.1e-103 wecD3 K Acetyltransferase (GNAT) family
HMMAIMLD_01226 4.7e-311 ubiB S ABC1 family
HMMAIMLD_01227 2.3e-130 1.14.12.17 C Oxidoreductase NAD-binding domain
HMMAIMLD_01228 1.7e-81 tlpA2 L Transposase IS200 like
HMMAIMLD_01229 3.5e-238 L transposase, IS605 OrfB family
HMMAIMLD_01230 1.7e-165 GK ROK family
HMMAIMLD_01231 1.1e-40
HMMAIMLD_01232 4.2e-80 copY K Copper transport repressor CopY TcrY
HMMAIMLD_01234 1.6e-76 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HMMAIMLD_01235 1.4e-170 mutR K Transcriptional activator, Rgg GadR MutR family
HMMAIMLD_01236 1.2e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HMMAIMLD_01237 3.2e-229 gntT EG Gluconate
HMMAIMLD_01238 7.1e-181 K Transcriptional regulator, LacI family
HMMAIMLD_01239 9.5e-61 yneR
HMMAIMLD_01240 5.7e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HMMAIMLD_01241 2.2e-96 V VanZ like family
HMMAIMLD_01242 2.1e-290 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HMMAIMLD_01243 2.4e-49 ywnB S NAD(P)H-binding
HMMAIMLD_01244 3.5e-65 yjcE P Sodium proton antiporter
HMMAIMLD_01245 5.9e-76
HMMAIMLD_01246 1.9e-183
HMMAIMLD_01247 5.4e-239 L transposase, IS605 OrfB family
HMMAIMLD_01248 2.5e-80 tlpA2 L Transposase IS200 like
HMMAIMLD_01249 4e-127 narI 1.7.5.1 C Nitrate reductase
HMMAIMLD_01250 1.2e-101 narJ C Nitrate reductase delta subunit
HMMAIMLD_01251 0.0 narH 1.7.5.1 C Respiratory nitrate reductase beta C-terminal
HMMAIMLD_01252 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMMAIMLD_01253 1.4e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HMMAIMLD_01254 1.9e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HMMAIMLD_01255 1.2e-230 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HMMAIMLD_01256 7.2e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HMMAIMLD_01257 2.4e-98 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HMMAIMLD_01258 4.2e-40
HMMAIMLD_01259 1.4e-77 nreA T GAF domain
HMMAIMLD_01260 1.4e-182 comP 2.7.13.3 F Sensor histidine kinase
HMMAIMLD_01261 4e-116 nreC K PFAM regulatory protein LuxR
HMMAIMLD_01262 1.2e-39
HMMAIMLD_01263 6.7e-184
HMMAIMLD_01264 2e-169 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
HMMAIMLD_01266 1.3e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HMMAIMLD_01267 1.3e-162 hipB K Helix-turn-helix
HMMAIMLD_01268 1.5e-58 yitW S Iron-sulfur cluster assembly protein
HMMAIMLD_01269 2.4e-215 narK P Major Facilitator Superfamily
HMMAIMLD_01270 1e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HMMAIMLD_01271 6.4e-35 moaD 2.8.1.12 H ThiS family
HMMAIMLD_01272 2.2e-72 moaE 2.8.1.12 H MoaE protein
HMMAIMLD_01273 1.7e-57 S Flavodoxin
HMMAIMLD_01274 7.3e-170 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMMAIMLD_01275 1.5e-143 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
HMMAIMLD_01276 5.9e-230 ndh 1.6.99.3 C NADH dehydrogenase
HMMAIMLD_01277 8e-54 yitW S Iron-sulfur cluster assembly protein
HMMAIMLD_01278 4.7e-19 M1-755 S Domain of unknown function (DUF1858)
HMMAIMLD_01279 1.6e-257 XK27_04775 S PAS domain
HMMAIMLD_01280 3.2e-142 EG EamA-like transporter family
HMMAIMLD_01281 2.1e-246 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMMAIMLD_01282 7.8e-178 fecB P Periplasmic binding protein
HMMAIMLD_01283 4.2e-272 sufB O assembly protein SufB
HMMAIMLD_01284 5.5e-83 nifU C SUF system FeS assembly protein, NifU family
HMMAIMLD_01285 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMMAIMLD_01286 5.8e-244 sufD O FeS assembly protein SufD
HMMAIMLD_01287 3.6e-143 sufC O FeS assembly ATPase SufC
HMMAIMLD_01288 3.9e-33 feoA P FeoA domain
HMMAIMLD_01289 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HMMAIMLD_01290 6.7e-23 S Virus attachment protein p12 family
HMMAIMLD_01291 2.7e-155 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HMMAIMLD_01292 7.2e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMMAIMLD_01293 2.5e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMMAIMLD_01294 7.1e-217 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
HMMAIMLD_01295 8.7e-90 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HMMAIMLD_01296 1.4e-198 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HMMAIMLD_01297 1.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMMAIMLD_01298 5e-104
HMMAIMLD_01299 7.4e-214 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMMAIMLD_01300 7.6e-13 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
HMMAIMLD_01301 3.8e-213 ydiN G Major Facilitator Superfamily
HMMAIMLD_01303 3.2e-37 dtpT U amino acid peptide transporter
HMMAIMLD_01304 2.7e-187 dtpT U amino acid peptide transporter
HMMAIMLD_01306 5.1e-153 S Sucrose-6F-phosphate phosphohydrolase
HMMAIMLD_01307 3.3e-158 1.6.5.2 GM NAD(P)H-binding
HMMAIMLD_01308 5.5e-158 S Alpha beta hydrolase
HMMAIMLD_01309 1.2e-237 lmrB EGP Major facilitator Superfamily
HMMAIMLD_01311 0.0 S Bacterial membrane protein YfhO
HMMAIMLD_01312 1.6e-49
HMMAIMLD_01313 0.0 kup P Transport of potassium into the cell
HMMAIMLD_01315 3.9e-284 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMMAIMLD_01316 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HMMAIMLD_01317 0.0 yjbQ P TrkA C-terminal domain protein
HMMAIMLD_01318 4.8e-276 pipD E Dipeptidase
HMMAIMLD_01319 7e-164 S Alpha/beta hydrolase of unknown function (DUF915)
HMMAIMLD_01320 1.8e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMMAIMLD_01321 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMMAIMLD_01322 1.6e-168 T Calcineurin-like phosphoesterase superfamily domain
HMMAIMLD_01323 4.3e-160 EGP Major facilitator Superfamily
HMMAIMLD_01324 6.8e-202 mdtG EGP Major facilitator Superfamily
HMMAIMLD_01325 5.3e-251 yhdP S Transporter associated domain
HMMAIMLD_01326 1.3e-11 naiP EGP Major facilitator Superfamily
HMMAIMLD_01327 4.5e-110 S Type III restriction enzyme, res subunit
HMMAIMLD_01329 1.7e-77 S N-methyltransferase activity
HMMAIMLD_01330 4.5e-196 S Domain of unknown function (DUF3440)
HMMAIMLD_01334 1.1e-94 ps461 3.5.1.104 M hydrolase, family 25
HMMAIMLD_01335 5.4e-24 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HMMAIMLD_01339 5.3e-17
HMMAIMLD_01340 7.3e-30 S GDSL-like Lipase/Acylhydrolase
HMMAIMLD_01343 3.4e-50
HMMAIMLD_01344 4.1e-142 rny D peptidase
HMMAIMLD_01345 1.2e-80 S Phage tail protein
HMMAIMLD_01346 1.1e-206 M Phage tail tape measure protein TP901
HMMAIMLD_01347 2.4e-26
HMMAIMLD_01348 5.6e-46 S Phage tail tube protein
HMMAIMLD_01349 3.3e-25
HMMAIMLD_01350 4e-19
HMMAIMLD_01351 1.1e-32 S Phage head-tail joining protein
HMMAIMLD_01352 4.8e-29 S Phage gp6-like head-tail connector protein
HMMAIMLD_01353 3.6e-120 S Phage capsid family
HMMAIMLD_01354 3.1e-80 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HMMAIMLD_01355 4.3e-146 S portal protein
HMMAIMLD_01357 1.2e-268 S Phage Terminase
HMMAIMLD_01358 1.9e-40 L Phage terminase, small subunit
HMMAIMLD_01359 1.2e-31 L HNH nucleases
HMMAIMLD_01360 9.3e-21 S Transcriptional regulator, RinA family
HMMAIMLD_01361 2e-17 mazG S MazG nucleotide pyrophosphohydrolase domain
HMMAIMLD_01371 1.3e-11
HMMAIMLD_01373 6.6e-43 rusA L Endodeoxyribonuclease RusA
HMMAIMLD_01377 4.4e-10 K Cro/C1-type HTH DNA-binding domain
HMMAIMLD_01379 2.3e-41 dnaC 3.4.21.53 L IstB-like ATP binding protein
HMMAIMLD_01380 5.4e-114 S calcium ion binding
HMMAIMLD_01381 9.1e-38 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMMAIMLD_01382 3e-117 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HMMAIMLD_01383 2.1e-153 recT L RecT family
HMMAIMLD_01386 7.7e-09 S Domain of unknown function (DUF771)
HMMAIMLD_01390 8.8e-94 K BRO family, N-terminal domain
HMMAIMLD_01391 1.1e-12 K Helix-turn-helix XRE-family like proteins
HMMAIMLD_01392 5e-52 3.4.21.88 K Peptidase S24-like
HMMAIMLD_01394 5.2e-100 L Belongs to the 'phage' integrase family
HMMAIMLD_01395 6.9e-193 naiP EGP Major facilitator Superfamily
HMMAIMLD_01396 4.6e-47 K LysR substrate binding domain protein
HMMAIMLD_01397 4e-33 K LysR substrate binding domain protein
HMMAIMLD_01398 3.4e-216 E GDSL-like Lipase/Acylhydrolase family
HMMAIMLD_01399 1.5e-194 lplA 6.3.1.20 H Lipoate-protein ligase
HMMAIMLD_01400 3.1e-259 lpdA 1.8.1.4 C Dehydrogenase
HMMAIMLD_01401 1.4e-200 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMMAIMLD_01402 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HMMAIMLD_01403 1.4e-182 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HMMAIMLD_01404 1.1e-09 yphJ 4.1.1.44 S decarboxylase
HMMAIMLD_01405 1e-30 yphJ 4.1.1.44 S decarboxylase
HMMAIMLD_01406 2.8e-54 azlD E Branched-chain amino acid transport
HMMAIMLD_01407 2.3e-122 azlC E azaleucine resistance protein AzlC
HMMAIMLD_01408 7.1e-286 thrC 4.2.3.1 E Threonine synthase
HMMAIMLD_01409 2.7e-233 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HMMAIMLD_01410 5.2e-156 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMMAIMLD_01411 3.5e-99 K Acetyltransferase (GNAT) domain
HMMAIMLD_01412 5.3e-113 ylbE GM NAD(P)H-binding
HMMAIMLD_01413 7.3e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMMAIMLD_01414 6.9e-133 S Belongs to the UPF0246 family
HMMAIMLD_01415 4.6e-98
HMMAIMLD_01416 3.2e-161 degV S EDD domain protein, DegV family
HMMAIMLD_01417 0.0 FbpA K Fibronectin-binding protein
HMMAIMLD_01418 7.1e-239 L transposase, IS605 OrfB family
HMMAIMLD_01419 8.3e-13 tlpA2 L Transposase IS200 like
HMMAIMLD_01420 1.6e-120 L Transposase
HMMAIMLD_01422 4.4e-23 XK27_01125 L PFAM IS66 Orf2 family protein
HMMAIMLD_01423 9.1e-289 L Transposase IS66 family
HMMAIMLD_01424 1.5e-89 L Transposase
HMMAIMLD_01425 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HMMAIMLD_01426 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HMMAIMLD_01427 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
HMMAIMLD_01428 9e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMMAIMLD_01429 3e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMMAIMLD_01430 6.4e-70 esbA S Family of unknown function (DUF5322)
HMMAIMLD_01431 3.1e-71 rnhA 3.1.26.4 L Ribonuclease HI
HMMAIMLD_01432 8.7e-110 XK27_02070 S Nitroreductase family
HMMAIMLD_01433 8.9e-156 yckB ET Belongs to the bacterial solute-binding protein 3 family
HMMAIMLD_01434 1e-117 yecS E ABC transporter permease
HMMAIMLD_01435 2.1e-45 L Transposase
HMMAIMLD_01436 1.1e-228 tnp L MULE transposase domain
HMMAIMLD_01437 5.1e-37 L Integrase core domain
HMMAIMLD_01438 6.9e-118 L Integrase core domain
HMMAIMLD_01440 4.6e-185 L PFAM Integrase catalytic region
HMMAIMLD_01441 7.7e-44 V HNH endonuclease
HMMAIMLD_01442 1.1e-228 tnp L MULE transposase domain
HMMAIMLD_01443 3.2e-254 nylA 3.5.1.4 J Belongs to the amidase family
HMMAIMLD_01444 4e-204 arcD S C4-dicarboxylate anaerobic carrier
HMMAIMLD_01445 6.9e-192 ytjP 3.5.1.18 E Dipeptidase
HMMAIMLD_01446 2.5e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HMMAIMLD_01447 8.9e-83 F Hydrolase, NUDIX family
HMMAIMLD_01448 3.4e-211 S Type IV secretion-system coupling protein DNA-binding domain
HMMAIMLD_01449 0.0 tetP J elongation factor G
HMMAIMLD_01450 4.8e-190 L Helix-turn-helix domain
HMMAIMLD_01451 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMMAIMLD_01452 4.6e-111 ypsA S Belongs to the UPF0398 family
HMMAIMLD_01453 1e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMMAIMLD_01454 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HMMAIMLD_01455 3.7e-160 EG EamA-like transporter family
HMMAIMLD_01456 1.5e-191 C Aldo keto reductase family protein
HMMAIMLD_01457 1.3e-121 ypuA S Protein of unknown function (DUF1002)
HMMAIMLD_01458 4.7e-134 dnaD L DnaD domain protein
HMMAIMLD_01459 2.1e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HMMAIMLD_01460 1.6e-88 ypmB S Protein conserved in bacteria
HMMAIMLD_01461 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMMAIMLD_01462 6.4e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HMMAIMLD_01463 2.4e-181 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HMMAIMLD_01464 2.8e-210 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HMMAIMLD_01465 1.5e-205 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMMAIMLD_01466 9.5e-96 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_01467 2.3e-103 pstA P Phosphate transport system permease protein PstA
HMMAIMLD_01468 2.4e-98 pstC P probably responsible for the translocation of the substrate across the membrane
HMMAIMLD_01469 9e-92 pstS P Phosphate
HMMAIMLD_01470 1.8e-272 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HMMAIMLD_01471 1.2e-154 yitU 3.1.3.104 S hydrolase
HMMAIMLD_01472 4.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMMAIMLD_01473 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HMMAIMLD_01474 8.7e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMMAIMLD_01475 1.4e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMMAIMLD_01476 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMMAIMLD_01477 4.6e-57 ycsI S Protein of unknown function (DUF1445)
HMMAIMLD_01478 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HMMAIMLD_01479 2.1e-45 L Transposase
HMMAIMLD_01480 4.9e-170 L Integrase core domain
HMMAIMLD_01481 2.8e-160 tra L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_01482 1.5e-111 L Helix-turn-helix domain
HMMAIMLD_01483 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMMAIMLD_01484 3.7e-260 yfnA E Amino Acid
HMMAIMLD_01485 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HMMAIMLD_01486 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMMAIMLD_01487 5.4e-40 ylqC S Belongs to the UPF0109 family
HMMAIMLD_01488 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HMMAIMLD_01489 1.1e-122 phoU P Plays a role in the regulation of phosphate uptake
HMMAIMLD_01490 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMMAIMLD_01491 9.4e-153 pstA P Phosphate transport system permease protein PstA
HMMAIMLD_01492 3.3e-153 pstC P probably responsible for the translocation of the substrate across the membrane
HMMAIMLD_01493 5.1e-159 pstS P Phosphate
HMMAIMLD_01494 8.6e-125 K Transcriptional regulatory protein, C-terminal domain protein
HMMAIMLD_01495 4e-20 L Transposase
HMMAIMLD_01496 1.1e-228 tnp L MULE transposase domain
HMMAIMLD_01498 4.4e-23 XK27_01125 L PFAM IS66 Orf2 family protein
HMMAIMLD_01499 1.1e-289 L Transposase IS66 family
HMMAIMLD_01500 2.2e-98
HMMAIMLD_01501 1.6e-171 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_01502 7.6e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMMAIMLD_01503 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMMAIMLD_01504 2e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMMAIMLD_01505 0.0 smc D Required for chromosome condensation and partitioning
HMMAIMLD_01506 5.2e-130 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMMAIMLD_01507 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMMAIMLD_01508 2.8e-164 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMMAIMLD_01509 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMMAIMLD_01510 1.7e-304 yloV S DAK2 domain fusion protein YloV
HMMAIMLD_01511 3.6e-58 asp S Asp23 family, cell envelope-related function
HMMAIMLD_01512 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HMMAIMLD_01513 1.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HMMAIMLD_01514 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HMMAIMLD_01515 5.3e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMMAIMLD_01516 0.0 KLT serine threonine protein kinase
HMMAIMLD_01517 2.2e-131 stp 3.1.3.16 T phosphatase
HMMAIMLD_01518 2e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMMAIMLD_01519 2.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMMAIMLD_01520 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMMAIMLD_01521 2.3e-221 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMMAIMLD_01522 3.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMMAIMLD_01523 3.9e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HMMAIMLD_01524 2.5e-15
HMMAIMLD_01525 1.3e-307 recN L May be involved in recombinational repair of damaged DNA
HMMAIMLD_01526 6.2e-76 argR K Regulates arginine biosynthesis genes
HMMAIMLD_01527 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HMMAIMLD_01528 6.2e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMMAIMLD_01529 1e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMMAIMLD_01530 1.9e-256 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMMAIMLD_01531 2.6e-160 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMMAIMLD_01532 6.8e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMMAIMLD_01533 4.1e-72 yqhY S Asp23 family, cell envelope-related function
HMMAIMLD_01534 8.1e-207 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMMAIMLD_01535 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HMMAIMLD_01536 9e-53 ysxB J Cysteine protease Prp
HMMAIMLD_01537 1.8e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HMMAIMLD_01538 2.8e-114 K Transcriptional regulator
HMMAIMLD_01540 1.2e-132
HMMAIMLD_01541 2.6e-208 3.5.1.104 M hydrolase, family 25
HMMAIMLD_01542 8.4e-30 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HMMAIMLD_01543 1.5e-10
HMMAIMLD_01549 1.5e-78 spoIVFA GT2,GT4 D peptidase
HMMAIMLD_01550 1.8e-305 ydhO 3.4.14.13 M Prophage endopeptidase tail
HMMAIMLD_01551 6.6e-164 S Phage tail protein
HMMAIMLD_01552 0.0 M Phage tail tape measure protein TP901
HMMAIMLD_01553 1.7e-51 S Phage tail assembly chaperone proteins, TAC
HMMAIMLD_01554 8.7e-113 S Phage tail tube protein
HMMAIMLD_01555 2.2e-18 S Protein of unknown function (DUF806)
HMMAIMLD_01556 2.4e-32 S Bacteriophage HK97-gp10, putative tail-component
HMMAIMLD_01557 5.5e-14 S Phage head-tail joining protein
HMMAIMLD_01558 6.2e-48
HMMAIMLD_01559 3.9e-176 G Phage capsid family
HMMAIMLD_01560 6.7e-187 S Phage portal protein
HMMAIMLD_01562 0.0 S Phage Terminase
HMMAIMLD_01563 6.6e-77 L Phage terminase, small subunit
HMMAIMLD_01564 8.6e-42
HMMAIMLD_01565 3.8e-132
HMMAIMLD_01566 1.5e-20
HMMAIMLD_01569 1.4e-26 L Psort location Cytoplasmic, score
HMMAIMLD_01570 6.9e-95 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMMAIMLD_01571 2.2e-154 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HMMAIMLD_01572 3.7e-145 recT L RecT family
HMMAIMLD_01576 1.9e-10
HMMAIMLD_01580 1.1e-96 K BRO family, N-terminal domain
HMMAIMLD_01581 4.7e-07 cro K Helix-turn-helix XRE-family like proteins
HMMAIMLD_01582 1e-14 3.4.21.88 K Helix-turn-helix
HMMAIMLD_01583 3.9e-17 E Zn peptidase
HMMAIMLD_01587 5.7e-200 S Phage integrase family
HMMAIMLD_01588 1.5e-92 dut S Protein conserved in bacteria
HMMAIMLD_01589 5.1e-176
HMMAIMLD_01590 7e-148
HMMAIMLD_01591 4.7e-13
HMMAIMLD_01592 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
HMMAIMLD_01593 8.5e-173 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMMAIMLD_01594 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
HMMAIMLD_01595 1.5e-71 yqhL P Rhodanese-like protein
HMMAIMLD_01596 1.2e-180 glk 2.7.1.2 G Glucokinase
HMMAIMLD_01597 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HMMAIMLD_01598 1.1e-116 gluP 3.4.21.105 S Peptidase, S54 family
HMMAIMLD_01599 2.4e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMMAIMLD_01600 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMMAIMLD_01601 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HMMAIMLD_01602 0.0 S membrane
HMMAIMLD_01603 1.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMMAIMLD_01604 5.2e-116 udk 2.7.1.48 F Cytidine monophosphokinase
HMMAIMLD_01605 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMMAIMLD_01606 4.3e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMMAIMLD_01607 7.8e-60 yodB K Transcriptional regulator, HxlR family
HMMAIMLD_01608 7.6e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMMAIMLD_01609 1.2e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMMAIMLD_01610 4.1e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HMMAIMLD_01611 7.2e-132 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMMAIMLD_01612 1.4e-186 L PFAM Integrase catalytic region
HMMAIMLD_01613 3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMMAIMLD_01614 1.6e-233 V MatE
HMMAIMLD_01615 9e-281 arlS 2.7.13.3 T Histidine kinase
HMMAIMLD_01616 5.6e-121 K response regulator
HMMAIMLD_01617 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HMMAIMLD_01618 2.3e-96 yceD S Uncharacterized ACR, COG1399
HMMAIMLD_01619 1.7e-215 ylbM S Belongs to the UPF0348 family
HMMAIMLD_01620 1.4e-141 yqeM Q Methyltransferase
HMMAIMLD_01621 1.8e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMMAIMLD_01622 7.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HMMAIMLD_01623 9.2e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMMAIMLD_01624 2.6e-49 yhbY J RNA-binding protein
HMMAIMLD_01625 2.6e-216 yqeH S Ribosome biogenesis GTPase YqeH
HMMAIMLD_01626 2.2e-96 yqeG S HAD phosphatase, family IIIA
HMMAIMLD_01627 2e-25 yoaK S Protein of unknown function (DUF1275)
HMMAIMLD_01628 8.1e-18 yoaK S Protein of unknown function (DUF1275)
HMMAIMLD_01629 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMMAIMLD_01630 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HMMAIMLD_01631 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMMAIMLD_01632 2.5e-172 dnaI L Primosomal protein DnaI
HMMAIMLD_01633 3.6e-252 dnaB L replication initiation and membrane attachment
HMMAIMLD_01634 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMMAIMLD_01635 1.1e-104 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMMAIMLD_01636 2.1e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMMAIMLD_01637 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMMAIMLD_01638 2.9e-139 aroD S Serine hydrolase (FSH1)
HMMAIMLD_01639 1.8e-114 ybhL S Belongs to the BI1 family
HMMAIMLD_01640 3.2e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HMMAIMLD_01641 7.8e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMMAIMLD_01642 6.5e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMMAIMLD_01643 3.3e-58 ytzB S Small secreted protein
HMMAIMLD_01644 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMMAIMLD_01645 7.7e-211 ecsB U ABC transporter
HMMAIMLD_01646 2.3e-133 ecsA V ABC transporter, ATP-binding protein
HMMAIMLD_01647 1.4e-77 hit FG histidine triad
HMMAIMLD_01649 3.1e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMMAIMLD_01650 5.7e-180 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMMAIMLD_01651 9.8e-56 yheA S Belongs to the UPF0342 family
HMMAIMLD_01652 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMMAIMLD_01653 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HMMAIMLD_01655 1.7e-36
HMMAIMLD_01657 5.7e-203 folP 2.5.1.15 H dihydropteroate synthase
HMMAIMLD_01658 2.6e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HMMAIMLD_01659 9.8e-244 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMMAIMLD_01660 1.5e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HMMAIMLD_01661 8.4e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HMMAIMLD_01662 7.1e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMMAIMLD_01663 9e-119 S CAAX protease self-immunity
HMMAIMLD_01664 1.6e-180 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HMMAIMLD_01665 1e-110
HMMAIMLD_01666 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
HMMAIMLD_01667 2.8e-162 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMMAIMLD_01668 3.2e-256 S Putative peptidoglycan binding domain
HMMAIMLD_01669 5.1e-87 uspA T Belongs to the universal stress protein A family
HMMAIMLD_01670 2.9e-273 pepV 3.5.1.18 E dipeptidase PepV
HMMAIMLD_01671 2.2e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMMAIMLD_01672 1.5e-62 3.2.1.23 S Domain of unknown function DUF302
HMMAIMLD_01673 1e-298 ytgP S Polysaccharide biosynthesis protein
HMMAIMLD_01674 1.3e-41
HMMAIMLD_01675 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMMAIMLD_01676 9.2e-127 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
HMMAIMLD_01677 4.4e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMMAIMLD_01678 8.2e-140 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMMAIMLD_01679 3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMMAIMLD_01680 1.3e-51
HMMAIMLD_01681 8.6e-17 tag 3.2.2.20 L glycosylase
HMMAIMLD_01682 2.6e-253 EGP Major facilitator Superfamily
HMMAIMLD_01683 1.6e-84 perR P Belongs to the Fur family
HMMAIMLD_01684 3.5e-247 cycA E Amino acid permease
HMMAIMLD_01685 1.2e-21
HMMAIMLD_01688 2.2e-240 L transposase, IS605 OrfB family
HMMAIMLD_01689 2.9e-81 tlpA2 L Transposase IS200 like
HMMAIMLD_01690 4.5e-115 K Transcriptional regulator, TetR family
HMMAIMLD_01691 1.1e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HMMAIMLD_01692 1.6e-85 ykhA 3.1.2.20 I Thioesterase superfamily
HMMAIMLD_01693 1.1e-62 lytE M LysM domain protein
HMMAIMLD_01694 3.9e-198 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HMMAIMLD_01695 4.6e-236 F Permease
HMMAIMLD_01696 4.9e-162 sufD O Uncharacterized protein family (UPF0051)
HMMAIMLD_01697 1.1e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMMAIMLD_01698 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HMMAIMLD_01699 2e-110 XK27_05795 P ABC transporter permease
HMMAIMLD_01700 6.9e-142 ET Bacterial periplasmic substrate-binding proteins
HMMAIMLD_01701 1e-11 qacC P COG2076 Membrane transporters of cations and cationic drugs
HMMAIMLD_01713 9.8e-77
HMMAIMLD_01716 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
HMMAIMLD_01717 2.5e-181 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMMAIMLD_01718 2.9e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
HMMAIMLD_01719 1.3e-229 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HMMAIMLD_01720 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMMAIMLD_01721 4.7e-39 ptsH G phosphocarrier protein HPR
HMMAIMLD_01723 0.0 clpE O Belongs to the ClpA ClpB family
HMMAIMLD_01724 6.4e-128 3.6.1.13, 3.6.1.55 F NUDIX domain
HMMAIMLD_01725 4.9e-110 pncA Q Isochorismatase family
HMMAIMLD_01726 5e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMMAIMLD_01727 8.3e-51 L Helix-turn-helix domain
HMMAIMLD_01728 6.2e-85 L hmm pf00665
HMMAIMLD_01729 1.7e-97 S Pfam:DUF3816
HMMAIMLD_01730 2.3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HMMAIMLD_01731 5.5e-136 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMMAIMLD_01732 6.5e-162 EG EamA-like transporter family
HMMAIMLD_01733 3.5e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
HMMAIMLD_01734 1.1e-289 L Transposase IS66 family
HMMAIMLD_01735 4.4e-23 XK27_01125 L PFAM IS66 Orf2 family protein
HMMAIMLD_01737 1.2e-14
HMMAIMLD_01738 4.7e-157 V ABC transporter, ATP-binding protein
HMMAIMLD_01739 2.3e-63 gntR1 K Transcriptional regulator, GntR family
HMMAIMLD_01740 5e-173 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMMAIMLD_01741 1.4e-88 S Bacterial membrane protein, YfhO
HMMAIMLD_01742 5.9e-212 S Psort location CytoplasmicMembrane, score
HMMAIMLD_01743 3.6e-148 ykoT GT2 M Glycosyl transferase family 2
HMMAIMLD_01744 3.1e-103 glfT1 1.1.1.133 S Glycosyltransferase like family 2
HMMAIMLD_01745 1.3e-95 M transferase activity, transferring glycosyl groups
HMMAIMLD_01746 2.2e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMMAIMLD_01747 1.8e-165 ykoT GT2 M Glycosyl transferase family 2
HMMAIMLD_01748 2.3e-140 yueF S AI-2E family transporter
HMMAIMLD_01749 4.9e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HMMAIMLD_01750 8.1e-09
HMMAIMLD_01751 1.2e-59 M repeat protein
HMMAIMLD_01752 1.9e-56 acmD 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMMAIMLD_01753 1.4e-217 L Transposase
HMMAIMLD_01754 4.6e-202 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HMMAIMLD_01755 6.6e-220 glf 5.4.99.9 M UDP-galactopyranose mutase
HMMAIMLD_01756 1.1e-225 L Transposase
HMMAIMLD_01757 1.4e-52 cps3I G Acyltransferase family
HMMAIMLD_01758 4.5e-45 M biosynthesis protein
HMMAIMLD_01759 1.2e-94 cps3F
HMMAIMLD_01760 1.5e-146 cps1D M Domain of unknown function (DUF4422)
HMMAIMLD_01761 1.1e-118 rfbP M Bacterial sugar transferase
HMMAIMLD_01762 3.2e-147 recX 2.4.1.337 GT4 S Regulatory protein RecX
HMMAIMLD_01763 1.3e-07
HMMAIMLD_01764 3.8e-31 S Protein of unknown function (DUF2922)
HMMAIMLD_01765 2.3e-138 yihY S Belongs to the UPF0761 family
HMMAIMLD_01766 0.0 XK27_08315 M Sulfatase
HMMAIMLD_01767 5e-167 map 3.4.11.18 E Methionine Aminopeptidase
HMMAIMLD_01768 8.5e-78 fld C Flavodoxin
HMMAIMLD_01769 3e-75 gtcA S Teichoic acid glycosylation protein
HMMAIMLD_01772 1.5e-231 yfmL 3.6.4.13 L DEAD DEAH box helicase
HMMAIMLD_01773 6.4e-190 mocA S Oxidoreductase
HMMAIMLD_01774 4.9e-63 S Domain of unknown function (DUF4828)
HMMAIMLD_01775 1.4e-104 yvdD 3.2.2.10 S Belongs to the LOG family
HMMAIMLD_01776 1.9e-161 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HMMAIMLD_01777 3.1e-289 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HMMAIMLD_01778 3.6e-140 S NADPH-dependent FMN reductase
HMMAIMLD_01779 7.8e-34 yneR S Belongs to the HesB IscA family
HMMAIMLD_01780 2.2e-301 ybiT S ABC transporter, ATP-binding protein
HMMAIMLD_01781 1.7e-84 dps P Belongs to the Dps family
HMMAIMLD_01782 4.6e-105
HMMAIMLD_01783 1.3e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMMAIMLD_01784 1.2e-100 K helix_turn_helix multiple antibiotic resistance protein
HMMAIMLD_01785 6.2e-62 fsr EGP Major Facilitator Superfamily
HMMAIMLD_01786 2.1e-23 fsr EGP Major Facilitator Superfamily
HMMAIMLD_01787 6.8e-10 fsr EGP Major Facilitator Superfamily
HMMAIMLD_01788 2.1e-99 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HMMAIMLD_01789 7.8e-103 S CAAX protease self-immunity
HMMAIMLD_01791 6.3e-120 Q Methyltransferase domain
HMMAIMLD_01792 8.6e-91 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HMMAIMLD_01793 2.8e-51 K 2 iron, 2 sulfur cluster binding
HMMAIMLD_01794 0.0 mco Q Multicopper oxidase
HMMAIMLD_01795 1.4e-89 S Aminoacyl-tRNA editing domain
HMMAIMLD_01796 5.9e-74 ddaH 3.5.3.18 E Amidinotransferase
HMMAIMLD_01798 4.6e-194 nhaC C Na H antiporter NhaC
HMMAIMLD_01799 3.9e-180 S Phosphotransferase system, EIIC
HMMAIMLD_01800 5.1e-22 D mRNA cleavage
HMMAIMLD_01801 7.2e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HMMAIMLD_01802 6.2e-59 L Helix-turn-helix domain
HMMAIMLD_01803 1.6e-154 L hmm pf00665
HMMAIMLD_01804 5.2e-134 L PFAM transposase, IS4 family protein
HMMAIMLD_01805 2.5e-128 L PFAM transposase, IS4 family protein
HMMAIMLD_01806 1.2e-263 npr 1.11.1.1 C NADH oxidase
HMMAIMLD_01807 1.1e-225 L Transposase
HMMAIMLD_01808 1.1e-228 tnp L MULE transposase domain
HMMAIMLD_01809 2.9e-19 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMMAIMLD_01810 4.5e-32 L Transposase
HMMAIMLD_01811 1.3e-170 L Integrase core domain
HMMAIMLD_01812 6.4e-90 L Transposase
HMMAIMLD_01813 8.3e-51 L Helix-turn-helix domain
HMMAIMLD_01814 6.2e-85 L hmm pf00665
HMMAIMLD_01815 1.2e-112 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HMMAIMLD_01816 5.4e-46 D Di-iron-containing protein involved in the repair of iron-sulfur clusters
HMMAIMLD_01817 5.6e-33 copZ P Heavy-metal-associated domain
HMMAIMLD_01818 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HMMAIMLD_01819 3.7e-81
HMMAIMLD_01820 5.2e-170 L Transposase and inactivated derivatives IS30 family
HMMAIMLD_01821 2.3e-53 tra L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_01822 3.2e-144 tra L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_01823 1.1e-49 K TRANSCRIPTIONal
HMMAIMLD_01824 4.1e-264 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMMAIMLD_01825 6.7e-187 yegS 2.7.1.107 G Lipid kinase
HMMAIMLD_01826 1.5e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMMAIMLD_01827 6.3e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMMAIMLD_01828 1.5e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMMAIMLD_01829 1.4e-161 camS S sex pheromone
HMMAIMLD_01830 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMMAIMLD_01831 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HMMAIMLD_01832 1.4e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HMMAIMLD_01833 3.6e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMMAIMLD_01834 5.8e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HMMAIMLD_01835 4.4e-138 IQ reductase
HMMAIMLD_01836 1.5e-214 L transposase, IS605 OrfB family
HMMAIMLD_01837 1e-180 S interspecies interaction between organisms
HMMAIMLD_01838 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HMMAIMLD_01839 2.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMMAIMLD_01840 8.3e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMMAIMLD_01841 1.4e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMMAIMLD_01842 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMMAIMLD_01843 3e-148 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMMAIMLD_01844 2.8e-61 rplQ J Ribosomal protein L17
HMMAIMLD_01845 5.8e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMMAIMLD_01846 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMMAIMLD_01847 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMMAIMLD_01848 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HMMAIMLD_01849 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMMAIMLD_01850 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMMAIMLD_01851 5.8e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMMAIMLD_01852 2.1e-65 rplO J Binds to the 23S rRNA
HMMAIMLD_01853 6.5e-24 rpmD J Ribosomal protein L30
HMMAIMLD_01854 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMMAIMLD_01855 3.9e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMMAIMLD_01856 3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMMAIMLD_01857 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMMAIMLD_01858 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMMAIMLD_01859 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMMAIMLD_01860 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMMAIMLD_01861 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMMAIMLD_01862 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMMAIMLD_01863 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
HMMAIMLD_01864 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMMAIMLD_01865 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMMAIMLD_01866 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMMAIMLD_01867 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMMAIMLD_01868 3.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMMAIMLD_01869 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMMAIMLD_01870 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
HMMAIMLD_01871 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMMAIMLD_01872 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HMMAIMLD_01873 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMMAIMLD_01874 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMMAIMLD_01875 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMMAIMLD_01876 1.6e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
HMMAIMLD_01877 2.2e-213 ykiI
HMMAIMLD_01878 5.6e-135 puuD S peptidase C26
HMMAIMLD_01879 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMMAIMLD_01880 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMMAIMLD_01881 1.1e-104 K Bacterial regulatory proteins, tetR family
HMMAIMLD_01882 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMMAIMLD_01883 4.8e-79 ctsR K Belongs to the CtsR family
HMMAIMLD_01884 9.7e-194 adhP 1.1.1.1 C alcohol dehydrogenase
HMMAIMLD_01885 1.3e-131 XK27_07210 6.1.1.6 S B3 4 domain
HMMAIMLD_01886 2.7e-120 J 2'-5' RNA ligase superfamily
HMMAIMLD_01888 1.8e-53 S ABC-type cobalt transport system, permease component
HMMAIMLD_01889 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMMAIMLD_01890 1.3e-45 IQ reductase
HMMAIMLD_01891 1e-10 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMMAIMLD_01897 7.9e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HMMAIMLD_01898 3.9e-268 lysP E amino acid
HMMAIMLD_01900 9.2e-155 I alpha/beta hydrolase fold
HMMAIMLD_01901 9.1e-116 lssY 3.6.1.27 I phosphatase
HMMAIMLD_01902 3.7e-82 S Threonine/Serine exporter, ThrE
HMMAIMLD_01903 2.4e-125 thrE S Putative threonine/serine exporter
HMMAIMLD_01904 2.8e-28 cspA K Cold shock protein
HMMAIMLD_01905 4.5e-123 sirR K iron dependent repressor
HMMAIMLD_01906 1.7e-162 czcD P cation diffusion facilitator family transporter
HMMAIMLD_01907 2.5e-116 S membrane
HMMAIMLD_01908 4.5e-110 S VIT family
HMMAIMLD_01909 1.3e-84 usp1 T Belongs to the universal stress protein A family
HMMAIMLD_01910 8.1e-33 elaA S GNAT family
HMMAIMLD_01911 5.7e-217 S CAAX protease self-immunity
HMMAIMLD_01912 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMMAIMLD_01913 2e-58
HMMAIMLD_01914 1.9e-74 merR K MerR HTH family regulatory protein
HMMAIMLD_01915 1.1e-267 lmrB EGP Major facilitator Superfamily
HMMAIMLD_01916 8.9e-114 S Domain of unknown function (DUF4811)
HMMAIMLD_01917 7.2e-149 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HMMAIMLD_01918 2e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HMMAIMLD_01920 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMMAIMLD_01921 7.9e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HMMAIMLD_01922 2.4e-189 I Alpha beta
HMMAIMLD_01923 2.1e-120 ung2 3.2.2.27 L Uracil-DNA glycosylase
HMMAIMLD_01924 2.1e-252 yjjP S Putative threonine/serine exporter
HMMAIMLD_01925 6.6e-162 mleR K LysR family transcriptional regulator
HMMAIMLD_01926 2.6e-123 yflS P Sodium:sulfate symporter transmembrane region
HMMAIMLD_01927 8.1e-62 yflS P Sodium:sulfate symporter transmembrane region
HMMAIMLD_01928 3.6e-215 frdC 1.3.5.4 C FAD binding domain
HMMAIMLD_01929 1.6e-223 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMMAIMLD_01930 1.9e-91 XK27_09620 S NADPH-dependent FMN reductase
HMMAIMLD_01931 1e-182 XK27_09615 S reductase
HMMAIMLD_01932 1.2e-230 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HMMAIMLD_01933 5.3e-79 mleR K LysR family
HMMAIMLD_01934 3.9e-61 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HMMAIMLD_01935 2.5e-228 tnp L MULE transposase domain
HMMAIMLD_01936 1.5e-124 S EcsC protein family
HMMAIMLD_01937 1.9e-26 tnp L DDE domain
HMMAIMLD_01938 2.2e-49 yqeB S Pyrimidine dimer DNA glycosylase
HMMAIMLD_01939 5.7e-177 L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_01940 3.1e-75 tnp L MULE transposase domain
HMMAIMLD_01941 2.8e-108 tnp L MULE transposase domain
HMMAIMLD_01942 6.2e-59 L Helix-turn-helix domain
HMMAIMLD_01943 1.5e-155 L hmm pf00665
HMMAIMLD_01944 3.6e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMMAIMLD_01945 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
HMMAIMLD_01946 1.8e-195 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HMMAIMLD_01947 2e-296 scrB 3.2.1.26 GH32 G invertase
HMMAIMLD_01948 1.2e-260 S Uncharacterized protein conserved in bacteria (DUF2252)
HMMAIMLD_01949 3.2e-164 K LysR substrate binding domain
HMMAIMLD_01950 1.5e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HMMAIMLD_01951 3.9e-110
HMMAIMLD_01953 6.2e-266 yjeM E Amino Acid
HMMAIMLD_01954 3.7e-168 ponA V Beta-lactamase enzyme family
HMMAIMLD_01955 3.4e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMMAIMLD_01956 5.9e-97
HMMAIMLD_01957 5.9e-199 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HMMAIMLD_01958 4.7e-108 lssY 3.6.1.27 I Acid phosphatase homologues
HMMAIMLD_01959 1.3e-53 S MazG-like family
HMMAIMLD_01960 0.0 L Helicase C-terminal domain protein
HMMAIMLD_01961 2.7e-70 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HMMAIMLD_01962 3.2e-95 K transcriptional regulator
HMMAIMLD_01963 7.5e-133 lmrB EGP Major facilitator Superfamily
HMMAIMLD_01964 7.1e-239 L transposase, IS605 OrfB family
HMMAIMLD_01965 4.9e-81 tlpA2 L Transposase IS200 like
HMMAIMLD_01966 5.9e-50 lmrB EGP Major facilitator Superfamily
HMMAIMLD_01967 3.7e-14 S Domain of unknown function (DUF4811)
HMMAIMLD_01968 6.2e-246 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMMAIMLD_01971 3.5e-38 S Cytochrome B5
HMMAIMLD_01972 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMMAIMLD_01973 2.7e-213 2.1.1.14 E methionine synthase, vitamin-B12 independent
HMMAIMLD_01974 2e-10 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
HMMAIMLD_01975 1e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
HMMAIMLD_01976 1.6e-88 3.2.1.17 NU mannosyl-glycoprotein
HMMAIMLD_01977 1e-66 wecD K Acetyltransferase (GNAT) family
HMMAIMLD_01978 3.2e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HMMAIMLD_01979 5.9e-82 S Psort location Cytoplasmic, score
HMMAIMLD_01980 2.3e-72 K helix_turn_helix, mercury resistance
HMMAIMLD_01981 1.6e-134 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
HMMAIMLD_01982 2.5e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HMMAIMLD_01983 4.8e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMMAIMLD_01984 8.4e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HMMAIMLD_01985 6.3e-134 ycsF S LamB/YcsF family
HMMAIMLD_01986 1.5e-209 ycsG P Natural resistance-associated macrophage protein
HMMAIMLD_01987 1.6e-208 EGP Major facilitator Superfamily
HMMAIMLD_01988 5.2e-256 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HMMAIMLD_01989 1.1e-52 trxA O Belongs to the thioredoxin family
HMMAIMLD_01990 2.6e-69 mleP3 S Membrane transport protein
HMMAIMLD_01991 1.1e-73 mleP3 S Membrane transport protein
HMMAIMLD_01993 1.4e-225 L transposase, IS605 OrfB family
HMMAIMLD_01994 4.4e-45 L Transposase IS200 like
HMMAIMLD_01995 1.5e-242 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMMAIMLD_01996 8e-242 yfnA E amino acid
HMMAIMLD_01997 3.5e-58 S NADPH-dependent FMN reductase
HMMAIMLD_01999 2.6e-157 L Thioesterase-like superfamily
HMMAIMLD_02000 1.8e-50 lacA S transferase hexapeptide repeat
HMMAIMLD_02001 7.3e-261 argH 4.3.2.1 E argininosuccinate lyase
HMMAIMLD_02002 1.3e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMMAIMLD_02003 1.4e-242 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMMAIMLD_02004 2.7e-64 L Transposase IS200 like
HMMAIMLD_02005 1.7e-173 L transposase, IS605 OrfB family
HMMAIMLD_02006 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMMAIMLD_02007 2.2e-102 K Transcriptional regulator
HMMAIMLD_02008 9.3e-24 XK27_06785 V ABC transporter
HMMAIMLD_02009 1e-168 M Membrane
HMMAIMLD_02010 3.8e-52 S FMN_bind
HMMAIMLD_02011 0.0 yhcA V ABC transporter, ATP-binding protein
HMMAIMLD_02012 6.1e-123 bm3R1 K Bacterial regulatory proteins, tetR family
HMMAIMLD_02013 2.3e-51 rocF 3.5.3.1, 3.5.3.11 E Arginase family
HMMAIMLD_02014 3.9e-173 1.3.1.9 S Nitronate monooxygenase
HMMAIMLD_02015 4.7e-54 K Helix-turn-helix domain
HMMAIMLD_02016 1.8e-104 S Domain of unknown function (DUF4767)
HMMAIMLD_02017 1.5e-116
HMMAIMLD_02019 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HMMAIMLD_02020 0.0 norZ 1.7.2.5 P Cytochrome C and Quinol oxidase polypeptide I
HMMAIMLD_02021 5.7e-270 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HMMAIMLD_02022 1e-113 2.7.6.5 T Region found in RelA / SpoT proteins
HMMAIMLD_02023 3.1e-79 K response regulator
HMMAIMLD_02024 6.4e-131 sptS 2.7.13.3 T Histidine kinase
HMMAIMLD_02025 5.3e-175 coaA 2.7.1.33 F Pantothenic acid kinase
HMMAIMLD_02026 2.1e-102 2.3.1.128 K acetyltransferase
HMMAIMLD_02027 4.8e-134 IQ Dehydrogenase reductase
HMMAIMLD_02028 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMMAIMLD_02029 2.5e-161 EG EamA-like transporter family
HMMAIMLD_02030 0.0 helD 3.6.4.12 L DNA helicase
HMMAIMLD_02031 8.6e-119 dedA S SNARE associated Golgi protein
HMMAIMLD_02032 4e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HMMAIMLD_02033 2.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMMAIMLD_02034 1e-209 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HMMAIMLD_02035 1.2e-134 pnuC H nicotinamide mononucleotide transporter
HMMAIMLD_02036 3.6e-296 ybeC E amino acid
HMMAIMLD_02037 1.7e-52 tlpA2 L Transposase IS200 like
HMMAIMLD_02038 1.7e-105 L transposase, IS605 OrfB family
HMMAIMLD_02039 8.7e-107 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMMAIMLD_02040 2.1e-141 mnaA 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
HMMAIMLD_02042 1.4e-202 V domain protein
HMMAIMLD_02043 3.3e-92 K Transcriptional regulator (TetR family)
HMMAIMLD_02044 1.1e-187 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HMMAIMLD_02045 4.4e-169
HMMAIMLD_02047 4e-83 zur P Belongs to the Fur family
HMMAIMLD_02048 1.7e-105 gmk2 2.7.4.8 F Guanylate kinase
HMMAIMLD_02049 1.3e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HMMAIMLD_02050 1.2e-205 yfnA E Amino Acid
HMMAIMLD_02051 7.1e-239 L transposase, IS605 OrfB family
HMMAIMLD_02052 2.9e-81 tlpA2 L Transposase IS200 like
HMMAIMLD_02053 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMMAIMLD_02054 1.2e-177 3.4.11.5 E Releases the N-terminal proline from various substrates
HMMAIMLD_02055 8.7e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HMMAIMLD_02056 9.1e-277 S Uncharacterized protein conserved in bacteria (DUF2325)
HMMAIMLD_02057 1.2e-182 1.17.4.1 F Ribonucleotide reductase, small chain
HMMAIMLD_02058 9.7e-169 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
HMMAIMLD_02059 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMMAIMLD_02060 1.4e-83 nrdI F NrdI Flavodoxin like
HMMAIMLD_02061 5.1e-110 M ErfK YbiS YcfS YnhG
HMMAIMLD_02062 1.8e-206 nrnB S DHHA1 domain
HMMAIMLD_02063 2.9e-290 S ABC transporter, ATP-binding protein
HMMAIMLD_02064 5.9e-180 ABC-SBP S ABC transporter
HMMAIMLD_02065 1e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HMMAIMLD_02066 1e-131 XK27_08845 S ABC transporter, ATP-binding protein
HMMAIMLD_02068 5.7e-225 amtB P ammonium transporter
HMMAIMLD_02069 3.3e-234 mepA V MATE efflux family protein
HMMAIMLD_02070 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HMMAIMLD_02071 4.3e-258 pgi 5.3.1.9 G Belongs to the GPI family
HMMAIMLD_02072 3e-184 fruR3 K Transcriptional regulator, LacI family
HMMAIMLD_02073 1.1e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HMMAIMLD_02074 2.6e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMMAIMLD_02075 3e-56 trxA1 O Belongs to the thioredoxin family
HMMAIMLD_02076 2.6e-141 terC P membrane
HMMAIMLD_02077 1.5e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMMAIMLD_02078 9.7e-169 corA P CorA-like Mg2+ transporter protein
HMMAIMLD_02079 6e-228 pbuX F xanthine permease
HMMAIMLD_02080 5.5e-150 qorB 1.6.5.2 GM NmrA-like family
HMMAIMLD_02081 2.5e-126 pgm3 G phosphoglycerate mutase family
HMMAIMLD_02082 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMMAIMLD_02083 2e-85
HMMAIMLD_02084 1.7e-106 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HMMAIMLD_02085 1.2e-100 dps P Belongs to the Dps family
HMMAIMLD_02086 8.7e-34 copZ P Heavy-metal-associated domain
HMMAIMLD_02087 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HMMAIMLD_02088 4.4e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HMMAIMLD_02089 2e-180 iunH2 3.2.2.1 F nucleoside hydrolase
HMMAIMLD_02090 1.6e-100 S ABC-type cobalt transport system, permease component
HMMAIMLD_02091 3.7e-257 cbiO1 S ABC transporter, ATP-binding protein
HMMAIMLD_02092 2.2e-114 P Cobalt transport protein
HMMAIMLD_02093 1.2e-16 yvlA
HMMAIMLD_02094 0.0 yjcE P Sodium proton antiporter
HMMAIMLD_02095 2.6e-191 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HMMAIMLD_02096 1.6e-73 O OsmC-like protein
HMMAIMLD_02097 4.1e-186 D Alpha beta
HMMAIMLD_02098 8.4e-75 K Transcriptional regulator
HMMAIMLD_02099 4.5e-160
HMMAIMLD_02100 8.7e-20
HMMAIMLD_02101 2.1e-59
HMMAIMLD_02102 3.1e-75 uspA T universal stress protein
HMMAIMLD_02104 1.6e-129 qmcA O prohibitin homologues
HMMAIMLD_02105 5.5e-245 glpT G Major Facilitator Superfamily
HMMAIMLD_02106 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMMAIMLD_02107 2.3e-136 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
HMMAIMLD_02108 8.3e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMMAIMLD_02109 9.8e-259 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMMAIMLD_02110 1.7e-193 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HMMAIMLD_02111 2.8e-40 ulaB 2.7.1.194 G Phosphotransferase system galactitol-specific IIB component
HMMAIMLD_02112 6.1e-44 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMMAIMLD_02113 6.2e-131 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMMAIMLD_02114 3.2e-225 L Transposase
HMMAIMLD_02115 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMMAIMLD_02116 7e-245 fucP G Major Facilitator Superfamily
HMMAIMLD_02117 2.1e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HMMAIMLD_02118 2.9e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMMAIMLD_02119 3.9e-168 deoR K sugar-binding domain protein
HMMAIMLD_02120 1.1e-113 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMMAIMLD_02121 5.3e-200 S Domain of unknown function (DUF4432)
HMMAIMLD_02122 3.2e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMMAIMLD_02123 3.7e-260 G PTS system Galactitol-specific IIC component
HMMAIMLD_02124 6e-188 K helix_turn _helix lactose operon repressor
HMMAIMLD_02125 1.3e-282 yjeM E Amino Acid
HMMAIMLD_02127 4.2e-228 tnp L MULE transposase domain
HMMAIMLD_02128 2.3e-19 tra L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_02129 4.4e-49 tnp L MULE transposase domain
HMMAIMLD_02130 3.1e-150 L Helix-turn-helix domain
HMMAIMLD_02131 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HMMAIMLD_02132 1.3e-15
HMMAIMLD_02133 1.4e-101 K Bacterial regulatory proteins, tetR family
HMMAIMLD_02134 7.5e-18 L transposase and inactivated derivatives, IS30 family
HMMAIMLD_02135 1.5e-123 L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_02136 9.6e-95 tnpR1 L Resolvase, N terminal domain
HMMAIMLD_02137 1.1e-228 tnp L MULE transposase domain
HMMAIMLD_02138 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HMMAIMLD_02139 9.7e-149 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HMMAIMLD_02140 6.4e-131 gntR K UbiC transcription regulator-associated domain protein
HMMAIMLD_02141 7.1e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMMAIMLD_02142 3.2e-130
HMMAIMLD_02143 1.3e-265 pipD E Dipeptidase
HMMAIMLD_02144 9.8e-157 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HMMAIMLD_02145 3.4e-86 M1-874 K Domain of unknown function (DUF1836)
HMMAIMLD_02146 4.3e-89 GM epimerase
HMMAIMLD_02147 3.6e-252 yhdP S Transporter associated domain
HMMAIMLD_02148 2.4e-83 nrdI F Belongs to the NrdI family
HMMAIMLD_02149 6.5e-75 S 3-demethylubiquinone-9 3-methyltransferase
HMMAIMLD_02150 1.4e-207 yeaN P Transporter, major facilitator family protein
HMMAIMLD_02151 4.4e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMMAIMLD_02152 9.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMMAIMLD_02153 1.4e-81 uspA T universal stress protein
HMMAIMLD_02154 1.1e-77 K AsnC family
HMMAIMLD_02155 1.9e-141 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMMAIMLD_02156 2.5e-178 K helix_turn _helix lactose operon repressor
HMMAIMLD_02157 0.0 pepF E oligoendopeptidase F
HMMAIMLD_02158 5.4e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMMAIMLD_02159 5.3e-124 S Membrane
HMMAIMLD_02160 4.6e-39 L Transposase
HMMAIMLD_02161 2.4e-144 L 4.5 Transposon and IS
HMMAIMLD_02162 0.0 dld 1.1.5.12 C D-lactate dehydrogenase, membrane binding
HMMAIMLD_02163 4.5e-288 L Transposase IS66 family
HMMAIMLD_02164 4.4e-23 XK27_01125 L PFAM IS66 Orf2 family protein
HMMAIMLD_02166 4.8e-22 L hmm pf00665
HMMAIMLD_02167 2.4e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HMMAIMLD_02169 3.2e-225 L Transposase
HMMAIMLD_02170 1.2e-184 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
HMMAIMLD_02171 1e-190 L Transposase and inactivated derivatives, IS30 family
HMMAIMLD_02172 4.8e-97 2.1.1.14 E methionine synthase, vitamin-B12 independent
HMMAIMLD_02173 5.2e-64 2.1.1.14 E methionine synthase, vitamin-B12 independent
HMMAIMLD_02174 1.1e-228 tnp L MULE transposase domain
HMMAIMLD_02175 4.5e-85 2.5.1.105 P Cation efflux family
HMMAIMLD_02176 3.4e-51 L Resolvase, N terminal domain
HMMAIMLD_02178 0.0 copB 3.6.3.4 P P-type ATPase
HMMAIMLD_02179 6.5e-75 K Copper transport repressor CopY TcrY
HMMAIMLD_02180 1.5e-225 L Transposase
HMMAIMLD_02181 1.8e-37 Q ubiE/COQ5 methyltransferase family
HMMAIMLD_02182 3.4e-171 L Integrase core domain
HMMAIMLD_02183 1.9e-46 L Transposase
HMMAIMLD_02184 1.7e-33 crtB 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
HMMAIMLD_02185 9.1e-30 L Helix-turn-helix domain
HMMAIMLD_02186 1.3e-156 L hmm pf00665
HMMAIMLD_02187 8.6e-276 lacS G Transporter
HMMAIMLD_02188 0.0 rafA 3.2.1.22 G alpha-galactosidase
HMMAIMLD_02189 4.1e-181 galR K Transcriptional regulator
HMMAIMLD_02190 1.5e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HMMAIMLD_02191 1.8e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMMAIMLD_02192 1.2e-182 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HMMAIMLD_02193 1.6e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
HMMAIMLD_02194 2.7e-96 yxkA S Phosphatidylethanolamine-binding protein
HMMAIMLD_02195 6.9e-36
HMMAIMLD_02196 6.6e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMMAIMLD_02197 7.4e-121 tcyB U Binding-protein-dependent transport system inner membrane component
HMMAIMLD_02198 5.7e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HMMAIMLD_02199 2e-52
HMMAIMLD_02200 9e-170 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMMAIMLD_02201 1.7e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMMAIMLD_02202 6.9e-147 pnuC H nicotinamide mononucleotide transporter
HMMAIMLD_02203 1.2e-91 ymdB S Macro domain protein
HMMAIMLD_02204 0.0 pepO 3.4.24.71 O Peptidase family M13
HMMAIMLD_02205 2.4e-229 pbuG S permease
HMMAIMLD_02206 2.5e-46
HMMAIMLD_02207 6.9e-215 S Putative metallopeptidase domain
HMMAIMLD_02208 4.7e-205 3.1.3.1 S associated with various cellular activities
HMMAIMLD_02209 1.3e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HMMAIMLD_02210 5.2e-65 yeaO S Protein of unknown function, DUF488
HMMAIMLD_02212 4.8e-125 yrkL S Flavodoxin-like fold
HMMAIMLD_02213 5.6e-55
HMMAIMLD_02214 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HMMAIMLD_02215 1e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMMAIMLD_02216 4.1e-102
HMMAIMLD_02217 9.5e-26
HMMAIMLD_02218 5.9e-169 scrR K Transcriptional regulator, LacI family
HMMAIMLD_02219 2.9e-173 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMMAIMLD_02220 2.6e-46 czrA K Transcriptional regulator, ArsR family
HMMAIMLD_02221 1.8e-75 argR K Regulates arginine biosynthesis genes
HMMAIMLD_02222 5.5e-124 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HMMAIMLD_02223 5e-158 hrtB V ABC transporter permease
HMMAIMLD_02224 6.9e-107 ygfC K Bacterial regulatory proteins, tetR family
HMMAIMLD_02225 7.1e-189 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HMMAIMLD_02226 1.7e-277 mntH P H( )-stimulated, divalent metal cation uptake system
HMMAIMLD_02227 2.1e-20
HMMAIMLD_02228 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMMAIMLD_02229 6.2e-71 L nuclease
HMMAIMLD_02230 2.9e-162 F DNA/RNA non-specific endonuclease
HMMAIMLD_02231 2.5e-228 tnp L MULE transposase domain
HMMAIMLD_02232 2.3e-153 L transposase, IS605 OrfB family
HMMAIMLD_02233 2.8e-55 tlpA2 L Transposase IS200 like
HMMAIMLD_02234 2.8e-15 tlpA2 L Transposase IS200 like
HMMAIMLD_02235 6.6e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMMAIMLD_02236 1.1e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMMAIMLD_02237 8e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMMAIMLD_02238 0.0 asnB 6.3.5.4 E Asparagine synthase
HMMAIMLD_02239 8.7e-220 lysP E amino acid
HMMAIMLD_02241 4.4e-23 XK27_01125 L PFAM IS66 Orf2 family protein
HMMAIMLD_02242 1.1e-289 L Transposase IS66 family
HMMAIMLD_02243 1.2e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMMAIMLD_02244 2.9e-81 tlpA2 L Transposase IS200 like
HMMAIMLD_02245 1.6e-238 L transposase, IS605 OrfB family
HMMAIMLD_02246 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMMAIMLD_02247 1.1e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMMAIMLD_02248 4.8e-154 jag S R3H domain protein
HMMAIMLD_02249 3.4e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMMAIMLD_02250 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMMAIMLD_02251 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)