ORF_ID e_value Gene_name EC_number CAZy COGs Description
KOBEAFEE_00001 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KOBEAFEE_00002 1.1e-158 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KOBEAFEE_00003 9e-20 yaaA S S4 domain protein YaaA
KOBEAFEE_00004 8.4e-154 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KOBEAFEE_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOBEAFEE_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOBEAFEE_00007 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
KOBEAFEE_00008 8.7e-64 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KOBEAFEE_00009 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KOBEAFEE_00010 5.6e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
KOBEAFEE_00011 4.3e-58 tlpA2 L Transposase IS200 like
KOBEAFEE_00012 1.1e-159 L transposase, IS605 OrfB family
KOBEAFEE_00013 9.5e-117 S Glycosyl transferase family 2
KOBEAFEE_00014 6.7e-65 D peptidase
KOBEAFEE_00015 0.0 asnB 6.3.5.4 E Asparagine synthase
KOBEAFEE_00016 4.6e-28 yiiE S Protein of unknown function (DUF1211)
KOBEAFEE_00017 1.1e-18 yiiE S Protein of unknown function (DUF1211)
KOBEAFEE_00018 6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KOBEAFEE_00019 1.4e-246 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KOBEAFEE_00020 9.8e-18 yneR
KOBEAFEE_00021 1.8e-231 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KOBEAFEE_00022 2.5e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
KOBEAFEE_00023 1.5e-97 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KOBEAFEE_00024 1.6e-97 tnp2 L Transposase
KOBEAFEE_00025 4.9e-152 mdtG EGP Major facilitator Superfamily
KOBEAFEE_00026 1.7e-14 yobS K transcriptional regulator
KOBEAFEE_00027 1.1e-108 glcU U sugar transport
KOBEAFEE_00028 2e-170 yjjP S Putative threonine/serine exporter
KOBEAFEE_00029 1.1e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
KOBEAFEE_00031 3.7e-96 yicL EG EamA-like transporter family
KOBEAFEE_00032 8.8e-159 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
KOBEAFEE_00033 3.5e-111 dcm 2.1.1.37 L C-5 cytosine-specific DNA methylase
KOBEAFEE_00034 6e-89 V HNH endonuclease
KOBEAFEE_00035 1.6e-223 pepF E Oligopeptidase F
KOBEAFEE_00036 1.2e-48 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KOBEAFEE_00037 2.5e-23 S dextransucrase activity
KOBEAFEE_00038 1.2e-138 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
KOBEAFEE_00039 2.9e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KOBEAFEE_00041 5.2e-174 S Putative peptidoglycan binding domain
KOBEAFEE_00042 7.1e-32 K Transcriptional regulator, MarR family
KOBEAFEE_00043 5.4e-213 XK27_09600 V ABC transporter, ATP-binding protein
KOBEAFEE_00044 4.1e-229 V ABC transporter transmembrane region
KOBEAFEE_00045 7.4e-169 uhpT EGP Mycoplasma MFS transporter
KOBEAFEE_00046 2.7e-157 lctO C FMN-dependent dehydrogenase
KOBEAFEE_00047 6.1e-106 yxeH S hydrolase
KOBEAFEE_00048 4.5e-113 K response regulator
KOBEAFEE_00049 1.1e-272 vicK 2.7.13.3 T Histidine kinase
KOBEAFEE_00050 2.3e-102 yycH S YycH protein
KOBEAFEE_00051 1.1e-80 yycI S YycH protein
KOBEAFEE_00052 8.1e-54 ebh 2.1.1.80, 3.1.1.61 D YSIRK type signal peptide
KOBEAFEE_00053 2.2e-116 vicX 3.1.26.11 S domain protein
KOBEAFEE_00054 9.7e-146 htrA 3.4.21.107 O serine protease
KOBEAFEE_00055 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KOBEAFEE_00056 7.2e-208 G glycerol-3-phosphate transporter
KOBEAFEE_00057 7.5e-139 S interspecies interaction between organisms
KOBEAFEE_00058 1.1e-63 secY2 U SecY translocase
KOBEAFEE_00059 3.7e-91 asp1 S Accessory Sec system protein Asp1
KOBEAFEE_00060 6.1e-107 asp2 3.4.11.5 S Accessory Sec system protein Asp2
KOBEAFEE_00061 1.5e-31 asp3 S Accessory Sec system protein Asp3
KOBEAFEE_00062 3.2e-248 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KOBEAFEE_00066 8.4e-154 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KOBEAFEE_00067 4.4e-41 cpsJ S Glycosyltransferase like family 2
KOBEAFEE_00068 1.5e-20 M Glycosyltransferase like family 2
KOBEAFEE_00069 1.2e-111 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KOBEAFEE_00070 4.4e-87 arbx M family 8
KOBEAFEE_00071 1.3e-34 cpsJ S Glycosyltransferase like family 2
KOBEAFEE_00072 1.6e-38 S glycosyl transferase family 2
KOBEAFEE_00073 1.2e-76 M Glycosyltransferase GT-D fold
KOBEAFEE_00074 5.9e-35 cpsJ S Glycosyltransferase like family 2
KOBEAFEE_00075 1.2e-38 M family 8
KOBEAFEE_00076 2e-30 M glycosyl transferase family 8
KOBEAFEE_00077 3.6e-27 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KOBEAFEE_00078 4.5e-70 2.4.1.52 GT4 M Glycosyl transferases group 1
KOBEAFEE_00079 1.7e-150 mepA V MATE efflux family protein
KOBEAFEE_00080 1.6e-97 tnp2 L Transposase
KOBEAFEE_00081 5.6e-150 lsa S ABC transporter
KOBEAFEE_00082 6.8e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KOBEAFEE_00083 2.3e-109 puuD S peptidase C26
KOBEAFEE_00084 2.2e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KOBEAFEE_00085 1.1e-25
KOBEAFEE_00086 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
KOBEAFEE_00087 1.1e-59 uspA T Universal stress protein family
KOBEAFEE_00089 4.7e-210 glnP P ABC transporter
KOBEAFEE_00090 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KOBEAFEE_00091 3.9e-147 scrR K helix_turn _helix lactose operon repressor
KOBEAFEE_00092 1.6e-216 scrB 3.2.1.26 GH32 G invertase
KOBEAFEE_00093 4e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
KOBEAFEE_00094 2e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
KOBEAFEE_00095 7.1e-115 ntpJ P Potassium uptake protein
KOBEAFEE_00096 2.8e-58 ktrA P TrkA-N domain
KOBEAFEE_00097 2.8e-53 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KOBEAFEE_00098 4e-38 M Glycosyltransferase group 2 family protein
KOBEAFEE_00099 1.4e-19
KOBEAFEE_00100 2e-93 S Predicted membrane protein (DUF2207)
KOBEAFEE_00101 1.6e-54 bioY S BioY family
KOBEAFEE_00102 1.8e-182 lmrB EGP Major facilitator Superfamily
KOBEAFEE_00103 1.4e-93 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KOBEAFEE_00104 1.9e-72 glcR K DeoR C terminal sensor domain
KOBEAFEE_00105 2.9e-60 yceE S haloacid dehalogenase-like hydrolase
KOBEAFEE_00106 1.1e-34 S Domain of unknown function (DUF4811)
KOBEAFEE_00107 1.4e-196 lmrB EGP Major facilitator Superfamily
KOBEAFEE_00108 4.2e-32 merR K MerR HTH family regulatory protein
KOBEAFEE_00109 2.5e-38 yaeR E glyoxalase bleomycin resistance protein dioxygenase
KOBEAFEE_00110 6.9e-120 G Bacterial extracellular solute-binding protein
KOBEAFEE_00111 2.3e-79 baeR K Bacterial regulatory proteins, luxR family
KOBEAFEE_00112 2.3e-99 baeS T Histidine kinase
KOBEAFEE_00113 5.3e-80 rbsB G sugar-binding domain protein
KOBEAFEE_00114 1.4e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
KOBEAFEE_00115 6.4e-116 manY G PTS system sorbose-specific iic component
KOBEAFEE_00116 2.3e-146 manN G system, mannose fructose sorbose family IID component
KOBEAFEE_00117 1.4e-52 manO S Domain of unknown function (DUF956)
KOBEAFEE_00118 5.1e-69 mltD CBM50 M NlpC P60 family protein
KOBEAFEE_00119 4e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KOBEAFEE_00120 9.9e-166 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOBEAFEE_00121 3.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
KOBEAFEE_00122 7.9e-48 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KOBEAFEE_00123 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KOBEAFEE_00124 3.9e-106 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KOBEAFEE_00125 9.6e-39 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KOBEAFEE_00126 5.8e-46 S CRISPR-associated protein (Cas_Csn2)
KOBEAFEE_00127 8.1e-38 K transcriptional regulator PadR family
KOBEAFEE_00128 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
KOBEAFEE_00129 3.1e-16 S Putative adhesin
KOBEAFEE_00130 1.3e-16 pspC KT PspC domain
KOBEAFEE_00132 3.9e-13 S Enterocin A Immunity
KOBEAFEE_00133 8.9e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KOBEAFEE_00134 5.7e-261 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
KOBEAFEE_00135 4.3e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KOBEAFEE_00136 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KOBEAFEE_00137 1.5e-120 potB P ABC transporter permease
KOBEAFEE_00138 1.3e-103 potC U Binding-protein-dependent transport system inner membrane component
KOBEAFEE_00139 1.7e-159 potD P ABC transporter
KOBEAFEE_00140 3.5e-132 ABC-SBP S ABC transporter
KOBEAFEE_00141 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KOBEAFEE_00142 3.9e-107 XK27_08845 S ABC transporter, ATP-binding protein
KOBEAFEE_00143 1.1e-67 M ErfK YbiS YcfS YnhG
KOBEAFEE_00144 1.6e-53 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KOBEAFEE_00145 5.5e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KOBEAFEE_00146 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KOBEAFEE_00147 5.7e-102 pgm3 G phosphoglycerate mutase
KOBEAFEE_00148 6.1e-56 S CAAX protease self-immunity
KOBEAFEE_00149 3.7e-47 C Flavodoxin
KOBEAFEE_00150 1.5e-57 yphH S Cupin domain
KOBEAFEE_00151 1e-45 yphJ 4.1.1.44 S decarboxylase
KOBEAFEE_00152 2.7e-144 E methionine synthase, vitamin-B12 independent
KOBEAFEE_00153 6.7e-108 metQ1 P Belongs to the nlpA lipoprotein family
KOBEAFEE_00154 3.4e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KOBEAFEE_00155 1.3e-69 metI P ABC transporter permease
KOBEAFEE_00156 6.7e-135 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KOBEAFEE_00157 4.9e-54 drgA C nitroreductase
KOBEAFEE_00158 8.9e-178 L Probable transposase
KOBEAFEE_00159 2e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
KOBEAFEE_00160 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
KOBEAFEE_00161 6.9e-171 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KOBEAFEE_00162 7.9e-267 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
KOBEAFEE_00164 2.1e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KOBEAFEE_00165 2.4e-31 metI U ABC transporter permease
KOBEAFEE_00166 6.7e-129 metQ M Belongs to the nlpA lipoprotein family
KOBEAFEE_00167 3.2e-58 S Protein of unknown function (DUF4256)
KOBEAFEE_00170 1e-177 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KOBEAFEE_00171 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
KOBEAFEE_00172 6.9e-181 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KOBEAFEE_00173 3e-230 lpdA 1.8.1.4 C Dehydrogenase
KOBEAFEE_00174 1.6e-148 lplA 6.3.1.20 H Lipoate-protein ligase
KOBEAFEE_00175 1.4e-56 S Protein of unknown function (DUF975)
KOBEAFEE_00176 8.2e-77 E GDSL-like Lipase/Acylhydrolase family
KOBEAFEE_00177 1.6e-97 tnp2 L Transposase
KOBEAFEE_00178 1.8e-38
KOBEAFEE_00179 4.1e-27 gcvR T Belongs to the UPF0237 family
KOBEAFEE_00180 1.4e-219 XK27_08635 S UPF0210 protein
KOBEAFEE_00181 9e-88 fruR K DeoR C terminal sensor domain
KOBEAFEE_00182 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KOBEAFEE_00183 6.2e-282 fruA 2.7.1.202 GT Phosphotransferase System
KOBEAFEE_00184 3.5e-49 cps3F
KOBEAFEE_00185 2.7e-83 S Membrane
KOBEAFEE_00186 2.4e-254 E Amino acid permease
KOBEAFEE_00187 2.6e-226 cadA P P-type ATPase
KOBEAFEE_00188 6.4e-114 degV S EDD domain protein, DegV family
KOBEAFEE_00189 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KOBEAFEE_00190 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
KOBEAFEE_00191 4.7e-26 ydiI Q Thioesterase superfamily
KOBEAFEE_00192 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KOBEAFEE_00193 1.1e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KOBEAFEE_00194 4.7e-81 S L,D-transpeptidase catalytic domain
KOBEAFEE_00195 1.5e-165 EGP Major facilitator Superfamily
KOBEAFEE_00196 1.4e-21 K helix_turn_helix multiple antibiotic resistance protein
KOBEAFEE_00197 4.6e-226 pipD E Dipeptidase
KOBEAFEE_00198 3.2e-118 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KOBEAFEE_00199 2.6e-32 ywjH S Protein of unknown function (DUF1634)
KOBEAFEE_00200 1.7e-119 yxaA S membrane transporter protein
KOBEAFEE_00201 5.8e-83 lysR5 K LysR substrate binding domain
KOBEAFEE_00202 7.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
KOBEAFEE_00203 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KOBEAFEE_00204 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KOBEAFEE_00205 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
KOBEAFEE_00206 1.9e-243 lysP E amino acid
KOBEAFEE_00207 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KOBEAFEE_00219 3.7e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KOBEAFEE_00220 1.9e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KOBEAFEE_00221 4.8e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KOBEAFEE_00222 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KOBEAFEE_00223 1.1e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KOBEAFEE_00225 1.6e-55 ctsR K Belongs to the CtsR family
KOBEAFEE_00226 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KOBEAFEE_00227 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOBEAFEE_00228 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOBEAFEE_00229 5.1e-24 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
KOBEAFEE_00230 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KOBEAFEE_00231 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KOBEAFEE_00232 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KOBEAFEE_00233 3.4e-92 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KOBEAFEE_00234 1.5e-89 patB 4.4.1.8 E Aminotransferase, class I
KOBEAFEE_00235 2.5e-113 K response regulator
KOBEAFEE_00236 1.3e-141 hpk31 2.7.13.3 T Histidine kinase
KOBEAFEE_00237 9.4e-89 lacX 5.1.3.3 G Aldose 1-epimerase
KOBEAFEE_00238 3e-146 G Transporter, major facilitator family protein
KOBEAFEE_00239 2e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KOBEAFEE_00240 9.5e-246 yhcA V ABC transporter, ATP-binding protein
KOBEAFEE_00241 4.5e-35 K Bacterial regulatory proteins, tetR family
KOBEAFEE_00242 2e-223 lmrA V ABC transporter, ATP-binding protein
KOBEAFEE_00243 1.9e-253 yfiC V ABC transporter
KOBEAFEE_00245 3.2e-45 yjcF K protein acetylation
KOBEAFEE_00246 3.5e-53 L phosphatase homologous to the C-terminal domain of histone macroH2A1
KOBEAFEE_00247 1.1e-71 lemA S LemA family
KOBEAFEE_00248 1.3e-114 htpX O Belongs to the peptidase M48B family
KOBEAFEE_00250 3e-272 helD 3.6.4.12 L DNA helicase
KOBEAFEE_00251 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KOBEAFEE_00252 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KOBEAFEE_00253 5.5e-103 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KOBEAFEE_00254 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
KOBEAFEE_00255 3.2e-105 ybhR V ABC transporter
KOBEAFEE_00256 2.3e-31 K Transcriptional regulator
KOBEAFEE_00257 3.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
KOBEAFEE_00258 1.5e-151 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KOBEAFEE_00259 5.1e-128
KOBEAFEE_00260 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KOBEAFEE_00261 7e-104 tatD L hydrolase, TatD family
KOBEAFEE_00262 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KOBEAFEE_00263 1.1e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KOBEAFEE_00264 9.2e-23 veg S Biofilm formation stimulator VEG
KOBEAFEE_00265 4.7e-90 S Alpha/beta hydrolase of unknown function (DUF915)
KOBEAFEE_00266 8e-141 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
KOBEAFEE_00267 6.6e-46 argR K Regulates arginine biosynthesis genes
KOBEAFEE_00268 1.8e-116 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KOBEAFEE_00269 3.9e-155 amtB P ammonium transporter
KOBEAFEE_00270 2.9e-201 argH 4.3.2.1 E argininosuccinate lyase
KOBEAFEE_00271 2.2e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KOBEAFEE_00272 1.5e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KOBEAFEE_00273 5.8e-127 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOBEAFEE_00274 4.4e-101 pfoS S Phosphotransferase system, EIIC
KOBEAFEE_00276 1.1e-184 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KOBEAFEE_00278 5.2e-137 purR 2.4.2.7 F pur operon repressor
KOBEAFEE_00279 9.5e-47 EGP Transmembrane secretion effector
KOBEAFEE_00280 2.3e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KOBEAFEE_00281 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KOBEAFEE_00282 1.5e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KOBEAFEE_00284 5.8e-112 dkg S reductase
KOBEAFEE_00285 1.7e-24
KOBEAFEE_00286 6.2e-76 2.4.2.3 F Phosphorylase superfamily
KOBEAFEE_00287 7.4e-289 ybiT S ABC transporter, ATP-binding protein
KOBEAFEE_00288 1.3e-11 ytkL S Beta-lactamase superfamily domain
KOBEAFEE_00289 3.7e-176 L Probable transposase
KOBEAFEE_00290 1.1e-41 bCE_4747 S Beta-lactamase superfamily domain
KOBEAFEE_00291 7.2e-98 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KOBEAFEE_00292 1.6e-125 S overlaps another CDS with the same product name
KOBEAFEE_00293 1.7e-86 S overlaps another CDS with the same product name
KOBEAFEE_00295 2.7e-57 spoVK O ATPase family associated with various cellular activities (AAA)
KOBEAFEE_00296 1e-22
KOBEAFEE_00297 3.9e-37 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
KOBEAFEE_00299 3.2e-62
KOBEAFEE_00300 1.7e-104 ydcZ S Putative inner membrane exporter, YdcZ
KOBEAFEE_00301 1.5e-88 S hydrolase
KOBEAFEE_00302 1e-203 ywfO S HD domain protein
KOBEAFEE_00303 3.4e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
KOBEAFEE_00304 1.8e-32 ywiB S Domain of unknown function (DUF1934)
KOBEAFEE_00305 2.9e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KOBEAFEE_00306 4.7e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KOBEAFEE_00308 1.3e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KOBEAFEE_00309 4.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KOBEAFEE_00310 1.4e-40 rpmE2 J Ribosomal protein L31
KOBEAFEE_00311 2.2e-61
KOBEAFEE_00312 1.5e-250 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
KOBEAFEE_00315 1.8e-75 S Cell surface protein
KOBEAFEE_00317 6e-61 L Resolvase, N-terminal domain
KOBEAFEE_00318 1.5e-101 L Probable transposase
KOBEAFEE_00319 1.6e-180 pbuG S permease
KOBEAFEE_00320 5.8e-66 S Uncharacterized protein conserved in bacteria (DUF2263)
KOBEAFEE_00321 4.1e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KOBEAFEE_00322 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KOBEAFEE_00323 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KOBEAFEE_00324 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KOBEAFEE_00325 5.4e-13
KOBEAFEE_00326 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
KOBEAFEE_00327 2.5e-91 yunF F Protein of unknown function DUF72
KOBEAFEE_00328 6.6e-156 nrnB S DHHA1 domain
KOBEAFEE_00329 1.3e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KOBEAFEE_00330 2.9e-59
KOBEAFEE_00331 2e-49 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
KOBEAFEE_00332 9.2e-23 S Cytochrome B5
KOBEAFEE_00333 1.1e-19 sigH K DNA-templated transcription, initiation
KOBEAFEE_00334 5.9e-69 recX 2.4.1.337 GT4 S Regulatory protein RecX
KOBEAFEE_00335 8.5e-193 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KOBEAFEE_00336 2.6e-97 ygaC J Belongs to the UPF0374 family
KOBEAFEE_00337 6.9e-92 yueF S AI-2E family transporter
KOBEAFEE_00338 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KOBEAFEE_00339 1.8e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KOBEAFEE_00340 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KOBEAFEE_00341 0.0 lacL 3.2.1.23 G -beta-galactosidase
KOBEAFEE_00342 6.8e-289 lacS G Transporter
KOBEAFEE_00343 7.7e-111 galR K Transcriptional regulator
KOBEAFEE_00344 2e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KOBEAFEE_00345 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KOBEAFEE_00346 7.7e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KOBEAFEE_00347 0.0 rafA 3.2.1.22 G alpha-galactosidase
KOBEAFEE_00348 1.6e-97 tnp2 L Transposase
KOBEAFEE_00349 1.7e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
KOBEAFEE_00350 1.9e-22 XK27_09445 S Domain of unknown function (DUF1827)
KOBEAFEE_00351 0.0 clpE O Belongs to the ClpA ClpB family
KOBEAFEE_00352 2.6e-15
KOBEAFEE_00353 9.7e-37 ptsH G phosphocarrier protein HPR
KOBEAFEE_00354 2.6e-284 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KOBEAFEE_00355 1.1e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KOBEAFEE_00356 1.3e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
KOBEAFEE_00357 1.9e-125 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KOBEAFEE_00358 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
KOBEAFEE_00359 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KOBEAFEE_00368 5.1e-08
KOBEAFEE_00374 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
KOBEAFEE_00375 2.3e-46 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KOBEAFEE_00376 1.5e-68 coiA 3.6.4.12 S Competence protein
KOBEAFEE_00377 3.6e-231 pepF E oligoendopeptidase F
KOBEAFEE_00378 1.3e-41 yjbH Q Thioredoxin
KOBEAFEE_00379 1.9e-97 pstS P Phosphate
KOBEAFEE_00380 1.2e-118 pstC P probably responsible for the translocation of the substrate across the membrane
KOBEAFEE_00381 3.9e-122 pstA P Phosphate transport system permease protein PstA
KOBEAFEE_00382 1e-113 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KOBEAFEE_00383 6e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KOBEAFEE_00384 2.7e-56 P Plays a role in the regulation of phosphate uptake
KOBEAFEE_00385 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KOBEAFEE_00386 1.1e-79 S VIT family
KOBEAFEE_00387 2.7e-83 S membrane
KOBEAFEE_00388 7.3e-41 M1-874 K Domain of unknown function (DUF1836)
KOBEAFEE_00389 2.3e-65 hly S protein, hemolysin III
KOBEAFEE_00390 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
KOBEAFEE_00391 4.5e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOBEAFEE_00394 1.1e-13
KOBEAFEE_00395 7.8e-173 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KOBEAFEE_00396 1.3e-158 ccpA K catabolite control protein A
KOBEAFEE_00397 3.7e-42 S VanZ like family
KOBEAFEE_00398 1.5e-119 yebC K Transcriptional regulatory protein
KOBEAFEE_00399 1.3e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KOBEAFEE_00400 1.1e-120 comGA NU Type II IV secretion system protein
KOBEAFEE_00401 4.4e-98 comGB NU type II secretion system
KOBEAFEE_00402 1.8e-26 comGC U competence protein ComGC
KOBEAFEE_00403 1.1e-13
KOBEAFEE_00405 9.4e-11 S Putative Competence protein ComGF
KOBEAFEE_00407 5.8e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
KOBEAFEE_00408 9.3e-184 cycA E Amino acid permease
KOBEAFEE_00409 5.1e-57 S Calcineurin-like phosphoesterase
KOBEAFEE_00410 1.9e-53 yutD S Protein of unknown function (DUF1027)
KOBEAFEE_00411 8.3e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KOBEAFEE_00412 1.7e-31 S Protein of unknown function (DUF1461)
KOBEAFEE_00413 1e-92 dedA S SNARE associated Golgi protein
KOBEAFEE_00414 3.6e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KOBEAFEE_00415 8.8e-50 yugI 5.3.1.9 J general stress protein
KOBEAFEE_00425 2.1e-07
KOBEAFEE_00435 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KOBEAFEE_00436 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KOBEAFEE_00437 2.4e-192 cycA E Amino acid permease
KOBEAFEE_00438 1.2e-188 ytgP S Polysaccharide biosynthesis protein
KOBEAFEE_00439 2.8e-62 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KOBEAFEE_00440 2.4e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KOBEAFEE_00441 5.1e-193 pepV 3.5.1.18 E dipeptidase PepV
KOBEAFEE_00442 1.2e-62 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KOBEAFEE_00443 1.5e-67 3.1.21.4 V Type III restriction enzyme res subunit
KOBEAFEE_00444 0.0 L Type III restriction enzyme, res subunit
KOBEAFEE_00446 4e-36
KOBEAFEE_00447 3.4e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KOBEAFEE_00448 4.2e-61 marR K Transcriptional regulator, MarR family
KOBEAFEE_00449 1.4e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KOBEAFEE_00450 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KOBEAFEE_00451 5.5e-103 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KOBEAFEE_00452 2.5e-98 IQ reductase
KOBEAFEE_00453 2.8e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KOBEAFEE_00454 1.7e-46 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KOBEAFEE_00455 3.9e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KOBEAFEE_00456 1.6e-215 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KOBEAFEE_00457 1.2e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KOBEAFEE_00458 1.4e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KOBEAFEE_00459 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KOBEAFEE_00460 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KOBEAFEE_00461 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
KOBEAFEE_00462 5.5e-303 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KOBEAFEE_00463 5.7e-119 gla U Major intrinsic protein
KOBEAFEE_00464 2e-45 ykuL S CBS domain
KOBEAFEE_00465 3.9e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KOBEAFEE_00466 9.2e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KOBEAFEE_00467 9e-87 ykuT M mechanosensitive ion channel
KOBEAFEE_00469 3e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KOBEAFEE_00470 2e-21 yheA S Belongs to the UPF0342 family
KOBEAFEE_00471 8.6e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
KOBEAFEE_00472 2.5e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KOBEAFEE_00474 7e-53 hit FG histidine triad
KOBEAFEE_00475 9.8e-95 ecsA V ABC transporter, ATP-binding protein
KOBEAFEE_00476 1.9e-71 ecsB U ABC transporter
KOBEAFEE_00477 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
KOBEAFEE_00478 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KOBEAFEE_00479 7.5e-44 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KOBEAFEE_00480 6.9e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KOBEAFEE_00483 4.8e-09
KOBEAFEE_00484 5.6e-17 L DnaD domain protein
KOBEAFEE_00491 4.2e-44 S Phage regulatory protein Rha (Phage_pRha)
KOBEAFEE_00492 3.1e-08 S Helix-turn-helix domain
KOBEAFEE_00493 3.7e-07 dicA K Helix-turn-helix domain
KOBEAFEE_00494 3.3e-121 sip L Belongs to the 'phage' integrase family
KOBEAFEE_00495 1.5e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
KOBEAFEE_00496 1.7e-222 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KOBEAFEE_00497 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
KOBEAFEE_00498 8.7e-69 ybhL S Belongs to the BI1 family
KOBEAFEE_00499 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KOBEAFEE_00500 3.3e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KOBEAFEE_00501 1.6e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KOBEAFEE_00502 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KOBEAFEE_00503 1.2e-79 dnaB L replication initiation and membrane attachment
KOBEAFEE_00504 3.3e-108 dnaI L Primosomal protein DnaI
KOBEAFEE_00505 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KOBEAFEE_00506 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KOBEAFEE_00507 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KOBEAFEE_00508 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KOBEAFEE_00509 2.1e-70 yqeG S HAD phosphatase, family IIIA
KOBEAFEE_00510 4.6e-181 yqeH S Ribosome biogenesis GTPase YqeH
KOBEAFEE_00511 6e-30 yhbY J RNA-binding protein
KOBEAFEE_00512 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KOBEAFEE_00513 3e-70 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KOBEAFEE_00514 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KOBEAFEE_00515 5.5e-82 H Nodulation protein S (NodS)
KOBEAFEE_00516 4.5e-123 ylbM S Belongs to the UPF0348 family
KOBEAFEE_00517 8.6e-56 yceD S Uncharacterized ACR, COG1399
KOBEAFEE_00518 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KOBEAFEE_00519 1.2e-88 plsC 2.3.1.51 I Acyltransferase
KOBEAFEE_00520 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
KOBEAFEE_00521 1.5e-27 yazA L GIY-YIG catalytic domain protein
KOBEAFEE_00522 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
KOBEAFEE_00523 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KOBEAFEE_00524 6.9e-37
KOBEAFEE_00525 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KOBEAFEE_00526 3.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KOBEAFEE_00527 1.1e-158 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KOBEAFEE_00528 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KOBEAFEE_00529 7.8e-108 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KOBEAFEE_00531 3.1e-111 K response regulator
KOBEAFEE_00532 2.8e-165 arlS 2.7.13.3 T Histidine kinase
KOBEAFEE_00533 1.6e-97 tnp2 L Transposase
KOBEAFEE_00534 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KOBEAFEE_00535 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KOBEAFEE_00536 1.6e-136 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KOBEAFEE_00537 7.3e-105
KOBEAFEE_00538 3.2e-117
KOBEAFEE_00539 1e-41 dut S dUTPase
KOBEAFEE_00540 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KOBEAFEE_00541 3.7e-46 yqhY S Asp23 family, cell envelope-related function
KOBEAFEE_00542 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KOBEAFEE_00543 3e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KOBEAFEE_00544 5.8e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KOBEAFEE_00545 2.1e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KOBEAFEE_00546 1.2e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KOBEAFEE_00547 5.2e-121 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KOBEAFEE_00548 6.6e-49 argR K Regulates arginine biosynthesis genes
KOBEAFEE_00549 3.8e-179 recN L May be involved in recombinational repair of damaged DNA
KOBEAFEE_00550 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KOBEAFEE_00551 2.2e-30 ynzC S UPF0291 protein
KOBEAFEE_00552 5.9e-27 yneF S UPF0154 protein
KOBEAFEE_00553 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
KOBEAFEE_00554 2.1e-43 MA20_27270 S mazG nucleotide pyrophosphohydrolase
KOBEAFEE_00555 1.6e-97 tnp2 L Transposase
KOBEAFEE_00556 1.2e-74 yciQ P membrane protein (DUF2207)
KOBEAFEE_00557 7.8e-20 D nuclear chromosome segregation
KOBEAFEE_00558 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KOBEAFEE_00559 2.1e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KOBEAFEE_00560 2.8e-69 gluP 3.4.21.105 S Peptidase, S54 family
KOBEAFEE_00561 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
KOBEAFEE_00562 1.5e-156 glk 2.7.1.2 G Glucokinase
KOBEAFEE_00563 2.7e-46 yqhL P Rhodanese-like protein
KOBEAFEE_00564 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
KOBEAFEE_00565 4.2e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KOBEAFEE_00566 3.6e-206 ynbB 4.4.1.1 P aluminum resistance
KOBEAFEE_00567 1.7e-45 glnR K Transcriptional regulator
KOBEAFEE_00568 4.5e-247 glnA 6.3.1.2 E glutamine synthetase
KOBEAFEE_00570 3.4e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KOBEAFEE_00571 2.7e-48 S Domain of unknown function (DUF956)
KOBEAFEE_00572 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KOBEAFEE_00573 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KOBEAFEE_00574 1.1e-104 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KOBEAFEE_00575 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
KOBEAFEE_00576 1.5e-156 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KOBEAFEE_00577 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KOBEAFEE_00578 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KOBEAFEE_00579 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
KOBEAFEE_00580 1.1e-169 nusA K Participates in both transcription termination and antitermination
KOBEAFEE_00581 3.1e-39 ylxR K Protein of unknown function (DUF448)
KOBEAFEE_00582 2.6e-25 ylxQ J ribosomal protein
KOBEAFEE_00583 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KOBEAFEE_00584 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KOBEAFEE_00585 1.1e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KOBEAFEE_00586 6.7e-96 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KOBEAFEE_00587 4.1e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KOBEAFEE_00588 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KOBEAFEE_00589 1.5e-274 dnaK O Heat shock 70 kDa protein
KOBEAFEE_00590 9.2e-161 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KOBEAFEE_00591 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KOBEAFEE_00593 1e-204 glnP P ABC transporter
KOBEAFEE_00594 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KOBEAFEE_00595 4.4e-31
KOBEAFEE_00596 7e-112 ampC V Beta-lactamase
KOBEAFEE_00597 4.6e-110 cobQ S glutamine amidotransferase
KOBEAFEE_00598 1.8e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
KOBEAFEE_00599 6.8e-86 tdk 2.7.1.21 F thymidine kinase
KOBEAFEE_00600 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KOBEAFEE_00601 5.3e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KOBEAFEE_00602 1.7e-134 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KOBEAFEE_00603 1.1e-99 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KOBEAFEE_00604 2.6e-97 atpB C it plays a direct role in the translocation of protons across the membrane
KOBEAFEE_00605 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOBEAFEE_00606 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KOBEAFEE_00607 5.4e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOBEAFEE_00608 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KOBEAFEE_00609 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KOBEAFEE_00610 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KOBEAFEE_00611 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KOBEAFEE_00612 4.1e-15 ywzB S Protein of unknown function (DUF1146)
KOBEAFEE_00613 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KOBEAFEE_00614 3.4e-167 mbl D Cell shape determining protein MreB Mrl
KOBEAFEE_00615 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KOBEAFEE_00616 1.3e-13 S Protein of unknown function (DUF2969)
KOBEAFEE_00617 6.1e-187 rodA D Belongs to the SEDS family
KOBEAFEE_00618 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
KOBEAFEE_00619 3.3e-94 2.7.1.89 M Phosphotransferase enzyme family
KOBEAFEE_00620 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KOBEAFEE_00621 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KOBEAFEE_00622 1.1e-119 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KOBEAFEE_00623 3.2e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KOBEAFEE_00624 4.4e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KOBEAFEE_00625 2e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KOBEAFEE_00626 1.9e-90 stp 3.1.3.16 T phosphatase
KOBEAFEE_00627 1.8e-192 KLT serine threonine protein kinase
KOBEAFEE_00628 8.4e-109 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KOBEAFEE_00629 3.5e-59 thiN 2.7.6.2 H thiamine pyrophosphokinase
KOBEAFEE_00630 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KOBEAFEE_00631 4.5e-53 asp S Asp23 family, cell envelope-related function
KOBEAFEE_00632 4.3e-239 yloV S DAK2 domain fusion protein YloV
KOBEAFEE_00633 7.5e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KOBEAFEE_00634 2.1e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KOBEAFEE_00635 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KOBEAFEE_00636 3.9e-101 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KOBEAFEE_00637 2.6e-214 smc D Required for chromosome condensation and partitioning
KOBEAFEE_00638 1.5e-148 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KOBEAFEE_00639 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KOBEAFEE_00640 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KOBEAFEE_00641 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KOBEAFEE_00642 1.1e-26 ylqC S Belongs to the UPF0109 family
KOBEAFEE_00643 7.2e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KOBEAFEE_00644 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KOBEAFEE_00645 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
KOBEAFEE_00646 1.1e-198 yfnA E amino acid
KOBEAFEE_00647 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KOBEAFEE_00648 8.7e-204 L Belongs to the 'phage' integrase family
KOBEAFEE_00651 4.9e-34 D Anion-transporting ATPase
KOBEAFEE_00653 7.6e-28 E Zn peptidase
KOBEAFEE_00654 4.1e-24 xre K Helix-turn-helix domain
KOBEAFEE_00660 2.6e-08 K Helix-turn-helix XRE-family like proteins
KOBEAFEE_00661 7.5e-84 ps308 K AntA/AntB antirepressor
KOBEAFEE_00668 3.6e-54 S Putative HNHc nuclease
KOBEAFEE_00669 6.4e-30 S Phage replisome organizer, N-terminal domain protein
KOBEAFEE_00672 2.1e-25
KOBEAFEE_00673 1.8e-69
KOBEAFEE_00689 1.8e-25 arpU S Phage transcriptional regulator, ArpU family
KOBEAFEE_00691 4.6e-21
KOBEAFEE_00692 4.4e-88 L HNH nucleases
KOBEAFEE_00693 4.3e-83 L Phage terminase, small subunit
KOBEAFEE_00694 0.0 S Phage Terminase
KOBEAFEE_00696 9.9e-219 S Phage portal protein
KOBEAFEE_00697 3.8e-120 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
KOBEAFEE_00698 3.4e-222 S Phage capsid family
KOBEAFEE_00699 1.8e-21 S Phage gp6-like head-tail connector protein
KOBEAFEE_00700 2.7e-58 S Phage head-tail joining protein
KOBEAFEE_00701 2.5e-65 S Bacteriophage HK97-gp10, putative tail-component
KOBEAFEE_00702 1.2e-64 S Protein of unknown function (DUF806)
KOBEAFEE_00703 3.2e-124 S Phage tail tube protein
KOBEAFEE_00704 6.3e-54 S Phage tail assembly chaperone proteins, TAC
KOBEAFEE_00706 0.0 M Phage tail tape measure protein TP901
KOBEAFEE_00707 1e-124 S Phage tail protein
KOBEAFEE_00708 5.9e-282 rny D peptidase
KOBEAFEE_00711 9.7e-72 S Domain of unknown function (DUF2479)
KOBEAFEE_00715 7.7e-21 S Bacteriophage holin of superfamily 6 (Holin_LLH)
KOBEAFEE_00716 3.5e-126 M Glycosyl hydrolases family 25
KOBEAFEE_00717 2e-22
KOBEAFEE_00718 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
KOBEAFEE_00719 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KOBEAFEE_00720 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KOBEAFEE_00721 4.9e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KOBEAFEE_00722 1.2e-17 S Tetratricopeptide repeat
KOBEAFEE_00723 8e-216 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KOBEAFEE_00724 5e-195 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KOBEAFEE_00725 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KOBEAFEE_00726 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KOBEAFEE_00727 1.9e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KOBEAFEE_00728 5e-23 ykzG S Belongs to the UPF0356 family
KOBEAFEE_00729 5.5e-25
KOBEAFEE_00730 8.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KOBEAFEE_00731 2.4e-31 1.1.1.27 C L-malate dehydrogenase activity
KOBEAFEE_00732 9.8e-24 yktA S Belongs to the UPF0223 family
KOBEAFEE_00733 2.8e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KOBEAFEE_00734 0.0 typA T GTP-binding protein TypA
KOBEAFEE_00735 1.6e-97 tnp2 L Transposase
KOBEAFEE_00736 4.6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
KOBEAFEE_00737 1.6e-114 manY G PTS system
KOBEAFEE_00738 3.3e-148 manN G system, mannose fructose sorbose family IID component
KOBEAFEE_00739 2.5e-100 ftsW D Belongs to the SEDS family
KOBEAFEE_00740 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KOBEAFEE_00741 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
KOBEAFEE_00742 1.2e-73 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KOBEAFEE_00743 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KOBEAFEE_00744 2.4e-131 ylbL T Belongs to the peptidase S16 family
KOBEAFEE_00745 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KOBEAFEE_00746 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KOBEAFEE_00747 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KOBEAFEE_00748 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KOBEAFEE_00749 2.7e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KOBEAFEE_00750 1.5e-138 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KOBEAFEE_00751 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KOBEAFEE_00752 1.1e-233 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KOBEAFEE_00753 1.4e-162 purD 6.3.4.13 F Belongs to the GARS family
KOBEAFEE_00754 3e-70 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KOBEAFEE_00755 9.1e-155 S Dynamin family
KOBEAFEE_00756 5.9e-09
KOBEAFEE_00757 1.3e-21
KOBEAFEE_00758 0.0 S Domain of unknown function DUF87
KOBEAFEE_00759 7.3e-45 S nuclease activity
KOBEAFEE_00760 5.9e-109 S Acyltransferase family
KOBEAFEE_00761 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KOBEAFEE_00762 6.6e-122 K LysR substrate binding domain
KOBEAFEE_00764 2.2e-20
KOBEAFEE_00765 4.7e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KOBEAFEE_00766 3.4e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
KOBEAFEE_00767 4e-50 comEA L Competence protein ComEA
KOBEAFEE_00768 2e-69 comEB 3.5.4.12 F ComE operon protein 2
KOBEAFEE_00769 3.6e-156 comEC S Competence protein ComEC
KOBEAFEE_00770 2.7e-103 holA 2.7.7.7 L DNA polymerase III delta subunit
KOBEAFEE_00771 6.6e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KOBEAFEE_00772 5.6e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KOBEAFEE_00773 2.2e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KOBEAFEE_00774 5.2e-93 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KOBEAFEE_00775 8.7e-229 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KOBEAFEE_00776 3.8e-34 ypmB S Protein conserved in bacteria
KOBEAFEE_00777 3.4e-142 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KOBEAFEE_00778 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KOBEAFEE_00779 1.9e-55 dnaD L DnaD domain protein
KOBEAFEE_00780 2.2e-82 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KOBEAFEE_00781 7.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KOBEAFEE_00782 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KOBEAFEE_00783 4.3e-93 M transferase activity, transferring glycosyl groups
KOBEAFEE_00784 4.9e-84 M Glycosyltransferase sugar-binding region containing DXD motif
KOBEAFEE_00785 5.8e-100 epsJ1 M Glycosyltransferase like family 2
KOBEAFEE_00788 3.2e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KOBEAFEE_00789 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KOBEAFEE_00790 7e-56 yqeY S YqeY-like protein
KOBEAFEE_00791 3e-68 xerD L Phage integrase, N-terminal SAM-like domain
KOBEAFEE_00792 1.3e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KOBEAFEE_00793 8.2e-108 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KOBEAFEE_00794 3.9e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KOBEAFEE_00795 1.4e-275 yfmR S ABC transporter, ATP-binding protein
KOBEAFEE_00796 1.3e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KOBEAFEE_00797 7.9e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KOBEAFEE_00799 1.7e-80 ypmR E GDSL-like Lipase/Acylhydrolase
KOBEAFEE_00800 4.4e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
KOBEAFEE_00801 6.2e-24 yozE S Belongs to the UPF0346 family
KOBEAFEE_00802 1.2e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KOBEAFEE_00803 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOBEAFEE_00804 3.7e-85 dprA LU DNA protecting protein DprA
KOBEAFEE_00805 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KOBEAFEE_00806 9.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KOBEAFEE_00807 1.7e-204 G PTS system Galactitol-specific IIC component
KOBEAFEE_00808 4.7e-153 M Exporter of polyketide antibiotics
KOBEAFEE_00809 4.7e-101 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KOBEAFEE_00810 1e-34 S Repeat protein
KOBEAFEE_00811 5.3e-278 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KOBEAFEE_00813 5.4e-32 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KOBEAFEE_00814 1.3e-78 S Dynamin family
KOBEAFEE_00815 3e-11
KOBEAFEE_00819 2.2e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOBEAFEE_00820 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KOBEAFEE_00821 9.1e-43 yodB K Transcriptional regulator, HxlR family
KOBEAFEE_00822 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KOBEAFEE_00823 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KOBEAFEE_00824 1.6e-128 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KOBEAFEE_00825 3.1e-97 udk 2.7.1.48 F Cytidine monophosphokinase
KOBEAFEE_00826 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KOBEAFEE_00827 6.4e-12
KOBEAFEE_00828 3.9e-144 iunH2 3.2.2.1 F nucleoside hydrolase
KOBEAFEE_00829 1.7e-42 XK27_03960 S Protein of unknown function (DUF3013)
KOBEAFEE_00830 3.4e-118 prmA J Ribosomal protein L11 methyltransferase
KOBEAFEE_00831 6.3e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KOBEAFEE_00832 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KOBEAFEE_00833 3.9e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KOBEAFEE_00834 5.1e-57 3.1.3.18 J HAD-hyrolase-like
KOBEAFEE_00835 3.4e-42 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KOBEAFEE_00836 9.6e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KOBEAFEE_00837 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KOBEAFEE_00838 5.4e-205 pyrP F Permease
KOBEAFEE_00839 3.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KOBEAFEE_00840 7.7e-192 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KOBEAFEE_00841 8.8e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KOBEAFEE_00842 2.3e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KOBEAFEE_00843 3.7e-134 K Transcriptional regulator
KOBEAFEE_00844 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
KOBEAFEE_00845 8.6e-115 glcR K DeoR C terminal sensor domain
KOBEAFEE_00846 1.2e-171 patA 2.6.1.1 E Aminotransferase
KOBEAFEE_00847 1.2e-87 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KOBEAFEE_00849 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KOBEAFEE_00850 3e-172 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KOBEAFEE_00851 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
KOBEAFEE_00852 1.5e-22 S Family of unknown function (DUF5322)
KOBEAFEE_00853 5.9e-257 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KOBEAFEE_00854 8e-39
KOBEAFEE_00856 5.6e-13 D nuclear chromosome segregation
KOBEAFEE_00857 8.7e-150 EGP Sugar (and other) transporter
KOBEAFEE_00858 7.8e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
KOBEAFEE_00859 1.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KOBEAFEE_00860 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KOBEAFEE_00861 5.7e-70 alkD L DNA alkylation repair enzyme
KOBEAFEE_00862 4.2e-135 EG EamA-like transporter family
KOBEAFEE_00863 2.8e-150 S Tetratricopeptide repeat protein
KOBEAFEE_00864 5.3e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
KOBEAFEE_00865 1.5e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KOBEAFEE_00866 2.7e-126 corA P CorA-like Mg2+ transporter protein
KOBEAFEE_00867 4.2e-160 nhaC C Na H antiporter NhaC
KOBEAFEE_00868 1.6e-129 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KOBEAFEE_00869 2.6e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KOBEAFEE_00871 1.9e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KOBEAFEE_00872 1.5e-158 iscS 2.8.1.7 E Aminotransferase class V
KOBEAFEE_00873 3.7e-41 XK27_04120 S Putative amino acid metabolism
KOBEAFEE_00874 7.4e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KOBEAFEE_00875 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KOBEAFEE_00876 5.6e-15 S Protein of unknown function (DUF2929)
KOBEAFEE_00877 0.0 dnaE 2.7.7.7 L DNA polymerase
KOBEAFEE_00878 1.5e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KOBEAFEE_00879 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KOBEAFEE_00881 1e-39 ypaA S Protein of unknown function (DUF1304)
KOBEAFEE_00882 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KOBEAFEE_00883 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KOBEAFEE_00884 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KOBEAFEE_00885 1.6e-97 tnp2 L Transposase
KOBEAFEE_00886 1.4e-202 FbpA K Fibronectin-binding protein
KOBEAFEE_00887 3.1e-40 K Transcriptional regulator
KOBEAFEE_00888 3.1e-116 degV S EDD domain protein, DegV family
KOBEAFEE_00889 4.8e-71 lepB 3.4.21.89 U Signal peptidase, peptidase S26
KOBEAFEE_00890 5.7e-188 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KOBEAFEE_00892 3.3e-111 M lysozyme activity
KOBEAFEE_00893 2e-19 S Bacteriophage holin of superfamily 6 (Holin_LLH)
KOBEAFEE_00896 5.3e-61 S Prophage endopeptidase tail
KOBEAFEE_00897 1.2e-33 S phage tail
KOBEAFEE_00898 1.8e-156 M Phage tail tape measure protein TP901
KOBEAFEE_00900 1.2e-18
KOBEAFEE_00901 5.5e-64
KOBEAFEE_00902 2.7e-33
KOBEAFEE_00903 1.8e-25 S Bacteriophage HK97-gp10, putative tail-component
KOBEAFEE_00904 2e-14 S Phage head-tail joining protein
KOBEAFEE_00905 5.7e-20 S Phage gp6-like head-tail connector protein
KOBEAFEE_00906 5e-111 S peptidase activity
KOBEAFEE_00907 1.5e-64 pi136 S Caudovirus prohead serine protease
KOBEAFEE_00908 5.9e-153 S Phage portal protein
KOBEAFEE_00909 4.6e-289 terL S overlaps another CDS with the same product name
KOBEAFEE_00910 9.7e-53 terS L Phage terminase, small subunit
KOBEAFEE_00911 2.6e-61 L HNH nucleases
KOBEAFEE_00915 5.1e-22 radC L DNA repair protein
KOBEAFEE_00920 3.4e-17 arpU S Phage transcriptional regulator, ArpU family
KOBEAFEE_00938 7.2e-66
KOBEAFEE_00939 2.7e-25
KOBEAFEE_00942 6.4e-30 L N-terminal phage replisome organiser (Phage_rep_org_N)
KOBEAFEE_00943 3.6e-54 S Putative HNHc nuclease
KOBEAFEE_00949 6e-81 ps308 K AntA/AntB antirepressor
KOBEAFEE_00950 2.9e-09 XK27_07105 K Helix-turn-helix XRE-family like proteins
KOBEAFEE_00951 1.4e-37 K Helix-turn-helix XRE-family like proteins
KOBEAFEE_00952 4.9e-38 E Zn peptidase
KOBEAFEE_00954 1.8e-19
KOBEAFEE_00955 3.7e-85 sip L Belongs to the 'phage' integrase family
KOBEAFEE_00956 8.3e-71 yjjH S Calcineurin-like phosphoesterase
KOBEAFEE_00957 1.8e-95 EG EamA-like transporter family
KOBEAFEE_00958 1.5e-84 natB CP ABC-type Na efflux pump, permease component
KOBEAFEE_00959 6.2e-112 natA S Domain of unknown function (DUF4162)
KOBEAFEE_00960 5.3e-22 K Acetyltransferase (GNAT) domain
KOBEAFEE_00962 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KOBEAFEE_00963 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KOBEAFEE_00964 1e-170 rpsA 1.17.7.4 J Ribosomal protein S1
KOBEAFEE_00965 9.1e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
KOBEAFEE_00966 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KOBEAFEE_00967 1.4e-28 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOBEAFEE_00968 5.3e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
KOBEAFEE_00969 1e-218 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOBEAFEE_00970 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
KOBEAFEE_00971 6.9e-91 recO L Involved in DNA repair and RecF pathway recombination
KOBEAFEE_00972 3.5e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KOBEAFEE_00973 4.7e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KOBEAFEE_00974 5.6e-67 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KOBEAFEE_00975 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
KOBEAFEE_00976 1.8e-129 S Uncharacterised protein family (UPF0236)
KOBEAFEE_00979 1e-56 M Peptidase family M23
KOBEAFEE_00981 8.4e-287 U type IV secretory pathway VirB4
KOBEAFEE_00982 5.3e-65
KOBEAFEE_00986 2.4e-15 S HicB family
KOBEAFEE_00987 7.5e-18 hicA S HicA toxin of bacterial toxin-antitoxin,
KOBEAFEE_00996 1.4e-16
KOBEAFEE_00997 5e-28 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KOBEAFEE_00999 7.9e-130 NU StbA protein
KOBEAFEE_01000 1.1e-10
KOBEAFEE_01002 8.4e-29 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KOBEAFEE_01012 6.8e-25 radC E Belongs to the UPF0758 family
KOBEAFEE_01013 2e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KOBEAFEE_01021 1.6e-97 tnp2 L Transposase
KOBEAFEE_01022 1.1e-14 S Bacterial toxin of type II toxin-antitoxin system, YafQ
KOBEAFEE_01023 1.3e-14
KOBEAFEE_01024 4.4e-303
KOBEAFEE_01025 4.9e-128 3.1.21.4 L Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1
KOBEAFEE_01026 3.3e-94 dam 2.1.1.72 L Site-specific DNA-methyltransferase (Adenine-specific)
KOBEAFEE_01027 2.3e-08 XK27_10540 S ParE toxin of type II toxin-antitoxin system, parDE
KOBEAFEE_01028 7.6e-09 D Antitoxin component of a toxin-antitoxin (TA) module
KOBEAFEE_01032 5.7e-46 3.4.22.70 M Sortase family
KOBEAFEE_01033 1.2e-87 M Gram-positive pilin backbone subunit 2, Cna-B-like domain
KOBEAFEE_01034 3.6e-27 3.4.22.70 M Sortase family
KOBEAFEE_01042 1.5e-22 D nuclear chromosome segregation
KOBEAFEE_01044 1.7e-21 K Cro/C1-type HTH DNA-binding domain
KOBEAFEE_01045 2.6e-11 S BRCA1 C Terminus (BRCT) domain
KOBEAFEE_01046 1.1e-105
KOBEAFEE_01047 8.9e-235 U COG3505 Type IV secretory pathway, VirD4 components
KOBEAFEE_01048 1.6e-10
KOBEAFEE_01050 4.6e-194 clpB O Belongs to the ClpA ClpB family
KOBEAFEE_01053 8.8e-218 L Probable transposase
KOBEAFEE_01054 1.1e-109 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KOBEAFEE_01055 3.7e-60 traI 5.99.1.2 L C-terminal repeat of topoisomerase
KOBEAFEE_01057 3.4e-73 L Protein of unknown function (DUF3991)
KOBEAFEE_01058 1.5e-120 ruvB 3.6.4.12 L four-way junction helicase activity
KOBEAFEE_01059 3.7e-12
KOBEAFEE_01062 6.5e-07
KOBEAFEE_01063 1.4e-67 ada 3.2.2.21 F DNA/RNA non-specific endonuclease
KOBEAFEE_01067 4.1e-32
KOBEAFEE_01071 3.4e-13 S Thioredoxin
KOBEAFEE_01072 5.8e-10
KOBEAFEE_01076 3.4e-115 repE K Primase C terminal 1 (PriCT-1)
KOBEAFEE_01077 4.4e-83 lytH 3.5.1.28 M Ami_3
KOBEAFEE_01078 1.7e-85 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KOBEAFEE_01079 3.8e-11 M Lysin motif
KOBEAFEE_01080 3.8e-127 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KOBEAFEE_01081 3.8e-60 ypbB 5.1.3.1 S Helix-turn-helix domain
KOBEAFEE_01082 6.4e-221 mntH P H( )-stimulated, divalent metal cation uptake system
KOBEAFEE_01083 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KOBEAFEE_01084 1.2e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KOBEAFEE_01085 9.6e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KOBEAFEE_01086 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KOBEAFEE_01087 4.4e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
KOBEAFEE_01088 7.4e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOBEAFEE_01089 1.2e-78 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
KOBEAFEE_01090 1.3e-84 3.1.21.3 V Type I restriction modification DNA specificity domain
KOBEAFEE_01091 6.1e-131 L Belongs to the 'phage' integrase family
KOBEAFEE_01092 1.4e-76 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
KOBEAFEE_01093 1e-202 hsdM 2.1.1.72 V type I restriction-modification system
KOBEAFEE_01094 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
KOBEAFEE_01096 3.9e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
KOBEAFEE_01097 2.8e-56 3.6.1.27 I Acid phosphatase homologues
KOBEAFEE_01098 1.8e-68 maa 2.3.1.79 S Maltose acetyltransferase
KOBEAFEE_01099 1.4e-75 2.3.1.178 M GNAT acetyltransferase
KOBEAFEE_01101 8.4e-198 ade 3.5.4.2 F Adenine deaminase C-terminal domain
KOBEAFEE_01102 7.8e-65 ypsA S Belongs to the UPF0398 family
KOBEAFEE_01103 3.7e-188 nhaC C Na H antiporter NhaC
KOBEAFEE_01104 2.3e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KOBEAFEE_01105 1.9e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KOBEAFEE_01106 5.5e-113 xerD D recombinase XerD
KOBEAFEE_01107 9.6e-126 cvfB S S1 domain
KOBEAFEE_01108 4.1e-51 yeaL S Protein of unknown function (DUF441)
KOBEAFEE_01109 3.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KOBEAFEE_01110 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KOBEAFEE_01111 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KOBEAFEE_01112 1.2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KOBEAFEE_01113 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOBEAFEE_01114 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KOBEAFEE_01115 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KOBEAFEE_01116 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
KOBEAFEE_01117 1.3e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KOBEAFEE_01118 1.7e-102 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KOBEAFEE_01119 1.6e-97 tnp2 L Transposase
KOBEAFEE_01120 2.6e-70
KOBEAFEE_01124 1.6e-12
KOBEAFEE_01125 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KOBEAFEE_01126 1e-27 ysxB J Cysteine protease Prp
KOBEAFEE_01127 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
KOBEAFEE_01131 2.2e-08 S Protein of unknown function (DUF2922)
KOBEAFEE_01133 6.4e-16 K DNA-templated transcription, initiation
KOBEAFEE_01135 3e-67 H Methyltransferase domain
KOBEAFEE_01136 1.4e-17 galE 5.1.3.2 M GDP-mannose 4,6 dehydratase
KOBEAFEE_01137 4.4e-08 cps2D 5.1.3.2 M RmlD substrate binding domain
KOBEAFEE_01138 5.4e-20 cps2D 5.1.3.2 M RmlD substrate binding domain
KOBEAFEE_01139 1.3e-40 wecD M Acetyltransferase (GNAT) family
KOBEAFEE_01141 7.3e-27 ybl78 L Conserved phage C-terminus (Phg_2220_C)
KOBEAFEE_01143 0.0 LV site-specific DNA-methyltransferase (adenine-specific) activity
KOBEAFEE_01144 6.3e-85 L Restriction endonuclease
KOBEAFEE_01145 3.6e-66 1.1.1.1 C Zinc-binding dehydrogenase
KOBEAFEE_01146 7.8e-09 1.1.1.1 C Zinc-binding dehydrogenase
KOBEAFEE_01147 3.7e-32 S CHY zinc finger
KOBEAFEE_01148 9.5e-40 K Transcriptional regulator
KOBEAFEE_01149 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
KOBEAFEE_01151 2.7e-43 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
KOBEAFEE_01152 2.2e-180 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KOBEAFEE_01153 4.8e-81
KOBEAFEE_01154 2.4e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KOBEAFEE_01155 1.8e-113 yitU 3.1.3.104 S hydrolase
KOBEAFEE_01156 2.5e-60 speG J Acetyltransferase (GNAT) domain
KOBEAFEE_01157 3.1e-189 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KOBEAFEE_01158 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KOBEAFEE_01159 2.2e-204 pipD E Dipeptidase
KOBEAFEE_01160 2.3e-45
KOBEAFEE_01161 3.5e-64 K helix_turn_helix, arabinose operon control protein
KOBEAFEE_01162 2.6e-53 S Membrane
KOBEAFEE_01163 0.0 rafA 3.2.1.22 G alpha-galactosidase
KOBEAFEE_01164 3.2e-78 L Helicase C-terminal domain protein
KOBEAFEE_01165 3.3e-146 pbuO_1 S Permease family
KOBEAFEE_01166 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
KOBEAFEE_01167 1.2e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KOBEAFEE_01168 6.2e-97 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KOBEAFEE_01169 8e-220 cydD CO ABC transporter transmembrane region
KOBEAFEE_01170 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KOBEAFEE_01171 5.6e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
KOBEAFEE_01172 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
KOBEAFEE_01173 3.1e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
KOBEAFEE_01174 1.5e-26 xlyB 3.5.1.28 CBM50 M LysM domain
KOBEAFEE_01175 2.3e-19 glpE P Rhodanese Homology Domain
KOBEAFEE_01176 6e-48 lytE M LysM domain protein
KOBEAFEE_01177 4.8e-93 T Calcineurin-like phosphoesterase superfamily domain
KOBEAFEE_01178 5.1e-86 2.7.7.12 C Domain of unknown function (DUF4931)
KOBEAFEE_01180 9.7e-74 draG O ADP-ribosylglycohydrolase
KOBEAFEE_01181 1.6e-101 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KOBEAFEE_01182 1.6e-97 tnp2 L Transposase
KOBEAFEE_01184 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KOBEAFEE_01185 5.1e-62 divIVA D DivIVA domain protein
KOBEAFEE_01186 3.5e-82 ylmH S S4 domain protein
KOBEAFEE_01187 3e-19 yggT S YGGT family
KOBEAFEE_01188 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KOBEAFEE_01189 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KOBEAFEE_01190 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KOBEAFEE_01191 1.9e-62 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KOBEAFEE_01192 2.3e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KOBEAFEE_01193 7.7e-186 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KOBEAFEE_01194 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KOBEAFEE_01195 2e-281 ftsI 3.4.16.4 M Penicillin-binding Protein
KOBEAFEE_01196 2.5e-11 ftsL D cell division protein FtsL
KOBEAFEE_01197 3e-141 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KOBEAFEE_01198 5.2e-64 mraZ K Belongs to the MraZ family
KOBEAFEE_01199 5.8e-08 S Protein of unknown function (DUF3397)
KOBEAFEE_01200 1.4e-156 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
KOBEAFEE_01201 4.8e-99 D Alpha beta
KOBEAFEE_01202 1.8e-108 aatB ET ABC transporter substrate-binding protein
KOBEAFEE_01203 1.4e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KOBEAFEE_01204 7.2e-94 glnP P ABC transporter permease
KOBEAFEE_01205 1.8e-126 minD D Belongs to the ParA family
KOBEAFEE_01206 1.4e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KOBEAFEE_01207 1.2e-54 mreD M rod shape-determining protein MreD
KOBEAFEE_01208 2.1e-88 mreC M Involved in formation and maintenance of cell shape
KOBEAFEE_01209 1.8e-155 mreB D cell shape determining protein MreB
KOBEAFEE_01210 4.5e-21 K Cold shock
KOBEAFEE_01211 6.2e-80 radC L DNA repair protein
KOBEAFEE_01212 8.1e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KOBEAFEE_01213 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KOBEAFEE_01214 2.5e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KOBEAFEE_01215 3.8e-162 iscS2 2.8.1.7 E Aminotransferase class V
KOBEAFEE_01216 1.2e-172 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KOBEAFEE_01217 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
KOBEAFEE_01218 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KOBEAFEE_01219 3.4e-24 yueI S Protein of unknown function (DUF1694)
KOBEAFEE_01220 3.4e-188 rarA L recombination factor protein RarA
KOBEAFEE_01222 3.2e-73 usp6 T universal stress protein
KOBEAFEE_01223 1.8e-53 tag 3.2.2.20 L glycosylase
KOBEAFEE_01224 7.7e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KOBEAFEE_01225 7.7e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KOBEAFEE_01226 4e-96 tnp2 L Transposase
KOBEAFEE_01227 2.2e-35 K Psort location Cytoplasmic, score 8.87
KOBEAFEE_01228 2.2e-124 O regulation of methylation-dependent chromatin silencing
KOBEAFEE_01229 4.5e-22 K Cro/C1-type HTH DNA-binding domain
KOBEAFEE_01230 1.6e-19 ebh D nuclear chromosome segregation
KOBEAFEE_01232 4.4e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
KOBEAFEE_01233 6e-296 S membrane
KOBEAFEE_01234 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KOBEAFEE_01235 6.8e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
KOBEAFEE_01236 6.9e-102 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
KOBEAFEE_01237 1.2e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KOBEAFEE_01239 1.4e-16
KOBEAFEE_01240 1.6e-202 oatA I Acyltransferase
KOBEAFEE_01241 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KOBEAFEE_01242 1.6e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KOBEAFEE_01243 4.4e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOBEAFEE_01246 1.5e-41 S Phosphoesterase
KOBEAFEE_01247 2.5e-72 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KOBEAFEE_01248 1.4e-60 yslB S Protein of unknown function (DUF2507)
KOBEAFEE_01249 1.1e-14 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KOBEAFEE_01250 1.4e-92 RB5993 3.1.1.3 I Pfam Lipase (class 3)
KOBEAFEE_01251 7.6e-41 trxA O Belongs to the thioredoxin family
KOBEAFEE_01252 3.9e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KOBEAFEE_01253 1.6e-17 cvpA S Colicin V production protein
KOBEAFEE_01254 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KOBEAFEE_01255 1.1e-33 yrzB S Belongs to the UPF0473 family
KOBEAFEE_01256 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KOBEAFEE_01257 2.1e-36 yrzL S Belongs to the UPF0297 family
KOBEAFEE_01258 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KOBEAFEE_01259 1.9e-186 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KOBEAFEE_01260 5.5e-122 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KOBEAFEE_01261 7.5e-13
KOBEAFEE_01262 2.1e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KOBEAFEE_01263 1.2e-65 yrjD S LUD domain
KOBEAFEE_01264 2.1e-245 lutB C 4Fe-4S dicluster domain
KOBEAFEE_01265 6.9e-117 lutA C Cysteine-rich domain
KOBEAFEE_01266 9.7e-208 yfnA E Amino Acid
KOBEAFEE_01268 4.3e-61 uspA T universal stress protein
KOBEAFEE_01270 1.8e-12 yajC U Preprotein translocase
KOBEAFEE_01271 7.8e-208 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KOBEAFEE_01272 7.9e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KOBEAFEE_01273 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KOBEAFEE_01274 4.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KOBEAFEE_01275 1.3e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KOBEAFEE_01276 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KOBEAFEE_01277 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
KOBEAFEE_01278 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KOBEAFEE_01279 4.7e-84 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KOBEAFEE_01280 1.1e-63 ymfM S Helix-turn-helix domain
KOBEAFEE_01281 6.4e-91 IQ Enoyl-(Acyl carrier protein) reductase
KOBEAFEE_01282 2.4e-149 ymfH S Peptidase M16
KOBEAFEE_01283 7e-109 ymfF S Peptidase M16 inactive domain protein
KOBEAFEE_01284 1.6e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
KOBEAFEE_01285 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KOBEAFEE_01286 3.4e-99 rrmA 2.1.1.187 H Methyltransferase
KOBEAFEE_01287 1.1e-60 ybaK J Aminoacyl-tRNA editing domain
KOBEAFEE_01288 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KOBEAFEE_01289 1.4e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KOBEAFEE_01290 1.6e-97 tnp2 L Transposase
KOBEAFEE_01291 7.1e-21 cutC P Participates in the control of copper homeostasis
KOBEAFEE_01292 1.5e-130 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KOBEAFEE_01293 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KOBEAFEE_01294 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KOBEAFEE_01295 5.3e-68 ybbR S YbbR-like protein
KOBEAFEE_01296 2.9e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KOBEAFEE_01297 2.4e-71 S Protein of unknown function (DUF1361)
KOBEAFEE_01298 1.2e-115 murB 1.3.1.98 M Cell wall formation
KOBEAFEE_01299 2.3e-69 dnaQ 2.7.7.7 L DNA polymerase III
KOBEAFEE_01300 3.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KOBEAFEE_01301 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KOBEAFEE_01302 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KOBEAFEE_01303 6.3e-117 ycsE S Sucrose-6F-phosphate phosphohydrolase
KOBEAFEE_01304 2e-41 yxjI
KOBEAFEE_01305 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KOBEAFEE_01306 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KOBEAFEE_01307 2.8e-19 secG U Preprotein translocase
KOBEAFEE_01308 7e-180 clcA P chloride
KOBEAFEE_01309 3.5e-147 lmrP E Major Facilitator Superfamily
KOBEAFEE_01310 1.8e-169 T PhoQ Sensor
KOBEAFEE_01311 1.9e-103 K response regulator
KOBEAFEE_01312 1.1e-131 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KOBEAFEE_01313 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KOBEAFEE_01314 2.6e-127 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KOBEAFEE_01315 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KOBEAFEE_01316 2.9e-174 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KOBEAFEE_01317 2.1e-135 cggR K Putative sugar-binding domain
KOBEAFEE_01319 1.2e-98 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KOBEAFEE_01320 1.8e-149 whiA K May be required for sporulation
KOBEAFEE_01321 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KOBEAFEE_01322 7.5e-126 rapZ S Displays ATPase and GTPase activities
KOBEAFEE_01323 2.2e-79 ylbE GM NAD dependent epimerase dehydratase family protein
KOBEAFEE_01324 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KOBEAFEE_01325 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KOBEAFEE_01326 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KOBEAFEE_01327 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KOBEAFEE_01328 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KOBEAFEE_01329 1.3e-131 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KOBEAFEE_01330 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KOBEAFEE_01331 4.1e-08 KT PspC domain protein
KOBEAFEE_01332 1.5e-85 phoR 2.7.13.3 T Histidine kinase
KOBEAFEE_01333 3.5e-86 K response regulator
KOBEAFEE_01334 4.5e-67 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
KOBEAFEE_01335 1.9e-163 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KOBEAFEE_01336 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KOBEAFEE_01337 7e-95 yeaN P Major Facilitator Superfamily
KOBEAFEE_01338 2.7e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KOBEAFEE_01339 1.6e-51 comFC S Competence protein
KOBEAFEE_01340 1.6e-127 comFA L Helicase C-terminal domain protein
KOBEAFEE_01341 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
KOBEAFEE_01342 6.4e-297 ydaO E amino acid
KOBEAFEE_01343 1.3e-268 aha1 P COG COG0474 Cation transport ATPase
KOBEAFEE_01344 1.3e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KOBEAFEE_01345 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KOBEAFEE_01346 1.2e-32 S CAAX protease self-immunity
KOBEAFEE_01347 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KOBEAFEE_01348 1e-255 uup S ABC transporter, ATP-binding protein
KOBEAFEE_01349 1.1e-160 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KOBEAFEE_01350 2.5e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KOBEAFEE_01351 3.1e-69 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KOBEAFEE_01352 3.5e-140 ansA 3.5.1.1 EJ Asparaginase
KOBEAFEE_01353 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
KOBEAFEE_01354 1.6e-91 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KOBEAFEE_01355 1.4e-40 yabA L Involved in initiation control of chromosome replication
KOBEAFEE_01356 3e-83 holB 2.7.7.7 L DNA polymerase III
KOBEAFEE_01357 1.1e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KOBEAFEE_01358 7.1e-29 yaaL S Protein of unknown function (DUF2508)
KOBEAFEE_01359 8.4e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KOBEAFEE_01360 1.4e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KOBEAFEE_01361 7.9e-212 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KOBEAFEE_01362 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KOBEAFEE_01363 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
KOBEAFEE_01364 1.2e-27 nrdH O Glutaredoxin
KOBEAFEE_01365 4.8e-45 nrdI F NrdI Flavodoxin like
KOBEAFEE_01366 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOBEAFEE_01367 5.2e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOBEAFEE_01368 1.6e-97 tnp2 L Transposase
KOBEAFEE_01369 9.3e-302 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KOBEAFEE_01370 1.6e-55
KOBEAFEE_01371 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KOBEAFEE_01372 1.7e-74 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KOBEAFEE_01373 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KOBEAFEE_01374 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KOBEAFEE_01375 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
KOBEAFEE_01376 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KOBEAFEE_01377 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KOBEAFEE_01378 2.1e-70 yacP S YacP-like NYN domain
KOBEAFEE_01379 3.2e-109 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOBEAFEE_01380 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KOBEAFEE_01381 4e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KOBEAFEE_01382 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KOBEAFEE_01383 8.2e-154 yacL S domain protein
KOBEAFEE_01384 3.5e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KOBEAFEE_01385 9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KOBEAFEE_01386 1.2e-18 HA62_12640 S GCN5-related N-acetyl-transferase
KOBEAFEE_01387 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
KOBEAFEE_01388 1e-33 S Enterocin A Immunity
KOBEAFEE_01389 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KOBEAFEE_01390 1e-128 mleP2 S Sodium Bile acid symporter family
KOBEAFEE_01391 6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KOBEAFEE_01393 1.5e-42 ydcK S Belongs to the SprT family
KOBEAFEE_01394 3.7e-251 yhgF K Tex-like protein N-terminal domain protein
KOBEAFEE_01395 2.3e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KOBEAFEE_01396 7.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KOBEAFEE_01397 3.6e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KOBEAFEE_01398 6.4e-96 gntR1 K UbiC transcription regulator-associated domain protein
KOBEAFEE_01399 1e-89 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KOBEAFEE_01401 1.1e-07
KOBEAFEE_01402 1.6e-197 dtpT U amino acid peptide transporter
KOBEAFEE_01404 2.5e-92 yihY S Belongs to the UPF0761 family
KOBEAFEE_01405 1.5e-10 mltD CBM50 M Lysin motif
KOBEAFEE_01406 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KOBEAFEE_01407 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
KOBEAFEE_01408 5.1e-54 fld C Flavodoxin
KOBEAFEE_01409 7.4e-52 gtcA S Teichoic acid glycosylation protein
KOBEAFEE_01410 0.0 S Bacterial membrane protein YfhO
KOBEAFEE_01411 8.9e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
KOBEAFEE_01412 1.7e-122 S Sulfite exporter TauE/SafE
KOBEAFEE_01413 2e-69 K Sugar-specific transcriptional regulator TrmB
KOBEAFEE_01414 2.4e-169 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KOBEAFEE_01415 2.3e-181 pepS E Thermophilic metalloprotease (M29)
KOBEAFEE_01416 8.7e-41 E Amino acid permease
KOBEAFEE_01417 9.2e-128 E Amino acid permease
KOBEAFEE_01418 2.4e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KOBEAFEE_01419 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KOBEAFEE_01420 5e-78 galM 5.1.3.3 G Aldose 1-epimerase
KOBEAFEE_01421 1.5e-213 malT G Transporter, major facilitator family protein
KOBEAFEE_01422 1.6e-100 malR K Transcriptional regulator, LacI family
KOBEAFEE_01423 7e-31 L Helix-turn-helix domain
KOBEAFEE_01424 3.9e-90 L PFAM Integrase catalytic region
KOBEAFEE_01425 3e-279 kup P Transport of potassium into the cell
KOBEAFEE_01427 2e-20 S Domain of unknown function (DUF3284)
KOBEAFEE_01428 6.7e-160 yfmL L DEAD DEAH box helicase
KOBEAFEE_01429 3.1e-128 mocA S Oxidoreductase
KOBEAFEE_01430 3.4e-24 S Domain of unknown function (DUF4828)
KOBEAFEE_01431 9.5e-176 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
KOBEAFEE_01432 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KOBEAFEE_01433 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
KOBEAFEE_01434 2e-118 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
KOBEAFEE_01435 2.1e-160 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KOBEAFEE_01436 1.3e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KOBEAFEE_01437 5.5e-221 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
KOBEAFEE_01438 2.2e-42 O ADP-ribosylglycohydrolase
KOBEAFEE_01439 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
KOBEAFEE_01440 3.4e-210 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
KOBEAFEE_01441 9.7e-35 K GNAT family
KOBEAFEE_01442 1.7e-40
KOBEAFEE_01444 5.5e-160 mgtE P Acts as a magnesium transporter
KOBEAFEE_01445 2.7e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
KOBEAFEE_01446 4.9e-116 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KOBEAFEE_01447 9.4e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
KOBEAFEE_01448 2.4e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KOBEAFEE_01449 3.7e-35 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KOBEAFEE_01450 1.7e-193 pbuX F xanthine permease
KOBEAFEE_01451 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KOBEAFEE_01452 6.3e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
KOBEAFEE_01453 3.2e-64 S ECF transporter, substrate-specific component
KOBEAFEE_01454 3.3e-127 mleP S Sodium Bile acid symporter family
KOBEAFEE_01455 4.4e-249 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
KOBEAFEE_01456 6.2e-72 mleR K LysR family
KOBEAFEE_01457 1.2e-57 K transcriptional
KOBEAFEE_01458 3.4e-41 K Bacterial regulatory proteins, tetR family
KOBEAFEE_01459 6.1e-60 T Belongs to the universal stress protein A family
KOBEAFEE_01460 1.2e-44 K Copper transport repressor CopY TcrY
KOBEAFEE_01461 1.6e-97 tnp2 L Transposase
KOBEAFEE_01462 1.7e-241 3.2.1.18 GH33 M Rib/alpha-like repeat
KOBEAFEE_01463 4e-98 ypuA S Protein of unknown function (DUF1002)
KOBEAFEE_01464 1.9e-59 dedA 3.1.3.1 S SNARE associated Golgi protein
KOBEAFEE_01465 6.7e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KOBEAFEE_01466 1.3e-16 yncA 2.3.1.79 S Maltose acetyltransferase
KOBEAFEE_01467 6.9e-206 yflS P Sodium:sulfate symporter transmembrane region
KOBEAFEE_01468 3.6e-199 frdC 1.3.5.4 C FAD binding domain
KOBEAFEE_01469 7.3e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KOBEAFEE_01470 5.7e-14 ybaN S Protein of unknown function (DUF454)
KOBEAFEE_01471 2.6e-57 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KOBEAFEE_01472 1.6e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KOBEAFEE_01473 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KOBEAFEE_01474 1.1e-71 ywlG S Belongs to the UPF0340 family
KOBEAFEE_01475 1.5e-175 spoVK O stage V sporulation protein K
KOBEAFEE_01476 8.7e-230 yfjM S Protein of unknown function DUF262
KOBEAFEE_01477 3.8e-73 S Domain of unknown function (DUF3841)
KOBEAFEE_01478 1.2e-54 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
KOBEAFEE_01479 1.7e-102 S Domain of unknown function (DUF4343)
KOBEAFEE_01480 0.0 L helicase activity
KOBEAFEE_01481 1.1e-210 K DNA binding
KOBEAFEE_01482 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
KOBEAFEE_01483 6.2e-221 mod 2.1.1.72, 3.1.21.5 L DNA methylase
KOBEAFEE_01484 1.6e-38 2.7.7.7 L Domain of unknown function (DUF4357)
KOBEAFEE_01485 2.4e-16
KOBEAFEE_01486 6.5e-19 S Protein of unknown function (DUF1349)
KOBEAFEE_01487 8.6e-11
KOBEAFEE_01488 1.9e-213 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KOBEAFEE_01489 9.8e-146 yegS 2.7.1.107 G Lipid kinase
KOBEAFEE_01490 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOBEAFEE_01491 1.1e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KOBEAFEE_01492 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOBEAFEE_01493 9.3e-161 camS S sex pheromone
KOBEAFEE_01494 1.3e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KOBEAFEE_01495 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KOBEAFEE_01496 5.4e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KOBEAFEE_01500 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KOBEAFEE_01501 4.7e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KOBEAFEE_01502 1.4e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KOBEAFEE_01503 1.9e-273 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KOBEAFEE_01504 1.9e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KOBEAFEE_01505 2.8e-95 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KOBEAFEE_01506 1.1e-40 yabR J RNA binding
KOBEAFEE_01507 2.6e-22 divIC D Septum formation initiator
KOBEAFEE_01508 3.6e-31 yabO J S4 domain protein
KOBEAFEE_01509 2.1e-139 yabM S Polysaccharide biosynthesis protein
KOBEAFEE_01510 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KOBEAFEE_01511 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KOBEAFEE_01512 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KOBEAFEE_01513 2.5e-86 S (CBS) domain
KOBEAFEE_01514 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KOBEAFEE_01515 1.9e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KOBEAFEE_01516 7.2e-53 perR P Belongs to the Fur family
KOBEAFEE_01517 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
KOBEAFEE_01518 1.6e-98 sbcC L Putative exonuclease SbcCD, C subunit
KOBEAFEE_01519 1.4e-116 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KOBEAFEE_01520 3.2e-48 M LysM domain protein
KOBEAFEE_01521 3e-278 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KOBEAFEE_01522 8.2e-86 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KOBEAFEE_01523 2.3e-34 ygfC K Bacterial regulatory proteins, tetR family
KOBEAFEE_01524 1.4e-110 hrtB V ABC transporter permease
KOBEAFEE_01525 1.5e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KOBEAFEE_01526 1.2e-66 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KOBEAFEE_01527 0.0 helD 3.6.4.12 L DNA helicase
KOBEAFEE_01528 2e-245 yjbQ P TrkA C-terminal domain protein
KOBEAFEE_01529 6.8e-30
KOBEAFEE_01530 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
KOBEAFEE_01531 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KOBEAFEE_01532 1.2e-124 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KOBEAFEE_01533 2.2e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOBEAFEE_01534 2e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOBEAFEE_01535 2.3e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOBEAFEE_01536 1.1e-52 rplQ J Ribosomal protein L17
KOBEAFEE_01537 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOBEAFEE_01538 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KOBEAFEE_01539 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KOBEAFEE_01540 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KOBEAFEE_01541 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KOBEAFEE_01542 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KOBEAFEE_01543 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KOBEAFEE_01544 1e-67 rplO J Binds to the 23S rRNA
KOBEAFEE_01545 2.1e-22 rpmD J Ribosomal protein L30
KOBEAFEE_01546 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KOBEAFEE_01547 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KOBEAFEE_01548 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KOBEAFEE_01549 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KOBEAFEE_01550 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KOBEAFEE_01551 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KOBEAFEE_01552 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KOBEAFEE_01553 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KOBEAFEE_01554 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KOBEAFEE_01555 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
KOBEAFEE_01556 8.1e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KOBEAFEE_01557 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KOBEAFEE_01558 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KOBEAFEE_01559 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KOBEAFEE_01560 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KOBEAFEE_01561 3.8e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KOBEAFEE_01562 1e-100 rplD J Forms part of the polypeptide exit tunnel
KOBEAFEE_01563 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KOBEAFEE_01564 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KOBEAFEE_01565 2.8e-166 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KOBEAFEE_01567 6.3e-26 K SIS domain
KOBEAFEE_01568 3.1e-18 K rpiR family
KOBEAFEE_01569 2.5e-15 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
KOBEAFEE_01570 2.3e-112 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
KOBEAFEE_01571 6.5e-21 K Acetyltransferase (GNAT) domain
KOBEAFEE_01572 2.9e-182 steT E amino acid
KOBEAFEE_01573 2.1e-77 glnP P ABC transporter permease
KOBEAFEE_01574 1.2e-85 gluC P ABC transporter permease
KOBEAFEE_01575 1.1e-99 glnH ET ABC transporter
KOBEAFEE_01576 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KOBEAFEE_01577 3.9e-08
KOBEAFEE_01578 9.4e-97
KOBEAFEE_01580 2e-52 zur P Belongs to the Fur family
KOBEAFEE_01581 4.4e-213 yfnA E Amino Acid
KOBEAFEE_01582 3.3e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KOBEAFEE_01583 0.0 L Helicase C-terminal domain protein
KOBEAFEE_01584 2.4e-80 ptp2 3.1.3.48 T Tyrosine phosphatase family
KOBEAFEE_01585 2.1e-180 yhdP S Transporter associated domain
KOBEAFEE_01586 1.7e-26
KOBEAFEE_01587 8.7e-77 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KOBEAFEE_01588 5.7e-132 bacI V MacB-like periplasmic core domain
KOBEAFEE_01589 9.6e-97 V ABC transporter
KOBEAFEE_01590 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KOBEAFEE_01591 8.9e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
KOBEAFEE_01592 1.8e-139 V MatE
KOBEAFEE_01593 3.1e-44 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KOBEAFEE_01594 1.3e-87 S Alpha beta hydrolase
KOBEAFEE_01595 2.7e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KOBEAFEE_01596 2.5e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KOBEAFEE_01597 2.2e-102 IQ Enoyl-(Acyl carrier protein) reductase
KOBEAFEE_01598 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
KOBEAFEE_01599 4.3e-54 queT S QueT transporter
KOBEAFEE_01601 7.3e-65 degV S Uncharacterised protein, DegV family COG1307
KOBEAFEE_01602 3.3e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KOBEAFEE_01603 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KOBEAFEE_01604 5.5e-34 trxA O Belongs to the thioredoxin family
KOBEAFEE_01605 3.8e-87 S Sucrose-6F-phosphate phosphohydrolase
KOBEAFEE_01606 7.1e-121 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KOBEAFEE_01607 6.3e-49 S Threonine/Serine exporter, ThrE
KOBEAFEE_01608 3.3e-82 thrE S Putative threonine/serine exporter
KOBEAFEE_01609 1.6e-97 tnp2 L Transposase
KOBEAFEE_01610 4e-27 cspC K Cold shock protein
KOBEAFEE_01611 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
KOBEAFEE_01612 2.4e-95 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KOBEAFEE_01613 6.3e-24
KOBEAFEE_01614 1.2e-58 3.6.1.27 I phosphatase
KOBEAFEE_01615 6.9e-25
KOBEAFEE_01616 5.6e-67 I alpha/beta hydrolase fold
KOBEAFEE_01617 1.3e-38 azlD S branched-chain amino acid
KOBEAFEE_01618 1.3e-102 azlC E AzlC protein
KOBEAFEE_01619 2e-17
KOBEAFEE_01620 1.5e-120 xth 3.1.11.2 L exodeoxyribonuclease III
KOBEAFEE_01621 7.8e-98 V domain protein
KOBEAFEE_01622 2.3e-16
KOBEAFEE_01626 1.9e-08 S zinc-ribbon domain
KOBEAFEE_01627 1.5e-10 S Mor transcription activator family
KOBEAFEE_01629 1.4e-26
KOBEAFEE_01630 4.5e-118 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KOBEAFEE_01631 7.6e-174 malY 4.4.1.8 E Aminotransferase, class I
KOBEAFEE_01632 3.1e-118 K AI-2E family transporter
KOBEAFEE_01633 3.9e-61 EG EamA-like transporter family
KOBEAFEE_01634 3e-76 L haloacid dehalogenase-like hydrolase
KOBEAFEE_01635 9.9e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KOBEAFEE_01636 1.7e-67 1.5.1.38 S NADPH-dependent FMN reductase
KOBEAFEE_01637 3.7e-164 C Luciferase-like monooxygenase
KOBEAFEE_01638 1.3e-41 K Transcriptional regulator, HxlR family
KOBEAFEE_01639 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KOBEAFEE_01640 3.4e-103 ydhQ K UbiC transcription regulator-associated domain protein
KOBEAFEE_01641 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KOBEAFEE_01642 2.4e-82 pncA Q isochorismatase
KOBEAFEE_01643 3.5e-63 3.1.3.73 G phosphoglycerate mutase
KOBEAFEE_01644 4.4e-217 treB G phosphotransferase system
KOBEAFEE_01645 3.1e-58 treR K UTRA
KOBEAFEE_01646 2.4e-250 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
KOBEAFEE_01647 1.4e-167 mdtG EGP Major facilitator Superfamily
KOBEAFEE_01649 3.3e-158 M Belongs to the BCCT transporter (TC 2.A.15) family
KOBEAFEE_01650 3.9e-85 M Nucleotidyl transferase
KOBEAFEE_01651 3.9e-174 licA 2.7.1.89 M Choline/ethanolamine kinase
KOBEAFEE_01652 1e-52 S Core-2/I-Branching enzyme
KOBEAFEE_01653 4.8e-57 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KOBEAFEE_01654 5.6e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KOBEAFEE_01655 4e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KOBEAFEE_01656 1.7e-126 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KOBEAFEE_01657 6.4e-178 thrC 4.2.3.1 E Threonine synthase
KOBEAFEE_01658 4.3e-83 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KOBEAFEE_01659 8.7e-26 ganB 3.2.1.89 G arabinogalactan
KOBEAFEE_01660 1.2e-60 S Psort location CytoplasmicMembrane, score
KOBEAFEE_01661 1.4e-160 XK27_08315 M Sulfatase
KOBEAFEE_01662 7.2e-96 S Bacterial membrane protein, YfhO
KOBEAFEE_01663 1.6e-16 S Bacterial membrane protein, YfhO
KOBEAFEE_01665 1.1e-31 S Bacterial membrane protein, YfhO
KOBEAFEE_01666 3.6e-14
KOBEAFEE_01667 2.8e-55 cps3I G Acyltransferase family
KOBEAFEE_01668 4.1e-149 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KOBEAFEE_01669 1.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
KOBEAFEE_01670 1.6e-156 XK27_09615 S reductase
KOBEAFEE_01671 5.4e-67 XK27_09620 S NADPH-dependent FMN reductase
KOBEAFEE_01672 7.3e-97 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KOBEAFEE_01673 9.5e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KOBEAFEE_01674 3e-310 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KOBEAFEE_01675 3e-187 S cog cog0433
KOBEAFEE_01676 1.1e-59 S SIR2-like domain
KOBEAFEE_01677 1e-274 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KOBEAFEE_01678 3.3e-132 coaA 2.7.1.33 F Pantothenic acid kinase
KOBEAFEE_01679 4.2e-40 E GDSL-like Lipase/Acylhydrolase
KOBEAFEE_01680 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KOBEAFEE_01681 5.6e-190 glnPH2 P ABC transporter permease
KOBEAFEE_01682 1.2e-213 yjeM E Amino Acid
KOBEAFEE_01683 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
KOBEAFEE_01684 8.3e-184 L Probable transposase
KOBEAFEE_01685 5.8e-137 tetA EGP Major facilitator Superfamily
KOBEAFEE_01686 1.6e-97 tnp2 L Transposase
KOBEAFEE_01688 8.1e-70 rny D Peptidase family M23
KOBEAFEE_01689 1e-188 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
KOBEAFEE_01690 4.3e-195 glf 5.4.99.9 M UDP-galactopyranose mutase
KOBEAFEE_01691 4.7e-108 S Psort location CytoplasmicMembrane, score
KOBEAFEE_01692 6.2e-95 waaB GT4 M Glycosyl transferases group 1
KOBEAFEE_01693 1.8e-111 M Core-2/I-Branching enzyme
KOBEAFEE_01694 5.1e-94 M transferase activity, transferring glycosyl groups
KOBEAFEE_01695 8.1e-67 cps3F
KOBEAFEE_01696 5.5e-89 rfbP M Bacterial sugar transferase
KOBEAFEE_01697 5.7e-127 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KOBEAFEE_01698 7.1e-112 ywqE 3.1.3.48 GM PHP domain protein
KOBEAFEE_01699 1.6e-97 tnp2 L Transposase
KOBEAFEE_01700 9.3e-82 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KOBEAFEE_01701 6.2e-71 epsB M biosynthesis protein
KOBEAFEE_01702 1.3e-25 cysE_1 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
KOBEAFEE_01703 1.9e-101
KOBEAFEE_01704 4.4e-89 2.4.1.342 GT4 M Glycosyl transferases group 1
KOBEAFEE_01705 2.5e-94 M Glycosyl transferases group 1
KOBEAFEE_01706 1.5e-06 wzy S EpsG family
KOBEAFEE_01707 5.1e-65 wcmJ M Glycosyltransferase sugar-binding region containing DXD motif
KOBEAFEE_01708 1.7e-79 M Glycosyltransferase, group 2 family protein
KOBEAFEE_01709 6.5e-116 cps2J S Polysaccharide biosynthesis protein
KOBEAFEE_01710 2.7e-27 epsH S Hexapeptide repeat of succinyl-transferase
KOBEAFEE_01711 1.7e-108 M PFAM Glycosyl transferase, group 1
KOBEAFEE_01713 4.8e-114 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
KOBEAFEE_01714 7.6e-149 prrC S AAA domain
KOBEAFEE_01715 1.2e-128 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KOBEAFEE_01716 3.3e-165 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KOBEAFEE_01717 1.2e-100 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KOBEAFEE_01718 1.6e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KOBEAFEE_01719 2.8e-75 S Glycosyltransferase like family 2
KOBEAFEE_01720 6.6e-83 S Psort location CytoplasmicMembrane, score
KOBEAFEE_01721 1.4e-99 waaB GT4 M Glycosyl transferases group 1
KOBEAFEE_01722 5.1e-62 S Glycosyltransferase like family 2
KOBEAFEE_01723 7.6e-117 cps1D M Domain of unknown function (DUF4422)
KOBEAFEE_01724 2.5e-38 S CAAX protease self-immunity
KOBEAFEE_01725 9.1e-89 yvyE 3.4.13.9 S YigZ family
KOBEAFEE_01726 7.8e-59 S Haloacid dehalogenase-like hydrolase
KOBEAFEE_01727 5.8e-154 EGP Major facilitator Superfamily
KOBEAFEE_01729 2.4e-68 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KOBEAFEE_01730 8.7e-26 adhR K helix_turn_helix, mercury resistance
KOBEAFEE_01731 2.9e-83 S NADPH-dependent FMN reductase
KOBEAFEE_01732 2e-101 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KOBEAFEE_01733 4.2e-55 S ECF transporter, substrate-specific component
KOBEAFEE_01734 2.8e-95 znuB U ABC 3 transport family
KOBEAFEE_01735 1e-98 fhuC P ABC transporter
KOBEAFEE_01736 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
KOBEAFEE_01737 1.5e-38
KOBEAFEE_01738 1.4e-53 XK27_01040 S Protein of unknown function (DUF1129)
KOBEAFEE_01739 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KOBEAFEE_01740 1.5e-23 yyzM S Bacterial protein of unknown function (DUF951)
KOBEAFEE_01741 7e-108 spo0J K Belongs to the ParB family
KOBEAFEE_01742 1.5e-117 soj D Sporulation initiation inhibitor
KOBEAFEE_01743 8.3e-82 noc K Belongs to the ParB family
KOBEAFEE_01744 4.7e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KOBEAFEE_01745 4.5e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KOBEAFEE_01746 6.4e-110 3.1.4.46 C phosphodiesterase
KOBEAFEE_01747 0.0 pacL 3.6.3.8 P P-type ATPase
KOBEAFEE_01748 1.8e-61 yvdD 3.2.2.10 S Possible lysine decarboxylase
KOBEAFEE_01749 1.4e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KOBEAFEE_01751 3.4e-62 srtA 3.4.22.70 M sortase family
KOBEAFEE_01752 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KOBEAFEE_01753 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KOBEAFEE_01754 8.2e-34
KOBEAFEE_01755 1.6e-97 tnp2 L Transposase
KOBEAFEE_01756 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KOBEAFEE_01757 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KOBEAFEE_01758 8.7e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KOBEAFEE_01759 2.8e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
KOBEAFEE_01760 3.3e-59 1.13.11.2 S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KOBEAFEE_01761 2.5e-39 ybjQ S Belongs to the UPF0145 family
KOBEAFEE_01762 3.9e-09
KOBEAFEE_01763 3.4e-94 V ABC transporter, ATP-binding protein
KOBEAFEE_01764 1.1e-41 gntR1 K Transcriptional regulator, GntR family
KOBEAFEE_01765 1.6e-97 tnp2 L Transposase
KOBEAFEE_01766 1.2e-184 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
KOBEAFEE_01767 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOBEAFEE_01768 3.8e-262 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
KOBEAFEE_01769 2.2e-107 terC P Integral membrane protein TerC family
KOBEAFEE_01770 3.6e-38 K Transcriptional regulator
KOBEAFEE_01771 8.3e-95 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KOBEAFEE_01772 1.2e-100 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KOBEAFEE_01773 6.6e-101 tcyB E ABC transporter
KOBEAFEE_01775 3.7e-13 ponA V the current gene model (or a revised gene model) may contain a frame shift
KOBEAFEE_01776 8e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KOBEAFEE_01777 7.8e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KOBEAFEE_01778 2.2e-208 mtlR K Mga helix-turn-helix domain
KOBEAFEE_01779 6.4e-176 yjcE P Sodium proton antiporter
KOBEAFEE_01780 3.8e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KOBEAFEE_01781 3.1e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
KOBEAFEE_01782 3.3e-69 dhaL 2.7.1.121 S Dak2
KOBEAFEE_01783 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
KOBEAFEE_01784 4.2e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
KOBEAFEE_01785 5e-61 K Bacterial regulatory proteins, tetR family
KOBEAFEE_01786 1.9e-208 brnQ U Component of the transport system for branched-chain amino acids
KOBEAFEE_01788 4.9e-111 endA F DNA RNA non-specific endonuclease
KOBEAFEE_01789 1.1e-75 XK27_02070 S Nitroreductase family
KOBEAFEE_01790 7.7e-192 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
KOBEAFEE_01791 4.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
KOBEAFEE_01792 3.6e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
KOBEAFEE_01793 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KOBEAFEE_01794 5.5e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
KOBEAFEE_01795 2.6e-76 azlC E branched-chain amino acid
KOBEAFEE_01796 1.6e-33 azlD S Branched-chain amino acid transport protein (AzlD)
KOBEAFEE_01797 9e-57 ohrR K helix_turn_helix multiple antibiotic resistance protein
KOBEAFEE_01798 1.2e-55 jag S R3H domain protein
KOBEAFEE_01799 6.9e-54 K Transcriptional regulator C-terminal region
KOBEAFEE_01800 5.9e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
KOBEAFEE_01801 1.4e-286 pepO 3.4.24.71 O Peptidase family M13
KOBEAFEE_01802 8.5e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
KOBEAFEE_01805 2.1e-69 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KOBEAFEE_01806 5.1e-47 hmpT S ECF-type riboflavin transporter, S component
KOBEAFEE_01807 2.8e-40 cysE 2.3.1.178 J COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOBEAFEE_01809 3.2e-34 tetR K transcriptional regulator
KOBEAFEE_01810 3.1e-20
KOBEAFEE_01812 7e-70 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KOBEAFEE_01813 1.1e-24 ytbE C Aldo keto reductase
KOBEAFEE_01814 2.1e-18 ytcD K HxlR-like helix-turn-helix
KOBEAFEE_01815 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
KOBEAFEE_01816 2e-67 ybbL S ABC transporter
KOBEAFEE_01817 1.4e-162 oxlT P Major Facilitator Superfamily
KOBEAFEE_01818 1.8e-52 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KOBEAFEE_01819 6.1e-21 L An automated process has identified a potential problem with this gene model
KOBEAFEE_01820 7e-181 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
KOBEAFEE_01821 4.4e-29 tetR K Transcriptional regulator C-terminal region
KOBEAFEE_01822 4.2e-151 yfeX P Peroxidase
KOBEAFEE_01823 1.7e-17 S Protein of unknown function (DUF3021)
KOBEAFEE_01824 4e-40 K LytTr DNA-binding domain
KOBEAFEE_01825 3.1e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KOBEAFEE_01826 1.1e-208 mmuP E amino acid
KOBEAFEE_01827 1.2e-15 psiE S Phosphate-starvation-inducible E
KOBEAFEE_01828 9.7e-156 oppF P Belongs to the ABC transporter superfamily
KOBEAFEE_01829 1.3e-180 oppD P Belongs to the ABC transporter superfamily
KOBEAFEE_01830 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOBEAFEE_01831 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOBEAFEE_01832 3.1e-202 oppA E ABC transporter, substratebinding protein
KOBEAFEE_01833 2.7e-218 yifK E Amino acid permease
KOBEAFEE_01834 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KOBEAFEE_01835 3.9e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
KOBEAFEE_01836 5e-66 pgm3 G phosphoglycerate mutase family
KOBEAFEE_01837 1.3e-252 ctpA 3.6.3.54 P P-type ATPase
KOBEAFEE_01838 2.5e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KOBEAFEE_01839 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KOBEAFEE_01840 1.4e-148 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KOBEAFEE_01841 1.2e-21 K transcriptional regulator
KOBEAFEE_01842 1.9e-76 hchA S intracellular protease amidase
KOBEAFEE_01843 5.1e-137 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
KOBEAFEE_01844 4.3e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KOBEAFEE_01845 9.5e-140 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KOBEAFEE_01846 1.6e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
KOBEAFEE_01847 1e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
KOBEAFEE_01848 6e-25 1.3.5.4 C FMN_bind
KOBEAFEE_01849 7.6e-162 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
KOBEAFEE_01850 5.9e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
KOBEAFEE_01851 5.2e-76 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KOBEAFEE_01852 1.2e-128 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
KOBEAFEE_01853 3.8e-93 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KOBEAFEE_01854 5.6e-82 S Belongs to the UPF0246 family
KOBEAFEE_01855 7.9e-12 S CAAX protease self-immunity
KOBEAFEE_01856 4.6e-59 ykhA 3.1.2.20 I Thioesterase superfamily
KOBEAFEE_01857 3.9e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KOBEAFEE_01859 2.8e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KOBEAFEE_01860 1e-90 L PFAM Integrase catalytic region
KOBEAFEE_01861 7e-31 L Helix-turn-helix domain
KOBEAFEE_01862 1.1e-64 C FMN binding
KOBEAFEE_01863 6.7e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KOBEAFEE_01864 3.9e-54 rplI J Binds to the 23S rRNA
KOBEAFEE_01865 2.6e-262 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KOBEAFEE_01866 1.4e-06
KOBEAFEE_01872 5.1e-08
KOBEAFEE_01881 4.5e-29 yqkB S Belongs to the HesB IscA family
KOBEAFEE_01882 6e-66 yxkH G Polysaccharide deacetylase
KOBEAFEE_01883 4.1e-07
KOBEAFEE_01884 1.6e-97 tnp2 L Transposase
KOBEAFEE_01885 1.7e-53 K LysR substrate binding domain
KOBEAFEE_01886 1.5e-122 MA20_14895 S Conserved hypothetical protein 698
KOBEAFEE_01887 1.1e-199 nupG F Nucleoside
KOBEAFEE_01888 5.3e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KOBEAFEE_01889 3.7e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KOBEAFEE_01890 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KOBEAFEE_01891 9.4e-109 L Initiator Replication protein
KOBEAFEE_01892 3.9e-38 S Replication initiator protein A (RepA) N-terminus
KOBEAFEE_01893 6.3e-130 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KOBEAFEE_01894 2.8e-43 bglP5 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Pts system
KOBEAFEE_01895 1.6e-25 G Pts system
KOBEAFEE_01896 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
KOBEAFEE_01898 4.9e-36
KOBEAFEE_01899 0.0 pepN 3.4.11.2 E aminopeptidase
KOBEAFEE_01902 7.9e-125 yvgN C Aldo keto reductase
KOBEAFEE_01903 9e-88 iolR K DeoR C terminal sensor domain
KOBEAFEE_01904 1.9e-227 iolA 1.2.1.18, 1.2.1.27 C Belongs to the aldehyde dehydrogenase family
KOBEAFEE_01905 1.7e-103 iolB 5.3.1.30 G KduI/IolB family
KOBEAFEE_01906 3.3e-135 iolC 2.7.1.92 G Belongs to the carbohydrate kinase PfkB family
KOBEAFEE_01907 3.9e-281 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KOBEAFEE_01908 4.5e-151 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KOBEAFEE_01909 1.5e-146 iolG2 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
KOBEAFEE_01910 1.3e-130 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KOBEAFEE_01911 2.8e-248 yidK S Sodium:solute symporter family
KOBEAFEE_01912 5.8e-25 G PTS system, Lactose/Cellobiose specific IIB subunit
KOBEAFEE_01913 9.6e-145 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KOBEAFEE_01914 1.9e-36 S Tautomerase enzyme
KOBEAFEE_01915 9.6e-21 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
KOBEAFEE_01916 8.2e-122 yvgN C Aldo keto reductase
KOBEAFEE_01917 1.1e-69 K DeoR C terminal sensor domain
KOBEAFEE_01918 1.1e-46 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KOBEAFEE_01919 2.6e-41 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
KOBEAFEE_01920 4.2e-217 pts36C G PTS system sugar-specific permease component
KOBEAFEE_01922 5.1e-104 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
KOBEAFEE_01924 3.8e-33 S COG NOG19168 non supervised orthologous group
KOBEAFEE_01925 1.7e-190 XK27_11280 S Psort location CytoplasmicMembrane, score
KOBEAFEE_01927 4.1e-68 L Belongs to the 'phage' integrase family
KOBEAFEE_01928 4.3e-18 3.1.21.3 V Type I restriction modification DNA specificity domain
KOBEAFEE_01930 2.3e-52 hsdM 2.1.1.72 L N-6 DNA Methylase
KOBEAFEE_01932 5.4e-58 sthIM 2.1.1.72 L DNA methylase
KOBEAFEE_01933 5.2e-94 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
KOBEAFEE_01934 7.2e-235 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
KOBEAFEE_01935 5.1e-56 2.1.1.72 L Type III restriction/modification enzyme methylation subunit
KOBEAFEE_01936 4.1e-128 sthIM 2.1.1.72 L DNA methylase
KOBEAFEE_01937 3.1e-260 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
KOBEAFEE_01938 4.6e-16
KOBEAFEE_01939 3.4e-25
KOBEAFEE_01940 1.5e-48 L HNH endonuclease
KOBEAFEE_01943 4.7e-153 potE2 E amino acid
KOBEAFEE_01944 1.3e-15 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KOBEAFEE_01945 2.1e-116 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KOBEAFEE_01946 1.6e-56 racA K Domain of unknown function (DUF1836)
KOBEAFEE_01947 3.1e-81 yitS S EDD domain protein, DegV family
KOBEAFEE_01948 2.9e-36 S Enterocin A Immunity
KOBEAFEE_01949 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KOBEAFEE_01950 0.0 O Belongs to the peptidase S8 family
KOBEAFEE_01951 1.9e-18 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
KOBEAFEE_01952 3e-69 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
KOBEAFEE_01953 3.3e-115 K Transcriptional regulator
KOBEAFEE_01954 6.5e-293 M Exporter of polyketide antibiotics
KOBEAFEE_01955 5.7e-169 yjjC V ABC transporter
KOBEAFEE_01956 2.1e-26 S protein encoded in hypervariable junctions of pilus gene clusters
KOBEAFEE_01957 9e-102 qmcA O prohibitin homologues
KOBEAFEE_01958 1.8e-183 L Probable transposase
KOBEAFEE_01959 1.4e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
KOBEAFEE_01960 1.1e-14 tnp L Transposase IS66 family
KOBEAFEE_01961 5.4e-85 dps P Ferritin-like domain
KOBEAFEE_01962 3e-125 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
KOBEAFEE_01963 7e-31 P Heavy-metal-associated domain
KOBEAFEE_01964 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
KOBEAFEE_01966 1.7e-32 L PFAM Integrase catalytic region
KOBEAFEE_01967 1.3e-181 L Probable transposase
KOBEAFEE_01968 2.6e-38 L Integrase core domain
KOBEAFEE_01969 2.6e-129 EGP Major Facilitator Superfamily
KOBEAFEE_01970 1.4e-98 EGP Major Facilitator Superfamily
KOBEAFEE_01971 6.3e-72 K Transcriptional regulator, LysR family
KOBEAFEE_01972 6.2e-138 G Xylose isomerase-like TIM barrel
KOBEAFEE_01973 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
KOBEAFEE_01974 2.3e-216 1.3.5.4 C FAD binding domain
KOBEAFEE_01975 8.4e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KOBEAFEE_01976 2.5e-69 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KOBEAFEE_01977 1.1e-142 xerS L Phage integrase family
KOBEAFEE_01978 1.3e-08 S Domain of unknown function (DUF4417)
KOBEAFEE_01982 8.9e-104 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KOBEAFEE_01983 1.6e-71 ptp3 3.1.3.48 T Tyrosine phosphatase family
KOBEAFEE_01984 7.5e-77 desR K helix_turn_helix, Lux Regulon
KOBEAFEE_01985 1.2e-56 desK 2.7.13.3 T Histidine kinase
KOBEAFEE_01986 1.9e-53 yvfS V ABC-2 type transporter
KOBEAFEE_01987 3.6e-80 yvfR V ABC transporter
KOBEAFEE_01988 4.6e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KOBEAFEE_01989 9.5e-78 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KOBEAFEE_01990 4.6e-30
KOBEAFEE_01991 1.3e-61 sip L Belongs to the 'phage' integrase family
KOBEAFEE_01992 5e-07
KOBEAFEE_01995 1.9e-29 M CHAP domain
KOBEAFEE_01997 1.5e-192 U type IV secretory pathway VirB4
KOBEAFEE_01998 3.5e-27
KOBEAFEE_02000 2.9e-75
KOBEAFEE_02001 5.8e-220 U TraM recognition site of TraD and TraG
KOBEAFEE_02005 1.3e-148 clpB O Belongs to the ClpA ClpB family
KOBEAFEE_02008 1.9e-165 topA2 5.99.1.2 G Topoisomerase IA
KOBEAFEE_02009 6.8e-42 L Protein of unknown function (DUF3991)
KOBEAFEE_02010 1.7e-68
KOBEAFEE_02012 1.4e-40 V Type I restriction modification DNA specificity domain
KOBEAFEE_02013 4.2e-212 V N-6 DNA Methylase
KOBEAFEE_02014 3.5e-22 S PIN domain
KOBEAFEE_02015 2.6e-11 D Antitoxin component of a toxin-antitoxin (TA) module
KOBEAFEE_02016 8.4e-90 pac DM Glucan-binding protein C
KOBEAFEE_02018 8.9e-12 sdrF M domain protein
KOBEAFEE_02019 9.9e-73 L Belongs to the 'phage' integrase family
KOBEAFEE_02020 1.6e-97 tnp2 L Transposase
KOBEAFEE_02021 4.4e-58 Z012_06740 S Fic/DOC family
KOBEAFEE_02024 1.6e-28
KOBEAFEE_02025 1.2e-61 gepA K Protein of unknown function (DUF4065)
KOBEAFEE_02026 4.4e-08
KOBEAFEE_02027 1.7e-25 D nuclear chromosome segregation
KOBEAFEE_02029 7.4e-79 S Fic/DOC family
KOBEAFEE_02033 2.1e-60 ruvB 3.6.4.12 L four-way junction helicase activity
KOBEAFEE_02037 5.4e-11 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
KOBEAFEE_02038 4.4e-20
KOBEAFEE_02046 1.8e-06
KOBEAFEE_02051 7.6e-21 S Replication initiator protein A (RepA) N-terminus
KOBEAFEE_02054 8.2e-10 S Arc-like DNA binding domain
KOBEAFEE_02063 6.4e-11 S sequence-specific DNA binding
KOBEAFEE_02064 1.4e-88 S Fic/DOC family
KOBEAFEE_02065 1.6e-97 tnp2 L Transposase
KOBEAFEE_02066 1.1e-69 S Protein of unknown function (DUF4065)
KOBEAFEE_02067 2.6e-57 S Region found in RelA / SpoT proteins
KOBEAFEE_02068 3.7e-38
KOBEAFEE_02070 1.1e-15
KOBEAFEE_02071 3.6e-112 rssA S Phospholipase, patatin family
KOBEAFEE_02072 2.6e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KOBEAFEE_02073 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
KOBEAFEE_02074 3.3e-45 S VIT family
KOBEAFEE_02075 1.2e-239 sufB O assembly protein SufB
KOBEAFEE_02076 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
KOBEAFEE_02077 2.2e-147 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KOBEAFEE_02078 4.6e-145 sufD O FeS assembly protein SufD
KOBEAFEE_02079 6.2e-116 sufC O FeS assembly ATPase SufC
KOBEAFEE_02080 1.2e-225 E ABC transporter, substratebinding protein
KOBEAFEE_02081 3.3e-27 K Helix-turn-helix XRE-family like proteins
KOBEAFEE_02082 3.3e-136 pfoS S Phosphotransferase system, EIIC
KOBEAFEE_02083 5.5e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
KOBEAFEE_02084 3.6e-13 dnaG M by MetaGeneAnnotator
KOBEAFEE_02086 6.9e-59 dnaG S EVIDENCE BY HOMOLOGY BIO14.03 Phage related functions and prophages
KOBEAFEE_02087 1.2e-51 M Phage tail tape measure protein TP901
KOBEAFEE_02092 1.2e-32 S Phage minor capsid protein 2
KOBEAFEE_02093 2.1e-99 fabK 1.3.1.9 S Nitronate monooxygenase
KOBEAFEE_02094 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KOBEAFEE_02096 6e-38 tonB M YSIRK type signal peptide
KOBEAFEE_02097 2.8e-266 fbp 3.1.3.11 G phosphatase activity
KOBEAFEE_02098 1.9e-70 xerD L Phage integrase, N-terminal SAM-like domain
KOBEAFEE_02100 8.8e-07 blpT
KOBEAFEE_02101 2.3e-14
KOBEAFEE_02103 7.8e-187 mtnE 2.6.1.83 E Aminotransferase
KOBEAFEE_02104 1e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
KOBEAFEE_02105 3.4e-67 S Protein of unknown function (DUF1440)
KOBEAFEE_02106 7.7e-41 S Iron-sulfur cluster assembly protein
KOBEAFEE_02107 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KOBEAFEE_02108 1.9e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KOBEAFEE_02109 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KOBEAFEE_02110 3e-154 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KOBEAFEE_02111 4.7e-65 G Xylose isomerase domain protein TIM barrel
KOBEAFEE_02112 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
KOBEAFEE_02113 1.7e-90 nanK GK ROK family
KOBEAFEE_02114 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
KOBEAFEE_02115 3.3e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KOBEAFEE_02116 4.3e-75 K Helix-turn-helix domain, rpiR family
KOBEAFEE_02117 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
KOBEAFEE_02118 1e-145 yjeM E Amino Acid
KOBEAFEE_02119 1.5e-159 L transposase, IS605 OrfB family
KOBEAFEE_02120 3.3e-58 tlpA2 L Transposase IS200 like
KOBEAFEE_02121 1.5e-46 yjeM E Amino Acid
KOBEAFEE_02123 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KOBEAFEE_02124 2.5e-235 tetP J elongation factor G
KOBEAFEE_02126 2.5e-11 tcdC
KOBEAFEE_02128 2.6e-52 L Protein involved in initiation of plasmid replication
KOBEAFEE_02131 1.5e-54 L Phage integrase, N-terminal SAM-like domain
KOBEAFEE_02132 2.7e-28 L Single-strand binding protein family
KOBEAFEE_02133 4.1e-86 L Replication initiation factor
KOBEAFEE_02134 7.5e-26 yqfZ 3.2.1.17 M hydrolase, family 25
KOBEAFEE_02135 4.5e-28
KOBEAFEE_02136 1.6e-56 S MTH538 TIR-like domain (DUF1863)
KOBEAFEE_02137 1.9e-40
KOBEAFEE_02138 7.4e-53 L SinI restriction endonuclease
KOBEAFEE_02139 8.6e-185 sinIM 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KOBEAFEE_02140 1.1e-48 L Resolvase, N terminal domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)