ORF_ID e_value Gene_name EC_number CAZy COGs Description
NECCCLDA_00001 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NECCCLDA_00002 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NECCCLDA_00003 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NECCCLDA_00004 2.7e-249 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NECCCLDA_00005 3.4e-39 S COG NOG14552 non supervised orthologous group
NECCCLDA_00010 2e-08
NECCCLDA_00019 2e-08
NECCCLDA_00026 1.3e-09
NECCCLDA_00027 7.8e-08
NECCCLDA_00036 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NECCCLDA_00037 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NECCCLDA_00038 8.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NECCCLDA_00039 7.1e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NECCCLDA_00040 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NECCCLDA_00041 1.9e-75 tspO T membrane
NECCCLDA_00042 4.4e-205 cotI S Spore coat protein
NECCCLDA_00043 2.2e-215 cotSA M Glycosyl transferases group 1
NECCCLDA_00044 9.7e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
NECCCLDA_00046 8.2e-232 ytcC M Glycosyltransferase Family 4
NECCCLDA_00047 2.6e-177 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NECCCLDA_00048 1.9e-242 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NECCCLDA_00049 2.5e-152 galU 2.7.7.9 M Nucleotidyl transferase
NECCCLDA_00050 2.6e-132 dksA T COG1734 DnaK suppressor protein
NECCCLDA_00051 2.1e-271 menF 5.4.4.2 HQ Isochorismate synthase
NECCCLDA_00052 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NECCCLDA_00053 1.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NECCCLDA_00054 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NECCCLDA_00055 1.7e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NECCCLDA_00056 2.7e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NECCCLDA_00057 1.3e-168 troA P Belongs to the bacterial solute-binding protein 9 family
NECCCLDA_00058 1e-136 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NECCCLDA_00059 4.8e-230 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NECCCLDA_00060 4.4e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NECCCLDA_00061 1.1e-24 S Domain of Unknown Function (DUF1540)
NECCCLDA_00062 4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NECCCLDA_00063 1.8e-248 cydA 1.10.3.14 C oxidase, subunit
NECCCLDA_00064 3.6e-41 rpmE2 J Ribosomal protein L31
NECCCLDA_00065 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NECCCLDA_00066 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NECCCLDA_00067 1.1e-72 ytkA S YtkA-like
NECCCLDA_00069 2.1e-76 dps P Belongs to the Dps family
NECCCLDA_00070 7e-63 ytkC S Bacteriophage holin family
NECCCLDA_00071 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NECCCLDA_00072 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NECCCLDA_00073 1.4e-144 ytlC P ABC transporter
NECCCLDA_00074 1.8e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NECCCLDA_00075 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NECCCLDA_00076 1.2e-38 ytmB S Protein of unknown function (DUF2584)
NECCCLDA_00077 1.1e-308 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NECCCLDA_00078 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NECCCLDA_00079 0.0 asnB 6.3.5.4 E Asparagine synthase
NECCCLDA_00080 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NECCCLDA_00081 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NECCCLDA_00082 2.8e-148 ytpA 3.1.1.5 I Alpha beta hydrolase
NECCCLDA_00083 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NECCCLDA_00084 1.2e-103 ytqB J Putative rRNA methylase
NECCCLDA_00085 8.1e-190 yhcC S Fe-S oxidoreductase
NECCCLDA_00086 6.7e-41 ytzC S Protein of unknown function (DUF2524)
NECCCLDA_00088 5.1e-66 ytrA K GntR family transcriptional regulator
NECCCLDA_00089 4.2e-161 ytrB P abc transporter atp-binding protein
NECCCLDA_00090 2e-164 P ABC-2 family transporter protein
NECCCLDA_00091 6.3e-150
NECCCLDA_00092 9.1e-127 ytrE V ABC transporter, ATP-binding protein
NECCCLDA_00093 2.1e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NECCCLDA_00094 5.7e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECCCLDA_00095 3.4e-183 T PhoQ Sensor
NECCCLDA_00096 1.1e-138 bceA V ABC transporter, ATP-binding protein
NECCCLDA_00097 0.0 bceB V ABC transporter (permease)
NECCCLDA_00098 1.1e-42 yttA 2.7.13.3 S Pfam Transposase IS66
NECCCLDA_00099 6e-211 yttB EGP Major facilitator Superfamily
NECCCLDA_00100 1.1e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NECCCLDA_00101 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NECCCLDA_00102 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NECCCLDA_00103 8.1e-51 ytwF P Sulfurtransferase
NECCCLDA_00104 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NECCCLDA_00105 4.4e-144 amyC P ABC transporter (permease)
NECCCLDA_00106 6.2e-168 amyD P ABC transporter
NECCCLDA_00107 6.8e-245 msmE G Bacterial extracellular solute-binding protein
NECCCLDA_00108 2.5e-189 msmR K Transcriptional regulator
NECCCLDA_00109 9.2e-172 ytaP S Acetyl xylan esterase (AXE1)
NECCCLDA_00110 3.8e-139 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NECCCLDA_00111 2.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NECCCLDA_00112 2.5e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NECCCLDA_00113 1.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NECCCLDA_00114 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NECCCLDA_00115 4.5e-219 bioI 1.14.14.46 C Cytochrome P450
NECCCLDA_00116 1.2e-135 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NECCCLDA_00117 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
NECCCLDA_00118 6.9e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NECCCLDA_00119 0.0 ytdP K Transcriptional regulator
NECCCLDA_00120 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NECCCLDA_00121 1.5e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NECCCLDA_00122 3.9e-72 yteS G transport
NECCCLDA_00123 5e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NECCCLDA_00124 2.6e-115 yteU S Integral membrane protein
NECCCLDA_00125 3.1e-26 yteV S Sporulation protein Cse60
NECCCLDA_00126 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NECCCLDA_00127 1.4e-231 ytfP S HI0933-like protein
NECCCLDA_00128 4.2e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NECCCLDA_00129 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NECCCLDA_00130 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NECCCLDA_00131 6.2e-131 ythP V ABC transporter
NECCCLDA_00132 6e-200 ythQ U Bacterial ABC transporter protein EcsB
NECCCLDA_00133 7.2e-226 pbuO S permease
NECCCLDA_00134 2.3e-270 pepV 3.5.1.18 E Dipeptidase
NECCCLDA_00135 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NECCCLDA_00136 8.9e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NECCCLDA_00137 1.3e-165 ytlQ
NECCCLDA_00138 2.5e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NECCCLDA_00139 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NECCCLDA_00140 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
NECCCLDA_00141 2e-45 ytzH S YtzH-like protein
NECCCLDA_00142 2.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NECCCLDA_00143 1.6e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NECCCLDA_00144 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NECCCLDA_00145 2.2e-51 ytzB S small secreted protein
NECCCLDA_00146 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NECCCLDA_00147 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NECCCLDA_00148 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NECCCLDA_00149 9.8e-149 ytpQ S Belongs to the UPF0354 family
NECCCLDA_00150 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NECCCLDA_00151 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NECCCLDA_00152 4.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NECCCLDA_00153 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NECCCLDA_00154 6.6e-17 ytxH S COG4980 Gas vesicle protein
NECCCLDA_00155 2.8e-54 ytxJ O Protein of unknown function (DUF2847)
NECCCLDA_00156 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NECCCLDA_00157 1.7e-182 ccpA K catabolite control protein A
NECCCLDA_00158 6e-146 motA N flagellar motor
NECCCLDA_00159 6.8e-125 motS N Flagellar motor protein
NECCCLDA_00160 6.1e-224 acuC BQ histone deacetylase
NECCCLDA_00161 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
NECCCLDA_00162 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NECCCLDA_00163 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NECCCLDA_00164 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NECCCLDA_00166 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NECCCLDA_00167 2.4e-311 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NECCCLDA_00168 2.2e-87 ytsP 1.8.4.14 T GAF domain-containing protein
NECCCLDA_00169 1e-108 yttP K Transcriptional regulator
NECCCLDA_00170 3.5e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NECCCLDA_00171 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NECCCLDA_00172 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
NECCCLDA_00173 1e-207 iscS2 2.8.1.7 E Cysteine desulfurase
NECCCLDA_00174 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NECCCLDA_00175 2e-29 sspB S spore protein
NECCCLDA_00176 5e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NECCCLDA_00177 0.0 ytcJ S amidohydrolase
NECCCLDA_00178 8.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NECCCLDA_00179 2.3e-179 sppA OU signal peptide peptidase SppA
NECCCLDA_00180 8.5e-87 yteJ S RDD family
NECCCLDA_00181 8.1e-115 ytfI S Protein of unknown function (DUF2953)
NECCCLDA_00182 8.7e-70 ytfJ S Sporulation protein YtfJ
NECCCLDA_00183 5.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NECCCLDA_00184 7e-165 ytxK 2.1.1.72 L DNA methylase
NECCCLDA_00185 1.8e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NECCCLDA_00186 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NECCCLDA_00187 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NECCCLDA_00188 9.9e-266 argH 4.3.2.1 E argininosuccinate lyase
NECCCLDA_00190 3.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECCCLDA_00191 1.7e-130 ytkL S Belongs to the UPF0173 family
NECCCLDA_00192 8e-241 ytoI K transcriptional regulator containing CBS domains
NECCCLDA_00193 2.4e-47 ytpI S YtpI-like protein
NECCCLDA_00194 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NECCCLDA_00195 9.2e-29
NECCCLDA_00196 8.2e-69 ytrI
NECCCLDA_00197 3.2e-56 ytrH S Sporulation protein YtrH
NECCCLDA_00198 0.0 dnaE 2.7.7.7 L DNA polymerase
NECCCLDA_00199 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NECCCLDA_00200 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NECCCLDA_00201 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NECCCLDA_00202 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NECCCLDA_00203 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NECCCLDA_00204 1.6e-61 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NECCCLDA_00205 4.4e-192 ytvI S sporulation integral membrane protein YtvI
NECCCLDA_00206 4.7e-71 yeaL S membrane
NECCCLDA_00207 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NECCCLDA_00208 4.1e-242 icd 1.1.1.42 C isocitrate
NECCCLDA_00209 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NECCCLDA_00210 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECCCLDA_00211 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NECCCLDA_00212 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NECCCLDA_00213 3.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NECCCLDA_00214 1.1e-107 ytaF P Probably functions as a manganese efflux pump
NECCCLDA_00215 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NECCCLDA_00216 2e-160 ytbE S reductase
NECCCLDA_00217 7.1e-204 ytbD EGP Major facilitator Superfamily
NECCCLDA_00218 4.9e-66 ytcD K Transcriptional regulator
NECCCLDA_00219 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NECCCLDA_00220 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NECCCLDA_00221 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NECCCLDA_00222 2.2e-265 dnaB L Membrane attachment protein
NECCCLDA_00223 2.5e-172 dnaI L Primosomal protein DnaI
NECCCLDA_00224 6e-109 ytxB S SNARE associated Golgi protein
NECCCLDA_00225 1.4e-158 ytxC S YtxC-like family
NECCCLDA_00227 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NECCCLDA_00228 2.8e-148 ysaA S HAD-hyrolase-like
NECCCLDA_00229 0.0 lytS 2.7.13.3 T Histidine kinase
NECCCLDA_00230 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
NECCCLDA_00231 3.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NECCCLDA_00232 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NECCCLDA_00234 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NECCCLDA_00235 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NECCCLDA_00236 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NECCCLDA_00237 7.5e-45 ysdA S Membrane
NECCCLDA_00238 3.5e-67 ysdB S Sigma-w pathway protein YsdB
NECCCLDA_00239 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
NECCCLDA_00240 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NECCCLDA_00241 1.6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NECCCLDA_00242 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NECCCLDA_00243 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NECCCLDA_00244 3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NECCCLDA_00245 7.5e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NECCCLDA_00246 5.3e-253 araN G carbohydrate transport
NECCCLDA_00247 4.2e-167 araP G carbohydrate transport
NECCCLDA_00248 3.4e-144 araQ G transport system permease
NECCCLDA_00249 3.9e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NECCCLDA_00250 0.0 cstA T Carbon starvation protein
NECCCLDA_00251 4.5e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
NECCCLDA_00252 2.3e-256 glcF C Glycolate oxidase
NECCCLDA_00253 5.7e-261 glcD 1.1.3.15 C Glycolate oxidase subunit
NECCCLDA_00254 8.6e-204 ysfB KT regulator
NECCCLDA_00255 5.8e-32 sspI S Belongs to the SspI family
NECCCLDA_00256 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NECCCLDA_00257 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NECCCLDA_00258 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NECCCLDA_00259 1.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NECCCLDA_00260 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NECCCLDA_00261 1.3e-85 cvpA S membrane protein, required for colicin V production
NECCCLDA_00262 0.0 polX L COG1796 DNA polymerase IV (family X)
NECCCLDA_00263 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NECCCLDA_00264 7.3e-68 yshE S membrane
NECCCLDA_00265 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NECCCLDA_00266 4e-99 fadR K Transcriptional regulator
NECCCLDA_00267 2.7e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NECCCLDA_00268 1.3e-134 etfB C Electron transfer flavoprotein
NECCCLDA_00269 1.3e-176 etfA C Electron transfer flavoprotein
NECCCLDA_00271 2.6e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NECCCLDA_00272 2e-52 trxA O Belongs to the thioredoxin family
NECCCLDA_00273 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NECCCLDA_00274 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NECCCLDA_00275 1.2e-79 yslB S Protein of unknown function (DUF2507)
NECCCLDA_00276 2.4e-107 sdhC C succinate dehydrogenase
NECCCLDA_00277 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NECCCLDA_00278 1.7e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NECCCLDA_00279 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NECCCLDA_00280 3.3e-30 gerE K Transcriptional regulator
NECCCLDA_00281 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NECCCLDA_00282 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NECCCLDA_00283 5e-196 gerM S COG5401 Spore germination protein
NECCCLDA_00284 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NECCCLDA_00285 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NECCCLDA_00286 5.3e-92 ysnB S Phosphoesterase
NECCCLDA_00288 3.8e-132 ysnF S protein conserved in bacteria
NECCCLDA_00289 9.6e-77 ysnE K acetyltransferase
NECCCLDA_00291 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NECCCLDA_00292 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
NECCCLDA_00293 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NECCCLDA_00294 9.3e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NECCCLDA_00295 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NECCCLDA_00296 8.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NECCCLDA_00297 2.6e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NECCCLDA_00298 1.9e-186 ysoA H Tetratricopeptide repeat
NECCCLDA_00299 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NECCCLDA_00300 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NECCCLDA_00301 6e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NECCCLDA_00302 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NECCCLDA_00303 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NECCCLDA_00304 5.4e-89 ysxD
NECCCLDA_00305 5.9e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NECCCLDA_00306 3e-145 hemX O cytochrome C
NECCCLDA_00307 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NECCCLDA_00308 2.7e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NECCCLDA_00309 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
NECCCLDA_00310 4.7e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NECCCLDA_00311 4.3e-202 spoVID M stage VI sporulation protein D
NECCCLDA_00312 2.9e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NECCCLDA_00313 1.6e-25
NECCCLDA_00314 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NECCCLDA_00315 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NECCCLDA_00316 5.6e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NECCCLDA_00317 3.8e-166 spoIIB S Sporulation related domain
NECCCLDA_00318 2.8e-102 maf D septum formation protein Maf
NECCCLDA_00319 1.5e-124 radC E Belongs to the UPF0758 family
NECCCLDA_00320 1.8e-184 mreB D Rod shape-determining protein MreB
NECCCLDA_00321 2.8e-157 mreC M Involved in formation and maintenance of cell shape
NECCCLDA_00322 1.4e-84 mreD M shape-determining protein
NECCCLDA_00323 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NECCCLDA_00324 2.5e-144 minD D Belongs to the ParA family
NECCCLDA_00325 8.5e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NECCCLDA_00326 9.2e-161 spoIVFB S Stage IV sporulation protein
NECCCLDA_00327 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NECCCLDA_00328 4.1e-56 ysxB J ribosomal protein
NECCCLDA_00329 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NECCCLDA_00330 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NECCCLDA_00331 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NECCCLDA_00332 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NECCCLDA_00333 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
NECCCLDA_00334 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
NECCCLDA_00335 5.9e-227 nifS 2.8.1.7 E Cysteine desulfurase
NECCCLDA_00336 7e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NECCCLDA_00337 8.1e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NECCCLDA_00338 4.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NECCCLDA_00339 8.3e-157 safA M spore coat assembly protein SafA
NECCCLDA_00340 1.3e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NECCCLDA_00341 3.6e-126 yebC K transcriptional regulatory protein
NECCCLDA_00342 5.3e-262 alsT E Sodium alanine symporter
NECCCLDA_00344 2.3e-51 S Family of unknown function (DUF5412)
NECCCLDA_00346 6.5e-119 yrzF T serine threonine protein kinase
NECCCLDA_00347 1.7e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NECCCLDA_00348 4.5e-252 csbX EGP Major facilitator Superfamily
NECCCLDA_00349 4.8e-93 bofC S BofC C-terminal domain
NECCCLDA_00350 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NECCCLDA_00351 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NECCCLDA_00352 2.6e-18 yrzS S Protein of unknown function (DUF2905)
NECCCLDA_00353 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NECCCLDA_00354 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NECCCLDA_00355 1.1e-38 yajC U Preprotein translocase subunit YajC
NECCCLDA_00356 2.2e-73 yrzE S Protein of unknown function (DUF3792)
NECCCLDA_00357 1.3e-111 yrbG S membrane
NECCCLDA_00358 1.2e-267 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NECCCLDA_00359 1.6e-48 yrzD S Post-transcriptional regulator
NECCCLDA_00360 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NECCCLDA_00361 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NECCCLDA_00362 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NECCCLDA_00363 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NECCCLDA_00364 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NECCCLDA_00365 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NECCCLDA_00366 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NECCCLDA_00367 1.1e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
NECCCLDA_00369 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NECCCLDA_00370 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NECCCLDA_00371 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NECCCLDA_00372 1.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NECCCLDA_00373 1.2e-70 cymR K Transcriptional regulator
NECCCLDA_00374 2.2e-210 iscS 2.8.1.7 E Cysteine desulfurase
NECCCLDA_00375 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NECCCLDA_00376 1.4e-15 S COG0457 FOG TPR repeat
NECCCLDA_00377 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NECCCLDA_00378 1.7e-81 yrrD S protein conserved in bacteria
NECCCLDA_00379 9.8e-31 yrzR
NECCCLDA_00380 8e-08 S Protein of unknown function (DUF3918)
NECCCLDA_00381 2.2e-106 glnP P ABC transporter
NECCCLDA_00382 5.2e-108 gluC P ABC transporter
NECCCLDA_00383 1.3e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
NECCCLDA_00384 2.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NECCCLDA_00385 2.7e-170 yrrI S AI-2E family transporter
NECCCLDA_00386 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NECCCLDA_00387 1.7e-41 yrzL S Belongs to the UPF0297 family
NECCCLDA_00388 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NECCCLDA_00389 1.2e-45 yrzB S Belongs to the UPF0473 family
NECCCLDA_00390 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NECCCLDA_00391 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
NECCCLDA_00392 1.9e-172 yegQ O Peptidase U32
NECCCLDA_00393 2.7e-246 yegQ O COG0826 Collagenase and related proteases
NECCCLDA_00394 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NECCCLDA_00395 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NECCCLDA_00396 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NECCCLDA_00397 4.5e-57 yrrS S Protein of unknown function (DUF1510)
NECCCLDA_00398 1e-25 yrzA S Protein of unknown function (DUF2536)
NECCCLDA_00399 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NECCCLDA_00400 9.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NECCCLDA_00401 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NECCCLDA_00402 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NECCCLDA_00403 4.6e-35 yrhC S YrhC-like protein
NECCCLDA_00404 1.4e-78 yrhD S Protein of unknown function (DUF1641)
NECCCLDA_00405 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NECCCLDA_00406 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
NECCCLDA_00407 1.8e-142 focA P Formate nitrite
NECCCLDA_00410 7.2e-95 yrhH Q methyltransferase
NECCCLDA_00411 3.3e-101 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NECCCLDA_00412 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NECCCLDA_00413 1.2e-43 yrhK S YrhK-like protein
NECCCLDA_00414 0.0 yrhL I Acyltransferase family
NECCCLDA_00415 6.1e-149 rsiV S Protein of unknown function (DUF3298)
NECCCLDA_00416 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NECCCLDA_00417 4.1e-150 yrhO K Archaeal transcriptional regulator TrmB
NECCCLDA_00418 3.6e-106 yrhP E LysE type translocator
NECCCLDA_00419 3.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NECCCLDA_00420 0.0 levR K PTS system fructose IIA component
NECCCLDA_00421 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
NECCCLDA_00422 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NECCCLDA_00423 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NECCCLDA_00424 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NECCCLDA_00425 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NECCCLDA_00426 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
NECCCLDA_00427 2.5e-197 adhA 1.1.1.1 C alcohol dehydrogenase
NECCCLDA_00428 4e-24 yphJ 4.1.1.44 S peroxiredoxin activity
NECCCLDA_00429 4.3e-47 yraB K helix_turn_helix, mercury resistance
NECCCLDA_00430 1.1e-49 yraD M Spore coat protein
NECCCLDA_00431 1.7e-25 yraE
NECCCLDA_00432 1.1e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NECCCLDA_00433 6.4e-63 yraF M Spore coat protein
NECCCLDA_00434 5.3e-37 yraG
NECCCLDA_00435 1.3e-66 E Glyoxalase-like domain
NECCCLDA_00436 2.4e-61 T sh3 domain protein
NECCCLDA_00437 4.9e-60 T sh3 domain protein
NECCCLDA_00438 9.9e-149 S Alpha beta hydrolase
NECCCLDA_00439 3.8e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NECCCLDA_00440 4e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NECCCLDA_00441 1.9e-186 yrpG C Aldo/keto reductase family
NECCCLDA_00442 7.7e-94 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NECCCLDA_00443 8.7e-115 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NECCCLDA_00444 1.8e-65 napB K MarR family transcriptional regulator
NECCCLDA_00445 3.2e-219 yfjF U Belongs to the major facilitator superfamily
NECCCLDA_00447 1.8e-137 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
NECCCLDA_00448 7.7e-153 2.2.1.1 G Transketolase, pyrimidine binding domain
NECCCLDA_00449 1.1e-112 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECCCLDA_00450 3e-211 rbtT P Major Facilitator Superfamily
NECCCLDA_00452 2.5e-100 K helix_turn_helix gluconate operon transcriptional repressor
NECCCLDA_00453 8.7e-125 yrpD S Domain of unknown function, YrpD
NECCCLDA_00454 1.9e-144 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NECCCLDA_00455 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NECCCLDA_00456 7.2e-166 aadK G Streptomycin adenylyltransferase
NECCCLDA_00457 1.4e-89 yrdA S DinB family
NECCCLDA_00458 1.5e-54 S Protein of unknown function (DUF2568)
NECCCLDA_00459 1e-99 yrdC 3.5.1.19 Q Isochorismatase family
NECCCLDA_00460 5.2e-226 cypA C Cytochrome P450
NECCCLDA_00462 2.6e-40 yrdF K ribonuclease inhibitor
NECCCLDA_00463 5.3e-78 bkdR K helix_turn_helix ASNC type
NECCCLDA_00464 2.8e-137 azlC E AzlC protein
NECCCLDA_00465 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NECCCLDA_00466 9.5e-226 brnQ E Component of the transport system for branched-chain amino acids
NECCCLDA_00467 7.7e-153 czcD P COG1230 Co Zn Cd efflux system component
NECCCLDA_00468 3.3e-197 trkA P Oxidoreductase
NECCCLDA_00469 3.9e-159 yrdQ K Transcriptional regulator
NECCCLDA_00470 1.7e-168 yrdR EG EamA-like transporter family
NECCCLDA_00471 8.7e-16 S YrzO-like protein
NECCCLDA_00472 3.7e-230 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NECCCLDA_00473 9.1e-83 bltD 2.3.1.57 K FR47-like protein
NECCCLDA_00474 1.1e-209 blt EGP Major facilitator Superfamily
NECCCLDA_00475 5.8e-149 bltR K helix_turn_helix, mercury resistance
NECCCLDA_00477 1.4e-106 yrkC G Cupin domain
NECCCLDA_00478 7.8e-39 yrkD S protein conserved in bacteria
NECCCLDA_00479 2.5e-83 yrkE O DsrE/DsrF/DrsH-like family
NECCCLDA_00480 4.9e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
NECCCLDA_00481 3.3e-211 yrkH P Rhodanese Homology Domain
NECCCLDA_00482 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
NECCCLDA_00483 2.6e-114 yrkJ S membrane transporter protein
NECCCLDA_00484 1.7e-79 S Protein of unknown function with HXXEE motif
NECCCLDA_00485 5.7e-97 ywrO S Flavodoxin-like fold
NECCCLDA_00486 2.3e-104 yrkN K Acetyltransferase (GNAT) family
NECCCLDA_00487 1.4e-223 yrkO P Protein of unknown function (DUF418)
NECCCLDA_00488 2.6e-126 T Transcriptional regulator
NECCCLDA_00489 3.8e-235 yrkQ T Histidine kinase
NECCCLDA_00490 2e-68 psiE S Protein PsiE homolog
NECCCLDA_00491 1.4e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NECCCLDA_00493 6.4e-96 adk 2.7.4.3 F adenylate kinase activity
NECCCLDA_00494 7.9e-89 K Transcriptional regulator PadR-like family
NECCCLDA_00495 2.9e-159 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
NECCCLDA_00498 1e-70 rusA L Endodeoxyribonuclease RusA
NECCCLDA_00499 3.6e-31 yqaO S Phage-like element PBSX protein XtrA
NECCCLDA_00501 1.3e-27 S phage terminase, large subunit
NECCCLDA_00502 2.1e-122 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NECCCLDA_00504 2.3e-273 L nucleic acid phosphodiester bond hydrolysis
NECCCLDA_00506 8.7e-58 S TraX protein
NECCCLDA_00508 6.3e-92 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NECCCLDA_00509 1.4e-90 lacR K Transcriptional regulator
NECCCLDA_00510 1e-70 K MerR family transcriptional regulator
NECCCLDA_00511 3.3e-139 yvgN 1.1.1.346 S Reductase
NECCCLDA_00512 4.9e-130 S Aspartate phosphatase response regulator
NECCCLDA_00514 4.9e-114 M1-798 KP helix_turn_helix, Arsenical Resistance Operon Repressor
NECCCLDA_00515 8.4e-43 P Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NECCCLDA_00516 4.8e-206 ydeG EGP Major facilitator superfamily
NECCCLDA_00518 6e-121 tyrB 2.6.1.1, 2.6.1.57 E Aminotransferase, class I
NECCCLDA_00519 1.2e-76 6.2.1.3 H PFAM Dimethylmenaquinone methyltransferase
NECCCLDA_00520 2.1e-61 dlpA H Aldolase/RraA
NECCCLDA_00521 5.8e-83 H PFAM Dimethylmenaquinone methyltransferase
NECCCLDA_00522 9.4e-46 K regulatory protein GntR HTH
NECCCLDA_00523 1.8e-83 E LysE type translocator
NECCCLDA_00524 2.6e-142 yfiE K LysR substrate binding domain
NECCCLDA_00525 1.1e-278 cisA2 L Recombinase
NECCCLDA_00526 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NECCCLDA_00527 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
NECCCLDA_00528 1.7e-131 yqeB
NECCCLDA_00529 1.4e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NECCCLDA_00530 3e-105 yqeD S SNARE associated Golgi protein
NECCCLDA_00531 8.9e-136 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NECCCLDA_00532 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
NECCCLDA_00534 5.3e-95 yqeG S hydrolase of the HAD superfamily
NECCCLDA_00535 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NECCCLDA_00536 1.7e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NECCCLDA_00537 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NECCCLDA_00538 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NECCCLDA_00539 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NECCCLDA_00540 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NECCCLDA_00541 2.5e-138 yqeM Q Methyltransferase
NECCCLDA_00542 5.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NECCCLDA_00543 3.9e-97 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NECCCLDA_00544 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
NECCCLDA_00545 0.0 comEC S Competence protein ComEC
NECCCLDA_00546 4.1e-15 S YqzM-like protein
NECCCLDA_00547 2.8e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
NECCCLDA_00548 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NECCCLDA_00549 1.5e-203 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NECCCLDA_00550 2.6e-222 spoIIP M stage II sporulation protein P
NECCCLDA_00551 6.8e-51 yqxA S Protein of unknown function (DUF3679)
NECCCLDA_00552 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NECCCLDA_00553 2.9e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
NECCCLDA_00554 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NECCCLDA_00555 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NECCCLDA_00556 0.0 dnaK O Heat shock 70 kDa protein
NECCCLDA_00557 3.6e-181 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NECCCLDA_00558 4.6e-174 prmA J Methylates ribosomal protein L11
NECCCLDA_00559 2.1e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NECCCLDA_00560 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NECCCLDA_00561 4.1e-157 yqeW P COG1283 Na phosphate symporter
NECCCLDA_00562 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NECCCLDA_00563 2.5e-61 yqeY S Yqey-like protein
NECCCLDA_00564 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NECCCLDA_00565 4.3e-122 yqfA S UPF0365 protein
NECCCLDA_00566 5.1e-24 yqfB
NECCCLDA_00567 2.7e-45 yqfC S sporulation protein YqfC
NECCCLDA_00568 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NECCCLDA_00569 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
NECCCLDA_00571 0.0 yqfF S membrane-associated HD superfamily hydrolase
NECCCLDA_00572 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NECCCLDA_00573 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NECCCLDA_00574 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NECCCLDA_00575 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NECCCLDA_00576 8.4e-19 S YqzL-like protein
NECCCLDA_00577 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
NECCCLDA_00578 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NECCCLDA_00579 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NECCCLDA_00580 4.5e-112 ccpN K CBS domain
NECCCLDA_00581 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NECCCLDA_00582 7.7e-88 yaiI S Belongs to the UPF0178 family
NECCCLDA_00583 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NECCCLDA_00584 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NECCCLDA_00585 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NECCCLDA_00586 2e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
NECCCLDA_00587 1.4e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NECCCLDA_00588 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NECCCLDA_00589 2.1e-12 yqfQ S YqfQ-like protein
NECCCLDA_00590 1.5e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NECCCLDA_00591 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NECCCLDA_00592 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NECCCLDA_00593 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NECCCLDA_00594 7.1e-77 zur P Belongs to the Fur family
NECCCLDA_00595 2.3e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NECCCLDA_00596 4.3e-62 yqfX S membrane
NECCCLDA_00597 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NECCCLDA_00598 5.8e-46 yqfZ M LysM domain
NECCCLDA_00599 3.9e-131 yqgB S Protein of unknown function (DUF1189)
NECCCLDA_00600 4e-73 yqgC S protein conserved in bacteria
NECCCLDA_00601 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NECCCLDA_00602 5.6e-231 yqgE EGP Major facilitator superfamily
NECCCLDA_00603 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NECCCLDA_00604 2.6e-150 pstS P Phosphate
NECCCLDA_00605 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NECCCLDA_00606 6.3e-157 pstA P Phosphate transport system permease
NECCCLDA_00607 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NECCCLDA_00608 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NECCCLDA_00609 7.3e-72 yqzC S YceG-like family
NECCCLDA_00610 9.2e-51 yqzD
NECCCLDA_00612 4.2e-195 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NECCCLDA_00613 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NECCCLDA_00614 4.3e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NECCCLDA_00615 2.5e-09 yqgO
NECCCLDA_00616 9.8e-259 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NECCCLDA_00617 3.1e-33 yqgQ S Protein conserved in bacteria
NECCCLDA_00618 4.4e-180 glcK 2.7.1.2 G Glucokinase
NECCCLDA_00619 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NECCCLDA_00620 1.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NECCCLDA_00621 1.1e-197 yqgU
NECCCLDA_00622 6.9e-50 yqgV S Thiamine-binding protein
NECCCLDA_00623 8.9e-23 yqgW S Protein of unknown function (DUF2759)
NECCCLDA_00624 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NECCCLDA_00625 1.8e-37 yqgY S Protein of unknown function (DUF2626)
NECCCLDA_00626 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NECCCLDA_00628 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NECCCLDA_00629 1.5e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NECCCLDA_00630 1.4e-173 corA P Mg2 transporter protein
NECCCLDA_00633 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NECCCLDA_00634 8.7e-174 comGB NU COG1459 Type II secretory pathway, component PulF
NECCCLDA_00635 1.4e-47 comGC U Required for transformation and DNA binding
NECCCLDA_00636 1e-67 gspH NU protein transport across the cell outer membrane
NECCCLDA_00637 3.1e-59 comGE
NECCCLDA_00638 4.1e-46 comGF U Putative Competence protein ComGF
NECCCLDA_00639 3.4e-43 S ComG operon protein 7
NECCCLDA_00640 5.2e-26 yqzE S YqzE-like protein
NECCCLDA_00641 2.6e-52 yqzG S Protein of unknown function (DUF3889)
NECCCLDA_00642 1.3e-110 yqxM
NECCCLDA_00643 6.7e-59 sipW 3.4.21.89 U Signal peptidase
NECCCLDA_00644 8.6e-142 tasA S Cell division protein FtsN
NECCCLDA_00645 1e-54 sinR K transcriptional
NECCCLDA_00646 3.6e-24 sinI S Anti-repressor SinI
NECCCLDA_00647 2.3e-150 yqhG S Bacterial protein YqhG of unknown function
NECCCLDA_00648 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NECCCLDA_00649 8.1e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NECCCLDA_00650 7.1e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NECCCLDA_00651 1.1e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NECCCLDA_00652 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
NECCCLDA_00653 7.5e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NECCCLDA_00654 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NECCCLDA_00655 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
NECCCLDA_00656 2.2e-61 yqhP
NECCCLDA_00657 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
NECCCLDA_00658 2.3e-93 yqhR S Conserved membrane protein YqhR
NECCCLDA_00659 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NECCCLDA_00660 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NECCCLDA_00661 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NECCCLDA_00662 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NECCCLDA_00663 4e-170 spoIIIAA S stage III sporulation protein AA
NECCCLDA_00664 4.1e-84 spoIIIAB S Stage III sporulation protein
NECCCLDA_00665 7.6e-29 spoIIIAC S stage III sporulation protein AC
NECCCLDA_00666 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NECCCLDA_00667 1.3e-197 spoIIIAE S stage III sporulation protein AE
NECCCLDA_00668 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NECCCLDA_00669 2.2e-109 spoIIIAG S stage III sporulation protein AG
NECCCLDA_00670 9.9e-91 spoIIIAH S SpoIIIAH-like protein
NECCCLDA_00671 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NECCCLDA_00672 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NECCCLDA_00673 2.1e-67 yqhY S protein conserved in bacteria
NECCCLDA_00674 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NECCCLDA_00675 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NECCCLDA_00676 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NECCCLDA_00677 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NECCCLDA_00678 2.2e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NECCCLDA_00679 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NECCCLDA_00680 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NECCCLDA_00681 8.6e-78 argR K Regulates arginine biosynthesis genes
NECCCLDA_00682 3e-296 recN L May be involved in recombinational repair of damaged DNA
NECCCLDA_00683 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
NECCCLDA_00684 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NECCCLDA_00686 3.6e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NECCCLDA_00687 5.9e-27
NECCCLDA_00688 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NECCCLDA_00689 9.2e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NECCCLDA_00690 3.8e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
NECCCLDA_00691 2.4e-153 hbdA 1.1.1.157 I Dehydrogenase
NECCCLDA_00692 1.7e-210 mmgC I acyl-CoA dehydrogenase
NECCCLDA_00693 6.4e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NECCCLDA_00694 1.1e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NECCCLDA_00695 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NECCCLDA_00696 4e-34 yqzF S Protein of unknown function (DUF2627)
NECCCLDA_00697 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NECCCLDA_00698 2.1e-155 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NECCCLDA_00699 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NECCCLDA_00700 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NECCCLDA_00701 8.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NECCCLDA_00702 5.5e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NECCCLDA_00703 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NECCCLDA_00704 1.2e-217 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NECCCLDA_00705 7.5e-152 bmrR K helix_turn_helix, mercury resistance
NECCCLDA_00706 7.9e-208 norA EGP Major facilitator Superfamily
NECCCLDA_00707 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NECCCLDA_00708 9.3e-77 yqiW S Belongs to the UPF0403 family
NECCCLDA_00709 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
NECCCLDA_00710 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NECCCLDA_00711 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NECCCLDA_00712 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
NECCCLDA_00713 3e-98 yqjB S protein conserved in bacteria
NECCCLDA_00715 1e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NECCCLDA_00716 3.6e-285 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NECCCLDA_00717 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NECCCLDA_00718 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
NECCCLDA_00719 1.5e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NECCCLDA_00720 4.5e-24 yqzJ
NECCCLDA_00721 1.1e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NECCCLDA_00722 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NECCCLDA_00723 3.3e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NECCCLDA_00724 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NECCCLDA_00725 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NECCCLDA_00726 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NECCCLDA_00727 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NECCCLDA_00728 0.0 rocB E arginine degradation protein
NECCCLDA_00729 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NECCCLDA_00730 4.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NECCCLDA_00731 2.9e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NECCCLDA_00732 5.4e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NECCCLDA_00733 7e-178 coaA 2.7.1.33 F Pantothenic acid kinase
NECCCLDA_00734 4.6e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NECCCLDA_00736 3.8e-224 yqjV G Major Facilitator Superfamily
NECCCLDA_00738 2.9e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NECCCLDA_00739 1.7e-49 S YolD-like protein
NECCCLDA_00740 1.8e-86 yqjY K acetyltransferase
NECCCLDA_00741 6.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NECCCLDA_00742 2.8e-193 yqkA K GrpB protein
NECCCLDA_00743 2.8e-54 yqkB S Belongs to the HesB IscA family
NECCCLDA_00744 4.6e-38 yqkC S Protein of unknown function (DUF2552)
NECCCLDA_00745 2.4e-170 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NECCCLDA_00746 3.1e-12 yqkE S Protein of unknown function (DUF3886)
NECCCLDA_00747 9.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NECCCLDA_00749 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NECCCLDA_00750 2.9e-218 yqxK 3.6.4.12 L DNA helicase
NECCCLDA_00751 4.5e-58 ansR K Transcriptional regulator
NECCCLDA_00752 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
NECCCLDA_00753 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NECCCLDA_00754 9.1e-235 mleN C Na H antiporter
NECCCLDA_00755 5.5e-242 mleA 1.1.1.38 C malic enzyme
NECCCLDA_00756 5.5e-30 yqkK
NECCCLDA_00757 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NECCCLDA_00758 2.4e-80 fur P Belongs to the Fur family
NECCCLDA_00759 6.4e-37 S Protein of unknown function (DUF4227)
NECCCLDA_00760 5.9e-155 xerD L recombinase XerD
NECCCLDA_00761 1.3e-229 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NECCCLDA_00762 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NECCCLDA_00763 5.3e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NECCCLDA_00764 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NECCCLDA_00765 3.9e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NECCCLDA_00766 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NECCCLDA_00767 9.6e-112 spoVAA S Stage V sporulation protein AA
NECCCLDA_00768 1e-67 spoVAB S Stage V sporulation protein AB
NECCCLDA_00769 2.3e-78 spoVAC S stage V sporulation protein AC
NECCCLDA_00770 9e-192 spoVAD I Stage V sporulation protein AD
NECCCLDA_00771 2.2e-57 spoVAEB S stage V sporulation protein
NECCCLDA_00772 1.4e-110 spoVAEA S stage V sporulation protein
NECCCLDA_00773 1.4e-273 spoVAF EG Stage V sporulation protein AF
NECCCLDA_00774 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NECCCLDA_00775 8.1e-149 ypuA S Secreted protein
NECCCLDA_00776 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NECCCLDA_00782 2e-36 S Pfam Transposase IS66
NECCCLDA_00783 1.9e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NECCCLDA_00785 3.6e-31 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NECCCLDA_00786 4e-93 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NECCCLDA_00787 7.8e-55 ypuD
NECCCLDA_00788 8.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NECCCLDA_00789 2.2e-114 ribE 2.5.1.9 H Riboflavin synthase
NECCCLDA_00790 7e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NECCCLDA_00791 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NECCCLDA_00792 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NECCCLDA_00793 9.4e-92 ypuF S Domain of unknown function (DUF309)
NECCCLDA_00794 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NECCCLDA_00795 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NECCCLDA_00796 7.6e-97 ypuI S Protein of unknown function (DUF3907)
NECCCLDA_00797 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NECCCLDA_00798 3.5e-103 spmA S Spore maturation protein
NECCCLDA_00799 1.9e-87 spmB S Spore maturation protein
NECCCLDA_00800 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NECCCLDA_00801 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NECCCLDA_00802 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NECCCLDA_00803 1.3e-213 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NECCCLDA_00804 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECCCLDA_00805 0.0 resE 2.7.13.3 T Histidine kinase
NECCCLDA_00806 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NECCCLDA_00807 1.5e-184 rsiX
NECCCLDA_00808 9.4e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NECCCLDA_00809 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NECCCLDA_00810 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NECCCLDA_00811 4.7e-41 fer C Ferredoxin
NECCCLDA_00812 1.8e-198 ypbB 5.1.3.1 S protein conserved in bacteria
NECCCLDA_00813 9.2e-286 recQ 3.6.4.12 L DNA helicase
NECCCLDA_00814 1.1e-99 ypbD S metal-dependent membrane protease
NECCCLDA_00815 1.7e-78 ypbE M Lysin motif
NECCCLDA_00816 2.8e-81 ypbF S Protein of unknown function (DUF2663)
NECCCLDA_00817 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
NECCCLDA_00818 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NECCCLDA_00819 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NECCCLDA_00820 1.3e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NECCCLDA_00821 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
NECCCLDA_00822 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NECCCLDA_00823 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NECCCLDA_00824 6.6e-111 ypfA M Flagellar protein YcgR
NECCCLDA_00825 5e-21 S Family of unknown function (DUF5359)
NECCCLDA_00826 1.2e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NECCCLDA_00827 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NECCCLDA_00828 1.2e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NECCCLDA_00829 1e-07 S YpzI-like protein
NECCCLDA_00830 1.3e-102 yphA
NECCCLDA_00831 2.5e-161 seaA S YIEGIA protein
NECCCLDA_00832 2.3e-27 ypzH
NECCCLDA_00833 1.5e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NECCCLDA_00834 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NECCCLDA_00835 1.6e-18 yphE S Protein of unknown function (DUF2768)
NECCCLDA_00836 1.5e-135 yphF
NECCCLDA_00837 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NECCCLDA_00838 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NECCCLDA_00839 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NECCCLDA_00840 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NECCCLDA_00841 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NECCCLDA_00842 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NECCCLDA_00843 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NECCCLDA_00844 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NECCCLDA_00845 4.2e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NECCCLDA_00846 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NECCCLDA_00847 2e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NECCCLDA_00848 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NECCCLDA_00849 3.4e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NECCCLDA_00850 1.4e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NECCCLDA_00851 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NECCCLDA_00852 1.5e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NECCCLDA_00853 6.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NECCCLDA_00854 5.2e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NECCCLDA_00855 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NECCCLDA_00856 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NECCCLDA_00857 2.2e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NECCCLDA_00858 2.7e-233 S COG0457 FOG TPR repeat
NECCCLDA_00859 2.8e-99 ypiB S Belongs to the UPF0302 family
NECCCLDA_00860 7.2e-77 ypiF S Protein of unknown function (DUF2487)
NECCCLDA_00861 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NECCCLDA_00862 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NECCCLDA_00863 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NECCCLDA_00864 9.9e-98 ypjA S membrane
NECCCLDA_00865 1e-142 ypjB S sporulation protein
NECCCLDA_00866 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NECCCLDA_00867 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NECCCLDA_00868 1.2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NECCCLDA_00869 1.6e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NECCCLDA_00870 3.4e-129 bshB1 S proteins, LmbE homologs
NECCCLDA_00871 4.5e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NECCCLDA_00872 6.6e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NECCCLDA_00873 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NECCCLDA_00874 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NECCCLDA_00875 1.2e-155 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NECCCLDA_00876 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NECCCLDA_00877 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NECCCLDA_00878 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NECCCLDA_00879 2.2e-79 ypmB S protein conserved in bacteria
NECCCLDA_00880 1.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NECCCLDA_00881 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NECCCLDA_00882 5.7e-129 dnaD L DNA replication protein DnaD
NECCCLDA_00883 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NECCCLDA_00884 2.3e-92 ypoC
NECCCLDA_00885 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NECCCLDA_00886 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NECCCLDA_00887 7.7e-185 yppC S Protein of unknown function (DUF2515)
NECCCLDA_00890 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
NECCCLDA_00892 1.2e-48 yppG S YppG-like protein
NECCCLDA_00893 3.6e-70 hspX O Belongs to the small heat shock protein (HSP20) family
NECCCLDA_00894 3.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NECCCLDA_00895 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NECCCLDA_00896 8.1e-235 yprB L RNase_H superfamily
NECCCLDA_00897 6.3e-91 ypsA S Belongs to the UPF0398 family
NECCCLDA_00898 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NECCCLDA_00899 1.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NECCCLDA_00901 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NECCCLDA_00902 5.1e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECCCLDA_00903 1.4e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NECCCLDA_00904 1.5e-186 ptxS K transcriptional
NECCCLDA_00905 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NECCCLDA_00906 4.3e-101 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NECCCLDA_00907 1.6e-169 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NECCCLDA_00908 3.3e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NECCCLDA_00909 7.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NECCCLDA_00910 9.5e-226 pbuX F xanthine
NECCCLDA_00911 2.8e-207 bcsA Q Naringenin-chalcone synthase
NECCCLDA_00912 6.7e-87 ypbQ S protein conserved in bacteria
NECCCLDA_00914 0.0 ypbR S Dynamin family
NECCCLDA_00915 1e-38 ypbS S Protein of unknown function (DUF2533)
NECCCLDA_00916 1.9e-07
NECCCLDA_00917 4.4e-166 polA 2.7.7.7 L 5'3' exonuclease
NECCCLDA_00919 2.7e-67 rnhA 3.1.26.4 L Ribonuclease
NECCCLDA_00920 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NECCCLDA_00921 1.9e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NECCCLDA_00922 3e-29 ypeQ S Zinc-finger
NECCCLDA_00923 1.8e-30 S Protein of unknown function (DUF2564)
NECCCLDA_00924 3.8e-16 degR
NECCCLDA_00925 7.9e-31 cspD K Cold-shock protein
NECCCLDA_00926 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NECCCLDA_00927 1.4e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NECCCLDA_00928 2.8e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NECCCLDA_00929 2.9e-108 ypgQ S phosphohydrolase
NECCCLDA_00930 6.4e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
NECCCLDA_00931 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NECCCLDA_00932 1.7e-75 yphP S Belongs to the UPF0403 family
NECCCLDA_00933 6.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NECCCLDA_00934 7.8e-114 ypjP S YpjP-like protein
NECCCLDA_00935 7.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NECCCLDA_00936 2.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NECCCLDA_00937 3.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NECCCLDA_00938 4.2e-110 hlyIII S protein, Hemolysin III
NECCCLDA_00939 3.4e-183 pspF K Transcriptional regulator
NECCCLDA_00940 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NECCCLDA_00941 3.4e-39 ypmP S Protein of unknown function (DUF2535)
NECCCLDA_00942 7.1e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NECCCLDA_00943 3.7e-137 ypmR E GDSL-like Lipase/Acylhydrolase
NECCCLDA_00944 4.2e-98 ypmS S protein conserved in bacteria
NECCCLDA_00945 1.6e-28 ypmT S Uncharacterized ympT
NECCCLDA_00946 2.2e-222 mepA V MATE efflux family protein
NECCCLDA_00947 1.6e-70 ypoP K transcriptional
NECCCLDA_00948 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NECCCLDA_00949 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NECCCLDA_00950 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
NECCCLDA_00951 1.4e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NECCCLDA_00952 2.2e-176 cgeB S Spore maturation protein
NECCCLDA_00953 3.1e-63 cgeA
NECCCLDA_00954 8.4e-18 cgeC
NECCCLDA_00955 2e-09 cgeC
NECCCLDA_00956 1e-253 cgeD M maturation of the outermost layer of the spore
NECCCLDA_00957 1.7e-142 yiiD K acetyltransferase
NECCCLDA_00959 5.8e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NECCCLDA_00960 1.9e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NECCCLDA_00961 3.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NECCCLDA_00962 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
NECCCLDA_00963 1.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NECCCLDA_00964 4.7e-199 kamA 5.4.3.2 E lysine 2,3-aminomutase
NECCCLDA_00965 1.7e-282 S Recombinase
NECCCLDA_00966 1.7e-80 yhbS S family acetyltransferase
NECCCLDA_00967 1.9e-105 yokF 3.1.31.1 L RNA catabolic process
NECCCLDA_00968 6.1e-16
NECCCLDA_00969 2.4e-66 G SMI1-KNR4 cell-wall
NECCCLDA_00970 2.5e-133 V HNH endonuclease
NECCCLDA_00971 2.7e-173 yobL S Bacterial EndoU nuclease
NECCCLDA_00972 1.2e-79 S SMI1-KNR4 cell-wall
NECCCLDA_00974 2e-08 S Domain of unknown function (DUF4879)
NECCCLDA_00976 5.1e-37
NECCCLDA_00978 1.7e-51 S YolD-like protein
NECCCLDA_00979 1.2e-230 S impB/mucB/samB family C-terminal domain
NECCCLDA_00981 4.1e-206 S aspartate phosphatase
NECCCLDA_00982 9.2e-37 S Bacteriophage holin
NECCCLDA_00984 2.2e-71 S N-acetylmuramoyl-L-alanine amidase activity
NECCCLDA_00985 0.0 G Exopolysaccharide biosynthesis protein
NECCCLDA_00986 4.9e-135
NECCCLDA_00987 4.9e-298 S Pfam Transposase IS66
NECCCLDA_00988 4.2e-82 S Phage tail protein
NECCCLDA_00989 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NECCCLDA_00990 1.4e-108
NECCCLDA_00991 3.2e-17
NECCCLDA_00995 3.7e-190 xerH A Belongs to the 'phage' integrase family
NECCCLDA_00996 5.6e-55
NECCCLDA_00997 1.7e-55
NECCCLDA_00998 3.3e-10 xkdX
NECCCLDA_01000 4.3e-172
NECCCLDA_01001 5.1e-57
NECCCLDA_01004 2.3e-89
NECCCLDA_01005 8.1e-131
NECCCLDA_01006 2.6e-91
NECCCLDA_01007 1.4e-121
NECCCLDA_01009 1.1e-68
NECCCLDA_01010 1.1e-80
NECCCLDA_01011 1.3e-185
NECCCLDA_01012 5.1e-93
NECCCLDA_01013 3.4e-261
NECCCLDA_01014 5e-279
NECCCLDA_01015 0.0 gp17a S Terminase-like family
NECCCLDA_01016 1.8e-175
NECCCLDA_01020 1.3e-197 S Calcineurin-like phosphoesterase superfamily domain
NECCCLDA_01023 4.2e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NECCCLDA_01024 0.0
NECCCLDA_01027 2.1e-203
NECCCLDA_01032 2.5e-08 S Uncharacterised protein family (UPF0715)
NECCCLDA_01033 1.1e-60
NECCCLDA_01036 2.1e-110
NECCCLDA_01037 5.1e-16
NECCCLDA_01038 8.6e-106
NECCCLDA_01043 1.2e-197 L Belongs to the 'phage' integrase family
NECCCLDA_01044 1.6e-260 S DNA-sulfur modification-associated
NECCCLDA_01045 2.7e-177
NECCCLDA_01046 1.1e-33 K Transcriptional regulator
NECCCLDA_01050 1.9e-20
NECCCLDA_01055 1.2e-65
NECCCLDA_01060 3e-90 S Protein of unknown function (DUF1273)
NECCCLDA_01061 5.4e-07 V endonuclease activity
NECCCLDA_01062 2.3e-44
NECCCLDA_01066 4.5e-19 S Hypothetical protein (DUF2513)
NECCCLDA_01067 1.9e-71
NECCCLDA_01068 6.4e-148 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
NECCCLDA_01069 3.6e-128 yoqW S Belongs to the SOS response-associated peptidase family
NECCCLDA_01071 2.7e-187
NECCCLDA_01073 2.2e-143 S Pfam:DUF867
NECCCLDA_01074 0.0 M Parallel beta-helix repeats
NECCCLDA_01078 1.6e-155
NECCCLDA_01079 7.6e-180 L AAA domain
NECCCLDA_01080 1.3e-84
NECCCLDA_01081 1e-284 3.6.4.12 J DnaB-like helicase C terminal domain
NECCCLDA_01082 1e-220 L DNA primase activity
NECCCLDA_01083 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NECCCLDA_01084 0.0 S Bacterial DNA polymerase III alpha subunit
NECCCLDA_01085 5.2e-109 DR0488 S protein conserved in bacteria
NECCCLDA_01090 6e-80 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
NECCCLDA_01092 7.1e-14
NECCCLDA_01093 8.5e-11 cysH 1.8.4.10, 1.8.4.8 EH Phosphoadenosine phosphosulfate reductase
NECCCLDA_01099 3.3e-13
NECCCLDA_01102 2.7e-25 S hydrolase activity
NECCCLDA_01113 5.5e-60 S NrdI Flavodoxin like
NECCCLDA_01114 1.3e-120 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
NECCCLDA_01115 4.7e-215 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
NECCCLDA_01117 1.5e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NECCCLDA_01118 3.7e-35 O Glutaredoxin
NECCCLDA_01119 2.6e-08
NECCCLDA_01120 2.5e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NECCCLDA_01125 4.7e-162 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NECCCLDA_01126 1.5e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NECCCLDA_01129 1.2e-29
NECCCLDA_01130 2.5e-30 sspB S spore protein
NECCCLDA_01140 2.8e-92 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NECCCLDA_01142 3e-08
NECCCLDA_01143 1.8e-62 L Exodeoxyribonuclease III
NECCCLDA_01144 9.2e-72 kamA 5.4.3.2 E lysine 2,3-aminomutase
NECCCLDA_01145 2.9e-47 yokU S YokU-like protein, putative antitoxin
NECCCLDA_01146 1.4e-36 yozE S Belongs to the UPF0346 family
NECCCLDA_01147 6e-123 yodN
NECCCLDA_01149 2.8e-24 yozD S YozD-like protein
NECCCLDA_01150 3.5e-106 yodM 3.6.1.27 I Acid phosphatase homologues
NECCCLDA_01151 3.6e-54 yodL S YodL-like
NECCCLDA_01152 5.3e-09
NECCCLDA_01153 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NECCCLDA_01154 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NECCCLDA_01155 1.5e-23 yodI
NECCCLDA_01156 6.3e-128 yodH Q Methyltransferase
NECCCLDA_01157 5.4e-248 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NECCCLDA_01158 5.1e-257 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NECCCLDA_01159 6.2e-28 S Protein of unknown function (DUF3311)
NECCCLDA_01160 5.5e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
NECCCLDA_01161 4.6e-111 mhqD S Carboxylesterase
NECCCLDA_01162 1.4e-107 yodC C nitroreductase
NECCCLDA_01163 4.4e-55 yodB K transcriptional
NECCCLDA_01164 4.7e-64 yodA S tautomerase
NECCCLDA_01165 7.9e-204 gntP EG COG2610 H gluconate symporter and related permeases
NECCCLDA_01166 2.6e-09
NECCCLDA_01167 8.6e-65 yozR S COG0071 Molecular chaperone (small heat shock protein)
NECCCLDA_01168 1.9e-161 rarD S -transporter
NECCCLDA_01169 1.5e-43
NECCCLDA_01170 2.2e-60 yojF S Protein of unknown function (DUF1806)
NECCCLDA_01171 3.7e-125 yojG S deacetylase
NECCCLDA_01172 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NECCCLDA_01173 9.9e-225 norM V Multidrug efflux pump
NECCCLDA_01175 2.2e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NECCCLDA_01176 2.6e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NECCCLDA_01177 2.1e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NECCCLDA_01178 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NECCCLDA_01179 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
NECCCLDA_01180 0.0 yojO P Von Willebrand factor
NECCCLDA_01181 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NECCCLDA_01182 5.3e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NECCCLDA_01183 5.1e-168 yocS S -transporter
NECCCLDA_01184 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NECCCLDA_01185 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
NECCCLDA_01186 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NECCCLDA_01187 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NECCCLDA_01188 2.7e-31 yozC
NECCCLDA_01189 4.2e-56 yozO S Bacterial PH domain
NECCCLDA_01190 1.9e-36 yocN
NECCCLDA_01191 1.1e-40 yozN
NECCCLDA_01192 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
NECCCLDA_01193 8.1e-32
NECCCLDA_01194 6.4e-54 yocL
NECCCLDA_01195 3.3e-83 dksA T general stress protein
NECCCLDA_01196 8.8e-113 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NECCCLDA_01197 0.0 recQ 3.6.4.12 L DNA helicase
NECCCLDA_01198 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
NECCCLDA_01199 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NECCCLDA_01200 2.3e-196 desK 2.7.13.3 T Histidine kinase
NECCCLDA_01201 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NECCCLDA_01202 9.3e-186 yocD 3.4.17.13 V peptidase S66
NECCCLDA_01203 2.5e-94 yocC
NECCCLDA_01204 6.4e-145
NECCCLDA_01205 1.5e-92 yozB S membrane
NECCCLDA_01206 5.8e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NECCCLDA_01207 1e-51 czrA K transcriptional
NECCCLDA_01208 1e-93 yobW
NECCCLDA_01209 2.1e-171 yobV K WYL domain
NECCCLDA_01210 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
NECCCLDA_01211 3.6e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NECCCLDA_01212 3.3e-98 yobS K Transcriptional regulator
NECCCLDA_01213 4.6e-137 yobR 2.3.1.1 J FR47-like protein
NECCCLDA_01214 2.3e-133 yobQ K helix_turn_helix, arabinose operon control protein
NECCCLDA_01215 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NECCCLDA_01216 2.2e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NECCCLDA_01217 1.2e-100 yokH G SMI1 / KNR4 family
NECCCLDA_01218 1.4e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NECCCLDA_01219 3.3e-28 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NECCCLDA_01220 6.9e-19
NECCCLDA_01222 4e-100 S aspartate phosphatase
NECCCLDA_01224 1.8e-33 yoqW S Belongs to the SOS response-associated peptidase family
NECCCLDA_01225 8.9e-65 yoaQ S Evidence 4 Homologs of previously reported genes of
NECCCLDA_01227 1.1e-116
NECCCLDA_01231 8.8e-37 S TM2 domain
NECCCLDA_01232 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NECCCLDA_01233 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NECCCLDA_01236 1.1e-167 bla 3.5.2.6 V beta-lactamase
NECCCLDA_01237 7.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NECCCLDA_01238 2e-76 yoaW
NECCCLDA_01239 1.9e-158 yijE EG EamA-like transporter family
NECCCLDA_01240 3.3e-158 yoaU K LysR substrate binding domain
NECCCLDA_01241 5.7e-149 yoaT S Protein of unknown function (DUF817)
NECCCLDA_01242 6e-30 yozG K Transcriptional regulator
NECCCLDA_01243 7.3e-75 yoaS S Protein of unknown function (DUF2975)
NECCCLDA_01244 7.1e-172 yoaR V vancomycin resistance protein
NECCCLDA_01245 5e-87
NECCCLDA_01248 2.1e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
NECCCLDA_01251 4.6e-131 yoqW S Belongs to the SOS response-associated peptidase family
NECCCLDA_01252 4.3e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NECCCLDA_01253 2.3e-111 yoaK S Membrane
NECCCLDA_01254 3.2e-132 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NECCCLDA_01255 2.1e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NECCCLDA_01256 9.4e-178 mcpU NT methyl-accepting chemotaxis protein
NECCCLDA_01257 7.7e-35 S Protein of unknown function (DUF4025)
NECCCLDA_01258 7e-14
NECCCLDA_01259 2.2e-07
NECCCLDA_01260 3.3e-90 purR K Transcriptional regulator
NECCCLDA_01261 3.2e-151 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
NECCCLDA_01262 1.4e-204 S Oxidoreductase family, C-terminal alpha/beta domain
NECCCLDA_01263 1.5e-171 iolT EGP Major facilitator Superfamily
NECCCLDA_01264 8.7e-32 yoaF
NECCCLDA_01265 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECCCLDA_01266 2.9e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NECCCLDA_01267 1e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NECCCLDA_01268 9.9e-233 yoaB EGP Major facilitator Superfamily
NECCCLDA_01269 6.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
NECCCLDA_01270 4.8e-139 V AAA domain, putative AbiEii toxin, Type IV TA system
NECCCLDA_01271 6.4e-94 V ABC-2 family transporter protein
NECCCLDA_01272 1.1e-125 V ABC-2 family transporter protein
NECCCLDA_01273 2.9e-96 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NECCCLDA_01274 8e-132 yoxB
NECCCLDA_01275 9.2e-39 yoxC S Bacterial protein of unknown function (DUF948)
NECCCLDA_01276 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NECCCLDA_01277 2.5e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NECCCLDA_01278 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NECCCLDA_01279 1.5e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NECCCLDA_01280 7.8e-155 gltC K Transcriptional regulator
NECCCLDA_01281 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NECCCLDA_01282 5e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NECCCLDA_01283 3e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NECCCLDA_01284 6.3e-154 gltR1 K Transcriptional regulator
NECCCLDA_01285 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NECCCLDA_01286 8.7e-34 yoeD G Helix-turn-helix domain
NECCCLDA_01287 2.2e-96 L Integrase
NECCCLDA_01289 4.1e-98 yoeB S IseA DL-endopeptidase inhibitor
NECCCLDA_01290 2.3e-246 yoeA V MATE efflux family protein
NECCCLDA_01291 4.2e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
NECCCLDA_01292 3.4e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NECCCLDA_01295 2e-08
NECCCLDA_01298 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NECCCLDA_01299 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NECCCLDA_01300 1.8e-37 yaaB S Domain of unknown function (DUF370)
NECCCLDA_01301 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NECCCLDA_01302 2.4e-33 yaaA S S4 domain
NECCCLDA_01303 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NECCCLDA_01304 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NECCCLDA_01305 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NECCCLDA_01306 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NECCCLDA_01307 6.5e-108 jag S single-stranded nucleic acid binding R3H
NECCCLDA_01308 8.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NECCCLDA_01309 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NECCCLDA_01310 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NECCCLDA_01311 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NECCCLDA_01312 1.5e-74 S Bacterial PH domain
NECCCLDA_01313 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NECCCLDA_01314 2.1e-149 spo0J K Belongs to the ParB family
NECCCLDA_01315 1.6e-111 yyaC S Sporulation protein YyaC
NECCCLDA_01316 8.1e-177 yyaD S Membrane
NECCCLDA_01317 2.3e-33 yyzM S protein conserved in bacteria
NECCCLDA_01318 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECCCLDA_01319 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NECCCLDA_01320 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NECCCLDA_01321 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NECCCLDA_01322 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NECCCLDA_01323 4e-144 xth 3.1.11.2 L exodeoxyribonuclease III
NECCCLDA_01324 8.1e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NECCCLDA_01325 1.7e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NECCCLDA_01326 1.1e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NECCCLDA_01327 2.7e-244 EGP Major facilitator superfamily
NECCCLDA_01328 3.6e-168 yyaK S CAAX protease self-immunity
NECCCLDA_01329 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NECCCLDA_01330 2.9e-157 yyaM EG EamA-like transporter family
NECCCLDA_01331 1.5e-60 yyaN K MerR HTH family regulatory protein
NECCCLDA_01332 6.7e-22 yyaR K acetyltransferase
NECCCLDA_01333 1.5e-106 yyaP 1.5.1.3 H RibD C-terminal domain
NECCCLDA_01334 3.5e-66 yyaQ S YjbR
NECCCLDA_01335 7.6e-94 yyaR K Acetyltransferase (GNAT) domain
NECCCLDA_01336 6.5e-97 yyaS S Membrane
NECCCLDA_01337 7.6e-71 yjcF S Acetyltransferase (GNAT) domain
NECCCLDA_01338 5.6e-77 yybA 2.3.1.57 K transcriptional
NECCCLDA_01339 6.2e-125 S Metallo-beta-lactamase superfamily
NECCCLDA_01340 5.7e-52 yybH S SnoaL-like domain
NECCCLDA_01341 5.8e-122
NECCCLDA_01342 1.3e-110 K TipAS antibiotic-recognition domain
NECCCLDA_01343 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NECCCLDA_01345 2.5e-69
NECCCLDA_01346 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NECCCLDA_01347 1.4e-68 ydeP3 K Transcriptional regulator
NECCCLDA_01348 3.9e-84 cotF M Spore coat protein
NECCCLDA_01350 2.9e-160 yybS S membrane
NECCCLDA_01351 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NECCCLDA_01352 2.2e-73 rplI J binds to the 23S rRNA
NECCCLDA_01353 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NECCCLDA_01354 8.4e-221 yeaN P COG2807 Cyanate permease
NECCCLDA_01355 1.9e-15 yycC K YycC-like protein
NECCCLDA_01357 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NECCCLDA_01358 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NECCCLDA_01359 1e-77 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NECCCLDA_01360 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NECCCLDA_01365 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECCCLDA_01366 0.0 vicK 2.7.13.3 T Histidine kinase
NECCCLDA_01367 5.2e-259 yycH S protein conserved in bacteria
NECCCLDA_01368 7.3e-155 yycI S protein conserved in bacteria
NECCCLDA_01369 5.7e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NECCCLDA_01370 3.5e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NECCCLDA_01371 1.4e-256 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NECCCLDA_01372 1.3e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NECCCLDA_01373 5.1e-254 rocE E amino acid
NECCCLDA_01374 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NECCCLDA_01376 2.5e-187 S aspartate phosphatase
NECCCLDA_01377 8.4e-84 yycN 2.3.1.128 K Acetyltransferase
NECCCLDA_01378 1.7e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NECCCLDA_01379 2.4e-217 yycP
NECCCLDA_01380 1.8e-32 yycQ S Protein of unknown function (DUF2651)
NECCCLDA_01382 1.1e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NECCCLDA_01383 3.8e-64
NECCCLDA_01384 1.1e-09 S YyzF-like protein
NECCCLDA_01385 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NECCCLDA_01387 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NECCCLDA_01388 8e-12
NECCCLDA_01389 2.2e-184 S Radical SAM superfamily
NECCCLDA_01390 1.6e-132 yydH O Peptidase M50
NECCCLDA_01391 1e-108 prrC P ABC transporter
NECCCLDA_01392 1.6e-118 S ABC-2 family transporter protein
NECCCLDA_01393 7.6e-13
NECCCLDA_01394 2.5e-124 yydK K Transcriptional regulator
NECCCLDA_01395 3.1e-19 bglF G phosphotransferase system
NECCCLDA_01396 4.1e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECCCLDA_01397 1.2e-188 wgaE S Polysaccharide pyruvyl transferase
NECCCLDA_01398 1.9e-286 ahpF O Alkyl hydroperoxide reductase
NECCCLDA_01399 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NECCCLDA_01400 7.2e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NECCCLDA_01401 8.5e-230 gntP EG COG2610 H gluconate symporter and related permeases
NECCCLDA_01402 1.1e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NECCCLDA_01403 7.3e-127 gntR K transcriptional
NECCCLDA_01404 9.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NECCCLDA_01405 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
NECCCLDA_01406 2.6e-118 yxaC M effector of murein hydrolase
NECCCLDA_01407 7.6e-49 S LrgA family
NECCCLDA_01408 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NECCCLDA_01409 6.6e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NECCCLDA_01410 4.6e-100 yxaF K Transcriptional regulator
NECCCLDA_01411 6.4e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
NECCCLDA_01412 1.2e-222 P Protein of unknown function (DUF418)
NECCCLDA_01413 1.4e-75 yxaI S membrane protein domain
NECCCLDA_01414 1.1e-63 S Family of unknown function (DUF5391)
NECCCLDA_01415 8.3e-91 S PQQ-like domain
NECCCLDA_01416 6.3e-31 yxaI S membrane protein domain
NECCCLDA_01417 2.4e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NECCCLDA_01418 4e-196 yxbF K Bacterial regulatory proteins, tetR family
NECCCLDA_01419 9.6e-102 M HlyD family secretion protein
NECCCLDA_01420 6.1e-238 V Peptidase C39 family
NECCCLDA_01423 7.5e-149 IQ Enoyl-(Acyl carrier protein) reductase
NECCCLDA_01425 0.0 htpG O Molecular chaperone. Has ATPase activity
NECCCLDA_01426 1.1e-243 csbC EGP Major facilitator Superfamily
NECCCLDA_01427 8.3e-48 yxcD S Protein of unknown function (DUF2653)
NECCCLDA_01429 4.1e-175 iolS C Aldo keto reductase
NECCCLDA_01430 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NECCCLDA_01431 3.9e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NECCCLDA_01432 8.7e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NECCCLDA_01433 3.2e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NECCCLDA_01434 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NECCCLDA_01435 1.8e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NECCCLDA_01436 5.1e-235 iolF EGP Major facilitator Superfamily
NECCCLDA_01437 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NECCCLDA_01438 8.6e-167 iolH G Xylose isomerase-like TIM barrel
NECCCLDA_01439 5.6e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NECCCLDA_01440 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NECCCLDA_01441 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECCCLDA_01442 2.9e-179 T PhoQ Sensor
NECCCLDA_01443 2.2e-137 yxdL V ABC transporter, ATP-binding protein
NECCCLDA_01444 0.0 yxdM V ABC transporter (permease)
NECCCLDA_01445 5.9e-58 yxeA S Protein of unknown function (DUF1093)
NECCCLDA_01446 5.6e-175 fhuD P ABC transporter
NECCCLDA_01447 1.4e-68
NECCCLDA_01448 5.6e-16 yxeD
NECCCLDA_01449 1.3e-20 yxeE
NECCCLDA_01452 2.6e-149 yidA S hydrolases of the HAD superfamily
NECCCLDA_01453 6.1e-185 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NECCCLDA_01454 6.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NECCCLDA_01455 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NECCCLDA_01456 3.6e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
NECCCLDA_01457 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
NECCCLDA_01458 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NECCCLDA_01459 5.2e-212 yxeP 3.5.1.47 E hydrolase activity
NECCCLDA_01460 1.1e-250 yxeQ S MmgE/PrpD family
NECCCLDA_01461 3.2e-198 eutH E Ethanolamine utilisation protein, EutH
NECCCLDA_01462 1.7e-151 yxxB S Domain of Unknown Function (DUF1206)
NECCCLDA_01463 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NECCCLDA_01464 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NECCCLDA_01465 1.7e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NECCCLDA_01466 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NECCCLDA_01467 6.1e-252 lysP E amino acid
NECCCLDA_01468 9.1e-178 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NECCCLDA_01469 3.7e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NECCCLDA_01470 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NECCCLDA_01471 1.5e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
NECCCLDA_01472 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NECCCLDA_01473 2.3e-278 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NECCCLDA_01474 2.3e-20 S Domain of unknown function (DUF5082)
NECCCLDA_01475 1.4e-38 yxiC S Family of unknown function (DUF5344)
NECCCLDA_01476 3e-125 S nuclease activity
NECCCLDA_01478 7.3e-19 S Protein conserved in bacteria
NECCCLDA_01480 8.3e-136 S nuclease activity
NECCCLDA_01481 5.5e-53
NECCCLDA_01482 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NECCCLDA_01483 1.6e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECCCLDA_01484 1.1e-72 yxiE T Belongs to the universal stress protein A family
NECCCLDA_01485 1.6e-163 yxxF EG EamA-like transporter family
NECCCLDA_01486 0.0 wapA M COG3209 Rhs family protein
NECCCLDA_01487 7.6e-16 yxiG
NECCCLDA_01488 8.3e-13 yxiG
NECCCLDA_01489 9.1e-137
NECCCLDA_01490 7.9e-85 yxiI S Protein of unknown function (DUF2716)
NECCCLDA_01491 7.7e-43 yxiJ S YxiJ-like protein
NECCCLDA_01494 4.4e-211 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NECCCLDA_01495 1.9e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NECCCLDA_01496 1.2e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
NECCCLDA_01497 6.6e-114
NECCCLDA_01498 3.1e-150 licT K transcriptional antiterminator
NECCCLDA_01499 7.3e-143 exoK GH16 M licheninase activity
NECCCLDA_01500 6.6e-224 citH C Citrate transporter
NECCCLDA_01501 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NECCCLDA_01502 3e-47 yxiS
NECCCLDA_01503 2.2e-101 T Domain of unknown function (DUF4163)
NECCCLDA_01504 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NECCCLDA_01505 3.9e-156 rlmA 2.1.1.187 Q Methyltransferase domain
NECCCLDA_01506 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
NECCCLDA_01507 1.2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NECCCLDA_01508 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NECCCLDA_01509 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NECCCLDA_01510 2.2e-218 yxjG 2.1.1.14 E Methionine synthase
NECCCLDA_01511 9.7e-219 yxjG 2.1.1.14 E Methionine synthase
NECCCLDA_01512 6e-85 yxjI S LURP-one-related
NECCCLDA_01514 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NECCCLDA_01515 4.1e-113 K helix_turn_helix, Lux Regulon
NECCCLDA_01516 4.9e-192 yxjM T Signal transduction histidine kinase
NECCCLDA_01517 2.4e-78 S Protein of unknown function (DUF1453)
NECCCLDA_01518 9.6e-166 yxjO K LysR substrate binding domain
NECCCLDA_01519 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
NECCCLDA_01520 1.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NECCCLDA_01521 4.1e-73 yxkC S Domain of unknown function (DUF4352)
NECCCLDA_01522 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NECCCLDA_01523 4.3e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NECCCLDA_01524 5.4e-164 lrp QT PucR C-terminal helix-turn-helix domain
NECCCLDA_01525 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NECCCLDA_01526 1e-08 P transporter
NECCCLDA_01529 4.3e-155 yxkH G Polysaccharide deacetylase
NECCCLDA_01531 5.1e-309 3.4.24.84 O Peptidase family M48
NECCCLDA_01532 2.7e-228 cimH C COG3493 Na citrate symporter
NECCCLDA_01533 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
NECCCLDA_01534 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NECCCLDA_01535 5.2e-309 cydD V ATP-binding
NECCCLDA_01536 0.0 cydD V ATP-binding protein
NECCCLDA_01537 1.6e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NECCCLDA_01538 1.5e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NECCCLDA_01539 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NECCCLDA_01540 1.9e-47 yxlC S Family of unknown function (DUF5345)
NECCCLDA_01541 1.8e-30
NECCCLDA_01542 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
NECCCLDA_01543 2.8e-165 yxlF V ABC transporter, ATP-binding protein
NECCCLDA_01544 6.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NECCCLDA_01545 7.1e-212 yxlH EGP Major facilitator Superfamily
NECCCLDA_01546 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NECCCLDA_01547 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NECCCLDA_01548 1.1e-19 yxzF
NECCCLDA_01549 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NECCCLDA_01550 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NECCCLDA_01551 1.2e-247 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NECCCLDA_01552 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NECCCLDA_01553 2.4e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NECCCLDA_01554 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NECCCLDA_01555 2.5e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NECCCLDA_01556 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NECCCLDA_01557 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NECCCLDA_01558 8e-232 dltB M membrane protein involved in D-alanine export
NECCCLDA_01559 1.9e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NECCCLDA_01560 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NECCCLDA_01561 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NECCCLDA_01562 3.7e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NECCCLDA_01563 9.8e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NECCCLDA_01564 4e-87 ywaE K Transcriptional regulator
NECCCLDA_01565 1.1e-124 ywaF S Integral membrane protein
NECCCLDA_01566 1.6e-168 gspA M General stress
NECCCLDA_01567 1.2e-152 sacY K transcriptional antiterminator
NECCCLDA_01568 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NECCCLDA_01569 2.6e-272 epr 3.4.21.62 O Belongs to the peptidase S8 family
NECCCLDA_01570 1.1e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NECCCLDA_01571 4.1e-124 ywbB S Protein of unknown function (DUF2711)
NECCCLDA_01572 6.9e-96 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NECCCLDA_01573 7.6e-67 ywbC 4.4.1.5 E glyoxalase
NECCCLDA_01574 1.6e-219 ywbD 2.1.1.191 J Methyltransferase
NECCCLDA_01575 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
NECCCLDA_01576 4.6e-203 ywbF EGP Major facilitator Superfamily
NECCCLDA_01577 2.3e-111 ywbG M effector of murein hydrolase
NECCCLDA_01578 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NECCCLDA_01579 4.3e-153 ywbI K Transcriptional regulator
NECCCLDA_01580 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NECCCLDA_01581 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NECCCLDA_01582 1.5e-253 P COG0672 High-affinity Fe2 Pb2 permease
NECCCLDA_01583 2.9e-186 ycdO P periplasmic lipoprotein involved in iron transport
NECCCLDA_01584 8.4e-224 ywbN P Dyp-type peroxidase family protein
NECCCLDA_01585 2.8e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NECCCLDA_01586 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NECCCLDA_01587 9.8e-49 ywcB S Protein of unknown function, DUF485
NECCCLDA_01589 1.1e-121 ywcC K transcriptional regulator
NECCCLDA_01590 9.5e-60 gtcA S GtrA-like protein
NECCCLDA_01591 6.9e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NECCCLDA_01592 7.8e-304 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NECCCLDA_01593 1e-35 ywzA S membrane
NECCCLDA_01594 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NECCCLDA_01595 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NECCCLDA_01596 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NECCCLDA_01597 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NECCCLDA_01598 1.7e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
NECCCLDA_01599 2.9e-202 rodA D Belongs to the SEDS family
NECCCLDA_01600 1.4e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NECCCLDA_01601 3.6e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NECCCLDA_01602 0.0 vpr O Belongs to the peptidase S8 family
NECCCLDA_01604 1.6e-149 sacT K transcriptional antiterminator
NECCCLDA_01605 1e-139 focA P Formate/nitrite transporter
NECCCLDA_01606 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NECCCLDA_01607 1.9e-291 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NECCCLDA_01608 2e-28 ywdA
NECCCLDA_01609 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NECCCLDA_01610 1.3e-57 pex K Transcriptional regulator PadR-like family
NECCCLDA_01611 5.2e-113 ywdD
NECCCLDA_01613 2.3e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
NECCCLDA_01614 3.3e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NECCCLDA_01615 1.6e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NECCCLDA_01616 1.5e-47 ywdI S Family of unknown function (DUF5327)
NECCCLDA_01617 3.7e-238 ywdJ F Xanthine uracil
NECCCLDA_01618 4.3e-59 ywdK S small membrane protein
NECCCLDA_01619 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NECCCLDA_01620 9.1e-144 spsA M Spore Coat
NECCCLDA_01621 4.7e-268 spsB M Capsule polysaccharide biosynthesis protein
NECCCLDA_01622 6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
NECCCLDA_01623 7.5e-163 spsD 2.3.1.210 K Spore Coat
NECCCLDA_01624 3.2e-214 spsE 2.5.1.56 M acid synthase
NECCCLDA_01625 3.5e-129 spsF M Spore Coat
NECCCLDA_01626 7.9e-188 spsG M Spore Coat
NECCCLDA_01627 2.1e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NECCCLDA_01628 2.5e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NECCCLDA_01629 4.9e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NECCCLDA_01630 6.7e-86 spsL 5.1.3.13 M Spore Coat
NECCCLDA_01631 9.8e-77
NECCCLDA_01632 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NECCCLDA_01633 2.3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NECCCLDA_01634 0.0 rocB E arginine degradation protein
NECCCLDA_01635 7.4e-250 lysP E amino acid
NECCCLDA_01636 6e-206 ywfA EGP Major facilitator Superfamily
NECCCLDA_01637 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NECCCLDA_01638 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NECCCLDA_01639 1.1e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECCCLDA_01640 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NECCCLDA_01641 7.3e-209 bacE EGP Major facilitator Superfamily
NECCCLDA_01642 1.6e-232 ywfG 2.6.1.83 E Aminotransferase class I and II
NECCCLDA_01643 4.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
NECCCLDA_01644 1.1e-146 ywfI C May function as heme-dependent peroxidase
NECCCLDA_01645 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NECCCLDA_01646 1.1e-156 cysL K Transcriptional regulator
NECCCLDA_01647 3.3e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NECCCLDA_01648 1.1e-156 ywfM EG EamA-like transporter family
NECCCLDA_01649 1e-110 rsfA_1
NECCCLDA_01650 3.1e-36 ywzC S Belongs to the UPF0741 family
NECCCLDA_01651 2.1e-254 ywfO S COG1078 HD superfamily phosphohydrolases
NECCCLDA_01652 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
NECCCLDA_01653 5.3e-78 yffB K Transcriptional regulator
NECCCLDA_01654 1e-238 mmr U Major Facilitator Superfamily
NECCCLDA_01656 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NECCCLDA_01657 9.5e-71 ywhA K Transcriptional regulator
NECCCLDA_01658 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NECCCLDA_01659 5.1e-119 ywhC S Peptidase family M50
NECCCLDA_01660 5.2e-95 ywhD S YwhD family
NECCCLDA_01661 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NECCCLDA_01662 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NECCCLDA_01663 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
NECCCLDA_01664 1.2e-49 ywhH S Aminoacyl-tRNA editing domain
NECCCLDA_01666 4.4e-78 S aspartate phosphatase
NECCCLDA_01667 2.5e-189 ywhK CO amine dehydrogenase activity
NECCCLDA_01668 8.6e-246 ywhL CO amine dehydrogenase activity
NECCCLDA_01670 1.7e-248 L Peptidase, M16
NECCCLDA_01671 3e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
NECCCLDA_01672 1.2e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NECCCLDA_01673 1.3e-131 cbiO V ABC transporter
NECCCLDA_01675 4.9e-270 C Fe-S oxidoreductases
NECCCLDA_01676 1e-07 S Bacteriocin subtilosin A
NECCCLDA_01677 4.7e-73 ywiB S protein conserved in bacteria
NECCCLDA_01678 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NECCCLDA_01679 1e-213 narK P COG2223 Nitrate nitrite transporter
NECCCLDA_01680 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
NECCCLDA_01681 5.9e-137 ywiC S YwiC-like protein
NECCCLDA_01682 5.9e-85 arfM T cyclic nucleotide binding
NECCCLDA_01683 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECCCLDA_01684 5.7e-296 narH 1.7.5.1 C Nitrate reductase, beta
NECCCLDA_01685 5.2e-93 narJ 1.7.5.1 C nitrate reductase
NECCCLDA_01686 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
NECCCLDA_01687 3.2e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NECCCLDA_01688 0.0 ywjA V ABC transporter
NECCCLDA_01689 2.4e-95 ywjB H RibD C-terminal domain
NECCCLDA_01690 2.7e-42 ywjC
NECCCLDA_01691 7.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NECCCLDA_01692 2.4e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NECCCLDA_01693 0.0 fadF C COG0247 Fe-S oxidoreductase
NECCCLDA_01694 3.3e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NECCCLDA_01695 1.1e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NECCCLDA_01696 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NECCCLDA_01697 1.8e-90 ywjG S Domain of unknown function (DUF2529)
NECCCLDA_01698 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NECCCLDA_01699 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NECCCLDA_01700 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NECCCLDA_01701 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NECCCLDA_01702 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NECCCLDA_01703 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NECCCLDA_01704 1.1e-32 rpmE J Binds the 23S rRNA
NECCCLDA_01705 7e-104 tdk 2.7.1.21 F thymidine kinase
NECCCLDA_01706 0.0 sfcA 1.1.1.38 C malic enzyme
NECCCLDA_01707 8.6e-160 ywkB S Membrane transport protein
NECCCLDA_01708 6.4e-75 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NECCCLDA_01709 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NECCCLDA_01710 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NECCCLDA_01711 1.2e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NECCCLDA_01713 3.7e-55 ywlA S Uncharacterised protein family (UPF0715)
NECCCLDA_01714 3e-111 spoIIR S stage II sporulation protein R
NECCCLDA_01715 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NECCCLDA_01716 1.8e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NECCCLDA_01717 1.7e-91 mntP P Probably functions as a manganese efflux pump
NECCCLDA_01718 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NECCCLDA_01719 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NECCCLDA_01720 7.2e-95 ywlG S Belongs to the UPF0340 family
NECCCLDA_01721 1.7e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NECCCLDA_01722 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NECCCLDA_01723 2.5e-62 atpI S ATP synthase
NECCCLDA_01724 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NECCCLDA_01725 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NECCCLDA_01726 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NECCCLDA_01727 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NECCCLDA_01728 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NECCCLDA_01729 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NECCCLDA_01730 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NECCCLDA_01731 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NECCCLDA_01732 4.8e-87 ywmA
NECCCLDA_01733 1.3e-32 ywzB S membrane
NECCCLDA_01734 8.2e-134 ywmB S TATA-box binding
NECCCLDA_01735 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NECCCLDA_01736 2.1e-175 spoIID D Stage II sporulation protein D
NECCCLDA_01737 3.9e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NECCCLDA_01738 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NECCCLDA_01740 7.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NECCCLDA_01741 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NECCCLDA_01742 3.5e-104 S response regulator aspartate phosphatase
NECCCLDA_01744 3.8e-84 ywmF S Peptidase M50
NECCCLDA_01745 3.8e-11 csbD K CsbD-like
NECCCLDA_01746 1.4e-21 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NECCCLDA_01747 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NECCCLDA_01748 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NECCCLDA_01749 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NECCCLDA_01750 1.7e-64 ywnA K Transcriptional regulator
NECCCLDA_01751 1.1e-113 ywnB S NAD(P)H-binding
NECCCLDA_01752 2.6e-59 ywnC S Family of unknown function (DUF5362)
NECCCLDA_01753 2.6e-143 mta K transcriptional
NECCCLDA_01754 5.3e-265 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NECCCLDA_01755 2.2e-70 ywnF S Family of unknown function (DUF5392)
NECCCLDA_01756 3.4e-09 ywnC S Family of unknown function (DUF5362)
NECCCLDA_01757 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NECCCLDA_01758 6.9e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NECCCLDA_01759 5.1e-72 ywnJ S VanZ like family
NECCCLDA_01760 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NECCCLDA_01761 1.6e-58 nrgB K Belongs to the P(II) protein family
NECCCLDA_01762 4.3e-225 amt P Ammonium transporter
NECCCLDA_01763 2.2e-76
NECCCLDA_01764 4e-104 phzA Q Isochorismatase family
NECCCLDA_01765 9.8e-242 ywoD EGP Major facilitator superfamily
NECCCLDA_01766 3.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NECCCLDA_01767 1.4e-230 ywoF P Right handed beta helix region
NECCCLDA_01768 7.8e-211 ywoG EGP Major facilitator Superfamily
NECCCLDA_01769 2.1e-70 ywoH K COG1846 Transcriptional regulators
NECCCLDA_01770 3e-44 spoIIID K Stage III sporulation protein D
NECCCLDA_01771 3.5e-180 mbl D Rod shape-determining protein
NECCCLDA_01772 1.5e-125 flhO N flagellar basal body
NECCCLDA_01773 2.6e-141 flhP N flagellar basal body
NECCCLDA_01774 2.2e-196 S aspartate phosphatase
NECCCLDA_01775 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NECCCLDA_01776 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NECCCLDA_01777 0.0 ywpD T PhoQ Sensor
NECCCLDA_01778 3.1e-174 M1-574 T Transcriptional regulatory protein, C terminal
NECCCLDA_01779 0.0 M1-568 M cell wall anchor domain
NECCCLDA_01780 1.9e-83 srtA 3.4.22.70 M Sortase family
NECCCLDA_01781 1.1e-66 ywpF S YwpF-like protein
NECCCLDA_01782 1.3e-66 ywpG
NECCCLDA_01783 3.7e-57 ssbB L Single-stranded DNA-binding protein
NECCCLDA_01784 3.4e-138 glcR K COG1349 Transcriptional regulators of sugar metabolism
NECCCLDA_01785 1.8e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NECCCLDA_01786 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NECCCLDA_01787 8.7e-306 ywqB S SWIM zinc finger
NECCCLDA_01788 1.2e-17
NECCCLDA_01789 2e-116 ywqC M biosynthesis protein
NECCCLDA_01790 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NECCCLDA_01791 2.5e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NECCCLDA_01792 5.2e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NECCCLDA_01793 1.4e-152 ywqG S Domain of unknown function (DUF1963)
NECCCLDA_01794 3.3e-15 S Domain of unknown function (DUF5082)
NECCCLDA_01795 1.3e-38 ywqI S Family of unknown function (DUF5344)
NECCCLDA_01796 1.4e-249 ywqJ S Pre-toxin TG
NECCCLDA_01797 1.4e-47
NECCCLDA_01798 1.7e-50
NECCCLDA_01800 1.7e-07
NECCCLDA_01801 2.6e-53
NECCCLDA_01802 2.6e-121 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NECCCLDA_01803 3.2e-161 K Transcriptional regulator
NECCCLDA_01804 3.3e-100 ywqN S NAD(P)H-dependent
NECCCLDA_01806 6.4e-88 ywrA P COG2059 Chromate transport protein ChrA
NECCCLDA_01807 3.5e-103 ywrB P Chromate transporter
NECCCLDA_01808 8e-82 ywrC K Transcriptional regulator
NECCCLDA_01809 8.8e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NECCCLDA_01810 2.5e-53 S Domain of unknown function (DUF4181)
NECCCLDA_01811 3.4e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NECCCLDA_01812 1.3e-12
NECCCLDA_01813 6.2e-207 cotH M Spore Coat
NECCCLDA_01814 5.1e-124 cotB
NECCCLDA_01815 4.5e-123 ywrJ
NECCCLDA_01816 4.6e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NECCCLDA_01817 1.1e-169 alsR K LysR substrate binding domain
NECCCLDA_01818 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NECCCLDA_01819 6.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NECCCLDA_01820 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NECCCLDA_01821 8e-48 ywsA S Protein of unknown function (DUF3892)
NECCCLDA_01822 8.7e-93 batE T Sh3 type 3 domain protein
NECCCLDA_01823 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NECCCLDA_01824 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
NECCCLDA_01825 6.2e-274 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NECCCLDA_01826 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NECCCLDA_01827 1.8e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NECCCLDA_01828 9.3e-178 rbsR K transcriptional
NECCCLDA_01829 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NECCCLDA_01830 8.6e-70 pgsC S biosynthesis protein
NECCCLDA_01831 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NECCCLDA_01832 3.6e-21 ywtC
NECCCLDA_01833 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NECCCLDA_01834 4.2e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NECCCLDA_01835 7e-141 ywtF K Transcriptional regulator
NECCCLDA_01836 1.3e-246 ywtG EGP Major facilitator Superfamily
NECCCLDA_01837 1.1e-198 gerAC S Spore germination protein
NECCCLDA_01838 5.6e-187 gerBB E Spore germination protein
NECCCLDA_01839 2.2e-244 gerBA EG Spore germination protein
NECCCLDA_01840 4.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NECCCLDA_01841 8.9e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NECCCLDA_01842 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NECCCLDA_01843 2.2e-88 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NECCCLDA_01844 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NECCCLDA_01845 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NECCCLDA_01846 6e-95 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NECCCLDA_01847 1.6e-87 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NECCCLDA_01848 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NECCCLDA_01849 1.1e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NECCCLDA_01850 5.3e-240 ggaA M Glycosyltransferase like family 2
NECCCLDA_01851 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NECCCLDA_01852 1e-132 tagG GM Transport permease protein
NECCCLDA_01853 8.3e-269 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NECCCLDA_01854 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NECCCLDA_01855 8.3e-23 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NECCCLDA_01856 1.9e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NECCCLDA_01857 3.5e-88 M Glycosyltransferase like family 2
NECCCLDA_01858 2.2e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NECCCLDA_01859 5.9e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NECCCLDA_01860 1e-11
NECCCLDA_01861 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NECCCLDA_01862 2.5e-206 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NECCCLDA_01863 1.9e-94 M Glycosyltransferase like family 2
NECCCLDA_01864 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NECCCLDA_01865 3.7e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NECCCLDA_01866 1.5e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NECCCLDA_01867 1.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NECCCLDA_01868 1.4e-262 tuaE M Teichuronic acid biosynthesis protein
NECCCLDA_01869 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
NECCCLDA_01870 1.4e-144 tuaG GT2 M Glycosyltransferase like family 2
NECCCLDA_01871 1.9e-233 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NECCCLDA_01872 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NECCCLDA_01873 2.3e-162 yvhJ K Transcriptional regulator
NECCCLDA_01874 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NECCCLDA_01875 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NECCCLDA_01876 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NECCCLDA_01877 2.1e-154 degV S protein conserved in bacteria
NECCCLDA_01878 1.1e-264 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NECCCLDA_01879 5.7e-46 comFB S Late competence development protein ComFB
NECCCLDA_01880 1.2e-126 comFC S Phosphoribosyl transferase domain
NECCCLDA_01881 7e-74 yvyF S flagellar protein
NECCCLDA_01882 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
NECCCLDA_01883 4.1e-78 flgN NOU FlgN protein
NECCCLDA_01884 1.2e-264 flgK N flagellar hook-associated protein
NECCCLDA_01885 7.8e-155 flgL N Belongs to the bacterial flagellin family
NECCCLDA_01886 2.2e-49 yviE
NECCCLDA_01887 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NECCCLDA_01888 9.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NECCCLDA_01889 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NECCCLDA_01890 6.1e-57 flaG N flagellar protein FlaG
NECCCLDA_01891 3.7e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NECCCLDA_01892 2.9e-69 fliS N flagellar protein FliS
NECCCLDA_01893 1.9e-08 fliT S bacterial-type flagellum organization
NECCCLDA_01894 1.8e-65
NECCCLDA_01895 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NECCCLDA_01896 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NECCCLDA_01897 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NECCCLDA_01898 7.9e-141 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NECCCLDA_01899 1e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
NECCCLDA_01900 1.6e-123 ftsE D cell division ATP-binding protein FtsE
NECCCLDA_01901 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NECCCLDA_01902 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NECCCLDA_01903 5.3e-56 swrA S Swarming motility protein
NECCCLDA_01904 3.2e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NECCCLDA_01905 1.3e-225 yvkA EGP Major facilitator Superfamily
NECCCLDA_01906 7e-101 yvkB K Transcriptional regulator
NECCCLDA_01907 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NECCCLDA_01908 1.2e-30 csbA S protein conserved in bacteria
NECCCLDA_01909 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NECCCLDA_01910 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NECCCLDA_01911 9.2e-78 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NECCCLDA_01912 5.7e-33 yvkN
NECCCLDA_01913 1.8e-48 yvlA
NECCCLDA_01914 2.4e-166 yvlB S Putative adhesin
NECCCLDA_01915 2.6e-26 pspB KT PspC domain
NECCCLDA_01916 1.2e-50 yvlD S Membrane
NECCCLDA_01917 2.7e-203 yvmA EGP Major facilitator Superfamily
NECCCLDA_01918 2e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
NECCCLDA_01919 3e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NECCCLDA_01920 1.2e-34 cypX 1.14.15.13 C Cytochrome P450
NECCCLDA_01921 3.9e-173 cypX 1.14.15.13 C Cytochrome P450
NECCCLDA_01922 9.5e-72 adcR K helix_turn_helix multiple antibiotic resistance protein
NECCCLDA_01923 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NECCCLDA_01924 3.6e-134 yvoA K transcriptional
NECCCLDA_01925 3.2e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NECCCLDA_01926 1.6e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NECCCLDA_01927 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NECCCLDA_01928 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NECCCLDA_01929 8.1e-163 yvoD P COG0370 Fe2 transport system protein B
NECCCLDA_01930 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NECCCLDA_01931 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NECCCLDA_01932 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NECCCLDA_01933 1e-139 yvpB NU protein conserved in bacteria
NECCCLDA_01934 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NECCCLDA_01935 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NECCCLDA_01936 1.7e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NECCCLDA_01937 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NECCCLDA_01938 2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NECCCLDA_01939 3e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NECCCLDA_01940 4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NECCCLDA_01941 8.3e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NECCCLDA_01942 9.9e-76
NECCCLDA_01943 0.0
NECCCLDA_01945 0.0 msbA2 3.6.3.44 V ABC transporter
NECCCLDA_01946 6.5e-276 S COG0457 FOG TPR repeat
NECCCLDA_01947 2.5e-91 usp CBM50 M protein conserved in bacteria
NECCCLDA_01948 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NECCCLDA_01949 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NECCCLDA_01950 1.7e-165 rapZ S Displays ATPase and GTPase activities
NECCCLDA_01951 2.1e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NECCCLDA_01952 1.4e-170 whiA K May be required for sporulation
NECCCLDA_01953 1.6e-36 crh G Phosphocarrier protein Chr
NECCCLDA_01954 2.9e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NECCCLDA_01955 1.8e-33
NECCCLDA_01956 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECCCLDA_01957 9.8e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NECCCLDA_01958 5.6e-141 yvcR V ABC transporter, ATP-binding protein
NECCCLDA_01959 0.0 yxdM V ABC transporter (permease)
NECCCLDA_01960 4.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NECCCLDA_01961 8.2e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NECCCLDA_01962 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NECCCLDA_01963 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
NECCCLDA_01964 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NECCCLDA_01965 8.8e-173 yvdE K Transcriptional regulator
NECCCLDA_01966 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NECCCLDA_01967 1.2e-233 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NECCCLDA_01968 4.5e-244 malC P COG1175 ABC-type sugar transport systems, permease components
NECCCLDA_01969 9.5e-147 malD P transport
NECCCLDA_01970 1e-154 malA S Protein of unknown function (DUF1189)
NECCCLDA_01971 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NECCCLDA_01972 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NECCCLDA_01973 9.1e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NECCCLDA_01974 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NECCCLDA_01976 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
NECCCLDA_01977 4.1e-50 sugE P Small Multidrug Resistance protein
NECCCLDA_01978 4.3e-50 ykkC P Small Multidrug Resistance protein
NECCCLDA_01979 2.6e-106 yvdT K Transcriptional regulator
NECCCLDA_01980 1.8e-295 yveA E amino acid
NECCCLDA_01981 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NECCCLDA_01982 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NECCCLDA_01983 3.3e-258 pbpE V Beta-lactamase
NECCCLDA_01984 2.2e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NECCCLDA_01985 5.8e-74 MA20_18690 S Protein of unknown function (DUF3237)
NECCCLDA_01986 5.1e-92 padC Q Phenolic acid decarboxylase
NECCCLDA_01988 9.4e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NECCCLDA_01989 6.3e-76 slr K transcriptional
NECCCLDA_01990 4e-122 ywqC M biosynthesis protein
NECCCLDA_01991 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NECCCLDA_01992 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NECCCLDA_01993 2.9e-223 epsD GT4 M Glycosyl transferase 4-like
NECCCLDA_01994 1.6e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NECCCLDA_01995 9.2e-217 epsF GT4 M Glycosyl transferases group 1
NECCCLDA_01996 2.4e-206 epsG S EpsG family
NECCCLDA_01997 2e-194 epsH GT2 S Glycosyltransferase like family 2
NECCCLDA_01998 9.2e-203 epsI GM pyruvyl transferase
NECCCLDA_01999 8.9e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NECCCLDA_02000 4.5e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NECCCLDA_02001 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NECCCLDA_02002 4.6e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NECCCLDA_02003 8.4e-218 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NECCCLDA_02004 3e-184 yvfF GM Exopolysaccharide biosynthesis protein
NECCCLDA_02005 1e-31 yvfG S YvfG protein
NECCCLDA_02006 2.7e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NECCCLDA_02007 1.3e-307 yvfH C L-lactate permease
NECCCLDA_02008 1e-112 yvfI K COG2186 Transcriptional regulators
NECCCLDA_02009 1.4e-184 lacR K Transcriptional regulator
NECCCLDA_02010 2.3e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
NECCCLDA_02011 6.5e-232 malC P COG1175 ABC-type sugar transport systems, permease components
NECCCLDA_02012 7.2e-150 ganQ P transport
NECCCLDA_02013 0.0 lacA 3.2.1.23 G beta-galactosidase
NECCCLDA_02014 9.8e-252 galA 3.2.1.89 G arabinogalactan
NECCCLDA_02015 1.2e-198 rsbU 3.1.3.3 T response regulator
NECCCLDA_02016 3.7e-156 rsbQ S Alpha/beta hydrolase family
NECCCLDA_02018 7.1e-156 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NECCCLDA_02019 4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
NECCCLDA_02020 1.1e-193 desK 2.7.13.3 T Histidine kinase
NECCCLDA_02021 2.2e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NECCCLDA_02022 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NECCCLDA_02023 4.6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NECCCLDA_02024 7.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NECCCLDA_02025 4.9e-193 yvbX S Glycosyl hydrolase
NECCCLDA_02026 3.7e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NECCCLDA_02027 1.6e-155 yvbV EG EamA-like transporter family
NECCCLDA_02028 5.1e-159 yvbU K Transcriptional regulator
NECCCLDA_02029 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NECCCLDA_02030 5.5e-203 araR K transcriptional
NECCCLDA_02031 1.6e-252 araE EGP Major facilitator Superfamily
NECCCLDA_02032 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NECCCLDA_02033 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NECCCLDA_02034 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NECCCLDA_02035 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NECCCLDA_02036 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NECCCLDA_02037 1.9e-242 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NECCCLDA_02038 8.3e-76 yvbK 3.1.3.25 K acetyltransferase
NECCCLDA_02039 6.8e-251 tcaA S response to antibiotic
NECCCLDA_02040 1.2e-121 exoY M Membrane
NECCCLDA_02041 1.9e-112 yvbH S YvbH-like oligomerisation region
NECCCLDA_02042 2.8e-90 yvbG U UPF0056 membrane protein
NECCCLDA_02043 3.5e-97 yvbF K Belongs to the GbsR family
NECCCLDA_02044 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NECCCLDA_02045 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NECCCLDA_02046 6.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NECCCLDA_02047 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NECCCLDA_02048 2.1e-62 yvbF K Belongs to the GbsR family
NECCCLDA_02049 1.2e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NECCCLDA_02050 3.6e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NECCCLDA_02051 4.7e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NECCCLDA_02052 4.7e-104 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NECCCLDA_02053 1.3e-196 spaB S Lantibiotic dehydratase, C terminus
NECCCLDA_02054 1.7e-156 spaT V ABC transporter
NECCCLDA_02055 9.3e-96 spaC2 V PFAM Lanthionine synthetase
NECCCLDA_02056 1.1e-09 S Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
NECCCLDA_02058 4.2e-103 mutF V ABC transporter, ATP-binding protein
NECCCLDA_02059 1.5e-87 spaE S ABC-2 family transporter protein
NECCCLDA_02060 1.7e-81 mutG S ABC-2 family transporter protein
NECCCLDA_02061 2.5e-105 K Transcriptional regulatory protein, C terminal
NECCCLDA_02062 1.1e-152 T His Kinase A (phosphoacceptor) domain
NECCCLDA_02063 3.2e-218 NT chemotaxis protein
NECCCLDA_02064 2.2e-54 yodB K transcriptional
NECCCLDA_02065 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
NECCCLDA_02066 1.2e-68 K transcriptional
NECCCLDA_02067 9.8e-36 yvzC K Transcriptional
NECCCLDA_02068 8.2e-153 yvaM S Serine aminopeptidase, S33
NECCCLDA_02069 2.4e-23 secG U Preprotein translocase subunit SecG
NECCCLDA_02070 5.6e-143 est 3.1.1.1 S Carboxylesterase
NECCCLDA_02071 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NECCCLDA_02072 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NECCCLDA_02075 1.8e-15
NECCCLDA_02076 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NECCCLDA_02077 3.3e-98 K Bacterial regulatory proteins, tetR family
NECCCLDA_02078 3.4e-53 yvaE P Small Multidrug Resistance protein
NECCCLDA_02079 2.8e-72 yvaD S Family of unknown function (DUF5360)
NECCCLDA_02080 0.0 yvaC S Fusaric acid resistance protein-like
NECCCLDA_02081 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NECCCLDA_02082 6.9e-195 yvaA 1.1.1.371 S Oxidoreductase
NECCCLDA_02083 2.2e-48 csoR S transcriptional
NECCCLDA_02084 5.9e-29 copZ P Copper resistance protein CopZ
NECCCLDA_02085 0.0 copA 3.6.3.54 P P-type ATPase
NECCCLDA_02086 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NECCCLDA_02087 1.6e-104 bdbD O Thioredoxin
NECCCLDA_02088 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
NECCCLDA_02089 1.6e-106 yvgT S membrane
NECCCLDA_02091 0.0 helD 3.6.4.12 L DNA helicase
NECCCLDA_02092 2.9e-50 helD 3.6.4.12 L DNA helicase
NECCCLDA_02093 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NECCCLDA_02094 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NECCCLDA_02095 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NECCCLDA_02096 5.4e-86 yvgO
NECCCLDA_02097 1.1e-155 yvgN S reductase
NECCCLDA_02098 1.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
NECCCLDA_02099 1.7e-134 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NECCCLDA_02100 5.4e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NECCCLDA_02101 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NECCCLDA_02102 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NECCCLDA_02103 6.5e-16 S Small spore protein J (Spore_SspJ)
NECCCLDA_02104 4.9e-236 yvsH E Arginine ornithine antiporter
NECCCLDA_02106 6.9e-178 fhuD P ABC transporter
NECCCLDA_02107 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECCCLDA_02108 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECCCLDA_02109 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
NECCCLDA_02110 3.4e-174 M Efflux transporter rnd family, mfp subunit
NECCCLDA_02111 7.9e-123 macB V ABC transporter, ATP-binding protein
NECCCLDA_02112 8.9e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NECCCLDA_02113 1.3e-64 yvrL S Regulatory protein YrvL
NECCCLDA_02114 3.1e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
NECCCLDA_02115 2.4e-19 S YvrJ protein family
NECCCLDA_02116 1.9e-98 yvrI K RNA polymerase
NECCCLDA_02117 7.2e-23
NECCCLDA_02118 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECCCLDA_02119 0.0 T PhoQ Sensor
NECCCLDA_02120 4.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
NECCCLDA_02121 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NECCCLDA_02122 2.2e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NECCCLDA_02123 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECCCLDA_02124 9.5e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NECCCLDA_02125 1.3e-99 yvqK 2.5.1.17 S Adenosyltransferase
NECCCLDA_02126 2.4e-226 yvqJ EGP Major facilitator Superfamily
NECCCLDA_02127 5.6e-62 liaI S membrane
NECCCLDA_02128 9.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NECCCLDA_02129 6e-128 liaG S Putative adhesin
NECCCLDA_02130 2.8e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NECCCLDA_02131 2.7e-186 vraS 2.7.13.3 T Histidine kinase
NECCCLDA_02132 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NECCCLDA_02133 4.2e-182 gerAC S Spore germination B3/ GerAC like, C-terminal
NECCCLDA_02134 3.8e-196 gerAB E Spore germination protein
NECCCLDA_02135 1.2e-245 gerAA EG Spore germination protein
NECCCLDA_02136 3.9e-24 S Protein of unknown function (DUF3970)
NECCCLDA_02137 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NECCCLDA_02138 4.3e-158 yuxN K Transcriptional regulator
NECCCLDA_02139 1.7e-249 cssS 2.7.13.3 T PhoQ Sensor
NECCCLDA_02140 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECCCLDA_02141 1.2e-231 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NECCCLDA_02142 1.2e-79 dps P Ferritin-like domain
NECCCLDA_02143 4.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NECCCLDA_02144 1.2e-300 pepF2 E COG1164 Oligoendopeptidase F
NECCCLDA_02145 1.9e-66 S YusW-like protein
NECCCLDA_02146 1e-153 yusV 3.6.3.34 HP ABC transporter
NECCCLDA_02147 5.6e-39 yusU S Protein of unknown function (DUF2573)
NECCCLDA_02148 1.3e-157 yusT K LysR substrate binding domain
NECCCLDA_02149 5e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NECCCLDA_02150 2.7e-64 yusQ S Tautomerase enzyme
NECCCLDA_02151 1e-290 yusP P Major facilitator superfamily
NECCCLDA_02152 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
NECCCLDA_02153 5.4e-53 yusN M Coat F domain
NECCCLDA_02154 5.1e-40
NECCCLDA_02155 1.3e-162 fadM E Proline dehydrogenase
NECCCLDA_02156 8.1e-09 S YuzL-like protein
NECCCLDA_02157 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NECCCLDA_02158 2.7e-216 fadA 2.3.1.16 I Belongs to the thiolase family
NECCCLDA_02159 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NECCCLDA_02160 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NECCCLDA_02161 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NECCCLDA_02162 1.1e-39 yusG S Protein of unknown function (DUF2553)
NECCCLDA_02163 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NECCCLDA_02164 9.5e-55 traF CO Thioredoxin
NECCCLDA_02165 2.4e-56 yusD S SCP-2 sterol transfer family
NECCCLDA_02166 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NECCCLDA_02167 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NECCCLDA_02168 9.4e-147 metQ P Belongs to the NlpA lipoprotein family
NECCCLDA_02169 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NECCCLDA_02170 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NECCCLDA_02171 4.5e-244 sufD O assembly protein SufD
NECCCLDA_02172 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NECCCLDA_02173 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NECCCLDA_02174 3.5e-271 sufB O FeS cluster assembly
NECCCLDA_02175 7.1e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NECCCLDA_02176 1e-41
NECCCLDA_02178 1.1e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NECCCLDA_02179 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NECCCLDA_02180 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NECCCLDA_02181 8e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NECCCLDA_02182 1.2e-155 yurN G Binding-protein-dependent transport system inner membrane component
NECCCLDA_02183 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
NECCCLDA_02184 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NECCCLDA_02185 3.3e-135 yurK K UTRA
NECCCLDA_02186 5.9e-205 msmX P Belongs to the ABC transporter superfamily
NECCCLDA_02187 3.5e-168 bsn L Ribonuclease
NECCCLDA_02188 2.2e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NECCCLDA_02189 4.6e-238 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NECCCLDA_02190 1.2e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NECCCLDA_02191 5.3e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NECCCLDA_02192 5e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NECCCLDA_02193 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NECCCLDA_02194 6.9e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NECCCLDA_02196 1.7e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NECCCLDA_02197 1.9e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NECCCLDA_02198 3.3e-223 pbuX F xanthine
NECCCLDA_02199 1.1e-232 pbuX F Permease family
NECCCLDA_02200 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
NECCCLDA_02201 1.9e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NECCCLDA_02202 8.2e-60 yunG
NECCCLDA_02203 7.3e-171 yunF S Protein of unknown function DUF72
NECCCLDA_02204 2e-141 yunE S membrane transporter protein
NECCCLDA_02205 1.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NECCCLDA_02206 1.1e-47 yunC S Domain of unknown function (DUF1805)
NECCCLDA_02207 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
NECCCLDA_02208 1.3e-195 lytH M Peptidase, M23
NECCCLDA_02209 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NECCCLDA_02210 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NECCCLDA_02211 9.7e-48 yutD S protein conserved in bacteria
NECCCLDA_02212 1e-75 yutE S Protein of unknown function DUF86
NECCCLDA_02213 4.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NECCCLDA_02214 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NECCCLDA_02215 6.5e-198 yutH S Spore coat protein
NECCCLDA_02216 7.9e-241 hom 1.1.1.3 E homoserine dehydrogenase
NECCCLDA_02217 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NECCCLDA_02218 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NECCCLDA_02219 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NECCCLDA_02220 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NECCCLDA_02221 5.1e-56 yuzD S protein conserved in bacteria
NECCCLDA_02222 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NECCCLDA_02223 3.2e-39 yuzB S Belongs to the UPF0349 family
NECCCLDA_02224 1.6e-198 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NECCCLDA_02225 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NECCCLDA_02226 3.7e-63 erpA S Belongs to the HesB IscA family
NECCCLDA_02227 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NECCCLDA_02228 3.8e-116 paiB K Putative FMN-binding domain
NECCCLDA_02229 5.1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NECCCLDA_02231 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
NECCCLDA_02232 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
NECCCLDA_02233 8.4e-27 yuiB S Putative membrane protein
NECCCLDA_02234 1.4e-116 yuiC S protein conserved in bacteria
NECCCLDA_02235 1.2e-77 yuiD S protein conserved in bacteria
NECCCLDA_02236 1.3e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NECCCLDA_02237 3.9e-211 yuiF S antiporter
NECCCLDA_02238 1.1e-93 bioY S Biotin biosynthesis protein
NECCCLDA_02239 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
NECCCLDA_02240 8e-165 besA S Putative esterase
NECCCLDA_02241 1.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NECCCLDA_02242 4.3e-225 entC 5.4.4.2 HQ Isochorismate synthase
NECCCLDA_02243 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NECCCLDA_02244 6.8e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NECCCLDA_02245 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NECCCLDA_02246 5e-36 mbtH S MbtH-like protein
NECCCLDA_02247 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NECCCLDA_02248 1.5e-203 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NECCCLDA_02249 4.7e-227 yukF QT Transcriptional regulator
NECCCLDA_02250 2.8e-45 esxA S Belongs to the WXG100 family
NECCCLDA_02251 1.7e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
NECCCLDA_02252 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
NECCCLDA_02253 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NECCCLDA_02254 0.0 esaA S type VII secretion protein EsaA
NECCCLDA_02255 2.5e-64 yueC S Family of unknown function (DUF5383)
NECCCLDA_02256 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECCCLDA_02257 1.8e-95 yueE S phosphohydrolase
NECCCLDA_02258 2.9e-24 S Protein of unknown function (DUF2642)
NECCCLDA_02259 5.2e-71 S Protein of unknown function (DUF2283)
NECCCLDA_02260 3.2e-190 yueF S transporter activity
NECCCLDA_02261 6.6e-31 yueG S Spore germination protein gerPA/gerPF
NECCCLDA_02262 7.4e-39 yueH S YueH-like protein
NECCCLDA_02263 5.1e-66 yueI S Protein of unknown function (DUF1694)
NECCCLDA_02264 1.2e-102 pncA Q COG1335 Amidases related to nicotinamidase
NECCCLDA_02265 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NECCCLDA_02266 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NECCCLDA_02267 8.5e-23 yuzC
NECCCLDA_02269 2.9e-128 comQ H Belongs to the FPP GGPP synthase family
NECCCLDA_02271 0.0 comP 2.7.13.3 T Histidine kinase
NECCCLDA_02272 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NECCCLDA_02273 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
NECCCLDA_02274 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NECCCLDA_02275 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NECCCLDA_02276 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NECCCLDA_02277 4.2e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NECCCLDA_02278 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NECCCLDA_02279 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NECCCLDA_02280 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NECCCLDA_02281 5e-15
NECCCLDA_02282 8.2e-233 maeN C COG3493 Na citrate symporter
NECCCLDA_02283 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
NECCCLDA_02284 2.1e-183 yufP S Belongs to the binding-protein-dependent transport system permease family
NECCCLDA_02285 1.9e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NECCCLDA_02286 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NECCCLDA_02287 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
NECCCLDA_02288 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NECCCLDA_02289 6.3e-78 yufK S Family of unknown function (DUF5366)
NECCCLDA_02290 9.1e-74 yuxK S protein conserved in bacteria
NECCCLDA_02291 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NECCCLDA_02292 4.2e-184 yuxJ EGP Major facilitator Superfamily
NECCCLDA_02294 4.2e-115 kapD L the KinA pathway to sporulation
NECCCLDA_02295 7.4e-70 kapB G Kinase associated protein B
NECCCLDA_02296 1.3e-232 T PhoQ Sensor
NECCCLDA_02297 7.6e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NECCCLDA_02298 1.1e-40 yugE S Domain of unknown function (DUF1871)
NECCCLDA_02299 4.2e-155 yugF I Hydrolase
NECCCLDA_02300 1.6e-85 alaR K Transcriptional regulator
NECCCLDA_02301 2.1e-199 yugH 2.6.1.1 E Aminotransferase
NECCCLDA_02302 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NECCCLDA_02303 1.1e-34 yuzA S Domain of unknown function (DUF378)
NECCCLDA_02304 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NECCCLDA_02305 1.1e-228 yugK C Dehydrogenase
NECCCLDA_02306 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NECCCLDA_02308 1.3e-72 yugN S YugN-like family
NECCCLDA_02309 1.7e-182 yugO P COG1226 Kef-type K transport systems
NECCCLDA_02310 1.1e-53 mstX S Membrane-integrating protein Mistic
NECCCLDA_02311 4.6e-39
NECCCLDA_02312 1.4e-116 yugP S Zn-dependent protease
NECCCLDA_02313 1.3e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NECCCLDA_02314 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NECCCLDA_02315 2.1e-72 yugU S Uncharacterised protein family UPF0047
NECCCLDA_02316 2.3e-35
NECCCLDA_02317 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NECCCLDA_02318 3.2e-225 mcpA NT chemotaxis protein
NECCCLDA_02319 1.5e-222 mcpA NT chemotaxis protein
NECCCLDA_02320 1.6e-293 mcpA NT chemotaxis protein
NECCCLDA_02321 5.1e-239 mcpA NT chemotaxis protein
NECCCLDA_02322 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NECCCLDA_02323 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NECCCLDA_02324 3.3e-280 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NECCCLDA_02325 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NECCCLDA_02326 4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NECCCLDA_02327 9.7e-183 ygjR S Oxidoreductase
NECCCLDA_02328 9.1e-196 yubA S transporter activity
NECCCLDA_02329 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NECCCLDA_02331 1.3e-84 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NECCCLDA_02332 1e-271 yubD P Major Facilitator Superfamily
NECCCLDA_02333 5.4e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NECCCLDA_02334 1e-38 yiaA S yiaA/B two helix domain
NECCCLDA_02335 2.7e-236 ktrB P Potassium
NECCCLDA_02336 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
NECCCLDA_02337 2.2e-91 yuaB
NECCCLDA_02338 3.6e-94 yuaC K Belongs to the GbsR family
NECCCLDA_02339 4e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NECCCLDA_02340 3.2e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
NECCCLDA_02341 1.1e-106 yuaD
NECCCLDA_02342 3.9e-84 yuaE S DinB superfamily
NECCCLDA_02343 1.9e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NECCCLDA_02344 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
NECCCLDA_02345 5.5e-92 M1-753 M FR47-like protein
NECCCLDA_02346 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
NECCCLDA_02347 4.8e-63 mftE 3.5.2.10 S creatinine amidohydrolase family protein
NECCCLDA_02352 7.8e-08
NECCCLDA_02360 2e-08
NECCCLDA_02364 5e-142 spo0M S COG4326 Sporulation control protein
NECCCLDA_02365 1.2e-26
NECCCLDA_02366 4.8e-128 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NECCCLDA_02367 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NECCCLDA_02369 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NECCCLDA_02370 8.7e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NECCCLDA_02371 6.2e-169 ssuA M Sulfonate ABC transporter
NECCCLDA_02372 2.7e-146 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NECCCLDA_02373 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NECCCLDA_02375 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NECCCLDA_02376 5.5e-75 ygaO
NECCCLDA_02377 4.4e-29 K Transcriptional regulator
NECCCLDA_02379 8.7e-113 yhzB S B3/4 domain
NECCCLDA_02380 3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NECCCLDA_02381 3.7e-176 yhbB S Putative amidase domain
NECCCLDA_02382 1.8e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NECCCLDA_02383 1.2e-109 yhbD K Protein of unknown function (DUF4004)
NECCCLDA_02384 7.8e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NECCCLDA_02385 1.1e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NECCCLDA_02386 0.0 prkA T Ser protein kinase
NECCCLDA_02387 2.5e-225 yhbH S Belongs to the UPF0229 family
NECCCLDA_02388 2.2e-76 yhbI K DNA-binding transcription factor activity
NECCCLDA_02389 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NECCCLDA_02390 3.1e-271 yhcA EGP Major facilitator Superfamily
NECCCLDA_02391 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NECCCLDA_02392 2.8e-37 yhcC
NECCCLDA_02393 3.5e-55
NECCCLDA_02394 6.6e-60 yhcF K Transcriptional regulator
NECCCLDA_02395 4e-122 yhcG V ABC transporter, ATP-binding protein
NECCCLDA_02396 8.5e-165 yhcH V ABC transporter, ATP-binding protein
NECCCLDA_02397 1.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NECCCLDA_02398 1e-30 cspB K Cold-shock protein
NECCCLDA_02399 1.1e-150 metQ M Belongs to the nlpA lipoprotein family
NECCCLDA_02400 4.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NECCCLDA_02401 4.1e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NECCCLDA_02402 8.3e-78 S Protein of unknown function (DUF2812)
NECCCLDA_02403 1.2e-49 K Transcriptional regulator PadR-like family
NECCCLDA_02404 4.1e-40 yhcM
NECCCLDA_02405 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NECCCLDA_02406 7.3e-167 yhcP
NECCCLDA_02407 1.5e-99 yhcQ M Spore coat protein
NECCCLDA_02408 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NECCCLDA_02409 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NECCCLDA_02410 1.9e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NECCCLDA_02411 9.3e-68 yhcU S Family of unknown function (DUF5365)
NECCCLDA_02412 9.9e-68 yhcV S COG0517 FOG CBS domain
NECCCLDA_02413 1.3e-119 yhcW 5.4.2.6 S hydrolase
NECCCLDA_02414 1.7e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NECCCLDA_02415 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NECCCLDA_02416 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NECCCLDA_02417 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NECCCLDA_02418 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NECCCLDA_02419 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NECCCLDA_02420 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NECCCLDA_02421 2.6e-211 yhcY 2.7.13.3 T Histidine kinase
NECCCLDA_02422 7.2e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NECCCLDA_02423 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
NECCCLDA_02424 1.2e-38 yhdB S YhdB-like protein
NECCCLDA_02425 1.8e-53 yhdC S Protein of unknown function (DUF3889)
NECCCLDA_02426 2.3e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NECCCLDA_02427 6e-76 nsrR K Transcriptional regulator
NECCCLDA_02428 1.3e-237 ygxB M Conserved TM helix
NECCCLDA_02429 6.3e-276 ycgB S Stage V sporulation protein R
NECCCLDA_02430 4.9e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NECCCLDA_02431 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NECCCLDA_02432 3.8e-162 citR K Transcriptional regulator
NECCCLDA_02433 2.5e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
NECCCLDA_02434 1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECCCLDA_02435 1.7e-249 yhdG E amino acid
NECCCLDA_02436 3.7e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NECCCLDA_02437 7.4e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECCCLDA_02438 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NECCCLDA_02439 8.1e-45 yhdK S Sigma-M inhibitor protein
NECCCLDA_02440 3.3e-200 yhdL S Sigma factor regulator N-terminal
NECCCLDA_02441 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NECCCLDA_02442 1.5e-191 yhdN C Aldo keto reductase
NECCCLDA_02443 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NECCCLDA_02444 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NECCCLDA_02445 4.1e-74 cueR K transcriptional
NECCCLDA_02446 8.8e-223 yhdR 2.6.1.1 E Aminotransferase
NECCCLDA_02447 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NECCCLDA_02448 3.2e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NECCCLDA_02449 2.1e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NECCCLDA_02450 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NECCCLDA_02452 9.9e-184 yhdY M Mechanosensitive ion channel
NECCCLDA_02453 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NECCCLDA_02454 4.8e-146 yheN G deacetylase
NECCCLDA_02455 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NECCCLDA_02456 3.3e-229 nhaC C Na H antiporter
NECCCLDA_02457 1.5e-83 nhaX T Belongs to the universal stress protein A family
NECCCLDA_02458 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NECCCLDA_02459 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NECCCLDA_02460 4.5e-109 yheG GM NAD(P)H-binding
NECCCLDA_02461 6.3e-28 sspB S spore protein
NECCCLDA_02462 1.3e-36 yheE S Family of unknown function (DUF5342)
NECCCLDA_02463 2.2e-265 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NECCCLDA_02464 1.6e-215 yheC HJ YheC/D like ATP-grasp
NECCCLDA_02465 6.3e-202 yheB S Belongs to the UPF0754 family
NECCCLDA_02466 9.5e-48 yheA S Belongs to the UPF0342 family
NECCCLDA_02467 7.5e-205 yhaZ L DNA alkylation repair enzyme
NECCCLDA_02468 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NECCCLDA_02469 3e-292 hemZ H coproporphyrinogen III oxidase
NECCCLDA_02470 4.8e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NECCCLDA_02471 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NECCCLDA_02473 6.7e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
NECCCLDA_02474 7e-26 S YhzD-like protein
NECCCLDA_02475 5.2e-167 yhaQ S ABC transporter, ATP-binding protein
NECCCLDA_02476 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NECCCLDA_02477 2.6e-225 yhaO L DNA repair exonuclease
NECCCLDA_02478 0.0 yhaN L AAA domain
NECCCLDA_02479 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NECCCLDA_02480 1.6e-21 yhaL S Sporulation protein YhaL
NECCCLDA_02481 2e-115 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NECCCLDA_02482 8.7e-90 yhaK S Putative zincin peptidase
NECCCLDA_02483 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NECCCLDA_02484 1e-113 hpr K Negative regulator of protease production and sporulation
NECCCLDA_02485 8.2e-39 yhaH S YtxH-like protein
NECCCLDA_02486 5.4e-21
NECCCLDA_02487 3.6e-80 trpP S Tryptophan transporter TrpP
NECCCLDA_02488 1.9e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NECCCLDA_02489 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NECCCLDA_02490 4.6e-137 ecsA V transporter (ATP-binding protein)
NECCCLDA_02491 5.4e-215 ecsB U ABC transporter
NECCCLDA_02492 4.5e-113 ecsC S EcsC protein family
NECCCLDA_02493 1.1e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NECCCLDA_02494 1.9e-240 yhfA C membrane
NECCCLDA_02495 4.1e-28 1.15.1.2 C Rubrerythrin
NECCCLDA_02496 6.4e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NECCCLDA_02497 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NECCCLDA_02498 4.5e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NECCCLDA_02499 8.9e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NECCCLDA_02500 2.2e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NECCCLDA_02501 5.4e-101 yhgD K Transcriptional regulator
NECCCLDA_02502 1.1e-213 yhgE S YhgE Pip N-terminal domain protein
NECCCLDA_02503 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NECCCLDA_02504 1.7e-134 yhfC S Putative membrane peptidase family (DUF2324)
NECCCLDA_02505 5.1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NECCCLDA_02506 3.7e-72 3.4.13.21 S ASCH
NECCCLDA_02507 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NECCCLDA_02508 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NECCCLDA_02509 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
NECCCLDA_02510 1.2e-109 yhfK GM NmrA-like family
NECCCLDA_02511 5e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NECCCLDA_02512 1.9e-65 yhfM
NECCCLDA_02513 6.9e-237 yhfN 3.4.24.84 O Peptidase M48
NECCCLDA_02514 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NECCCLDA_02515 1.1e-77 VY92_01935 K acetyltransferase
NECCCLDA_02516 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
NECCCLDA_02517 2.8e-158 yfmC M Periplasmic binding protein
NECCCLDA_02518 3e-107 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NECCCLDA_02519 4.4e-200 vraB 2.3.1.9 I Belongs to the thiolase family
NECCCLDA_02520 1.5e-277 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NECCCLDA_02521 5e-91 bioY S BioY family
NECCCLDA_02522 1.7e-182 hemAT NT chemotaxis protein
NECCCLDA_02523 5.7e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NECCCLDA_02524 4.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECCCLDA_02525 1.3e-32 yhzC S IDEAL
NECCCLDA_02526 9.3e-109 comK K Competence transcription factor
NECCCLDA_02527 6.2e-168 IQ Enoyl-(Acyl carrier protein) reductase
NECCCLDA_02528 1.2e-39 yhjA S Excalibur calcium-binding domain
NECCCLDA_02529 5.7e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NECCCLDA_02530 6.9e-27 yhjC S Protein of unknown function (DUF3311)
NECCCLDA_02531 6.7e-60 yhjD
NECCCLDA_02532 9.1e-110 yhjE S SNARE associated Golgi protein
NECCCLDA_02533 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NECCCLDA_02534 5.2e-281 yhjG CH FAD binding domain
NECCCLDA_02535 2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
NECCCLDA_02538 2.9e-213 glcP G Major Facilitator Superfamily
NECCCLDA_02539 7.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NECCCLDA_02540 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NECCCLDA_02541 1.2e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NECCCLDA_02542 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
NECCCLDA_02543 4.2e-201 abrB S membrane
NECCCLDA_02544 7.4e-209 EGP Transmembrane secretion effector
NECCCLDA_02545 0.0 S Sugar transport-related sRNA regulator N-term
NECCCLDA_02546 2e-36 yhjQ C COG1145 Ferredoxin
NECCCLDA_02547 4.9e-78 yhjR S Rubrerythrin
NECCCLDA_02548 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NECCCLDA_02549 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NECCCLDA_02550 1.8e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NECCCLDA_02551 0.0 sbcC L COG0419 ATPase involved in DNA repair
NECCCLDA_02552 1.1e-49 yisB V COG1403 Restriction endonuclease
NECCCLDA_02553 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NECCCLDA_02554 5.3e-63 gerPE S Spore germination protein GerPE
NECCCLDA_02555 1.1e-23 gerPD S Spore germination protein
NECCCLDA_02556 5.3e-54 gerPC S Spore germination protein
NECCCLDA_02557 4e-34 gerPB S cell differentiation
NECCCLDA_02558 1.9e-33 gerPA S Spore germination protein
NECCCLDA_02559 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NECCCLDA_02560 2.7e-174 cotH M Spore Coat
NECCCLDA_02561 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NECCCLDA_02562 3e-57 yisL S UPF0344 protein
NECCCLDA_02563 0.0 wprA O Belongs to the peptidase S8 family
NECCCLDA_02564 1.5e-100 yisN S Protein of unknown function (DUF2777)
NECCCLDA_02565 0.0 asnO 6.3.5.4 E Asparagine synthase
NECCCLDA_02566 4.7e-88 yizA S Damage-inducible protein DinB
NECCCLDA_02567 4.1e-147 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NECCCLDA_02568 1.5e-242 yisQ V Mate efflux family protein
NECCCLDA_02569 1.2e-160 yisR K Transcriptional regulator
NECCCLDA_02570 2.4e-184 purR K helix_turn _helix lactose operon repressor
NECCCLDA_02571 6.3e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NECCCLDA_02572 1.5e-91 yisT S DinB family
NECCCLDA_02573 2e-106 argO S Lysine exporter protein LysE YggA
NECCCLDA_02574 1.2e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECCCLDA_02575 4e-36 mcbG S Pentapeptide repeats (9 copies)
NECCCLDA_02576 1e-153 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NECCCLDA_02577 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NECCCLDA_02578 1.3e-229 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NECCCLDA_02579 5.1e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NECCCLDA_02580 2e-118 comB 3.1.3.71 H Belongs to the ComB family
NECCCLDA_02581 1.6e-140 yitD 4.4.1.19 S synthase
NECCCLDA_02582 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NECCCLDA_02583 6e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NECCCLDA_02584 2e-228 yitG EGP Major facilitator Superfamily
NECCCLDA_02585 1.8e-153 yitH K Acetyltransferase (GNAT) domain
NECCCLDA_02586 1e-70 yjcF S Acetyltransferase (GNAT) domain
NECCCLDA_02587 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NECCCLDA_02588 4.3e-54 yajQ S Belongs to the UPF0234 family
NECCCLDA_02589 6.9e-161 cvfB S protein conserved in bacteria
NECCCLDA_02590 8.5e-94
NECCCLDA_02591 4.7e-171
NECCCLDA_02592 1.5e-97 S Sporulation delaying protein SdpA
NECCCLDA_02593 1.5e-58 K Transcriptional regulator PadR-like family
NECCCLDA_02594 1.6e-92
NECCCLDA_02595 1.4e-44 yitR S Domain of unknown function (DUF3784)
NECCCLDA_02596 1.3e-309 nprB 3.4.24.28 E Peptidase M4
NECCCLDA_02597 1.4e-158 yitS S protein conserved in bacteria
NECCCLDA_02598 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NECCCLDA_02599 1.2e-71 ipi S Intracellular proteinase inhibitor
NECCCLDA_02600 1.2e-17 S Protein of unknown function (DUF3813)
NECCCLDA_02601 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NECCCLDA_02602 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NECCCLDA_02603 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NECCCLDA_02604 1.5e-22 pilT S Proteolipid membrane potential modulator
NECCCLDA_02605 3.4e-269 yitY C D-arabinono-1,4-lactone oxidase
NECCCLDA_02606 1.7e-88 norB G Major Facilitator Superfamily
NECCCLDA_02607 1.1e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NECCCLDA_02608 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NECCCLDA_02609 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NECCCLDA_02610 4.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NECCCLDA_02611 1.1e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NECCCLDA_02612 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NECCCLDA_02613 4.2e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NECCCLDA_02614 9.5e-28 yjzC S YjzC-like protein
NECCCLDA_02615 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NECCCLDA_02616 5.2e-141 yjaU I carboxylic ester hydrolase activity
NECCCLDA_02617 5.8e-100 yjaV
NECCCLDA_02618 2.5e-183 med S Transcriptional activator protein med
NECCCLDA_02619 1.6e-25 comZ S ComZ
NECCCLDA_02620 1.1e-20 yjzB
NECCCLDA_02621 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NECCCLDA_02622 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NECCCLDA_02623 2.5e-149 yjaZ O Zn-dependent protease
NECCCLDA_02624 1.8e-184 appD P Belongs to the ABC transporter superfamily
NECCCLDA_02625 1.4e-184 appF E Belongs to the ABC transporter superfamily
NECCCLDA_02626 7e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NECCCLDA_02627 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NECCCLDA_02628 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NECCCLDA_02629 5e-147 yjbA S Belongs to the UPF0736 family
NECCCLDA_02630 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NECCCLDA_02631 0.0 oppA E ABC transporter substrate-binding protein
NECCCLDA_02632 8.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NECCCLDA_02633 1.9e-164 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NECCCLDA_02634 3e-198 oppD P Belongs to the ABC transporter superfamily
NECCCLDA_02635 1.2e-171 oppF E Belongs to the ABC transporter superfamily
NECCCLDA_02636 6.3e-205 yjbB EGP Major Facilitator Superfamily
NECCCLDA_02637 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NECCCLDA_02638 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NECCCLDA_02639 6e-112 yjbE P Integral membrane protein TerC family
NECCCLDA_02640 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NECCCLDA_02641 6.4e-218 yjbF S Competence protein
NECCCLDA_02642 0.0 pepF E oligoendopeptidase F
NECCCLDA_02643 1.8e-20
NECCCLDA_02645 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NECCCLDA_02646 3.7e-72 yjbI S Bacterial-like globin
NECCCLDA_02647 1e-99 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NECCCLDA_02648 4.1e-101 yjbK S protein conserved in bacteria
NECCCLDA_02649 2.1e-61 yjbL S Belongs to the UPF0738 family
NECCCLDA_02650 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NECCCLDA_02651 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NECCCLDA_02652 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NECCCLDA_02653 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NECCCLDA_02654 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NECCCLDA_02655 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NECCCLDA_02656 1.6e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NECCCLDA_02657 1.4e-217 thiO 1.4.3.19 E Glycine oxidase
NECCCLDA_02658 6.7e-30 thiS H thiamine diphosphate biosynthetic process
NECCCLDA_02659 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NECCCLDA_02660 2.3e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NECCCLDA_02661 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NECCCLDA_02662 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NECCCLDA_02663 1.9e-52 yjbX S Spore coat protein
NECCCLDA_02664 5.2e-83 cotZ S Spore coat protein
NECCCLDA_02665 3.4e-96 cotY S Spore coat protein Z
NECCCLDA_02666 4e-71 cotX S Spore Coat Protein X and V domain
NECCCLDA_02667 9.9e-23 cotW
NECCCLDA_02668 3e-55 cotV S Spore Coat Protein X and V domain
NECCCLDA_02669 5.6e-56 yjcA S Protein of unknown function (DUF1360)
NECCCLDA_02672 2.9e-38 spoVIF S Stage VI sporulation protein F
NECCCLDA_02673 0.0 yjcD 3.6.4.12 L DNA helicase
NECCCLDA_02674 1.7e-38
NECCCLDA_02675 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NECCCLDA_02676 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NECCCLDA_02677 5.3e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
NECCCLDA_02678 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NECCCLDA_02679 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NECCCLDA_02680 1.2e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
NECCCLDA_02681 2.4e-212 yjcL S Protein of unknown function (DUF819)
NECCCLDA_02684 1.6e-38
NECCCLDA_02685 1e-29
NECCCLDA_02688 1.4e-22 S response regulator aspartate phosphatase
NECCCLDA_02689 6e-137 S response regulator aspartate phosphatase
NECCCLDA_02690 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
NECCCLDA_02691 2.3e-45 yjcN
NECCCLDA_02692 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NECCCLDA_02693 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NECCCLDA_02694 1.5e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
NECCCLDA_02695 2.2e-48 yjdF S Protein of unknown function (DUF2992)
NECCCLDA_02696 2e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NECCCLDA_02698 5.2e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NECCCLDA_02699 4.6e-28 S Domain of unknown function (DUF4177)
NECCCLDA_02700 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
NECCCLDA_02701 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NECCCLDA_02703 4.6e-263 xynD 3.5.1.104 G Polysaccharide deacetylase
NECCCLDA_02704 5.5e-83 S Protein of unknown function (DUF2690)
NECCCLDA_02705 2.3e-20 yjfB S Putative motility protein
NECCCLDA_02706 6.8e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
NECCCLDA_02707 1.2e-45 T PhoQ Sensor
NECCCLDA_02708 2e-103 yjgB S Domain of unknown function (DUF4309)
NECCCLDA_02709 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NECCCLDA_02710 4.3e-95 yjgD S Protein of unknown function (DUF1641)
NECCCLDA_02712 6.6e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NECCCLDA_02714 8.9e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NECCCLDA_02715 1.6e-216 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NECCCLDA_02716 3.4e-99 dam2 2.1.1.72 L DNA methyltransferase
NECCCLDA_02717 6e-74 S AAA ATPase domain
NECCCLDA_02718 8.2e-30
NECCCLDA_02719 1.2e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NECCCLDA_02720 1.9e-122 ybbM S transport system, permease component
NECCCLDA_02721 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NECCCLDA_02722 1.1e-175 yjlA EG Putative multidrug resistance efflux transporter
NECCCLDA_02723 7.5e-91 yjlB S Cupin domain
NECCCLDA_02724 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NECCCLDA_02725 7.7e-219 yjlD 1.6.99.3 C NADH dehydrogenase
NECCCLDA_02726 4.6e-279 uxaC 5.3.1.12 G glucuronate isomerase
NECCCLDA_02727 7.8e-247 yjmB G symporter YjmB
NECCCLDA_02728 2.1e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NECCCLDA_02729 3e-187 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NECCCLDA_02730 7.5e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NECCCLDA_02731 7.5e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NECCCLDA_02732 1.8e-226 exuT G Sugar (and other) transporter
NECCCLDA_02733 5.2e-184 exuR K transcriptional
NECCCLDA_02734 1.7e-281 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NECCCLDA_02735 1.1e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NECCCLDA_02736 7.4e-130 MA20_18170 S membrane transporter protein
NECCCLDA_02737 2.3e-78 yjoA S DinB family
NECCCLDA_02738 2.3e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NECCCLDA_02739 1e-212 S response regulator aspartate phosphatase
NECCCLDA_02741 6.3e-41 S YCII-related domain
NECCCLDA_02742 7.2e-167 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NECCCLDA_02743 2.3e-60 yjqA S Bacterial PH domain
NECCCLDA_02744 3.3e-109 yjqB S Pfam:DUF867
NECCCLDA_02745 4.4e-160 ydbD P Catalase
NECCCLDA_02746 1.6e-111 xkdA E IrrE N-terminal-like domain
NECCCLDA_02747 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
NECCCLDA_02749 1.7e-156 xkdB K sequence-specific DNA binding
NECCCLDA_02750 4.1e-118 xkdC L Bacterial dnaA protein
NECCCLDA_02753 2.3e-09 yqaO S Phage-like element PBSX protein XtrA
NECCCLDA_02754 7e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NECCCLDA_02755 1.5e-138 xtmA L phage terminase small subunit
NECCCLDA_02756 4.5e-252 xtmB S phage terminase, large subunit
NECCCLDA_02757 1.6e-285 yqbA S portal protein
NECCCLDA_02758 1e-132 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NECCCLDA_02759 5.8e-169 xkdG S Phage capsid family
NECCCLDA_02760 5.1e-63 yqbG S Protein of unknown function (DUF3199)
NECCCLDA_02761 2.5e-64 yqbH S Domain of unknown function (DUF3599)
NECCCLDA_02762 2.9e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
NECCCLDA_02763 1.9e-77 xkdJ
NECCCLDA_02764 2.5e-256 xkdK S Phage tail sheath C-terminal domain
NECCCLDA_02765 6.1e-76 xkdM S Phage tail tube protein
NECCCLDA_02766 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
NECCCLDA_02767 0.0 xkdO L Transglycosylase SLT domain
NECCCLDA_02768 9.9e-115 xkdP S Lysin motif
NECCCLDA_02769 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
NECCCLDA_02770 2.1e-39 xkdR S Protein of unknown function (DUF2577)
NECCCLDA_02771 4.1e-69 xkdS S Protein of unknown function (DUF2634)
NECCCLDA_02772 3.9e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NECCCLDA_02773 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NECCCLDA_02774 8.7e-41
NECCCLDA_02775 0.0
NECCCLDA_02776 1.5e-42 xkdW S XkdW protein
NECCCLDA_02777 2.1e-21 xkdX
NECCCLDA_02778 2.8e-154 xepA
NECCCLDA_02779 2.8e-39 xhlA S Haemolysin XhlA
NECCCLDA_02780 9.3e-40 xhlB S SPP1 phage holin
NECCCLDA_02781 1.3e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NECCCLDA_02782 6.7e-23 spoIISB S Stage II sporulation protein SB
NECCCLDA_02783 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NECCCLDA_02784 5.8e-175 pit P phosphate transporter
NECCCLDA_02785 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NECCCLDA_02786 6.1e-241 steT E amino acid
NECCCLDA_02787 6.1e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NECCCLDA_02789 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NECCCLDA_02790 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NECCCLDA_02791 2.2e-209 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NECCCLDA_02792 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NECCCLDA_02793 5.1e-153 dppA E D-aminopeptidase
NECCCLDA_02794 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NECCCLDA_02795 2.1e-174 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NECCCLDA_02796 5.6e-186 dppD P Belongs to the ABC transporter superfamily
NECCCLDA_02797 0.0 dppE E ABC transporter substrate-binding protein
NECCCLDA_02799 3.5e-174 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NECCCLDA_02800 1.8e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NECCCLDA_02801 5.3e-164 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NECCCLDA_02802 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
NECCCLDA_02803 6.9e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
NECCCLDA_02804 2e-160 ykgA E Amidinotransferase
NECCCLDA_02805 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NECCCLDA_02806 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NECCCLDA_02807 1e-10
NECCCLDA_02808 2.7e-129 ykjA S Protein of unknown function (DUF421)
NECCCLDA_02809 2e-97 ykkA S Protein of unknown function (DUF664)
NECCCLDA_02810 1.1e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NECCCLDA_02811 3.5e-55 ykkC P Multidrug resistance protein
NECCCLDA_02812 7e-50 ykkD P Multidrug resistance protein
NECCCLDA_02813 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NECCCLDA_02814 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NECCCLDA_02815 1.2e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NECCCLDA_02816 3.7e-70 ohrA O Organic hydroperoxide resistance protein
NECCCLDA_02817 4.4e-74 ohrR K COG1846 Transcriptional regulators
NECCCLDA_02818 8.4e-72 ohrB O Organic hydroperoxide resistance protein
NECCCLDA_02819 1.4e-86 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NECCCLDA_02820 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NECCCLDA_02821 1.7e-176 isp O Belongs to the peptidase S8 family
NECCCLDA_02822 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NECCCLDA_02823 5.3e-136 ykoC P Cobalt transport protein
NECCCLDA_02824 6.8e-306 P ABC transporter, ATP-binding protein
NECCCLDA_02825 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
NECCCLDA_02826 1.1e-109 ykoF S YKOF-related Family
NECCCLDA_02827 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECCCLDA_02828 2.2e-241 ykoH 2.7.13.3 T Histidine kinase
NECCCLDA_02829 1.8e-111 ykoI S Peptidase propeptide and YPEB domain
NECCCLDA_02830 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
NECCCLDA_02833 2.2e-222 mgtE P Acts as a magnesium transporter
NECCCLDA_02834 1.4e-53 tnrA K transcriptional
NECCCLDA_02835 5.9e-18
NECCCLDA_02836 6.9e-26 ykoL
NECCCLDA_02837 1.3e-81 mhqR K transcriptional
NECCCLDA_02838 5.2e-189 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NECCCLDA_02839 1.9e-97 ykoP G polysaccharide deacetylase
NECCCLDA_02840 6.6e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NECCCLDA_02841 0.0 ykoS
NECCCLDA_02842 4.8e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NECCCLDA_02843 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NECCCLDA_02844 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NECCCLDA_02845 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
NECCCLDA_02846 2.7e-109 ykoX S membrane-associated protein
NECCCLDA_02847 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NECCCLDA_02848 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NECCCLDA_02849 7.7e-107 rsgI S Anti-sigma factor N-terminus
NECCCLDA_02850 1.9e-26 sspD S small acid-soluble spore protein
NECCCLDA_02851 3.3e-124 ykrK S Domain of unknown function (DUF1836)
NECCCLDA_02852 3.5e-155 htpX O Belongs to the peptidase M48B family
NECCCLDA_02853 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
NECCCLDA_02854 1.2e-10 ydfR S Protein of unknown function (DUF421)
NECCCLDA_02855 4.1e-18 ykzE
NECCCLDA_02856 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NECCCLDA_02857 0.0 kinE 2.7.13.3 T Histidine kinase
NECCCLDA_02858 1.6e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NECCCLDA_02860 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NECCCLDA_02861 1.3e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NECCCLDA_02862 3.8e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NECCCLDA_02863 2.9e-229 mtnE 2.6.1.83 E Aminotransferase
NECCCLDA_02864 3.4e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NECCCLDA_02865 2.4e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NECCCLDA_02866 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NECCCLDA_02867 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NECCCLDA_02868 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
NECCCLDA_02869 6.4e-09 S Spo0E like sporulation regulatory protein
NECCCLDA_02870 1.4e-64 eag
NECCCLDA_02871 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NECCCLDA_02872 5.1e-75 ykvE K transcriptional
NECCCLDA_02873 2.5e-125 motB N Flagellar motor protein
NECCCLDA_02874 2.7e-138 motA N flagellar motor
NECCCLDA_02875 0.0 clpE O Belongs to the ClpA ClpB family
NECCCLDA_02876 4e-179 ykvI S membrane
NECCCLDA_02877 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NECCCLDA_02878 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NECCCLDA_02879 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NECCCLDA_02880 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NECCCLDA_02881 2.4e-59 ykvN K HxlR-like helix-turn-helix
NECCCLDA_02882 2.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
NECCCLDA_02883 2.1e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
NECCCLDA_02884 3.5e-35 3.5.1.104 M LysM domain
NECCCLDA_02885 9e-162 G Glycosyl hydrolases family 18
NECCCLDA_02886 5.6e-46 ykvR S Protein of unknown function (DUF3219)
NECCCLDA_02887 6e-25 ykvS S protein conserved in bacteria
NECCCLDA_02888 2.8e-28
NECCCLDA_02889 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
NECCCLDA_02890 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NECCCLDA_02891 9.2e-89 stoA CO thiol-disulfide
NECCCLDA_02892 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NECCCLDA_02893 2.3e-09
NECCCLDA_02894 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NECCCLDA_02896 1.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
NECCCLDA_02898 7.6e-128 glcT K antiterminator
NECCCLDA_02899 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NECCCLDA_02900 2.1e-39 ptsH G phosphocarrier protein HPr
NECCCLDA_02901 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NECCCLDA_02902 7.2e-39 splA S Transcriptional regulator
NECCCLDA_02903 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
NECCCLDA_02904 1.7e-125 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NECCCLDA_02905 1.3e-258 mcpC NT chemotaxis protein
NECCCLDA_02906 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NECCCLDA_02907 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
NECCCLDA_02908 7e-120 ykwD J protein with SCP PR1 domains
NECCCLDA_02909 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NECCCLDA_02910 0.0 pilS 2.7.13.3 T Histidine kinase
NECCCLDA_02911 4.4e-222 patA 2.6.1.1 E Aminotransferase
NECCCLDA_02912 2.2e-15
NECCCLDA_02913 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NECCCLDA_02914 4.9e-84 ykyB S YkyB-like protein
NECCCLDA_02915 2.8e-238 ykuC EGP Major facilitator Superfamily
NECCCLDA_02916 1.8e-87 ykuD S protein conserved in bacteria
NECCCLDA_02917 9.4e-166 ykuE S Metallophosphoesterase
NECCCLDA_02918 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECCCLDA_02919 2e-233 ykuI T Diguanylate phosphodiesterase
NECCCLDA_02920 3.9e-37 ykuJ S protein conserved in bacteria
NECCCLDA_02921 2.2e-93 ykuK S Ribonuclease H-like
NECCCLDA_02922 3.9e-27 ykzF S Antirepressor AbbA
NECCCLDA_02923 1.6e-76 ykuL S CBS domain
NECCCLDA_02924 3.5e-168 ccpC K Transcriptional regulator
NECCCLDA_02925 1.7e-84 fld C Flavodoxin domain
NECCCLDA_02926 4.4e-174 ykuO
NECCCLDA_02927 6.7e-78 fld C Flavodoxin
NECCCLDA_02928 5.3e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NECCCLDA_02929 2.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NECCCLDA_02930 9e-37 ykuS S Belongs to the UPF0180 family
NECCCLDA_02931 8.8e-142 ykuT M Mechanosensitive ion channel
NECCCLDA_02932 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NECCCLDA_02933 1.4e-80 ykuV CO thiol-disulfide
NECCCLDA_02934 1.5e-93 rok K Repressor of ComK
NECCCLDA_02935 4.6e-145 yknT
NECCCLDA_02936 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NECCCLDA_02937 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NECCCLDA_02938 5.2e-245 moeA 2.10.1.1 H molybdopterin
NECCCLDA_02939 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NECCCLDA_02940 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NECCCLDA_02941 2.4e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NECCCLDA_02942 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NECCCLDA_02943 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NECCCLDA_02944 1.4e-114 yknW S Yip1 domain
NECCCLDA_02945 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECCCLDA_02946 2.5e-124 macB V ABC transporter, ATP-binding protein
NECCCLDA_02947 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NECCCLDA_02948 3.1e-136 fruR K Transcriptional regulator
NECCCLDA_02949 5.3e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NECCCLDA_02950 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NECCCLDA_02951 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NECCCLDA_02952 8.1e-39 ykoA
NECCCLDA_02953 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NECCCLDA_02954 1.1e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NECCCLDA_02955 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NECCCLDA_02956 1.1e-12 S Uncharacterized protein YkpC
NECCCLDA_02957 7.7e-183 mreB D Rod-share determining protein MreBH
NECCCLDA_02958 1.5e-43 abrB K of stationary sporulation gene expression
NECCCLDA_02959 1e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NECCCLDA_02960 4.4e-152 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NECCCLDA_02961 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NECCCLDA_02962 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NECCCLDA_02963 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NECCCLDA_02964 8.2e-31 ykzG S Belongs to the UPF0356 family
NECCCLDA_02965 2.1e-146 ykrA S hydrolases of the HAD superfamily
NECCCLDA_02966 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NECCCLDA_02968 1.1e-107 recN L Putative cell-wall binding lipoprotein
NECCCLDA_02969 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NECCCLDA_02970 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NECCCLDA_02971 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NECCCLDA_02972 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NECCCLDA_02973 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NECCCLDA_02974 1e-276 speA 4.1.1.19 E Arginine
NECCCLDA_02975 6.5e-41 yktA S Belongs to the UPF0223 family
NECCCLDA_02976 4.6e-117 yktB S Belongs to the UPF0637 family
NECCCLDA_02977 7.1e-26 ykzI
NECCCLDA_02978 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
NECCCLDA_02979 3.4e-77 ykzC S Acetyltransferase (GNAT) family
NECCCLDA_02980 1.1e-169 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NECCCLDA_02981 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NECCCLDA_02982 0.0 ylaA
NECCCLDA_02983 1.5e-40 ylaB
NECCCLDA_02984 2.8e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NECCCLDA_02985 1.2e-11 sigC S Putative zinc-finger
NECCCLDA_02986 2.6e-37 ylaE
NECCCLDA_02987 5.3e-21 S Family of unknown function (DUF5325)
NECCCLDA_02988 0.0 typA T GTP-binding protein TypA
NECCCLDA_02989 5.6e-47 ylaH S YlaH-like protein
NECCCLDA_02990 2.5e-32 ylaI S protein conserved in bacteria
NECCCLDA_02991 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NECCCLDA_02992 8.9e-248 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NECCCLDA_02993 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NECCCLDA_02994 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NECCCLDA_02995 8.7e-44 ylaN S Belongs to the UPF0358 family
NECCCLDA_02996 1.7e-213 ftsW D Belongs to the SEDS family
NECCCLDA_02997 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NECCCLDA_02998 8.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NECCCLDA_02999 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NECCCLDA_03000 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NECCCLDA_03001 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NECCCLDA_03002 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NECCCLDA_03003 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NECCCLDA_03004 1.5e-166 ctaG S cytochrome c oxidase
NECCCLDA_03005 7e-62 ylbA S YugN-like family
NECCCLDA_03006 2.6e-74 ylbB T COG0517 FOG CBS domain
NECCCLDA_03007 9.6e-200 ylbC S protein with SCP PR1 domains
NECCCLDA_03008 4.1e-63 ylbD S Putative coat protein
NECCCLDA_03009 6.7e-37 ylbE S YlbE-like protein
NECCCLDA_03010 1.8e-75 ylbF S Belongs to the UPF0342 family
NECCCLDA_03011 7.5e-39 ylbG S UPF0298 protein
NECCCLDA_03012 5.4e-98 rsmD 2.1.1.171 L Methyltransferase
NECCCLDA_03013 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NECCCLDA_03014 9.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
NECCCLDA_03015 1.3e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
NECCCLDA_03016 6.8e-187 ylbL T Belongs to the peptidase S16 family
NECCCLDA_03017 3.3e-228 ylbM S Belongs to the UPF0348 family
NECCCLDA_03019 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
NECCCLDA_03020 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NECCCLDA_03021 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NECCCLDA_03022 1.5e-88 ylbP K n-acetyltransferase
NECCCLDA_03023 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NECCCLDA_03024 1.5e-305 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NECCCLDA_03025 2.9e-78 mraZ K Belongs to the MraZ family
NECCCLDA_03026 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NECCCLDA_03027 3.7e-44 ftsL D Essential cell division protein
NECCCLDA_03028 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NECCCLDA_03029 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NECCCLDA_03030 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NECCCLDA_03031 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NECCCLDA_03032 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NECCCLDA_03033 5.7e-186 spoVE D Belongs to the SEDS family
NECCCLDA_03034 1.6e-199 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NECCCLDA_03035 9e-167 murB 1.3.1.98 M cell wall formation
NECCCLDA_03036 7.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NECCCLDA_03037 2.4e-103 ylxW S protein conserved in bacteria
NECCCLDA_03038 1e-102 ylxX S protein conserved in bacteria
NECCCLDA_03039 6.2e-58 sbp S small basic protein
NECCCLDA_03040 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NECCCLDA_03041 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NECCCLDA_03042 0.0 bpr O COG1404 Subtilisin-like serine proteases
NECCCLDA_03043 1.7e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NECCCLDA_03044 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NECCCLDA_03045 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NECCCLDA_03046 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NECCCLDA_03047 1e-253 argE 3.5.1.16 E Acetylornithine deacetylase
NECCCLDA_03048 2.4e-37 ylmC S sporulation protein
NECCCLDA_03049 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NECCCLDA_03050 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NECCCLDA_03051 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NECCCLDA_03052 1.3e-39 yggT S membrane
NECCCLDA_03053 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NECCCLDA_03054 2.6e-67 divIVA D Cell division initiation protein
NECCCLDA_03055 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NECCCLDA_03056 8.5e-63 dksA T COG1734 DnaK suppressor protein
NECCCLDA_03057 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NECCCLDA_03058 4.2e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NECCCLDA_03059 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NECCCLDA_03060 3.8e-230 pyrP F Xanthine uracil
NECCCLDA_03061 5.9e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NECCCLDA_03062 3.2e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NECCCLDA_03063 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NECCCLDA_03064 0.0 carB 6.3.5.5 F Belongs to the CarB family
NECCCLDA_03065 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NECCCLDA_03066 1e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NECCCLDA_03067 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NECCCLDA_03068 7.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NECCCLDA_03070 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NECCCLDA_03071 1.8e-179 cysP P phosphate transporter
NECCCLDA_03072 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NECCCLDA_03073 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NECCCLDA_03074 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NECCCLDA_03075 1.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NECCCLDA_03076 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NECCCLDA_03077 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NECCCLDA_03078 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NECCCLDA_03079 2.4e-156 yloC S stress-induced protein
NECCCLDA_03080 1.5e-40 ylzA S Belongs to the UPF0296 family
NECCCLDA_03081 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NECCCLDA_03082 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NECCCLDA_03083 7e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NECCCLDA_03084 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NECCCLDA_03085 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NECCCLDA_03086 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NECCCLDA_03087 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NECCCLDA_03088 9e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NECCCLDA_03089 7.9e-140 stp 3.1.3.16 T phosphatase
NECCCLDA_03090 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NECCCLDA_03091 7.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NECCCLDA_03092 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NECCCLDA_03093 2.6e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
NECCCLDA_03094 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NECCCLDA_03095 5.5e-59 asp S protein conserved in bacteria
NECCCLDA_03096 7.8e-302 yloV S kinase related to dihydroxyacetone kinase
NECCCLDA_03097 5.6e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NECCCLDA_03098 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NECCCLDA_03099 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NECCCLDA_03100 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NECCCLDA_03101 2.1e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NECCCLDA_03102 1.2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NECCCLDA_03103 6.1e-129 IQ reductase
NECCCLDA_03104 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NECCCLDA_03105 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NECCCLDA_03106 0.0 smc D Required for chromosome condensation and partitioning
NECCCLDA_03107 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NECCCLDA_03108 6.4e-87
NECCCLDA_03109 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NECCCLDA_03110 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NECCCLDA_03111 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NECCCLDA_03112 3.8e-35 ylqC S Belongs to the UPF0109 family
NECCCLDA_03113 6.3e-61 ylqD S YlqD protein
NECCCLDA_03114 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NECCCLDA_03115 2.7e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NECCCLDA_03116 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NECCCLDA_03117 7.9e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NECCCLDA_03118 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NECCCLDA_03119 1.8e-288 ylqG
NECCCLDA_03120 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NECCCLDA_03121 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NECCCLDA_03122 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NECCCLDA_03123 4.7e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NECCCLDA_03124 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NECCCLDA_03125 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NECCCLDA_03126 2.5e-169 xerC L tyrosine recombinase XerC
NECCCLDA_03127 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NECCCLDA_03128 8.5e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NECCCLDA_03129 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NECCCLDA_03130 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NECCCLDA_03131 3.4e-74 flgC N Belongs to the flagella basal body rod proteins family
NECCCLDA_03132 1.9e-31 fliE N Flagellar hook-basal body
NECCCLDA_03133 7e-255 fliF N The M ring may be actively involved in energy transduction
NECCCLDA_03134 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NECCCLDA_03135 2.2e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NECCCLDA_03136 3.6e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NECCCLDA_03137 1.5e-69 fliJ N Flagellar biosynthesis chaperone
NECCCLDA_03138 5.5e-35 ylxF S MgtE intracellular N domain
NECCCLDA_03139 2.5e-195 fliK N Flagellar hook-length control protein
NECCCLDA_03140 1.7e-72 flgD N Flagellar basal body rod modification protein
NECCCLDA_03141 8.2e-140 flgG N Flagellar basal body rod
NECCCLDA_03142 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NECCCLDA_03143 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NECCCLDA_03144 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NECCCLDA_03145 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NECCCLDA_03146 6e-96 fliZ N Flagellar biosynthesis protein, FliO
NECCCLDA_03147 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NECCCLDA_03148 2.2e-36 fliQ N Role in flagellar biosynthesis
NECCCLDA_03149 3.6e-132 fliR N Flagellar biosynthetic protein FliR
NECCCLDA_03150 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NECCCLDA_03151 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NECCCLDA_03152 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
NECCCLDA_03153 2.8e-157 flhG D Belongs to the ParA family
NECCCLDA_03154 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NECCCLDA_03155 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NECCCLDA_03156 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NECCCLDA_03157 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NECCCLDA_03158 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NECCCLDA_03159 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NECCCLDA_03160 4.8e-77 ylxL
NECCCLDA_03161 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NECCCLDA_03162 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NECCCLDA_03163 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NECCCLDA_03164 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NECCCLDA_03165 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NECCCLDA_03166 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NECCCLDA_03167 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NECCCLDA_03168 1e-224 rasP M zinc metalloprotease
NECCCLDA_03169 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NECCCLDA_03170 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NECCCLDA_03172 4.7e-138 spaB S Lantibiotic dehydratase, C terminus
NECCCLDA_03173 6.9e-102 spaT V ABC transporter
NECCCLDA_03174 1.3e-51 spaC2 V PFAM Lanthionine synthetase
NECCCLDA_03175 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NECCCLDA_03176 1.1e-203 nusA K Participates in both transcription termination and antitermination
NECCCLDA_03177 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NECCCLDA_03178 3.1e-47 ylxQ J ribosomal protein
NECCCLDA_03179 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NECCCLDA_03180 3.9e-44 ylxP S protein conserved in bacteria
NECCCLDA_03181 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NECCCLDA_03182 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NECCCLDA_03183 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NECCCLDA_03184 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NECCCLDA_03185 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NECCCLDA_03186 2.6e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NECCCLDA_03187 2.2e-232 pepR S Belongs to the peptidase M16 family
NECCCLDA_03188 2.6e-42 ymxH S YlmC YmxH family
NECCCLDA_03189 1.1e-161 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NECCCLDA_03190 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NECCCLDA_03191 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NECCCLDA_03192 5e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NECCCLDA_03193 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NECCCLDA_03194 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NECCCLDA_03195 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NECCCLDA_03196 4.4e-32 S YlzJ-like protein
NECCCLDA_03197 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NECCCLDA_03198 1.4e-133 ymfC K Transcriptional regulator
NECCCLDA_03199 3.8e-205 ymfD EGP Major facilitator Superfamily
NECCCLDA_03200 2.7e-233 ymfF S Peptidase M16
NECCCLDA_03201 2.4e-242 ymfH S zinc protease
NECCCLDA_03202 1.7e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NECCCLDA_03203 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NECCCLDA_03204 2.7e-143 ymfK S Protein of unknown function (DUF3388)
NECCCLDA_03205 1.9e-124 ymfM S protein conserved in bacteria
NECCCLDA_03206 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NECCCLDA_03207 2.1e-235 cinA 3.5.1.42 S Belongs to the CinA family
NECCCLDA_03208 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NECCCLDA_03209 9.1e-212 pbpX V Beta-lactamase
NECCCLDA_03210 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NECCCLDA_03211 1.9e-152 ymdB S protein conserved in bacteria
NECCCLDA_03212 1.2e-36 spoVS S Stage V sporulation protein S
NECCCLDA_03213 8.7e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NECCCLDA_03214 7.2e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NECCCLDA_03215 6.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NECCCLDA_03216 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NECCCLDA_03217 2.2e-88 cotE S Spore coat protein
NECCCLDA_03218 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NECCCLDA_03219 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NECCCLDA_03220 2e-69 S Regulatory protein YrvL
NECCCLDA_03221 1.8e-96 ymcC S Membrane
NECCCLDA_03222 2.2e-108 pksA K Transcriptional regulator
NECCCLDA_03223 3.7e-125 pksB 3.1.2.6 S Polyketide biosynthesis
NECCCLDA_03224 1.2e-160 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NECCCLDA_03226 1.6e-182 pksD Q Acyl transferase domain
NECCCLDA_03227 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NECCCLDA_03228 1.8e-37 acpK IQ Phosphopantetheine attachment site
NECCCLDA_03229 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NECCCLDA_03230 8.7e-245 pksG 2.3.3.10 I synthase
NECCCLDA_03231 1.6e-140 pksH 4.2.1.18 I enoyl-CoA hydratase
NECCCLDA_03232 1.2e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NECCCLDA_03233 0.0 rhiB IQ polyketide synthase
NECCCLDA_03234 0.0 pfaA Q Polyketide synthase of type I
NECCCLDA_03235 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
NECCCLDA_03236 0.0 dhbF IQ polyketide synthase
NECCCLDA_03237 0.0 pks13 HQ Beta-ketoacyl synthase
NECCCLDA_03238 3.1e-231 cypA C Cytochrome P450
NECCCLDA_03239 4.4e-61 ymzB
NECCCLDA_03240 1.2e-160 ymaE S Metallo-beta-lactamase superfamily
NECCCLDA_03241 3e-251 aprX O Belongs to the peptidase S8 family
NECCCLDA_03242 1.9e-07 K Transcriptional regulator
NECCCLDA_03243 1.3e-125 ymaC S Replication protein
NECCCLDA_03244 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
NECCCLDA_03245 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NECCCLDA_03246 5.4e-50 ebrA P Small Multidrug Resistance protein
NECCCLDA_03248 2.1e-46 ymaF S YmaF family
NECCCLDA_03249 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NECCCLDA_03250 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NECCCLDA_03251 8.2e-23
NECCCLDA_03252 4.5e-22 ymzA
NECCCLDA_03253 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NECCCLDA_03254 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NECCCLDA_03255 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NECCCLDA_03256 2e-109 ymaB
NECCCLDA_03257 1.1e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NECCCLDA_03258 1.7e-176 spoVK O stage V sporulation protein K
NECCCLDA_03259 6.7e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NECCCLDA_03260 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NECCCLDA_03261 1.1e-68 glnR K transcriptional
NECCCLDA_03262 7e-261 glnA 6.3.1.2 E glutamine synthetase
NECCCLDA_03263 3.8e-10
NECCCLDA_03264 5.6e-30
NECCCLDA_03265 8.5e-124
NECCCLDA_03266 2.1e-36
NECCCLDA_03267 1.7e-93 G SMI1-KNR4 cell-wall
NECCCLDA_03268 3.6e-96 ynaD J Acetyltransferase (GNAT) domain
NECCCLDA_03269 8.1e-122 ynaE S Domain of unknown function (DUF3885)
NECCCLDA_03270 1.3e-56 ynaF
NECCCLDA_03272 2.3e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NECCCLDA_03273 1.9e-253 xynT G MFS/sugar transport protein
NECCCLDA_03274 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NECCCLDA_03275 2.8e-213 xylR GK ROK family
NECCCLDA_03276 4.4e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NECCCLDA_03277 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NECCCLDA_03278 8.2e-39 yokF 3.1.31.1 L RNA catabolic process
NECCCLDA_03279 6.1e-255 iolT EGP Major facilitator Superfamily
NECCCLDA_03280 1.7e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NECCCLDA_03282 2e-82 yncE S Protein of unknown function (DUF2691)
NECCCLDA_03283 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NECCCLDA_03286 3.3e-163 S Thymidylate synthase
NECCCLDA_03288 3.6e-67 S Domain of unknown function, YrpD
NECCCLDA_03289 3.3e-48 S Domain of unknown function, YrpD
NECCCLDA_03292 7.9e-25 tatA U protein secretion
NECCCLDA_03293 1.8e-71
NECCCLDA_03294 7.5e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NECCCLDA_03296 5.9e-283 gerAA EG Spore germination protein
NECCCLDA_03297 1.8e-193 gerAB U Spore germination
NECCCLDA_03298 2.8e-216 gerLC S Spore germination protein
NECCCLDA_03299 1.4e-150 yndG S DoxX-like family
NECCCLDA_03300 5.4e-115 yndH S Domain of unknown function (DUF4166)
NECCCLDA_03301 4.4e-305 yndJ S YndJ-like protein
NECCCLDA_03303 6.8e-136 yndL S Replication protein
NECCCLDA_03304 1.7e-73 yndM S Protein of unknown function (DUF2512)
NECCCLDA_03305 4.9e-78 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NECCCLDA_03306 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NECCCLDA_03307 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NECCCLDA_03308 2.9e-111 yneB L resolvase
NECCCLDA_03309 1.3e-32 ynzC S UPF0291 protein
NECCCLDA_03310 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NECCCLDA_03311 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NECCCLDA_03312 1.8e-28 yneF S UPF0154 protein
NECCCLDA_03313 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NECCCLDA_03314 2.3e-125 ccdA O cytochrome c biogenesis protein
NECCCLDA_03315 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NECCCLDA_03316 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NECCCLDA_03317 4.2e-74 yneK S Protein of unknown function (DUF2621)
NECCCLDA_03318 2.2e-63 hspX O Spore coat protein
NECCCLDA_03319 3.9e-19 sspP S Belongs to the SspP family
NECCCLDA_03320 2.5e-14 sspO S Belongs to the SspO family
NECCCLDA_03321 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NECCCLDA_03322 1e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NECCCLDA_03324 3.1e-08 sspN S Small acid-soluble spore protein N family
NECCCLDA_03325 3.9e-35 tlp S Belongs to the Tlp family
NECCCLDA_03326 2.5e-56 yneP S Thioesterase-like superfamily
NECCCLDA_03327 2.2e-53 yneQ
NECCCLDA_03328 4.1e-49 yneR S Belongs to the HesB IscA family
NECCCLDA_03329 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NECCCLDA_03330 6.6e-69 yccU S CoA-binding protein
NECCCLDA_03331 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NECCCLDA_03332 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NECCCLDA_03333 2.3e-12
NECCCLDA_03334 8.6e-57 ynfC
NECCCLDA_03335 1.8e-251 agcS E Sodium alanine symporter
NECCCLDA_03336 1.2e-293 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NECCCLDA_03338 5.3e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NECCCLDA_03339 8.4e-290 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NECCCLDA_03340 2e-79 yngA S membrane
NECCCLDA_03341 3.5e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NECCCLDA_03342 5.5e-104 yngC S membrane-associated protein
NECCCLDA_03343 3.6e-232 nrnB S phosphohydrolase (DHH superfamily)
NECCCLDA_03344 5.9e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NECCCLDA_03345 7.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NECCCLDA_03346 3.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NECCCLDA_03347 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NECCCLDA_03348 4.7e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NECCCLDA_03349 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NECCCLDA_03350 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NECCCLDA_03351 1.5e-302 yngK T Glycosyl hydrolase-like 10
NECCCLDA_03352 3.1e-63 yngL S Protein of unknown function (DUF1360)
NECCCLDA_03353 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NECCCLDA_03354 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NECCCLDA_03360 6.7e-167 ygxA S Nucleotidyltransferase-like
NECCCLDA_03361 2.8e-55 ygzB S UPF0295 protein
NECCCLDA_03362 4e-80 perR P Belongs to the Fur family
NECCCLDA_03363 1.8e-86 bcp 1.11.1.15 O Peroxiredoxin
NECCCLDA_03364 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NECCCLDA_03365 8.7e-180 ygaE S Membrane
NECCCLDA_03366 3.1e-301 ygaD V ABC transporter
NECCCLDA_03367 1.3e-104 ygaC J Belongs to the UPF0374 family
NECCCLDA_03368 1.1e-47 ygaB S YgaB-like protein
NECCCLDA_03369 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NECCCLDA_03370 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECCCLDA_03371 6.9e-36 yfhS
NECCCLDA_03372 3.3e-210 mutY L A G-specific
NECCCLDA_03373 1.2e-185 yfhP S membrane-bound metal-dependent
NECCCLDA_03374 0.0 yfhO S Bacterial membrane protein YfhO
NECCCLDA_03375 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NECCCLDA_03376 3.7e-170 yfhM S Alpha beta hydrolase
NECCCLDA_03377 1e-47 yfhL S SdpI/YhfL protein family
NECCCLDA_03378 1.1e-89 batE T Bacterial SH3 domain homologues
NECCCLDA_03379 1.3e-44 yfhJ S WVELL protein
NECCCLDA_03380 6.2e-20 sspK S reproduction
NECCCLDA_03381 2.5e-209 yfhI EGP Major facilitator Superfamily
NECCCLDA_03383 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NECCCLDA_03384 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NECCCLDA_03385 7.9e-171 yfhF S nucleoside-diphosphate sugar epimerase
NECCCLDA_03387 6.1e-25 yfhD S YfhD-like protein
NECCCLDA_03388 1.5e-106 yfhC C nitroreductase
NECCCLDA_03389 1.1e-166 yfhB 5.3.3.17 S PhzF family
NECCCLDA_03390 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECCCLDA_03391 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECCCLDA_03392 2.8e-174 yfiY P ABC transporter substrate-binding protein
NECCCLDA_03393 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NECCCLDA_03394 4.9e-79 yfiV K transcriptional
NECCCLDA_03395 3.4e-283 yfiU EGP Major facilitator Superfamily
NECCCLDA_03396 4.7e-99 yfiT S Belongs to the metal hydrolase YfiT family
NECCCLDA_03397 1.8e-213 yfiS EGP Major facilitator Superfamily
NECCCLDA_03398 3.2e-107 yfiR K Transcriptional regulator
NECCCLDA_03399 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NECCCLDA_03400 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NECCCLDA_03401 8.3e-99 padR K transcriptional
NECCCLDA_03402 1.8e-204 V COG0842 ABC-type multidrug transport system, permease component
NECCCLDA_03403 1.3e-205 V ABC-2 family transporter protein
NECCCLDA_03404 1.1e-167 V ABC transporter, ATP-binding protein
NECCCLDA_03405 2.8e-109 KT LuxR family transcriptional regulator
NECCCLDA_03406 6.9e-188 yxjM T Histidine kinase
NECCCLDA_03407 3.5e-160 yfiE 1.13.11.2 S glyoxalase
NECCCLDA_03408 1.1e-63 mhqP S DoxX
NECCCLDA_03409 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NECCCLDA_03410 4.4e-308 yfiB3 V ABC transporter
NECCCLDA_03411 0.0 yobO M COG5434 Endopolygalacturonase
NECCCLDA_03412 8e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NECCCLDA_03413 1e-139 glvR K Helix-turn-helix domain, rpiR family
NECCCLDA_03414 2.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NECCCLDA_03415 1.1e-44 yfjA S Belongs to the WXG100 family
NECCCLDA_03416 2.3e-189 yfjB
NECCCLDA_03417 4.1e-144 yfjC
NECCCLDA_03418 1.8e-101 yfjD S Family of unknown function (DUF5381)
NECCCLDA_03419 1.9e-79 S Family of unknown function (DUF5381)
NECCCLDA_03420 2.2e-52 yfjF S UPF0060 membrane protein
NECCCLDA_03421 9.8e-25 sspH S Belongs to the SspH family
NECCCLDA_03422 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NECCCLDA_03423 1.4e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NECCCLDA_03424 1.3e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NECCCLDA_03425 1.9e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NECCCLDA_03426 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NECCCLDA_03427 1.9e-85 yfjM S Psort location Cytoplasmic, score
NECCCLDA_03428 1.8e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NECCCLDA_03429 3.9e-44 S YfzA-like protein
NECCCLDA_03430 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NECCCLDA_03431 2.9e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NECCCLDA_03432 1.7e-184 corA P Mediates influx of magnesium ions
NECCCLDA_03433 3.4e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NECCCLDA_03434 2.6e-154 pdaA G deacetylase
NECCCLDA_03435 1.1e-26 yfjT
NECCCLDA_03436 5.4e-222 yfkA S YfkB-like domain
NECCCLDA_03437 7.8e-149 yfkC M Mechanosensitive ion channel
NECCCLDA_03438 1.2e-146 yfkD S YfkD-like protein
NECCCLDA_03439 6.1e-183 cax P COG0387 Ca2 H antiporter
NECCCLDA_03440 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NECCCLDA_03441 5e-08
NECCCLDA_03442 1.7e-143 yihY S Belongs to the UPF0761 family
NECCCLDA_03443 2.4e-50 yfkI S gas vesicle protein
NECCCLDA_03444 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NECCCLDA_03445 2.1e-29 yfkK S Belongs to the UPF0435 family
NECCCLDA_03446 3.4e-206 ydiM EGP Major facilitator Superfamily
NECCCLDA_03447 3.3e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
NECCCLDA_03448 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NECCCLDA_03449 1.4e-124 yfkO C nitroreductase
NECCCLDA_03450 6.7e-133 treR K transcriptional
NECCCLDA_03451 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NECCCLDA_03452 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NECCCLDA_03453 3.6e-91 yfkQ EG Spore germination protein
NECCCLDA_03454 1.2e-180 yfkQ EG Spore germination protein
NECCCLDA_03455 2.5e-206 yfkR S spore germination
NECCCLDA_03457 1.9e-192 E Spore germination protein
NECCCLDA_03458 2.2e-252 agcS_1 E Sodium alanine symporter
NECCCLDA_03459 6e-67 yhdN S Domain of unknown function (DUF1992)
NECCCLDA_03460 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NECCCLDA_03461 3.3e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NECCCLDA_03462 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
NECCCLDA_03463 2.4e-50 yflH S Protein of unknown function (DUF3243)
NECCCLDA_03464 4.1e-19 yflI
NECCCLDA_03465 8.9e-18 yflJ S Protein of unknown function (DUF2639)
NECCCLDA_03466 3.2e-121 yflK S protein conserved in bacteria
NECCCLDA_03467 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NECCCLDA_03468 1.3e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NECCCLDA_03469 8.7e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NECCCLDA_03470 4.2e-226 citM C Citrate transporter
NECCCLDA_03471 1.7e-179 yflP S Tripartite tricarboxylate transporter family receptor
NECCCLDA_03472 2.2e-117 citT T response regulator
NECCCLDA_03473 3.7e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NECCCLDA_03474 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
NECCCLDA_03475 6.5e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NECCCLDA_03476 1.3e-57 yflT S Heat induced stress protein YflT
NECCCLDA_03477 2.9e-24 S Protein of unknown function (DUF3212)
NECCCLDA_03478 4.2e-167 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NECCCLDA_03479 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECCCLDA_03480 2.4e-168 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECCCLDA_03481 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NECCCLDA_03482 4.6e-188 yfmJ S N-terminal domain of oxidoreductase
NECCCLDA_03483 1.2e-76 yfmK 2.3.1.128 K acetyltransferase
NECCCLDA_03484 7.7e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NECCCLDA_03485 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NECCCLDA_03486 6.3e-57
NECCCLDA_03488 6.4e-19
NECCCLDA_03489 1.6e-59 isp O Subtilase family
NECCCLDA_03490 1.2e-208 yfmO EGP Major facilitator Superfamily
NECCCLDA_03491 1.4e-69 yfmP K transcriptional
NECCCLDA_03492 1.1e-72 yfmQ S Uncharacterised protein from bacillus cereus group
NECCCLDA_03493 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NECCCLDA_03494 1.1e-113 yfmS NT chemotaxis protein
NECCCLDA_03495 1.8e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NECCCLDA_03496 6.4e-241 yfnA E amino acid
NECCCLDA_03497 8.1e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NECCCLDA_03498 1.5e-204 fsr P COG0477 Permeases of the major facilitator superfamily
NECCCLDA_03499 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
NECCCLDA_03500 1.2e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NECCCLDA_03501 6.7e-178 yfnF M Nucleotide-diphospho-sugar transferase
NECCCLDA_03502 3.2e-172 yfnG 4.2.1.45 M dehydratase
NECCCLDA_03503 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
NECCCLDA_03504 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NECCCLDA_03505 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NECCCLDA_03506 1.6e-194 yetN S Protein of unknown function (DUF3900)
NECCCLDA_03508 3e-209 yetM CH FAD binding domain
NECCCLDA_03509 2.1e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
NECCCLDA_03510 1.2e-158 yetK EG EamA-like transporter family
NECCCLDA_03511 5.3e-105 yetJ S Belongs to the BI1 family
NECCCLDA_03512 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
NECCCLDA_03513 1.9e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NECCCLDA_03514 2.4e-34
NECCCLDA_03515 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NECCCLDA_03516 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NECCCLDA_03517 5.2e-122 yetF S membrane
NECCCLDA_03518 7.1e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NECCCLDA_03519 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
NECCCLDA_03520 3.2e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NECCCLDA_03521 1.2e-288 lplA G Bacterial extracellular solute-binding protein
NECCCLDA_03522 0.0 yetA
NECCCLDA_03523 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NECCCLDA_03524 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
NECCCLDA_03525 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NECCCLDA_03526 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NECCCLDA_03527 3.9e-113 yesV S Protein of unknown function, DUF624
NECCCLDA_03528 7.1e-129 yesU S Domain of unknown function (DUF1961)
NECCCLDA_03529 3.7e-128 E GDSL-like Lipase/Acylhydrolase
NECCCLDA_03530 0.0 yesS K Transcriptional regulator
NECCCLDA_03531 2.7e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NECCCLDA_03532 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
NECCCLDA_03533 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
NECCCLDA_03534 1.8e-245 yesO G Bacterial extracellular solute-binding protein
NECCCLDA_03535 6.1e-202 yesN K helix_turn_helix, arabinose operon control protein
NECCCLDA_03536 0.0 yesM 2.7.13.3 T Histidine kinase
NECCCLDA_03537 1.8e-102 yesL S Protein of unknown function, DUF624
NECCCLDA_03539 7.9e-102 yesJ K Acetyltransferase (GNAT) family
NECCCLDA_03540 5.2e-104 cotJC P Spore Coat
NECCCLDA_03541 1.5e-45 cotJB S CotJB protein
NECCCLDA_03542 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NECCCLDA_03543 4.9e-151 yesF GM NAD(P)H-binding
NECCCLDA_03544 6.9e-80 yesE S SnoaL-like domain
NECCCLDA_03545 2.1e-100 dhaR3 K Transcriptional regulator
NECCCLDA_03547 2.7e-126 yeeN K transcriptional regulatory protein
NECCCLDA_03549 8.2e-210 S Tetratricopeptide repeat
NECCCLDA_03550 8e-180 3.4.24.40 CO amine dehydrogenase activity
NECCCLDA_03551 0.0 L nucleic acid phosphodiester bond hydrolysis
NECCCLDA_03552 3e-81 S Protein of unknown function, DUF600
NECCCLDA_03553 6.1e-35
NECCCLDA_03554 4.1e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NECCCLDA_03555 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NECCCLDA_03556 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECCCLDA_03557 2.1e-146 yerO K Transcriptional regulator
NECCCLDA_03558 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NECCCLDA_03559 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NECCCLDA_03560 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NECCCLDA_03561 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NECCCLDA_03562 1.6e-123 sapB S MgtC SapB transporter
NECCCLDA_03563 3.2e-197 yerI S homoserine kinase type II (protein kinase fold)
NECCCLDA_03564 7e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
NECCCLDA_03565 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NECCCLDA_03566 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NECCCLDA_03567 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NECCCLDA_03569 8.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NECCCLDA_03570 4.8e-51 yerC S protein conserved in bacteria
NECCCLDA_03571 1.7e-187 yerB S Protein of unknown function (DUF3048) C-terminal domain
NECCCLDA_03572 0.0 yerA 3.5.4.2 F adenine deaminase
NECCCLDA_03573 2.7e-27 S Protein of unknown function (DUF2892)
NECCCLDA_03574 5.9e-200 yjeH E Amino acid permease
NECCCLDA_03575 2.2e-16 yjeH E Amino acid permease
NECCCLDA_03576 1e-72 K helix_turn_helix ASNC type
NECCCLDA_03577 1.3e-232 purD 6.3.4.13 F Belongs to the GARS family
NECCCLDA_03578 3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NECCCLDA_03579 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NECCCLDA_03580 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NECCCLDA_03581 3.6e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NECCCLDA_03582 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NECCCLDA_03583 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NECCCLDA_03584 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NECCCLDA_03585 3.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NECCCLDA_03586 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NECCCLDA_03587 5e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NECCCLDA_03588 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NECCCLDA_03589 8e-28 yebG S NETI protein
NECCCLDA_03590 8.9e-93 yebE S UPF0316 protein
NECCCLDA_03592 4.4e-117 yebC M Membrane
NECCCLDA_03593 1e-211 pbuG S permease
NECCCLDA_03594 3.3e-256 S Domain of unknown function (DUF4179)
NECCCLDA_03595 1.2e-83 K Belongs to the sigma-70 factor family. ECF subfamily
NECCCLDA_03596 1.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NECCCLDA_03597 0.0 yebA E COG1305 Transglutaminase-like enzymes
NECCCLDA_03598 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NECCCLDA_03599 4.3e-175 yeaC S COG0714 MoxR-like ATPases
NECCCLDA_03600 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NECCCLDA_03601 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NECCCLDA_03602 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NECCCLDA_03603 1.2e-175 yeaA S Protein of unknown function (DUF4003)
NECCCLDA_03604 9.9e-157 ydjP I Alpha/beta hydrolase family
NECCCLDA_03605 1.4e-34 ydjO S Cold-inducible protein YdjO
NECCCLDA_03607 2.3e-150 ydjN U Involved in the tonB-independent uptake of proteins
NECCCLDA_03608 4.5e-64 ydjM M Lytic transglycolase
NECCCLDA_03609 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NECCCLDA_03610 2.3e-257 iolT EGP Major facilitator Superfamily
NECCCLDA_03611 5.7e-194 S Ion transport 2 domain protein
NECCCLDA_03612 2.6e-148 ydjI S virion core protein (lumpy skin disease virus)
NECCCLDA_03613 3.4e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NECCCLDA_03614 9.8e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NECCCLDA_03615 1.1e-113 pspA KT Phage shock protein A
NECCCLDA_03616 1.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NECCCLDA_03617 6.7e-254 gutA G MFS/sugar transport protein
NECCCLDA_03618 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
NECCCLDA_03619 0.0 K NB-ARC domain
NECCCLDA_03620 3.6e-153 ydjC S Abhydrolase domain containing 18
NECCCLDA_03621 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NECCCLDA_03622 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NECCCLDA_03623 7.9e-129 ydiL S CAAX protease self-immunity
NECCCLDA_03624 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NECCCLDA_03625 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NECCCLDA_03626 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NECCCLDA_03627 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NECCCLDA_03628 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NECCCLDA_03629 0.0 ydiF S ABC transporter
NECCCLDA_03630 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NECCCLDA_03631 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NECCCLDA_03632 7.1e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NECCCLDA_03633 1.3e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NECCCLDA_03634 4.2e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NECCCLDA_03636 7.8e-08
NECCCLDA_03637 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NECCCLDA_03638 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NECCCLDA_03639 6.4e-139 srfAD Q thioesterase
NECCCLDA_03640 2e-49 EGP Major Facilitator Superfamily
NECCCLDA_03641 3.8e-165 EGP Major Facilitator Superfamily
NECCCLDA_03642 2.6e-84 S YcxB-like protein
NECCCLDA_03643 5.8e-161 ycxC EG EamA-like transporter family
NECCCLDA_03644 4.1e-253 ycxD K GntR family transcriptional regulator
NECCCLDA_03645 1.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NECCCLDA_03646 1.7e-114 yczE S membrane
NECCCLDA_03647 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NECCCLDA_03648 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NECCCLDA_03649 2e-125 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NECCCLDA_03650 1.9e-161 bsdA K LysR substrate binding domain
NECCCLDA_03651 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NECCCLDA_03652 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NECCCLDA_03653 4e-39 bsdD 4.1.1.61 S response to toxic substance
NECCCLDA_03654 3.5e-82 yclD
NECCCLDA_03655 2.7e-43 yclE 3.4.11.5 S Alpha beta hydrolase
NECCCLDA_03656 7.7e-97 yclE 3.4.11.5 S Alpha beta hydrolase
NECCCLDA_03657 4.1e-262 dtpT E amino acid peptide transporter
NECCCLDA_03658 1.2e-308 yclG M Pectate lyase superfamily protein
NECCCLDA_03660 3.5e-278 gerKA EG Spore germination protein
NECCCLDA_03661 3.1e-231 gerKC S spore germination
NECCCLDA_03662 3e-196 gerKB F Spore germination protein
NECCCLDA_03663 1.8e-119 yclH P ABC transporter
NECCCLDA_03664 4e-201 yclI V ABC transporter (permease) YclI
NECCCLDA_03665 4.7e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECCCLDA_03666 2.2e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NECCCLDA_03667 2e-70 S aspartate phosphatase
NECCCLDA_03671 3.8e-238 lysC 2.7.2.4 E Belongs to the aspartokinase family
NECCCLDA_03672 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECCCLDA_03673 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECCCLDA_03674 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NECCCLDA_03675 3.2e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NECCCLDA_03676 3.2e-251 ycnB EGP Major facilitator Superfamily
NECCCLDA_03677 4.2e-153 ycnC K Transcriptional regulator
NECCCLDA_03678 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NECCCLDA_03679 2.8e-45 ycnE S Monooxygenase
NECCCLDA_03680 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NECCCLDA_03681 5.1e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECCCLDA_03682 5.3e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NECCCLDA_03683 6.4e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NECCCLDA_03684 8e-149 glcU U Glucose uptake
NECCCLDA_03685 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECCCLDA_03686 9.3e-99 ycnI S protein conserved in bacteria
NECCCLDA_03687 4.6e-307 ycnJ P protein, homolog of Cu resistance protein CopC
NECCCLDA_03688 6.2e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NECCCLDA_03689 7.3e-56
NECCCLDA_03690 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NECCCLDA_03691 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NECCCLDA_03692 2.6e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NECCCLDA_03693 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NECCCLDA_03694 2.1e-09 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NECCCLDA_03695 1.7e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NECCCLDA_03696 2.8e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NECCCLDA_03697 1.3e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NECCCLDA_03699 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NECCCLDA_03700 6.7e-139 ycsF S Belongs to the UPF0271 (lamB) family
NECCCLDA_03701 2.7e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NECCCLDA_03702 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
NECCCLDA_03703 9.4e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NECCCLDA_03704 7.3e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NECCCLDA_03705 2.7e-132 kipR K Transcriptional regulator
NECCCLDA_03706 3e-116 ycsK E anatomical structure formation involved in morphogenesis
NECCCLDA_03708 3.2e-17 yczJ S biosynthesis
NECCCLDA_03709 1.5e-19 yczJ S biosynthesis
NECCCLDA_03710 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NECCCLDA_03711 1.4e-172 ydhF S Oxidoreductase
NECCCLDA_03712 0.0 mtlR K transcriptional regulator, MtlR
NECCCLDA_03713 3e-292 ydaB IQ acyl-CoA ligase
NECCCLDA_03714 2e-98 ydaC Q Methyltransferase domain
NECCCLDA_03715 3.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECCCLDA_03716 7.8e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NECCCLDA_03717 5.6e-103 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NECCCLDA_03718 6.8e-77 ydaG 1.4.3.5 S general stress protein
NECCCLDA_03719 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NECCCLDA_03720 5.1e-47 ydzA EGP Major facilitator Superfamily
NECCCLDA_03721 1.2e-73 lrpC K Transcriptional regulator
NECCCLDA_03722 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NECCCLDA_03723 7.6e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NECCCLDA_03724 4.2e-150 ydaK T Diguanylate cyclase, GGDEF domain
NECCCLDA_03725 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NECCCLDA_03726 4.5e-233 ydaM M Glycosyl transferase family group 2
NECCCLDA_03727 0.0 ydaN S Bacterial cellulose synthase subunit
NECCCLDA_03728 0.0 ydaO E amino acid
NECCCLDA_03729 1.1e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NECCCLDA_03730 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NECCCLDA_03731 2.1e-39
NECCCLDA_03732 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NECCCLDA_03734 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NECCCLDA_03735 3.2e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NECCCLDA_03737 8.9e-59 ydbB G Cupin domain
NECCCLDA_03738 2.8e-63 ydbC S Domain of unknown function (DUF4937
NECCCLDA_03739 3.5e-154 ydbD P Catalase
NECCCLDA_03740 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NECCCLDA_03741 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NECCCLDA_03742 3.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
NECCCLDA_03743 4.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NECCCLDA_03744 9.7e-181 ydbI S AI-2E family transporter
NECCCLDA_03745 8e-171 ydbJ V ABC transporter, ATP-binding protein
NECCCLDA_03746 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NECCCLDA_03747 2.7e-52 ydbL
NECCCLDA_03748 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NECCCLDA_03749 1.1e-18 S Fur-regulated basic protein B
NECCCLDA_03750 2.2e-07 S Fur-regulated basic protein A
NECCCLDA_03751 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NECCCLDA_03752 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NECCCLDA_03753 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NECCCLDA_03754 2.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NECCCLDA_03755 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NECCCLDA_03756 2.1e-82 ydbS S Bacterial PH domain
NECCCLDA_03757 3.7e-263 ydbT S Membrane
NECCCLDA_03758 2.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NECCCLDA_03759 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NECCCLDA_03760 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NECCCLDA_03761 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NECCCLDA_03762 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NECCCLDA_03763 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NECCCLDA_03764 1.3e-143 rsbR T Positive regulator of sigma-B
NECCCLDA_03765 5.2e-57 rsbS T antagonist
NECCCLDA_03766 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NECCCLDA_03767 3.5e-188 rsbU 3.1.3.3 KT phosphatase
NECCCLDA_03768 1.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
NECCCLDA_03769 7.8e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NECCCLDA_03770 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NECCCLDA_03771 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NECCCLDA_03772 0.0 yhgF K COG2183 Transcriptional accessory protein
NECCCLDA_03773 8.9e-83 ydcK S Belongs to the SprT family
NECCCLDA_03781 3.1e-161 yddH CBM50 M Lysozyme-like
NECCCLDA_03782 3.4e-31 yddI
NECCCLDA_03783 1.3e-63 S Domain of unknown function with cystatin-like fold (DUF4467)
NECCCLDA_03784 2.1e-24 S B-1 B cell differentiation
NECCCLDA_03785 1.4e-142 J tRNA cytidylyltransferase activity
NECCCLDA_03786 2.6e-73 S response regulator aspartate phosphatase
NECCCLDA_03788 1e-36 N HicA toxin of bacterial toxin-antitoxin,
NECCCLDA_03789 1.5e-17
NECCCLDA_03790 9.8e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NECCCLDA_03791 8.7e-30 cspL K Cold shock
NECCCLDA_03792 6.1e-79 carD K Transcription factor
NECCCLDA_03793 3.5e-136 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NECCCLDA_03794 1.8e-159 rhaS5 K AraC-like ligand binding domain
NECCCLDA_03795 3.7e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NECCCLDA_03796 8.1e-165 ydeE K AraC family transcriptional regulator
NECCCLDA_03797 3.6e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECCCLDA_03798 9.3e-218 ydeG EGP Major facilitator superfamily
NECCCLDA_03799 2.1e-45 ydeH
NECCCLDA_03800 2.1e-103 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NECCCLDA_03801 7.1e-113
NECCCLDA_03802 5.9e-152 ydeK EG -transporter
NECCCLDA_03803 6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECCCLDA_03804 2.7e-73 maoC I N-terminal half of MaoC dehydratase
NECCCLDA_03805 2.5e-104 ydeN S Serine hydrolase
NECCCLDA_03806 1.2e-55 K HxlR-like helix-turn-helix
NECCCLDA_03807 1.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NECCCLDA_03808 1.8e-56 arsR K transcriptional
NECCCLDA_03809 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NECCCLDA_03810 9.8e-146 ydfB J GNAT acetyltransferase
NECCCLDA_03811 8.3e-149 lytR K Transcriptional regulator
NECCCLDA_03812 4.5e-122 nodB1 G deacetylase
NECCCLDA_03813 2.8e-157
NECCCLDA_03814 4.5e-213 T GHKL domain
NECCCLDA_03815 6.8e-123 T Transcriptional regulatory protein, C terminal
NECCCLDA_03816 7.6e-150 ydfC EG EamA-like transporter family
NECCCLDA_03817 6.8e-270 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECCCLDA_03818 1.4e-115 ydfE S Flavin reductase like domain
NECCCLDA_03819 3.9e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NECCCLDA_03820 3.4e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NECCCLDA_03821 7.7e-179 ydfH 2.7.13.3 T Histidine kinase
NECCCLDA_03822 5.5e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NECCCLDA_03823 0.0 ydfJ S drug exporters of the RND superfamily
NECCCLDA_03824 8.5e-117 S Protein of unknown function (DUF554)
NECCCLDA_03825 1.2e-143 K Bacterial transcription activator, effector binding domain
NECCCLDA_03826 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NECCCLDA_03827 1.2e-109 ydfN C nitroreductase
NECCCLDA_03828 5.8e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NECCCLDA_03829 8.8e-63 mhqP S DoxX
NECCCLDA_03830 1.7e-54 traF CO Thioredoxin
NECCCLDA_03831 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NECCCLDA_03832 6.3e-29
NECCCLDA_03834 4.4e-118 ydfR S Protein of unknown function (DUF421)
NECCCLDA_03835 1.5e-121 ydfS S Protein of unknown function (DUF421)
NECCCLDA_03836 1.7e-67 cotP O Belongs to the small heat shock protein (HSP20) family
NECCCLDA_03837 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
NECCCLDA_03838 2.5e-32 ydgB S Spore germination protein gerPA/gerPF
NECCCLDA_03839 4.5e-98 K Bacterial regulatory proteins, tetR family
NECCCLDA_03840 2.1e-52 S DoxX-like family
NECCCLDA_03841 4.2e-83 yycN 2.3.1.128 K Acetyltransferase
NECCCLDA_03842 2.2e-304 expZ S ABC transporter
NECCCLDA_03843 5.8e-250 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NECCCLDA_03844 4.7e-88 dinB S DinB family
NECCCLDA_03845 1.5e-78 K helix_turn_helix multiple antibiotic resistance protein
NECCCLDA_03846 0.0 ydgH S drug exporters of the RND superfamily
NECCCLDA_03847 1e-113 drgA C nitroreductase
NECCCLDA_03848 2.4e-69 ydgJ K Winged helix DNA-binding domain
NECCCLDA_03849 2.2e-208 tcaB EGP Major facilitator Superfamily
NECCCLDA_03850 1.2e-121 ydhB S membrane transporter protein
NECCCLDA_03851 1.6e-120 ydhC K FCD
NECCCLDA_03852 1.4e-242 ydhD M Glycosyl hydrolase
NECCCLDA_03853 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NECCCLDA_03854 6.2e-123
NECCCLDA_03855 9.9e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NECCCLDA_03856 1.6e-66 frataxin S Domain of unknown function (DU1801)
NECCCLDA_03858 2.9e-79 K Acetyltransferase (GNAT) domain
NECCCLDA_03859 1.7e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NECCCLDA_03860 2.1e-97 ydhK M Protein of unknown function (DUF1541)
NECCCLDA_03861 1e-199 pbuE EGP Major facilitator Superfamily
NECCCLDA_03862 7.9e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NECCCLDA_03863 4.3e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NECCCLDA_03864 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NECCCLDA_03865 1.8e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECCCLDA_03866 3.7e-131 ydhQ K UTRA
NECCCLDA_03867 3.3e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NECCCLDA_03868 7.6e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
NECCCLDA_03869 2.2e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NECCCLDA_03870 2.3e-156 ydhU P Catalase
NECCCLDA_03873 3.9e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NECCCLDA_03875 3e-160 ybaS 1.1.1.58 S Na -dependent transporter
NECCCLDA_03876 2.9e-134 ybbA S Putative esterase
NECCCLDA_03877 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECCCLDA_03878 5.3e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECCCLDA_03879 4e-165 feuA P Iron-uptake system-binding protein
NECCCLDA_03880 3e-303 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NECCCLDA_03881 1.3e-237 ybbC 3.2.1.52 S protein conserved in bacteria
NECCCLDA_03882 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NECCCLDA_03883 9.2e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NECCCLDA_03884 1.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NECCCLDA_03885 1.2e-149 ybbH K transcriptional
NECCCLDA_03886 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NECCCLDA_03887 1.9e-86 ybbJ J acetyltransferase
NECCCLDA_03888 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NECCCLDA_03894 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NECCCLDA_03895 6.3e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NECCCLDA_03896 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NECCCLDA_03897 3.4e-224 ybbR S protein conserved in bacteria
NECCCLDA_03898 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NECCCLDA_03899 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NECCCLDA_03900 2.1e-171 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NECCCLDA_03901 3.2e-118 adaA 3.2.2.21 K Transcriptional regulator
NECCCLDA_03902 2.6e-97 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NECCCLDA_03903 2.2e-271 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NECCCLDA_03904 0.0 ybcC S Belongs to the UPF0753 family
NECCCLDA_03905 1.5e-92 can 4.2.1.1 P carbonic anhydrase
NECCCLDA_03907 1.1e-46
NECCCLDA_03908 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
NECCCLDA_03909 5.1e-50 ybzH K Helix-turn-helix domain
NECCCLDA_03910 1.3e-202 ybcL EGP Major facilitator Superfamily
NECCCLDA_03911 5.4e-56
NECCCLDA_03913 3.7e-137 KLT Protein tyrosine kinase
NECCCLDA_03914 1.9e-150 ybdN
NECCCLDA_03915 9.8e-214 ybdO S Domain of unknown function (DUF4885)
NECCCLDA_03916 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NECCCLDA_03917 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
NECCCLDA_03918 4.9e-30 ybxH S Family of unknown function (DUF5370)
NECCCLDA_03919 5.2e-150 ybxI 3.5.2.6 V beta-lactamase
NECCCLDA_03920 7.8e-246 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NECCCLDA_03921 4.9e-41 ybyB
NECCCLDA_03922 6.8e-290 ybeC E amino acid
NECCCLDA_03923 1e-162 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NECCCLDA_03924 3.6e-257 glpT G -transporter
NECCCLDA_03925 1.5e-34 S Protein of unknown function (DUF2651)
NECCCLDA_03926 3.7e-168 ybfA 3.4.15.5 K FR47-like protein
NECCCLDA_03927 3.5e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
NECCCLDA_03929 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
NECCCLDA_03930 3.7e-160 ybfH EG EamA-like transporter family
NECCCLDA_03931 3.3e-144 msmR K AraC-like ligand binding domain
NECCCLDA_03932 8e-148 draG 3.2.2.24 O ADP-ribosylglycohydrolase
NECCCLDA_03933 1.8e-77 M nucleic acid phosphodiester bond hydrolysis
NECCCLDA_03934 5.2e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NECCCLDA_03935 2e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NECCCLDA_03937 2.2e-165 S Alpha/beta hydrolase family
NECCCLDA_03938 2.7e-94 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NECCCLDA_03939 2.7e-85 ybfM S SNARE associated Golgi protein
NECCCLDA_03940 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NECCCLDA_03941 4.6e-45 ybfN
NECCCLDA_03942 1.3e-249 S Erythromycin esterase
NECCCLDA_03943 3.9e-192 yceA S Belongs to the UPF0176 family
NECCCLDA_03944 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NECCCLDA_03945 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NECCCLDA_03946 5.9e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NECCCLDA_03947 1.4e-127 K UTRA
NECCCLDA_03948 4.5e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NECCCLDA_03949 6.7e-262 mmuP E amino acid
NECCCLDA_03950 2.5e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NECCCLDA_03952 2.8e-255 agcS E Sodium alanine symporter
NECCCLDA_03953 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
NECCCLDA_03954 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
NECCCLDA_03955 9e-170 glnL T Regulator
NECCCLDA_03956 7.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NECCCLDA_03957 6.9e-273 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NECCCLDA_03958 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NECCCLDA_03959 2.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NECCCLDA_03960 6.1e-123 ycbG K FCD
NECCCLDA_03961 2e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
NECCCLDA_03962 6.7e-178 ycbJ S Macrolide 2'-phosphotransferase
NECCCLDA_03963 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NECCCLDA_03964 3.9e-165 eamA1 EG spore germination
NECCCLDA_03965 7.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECCCLDA_03966 1.1e-167 T PhoQ Sensor
NECCCLDA_03967 1.2e-163 ycbN V ABC transporter, ATP-binding protein
NECCCLDA_03968 5.1e-114 S ABC-2 family transporter protein
NECCCLDA_03969 8.2e-53 ycbP S Protein of unknown function (DUF2512)
NECCCLDA_03970 2.2e-78 sleB 3.5.1.28 M Cell wall
NECCCLDA_03971 1.2e-134 ycbR T vWA found in TerF C terminus
NECCCLDA_03972 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NECCCLDA_03973 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NECCCLDA_03974 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NECCCLDA_03975 3.4e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NECCCLDA_03976 8.9e-201 ycbU E Selenocysteine lyase
NECCCLDA_03977 3e-225 lmrB EGP the major facilitator superfamily
NECCCLDA_03978 6.3e-102 yxaF K Transcriptional regulator
NECCCLDA_03979 7.6e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NECCCLDA_03980 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NECCCLDA_03981 3.4e-59 S RDD family
NECCCLDA_03982 1.4e-198 yccF K DNA-templated transcriptional preinitiation complex assembly
NECCCLDA_03983 6.6e-152 2.7.13.3 T GHKL domain
NECCCLDA_03984 1.2e-126 lytR_2 T LytTr DNA-binding domain
NECCCLDA_03985 2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NECCCLDA_03986 5.5e-201 natB CP ABC-2 family transporter protein
NECCCLDA_03987 2.3e-173 yccK C Aldo keto reductase
NECCCLDA_03988 6.6e-177 ycdA S Domain of unknown function (DUF5105)
NECCCLDA_03989 1.2e-269 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NECCCLDA_03990 4.3e-259 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NECCCLDA_03991 4e-92 cwlK M D-alanyl-D-alanine carboxypeptidase
NECCCLDA_03992 2.7e-173 S response regulator aspartate phosphatase
NECCCLDA_03993 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
NECCCLDA_03994 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NECCCLDA_03995 1.1e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
NECCCLDA_03996 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NECCCLDA_03997 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NECCCLDA_03998 9.5e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NECCCLDA_03999 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NECCCLDA_04000 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NECCCLDA_04001 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
NECCCLDA_04002 3.1e-136 terC P Protein of unknown function (DUF475)
NECCCLDA_04003 0.0 yceG S Putative component of 'biosynthetic module'
NECCCLDA_04004 2e-192 yceH P Belongs to the TelA family
NECCCLDA_04005 4.3e-217 naiP P Uncharacterised MFS-type transporter YbfB
NECCCLDA_04006 2.4e-204 yceJ EGP Uncharacterised MFS-type transporter YbfB
NECCCLDA_04007 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NECCCLDA_04008 5.1e-229 proV 3.6.3.32 E glycine betaine
NECCCLDA_04009 1.3e-127 opuAB P glycine betaine
NECCCLDA_04010 5.3e-164 opuAC E glycine betaine
NECCCLDA_04011 4.1e-217 amhX S amidohydrolase
NECCCLDA_04012 8.1e-255 ycgA S Membrane
NECCCLDA_04013 4.1e-81 ycgB
NECCCLDA_04014 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NECCCLDA_04015 9.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NECCCLDA_04016 1.6e-291 lctP C L-lactate permease
NECCCLDA_04017 3.9e-263 mdr EGP Major facilitator Superfamily
NECCCLDA_04018 1.3e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
NECCCLDA_04019 6.8e-113 ycgF E Lysine exporter protein LysE YggA
NECCCLDA_04020 4.9e-150 yqcI S YqcI/YcgG family
NECCCLDA_04021 1.4e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NECCCLDA_04022 2.4e-112 ycgI S Domain of unknown function (DUF1989)
NECCCLDA_04023 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NECCCLDA_04024 4.7e-108 tmrB S AAA domain
NECCCLDA_04025 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NECCCLDA_04026 9e-144 yafE Q ubiE/COQ5 methyltransferase family
NECCCLDA_04027 1.3e-176 oxyR3 K LysR substrate binding domain
NECCCLDA_04028 4.2e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NECCCLDA_04029 6.4e-145 ycgL S Predicted nucleotidyltransferase
NECCCLDA_04030 5.1e-170 ycgM E Proline dehydrogenase
NECCCLDA_04031 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NECCCLDA_04032 8.8e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NECCCLDA_04033 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NECCCLDA_04034 3.5e-144 ycgQ S membrane
NECCCLDA_04035 1.2e-139 ycgR S permeases
NECCCLDA_04036 3.2e-158 I alpha/beta hydrolase fold
NECCCLDA_04037 3.2e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NECCCLDA_04038 7.6e-277 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NECCCLDA_04039 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NECCCLDA_04040 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NECCCLDA_04041 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECCCLDA_04042 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NECCCLDA_04043 3.2e-220 nasA P COG2223 Nitrate nitrite transporter
NECCCLDA_04044 6.9e-167 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NECCCLDA_04045 1.8e-99 yciB M ErfK YbiS YcfS YnhG
NECCCLDA_04046 7e-228 yciC S GTPases (G3E family)
NECCCLDA_04047 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
NECCCLDA_04048 3.4e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NECCCLDA_04050 9.6e-77 yckC S membrane
NECCCLDA_04051 3.5e-52 yckD S Protein of unknown function (DUF2680)
NECCCLDA_04052 6.1e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECCCLDA_04053 6.5e-69 nin S Competence protein J (ComJ)
NECCCLDA_04054 1.3e-70 nucA M Deoxyribonuclease NucA/NucB
NECCCLDA_04055 1e-179 tlpC 2.7.13.3 NT chemotaxis protein
NECCCLDA_04056 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NECCCLDA_04057 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NECCCLDA_04058 1.3e-63 hxlR K transcriptional
NECCCLDA_04059 2.1e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
NECCCLDA_04060 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NECCCLDA_04061 1.2e-84 gerD
NECCCLDA_04062 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NECCCLDA_04063 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NECCCLDA_04064 9.7e-66 ybaK S Protein of unknown function (DUF2521)
NECCCLDA_04065 3.4e-143 ybaJ Q Methyltransferase domain
NECCCLDA_04066 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NECCCLDA_04067 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NECCCLDA_04068 6.3e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NECCCLDA_04069 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NECCCLDA_04070 4.1e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NECCCLDA_04071 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NECCCLDA_04072 3.6e-58 rplQ J Ribosomal protein L17
NECCCLDA_04073 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NECCCLDA_04074 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NECCCLDA_04075 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NECCCLDA_04076 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NECCCLDA_04077 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NECCCLDA_04078 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NECCCLDA_04079 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NECCCLDA_04080 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NECCCLDA_04081 1.8e-72 rplO J binds to the 23S rRNA
NECCCLDA_04082 1.9e-23 rpmD J Ribosomal protein L30
NECCCLDA_04083 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NECCCLDA_04084 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NECCCLDA_04085 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NECCCLDA_04086 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NECCCLDA_04087 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NECCCLDA_04088 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NECCCLDA_04089 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NECCCLDA_04090 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NECCCLDA_04091 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NECCCLDA_04092 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NECCCLDA_04093 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NECCCLDA_04094 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NECCCLDA_04095 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NECCCLDA_04096 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NECCCLDA_04097 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NECCCLDA_04098 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NECCCLDA_04099 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
NECCCLDA_04100 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NECCCLDA_04101 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NECCCLDA_04102 2.6e-180 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NECCCLDA_04103 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NECCCLDA_04104 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NECCCLDA_04105 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NECCCLDA_04106 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NECCCLDA_04107 8.8e-32 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NECCCLDA_04108 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NECCCLDA_04109 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NECCCLDA_04110 4.1e-107 rsmC 2.1.1.172 J Methyltransferase
NECCCLDA_04111 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NECCCLDA_04112 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NECCCLDA_04113 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NECCCLDA_04114 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NECCCLDA_04115 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NECCCLDA_04116 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NECCCLDA_04117 4.4e-115 sigH K Belongs to the sigma-70 factor family
NECCCLDA_04118 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NECCCLDA_04119 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NECCCLDA_04120 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NECCCLDA_04121 2.7e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NECCCLDA_04122 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
NECCCLDA_04123 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NECCCLDA_04124 3.5e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NECCCLDA_04125 5.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NECCCLDA_04126 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NECCCLDA_04127 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NECCCLDA_04128 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NECCCLDA_04129 0.0 clpC O Belongs to the ClpA ClpB family
NECCCLDA_04130 1.1e-200 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NECCCLDA_04131 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NECCCLDA_04132 2.9e-76 ctsR K Belongs to the CtsR family
NECCCLDA_04133 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NECCCLDA_04134 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NECCCLDA_04135 4.1e-30 yazB K transcriptional
NECCCLDA_04136 7.9e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NECCCLDA_04137 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NECCCLDA_04138 1.7e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NECCCLDA_04139 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NECCCLDA_04140 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NECCCLDA_04141 9.1e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NECCCLDA_04142 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NECCCLDA_04143 5e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NECCCLDA_04144 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NECCCLDA_04145 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NECCCLDA_04146 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NECCCLDA_04147 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NECCCLDA_04148 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NECCCLDA_04149 6.3e-185 KLT serine threonine protein kinase
NECCCLDA_04150 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NECCCLDA_04151 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NECCCLDA_04154 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NECCCLDA_04155 1.1e-44 divIC D Septum formation initiator
NECCCLDA_04156 2.5e-107 yabQ S spore cortex biosynthesis protein
NECCCLDA_04157 1.5e-49 yabP S Sporulation protein YabP
NECCCLDA_04158 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NECCCLDA_04159 1.2e-242 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NECCCLDA_04160 1.1e-281 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NECCCLDA_04161 1.5e-92 spoVT K stage V sporulation protein
NECCCLDA_04162 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NECCCLDA_04163 2.4e-39 yabK S Peptide ABC transporter permease
NECCCLDA_04164 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NECCCLDA_04165 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NECCCLDA_04166 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NECCCLDA_04167 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NECCCLDA_04168 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NECCCLDA_04169 6.6e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NECCCLDA_04170 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NECCCLDA_04171 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NECCCLDA_04172 7.8e-39 veg S protein conserved in bacteria
NECCCLDA_04173 1.6e-136 yabG S peptidase
NECCCLDA_04174 7.6e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NECCCLDA_04175 1e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NECCCLDA_04176 2e-167 rpfB GH23 T protein conserved in bacteria
NECCCLDA_04177 4.5e-143 tatD L hydrolase, TatD
NECCCLDA_04178 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NECCCLDA_04179 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NECCCLDA_04180 4.6e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NECCCLDA_04181 1.5e-49 yazA L endonuclease containing a URI domain
NECCCLDA_04182 1.2e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
NECCCLDA_04183 4.8e-31 yabA L Involved in initiation control of chromosome replication
NECCCLDA_04184 6.1e-146 yaaT S stage 0 sporulation protein
NECCCLDA_04185 3.1e-181 holB 2.7.7.7 L DNA polymerase III
NECCCLDA_04186 1.5e-71 yaaR S protein conserved in bacteria
NECCCLDA_04187 2.2e-54 yaaQ S protein conserved in bacteria
NECCCLDA_04188 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NECCCLDA_04189 1.1e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NECCCLDA_04190 4.9e-202 yaaN P Belongs to the TelA family
NECCCLDA_04191 2.4e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NECCCLDA_04192 2.2e-30 csfB S Inhibitor of sigma-G Gin
NECCCLDA_04193 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NECCCLDA_04194 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NECCCLDA_04195 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NECCCLDA_04196 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NECCCLDA_04197 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NECCCLDA_04198 1.6e-82 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NECCCLDA_04199 1.9e-95 yaaI Q COG1335 Amidases related to nicotinamidase
NECCCLDA_04200 5.3e-213 yaaH M Glycoside Hydrolase Family
NECCCLDA_04201 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NECCCLDA_04202 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NECCCLDA_04203 1.3e-09
NECCCLDA_04204 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NECCCLDA_04205 6.8e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NECCCLDA_04206 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NECCCLDA_04207 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NECCCLDA_04208 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NECCCLDA_04209 1.3e-179 yaaC S YaaC-like Protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)