ORF_ID e_value Gene_name EC_number CAZy COGs Description
NPKDGBBO_00001 2.6e-216 ywhK S Membrane
NPKDGBBO_00002 2.2e-50
NPKDGBBO_00003 2.4e-19 S D-Ala-teichoic acid biosynthesis protein
NPKDGBBO_00004 1.2e-293 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPKDGBBO_00005 3e-242 dltB M MBOAT, membrane-bound O-acyltransferase family
NPKDGBBO_00006 5.7e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPKDGBBO_00007 3.5e-249 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPKDGBBO_00008 3.2e-175 pbpX2 V Beta-lactamase
NPKDGBBO_00010 5.9e-10
NPKDGBBO_00011 1.5e-118 S CAAX protease self-immunity
NPKDGBBO_00012 4.9e-29
NPKDGBBO_00013 1.9e-50
NPKDGBBO_00014 2.2e-125 S Protein of unknown function (DUF975)
NPKDGBBO_00015 3.6e-146 lysA2 M Glycosyl hydrolases family 25
NPKDGBBO_00016 3.3e-289 ytgP S Polysaccharide biosynthesis protein
NPKDGBBO_00017 1.1e-36
NPKDGBBO_00018 1.1e-228 XK27_06780 V ABC transporter permease
NPKDGBBO_00019 1.3e-113 XK27_06780 V ABC transporter permease
NPKDGBBO_00020 5.4e-124 XK27_06785 V ABC transporter, ATP-binding protein
NPKDGBBO_00021 3e-213 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPKDGBBO_00022 7.2e-172 S Alpha/beta hydrolase of unknown function (DUF915)
NPKDGBBO_00023 0.0 clpE O AAA domain (Cdc48 subfamily)
NPKDGBBO_00024 4.9e-119 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NPKDGBBO_00025 2.4e-128
NPKDGBBO_00026 1.1e-221 cycA E Amino acid permease
NPKDGBBO_00027 3.9e-246 yifK E Amino acid permease
NPKDGBBO_00028 8.6e-41 gcvR T Belongs to the UPF0237 family
NPKDGBBO_00029 4.5e-247 XK27_08635 S UPF0210 protein
NPKDGBBO_00030 1.4e-237 G Bacterial extracellular solute-binding protein
NPKDGBBO_00031 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NPKDGBBO_00032 1.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NPKDGBBO_00033 3.2e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPKDGBBO_00034 3.2e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NPKDGBBO_00035 4.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPKDGBBO_00036 3.7e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPKDGBBO_00037 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPKDGBBO_00038 3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPKDGBBO_00039 2.3e-33 S RelB antitoxin
NPKDGBBO_00040 1.5e-68 K Acetyltransferase (GNAT) domain
NPKDGBBO_00041 1.2e-70 L Transposase and inactivated derivatives, IS30 family
NPKDGBBO_00042 1.8e-32 M NlpC/P60 family
NPKDGBBO_00043 1.3e-89 2.7.7.65 T phosphorelay sensor kinase activity
NPKDGBBO_00044 2.6e-133 cbiQ P Cobalt transport protein
NPKDGBBO_00045 7e-158 P ABC transporter
NPKDGBBO_00046 1.2e-151 cbiO2 P ABC transporter
NPKDGBBO_00047 4.1e-47 L Psort location Cytoplasmic, score
NPKDGBBO_00048 6.7e-259 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NPKDGBBO_00049 1.3e-185 S SLAP domain
NPKDGBBO_00050 7e-186 S Bacteriocin helveticin-J
NPKDGBBO_00051 2.7e-160
NPKDGBBO_00052 1.2e-164 L Transposase
NPKDGBBO_00053 6e-16 lhr L DEAD DEAH box helicase
NPKDGBBO_00054 5.1e-60
NPKDGBBO_00055 5.3e-141 S Uncharacterized protein conserved in bacteria (DUF2263)
NPKDGBBO_00056 3e-26 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPKDGBBO_00057 1.2e-13 L Transposase
NPKDGBBO_00058 2e-129 K UTRA
NPKDGBBO_00059 7.6e-180 S Oxidoreductase family, NAD-binding Rossmann fold
NPKDGBBO_00060 1.3e-24 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NPKDGBBO_00061 4.3e-194 asnA 6.3.1.1 F aspartate--ammonia ligase
NPKDGBBO_00062 4.8e-204 4.2.1.126 S Bacterial protein of unknown function (DUF871)
NPKDGBBO_00065 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPKDGBBO_00066 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPKDGBBO_00067 8.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPKDGBBO_00068 1.8e-57
NPKDGBBO_00069 1.4e-86
NPKDGBBO_00070 3.8e-74 yheS_2 S ATPases associated with a variety of cellular activities
NPKDGBBO_00071 2.7e-71 yheS_2 S ATPases associated with a variety of cellular activities
NPKDGBBO_00072 6.6e-176 XK27_05540 S DUF218 domain
NPKDGBBO_00073 1.1e-78
NPKDGBBO_00074 4.6e-109
NPKDGBBO_00075 1.3e-137 EG EamA-like transporter family
NPKDGBBO_00076 3.6e-82 M NlpC/P60 family
NPKDGBBO_00077 2.6e-64 M Glycosyltransferase, group 2 family protein
NPKDGBBO_00078 1.1e-76 MA20_43635 M Capsular polysaccharide synthesis protein
NPKDGBBO_00079 2.6e-80 M Glycosyltransferase, group 2 family protein
NPKDGBBO_00080 6.1e-165 M Glycosyl transferases group 1
NPKDGBBO_00081 1.4e-121 rfbP M Bacterial sugar transferase
NPKDGBBO_00082 3.9e-99
NPKDGBBO_00083 2.5e-278 S O-antigen ligase like membrane protein
NPKDGBBO_00084 9.6e-25
NPKDGBBO_00085 1.2e-94 gmk2 2.7.4.8 F Guanylate kinase homologues.
NPKDGBBO_00086 7e-90 M NlpC/P60 family
NPKDGBBO_00087 2.1e-31 S Archaea bacterial proteins of unknown function
NPKDGBBO_00094 4.8e-221 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
NPKDGBBO_00095 6.4e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
NPKDGBBO_00096 3.7e-177 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPKDGBBO_00097 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPKDGBBO_00098 2.3e-29 secG U Preprotein translocase
NPKDGBBO_00099 3.1e-275 pepV 3.5.1.18 E dipeptidase PepV
NPKDGBBO_00100 5.2e-192 V Beta-lactamase
NPKDGBBO_00101 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NPKDGBBO_00102 3.3e-47
NPKDGBBO_00103 8.1e-137
NPKDGBBO_00104 5e-78 XK27_09675 K Acetyltransferase (GNAT) domain
NPKDGBBO_00105 4e-53 S Protein of unknown function (DUF3021)
NPKDGBBO_00106 1.6e-76 K LytTr DNA-binding domain
NPKDGBBO_00107 7.2e-43
NPKDGBBO_00108 8e-125 magIII L Base excision DNA repair protein, HhH-GPD family
NPKDGBBO_00109 6.5e-57 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NPKDGBBO_00110 1.3e-201 folE 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 F GTP cyclohydrolase 1
NPKDGBBO_00111 2.4e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NPKDGBBO_00112 3.9e-201 folP 2.5.1.15 H dihydropteroate synthase
NPKDGBBO_00113 3.1e-98 3.6.1.55, 3.6.1.67 F NUDIX domain
NPKDGBBO_00114 1.5e-48 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
NPKDGBBO_00115 3.4e-25 S Uncharacterized protein conserved in bacteria (DUF2255)
NPKDGBBO_00116 6e-112 papP P ABC transporter, permease protein
NPKDGBBO_00117 4e-79 P ABC transporter permease
NPKDGBBO_00118 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPKDGBBO_00119 9.1e-161 cjaA ET ABC transporter substrate-binding protein
NPKDGBBO_00120 3.6e-73 L Helix-turn-helix domain
NPKDGBBO_00121 4.2e-197 L hmm pf00665
NPKDGBBO_00122 1.7e-90 dam 2.1.1.72 H Site-specific DNA-methyltransferase (adenine-specific)
NPKDGBBO_00124 9.9e-117 L Integrase
NPKDGBBO_00126 4.1e-156 L Transposase
NPKDGBBO_00127 9.4e-30 S ABC transporter
NPKDGBBO_00128 1.1e-199 V ABC-type multidrug transport system, ATPase and permease components
NPKDGBBO_00129 1.9e-55 P ABC transporter
NPKDGBBO_00130 1.1e-126 pgm3 G Phosphoglycerate mutase family
NPKDGBBO_00131 7.5e-19 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NPKDGBBO_00132 5.9e-241 S response to antibiotic
NPKDGBBO_00133 2.8e-125
NPKDGBBO_00134 5e-82 3.6.3.8 P P-type ATPase
NPKDGBBO_00135 3.1e-22 3.6.3.8 P P-type ATPase
NPKDGBBO_00136 3.6e-98 3.6.3.8 P P-type ATPase
NPKDGBBO_00137 1.7e-20
NPKDGBBO_00138 1.6e-14
NPKDGBBO_00139 7.8e-188 ansA 3.5.1.1 EJ L-asparaginase, type I
NPKDGBBO_00140 1.8e-131 glvR K Helix-turn-helix domain, rpiR family
NPKDGBBO_00141 1.7e-267 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
NPKDGBBO_00142 2.6e-24
NPKDGBBO_00143 1.9e-46
NPKDGBBO_00144 2.8e-93
NPKDGBBO_00145 0.0 cadA P P-type ATPase
NPKDGBBO_00146 1.3e-205 napA P Sodium/hydrogen exchanger family
NPKDGBBO_00147 1.5e-49 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NPKDGBBO_00148 4.7e-47 S YoeB-like toxin of bacterial type II toxin-antitoxin system
NPKDGBBO_00149 1.5e-267 V ABC transporter transmembrane region
NPKDGBBO_00151 4e-81 S Putative adhesin
NPKDGBBO_00152 5.9e-160 mutR K Helix-turn-helix XRE-family like proteins
NPKDGBBO_00153 6.4e-47
NPKDGBBO_00154 4.6e-120 S CAAX protease self-immunity
NPKDGBBO_00155 2.9e-196 S DUF218 domain
NPKDGBBO_00156 1.2e-12 macB_3 V ABC transporter, ATP-binding protein
NPKDGBBO_00157 4.7e-45 macB_3 V ABC transporter, ATP-binding protein
NPKDGBBO_00158 0.0 macB_3 V ABC transporter, ATP-binding protein
NPKDGBBO_00159 4.3e-96 S ECF transporter, substrate-specific component
NPKDGBBO_00160 5.2e-161 yeaE S Aldo/keto reductase family
NPKDGBBO_00161 1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPKDGBBO_00162 1.8e-18
NPKDGBBO_00163 2.5e-64 XK27_01125 L IS66 Orf2 like protein
NPKDGBBO_00164 5.8e-32 S Transposase C of IS166 homeodomain
NPKDGBBO_00165 1.4e-261 L Transposase IS66 family
NPKDGBBO_00166 3e-37
NPKDGBBO_00167 6.4e-58 malY 4.4.1.8 E Aminotransferase, class I
NPKDGBBO_00168 1.4e-89 malY 4.4.1.8 E Aminotransferase, class I
NPKDGBBO_00169 1.8e-56
NPKDGBBO_00170 3.3e-245 brnQ U Component of the transport system for branched-chain amino acids
NPKDGBBO_00171 1.6e-35 L Transposase
NPKDGBBO_00172 1.1e-25 L Transposase
NPKDGBBO_00173 4.1e-26
NPKDGBBO_00174 9.4e-40 ptsH G phosphocarrier protein HPR
NPKDGBBO_00175 7.1e-306 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPKDGBBO_00176 3e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPKDGBBO_00177 5.7e-135 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NPKDGBBO_00178 5e-159 coiA 3.6.4.12 S Competence protein
NPKDGBBO_00179 3.3e-112 yjbH Q Thioredoxin
NPKDGBBO_00180 6.6e-113 yjbK S CYTH
NPKDGBBO_00181 2.1e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
NPKDGBBO_00182 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPKDGBBO_00183 1.9e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPKDGBBO_00184 9.9e-58 mycA 4.2.1.53 S Myosin-crossreactive antigen
NPKDGBBO_00185 1.3e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NPKDGBBO_00186 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
NPKDGBBO_00187 7.9e-274 E Amino acid permease
NPKDGBBO_00188 2e-43 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPKDGBBO_00189 8e-143 S Membrane protein involved in the export of O-antigen and teichoic acid
NPKDGBBO_00190 9.5e-66 M Glycosyltransferase like family 2
NPKDGBBO_00191 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NPKDGBBO_00192 2e-160 rssA S Phospholipase, patatin family
NPKDGBBO_00193 9.1e-150 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NPKDGBBO_00194 4e-116 dedA S SNARE-like domain protein
NPKDGBBO_00195 9.2e-83 S Protein of unknown function (DUF1461)
NPKDGBBO_00196 6.3e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPKDGBBO_00197 1.8e-89 yutD S Protein of unknown function (DUF1027)
NPKDGBBO_00198 1.5e-277 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NPKDGBBO_00199 5.6e-55
NPKDGBBO_00200 2.6e-263 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NPKDGBBO_00201 6.4e-182 ccpA K catabolite control protein A
NPKDGBBO_00202 1.2e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NPKDGBBO_00203 4.5e-54
NPKDGBBO_00204 6e-54 L An automated process has identified a potential problem with this gene model
NPKDGBBO_00205 3.5e-43 oppA E ABC transporter
NPKDGBBO_00206 4.3e-63 oppA E ABC transporter
NPKDGBBO_00207 1.7e-96 Q Imidazolonepropionase and related amidohydrolases
NPKDGBBO_00208 1.5e-74 Q Imidazolonepropionase and related amidohydrolases
NPKDGBBO_00209 3.7e-18 psiE S Phosphate-starvation-inducible E
NPKDGBBO_00211 1.9e-222 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPKDGBBO_00212 6.7e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NPKDGBBO_00213 7e-197 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NPKDGBBO_00214 9.2e-78 S SLAP domain
NPKDGBBO_00215 2.2e-113 S SLAP domain
NPKDGBBO_00216 1.1e-33 L An automated process has identified a potential problem with this gene model
NPKDGBBO_00217 9.2e-46 L An automated process has identified a potential problem with this gene model
NPKDGBBO_00218 1.8e-35 K response regulator
NPKDGBBO_00219 6.1e-63 sptS 2.7.13.3 T Histidine kinase
NPKDGBBO_00220 7.1e-117 sptS 2.7.13.3 T Histidine kinase
NPKDGBBO_00221 7.2e-209 EGP Major facilitator Superfamily
NPKDGBBO_00222 4e-13 O OsmC-like protein
NPKDGBBO_00223 3e-37 O OsmC-like protein
NPKDGBBO_00224 4.2e-127 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
NPKDGBBO_00225 1.2e-225 V ABC transporter transmembrane region
NPKDGBBO_00226 3.2e-118 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NPKDGBBO_00230 1.2e-194 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPKDGBBO_00231 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPKDGBBO_00232 2.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPKDGBBO_00233 6e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NPKDGBBO_00234 2.5e-308 recN L May be involved in recombinational repair of damaged DNA
NPKDGBBO_00235 3.5e-21 6.3.3.2 S ASCH
NPKDGBBO_00236 8.1e-44 6.3.3.2 S ASCH
NPKDGBBO_00237 1.9e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
NPKDGBBO_00238 6.5e-34 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NPKDGBBO_00239 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPKDGBBO_00240 2.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPKDGBBO_00241 5.8e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPKDGBBO_00242 2.4e-147 stp 3.1.3.16 T phosphatase
NPKDGBBO_00243 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NPKDGBBO_00244 2.6e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPKDGBBO_00245 3.8e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NPKDGBBO_00246 1.4e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
NPKDGBBO_00247 1.6e-51
NPKDGBBO_00248 1.1e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NPKDGBBO_00249 4.5e-35 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPKDGBBO_00250 1.9e-175 V ABC transporter transmembrane region
NPKDGBBO_00251 3.7e-42 KLT serine threonine protein kinase
NPKDGBBO_00252 1.3e-158 KLT Protein kinase domain
NPKDGBBO_00253 6.1e-274 P Sodium:sulfate symporter transmembrane region
NPKDGBBO_00254 4e-155 ydjP I Alpha/beta hydrolase family
NPKDGBBO_00255 3.3e-197 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NPKDGBBO_00256 9.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
NPKDGBBO_00257 8.2e-168 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
NPKDGBBO_00258 2.4e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NPKDGBBO_00259 2.7e-103
NPKDGBBO_00260 1.4e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
NPKDGBBO_00261 1.8e-51 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPKDGBBO_00262 5.2e-90 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPKDGBBO_00263 6.9e-84 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPKDGBBO_00264 5.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NPKDGBBO_00266 1.9e-132 cobQ S glutamine amidotransferase
NPKDGBBO_00267 7.2e-247 3.5.1.47 S Peptidase dimerisation domain
NPKDGBBO_00268 1.4e-139 S Protein of unknown function (DUF3100)
NPKDGBBO_00269 9.7e-83 S An automated process has identified a potential problem with this gene model
NPKDGBBO_00270 1.1e-24
NPKDGBBO_00271 1.2e-30 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
NPKDGBBO_00272 2.6e-80 yobV1 K WYL domain
NPKDGBBO_00273 5.8e-20 yobV1 K WYL domain
NPKDGBBO_00274 6.3e-44 S pyridoxamine 5-phosphate
NPKDGBBO_00275 9.4e-261 npr 1.11.1.1 C NADH oxidase
NPKDGBBO_00276 2.1e-121 K Transcriptional regulator
NPKDGBBO_00277 1.5e-58 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NPKDGBBO_00278 2.1e-64 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
NPKDGBBO_00279 6.5e-304 XK27_11280 S Psort location CytoplasmicMembrane, score
NPKDGBBO_00280 9.7e-183 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPKDGBBO_00281 8.6e-13 pepO 3.4.24.71 O Peptidase family M13
NPKDGBBO_00282 0.0 pepO 3.4.24.71 O Peptidase family M13
NPKDGBBO_00283 6.9e-71 S Enterocin A Immunity
NPKDGBBO_00284 4.1e-115 S Archaea bacterial proteins of unknown function
NPKDGBBO_00285 4.2e-146 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NPKDGBBO_00286 3.2e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPKDGBBO_00287 1.4e-209 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
NPKDGBBO_00288 5.1e-122 K response regulator
NPKDGBBO_00289 0.0 V ABC transporter
NPKDGBBO_00290 5.8e-308 V ABC transporter, ATP-binding protein
NPKDGBBO_00291 8.9e-139 XK27_01040 S Protein of unknown function (DUF1129)
NPKDGBBO_00292 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPKDGBBO_00293 2.1e-44 yyzM S Bacterial protein of unknown function (DUF951)
NPKDGBBO_00294 2.9e-154 spo0J K Belongs to the ParB family
NPKDGBBO_00295 3.4e-138 soj D Sporulation initiation inhibitor
NPKDGBBO_00296 1.6e-149 noc K Belongs to the ParB family
NPKDGBBO_00297 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NPKDGBBO_00298 6.6e-85 cvpA S Colicin V production protein
NPKDGBBO_00299 1.7e-181 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NPKDGBBO_00300 6.7e-150 3.1.3.48 T Tyrosine phosphatase family
NPKDGBBO_00301 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
NPKDGBBO_00302 2e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
NPKDGBBO_00303 5.7e-112 K WHG domain
NPKDGBBO_00304 2e-103
NPKDGBBO_00305 2.1e-26
NPKDGBBO_00306 1.6e-79
NPKDGBBO_00307 1.2e-24 S Protein of unknown function (DUF554)
NPKDGBBO_00308 2.4e-215 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NPKDGBBO_00309 0.0 pepF E oligoendopeptidase F
NPKDGBBO_00310 1.5e-09 Z012_06740 S Fic/DOC family
NPKDGBBO_00311 1.7e-34 D Filamentation induced by cAMP protein fic
NPKDGBBO_00312 2.1e-42 S Enterocin A Immunity
NPKDGBBO_00313 3e-51 lctP C L-lactate permease
NPKDGBBO_00314 6.1e-90 lctP C L-lactate permease
NPKDGBBO_00315 7.5e-23 lctP C L-lactate permease
NPKDGBBO_00318 9.4e-142 2.7.1.89 M Phosphotransferase enzyme family
NPKDGBBO_00319 2.2e-77
NPKDGBBO_00321 8.9e-70 gntR K UbiC transcription regulator-associated domain protein
NPKDGBBO_00322 7.6e-21 gntR K UbiC transcription regulator-associated domain protein
NPKDGBBO_00323 4.8e-176 rihB 3.2.2.1 F Nucleoside
NPKDGBBO_00324 0.0 kup P Transport of potassium into the cell
NPKDGBBO_00325 2e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NPKDGBBO_00326 1.2e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPKDGBBO_00327 1.6e-162 2.7.7.12 C Domain of unknown function (DUF4931)
NPKDGBBO_00328 1.7e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NPKDGBBO_00329 3.6e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NPKDGBBO_00330 1.4e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NPKDGBBO_00331 2.2e-176 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NPKDGBBO_00332 2.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NPKDGBBO_00333 7.1e-217 aspC 2.6.1.1 E Aminotransferase
NPKDGBBO_00334 1.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NPKDGBBO_00335 1.8e-28 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NPKDGBBO_00336 8.6e-105 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NPKDGBBO_00337 2.2e-93 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NPKDGBBO_00338 7.7e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NPKDGBBO_00339 6.4e-37
NPKDGBBO_00340 5.2e-133 4.1.1.44 S Carboxymuconolactone decarboxylase family
NPKDGBBO_00341 5.2e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPKDGBBO_00342 2.4e-50 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPKDGBBO_00345 7.4e-140 M NlpC/P60 family
NPKDGBBO_00346 8.7e-15 S Fic/DOC family
NPKDGBBO_00347 2.3e-243 L Probable transposase
NPKDGBBO_00348 1.7e-32 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPKDGBBO_00349 5.3e-43
NPKDGBBO_00350 2.6e-46 K Helix-turn-helix XRE-family like proteins
NPKDGBBO_00351 5.9e-29 yitS S Uncharacterised protein, DegV family COG1307
NPKDGBBO_00352 1.1e-92 yitS S Uncharacterised protein, DegV family COG1307
NPKDGBBO_00353 4.7e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPKDGBBO_00354 7.5e-69 S Domain of unknown function (DUF4767)
NPKDGBBO_00355 1.2e-85 C nitroreductase
NPKDGBBO_00356 7.7e-11 ypbG 2.7.1.2 GK ROK family
NPKDGBBO_00357 7.7e-80 ypbG 2.7.1.2 GK ROK family
NPKDGBBO_00358 2.8e-281 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPKDGBBO_00359 1.1e-135 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPKDGBBO_00360 1.2e-18
NPKDGBBO_00361 6.1e-40 V ABC transporter transmembrane region
NPKDGBBO_00362 3.8e-94 V ABC transporter transmembrane region
NPKDGBBO_00364 1.4e-190 tcsA S ABC transporter substrate-binding protein PnrA-like
NPKDGBBO_00365 3.6e-285 xylG 3.6.3.17 S ABC transporter
NPKDGBBO_00366 1e-199 yufP S Belongs to the binding-protein-dependent transport system permease family
NPKDGBBO_00367 4.7e-166 yufQ S Belongs to the binding-protein-dependent transport system permease family
NPKDGBBO_00368 8.4e-143 K SIS domain
NPKDGBBO_00369 1e-31 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
NPKDGBBO_00370 3.4e-49 pspC KT PspC domain
NPKDGBBO_00372 2.2e-243 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NPKDGBBO_00373 4.3e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPKDGBBO_00374 1.5e-110 M ErfK YbiS YcfS YnhG
NPKDGBBO_00375 5.2e-78 padR K Virulence activator alpha C-term
NPKDGBBO_00376 2.2e-104 padC Q Phenolic acid decarboxylase
NPKDGBBO_00377 3.9e-113 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPKDGBBO_00379 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NPKDGBBO_00380 9.6e-68 S Protein of unknown function (DUF3290)
NPKDGBBO_00381 2e-140 pnuC H nicotinamide mononucleotide transporter
NPKDGBBO_00382 2.4e-11
NPKDGBBO_00383 2.9e-277 V ABC transporter transmembrane region
NPKDGBBO_00384 9.3e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NPKDGBBO_00385 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NPKDGBBO_00386 1.3e-95 F Nucleoside 2-deoxyribosyltransferase
NPKDGBBO_00388 2.8e-67 S Peptidase propeptide and YPEB domain
NPKDGBBO_00389 1.4e-217 G Bacterial extracellular solute-binding protein
NPKDGBBO_00390 5.8e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPKDGBBO_00391 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
NPKDGBBO_00392 6.6e-31 K Helix-turn-helix XRE-family like proteins
NPKDGBBO_00393 1.5e-91 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPKDGBBO_00394 2e-180 htrA 3.4.21.107 O serine protease
NPKDGBBO_00395 3.3e-149 vicX 3.1.26.11 S domain protein
NPKDGBBO_00396 6.9e-150 yycI S YycH protein
NPKDGBBO_00397 1.2e-244 yycH S YycH protein
NPKDGBBO_00398 3.7e-308 vicK 2.7.13.3 T Histidine kinase
NPKDGBBO_00399 1.1e-130 K response regulator
NPKDGBBO_00401 2.4e-33
NPKDGBBO_00403 6.7e-11 L Transposase
NPKDGBBO_00404 2e-166 S SLAP domain
NPKDGBBO_00405 1.1e-104
NPKDGBBO_00406 5.3e-07 S ParE toxin of type II toxin-antitoxin system, parDE
NPKDGBBO_00407 1e-116 mta K helix_turn_helix, mercury resistance
NPKDGBBO_00408 1.1e-92 yyaR K Acetyltransferase (GNAT) domain
NPKDGBBO_00409 0.0 uvrA3 L excinuclease ABC, A subunit
NPKDGBBO_00411 1.7e-82 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
NPKDGBBO_00413 8.8e-178 psaA P Belongs to the bacterial solute-binding protein 9 family
NPKDGBBO_00416 1.1e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPKDGBBO_00417 5.7e-256 qacA EGP Major facilitator Superfamily
NPKDGBBO_00418 6.8e-66 2.1.1.113, 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NPKDGBBO_00420 6.2e-22
NPKDGBBO_00421 6.1e-170 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NPKDGBBO_00422 9.4e-68 yslB S Protein of unknown function (DUF2507)
NPKDGBBO_00423 1.8e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NPKDGBBO_00424 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPKDGBBO_00425 3.7e-146 L Transposase
NPKDGBBO_00426 3e-135 ycaM E amino acid
NPKDGBBO_00427 4.4e-59 ycaM E amino acid
NPKDGBBO_00428 6.6e-153 S haloacid dehalogenase-like hydrolase
NPKDGBBO_00429 0.0 S SH3-like domain
NPKDGBBO_00430 7.1e-207 G Major Facilitator Superfamily
NPKDGBBO_00431 7.6e-135 aroF 2.5.1.54 E DAHP synthetase I family
NPKDGBBO_00432 3.4e-133 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NPKDGBBO_00435 3.9e-114 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NPKDGBBO_00436 4.5e-50 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NPKDGBBO_00438 1.3e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPKDGBBO_00439 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NPKDGBBO_00440 1.2e-55 yheA S Belongs to the UPF0342 family
NPKDGBBO_00441 1.8e-231 yhaO L Ser Thr phosphatase family protein
NPKDGBBO_00442 0.0 L AAA domain
NPKDGBBO_00443 6.4e-187 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPKDGBBO_00444 1.6e-51 S PAS domain
NPKDGBBO_00446 7.9e-148 L transposase, IS605 OrfB family
NPKDGBBO_00447 6e-17 D nuclear chromosome segregation
NPKDGBBO_00448 2.6e-40 srtA 3.4.22.70 M sortase family
NPKDGBBO_00449 2e-299 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NPKDGBBO_00450 1.3e-81 C Flavodoxin
NPKDGBBO_00451 1.3e-111 3.6.1.27 I Acid phosphatase homologues
NPKDGBBO_00452 1e-105 lacA 2.3.1.79 S Transferase hexapeptide repeat
NPKDGBBO_00453 6.3e-207 pbpX1 V Beta-lactamase
NPKDGBBO_00454 4.5e-109 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NPKDGBBO_00455 3.6e-20 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NPKDGBBO_00456 6.9e-93 S ECF-type riboflavin transporter, S component
NPKDGBBO_00457 8.1e-232 S Putative peptidoglycan binding domain
NPKDGBBO_00458 1.4e-188 mepA V MATE efflux family protein
NPKDGBBO_00459 1e-256 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NPKDGBBO_00460 2.2e-34
NPKDGBBO_00461 9.7e-61
NPKDGBBO_00462 8.3e-91
NPKDGBBO_00463 1.7e-57
NPKDGBBO_00464 2.1e-108 S Fic/DOC family
NPKDGBBO_00465 5.9e-103
NPKDGBBO_00466 6.1e-208 EGP Major facilitator Superfamily
NPKDGBBO_00467 1.6e-134
NPKDGBBO_00468 4.3e-56
NPKDGBBO_00469 9.4e-80 K Acetyltransferase (GNAT) domain
NPKDGBBO_00471 1.8e-65 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
NPKDGBBO_00472 6.2e-145 2.4.2.3 F Phosphorylase superfamily
NPKDGBBO_00473 4.3e-120 XK27_07525 3.6.1.55 F NUDIX domain
NPKDGBBO_00475 1.3e-63
NPKDGBBO_00476 2.6e-83 S Domain of unknown function (DUF5067)
NPKDGBBO_00477 3.7e-76 L COG2963 Transposase and inactivated derivatives
NPKDGBBO_00478 1.8e-50 L An automated process has identified a potential problem with this gene model
NPKDGBBO_00479 6e-154 S hydrolase
NPKDGBBO_00480 4.8e-38 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
NPKDGBBO_00481 7.9e-130 S YSIRK type signal peptide
NPKDGBBO_00482 6.2e-13 M domain protein
NPKDGBBO_00483 6.3e-08 M domain protein
NPKDGBBO_00484 1.5e-57 M domain protein
NPKDGBBO_00486 3.9e-262 frdC 1.3.5.4 C FAD binding domain
NPKDGBBO_00487 4.5e-266 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPKDGBBO_00488 1.7e-34
NPKDGBBO_00489 6.3e-62 S cog cog1373
NPKDGBBO_00490 1.3e-76 S cog cog1373
NPKDGBBO_00491 6.4e-88 metI P ABC transporter permease
NPKDGBBO_00492 3.6e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPKDGBBO_00493 2.8e-162 metQ1 P Belongs to the nlpA lipoprotein family
NPKDGBBO_00494 0.0 aha1 P E1-E2 ATPase
NPKDGBBO_00495 1.5e-109 K Transcriptional regulator, LysR family
NPKDGBBO_00496 1.3e-34 S Cytochrome b5
NPKDGBBO_00497 1.7e-167 arbZ I Phosphate acyltransferases
NPKDGBBO_00498 1.7e-150 arbY M Glycosyl transferase family 8
NPKDGBBO_00499 3.7e-10 arbY M Glycosyl transferase family 8
NPKDGBBO_00500 1.8e-186 arbY M Glycosyl transferase family 8
NPKDGBBO_00501 4.1e-158 arbx M Glycosyl transferase family 8
NPKDGBBO_00502 4e-13 K Helix-turn-helix domain
NPKDGBBO_00503 1.3e-87 K Helix-turn-helix domain
NPKDGBBO_00504 1.9e-14
NPKDGBBO_00505 4.5e-67
NPKDGBBO_00506 6.6e-147 arbV 2.3.1.51 I Acyl-transferase
NPKDGBBO_00507 2.7e-197 S SLAP domain
NPKDGBBO_00508 3.9e-18
NPKDGBBO_00509 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPKDGBBO_00510 8.3e-108 vanZ V VanZ like family
NPKDGBBO_00511 6.4e-262 pgi 5.3.1.9 G Belongs to the GPI family
NPKDGBBO_00512 7.7e-119 EGP Major facilitator Superfamily
NPKDGBBO_00513 3.3e-133 mdlA V ABC transporter
NPKDGBBO_00514 3.1e-164 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPKDGBBO_00515 4.7e-96 ywnH 2.3.1.183 M acetyltransferase (GNAT) family
NPKDGBBO_00516 2.2e-15 K Penicillinase repressor
NPKDGBBO_00517 0.0 copB 3.6.3.4 P P-type ATPase
NPKDGBBO_00518 2.7e-39 mdt(A) EGP Major facilitator Superfamily
NPKDGBBO_00519 1.7e-66 mdt(A) EGP Major facilitator Superfamily
NPKDGBBO_00520 2.1e-241 amtB P ammonium transporter
NPKDGBBO_00521 7.5e-82 V Abi-like protein
NPKDGBBO_00522 1.1e-06 L the current gene model (or a revised gene model) may contain a
NPKDGBBO_00523 1.8e-231 S Uncharacterised protein family (UPF0236)
NPKDGBBO_00524 9.1e-61 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPKDGBBO_00525 5.5e-135 gmuR K UTRA
NPKDGBBO_00526 1.6e-121 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPKDGBBO_00527 4.6e-91 S VanZ like family
NPKDGBBO_00528 8.9e-133 yebC K Transcriptional regulatory protein
NPKDGBBO_00529 8.4e-179 comGA NU Type II IV secretion system protein
NPKDGBBO_00530 9e-176 comGB NU type II secretion system
NPKDGBBO_00531 3.7e-44 comGC U competence protein ComGC
NPKDGBBO_00532 2.1e-73
NPKDGBBO_00533 5.6e-40
NPKDGBBO_00534 8.9e-84 comGF U Putative Competence protein ComGF
NPKDGBBO_00535 8.6e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
NPKDGBBO_00536 7.2e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPKDGBBO_00538 1.6e-25
NPKDGBBO_00539 7.4e-25
NPKDGBBO_00541 4.2e-34
NPKDGBBO_00545 4.8e-32
NPKDGBBO_00546 3.6e-15
NPKDGBBO_00547 4e-13 K transcriptional
NPKDGBBO_00548 4.1e-140 sip L Belongs to the 'phage' integrase family
NPKDGBBO_00549 7.9e-34 M Protein of unknown function (DUF3737)
NPKDGBBO_00550 1.1e-31 M Protein of unknown function (DUF3737)
NPKDGBBO_00551 1.1e-129 patB 4.4.1.8 E Aminotransferase, class I
NPKDGBBO_00552 5e-72 patB 4.4.1.8 E Aminotransferase, class I
NPKDGBBO_00553 1.7e-168 manA 5.3.1.8 G mannose-6-phosphate isomerase
NPKDGBBO_00554 8.3e-61 S SdpI/YhfL protein family
NPKDGBBO_00555 8.3e-131 K Transcriptional regulatory protein, C terminal
NPKDGBBO_00556 2.8e-271 yclK 2.7.13.3 T Histidine kinase
NPKDGBBO_00557 3.5e-47 oppA E ABC transporter
NPKDGBBO_00558 1.8e-76 oppA E ABC transporter
NPKDGBBO_00559 1.2e-67 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
NPKDGBBO_00560 3.1e-275 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
NPKDGBBO_00561 6.1e-219 naiP EGP Major facilitator Superfamily
NPKDGBBO_00562 2.1e-224 patA 2.6.1.1 E Aminotransferase
NPKDGBBO_00563 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NPKDGBBO_00564 2.3e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NPKDGBBO_00565 2.1e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPKDGBBO_00566 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPKDGBBO_00567 8.5e-60
NPKDGBBO_00568 1.2e-174 prmA J Ribosomal protein L11 methyltransferase
NPKDGBBO_00569 3.3e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NPKDGBBO_00572 4e-34 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPKDGBBO_00573 9.3e-152 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NPKDGBBO_00574 1.7e-229 mtnE 2.6.1.83 E Aminotransferase
NPKDGBBO_00575 3.8e-184 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPKDGBBO_00576 7.4e-146 ywqE 3.1.3.48 GM PHP domain protein
NPKDGBBO_00577 6.7e-118 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NPKDGBBO_00578 2.3e-143 epsB M biosynthesis protein
NPKDGBBO_00579 4.1e-179 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NPKDGBBO_00580 2.7e-201 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NPKDGBBO_00581 1.7e-133 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NPKDGBBO_00582 1.7e-229 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
NPKDGBBO_00583 9e-112 G Phosphoglycerate mutase family
NPKDGBBO_00584 1.7e-196 D nuclear chromosome segregation
NPKDGBBO_00585 2.5e-68 M LysM domain protein
NPKDGBBO_00586 5.6e-13
NPKDGBBO_00587 7.9e-17 L COG2963 Transposase and inactivated derivatives
NPKDGBBO_00588 1.2e-32 S Uncharacterised protein family (UPF0236)
NPKDGBBO_00589 5.8e-116 S Uncharacterised protein family (UPF0236)
NPKDGBBO_00590 3.4e-106 soj D AAA domain
NPKDGBBO_00591 1.3e-28
NPKDGBBO_00592 1.8e-22 stp_1 EGP Major facilitator Superfamily
NPKDGBBO_00593 5e-102 tnpR L Resolvase, N terminal domain
NPKDGBBO_00594 3.6e-148 2.1.1.72 L DNA methylase
NPKDGBBO_00595 1.2e-64 res 3.1.21.5 L Type III restriction enzyme, res subunit
NPKDGBBO_00596 4.7e-63 yodB K Transcriptional regulator, HxlR family
NPKDGBBO_00597 4e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPKDGBBO_00598 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPKDGBBO_00599 1.4e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPKDGBBO_00600 8.7e-170 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
NPKDGBBO_00601 2.9e-57 S Phage derived protein Gp49-like (DUF891)
NPKDGBBO_00602 1.3e-36 K Helix-turn-helix domain
NPKDGBBO_00603 5.9e-81 S Short repeat of unknown function (DUF308)
NPKDGBBO_00604 4.8e-165 rapZ S Displays ATPase and GTPase activities
NPKDGBBO_00605 2.6e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NPKDGBBO_00606 1.4e-170 whiA K May be required for sporulation
NPKDGBBO_00607 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPKDGBBO_00609 3.1e-16 S Peptidase propeptide and YPEB domain
NPKDGBBO_00610 4.4e-64 G Glycosyl hydrolases family 8
NPKDGBBO_00611 2e-23 G Glycosyl hydrolases family 8
NPKDGBBO_00612 1.9e-29 L COG2963 Transposase and inactivated derivatives
NPKDGBBO_00613 1.8e-206 pbpX1 V Beta-lactamase
NPKDGBBO_00614 2.1e-105 3.6.1.55 F NUDIX domain
NPKDGBBO_00615 4.5e-302 I Protein of unknown function (DUF2974)
NPKDGBBO_00616 2.3e-17 C FMN_bind
NPKDGBBO_00617 1e-82
NPKDGBBO_00618 3.8e-173 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
NPKDGBBO_00619 1.5e-174 S Aldo keto reductase
NPKDGBBO_00620 5e-62 L COG2826 Transposase and inactivated derivatives, IS30 family
NPKDGBBO_00621 1.1e-32 cpsJ S Glycosyltransferase like family 2
NPKDGBBO_00622 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPKDGBBO_00623 1.2e-238 nfrB 2.4.1.336 GT2 M Glycosyltransferase like family 2
NPKDGBBO_00625 4.6e-33 EGP Major facilitator Superfamily
NPKDGBBO_00626 3.1e-147 L Probable transposase
NPKDGBBO_00627 7.5e-15 NU Mycoplasma protein of unknown function, DUF285
NPKDGBBO_00628 4.8e-81 S Domain of unknown function (DUF4430)
NPKDGBBO_00629 9.3e-184 U FFAT motif binding
NPKDGBBO_00630 2.3e-297 S Domain of unknown function (DUF4430)
NPKDGBBO_00631 1.7e-176 S Uncharacterised protein family (UPF0236)
NPKDGBBO_00632 2.5e-62 3.6.1.27 I Acid phosphatase homologues
NPKDGBBO_00633 3.3e-116 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPKDGBBO_00635 6.7e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPKDGBBO_00636 8.1e-96 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPKDGBBO_00637 7.2e-16 ps301 K sequence-specific DNA binding
NPKDGBBO_00638 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPKDGBBO_00639 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NPKDGBBO_00640 3.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPKDGBBO_00641 3.2e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPKDGBBO_00642 1.3e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPKDGBBO_00643 7.5e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NPKDGBBO_00644 3.6e-14 yjeM E Amino Acid
NPKDGBBO_00645 5.9e-183 yjeM E Amino Acid
NPKDGBBO_00646 1.5e-191 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NPKDGBBO_00647 8.3e-265 lysC 2.7.2.4 E Belongs to the aspartokinase family
NPKDGBBO_00649 1.6e-60 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
NPKDGBBO_00650 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NPKDGBBO_00651 7.4e-68
NPKDGBBO_00652 4.5e-50
NPKDGBBO_00653 1e-211 mdtG EGP Major facilitator Superfamily
NPKDGBBO_00654 1.5e-172
NPKDGBBO_00655 1.2e-58 lysM M LysM domain
NPKDGBBO_00657 0.0 pepN 3.4.11.2 E aminopeptidase
NPKDGBBO_00658 7.6e-248 dtpT U amino acid peptide transporter
NPKDGBBO_00659 1.8e-24
NPKDGBBO_00660 1.6e-182 S Putative peptidoglycan binding domain
NPKDGBBO_00661 3.8e-40 L transposase, IS605 OrfB family
NPKDGBBO_00662 3.3e-10 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NPKDGBBO_00663 1.3e-248 N Uncharacterized conserved protein (DUF2075)
NPKDGBBO_00664 2.1e-34 mmuP E amino acid
NPKDGBBO_00665 7.2e-130 mmuP E amino acid
NPKDGBBO_00666 1.8e-30 mmuP E amino acid
NPKDGBBO_00667 4.2e-36 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NPKDGBBO_00668 1.6e-25 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NPKDGBBO_00669 5.6e-49 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NPKDGBBO_00670 4.7e-232 amd 3.5.1.47 E Peptidase family M20/M25/M40
NPKDGBBO_00671 2.5e-234 steT E amino acid
NPKDGBBO_00672 2.7e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
NPKDGBBO_00673 3.7e-66 S ASCH domain
NPKDGBBO_00674 1.8e-167 L restriction endonuclease
NPKDGBBO_00675 1.9e-155 L helicase
NPKDGBBO_00676 1.2e-149 hsdM 2.1.1.72 V type I restriction-modification system
NPKDGBBO_00677 6.3e-204 3.1.21.3 V Type I restriction modification DNA specificity domain
NPKDGBBO_00678 2.3e-156 hsdM 2.1.1.72 V type I restriction-modification system
NPKDGBBO_00679 3.9e-46 L COG2963 Transposase and inactivated derivatives
NPKDGBBO_00680 5.3e-57 L COG2963 Transposase and inactivated derivatives
NPKDGBBO_00681 4e-52 L COG2963 Transposase and inactivated derivatives
NPKDGBBO_00682 5.8e-297 ytgP S Polysaccharide biosynthesis protein
NPKDGBBO_00683 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPKDGBBO_00684 1.3e-119 3.6.1.27 I Acid phosphatase homologues
NPKDGBBO_00685 6.2e-43 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPKDGBBO_00686 1.4e-71 S Iron-sulphur cluster biosynthesis
NPKDGBBO_00687 7.1e-32
NPKDGBBO_00688 5.4e-68
NPKDGBBO_00689 3.9e-29 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
NPKDGBBO_00690 1.6e-48 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
NPKDGBBO_00691 2.7e-21 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
NPKDGBBO_00692 5.7e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPKDGBBO_00693 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NPKDGBBO_00694 1.5e-123 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
NPKDGBBO_00695 2.8e-108 L Transposase and inactivated derivatives, IS30 family
NPKDGBBO_00696 9.8e-181 P secondary active sulfate transmembrane transporter activity
NPKDGBBO_00697 2.3e-96 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
NPKDGBBO_00698 3.5e-106 K LysR substrate binding domain
NPKDGBBO_00699 1.1e-19
NPKDGBBO_00700 2.5e-214 S Sterol carrier protein domain
NPKDGBBO_00701 8.9e-98 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NPKDGBBO_00702 2.8e-52 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NPKDGBBO_00703 1.9e-66 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NPKDGBBO_00704 6.8e-110 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NPKDGBBO_00705 3.9e-13 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NPKDGBBO_00706 4.9e-44 arcA 3.5.3.6 E Arginine
NPKDGBBO_00707 9e-58 arcA 3.5.3.6 E Arginine
NPKDGBBO_00708 3.2e-26 arcA 3.5.3.6 E Arginine
NPKDGBBO_00709 1e-113 lysR5 K LysR substrate binding domain
NPKDGBBO_00710 1.3e-29 lysR5 K LysR substrate binding domain
NPKDGBBO_00711 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
NPKDGBBO_00712 1.6e-85 3.4.21.96 S SLAP domain
NPKDGBBO_00713 2e-68 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPKDGBBO_00714 1.2e-112 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPKDGBBO_00715 4.2e-152 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NPKDGBBO_00716 8e-171 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NPKDGBBO_00717 3.7e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPKDGBBO_00718 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NPKDGBBO_00719 2.1e-120 srtA 3.4.22.70 M sortase family
NPKDGBBO_00720 8.5e-142 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPKDGBBO_00721 2.6e-186 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPKDGBBO_00722 3.8e-15
NPKDGBBO_00723 3.6e-25 L An automated process has identified a potential problem with this gene model
NPKDGBBO_00724 2.2e-54 S Protein of unknown function (DUF3397)
NPKDGBBO_00725 6.5e-13 S Protein of unknown function (DUF4044)
NPKDGBBO_00726 3.8e-96 mreD
NPKDGBBO_00727 7.9e-149 mreC M Involved in formation and maintenance of cell shape
NPKDGBBO_00728 4.9e-174 mreB D cell shape determining protein MreB
NPKDGBBO_00729 2.1e-114 radC L DNA repair protein
NPKDGBBO_00730 5.7e-126 S Haloacid dehalogenase-like hydrolase
NPKDGBBO_00731 7.2e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NPKDGBBO_00732 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPKDGBBO_00733 1.8e-39
NPKDGBBO_00735 4.1e-118 K UTRA domain
NPKDGBBO_00736 1.8e-59 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPKDGBBO_00737 3.6e-182 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPKDGBBO_00738 9.8e-18 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPKDGBBO_00739 2.4e-51 K Putative DNA-binding domain
NPKDGBBO_00740 3.9e-166 S Uncharacterised protein family (UPF0236)
NPKDGBBO_00741 1.9e-42 L transposase, IS605 OrfB family
NPKDGBBO_00742 1.5e-48 UW LPXTG-motif cell wall anchor domain protein
NPKDGBBO_00743 2.6e-78 UW LPXTG-motif cell wall anchor domain protein
NPKDGBBO_00744 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPKDGBBO_00745 3.7e-74 fhaB M Rib/alpha-like repeat
NPKDGBBO_00746 1.5e-12
NPKDGBBO_00747 4.7e-20
NPKDGBBO_00749 9.3e-29
NPKDGBBO_00750 1.9e-258 pepC 3.4.22.40 E Peptidase C1-like family
NPKDGBBO_00751 1.9e-96 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
NPKDGBBO_00752 3.3e-101 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
NPKDGBBO_00753 7.5e-108 pncA Q Isochorismatase family
NPKDGBBO_00754 1.2e-271 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPKDGBBO_00766 3.6e-151 xerD L Phage integrase, N-terminal SAM-like domain
NPKDGBBO_00767 8.4e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPKDGBBO_00768 2.9e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPKDGBBO_00769 1.9e-33 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPKDGBBO_00770 2.6e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPKDGBBO_00771 4.2e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
NPKDGBBO_00772 4.1e-153 ykuT M mechanosensitive ion channel
NPKDGBBO_00773 3.3e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPKDGBBO_00774 2e-43
NPKDGBBO_00776 8.5e-142 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NPKDGBBO_00777 3.1e-68
NPKDGBBO_00778 2.1e-20 hicB S protein encoded in hypervariable junctions of pilus gene clusters
NPKDGBBO_00779 4e-80 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NPKDGBBO_00780 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NPKDGBBO_00781 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPKDGBBO_00782 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NPKDGBBO_00783 8.9e-55 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NPKDGBBO_00784 3e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NPKDGBBO_00785 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
NPKDGBBO_00786 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPKDGBBO_00787 6e-73 nrdI F Probably involved in ribonucleotide reductase function
NPKDGBBO_00788 7.3e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPKDGBBO_00789 9.8e-18 IQ reductase
NPKDGBBO_00790 7.4e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
NPKDGBBO_00791 7e-220 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NPKDGBBO_00792 3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NPKDGBBO_00793 4.3e-23
NPKDGBBO_00794 3.6e-35 S Uncharacterised protein family (UPF0236)
NPKDGBBO_00796 5.6e-10
NPKDGBBO_00797 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPKDGBBO_00798 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPKDGBBO_00799 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NPKDGBBO_00800 2.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
NPKDGBBO_00802 1.6e-08
NPKDGBBO_00803 7.6e-80
NPKDGBBO_00805 2.4e-300 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NPKDGBBO_00806 4.7e-196 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPKDGBBO_00807 3.1e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPKDGBBO_00808 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPKDGBBO_00809 5.8e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPKDGBBO_00810 4.1e-62 yabR J S1 RNA binding domain
NPKDGBBO_00811 9.8e-59 divIC D Septum formation initiator
NPKDGBBO_00812 1.8e-34 yabO J S4 domain protein
NPKDGBBO_00813 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPKDGBBO_00814 1.7e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPKDGBBO_00815 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPKDGBBO_00816 2.2e-128 S (CBS) domain
NPKDGBBO_00817 9.7e-92 K transcriptional regulator
NPKDGBBO_00818 5.3e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPKDGBBO_00819 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPKDGBBO_00820 1.9e-254 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPKDGBBO_00821 5.9e-263 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPKDGBBO_00822 1.9e-39 rpmE2 J Ribosomal protein L31
NPKDGBBO_00823 9.1e-158 S Sucrose-6F-phosphate phosphohydrolase
NPKDGBBO_00824 5.9e-94 L An automated process has identified a potential problem with this gene model
NPKDGBBO_00825 3.1e-24 S Glycosyltransferase like family 2
NPKDGBBO_00826 1.5e-19 S EpsG family
NPKDGBBO_00827 3.1e-14 K Putative DNA-binding domain
NPKDGBBO_00828 1.1e-158 K Putative DNA-binding domain
NPKDGBBO_00829 1.3e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NPKDGBBO_00830 1.8e-139 fruR K DeoR C terminal sensor domain
NPKDGBBO_00833 8.7e-27
NPKDGBBO_00834 7.1e-33
NPKDGBBO_00835 1e-34 yozG K Transcriptional regulator
NPKDGBBO_00836 6.3e-193 L COG2826 Transposase and inactivated derivatives, IS30 family
NPKDGBBO_00837 1.1e-264 pepC 3.4.22.40 E Peptidase C1-like family
NPKDGBBO_00839 1.3e-128 XK27_08435 K UTRA
NPKDGBBO_00840 2.8e-229 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NPKDGBBO_00841 2e-29 cspA K Cold shock protein
NPKDGBBO_00844 1.7e-95 MA20_25245 K Acetyltransferase (GNAT) domain
NPKDGBBO_00845 2e-255 gor 1.8.1.7 C Glutathione reductase
NPKDGBBO_00846 1.8e-77 mraZ K Belongs to the MraZ family
NPKDGBBO_00847 1.5e-183 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPKDGBBO_00848 1.4e-54 ftsL D Cell division protein FtsL
NPKDGBBO_00849 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NPKDGBBO_00850 1.9e-47 ftsI 3.4.16.4 M Penicillin-binding Protein
NPKDGBBO_00851 7.1e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPKDGBBO_00852 4.3e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPKDGBBO_00853 1.8e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPKDGBBO_00854 3.8e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPKDGBBO_00855 2.6e-231 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPKDGBBO_00856 6.8e-208 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPKDGBBO_00857 1.3e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NPKDGBBO_00858 4.5e-46 yggT S YGGT family
NPKDGBBO_00859 3.3e-149 ylmH S S4 domain protein
NPKDGBBO_00860 2e-101 gpsB D DivIVA domain protein
NPKDGBBO_00861 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPKDGBBO_00862 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
NPKDGBBO_00863 7.5e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NPKDGBBO_00864 1.9e-39
NPKDGBBO_00865 2.9e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPKDGBBO_00866 2.4e-217 iscS 2.8.1.7 E Aminotransferase class V
NPKDGBBO_00867 1.4e-56 XK27_04120 S Putative amino acid metabolism
NPKDGBBO_00868 1.2e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPKDGBBO_00869 5.6e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NPKDGBBO_00870 1e-103 S Repeat protein
NPKDGBBO_00871 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPKDGBBO_00872 3.5e-106 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NPKDGBBO_00873 2.3e-29 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NPKDGBBO_00874 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPKDGBBO_00875 4.2e-33 ykzG S Belongs to the UPF0356 family
NPKDGBBO_00876 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPKDGBBO_00877 0.0 typA T GTP-binding protein TypA
NPKDGBBO_00878 4.7e-208 ftsW D Belongs to the SEDS family
NPKDGBBO_00879 8.7e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NPKDGBBO_00880 2.2e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NPKDGBBO_00881 2.7e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPKDGBBO_00882 5.4e-192 ylbL T Belongs to the peptidase S16 family
NPKDGBBO_00883 6.2e-83 comEA L Competence protein ComEA
NPKDGBBO_00884 0.0 comEC S Competence protein ComEC
NPKDGBBO_00885 4.8e-174 holA 2.7.7.7 L DNA polymerase III delta subunit
NPKDGBBO_00886 6.7e-35 rpsT J Binds directly to 16S ribosomal RNA
NPKDGBBO_00887 7e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPKDGBBO_00888 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPKDGBBO_00889 2.2e-151
NPKDGBBO_00890 1.4e-15 emrY EGP Major facilitator Superfamily
NPKDGBBO_00891 1e-29 emrY EGP Major facilitator Superfamily
NPKDGBBO_00896 5.2e-225 S response to antibiotic
NPKDGBBO_00897 6e-106 yoaK S Protein of unknown function (DUF1275)
NPKDGBBO_00898 7.7e-39 S Transglycosylase associated protein
NPKDGBBO_00899 5.9e-310 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
NPKDGBBO_00900 1.4e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
NPKDGBBO_00901 3.8e-190 oppA E ABC transporter, substratebinding protein
NPKDGBBO_00902 2.4e-83 S COG NOG38524 non supervised orthologous group
NPKDGBBO_00904 2.2e-122 yfbR S HD containing hydrolase-like enzyme
NPKDGBBO_00905 2.4e-161 L HNH nucleases
NPKDGBBO_00906 3.3e-138 glnQ E ABC transporter, ATP-binding protein
NPKDGBBO_00907 2.9e-293 glnP P ABC transporter permease
NPKDGBBO_00908 3.3e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NPKDGBBO_00909 8.2e-63 yeaO S Protein of unknown function, DUF488
NPKDGBBO_00910 3.8e-121 terC P Integral membrane protein TerC family
NPKDGBBO_00911 1.7e-93 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
NPKDGBBO_00912 4.3e-132 cobB K SIR2 family
NPKDGBBO_00913 1e-84
NPKDGBBO_00914 1.2e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPKDGBBO_00915 3.4e-177 S Alpha/beta hydrolase of unknown function (DUF915)
NPKDGBBO_00916 3.6e-145 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPKDGBBO_00917 2.2e-139 ypuA S Protein of unknown function (DUF1002)
NPKDGBBO_00918 1.2e-159 epsV 2.7.8.12 S glycosyl transferase family 2
NPKDGBBO_00919 2.5e-126 S Alpha/beta hydrolase family
NPKDGBBO_00920 1.3e-114 GM NmrA-like family
NPKDGBBO_00921 2.5e-55
NPKDGBBO_00922 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPKDGBBO_00923 1.7e-122 luxT K Bacterial regulatory proteins, tetR family
NPKDGBBO_00924 6.7e-129
NPKDGBBO_00925 2.9e-263 glnPH2 P ABC transporter permease
NPKDGBBO_00926 8.1e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPKDGBBO_00927 2.6e-166 S Cysteine-rich secretory protein family
NPKDGBBO_00928 9.8e-37 S Cysteine-rich secretory protein family
NPKDGBBO_00929 4.7e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NPKDGBBO_00930 5.4e-93
NPKDGBBO_00931 9.7e-203 yibE S overlaps another CDS with the same product name
NPKDGBBO_00932 1.3e-129 yibF S overlaps another CDS with the same product name
NPKDGBBO_00933 4.3e-160 I alpha/beta hydrolase fold
NPKDGBBO_00934 5.7e-29
NPKDGBBO_00935 0.0 G Belongs to the glycosyl hydrolase 31 family
NPKDGBBO_00936 5.7e-80 ntd 2.4.2.6 F Nucleoside
NPKDGBBO_00937 4.9e-90 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPKDGBBO_00938 1.7e-111 ptp3 3.1.3.48 T Tyrosine phosphatase family
NPKDGBBO_00939 1.7e-161 repA S Replication initiator protein A
NPKDGBBO_00940 7.6e-65 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NPKDGBBO_00941 5.6e-60 sthIM 2.1.1.72 L DNA methylase
NPKDGBBO_00942 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
NPKDGBBO_00943 3.9e-45 S MTH538 TIR-like domain (DUF1863)
NPKDGBBO_00944 8e-219 tnp L MULE transposase domain
NPKDGBBO_00946 1.4e-36 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NPKDGBBO_00947 8e-77 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NPKDGBBO_00948 3.7e-153 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NPKDGBBO_00949 3.3e-161 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NPKDGBBO_00950 5.4e-14 ydiN 5.4.99.5 G Major Facilitator
NPKDGBBO_00951 1.2e-118 ydiN G Major Facilitator Superfamily
NPKDGBBO_00952 5.6e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NPKDGBBO_00953 1.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPKDGBBO_00954 1.1e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPKDGBBO_00955 2.9e-276 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPKDGBBO_00956 7.9e-76 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPKDGBBO_00957 7.8e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPKDGBBO_00958 1.4e-93 sigH K Belongs to the sigma-70 factor family
NPKDGBBO_00959 2.2e-34
NPKDGBBO_00960 1.1e-283 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NPKDGBBO_00961 6.4e-88 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPKDGBBO_00962 7.5e-112 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPKDGBBO_00963 2.4e-98 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPKDGBBO_00964 5.9e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NPKDGBBO_00965 6.9e-101 nusG K Participates in transcription elongation, termination and antitermination
NPKDGBBO_00966 2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPKDGBBO_00967 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPKDGBBO_00968 3.5e-71 dedA 3.1.3.1 S SNARE associated Golgi protein
NPKDGBBO_00969 9.9e-250 yfnA E Amino Acid
NPKDGBBO_00970 3.3e-43 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPKDGBBO_00971 9.9e-78 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPKDGBBO_00972 1.1e-14 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPKDGBBO_00973 4.8e-45 yxeH S hydrolase
NPKDGBBO_00974 1.9e-84 yxeH S hydrolase
NPKDGBBO_00975 2.4e-158 S reductase
NPKDGBBO_00976 6e-219 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPKDGBBO_00977 2.2e-174 S cog cog1373
NPKDGBBO_00978 2.4e-218 pbuG S permease
NPKDGBBO_00979 1.6e-146 cof S haloacid dehalogenase-like hydrolase
NPKDGBBO_00980 1.4e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NPKDGBBO_00981 5.5e-118 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NPKDGBBO_00983 2.8e-20 ybbH_2 K rpiR family
NPKDGBBO_00984 2.1e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NPKDGBBO_00985 8e-42 S RelB antitoxin
NPKDGBBO_00986 2.8e-100 L Integrase
NPKDGBBO_00987 7.2e-47
NPKDGBBO_00988 2.8e-84 FG adenosine 5'-monophosphoramidase activity
NPKDGBBO_00989 3.9e-135 L Psort location Cytoplasmic, score
NPKDGBBO_00990 4.6e-42 L Psort location Cytoplasmic, score
NPKDGBBO_00991 3.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPKDGBBO_00992 9.2e-248 nhaC C Na H antiporter NhaC
NPKDGBBO_00993 3.5e-55
NPKDGBBO_00994 4.9e-120 ybhL S Belongs to the BI1 family
NPKDGBBO_00995 1.4e-114 S Protein of unknown function (DUF1211)
NPKDGBBO_00996 1e-170 yegS 2.7.1.107 G Lipid kinase
NPKDGBBO_00997 2.9e-276 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPKDGBBO_00998 9.9e-261 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPKDGBBO_00999 5.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPKDGBBO_01000 4.4e-211 camS S sex pheromone
NPKDGBBO_01001 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPKDGBBO_01002 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NPKDGBBO_01003 5e-103 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
NPKDGBBO_01005 2.1e-87 ydcK S Belongs to the SprT family
NPKDGBBO_01006 5.7e-137 M Glycosyltransferase sugar-binding region containing DXD motif
NPKDGBBO_01007 2.6e-261 epsU S Polysaccharide biosynthesis protein
NPKDGBBO_01008 1.9e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPKDGBBO_01009 2.2e-168 pacL 3.6.3.8 P P-type ATPase
NPKDGBBO_01010 1.6e-68 pacL 3.6.3.8 P P-type ATPase
NPKDGBBO_01011 4.5e-32 pacL 3.6.3.8 P P-type ATPase
NPKDGBBO_01012 5.6e-21 pacL 3.6.3.8 P P-type ATPase
NPKDGBBO_01013 1.6e-57 pacL 3.6.3.8 P P-type ATPase
NPKDGBBO_01014 1.2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NPKDGBBO_01015 9.7e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NPKDGBBO_01016 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NPKDGBBO_01017 4.9e-190 lacR K Transcriptional regulator
NPKDGBBO_01018 6e-24 lacS G Transporter
NPKDGBBO_01019 6.8e-48 lacS G Transporter
NPKDGBBO_01020 5.9e-70 lacS G Transporter
NPKDGBBO_01021 4e-57 lacS G Transporter
NPKDGBBO_01022 0.0 lacS G Transporter
NPKDGBBO_01023 2e-213 lacZ 3.2.1.23 G -beta-galactosidase
NPKDGBBO_01024 1.2e-91 L COG2963 Transposase and inactivated derivatives
NPKDGBBO_01025 1e-07 K LysR substrate binding domain
NPKDGBBO_01026 5.1e-63 K LysR substrate binding domain
NPKDGBBO_01027 0.0 clpE O Belongs to the ClpA ClpB family
NPKDGBBO_01028 3.9e-44 XK27_09445 S Domain of unknown function (DUF1827)
NPKDGBBO_01029 3.2e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NPKDGBBO_01030 1.2e-160 hlyX S Transporter associated domain
NPKDGBBO_01031 1.3e-73
NPKDGBBO_01032 1.9e-86
NPKDGBBO_01033 2.7e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
NPKDGBBO_01034 3.9e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPKDGBBO_01035 1.1e-112 L COG3385 FOG Transposase and inactivated derivatives
NPKDGBBO_01036 3.1e-83 L COG3385 FOG Transposase and inactivated derivatives
NPKDGBBO_01037 5e-41 L COG3385 FOG Transposase and inactivated derivatives
NPKDGBBO_01039 7.1e-103 yhdJ 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NPKDGBBO_01040 3.5e-101
NPKDGBBO_01041 7.5e-08
NPKDGBBO_01043 6.1e-08 ydcQ D FtsK/SpoIIIE family
NPKDGBBO_01044 2.3e-50 S Replication initiation factor
NPKDGBBO_01045 0.0 pepO 3.4.24.71 O Peptidase family M13
NPKDGBBO_01046 3.2e-228 yttB EGP Major facilitator Superfamily
NPKDGBBO_01047 6.1e-232 XK27_04775 S PAS domain
NPKDGBBO_01048 2.7e-100 S Iron-sulfur cluster assembly protein
NPKDGBBO_01049 4.3e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NPKDGBBO_01050 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NPKDGBBO_01053 9.5e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
NPKDGBBO_01054 0.0 asnB 6.3.5.4 E Asparagine synthase
NPKDGBBO_01055 1.3e-273 S Calcineurin-like phosphoesterase
NPKDGBBO_01056 8.7e-84
NPKDGBBO_01057 2e-108 tag 3.2.2.20 L glycosylase
NPKDGBBO_01058 1.2e-149 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NPKDGBBO_01059 9.1e-131 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NPKDGBBO_01060 5.2e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NPKDGBBO_01061 9.9e-153 phnD P Phosphonate ABC transporter
NPKDGBBO_01062 8.5e-87 uspA T universal stress protein
NPKDGBBO_01063 7.6e-203 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPKDGBBO_01064 0.0 dnaK O Heat shock 70 kDa protein
NPKDGBBO_01065 5.1e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPKDGBBO_01066 2.5e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPKDGBBO_01067 2.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NPKDGBBO_01068 2e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPKDGBBO_01069 4.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPKDGBBO_01070 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPKDGBBO_01071 1.2e-46 rplGA J ribosomal protein
NPKDGBBO_01072 8.8e-47 ylxR K Protein of unknown function (DUF448)
NPKDGBBO_01073 4.2e-201 nusA K Participates in both transcription termination and antitermination
NPKDGBBO_01074 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
NPKDGBBO_01075 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPKDGBBO_01076 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPKDGBBO_01077 2.3e-197 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NPKDGBBO_01078 1.6e-146 cdsA 2.7.7.41 I Belongs to the CDS family
NPKDGBBO_01079 1.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPKDGBBO_01080 4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPKDGBBO_01081 1.8e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NPKDGBBO_01082 2.2e-185 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPKDGBBO_01083 4.2e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
NPKDGBBO_01084 4.5e-199 yabB 2.1.1.223 L Methyltransferase small domain
NPKDGBBO_01085 4.1e-115 plsC 2.3.1.51 I Acyltransferase
NPKDGBBO_01086 1.4e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NPKDGBBO_01087 0.0 pepO 3.4.24.71 O Peptidase family M13
NPKDGBBO_01088 1.6e-271 mdlB V ABC transporter
NPKDGBBO_01089 3.1e-152 mdlA V ABC transporter
NPKDGBBO_01090 7.9e-114 L Transposase
NPKDGBBO_01091 1.4e-57 S Alpha beta hydrolase
NPKDGBBO_01092 2.1e-39 S Hydrolases of the alpha beta superfamily
NPKDGBBO_01093 9.9e-143 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NPKDGBBO_01094 3.2e-47 1.1.1.3 T phosphoserine phosphatase activity
NPKDGBBO_01095 6.6e-84 K Bacterial regulatory proteins, tetR family
NPKDGBBO_01096 4.3e-109 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NPKDGBBO_01097 5.2e-98 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NPKDGBBO_01098 8.4e-153 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
NPKDGBBO_01099 2e-94 K acetyltransferase
NPKDGBBO_01100 1.2e-85 dps P Belongs to the Dps family
NPKDGBBO_01101 2.3e-166 snf 2.7.11.1 KL domain protein
NPKDGBBO_01102 1.3e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPKDGBBO_01103 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPKDGBBO_01104 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPKDGBBO_01105 1.6e-169 K Transcriptional regulator
NPKDGBBO_01106 1.1e-164 ppaC 3.6.1.1 C inorganic pyrophosphatase
NPKDGBBO_01107 1.9e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPKDGBBO_01108 2.1e-55 K Helix-turn-helix domain
NPKDGBBO_01109 3.1e-49 2.7.7.12 C Domain of unknown function (DUF4931)
NPKDGBBO_01110 1.2e-120
NPKDGBBO_01111 2.6e-143 S Belongs to the UPF0246 family
NPKDGBBO_01112 2.9e-142 aroD S Alpha/beta hydrolase family
NPKDGBBO_01113 1.2e-111 G phosphoglycerate mutase
NPKDGBBO_01114 5.3e-95 ygfC K Bacterial regulatory proteins, tetR family
NPKDGBBO_01115 1.5e-168 hrtB V ABC transporter permease
NPKDGBBO_01116 8.8e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NPKDGBBO_01117 4.3e-277 pipD E Dipeptidase
NPKDGBBO_01118 1.1e-10
NPKDGBBO_01119 5.5e-89
NPKDGBBO_01120 9.9e-132 K Helix-turn-helix XRE-family like proteins
NPKDGBBO_01121 1.5e-279 S SLAP domain
NPKDGBBO_01122 2.2e-71 S Protein of unknown function (DUF3232)
NPKDGBBO_01124 1.9e-83
NPKDGBBO_01125 2.2e-46 K Helix-turn-helix XRE-family like proteins
NPKDGBBO_01126 1.4e-75 K Helix-turn-helix XRE-family like proteins
NPKDGBBO_01127 9.8e-118 KLT serine threonine protein kinase
NPKDGBBO_01128 3.3e-289 V ABC transporter transmembrane region
NPKDGBBO_01129 1.1e-27
NPKDGBBO_01130 3e-122 gntR1 K UTRA
NPKDGBBO_01131 4.1e-214
NPKDGBBO_01134 1.1e-133 slpX S SLAP domain
NPKDGBBO_01135 9.5e-11 pfoS S Phosphotransferase system, EIIC
NPKDGBBO_01136 5.9e-77 pfoS S Phosphotransferase system, EIIC
NPKDGBBO_01137 1.5e-19 pfoS S Phosphotransferase system, EIIC
NPKDGBBO_01139 1.4e-87 S SLAP domain
NPKDGBBO_01140 3.5e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPKDGBBO_01141 4.2e-55 2.7.1.2 GK ROK family
NPKDGBBO_01142 2.8e-68 GK ROK family
NPKDGBBO_01143 5.5e-43
NPKDGBBO_01144 1.2e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPKDGBBO_01145 5.5e-68 S Domain of unknown function (DUF1934)
NPKDGBBO_01146 3.3e-55 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPKDGBBO_01147 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPKDGBBO_01148 3.6e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPKDGBBO_01149 3.2e-33 S Haloacid dehalogenase-like hydrolase
NPKDGBBO_01150 1.8e-47 S Haloacid dehalogenase-like hydrolase
NPKDGBBO_01151 4.1e-283 pipD E Dipeptidase
NPKDGBBO_01152 1.1e-158 msmR K AraC-like ligand binding domain
NPKDGBBO_01153 8.6e-224 pbuX F xanthine permease
NPKDGBBO_01154 7.4e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPKDGBBO_01155 1.6e-106 K DNA-binding helix-turn-helix protein
NPKDGBBO_01156 1e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
NPKDGBBO_01157 0.0 S membrane
NPKDGBBO_01158 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NPKDGBBO_01159 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NPKDGBBO_01160 1.7e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPKDGBBO_01161 3.7e-117 gluP 3.4.21.105 S Rhomboid family
NPKDGBBO_01162 5.6e-33 yqgQ S Bacterial protein of unknown function (DUF910)
NPKDGBBO_01163 1.7e-69 yqhL P Rhodanese-like protein
NPKDGBBO_01164 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPKDGBBO_01165 1.1e-71 L IS1381, transposase OrfA
NPKDGBBO_01166 5.5e-21 ynbB 4.4.1.1 P aluminum resistance
NPKDGBBO_01167 2.4e-64 ynbB 4.4.1.1 P aluminum resistance
NPKDGBBO_01168 4e-264 glnA 6.3.1.2 E glutamine synthetase
NPKDGBBO_01169 5.5e-135
NPKDGBBO_01170 1.1e-164
NPKDGBBO_01171 2.9e-150
NPKDGBBO_01172 1.7e-14
NPKDGBBO_01173 9.9e-163 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPKDGBBO_01174 6.8e-83 S Peptidase family M23
NPKDGBBO_01175 5.8e-152 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NPKDGBBO_01176 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NPKDGBBO_01177 3.2e-69 yqeY S YqeY-like protein
NPKDGBBO_01178 4.2e-175 phoH T phosphate starvation-inducible protein PhoH
NPKDGBBO_01179 1.6e-96 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPKDGBBO_01180 1.1e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPKDGBBO_01181 3e-136 recO L Involved in DNA repair and RecF pathway recombination
NPKDGBBO_01182 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NPKDGBBO_01183 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NPKDGBBO_01184 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPKDGBBO_01185 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPKDGBBO_01186 1.2e-125 S Peptidase family M23
NPKDGBBO_01187 1.1e-29 mutT 3.6.1.55 F NUDIX domain
NPKDGBBO_01188 2.9e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
NPKDGBBO_01189 7.7e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPKDGBBO_01190 8e-243 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NPKDGBBO_01191 6.8e-57 asp S Asp23 family, cell envelope-related function
NPKDGBBO_01192 4e-306 yloV S DAK2 domain fusion protein YloV
NPKDGBBO_01193 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPKDGBBO_01194 9.9e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPKDGBBO_01195 3.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPKDGBBO_01196 7.3e-197 oppD P Belongs to the ABC transporter superfamily
NPKDGBBO_01197 2.8e-182 oppF P Belongs to the ABC transporter superfamily
NPKDGBBO_01198 1.7e-176 oppB P ABC transporter permease
NPKDGBBO_01199 6.6e-149 oppC P Binding-protein-dependent transport system inner membrane component
NPKDGBBO_01200 0.0 oppA E ABC transporter substrate-binding protein
NPKDGBBO_01201 9.4e-302 oppA E ABC transporter substrate-binding protein
NPKDGBBO_01202 1.3e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPKDGBBO_01203 0.0 smc D Required for chromosome condensation and partitioning
NPKDGBBO_01204 1.3e-166 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPKDGBBO_01205 7.6e-252 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPKDGBBO_01206 2.9e-99 J Acetyltransferase (GNAT) domain
NPKDGBBO_01207 6.8e-110 yjbF S SNARE associated Golgi protein
NPKDGBBO_01208 3.4e-154 I alpha/beta hydrolase fold
NPKDGBBO_01210 5.9e-126 hipB K Helix-turn-helix
NPKDGBBO_01211 3.9e-262 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NPKDGBBO_01212 6.6e-158
NPKDGBBO_01213 0.0 ydgH S MMPL family
NPKDGBBO_01214 1.5e-98 yobS K Bacterial regulatory proteins, tetR family
NPKDGBBO_01215 5.5e-159 3.5.2.6 V Beta-lactamase enzyme family
NPKDGBBO_01216 7.4e-161 corA P CorA-like Mg2+ transporter protein
NPKDGBBO_01217 6.3e-238 G Bacterial extracellular solute-binding protein
NPKDGBBO_01218 2.3e-256 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
NPKDGBBO_01219 1.6e-146 gtsC P Binding-protein-dependent transport system inner membrane component
NPKDGBBO_01220 1.9e-158 gtsB P ABC-type sugar transport systems, permease components
NPKDGBBO_01221 1.4e-203 malK P ATPases associated with a variety of cellular activities
NPKDGBBO_01222 1.1e-280 pipD E Dipeptidase
NPKDGBBO_01223 2.5e-158 endA F DNA RNA non-specific endonuclease
NPKDGBBO_01224 5.7e-164 dnaQ 2.7.7.7 L EXOIII
NPKDGBBO_01225 3.7e-159 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NPKDGBBO_01226 4.3e-40 L An automated process has identified a potential problem with this gene model
NPKDGBBO_01227 1.4e-24 L An automated process has identified a potential problem with this gene model
NPKDGBBO_01229 6.5e-47
NPKDGBBO_01230 1.6e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NPKDGBBO_01231 6.1e-219 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NPKDGBBO_01232 1.2e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
NPKDGBBO_01233 2.4e-126 L transposase, IS605 OrfB family
NPKDGBBO_01234 9.6e-27 L transposase, IS605 OrfB family
NPKDGBBO_01235 3.1e-167 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NPKDGBBO_01236 1.4e-151 yihY S Belongs to the UPF0761 family
NPKDGBBO_01237 8.5e-164 map 3.4.11.18 E Methionine Aminopeptidase
NPKDGBBO_01238 1.6e-79 fld C Flavodoxin
NPKDGBBO_01239 3.1e-90 gtcA S Teichoic acid glycosylation protein
NPKDGBBO_01240 3.8e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPKDGBBO_01241 1.2e-25
NPKDGBBO_01243 6.4e-246 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPKDGBBO_01244 1.1e-207 yfmL 3.6.4.13 L DEAD DEAH box helicase
NPKDGBBO_01245 2.6e-35 M Glycosyl hydrolases family 25
NPKDGBBO_01246 1.6e-188 cggR K Putative sugar-binding domain
NPKDGBBO_01247 1.3e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPKDGBBO_01248 9.3e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NPKDGBBO_01249 2e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPKDGBBO_01250 4.8e-96
NPKDGBBO_01251 8.7e-159 ycsE S Sucrose-6F-phosphate phosphohydrolase
NPKDGBBO_01252 3.3e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPKDGBBO_01253 1.8e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NPKDGBBO_01254 6.4e-90 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NPKDGBBO_01255 2.3e-98 dnaQ 2.7.7.7 L DNA polymerase III
NPKDGBBO_01256 1.1e-164 murB 1.3.1.98 M Cell wall formation
NPKDGBBO_01257 3.9e-187 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NPKDGBBO_01258 1.3e-129 potB P ABC transporter permease
NPKDGBBO_01259 1.7e-132 potC P ABC transporter permease
NPKDGBBO_01260 5.6e-208 potD P ABC transporter
NPKDGBBO_01261 4.2e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPKDGBBO_01262 2.4e-170 ybbR S YbbR-like protein
NPKDGBBO_01263 1.3e-257 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPKDGBBO_01264 1.1e-150 S hydrolase
NPKDGBBO_01265 1.5e-149 S Sucrose-6F-phosphate phosphohydrolase
NPKDGBBO_01266 2.1e-118
NPKDGBBO_01267 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPKDGBBO_01268 3.5e-216 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NPKDGBBO_01269 4.6e-64 licT K CAT RNA binding domain
NPKDGBBO_01270 3e-63 licT K CAT RNA binding domain
NPKDGBBO_01271 0.0 bglP G phosphotransferase system
NPKDGBBO_01272 9.5e-166 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPKDGBBO_01273 1.1e-38 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPKDGBBO_01274 4.3e-61 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPKDGBBO_01275 5.9e-185 D Alpha beta
NPKDGBBO_01276 1.5e-16 E Amino acid permease
NPKDGBBO_01277 2.5e-162 E Amino acid permease
NPKDGBBO_01278 1.7e-56 E Amino acid permease
NPKDGBBO_01279 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NPKDGBBO_01280 6.4e-120 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
NPKDGBBO_01281 5.2e-164 L Belongs to the 'phage' integrase family
NPKDGBBO_01282 6.5e-54 M Glycosyl hydrolases family 25
NPKDGBBO_01283 4.3e-37 potE E amino acid
NPKDGBBO_01284 5.4e-156 potE E amino acid
NPKDGBBO_01285 2.2e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NPKDGBBO_01286 1.1e-240 yhdP S Transporter associated domain
NPKDGBBO_01287 1.4e-47 C nitroreductase
NPKDGBBO_01288 2.5e-18 C nitroreductase
NPKDGBBO_01289 6.2e-39
NPKDGBBO_01290 1.6e-239 pyrP F Permease
NPKDGBBO_01291 1.5e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPKDGBBO_01292 7.8e-261 emrY EGP Major facilitator Superfamily
NPKDGBBO_01293 9.6e-217 mdtG EGP Major facilitator Superfamily
NPKDGBBO_01294 1.1e-208 pepA E M42 glutamyl aminopeptidase
NPKDGBBO_01295 3e-119 ybiT S ABC transporter, ATP-binding protein
NPKDGBBO_01296 1.5e-126 ybiT S ABC transporter, ATP-binding protein
NPKDGBBO_01297 6.2e-11
NPKDGBBO_01298 2e-123
NPKDGBBO_01299 4.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
NPKDGBBO_01300 9.9e-149 glnH ET ABC transporter
NPKDGBBO_01301 8.8e-81 K Transcriptional regulator, MarR family
NPKDGBBO_01302 9.8e-287 XK27_09600 V ABC transporter, ATP-binding protein
NPKDGBBO_01303 0.0 V ABC transporter transmembrane region
NPKDGBBO_01304 2.9e-102 S ABC-type cobalt transport system, permease component
NPKDGBBO_01305 8.1e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPKDGBBO_01306 1.6e-70 yqhY S Asp23 family, cell envelope-related function
NPKDGBBO_01307 2.2e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPKDGBBO_01308 2e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NPKDGBBO_01309 2.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NPKDGBBO_01310 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NPKDGBBO_01311 1.3e-257 S Uncharacterized protein conserved in bacteria (DUF2325)
NPKDGBBO_01312 5.3e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NPKDGBBO_01313 2.5e-129 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NPKDGBBO_01314 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NPKDGBBO_01315 0.0 S Predicted membrane protein (DUF2207)
NPKDGBBO_01316 3.3e-209 M Glycosyl hydrolases family 25
NPKDGBBO_01318 4.5e-179 I Carboxylesterase family
NPKDGBBO_01319 3e-65 arsC 1.20.4.1 P Belongs to the ArsC family
NPKDGBBO_01320 1.7e-21
NPKDGBBO_01321 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NPKDGBBO_01322 2.5e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NPKDGBBO_01323 2e-48
NPKDGBBO_01324 6.8e-152 glcU U sugar transport
NPKDGBBO_01326 1.7e-43
NPKDGBBO_01327 6.3e-91 bioY S BioY family
NPKDGBBO_01328 4.1e-189 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPKDGBBO_01329 9.9e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NPKDGBBO_01330 4.1e-144 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NPKDGBBO_01331 2.7e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NPKDGBBO_01332 2.5e-261 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NPKDGBBO_01333 2.7e-73 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NPKDGBBO_01334 6.2e-79 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NPKDGBBO_01335 1.6e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPKDGBBO_01336 1.7e-128 IQ reductase
NPKDGBBO_01337 1.5e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NPKDGBBO_01338 1.4e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPKDGBBO_01339 1.3e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPKDGBBO_01340 9.6e-80 marR K Transcriptional regulator
NPKDGBBO_01341 3.8e-78 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NPKDGBBO_01342 1e-188 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
NPKDGBBO_01343 1.8e-13 ytgB S Transglycosylase associated protein
NPKDGBBO_01344 1.3e-102 L Resolvase, N terminal domain
NPKDGBBO_01345 1e-129 L Transposase
NPKDGBBO_01346 5.1e-63 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPKDGBBO_01347 5.7e-158 glcU U sugar transport
NPKDGBBO_01348 1.3e-78 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPKDGBBO_01349 4.1e-71 S CAAX protease self-immunity
NPKDGBBO_01352 2.2e-160 S SLAP domain
NPKDGBBO_01353 3e-80 S Bacteriocin helveticin-J
NPKDGBBO_01354 1.4e-42
NPKDGBBO_01355 1.4e-38 ps115 K Helix-turn-helix XRE-family like proteins
NPKDGBBO_01356 6.9e-48 E Zn peptidase
NPKDGBBO_01357 4.7e-198 EGP Major facilitator Superfamily
NPKDGBBO_01358 1e-119 ropB K Transcriptional regulator
NPKDGBBO_01359 0.0 traA L MobA MobL family protein
NPKDGBBO_01360 3.5e-264 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NPKDGBBO_01361 3.8e-31
NPKDGBBO_01362 5.8e-200 L Psort location Cytoplasmic, score
NPKDGBBO_01363 3.8e-248 L Transposase
NPKDGBBO_01364 8.3e-228 nhaC C Na H antiporter NhaC
NPKDGBBO_01365 1.6e-87 pfoS S Phosphotransferase system, EIIC
NPKDGBBO_01366 2.6e-175 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPKDGBBO_01367 2.7e-216 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NPKDGBBO_01368 8.9e-10
NPKDGBBO_01369 1.9e-75 WQ51_05710 S Mitochondrial biogenesis AIM24
NPKDGBBO_01370 5.3e-192 L Transposase and inactivated derivatives, IS30 family
NPKDGBBO_01371 2.5e-116 S Abortive infection C-terminus
NPKDGBBO_01373 6.1e-134 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NPKDGBBO_01374 2.3e-99 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NPKDGBBO_01375 2.8e-08 cylB V ABC-2 type transporter
NPKDGBBO_01376 4.2e-217 L Transposase
NPKDGBBO_01377 3.7e-116 P ABC transporter
NPKDGBBO_01378 3.6e-51 L COG2826 Transposase and inactivated derivatives, IS30 family
NPKDGBBO_01379 1.6e-91
NPKDGBBO_01380 6.4e-26
NPKDGBBO_01381 1.4e-49
NPKDGBBO_01382 1.2e-103 2.7.1.199, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NPKDGBBO_01383 1.4e-15 scrR K Transcriptional regulator, LacI family
NPKDGBBO_01384 1.1e-93 scrR K Transcriptional regulator, LacI family
NPKDGBBO_01385 6.5e-123 liaI S membrane
NPKDGBBO_01386 7.9e-79 XK27_02470 K LytTr DNA-binding domain
NPKDGBBO_01387 1.7e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPKDGBBO_01388 0.0 uup S ABC transporter, ATP-binding protein
NPKDGBBO_01389 1.1e-12 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NPKDGBBO_01390 5.7e-215 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NPKDGBBO_01391 1.1e-37 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NPKDGBBO_01392 1.1e-26 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NPKDGBBO_01393 1.1e-74 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NPKDGBBO_01394 1.9e-80 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NPKDGBBO_01395 6.5e-234 yfdE 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NPKDGBBO_01396 1.7e-19 S Toxin ToxN, type III toxin-antitoxin system
NPKDGBBO_01397 8.4e-63 S Uncharacterised protein family (UPF0236)
NPKDGBBO_01398 8e-78 S Uncharacterised protein family (UPF0236)
NPKDGBBO_01399 1.2e-231 pbuG S permease
NPKDGBBO_01400 4.2e-133 K helix_turn_helix, mercury resistance
NPKDGBBO_01401 3.2e-10 S cog cog1373
NPKDGBBO_01402 4.3e-12 M NlpC/P60 family
NPKDGBBO_01403 1.1e-22 M NlpC/P60 family
NPKDGBBO_01404 4.7e-93 M NlpC/P60 family
NPKDGBBO_01405 1.2e-131 G Peptidase_C39 like family
NPKDGBBO_01406 8.9e-26
NPKDGBBO_01408 1.1e-30
NPKDGBBO_01410 1.2e-267 S SLAP domain
NPKDGBBO_01411 2.5e-07
NPKDGBBO_01413 1.3e-93 O Belongs to the peptidase S8 family
NPKDGBBO_01414 6.5e-65 O Belongs to the peptidase S8 family
NPKDGBBO_01415 2.5e-35 infB UW LPXTG-motif cell wall anchor domain protein
NPKDGBBO_01416 6.8e-18 infB UW LPXTG-motif cell wall anchor domain protein
NPKDGBBO_01417 9.6e-35 infB UW LPXTG-motif cell wall anchor domain protein
NPKDGBBO_01418 2.7e-19 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
NPKDGBBO_01419 9.8e-58 CO Thioredoxin
NPKDGBBO_01420 9.4e-118 M1-798 K Rhodanese Homology Domain
NPKDGBBO_01421 4.1e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPKDGBBO_01422 1.7e-10 frnE Q DSBA-like thioredoxin domain
NPKDGBBO_01423 1.2e-18 frnE Q DSBA-like thioredoxin domain
NPKDGBBO_01424 2.4e-29 Q DSBA-like thioredoxin domain
NPKDGBBO_01425 1.6e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPKDGBBO_01426 2.5e-30 yneF S Uncharacterised protein family (UPF0154)
NPKDGBBO_01427 5.1e-38 ynzC S UPF0291 protein
NPKDGBBO_01428 3.6e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NPKDGBBO_01429 8.3e-148 E GDSL-like Lipase/Acylhydrolase family
NPKDGBBO_01430 6e-45 ung2 3.2.2.27 L Uracil-DNA glycosylase
NPKDGBBO_01431 1.5e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPKDGBBO_01432 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NPKDGBBO_01433 1.5e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPKDGBBO_01434 4.5e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NPKDGBBO_01435 2.2e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPKDGBBO_01436 3.2e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPKDGBBO_01437 1.4e-133 L Transposase and inactivated derivatives, IS30 family
NPKDGBBO_01438 4.9e-260 yfnA E amino acid
NPKDGBBO_01439 5.2e-44
NPKDGBBO_01440 1.7e-289 pipD E Dipeptidase
NPKDGBBO_01442 1.2e-155 P ABC-type cobalt transport system permease component CbiQ and related transporters
NPKDGBBO_01443 0.0 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
NPKDGBBO_01444 3.3e-124 S ECF-type riboflavin transporter, S component
NPKDGBBO_01445 8.8e-85 U FFAT motif binding
NPKDGBBO_01446 7.3e-44 U FFAT motif binding
NPKDGBBO_01447 1.9e-53 eutP E Ethanolamine utilisation - propanediol utilisation
NPKDGBBO_01448 3.9e-60 yvoA_1 K Transcriptional regulator, GntR family
NPKDGBBO_01449 2.4e-122 skfE V ATPases associated with a variety of cellular activities
NPKDGBBO_01450 6.7e-148
NPKDGBBO_01451 1.9e-147
NPKDGBBO_01452 1.1e-130
NPKDGBBO_01453 3.9e-33 rarA L recombination factor protein RarA
NPKDGBBO_01454 7.8e-61 rarA L recombination factor protein RarA
NPKDGBBO_01455 7.8e-28
NPKDGBBO_01456 2.4e-36 L An automated process has identified a potential problem with this gene model
NPKDGBBO_01457 7.3e-177 lacX 5.1.3.3 G Aldose 1-epimerase
NPKDGBBO_01458 2.9e-233 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NPKDGBBO_01459 1.1e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NPKDGBBO_01460 1.3e-168 xerC D Phage integrase, N-terminal SAM-like domain
NPKDGBBO_01461 1.9e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NPKDGBBO_01462 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPKDGBBO_01463 1.1e-155 dprA LU DNA protecting protein DprA
NPKDGBBO_01464 2.9e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPKDGBBO_01465 7.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPKDGBBO_01466 4e-279 yjcE P Sodium proton antiporter
NPKDGBBO_01467 9.3e-36 yozE S Belongs to the UPF0346 family
NPKDGBBO_01468 7.7e-149 DegV S Uncharacterised protein, DegV family COG1307
NPKDGBBO_01469 6.7e-114 hlyIII S protein, hemolysin III
NPKDGBBO_01470 3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPKDGBBO_01471 4.2e-161 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPKDGBBO_01472 2.3e-229 S Tetratricopeptide repeat protein
NPKDGBBO_01473 3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPKDGBBO_01474 2.8e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NPKDGBBO_01475 3.3e-209 rpsA 1.17.7.4 J Ribosomal protein S1
NPKDGBBO_01476 3.5e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NPKDGBBO_01477 2.4e-30 M Lysin motif
NPKDGBBO_01478 5.7e-113 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPKDGBBO_01479 1e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPKDGBBO_01480 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPKDGBBO_01481 2.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPKDGBBO_01482 4.9e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPKDGBBO_01483 4e-167 xerD D recombinase XerD
NPKDGBBO_01484 5e-170 cvfB S S1 domain
NPKDGBBO_01485 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NPKDGBBO_01486 1.2e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NPKDGBBO_01487 0.0 dnaE 2.7.7.7 L DNA polymerase
NPKDGBBO_01488 2.5e-22 S Protein of unknown function (DUF2929)
NPKDGBBO_01489 1.3e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NPKDGBBO_01490 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NPKDGBBO_01491 6.2e-33 yrvD S Lipopolysaccharide assembly protein A domain
NPKDGBBO_01492 1.4e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NPKDGBBO_01493 3.1e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPKDGBBO_01494 0.0 oatA I Acyltransferase
NPKDGBBO_01495 1.4e-242 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPKDGBBO_01496 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPKDGBBO_01497 1.3e-154 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPKDGBBO_01498 8e-28
NPKDGBBO_01499 7.6e-79 hit FG Scavenger mRNA decapping enzyme C-term binding
NPKDGBBO_01500 3.8e-54 higA K Helix-turn-helix XRE-family like proteins
NPKDGBBO_01501 1.1e-135 ecsA V ABC transporter, ATP-binding protein
NPKDGBBO_01502 1.7e-213 ecsB U ABC transporter
NPKDGBBO_01503 1e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPKDGBBO_01504 7.3e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NPKDGBBO_01505 3.3e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPKDGBBO_01506 0.0 S SLAP domain
NPKDGBBO_01507 5.5e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NPKDGBBO_01508 8.2e-174 S SLAP domain
NPKDGBBO_01509 2.2e-287 M Peptidase family M1 domain
NPKDGBBO_01510 2.9e-195 S Bacteriocin helveticin-J
NPKDGBBO_01511 7.6e-65 L Transposase IS200 like
NPKDGBBO_01512 1.6e-174 L transposase, IS605 OrfB family
NPKDGBBO_01513 1.7e-51 L RelB antitoxin
NPKDGBBO_01514 2.6e-139 qmcA O prohibitin homologues
NPKDGBBO_01515 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NPKDGBBO_01516 3.1e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NPKDGBBO_01517 8.2e-221 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NPKDGBBO_01518 2.1e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NPKDGBBO_01519 6.4e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPKDGBBO_01520 1.8e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPKDGBBO_01521 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPKDGBBO_01522 1.5e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NPKDGBBO_01523 2.5e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NPKDGBBO_01524 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NPKDGBBO_01525 1.4e-289 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NPKDGBBO_01526 9.7e-236 purD 6.3.4.13 F Belongs to the GARS family
NPKDGBBO_01528 1.5e-39
NPKDGBBO_01529 3.4e-146 sufC O FeS assembly ATPase SufC
NPKDGBBO_01530 1.8e-229 sufD O FeS assembly protein SufD
NPKDGBBO_01531 2.8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NPKDGBBO_01532 3.8e-81 nifU C SUF system FeS assembly protein, NifU family
NPKDGBBO_01533 3.2e-272 sufB O assembly protein SufB
NPKDGBBO_01534 2.5e-55 yitW S Iron-sulfur cluster assembly protein
NPKDGBBO_01535 3.2e-62 S Enterocin A Immunity
NPKDGBBO_01536 1.4e-128 glcR K DeoR C terminal sensor domain
NPKDGBBO_01537 6e-76 L COG2826 Transposase and inactivated derivatives, IS30 family
NPKDGBBO_01538 5.4e-69 K DNA-binding transcription factor activity
NPKDGBBO_01539 0.0 O Belongs to the peptidase S8 family
NPKDGBBO_01540 1.2e-123 O Belongs to the peptidase S8 family
NPKDGBBO_01541 3e-110 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NPKDGBBO_01542 5.3e-101 G Aldose 1-epimerase
NPKDGBBO_01543 7.5e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NPKDGBBO_01544 5.6e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPKDGBBO_01545 0.0 XK27_08315 M Sulfatase
NPKDGBBO_01546 9e-267 S Fibronectin type III domain
NPKDGBBO_01547 3.7e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPKDGBBO_01548 1.2e-53
NPKDGBBO_01550 1.6e-257 pepC 3.4.22.40 E aminopeptidase
NPKDGBBO_01551 9.8e-123 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPKDGBBO_01552 1.9e-300 oppA E ABC transporter, substratebinding protein
NPKDGBBO_01553 2.2e-106 oppA E ABC transporter, substratebinding protein
NPKDGBBO_01554 2.8e-105 lepB 3.4.21.89 U Peptidase S24-like
NPKDGBBO_01555 7.8e-140
NPKDGBBO_01556 6.9e-181
NPKDGBBO_01557 1.7e-262 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
NPKDGBBO_01558 6.7e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPKDGBBO_01559 4.2e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NPKDGBBO_01560 7.5e-180 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NPKDGBBO_01561 1.1e-167 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
NPKDGBBO_01562 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NPKDGBBO_01563 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NPKDGBBO_01564 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NPKDGBBO_01565 2.9e-90 ypmB S Protein conserved in bacteria
NPKDGBBO_01566 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NPKDGBBO_01567 7.4e-115 dnaD L DnaD domain protein
NPKDGBBO_01568 3.9e-113 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NPKDGBBO_01569 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NPKDGBBO_01570 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPKDGBBO_01571 1.7e-107 ypsA S Belongs to the UPF0398 family
NPKDGBBO_01572 1.4e-69 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPKDGBBO_01573 1e-220 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NPKDGBBO_01574 6.5e-11 cpdA S Calcineurin-like phosphoesterase
NPKDGBBO_01575 2.6e-87 cpdA S Calcineurin-like phosphoesterase
NPKDGBBO_01576 1.6e-80 cpdA S Calcineurin-like phosphoesterase
NPKDGBBO_01577 3.2e-289 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NPKDGBBO_01578 4.1e-17 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NPKDGBBO_01579 7.3e-80 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPKDGBBO_01580 1.6e-168 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPKDGBBO_01581 3e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NPKDGBBO_01582 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
NPKDGBBO_01583 0.0 FbpA K Fibronectin-binding protein
NPKDGBBO_01584 7.7e-65
NPKDGBBO_01585 3.5e-160 degV S EDD domain protein, DegV family
NPKDGBBO_01586 7.6e-205 xerS L Belongs to the 'phage' integrase family
NPKDGBBO_01587 1.8e-67
NPKDGBBO_01588 1.3e-78 adk 2.7.4.3 F topology modulation protein
NPKDGBBO_01589 1.2e-109 XK27_00160 S Domain of unknown function (DUF5052)
NPKDGBBO_01590 1.4e-54
NPKDGBBO_01591 8.2e-28 M Glycosyl hydrolases family 25
NPKDGBBO_01592 1.7e-33 M Glycosyl hydrolases family 25
NPKDGBBO_01593 1.1e-47 M Glycosyl hydrolases family 25
NPKDGBBO_01594 2.3e-25 lysA2 M Glycosyl hydrolases family 25
NPKDGBBO_01595 3.5e-62 L the current gene model (or a revised gene model) may contain a
NPKDGBBO_01599 7.9e-188 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
NPKDGBBO_01601 5.1e-274 V ABC-type multidrug transport system, ATPase and permease components
NPKDGBBO_01602 5.7e-286 V ABC-type multidrug transport system, ATPase and permease components
NPKDGBBO_01603 1.4e-47 L Transposase
NPKDGBBO_01604 3.7e-240 I Protein of unknown function (DUF2974)
NPKDGBBO_01605 1.4e-122 yhiD S MgtC family
NPKDGBBO_01607 4.4e-209 2.1.1.72 L PFAM DNA methylase N-4 N-6 domain protein
NPKDGBBO_01608 2.2e-301 3.1.21.5 L Type III restriction enzyme, res subunit
NPKDGBBO_01609 4.8e-82 racA K Domain of unknown function (DUF1836)
NPKDGBBO_01610 2.6e-152 yitS S EDD domain protein, DegV family
NPKDGBBO_01612 2.1e-19 UW LPXTG-motif cell wall anchor domain protein
NPKDGBBO_01613 3.1e-150 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NPKDGBBO_01614 9.8e-55
NPKDGBBO_01615 1.1e-138 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NPKDGBBO_01616 6.9e-136 mgtC S MgtC family
NPKDGBBO_01617 1.9e-09 5.3.3.2 C FMN-dependent dehydrogenase
NPKDGBBO_01618 1.4e-21 bglH 3.2.1.86 GT1 G beta-glucosidase activity
NPKDGBBO_01619 4.9e-184 S AAA domain
NPKDGBBO_01620 2.6e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPKDGBBO_01621 2.5e-23
NPKDGBBO_01622 1.1e-161 czcD P cation diffusion facilitator family transporter
NPKDGBBO_01623 2e-126 pgm3 G Belongs to the phosphoglycerate mutase family
NPKDGBBO_01624 6.4e-134 S membrane transporter protein
NPKDGBBO_01625 9.8e-14 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NPKDGBBO_01626 1.7e-64 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NPKDGBBO_01627 1.1e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NPKDGBBO_01628 3.2e-62 S Protein of unknown function (DUF805)
NPKDGBBO_01629 1.4e-48 K Putative DNA-binding domain
NPKDGBBO_01630 0.0 V Type II restriction enzyme, methylase subunits
NPKDGBBO_01632 4e-18
NPKDGBBO_01633 2.5e-70 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NPKDGBBO_01634 3.5e-11
NPKDGBBO_01635 1.3e-159 repB EP Plasmid replication protein
NPKDGBBO_01636 1.6e-25
NPKDGBBO_01637 1.9e-197 L Phage integrase family
NPKDGBBO_01638 1.6e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
NPKDGBBO_01639 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPKDGBBO_01640 4.6e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPKDGBBO_01641 6.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPKDGBBO_01642 1.5e-152 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPKDGBBO_01643 2.2e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPKDGBBO_01644 1.1e-60 rplQ J Ribosomal protein L17
NPKDGBBO_01645 8.1e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPKDGBBO_01646 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPKDGBBO_01647 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPKDGBBO_01648 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NPKDGBBO_01649 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPKDGBBO_01650 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPKDGBBO_01651 4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPKDGBBO_01652 1.5e-71 rplO J Binds to the 23S rRNA
NPKDGBBO_01653 2.3e-24 rpmD J Ribosomal protein L30
NPKDGBBO_01654 1.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPKDGBBO_01655 2.2e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPKDGBBO_01656 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPKDGBBO_01657 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPKDGBBO_01658 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPKDGBBO_01659 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPKDGBBO_01660 4.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPKDGBBO_01661 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPKDGBBO_01662 1.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPKDGBBO_01663 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NPKDGBBO_01664 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPKDGBBO_01665 2e-110 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPKDGBBO_01666 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPKDGBBO_01667 4.2e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPKDGBBO_01668 1.2e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPKDGBBO_01669 4.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPKDGBBO_01670 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
NPKDGBBO_01671 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPKDGBBO_01672 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NPKDGBBO_01673 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPKDGBBO_01674 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPKDGBBO_01675 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPKDGBBO_01676 3.9e-122 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NPKDGBBO_01677 1.1e-211 S Uncharacterised protein family (UPF0236)
NPKDGBBO_01678 4.9e-58 yufP S Belongs to the binding-protein-dependent transport system permease family
NPKDGBBO_01679 1.4e-26 yufQ S Belongs to the binding-protein-dependent transport system permease family
NPKDGBBO_01680 1.2e-112 yufQ S Belongs to the binding-protein-dependent transport system permease family
NPKDGBBO_01681 0.0 3.6.3.8 P P-type ATPase
NPKDGBBO_01682 3.5e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NPKDGBBO_01683 1.7e-90 3.6.1.55 L NUDIX domain
NPKDGBBO_01684 1.1e-38
NPKDGBBO_01685 1.7e-31
NPKDGBBO_01686 6.6e-290 V ABC-type multidrug transport system, ATPase and permease components
NPKDGBBO_01687 3.4e-286 V ABC-type multidrug transport system, ATPase and permease components
NPKDGBBO_01689 4.4e-16 L PFAM IS66 Orf2 family protein
NPKDGBBO_01690 1.2e-08
NPKDGBBO_01691 3.3e-14 S Phage derived protein Gp49-like (DUF891)
NPKDGBBO_01692 2.9e-168 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
NPKDGBBO_01693 1.2e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NPKDGBBO_01694 4.3e-69 rplI J Binds to the 23S rRNA
NPKDGBBO_01695 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NPKDGBBO_01696 9.8e-64 S SLAP domain
NPKDGBBO_01697 4.6e-156 EGP Major facilitator Superfamily
NPKDGBBO_01698 1.7e-103 tnpR1 L Resolvase, N terminal domain
NPKDGBBO_01700 1.5e-223 pbuG S permease
NPKDGBBO_01701 2.3e-35
NPKDGBBO_01702 9.3e-77 atkY K Penicillinase repressor
NPKDGBBO_01703 1.2e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NPKDGBBO_01704 1.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NPKDGBBO_01705 0.0 copA 3.6.3.54 P P-type ATPase
NPKDGBBO_01706 2.2e-36 EGP Sugar (and other) transporter
NPKDGBBO_01707 1.9e-121 EGP Sugar (and other) transporter
NPKDGBBO_01708 1.2e-18
NPKDGBBO_01709 1.7e-212
NPKDGBBO_01710 8.4e-290 clcA P chloride
NPKDGBBO_01711 2.2e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPKDGBBO_01712 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPKDGBBO_01713 5.6e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPKDGBBO_01714 6.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPKDGBBO_01715 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPKDGBBO_01716 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NPKDGBBO_01717 6.8e-259 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPKDGBBO_01718 3.9e-196 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPKDGBBO_01719 1.3e-34 yaaA S S4 domain protein YaaA
NPKDGBBO_01720 4e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPKDGBBO_01721 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPKDGBBO_01722 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPKDGBBO_01723 1.1e-277 mycA 4.2.1.53 S Myosin-crossreactive antigen
NPKDGBBO_01724 1.3e-109 S SNARE associated Golgi protein
NPKDGBBO_01725 8.8e-203 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NPKDGBBO_01726 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
NPKDGBBO_01727 1.9e-26 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NPKDGBBO_01728 3.7e-23 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NPKDGBBO_01729 1.9e-212 yubA S AI-2E family transporter
NPKDGBBO_01730 5.5e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPKDGBBO_01731 1.4e-68 WQ51_03320 S Protein of unknown function (DUF1149)
NPKDGBBO_01732 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NPKDGBBO_01733 1.8e-226 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
NPKDGBBO_01734 1e-237 S Peptidase M16
NPKDGBBO_01735 1e-133 IQ Enoyl-(Acyl carrier protein) reductase
NPKDGBBO_01736 1.6e-144 ymfM S Helix-turn-helix domain
NPKDGBBO_01737 2.5e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPKDGBBO_01738 5.5e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPKDGBBO_01739 9.5e-220 rny S Endoribonuclease that initiates mRNA decay
NPKDGBBO_01740 1.6e-208 tagO 2.7.8.33, 2.7.8.35 M transferase
NPKDGBBO_01741 1.3e-117 yvyE 3.4.13.9 S YigZ family
NPKDGBBO_01742 3.9e-248 comFA L Helicase C-terminal domain protein
NPKDGBBO_01743 2.6e-134 comFC S Competence protein
NPKDGBBO_01744 2.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPKDGBBO_01745 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPKDGBBO_01746 2.3e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPKDGBBO_01747 5.1e-19
NPKDGBBO_01748 7.6e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPKDGBBO_01749 3.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPKDGBBO_01751 1.2e-115 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NPKDGBBO_01752 3.4e-21 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NPKDGBBO_01753 1.4e-193 ydiM G Major Facilitator Superfamily
NPKDGBBO_01754 3.6e-137 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NPKDGBBO_01755 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NPKDGBBO_01756 1.3e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NPKDGBBO_01757 3.9e-220 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NPKDGBBO_01758 1.1e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NPKDGBBO_01759 1.3e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPKDGBBO_01760 8.8e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPKDGBBO_01761 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPKDGBBO_01762 2.4e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NPKDGBBO_01763 4.9e-201 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NPKDGBBO_01764 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NPKDGBBO_01765 4.3e-244 purD 6.3.4.13 F Belongs to the GARS family
NPKDGBBO_01766 3.4e-211 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPKDGBBO_01767 2.9e-144 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPKDGBBO_01768 4.9e-185 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPKDGBBO_01769 1.3e-201 oppD P Belongs to the ABC transporter superfamily
NPKDGBBO_01770 3.2e-175 oppF P Belongs to the ABC transporter superfamily
NPKDGBBO_01771 1.8e-256 pepC 3.4.22.40 E aminopeptidase
NPKDGBBO_01772 4.7e-60 hsp O Belongs to the small heat shock protein (HSP20) family
NPKDGBBO_01773 1.9e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPKDGBBO_01774 6.4e-114
NPKDGBBO_01776 5.3e-115 E Belongs to the SOS response-associated peptidase family
NPKDGBBO_01777 2.8e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPKDGBBO_01778 1.5e-91 comEB 3.5.4.12 F MafB19-like deaminase
NPKDGBBO_01779 1.3e-106 S TPM domain
NPKDGBBO_01780 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NPKDGBBO_01781 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPKDGBBO_01782 4.6e-148 tatD L hydrolase, TatD family
NPKDGBBO_01783 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPKDGBBO_01784 5.5e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPKDGBBO_01785 7e-37 veg S Biofilm formation stimulator VEG
NPKDGBBO_01786 2.4e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NPKDGBBO_01787 4.2e-208 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPKDGBBO_01788 1.6e-89 S SLAP domain
NPKDGBBO_01789 3.2e-74 S SLAP domain
NPKDGBBO_01790 5.9e-68 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NPKDGBBO_01791 3.1e-66 2.4.1.83 GT2 S GtrA-like protein
NPKDGBBO_01792 3e-170 yfdH GT2 M Glycosyltransferase like family 2
NPKDGBBO_01793 7e-245 L transposase, IS605 OrfB family
NPKDGBBO_01794 9e-36
NPKDGBBO_01795 5.7e-91 res 3.1.21.5 L Type III restriction enzyme, res subunit
NPKDGBBO_01796 1e-171 L COG3547 Transposase and inactivated derivatives
NPKDGBBO_01797 4.7e-16
NPKDGBBO_01798 6.9e-12
NPKDGBBO_01799 5.2e-134 L PFAM transposase, IS4 family protein
NPKDGBBO_01800 9.8e-139 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NPKDGBBO_01801 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
NPKDGBBO_01802 1e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
NPKDGBBO_01803 6.8e-159 psaA P Belongs to the bacterial solute-binding protein 9 family
NPKDGBBO_01804 2.5e-118 fhuC P ABC transporter
NPKDGBBO_01805 1.1e-131 znuB U ABC 3 transport family
NPKDGBBO_01806 1.6e-239 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPKDGBBO_01808 6.2e-67 msmR7 K helix_turn_helix, arabinose operon control protein
NPKDGBBO_01809 3.4e-36 rafA 3.2.1.22 G alpha-galactosidase
NPKDGBBO_01810 3.6e-188 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NPKDGBBO_01811 1.4e-134 manY G PTS system
NPKDGBBO_01812 1.2e-174 manN G system, mannose fructose sorbose family IID component
NPKDGBBO_01813 7.6e-64 manO S Domain of unknown function (DUF956)
NPKDGBBO_01814 9.1e-150 K Transcriptional regulator
NPKDGBBO_01815 4e-10 maa S transferase hexapeptide repeat
NPKDGBBO_01816 3.7e-61 maa S transferase hexapeptide repeat
NPKDGBBO_01817 5.8e-242 cycA E Amino acid permease
NPKDGBBO_01818 9.6e-124 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NPKDGBBO_01819 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NPKDGBBO_01820 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPKDGBBO_01821 8.8e-47
NPKDGBBO_01822 2.2e-45 yagE E amino acid
NPKDGBBO_01823 2.8e-49
NPKDGBBO_01824 9.6e-89 UW LPXTG-motif cell wall anchor domain protein
NPKDGBBO_01825 4.7e-35 S LPXTG cell wall anchor motif
NPKDGBBO_01827 5.4e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPKDGBBO_01828 3.1e-104 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NPKDGBBO_01829 6.2e-134 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NPKDGBBO_01830 3.4e-86 S ECF transporter, substrate-specific component
NPKDGBBO_01831 1.6e-142 fat 3.1.2.21 I Acyl-ACP thioesterase
NPKDGBBO_01832 7.9e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPKDGBBO_01833 2.4e-59 yabA L Involved in initiation control of chromosome replication
NPKDGBBO_01834 1.5e-155 holB 2.7.7.7 L DNA polymerase III
NPKDGBBO_01835 2.2e-51 yaaQ S Cyclic-di-AMP receptor
NPKDGBBO_01836 8.7e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPKDGBBO_01837 6.4e-35 S Protein of unknown function (DUF2508)
NPKDGBBO_01838 4.8e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPKDGBBO_01839 5e-38 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPKDGBBO_01840 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPKDGBBO_01841 6.9e-92 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPKDGBBO_01842 1e-116 rsmC 2.1.1.172 J Methyltransferase
NPKDGBBO_01843 1.1e-80 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
NPKDGBBO_01844 2.4e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPKDGBBO_01845 5.4e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPKDGBBO_01846 1.8e-157 yfdV S Membrane transport protein
NPKDGBBO_01847 4.3e-27 yfdV S Membrane transport protein
NPKDGBBO_01848 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
NPKDGBBO_01849 3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPKDGBBO_01850 1.1e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPKDGBBO_01851 7e-156 pstA P Phosphate transport system permease protein PstA
NPKDGBBO_01852 3.7e-174 pstC P probably responsible for the translocation of the substrate across the membrane
NPKDGBBO_01853 4.3e-158 pstS P Phosphate
NPKDGBBO_01854 2.4e-36 L An automated process has identified a potential problem with this gene model
NPKDGBBO_01855 4.6e-196 ampC V Beta-lactamase
NPKDGBBO_01858 5.8e-64
NPKDGBBO_01860 4.5e-255 S Virulence-associated protein E
NPKDGBBO_01862 9.4e-43
NPKDGBBO_01863 1.7e-29
NPKDGBBO_01865 6.8e-82 K Transcriptional
NPKDGBBO_01866 2.3e-223 sip L Belongs to the 'phage' integrase family
NPKDGBBO_01867 3.1e-248 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NPKDGBBO_01868 7.6e-114 tdk 2.7.1.21 F thymidine kinase
NPKDGBBO_01869 5.3e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPKDGBBO_01870 6e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPKDGBBO_01871 1.1e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPKDGBBO_01872 3e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPKDGBBO_01873 7.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NPKDGBBO_01874 8.6e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPKDGBBO_01875 9.5e-49 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPKDGBBO_01876 2.3e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPKDGBBO_01877 2.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPKDGBBO_01878 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPKDGBBO_01879 2.4e-238 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPKDGBBO_01880 7.7e-55 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NPKDGBBO_01881 3.4e-30 ywzB S Protein of unknown function (DUF1146)
NPKDGBBO_01882 6.5e-179 mbl D Cell shape determining protein MreB Mrl
NPKDGBBO_01883 3.8e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NPKDGBBO_01884 8.6e-34 S Protein of unknown function (DUF2969)
NPKDGBBO_01885 1.5e-217 rodA D Belongs to the SEDS family
NPKDGBBO_01886 3.1e-78 usp6 T universal stress protein
NPKDGBBO_01887 2.5e-35
NPKDGBBO_01888 7.2e-242 rarA L recombination factor protein RarA
NPKDGBBO_01889 2.7e-82 yueI S Protein of unknown function (DUF1694)
NPKDGBBO_01890 1.8e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPKDGBBO_01891 2.7e-281 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPKDGBBO_01892 4.2e-217 iscS2 2.8.1.7 E Aminotransferase class V
NPKDGBBO_01893 1.7e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPKDGBBO_01894 3.7e-141 K Helix-turn-helix domain
NPKDGBBO_01895 4.9e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPKDGBBO_01896 2e-14 K Helix-turn-helix XRE-family like proteins
NPKDGBBO_01897 1.1e-65
NPKDGBBO_01898 1.4e-95
NPKDGBBO_01899 1e-90
NPKDGBBO_01900 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPKDGBBO_01901 1.3e-165 dnaI L Primosomal protein DnaI
NPKDGBBO_01902 2.1e-249 dnaB L Replication initiation and membrane attachment
NPKDGBBO_01903 6e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPKDGBBO_01904 4.5e-106 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPKDGBBO_01905 5.3e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPKDGBBO_01906 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPKDGBBO_01907 1.6e-12
NPKDGBBO_01910 7.1e-34
NPKDGBBO_01911 9.2e-09 S Hypothetical protein (DUF2513)
NPKDGBBO_01912 1.7e-57 V Type II restriction enzyme, methylase subunits
NPKDGBBO_01914 4.5e-49 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPKDGBBO_01915 5.5e-62 S Protein of unknown function (DUF2974)
NPKDGBBO_01916 2.8e-109 glnP P ABC transporter permease
NPKDGBBO_01917 6.7e-108 gluC P ABC transporter permease
NPKDGBBO_01918 1.5e-152 glnH ET ABC transporter substrate-binding protein
NPKDGBBO_01919 3.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPKDGBBO_01920 6.3e-28 rimL J Acetyltransferase (GNAT) domain
NPKDGBBO_01921 5.6e-55 rimL J Acetyltransferase (GNAT) domain
NPKDGBBO_01922 5e-55
NPKDGBBO_01923 7.1e-289 S ABC transporter
NPKDGBBO_01924 6.1e-140 thrE S Putative threonine/serine exporter
NPKDGBBO_01925 1.5e-83 S Threonine/Serine exporter, ThrE
NPKDGBBO_01926 1.3e-122 yvpB S Peptidase_C39 like family
NPKDGBBO_01927 2e-172 yjeM E Amino Acid
NPKDGBBO_01928 5.2e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPKDGBBO_01929 8.4e-33 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
NPKDGBBO_01930 2.6e-08 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
NPKDGBBO_01932 6.5e-90
NPKDGBBO_01934 1.2e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NPKDGBBO_01937 7.9e-70 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NPKDGBBO_01938 4.2e-197 pbpX1 V Beta-lactamase
NPKDGBBO_01939 0.0 L Helicase C-terminal domain protein
NPKDGBBO_01940 5.7e-144 E amino acid
NPKDGBBO_01941 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
NPKDGBBO_01942 1.4e-169 yniA G Phosphotransferase enzyme family
NPKDGBBO_01943 3.1e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPKDGBBO_01944 4e-43 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NPKDGBBO_01945 8.5e-90 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NPKDGBBO_01946 7.7e-134 tetP J elongation factor G
NPKDGBBO_01947 7.5e-222 tetP J elongation factor G
NPKDGBBO_01948 3.6e-165 yvgN C Aldo keto reductase
NPKDGBBO_01949 2.4e-59 S SLAP domain
NPKDGBBO_01950 7.5e-86 S SLAP domain
NPKDGBBO_01951 1.5e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NPKDGBBO_01952 1.6e-177 ABC-SBP S ABC transporter
NPKDGBBO_01953 2.9e-122 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NPKDGBBO_01954 9.6e-138 XK27_08845 S ABC transporter, ATP-binding protein
NPKDGBBO_01955 4.1e-41
NPKDGBBO_01956 4.8e-11
NPKDGBBO_01957 6.2e-105 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
NPKDGBBO_01958 2.2e-177 K AI-2E family transporter
NPKDGBBO_01959 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
NPKDGBBO_01960 2.1e-67 S Domain of unknown function (DUF4430)
NPKDGBBO_01961 1.4e-87 S ECF transporter, substrate-specific component
NPKDGBBO_01962 1.3e-99 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
NPKDGBBO_01963 3.6e-134 yvdE K helix_turn _helix lactose operon repressor
NPKDGBBO_01964 1e-41 L Helix-turn-helix domain
NPKDGBBO_01965 2.4e-223 oxlT P Major Facilitator Superfamily
NPKDGBBO_01967 1.6e-252 hsdM 2.1.1.72 V type I restriction-modification system
NPKDGBBO_01968 1.4e-100 3.1.21.3 V Type I restriction modification DNA specificity domain
NPKDGBBO_01970 1.5e-132 mrr L restriction endonuclease
NPKDGBBO_01972 3.8e-218 S SLAP domain
NPKDGBBO_01973 7.4e-15 S YSIRK type signal peptide
NPKDGBBO_01974 1.4e-68 UW LPXTG-motif cell wall anchor domain protein
NPKDGBBO_01976 2.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPKDGBBO_01977 1.2e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPKDGBBO_01978 7e-206 csaB M Glycosyl transferases group 1
NPKDGBBO_01979 8.6e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NPKDGBBO_01980 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPKDGBBO_01981 4.6e-132
NPKDGBBO_01982 3e-118
NPKDGBBO_01983 7.5e-180 S Oxidoreductase family, NAD-binding Rossmann fold
NPKDGBBO_01984 2e-115 gepA K Protein of unknown function (DUF4065)
NPKDGBBO_01985 0.0 yjbQ P TrkA C-terminal domain protein
NPKDGBBO_01986 1.1e-206 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NPKDGBBO_01987 3.7e-208 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPKDGBBO_01988 3.1e-37
NPKDGBBO_01990 1.8e-176 S SLAP domain
NPKDGBBO_01991 4.1e-35 S Protein of unknown function (DUF2922)
NPKDGBBO_01992 7.9e-29
NPKDGBBO_01995 7.5e-86
NPKDGBBO_01996 0.0 kup P Transport of potassium into the cell
NPKDGBBO_01997 8.2e-53 V Type II restriction enzyme, methylase subunits
NPKDGBBO_01998 3.5e-104 V Type II restriction enzyme, methylase subunits
NPKDGBBO_01999 1.1e-88 V Type II restriction enzyme, methylase subunits
NPKDGBBO_02002 6.6e-56 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
NPKDGBBO_02003 9.8e-288 hsdM 2.1.1.72 V type I restriction-modification system
NPKDGBBO_02004 6.1e-216 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
NPKDGBBO_02005 4.5e-216 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
NPKDGBBO_02006 4.4e-149 hsdS2 2.1.1.72 L N-6 DNA Methylase
NPKDGBBO_02007 1.9e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPKDGBBO_02008 1.9e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NPKDGBBO_02009 2e-156 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPKDGBBO_02010 2.7e-85 S Aminoacyl-tRNA editing domain
NPKDGBBO_02011 3.2e-281 arlS 2.7.13.3 T Histidine kinase
NPKDGBBO_02012 3.2e-127 K response regulator
NPKDGBBO_02013 4.1e-98 yceD S Uncharacterized ACR, COG1399
NPKDGBBO_02014 1.7e-215 ylbM S Belongs to the UPF0348 family
NPKDGBBO_02015 6.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPKDGBBO_02016 2.3e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NPKDGBBO_02017 1.2e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPKDGBBO_02018 1.3e-212 yqeH S Ribosome biogenesis GTPase YqeH
NPKDGBBO_02019 1.3e-93 yqeG S HAD phosphatase, family IIIA
NPKDGBBO_02020 5.1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPKDGBBO_02021 6.2e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NPKDGBBO_02022 1.5e-56 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPKDGBBO_02023 4e-237 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
NPKDGBBO_02024 3.5e-29 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
NPKDGBBO_02025 2e-185 S Domain of unknown function (DUF389)
NPKDGBBO_02026 1.1e-46 S ACT domain
NPKDGBBO_02027 5.5e-97 yxkA S Phosphatidylethanolamine-binding protein
NPKDGBBO_02028 4e-248 yjjP S Putative threonine/serine exporter
NPKDGBBO_02029 5.3e-178 citR K Putative sugar-binding domain
NPKDGBBO_02030 1.6e-52
NPKDGBBO_02031 1.6e-16
NPKDGBBO_02032 6.4e-66 S Domain of unknown function DUF1828
NPKDGBBO_02033 5.6e-95 S UPF0397 protein
NPKDGBBO_02034 0.0 ykoD P ABC transporter, ATP-binding protein
NPKDGBBO_02035 4.3e-147 cbiQ P cobalt transport
NPKDGBBO_02036 2.7e-10
NPKDGBBO_02037 2.7e-71 yeaL S Protein of unknown function (DUF441)
NPKDGBBO_02038 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NPKDGBBO_02039 3.5e-25
NPKDGBBO_02041 5.3e-145 glcU U sugar transport
NPKDGBBO_02042 1e-60 L Transposase
NPKDGBBO_02043 1.2e-202 lsa S ABC transporter
NPKDGBBO_02044 2.1e-102 S LexA-binding, inner membrane-associated putative hydrolase
NPKDGBBO_02045 3.4e-22
NPKDGBBO_02046 1.1e-92 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NPKDGBBO_02048 1.3e-104 E GDSL-like Lipase/Acylhydrolase
NPKDGBBO_02049 2.2e-78 yjcF S Acetyltransferase (GNAT) domain
NPKDGBBO_02050 6.1e-151 aatB ET ABC transporter substrate-binding protein
NPKDGBBO_02051 4.5e-109 glnQ 3.6.3.21 E ABC transporter
NPKDGBBO_02052 4.7e-109 glnP P ABC transporter permease
NPKDGBBO_02053 0.0 helD 3.6.4.12 L DNA helicase
NPKDGBBO_02054 6.5e-120 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NPKDGBBO_02055 1.3e-34 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPKDGBBO_02056 4.5e-35 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPKDGBBO_02057 2.7e-176 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
NPKDGBBO_02058 1.4e-92 P Cobalt transport protein
NPKDGBBO_02059 1.9e-250 cbiO1 S ABC transporter, ATP-binding protein
NPKDGBBO_02060 5.1e-173 K helix_turn_helix, arabinose operon control protein
NPKDGBBO_02061 4.1e-59 L hmm pf00665
NPKDGBBO_02062 5.6e-08 L hmm pf00665
NPKDGBBO_02063 1.8e-19 L hmm pf00665
NPKDGBBO_02064 1.8e-65 L Helix-turn-helix domain
NPKDGBBO_02065 1.3e-162 htpX O Belongs to the peptidase M48B family
NPKDGBBO_02066 2.3e-96 lemA S LemA family
NPKDGBBO_02067 3.6e-194 ybiR P Citrate transporter
NPKDGBBO_02068 5.9e-70 S Iron-sulphur cluster biosynthesis
NPKDGBBO_02069 4.2e-19 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NPKDGBBO_02070 1.2e-17
NPKDGBBO_02071 1e-151
NPKDGBBO_02072 2.8e-166 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPKDGBBO_02073 4.4e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPKDGBBO_02074 3.2e-15
NPKDGBBO_02075 8.6e-116 sip L Belongs to the 'phage' integrase family
NPKDGBBO_02076 3.9e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPKDGBBO_02077 2.9e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPKDGBBO_02078 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPKDGBBO_02079 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPKDGBBO_02080 7e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPKDGBBO_02081 6.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPKDGBBO_02082 7.5e-39 yajC U Preprotein translocase
NPKDGBBO_02083 1.1e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NPKDGBBO_02084 7.1e-214 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPKDGBBO_02085 1.6e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NPKDGBBO_02086 1.3e-230 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPKDGBBO_02087 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPKDGBBO_02088 2e-42 yrzL S Belongs to the UPF0297 family
NPKDGBBO_02089 3.6e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPKDGBBO_02090 6.2e-51 yrzB S Belongs to the UPF0473 family
NPKDGBBO_02091 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPKDGBBO_02092 4.6e-54 trxA O Belongs to the thioredoxin family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)