ORF_ID e_value Gene_name EC_number CAZy COGs Description
IPCOMLNL_00001 8.5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
IPCOMLNL_00002 7.3e-09
IPCOMLNL_00003 2.4e-220 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IPCOMLNL_00004 6.8e-15
IPCOMLNL_00008 4.1e-20 S HNH endonuclease
IPCOMLNL_00012 1.3e-254 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IPCOMLNL_00013 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IPCOMLNL_00014 3e-280 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
IPCOMLNL_00015 7.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
IPCOMLNL_00016 7.7e-109 yttP K Transcriptional regulator
IPCOMLNL_00017 7.8e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IPCOMLNL_00018 8.6e-264 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IPCOMLNL_00019 4e-240 braB E Component of the transport system for branched-chain amino acids
IPCOMLNL_00020 1.4e-209 iscS2 2.8.1.7 E Cysteine desulfurase
IPCOMLNL_00021 6.6e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IPCOMLNL_00022 3.9e-31 sspB S spore protein
IPCOMLNL_00023 1.1e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IPCOMLNL_00024 0.0 ytcJ S amidohydrolase
IPCOMLNL_00025 7e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IPCOMLNL_00026 6.4e-182 sppA OU signal peptide peptidase SppA
IPCOMLNL_00027 1.4e-86 yteJ S RDD family
IPCOMLNL_00028 2.7e-107 ytfI S Protein of unknown function (DUF2953)
IPCOMLNL_00029 1.6e-60 ytfJ S Sporulation protein YtfJ
IPCOMLNL_00030 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IPCOMLNL_00031 4.4e-183 ytxK 2.1.1.72 L DNA methylase
IPCOMLNL_00032 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPCOMLNL_00033 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
IPCOMLNL_00034 2.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IPCOMLNL_00035 9.2e-264 argH 4.3.2.1 E argininosuccinate lyase
IPCOMLNL_00037 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCOMLNL_00038 2.5e-129 ytkL S Belongs to the UPF0173 family
IPCOMLNL_00039 2.8e-238 ytoI K transcriptional regulator containing CBS domains
IPCOMLNL_00040 5.3e-47 ytpI S YtpI-like protein
IPCOMLNL_00041 2.7e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
IPCOMLNL_00042 1.5e-23
IPCOMLNL_00043 5.1e-87 ytrI
IPCOMLNL_00044 9.2e-56 ytrH S Sporulation protein YtrH
IPCOMLNL_00045 0.0 dnaE 2.7.7.7 L DNA polymerase
IPCOMLNL_00046 7.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
IPCOMLNL_00047 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IPCOMLNL_00048 4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IPCOMLNL_00049 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IPCOMLNL_00050 2.2e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IPCOMLNL_00051 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
IPCOMLNL_00052 4.8e-194 ytvI S sporulation integral membrane protein YtvI
IPCOMLNL_00053 9.5e-72 yeaL S membrane
IPCOMLNL_00054 2.5e-47 yjdF S Protein of unknown function (DUF2992)
IPCOMLNL_00055 7.1e-53
IPCOMLNL_00056 2.2e-199 S Aspartate phosphatase response regulator
IPCOMLNL_00058 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
IPCOMLNL_00059 9.1e-242 icd 1.1.1.42 C isocitrate
IPCOMLNL_00060 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
IPCOMLNL_00061 3.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCOMLNL_00062 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
IPCOMLNL_00063 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPCOMLNL_00064 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IPCOMLNL_00065 9.5e-107 ytaF P Probably functions as a manganese efflux pump
IPCOMLNL_00066 6.4e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IPCOMLNL_00067 1.7e-159 ytbE S reductase
IPCOMLNL_00068 4.5e-206 ytbD EGP Major facilitator Superfamily
IPCOMLNL_00069 2e-67 ytcD K Transcriptional regulator
IPCOMLNL_00070 8.8e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IPCOMLNL_00071 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IPCOMLNL_00072 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IPCOMLNL_00073 2.9e-257 dnaB L Membrane attachment protein
IPCOMLNL_00074 4.3e-172 dnaI L Primosomal protein DnaI
IPCOMLNL_00075 6e-109 ytxB S SNARE associated Golgi protein
IPCOMLNL_00076 3e-153 ytxC S YtxC-like family
IPCOMLNL_00077 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPCOMLNL_00078 1e-150 ysaA S HAD-hyrolase-like
IPCOMLNL_00079 0.0 lytS 2.7.13.3 T Histidine kinase
IPCOMLNL_00080 1.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
IPCOMLNL_00081 9.1e-40 lrgA S effector of murein hydrolase LrgA
IPCOMLNL_00082 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IPCOMLNL_00083 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IPCOMLNL_00084 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IPCOMLNL_00085 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IPCOMLNL_00086 7e-43 ysdA S Membrane
IPCOMLNL_00087 1.7e-66 ysdB S Sigma-w pathway protein YsdB
IPCOMLNL_00088 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
IPCOMLNL_00089 9.8e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IPCOMLNL_00090 8.9e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IPCOMLNL_00091 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
IPCOMLNL_00092 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IPCOMLNL_00093 7.1e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
IPCOMLNL_00094 9.8e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IPCOMLNL_00095 1.7e-251 araN G carbohydrate transport
IPCOMLNL_00096 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
IPCOMLNL_00097 9.9e-144 araQ G transport system permease
IPCOMLNL_00098 1.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
IPCOMLNL_00099 0.0 cstA T Carbon starvation protein
IPCOMLNL_00100 2.4e-253 glcF C Glycolate oxidase
IPCOMLNL_00101 3.7e-260 glcD 1.1.3.15 C FAD binding domain
IPCOMLNL_00102 8.4e-204 ysfB KT regulator
IPCOMLNL_00103 2e-32 sspI S Belongs to the SspI family
IPCOMLNL_00104 1.4e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPCOMLNL_00105 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IPCOMLNL_00106 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IPCOMLNL_00107 4.2e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPCOMLNL_00108 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IPCOMLNL_00109 1.1e-82 cvpA S membrane protein, required for colicin V production
IPCOMLNL_00110 0.0 polX L COG1796 DNA polymerase IV (family X)
IPCOMLNL_00111 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IPCOMLNL_00112 4.7e-67 yshE S membrane
IPCOMLNL_00113 1.9e-121 ywbB S Protein of unknown function (DUF2711)
IPCOMLNL_00114 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IPCOMLNL_00115 9.2e-104 fadR K Transcriptional regulator
IPCOMLNL_00116 2.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IPCOMLNL_00117 2e-138 etfB C Electron transfer flavoprotein
IPCOMLNL_00118 3.5e-177 etfA C Electron transfer flavoprotein
IPCOMLNL_00119 1.2e-298 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
IPCOMLNL_00120 2.5e-52 trxA O Belongs to the thioredoxin family
IPCOMLNL_00121 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IPCOMLNL_00122 2.7e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IPCOMLNL_00123 1.2e-79 yslB S Protein of unknown function (DUF2507)
IPCOMLNL_00124 4.8e-108 sdhC C succinate dehydrogenase
IPCOMLNL_00125 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IPCOMLNL_00126 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IPCOMLNL_00127 3.2e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
IPCOMLNL_00128 2e-30 gerE K Transcriptional regulator
IPCOMLNL_00129 4.8e-73 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
IPCOMLNL_00130 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IPCOMLNL_00131 8.1e-199 gerM S COG5401 Spore germination protein
IPCOMLNL_00132 2e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IPCOMLNL_00133 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IPCOMLNL_00134 9.4e-89 ysnB S Phosphoesterase
IPCOMLNL_00139 0.0 ilvB 2.2.1.6 E Acetolactate synthase
IPCOMLNL_00140 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
IPCOMLNL_00141 1.2e-191 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IPCOMLNL_00142 1.8e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IPCOMLNL_00143 1.4e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IPCOMLNL_00144 3.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IPCOMLNL_00145 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IPCOMLNL_00146 3.9e-187 ysoA H Tetratricopeptide repeat
IPCOMLNL_00147 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IPCOMLNL_00148 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IPCOMLNL_00149 6e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
IPCOMLNL_00150 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IPCOMLNL_00151 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
IPCOMLNL_00152 8.5e-87 ysxD
IPCOMLNL_00153 4.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IPCOMLNL_00154 3.6e-146 hemX O cytochrome C
IPCOMLNL_00155 2.4e-175 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IPCOMLNL_00156 5e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IPCOMLNL_00157 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
IPCOMLNL_00158 1.8e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IPCOMLNL_00159 6.3e-225 spoVID M stage VI sporulation protein D
IPCOMLNL_00160 3.3e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IPCOMLNL_00161 2.1e-25
IPCOMLNL_00162 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IPCOMLNL_00163 1.9e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IPCOMLNL_00164 3.3e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IPCOMLNL_00165 8.7e-139 spoIIB S Sporulation related domain
IPCOMLNL_00166 2.4e-101 maf D septum formation protein Maf
IPCOMLNL_00167 1.8e-127 radC E Belongs to the UPF0758 family
IPCOMLNL_00168 4e-184 mreB D Rod shape-determining protein MreB
IPCOMLNL_00169 1.2e-157 mreC M Involved in formation and maintenance of cell shape
IPCOMLNL_00170 5.4e-84 mreD M shape-determining protein
IPCOMLNL_00171 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IPCOMLNL_00172 2.3e-142 minD D Belongs to the ParA family
IPCOMLNL_00173 1.9e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
IPCOMLNL_00174 2.7e-160 spoIVFB S Stage IV sporulation protein
IPCOMLNL_00175 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
IPCOMLNL_00176 3.2e-56 ysxB J ribosomal protein
IPCOMLNL_00177 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IPCOMLNL_00178 3.3e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
IPCOMLNL_00179 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IPCOMLNL_00180 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
IPCOMLNL_00181 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
IPCOMLNL_00182 5.5e-95 niaR S small molecule binding protein (contains 3H domain)
IPCOMLNL_00183 9.5e-222 nifS 2.8.1.7 E Cysteine desulfurase
IPCOMLNL_00184 9e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
IPCOMLNL_00185 6.9e-153 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
IPCOMLNL_00186 3e-209 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IPCOMLNL_00187 5.7e-145 safA M spore coat assembly protein SafA
IPCOMLNL_00188 1.4e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IPCOMLNL_00190 3.7e-93 bofC S BofC C-terminal domain
IPCOMLNL_00191 6.5e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IPCOMLNL_00192 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IPCOMLNL_00193 1.6e-20 yrzS S Protein of unknown function (DUF2905)
IPCOMLNL_00194 2.4e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IPCOMLNL_00195 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IPCOMLNL_00196 5.6e-37 yajC U Preprotein translocase subunit YajC
IPCOMLNL_00197 2.4e-60 yrzE S Protein of unknown function (DUF3792)
IPCOMLNL_00198 3.1e-108 yrbG S membrane
IPCOMLNL_00199 1.2e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPCOMLNL_00200 3.8e-50 yrzD S Post-transcriptional regulator
IPCOMLNL_00201 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPCOMLNL_00202 2.8e-85 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
IPCOMLNL_00203 5.7e-47 yrvD S Lipopolysaccharide assembly protein A domain
IPCOMLNL_00204 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IPCOMLNL_00205 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IPCOMLNL_00206 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IPCOMLNL_00207 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IPCOMLNL_00208 5.3e-276 lytH 3.5.1.28 M COG3103 SH3 domain protein
IPCOMLNL_00211 9.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
IPCOMLNL_00212 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IPCOMLNL_00213 8.2e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IPCOMLNL_00214 1.3e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IPCOMLNL_00215 2.3e-63 cymR K Transcriptional regulator
IPCOMLNL_00216 1.8e-212 iscS 2.8.1.7 E Cysteine desulfurase
IPCOMLNL_00217 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IPCOMLNL_00218 1.7e-18 S COG0457 FOG TPR repeat
IPCOMLNL_00219 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IPCOMLNL_00220 5.3e-83 yrrD S protein conserved in bacteria
IPCOMLNL_00221 2.9e-30 yrzR
IPCOMLNL_00222 2.1e-08 S Protein of unknown function (DUF3918)
IPCOMLNL_00223 1.3e-106 glnP P ABC transporter
IPCOMLNL_00224 8e-109 gluC P ABC transporter
IPCOMLNL_00225 3.2e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
IPCOMLNL_00226 4.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IPCOMLNL_00227 7e-163 yrrI S AI-2E family transporter
IPCOMLNL_00228 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPCOMLNL_00229 8.5e-41 yrzL S Belongs to the UPF0297 family
IPCOMLNL_00230 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IPCOMLNL_00231 7.1e-46 yrzB S Belongs to the UPF0473 family
IPCOMLNL_00232 4.4e-184 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IPCOMLNL_00233 3.6e-117 yrrM 2.1.1.104 S O-methyltransferase
IPCOMLNL_00234 1.7e-173 yegQ O Peptidase U32
IPCOMLNL_00235 7.9e-246 yegQ O COG0826 Collagenase and related proteases
IPCOMLNL_00236 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
IPCOMLNL_00237 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IPCOMLNL_00238 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
IPCOMLNL_00239 8.9e-69 yrrS S Protein of unknown function (DUF1510)
IPCOMLNL_00240 4.1e-27 yrzA S Protein of unknown function (DUF2536)
IPCOMLNL_00241 6.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
IPCOMLNL_00242 1.1e-121 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IPCOMLNL_00243 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
IPCOMLNL_00244 3.7e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IPCOMLNL_00245 4.6e-35 yrhC S YrhC-like protein
IPCOMLNL_00246 4.5e-80 yrhD S Protein of unknown function (DUF1641)
IPCOMLNL_00247 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
IPCOMLNL_00248 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
IPCOMLNL_00249 8e-143 focA P Formate nitrite
IPCOMLNL_00251 3.9e-93 yrhH Q methyltransferase
IPCOMLNL_00252 7.7e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
IPCOMLNL_00253 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IPCOMLNL_00254 1.4e-212 ynfM EGP Major facilitator Superfamily
IPCOMLNL_00255 2e-163 yybE K Transcriptional regulator
IPCOMLNL_00256 2.1e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IPCOMLNL_00257 2.6e-182 romA S Beta-lactamase superfamily domain
IPCOMLNL_00258 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
IPCOMLNL_00259 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
IPCOMLNL_00260 1.8e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
IPCOMLNL_00261 1.6e-129 glvR K Helix-turn-helix domain, rpiR family
IPCOMLNL_00262 5.1e-145 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
IPCOMLNL_00263 2e-146 S hydrolase
IPCOMLNL_00265 1.5e-91 yrdA S DinB family
IPCOMLNL_00266 7.4e-81 yyaR K Acetyltransferase (GNAT) domain
IPCOMLNL_00268 6.4e-39
IPCOMLNL_00270 3.3e-22 S Uncharacterized protein conserved in bacteria (DUF2188)
IPCOMLNL_00271 5.7e-15
IPCOMLNL_00272 1.1e-67
IPCOMLNL_00273 8.1e-117 L nucleic acid phosphodiester bond hydrolysis
IPCOMLNL_00274 8.8e-57 S SMI1-KNR4 cell-wall
IPCOMLNL_00277 7.3e-221 tetL EGP Major facilitator Superfamily
IPCOMLNL_00278 3.6e-29 yyaR K acetyltransferase
IPCOMLNL_00279 2e-97 adk 2.7.4.3 F adenylate kinase activity
IPCOMLNL_00280 6.2e-102 yrkN K Acetyltransferase (GNAT) family
IPCOMLNL_00281 2.9e-221 yrkO P Protein of unknown function (DUF418)
IPCOMLNL_00282 1.6e-123 T Transcriptional regulator
IPCOMLNL_00283 4.6e-233 yrkQ T Histidine kinase
IPCOMLNL_00284 3e-69 psiE S Belongs to the PsiE family
IPCOMLNL_00285 1.3e-123 yecA E amino acid
IPCOMLNL_00286 3.9e-106 K Transcriptional regulator
IPCOMLNL_00287 6.2e-149 ydeE K AraC family transcriptional regulator
IPCOMLNL_00289 2.2e-20 S SMI1-KNR4 cell-wall
IPCOMLNL_00290 7.1e-195 yobL S Bacterial EndoU nuclease
IPCOMLNL_00291 4.1e-21 V HNH endonuclease
IPCOMLNL_00292 3.9e-70
IPCOMLNL_00293 5.9e-58
IPCOMLNL_00294 9.8e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCOMLNL_00295 6.9e-218 EGP Major facilitator Superfamily
IPCOMLNL_00296 1.6e-106 yqeD S SNARE associated Golgi protein
IPCOMLNL_00297 2.6e-140 3.5.1.104 G Polysaccharide deacetylase
IPCOMLNL_00298 8.5e-139 yqeF E GDSL-like Lipase/Acylhydrolase
IPCOMLNL_00300 2e-94 yqeG S hydrolase of the HAD superfamily
IPCOMLNL_00301 5.9e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IPCOMLNL_00302 2.4e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPCOMLNL_00303 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
IPCOMLNL_00304 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IPCOMLNL_00305 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IPCOMLNL_00306 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IPCOMLNL_00307 2.2e-139 yqeM Q Methyltransferase
IPCOMLNL_00308 1.3e-145 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPCOMLNL_00309 2.8e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
IPCOMLNL_00310 8e-105 comEB 3.5.4.12 F ComE operon protein 2
IPCOMLNL_00311 0.0 comEC S Competence protein ComEC
IPCOMLNL_00312 8.5e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
IPCOMLNL_00313 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
IPCOMLNL_00314 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IPCOMLNL_00315 1.4e-220 spoIIP M stage II sporulation protein P
IPCOMLNL_00316 3.8e-54 yqxA S Protein of unknown function (DUF3679)
IPCOMLNL_00317 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IPCOMLNL_00318 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
IPCOMLNL_00319 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IPCOMLNL_00320 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IPCOMLNL_00321 0.0 dnaK O Heat shock 70 kDa protein
IPCOMLNL_00322 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IPCOMLNL_00323 7.8e-174 prmA J Methylates ribosomal protein L11
IPCOMLNL_00324 2e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IPCOMLNL_00325 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
IPCOMLNL_00326 3.5e-158 yqeW P COG1283 Na phosphate symporter
IPCOMLNL_00327 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IPCOMLNL_00328 3.6e-68 yqeY S Yqey-like protein
IPCOMLNL_00329 2.8e-230 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
IPCOMLNL_00330 1.2e-119 yqfA S UPF0365 protein
IPCOMLNL_00331 3.8e-54 yqfB
IPCOMLNL_00332 9.3e-46 yqfC S sporulation protein YqfC
IPCOMLNL_00333 2.6e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
IPCOMLNL_00334 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
IPCOMLNL_00335 0.0 yqfF S membrane-associated HD superfamily hydrolase
IPCOMLNL_00336 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IPCOMLNL_00337 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IPCOMLNL_00338 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IPCOMLNL_00339 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IPCOMLNL_00340 1.8e-16 S YqzL-like protein
IPCOMLNL_00341 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
IPCOMLNL_00342 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IPCOMLNL_00343 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IPCOMLNL_00344 4.5e-112 ccpN K CBS domain
IPCOMLNL_00345 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IPCOMLNL_00346 6.1e-88 yaiI S Belongs to the UPF0178 family
IPCOMLNL_00347 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IPCOMLNL_00348 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IPCOMLNL_00349 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
IPCOMLNL_00350 9.9e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
IPCOMLNL_00351 2.1e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IPCOMLNL_00352 1.9e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IPCOMLNL_00353 6.2e-51 yqfQ S YqfQ-like protein
IPCOMLNL_00354 2.6e-239 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IPCOMLNL_00355 4.4e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IPCOMLNL_00356 1.6e-36 yqfT S Protein of unknown function (DUF2624)
IPCOMLNL_00357 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IPCOMLNL_00358 2.9e-72 zur P Belongs to the Fur family
IPCOMLNL_00359 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
IPCOMLNL_00360 2.3e-52 yqfX S membrane
IPCOMLNL_00361 4.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IPCOMLNL_00362 3.1e-47 yqfZ M LysM domain
IPCOMLNL_00363 8.7e-131 yqgB S Protein of unknown function (DUF1189)
IPCOMLNL_00364 5.1e-76 yqgC S protein conserved in bacteria
IPCOMLNL_00365 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
IPCOMLNL_00366 2e-228 yqgE EGP Major facilitator superfamily
IPCOMLNL_00367 0.0 pbpA 3.4.16.4 M penicillin-binding protein
IPCOMLNL_00368 1.7e-157 pstS P Phosphate
IPCOMLNL_00369 5.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
IPCOMLNL_00370 1.8e-156 pstA P Phosphate transport system permease
IPCOMLNL_00371 2.3e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IPCOMLNL_00372 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IPCOMLNL_00373 1.6e-74 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IPCOMLNL_00374 1.2e-50 yqzD
IPCOMLNL_00375 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IPCOMLNL_00376 4.1e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IPCOMLNL_00377 1.8e-07 yqgO
IPCOMLNL_00378 1.6e-231 nhaC C Na H antiporter
IPCOMLNL_00379 1e-28 yqgQ S Protein conserved in bacteria
IPCOMLNL_00380 4.9e-179 glcK 2.7.1.2 G Glucokinase
IPCOMLNL_00381 1.1e-219 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
IPCOMLNL_00382 2.3e-198 yqgU
IPCOMLNL_00383 6.9e-50 yqgV S Thiamine-binding protein
IPCOMLNL_00384 5.4e-20 yqgW S Protein of unknown function (DUF2759)
IPCOMLNL_00385 8.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IPCOMLNL_00386 3.1e-37 yqgY S Protein of unknown function (DUF2626)
IPCOMLNL_00387 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
IPCOMLNL_00389 1e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IPCOMLNL_00390 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IPCOMLNL_00391 1.5e-185 corA P Mg2 transporter protein
IPCOMLNL_00392 2.3e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPCOMLNL_00393 5.4e-184 comGB NU COG1459 Type II secretory pathway, component PulF
IPCOMLNL_00394 7.5e-49 comGC U Required for transformation and DNA binding
IPCOMLNL_00395 6.9e-72 gspH NU Tfp pilus assembly protein FimT
IPCOMLNL_00396 1.2e-20 comGE
IPCOMLNL_00397 2.3e-78 comGF U Putative Competence protein ComGF
IPCOMLNL_00398 2.5e-62 S ComG operon protein 7
IPCOMLNL_00399 2.3e-26 yqzE S YqzE-like protein
IPCOMLNL_00400 1.3e-54 yqzG S Protein of unknown function (DUF3889)
IPCOMLNL_00401 7.2e-121 yqxM
IPCOMLNL_00402 3.5e-71 sipW 3.4.21.89 U Signal peptidase
IPCOMLNL_00403 3.3e-141 tasA S Cell division protein FtsN
IPCOMLNL_00404 7.8e-55 sinR K transcriptional
IPCOMLNL_00405 1.3e-21 sinI S Anti-repressor SinI
IPCOMLNL_00406 8.4e-153 yqhG S Bacterial protein YqhG of unknown function
IPCOMLNL_00407 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IPCOMLNL_00408 1.3e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
IPCOMLNL_00409 7.9e-252 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IPCOMLNL_00410 9.8e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IPCOMLNL_00411 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
IPCOMLNL_00412 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IPCOMLNL_00413 4.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IPCOMLNL_00414 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
IPCOMLNL_00415 3.4e-62 yqhP
IPCOMLNL_00416 1.5e-172 yqhQ S Protein of unknown function (DUF1385)
IPCOMLNL_00417 4.9e-88 yqhR S Conserved membrane protein YqhR
IPCOMLNL_00418 5.6e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IPCOMLNL_00419 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IPCOMLNL_00420 1.8e-36 yqhV S Protein of unknown function (DUF2619)
IPCOMLNL_00421 3.2e-172 spoIIIAA S stage III sporulation protein AA
IPCOMLNL_00422 1.7e-85 spoIIIAB S Stage III sporulation protein
IPCOMLNL_00423 7.6e-29 spoIIIAC S stage III sporulation protein AC
IPCOMLNL_00424 2.5e-41 spoIIIAD S Stage III sporulation protein AD
IPCOMLNL_00425 6.3e-200 spoIIIAE S stage III sporulation protein AE
IPCOMLNL_00426 5.9e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
IPCOMLNL_00427 1e-117 spoIIIAG S stage III sporulation protein AG
IPCOMLNL_00428 2.5e-62 spoIIIAH S SpoIIIAH-like protein
IPCOMLNL_00429 1.2e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IPCOMLNL_00430 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IPCOMLNL_00431 8.1e-67 yqhY S protein conserved in bacteria
IPCOMLNL_00432 1.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IPCOMLNL_00433 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IPCOMLNL_00434 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IPCOMLNL_00435 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IPCOMLNL_00436 3.6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IPCOMLNL_00437 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IPCOMLNL_00438 2.8e-154 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
IPCOMLNL_00439 3.9e-78 argR K Regulates arginine biosynthesis genes
IPCOMLNL_00440 1.2e-305 recN L May be involved in recombinational repair of damaged DNA
IPCOMLNL_00441 8e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
IPCOMLNL_00442 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IPCOMLNL_00443 5.2e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IPCOMLNL_00446 2.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IPCOMLNL_00448 1.2e-112 K Protein of unknown function (DUF1232)
IPCOMLNL_00449 2.2e-100 ytaF P Probably functions as a manganese efflux pump
IPCOMLNL_00450 2.5e-17
IPCOMLNL_00451 5.2e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
IPCOMLNL_00452 1.1e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IPCOMLNL_00453 9.8e-214 mmgA 2.3.1.9 I Belongs to the thiolase family
IPCOMLNL_00454 1.2e-152 hbdA 1.1.1.157 I Dehydrogenase
IPCOMLNL_00455 4.2e-206 mmgC I acyl-CoA dehydrogenase
IPCOMLNL_00456 1.4e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
IPCOMLNL_00457 1.7e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
IPCOMLNL_00458 2.4e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IPCOMLNL_00459 7e-34 yqzF S Protein of unknown function (DUF2627)
IPCOMLNL_00460 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
IPCOMLNL_00461 9.5e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
IPCOMLNL_00462 3.4e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
IPCOMLNL_00463 2e-208 buk 2.7.2.7 C Belongs to the acetokinase family
IPCOMLNL_00464 1.8e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IPCOMLNL_00465 1.9e-162 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IPCOMLNL_00466 1e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IPCOMLNL_00467 1.1e-202 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IPCOMLNL_00468 7.7e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IPCOMLNL_00469 1e-75 yqiW S Belongs to the UPF0403 family
IPCOMLNL_00470 9e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
IPCOMLNL_00471 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
IPCOMLNL_00472 6.5e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IPCOMLNL_00473 5.3e-170 yqjA S Putative aromatic acid exporter C-terminal domain
IPCOMLNL_00474 3.1e-95 yqjB S protein conserved in bacteria
IPCOMLNL_00476 3.6e-73 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
IPCOMLNL_00477 2.7e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IPCOMLNL_00478 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
IPCOMLNL_00479 2.3e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IPCOMLNL_00480 2.4e-25 yqzJ
IPCOMLNL_00481 1.5e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPCOMLNL_00482 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IPCOMLNL_00483 2.5e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IPCOMLNL_00484 2.8e-171 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IPCOMLNL_00485 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IPCOMLNL_00486 5.2e-147 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IPCOMLNL_00487 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IPCOMLNL_00488 1.1e-50 S GlpM protein
IPCOMLNL_00489 1.2e-163 K LysR substrate binding domain
IPCOMLNL_00490 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
IPCOMLNL_00491 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IPCOMLNL_00494 2e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IPCOMLNL_00495 6e-129 IQ reductase
IPCOMLNL_00496 0.0 pksJ Q Polyketide synthase of type I
IPCOMLNL_00497 0.0 pfaA Q Polyketide synthase of type I
IPCOMLNL_00498 0.0 Q Polyketide synthase of type I
IPCOMLNL_00499 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IPCOMLNL_00500 5.8e-219 eryK 1.14.13.154 C Cytochrome P450
IPCOMLNL_00501 2.9e-240 pksG 2.3.3.10 I synthase
IPCOMLNL_00502 5.7e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
IPCOMLNL_00503 3.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPCOMLNL_00504 4.7e-174 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
IPCOMLNL_00505 5.5e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCOMLNL_00506 1e-254 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
IPCOMLNL_00507 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
IPCOMLNL_00508 6.6e-74 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPCOMLNL_00510 1.3e-185 yueF S transporter activity
IPCOMLNL_00512 1.2e-58 S YolD-like protein
IPCOMLNL_00513 7.2e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPCOMLNL_00514 8.7e-89 yqjY K acetyltransferase
IPCOMLNL_00515 4.3e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
IPCOMLNL_00516 5.6e-175 yqkA K GrpB protein
IPCOMLNL_00517 7.7e-61 yqkB S Belongs to the HesB IscA family
IPCOMLNL_00518 3.2e-39 yqkC S Protein of unknown function (DUF2552)
IPCOMLNL_00519 2.8e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
IPCOMLNL_00521 2.8e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
IPCOMLNL_00523 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
IPCOMLNL_00524 9e-220 yqxK 3.6.4.12 L DNA helicase
IPCOMLNL_00525 3e-57 ansR K Transcriptional regulator
IPCOMLNL_00526 8.5e-187 ansA 3.5.1.1 EJ L-asparaginase
IPCOMLNL_00527 3.7e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
IPCOMLNL_00528 2.1e-239 mleN C Na H antiporter
IPCOMLNL_00529 7.7e-244 mleA 1.1.1.38 C malic enzyme
IPCOMLNL_00530 5.7e-22
IPCOMLNL_00531 5e-34 yqkK
IPCOMLNL_00532 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IPCOMLNL_00533 1.9e-80 fur P Belongs to the Fur family
IPCOMLNL_00534 3.7e-37 S Protein of unknown function (DUF4227)
IPCOMLNL_00535 3.7e-165 xerD L recombinase XerD
IPCOMLNL_00536 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IPCOMLNL_00537 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IPCOMLNL_00538 1.1e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
IPCOMLNL_00539 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
IPCOMLNL_00540 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IPCOMLNL_00541 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCOMLNL_00542 3.7e-111 spoVAA S Stage V sporulation protein AA
IPCOMLNL_00543 3.9e-60 spoVAB S Stage V sporulation protein AB
IPCOMLNL_00544 1.3e-78 spoVAC S stage V sporulation protein AC
IPCOMLNL_00545 5e-190 spoVAD I Stage V sporulation protein AD
IPCOMLNL_00546 3.8e-57 spoVAEB S stage V sporulation protein
IPCOMLNL_00547 1.8e-110 spoVAEA S stage V sporulation protein
IPCOMLNL_00548 1.2e-269 spoVAF EG Stage V sporulation protein AF
IPCOMLNL_00549 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IPCOMLNL_00550 5.1e-154 ypuA S Secreted protein
IPCOMLNL_00551 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPCOMLNL_00552 1.8e-81 ccdC1 O Protein of unknown function (DUF1453)
IPCOMLNL_00553 3.8e-99 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IPCOMLNL_00554 6.4e-49 ypuD
IPCOMLNL_00555 1.4e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IPCOMLNL_00556 1.7e-111 ribE 2.5.1.9 H Riboflavin synthase
IPCOMLNL_00557 4.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IPCOMLNL_00558 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IPCOMLNL_00559 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPCOMLNL_00560 4.9e-93 ypuF S Domain of unknown function (DUF309)
IPCOMLNL_00562 8.9e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IPCOMLNL_00563 1.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IPCOMLNL_00564 3.8e-93 ypuI S Protein of unknown function (DUF3907)
IPCOMLNL_00565 6.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
IPCOMLNL_00566 2e-103 spmA S Spore maturation protein
IPCOMLNL_00567 1.3e-88 spmB S Spore maturation protein
IPCOMLNL_00568 8.4e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IPCOMLNL_00569 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IPCOMLNL_00570 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
IPCOMLNL_00571 2.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IPCOMLNL_00572 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCOMLNL_00573 0.0 resE 2.7.13.3 T Histidine kinase
IPCOMLNL_00574 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
IPCOMLNL_00575 2.6e-192 rsiX
IPCOMLNL_00576 9.7e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPCOMLNL_00577 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IPCOMLNL_00578 3.6e-41 fer C Ferredoxin
IPCOMLNL_00579 1.1e-192 ypbB 5.1.3.1 S protein conserved in bacteria
IPCOMLNL_00580 3e-270 recQ 3.6.4.12 L DNA helicase
IPCOMLNL_00581 4e-99 ypbD S metal-dependent membrane protease
IPCOMLNL_00582 9.2e-80 ypbE M Lysin motif
IPCOMLNL_00583 5.7e-85 ypbF S Protein of unknown function (DUF2663)
IPCOMLNL_00584 2.1e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
IPCOMLNL_00585 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IPCOMLNL_00586 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IPCOMLNL_00587 4.5e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
IPCOMLNL_00588 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
IPCOMLNL_00589 7e-161 sleB 3.5.1.28 M Spore cortex-lytic enzyme
IPCOMLNL_00590 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
IPCOMLNL_00591 1.5e-62 ypfA M Flagellar protein YcgR
IPCOMLNL_00592 1.4e-12 S Family of unknown function (DUF5359)
IPCOMLNL_00593 1e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IPCOMLNL_00594 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
IPCOMLNL_00595 6.5e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IPCOMLNL_00596 4.7e-08 S YpzI-like protein
IPCOMLNL_00597 2.5e-104 yphA
IPCOMLNL_00598 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IPCOMLNL_00599 1.9e-189 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IPCOMLNL_00600 8.8e-16 yphE S Protein of unknown function (DUF2768)
IPCOMLNL_00601 6.2e-134 yphF
IPCOMLNL_00602 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IPCOMLNL_00603 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IPCOMLNL_00604 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
IPCOMLNL_00605 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IPCOMLNL_00606 6.9e-136 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IPCOMLNL_00607 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IPCOMLNL_00608 3.7e-196 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IPCOMLNL_00609 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IPCOMLNL_00610 1.1e-140 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
IPCOMLNL_00611 2.1e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IPCOMLNL_00612 1.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IPCOMLNL_00613 4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IPCOMLNL_00614 2.8e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IPCOMLNL_00615 1.2e-159 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IPCOMLNL_00616 2.5e-130 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IPCOMLNL_00617 2.3e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IPCOMLNL_00618 4.9e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IPCOMLNL_00619 7.2e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IPCOMLNL_00620 1.7e-201 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IPCOMLNL_00621 2.7e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IPCOMLNL_00622 3.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IPCOMLNL_00623 7e-234 S COG0457 FOG TPR repeat
IPCOMLNL_00624 2.1e-99 ypiB S Belongs to the UPF0302 family
IPCOMLNL_00625 3.2e-77 ypiF S Protein of unknown function (DUF2487)
IPCOMLNL_00626 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
IPCOMLNL_00627 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
IPCOMLNL_00628 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
IPCOMLNL_00629 2.9e-105 ypjA S membrane
IPCOMLNL_00630 3.6e-140 ypjB S sporulation protein
IPCOMLNL_00631 1.1e-225 oxdC 4.1.1.2 G Oxalate decarboxylase
IPCOMLNL_00632 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
IPCOMLNL_00633 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
IPCOMLNL_00634 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IPCOMLNL_00635 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
IPCOMLNL_00636 5.6e-132 bshB1 S proteins, LmbE homologs
IPCOMLNL_00637 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
IPCOMLNL_00638 1.7e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IPCOMLNL_00639 2.4e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IPCOMLNL_00640 7e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IPCOMLNL_00641 1.1e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IPCOMLNL_00642 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IPCOMLNL_00643 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IPCOMLNL_00644 6.7e-23 ypmA S Protein of unknown function (DUF4264)
IPCOMLNL_00645 9e-81 ypmB S protein conserved in bacteria
IPCOMLNL_00646 3.3e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IPCOMLNL_00647 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
IPCOMLNL_00648 3e-130 dnaD L DNA replication protein DnaD
IPCOMLNL_00649 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IPCOMLNL_00650 1.7e-90 ypoC
IPCOMLNL_00651 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IPCOMLNL_00652 1e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IPCOMLNL_00653 1.3e-187 yppC S Protein of unknown function (DUF2515)
IPCOMLNL_00656 7.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
IPCOMLNL_00658 2.5e-43 yppG S YppG-like protein
IPCOMLNL_00659 1.4e-71 hspX O Belongs to the small heat shock protein (HSP20) family
IPCOMLNL_00660 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
IPCOMLNL_00661 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IPCOMLNL_00662 1.9e-236 yprB L RNase_H superfamily
IPCOMLNL_00664 9.9e-33 cotD S Inner spore coat protein D
IPCOMLNL_00665 2.4e-98 ypsA S Belongs to the UPF0398 family
IPCOMLNL_00666 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IPCOMLNL_00667 4.2e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IPCOMLNL_00668 6.6e-22 S YpzG-like protein
IPCOMLNL_00670 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
IPCOMLNL_00671 1.1e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IPCOMLNL_00672 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IPCOMLNL_00673 1e-232 pbuX F xanthine
IPCOMLNL_00674 3.6e-97 yrdC 3.5.1.19 Q Isochorismatase family
IPCOMLNL_00676 9.8e-49 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
IPCOMLNL_00677 4.5e-106 J Acetyltransferase (GNAT) domain
IPCOMLNL_00678 7e-206 bcsA Q Naringenin-chalcone synthase
IPCOMLNL_00679 1e-87 ypbQ S protein conserved in bacteria
IPCOMLNL_00680 0.0 ypbR S Dynamin family
IPCOMLNL_00681 3.5e-39 ypbS S Protein of unknown function (DUF2533)
IPCOMLNL_00683 2.4e-164 polA 2.7.7.7 L 5'3' exonuclease
IPCOMLNL_00685 1.1e-68 rnhA 3.1.26.4 L Ribonuclease
IPCOMLNL_00686 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IPCOMLNL_00687 2.4e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
IPCOMLNL_00688 9e-19 ypeQ S Zinc-finger
IPCOMLNL_00689 6.1e-36 S Protein of unknown function (DUF2564)
IPCOMLNL_00690 3.3e-12 degR
IPCOMLNL_00691 1e-30 cspD K Cold-shock protein
IPCOMLNL_00692 1.5e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IPCOMLNL_00693 2.5e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IPCOMLNL_00694 3.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IPCOMLNL_00695 1.7e-97 ypgQ S phosphohydrolase
IPCOMLNL_00696 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
IPCOMLNL_00697 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IPCOMLNL_00698 1e-75 yphP S Belongs to the UPF0403 family
IPCOMLNL_00699 2.6e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
IPCOMLNL_00700 2.7e-114 ypjP S YpjP-like protein
IPCOMLNL_00701 1.9e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IPCOMLNL_00702 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IPCOMLNL_00703 1.2e-114 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IPCOMLNL_00704 1.6e-109 hlyIII S protein, Hemolysin III
IPCOMLNL_00705 6.1e-177 pspF K Transcriptional regulator
IPCOMLNL_00706 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IPCOMLNL_00707 2.6e-39 ypmP S Protein of unknown function (DUF2535)
IPCOMLNL_00708 8.7e-107 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IPCOMLNL_00709 4e-136 ypmR E GDSL-like Lipase/Acylhydrolase
IPCOMLNL_00710 1.6e-97 ypmS S protein conserved in bacteria
IPCOMLNL_00711 1.4e-66 ypoP K transcriptional
IPCOMLNL_00712 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPCOMLNL_00713 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IPCOMLNL_00714 4.7e-105 4.2.1.115 GM Polysaccharide biosynthesis protein
IPCOMLNL_00715 6.9e-306 yokA L Recombinase
IPCOMLNL_00718 3.5e-76 yokF 3.1.31.1 L RNA catabolic process
IPCOMLNL_00719 4.5e-19 G SMI1-KNR4 cell-wall
IPCOMLNL_00720 5.6e-56 G SMI1-KNR4 cell-wall
IPCOMLNL_00721 2.5e-250 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IPCOMLNL_00722 1.5e-85 S SMI1-KNR4 cell-wall
IPCOMLNL_00723 7.2e-72 S SMI1-KNR4 cell-wall
IPCOMLNL_00725 4.3e-109 S membrane transporter protein
IPCOMLNL_00726 6.8e-198 2.7.13.3 T Histidine kinase
IPCOMLNL_00727 1.1e-94 nreC T helix_turn_helix, Lux Regulon
IPCOMLNL_00728 7.1e-228 fccB 1.8.5.4 S Pyridine nucleotide-disulphide oxidoreductase
IPCOMLNL_00729 1.5e-274 baeB 3.1.2.6, 3.4.21.102 P Rhodanese Homology Domain
IPCOMLNL_00730 6.6e-33 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPCOMLNL_00732 2.7e-205 S aspartate phosphatase
IPCOMLNL_00735 1.8e-07
IPCOMLNL_00736 4.7e-21 I Acyltransferase family
IPCOMLNL_00737 5.4e-69 yoaW
IPCOMLNL_00740 1.6e-113 3.4.24.40 S amine dehydrogenase activity
IPCOMLNL_00741 2.6e-35 3.4.24.40 S amine dehydrogenase activity
IPCOMLNL_00743 1.6e-194 S aspartate phosphatase
IPCOMLNL_00744 1.4e-75 yoqH M LysM domain
IPCOMLNL_00749 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
IPCOMLNL_00750 9.8e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
IPCOMLNL_00751 4.4e-180 cgeB S Spore maturation protein
IPCOMLNL_00752 1.6e-52 cgeA
IPCOMLNL_00753 1.1e-41 cgeC
IPCOMLNL_00754 1.7e-248 cgeD M maturation of the outermost layer of the spore
IPCOMLNL_00755 2.6e-146 yiiD K acetyltransferase
IPCOMLNL_00757 5.4e-64 yosT L Bacterial transcription activator, effector binding domain
IPCOMLNL_00758 1.2e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPCOMLNL_00759 2.2e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IPCOMLNL_00760 6.7e-122 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IPCOMLNL_00761 5.6e-255 yodQ 3.5.1.16 E Acetylornithine deacetylase
IPCOMLNL_00762 7.3e-158 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
IPCOMLNL_00763 3.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
IPCOMLNL_00764 8.3e-47 yokU S YokU-like protein, putative antitoxin
IPCOMLNL_00765 9.1e-36 yozE S Belongs to the UPF0346 family
IPCOMLNL_00766 6.4e-11 E lactoylglutathione lyase activity
IPCOMLNL_00767 4.9e-125 yodN
IPCOMLNL_00769 6.2e-24 yozD S YozD-like protein
IPCOMLNL_00770 3.1e-100 yodM 3.6.1.27 I Acid phosphatase homologues
IPCOMLNL_00771 3.3e-55 yodL S YodL-like
IPCOMLNL_00773 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IPCOMLNL_00774 8.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IPCOMLNL_00775 4.3e-34 yodI
IPCOMLNL_00776 2.8e-128 yodH Q Methyltransferase
IPCOMLNL_00777 1.4e-254 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IPCOMLNL_00778 3.4e-132 yydK K Transcriptional regulator
IPCOMLNL_00779 1.3e-289 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IPCOMLNL_00780 9.8e-280 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
IPCOMLNL_00781 1e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPCOMLNL_00782 1.8e-19 S Protein of unknown function (DUF3311)
IPCOMLNL_00783 2.9e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
IPCOMLNL_00784 2.3e-110 mhqD S Carboxylesterase
IPCOMLNL_00785 4.5e-106 yodC C nitroreductase
IPCOMLNL_00786 3e-56 yodB K transcriptional
IPCOMLNL_00787 1.4e-70 yoaQ S Evidence 4 Homologs of previously reported genes of
IPCOMLNL_00788 1.6e-67 yodA S tautomerase
IPCOMLNL_00790 2.5e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
IPCOMLNL_00791 5e-162 rarD S -transporter
IPCOMLNL_00792 4.9e-23
IPCOMLNL_00793 9.7e-61 yojF S Protein of unknown function (DUF1806)
IPCOMLNL_00794 2.5e-126 yojG S deacetylase
IPCOMLNL_00795 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IPCOMLNL_00796 7.5e-242 norM V Multidrug efflux pump
IPCOMLNL_00798 4.8e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IPCOMLNL_00799 8.2e-224 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
IPCOMLNL_00800 2.8e-227 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IPCOMLNL_00801 1.9e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IPCOMLNL_00802 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
IPCOMLNL_00803 0.0 yojO P Von Willebrand factor
IPCOMLNL_00804 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IPCOMLNL_00805 7.2e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IPCOMLNL_00806 6.6e-139 S Metallo-beta-lactamase superfamily
IPCOMLNL_00807 1.1e-103 yocS S -transporter
IPCOMLNL_00808 1.9e-234 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IPCOMLNL_00809 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
IPCOMLNL_00810 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
IPCOMLNL_00811 6.4e-287 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
IPCOMLNL_00812 4.7e-31 yozC
IPCOMLNL_00814 2.4e-56 yozO S Bacterial PH domain
IPCOMLNL_00815 8.5e-37 yocN
IPCOMLNL_00816 1.4e-43 yozN
IPCOMLNL_00817 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
IPCOMLNL_00818 1.7e-08
IPCOMLNL_00819 1e-09 yocL
IPCOMLNL_00820 6.8e-60 dksA T general stress protein
IPCOMLNL_00822 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPCOMLNL_00823 0.0 recQ 3.6.4.12 L DNA helicase
IPCOMLNL_00824 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
IPCOMLNL_00826 6.7e-184 yocD 3.4.17.13 V peptidase S66
IPCOMLNL_00827 3.6e-93 yocC
IPCOMLNL_00828 1.1e-139 yocB J Protein required for attachment to host cells
IPCOMLNL_00829 6.9e-90 yozB S membrane
IPCOMLNL_00830 3.9e-119 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IPCOMLNL_00831 1.7e-54 czrA K transcriptional
IPCOMLNL_00832 1.9e-92 yobW
IPCOMLNL_00833 3.8e-136 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
IPCOMLNL_00834 1.8e-93 yobS K Transcriptional regulator
IPCOMLNL_00835 7.3e-132 yobQ K helix_turn_helix, arabinose operon control protein
IPCOMLNL_00836 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
IPCOMLNL_00841 1.6e-08
IPCOMLNL_00848 1.3e-09
IPCOMLNL_00849 7.8e-08
IPCOMLNL_00858 1.7e-76 tspO T membrane
IPCOMLNL_00859 1.7e-131 dksA T COG1734 DnaK suppressor protein
IPCOMLNL_00860 4.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
IPCOMLNL_00861 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IPCOMLNL_00862 7.9e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IPCOMLNL_00863 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IPCOMLNL_00864 5e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IPCOMLNL_00865 1e-212 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IPCOMLNL_00866 1.5e-122 troA P Belongs to the bacterial solute-binding protein 9 family
IPCOMLNL_00867 3.3e-122 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IPCOMLNL_00868 1.4e-157 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IPCOMLNL_00869 4.1e-124 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IPCOMLNL_00870 2.3e-24 S Domain of Unknown Function (DUF1540)
IPCOMLNL_00871 5.8e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IPCOMLNL_00872 2.6e-239 cydA 1.10.3.14 C oxidase, subunit
IPCOMLNL_00873 7.9e-41 rpmE2 J Ribosomal protein L31
IPCOMLNL_00874 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IPCOMLNL_00875 6.2e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IPCOMLNL_00876 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IPCOMLNL_00877 3.6e-76 ytkA S YtkA-like
IPCOMLNL_00879 1.6e-76 dps P Belongs to the Dps family
IPCOMLNL_00880 1.7e-61 ytkC S Bacteriophage holin family
IPCOMLNL_00881 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
IPCOMLNL_00882 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IPCOMLNL_00883 3.2e-144 ytlC P ABC transporter
IPCOMLNL_00884 9.6e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IPCOMLNL_00885 3.3e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IPCOMLNL_00886 1.6e-38 ytmB S Protein of unknown function (DUF2584)
IPCOMLNL_00887 6.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IPCOMLNL_00888 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IPCOMLNL_00889 0.0 asnB 6.3.5.4 E Asparagine synthase
IPCOMLNL_00890 7.4e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
IPCOMLNL_00891 1.9e-57 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IPCOMLNL_00892 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
IPCOMLNL_00893 2.4e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
IPCOMLNL_00894 1.8e-142 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
IPCOMLNL_00896 1.9e-106 ytqB J Putative rRNA methylase
IPCOMLNL_00897 1.4e-189 yhcC S Fe-S oxidoreductase
IPCOMLNL_00898 1.3e-39 ytzC S Protein of unknown function (DUF2524)
IPCOMLNL_00900 8.6e-66 ytrA K GntR family transcriptional regulator
IPCOMLNL_00901 1.9e-161 ytrB P abc transporter atp-binding protein
IPCOMLNL_00902 3.2e-162 S ABC-2 family transporter protein
IPCOMLNL_00903 9.1e-165 P ABC-2 family transporter protein
IPCOMLNL_00904 1.8e-157
IPCOMLNL_00905 2.9e-125 ytrE V ABC transporter, ATP-binding protein
IPCOMLNL_00906 9.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
IPCOMLNL_00907 9.7e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCOMLNL_00908 1.5e-167 T PhoQ Sensor
IPCOMLNL_00909 1.7e-134 bceA V ABC transporter, ATP-binding protein
IPCOMLNL_00910 0.0 bceB V ABC transporter (permease)
IPCOMLNL_00911 3.2e-127 ywaF S Integral membrane protein
IPCOMLNL_00912 1.5e-206 yttB EGP Major facilitator Superfamily
IPCOMLNL_00913 8e-138 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IPCOMLNL_00914 1.2e-52 ytvB S Protein of unknown function (DUF4257)
IPCOMLNL_00915 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IPCOMLNL_00916 1.3e-51 ytwF P Sulfurtransferase
IPCOMLNL_00917 1.7e-84 M Acetyltransferase (GNAT) domain
IPCOMLNL_00918 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
IPCOMLNL_00919 1.4e-142 amyC P ABC transporter (permease)
IPCOMLNL_00920 3.7e-168 amyD G Binding-protein-dependent transport system inner membrane component
IPCOMLNL_00921 1.6e-246 msmE G Bacterial extracellular solute-binding protein
IPCOMLNL_00922 2.8e-185 msmR K Transcriptional regulator
IPCOMLNL_00923 9e-26 yteV S Sporulation protein Cse60
IPCOMLNL_00924 6.7e-27 treR K Periplasmic binding protein LacI transcriptional regulator
IPCOMLNL_00925 2.3e-229 ylbM S Belongs to the UPF0348 family
IPCOMLNL_00926 3.3e-89 yceD S metal-binding, possibly nucleic acid-binding protein
IPCOMLNL_00927 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IPCOMLNL_00928 7.6e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IPCOMLNL_00929 3.1e-89 ylbP K n-acetyltransferase
IPCOMLNL_00930 6.7e-162 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPCOMLNL_00931 1.5e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IPCOMLNL_00932 1.2e-77 mraZ K Belongs to the MraZ family
IPCOMLNL_00933 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IPCOMLNL_00934 1.1e-51 ftsL D Essential cell division protein
IPCOMLNL_00935 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IPCOMLNL_00936 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
IPCOMLNL_00937 7.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IPCOMLNL_00938 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPCOMLNL_00939 2.2e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IPCOMLNL_00940 2.2e-185 spoVE D Belongs to the SEDS family
IPCOMLNL_00941 7.9e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IPCOMLNL_00942 3.7e-168 murB 1.3.1.98 M cell wall formation
IPCOMLNL_00943 3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IPCOMLNL_00944 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IPCOMLNL_00945 1.3e-202 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IPCOMLNL_00946 0.0 bpr O COG1404 Subtilisin-like serine proteases
IPCOMLNL_00947 8.9e-162 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IPCOMLNL_00948 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCOMLNL_00949 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCOMLNL_00950 4.5e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IPCOMLNL_00951 7.2e-255 argE 3.5.1.16 E Acetylornithine deacetylase
IPCOMLNL_00952 2.2e-38 ylmC S sporulation protein
IPCOMLNL_00953 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
IPCOMLNL_00954 6.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IPCOMLNL_00955 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IPCOMLNL_00956 5.2e-41 yggT S membrane
IPCOMLNL_00957 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
IPCOMLNL_00958 8.9e-68 divIVA D Cell division initiation protein
IPCOMLNL_00959 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPCOMLNL_00960 3.8e-63 dksA T COG1734 DnaK suppressor protein
IPCOMLNL_00961 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IPCOMLNL_00962 2.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IPCOMLNL_00963 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IPCOMLNL_00964 2.3e-232 pyrP F Xanthine uracil
IPCOMLNL_00965 4.1e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IPCOMLNL_00966 5e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IPCOMLNL_00967 2.7e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IPCOMLNL_00968 0.0 carB 6.3.5.5 F Belongs to the CarB family
IPCOMLNL_00969 1.9e-141 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IPCOMLNL_00970 6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IPCOMLNL_00971 3.3e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IPCOMLNL_00972 9.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IPCOMLNL_00974 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
IPCOMLNL_00975 1.8e-179 cysP P phosphate transporter
IPCOMLNL_00976 1.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
IPCOMLNL_00977 5.6e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
IPCOMLNL_00978 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IPCOMLNL_00979 6.4e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
IPCOMLNL_00980 1e-79 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
IPCOMLNL_00981 7.5e-77 ctsR K Belongs to the CtsR family
IPCOMLNL_00982 1.5e-100 mcsA 2.7.14.1 S protein with conserved CXXC pairs
IPCOMLNL_00983 5.5e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IPCOMLNL_00984 0.0 clpC O Belongs to the ClpA ClpB family
IPCOMLNL_00985 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IPCOMLNL_00986 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IPCOMLNL_00987 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
IPCOMLNL_00988 5.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IPCOMLNL_00989 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IPCOMLNL_00990 2e-277 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IPCOMLNL_00991 4.7e-117 cysE 2.3.1.30 E Serine acetyltransferase
IPCOMLNL_00992 6.2e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IPCOMLNL_00993 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IPCOMLNL_00994 2.8e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPCOMLNL_00995 4.2e-89 yacP S RNA-binding protein containing a PIN domain
IPCOMLNL_00996 8.9e-116 sigH K Belongs to the sigma-70 factor family
IPCOMLNL_00997 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IPCOMLNL_00998 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
IPCOMLNL_00999 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IPCOMLNL_01000 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IPCOMLNL_01001 2.5e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IPCOMLNL_01002 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IPCOMLNL_01003 1.2e-106 rsmC 2.1.1.172 J Methyltransferase
IPCOMLNL_01004 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPCOMLNL_01005 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPCOMLNL_01006 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
IPCOMLNL_01007 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IPCOMLNL_01008 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IPCOMLNL_01009 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IPCOMLNL_01010 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPCOMLNL_01011 1.6e-185 ybaC 3.4.11.5 S Alpha/beta hydrolase family
IPCOMLNL_01012 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IPCOMLNL_01013 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IPCOMLNL_01014 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
IPCOMLNL_01015 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IPCOMLNL_01016 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IPCOMLNL_01017 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IPCOMLNL_01018 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IPCOMLNL_01019 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IPCOMLNL_01020 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IPCOMLNL_01021 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
IPCOMLNL_01022 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IPCOMLNL_01023 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IPCOMLNL_01024 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IPCOMLNL_01025 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IPCOMLNL_01026 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPCOMLNL_01027 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IPCOMLNL_01028 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IPCOMLNL_01029 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IPCOMLNL_01030 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IPCOMLNL_01031 1.9e-23 rpmD J Ribosomal protein L30
IPCOMLNL_01032 1.1e-72 rplO J binds to the 23S rRNA
IPCOMLNL_01033 6e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IPCOMLNL_01034 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IPCOMLNL_01035 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
IPCOMLNL_01036 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IPCOMLNL_01037 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IPCOMLNL_01038 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IPCOMLNL_01039 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IPCOMLNL_01040 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPCOMLNL_01041 4.7e-58 rplQ J Ribosomal protein L17
IPCOMLNL_01042 8.7e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPCOMLNL_01043 3.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPCOMLNL_01044 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPCOMLNL_01045 1.1e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IPCOMLNL_01046 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IPCOMLNL_01047 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
IPCOMLNL_01048 5.3e-144 ybaJ Q Methyltransferase domain
IPCOMLNL_01049 6.1e-82 yizA S Damage-inducible protein DinB
IPCOMLNL_01050 6.5e-78 ybaK S Protein of unknown function (DUF2521)
IPCOMLNL_01051 7.9e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IPCOMLNL_01052 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IPCOMLNL_01053 1.7e-75 gerD
IPCOMLNL_01054 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
IPCOMLNL_01055 2.5e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
IPCOMLNL_01057 9.6e-10 M Rhs element Vgr
IPCOMLNL_01058 2.2e-30 csfB S Inhibitor of sigma-G Gin
IPCOMLNL_01059 1e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IPCOMLNL_01060 6e-189 yaaN P Belongs to the TelA family
IPCOMLNL_01061 7.5e-269 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
IPCOMLNL_01062 1.5e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IPCOMLNL_01063 7.5e-55 yaaQ S protein conserved in bacteria
IPCOMLNL_01064 1.7e-70 yaaR S protein conserved in bacteria
IPCOMLNL_01065 1.3e-182 holB 2.7.7.7 L DNA polymerase III
IPCOMLNL_01066 8.8e-145 yaaT S stage 0 sporulation protein
IPCOMLNL_01067 7.7e-37 yabA L Involved in initiation control of chromosome replication
IPCOMLNL_01068 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
IPCOMLNL_01069 5.2e-47 yazA L endonuclease containing a URI domain
IPCOMLNL_01070 1.6e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IPCOMLNL_01071 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
IPCOMLNL_01072 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPCOMLNL_01073 1.1e-141 tatD L hydrolase, TatD
IPCOMLNL_01074 1.8e-232 rpfB GH23 T protein conserved in bacteria
IPCOMLNL_01075 3.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IPCOMLNL_01076 1.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IPCOMLNL_01077 8.4e-146 yabG S peptidase
IPCOMLNL_01078 7.8e-39 veg S protein conserved in bacteria
IPCOMLNL_01079 2.9e-27 sspF S DNA topological change
IPCOMLNL_01080 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IPCOMLNL_01081 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IPCOMLNL_01082 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
IPCOMLNL_01083 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IPCOMLNL_01084 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IPCOMLNL_01085 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IPCOMLNL_01086 1.7e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IPCOMLNL_01087 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IPCOMLNL_01088 3.7e-40 yabK S Peptide ABC transporter permease
IPCOMLNL_01089 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IPCOMLNL_01090 6.2e-91 spoVT K stage V sporulation protein
IPCOMLNL_01091 2.4e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPCOMLNL_01092 1e-276 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IPCOMLNL_01093 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IPCOMLNL_01094 1.9e-49 yabP S Sporulation protein YabP
IPCOMLNL_01095 1.4e-102 yabQ S spore cortex biosynthesis protein
IPCOMLNL_01096 2.3e-52 divIC D Septum formation initiator
IPCOMLNL_01097 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
IPCOMLNL_01100 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
IPCOMLNL_01101 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
IPCOMLNL_01102 6.2e-185 KLT serine threonine protein kinase
IPCOMLNL_01103 7.2e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IPCOMLNL_01104 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IPCOMLNL_01105 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPCOMLNL_01106 4.8e-145 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IPCOMLNL_01107 5.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IPCOMLNL_01108 6.5e-154 yacD 5.2.1.8 O peptidyl-prolyl isomerase
IPCOMLNL_01109 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IPCOMLNL_01110 2e-269 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IPCOMLNL_01111 2.3e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
IPCOMLNL_01112 2.1e-160 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
IPCOMLNL_01113 5.2e-156 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IPCOMLNL_01114 7e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IPCOMLNL_01115 2.2e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IPCOMLNL_01116 4.5e-29 yazB K transcriptional
IPCOMLNL_01117 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPCOMLNL_01118 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IPCOMLNL_01119 1.1e-281 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
IPCOMLNL_01120 3.3e-236 ytfP S HI0933-like protein
IPCOMLNL_01121 7.7e-294 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPCOMLNL_01122 1.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IPCOMLNL_01123 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
IPCOMLNL_01124 3.7e-128 ythP V ABC transporter
IPCOMLNL_01125 7.1e-217 ythQ U Bacterial ABC transporter protein EcsB
IPCOMLNL_01126 5.3e-229 pbuO S permease
IPCOMLNL_01127 2.1e-268 pepV 3.5.1.18 E Dipeptidase
IPCOMLNL_01128 3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IPCOMLNL_01129 1.8e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IPCOMLNL_01130 5.2e-170 ytlQ
IPCOMLNL_01131 1.8e-178 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IPCOMLNL_01132 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
IPCOMLNL_01133 3.5e-45 ytzH S YtzH-like protein
IPCOMLNL_01134 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IPCOMLNL_01135 5.1e-164 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
IPCOMLNL_01136 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
IPCOMLNL_01137 1.7e-51 ytzB S small secreted protein
IPCOMLNL_01138 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IPCOMLNL_01139 1.7e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
IPCOMLNL_01140 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IPCOMLNL_01141 3.7e-148 ytpQ S Belongs to the UPF0354 family
IPCOMLNL_01142 7e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IPCOMLNL_01143 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
IPCOMLNL_01144 1.1e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IPCOMLNL_01145 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IPCOMLNL_01146 1.7e-16 ytxH S COG4980 Gas vesicle protein
IPCOMLNL_01147 5.9e-44 ytxJ O Protein of unknown function (DUF2847)
IPCOMLNL_01148 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IPCOMLNL_01149 6.4e-182 ccpA K catabolite control protein A
IPCOMLNL_01150 5.1e-145 motA N flagellar motor
IPCOMLNL_01151 3.7e-120 motS N Flagellar motor protein
IPCOMLNL_01152 5.6e-230 acuC BQ histone deacetylase
IPCOMLNL_01153 2.7e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
IPCOMLNL_01154 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IPCOMLNL_01155 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IPCOMLNL_01156 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPCOMLNL_01157 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
IPCOMLNL_01158 7.6e-124 azlC E AzlC protein
IPCOMLNL_01159 4.4e-149 K Transcriptional regulator
IPCOMLNL_01160 1.1e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPCOMLNL_01161 3.3e-138 E GDSL-like Lipase/Acylhydrolase family
IPCOMLNL_01163 1.5e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
IPCOMLNL_01164 1.5e-188 yoxA 5.1.3.3 G Aldose 1-epimerase
IPCOMLNL_01165 7.9e-247 yoeA V MATE efflux family protein
IPCOMLNL_01166 3.8e-96 yoeB S IseA DL-endopeptidase inhibitor
IPCOMLNL_01168 3.5e-97 L Integrase
IPCOMLNL_01169 1.8e-34 yoeD G Helix-turn-helix domain
IPCOMLNL_01170 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IPCOMLNL_01171 1.2e-200 ybcL EGP Major facilitator Superfamily
IPCOMLNL_01172 6.7e-50 ybzH K Helix-turn-helix domain
IPCOMLNL_01173 3.2e-14 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPCOMLNL_01174 1.7e-154 gltR1 K Transcriptional regulator
IPCOMLNL_01175 9.3e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IPCOMLNL_01176 3.2e-50 1.16.3.1 S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
IPCOMLNL_01177 1.7e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IPCOMLNL_01178 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
IPCOMLNL_01179 1.6e-152 gltC K Transcriptional regulator
IPCOMLNL_01180 8.1e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IPCOMLNL_01181 3.7e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPCOMLNL_01182 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IPCOMLNL_01183 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCOMLNL_01184 5.7e-41 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IPCOMLNL_01185 1.4e-136 yoxB
IPCOMLNL_01186 1.9e-204 yoaB EGP Major facilitator Superfamily
IPCOMLNL_01187 1.8e-273 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
IPCOMLNL_01188 2.1e-193 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPCOMLNL_01189 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IPCOMLNL_01190 6.3e-26 yoaF
IPCOMLNL_01192 4.3e-98 hpr K helix_turn_helix multiple antibiotic resistance protein
IPCOMLNL_01193 1.1e-43
IPCOMLNL_01194 1.8e-86 S SMI1-KNR4 cell-wall
IPCOMLNL_01195 1e-161 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IPCOMLNL_01196 1.6e-34 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IPCOMLNL_01197 0.0 Q Polyketide synthase of type I
IPCOMLNL_01198 0.0 1.1.1.320 Q Polyketide synthase of type I
IPCOMLNL_01199 0.0 pksJ Q Polyketide synthase of type I
IPCOMLNL_01200 7.5e-183 yaaC S YaaC-like Protein
IPCOMLNL_01201 1.2e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IPCOMLNL_01202 1.2e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IPCOMLNL_01203 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IPCOMLNL_01204 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IPCOMLNL_01205 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPCOMLNL_01206 1.7e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IPCOMLNL_01207 1.3e-09
IPCOMLNL_01208 5.4e-121 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
IPCOMLNL_01209 5.5e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
IPCOMLNL_01210 2.2e-211 yaaH M Glycoside Hydrolase Family
IPCOMLNL_01211 3.7e-99 yaaI Q COG1335 Amidases related to nicotinamidase
IPCOMLNL_01212 2.3e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IPCOMLNL_01213 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPCOMLNL_01214 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IPCOMLNL_01215 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IPCOMLNL_01216 3.6e-32 yaaL S Protein of unknown function (DUF2508)
IPCOMLNL_01217 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
IPCOMLNL_01218 1.2e-23 D Protein of unknown function (DUF3375)
IPCOMLNL_01219 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_01220 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_01221 4.2e-21 T Histidine kinase
IPCOMLNL_01222 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_01223 3.1e-83 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_01224 1.1e-77 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_01225 2.5e-71 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_01226 1.3e-35 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_01227 2.1e-188 ylbL T Belongs to the peptidase S16 family
IPCOMLNL_01228 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
IPCOMLNL_01229 5.7e-217 ylbJ S Sporulation integral membrane protein YlbJ
IPCOMLNL_01230 7.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IPCOMLNL_01231 8.5e-90 rsmD 2.1.1.171 L Methyltransferase
IPCOMLNL_01233 7.2e-43 ylbG S UPF0298 protein
IPCOMLNL_01234 1.2e-71 ylbF S Belongs to the UPF0342 family
IPCOMLNL_01235 8.8e-37 ylbE S YlbE-like protein
IPCOMLNL_01236 6.5e-56 ylbD S Putative coat protein
IPCOMLNL_01237 5.1e-198 ylbC S protein with SCP PR1 domains
IPCOMLNL_01238 6.3e-73 ylbB T COG0517 FOG CBS domain
IPCOMLNL_01239 8.5e-60 ylbA S YugN-like family
IPCOMLNL_01240 4.8e-165 ctaG S cytochrome c oxidase
IPCOMLNL_01241 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IPCOMLNL_01242 5.3e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IPCOMLNL_01243 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IPCOMLNL_01244 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IPCOMLNL_01245 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IPCOMLNL_01246 1.9e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IPCOMLNL_01247 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IPCOMLNL_01248 9.4e-212 ftsW D Belongs to the SEDS family
IPCOMLNL_01249 8.7e-44 ylaN S Belongs to the UPF0358 family
IPCOMLNL_01250 2.1e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
IPCOMLNL_01251 2.2e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IPCOMLNL_01252 9.2e-245 phoH T ATPase related to phosphate starvation-inducible protein PhoH
IPCOMLNL_01253 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IPCOMLNL_01254 1e-33 ylaI S protein conserved in bacteria
IPCOMLNL_01255 6.6e-48 ylaH S YlaH-like protein
IPCOMLNL_01256 0.0 typA T GTP-binding protein TypA
IPCOMLNL_01257 6.7e-24 S Family of unknown function (DUF5325)
IPCOMLNL_01258 5.7e-40 ylaE
IPCOMLNL_01259 1.3e-13 sigC S Putative zinc-finger
IPCOMLNL_01260 1.9e-294 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
IPCOMLNL_01261 2e-82 ykzC S Acetyltransferase (GNAT) family
IPCOMLNL_01262 1.1e-149 suhB 3.1.3.25 G Inositol monophosphatase
IPCOMLNL_01263 6.3e-24 ykzI
IPCOMLNL_01264 4.9e-119 yktB S Belongs to the UPF0637 family
IPCOMLNL_01265 1.6e-42 yktA S Belongs to the UPF0223 family
IPCOMLNL_01266 1.7e-276 speA 4.1.1.19 E Arginine
IPCOMLNL_01267 9.3e-136 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
IPCOMLNL_01268 1e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
IPCOMLNL_01269 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IPCOMLNL_01270 2.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IPCOMLNL_01271 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IPCOMLNL_01272 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IPCOMLNL_01273 1.3e-209 V Beta-lactamase
IPCOMLNL_01274 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
IPCOMLNL_01275 0.0 Q Polyketide synthase of type I
IPCOMLNL_01276 0.0 Q Polyketide synthase of type I
IPCOMLNL_01277 0.0 Q Polyketide synthase of type I
IPCOMLNL_01278 0.0 Q Polyketide synthase of type I
IPCOMLNL_01279 0.0 Q polyketide synthase
IPCOMLNL_01280 0.0 Q Polyketide synthase of type I
IPCOMLNL_01281 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IPCOMLNL_01282 2.9e-103 recN L Putative cell-wall binding lipoprotein
IPCOMLNL_01284 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IPCOMLNL_01285 9.7e-146 ykrA S hydrolases of the HAD superfamily
IPCOMLNL_01286 8.2e-31 ykzG S Belongs to the UPF0356 family
IPCOMLNL_01287 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPCOMLNL_01288 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IPCOMLNL_01289 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
IPCOMLNL_01290 3.8e-148 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
IPCOMLNL_01291 6.3e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
IPCOMLNL_01292 1.8e-44 abrB K of stationary sporulation gene expression
IPCOMLNL_01293 2.6e-183 mreB D Rod-share determining protein MreBH
IPCOMLNL_01294 5.5e-12 S Uncharacterized protein YkpC
IPCOMLNL_01295 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IPCOMLNL_01296 1.8e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPCOMLNL_01297 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IPCOMLNL_01298 9.8e-37 ykoA
IPCOMLNL_01299 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IPCOMLNL_01300 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IPCOMLNL_01301 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
IPCOMLNL_01302 4.6e-132 fruR K Transcriptional regulator
IPCOMLNL_01303 3.9e-210 yknZ V ABC transporter (permease)
IPCOMLNL_01304 6.1e-123 macB V ABC transporter, ATP-binding protein
IPCOMLNL_01305 1.5e-171 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IPCOMLNL_01306 1.7e-104 yknW S Yip1 domain
IPCOMLNL_01307 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IPCOMLNL_01308 3.5e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
IPCOMLNL_01309 3.8e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
IPCOMLNL_01310 2.9e-243 moeA 2.10.1.1 H molybdopterin
IPCOMLNL_01311 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IPCOMLNL_01312 8.2e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IPCOMLNL_01313 2.5e-162 yknT
IPCOMLNL_01314 4.5e-98 rok K Repressor of ComK
IPCOMLNL_01315 7.9e-79 ykuV CO thiol-disulfide
IPCOMLNL_01316 1.9e-139 ykuT M Mechanosensitive ion channel
IPCOMLNL_01317 4.8e-38 ykuS S Belongs to the UPF0180 family
IPCOMLNL_01318 1.5e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IPCOMLNL_01319 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IPCOMLNL_01320 9.3e-80 fld C Flavodoxin
IPCOMLNL_01321 1.8e-172 ykuO
IPCOMLNL_01322 6.1e-90 fld C Flavodoxin
IPCOMLNL_01323 4.6e-168 ccpC K Transcriptional regulator
IPCOMLNL_01324 1e-75 ykuL S CBS domain
IPCOMLNL_01325 2.1e-25 ykzF S Antirepressor AbbA
IPCOMLNL_01326 7.6e-94 ykuK S Ribonuclease H-like
IPCOMLNL_01327 3.9e-37 ykuJ S protein conserved in bacteria
IPCOMLNL_01328 1.7e-232 ykuI T Diguanylate phosphodiesterase
IPCOMLNL_01330 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCOMLNL_01331 2.6e-155 ykuE S Metallophosphoesterase
IPCOMLNL_01332 1.7e-87 ykuD S protein conserved in bacteria
IPCOMLNL_01333 7.3e-239 ykuC EGP Major facilitator Superfamily
IPCOMLNL_01334 1.4e-83 ykyB S YkyB-like protein
IPCOMLNL_01335 1e-165 cheV 2.7.13.3 T Chemotaxis protein CheV
IPCOMLNL_01336 8e-10
IPCOMLNL_01337 3.9e-215 patA 2.6.1.1 E Aminotransferase
IPCOMLNL_01338 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
IPCOMLNL_01339 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
IPCOMLNL_01340 9.8e-114 ykwD J protein with SCP PR1 domains
IPCOMLNL_01341 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IPCOMLNL_01342 6.2e-264 mcpC NT chemotaxis protein
IPCOMLNL_01343 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
IPCOMLNL_01344 6.1e-38 splA S Transcriptional regulator
IPCOMLNL_01345 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPCOMLNL_01346 2.1e-39 ptsH G phosphocarrier protein HPr
IPCOMLNL_01347 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IPCOMLNL_01348 5.1e-156 glcT K antiterminator
IPCOMLNL_01349 1.9e-175 ykvZ 5.1.1.1 K Transcriptional regulator
IPCOMLNL_01351 1.1e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IPCOMLNL_01352 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IPCOMLNL_01353 2.9e-87 stoA CO thiol-disulfide
IPCOMLNL_01354 1.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPCOMLNL_01355 2.4e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
IPCOMLNL_01356 7.9e-28
IPCOMLNL_01357 7.8e-25 ykvS S protein conserved in bacteria
IPCOMLNL_01358 1e-44 ykvR S Protein of unknown function (DUF3219)
IPCOMLNL_01359 3.1e-256 S AIPR protein
IPCOMLNL_01361 2.9e-30 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IPCOMLNL_01362 9.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
IPCOMLNL_01363 2e-61 ykvN K Transcriptional regulator
IPCOMLNL_01364 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IPCOMLNL_01365 2.1e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IPCOMLNL_01366 1.3e-78 queD 4.1.2.50, 4.2.3.12 H synthase
IPCOMLNL_01367 2.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IPCOMLNL_01368 2.1e-186
IPCOMLNL_01369 7.8e-183 ykvI S membrane
IPCOMLNL_01370 0.0 clpE O Belongs to the ClpA ClpB family
IPCOMLNL_01371 1.1e-136 motA N flagellar motor
IPCOMLNL_01372 4.6e-127 motB N Flagellar motor protein
IPCOMLNL_01373 5.5e-77 ykvE K transcriptional
IPCOMLNL_01374 2.1e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
IPCOMLNL_01375 3.4e-10 S Spo0E like sporulation regulatory protein
IPCOMLNL_01376 6.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IPCOMLNL_01377 4.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IPCOMLNL_01378 1e-133 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IPCOMLNL_01379 1.8e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IPCOMLNL_01380 1.9e-228 mtnE 2.6.1.83 E Aminotransferase
IPCOMLNL_01381 1.9e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IPCOMLNL_01382 1e-226 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IPCOMLNL_01383 1.8e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IPCOMLNL_01385 1e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IPCOMLNL_01386 0.0 kinE 2.7.13.3 T Histidine kinase
IPCOMLNL_01387 1e-187 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
IPCOMLNL_01388 3e-23 ykzE
IPCOMLNL_01389 3.3e-33 ydfR S Protein of unknown function (DUF421)
IPCOMLNL_01390 1.7e-71 ydfR S Protein of unknown function (DUF421)
IPCOMLNL_01391 1.3e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
IPCOMLNL_01392 4.1e-156 htpX O Belongs to the peptidase M48B family
IPCOMLNL_01393 2.7e-126 ykrK S Domain of unknown function (DUF1836)
IPCOMLNL_01394 2.5e-26 sspD S small acid-soluble spore protein
IPCOMLNL_01395 3.1e-119 rsgI S Anti-sigma factor N-terminus
IPCOMLNL_01396 1.3e-126 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCOMLNL_01397 2.1e-135 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IPCOMLNL_01398 4.1e-101 ykoX S membrane-associated protein
IPCOMLNL_01399 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IPCOMLNL_01400 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
IPCOMLNL_01401 2.2e-99 ykoP G polysaccharide deacetylase
IPCOMLNL_01402 1.1e-80 ykoM K transcriptional
IPCOMLNL_01403 1.2e-25 ykoL
IPCOMLNL_01404 1.9e-16
IPCOMLNL_01405 1.6e-52 tnrA K transcriptional
IPCOMLNL_01406 5e-238 mgtE P Acts as a magnesium transporter
IPCOMLNL_01408 3e-245 ydhD M Glycosyl hydrolase
IPCOMLNL_01409 8.4e-97 ykoE S ABC-type cobalt transport system, permease component
IPCOMLNL_01410 3.4e-305 P ABC transporter, ATP-binding protein
IPCOMLNL_01411 1.2e-132 ykoC P Cobalt transport protein
IPCOMLNL_01412 1.8e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IPCOMLNL_01413 1.1e-175 isp O Belongs to the peptidase S8 family
IPCOMLNL_01414 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IPCOMLNL_01415 2.5e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IPCOMLNL_01416 5.5e-217 hcaT 1.5.1.2 EGP Major facilitator Superfamily
IPCOMLNL_01417 5.2e-124 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
IPCOMLNL_01418 4.9e-215 M Glycosyl transferase family 2
IPCOMLNL_01420 1.1e-56 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IPCOMLNL_01421 9.3e-71 ohrB O Organic hydroperoxide resistance protein
IPCOMLNL_01422 1.5e-86 ohrR K COG1846 Transcriptional regulators
IPCOMLNL_01423 1.3e-70 ohrA O Organic hydroperoxide resistance protein
IPCOMLNL_01424 1.8e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IPCOMLNL_01425 7.3e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IPCOMLNL_01426 3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IPCOMLNL_01427 3.4e-49 ykkD P Multidrug resistance protein
IPCOMLNL_01428 2.7e-52 ykkC P Multidrug resistance protein
IPCOMLNL_01429 1.5e-100 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IPCOMLNL_01430 1.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
IPCOMLNL_01431 1.2e-157 ykgA E Amidinotransferase
IPCOMLNL_01432 5.1e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
IPCOMLNL_01433 9.6e-183 ykfD E Belongs to the ABC transporter superfamily
IPCOMLNL_01434 5e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IPCOMLNL_01435 2.6e-197 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IPCOMLNL_01436 1.6e-174 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
IPCOMLNL_01437 0.0 dppE E ABC transporter substrate-binding protein
IPCOMLNL_01438 2e-191 dppD P Belongs to the ABC transporter superfamily
IPCOMLNL_01439 8.5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCOMLNL_01440 1.4e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCOMLNL_01441 6.5e-156 dppA E D-aminopeptidase
IPCOMLNL_01443 3.4e-283 yubD P Major Facilitator Superfamily
IPCOMLNL_01444 1.2e-202 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPCOMLNL_01446 4.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IPCOMLNL_01447 3.5e-302 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPCOMLNL_01448 4.8e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
IPCOMLNL_01449 3.8e-243 steT E amino acid
IPCOMLNL_01450 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
IPCOMLNL_01451 5.8e-175 pit P phosphate transporter
IPCOMLNL_01452 1.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
IPCOMLNL_01453 8.7e-23 spoIISB S Stage II sporulation protein SB
IPCOMLNL_01454 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IPCOMLNL_01455 1.3e-38 xhlB S SPP1 phage holin
IPCOMLNL_01456 8.7e-38 xhlA S Haemolysin XhlA
IPCOMLNL_01457 4.8e-137 xepA
IPCOMLNL_01458 6.5e-30 xkdX
IPCOMLNL_01460 6.1e-187
IPCOMLNL_01461 1.2e-26
IPCOMLNL_01462 1.4e-85 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
IPCOMLNL_01463 3.3e-165 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IPCOMLNL_01464 7.2e-58 xkdS S Protein of unknown function (DUF2634)
IPCOMLNL_01465 1.2e-31 xkdR S Protein of unknown function (DUF2577)
IPCOMLNL_01466 7.2e-162 xkdQ 3.2.1.96 G NLP P60 protein
IPCOMLNL_01467 1.5e-110 xkdP S Lysin motif
IPCOMLNL_01468 8.2e-190 xkdO L Transglycosylase SLT domain
IPCOMLNL_01469 3.4e-19
IPCOMLNL_01470 4.9e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
IPCOMLNL_01471 2e-74 xkdM S Phage tail tube protein
IPCOMLNL_01472 1e-225 xkdK S Phage tail sheath C-terminal domain
IPCOMLNL_01473 3.1e-14
IPCOMLNL_01474 4.9e-57 xkdJ
IPCOMLNL_01475 2.4e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
IPCOMLNL_01476 6e-42 yqbH S Domain of unknown function (DUF3599)
IPCOMLNL_01477 2e-46 yqbG S Protein of unknown function (DUF3199)
IPCOMLNL_01478 1e-157 xkdG S Phage capsid family
IPCOMLNL_01479 2.8e-90 xkdF 2.1.1.72 L Putative phage serine protease XkdF
IPCOMLNL_01480 5.1e-241 yqbA S portal protein
IPCOMLNL_01481 6.1e-209 xtmB S phage terminase, large subunit
IPCOMLNL_01482 6.1e-111 xtmA L phage terminase small subunit
IPCOMLNL_01483 2.8e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IPCOMLNL_01484 2.7e-10 yqaO S Phage-like element PBSX protein XtrA
IPCOMLNL_01487 2.2e-119 xkdC L Bacterial dnaA protein
IPCOMLNL_01488 2.6e-112 xkdB K sequence-specific DNA binding
IPCOMLNL_01490 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
IPCOMLNL_01491 3.8e-110 xkdA E IrrE N-terminal-like domain
IPCOMLNL_01492 1.1e-147 ydbD P Catalase
IPCOMLNL_01493 9.7e-109 yjqB S phage-related replication protein
IPCOMLNL_01494 1e-60 yjqA S Bacterial PH domain
IPCOMLNL_01495 3.2e-167 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IPCOMLNL_01497 4.9e-215 S response regulator aspartate phosphatase
IPCOMLNL_01498 3.1e-78 yjoA S DinB family
IPCOMLNL_01499 3.9e-131 MA20_18170 S membrane transporter protein
IPCOMLNL_01500 1.2e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
IPCOMLNL_01501 8.7e-281 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
IPCOMLNL_01502 3.4e-183 exuR K transcriptional
IPCOMLNL_01503 3.9e-254 yjmB G symporter YjmB
IPCOMLNL_01504 3.3e-277 uxaC 5.3.1.12 G glucuronate isomerase
IPCOMLNL_01505 1.3e-218 yjlD 1.6.99.3 C NADH dehydrogenase
IPCOMLNL_01506 7e-66 yjlC S Protein of unknown function (DUF1641)
IPCOMLNL_01507 1.5e-91 yjlB S Cupin domain
IPCOMLNL_01508 3.9e-176 yjlA EG Putative multidrug resistance efflux transporter
IPCOMLNL_01509 6.4e-131 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
IPCOMLNL_01510 1.8e-120 ybbM S transport system, permease component
IPCOMLNL_01511 2.1e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IPCOMLNL_01512 2e-28
IPCOMLNL_01513 9.8e-222 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IPCOMLNL_01514 1.1e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
IPCOMLNL_01515 4.3e-92 yjgD S Protein of unknown function (DUF1641)
IPCOMLNL_01516 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
IPCOMLNL_01517 7.8e-100 yjgB S Domain of unknown function (DUF4309)
IPCOMLNL_01518 4.2e-68 T PhoQ Sensor
IPCOMLNL_01519 7.5e-22 yjfB S Putative motility protein
IPCOMLNL_01521 8.1e-106 yhiD S MgtC SapB transporter
IPCOMLNL_01522 3.8e-51 K helix_turn_helix multiple antibiotic resistance protein
IPCOMLNL_01523 2.6e-34
IPCOMLNL_01524 1.3e-125 5.4.2.6 S Haloacid dehalogenase-like hydrolase
IPCOMLNL_01525 5.7e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
IPCOMLNL_01526 5.3e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
IPCOMLNL_01527 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
IPCOMLNL_01528 4.7e-311 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPCOMLNL_01529 6.7e-215 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IPCOMLNL_01530 8.5e-187 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IPCOMLNL_01531 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IPCOMLNL_01532 9.5e-219 ganA 3.2.1.89 G arabinogalactan
IPCOMLNL_01533 1.4e-81 napB K helix_turn_helix multiple antibiotic resistance protein
IPCOMLNL_01534 4.1e-251 yfjF EGP Belongs to the major facilitator superfamily
IPCOMLNL_01535 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
IPCOMLNL_01536 1.2e-147 bla 3.5.2.6 V beta-lactamase
IPCOMLNL_01537 2.4e-10 yqaS L DNA packaging
IPCOMLNL_01538 5.5e-10 yqaS L DNA packaging
IPCOMLNL_01541 4.2e-16
IPCOMLNL_01542 7.3e-19
IPCOMLNL_01545 3.7e-10 K Transcriptional regulator
IPCOMLNL_01546 1.8e-08
IPCOMLNL_01549 2.3e-73 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
IPCOMLNL_01550 2.8e-44 FG Scavenger mRNA decapping enzyme C-term binding
IPCOMLNL_01551 2e-84 yqjL S Alpha beta hydrolase
IPCOMLNL_01552 2.6e-202 M nucleic acid phosphodiester bond hydrolysis
IPCOMLNL_01553 3.8e-29
IPCOMLNL_01554 5.8e-22
IPCOMLNL_01555 1.9e-21
IPCOMLNL_01562 3e-10 K Cro/C1-type HTH DNA-binding domain
IPCOMLNL_01565 1.2e-14 K Helix-turn-helix domain
IPCOMLNL_01567 4.5e-46 M D-alanyl-D-alanine carboxypeptidase
IPCOMLNL_01568 8.7e-45 S Bacteriophage holin family
IPCOMLNL_01570 1.4e-14
IPCOMLNL_01571 5.6e-67 S Domain of unknown function (DUF2479)
IPCOMLNL_01572 1.6e-264 M Pectate lyase superfamily protein
IPCOMLNL_01573 3.2e-102 mur1 NU Prophage endopeptidase tail
IPCOMLNL_01574 1.5e-46 S Phage tail protein
IPCOMLNL_01575 4.4e-139 D Phage-related minor tail protein
IPCOMLNL_01577 4.2e-51 S phage major tail protein, phi13 family
IPCOMLNL_01578 2.4e-28
IPCOMLNL_01579 1.1e-20 S Bacteriophage HK97-gp10, putative tail-component
IPCOMLNL_01581 2.3e-12 S Phage gp6-like head-tail connector protein
IPCOMLNL_01582 1.4e-88 S Phage capsid family
IPCOMLNL_01583 2.5e-48 S Caudovirus prohead serine protease
IPCOMLNL_01584 2.1e-110 S Phage portal protein
IPCOMLNL_01585 1.6e-172 S Phage Terminase
IPCOMLNL_01586 1e-16
IPCOMLNL_01591 3.2e-53 K BRO family, N-terminal domain
IPCOMLNL_01595 7.5e-63
IPCOMLNL_01596 3.8e-41 S DNA binding
IPCOMLNL_01599 4.2e-81 L Belongs to the 'phage' integrase family
IPCOMLNL_01601 2.4e-212 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IPCOMLNL_01602 9.6e-211 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IPCOMLNL_01603 8e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
IPCOMLNL_01604 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
IPCOMLNL_01605 1.9e-74 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPCOMLNL_01607 9.4e-36 K SpoVT / AbrB like domain
IPCOMLNL_01608 1.2e-132 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
IPCOMLNL_01609 1.2e-124 S ABC-2 type transporter
IPCOMLNL_01610 2.5e-141 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
IPCOMLNL_01611 6.7e-35
IPCOMLNL_01612 0.0 yjcD 3.6.4.12 L DNA helicase
IPCOMLNL_01613 3.8e-38 spoVIF S Stage VI sporulation protein F
IPCOMLNL_01617 7.3e-56 yjcA S Protein of unknown function (DUF1360)
IPCOMLNL_01618 1.4e-39 cotV S Spore Coat Protein X and V domain
IPCOMLNL_01619 2.3e-21 cotW
IPCOMLNL_01620 5.1e-71 cotX S Spore Coat Protein X and V domain
IPCOMLNL_01621 1.7e-92 cotY S Spore coat protein Z
IPCOMLNL_01622 6.7e-83 cotZ S Spore coat protein
IPCOMLNL_01623 1.9e-83 yjbX S Spore coat protein
IPCOMLNL_01624 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IPCOMLNL_01625 5.4e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IPCOMLNL_01626 1.8e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IPCOMLNL_01627 3.4e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IPCOMLNL_01628 1.4e-30 thiS H Thiamine biosynthesis
IPCOMLNL_01629 4.5e-213 thiO 1.4.3.19 E Glycine oxidase
IPCOMLNL_01630 7.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
IPCOMLNL_01631 5.2e-138 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IPCOMLNL_01632 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IPCOMLNL_01633 9.7e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IPCOMLNL_01634 1.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IPCOMLNL_01635 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IPCOMLNL_01636 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
IPCOMLNL_01637 1.6e-61 yjbL S Belongs to the UPF0738 family
IPCOMLNL_01638 2.7e-100 yjbK S protein conserved in bacteria
IPCOMLNL_01639 2.1e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IPCOMLNL_01640 4.8e-72 yjbI S Bacterial-like globin
IPCOMLNL_01641 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IPCOMLNL_01642 5.8e-19
IPCOMLNL_01643 0.0 pepF E oligoendopeptidase F
IPCOMLNL_01644 1.3e-218 yjbF S Competence protein
IPCOMLNL_01645 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IPCOMLNL_01646 5.6e-110 yjbE P Integral membrane protein TerC family
IPCOMLNL_01647 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IPCOMLNL_01648 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPCOMLNL_01649 2.2e-229 S Putative glycosyl hydrolase domain
IPCOMLNL_01650 1.1e-169 oppF E Belongs to the ABC transporter superfamily
IPCOMLNL_01651 2.7e-202 oppD P Belongs to the ABC transporter superfamily
IPCOMLNL_01652 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCOMLNL_01653 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCOMLNL_01654 0.0 oppA E ABC transporter substrate-binding protein
IPCOMLNL_01655 1.4e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IPCOMLNL_01656 5.5e-146 yjbA S Belongs to the UPF0736 family
IPCOMLNL_01657 2e-161 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCOMLNL_01658 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCOMLNL_01659 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
IPCOMLNL_01660 2.2e-187 appF E Belongs to the ABC transporter superfamily
IPCOMLNL_01661 9.7e-183 appD P Belongs to the ABC transporter superfamily
IPCOMLNL_01662 5.6e-149 yjaZ O Zn-dependent protease
IPCOMLNL_01663 4.4e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IPCOMLNL_01664 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPCOMLNL_01665 5.9e-32 yjzB
IPCOMLNL_01666 1.1e-26 comZ S ComZ
IPCOMLNL_01667 7.2e-166 med S Transcriptional activator protein med
IPCOMLNL_01668 3.6e-105 yjaV
IPCOMLNL_01669 6.4e-139 yjaU I carboxylic ester hydrolase activity
IPCOMLNL_01670 1.5e-23 yjzD S Protein of unknown function (DUF2929)
IPCOMLNL_01671 1.2e-27 yjzC S YjzC-like protein
IPCOMLNL_01672 1e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IPCOMLNL_01673 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
IPCOMLNL_01674 6.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IPCOMLNL_01675 2.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IPCOMLNL_01676 2.7e-135 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
IPCOMLNL_01677 3e-226 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IPCOMLNL_01678 8.6e-198 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IPCOMLNL_01679 1.2e-89 norB G Major Facilitator Superfamily
IPCOMLNL_01680 5.1e-271 yitY C D-arabinono-1,4-lactone oxidase
IPCOMLNL_01681 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
IPCOMLNL_01682 3.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
IPCOMLNL_01683 5.6e-152 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IPCOMLNL_01684 3.5e-07
IPCOMLNL_01685 4.4e-26 S Protein of unknown function (DUF3813)
IPCOMLNL_01686 6.5e-81 ipi S Intracellular proteinase inhibitor
IPCOMLNL_01687 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
IPCOMLNL_01688 5.5e-158 yitS S protein conserved in bacteria
IPCOMLNL_01690 3.1e-242 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
IPCOMLNL_01691 2e-228 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
IPCOMLNL_01692 1.8e-173 yufN S ABC transporter substrate-binding protein PnrA-like
IPCOMLNL_01693 1.8e-161 cvfB S protein conserved in bacteria
IPCOMLNL_01694 4e-52 yajQ S Belongs to the UPF0234 family
IPCOMLNL_01695 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IPCOMLNL_01696 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
IPCOMLNL_01697 2.2e-71 mcbG S Pentapeptide repeats (9 copies)
IPCOMLNL_01698 1.5e-83 yisT S DinB family
IPCOMLNL_01699 8.1e-156 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
IPCOMLNL_01700 4.1e-144 purR K helix_turn _helix lactose operon repressor
IPCOMLNL_01701 1.2e-157 yisR K Transcriptional regulator
IPCOMLNL_01702 9.7e-245 yisQ V Mate efflux family protein
IPCOMLNL_01703 1.9e-130 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
IPCOMLNL_01704 0.0 asnO 6.3.5.4 E Asparagine synthase
IPCOMLNL_01705 5.3e-98 yisN S Protein of unknown function (DUF2777)
IPCOMLNL_01706 3.2e-59 yisL S UPF0344 protein
IPCOMLNL_01707 1.2e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IPCOMLNL_01708 5e-07 yisI S Spo0E like sporulation regulatory protein
IPCOMLNL_01709 8.4e-34 gerPA S Spore germination protein
IPCOMLNL_01710 6.2e-35 gerPB S cell differentiation
IPCOMLNL_01711 9.1e-62 gerPC S Spore germination protein
IPCOMLNL_01712 3.1e-23 gerPD S Spore germination protein
IPCOMLNL_01713 1.1e-63 gerPE S Spore germination protein GerPE
IPCOMLNL_01714 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
IPCOMLNL_01715 1.1e-49 yisB V COG1403 Restriction endonuclease
IPCOMLNL_01716 0.0 sbcC L COG0419 ATPase involved in DNA repair
IPCOMLNL_01717 1.5e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IPCOMLNL_01718 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IPCOMLNL_01719 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
IPCOMLNL_01720 5.6e-124 ydfS S Protein of unknown function (DUF421)
IPCOMLNL_01721 9.7e-94 yhjR S Rubrerythrin
IPCOMLNL_01722 6.5e-108 K QacR-like protein, C-terminal region
IPCOMLNL_01723 2.1e-203 blt EGP Major facilitator Superfamily
IPCOMLNL_01724 2e-187 abrB S membrane
IPCOMLNL_01725 5.8e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
IPCOMLNL_01726 1.1e-275 yhjG CH FAD binding domain
IPCOMLNL_01727 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
IPCOMLNL_01728 2.2e-108 yhjE S SNARE associated Golgi protein
IPCOMLNL_01729 5e-60 yhjD
IPCOMLNL_01730 1.4e-27 yhjC S Protein of unknown function (DUF3311)
IPCOMLNL_01731 4.7e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPCOMLNL_01732 3.3e-47 S Belongs to the UPF0145 family
IPCOMLNL_01733 1.6e-42 yhjA S Excalibur calcium-binding domain
IPCOMLNL_01734 5.1e-125 yrpD S Domain of unknown function, YrpD
IPCOMLNL_01735 1.7e-90 mepB S MepB protein
IPCOMLNL_01736 1.4e-65 frataxin S Domain of unknown function (DU1801)
IPCOMLNL_01737 5.5e-37 frataxin S Domain of unknown function (DU1801)
IPCOMLNL_01738 1.9e-109 comK K Competence transcription factor
IPCOMLNL_01739 1.8e-31 yhzC S IDEAL
IPCOMLNL_01740 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCOMLNL_01741 4.8e-298 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
IPCOMLNL_01742 4.4e-199 hemAT NT chemotaxis protein
IPCOMLNL_01743 3.5e-89 bioY S BioY family
IPCOMLNL_01744 1.5e-277 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IPCOMLNL_01745 7.4e-200 vraB 2.3.1.9 I Belongs to the thiolase family
IPCOMLNL_01746 4.4e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
IPCOMLNL_01747 2.3e-151 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IPCOMLNL_01748 1.2e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
IPCOMLNL_01749 3.6e-235 yhfN 3.4.24.84 O Peptidase M48
IPCOMLNL_01750 1.9e-65 yhfM
IPCOMLNL_01751 1.1e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IPCOMLNL_01752 8.5e-111 yhfK GM NmrA-like family
IPCOMLNL_01753 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
IPCOMLNL_01754 2.9e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IPCOMLNL_01755 7.9e-11 yhfH S YhfH-like protein
IPCOMLNL_01756 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPCOMLNL_01757 2.5e-197 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
IPCOMLNL_01759 3.7e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPCOMLNL_01760 4.1e-272 yhgE S YhgE Pip N-terminal domain protein
IPCOMLNL_01761 3.2e-101 yhgD K Transcriptional regulator
IPCOMLNL_01762 2e-274 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IPCOMLNL_01763 2.1e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IPCOMLNL_01764 4.3e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IPCOMLNL_01765 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IPCOMLNL_01766 6.4e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IPCOMLNL_01767 2e-242 yhfA C membrane
IPCOMLNL_01768 1.2e-222 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IPCOMLNL_01769 3.6e-123 ecsC S EcsC protein family
IPCOMLNL_01770 8.5e-221 ecsB U ABC transporter
IPCOMLNL_01771 1.1e-135 ecsA V transporter (ATP-binding protein)
IPCOMLNL_01772 2.6e-79 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IPCOMLNL_01773 9.2e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IPCOMLNL_01774 1.4e-76 trpP S Tryptophan transporter TrpP
IPCOMLNL_01775 2e-17
IPCOMLNL_01776 2.4e-38 yhaH S YtxH-like protein
IPCOMLNL_01777 3.3e-112 hpr K Negative regulator of protease production and sporulation
IPCOMLNL_01778 9.9e-55 yhaI S Protein of unknown function (DUF1878)
IPCOMLNL_01779 7e-95 yhaK S Putative zincin peptidase
IPCOMLNL_01780 4.5e-120 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IPCOMLNL_01781 1.6e-32 yhaL S Sporulation protein YhaL
IPCOMLNL_01782 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
IPCOMLNL_01783 0.0 yhaN L AAA domain
IPCOMLNL_01784 1.2e-235 yhaO L DNA repair exonuclease
IPCOMLNL_01785 6.8e-205 yhaP CP COG1668 ABC-type Na efflux pump, permease component
IPCOMLNL_01786 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
IPCOMLNL_01787 7.3e-15 S YhzD-like protein
IPCOMLNL_01788 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
IPCOMLNL_01790 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
IPCOMLNL_01791 9.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
IPCOMLNL_01792 9.2e-250 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
IPCOMLNL_01793 9.3e-294 hemZ H coproporphyrinogen III oxidase
IPCOMLNL_01794 3.3e-158 yhaX S haloacid dehalogenase-like hydrolase
IPCOMLNL_01795 1.1e-201 yhaZ L DNA alkylation repair enzyme
IPCOMLNL_01796 4.4e-53 yheA S Belongs to the UPF0342 family
IPCOMLNL_01797 4.2e-206 yheB S Belongs to the UPF0754 family
IPCOMLNL_01798 1.8e-214 yheC HJ YheC/D like ATP-grasp
IPCOMLNL_01799 5.1e-259 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
IPCOMLNL_01800 1.7e-36 yheE S Family of unknown function (DUF5342)
IPCOMLNL_01801 7.6e-29 sspB S spore protein
IPCOMLNL_01803 3.7e-111 yheG GM NAD(P)H-binding
IPCOMLNL_01804 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
IPCOMLNL_01805 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
IPCOMLNL_01807 2.1e-85 T universal stress protein
IPCOMLNL_01808 3.1e-93 ymcC S Membrane
IPCOMLNL_01809 3e-87 pksA K Transcriptional regulator
IPCOMLNL_01810 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IPCOMLNL_01811 3e-156 yheN G deacetylase
IPCOMLNL_01812 4.5e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IPCOMLNL_01813 4.6e-205 yhdY M Mechanosensitive ion channel
IPCOMLNL_01815 6.5e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IPCOMLNL_01816 4.9e-61 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPCOMLNL_01817 5.1e-49 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPCOMLNL_01818 2.9e-257 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
IPCOMLNL_01819 4.3e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IPCOMLNL_01820 3.2e-225 yhdR 2.6.1.1 E Aminotransferase
IPCOMLNL_01821 4.3e-71 cueR K transcriptional
IPCOMLNL_01822 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IPCOMLNL_01823 1.9e-109 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IPCOMLNL_01824 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
IPCOMLNL_01825 6.6e-201 yhdL S Sigma factor regulator N-terminal
IPCOMLNL_01826 8.1e-45 yhdK S Sigma-M inhibitor protein
IPCOMLNL_01827 4.4e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IPCOMLNL_01828 2e-250 yhdG E amino acid
IPCOMLNL_01829 6.6e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCOMLNL_01830 1.3e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
IPCOMLNL_01831 2e-163 citR K Transcriptional regulator
IPCOMLNL_01832 6.3e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IPCOMLNL_01833 6.8e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
IPCOMLNL_01834 3.6e-271 ycgB S Stage V sporulation protein R
IPCOMLNL_01835 4.5e-256 ygxB M Conserved TM helix
IPCOMLNL_01836 5.6e-74 nsrR K Transcriptional regulator
IPCOMLNL_01837 4.7e-218 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IPCOMLNL_01838 9e-53 yhdC S Protein of unknown function (DUF3889)
IPCOMLNL_01839 2.5e-39 yhdB S YhdB-like protein
IPCOMLNL_01840 9.7e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
IPCOMLNL_01841 1.4e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPCOMLNL_01842 3.2e-206 yhcY 2.7.13.3 T Histidine kinase
IPCOMLNL_01843 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IPCOMLNL_01844 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IPCOMLNL_01845 7e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IPCOMLNL_01846 1.9e-147 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
IPCOMLNL_01847 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IPCOMLNL_01848 1.9e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPCOMLNL_01849 1.1e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IPCOMLNL_01850 4.9e-125 yhcW 5.4.2.6 S hydrolase
IPCOMLNL_01851 2.6e-68 yhcV S COG0517 FOG CBS domain
IPCOMLNL_01852 1.3e-69 yhcU S Family of unknown function (DUF5365)
IPCOMLNL_01853 1.1e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IPCOMLNL_01854 1.5e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
IPCOMLNL_01855 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
IPCOMLNL_01856 7.6e-115 yhcQ M Spore coat protein
IPCOMLNL_01857 3.3e-161 yhcP
IPCOMLNL_01858 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IPCOMLNL_01859 3.9e-51 yhcM
IPCOMLNL_01860 7.1e-221 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPCOMLNL_01861 1e-185 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
IPCOMLNL_01862 4.2e-147 metQ M Belongs to the nlpA lipoprotein family
IPCOMLNL_01863 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
IPCOMLNL_01864 3.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IPCOMLNL_01865 4.1e-167 yhcH V ABC transporter, ATP-binding protein
IPCOMLNL_01866 1.6e-126 yhcG V ABC transporter, ATP-binding protein
IPCOMLNL_01867 4.7e-61 yhcF K Transcriptional regulator
IPCOMLNL_01868 6.2e-52
IPCOMLNL_01869 7.2e-54 yhcC
IPCOMLNL_01870 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
IPCOMLNL_01871 8.4e-285 yhcA EGP Major facilitator Superfamily
IPCOMLNL_01872 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
IPCOMLNL_01873 4.6e-74 yhbI K DNA-binding transcription factor activity
IPCOMLNL_01874 3e-215 yhbH S Belongs to the UPF0229 family
IPCOMLNL_01875 0.0 prkA T Ser protein kinase
IPCOMLNL_01877 4.2e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
IPCOMLNL_01878 2.3e-61 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
IPCOMLNL_01879 5e-108 yhbD K Protein of unknown function (DUF4004)
IPCOMLNL_01880 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IPCOMLNL_01881 8.8e-173 yhbB S Putative amidase domain
IPCOMLNL_01882 7.8e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IPCOMLNL_01883 7.2e-107 yhzB S B3/4 domain
IPCOMLNL_01885 4.8e-23 K Transcriptional regulator
IPCOMLNL_01886 8.6e-81 ygaO
IPCOMLNL_01887 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPCOMLNL_01888 8.5e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
IPCOMLNL_01889 2.2e-143 ssuC P ABC transporter (permease)
IPCOMLNL_01890 1.9e-178 ssuA M Sulfonate ABC transporter
IPCOMLNL_01891 6.1e-140 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IPCOMLNL_01892 2.5e-180 S Amidohydrolase
IPCOMLNL_01893 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IPCOMLNL_01894 9e-133 oppF3 E Belongs to the ABC transporter superfamily
IPCOMLNL_01895 4.4e-135 oppD3 P Belongs to the ABC transporter superfamily
IPCOMLNL_01896 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPCOMLNL_01897 3.7e-147 appB P Binding-protein-dependent transport system inner membrane component
IPCOMLNL_01898 9.8e-231 oppA5 E PFAM extracellular solute-binding protein family 5
IPCOMLNL_01900 5.9e-263 ygaK C Berberine and berberine like
IPCOMLNL_01901 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IPCOMLNL_01902 1.5e-132 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
IPCOMLNL_01903 1.3e-282 C Na+/H+ antiporter family
IPCOMLNL_01907 1.6e-08
IPCOMLNL_01915 7.8e-08
IPCOMLNL_01920 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_01921 1.4e-33 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IPCOMLNL_01923 3.4e-39 S COG NOG14552 non supervised orthologous group
IPCOMLNL_01924 2.3e-28 K helix_turn_helix, Lux Regulon
IPCOMLNL_01925 1.2e-33 3.4.21.102 M Peptidase family S41
IPCOMLNL_01927 9.4e-141 V Beta-lactamase enzyme family
IPCOMLNL_01928 1.3e-81 ymdC 2.7.1.95 J Phosphotransferase enzyme family
IPCOMLNL_01929 5.8e-124 L Molecular Function DNA binding, Biological Process DNA recombination
IPCOMLNL_01930 1.4e-45 L COG2963 Transposase and inactivated derivatives
IPCOMLNL_01931 0.0 fusAA Q Non-ribosomal peptide synthetase modules and related proteins
IPCOMLNL_01932 2.6e-65 IQ KR domain
IPCOMLNL_01934 8.6e-20 L Transposase and inactivated derivatives
IPCOMLNL_01936 1.3e-218 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPCOMLNL_01937 1.5e-55 swrA S Swarming motility protein
IPCOMLNL_01938 3e-254 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
IPCOMLNL_01939 3.1e-227 ywoF P Right handed beta helix region
IPCOMLNL_01940 9.2e-156 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IPCOMLNL_01941 1e-122 ftsE D cell division ATP-binding protein FtsE
IPCOMLNL_01942 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
IPCOMLNL_01943 2.1e-149 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
IPCOMLNL_01944 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IPCOMLNL_01945 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IPCOMLNL_01946 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IPCOMLNL_01947 6.8e-68
IPCOMLNL_01948 2.6e-10 fliT S bacterial-type flagellum organization
IPCOMLNL_01949 3e-66 fliS N flagellar protein FliS
IPCOMLNL_01950 6.2e-245 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IPCOMLNL_01951 1.6e-100 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IPCOMLNL_01952 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IPCOMLNL_01953 1.6e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IPCOMLNL_01954 3.4e-79 yviE
IPCOMLNL_01955 6.1e-163 flgL N Belongs to the bacterial flagellin family
IPCOMLNL_01956 2.8e-274 flgK N flagellar hook-associated protein
IPCOMLNL_01957 8.9e-81 flgN NOU FlgN protein
IPCOMLNL_01958 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
IPCOMLNL_01959 2.4e-74 yvyF S flagellar protein
IPCOMLNL_01960 4.5e-77 comFC S Phosphoribosyl transferase domain
IPCOMLNL_01961 1.7e-42 comFB S Late competence development protein ComFB
IPCOMLNL_01962 3.4e-258 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IPCOMLNL_01963 1.4e-158 degV S protein conserved in bacteria
IPCOMLNL_01964 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPCOMLNL_01965 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IPCOMLNL_01966 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
IPCOMLNL_01967 7.8e-166 yvhJ K Transcriptional regulator
IPCOMLNL_01968 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IPCOMLNL_01969 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
IPCOMLNL_01970 6.8e-144 tuaG GT2 M Glycosyltransferase like family 2
IPCOMLNL_01971 1.2e-115 tuaF M protein involved in exopolysaccharide biosynthesis
IPCOMLNL_01972 1.1e-240 tuaE M Teichuronic acid biosynthesis protein
IPCOMLNL_01973 2.4e-248 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IPCOMLNL_01974 1.4e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
IPCOMLNL_01975 1e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPCOMLNL_01976 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IPCOMLNL_01977 3.1e-209 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IPCOMLNL_01978 1e-306 lytB 3.5.1.28 D Stage II sporulation protein
IPCOMLNL_01979 5.9e-30
IPCOMLNL_01980 2.9e-136 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IPCOMLNL_01981 1.7e-183 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IPCOMLNL_01982 3.7e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IPCOMLNL_01983 1.9e-180 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IPCOMLNL_01984 9.8e-136 tagG GM Transport permease protein
IPCOMLNL_01985 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IPCOMLNL_01986 4.3e-246 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
IPCOMLNL_01987 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
IPCOMLNL_01988 6.5e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IPCOMLNL_01989 3.2e-209 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IPCOMLNL_01990 2.6e-129 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IPCOMLNL_01991 9e-186 pmi 5.3.1.8 G mannose-6-phosphate isomerase
IPCOMLNL_01992 5.7e-264 gerBA EG Spore germination protein
IPCOMLNL_01993 1.5e-195 gerBB E Spore germination protein
IPCOMLNL_01994 2.5e-211 gerAC S Spore germination protein
IPCOMLNL_01995 2.6e-266 GT2,GT4 J Glycosyl transferase family 2
IPCOMLNL_01996 3.7e-249 ywtG EGP Major facilitator Superfamily
IPCOMLNL_01997 7.2e-178 ywtF K Transcriptional regulator
IPCOMLNL_01998 4.7e-157 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
IPCOMLNL_01999 2.6e-36 yttA 2.7.13.3 S Pfam Transposase IS66
IPCOMLNL_02000 1.8e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IPCOMLNL_02001 1.3e-20 ywtC
IPCOMLNL_02002 1.2e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IPCOMLNL_02003 2.3e-70 pgsC S biosynthesis protein
IPCOMLNL_02004 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
IPCOMLNL_02005 2e-184 gerKA EG Spore germination protein
IPCOMLNL_02006 6.7e-193 gerKB E Spore germination protein
IPCOMLNL_02007 4.8e-202 gerKC S Spore germination B3/ GerAC like, C-terminal
IPCOMLNL_02008 1.3e-179 rbsR K transcriptional
IPCOMLNL_02009 5.7e-158 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPCOMLNL_02010 9.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IPCOMLNL_02011 1.7e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IPCOMLNL_02012 3.8e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
IPCOMLNL_02013 9.7e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
IPCOMLNL_02014 5.2e-90 batE T Sh3 type 3 domain protein
IPCOMLNL_02015 1.2e-94 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
IPCOMLNL_02016 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
IPCOMLNL_02017 2.4e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IPCOMLNL_02018 9e-167 alsR K LysR substrate binding domain
IPCOMLNL_02020 1.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IPCOMLNL_02021 4.4e-126 ywrJ
IPCOMLNL_02022 3.5e-131 cotB
IPCOMLNL_02023 7.2e-211 cotH M Spore Coat
IPCOMLNL_02024 2.2e-09
IPCOMLNL_02025 5.6e-112 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IPCOMLNL_02026 3.6e-07 S Domain of unknown function (DUF4181)
IPCOMLNL_02027 4.2e-305 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IPCOMLNL_02028 3.2e-83 ywrC K Transcriptional regulator
IPCOMLNL_02029 5.9e-103 ywrB P Chromate transporter
IPCOMLNL_02030 2.2e-88 ywrA P COG2059 Chromate transport protein ChrA
IPCOMLNL_02032 6.7e-93 ywqN S NAD(P)H-dependent
IPCOMLNL_02033 1.8e-156 K Transcriptional regulator
IPCOMLNL_02034 1.4e-119 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IPCOMLNL_02035 8.7e-25
IPCOMLNL_02036 3.6e-239 ywqJ S Pre-toxin TG
IPCOMLNL_02037 4.3e-37 ywqI S Family of unknown function (DUF5344)
IPCOMLNL_02038 1.9e-21 S Domain of unknown function (DUF5082)
IPCOMLNL_02040 1.3e-148 ywqG S Domain of unknown function (DUF1963)
IPCOMLNL_02041 1.2e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IPCOMLNL_02042 1.6e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
IPCOMLNL_02043 5.7e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
IPCOMLNL_02044 4.4e-111 ywqC M biosynthesis protein
IPCOMLNL_02045 1.3e-14
IPCOMLNL_02046 3.9e-306 ywqB S SWIM zinc finger
IPCOMLNL_02047 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IPCOMLNL_02048 1.5e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
IPCOMLNL_02049 7.5e-138 glcR K DeoR C terminal sensor domain
IPCOMLNL_02050 3.7e-57 ssbB L Single-stranded DNA-binding protein
IPCOMLNL_02051 4e-62 ywpG
IPCOMLNL_02052 1.1e-68 ywpF S YwpF-like protein
IPCOMLNL_02053 4.1e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IPCOMLNL_02054 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IPCOMLNL_02055 5.5e-200 S aspartate phosphatase
IPCOMLNL_02056 1.1e-142 flhP N flagellar basal body
IPCOMLNL_02057 3.2e-128 flhO N flagellar basal body
IPCOMLNL_02058 2.7e-180 mbl D Rod shape-determining protein
IPCOMLNL_02059 1.8e-44 spoIIID K Stage III sporulation protein D
IPCOMLNL_02060 8.5e-72 ywoH K transcriptional
IPCOMLNL_02061 4.9e-213 ywoG EGP Major facilitator Superfamily
IPCOMLNL_02062 1.6e-274 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
IPCOMLNL_02063 3.6e-244 ywoD EGP Major facilitator superfamily
IPCOMLNL_02064 5.7e-103 phzA Q Isochorismatase family
IPCOMLNL_02065 2.5e-228 amt P Ammonium transporter
IPCOMLNL_02066 1.7e-57 nrgB K Belongs to the P(II) protein family
IPCOMLNL_02067 1.1e-209 ftsW D Belongs to the SEDS family
IPCOMLNL_02068 3.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
IPCOMLNL_02069 3.3e-71 ywnJ S VanZ like family
IPCOMLNL_02070 8.4e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
IPCOMLNL_02071 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
IPCOMLNL_02072 1.2e-10 ywnC S Family of unknown function (DUF5362)
IPCOMLNL_02073 2.7e-68 ywnF S Family of unknown function (DUF5392)
IPCOMLNL_02074 8.4e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPCOMLNL_02075 1.2e-51 ywnC S Family of unknown function (DUF5362)
IPCOMLNL_02076 9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
IPCOMLNL_02077 1.8e-66 ywnA K Transcriptional regulator
IPCOMLNL_02078 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IPCOMLNL_02079 7.2e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IPCOMLNL_02080 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IPCOMLNL_02082 2.1e-82 ywmF S Peptidase M50
IPCOMLNL_02083 1.5e-94 S response regulator aspartate phosphatase
IPCOMLNL_02084 4.1e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IPCOMLNL_02085 3.8e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IPCOMLNL_02087 3e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
IPCOMLNL_02088 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
IPCOMLNL_02089 7.3e-189 spoIID D Stage II sporulation protein D
IPCOMLNL_02090 5.2e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPCOMLNL_02091 2.4e-133 ywmB S TATA-box binding
IPCOMLNL_02092 1.3e-32 ywzB S membrane
IPCOMLNL_02093 3.5e-90 ywmA
IPCOMLNL_02094 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IPCOMLNL_02095 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IPCOMLNL_02096 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IPCOMLNL_02097 4.1e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPCOMLNL_02098 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPCOMLNL_02099 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IPCOMLNL_02100 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPCOMLNL_02101 9.3e-130 atpB C it plays a direct role in the translocation of protons across the membrane
IPCOMLNL_02102 2.1e-61 atpI S ATP synthase
IPCOMLNL_02103 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IPCOMLNL_02104 7.3e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IPCOMLNL_02105 1.7e-96 ywlG S Belongs to the UPF0340 family
IPCOMLNL_02106 5.4e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
IPCOMLNL_02107 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPCOMLNL_02108 2e-84 mntP P Probably functions as a manganese efflux pump
IPCOMLNL_02109 2.5e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IPCOMLNL_02110 1.8e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
IPCOMLNL_02111 4.4e-110 spoIIR S stage II sporulation protein R
IPCOMLNL_02112 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
IPCOMLNL_02114 1.6e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IPCOMLNL_02115 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IPCOMLNL_02116 6.4e-66 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPCOMLNL_02117 9.7e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IPCOMLNL_02118 3.6e-158 ywkB S Membrane transport protein
IPCOMLNL_02119 0.0 sfcA 1.1.1.38 C malic enzyme
IPCOMLNL_02120 4.6e-103 tdk 2.7.1.21 F thymidine kinase
IPCOMLNL_02121 1.1e-32 rpmE J Binds the 23S rRNA
IPCOMLNL_02122 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IPCOMLNL_02123 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
IPCOMLNL_02124 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPCOMLNL_02125 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IPCOMLNL_02126 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
IPCOMLNL_02127 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
IPCOMLNL_02128 4.9e-93 ywjG S Domain of unknown function (DUF2529)
IPCOMLNL_02129 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IPCOMLNL_02130 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IPCOMLNL_02131 0.0 fadF C COG0247 Fe-S oxidoreductase
IPCOMLNL_02132 3.9e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IPCOMLNL_02133 1.6e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IPCOMLNL_02134 4.2e-43 ywjC
IPCOMLNL_02135 0.0 ywjA V ABC transporter
IPCOMLNL_02136 1.7e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPCOMLNL_02137 4.9e-103 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IPCOMLNL_02138 1.5e-123 narI 1.7.5.1 C nitrate reductase, gamma
IPCOMLNL_02139 2.1e-94 narJ 1.7.5.1 C nitrate reductase
IPCOMLNL_02140 1.1e-294 narH 1.7.5.1 C Nitrate reductase, beta
IPCOMLNL_02141 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IPCOMLNL_02142 3.8e-84 arfM T cyclic nucleotide binding
IPCOMLNL_02143 3.1e-138 ywiC S YwiC-like protein
IPCOMLNL_02144 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
IPCOMLNL_02145 5.8e-214 narK P COG2223 Nitrate nitrite transporter
IPCOMLNL_02146 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IPCOMLNL_02147 1.1e-42 ywiB S protein conserved in bacteria
IPCOMLNL_02148 6.4e-77 S aspartate phosphatase
IPCOMLNL_02150 2.2e-28 ydcG K sequence-specific DNA binding
IPCOMLNL_02151 5e-33
IPCOMLNL_02152 7.5e-28 S Domain of unknown function (DUF4177)
IPCOMLNL_02154 6.8e-76 CP Membrane
IPCOMLNL_02157 5.4e-169 speB 3.5.3.11 E Belongs to the arginase family
IPCOMLNL_02158 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IPCOMLNL_02159 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IPCOMLNL_02160 1.5e-82
IPCOMLNL_02161 2.4e-95 ywhD S YwhD family
IPCOMLNL_02162 1.2e-117 ywhC S Peptidase family M50
IPCOMLNL_02163 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
IPCOMLNL_02164 5.2e-69 ywhA K Transcriptional regulator
IPCOMLNL_02165 1.5e-246 yhdG_1 E C-terminus of AA_permease
IPCOMLNL_02166 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
IPCOMLNL_02167 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
IPCOMLNL_02168 6.9e-36 ywzC S Belongs to the UPF0741 family
IPCOMLNL_02169 3e-110 rsfA_1
IPCOMLNL_02170 5.3e-50 padR K PadR family transcriptional regulator
IPCOMLNL_02171 1.8e-93 S membrane
IPCOMLNL_02172 3.8e-165 V ABC transporter, ATP-binding protein
IPCOMLNL_02173 1.1e-167 yhcI S ABC transporter (permease)
IPCOMLNL_02176 1.5e-177
IPCOMLNL_02178 1.2e-157 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IPCOMLNL_02179 1.1e-161 cysL K Transcriptional regulator
IPCOMLNL_02180 4e-157 MA20_14895 S Conserved hypothetical protein 698
IPCOMLNL_02181 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
IPCOMLNL_02182 2.5e-146 ywfI C May function as heme-dependent peroxidase
IPCOMLNL_02183 3.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
IPCOMLNL_02184 3.5e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
IPCOMLNL_02185 1.2e-206 bacE EGP Major facilitator Superfamily
IPCOMLNL_02186 2.2e-268 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IPCOMLNL_02187 3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCOMLNL_02188 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IPCOMLNL_02189 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IPCOMLNL_02190 2.7e-222 ywfA EGP Major facilitator Superfamily
IPCOMLNL_02191 5.3e-207 tcaB EGP Major facilitator Superfamily
IPCOMLNL_02192 7.5e-261 lysP E amino acid
IPCOMLNL_02193 0.0 rocB E arginine degradation protein
IPCOMLNL_02194 2.3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IPCOMLNL_02195 2.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IPCOMLNL_02196 3.5e-158 T PhoQ Sensor
IPCOMLNL_02197 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCOMLNL_02198 1.6e-75
IPCOMLNL_02199 1.1e-119 S ABC-2 family transporter protein
IPCOMLNL_02200 4.3e-172 bcrA5 V ABC transporter, ATP-binding protein
IPCOMLNL_02201 3.5e-87 spsL 5.1.3.13 M Spore Coat
IPCOMLNL_02202 3.6e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IPCOMLNL_02203 6.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IPCOMLNL_02204 1.6e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IPCOMLNL_02205 2.6e-183 spsG M Spore Coat
IPCOMLNL_02206 4.5e-132 spsF M Spore Coat
IPCOMLNL_02207 9.9e-216 spsE 2.5.1.56 M acid synthase
IPCOMLNL_02208 1.9e-158 spsD 2.3.1.210 K Spore Coat
IPCOMLNL_02209 4.8e-221 spsC E Belongs to the DegT DnrJ EryC1 family
IPCOMLNL_02210 9.1e-275 spsB M Capsule polysaccharide biosynthesis protein
IPCOMLNL_02211 2.6e-143 spsA M Spore Coat
IPCOMLNL_02212 2.3e-54 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IPCOMLNL_02213 4.2e-46 ywdK S small membrane protein
IPCOMLNL_02214 1.8e-229 ywdJ F Xanthine uracil
IPCOMLNL_02215 7.3e-41 ywdI S Family of unknown function (DUF5327)
IPCOMLNL_02216 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IPCOMLNL_02217 5e-153 ywdF GT2,GT4 S Glycosyltransferase like family 2
IPCOMLNL_02219 2.6e-88 ywdD
IPCOMLNL_02220 6.3e-57 pex K Transcriptional regulator PadR-like family
IPCOMLNL_02221 1.9e-144 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IPCOMLNL_02222 9.7e-20 ywdA
IPCOMLNL_02223 6.8e-286 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
IPCOMLNL_02224 2.4e-248 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IPCOMLNL_02225 2e-07 sacT K transcriptional antiterminator
IPCOMLNL_02226 1.4e-150 sacT K transcriptional antiterminator
IPCOMLNL_02228 0.0 vpr O Belongs to the peptidase S8 family
IPCOMLNL_02229 2.3e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCOMLNL_02230 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
IPCOMLNL_02231 1e-207 rodA D Belongs to the SEDS family
IPCOMLNL_02232 7e-79 ysnE K acetyltransferase
IPCOMLNL_02233 3e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
IPCOMLNL_02234 9.9e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
IPCOMLNL_02235 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
IPCOMLNL_02236 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IPCOMLNL_02237 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IPCOMLNL_02238 4.2e-26 ywzA S membrane
IPCOMLNL_02239 1.8e-292 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IPCOMLNL_02240 5.9e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IPCOMLNL_02241 2.3e-61 gtcA S GtrA-like protein
IPCOMLNL_02242 4.3e-112 ywcC K Bacterial regulatory proteins, tetR family
IPCOMLNL_02244 8e-128 H Methionine biosynthesis protein MetW
IPCOMLNL_02245 5.3e-132 S Streptomycin biosynthesis protein StrF
IPCOMLNL_02246 1.1e-85 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IPCOMLNL_02247 7.1e-239 ywbN P Dyp-type peroxidase family protein
IPCOMLNL_02248 1.2e-112 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IPCOMLNL_02249 6.9e-134 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IPCOMLNL_02250 8.2e-152 ywbI K Transcriptional regulator
IPCOMLNL_02251 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IPCOMLNL_02252 3.4e-110 ywbG M effector of murein hydrolase
IPCOMLNL_02253 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
IPCOMLNL_02254 1.6e-140 mta K transcriptional
IPCOMLNL_02255 1.5e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
IPCOMLNL_02256 5.7e-222 ywbD 2.1.1.191 J Methyltransferase
IPCOMLNL_02257 4.9e-66 ywbC 4.4.1.5 E glyoxalase
IPCOMLNL_02258 7.1e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPCOMLNL_02259 1.6e-265 epr 3.4.21.62 O Belongs to the peptidase S8 family
IPCOMLNL_02260 1.1e-163 gspA M General stress
IPCOMLNL_02261 1.6e-48 ywaE K Transcriptional regulator
IPCOMLNL_02262 3.9e-197 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPCOMLNL_02263 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
IPCOMLNL_02264 1.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
IPCOMLNL_02265 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
IPCOMLNL_02266 3.5e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_02267 3.7e-229 dltB M membrane protein involved in D-alanine export
IPCOMLNL_02268 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_02269 1.8e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IPCOMLNL_02270 7.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IPCOMLNL_02271 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IPCOMLNL_02272 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
IPCOMLNL_02273 2.8e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPCOMLNL_02274 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
IPCOMLNL_02275 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
IPCOMLNL_02277 3.6e-108 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IPCOMLNL_02278 7.3e-173 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCOMLNL_02279 1.3e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCOMLNL_02280 1.5e-166 cbrA3 P Periplasmic binding protein
IPCOMLNL_02281 1.6e-58 arsR K transcriptional
IPCOMLNL_02282 2.1e-225 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IPCOMLNL_02283 9e-50 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
IPCOMLNL_02284 1.7e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
IPCOMLNL_02285 1.1e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPCOMLNL_02286 1.1e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IPCOMLNL_02287 2.1e-165 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
IPCOMLNL_02288 9.9e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
IPCOMLNL_02289 9.2e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
IPCOMLNL_02290 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IPCOMLNL_02291 1.6e-193 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IPCOMLNL_02292 1e-251 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
IPCOMLNL_02293 2.5e-155 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IPCOMLNL_02294 3.8e-291 cydD V ATP-binding protein
IPCOMLNL_02295 9.4e-311 cydD V ATP-binding
IPCOMLNL_02296 5.5e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
IPCOMLNL_02297 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
IPCOMLNL_02298 1.5e-215 cimH C COG3493 Na citrate symporter
IPCOMLNL_02299 2.3e-156 yxkH G Polysaccharide deacetylase
IPCOMLNL_02300 3.5e-205 msmK P Belongs to the ABC transporter superfamily
IPCOMLNL_02301 8.8e-167 lrp QT PucR C-terminal helix-turn-helix domain
IPCOMLNL_02302 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IPCOMLNL_02303 7.1e-86 yxkC S Domain of unknown function (DUF4352)
IPCOMLNL_02304 2.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IPCOMLNL_02305 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IPCOMLNL_02308 3.5e-85 yxjI S LURP-one-related
IPCOMLNL_02309 2.8e-218 yxjG 2.1.1.14 E Methionine synthase
IPCOMLNL_02310 6.9e-156 rlmA 2.1.1.187 Q Methyltransferase domain
IPCOMLNL_02311 4.3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IPCOMLNL_02312 2.7e-75 T Domain of unknown function (DUF4163)
IPCOMLNL_02313 8.2e-45 yxiS
IPCOMLNL_02314 2.5e-177 L DNA synthesis involved in DNA repair
IPCOMLNL_02315 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
IPCOMLNL_02316 4.7e-222 citH C Citrate transporter
IPCOMLNL_02317 7.3e-143 exoK GH16 M licheninase activity
IPCOMLNL_02318 1e-148 licT K transcriptional antiterminator
IPCOMLNL_02319 8.7e-221 yxiO S COG2270 Permeases of the major facilitator superfamily
IPCOMLNL_02320 5.3e-262 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IPCOMLNL_02323 1.9e-59 S SMI1-KNR4 cell-wall
IPCOMLNL_02324 1.3e-79 yxiI S Protein of unknown function (DUF2716)
IPCOMLNL_02325 6.1e-18
IPCOMLNL_02326 4.4e-12 S YxiJ-like protein
IPCOMLNL_02327 1e-111
IPCOMLNL_02328 6e-79
IPCOMLNL_02329 3.9e-25
IPCOMLNL_02332 4.9e-64 yxiG
IPCOMLNL_02333 2.2e-59 yxxG
IPCOMLNL_02334 7.2e-08
IPCOMLNL_02335 1.8e-19
IPCOMLNL_02338 3.3e-52
IPCOMLNL_02339 0.0 wapA M COG3209 Rhs family protein
IPCOMLNL_02340 1.9e-200 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
IPCOMLNL_02341 1.2e-147 yxxF EG EamA-like transporter family
IPCOMLNL_02342 4.9e-73 yxiE T Belongs to the universal stress protein A family
IPCOMLNL_02343 0.0 L HKD family nuclease
IPCOMLNL_02344 1.1e-60 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IPCOMLNL_02345 1.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IPCOMLNL_02346 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IPCOMLNL_02347 9.4e-208 hutH 4.3.1.3 E Histidine ammonia-lyase
IPCOMLNL_02348 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IPCOMLNL_02349 4.4e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
IPCOMLNL_02350 8.5e-176 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IPCOMLNL_02351 8e-247 lysP E amino acid
IPCOMLNL_02352 1.2e-28 yhaP CP COG1668 ABC-type Na efflux pump, permease component
IPCOMLNL_02353 1.8e-90 yhaQ S abc transporter atp-binding protein
IPCOMLNL_02354 2e-57 IQ Enoyl-(Acyl carrier protein) reductase
IPCOMLNL_02355 1.3e-08 yydH S Psort location CytoplasmicMembrane, score 10.00
IPCOMLNL_02356 1.1e-85 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
IPCOMLNL_02357 6.4e-30 tehB 2.1.1.265 Q methyltransferase
IPCOMLNL_02358 1.3e-40
IPCOMLNL_02362 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
IPCOMLNL_02363 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IPCOMLNL_02364 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IPCOMLNL_02365 8.1e-171 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IPCOMLNL_02366 1.8e-150 yidA S hydrolases of the HAD superfamily
IPCOMLNL_02369 2.1e-08 yxeE
IPCOMLNL_02370 8.4e-23 yxeD
IPCOMLNL_02371 6e-35
IPCOMLNL_02372 1.4e-178 fhuD P Periplasmic binding protein
IPCOMLNL_02373 1.3e-57 yxeA S Protein of unknown function (DUF1093)
IPCOMLNL_02374 0.0 yxdM V ABC transporter (permease)
IPCOMLNL_02375 5.5e-141 yxdL V ABC transporter, ATP-binding protein
IPCOMLNL_02376 6e-177 T PhoQ Sensor
IPCOMLNL_02377 1.8e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCOMLNL_02378 8.6e-273 T Histidine kinase
IPCOMLNL_02379 9.1e-138 T Transcriptional regulator
IPCOMLNL_02380 3e-162 bcrA V ABC transporter, ATP-binding protein
IPCOMLNL_02381 1.3e-131 S permease
IPCOMLNL_02382 3.9e-128 S ABC-2 family transporter protein
IPCOMLNL_02383 2.1e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IPCOMLNL_02384 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IPCOMLNL_02385 1.1e-166 iolH G Xylose isomerase-like TIM barrel
IPCOMLNL_02386 2.6e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IPCOMLNL_02387 4.8e-230 iolF EGP Major facilitator Superfamily
IPCOMLNL_02388 2e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IPCOMLNL_02389 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IPCOMLNL_02390 1.7e-182 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IPCOMLNL_02391 7.6e-157 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IPCOMLNL_02392 1.8e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IPCOMLNL_02393 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
IPCOMLNL_02394 4.9e-176 iolS C Aldo keto reductase
IPCOMLNL_02395 6.7e-246 csbC EGP Major facilitator Superfamily
IPCOMLNL_02396 0.0 htpG O Molecular chaperone. Has ATPase activity
IPCOMLNL_02398 2.1e-151 IQ Enoyl-(Acyl carrier protein) reductase
IPCOMLNL_02399 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPCOMLNL_02400 1e-199 desK 2.7.13.3 T Histidine kinase
IPCOMLNL_02401 6e-199 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
IPCOMLNL_02402 9.2e-217 yxbF K Bacterial regulatory proteins, tetR family
IPCOMLNL_02403 2.5e-250 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IPCOMLNL_02404 8e-142 S PQQ-like domain
IPCOMLNL_02405 3e-64 S Family of unknown function (DUF5391)
IPCOMLNL_02406 5.1e-50 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
IPCOMLNL_02407 2.9e-202 EGP Major facilitator Superfamily
IPCOMLNL_02408 7.6e-74 yxaI S membrane protein domain
IPCOMLNL_02409 2e-126 E Ring-cleavage extradiol dioxygenase
IPCOMLNL_02410 1.3e-21 3.4.24.84 O metalloendopeptidase activity
IPCOMLNL_02411 2.1e-91 mrr V Mrr N-terminal domain
IPCOMLNL_02412 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
IPCOMLNL_02413 5e-287 ahpF O Alkyl hydroperoxide reductase
IPCOMLNL_02415 5.1e-243 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
IPCOMLNL_02416 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
IPCOMLNL_02417 9.8e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IPCOMLNL_02418 1.9e-155 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IPCOMLNL_02419 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IPCOMLNL_02420 8.8e-89 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
IPCOMLNL_02421 5.5e-189 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IPCOMLNL_02422 4.2e-181 S Fusaric acid resistance protein-like
IPCOMLNL_02423 1.5e-18
IPCOMLNL_02425 4.4e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IPCOMLNL_02426 7.9e-08 S YyzF-like protein
IPCOMLNL_02428 4.9e-218 yycP
IPCOMLNL_02429 3.7e-134 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IPCOMLNL_02430 3.7e-182 C oxidoreductases (related to aryl-alcohol dehydrogenases)
IPCOMLNL_02431 2.6e-85 yycN 2.3.1.128 K Acetyltransferase
IPCOMLNL_02433 5.4e-198 S Histidine kinase
IPCOMLNL_02434 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
IPCOMLNL_02435 5e-257 rocE E amino acid
IPCOMLNL_02436 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
IPCOMLNL_02437 2.2e-260 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IPCOMLNL_02438 4.5e-145 1.14.11.27 P peptidyl-arginine hydroxylation
IPCOMLNL_02439 3e-306 S ABC transporter
IPCOMLNL_02440 4.5e-195 S Major Facilitator Superfamily
IPCOMLNL_02441 1.8e-261
IPCOMLNL_02442 4.4e-191 2.7.7.73, 2.7.7.80 H ThiF family
IPCOMLNL_02443 2.9e-249 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
IPCOMLNL_02444 2.2e-93 K PFAM response regulator receiver
IPCOMLNL_02445 1.2e-62 S Peptidase propeptide and YPEB domain
IPCOMLNL_02446 6e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPCOMLNL_02447 3.3e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IPCOMLNL_02448 1.9e-150 yycI S protein conserved in bacteria
IPCOMLNL_02449 1.6e-260 yycH S protein conserved in bacteria
IPCOMLNL_02450 0.0 vicK 2.7.13.3 T Histidine kinase
IPCOMLNL_02451 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCOMLNL_02456 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IPCOMLNL_02457 2.9e-72 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPCOMLNL_02458 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IPCOMLNL_02459 6.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
IPCOMLNL_02461 4.6e-17 yycC K YycC-like protein
IPCOMLNL_02462 2.5e-260 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPCOMLNL_02463 3.1e-237 M Glycosyltransferase Family 4
IPCOMLNL_02464 1.8e-203 S Ecdysteroid kinase
IPCOMLNL_02465 2e-235 S Carbamoyl-phosphate synthase L chain, ATP binding domain
IPCOMLNL_02466 1.1e-234 M Glycosyltransferase Family 4
IPCOMLNL_02467 7.8e-120 S GlcNAc-PI de-N-acetylase
IPCOMLNL_02468 4.7e-89 KLT COG0515 Serine threonine protein kinase
IPCOMLNL_02469 4.9e-73 rplI J binds to the 23S rRNA
IPCOMLNL_02470 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IPCOMLNL_02471 3.2e-159 yybS S membrane
IPCOMLNL_02473 1.1e-84 cotF M Spore coat protein
IPCOMLNL_02474 2.8e-66 ydeP3 K Transcriptional regulator
IPCOMLNL_02475 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
IPCOMLNL_02476 5.7e-155 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IPCOMLNL_02477 3.2e-272 sacB 2.4.1.10 GH68 M levansucrase activity
IPCOMLNL_02478 4.9e-309 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
IPCOMLNL_02479 3.4e-115 K FCD domain
IPCOMLNL_02480 1.6e-75 dinB S PFAM DinB family protein
IPCOMLNL_02481 1.2e-161 G Major Facilitator Superfamily
IPCOMLNL_02482 7.3e-84 yijE EG EamA-like transporter family
IPCOMLNL_02483 2.9e-24 K MerR HTH family regulatory protein
IPCOMLNL_02484 3.3e-158 yfiE K LysR substrate binding domain
IPCOMLNL_02485 1.3e-99 E LysE type translocator
IPCOMLNL_02486 1.3e-189 ynfM EGP Major facilitator Superfamily
IPCOMLNL_02487 2.1e-160 gltC K Transcriptional regulator
IPCOMLNL_02488 2.2e-52 ypaA S Protein of unknown function (DUF1304)
IPCOMLNL_02489 9.6e-115 drgA C nitroreductase
IPCOMLNL_02490 4.1e-69 ydgJ K Winged helix DNA-binding domain
IPCOMLNL_02491 3.8e-154 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IPCOMLNL_02492 1e-76 yybA 2.3.1.57 K transcriptional
IPCOMLNL_02493 8.8e-72 yjcF S Acetyltransferase (GNAT) domain
IPCOMLNL_02494 4.9e-162 eaeH M Domain of Unknown Function (DUF1259)
IPCOMLNL_02495 5.4e-41 3.1.3.18 S glycolate biosynthetic process
IPCOMLNL_02496 1.7e-46 mutT 3.6.1.55 F Belongs to the Nudix hydrolase family
IPCOMLNL_02497 3.6e-15 S Psort location Cytoplasmic, score
IPCOMLNL_02498 4.5e-97
IPCOMLNL_02499 3.5e-66 S Leucine-rich repeat (LRR) protein
IPCOMLNL_02500 4.2e-19
IPCOMLNL_02501 4.7e-68 isp O Belongs to the peptidase S8 family
IPCOMLNL_02502 1.6e-250 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPCOMLNL_02503 5.9e-131 ydfC EG EamA-like transporter family
IPCOMLNL_02504 1.1e-122 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IPCOMLNL_02506 5.9e-27 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
IPCOMLNL_02507 3.9e-113 K Bacterial transcription activator, effector binding domain
IPCOMLNL_02508 5.2e-98 S Protein of unknown function (DUF554)
IPCOMLNL_02509 1.2e-21 yyaL O Highly conserved protein containing a thioredoxin domain
IPCOMLNL_02510 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
IPCOMLNL_02511 3.5e-163 yyaK S CAAX protease self-immunity
IPCOMLNL_02512 1.3e-246 ydjK G Sugar (and other) transporter
IPCOMLNL_02513 2.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPCOMLNL_02514 5.2e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
IPCOMLNL_02515 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
IPCOMLNL_02516 2.6e-100 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IPCOMLNL_02517 1.1e-106 adaA 3.2.2.21 K Transcriptional regulator
IPCOMLNL_02518 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPCOMLNL_02519 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IPCOMLNL_02520 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
IPCOMLNL_02521 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IPCOMLNL_02522 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IPCOMLNL_02523 2.3e-33 yyzM S protein conserved in bacteria
IPCOMLNL_02524 4.4e-175 yyaD S Membrane
IPCOMLNL_02525 2.7e-36 4.2.1.103 K FR47-like protein
IPCOMLNL_02526 6.2e-111 yyaC S Sporulation protein YyaC
IPCOMLNL_02527 7.9e-149 spo0J K Belongs to the ParB family
IPCOMLNL_02528 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
IPCOMLNL_02529 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IPCOMLNL_02530 1.6e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IPCOMLNL_02531 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IPCOMLNL_02532 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IPCOMLNL_02533 3.5e-109 jag S single-stranded nucleic acid binding R3H
IPCOMLNL_02534 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IPCOMLNL_02535 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IPCOMLNL_02536 2.3e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IPCOMLNL_02537 3.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IPCOMLNL_02538 2.4e-33 yaaA S S4 domain
IPCOMLNL_02539 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IPCOMLNL_02540 8.1e-38 yaaB S Domain of unknown function (DUF370)
IPCOMLNL_02541 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPCOMLNL_02542 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPCOMLNL_02544 1.3e-07
IPCOMLNL_02547 2e-08
IPCOMLNL_02552 1.3e-29 kdpA 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IPCOMLNL_02555 1.6e-08
IPCOMLNL_02558 1.5e-77 L strictosidine synthase activity
IPCOMLNL_02559 7.5e-45 ant 2.7.7.47 S Domain of unknown function (DUF4111)
IPCOMLNL_02560 1e-28 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPCOMLNL_02561 8.2e-183 Q Non-ribosomal peptide synthetase modules and related proteins
IPCOMLNL_02562 1.4e-99 V ABC transporter transmembrane region
IPCOMLNL_02563 3.3e-51 E Saccharopine dehydrogenase
IPCOMLNL_02564 9.5e-176 S Psort location CytoplasmicMembrane, score
IPCOMLNL_02565 1.6e-49 bacT Q Thioesterase domain
IPCOMLNL_02566 5.6e-226 yvkA EGP Major facilitator Superfamily
IPCOMLNL_02567 7e-110 yvkB K Transcriptional regulator
IPCOMLNL_02568 0.0 yvkC 2.7.9.2 GT Phosphotransferase
IPCOMLNL_02569 7.6e-33 csbA S protein conserved in bacteria
IPCOMLNL_02570 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IPCOMLNL_02571 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IPCOMLNL_02572 2.2e-32 yvkN
IPCOMLNL_02573 6.1e-49 yvlA
IPCOMLNL_02574 4.6e-165 yvlB S Putative adhesin
IPCOMLNL_02575 9.6e-26 pspB KT PspC domain
IPCOMLNL_02576 1.5e-40 yvlD S Membrane
IPCOMLNL_02577 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
IPCOMLNL_02578 3.6e-105 yxaF K Transcriptional regulator
IPCOMLNL_02579 1.5e-132 yvoA K transcriptional
IPCOMLNL_02580 8e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IPCOMLNL_02581 1e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IPCOMLNL_02582 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IPCOMLNL_02583 1.2e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IPCOMLNL_02584 9.1e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IPCOMLNL_02585 3.1e-79 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
IPCOMLNL_02586 1.2e-137 yvpB NU protein conserved in bacteria
IPCOMLNL_02587 2.3e-207 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IPCOMLNL_02588 5.6e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IPCOMLNL_02589 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IPCOMLNL_02590 4.4e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IPCOMLNL_02591 3.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IPCOMLNL_02592 8.4e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IPCOMLNL_02593 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IPCOMLNL_02594 8.1e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
IPCOMLNL_02595 0.0 msbA2 3.6.3.44 V ABC transporter
IPCOMLNL_02596 2.2e-52
IPCOMLNL_02597 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCOMLNL_02598 1.4e-190 sasA T Histidine kinase
IPCOMLNL_02599 5.1e-273 S COG0457 FOG TPR repeat
IPCOMLNL_02600 5e-124 usp CBM50 M protein conserved in bacteria
IPCOMLNL_02601 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IPCOMLNL_02602 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IPCOMLNL_02603 1.1e-166 rapZ S Displays ATPase and GTPase activities
IPCOMLNL_02604 2.2e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IPCOMLNL_02605 3.1e-170 whiA K May be required for sporulation
IPCOMLNL_02606 1.2e-36 crh G Phosphocarrier protein Chr
IPCOMLNL_02607 2.6e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
IPCOMLNL_02608 1.6e-79 M Ribonuclease
IPCOMLNL_02609 1.9e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPCOMLNL_02610 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IPCOMLNL_02611 1.6e-280 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
IPCOMLNL_02612 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
IPCOMLNL_02613 3.4e-103 yvdD 3.2.2.10 S Belongs to the LOG family
IPCOMLNL_02614 1.6e-161 yvdE K Transcriptional regulator
IPCOMLNL_02615 1.1e-309 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
IPCOMLNL_02616 8e-206 mdxE G COG2182 Maltose-binding periplasmic proteins domains
IPCOMLNL_02617 3.1e-221 malC P COG1175 ABC-type sugar transport systems, permease components
IPCOMLNL_02618 2.3e-140 malD P transport
IPCOMLNL_02619 5.8e-102 malA S Protein of unknown function (DUF1189)
IPCOMLNL_02620 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
IPCOMLNL_02621 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
IPCOMLNL_02622 1.5e-97 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
IPCOMLNL_02623 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IPCOMLNL_02624 1.9e-183 scrR K transcriptional
IPCOMLNL_02625 4.7e-219 rafB P LacY proton/sugar symporter
IPCOMLNL_02626 4.4e-296 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
IPCOMLNL_02628 3.1e-34
IPCOMLNL_02629 3.2e-227 I Pfam Lipase (class 3)
IPCOMLNL_02630 4.9e-17 S Protein of unknown function (DUF1433)
IPCOMLNL_02631 1.1e-21 S Protein of unknown function (DUF1433)
IPCOMLNL_02632 7.1e-25 S Protein of unknown function (DUF1433)
IPCOMLNL_02633 2.9e-15 S Protein of unknown function (DUF1433)
IPCOMLNL_02634 6.1e-55 MA20_18690 S Protein of unknown function (DUF3237)
IPCOMLNL_02635 1.6e-93 padC Q Phenolic acid decarboxylase
IPCOMLNL_02636 2.4e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPCOMLNL_02637 1.5e-112 yyaS S Membrane
IPCOMLNL_02638 5.2e-98 ywjB H RibD C-terminal domain
IPCOMLNL_02640 1.8e-281 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
IPCOMLNL_02641 5.1e-78 slr K transcriptional
IPCOMLNL_02642 1.2e-118 ywqC M biosynthesis protein
IPCOMLNL_02643 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
IPCOMLNL_02644 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
IPCOMLNL_02645 2.6e-219 epsD GT4 M Glycosyl transferase 4-like
IPCOMLNL_02646 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IPCOMLNL_02647 4.7e-213 epsF GT4 M Glycosyl transferases group 1
IPCOMLNL_02648 3.5e-205 epsG S EpsG family
IPCOMLNL_02649 3.5e-191 epsH GT2 S Glycosyltransferase like family 2
IPCOMLNL_02650 6e-202 epsI GM pyruvyl transferase
IPCOMLNL_02651 1.2e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
IPCOMLNL_02652 1.6e-272 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPCOMLNL_02653 9.8e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IPCOMLNL_02654 3.5e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
IPCOMLNL_02655 8.2e-221 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
IPCOMLNL_02656 3.3e-183 yvfF GM Exopolysaccharide biosynthesis protein
IPCOMLNL_02657 2.7e-32 yvfG S YvfG protein
IPCOMLNL_02658 4.7e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IPCOMLNL_02659 5e-304 yvfH C L-lactate permease
IPCOMLNL_02660 1.1e-119 yvfI K COG2186 Transcriptional regulators
IPCOMLNL_02661 4.9e-221 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPCOMLNL_02662 9.3e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IPCOMLNL_02663 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IPCOMLNL_02664 6.7e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IPCOMLNL_02665 3.1e-224 gntP EG COG2610 H gluconate symporter and related permeases
IPCOMLNL_02666 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
IPCOMLNL_02667 5.5e-150 ybbH_1 K RpiR family transcriptional regulator
IPCOMLNL_02669 8.5e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
IPCOMLNL_02670 7.2e-156 yvbV EG EamA-like transporter family
IPCOMLNL_02671 4.9e-125 yvbU K Transcriptional regulator
IPCOMLNL_02672 1.7e-187 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCOMLNL_02673 1.3e-204 araR K transcriptional
IPCOMLNL_02674 2.1e-252 araE EGP Major facilitator Superfamily
IPCOMLNL_02676 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IPCOMLNL_02677 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IPCOMLNL_02678 1.9e-217 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IPCOMLNL_02679 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IPCOMLNL_02680 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
IPCOMLNL_02681 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IPCOMLNL_02682 3e-70 yvbK 3.1.3.25 K acetyltransferase
IPCOMLNL_02683 0.0 tcaA S response to antibiotic
IPCOMLNL_02684 8.4e-120 exoY M Membrane
IPCOMLNL_02685 5.2e-105 yvbG U UPF0056 membrane protein
IPCOMLNL_02686 7.1e-98 yvbF K Belongs to the GbsR family
IPCOMLNL_02687 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IPCOMLNL_02688 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IPCOMLNL_02689 1e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IPCOMLNL_02690 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
IPCOMLNL_02691 4.3e-76 yvbF K Belongs to the GbsR family
IPCOMLNL_02692 1.4e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IPCOMLNL_02693 7e-113 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IPCOMLNL_02694 5e-173 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IPCOMLNL_02695 4.7e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
IPCOMLNL_02696 1.8e-125 mutF V ABC transporter, ATP-binding protein
IPCOMLNL_02697 3.5e-121 spaE S ABC-2 family transporter protein
IPCOMLNL_02698 4.2e-133 mutG S ABC-2 family transporter protein
IPCOMLNL_02699 1.4e-121 K Transcriptional regulatory protein, C terminal
IPCOMLNL_02700 7.7e-258 T His Kinase A (phosphoacceptor) domain
IPCOMLNL_02701 4.4e-52 yodB K transcriptional
IPCOMLNL_02702 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
IPCOMLNL_02703 6.7e-69 K transcriptional
IPCOMLNL_02704 6e-35 yvzC K Transcriptional
IPCOMLNL_02705 4.8e-24 secG U Preprotein translocase subunit SecG
IPCOMLNL_02706 2.8e-142 est 3.1.1.1 S Carboxylesterase
IPCOMLNL_02707 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IPCOMLNL_02708 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IPCOMLNL_02710 1.5e-44 yrdF K ribonuclease inhibitor
IPCOMLNL_02711 8.2e-48 yrdF K ribonuclease inhibitor
IPCOMLNL_02712 2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCOMLNL_02713 2.1e-160 ytlI K LysR substrate binding domain
IPCOMLNL_02714 3e-101 ytmI K Acetyltransferase (GNAT) domain
IPCOMLNL_02715 4.2e-131 ytmJ ET Bacterial periplasmic substrate-binding proteins
IPCOMLNL_02716 2.7e-146 tcyK M Bacterial periplasmic substrate-binding proteins
IPCOMLNL_02717 5.9e-121 tcyL P Binding-protein-dependent transport system inner membrane component
IPCOMLNL_02718 4.9e-120 tcyM U Binding-protein-dependent transport system inner membrane component
IPCOMLNL_02719 1.8e-139 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IPCOMLNL_02720 6.4e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCOMLNL_02721 5.6e-46 ytnI O COG0695 Glutaredoxin and related proteins
IPCOMLNL_02722 8.3e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCOMLNL_02723 1.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPCOMLNL_02724 5.2e-195 yvaA 1.1.1.371 S Oxidoreductase
IPCOMLNL_02725 1.4e-47 csoR S transcriptional
IPCOMLNL_02726 2.6e-29 copZ P Heavy-metal-associated domain
IPCOMLNL_02727 0.0 copA 3.6.3.54 P P-type ATPase
IPCOMLNL_02728 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IPCOMLNL_02729 1.2e-102 bdbD O Thioredoxin
IPCOMLNL_02730 5.6e-71 bdbC O Required for disulfide bond formation in some proteins
IPCOMLNL_02731 1.7e-140 S Metallo-peptidase family M12
IPCOMLNL_02732 3.1e-99 yvgT S membrane
IPCOMLNL_02733 0.0 helD 3.6.4.12 L DNA helicase
IPCOMLNL_02734 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IPCOMLNL_02735 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IPCOMLNL_02736 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
IPCOMLNL_02737 1.1e-86 yvgO
IPCOMLNL_02738 5e-156 yvgN S reductase
IPCOMLNL_02739 1.2e-195 yfiN V COG0842 ABC-type multidrug transport system, permease component
IPCOMLNL_02740 2.2e-191 yfiM V ABC-2 type transporter
IPCOMLNL_02741 3.6e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
IPCOMLNL_02742 1.5e-179 T Histidine kinase
IPCOMLNL_02743 5.3e-113 yfiK K Regulator
IPCOMLNL_02744 2.3e-94 modB P COG4149 ABC-type molybdate transport system, permease component
IPCOMLNL_02745 1.2e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
IPCOMLNL_02746 4.5e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
IPCOMLNL_02747 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IPCOMLNL_02748 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
IPCOMLNL_02749 6.1e-14 S Small spore protein J (Spore_SspJ)
IPCOMLNL_02750 4.9e-236 yvsH E Arginine ornithine antiporter
IPCOMLNL_02751 1e-125 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IPCOMLNL_02752 2.6e-177 fhuD P ABC transporter
IPCOMLNL_02753 6.6e-185 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCOMLNL_02754 3.1e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCOMLNL_02755 5.4e-147 fhuC 3.6.3.34 HP ABC transporter
IPCOMLNL_02756 1.4e-66 yvrL S Regulatory protein YrvL
IPCOMLNL_02757 9.2e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
IPCOMLNL_02758 1.2e-15 S YvrJ protein family
IPCOMLNL_02759 7.1e-101 yvrI K RNA polymerase
IPCOMLNL_02760 1.9e-36
IPCOMLNL_02761 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCOMLNL_02762 0.0 T PhoQ Sensor
IPCOMLNL_02763 1.7e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
IPCOMLNL_02764 4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCOMLNL_02765 2.5e-167 yvrC P ABC transporter substrate-binding protein
IPCOMLNL_02766 1.1e-179 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCOMLNL_02767 6.3e-224 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IPCOMLNL_02768 2.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
IPCOMLNL_02769 2.8e-227 yvqJ EGP Major facilitator Superfamily
IPCOMLNL_02770 3.3e-46 liaI S membrane
IPCOMLNL_02771 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IPCOMLNL_02772 1.4e-140 liaG S Putative adhesin
IPCOMLNL_02773 4.3e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
IPCOMLNL_02774 4.3e-192 vraS 2.7.13.3 T Histidine kinase
IPCOMLNL_02775 9.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPCOMLNL_02776 6.4e-207 gerAC S Spore germination B3/ GerAC like, C-terminal
IPCOMLNL_02777 6.6e-188 gerAB E Spore germination protein
IPCOMLNL_02778 2.3e-257 gerAA EG Spore germination protein
IPCOMLNL_02779 6.6e-24 S Protein of unknown function (DUF3970)
IPCOMLNL_02780 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IPCOMLNL_02781 2.4e-156 yuxN K Transcriptional regulator
IPCOMLNL_02782 1.3e-23
IPCOMLNL_02783 2.5e-250 cssS 2.7.13.3 T PhoQ Sensor
IPCOMLNL_02784 2.8e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCOMLNL_02785 8.5e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPCOMLNL_02786 1.6e-79 dps P Belongs to the Dps family
IPCOMLNL_02787 3.2e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCOMLNL_02788 0.0 pepF2 E COG1164 Oligoendopeptidase F
IPCOMLNL_02789 7.9e-44 S YusW-like protein
IPCOMLNL_02790 3.1e-150 yusV 3.6.3.34 HP ABC transporter
IPCOMLNL_02791 3.3e-39 yusU S Protein of unknown function (DUF2573)
IPCOMLNL_02792 3.3e-189 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPCOMLNL_02793 4.7e-137 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
IPCOMLNL_02794 9.7e-158 ywbI2 K Transcriptional regulator
IPCOMLNL_02795 8.1e-288 yusP P Major facilitator superfamily
IPCOMLNL_02796 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
IPCOMLNL_02797 4.2e-53 yusN M Coat F domain
IPCOMLNL_02798 3.9e-43
IPCOMLNL_02799 4e-167 fadM E Proline dehydrogenase
IPCOMLNL_02800 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
IPCOMLNL_02801 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
IPCOMLNL_02802 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
IPCOMLNL_02803 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
IPCOMLNL_02804 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IPCOMLNL_02805 1.1e-39 yusG S Protein of unknown function (DUF2553)
IPCOMLNL_02806 2.2e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
IPCOMLNL_02807 1.6e-54 yusE CO Thioredoxin
IPCOMLNL_02808 5e-57 yusD S SCP-2 sterol transfer family
IPCOMLNL_02809 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IPCOMLNL_02810 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
IPCOMLNL_02811 1.1e-144 metQ P Belongs to the NlpA lipoprotein family
IPCOMLNL_02812 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IPCOMLNL_02813 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IPCOMLNL_02814 1.2e-244 sufD O assembly protein SufD
IPCOMLNL_02815 4.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPCOMLNL_02816 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
IPCOMLNL_02817 3e-270 sufB O FeS cluster assembly
IPCOMLNL_02818 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IPCOMLNL_02819 9.4e-25
IPCOMLNL_02820 7.3e-34
IPCOMLNL_02821 1.5e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
IPCOMLNL_02822 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
IPCOMLNL_02824 2.1e-22 S Sporulation delaying protein SdpA
IPCOMLNL_02825 1.5e-76
IPCOMLNL_02826 8.8e-14
IPCOMLNL_02827 3.3e-164 K helix_turn_helix, mercury resistance
IPCOMLNL_02828 2e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IPCOMLNL_02829 8.9e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
IPCOMLNL_02830 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
IPCOMLNL_02831 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
IPCOMLNL_02832 1.8e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
IPCOMLNL_02833 1.5e-132 yurK K UTRA
IPCOMLNL_02834 1e-204 msmX P Belongs to the ABC transporter superfamily
IPCOMLNL_02835 1.3e-167 bsn L Ribonuclease
IPCOMLNL_02836 2.3e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IPCOMLNL_02837 1.3e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IPCOMLNL_02838 1.4e-212 blt EGP Major facilitator Superfamily
IPCOMLNL_02839 3.4e-70
IPCOMLNL_02840 1.4e-129 S Aspartate phosphatase response regulator
IPCOMLNL_02843 4.1e-300 pucR QT COG2508 Regulator of polyketide synthase expression
IPCOMLNL_02844 4.1e-264 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IPCOMLNL_02845 7.5e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
IPCOMLNL_02846 4.5e-168 yunF S Protein of unknown function DUF72
IPCOMLNL_02847 1.8e-145 yunE S membrane transporter protein
IPCOMLNL_02848 4e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IPCOMLNL_02849 4e-128 yunB S Sporulation protein YunB (Spo_YunB)
IPCOMLNL_02850 1.1e-194 lytH M Peptidase, M23
IPCOMLNL_02851 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IPCOMLNL_02852 1.7e-47 yutD S protein conserved in bacteria
IPCOMLNL_02853 1.4e-72 yutE S Protein of unknown function DUF86
IPCOMLNL_02854 4.7e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IPCOMLNL_02855 7.9e-87 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
IPCOMLNL_02856 1.2e-196 yutH S Spore coat protein
IPCOMLNL_02857 1e-240 hom 1.1.1.3 E homoserine dehydrogenase
IPCOMLNL_02858 2.2e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IPCOMLNL_02859 2.6e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IPCOMLNL_02860 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
IPCOMLNL_02861 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
IPCOMLNL_02862 1.7e-54 yuzD S protein conserved in bacteria
IPCOMLNL_02863 4.2e-208 yutJ 1.6.99.3 C NADH dehydrogenase
IPCOMLNL_02864 2.4e-39 yuzB S Belongs to the UPF0349 family
IPCOMLNL_02865 1.9e-212 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IPCOMLNL_02866 1.6e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IPCOMLNL_02867 1.1e-62 erpA S Belongs to the HesB IscA family
IPCOMLNL_02868 4e-136 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCOMLNL_02869 2.1e-94 rimJ 2.3.1.128 J Alanine acetyltransferase
IPCOMLNL_02871 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
IPCOMLNL_02873 8.9e-122 V ABC transporter
IPCOMLNL_02874 2e-70 CP Membrane
IPCOMLNL_02875 4.8e-29
IPCOMLNL_02876 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IPCOMLNL_02878 1.5e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
IPCOMLNL_02879 7.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
IPCOMLNL_02880 9.9e-28 yuiB S Putative membrane protein
IPCOMLNL_02881 6e-117 yuiC S protein conserved in bacteria
IPCOMLNL_02882 1.2e-77 yuiD S protein conserved in bacteria
IPCOMLNL_02883 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IPCOMLNL_02884 2.4e-208 yuiF S antiporter
IPCOMLNL_02885 1.1e-101 bioY S Biotin biosynthesis protein
IPCOMLNL_02886 4.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
IPCOMLNL_02887 3.6e-165 besA S Putative esterase
IPCOMLNL_02888 1e-134 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCOMLNL_02889 5.8e-222 entC 5.4.4.2 HQ Isochorismate synthase
IPCOMLNL_02890 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
IPCOMLNL_02891 6.5e-173 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
IPCOMLNL_02892 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_02893 1.3e-34 mbtH S MbtH-like protein
IPCOMLNL_02894 7.5e-134 yukJ S Uncharacterized conserved protein (DUF2278)
IPCOMLNL_02895 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
IPCOMLNL_02896 3.2e-228 yukF QT Transcriptional regulator
IPCOMLNL_02897 3.3e-46 esxA S Belongs to the WXG100 family
IPCOMLNL_02898 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
IPCOMLNL_02899 3.7e-206 essB S WXG100 protein secretion system (Wss), protein YukC
IPCOMLNL_02900 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IPCOMLNL_02901 0.0 esaA S type VII secretion protein EsaA
IPCOMLNL_02902 2.2e-76 yueC S Family of unknown function (DUF5383)
IPCOMLNL_02903 4.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCOMLNL_02904 3.7e-96 yueE S phosphohydrolase
IPCOMLNL_02905 2.1e-22 S Protein of unknown function (DUF2642)
IPCOMLNL_02906 5.6e-187 yueF S transporter activity
IPCOMLNL_02907 6.4e-34 yueG S Spore germination protein gerPA/gerPF
IPCOMLNL_02908 2.8e-38 yueH S YueH-like protein
IPCOMLNL_02909 6.1e-67 yueI S Protein of unknown function (DUF1694)
IPCOMLNL_02910 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
IPCOMLNL_02911 2.5e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IPCOMLNL_02912 1.7e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
IPCOMLNL_02913 1.2e-52 yuzC
IPCOMLNL_02915 8.9e-98 comQ H Belongs to the FPP GGPP synthase family
IPCOMLNL_02917 1.3e-275 comP 2.7.13.3 T Histidine kinase
IPCOMLNL_02918 3.4e-112 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPCOMLNL_02919 1.6e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
IPCOMLNL_02920 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
IPCOMLNL_02921 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPCOMLNL_02922 1.3e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPCOMLNL_02923 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPCOMLNL_02924 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPCOMLNL_02925 9.2e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPCOMLNL_02926 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IPCOMLNL_02927 1.8e-12
IPCOMLNL_02928 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
IPCOMLNL_02929 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
IPCOMLNL_02930 4.7e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IPCOMLNL_02931 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
IPCOMLNL_02932 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
IPCOMLNL_02933 1.7e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IPCOMLNL_02934 9.3e-74 yufK S Family of unknown function (DUF5366)
IPCOMLNL_02935 4.2e-71 yuxK S protein conserved in bacteria
IPCOMLNL_02936 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
IPCOMLNL_02937 4.5e-185 yuxJ EGP Major facilitator Superfamily
IPCOMLNL_02938 1.3e-117 kapD L the KinA pathway to sporulation
IPCOMLNL_02939 2.6e-67 kapB G Kinase associated protein B
IPCOMLNL_02940 8.1e-230 T PhoQ Sensor
IPCOMLNL_02941 1.2e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IPCOMLNL_02942 2.7e-39 yugE S Domain of unknown function (DUF1871)
IPCOMLNL_02943 1.4e-155 yugF I Hydrolase
IPCOMLNL_02944 2e-83 alaR K Transcriptional regulator
IPCOMLNL_02945 5e-210 yugH 2.6.1.1 E Aminotransferase
IPCOMLNL_02946 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
IPCOMLNL_02947 1.8e-34 yuzA S Domain of unknown function (DUF378)
IPCOMLNL_02948 4.2e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
IPCOMLNL_02949 7.4e-230 yugK C Dehydrogenase
IPCOMLNL_02950 4.2e-118 ycaC Q Isochorismatase family
IPCOMLNL_02951 5.7e-95 S NADPH-dependent FMN reductase
IPCOMLNL_02952 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
IPCOMLNL_02954 4.9e-72 yugN S YugN-like family
IPCOMLNL_02955 2.6e-180 yugO P COG1226 Kef-type K transport systems
IPCOMLNL_02956 5.1e-27 mstX S Membrane-integrating protein Mistic
IPCOMLNL_02957 1.3e-17
IPCOMLNL_02958 9.2e-116 yugP S Zn-dependent protease
IPCOMLNL_02959 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
IPCOMLNL_02960 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
IPCOMLNL_02961 3.1e-77 yugU S Uncharacterised protein family UPF0047
IPCOMLNL_02962 6.6e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IPCOMLNL_02963 1.8e-40
IPCOMLNL_02964 1.3e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
IPCOMLNL_02965 1.8e-220 mcpA NT chemotaxis protein
IPCOMLNL_02966 6.8e-236 mcpA NT chemotaxis protein
IPCOMLNL_02967 5.1e-223 mcpA NT chemotaxis protein
IPCOMLNL_02968 6.2e-237 mcpA NT chemotaxis protein
IPCOMLNL_02969 1.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
IPCOMLNL_02970 6.1e-185 ygjR S Oxidoreductase
IPCOMLNL_02971 1.7e-194 yubA S transporter activity
IPCOMLNL_02972 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IPCOMLNL_02974 3.7e-51 yjcN
IPCOMLNL_02975 1.8e-121 G Cupin
IPCOMLNL_02976 6.5e-218 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IPCOMLNL_02977 4e-145 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IPCOMLNL_02978 5.5e-121 ktrA P COG0569 K transport systems, NAD-binding component
IPCOMLNL_02979 1.1e-92 yuaB
IPCOMLNL_02980 1.5e-95 yuaC K Belongs to the GbsR family
IPCOMLNL_02981 5.5e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
IPCOMLNL_02982 1.6e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
IPCOMLNL_02983 2.7e-108 yuaD S MOSC domain
IPCOMLNL_02984 7.6e-80 yuaE S DinB superfamily
IPCOMLNL_02985 5.6e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
IPCOMLNL_02986 5.9e-179 yuaG 3.4.21.72 S protein conserved in bacteria
IPCOMLNL_02987 9.7e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
IPCOMLNL_02988 5.5e-15 NT Two component signalling adaptor domain
IPCOMLNL_02989 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IPCOMLNL_02990 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
IPCOMLNL_02991 1e-154 yloC S stress-induced protein
IPCOMLNL_02992 1.5e-40 ylzA S Belongs to the UPF0296 family
IPCOMLNL_02993 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IPCOMLNL_02994 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IPCOMLNL_02995 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IPCOMLNL_02996 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IPCOMLNL_02997 3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IPCOMLNL_02998 4.3e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IPCOMLNL_02999 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IPCOMLNL_03000 2.6e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IPCOMLNL_03001 1.7e-139 stp 3.1.3.16 T phosphatase
IPCOMLNL_03002 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IPCOMLNL_03003 8.2e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IPCOMLNL_03004 2.3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IPCOMLNL_03005 2e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
IPCOMLNL_03006 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IPCOMLNL_03007 5.5e-59 asp S protein conserved in bacteria
IPCOMLNL_03008 6.4e-304 yloV S kinase related to dihydroxyacetone kinase
IPCOMLNL_03009 8.1e-117 sdaAB 4.3.1.17 E L-serine dehydratase
IPCOMLNL_03010 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
IPCOMLNL_03011 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IPCOMLNL_03012 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IPCOMLNL_03013 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IPCOMLNL_03014 7e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IPCOMLNL_03015 4.6e-129 IQ reductase
IPCOMLNL_03016 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPCOMLNL_03017 4.4e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IPCOMLNL_03018 0.0 smc D Required for chromosome condensation and partitioning
IPCOMLNL_03019 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IPCOMLNL_03020 3.9e-139 S Phosphotransferase enzyme family
IPCOMLNL_03021 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IPCOMLNL_03022 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IPCOMLNL_03023 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IPCOMLNL_03024 1.7e-35 ylqC S Belongs to the UPF0109 family
IPCOMLNL_03025 1.3e-61 ylqD S YlqD protein
IPCOMLNL_03026 1.3e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IPCOMLNL_03027 5.4e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IPCOMLNL_03028 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IPCOMLNL_03029 6.4e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IPCOMLNL_03030 7.7e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPCOMLNL_03031 1.8e-301 ylqG
IPCOMLNL_03032 6.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
IPCOMLNL_03033 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IPCOMLNL_03034 2.3e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IPCOMLNL_03035 2.1e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
IPCOMLNL_03036 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IPCOMLNL_03037 2.2e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IPCOMLNL_03038 7.2e-172 xerC L tyrosine recombinase XerC
IPCOMLNL_03039 2e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IPCOMLNL_03040 4.5e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IPCOMLNL_03041 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IPCOMLNL_03042 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IPCOMLNL_03043 2.4e-75 flgC N Belongs to the flagella basal body rod proteins family
IPCOMLNL_03044 5.6e-31 fliE N Flagellar hook-basal body
IPCOMLNL_03045 2.4e-263 fliF N The M ring may be actively involved in energy transduction
IPCOMLNL_03046 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IPCOMLNL_03047 4.3e-90 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
IPCOMLNL_03048 5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IPCOMLNL_03049 4.5e-71 fliJ N Flagellar biosynthesis chaperone
IPCOMLNL_03050 1.3e-47 ylxF S MgtE intracellular N domain
IPCOMLNL_03051 2.1e-204 fliK N Flagellar hook-length control protein
IPCOMLNL_03052 5.3e-72 flgD N Flagellar basal body rod modification protein
IPCOMLNL_03053 4e-139 flgG N Flagellar basal body rod
IPCOMLNL_03054 2.3e-56 fliL N Controls the rotational direction of flagella during chemotaxis
IPCOMLNL_03055 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IPCOMLNL_03056 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IPCOMLNL_03057 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
IPCOMLNL_03058 5e-111 fliZ N Flagellar biosynthesis protein, FliO
IPCOMLNL_03059 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
IPCOMLNL_03060 2e-37 fliQ N Role in flagellar biosynthesis
IPCOMLNL_03061 7.5e-130 fliR N Flagellar biosynthetic protein FliR
IPCOMLNL_03062 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IPCOMLNL_03063 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IPCOMLNL_03064 2.6e-192 flhF N Flagellar biosynthesis regulator FlhF
IPCOMLNL_03065 1e-154 flhG D Belongs to the ParA family
IPCOMLNL_03066 1.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IPCOMLNL_03067 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
IPCOMLNL_03068 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
IPCOMLNL_03069 3.7e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IPCOMLNL_03070 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IPCOMLNL_03071 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCOMLNL_03072 5.3e-54 ylxL
IPCOMLNL_03073 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
IPCOMLNL_03074 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IPCOMLNL_03075 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IPCOMLNL_03076 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IPCOMLNL_03077 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPCOMLNL_03078 3.4e-138 cdsA 2.7.7.41 S Belongs to the CDS family
IPCOMLNL_03079 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IPCOMLNL_03080 5.9e-233 rasP M zinc metalloprotease
IPCOMLNL_03081 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IPCOMLNL_03082 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPCOMLNL_03083 8.7e-81 rimP S Required for maturation of 30S ribosomal subunits
IPCOMLNL_03084 5.4e-206 nusA K Participates in both transcription termination and antitermination
IPCOMLNL_03085 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
IPCOMLNL_03086 1.8e-47 ylxQ J ribosomal protein
IPCOMLNL_03087 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IPCOMLNL_03088 3.9e-44 ylxP S protein conserved in bacteria
IPCOMLNL_03089 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IPCOMLNL_03090 1.9e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IPCOMLNL_03091 2.3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IPCOMLNL_03092 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IPCOMLNL_03093 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IPCOMLNL_03094 1.8e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
IPCOMLNL_03095 1.5e-233 pepR S Belongs to the peptidase M16 family
IPCOMLNL_03096 2.6e-42 ymxH S YlmC YmxH family
IPCOMLNL_03097 3.6e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
IPCOMLNL_03098 5.7e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IPCOMLNL_03099 1.9e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IPCOMLNL_03100 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IPCOMLNL_03101 3.1e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPCOMLNL_03102 4.4e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPCOMLNL_03103 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
IPCOMLNL_03104 6.3e-31 S YlzJ-like protein
IPCOMLNL_03105 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IPCOMLNL_03106 1.8e-133 ymfC K Transcriptional regulator
IPCOMLNL_03107 4.1e-229 ymfD EGP Major facilitator Superfamily
IPCOMLNL_03108 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
IPCOMLNL_03109 0.0 ydgH S drug exporters of the RND superfamily
IPCOMLNL_03110 1.2e-238 ymfF S Peptidase M16
IPCOMLNL_03111 3.4e-244 ymfH S zinc protease
IPCOMLNL_03112 3e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IPCOMLNL_03113 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
IPCOMLNL_03114 1e-142 ymfK S Protein of unknown function (DUF3388)
IPCOMLNL_03115 4.2e-124 ymfM S protein conserved in bacteria
IPCOMLNL_03116 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IPCOMLNL_03117 4.2e-231 cinA 3.5.1.42 S Belongs to the CinA family
IPCOMLNL_03118 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IPCOMLNL_03119 9.2e-180 pbpX V Beta-lactamase
IPCOMLNL_03120 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
IPCOMLNL_03121 4.9e-153 ymdB S protein conserved in bacteria
IPCOMLNL_03122 1.2e-36 spoVS S Stage V sporulation protein S
IPCOMLNL_03123 3.6e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IPCOMLNL_03124 3.9e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IPCOMLNL_03125 4.2e-294 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IPCOMLNL_03126 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IPCOMLNL_03127 1.7e-88 cotE S Spore coat protein
IPCOMLNL_03128 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IPCOMLNL_03129 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IPCOMLNL_03130 2.7e-65 L Phage integrase family
IPCOMLNL_03133 2.9e-38 S HNH endonuclease
IPCOMLNL_03134 7.7e-40
IPCOMLNL_03135 1.7e-174 A Pre-toxin TG
IPCOMLNL_03137 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
IPCOMLNL_03138 9.8e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IPCOMLNL_03139 3.3e-183 pksD Q Acyl transferase domain
IPCOMLNL_03140 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IPCOMLNL_03141 1.9e-34 acpK IQ Phosphopantetheine attachment site
IPCOMLNL_03142 3.7e-243 pksG 2.3.3.10 I synthase
IPCOMLNL_03143 8.5e-142 pksH 4.2.1.18 I enoyl-CoA hydratase
IPCOMLNL_03144 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
IPCOMLNL_03145 0.0 rhiB IQ polyketide synthase
IPCOMLNL_03146 0.0 Q Polyketide synthase of type I
IPCOMLNL_03147 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
IPCOMLNL_03148 0.0 dhbF IQ polyketide synthase
IPCOMLNL_03149 0.0 pks13 HQ Beta-ketoacyl synthase
IPCOMLNL_03150 1e-229 cypA C Cytochrome P450
IPCOMLNL_03151 4.9e-78 nucB M Deoxyribonuclease NucA/NucB
IPCOMLNL_03152 5.1e-117 yoaK S Membrane
IPCOMLNL_03153 1.4e-62 ymzB
IPCOMLNL_03154 6.8e-256 aprX O Belongs to the peptidase S8 family
IPCOMLNL_03156 7.8e-126 ymaC S Replication protein
IPCOMLNL_03157 6e-79 ymaD O redox protein, regulator of disulfide bond formation
IPCOMLNL_03158 1.2e-53 ebrB P Small Multidrug Resistance protein
IPCOMLNL_03159 3.1e-48 ebrA P Small Multidrug Resistance protein
IPCOMLNL_03161 1.4e-47 ymaF S YmaF family
IPCOMLNL_03162 2.5e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IPCOMLNL_03163 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IPCOMLNL_03164 9.4e-43
IPCOMLNL_03165 1.8e-20 ymzA
IPCOMLNL_03166 1.7e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
IPCOMLNL_03167 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPCOMLNL_03168 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPCOMLNL_03169 5.6e-25 ymaB S MutT family
IPCOMLNL_03170 2.5e-50 ymaB S MutT family
IPCOMLNL_03171 3.1e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IPCOMLNL_03172 1.6e-96 spoVK O stage V sporulation protein K
IPCOMLNL_03173 5.8e-79 yokF 3.1.31.1 L RNA catabolic process
IPCOMLNL_03174 6.3e-246 UW nuclease activity
IPCOMLNL_03175 5.1e-84 yokJ S SMI1 / KNR4 family (SUKH-1)
IPCOMLNL_03176 2.9e-61 S Protein of unknown function, DUF600
IPCOMLNL_03177 1.5e-58 yokK S SMI1 / KNR4 family
IPCOMLNL_03179 7.7e-127 yunB S Sporulation protein YunB (Spo_YunB)
IPCOMLNL_03180 1.6e-41 S YolD-like protein
IPCOMLNL_03181 4.6e-222 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPCOMLNL_03183 3.1e-87 S response regulator aspartate phosphatase
IPCOMLNL_03186 3.1e-32 S Bacteriophage holin
IPCOMLNL_03188 5.3e-78 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IPCOMLNL_03189 2.2e-279 M Pectate lyase superfamily protein
IPCOMLNL_03190 4.2e-91
IPCOMLNL_03192 0.0 S Pfam Transposase IS66
IPCOMLNL_03193 2.9e-126 S Phage tail protein
IPCOMLNL_03194 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IPCOMLNL_03195 2.1e-75
IPCOMLNL_03197 1.2e-111 xerH L Belongs to the 'phage' integrase family
IPCOMLNL_03198 1.3e-48
IPCOMLNL_03199 5.5e-54
IPCOMLNL_03200 6e-81 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
IPCOMLNL_03201 1.6e-13
IPCOMLNL_03202 5.7e-53 S Domain of unknown function (DUF2479)
IPCOMLNL_03203 8.8e-49
IPCOMLNL_03205 7.1e-91
IPCOMLNL_03206 2.6e-89
IPCOMLNL_03207 1.3e-85
IPCOMLNL_03208 4.7e-95
IPCOMLNL_03210 3.3e-65
IPCOMLNL_03211 3.7e-79
IPCOMLNL_03212 2e-183
IPCOMLNL_03213 2.1e-91
IPCOMLNL_03214 8.5e-220
IPCOMLNL_03215 6e-256
IPCOMLNL_03216 0.0 gp17a S Terminase-like family
IPCOMLNL_03217 1.4e-170
IPCOMLNL_03221 1.1e-218 S Calcineurin-like phosphoesterase superfamily domain
IPCOMLNL_03223 2.7e-34 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IPCOMLNL_03224 0.0
IPCOMLNL_03228 4.5e-59 ftsZ D Tubulin/FtsZ family, GTPase domain
IPCOMLNL_03231 5.3e-154
IPCOMLNL_03232 1.2e-33 S DNA binding
IPCOMLNL_03233 1.7e-34
IPCOMLNL_03237 3.4e-17
IPCOMLNL_03239 3.3e-22 I Acyltransferase family
IPCOMLNL_03240 1.4e-69 yoaW
IPCOMLNL_03243 1.6e-08 K Cro/C1-type HTH DNA-binding domain
IPCOMLNL_03247 3.3e-43
IPCOMLNL_03250 7.7e-25
IPCOMLNL_03254 3.8e-50 smuG L deaminated base DNA N-glycosylase activity
IPCOMLNL_03255 3.5e-80
IPCOMLNL_03257 9.4e-39 S HicB_like antitoxin of bacterial toxin-antitoxin system
IPCOMLNL_03258 1.6e-80
IPCOMLNL_03264 1.2e-37 L Belongs to the 'phage' integrase family
IPCOMLNL_03265 2.8e-188
IPCOMLNL_03266 9.8e-34
IPCOMLNL_03267 1.5e-11 K Transcriptional regulator
IPCOMLNL_03275 1.8e-09 FG Mazg nucleotide pyrophosphohydrolase
IPCOMLNL_03278 3.3e-73 U Protein of unknown function DUF262
IPCOMLNL_03282 2.4e-23
IPCOMLNL_03289 8.8e-74
IPCOMLNL_03291 1e-50 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
IPCOMLNL_03294 7.8e-138 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
IPCOMLNL_03295 1.1e-124 yoqW S Belongs to the SOS response-associated peptidase family
IPCOMLNL_03297 4e-14 S YopX protein
IPCOMLNL_03299 7.8e-93 S Pfam:DUF867
IPCOMLNL_03300 2.1e-220 M Parallel beta-helix repeats
IPCOMLNL_03305 5.6e-56 nrnB S phosphohydrolase (DHH superfamily)
IPCOMLNL_03306 9.1e-170
IPCOMLNL_03307 5.5e-158 S AAA domain
IPCOMLNL_03309 1.4e-241 3.6.4.12 L DnaB-like helicase C terminal domain
IPCOMLNL_03310 1.2e-146 3.6.4.12 L DNA primase activity
IPCOMLNL_03311 1.4e-171 S PD-(D/E)XK nuclease superfamily
IPCOMLNL_03312 1.3e-291 polB 2.7.7.7 L DNA polymerase elongation subunit (Family B)
IPCOMLNL_03313 1.5e-23 DR0488 S protein conserved in bacteria
IPCOMLNL_03316 8.1e-69 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
IPCOMLNL_03317 2.6e-86 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
IPCOMLNL_03322 7.6e-10
IPCOMLNL_03338 4.8e-56 S NrdI Flavodoxin like
IPCOMLNL_03339 0.0 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
IPCOMLNL_03341 3.6e-103 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPCOMLNL_03343 1.4e-67 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPCOMLNL_03344 1.5e-28 O Glutaredoxin
IPCOMLNL_03345 5.1e-72 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
IPCOMLNL_03349 3.2e-09 S Protein of unknown function (DUF1643)
IPCOMLNL_03350 7.4e-131 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IPCOMLNL_03351 2.9e-29 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IPCOMLNL_03358 3.6e-19 V regulation of methylation-dependent chromatin silencing
IPCOMLNL_03359 3.7e-151 S Calcineurin-like phosphoesterase
IPCOMLNL_03362 6.5e-08
IPCOMLNL_03368 5.7e-93 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IPCOMLNL_03370 1.6e-246 cisA2 L Recombinase
IPCOMLNL_03371 1.3e-69 spoVK O stage V sporulation protein K
IPCOMLNL_03372 3.2e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IPCOMLNL_03373 1.8e-242 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IPCOMLNL_03374 1.6e-67 glnR K transcriptional
IPCOMLNL_03375 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
IPCOMLNL_03376 3.1e-31 S nuclease activity
IPCOMLNL_03379 3.2e-21
IPCOMLNL_03381 8.1e-207 mrjp G Major royal jelly protein
IPCOMLNL_03382 1.4e-251 xynT G MFS/sugar transport protein
IPCOMLNL_03383 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
IPCOMLNL_03384 7.6e-211 xylR GK ROK family
IPCOMLNL_03385 1.3e-259 xylA 5.3.1.5 G Belongs to the xylose isomerase family
IPCOMLNL_03387 3.8e-287 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
IPCOMLNL_03388 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
IPCOMLNL_03391 5.4e-17
IPCOMLNL_03392 2.4e-119 K WYL domain
IPCOMLNL_03393 9.9e-67 S DinB family
IPCOMLNL_03394 5.7e-186 adhP 1.1.1.1 C alcohol dehydrogenase
IPCOMLNL_03397 1.9e-16
IPCOMLNL_03398 2.9e-20 yoaW
IPCOMLNL_03400 2.6e-143 yoaP 3.1.3.18 K YoaP-like
IPCOMLNL_03401 9.1e-32 yqiB S Protein of unknown function (DUF1249)
IPCOMLNL_03402 9.3e-21
IPCOMLNL_03403 6.5e-16 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
IPCOMLNL_03404 8.2e-165 ygxA S Nucleotidyltransferase-like
IPCOMLNL_03405 1.5e-56 ygzB S UPF0295 protein
IPCOMLNL_03406 1.8e-80 perR P Belongs to the Fur family
IPCOMLNL_03407 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
IPCOMLNL_03408 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IPCOMLNL_03409 3.2e-179 ygaE S Membrane
IPCOMLNL_03410 4.2e-306 ygaD V ABC transporter
IPCOMLNL_03411 2.2e-104 ygaC J Belongs to the UPF0374 family
IPCOMLNL_03412 1.5e-37 ygaB S YgaB-like protein
IPCOMLNL_03414 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCOMLNL_03415 1.8e-36 yfhS
IPCOMLNL_03416 8.8e-209 mutY L A G-specific
IPCOMLNL_03417 1.5e-183 yfhP S membrane-bound metal-dependent
IPCOMLNL_03418 0.0 yfhO S Bacterial membrane protein YfhO
IPCOMLNL_03419 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IPCOMLNL_03420 3.5e-168 yfhM S Alpha/beta hydrolase family
IPCOMLNL_03421 3.3e-34 yfhL S SdpI/YhfL protein family
IPCOMLNL_03422 1.6e-94 batE T Bacterial SH3 domain homologues
IPCOMLNL_03423 4.9e-44 yfhJ S WVELL protein
IPCOMLNL_03424 1.4e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
IPCOMLNL_03426 1.7e-205 yfhI EGP Major facilitator Superfamily
IPCOMLNL_03427 8.8e-53 yfhH S Protein of unknown function (DUF1811)
IPCOMLNL_03428 1.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
IPCOMLNL_03429 2e-166 yfhF S nucleoside-diphosphate sugar epimerase
IPCOMLNL_03431 2.1e-25 yfhD S YfhD-like protein
IPCOMLNL_03432 3.3e-106 yfhC C nitroreductase
IPCOMLNL_03433 2.6e-163 yfhB 5.3.3.17 S PhzF family
IPCOMLNL_03434 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IPCOMLNL_03435 9.5e-83 yfiV K transcriptional
IPCOMLNL_03436 1.4e-287 yfiU EGP Major facilitator Superfamily
IPCOMLNL_03437 1.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
IPCOMLNL_03438 1.5e-45 yrdF K ribonuclease inhibitor
IPCOMLNL_03439 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
IPCOMLNL_03440 7.2e-179 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IPCOMLNL_03441 1.1e-112 1.6.5.2 S NADPH-dependent FMN reductase
IPCOMLNL_03442 8.6e-96 padR K transcriptional
IPCOMLNL_03443 8.5e-168 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IPCOMLNL_03444 1e-159 yfiE 1.13.11.2 S glyoxalase
IPCOMLNL_03445 2.4e-63 mhqP S DoxX
IPCOMLNL_03446 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
IPCOMLNL_03447 2.4e-311 yfiB3 V ABC transporter
IPCOMLNL_03448 0.0 M Peptidase_G2, IMC autoproteolytic cleavage domain
IPCOMLNL_03449 4e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IPCOMLNL_03450 1.5e-138 glvR F Helix-turn-helix domain, rpiR family
IPCOMLNL_03451 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IPCOMLNL_03452 4.2e-15 sspH S Belongs to the SspH family
IPCOMLNL_03453 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
IPCOMLNL_03454 6e-255 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IPCOMLNL_03455 4.1e-212 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IPCOMLNL_03456 2.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IPCOMLNL_03457 6.4e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IPCOMLNL_03458 1.4e-89 yfjM S Psort location Cytoplasmic, score
IPCOMLNL_03459 7.9e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPCOMLNL_03460 5.1e-50 S YfzA-like protein
IPCOMLNL_03461 7.4e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPCOMLNL_03462 2.4e-161 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IPCOMLNL_03463 3.8e-184 corA P Mediates influx of magnesium ions
IPCOMLNL_03464 1e-31
IPCOMLNL_03465 3.4e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IPCOMLNL_03466 9e-155 pdaA G deacetylase
IPCOMLNL_03467 4.9e-27 yfjT
IPCOMLNL_03468 4.3e-219 yfkA S YfkB-like domain
IPCOMLNL_03469 3.6e-146 yfkC M Mechanosensitive ion channel
IPCOMLNL_03470 1.6e-143 yfkD S YfkD-like protein
IPCOMLNL_03471 2.5e-184 cax P COG0387 Ca2 H antiporter
IPCOMLNL_03472 6.5e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
IPCOMLNL_03474 6.8e-145 yihY S Belongs to the UPF0761 family
IPCOMLNL_03475 5e-51 yfkI S gas vesicle protein
IPCOMLNL_03476 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPCOMLNL_03477 2.7e-29 yfkK S Belongs to the UPF0435 family
IPCOMLNL_03478 4.3e-193 ydiM EGP Major facilitator Superfamily
IPCOMLNL_03479 9.9e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IPCOMLNL_03480 1.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPCOMLNL_03481 2.6e-186 K helix_turn _helix lactose operon repressor
IPCOMLNL_03482 1.7e-90 yfkM 1.11.1.6, 3.5.1.124 S protease
IPCOMLNL_03483 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
IPCOMLNL_03484 3.8e-199 yibE S YibE/F-like protein
IPCOMLNL_03485 1e-123 yibF S YibE/F-like protein
IPCOMLNL_03486 2e-123 yfkO C nitroreductase
IPCOMLNL_03487 4.5e-129 treR K transcriptional
IPCOMLNL_03488 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IPCOMLNL_03489 1.5e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IPCOMLNL_03490 1.5e-37 ydgB S Spore germination protein gerPA/gerPF
IPCOMLNL_03491 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
IPCOMLNL_03492 9.8e-79 cotP O Belongs to the small heat shock protein (HSP20) family
IPCOMLNL_03493 7.8e-64 yhdN S Domain of unknown function (DUF1992)
IPCOMLNL_03494 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IPCOMLNL_03495 1.8e-72 yfmQ S Uncharacterised protein from bacillus cereus group
IPCOMLNL_03496 1.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IPCOMLNL_03497 2.7e-137 map 3.4.11.18 E Methionine aminopeptidase
IPCOMLNL_03498 3.1e-50 yflH S Protein of unknown function (DUF3243)
IPCOMLNL_03499 7e-19 yflI
IPCOMLNL_03500 1.5e-14 yflJ S Protein of unknown function (DUF2639)
IPCOMLNL_03501 2.9e-118 yflK S protein conserved in bacteria
IPCOMLNL_03502 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IPCOMLNL_03503 7.1e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IPCOMLNL_03504 3.3e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
IPCOMLNL_03505 2.5e-226 citM C Citrate transporter
IPCOMLNL_03506 8.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
IPCOMLNL_03507 1.8e-119 citT T response regulator
IPCOMLNL_03508 2.5e-268 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IPCOMLNL_03509 4.6e-80 srtA 3.4.22.70 M Sortase family
IPCOMLNL_03510 0.0 M1-568 M cell wall anchor domain
IPCOMLNL_03511 7.4e-152 M1-574 T Transcriptional regulatory protein, C terminal
IPCOMLNL_03512 0.0 ywpD T PhoQ Sensor
IPCOMLNL_03513 9.3e-78 M1-820 Q Collagen triple helix repeat (20 copies)
IPCOMLNL_03514 9.2e-15 Q calcium- and calmodulin-responsive adenylate cyclase activity
IPCOMLNL_03516 4.6e-28 Q PFAM Collagen triple helix
IPCOMLNL_03517 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
IPCOMLNL_03518 5e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
IPCOMLNL_03519 1.3e-57 yflT S Heat induced stress protein YflT
IPCOMLNL_03520 1.2e-24 S Protein of unknown function (DUF3212)
IPCOMLNL_03521 5.5e-189 yfmJ S N-terminal domain of oxidoreductase
IPCOMLNL_03522 1.4e-41 yfmK 2.3.1.128 K acetyltransferase
IPCOMLNL_03523 1.1e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
IPCOMLNL_03524 4.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IPCOMLNL_03525 2.1e-208 yfmO EGP Major facilitator Superfamily
IPCOMLNL_03526 1.8e-69 yfmP K transcriptional
IPCOMLNL_03527 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IPCOMLNL_03528 3.2e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IPCOMLNL_03529 2.6e-166 IQ Enoyl-(Acyl carrier protein) reductase
IPCOMLNL_03530 2.2e-106 yfmS NT chemotaxis protein
IPCOMLNL_03531 2.6e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IPCOMLNL_03532 2.3e-246 yfnA E amino acid
IPCOMLNL_03533 2.3e-218 fsr P COG0477 Permeases of the major facilitator superfamily
IPCOMLNL_03534 2.4e-186 yfnD M Nucleotide-diphospho-sugar transferase
IPCOMLNL_03535 2.5e-222 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
IPCOMLNL_03536 9.3e-180 yfnF M Nucleotide-diphospho-sugar transferase
IPCOMLNL_03537 2.4e-172 yfnG 4.2.1.45 M dehydratase
IPCOMLNL_03538 3.3e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
IPCOMLNL_03539 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IPCOMLNL_03540 3e-145 2.1.1.163, 2.1.1.201 Q methyltransferase
IPCOMLNL_03541 2.8e-112 S CAAX protease self-immunity
IPCOMLNL_03542 1.7e-153 sagB C Nitroreductase family
IPCOMLNL_03543 9.9e-263 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
IPCOMLNL_03544 1.3e-182 S ATP diphosphatase activity
IPCOMLNL_03545 6.6e-125
IPCOMLNL_03546 8.1e-70 S protein homooligomerization
IPCOMLNL_03547 8.2e-126 V ABC-2 type transporter
IPCOMLNL_03548 4.5e-163 V ATPases associated with a variety of cellular activities
IPCOMLNL_03549 5.8e-49 MA20_23570 K Winged helix DNA-binding domain
IPCOMLNL_03551 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IPCOMLNL_03552 7.5e-197 yetN S Protein of unknown function (DUF3900)
IPCOMLNL_03553 1.9e-206 yetM CH FAD binding domain
IPCOMLNL_03554 1.7e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
IPCOMLNL_03555 8.2e-106 yetJ S Belongs to the BI1 family
IPCOMLNL_03556 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
IPCOMLNL_03557 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
IPCOMLNL_03558 4.1e-153 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IPCOMLNL_03559 9.8e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPCOMLNL_03560 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
IPCOMLNL_03561 4.1e-119 yetF S membrane
IPCOMLNL_03563 1.6e-94 yesJ K Acetyltransferase (GNAT) family
IPCOMLNL_03564 8.9e-104 cotJC P Spore Coat
IPCOMLNL_03565 3.3e-45 cotJB S CotJB protein
IPCOMLNL_03566 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
IPCOMLNL_03567 3.7e-109 aadK G Streptomycin adenylyltransferase
IPCOMLNL_03570 9.4e-127 yeeN K transcriptional regulatory protein
IPCOMLNL_03571 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
IPCOMLNL_03572 2e-77 S Protein of unknown function, DUF600
IPCOMLNL_03573 2.6e-69 S Protein of unknown function, DUF600
IPCOMLNL_03574 9.9e-64 S Protein of unknown function, DUF600
IPCOMLNL_03575 1.3e-79
IPCOMLNL_03576 9.2e-73 S Domain of unknown function (DUF4411)
IPCOMLNL_03577 6.8e-159 E Pfam:DUF955
IPCOMLNL_03578 7.6e-250 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPCOMLNL_03579 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IPCOMLNL_03580 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IPCOMLNL_03581 2.4e-153 yerO K Transcriptional regulator
IPCOMLNL_03582 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPCOMLNL_03583 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IPCOMLNL_03584 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPCOMLNL_03585 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPCOMLNL_03586 1.7e-120 sapB S MgtC SapB transporter
IPCOMLNL_03587 1.7e-195 yerI S homoserine kinase type II (protein kinase fold)
IPCOMLNL_03588 2.6e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
IPCOMLNL_03589 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPCOMLNL_03590 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IPCOMLNL_03591 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IPCOMLNL_03592 7.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
IPCOMLNL_03593 2.4e-50 yerC S protein conserved in bacteria
IPCOMLNL_03594 2.6e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
IPCOMLNL_03595 0.0 yerA 3.5.4.2 F adenine deaminase
IPCOMLNL_03596 2.6e-25 S Protein of unknown function (DUF2892)
IPCOMLNL_03597 5.3e-234 purD 6.3.4.13 F Belongs to the GARS family
IPCOMLNL_03598 8.6e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IPCOMLNL_03599 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IPCOMLNL_03600 2.3e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IPCOMLNL_03601 1.1e-270 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IPCOMLNL_03602 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPCOMLNL_03603 7.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPCOMLNL_03604 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPCOMLNL_03605 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IPCOMLNL_03606 3.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IPCOMLNL_03607 4e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IPCOMLNL_03608 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IPCOMLNL_03609 6.1e-28 yebG S NETI protein
IPCOMLNL_03610 2e-92 yebE S UPF0316 protein
IPCOMLNL_03612 1.9e-125 yebC M Membrane
IPCOMLNL_03613 6.2e-209 pbuG S permease
IPCOMLNL_03614 5.7e-248 S Domain of unknown function (DUF4179)
IPCOMLNL_03615 3.9e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
IPCOMLNL_03616 5.1e-149 yqjV G Major Facilitator Superfamily
IPCOMLNL_03617 4.1e-135 aspC 2.6.1.1 E DegT/DnrJ/EryC1/StrS aminotransferase family
IPCOMLNL_03618 3.9e-106 pphA 5.4.2.9 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IPCOMLNL_03619 5.1e-117 F ATP-grasp domain
IPCOMLNL_03620 1.3e-139 6.3.4.18, 6.3.5.5 F 5-(carboxyamino)imidazole ribonucleotide synthase activity
IPCOMLNL_03621 1.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IPCOMLNL_03622 0.0 yebA E COG1305 Transglutaminase-like enzymes
IPCOMLNL_03623 1.4e-212 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IPCOMLNL_03624 1.5e-175 yeaC S COG0714 MoxR-like ATPases
IPCOMLNL_03625 4.9e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPCOMLNL_03626 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
IPCOMLNL_03627 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
IPCOMLNL_03628 7.2e-35 ydjO S Cold-inducible protein YdjO
IPCOMLNL_03630 9.4e-136 ydjN U Involved in the tonB-independent uptake of proteins
IPCOMLNL_03631 4.2e-62 ydjM M Lytic transglycolase
IPCOMLNL_03632 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
IPCOMLNL_03633 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
IPCOMLNL_03634 1.4e-145 rsiV S Protein of unknown function (DUF3298)
IPCOMLNL_03635 0.0 yrhL I Acyltransferase family
IPCOMLNL_03636 7.6e-151 ydjI S virion core protein (lumpy skin disease virus)
IPCOMLNL_03637 3.1e-120 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
IPCOMLNL_03638 6.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IPCOMLNL_03639 5.6e-113 pspA KT Phage shock protein A
IPCOMLNL_03640 2.3e-29 yjdJ S Domain of unknown function (DUF4306)
IPCOMLNL_03641 2.9e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
IPCOMLNL_03642 1.3e-249 gutA G MFS/sugar transport protein
IPCOMLNL_03643 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
IPCOMLNL_03644 0.0 K NB-ARC domain
IPCOMLNL_03646 1.5e-24 S Protein of unknown function (DUF4064)
IPCOMLNL_03647 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IPCOMLNL_03648 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPCOMLNL_03649 9e-125 ydiL S CAAX protease self-immunity
IPCOMLNL_03650 1.7e-27 ydiK S Domain of unknown function (DUF4305)
IPCOMLNL_03651 3.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPCOMLNL_03652 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IPCOMLNL_03653 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IPCOMLNL_03654 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IPCOMLNL_03655 0.0 ydiF S ABC transporter
IPCOMLNL_03656 3e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IPCOMLNL_03657 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IPCOMLNL_03658 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
IPCOMLNL_03659 2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
IPCOMLNL_03660 3.3e-183 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IPCOMLNL_03662 7.8e-08
IPCOMLNL_03663 9.8e-39 S Sulphur transport
IPCOMLNL_03664 5.8e-26 yieH 3.1.3.18 S hydrolase
IPCOMLNL_03669 3.3e-248 iolT EGP Major facilitator Superfamily
IPCOMLNL_03670 6.8e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
IPCOMLNL_03671 3.5e-82 yndB S Activator of Hsp90 ATPase homolog 1-like protein
IPCOMLNL_03672 8.7e-164 ydhU P Catalase
IPCOMLNL_03673 9.3e-297 yveA E amino acid
IPCOMLNL_03674 5.3e-104 yvdT K Transcriptional regulator
IPCOMLNL_03675 2.3e-51 ykkC P Small Multidrug Resistance protein
IPCOMLNL_03676 2.6e-49 sugE P Small Multidrug Resistance protein
IPCOMLNL_03677 7.4e-217 yeaN P COG2807 Cyanate permease
IPCOMLNL_03678 4.9e-117 K FCD
IPCOMLNL_03679 1.3e-133 ydhQ K UTRA
IPCOMLNL_03680 3.4e-195 pbuE EGP Major facilitator Superfamily
IPCOMLNL_03681 7.2e-98 ydhK M Protein of unknown function (DUF1541)
IPCOMLNL_03683 6.5e-262 pbpE V Beta-lactamase
IPCOMLNL_03686 9.2e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IPCOMLNL_03687 8.1e-120 ydhC K FCD
IPCOMLNL_03688 6.1e-167 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Isocitrate/isopropylmalate dehydrogenase
IPCOMLNL_03689 1.7e-145 ycgJ_1 Q ubiE/COQ5 methyltransferase family
IPCOMLNL_03690 1.3e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
IPCOMLNL_03691 6.9e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IPCOMLNL_03692 2.6e-149 bltR K helix_turn_helix, mercury resistance
IPCOMLNL_03693 2.9e-81 bltD 2.3.1.57 K FR47-like protein
IPCOMLNL_03694 8.5e-123 ydhB S membrane transporter protein
IPCOMLNL_03695 1.3e-156 K Helix-turn-helix XRE-family like proteins
IPCOMLNL_03696 6.8e-226 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IPCOMLNL_03697 1.1e-209 tcaB EGP Major facilitator Superfamily
IPCOMLNL_03698 1.1e-195 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
IPCOMLNL_03699 5.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
IPCOMLNL_03700 2.7e-99 ynaD J Acetyltransferase (GNAT) domain
IPCOMLNL_03701 1.8e-298 expZ S ABC transporter
IPCOMLNL_03702 3e-133 puuD S Peptidase C26
IPCOMLNL_03703 0.0 ydfJ S drug exporters of the RND superfamily
IPCOMLNL_03704 2.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPCOMLNL_03705 5.1e-216 ydfH 2.7.13.3 T Histidine kinase
IPCOMLNL_03706 4.1e-24 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IPCOMLNL_03707 1.7e-76 2.7.1.2 GK Transcriptional regulator
IPCOMLNL_03708 2.5e-108 ybjJ G Major Facilitator Superfamily
IPCOMLNL_03709 4.5e-36 yraG
IPCOMLNL_03710 2.9e-63 yraF M Spore coat protein
IPCOMLNL_03711 1.6e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IPCOMLNL_03712 1.1e-24 yraE
IPCOMLNL_03713 9.5e-49 yraD M Spore coat protein
IPCOMLNL_03714 6.8e-267 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPCOMLNL_03715 9.1e-156 ydeK EG -transporter
IPCOMLNL_03716 1.3e-102 ydeS K Transcriptional regulator
IPCOMLNL_03717 1.7e-181 ydeR EGP Major facilitator Superfamily
IPCOMLNL_03719 4.2e-115 paiB K Transcriptional regulator
IPCOMLNL_03720 3.9e-262 K helix_turn_helix gluconate operon transcriptional repressor
IPCOMLNL_03721 1.7e-211 mleN_2 C antiporter
IPCOMLNL_03722 1.4e-66 yraB K helix_turn_helix, mercury resistance
IPCOMLNL_03723 6.4e-201 adhA 1.1.1.1 C alcohol dehydrogenase
IPCOMLNL_03724 2e-164 S Sodium Bile acid symporter family
IPCOMLNL_03725 4.1e-231 3.1.3.41 G Haloacid dehalogenase-like hydrolase
IPCOMLNL_03726 1.3e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IPCOMLNL_03727 4.6e-148 Q ubiE/COQ5 methyltransferase family
IPCOMLNL_03728 1.4e-192 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IPCOMLNL_03729 1.4e-83 F nucleoside 2-deoxyribosyltransferase
IPCOMLNL_03730 8.7e-55 ydeH
IPCOMLNL_03731 2.3e-51 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
IPCOMLNL_03732 3.8e-14 ykkA S Protein of unknown function (DUF664)
IPCOMLNL_03735 4.7e-196 trkA P Oxidoreductase
IPCOMLNL_03736 3.8e-168 czcD P COG1230 Co Zn Cd efflux system component
IPCOMLNL_03737 7e-23 3.6.1.55 F Belongs to the Nudix hydrolase family
IPCOMLNL_03738 6.1e-193 ydeG EGP Major facilitator superfamily
IPCOMLNL_03739 1e-233 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPCOMLNL_03740 4.5e-177 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IPCOMLNL_03741 1.7e-125 rhaS5 K helix_turn_helix, arabinose operon control protein
IPCOMLNL_03742 1.2e-163 E Peptidase dimerisation domain
IPCOMLNL_03743 5.5e-141 sdaC E Serine transporter
IPCOMLNL_03744 5.1e-39 yabJ 3.5.99.10 J Endoribonuclease L-PSP
IPCOMLNL_03745 4.6e-67 K COG1802 Transcriptional regulators
IPCOMLNL_03746 5.6e-116 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
IPCOMLNL_03747 6.3e-79 S DinB superfamily
IPCOMLNL_03748 1.4e-181 S Patatin-like phospholipase
IPCOMLNL_03749 4.9e-51 K Transcriptional regulator PadR-like family
IPCOMLNL_03750 3.8e-99 S Protein of unknown function (DUF2812)
IPCOMLNL_03751 1.9e-121 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IPCOMLNL_03752 2.3e-118 yrkJ S membrane transporter protein
IPCOMLNL_03753 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
IPCOMLNL_03754 3.2e-198 yrkH P Rhodanese Homology Domain
IPCOMLNL_03755 4.1e-93 yrkF OP Belongs to the sulfur carrier protein TusA family
IPCOMLNL_03756 2.1e-58 P Rhodanese Homology Domain
IPCOMLNL_03757 1.6e-82 yrkE O DsrE/DsrF/DrsH-like family
IPCOMLNL_03758 4.6e-39 yrkD S protein conserved in bacteria
IPCOMLNL_03759 5.2e-78 carD K Transcription factor
IPCOMLNL_03760 1.4e-30 cspL K Cold shock
IPCOMLNL_03761 1.4e-110 ywnB S NAD(P)H-binding
IPCOMLNL_03762 1.8e-66 ywnA K Transcriptional regulator
IPCOMLNL_03763 3.2e-64 yyaQ S YjbR
IPCOMLNL_03764 1.2e-73 maoC I N-terminal half of MaoC dehydratase
IPCOMLNL_03765 2.8e-82 S Domain of unknown function with cystatin-like fold (DUF4467)
IPCOMLNL_03766 1.1e-227 proP EGP Transporter
IPCOMLNL_03767 4.7e-151 S Serine aminopeptidase, S33
IPCOMLNL_03768 1.4e-95 ywrO S Flavodoxin-like fold
IPCOMLNL_03769 2.1e-60 LO Belongs to the peptidase S16 family
IPCOMLNL_03771 2.3e-24 S response regulator aspartate phosphatase
IPCOMLNL_03772 6.3e-47 S response regulator aspartate phosphatase
IPCOMLNL_03773 2.2e-98 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPCOMLNL_03774 3.7e-77 K Transcriptional regulator
IPCOMLNL_03775 1.4e-08 S Doxx family
IPCOMLNL_03776 1.2e-122 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IPCOMLNL_03777 7.8e-34 S LXG domain of WXG superfamily
IPCOMLNL_03778 3.2e-44
IPCOMLNL_03786 1.9e-58 ydcK S Belongs to the SprT family
IPCOMLNL_03787 1.7e-14
IPCOMLNL_03788 0.0 yhgF K COG2183 Transcriptional accessory protein
IPCOMLNL_03789 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
IPCOMLNL_03790 1.5e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPCOMLNL_03791 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IPCOMLNL_03792 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
IPCOMLNL_03793 1.7e-187 rsbU 3.1.3.3 KT phosphatase
IPCOMLNL_03794 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IPCOMLNL_03795 6.8e-57 rsbS T antagonist
IPCOMLNL_03796 6.1e-146 rsbR T Positive regulator of sigma-B
IPCOMLNL_03797 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
IPCOMLNL_03798 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IPCOMLNL_03799 6.9e-220 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IPCOMLNL_03800 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
IPCOMLNL_03801 2.3e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IPCOMLNL_03802 1.5e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
IPCOMLNL_03803 9.7e-264 ydbT S Membrane
IPCOMLNL_03804 1.3e-60 ydbS S Bacterial PH domain
IPCOMLNL_03805 2.9e-247 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IPCOMLNL_03806 4.8e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IPCOMLNL_03807 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IPCOMLNL_03808 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IPCOMLNL_03809 8.1e-120 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPCOMLNL_03810 5.8e-09 S Fur-regulated basic protein A
IPCOMLNL_03811 1.5e-10 S Fur-regulated basic protein B
IPCOMLNL_03812 3.4e-203 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
IPCOMLNL_03813 2.1e-52 ydbL
IPCOMLNL_03814 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IPCOMLNL_03815 5e-173 ydbJ V ABC transporter, ATP-binding protein
IPCOMLNL_03816 3.2e-160 ydbI S AI-2E family transporter
IPCOMLNL_03817 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPCOMLNL_03818 1.1e-118 dctR T COG4565 Response regulator of citrate malate metabolism
IPCOMLNL_03819 9.4e-300 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IPCOMLNL_03820 4.9e-201 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IPCOMLNL_03821 4.2e-155 ydbD P Catalase
IPCOMLNL_03822 5e-60 ydbC S Domain of unknown function (DUF4937
IPCOMLNL_03823 9.8e-58 ydbB G Cupin domain
IPCOMLNL_03825 1.8e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
IPCOMLNL_03826 7e-54 yvaE P Small Multidrug Resistance protein
IPCOMLNL_03827 2.9e-72 yvaD S Family of unknown function (DUF5360)
IPCOMLNL_03828 6.5e-34 ydaT
IPCOMLNL_03830 2e-225 mntH P H( )-stimulated, divalent metal cation uptake system
IPCOMLNL_03831 2.1e-39
IPCOMLNL_03832 2.4e-99
IPCOMLNL_03833 4.1e-77
IPCOMLNL_03835 3.2e-12
IPCOMLNL_03837 8.1e-42 S Histidine kinase
IPCOMLNL_03838 8.8e-119 S Histidine kinase
IPCOMLNL_03840 5.9e-68
IPCOMLNL_03841 5.3e-48 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IPCOMLNL_03842 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IPCOMLNL_03843 1.8e-75 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IPCOMLNL_03844 0.0 ydaO E amino acid
IPCOMLNL_03845 0.0 ydaN S Bacterial cellulose synthase subunit
IPCOMLNL_03846 4.2e-231 ydaM M Glycosyl transferase family group 2
IPCOMLNL_03847 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
IPCOMLNL_03848 4.3e-147 ydaK T Diguanylate cyclase, GGDEF domain
IPCOMLNL_03849 6.2e-199 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
IPCOMLNL_03850 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IPCOMLNL_03851 4.3e-74 lrpC K Transcriptional regulator
IPCOMLNL_03852 3.9e-47 ydzA EGP Major facilitator Superfamily
IPCOMLNL_03853 4.6e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IPCOMLNL_03854 3.1e-77 ydaG 1.4.3.5 S general stress protein
IPCOMLNL_03855 2.3e-113 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IPCOMLNL_03856 5.6e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
IPCOMLNL_03857 3.7e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCOMLNL_03858 7.2e-286 ydaB IQ acyl-CoA ligase
IPCOMLNL_03859 0.0 mtlR K transcriptional regulator, MtlR
IPCOMLNL_03860 2.9e-173 ydhF S Oxidoreductase
IPCOMLNL_03861 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
IPCOMLNL_03862 3.3e-55 yczJ S biosynthesis
IPCOMLNL_03864 4.6e-117 ycsK E anatomical structure formation involved in morphogenesis
IPCOMLNL_03865 1.5e-130 kipR K Transcriptional regulator
IPCOMLNL_03866 4.9e-190 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
IPCOMLNL_03867 1.7e-136 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
IPCOMLNL_03868 5.7e-149 ycsI S Belongs to the D-glutamate cyclase family
IPCOMLNL_03869 1.8e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
IPCOMLNL_03870 6e-140 ycsF S Belongs to the UPF0271 (lamB) family
IPCOMLNL_03871 1.4e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IPCOMLNL_03873 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IPCOMLNL_03874 1.2e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
IPCOMLNL_03875 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IPCOMLNL_03876 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
IPCOMLNL_03877 1.6e-55
IPCOMLNL_03878 1.9e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
IPCOMLNL_03879 2.7e-299 ycnJ P protein, homolog of Cu resistance protein CopC
IPCOMLNL_03880 7.8e-98 ycnI S protein conserved in bacteria
IPCOMLNL_03881 1.9e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPCOMLNL_03882 3.6e-149 glcU U Glucose uptake
IPCOMLNL_03883 2.1e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IPCOMLNL_03884 2.7e-220 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPCOMLNL_03885 1.4e-264 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPCOMLNL_03886 8.8e-53 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
IPCOMLNL_03887 1e-44 ycnE S Monooxygenase
IPCOMLNL_03888 1.3e-134 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
IPCOMLNL_03889 5.4e-153 ycnC K Transcriptional regulator
IPCOMLNL_03890 6.6e-249 ycnB EGP Major facilitator Superfamily
IPCOMLNL_03891 1.2e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
IPCOMLNL_03892 8.1e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
IPCOMLNL_03893 1.1e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCOMLNL_03894 1.5e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCOMLNL_03895 2.1e-252 lysC 2.7.2.4 E Belongs to the aspartokinase family
IPCOMLNL_03897 1.6e-80 S aspartate phosphatase
IPCOMLNL_03898 1.1e-259 T PhoQ Sensor
IPCOMLNL_03899 2.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPCOMLNL_03900 9e-230 yclI V ABC transporter (permease) YclI
IPCOMLNL_03901 8.7e-122 yclH P ABC transporter
IPCOMLNL_03902 7.4e-250 yxeQ S MmgE/PrpD family
IPCOMLNL_03903 3.7e-218 yxeP 3.5.1.47 E hydrolase activity
IPCOMLNL_03904 2.7e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
IPCOMLNL_03905 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
IPCOMLNL_03906 7.9e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
IPCOMLNL_03907 2.5e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPCOMLNL_03908 8.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCOMLNL_03909 1.5e-195 gerKB F Spore germination protein
IPCOMLNL_03910 6.1e-235 gerKC S spore germination
IPCOMLNL_03911 4.1e-295 gerKA EG Spore germination protein
IPCOMLNL_03913 6.1e-281 yclG M Pectate lyase superfamily protein
IPCOMLNL_03914 3.2e-270 dtpT E amino acid peptide transporter
IPCOMLNL_03916 1e-12 ydcO Q protein involved in benzoate metabolism
IPCOMLNL_03917 5.9e-64 tauA P TIGRFAM Taurine ABC transporter, periplasmic binding protein
IPCOMLNL_03919 1.6e-25 aas 2.3.1.40, 6.2.1.20 IQ Aas bifunctional protein
IPCOMLNL_03920 4.4e-77 yclD
IPCOMLNL_03921 5.8e-38 bsdD 4.1.1.61 S response to toxic substance
IPCOMLNL_03922 6.3e-284 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IPCOMLNL_03923 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IPCOMLNL_03924 1.5e-158 bsdA K LysR substrate binding domain
IPCOMLNL_03925 3.6e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IPCOMLNL_03926 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
IPCOMLNL_03927 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IPCOMLNL_03928 3.5e-109 yczE S membrane
IPCOMLNL_03929 5.5e-129 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
IPCOMLNL_03930 1.8e-248 bamJ E Aminotransferase class I and II
IPCOMLNL_03931 2.9e-139 srfAD Q thioesterase
IPCOMLNL_03932 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
IPCOMLNL_03933 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_03934 6.3e-63 hxlR K transcriptional
IPCOMLNL_03935 2.8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
IPCOMLNL_03936 6.2e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
IPCOMLNL_03937 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
IPCOMLNL_03938 3.6e-67 nin S Competence protein J (ComJ)
IPCOMLNL_03939 7.3e-296 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IPCOMLNL_03940 2.2e-51 S Protein of unknown function (DUF2680)
IPCOMLNL_03941 1.1e-72 yckC S membrane
IPCOMLNL_03942 1.4e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IPCOMLNL_03943 1.1e-228 yciC S GTPases (G3E family)
IPCOMLNL_03944 4.5e-222 nasA P COG2223 Nitrate nitrite transporter
IPCOMLNL_03945 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
IPCOMLNL_03946 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IPCOMLNL_03947 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IPCOMLNL_03948 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
IPCOMLNL_03949 1.1e-278 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IPCOMLNL_03950 1.3e-187 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IPCOMLNL_03951 6.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
IPCOMLNL_03952 5.8e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPCOMLNL_03953 5.8e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IPCOMLNL_03954 2.3e-170 ycgM E Proline dehydrogenase
IPCOMLNL_03955 1.5e-146 ycgL S Predicted nucleotidyltransferase
IPCOMLNL_03956 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
IPCOMLNL_03957 5.3e-162 oxyR3 K LysR substrate binding domain
IPCOMLNL_03958 9.6e-138 yafE Q ubiE/COQ5 methyltransferase family
IPCOMLNL_03959 4.3e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IPCOMLNL_03960 3.1e-221 G COG0477 Permeases of the major facilitator superfamily
IPCOMLNL_03961 3.9e-142 4.2.1.118 G Xylose isomerase-like TIM barrel
IPCOMLNL_03962 5.2e-107 tmrB S AAA domain
IPCOMLNL_03964 1.8e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IPCOMLNL_03965 1.3e-113 ycgI S Domain of unknown function (DUF1989)
IPCOMLNL_03966 2.2e-246 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
IPCOMLNL_03967 2.9e-150 yqcI S YqcI/YcgG family
IPCOMLNL_03968 4.7e-114 ycgF E Lysine exporter protein LysE YggA
IPCOMLNL_03969 4.1e-75 emrR K helix_turn_helix multiple antibiotic resistance protein
IPCOMLNL_03970 4e-260 mdr EGP Major facilitator Superfamily
IPCOMLNL_03971 3.7e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IPCOMLNL_03972 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
IPCOMLNL_03973 1.1e-81 ycgB
IPCOMLNL_03974 1.4e-230 ycgA S Membrane
IPCOMLNL_03975 3.9e-212 amhX S amidohydrolase
IPCOMLNL_03976 2e-163 opuAC E glycine betaine
IPCOMLNL_03977 1.6e-138 opuAB P glycine betaine
IPCOMLNL_03978 1.5e-228 proV 3.6.3.32 E glycine betaine
IPCOMLNL_03979 9e-215 naiP P Uncharacterised MFS-type transporter YbfB
IPCOMLNL_03980 2.3e-193 yceH P Belongs to the TelA family
IPCOMLNL_03981 0.0 yceG S Putative component of 'biosynthetic module'
IPCOMLNL_03982 9.7e-138 terC P Protein of unknown function (DUF475)
IPCOMLNL_03983 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
IPCOMLNL_03984 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
IPCOMLNL_03985 6.2e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
IPCOMLNL_03986 1.4e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCOMLNL_03987 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IPCOMLNL_03988 7.2e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IPCOMLNL_03989 1e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
IPCOMLNL_03990 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
IPCOMLNL_03991 1.5e-138 IQ Enoyl-(Acyl carrier protein) reductase
IPCOMLNL_03992 1.9e-187 S response regulator aspartate phosphatase
IPCOMLNL_03993 6.4e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
IPCOMLNL_03994 4.8e-265 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
IPCOMLNL_03995 1.4e-251 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
IPCOMLNL_03996 3.4e-175 ycdA S Domain of unknown function (DUF5105)
IPCOMLNL_03997 9.5e-172 yccK C Aldo keto reductase
IPCOMLNL_03998 8.6e-193 yccF K DNA-templated transcriptional preinitiation complex assembly
IPCOMLNL_03999 2.8e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
IPCOMLNL_04000 1.9e-198 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IPCOMLNL_04001 5.9e-100 yxaF K Transcriptional regulator
IPCOMLNL_04002 2.1e-242 lmrB EGP the major facilitator superfamily
IPCOMLNL_04003 7.6e-208 ycbU E Selenocysteine lyase
IPCOMLNL_04004 1.2e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IPCOMLNL_04005 4e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPCOMLNL_04006 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IPCOMLNL_04007 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
IPCOMLNL_04008 5.3e-77 sleB 3.5.1.28 M Cell wall
IPCOMLNL_04009 5.6e-62 ycbP S Protein of unknown function (DUF2512)
IPCOMLNL_04010 1.5e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
IPCOMLNL_04011 4.6e-126 ycbJ S Macrolide 2'-phosphotransferase
IPCOMLNL_04013 1.6e-171 glnL T Regulator
IPCOMLNL_04014 2.7e-209 phoQ 2.7.13.3 T Histidine kinase
IPCOMLNL_04015 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
IPCOMLNL_04016 1.1e-256 agcS E Sodium alanine symporter
IPCOMLNL_04017 5.1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
IPCOMLNL_04018 1.3e-255 mmuP E amino acid
IPCOMLNL_04019 1.9e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IPCOMLNL_04020 4.2e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPCOMLNL_04021 2.3e-192 yceA S Belongs to the UPF0176 family
IPCOMLNL_04022 2.3e-41 ybfN
IPCOMLNL_04023 5.6e-152 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IPCOMLNL_04024 2.5e-86 ybfM S SNARE associated Golgi protein
IPCOMLNL_04025 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IPCOMLNL_04026 2.6e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IPCOMLNL_04027 1.5e-200 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
IPCOMLNL_04028 1.2e-82 K Helix-turn-helix XRE-family like proteins
IPCOMLNL_04029 9.5e-29
IPCOMLNL_04030 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
IPCOMLNL_04032 5e-212 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
IPCOMLNL_04033 1.3e-16 S Protein of unknown function (DUF2651)
IPCOMLNL_04034 1.7e-259 glpT G -transporter
IPCOMLNL_04035 2.8e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IPCOMLNL_04036 3.4e-15 S Protein of unknown function (DUF2651)
IPCOMLNL_04037 1.4e-53
IPCOMLNL_04039 4.1e-13 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IPCOMLNL_04040 3.5e-48 M PFAM Glycosyl transferase family 2
IPCOMLNL_04041 9.5e-292 ybeC E amino acid
IPCOMLNL_04042 9.2e-40 ybyB
IPCOMLNL_04043 1.8e-106 yqeB
IPCOMLNL_04044 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
IPCOMLNL_04045 4.5e-77 S Domain of unknown function (DUF4879)
IPCOMLNL_04046 2.2e-24
IPCOMLNL_04047 7.8e-200 V ABC-2 family transporter protein
IPCOMLNL_04048 2.9e-205 V COG0842 ABC-type multidrug transport system, permease component
IPCOMLNL_04049 2.7e-166 V COG1131 ABC-type multidrug transport system, ATPase component
IPCOMLNL_04050 6.7e-108 KT LuxR family transcriptional regulator
IPCOMLNL_04051 3.7e-202 T COG4585 Signal transduction histidine kinase
IPCOMLNL_04052 9.4e-95 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IPCOMLNL_04053 4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
IPCOMLNL_04055 3.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
IPCOMLNL_04056 1.5e-51 S LrgA family
IPCOMLNL_04057 2.2e-93 yxaC M effector of murein hydrolase
IPCOMLNL_04058 2.8e-162 dkgB S Aldo/keto reductase family
IPCOMLNL_04059 2.7e-131 ybdO S Domain of unknown function (DUF4885)
IPCOMLNL_04060 1.6e-99 ybdN
IPCOMLNL_04061 1.7e-106 S ABC-2 family transporter protein
IPCOMLNL_04062 4.9e-154 V ATPases associated with a variety of cellular activities
IPCOMLNL_04063 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IPCOMLNL_04064 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPCOMLNL_04065 4.4e-224 ybbR S protein conserved in bacteria
IPCOMLNL_04066 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IPCOMLNL_04067 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IPCOMLNL_04068 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
IPCOMLNL_04074 8.7e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
IPCOMLNL_04075 9.1e-86 ybbJ J acetyltransferase
IPCOMLNL_04076 2.2e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IPCOMLNL_04077 1e-238 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IPCOMLNL_04078 6.8e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
IPCOMLNL_04079 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
IPCOMLNL_04080 8.6e-237 ybbC 3.2.1.52 S protein conserved in bacteria
IPCOMLNL_04081 1.1e-310 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
IPCOMLNL_04082 2e-172 feuA P Iron-uptake system-binding protein
IPCOMLNL_04083 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCOMLNL_04084 5.2e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPCOMLNL_04085 7.6e-111 ybbA S Putative esterase
IPCOMLNL_04086 8.2e-174 ybaS 1.1.1.58 S Na -dependent transporter
IPCOMLNL_04087 6e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
IPCOMLNL_04088 2.6e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
IPCOMLNL_04089 4.3e-180 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
IPCOMLNL_04090 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPCOMLNL_04091 2.3e-218 glcP G Major Facilitator Superfamily
IPCOMLNL_04093 3.4e-29 S Trm112p-like protein
IPCOMLNL_04094 1.7e-31 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IPCOMLNL_04095 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_04096 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
IPCOMLNL_04097 1.2e-64 yngL S Protein of unknown function (DUF1360)
IPCOMLNL_04098 3.8e-303 yngK T Glycosyl hydrolase-like 10
IPCOMLNL_04099 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
IPCOMLNL_04100 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IPCOMLNL_04101 2.1e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
IPCOMLNL_04102 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
IPCOMLNL_04103 4.3e-169 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
IPCOMLNL_04104 4.9e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IPCOMLNL_04105 7e-289 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IPCOMLNL_04106 3.2e-104 yngC S SNARE associated Golgi protein
IPCOMLNL_04107 1.5e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IPCOMLNL_04108 3.7e-72 yngA S membrane
IPCOMLNL_04109 6.9e-144 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IPCOMLNL_04110 1.7e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IPCOMLNL_04111 3.4e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IPCOMLNL_04112 1.3e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IPCOMLNL_04113 8.2e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IPCOMLNL_04114 2.9e-221 bioI 1.14.14.46 C Cytochrome P450
IPCOMLNL_04115 5.9e-253 yxjC EG COG2610 H gluconate symporter and related permeases
IPCOMLNL_04116 2.9e-125 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IPCOMLNL_04117 7.8e-120 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IPCOMLNL_04118 6.9e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IPCOMLNL_04119 4.3e-225 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IPCOMLNL_04120 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_04121 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_04122 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPCOMLNL_04123 7.8e-288 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
IPCOMLNL_04124 2.6e-252 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
IPCOMLNL_04125 2.6e-129 T Transcriptional regulatory protein, C terminal
IPCOMLNL_04126 5.3e-235 T PhoQ Sensor
IPCOMLNL_04127 1.3e-51 S Domain of unknown function (DUF4870)
IPCOMLNL_04128 6.6e-292 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
IPCOMLNL_04129 1.4e-11
IPCOMLNL_04131 1.5e-64 V ABC transporter
IPCOMLNL_04132 8.3e-86
IPCOMLNL_04133 3.8e-301 yndJ S YndJ-like protein
IPCOMLNL_04134 1.1e-78 yndH S Domain of unknown function (DUF4166)
IPCOMLNL_04135 6.4e-156 yndG S DoxX-like family
IPCOMLNL_04136 7.7e-225 exuT G Sugar (and other) transporter
IPCOMLNL_04137 2.4e-181 kdgR_1 K transcriptional
IPCOMLNL_04138 7.8e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IPCOMLNL_04139 1.4e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
IPCOMLNL_04140 2.6e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
IPCOMLNL_04141 7.2e-189 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
IPCOMLNL_04142 2.3e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
IPCOMLNL_04143 1.6e-250 agcS E Sodium alanine symporter
IPCOMLNL_04144 4.7e-39 ynfC
IPCOMLNL_04145 6e-13
IPCOMLNL_04146 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IPCOMLNL_04147 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IPCOMLNL_04148 1.5e-68 yccU S CoA-binding protein
IPCOMLNL_04149 1.4e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IPCOMLNL_04150 1.3e-50 yneR S Belongs to the HesB IscA family
IPCOMLNL_04151 3.7e-53 yneQ
IPCOMLNL_04152 8.3e-75 yneP S Thioesterase-like superfamily
IPCOMLNL_04153 2.7e-33 tlp S Belongs to the Tlp family
IPCOMLNL_04156 1.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IPCOMLNL_04157 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IPCOMLNL_04158 7.5e-15 sspO S Belongs to the SspO family
IPCOMLNL_04159 2.3e-19 sspP S Belongs to the SspP family
IPCOMLNL_04160 3.2e-62 hspX O Spore coat protein
IPCOMLNL_04161 1.2e-73 yneK S Protein of unknown function (DUF2621)
IPCOMLNL_04162 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
IPCOMLNL_04163 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
IPCOMLNL_04164 1.7e-125 ccdA O cytochrome c biogenesis protein
IPCOMLNL_04165 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
IPCOMLNL_04166 2.3e-28 yneF S UPF0154 protein
IPCOMLNL_04167 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
IPCOMLNL_04168 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IPCOMLNL_04169 9.8e-33 ynzC S UPF0291 protein
IPCOMLNL_04170 7.7e-112 yneB L resolvase
IPCOMLNL_04171 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IPCOMLNL_04172 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IPCOMLNL_04173 1.7e-11 yoaW
IPCOMLNL_04174 6.6e-70 yndM S Protein of unknown function (DUF2512)
IPCOMLNL_04175 1.4e-137 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
IPCOMLNL_04177 1.3e-143 yndL S Replication protein
IPCOMLNL_04178 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
IPCOMLNL_04179 0.0 yobO M Pectate lyase superfamily protein
IPCOMLNL_04181 3.5e-94 yvgO
IPCOMLNL_04183 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
IPCOMLNL_04184 4.6e-202 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPCOMLNL_04185 4.8e-119 ynaE S Domain of unknown function (DUF3885)
IPCOMLNL_04187 4.5e-35
IPCOMLNL_04189 1.1e-50 yokK S SMI1 / KNR4 family
IPCOMLNL_04190 2.4e-51 S SMI1-KNR4 cell-wall
IPCOMLNL_04191 4.7e-173 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)