ORF_ID e_value Gene_name EC_number CAZy COGs Description
NMLFEMLE_00001 5.1e-125 pks13 HQ Beta-ketoacyl synthase
NMLFEMLE_00002 4.1e-139 cypA C Cytochrome P450
NMLFEMLE_00003 3.5e-34 cypA C Cytochrome P450
NMLFEMLE_00004 8.9e-26 ymzB
NMLFEMLE_00005 1.2e-59 ymaE S Metallo-beta-lactamase superfamily
NMLFEMLE_00006 2.9e-63 ymaE S Metallo-beta-lactamase superfamily
NMLFEMLE_00007 8.3e-14 ymaE S Metallo-beta-lactamase superfamily
NMLFEMLE_00008 8.7e-26 aprX O Belongs to the peptidase S8 family
NMLFEMLE_00009 4.6e-191 aprX O Belongs to the peptidase S8 family
NMLFEMLE_00010 1.9e-07 K Transcriptional regulator
NMLFEMLE_00011 1.7e-82 ymaC S Replication protein
NMLFEMLE_00012 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
NMLFEMLE_00013 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NMLFEMLE_00015 2.3e-25 ymaF S YmaF family
NMLFEMLE_00016 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NMLFEMLE_00017 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NMLFEMLE_00018 4.1e-22
NMLFEMLE_00019 4.5e-22 ymzA
NMLFEMLE_00020 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NMLFEMLE_00021 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMLFEMLE_00022 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMLFEMLE_00023 1e-108 ymaB
NMLFEMLE_00024 6.3e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMLFEMLE_00025 2.4e-97 spoVK O stage V sporulation protein K
NMLFEMLE_00027 5.8e-81 yhbS S family acetyltransferase
NMLFEMLE_00028 1.1e-105 yokF 3.1.31.1 L RNA catabolic process
NMLFEMLE_00029 1e-35
NMLFEMLE_00030 1.2e-65 G SMI1-KNR4 cell-wall
NMLFEMLE_00031 7.2e-213 UW nuclease activity
NMLFEMLE_00032 1.6e-87 yokK S SMI1 / KNR4 family
NMLFEMLE_00034 1.9e-45
NMLFEMLE_00035 1e-51 S YolD-like protein
NMLFEMLE_00036 1.2e-233 S impB/mucB/samB family C-terminal domain
NMLFEMLE_00038 7.2e-190 S aspartate phosphatase
NMLFEMLE_00039 6.4e-38 S Bacteriophage holin
NMLFEMLE_00041 4.1e-182 S N-acetylmuramoyl-L-alanine amidase activity
NMLFEMLE_00042 7.6e-162
NMLFEMLE_00043 1e-183 M Pectate lyase superfamily protein
NMLFEMLE_00044 2.2e-119
NMLFEMLE_00045 1.5e-242 S Pfam Transposase IS66
NMLFEMLE_00046 8.5e-86 S Phage tail protein
NMLFEMLE_00047 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NMLFEMLE_00048 5.8e-110
NMLFEMLE_00050 2.2e-22
NMLFEMLE_00051 3.1e-71 xerH A Belongs to the 'phage' integrase family
NMLFEMLE_00052 4.5e-106 xerH A Belongs to the 'phage' integrase family
NMLFEMLE_00053 2.3e-56
NMLFEMLE_00054 2.5e-54
NMLFEMLE_00055 4.8e-98 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
NMLFEMLE_00056 1.6e-07 S Phage uncharacterised protein (Phage_XkdX)
NMLFEMLE_00057 2.1e-08
NMLFEMLE_00058 1.5e-35 S Domain of unknown function (DUF2479)
NMLFEMLE_00059 1.2e-45
NMLFEMLE_00062 3.2e-59
NMLFEMLE_00063 1e-72
NMLFEMLE_00064 8.8e-79
NMLFEMLE_00065 7e-121
NMLFEMLE_00067 3.7e-49
NMLFEMLE_00068 1.1e-80
NMLFEMLE_00069 2.8e-185
NMLFEMLE_00070 7.8e-94
NMLFEMLE_00071 3.2e-243
NMLFEMLE_00072 1.9e-278
NMLFEMLE_00073 0.0 gp17a S Terminase-like family
NMLFEMLE_00074 1.8e-175
NMLFEMLE_00078 4.3e-225 S hydrolase activity
NMLFEMLE_00081 5.6e-236
NMLFEMLE_00082 9.5e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NMLFEMLE_00083 5.8e-94
NMLFEMLE_00084 0.0 S RNA-directed RNA polymerase activity
NMLFEMLE_00087 6.1e-203
NMLFEMLE_00088 5.9e-22 kilA K SOS response
NMLFEMLE_00090 3.6e-12 K Helix-turn-helix XRE-family like proteins
NMLFEMLE_00099 3.1e-103
NMLFEMLE_00104 5.4e-195 L Belongs to the 'phage' integrase family
NMLFEMLE_00105 1.1e-261 S DNA-sulfur modification-associated
NMLFEMLE_00106 4.6e-177
NMLFEMLE_00107 1.1e-33 K Transcriptional regulator
NMLFEMLE_00111 6.2e-42
NMLFEMLE_00117 4e-266 3.1.3.16, 3.1.4.37 T phosphatase
NMLFEMLE_00122 1.5e-94 S Protein of unknown function (DUF1273)
NMLFEMLE_00127 6.9e-74
NMLFEMLE_00128 7.1e-147 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
NMLFEMLE_00129 6.1e-128 yoqW S Belongs to the SOS response-associated peptidase family
NMLFEMLE_00131 1e-159
NMLFEMLE_00134 1.1e-101 S Pfam:DUF867
NMLFEMLE_00135 0.0 M Parallel beta-helix repeats
NMLFEMLE_00139 3.6e-155
NMLFEMLE_00140 1.9e-89 L AAA domain
NMLFEMLE_00141 1.8e-23 L AAA domain
NMLFEMLE_00142 1.2e-85
NMLFEMLE_00143 3.9e-284 3.6.4.12 J DnaB-like helicase C terminal domain
NMLFEMLE_00144 3.8e-223 L DNA primase activity
NMLFEMLE_00145 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NMLFEMLE_00146 0.0 S Bacterial DNA polymerase III alpha subunit
NMLFEMLE_00147 4.7e-54 DR0488 S protein conserved in bacteria
NMLFEMLE_00148 4e-50 DR0488 S protein conserved in bacteria
NMLFEMLE_00153 1.4e-84 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
NMLFEMLE_00154 8.7e-90 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
NMLFEMLE_00156 5.1e-146 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
NMLFEMLE_00162 3.5e-25 S hydrolase activity
NMLFEMLE_00171 3.8e-10 larC 4.99.1.12 FJ Protein conserved in bacteria
NMLFEMLE_00176 7.9e-67 S NrdI Flavodoxin like
NMLFEMLE_00177 1.8e-114 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMLFEMLE_00178 5.5e-196 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMLFEMLE_00180 8.3e-105 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMLFEMLE_00181 4.5e-86 L HNH endonuclease
NMLFEMLE_00182 3.2e-62 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMLFEMLE_00183 1.4e-34 O Glutaredoxin
NMLFEMLE_00185 5.4e-51 pth_2 3.1.1.29 S Peptidyl-tRNA hydrolase PTH2
NMLFEMLE_00187 1.1e-09
NMLFEMLE_00188 3.6e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NMLFEMLE_00193 1.5e-160 S Thymidylate synthase
NMLFEMLE_00194 5.4e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NMLFEMLE_00196 7e-36
NMLFEMLE_00199 1.3e-23 sspB S spore protein
NMLFEMLE_00209 4.1e-10 K Cro/C1-type HTH DNA-binding domain
NMLFEMLE_00210 1.1e-93 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NMLFEMLE_00212 1.4e-22 cisA2 L Recombinase
NMLFEMLE_00213 7.9e-213 cisA2 L Recombinase
NMLFEMLE_00214 8.7e-69 spoVK O stage V sporulation protein K
NMLFEMLE_00215 6.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NMLFEMLE_00216 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NMLFEMLE_00217 1.1e-68 glnR K transcriptional
NMLFEMLE_00218 7e-261 glnA 6.3.1.2 E glutamine synthetase
NMLFEMLE_00219 3.8e-10
NMLFEMLE_00220 6.6e-31
NMLFEMLE_00221 2.3e-10 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMLFEMLE_00222 2.5e-69 Q Collagen triple helix repeat (20 copies)
NMLFEMLE_00223 5.7e-94 M Glycosyltransferase like family
NMLFEMLE_00224 3.4e-121 H Methionine biosynthesis protein MetW
NMLFEMLE_00225 1.4e-193 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NMLFEMLE_00226 4.9e-217 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
NMLFEMLE_00228 2e-97 ynaD J Acetyltransferase (GNAT) domain
NMLFEMLE_00229 6.1e-75 S CAAX protease self-immunity
NMLFEMLE_00230 4.7e-08 S Uncharacterised protein family (UPF0715)
NMLFEMLE_00231 1.5e-22 K Cro/C1-type HTH DNA-binding domain
NMLFEMLE_00232 1.7e-111 ynaE S Domain of unknown function (DUF3885)
NMLFEMLE_00235 3.2e-75 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NMLFEMLE_00236 1.6e-38 yhbS S family acetyltransferase
NMLFEMLE_00237 7.5e-225 xynT G MFS/sugar transport protein
NMLFEMLE_00238 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NMLFEMLE_00239 3.1e-212 xylR GK ROK family
NMLFEMLE_00240 3.2e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NMLFEMLE_00241 4.7e-185 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NMLFEMLE_00242 1.7e-66 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NMLFEMLE_00243 1.1e-110 yokF 3.1.31.1 L RNA catabolic process
NMLFEMLE_00244 1.8e-254 iolT EGP Major facilitator Superfamily
NMLFEMLE_00245 1e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMLFEMLE_00246 2.4e-83 yncE S Protein of unknown function (DUF2691)
NMLFEMLE_00247 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NMLFEMLE_00248 5.2e-15
NMLFEMLE_00251 1.9e-163 S Thymidylate synthase
NMLFEMLE_00253 7e-133 S Domain of unknown function, YrpD
NMLFEMLE_00256 7.9e-25 tatA U protein secretion
NMLFEMLE_00257 5.3e-71
NMLFEMLE_00258 7.3e-50 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NMLFEMLE_00261 3.4e-283 gerAA EG Spore germination protein
NMLFEMLE_00262 9.1e-136 gerAB U Spore germination
NMLFEMLE_00263 6.1e-219 gerLC S Spore germination protein
NMLFEMLE_00264 3.5e-132 yndG S DoxX-like family
NMLFEMLE_00265 7.4e-116 yndH S Domain of unknown function (DUF4166)
NMLFEMLE_00266 1.8e-306 yndJ S YndJ-like protein
NMLFEMLE_00268 4.7e-137 yndL S Replication protein
NMLFEMLE_00269 3.7e-73 yndM S Protein of unknown function (DUF2512)
NMLFEMLE_00270 8.9e-32 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NMLFEMLE_00271 2.2e-16 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NMLFEMLE_00272 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NMLFEMLE_00273 9.9e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NMLFEMLE_00274 4.5e-112 yneB L resolvase
NMLFEMLE_00275 1.3e-32 ynzC S UPF0291 protein
NMLFEMLE_00276 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NMLFEMLE_00277 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NMLFEMLE_00278 1.8e-28 yneF S UPF0154 protein
NMLFEMLE_00279 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NMLFEMLE_00280 7.1e-127 ccdA O cytochrome c biogenesis protein
NMLFEMLE_00281 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NMLFEMLE_00282 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NMLFEMLE_00283 7.2e-74 yneK S Protein of unknown function (DUF2621)
NMLFEMLE_00284 5.9e-64 hspX O Spore coat protein
NMLFEMLE_00285 3.9e-19 sspP S Belongs to the SspP family
NMLFEMLE_00286 2.2e-14 sspO S Belongs to the SspO family
NMLFEMLE_00287 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NMLFEMLE_00288 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NMLFEMLE_00290 3.1e-08 sspN S Small acid-soluble spore protein N family
NMLFEMLE_00291 1.1e-34 tlp S Belongs to the Tlp family
NMLFEMLE_00292 1.2e-73 yneP S Thioesterase-like superfamily
NMLFEMLE_00293 1.3e-53 yneQ
NMLFEMLE_00294 4.1e-49 yneR S Belongs to the HesB IscA family
NMLFEMLE_00295 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NMLFEMLE_00296 6.6e-69 yccU S CoA-binding protein
NMLFEMLE_00297 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMLFEMLE_00298 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMLFEMLE_00299 2.3e-12
NMLFEMLE_00300 1.3e-57 ynfC
NMLFEMLE_00301 9e-251 agcS E Sodium alanine symporter
NMLFEMLE_00302 6e-293 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NMLFEMLE_00304 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NMLFEMLE_00305 4.7e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NMLFEMLE_00306 2e-79 yngA S membrane
NMLFEMLE_00307 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NMLFEMLE_00308 5.5e-104 yngC S membrane-associated protein
NMLFEMLE_00309 3.3e-233 nrnB S phosphohydrolase (DHH superfamily)
NMLFEMLE_00310 4.5e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NMLFEMLE_00311 3.2e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NMLFEMLE_00312 1.5e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NMLFEMLE_00313 1.7e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NMLFEMLE_00314 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NMLFEMLE_00315 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NMLFEMLE_00316 1.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NMLFEMLE_00318 1.9e-302 yngK T Glycosyl hydrolase-like 10
NMLFEMLE_00319 2.8e-64 yngL S Protein of unknown function (DUF1360)
NMLFEMLE_00320 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NMLFEMLE_00321 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMLFEMLE_00322 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMLFEMLE_00323 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMLFEMLE_00324 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMLFEMLE_00325 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMLFEMLE_00326 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMLFEMLE_00327 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMLFEMLE_00328 6.8e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NMLFEMLE_00329 2.1e-190 yoxA 5.1.3.3 G Aldose 1-epimerase
NMLFEMLE_00330 2.3e-246 yoeA V MATE efflux family protein
NMLFEMLE_00331 1.8e-98 yoeB S IseA DL-endopeptidase inhibitor
NMLFEMLE_00333 2.2e-96 L Integrase
NMLFEMLE_00334 3e-34 yoeD G Helix-turn-helix domain
NMLFEMLE_00335 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NMLFEMLE_00336 9.4e-124 gltR1 K Transcriptional regulator
NMLFEMLE_00337 1.3e-20 gltR1 K Transcriptional regulator
NMLFEMLE_00338 6.7e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NMLFEMLE_00339 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NMLFEMLE_00340 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NMLFEMLE_00341 7.8e-155 gltC K Transcriptional regulator
NMLFEMLE_00342 7.8e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMLFEMLE_00343 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMLFEMLE_00344 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NMLFEMLE_00345 6.3e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NMLFEMLE_00346 6e-38 yoxC S Bacterial protein of unknown function (DUF948)
NMLFEMLE_00347 3.1e-128 yoxB
NMLFEMLE_00348 1.1e-16 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMLFEMLE_00349 8.9e-234 yoaB EGP Major facilitator Superfamily
NMLFEMLE_00350 2.2e-279 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NMLFEMLE_00351 2.9e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMLFEMLE_00352 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMLFEMLE_00353 1.9e-33 yoaF
NMLFEMLE_00354 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
NMLFEMLE_00355 2.6e-13
NMLFEMLE_00356 8.2e-37 S Protein of unknown function (DUF4025)
NMLFEMLE_00357 1.9e-178 mcpU NT methyl-accepting chemotaxis protein
NMLFEMLE_00358 8.1e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NMLFEMLE_00359 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NMLFEMLE_00360 6.8e-111 yoaK S Membrane
NMLFEMLE_00361 7.3e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NMLFEMLE_00362 1.6e-131 yoqW S Belongs to the SOS response-associated peptidase family
NMLFEMLE_00365 5.6e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
NMLFEMLE_00367 3.2e-50 yoaP 3.1.3.18 K YoaP-like
NMLFEMLE_00368 6.2e-81 yoaP 3.1.3.18 K YoaP-like
NMLFEMLE_00369 3.5e-51 yoaQ S Evidence 4 Homologs of previously reported genes of
NMLFEMLE_00371 3e-87
NMLFEMLE_00372 1.1e-152 yoaR V vancomycin resistance protein
NMLFEMLE_00373 2.8e-74 yoaS S Protein of unknown function (DUF2975)
NMLFEMLE_00374 1.6e-36 yozG K Transcriptional regulator
NMLFEMLE_00375 1.1e-147 yoaT S Protein of unknown function (DUF817)
NMLFEMLE_00376 5.6e-158 yoaU K LysR substrate binding domain
NMLFEMLE_00377 1.3e-12 yijE EG EamA-like transporter family
NMLFEMLE_00378 2.1e-117 yijE EG EamA-like transporter family
NMLFEMLE_00379 1e-75 yoaW
NMLFEMLE_00380 4.7e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NMLFEMLE_00381 2.2e-168 bla 3.5.2.6 V beta-lactamase
NMLFEMLE_00384 2.8e-16 pps 2.7.9.2 GT Phosphoenolpyruvate synthase
NMLFEMLE_00385 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NMLFEMLE_00386 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NMLFEMLE_00389 2.1e-31 K Helix-turn-helix
NMLFEMLE_00394 1.7e-39 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMLFEMLE_00395 4.8e-102 yokH G SMI1 / KNR4 family
NMLFEMLE_00396 3.7e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NMLFEMLE_00397 0.0 yobO M Pectate lyase superfamily protein
NMLFEMLE_00398 7.8e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NMLFEMLE_00399 2.3e-133 yobQ K helix_turn_helix, arabinose operon control protein
NMLFEMLE_00400 1.1e-141 yobR 2.3.1.1 J FR47-like protein
NMLFEMLE_00401 2.3e-51 yobS K Transcriptional regulator
NMLFEMLE_00402 4.1e-13 yobS K Transcriptional regulator
NMLFEMLE_00403 1e-130 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NMLFEMLE_00404 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
NMLFEMLE_00405 1.7e-142 yobV K WYL domain
NMLFEMLE_00406 3.3e-19 yobV K WYL domain
NMLFEMLE_00407 8.8e-93 yobW
NMLFEMLE_00408 1e-51 czrA K transcriptional
NMLFEMLE_00409 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NMLFEMLE_00410 1.5e-92 yozB S membrane
NMLFEMLE_00411 1.4e-101
NMLFEMLE_00412 2.4e-12
NMLFEMLE_00413 1.6e-93 yocC
NMLFEMLE_00414 9.3e-186 yocD 3.4.17.13 V peptidase S66
NMLFEMLE_00415 4.5e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NMLFEMLE_00416 4.6e-197 desK 2.7.13.3 T Histidine kinase
NMLFEMLE_00417 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMLFEMLE_00418 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
NMLFEMLE_00419 0.0 recQ 3.6.4.12 L DNA helicase
NMLFEMLE_00420 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NMLFEMLE_00421 5e-57 dksA T general stress protein
NMLFEMLE_00422 4.4e-11 dksA T general stress protein
NMLFEMLE_00423 1.4e-53 yocL
NMLFEMLE_00424 2e-30
NMLFEMLE_00425 1.8e-86 yocM O Belongs to the small heat shock protein (HSP20) family
NMLFEMLE_00426 1.1e-40 yozN
NMLFEMLE_00427 1.9e-36 yocN
NMLFEMLE_00428 4.2e-56 yozO S Bacterial PH domain
NMLFEMLE_00429 2.7e-31 yozC
NMLFEMLE_00430 1.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NMLFEMLE_00431 2.7e-86 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NMLFEMLE_00432 1.4e-122 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NMLFEMLE_00433 4.2e-102 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NMLFEMLE_00434 8.7e-164 sodA 1.15.1.1 P Superoxide dismutase
NMLFEMLE_00435 4.5e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NMLFEMLE_00436 5.1e-168 yocS S -transporter
NMLFEMLE_00437 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NMLFEMLE_00438 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NMLFEMLE_00439 0.0 yojO P Von Willebrand factor
NMLFEMLE_00440 2.1e-160 yojN S ATPase family associated with various cellular activities (AAA)
NMLFEMLE_00441 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NMLFEMLE_00442 1.2e-190 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NMLFEMLE_00443 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NMLFEMLE_00444 7.6e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMLFEMLE_00446 7.2e-245 norM V Multidrug efflux pump
NMLFEMLE_00447 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMLFEMLE_00448 2.1e-125 yojG S deacetylase
NMLFEMLE_00449 1.4e-59 yojF S Protein of unknown function (DUF1806)
NMLFEMLE_00450 1.5e-43
NMLFEMLE_00451 1.2e-160 rarD S -transporter
NMLFEMLE_00452 2e-56 yozR S COG0071 Molecular chaperone (small heat shock protein)
NMLFEMLE_00453 3.4e-09
NMLFEMLE_00454 1.1e-205 gntP EG COG2610 H gluconate symporter and related permeases
NMLFEMLE_00455 1.8e-63 yodA S tautomerase
NMLFEMLE_00456 4.4e-55 yodB K transcriptional
NMLFEMLE_00457 4.8e-108 yodC C nitroreductase
NMLFEMLE_00458 5.5e-112 mhqD S Carboxylesterase
NMLFEMLE_00459 1.3e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
NMLFEMLE_00460 6.2e-28 S Protein of unknown function (DUF3311)
NMLFEMLE_00461 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMLFEMLE_00462 2.8e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NMLFEMLE_00463 6.3e-128 yodH Q Methyltransferase
NMLFEMLE_00464 5.2e-24 yodI
NMLFEMLE_00465 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NMLFEMLE_00466 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NMLFEMLE_00467 5.3e-09
NMLFEMLE_00468 3.6e-54 yodL S YodL-like
NMLFEMLE_00469 1.7e-105 yodM 3.6.1.27 I Acid phosphatase homologues
NMLFEMLE_00470 2.8e-24 yozD S YozD-like protein
NMLFEMLE_00472 1.6e-123 yodN
NMLFEMLE_00473 1.4e-36 yozE S Belongs to the UPF0346 family
NMLFEMLE_00474 8.3e-47 yokU S YokU-like protein, putative antitoxin
NMLFEMLE_00475 5.1e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
NMLFEMLE_00476 7.9e-154 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NMLFEMLE_00477 3.2e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
NMLFEMLE_00478 8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NMLFEMLE_00479 4.1e-104 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NMLFEMLE_00480 6.7e-08 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NMLFEMLE_00481 8.1e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMLFEMLE_00483 1.6e-143 yiiD K acetyltransferase
NMLFEMLE_00484 1.1e-255 cgeD M maturation of the outermost layer of the spore
NMLFEMLE_00485 3.5e-38 cgeC
NMLFEMLE_00486 1.5e-65 cgeA
NMLFEMLE_00487 3.4e-185 cgeB S Spore maturation protein
NMLFEMLE_00488 1.1e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NMLFEMLE_00489 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
NMLFEMLE_00490 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NMLFEMLE_00491 5.3e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NMLFEMLE_00492 1.6e-70 ypoP K transcriptional
NMLFEMLE_00493 1.1e-218 mepA V MATE efflux family protein
NMLFEMLE_00494 5.5e-29 ypmT S Uncharacterized ympT
NMLFEMLE_00495 9.4e-80 ypmS S protein conserved in bacteria
NMLFEMLE_00496 1.9e-07 ypmS S protein conserved in bacteria
NMLFEMLE_00497 1.6e-137 ypmR E GDSL-like Lipase/Acylhydrolase
NMLFEMLE_00498 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NMLFEMLE_00499 3.4e-39 ypmP S Protein of unknown function (DUF2535)
NMLFEMLE_00500 2.8e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NMLFEMLE_00501 1.6e-185 pspF K Transcriptional regulator
NMLFEMLE_00502 4.2e-110 hlyIII S protein, Hemolysin III
NMLFEMLE_00503 1.2e-109 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NMLFEMLE_00504 4.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NMLFEMLE_00505 1e-153 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NMLFEMLE_00506 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NMLFEMLE_00507 8.6e-113 ypjP S YpjP-like protein
NMLFEMLE_00508 5.9e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NMLFEMLE_00509 1.7e-75 yphP S Belongs to the UPF0403 family
NMLFEMLE_00510 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NMLFEMLE_00511 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
NMLFEMLE_00512 2.7e-80 ypgQ S phosphohydrolase
NMLFEMLE_00513 6.8e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NMLFEMLE_00514 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NMLFEMLE_00515 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NMLFEMLE_00516 7.9e-31 cspD K Cold-shock protein
NMLFEMLE_00517 3.8e-16 degR
NMLFEMLE_00518 8.1e-31 S Protein of unknown function (DUF2564)
NMLFEMLE_00519 2.6e-27 ypeQ S Zinc-finger
NMLFEMLE_00520 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NMLFEMLE_00521 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NMLFEMLE_00522 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
NMLFEMLE_00524 1.7e-165 polA 2.7.7.7 L 5'3' exonuclease
NMLFEMLE_00525 2e-07
NMLFEMLE_00526 5.5e-37 ypbS S Protein of unknown function (DUF2533)
NMLFEMLE_00527 0.0 ypbR S Dynamin family
NMLFEMLE_00528 1.5e-86 ypbQ S protein conserved in bacteria
NMLFEMLE_00529 8.3e-207 bcsA Q Naringenin-chalcone synthase
NMLFEMLE_00530 5.8e-56 pbuX F xanthine
NMLFEMLE_00531 6.7e-141 pbuX F xanthine
NMLFEMLE_00532 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NMLFEMLE_00533 7.4e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NMLFEMLE_00534 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NMLFEMLE_00535 5e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NMLFEMLE_00536 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NMLFEMLE_00537 4.4e-186 ptxS K transcriptional
NMLFEMLE_00538 1.4e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NMLFEMLE_00539 1.7e-115 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMLFEMLE_00540 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NMLFEMLE_00542 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NMLFEMLE_00543 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NMLFEMLE_00544 2.8e-91 ypsA S Belongs to the UPF0398 family
NMLFEMLE_00545 2.2e-162 yprB L RNase_H superfamily
NMLFEMLE_00546 1e-61 yprB L RNase_H superfamily
NMLFEMLE_00547 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NMLFEMLE_00548 3.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NMLFEMLE_00549 7.3e-71 hspX O Belongs to the small heat shock protein (HSP20) family
NMLFEMLE_00550 1e-47 yppG S YppG-like protein
NMLFEMLE_00552 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
NMLFEMLE_00555 2e-185 yppC S Protein of unknown function (DUF2515)
NMLFEMLE_00556 1e-113 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NMLFEMLE_00557 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NMLFEMLE_00558 8.8e-92 ypoC
NMLFEMLE_00559 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NMLFEMLE_00560 1.1e-127 dnaD L DNA replication protein DnaD
NMLFEMLE_00561 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NMLFEMLE_00562 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NMLFEMLE_00563 3.4e-80 ypmB S protein conserved in bacteria
NMLFEMLE_00564 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NMLFEMLE_00565 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NMLFEMLE_00566 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NMLFEMLE_00567 8e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NMLFEMLE_00568 9.2e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NMLFEMLE_00569 2.5e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NMLFEMLE_00570 3.1e-198 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NMLFEMLE_00572 7.7e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NMLFEMLE_00573 4.1e-129 bshB1 S proteins, LmbE homologs
NMLFEMLE_00574 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NMLFEMLE_00575 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NMLFEMLE_00576 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NMLFEMLE_00577 1.8e-142 ypjB S sporulation protein
NMLFEMLE_00578 7.6e-98 ypjA S membrane
NMLFEMLE_00579 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NMLFEMLE_00580 3.8e-87 petB C COG1290 Cytochrome b subunit of the bc complex
NMLFEMLE_00581 3e-21 petB C COG1290 Cytochrome b subunit of the bc complex
NMLFEMLE_00582 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NMLFEMLE_00583 4.2e-77 ypiF S Protein of unknown function (DUF2487)
NMLFEMLE_00584 2.8e-99 ypiB S Belongs to the UPF0302 family
NMLFEMLE_00585 5.9e-233 S COG0457 FOG TPR repeat
NMLFEMLE_00586 1.1e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NMLFEMLE_00587 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NMLFEMLE_00588 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NMLFEMLE_00589 4.7e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NMLFEMLE_00590 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NMLFEMLE_00591 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NMLFEMLE_00592 4.3e-114 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NMLFEMLE_00593 3.9e-148 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NMLFEMLE_00594 5e-18 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NMLFEMLE_00595 1.5e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NMLFEMLE_00596 3e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NMLFEMLE_00597 2.2e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NMLFEMLE_00598 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NMLFEMLE_00599 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NMLFEMLE_00600 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NMLFEMLE_00601 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NMLFEMLE_00602 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NMLFEMLE_00603 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NMLFEMLE_00604 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NMLFEMLE_00605 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NMLFEMLE_00606 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NMLFEMLE_00607 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NMLFEMLE_00608 3.8e-122 yphF
NMLFEMLE_00609 1.6e-18 yphE S Protein of unknown function (DUF2768)
NMLFEMLE_00610 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NMLFEMLE_00611 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NMLFEMLE_00612 7.9e-28 ypzH
NMLFEMLE_00613 2.5e-161 seaA S YIEGIA protein
NMLFEMLE_00614 1.3e-102 yphA
NMLFEMLE_00615 1e-07 S YpzI-like protein
NMLFEMLE_00616 3.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NMLFEMLE_00617 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NMLFEMLE_00618 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NMLFEMLE_00619 1.8e-23 S Family of unknown function (DUF5359)
NMLFEMLE_00620 2e-112 ypfA M Flagellar protein YcgR
NMLFEMLE_00621 1.1e-104 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NMLFEMLE_00622 6.5e-134 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NMLFEMLE_00623 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NMLFEMLE_00624 1.3e-114 prsW S Involved in the degradation of specific anti-sigma factors
NMLFEMLE_00625 3.1e-166 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NMLFEMLE_00626 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NMLFEMLE_00627 4.5e-103 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NMLFEMLE_00628 2.6e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
NMLFEMLE_00629 2.8e-81 ypbF S Protein of unknown function (DUF2663)
NMLFEMLE_00630 1.3e-75 ypbE M Lysin motif
NMLFEMLE_00631 1.1e-99 ypbD S metal-dependent membrane protease
NMLFEMLE_00632 5.5e-236 recQ 3.6.4.12 L DNA helicase
NMLFEMLE_00633 2.5e-37 recQ 3.6.4.12 L DNA helicase
NMLFEMLE_00634 1.2e-100 ypbB 5.1.3.1 S protein conserved in bacteria
NMLFEMLE_00635 3.3e-69 ypbB 5.1.3.1 S protein conserved in bacteria
NMLFEMLE_00636 4.7e-41 fer C Ferredoxin
NMLFEMLE_00637 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NMLFEMLE_00638 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMLFEMLE_00639 1e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NMLFEMLE_00640 1.2e-192 rsiX
NMLFEMLE_00641 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NMLFEMLE_00642 0.0 resE 2.7.13.3 T Histidine kinase
NMLFEMLE_00643 1.2e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMLFEMLE_00644 6.7e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NMLFEMLE_00645 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NMLFEMLE_00646 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NMLFEMLE_00647 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NMLFEMLE_00648 1.9e-87 spmB S Spore maturation protein
NMLFEMLE_00649 3.5e-103 spmA S Spore maturation protein
NMLFEMLE_00650 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NMLFEMLE_00651 7.6e-97 ypuI S Protein of unknown function (DUF3907)
NMLFEMLE_00652 1.3e-124 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NMLFEMLE_00653 1.4e-92 ypuF S Domain of unknown function (DUF309)
NMLFEMLE_00654 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMLFEMLE_00655 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NMLFEMLE_00656 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NMLFEMLE_00657 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
NMLFEMLE_00658 2.9e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NMLFEMLE_00659 7.8e-55 ypuD
NMLFEMLE_00660 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NMLFEMLE_00661 2.5e-32 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NMLFEMLE_00663 1.9e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMLFEMLE_00664 5.9e-36 S Pfam Transposase IS66
NMLFEMLE_00669 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMLFEMLE_00670 8.1e-149 ypuA S Secreted protein
NMLFEMLE_00671 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NMLFEMLE_00672 1.4e-273 spoVAF EG Stage V sporulation protein AF
NMLFEMLE_00673 1.4e-110 spoVAEA S stage V sporulation protein
NMLFEMLE_00674 2.2e-57 spoVAEB S stage V sporulation protein
NMLFEMLE_00675 9e-192 spoVAD I Stage V sporulation protein AD
NMLFEMLE_00676 2.3e-78 spoVAC S stage V sporulation protein AC
NMLFEMLE_00677 1e-67 spoVAB S Stage V sporulation protein AB
NMLFEMLE_00678 9.6e-112 spoVAA S Stage V sporulation protein AA
NMLFEMLE_00679 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMLFEMLE_00680 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NMLFEMLE_00681 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NMLFEMLE_00682 6.3e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NMLFEMLE_00683 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NMLFEMLE_00684 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NMLFEMLE_00685 2.6e-166 xerD L recombinase XerD
NMLFEMLE_00686 1.4e-36 S Protein of unknown function (DUF4227)
NMLFEMLE_00687 3.2e-77 fur P Belongs to the Fur family
NMLFEMLE_00688 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NMLFEMLE_00689 2.2e-31 yqkK
NMLFEMLE_00690 1.4e-220 mleA 1.1.1.38 C malic enzyme
NMLFEMLE_00691 1.4e-09 mleA 1.1.1.38 C malic enzyme
NMLFEMLE_00692 4.9e-30 mleN C Na H antiporter
NMLFEMLE_00693 1.4e-194 mleN C Na H antiporter
NMLFEMLE_00694 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NMLFEMLE_00695 2.3e-184 ansA 3.5.1.1 EJ L-asparaginase
NMLFEMLE_00696 4.5e-58 ansR K Transcriptional regulator
NMLFEMLE_00697 2.5e-158 yqxK 3.6.4.12 L DNA helicase
NMLFEMLE_00698 1.2e-34 yqxK 3.6.4.12 L DNA helicase
NMLFEMLE_00699 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NMLFEMLE_00701 6.3e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NMLFEMLE_00702 3.1e-12 yqkE S Protein of unknown function (DUF3886)
NMLFEMLE_00703 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NMLFEMLE_00704 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NMLFEMLE_00705 2.8e-54 yqkB S Belongs to the HesB IscA family
NMLFEMLE_00706 7.5e-194 yqkA K GrpB protein
NMLFEMLE_00707 4e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NMLFEMLE_00708 1.8e-86 yqjY K acetyltransferase
NMLFEMLE_00709 9.8e-50 S YolD-like protein
NMLFEMLE_00710 1.6e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMLFEMLE_00712 9e-226 yqjV G Major Facilitator Superfamily
NMLFEMLE_00714 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMLFEMLE_00715 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
NMLFEMLE_00716 7.9e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NMLFEMLE_00717 5e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NMLFEMLE_00718 1.8e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NMLFEMLE_00719 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMLFEMLE_00720 0.0 rocB E arginine degradation protein
NMLFEMLE_00721 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NMLFEMLE_00722 3.6e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMLFEMLE_00723 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NMLFEMLE_00724 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NMLFEMLE_00725 1.4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NMLFEMLE_00726 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NMLFEMLE_00727 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMLFEMLE_00728 4.5e-24 yqzJ
NMLFEMLE_00729 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMLFEMLE_00730 8.9e-141 yqjF S Uncharacterized conserved protein (COG2071)
NMLFEMLE_00731 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NMLFEMLE_00732 4.1e-104 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NMLFEMLE_00733 3.2e-162 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NMLFEMLE_00734 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NMLFEMLE_00736 1.4e-98 yqjB S protein conserved in bacteria
NMLFEMLE_00737 3.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
NMLFEMLE_00738 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NMLFEMLE_00739 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NMLFEMLE_00740 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
NMLFEMLE_00741 9.3e-77 yqiW S Belongs to the UPF0403 family
NMLFEMLE_00742 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NMLFEMLE_00743 7.9e-208 norA EGP Major facilitator Superfamily
NMLFEMLE_00744 2.4e-142 bmrR K helix_turn_helix, mercury resistance
NMLFEMLE_00745 3e-60 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMLFEMLE_00746 2.3e-138 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMLFEMLE_00747 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMLFEMLE_00748 7.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NMLFEMLE_00749 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NMLFEMLE_00750 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NMLFEMLE_00751 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NMLFEMLE_00752 3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NMLFEMLE_00753 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NMLFEMLE_00754 4e-34 yqzF S Protein of unknown function (DUF2627)
NMLFEMLE_00755 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NMLFEMLE_00756 2.2e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NMLFEMLE_00757 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NMLFEMLE_00758 1.8e-212 mmgC I acyl-CoA dehydrogenase
NMLFEMLE_00759 1e-156 hbdA 1.1.1.157 I Dehydrogenase
NMLFEMLE_00760 2.6e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
NMLFEMLE_00761 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NMLFEMLE_00762 1.7e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NMLFEMLE_00763 5.9e-27
NMLFEMLE_00764 2.8e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NMLFEMLE_00766 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NMLFEMLE_00767 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
NMLFEMLE_00768 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
NMLFEMLE_00769 1.7e-78 argR K Regulates arginine biosynthesis genes
NMLFEMLE_00770 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NMLFEMLE_00771 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NMLFEMLE_00772 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NMLFEMLE_00773 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMLFEMLE_00774 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMLFEMLE_00775 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NMLFEMLE_00776 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NMLFEMLE_00777 2.1e-67 yqhY S protein conserved in bacteria
NMLFEMLE_00778 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NMLFEMLE_00779 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NMLFEMLE_00780 3.1e-84 spoIIIAH S SpoIIIAH-like protein
NMLFEMLE_00781 5e-109 spoIIIAG S stage III sporulation protein AG
NMLFEMLE_00782 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NMLFEMLE_00783 1.3e-197 spoIIIAE S stage III sporulation protein AE
NMLFEMLE_00784 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NMLFEMLE_00785 7.6e-29 spoIIIAC S stage III sporulation protein AC
NMLFEMLE_00786 3.2e-84 spoIIIAB S Stage III sporulation protein
NMLFEMLE_00787 6.8e-170 spoIIIAA S stage III sporulation protein AA
NMLFEMLE_00788 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NMLFEMLE_00789 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NMLFEMLE_00790 5.7e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NMLFEMLE_00791 1.7e-74 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NMLFEMLE_00792 2.3e-93 yqhR S Conserved membrane protein YqhR
NMLFEMLE_00793 3e-173 yqhQ S Protein of unknown function (DUF1385)
NMLFEMLE_00794 2.2e-61 yqhP
NMLFEMLE_00795 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
NMLFEMLE_00796 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NMLFEMLE_00797 1.4e-95 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NMLFEMLE_00798 6.6e-14 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NMLFEMLE_00799 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
NMLFEMLE_00800 1.4e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NMLFEMLE_00801 4.9e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NMLFEMLE_00802 5.3e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NMLFEMLE_00803 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NMLFEMLE_00804 3.2e-152 yqhG S Bacterial protein YqhG of unknown function
NMLFEMLE_00805 1.2e-24 sinI S Anti-repressor SinI
NMLFEMLE_00806 1e-54 sinR K transcriptional
NMLFEMLE_00807 4.3e-141 tasA S Cell division protein FtsN
NMLFEMLE_00808 2.5e-58 sipW 3.4.21.89 U Signal peptidase
NMLFEMLE_00809 9e-112 yqxM
NMLFEMLE_00810 7.3e-54 yqzG S Protein of unknown function (DUF3889)
NMLFEMLE_00811 5.2e-26 yqzE S YqzE-like protein
NMLFEMLE_00812 2.6e-43 S ComG operon protein 7
NMLFEMLE_00813 3.9e-44 comGF U Putative Competence protein ComGF
NMLFEMLE_00814 7.6e-58 comGE
NMLFEMLE_00815 1.2e-68 gspH NU protein transport across the cell outer membrane
NMLFEMLE_00816 1.4e-47 comGC U Required for transformation and DNA binding
NMLFEMLE_00817 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
NMLFEMLE_00818 1.1e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NMLFEMLE_00820 7.2e-175 corA P Mg2 transporter protein
NMLFEMLE_00821 4.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NMLFEMLE_00822 3.2e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMLFEMLE_00824 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NMLFEMLE_00825 1.8e-37 yqgY S Protein of unknown function (DUF2626)
NMLFEMLE_00826 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NMLFEMLE_00827 8.9e-23 yqgW S Protein of unknown function (DUF2759)
NMLFEMLE_00828 1.5e-49 yqgV S Thiamine-binding protein
NMLFEMLE_00829 7.4e-197 yqgU
NMLFEMLE_00830 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NMLFEMLE_00831 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMLFEMLE_00832 3.4e-180 glcK 2.7.1.2 G Glucokinase
NMLFEMLE_00833 3.1e-33 yqgQ S Protein conserved in bacteria
NMLFEMLE_00834 2.8e-261 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NMLFEMLE_00835 2.5e-09 yqgO
NMLFEMLE_00836 5.1e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NMLFEMLE_00837 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NMLFEMLE_00838 1.1e-200 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NMLFEMLE_00840 9.2e-51 yqzD
NMLFEMLE_00841 2.1e-71 yqzC S YceG-like family
NMLFEMLE_00842 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMLFEMLE_00843 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMLFEMLE_00844 4.4e-158 pstA P Phosphate transport system permease
NMLFEMLE_00845 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NMLFEMLE_00846 2.4e-150 pstS P Phosphate
NMLFEMLE_00847 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NMLFEMLE_00848 4.3e-231 yqgE EGP Major facilitator superfamily
NMLFEMLE_00849 1.8e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NMLFEMLE_00850 4e-73 yqgC S protein conserved in bacteria
NMLFEMLE_00851 5.6e-130 yqgB S Protein of unknown function (DUF1189)
NMLFEMLE_00852 8.9e-47 yqfZ M LysM domain
NMLFEMLE_00853 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NMLFEMLE_00854 2.8e-61 yqfX S membrane
NMLFEMLE_00855 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NMLFEMLE_00856 4.2e-77 zur P Belongs to the Fur family
NMLFEMLE_00857 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NMLFEMLE_00858 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NMLFEMLE_00859 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NMLFEMLE_00860 1.9e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NMLFEMLE_00861 1.6e-12 yqfQ S YqfQ-like protein
NMLFEMLE_00862 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NMLFEMLE_00863 5.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NMLFEMLE_00864 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
NMLFEMLE_00865 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NMLFEMLE_00866 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NMLFEMLE_00867 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NMLFEMLE_00868 1.7e-87 yaiI S Belongs to the UPF0178 family
NMLFEMLE_00869 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NMLFEMLE_00870 4.5e-112 ccpN K CBS domain
NMLFEMLE_00871 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NMLFEMLE_00872 5.8e-64 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NMLFEMLE_00873 2.1e-84 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NMLFEMLE_00874 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
NMLFEMLE_00875 8.4e-19 S YqzL-like protein
NMLFEMLE_00876 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NMLFEMLE_00877 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NMLFEMLE_00878 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NMLFEMLE_00879 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NMLFEMLE_00880 0.0 yqfF S membrane-associated HD superfamily hydrolase
NMLFEMLE_00882 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
NMLFEMLE_00883 7e-24 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NMLFEMLE_00884 1e-151 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NMLFEMLE_00885 2.7e-45 yqfC S sporulation protein YqfC
NMLFEMLE_00886 2.4e-21 yqfB
NMLFEMLE_00887 4.3e-122 yqfA S UPF0365 protein
NMLFEMLE_00888 3e-182 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NMLFEMLE_00889 4.9e-30 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NMLFEMLE_00890 2.5e-61 yqeY S Yqey-like protein
NMLFEMLE_00891 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NMLFEMLE_00892 8.2e-158 yqeW P COG1283 Na phosphate symporter
NMLFEMLE_00893 1.8e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NMLFEMLE_00894 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NMLFEMLE_00895 5.4e-175 prmA J Methylates ribosomal protein L11
NMLFEMLE_00896 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NMLFEMLE_00897 0.0 dnaK O Heat shock 70 kDa protein
NMLFEMLE_00898 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NMLFEMLE_00899 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NMLFEMLE_00900 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
NMLFEMLE_00901 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NMLFEMLE_00902 7.2e-53 yqxA S Protein of unknown function (DUF3679)
NMLFEMLE_00903 1.5e-222 spoIIP M stage II sporulation protein P
NMLFEMLE_00904 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NMLFEMLE_00905 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NMLFEMLE_00906 2e-141 holA 2.7.7.7 L DNA polymerase III delta subunit
NMLFEMLE_00907 8.2e-35 holA 2.7.7.7 L DNA polymerase III delta subunit
NMLFEMLE_00908 4.1e-15 S YqzM-like protein
NMLFEMLE_00909 1.1e-121 comEC S Competence protein ComEC
NMLFEMLE_00910 1.7e-280 comEC S Competence protein ComEC
NMLFEMLE_00911 1.8e-104 comEB 3.5.4.12 F ComE operon protein 2
NMLFEMLE_00912 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NMLFEMLE_00913 5.1e-145 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMLFEMLE_00914 1.2e-137 yqeM Q Methyltransferase
NMLFEMLE_00915 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NMLFEMLE_00916 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NMLFEMLE_00917 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NMLFEMLE_00918 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NMLFEMLE_00919 2.3e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NMLFEMLE_00920 1.2e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NMLFEMLE_00921 5.3e-95 yqeG S hydrolase of the HAD superfamily
NMLFEMLE_00923 1.2e-140 yqeF E GDSL-like Lipase/Acylhydrolase
NMLFEMLE_00924 9.2e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMLFEMLE_00925 1.2e-104 yqeD S SNARE associated Golgi protein
NMLFEMLE_00926 1.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NMLFEMLE_00927 2.3e-133 yqeB
NMLFEMLE_00928 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
NMLFEMLE_00929 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMLFEMLE_00930 9.3e-278 cisA2 L Recombinase
NMLFEMLE_00931 9.7e-45 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
NMLFEMLE_00932 1.3e-15 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
NMLFEMLE_00933 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
NMLFEMLE_00934 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMLFEMLE_00935 1.6e-54 arsR K ArsR family transcriptional regulator
NMLFEMLE_00936 1.1e-152 yqcI S YqcI/YcgG family
NMLFEMLE_00937 2.8e-23 S YtkA-like
NMLFEMLE_00938 5.5e-50 piuB S PepSY-associated TM region
NMLFEMLE_00939 1.3e-62 piuB S PepSY-associated TM region
NMLFEMLE_00940 2e-38 piuB S PepSY-associated TM region
NMLFEMLE_00941 2.7e-63 K BetI-type transcriptional repressor, C-terminal
NMLFEMLE_00942 5.1e-139 yhfP 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
NMLFEMLE_00943 1.2e-43
NMLFEMLE_00945 1.5e-17 S Protein of unknown function (DUF3992)
NMLFEMLE_00946 5.1e-42 S Spore coat protein Z
NMLFEMLE_00947 4.7e-64 S response regulator aspartate phosphatase
NMLFEMLE_00949 1.7e-27
NMLFEMLE_00950 3.3e-273 A Pre-toxin TG
NMLFEMLE_00951 5.3e-104 S Suppressor of fused protein (SUFU)
NMLFEMLE_00953 5e-60
NMLFEMLE_00955 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NMLFEMLE_00956 2.6e-68 S Bacteriophage holin family
NMLFEMLE_00957 1.6e-146 xepA
NMLFEMLE_00958 1.3e-23
NMLFEMLE_00959 4.1e-56 xkdW S XkdW protein
NMLFEMLE_00960 2e-221
NMLFEMLE_00961 9.6e-40
NMLFEMLE_00962 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NMLFEMLE_00963 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NMLFEMLE_00964 9.6e-71 xkdS S Protein of unknown function (DUF2634)
NMLFEMLE_00965 1.8e-38 xkdR S Protein of unknown function (DUF2577)
NMLFEMLE_00966 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
NMLFEMLE_00967 9e-114 xkdP S Lysin motif
NMLFEMLE_00968 0.0 xkdO L Transglycosylase SLT domain
NMLFEMLE_00969 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
NMLFEMLE_00971 3.9e-75 xkdM S Phage tail tube protein
NMLFEMLE_00972 7.4e-253 xkdK S Phage tail sheath C-terminal domain
NMLFEMLE_00973 4.6e-25
NMLFEMLE_00974 6.6e-75
NMLFEMLE_00975 5.6e-86 S Bacteriophage HK97-gp10, putative tail-component
NMLFEMLE_00976 6.3e-63 yqbH S Domain of unknown function (DUF3599)
NMLFEMLE_00977 4.6e-67 S Protein of unknown function (DUF3199)
NMLFEMLE_00978 6.7e-45 S YqbF, hypothetical protein domain
NMLFEMLE_00979 4.6e-166 xkdG S Phage capsid family
NMLFEMLE_00980 8.8e-120 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NMLFEMLE_00982 1.4e-151 S Phage Mu protein F like protein
NMLFEMLE_00983 6.3e-290 yqbA S portal protein
NMLFEMLE_00984 2.1e-246 S phage terminase, large subunit
NMLFEMLE_00985 3e-101 yqaS L DNA packaging
NMLFEMLE_00988 2.5e-40 L Transposase
NMLFEMLE_00989 8.3e-13 L Transposase
NMLFEMLE_00990 3.5e-19 dcm 2.1.1.37 L C-5 cytosine-specific DNA methylase
NMLFEMLE_00991 1.5e-106 dcm 2.1.1.37 L C-5 cytosine-specific DNA methylase
NMLFEMLE_00992 4.3e-110 L SacI restriction endonuclease
NMLFEMLE_00993 2.4e-30 yqaO S Phage-like element PBSX protein XtrA
NMLFEMLE_00994 9.7e-71 rusA L Endodeoxyribonuclease RusA
NMLFEMLE_00996 2.2e-162 xkdC L IstB-like ATP binding protein
NMLFEMLE_00997 9.8e-121 3.1.3.16 L DnaD domain protein
NMLFEMLE_00998 1.2e-149 recT L RecT family
NMLFEMLE_00999 3.7e-71 yqaJ L YqaJ-like viral recombinase domain
NMLFEMLE_01000 2.3e-68 yqaJ L YqaJ-like viral recombinase domain
NMLFEMLE_01004 4.4e-103
NMLFEMLE_01006 6.5e-37 K Helix-turn-helix XRE-family like proteins
NMLFEMLE_01007 1.1e-56 K sequence-specific DNA binding
NMLFEMLE_01009 1e-101 adk 2.7.4.3 F adenylate kinase activity
NMLFEMLE_01010 4.4e-94 yqaB E IrrE N-terminal-like domain
NMLFEMLE_01011 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMLFEMLE_01012 3.3e-113 tetR3 K Transcriptional regulator
NMLFEMLE_01013 1.1e-216 mepA V Multidrug transporter MatE
NMLFEMLE_01014 6e-165 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NMLFEMLE_01015 5e-162 yrkH P Rhodanese Homology Domain
NMLFEMLE_01016 1.8e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
NMLFEMLE_01017 1.2e-49 yrkE O DsrE/DsrF/DrsH-like family
NMLFEMLE_01018 2.6e-17 yrkE O DsrE/DsrF/DrsH-like family
NMLFEMLE_01019 7.8e-39 yrkD S protein conserved in bacteria
NMLFEMLE_01020 1.4e-106 yrkC G Cupin domain
NMLFEMLE_01021 3.1e-150 bltR K helix_turn_helix, mercury resistance
NMLFEMLE_01022 3.3e-209 blt EGP Major facilitator Superfamily
NMLFEMLE_01023 5.9e-82 bltD 2.3.1.57 K FR47-like protein
NMLFEMLE_01024 5.1e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NMLFEMLE_01025 3.9e-16 S YrzO-like protein
NMLFEMLE_01026 1.4e-170 yrdR EG EamA-like transporter family
NMLFEMLE_01027 1e-159 yrdQ K Transcriptional regulator
NMLFEMLE_01028 1.5e-104 trkA P Oxidoreductase
NMLFEMLE_01029 4e-149 czcD P COG1230 Co Zn Cd efflux system component
NMLFEMLE_01030 2.4e-62 yodA S tautomerase
NMLFEMLE_01031 3.8e-162 gltR K LysR substrate binding domain
NMLFEMLE_01032 2.5e-226 brnQ E Component of the transport system for branched-chain amino acids
NMLFEMLE_01033 3.8e-44 azlD E Branched-chain amino acid transport protein (AzlD)
NMLFEMLE_01034 6e-64 azlC E AzlC protein
NMLFEMLE_01035 1.1e-57 azlC E AzlC protein
NMLFEMLE_01036 6.3e-79 bkdR K helix_turn_helix ASNC type
NMLFEMLE_01037 1.2e-15 yrdF K ribonuclease inhibitor
NMLFEMLE_01038 9.2e-231 cypA C Cytochrome P450
NMLFEMLE_01039 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
NMLFEMLE_01040 5.7e-54 S Protein of unknown function (DUF2568)
NMLFEMLE_01041 6.4e-90 yrdA S DinB family
NMLFEMLE_01042 3.5e-165 aadK G Streptomycin adenylyltransferase
NMLFEMLE_01043 1.8e-113 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NMLFEMLE_01044 1.7e-69 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NMLFEMLE_01046 4.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NMLFEMLE_01047 1.6e-123 yrpD S Domain of unknown function, YrpD
NMLFEMLE_01048 1.5e-100 K helix_turn_helix gluconate operon transcriptional repressor
NMLFEMLE_01050 2.8e-209 rbtT P Major Facilitator Superfamily
NMLFEMLE_01051 4.3e-114 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMLFEMLE_01052 7e-154 2.2.1.1 G Transketolase, pyrimidine binding domain
NMLFEMLE_01053 6.4e-135 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
NMLFEMLE_01054 5.6e-98 flr S Flavin reductase like domain
NMLFEMLE_01055 7.2e-118 bmrR K helix_turn_helix, mercury resistance
NMLFEMLE_01056 2.2e-47 yjbR S YjbR
NMLFEMLE_01057 2e-92 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NMLFEMLE_01058 1.2e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NMLFEMLE_01059 3.8e-187 yrpG C Aldo/keto reductase family
NMLFEMLE_01060 4e-224 yraO C Citrate transporter
NMLFEMLE_01061 3.7e-162 yraN K Transcriptional regulator
NMLFEMLE_01062 7e-45 yraM S PrpF protein
NMLFEMLE_01063 2.6e-135 yraM S PrpF protein
NMLFEMLE_01064 1.5e-149 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NMLFEMLE_01065 2.1e-39 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMLFEMLE_01066 4.9e-148 S Alpha beta hydrolase
NMLFEMLE_01067 1.7e-60 T sh3 domain protein
NMLFEMLE_01068 2.4e-61 T sh3 domain protein
NMLFEMLE_01070 3.8e-66 E Glyoxalase-like domain
NMLFEMLE_01071 1.5e-36 yraG
NMLFEMLE_01072 6.4e-63 yraF M Spore coat protein
NMLFEMLE_01073 3.8e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NMLFEMLE_01074 7.5e-26 yraE
NMLFEMLE_01075 1.1e-49 yraD M Spore coat protein
NMLFEMLE_01076 1.6e-46 yraB K helix_turn_helix, mercury resistance
NMLFEMLE_01077 1.6e-28 yphJ 4.1.1.44 S peroxiredoxin activity
NMLFEMLE_01078 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
NMLFEMLE_01079 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
NMLFEMLE_01080 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NMLFEMLE_01081 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NMLFEMLE_01082 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NMLFEMLE_01083 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NMLFEMLE_01084 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
NMLFEMLE_01085 0.0 levR K PTS system fructose IIA component
NMLFEMLE_01086 3.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NMLFEMLE_01087 3.6e-106 yrhP E LysE type translocator
NMLFEMLE_01088 3.1e-150 yrhO K Archaeal transcriptional regulator TrmB
NMLFEMLE_01089 3.1e-37 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NMLFEMLE_01090 1.3e-148 rsiV S Protein of unknown function (DUF3298)
NMLFEMLE_01091 5.5e-77 yrhL I Acyltransferase family
NMLFEMLE_01092 2.4e-227 yrhL I Acyltransferase family
NMLFEMLE_01093 3.2e-17 yrhK S YrhK-like protein
NMLFEMLE_01094 7.3e-29 S Butirosin biosynthesis protein H, N-terminal
NMLFEMLE_01095 3.9e-11 O Butirosin biosynthesis protein H, N-terminal
NMLFEMLE_01096 1.5e-52 S dehydrogenases and related proteins
NMLFEMLE_01097 6.6e-88 yodQ 3.5.1.16 E Acetylornithine deacetylase
NMLFEMLE_01098 2.6e-100 EF ATP-grasp domain
NMLFEMLE_01099 6.6e-181 hutH 4.3.1.23, 4.3.1.24, 4.3.1.3, 5.4.3.6 E Aromatic amino acid lyase
NMLFEMLE_01100 2e-46 hopR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NMLFEMLE_01101 7.2e-104 Q TIGRFAM amino acid adenylation domain
NMLFEMLE_01102 1.1e-62 S ABC-2 family transporter protein
NMLFEMLE_01103 3.3e-19 S ABC-2 family transporter protein
NMLFEMLE_01104 9.4e-117 S ATPases associated with a variety of cellular activities
NMLFEMLE_01105 2.6e-119 wbpP 5.1.3.2, 5.1.3.7 GM NmrA-like family
NMLFEMLE_01106 4.3e-168 capL C PFAM UDP-glucose GDP-mannose dehydrogenase
NMLFEMLE_01107 3.2e-234 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NMLFEMLE_01108 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NMLFEMLE_01109 3.3e-101 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NMLFEMLE_01110 7.2e-95 yrhH Q methyltransferase
NMLFEMLE_01113 1.8e-142 focA P Formate nitrite
NMLFEMLE_01114 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
NMLFEMLE_01115 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NMLFEMLE_01116 2.4e-78 yrhD S Protein of unknown function (DUF1641)
NMLFEMLE_01117 4.6e-35 yrhC S YrhC-like protein
NMLFEMLE_01118 1.3e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NMLFEMLE_01119 1.5e-141 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NMLFEMLE_01120 2.3e-14 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NMLFEMLE_01121 2.7e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NMLFEMLE_01122 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NMLFEMLE_01123 1e-25 yrzA S Protein of unknown function (DUF2536)
NMLFEMLE_01124 9.7e-60 yrrS S Protein of unknown function (DUF1510)
NMLFEMLE_01125 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NMLFEMLE_01126 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NMLFEMLE_01127 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NMLFEMLE_01128 2.7e-246 yegQ O COG0826 Collagenase and related proteases
NMLFEMLE_01129 2.9e-173 yegQ O Peptidase U32
NMLFEMLE_01130 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
NMLFEMLE_01131 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NMLFEMLE_01132 2.7e-32 yrzB S Belongs to the UPF0473 family
NMLFEMLE_01133 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NMLFEMLE_01134 1.7e-41 yrzL S Belongs to the UPF0297 family
NMLFEMLE_01135 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NMLFEMLE_01136 6e-162 yrrI S AI-2E family transporter
NMLFEMLE_01137 5.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NMLFEMLE_01138 4.8e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
NMLFEMLE_01139 4e-108 gluC P ABC transporter
NMLFEMLE_01140 6.4e-106 glnP P ABC transporter
NMLFEMLE_01141 8e-08 S Protein of unknown function (DUF3918)
NMLFEMLE_01142 9.8e-31 yrzR
NMLFEMLE_01143 1.2e-82 yrrD S protein conserved in bacteria
NMLFEMLE_01144 1.9e-250 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NMLFEMLE_01145 2.7e-194 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NMLFEMLE_01146 1.4e-15 S COG0457 FOG TPR repeat
NMLFEMLE_01147 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NMLFEMLE_01148 3.3e-211 iscS 2.8.1.7 E Cysteine desulfurase
NMLFEMLE_01149 1.2e-70 cymR K Transcriptional regulator
NMLFEMLE_01150 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NMLFEMLE_01151 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NMLFEMLE_01152 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NMLFEMLE_01153 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NMLFEMLE_01155 9.7e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
NMLFEMLE_01156 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NMLFEMLE_01157 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NMLFEMLE_01158 8.2e-25 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NMLFEMLE_01159 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NMLFEMLE_01160 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NMLFEMLE_01161 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NMLFEMLE_01162 1.1e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NMLFEMLE_01163 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NMLFEMLE_01164 1.6e-48 yrzD S Post-transcriptional regulator
NMLFEMLE_01165 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMLFEMLE_01166 1.7e-111 yrbG S membrane
NMLFEMLE_01167 6.4e-73 yrzE S Protein of unknown function (DUF3792)
NMLFEMLE_01168 1.1e-38 yajC U Preprotein translocase subunit YajC
NMLFEMLE_01169 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NMLFEMLE_01170 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NMLFEMLE_01171 1e-17 yrzS S Protein of unknown function (DUF2905)
NMLFEMLE_01172 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NMLFEMLE_01173 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NMLFEMLE_01174 4.8e-93 bofC S BofC C-terminal domain
NMLFEMLE_01175 2e-252 csbX EGP Major facilitator Superfamily
NMLFEMLE_01176 1.4e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NMLFEMLE_01177 6.5e-119 yrzF T serine threonine protein kinase
NMLFEMLE_01179 4e-51 S Family of unknown function (DUF5412)
NMLFEMLE_01180 5.3e-262 alsT E Sodium alanine symporter
NMLFEMLE_01181 1.6e-126 yebC K transcriptional regulatory protein
NMLFEMLE_01182 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMLFEMLE_01183 9.8e-158 safA M spore coat assembly protein SafA
NMLFEMLE_01184 1.8e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NMLFEMLE_01185 7.3e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NMLFEMLE_01186 7.3e-305 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NMLFEMLE_01187 5e-218 nifS 2.8.1.7 E Cysteine desulfurase
NMLFEMLE_01188 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
NMLFEMLE_01189 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
NMLFEMLE_01190 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NMLFEMLE_01191 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NMLFEMLE_01192 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NMLFEMLE_01193 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NMLFEMLE_01194 8e-28 ysxB J ribosomal protein
NMLFEMLE_01195 1.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
NMLFEMLE_01196 2.7e-160 spoIVFB S Stage IV sporulation protein
NMLFEMLE_01197 1.1e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NMLFEMLE_01198 4.7e-143 minD D Belongs to the ParA family
NMLFEMLE_01199 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NMLFEMLE_01200 1.4e-84 mreD M shape-determining protein
NMLFEMLE_01201 2.8e-157 mreC M Involved in formation and maintenance of cell shape
NMLFEMLE_01202 1.8e-184 mreB D Rod shape-determining protein MreB
NMLFEMLE_01203 5.4e-51 radC E Belongs to the UPF0758 family
NMLFEMLE_01205 2.2e-99
NMLFEMLE_01206 2.2e-23
NMLFEMLE_01207 5.4e-08
NMLFEMLE_01208 4.2e-15 K Helix-turn-helix domain
NMLFEMLE_01211 5.9e-12
NMLFEMLE_01212 1.1e-178 A Pre-toxin TG
NMLFEMLE_01213 8.3e-67 S Immunity protein 70
NMLFEMLE_01214 4.4e-127 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NMLFEMLE_01215 2.1e-57 S Bacteriophage holin family
NMLFEMLE_01216 8.5e-95 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
NMLFEMLE_01218 1.3e-12
NMLFEMLE_01219 6.1e-88
NMLFEMLE_01220 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
NMLFEMLE_01221 3.5e-220 NU Prophage endopeptidase tail
NMLFEMLE_01222 1.7e-111 S Phage tail protein
NMLFEMLE_01223 0.0 D phage tail tape measure protein
NMLFEMLE_01226 3.4e-77 S Phage tail tube protein
NMLFEMLE_01228 3.2e-12 S Bacteriophage HK97-gp10, putative tail-component
NMLFEMLE_01229 1.4e-37 S Phage head-tail joining protein
NMLFEMLE_01230 1.3e-37 S Phage gp6-like head-tail connector protein
NMLFEMLE_01231 4e-21
NMLFEMLE_01232 1.6e-156 gp36 S capsid protein
NMLFEMLE_01233 3.4e-80 S peptidase activity
NMLFEMLE_01234 2.2e-174 S Phage portal protein
NMLFEMLE_01235 2.5e-303 S Terminase
NMLFEMLE_01236 2e-78 L phage terminase small subunit
NMLFEMLE_01237 6.2e-50 V HNH endonuclease
NMLFEMLE_01241 1.5e-59
NMLFEMLE_01244 3.3e-20 S YopX protein
NMLFEMLE_01246 2.1e-80
NMLFEMLE_01247 2.3e-93 S nuclease activity
NMLFEMLE_01248 6.2e-65
NMLFEMLE_01249 0.0 S hydrolase activity
NMLFEMLE_01250 1.5e-74 S Protein of unknown function (DUF669)
NMLFEMLE_01252 7.1e-167 tadZ D AAA domain
NMLFEMLE_01253 1.3e-91 S DNA protection
NMLFEMLE_01255 3.5e-21 S Uncharacterized protein YqaH
NMLFEMLE_01258 8.8e-09 plcR K helix-turn-helix
NMLFEMLE_01259 8.9e-64 S sequence-specific DNA binding
NMLFEMLE_01260 4.5e-71 S Pfam:Peptidase_M78
NMLFEMLE_01261 7.6e-229 S Recombinase
NMLFEMLE_01262 9.8e-68 radC E Belongs to the UPF0758 family
NMLFEMLE_01263 2.8e-102 maf D septum formation protein Maf
NMLFEMLE_01264 3.3e-162 spoIIB S Sporulation related domain
NMLFEMLE_01265 5.5e-41 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NMLFEMLE_01266 1.4e-245 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NMLFEMLE_01267 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NMLFEMLE_01268 1.6e-25
NMLFEMLE_01269 7.8e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NMLFEMLE_01270 6.4e-190 spoVID M stage VI sporulation protein D
NMLFEMLE_01271 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NMLFEMLE_01272 6.2e-182 hemB 4.2.1.24 H Belongs to the ALAD family
NMLFEMLE_01273 7.9e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NMLFEMLE_01274 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NMLFEMLE_01275 3.6e-146 hemX O cytochrome C
NMLFEMLE_01276 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NMLFEMLE_01277 7e-89 ysxD
NMLFEMLE_01278 3.4e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
NMLFEMLE_01280 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NMLFEMLE_01281 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NMLFEMLE_01282 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NMLFEMLE_01283 2.7e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NMLFEMLE_01284 2.3e-187 ysoA H Tetratricopeptide repeat
NMLFEMLE_01285 1.5e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMLFEMLE_01286 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMLFEMLE_01287 3.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NMLFEMLE_01288 2.2e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NMLFEMLE_01289 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NMLFEMLE_01290 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
NMLFEMLE_01291 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NMLFEMLE_01293 4.8e-76 ysnE K acetyltransferase
NMLFEMLE_01294 9.1e-134 ysnF S protein conserved in bacteria
NMLFEMLE_01296 4.1e-92 ysnB S Phosphoesterase
NMLFEMLE_01297 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NMLFEMLE_01298 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NMLFEMLE_01299 6.5e-196 gerM S COG5401 Spore germination protein
NMLFEMLE_01300 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NMLFEMLE_01301 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NMLFEMLE_01302 3.3e-30 gerE K Transcriptional regulator
NMLFEMLE_01303 1.7e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NMLFEMLE_01304 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NMLFEMLE_01305 4.4e-263 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NMLFEMLE_01306 2.4e-107 sdhC C succinate dehydrogenase
NMLFEMLE_01307 1.2e-79 yslB S Protein of unknown function (DUF2507)
NMLFEMLE_01308 5.4e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NMLFEMLE_01309 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NMLFEMLE_01310 2e-52 trxA O Belongs to the thioredoxin family
NMLFEMLE_01311 6.1e-131 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NMLFEMLE_01312 3e-150 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NMLFEMLE_01314 4.2e-178 etfA C Electron transfer flavoprotein
NMLFEMLE_01315 4.5e-135 etfB C Electron transfer flavoprotein
NMLFEMLE_01316 1.2e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NMLFEMLE_01317 2.7e-100 fadR K Transcriptional regulator
NMLFEMLE_01318 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NMLFEMLE_01319 7.3e-68 yshE S membrane
NMLFEMLE_01320 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NMLFEMLE_01321 0.0 polX L COG1796 DNA polymerase IV (family X)
NMLFEMLE_01322 1.3e-85 cvpA S membrane protein, required for colicin V production
NMLFEMLE_01323 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NMLFEMLE_01324 5.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMLFEMLE_01325 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMLFEMLE_01326 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NMLFEMLE_01327 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMLFEMLE_01328 2.6e-32 sspI S Belongs to the SspI family
NMLFEMLE_01329 1e-204 ysfB KT regulator
NMLFEMLE_01330 1.8e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
NMLFEMLE_01331 1.7e-254 glcF C Glycolate oxidase
NMLFEMLE_01332 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
NMLFEMLE_01334 0.0 cstA T Carbon starvation protein
NMLFEMLE_01335 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NMLFEMLE_01336 4.9e-143 araQ G transport system permease
NMLFEMLE_01337 2.7e-166 araP G carbohydrate transport
NMLFEMLE_01338 6.2e-254 araN G carbohydrate transport
NMLFEMLE_01339 1.3e-218 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NMLFEMLE_01340 2.4e-113 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NMLFEMLE_01341 2.7e-21 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NMLFEMLE_01342 2.4e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NMLFEMLE_01343 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NMLFEMLE_01344 2.7e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NMLFEMLE_01345 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NMLFEMLE_01346 6.4e-204 ysdC G COG1363 Cellulase M and related proteins
NMLFEMLE_01347 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NMLFEMLE_01348 7.5e-45 ysdA S Membrane
NMLFEMLE_01349 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NMLFEMLE_01350 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NMLFEMLE_01351 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NMLFEMLE_01353 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NMLFEMLE_01354 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NMLFEMLE_01355 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
NMLFEMLE_01356 0.0 lytS 2.7.13.3 T Histidine kinase
NMLFEMLE_01357 7.3e-149 ysaA S HAD-hyrolase-like
NMLFEMLE_01358 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMLFEMLE_01359 3.8e-159 ytxC S YtxC-like family
NMLFEMLE_01360 4.9e-111 ytxB S SNARE associated Golgi protein
NMLFEMLE_01361 6.6e-173 dnaI L Primosomal protein DnaI
NMLFEMLE_01362 7.7e-266 dnaB L Membrane attachment protein
NMLFEMLE_01363 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NMLFEMLE_01364 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NMLFEMLE_01365 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NMLFEMLE_01366 9.9e-67 ytcD K Transcriptional regulator
NMLFEMLE_01367 7.3e-201 ytbD EGP Major facilitator Superfamily
NMLFEMLE_01368 8.9e-161 ytbE S reductase
NMLFEMLE_01369 4.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NMLFEMLE_01370 1.1e-107 ytaF P Probably functions as a manganese efflux pump
NMLFEMLE_01371 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NMLFEMLE_01372 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NMLFEMLE_01373 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NMLFEMLE_01374 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMLFEMLE_01375 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NMLFEMLE_01376 4.1e-242 icd 1.1.1.42 C isocitrate
NMLFEMLE_01377 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NMLFEMLE_01378 2.3e-70 yeaL S membrane
NMLFEMLE_01379 6.7e-24 ytvI S sporulation integral membrane protein YtvI
NMLFEMLE_01380 1.4e-122 ytvI S sporulation integral membrane protein YtvI
NMLFEMLE_01381 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NMLFEMLE_01382 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NMLFEMLE_01383 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NMLFEMLE_01384 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NMLFEMLE_01385 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NMLFEMLE_01386 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NMLFEMLE_01387 0.0 dnaE 2.7.7.7 L DNA polymerase
NMLFEMLE_01388 6.6e-14 ytrH S Sporulation protein YtrH
NMLFEMLE_01389 1.8e-68 ytrI
NMLFEMLE_01390 9.2e-29
NMLFEMLE_01391 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NMLFEMLE_01392 2.4e-47 ytpI S YtpI-like protein
NMLFEMLE_01393 8e-241 ytoI K transcriptional regulator containing CBS domains
NMLFEMLE_01394 1.4e-156 ytnM S membrane transporter protein
NMLFEMLE_01395 7.3e-236 ytnL 3.5.1.47 E hydrolase activity
NMLFEMLE_01396 3.4e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
NMLFEMLE_01397 4.9e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMLFEMLE_01398 5.4e-46 ytnI O COG0695 Glutaredoxin and related proteins
NMLFEMLE_01399 1.7e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMLFEMLE_01400 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NMLFEMLE_01401 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
NMLFEMLE_01402 1.8e-122 tcyL P Binding-protein-dependent transport system inner membrane component
NMLFEMLE_01403 3.2e-144 tcyK M Bacterial periplasmic substrate-binding proteins
NMLFEMLE_01404 1.2e-117 tcyK ET Bacterial periplasmic substrate-binding proteins
NMLFEMLE_01405 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
NMLFEMLE_01406 1.2e-171 ytlI K LysR substrate binding domain
NMLFEMLE_01407 1.7e-130 ytkL S Belongs to the UPF0173 family
NMLFEMLE_01408 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMLFEMLE_01410 1.2e-266 argH 4.3.2.1 E argininosuccinate lyase
NMLFEMLE_01411 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NMLFEMLE_01412 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NMLFEMLE_01413 4.5e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NMLFEMLE_01414 7e-165 ytxK 2.1.1.72 L DNA methylase
NMLFEMLE_01415 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NMLFEMLE_01416 8.7e-70 ytfJ S Sporulation protein YtfJ
NMLFEMLE_01417 4.7e-115 ytfI S Protein of unknown function (DUF2953)
NMLFEMLE_01418 8.5e-87 yteJ S RDD family
NMLFEMLE_01419 5.1e-179 sppA OU signal peptide peptidase SppA
NMLFEMLE_01420 2.4e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMLFEMLE_01421 0.0 ytcJ S amidohydrolase
NMLFEMLE_01422 2.3e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NMLFEMLE_01423 2e-29 sspB S spore protein
NMLFEMLE_01424 5.1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMLFEMLE_01425 5.9e-208 iscS2 2.8.1.7 E Cysteine desulfurase
NMLFEMLE_01426 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
NMLFEMLE_01427 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NMLFEMLE_01428 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NMLFEMLE_01429 1e-108 yttP K Transcriptional regulator
NMLFEMLE_01430 5.9e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NMLFEMLE_01431 2e-308 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NMLFEMLE_01432 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NMLFEMLE_01434 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NMLFEMLE_01435 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NMLFEMLE_01436 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NMLFEMLE_01437 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
NMLFEMLE_01438 7.7e-156 acuC BQ histone deacetylase
NMLFEMLE_01439 1.4e-33 acuC BQ histone deacetylase
NMLFEMLE_01440 6.8e-125 motS N Flagellar motor protein
NMLFEMLE_01441 1.3e-145 motA N flagellar motor
NMLFEMLE_01442 1.7e-182 ccpA K catabolite control protein A
NMLFEMLE_01443 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NMLFEMLE_01444 4.8e-54 ytxJ O Protein of unknown function (DUF2847)
NMLFEMLE_01445 6.6e-17 ytxH S COG4980 Gas vesicle protein
NMLFEMLE_01446 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NMLFEMLE_01447 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NMLFEMLE_01448 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NMLFEMLE_01449 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMLFEMLE_01450 9.8e-149 ytpQ S Belongs to the UPF0354 family
NMLFEMLE_01451 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NMLFEMLE_01452 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NMLFEMLE_01453 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NMLFEMLE_01454 9.8e-52 ytzB S small secreted protein
NMLFEMLE_01455 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NMLFEMLE_01456 2.7e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NMLFEMLE_01457 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NMLFEMLE_01458 2e-45 ytzH S YtzH-like protein
NMLFEMLE_01459 2.3e-150 ytmP 2.7.1.89 M Phosphotransferase
NMLFEMLE_01460 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NMLFEMLE_01461 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NMLFEMLE_01462 1.3e-165 ytlQ
NMLFEMLE_01463 5.6e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NMLFEMLE_01464 1.9e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NMLFEMLE_01465 2.4e-239 pepV 3.5.1.18 E Dipeptidase
NMLFEMLE_01466 7.6e-164 pbuO S permease
NMLFEMLE_01467 1.3e-49 pbuO S permease
NMLFEMLE_01468 9.3e-201 ythQ U Bacterial ABC transporter protein EcsB
NMLFEMLE_01469 4.8e-131 ythP V ABC transporter
NMLFEMLE_01470 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NMLFEMLE_01471 6.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NMLFEMLE_01472 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMLFEMLE_01473 1.9e-239 ytfP S HI0933-like protein
NMLFEMLE_01474 3.9e-63 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NMLFEMLE_01475 4.7e-194 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NMLFEMLE_01476 3.1e-26 yteV S Sporulation protein Cse60
NMLFEMLE_01477 5.3e-116 yteU S Integral membrane protein
NMLFEMLE_01478 2.3e-23 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NMLFEMLE_01479 1.8e-209 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NMLFEMLE_01480 1.3e-72 yteS G transport
NMLFEMLE_01481 4.5e-114 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NMLFEMLE_01482 4.1e-80 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NMLFEMLE_01483 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NMLFEMLE_01484 0.0 ytdP K Transcriptional regulator
NMLFEMLE_01485 4.4e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NMLFEMLE_01486 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
NMLFEMLE_01487 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NMLFEMLE_01488 5.5e-225 bioI 1.14.14.46 C Cytochrome P450
NMLFEMLE_01489 4.2e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NMLFEMLE_01490 2.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NMLFEMLE_01491 3.3e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NMLFEMLE_01492 1.1e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NMLFEMLE_01493 2.1e-148 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NMLFEMLE_01494 4.1e-172 ytaP S Acetyl xylan esterase (AXE1)
NMLFEMLE_01495 1e-114 msmR K Transcriptional regulator
NMLFEMLE_01496 2.9e-57 msmR K Transcriptional regulator
NMLFEMLE_01497 1.4e-245 msmE G Bacterial extracellular solute-binding protein
NMLFEMLE_01498 6.2e-168 amyD P ABC transporter
NMLFEMLE_01499 9.8e-144 amyC P ABC transporter (permease)
NMLFEMLE_01500 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NMLFEMLE_01501 8.1e-51 ytwF P Sulfurtransferase
NMLFEMLE_01502 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMLFEMLE_01503 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NMLFEMLE_01504 1.5e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NMLFEMLE_01505 3e-210 yttB EGP Major facilitator Superfamily
NMLFEMLE_01506 4.3e-42 yttA 2.7.13.3 S Pfam Transposase IS66
NMLFEMLE_01507 0.0 bceB V ABC transporter (permease)
NMLFEMLE_01508 6.2e-137 bceA V ABC transporter, ATP-binding protein
NMLFEMLE_01509 1.6e-185 T PhoQ Sensor
NMLFEMLE_01510 1.1e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMLFEMLE_01511 3.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NMLFEMLE_01512 9.1e-127 ytrE V ABC transporter, ATP-binding protein
NMLFEMLE_01513 1.3e-147
NMLFEMLE_01514 2.1e-153 P ABC-2 family transporter protein
NMLFEMLE_01515 4.2e-161 ytrB P abc transporter atp-binding protein
NMLFEMLE_01516 5.1e-66 ytrA K GntR family transcriptional regulator
NMLFEMLE_01518 6.7e-41 ytzC S Protein of unknown function (DUF2524)
NMLFEMLE_01519 2.3e-189 yhcC S Fe-S oxidoreductase
NMLFEMLE_01520 2.4e-104 ytqB J Putative rRNA methylase
NMLFEMLE_01521 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NMLFEMLE_01522 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
NMLFEMLE_01523 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NMLFEMLE_01524 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NMLFEMLE_01525 0.0 asnB 6.3.5.4 E Asparagine synthase
NMLFEMLE_01526 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NMLFEMLE_01527 9.7e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NMLFEMLE_01528 2.1e-38 ytmB S Protein of unknown function (DUF2584)
NMLFEMLE_01529 2.7e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NMLFEMLE_01530 4.2e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NMLFEMLE_01531 1.4e-144 ytlC P ABC transporter
NMLFEMLE_01532 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NMLFEMLE_01533 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NMLFEMLE_01534 3.5e-62 ytkC S Bacteriophage holin family
NMLFEMLE_01535 2.1e-76 dps P Belongs to the Dps family
NMLFEMLE_01537 1.1e-72 ytkA S YtkA-like
NMLFEMLE_01538 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NMLFEMLE_01539 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NMLFEMLE_01540 3.6e-41 rpmE2 J Ribosomal protein L31
NMLFEMLE_01541 3.1e-248 cydA 1.10.3.14 C oxidase, subunit
NMLFEMLE_01542 3.6e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NMLFEMLE_01543 1.1e-24 S Domain of Unknown Function (DUF1540)
NMLFEMLE_01544 3.4e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NMLFEMLE_01545 4.8e-97 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NMLFEMLE_01546 5.6e-122 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NMLFEMLE_01547 3.6e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NMLFEMLE_01548 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
NMLFEMLE_01549 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NMLFEMLE_01550 1.7e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NMLFEMLE_01551 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NMLFEMLE_01552 1.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NMLFEMLE_01553 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NMLFEMLE_01554 1.6e-38 menF 5.4.4.2 HQ Isochorismate synthase
NMLFEMLE_01555 2.9e-218 menF 5.4.4.2 HQ Isochorismate synthase
NMLFEMLE_01556 2.6e-132 dksA T COG1734 DnaK suppressor protein
NMLFEMLE_01557 4.6e-129 galU 2.7.7.9 M Nucleotidyl transferase
NMLFEMLE_01558 1.6e-241 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMLFEMLE_01559 2.9e-177 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NMLFEMLE_01560 3.4e-219 ytcC M Glycosyltransferase Family 4
NMLFEMLE_01562 9.7e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
NMLFEMLE_01563 6.9e-217 cotSA M Glycosyl transferases group 1
NMLFEMLE_01564 4.4e-205 cotI S Spore coat protein
NMLFEMLE_01565 9.3e-75 tspO T membrane
NMLFEMLE_01566 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NMLFEMLE_01567 5.8e-285 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NMLFEMLE_01568 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NMLFEMLE_01569 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NMLFEMLE_01570 2.5e-135 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NMLFEMLE_01571 3e-228 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NMLFEMLE_01580 7.8e-08
NMLFEMLE_01588 2e-08
NMLFEMLE_01593 3.4e-39 S COG NOG14552 non supervised orthologous group
NMLFEMLE_01594 1.3e-89 thiT S Thiamine transporter protein (Thia_YuaJ)
NMLFEMLE_01595 2.4e-92 M1-753 M FR47-like protein
NMLFEMLE_01596 4.5e-187 yuaG 3.4.21.72 S protein conserved in bacteria
NMLFEMLE_01597 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NMLFEMLE_01598 8.7e-84 yuaE S DinB superfamily
NMLFEMLE_01599 5.6e-106 yuaD
NMLFEMLE_01600 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
NMLFEMLE_01601 4e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NMLFEMLE_01602 3.6e-94 yuaC K Belongs to the GbsR family
NMLFEMLE_01603 2.2e-91 yuaB
NMLFEMLE_01604 9.6e-104 ktrA P COG0569 K transport systems, NAD-binding component
NMLFEMLE_01605 5.6e-234 ktrB P Potassium
NMLFEMLE_01606 1e-38 yiaA S yiaA/B two helix domain
NMLFEMLE_01607 7.9e-151 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NMLFEMLE_01608 4.5e-217 yubD P Major Facilitator Superfamily
NMLFEMLE_01609 4.9e-49 yubD P Major Facilitator Superfamily
NMLFEMLE_01610 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NMLFEMLE_01612 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NMLFEMLE_01613 3.1e-196 yubA S transporter activity
NMLFEMLE_01614 3.3e-183 ygjR S Oxidoreductase
NMLFEMLE_01615 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NMLFEMLE_01616 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NMLFEMLE_01617 1.4e-275 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NMLFEMLE_01618 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NMLFEMLE_01619 3.6e-249 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NMLFEMLE_01620 4.9e-87 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NMLFEMLE_01621 4.6e-15 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NMLFEMLE_01622 6.8e-129 mcpA NT chemotaxis protein
NMLFEMLE_01623 4.6e-94 mcpA NT chemotaxis protein
NMLFEMLE_01624 8.5e-295 mcpA NT chemotaxis protein
NMLFEMLE_01625 6.9e-220 mcpA NT chemotaxis protein
NMLFEMLE_01626 3.2e-225 mcpA NT chemotaxis protein
NMLFEMLE_01627 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NMLFEMLE_01628 2.3e-35
NMLFEMLE_01629 2.1e-72 yugU S Uncharacterised protein family UPF0047
NMLFEMLE_01630 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NMLFEMLE_01631 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NMLFEMLE_01632 1.4e-116 yugP S Zn-dependent protease
NMLFEMLE_01633 2.3e-38
NMLFEMLE_01634 1.1e-53 mstX S Membrane-integrating protein Mistic
NMLFEMLE_01635 2.2e-182 yugO P COG1226 Kef-type K transport systems
NMLFEMLE_01636 1.4e-71 yugN S YugN-like family
NMLFEMLE_01638 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NMLFEMLE_01639 2.6e-227 yugK C Dehydrogenase
NMLFEMLE_01640 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NMLFEMLE_01641 1.1e-34 yuzA S Domain of unknown function (DUF378)
NMLFEMLE_01642 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NMLFEMLE_01643 2.1e-199 yugH 2.6.1.1 E Aminotransferase
NMLFEMLE_01644 1.6e-85 alaR K Transcriptional regulator
NMLFEMLE_01645 2.5e-155 yugF I Hydrolase
NMLFEMLE_01646 4.6e-39 yugE S Domain of unknown function (DUF1871)
NMLFEMLE_01647 4.9e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NMLFEMLE_01648 1.3e-232 T PhoQ Sensor
NMLFEMLE_01649 7.4e-70 kapB G Kinase associated protein B
NMLFEMLE_01650 4.2e-115 kapD L the KinA pathway to sporulation
NMLFEMLE_01652 1.9e-184 yuxJ EGP Major facilitator Superfamily
NMLFEMLE_01653 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NMLFEMLE_01654 6.3e-75 yuxK S protein conserved in bacteria
NMLFEMLE_01655 6.3e-78 yufK S Family of unknown function (DUF5366)
NMLFEMLE_01656 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NMLFEMLE_01657 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
NMLFEMLE_01658 2.7e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NMLFEMLE_01659 7.8e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NMLFEMLE_01660 1.5e-150 yufP S Belongs to the binding-protein-dependent transport system permease family
NMLFEMLE_01661 8.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
NMLFEMLE_01662 6.3e-233 maeN C COG3493 Na citrate symporter
NMLFEMLE_01663 5e-15
NMLFEMLE_01664 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NMLFEMLE_01665 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMLFEMLE_01666 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMLFEMLE_01667 3.5e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMLFEMLE_01668 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMLFEMLE_01669 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMLFEMLE_01670 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NMLFEMLE_01671 5.1e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
NMLFEMLE_01672 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMLFEMLE_01673 0.0 comP 2.7.13.3 T Histidine kinase
NMLFEMLE_01675 3.5e-137 comQ H Belongs to the FPP GGPP synthase family
NMLFEMLE_01677 1.1e-22 yuzC
NMLFEMLE_01678 3.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NMLFEMLE_01679 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NMLFEMLE_01680 9.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
NMLFEMLE_01681 3e-66 yueI S Protein of unknown function (DUF1694)
NMLFEMLE_01682 7.4e-39 yueH S YueH-like protein
NMLFEMLE_01683 6.6e-31 yueG S Spore germination protein gerPA/gerPF
NMLFEMLE_01684 3.2e-190 yueF S transporter activity
NMLFEMLE_01685 2e-70 S Protein of unknown function (DUF2283)
NMLFEMLE_01686 2.9e-24 S Protein of unknown function (DUF2642)
NMLFEMLE_01687 4.8e-96 yueE S phosphohydrolase
NMLFEMLE_01688 7.1e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMLFEMLE_01689 3.3e-64 yueC S Family of unknown function (DUF5383)
NMLFEMLE_01690 0.0 esaA S type VII secretion protein EsaA
NMLFEMLE_01691 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NMLFEMLE_01692 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
NMLFEMLE_01693 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NMLFEMLE_01694 2.8e-45 esxA S Belongs to the WXG100 family
NMLFEMLE_01695 1.5e-228 yukF QT Transcriptional regulator
NMLFEMLE_01696 1.8e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NMLFEMLE_01697 9.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NMLFEMLE_01698 2.5e-35 mbtH S MbtH-like protein
NMLFEMLE_01699 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMLFEMLE_01700 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NMLFEMLE_01701 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NMLFEMLE_01702 1.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
NMLFEMLE_01703 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMLFEMLE_01704 3.9e-167 besA S Putative esterase
NMLFEMLE_01705 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
NMLFEMLE_01706 4.4e-93 bioY S Biotin biosynthesis protein
NMLFEMLE_01707 3.9e-211 yuiF S antiporter
NMLFEMLE_01708 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NMLFEMLE_01709 2e-77 yuiD S protein conserved in bacteria
NMLFEMLE_01710 3e-116 yuiC S protein conserved in bacteria
NMLFEMLE_01711 1.2e-25 yuiB S Putative membrane protein
NMLFEMLE_01712 1.2e-235 yumB 1.6.99.3 C NADH dehydrogenase
NMLFEMLE_01713 1.7e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
NMLFEMLE_01715 7.9e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NMLFEMLE_01716 7.2e-115 paiB K Putative FMN-binding domain
NMLFEMLE_01717 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMLFEMLE_01718 3.7e-63 erpA S Belongs to the HesB IscA family
NMLFEMLE_01719 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NMLFEMLE_01720 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMLFEMLE_01721 3.2e-39 yuzB S Belongs to the UPF0349 family
NMLFEMLE_01722 2.7e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NMLFEMLE_01723 8.7e-56 yuzD S protein conserved in bacteria
NMLFEMLE_01724 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NMLFEMLE_01725 5e-271 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NMLFEMLE_01726 2.7e-69 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NMLFEMLE_01727 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NMLFEMLE_01728 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NMLFEMLE_01729 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
NMLFEMLE_01730 1e-198 yutH S Spore coat protein
NMLFEMLE_01731 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NMLFEMLE_01732 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NMLFEMLE_01733 1e-75 yutE S Protein of unknown function DUF86
NMLFEMLE_01734 9.7e-48 yutD S protein conserved in bacteria
NMLFEMLE_01735 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMLFEMLE_01736 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NMLFEMLE_01737 1.3e-195 lytH M Peptidase, M23
NMLFEMLE_01738 3.9e-131 yunB S Sporulation protein YunB (Spo_YunB)
NMLFEMLE_01739 5.3e-47 yunC S Domain of unknown function (DUF1805)
NMLFEMLE_01740 3.9e-262 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NMLFEMLE_01741 4.5e-141 yunE S membrane transporter protein
NMLFEMLE_01742 4.3e-171 yunF S Protein of unknown function DUF72
NMLFEMLE_01743 2.8e-60 yunG
NMLFEMLE_01744 4.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NMLFEMLE_01745 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
NMLFEMLE_01746 1e-230 pbuX F Permease family
NMLFEMLE_01747 1.6e-222 pbuX F xanthine
NMLFEMLE_01748 2.4e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NMLFEMLE_01749 1.7e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NMLFEMLE_01751 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NMLFEMLE_01752 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NMLFEMLE_01753 3.7e-151 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NMLFEMLE_01754 3.1e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NMLFEMLE_01755 2.1e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NMLFEMLE_01757 1e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NMLFEMLE_01758 1.4e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NMLFEMLE_01759 2.4e-169 bsn L Ribonuclease
NMLFEMLE_01760 1.2e-205 msmX P Belongs to the ABC transporter superfamily
NMLFEMLE_01761 1.1e-135 yurK K UTRA
NMLFEMLE_01762 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NMLFEMLE_01763 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
NMLFEMLE_01764 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
NMLFEMLE_01765 1.2e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NMLFEMLE_01766 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NMLFEMLE_01767 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NMLFEMLE_01768 3.2e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NMLFEMLE_01770 1e-41
NMLFEMLE_01771 8.3e-28
NMLFEMLE_01775 4e-108 S aspartate phosphatase
NMLFEMLE_01776 3e-283 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMLFEMLE_01777 2.4e-83 S SMI1-KNR4 cell-wall
NMLFEMLE_01778 1.5e-127 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NMLFEMLE_01779 7.1e-58 S Bacteriophage holin family
NMLFEMLE_01780 5.9e-96 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
NMLFEMLE_01782 1.3e-12
NMLFEMLE_01783 3.1e-84
NMLFEMLE_01784 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
NMLFEMLE_01785 1.5e-107 mur1 NU Prophage endopeptidase tail
NMLFEMLE_01786 2.6e-43 S Phage tail protein
NMLFEMLE_01787 6.6e-151 D Phage-related minor tail protein
NMLFEMLE_01789 6e-53 S phage major tail protein, phi13 family
NMLFEMLE_01790 2.2e-18
NMLFEMLE_01791 1.9e-15 S Bacteriophage HK97-gp10, putative tail-component
NMLFEMLE_01792 1.2e-07 S head-tail adaptor
NMLFEMLE_01793 1e-10 S Phage gp6-like head-tail connector protein
NMLFEMLE_01794 5e-64 S Phage capsid family
NMLFEMLE_01795 5.5e-48 S Caudovirus prohead serine protease
NMLFEMLE_01796 4.3e-105 S Phage portal protein
NMLFEMLE_01797 1.3e-150 S Phage Terminase
NMLFEMLE_01798 4.5e-17
NMLFEMLE_01799 3.5e-27 L HNH endonuclease
NMLFEMLE_01802 3.2e-141
NMLFEMLE_01803 1.3e-21
NMLFEMLE_01804 9.7e-170 dnaB 3.6.4.12 L replicative DNA helicase
NMLFEMLE_01805 5.1e-25 S Loader and inhibitor of phage G40P
NMLFEMLE_01806 4.4e-82 L DnaD domain protein
NMLFEMLE_01808 4.8e-13
NMLFEMLE_01809 6e-88 S Phage regulatory protein Rha (Phage_pRha)
NMLFEMLE_01810 1.1e-60 S Hypothetical protein (DUF2513)
NMLFEMLE_01811 8.7e-23
NMLFEMLE_01814 3.6e-23
NMLFEMLE_01816 3.1e-25 K Helix-turn-helix XRE-family like proteins
NMLFEMLE_01817 1.6e-42 E Zn peptidase
NMLFEMLE_01818 1.5e-150 S Pfam:Arm-DNA-bind_4
NMLFEMLE_01819 3.5e-271 sufB O FeS cluster assembly
NMLFEMLE_01820 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NMLFEMLE_01821 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NMLFEMLE_01822 4.5e-244 sufD O assembly protein SufD
NMLFEMLE_01823 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NMLFEMLE_01824 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NMLFEMLE_01825 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
NMLFEMLE_01826 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NMLFEMLE_01827 2.4e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NMLFEMLE_01828 2.4e-56 yusD S SCP-2 sterol transfer family
NMLFEMLE_01829 5.6e-55 traF CO Thioredoxin
NMLFEMLE_01830 1.3e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NMLFEMLE_01831 1.1e-39 yusG S Protein of unknown function (DUF2553)
NMLFEMLE_01832 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NMLFEMLE_01833 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NMLFEMLE_01834 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NMLFEMLE_01835 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
NMLFEMLE_01836 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NMLFEMLE_01837 8.1e-09 S YuzL-like protein
NMLFEMLE_01838 7.1e-164 fadM E Proline dehydrogenase
NMLFEMLE_01839 5.1e-40
NMLFEMLE_01840 5.4e-53 yusN M Coat F domain
NMLFEMLE_01841 8.9e-10 yusO K Iron dependent repressor, N-terminal DNA binding domain
NMLFEMLE_01842 2.8e-52 yusO K Iron dependent repressor, N-terminal DNA binding domain
NMLFEMLE_01843 3.2e-292 yusP P Major facilitator superfamily
NMLFEMLE_01844 2.7e-64 yusQ S Tautomerase enzyme
NMLFEMLE_01845 1.3e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMLFEMLE_01846 5.7e-158 yusT K LysR substrate binding domain
NMLFEMLE_01847 3.8e-47 yusU S Protein of unknown function (DUF2573)
NMLFEMLE_01848 1e-153 yusV 3.6.3.34 HP ABC transporter
NMLFEMLE_01849 9.8e-19 S YusW-like protein
NMLFEMLE_01850 4.3e-19 S YusW-like protein
NMLFEMLE_01851 1.1e-301 pepF2 E COG1164 Oligoendopeptidase F
NMLFEMLE_01852 1.2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMLFEMLE_01853 4.7e-79 dps P Ferritin-like domain
NMLFEMLE_01854 1.6e-236 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMLFEMLE_01855 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMLFEMLE_01856 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
NMLFEMLE_01857 1.3e-157 yuxN K Transcriptional regulator
NMLFEMLE_01858 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NMLFEMLE_01859 1.1e-23 S Protein of unknown function (DUF3970)
NMLFEMLE_01860 2e-181 gerAA EG Spore germination protein
NMLFEMLE_01861 2.9e-48 gerAA EG Spore germination protein
NMLFEMLE_01862 9.1e-198 gerAB E Spore germination protein
NMLFEMLE_01863 6.2e-91 gerAC S Spore germination B3/ GerAC like, C-terminal
NMLFEMLE_01864 1.1e-50 gerAC S Spore germination B3/ GerAC like, C-terminal
NMLFEMLE_01865 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMLFEMLE_01866 5.5e-187 vraS 2.7.13.3 T Histidine kinase
NMLFEMLE_01867 4.7e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NMLFEMLE_01868 4.8e-125 liaG S Putative adhesin
NMLFEMLE_01869 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NMLFEMLE_01870 5.6e-62 liaI S membrane
NMLFEMLE_01871 1.4e-226 yvqJ EGP Major facilitator Superfamily
NMLFEMLE_01872 2.7e-100 yvqK 2.5.1.17 S Adenosyltransferase
NMLFEMLE_01873 4.7e-241 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NMLFEMLE_01874 8.4e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMLFEMLE_01875 1.3e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NMLFEMLE_01876 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMLFEMLE_01877 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
NMLFEMLE_01878 0.0 T PhoQ Sensor
NMLFEMLE_01879 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMLFEMLE_01880 3.6e-22
NMLFEMLE_01881 1.6e-97 yvrI K RNA polymerase
NMLFEMLE_01882 2.4e-19 S YvrJ protein family
NMLFEMLE_01883 3.1e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
NMLFEMLE_01884 1.1e-63 yvrL S Regulatory protein YrvL
NMLFEMLE_01885 4.1e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NMLFEMLE_01886 1.6e-123 macB V ABC transporter, ATP-binding protein
NMLFEMLE_01887 7.6e-174 M Efflux transporter rnd family, mfp subunit
NMLFEMLE_01888 4.9e-148 fhuC 3.6.3.34 HP ABC transporter
NMLFEMLE_01889 6.9e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMLFEMLE_01890 7.9e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMLFEMLE_01891 1.2e-177 fhuD P ABC transporter
NMLFEMLE_01892 4.9e-236 yvsH E Arginine ornithine antiporter
NMLFEMLE_01893 6.5e-16 S Small spore protein J (Spore_SspJ)
NMLFEMLE_01894 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NMLFEMLE_01895 3.6e-296 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMLFEMLE_01896 7e-43 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMLFEMLE_01897 9.2e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NMLFEMLE_01898 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NMLFEMLE_01899 6.9e-119 modB P COG4149 ABC-type molybdate transport system, permease component
NMLFEMLE_01900 1.1e-155 yvgN S reductase
NMLFEMLE_01901 5.4e-86 yvgO
NMLFEMLE_01902 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NMLFEMLE_01903 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NMLFEMLE_01904 1.4e-211 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NMLFEMLE_01905 4e-101 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NMLFEMLE_01906 0.0 helD 3.6.4.12 L DNA helicase
NMLFEMLE_01907 4.1e-107 yvgT S membrane
NMLFEMLE_01908 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
NMLFEMLE_01909 1.6e-104 bdbD O Thioredoxin
NMLFEMLE_01910 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NMLFEMLE_01911 0.0 copA 3.6.3.54 P P-type ATPase
NMLFEMLE_01912 5.9e-29 copZ P Copper resistance protein CopZ
NMLFEMLE_01913 2.2e-48 csoR S transcriptional
NMLFEMLE_01914 2.1e-31 yvaA 1.1.1.371 S Oxidoreductase
NMLFEMLE_01915 1.5e-141 yvaA 1.1.1.371 S Oxidoreductase
NMLFEMLE_01916 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NMLFEMLE_01917 0.0 yvaC S Fusaric acid resistance protein-like
NMLFEMLE_01918 5.7e-73 yvaD S Family of unknown function (DUF5360)
NMLFEMLE_01919 6.3e-55 yvaE P Small Multidrug Resistance protein
NMLFEMLE_01920 8.7e-96 K Bacterial regulatory proteins, tetR family
NMLFEMLE_01921 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMLFEMLE_01923 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NMLFEMLE_01924 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NMLFEMLE_01925 4.5e-48 est 3.1.1.1 S Carboxylesterase
NMLFEMLE_01926 3.8e-81 est 3.1.1.1 S Carboxylesterase
NMLFEMLE_01927 2.4e-23 secG U Preprotein translocase subunit SecG
NMLFEMLE_01928 3.8e-150 yvaM S Serine aminopeptidase, S33
NMLFEMLE_01929 7.5e-36 yvzC K Transcriptional
NMLFEMLE_01930 4e-69 K transcriptional
NMLFEMLE_01931 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
NMLFEMLE_01932 2.2e-54 yodB K transcriptional
NMLFEMLE_01933 1.9e-218 NT chemotaxis protein
NMLFEMLE_01934 1.5e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NMLFEMLE_01935 4.8e-168 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NMLFEMLE_01936 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NMLFEMLE_01937 1.3e-114 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NMLFEMLE_01938 4.7e-74 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NMLFEMLE_01939 3.3e-60 yvbF K Belongs to the GbsR family
NMLFEMLE_01940 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NMLFEMLE_01941 3.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NMLFEMLE_01942 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NMLFEMLE_01943 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NMLFEMLE_01944 3.5e-97 yvbF K Belongs to the GbsR family
NMLFEMLE_01945 2.4e-102 yvbG U UPF0056 membrane protein
NMLFEMLE_01946 1.9e-112 yvbH S YvbH-like oligomerisation region
NMLFEMLE_01947 1e-122 exoY M Membrane
NMLFEMLE_01948 0.0 tcaA S response to antibiotic
NMLFEMLE_01949 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
NMLFEMLE_01950 2.7e-174 EGP Major facilitator Superfamily
NMLFEMLE_01951 3.7e-152
NMLFEMLE_01952 2.3e-114 S GlcNAc-PI de-N-acetylase
NMLFEMLE_01953 1.4e-122 C WbqC-like protein family
NMLFEMLE_01954 5e-114 M Protein involved in cellulose biosynthesis
NMLFEMLE_01955 1.1e-156 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NMLFEMLE_01956 9.6e-148 5.1.3.2 M GDP-mannose 4,6 dehydratase
NMLFEMLE_01957 1.6e-184 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NMLFEMLE_01958 2.8e-217 1.1.1.136 M UDP binding domain
NMLFEMLE_01959 1.1e-165 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NMLFEMLE_01960 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NMLFEMLE_01961 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NMLFEMLE_01962 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NMLFEMLE_01963 6.5e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NMLFEMLE_01964 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NMLFEMLE_01965 1.8e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NMLFEMLE_01966 6.1e-146 araE EGP Major facilitator Superfamily
NMLFEMLE_01967 2.3e-58 araE EGP Major facilitator Superfamily
NMLFEMLE_01968 5.5e-203 araR K transcriptional
NMLFEMLE_01969 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMLFEMLE_01970 5.1e-159 yvbU K Transcriptional regulator
NMLFEMLE_01971 1.2e-155 yvbV EG EamA-like transporter family
NMLFEMLE_01972 3.7e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NMLFEMLE_01973 4.4e-194 yvbX S Glycosyl hydrolase
NMLFEMLE_01974 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NMLFEMLE_01975 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NMLFEMLE_01976 3.8e-125 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NMLFEMLE_01977 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMLFEMLE_01978 1.9e-198 desK 2.7.13.3 T Histidine kinase
NMLFEMLE_01979 3.8e-114 yvfS V COG0842 ABC-type multidrug transport system, permease component
NMLFEMLE_01980 6.6e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NMLFEMLE_01981 2.9e-156 rsbQ S Alpha/beta hydrolase family
NMLFEMLE_01982 1.2e-198 rsbU 3.1.3.3 T response regulator
NMLFEMLE_01983 1.7e-248 galA 3.2.1.89 G arabinogalactan
NMLFEMLE_01984 0.0 lacA 3.2.1.23 G beta-galactosidase
NMLFEMLE_01985 7.2e-150 ganQ P transport
NMLFEMLE_01986 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
NMLFEMLE_01987 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
NMLFEMLE_01988 1.8e-184 lacR K Transcriptional regulator
NMLFEMLE_01989 1.5e-89 yvfI K COG2186 Transcriptional regulators
NMLFEMLE_01990 2.6e-308 yvfH C L-lactate permease
NMLFEMLE_01991 4.4e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NMLFEMLE_01992 1e-31 yvfG S YvfG protein
NMLFEMLE_01993 2.9e-187 yvfF GM Exopolysaccharide biosynthesis protein
NMLFEMLE_01994 1.5e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NMLFEMLE_01995 6.6e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NMLFEMLE_01996 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NMLFEMLE_01997 2.8e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMLFEMLE_01998 3.3e-189 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NMLFEMLE_01999 4.4e-205 epsI GM pyruvyl transferase
NMLFEMLE_02000 5.8e-194 epsH GT2 S Glycosyltransferase like family 2
NMLFEMLE_02001 1.1e-206 epsG S EpsG family
NMLFEMLE_02002 1.4e-217 epsF GT4 M Glycosyl transferases group 1
NMLFEMLE_02003 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NMLFEMLE_02004 2e-224 epsD GT4 M Glycosyl transferase 4-like
NMLFEMLE_02005 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NMLFEMLE_02006 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NMLFEMLE_02007 4e-122 ywqC M biosynthesis protein
NMLFEMLE_02008 6.3e-76 slr K transcriptional
NMLFEMLE_02009 1.8e-281 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NMLFEMLE_02011 4.6e-93 padC Q Phenolic acid decarboxylase
NMLFEMLE_02012 2.1e-71 MA20_18690 S Protein of unknown function (DUF3237)
NMLFEMLE_02013 2.8e-102 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NMLFEMLE_02014 3.5e-260 pbpE V Beta-lactamase
NMLFEMLE_02015 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NMLFEMLE_02016 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NMLFEMLE_02017 1.8e-295 yveA E amino acid
NMLFEMLE_02018 2.6e-106 yvdT K Transcriptional regulator
NMLFEMLE_02019 7.4e-50 ykkC P Small Multidrug Resistance protein
NMLFEMLE_02020 4.1e-50 sugE P Small Multidrug Resistance protein
NMLFEMLE_02021 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
NMLFEMLE_02022 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
NMLFEMLE_02023 1.2e-182 S Patatin-like phospholipase
NMLFEMLE_02025 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NMLFEMLE_02026 2.3e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NMLFEMLE_02027 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NMLFEMLE_02028 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NMLFEMLE_02029 2.2e-154 malA S Protein of unknown function (DUF1189)
NMLFEMLE_02030 3.9e-148 malD P transport
NMLFEMLE_02031 2.9e-243 malC P COG1175 ABC-type sugar transport systems, permease components
NMLFEMLE_02032 2.6e-233 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NMLFEMLE_02033 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NMLFEMLE_02034 1e-173 yvdE K Transcriptional regulator
NMLFEMLE_02035 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NMLFEMLE_02036 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
NMLFEMLE_02037 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NMLFEMLE_02038 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NMLFEMLE_02039 1.9e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMLFEMLE_02040 0.0 yxdM V ABC transporter (permease)
NMLFEMLE_02041 7.3e-141 yvcR V ABC transporter, ATP-binding protein
NMLFEMLE_02042 1.3e-196 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NMLFEMLE_02043 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMLFEMLE_02044 3.9e-33
NMLFEMLE_02045 5.4e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NMLFEMLE_02046 1.6e-36 crh G Phosphocarrier protein Chr
NMLFEMLE_02047 1.4e-170 whiA K May be required for sporulation
NMLFEMLE_02048 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NMLFEMLE_02049 5.7e-166 rapZ S Displays ATPase and GTPase activities
NMLFEMLE_02050 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NMLFEMLE_02051 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NMLFEMLE_02052 1.4e-102 usp CBM50 M protein conserved in bacteria
NMLFEMLE_02053 2.4e-278 S COG0457 FOG TPR repeat
NMLFEMLE_02054 0.0 msbA2 3.6.3.44 V ABC transporter
NMLFEMLE_02056 4.5e-253
NMLFEMLE_02057 2.3e-69
NMLFEMLE_02058 3.1e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NMLFEMLE_02059 4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NMLFEMLE_02060 8.4e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NMLFEMLE_02061 6.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NMLFEMLE_02062 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NMLFEMLE_02063 3.9e-151 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NMLFEMLE_02064 1.3e-61 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NMLFEMLE_02065 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NMLFEMLE_02066 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NMLFEMLE_02067 1.5e-138 yvpB NU protein conserved in bacteria
NMLFEMLE_02068 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NMLFEMLE_02069 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NMLFEMLE_02070 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NMLFEMLE_02071 5.3e-162 yvoD P COG0370 Fe2 transport system protein B
NMLFEMLE_02072 2.7e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NMLFEMLE_02073 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NMLFEMLE_02074 3.9e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NMLFEMLE_02075 5e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NMLFEMLE_02076 1.8e-133 yvoA K transcriptional
NMLFEMLE_02077 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NMLFEMLE_02078 1.2e-50 yvlD S Membrane
NMLFEMLE_02079 2.6e-26 pspB KT PspC domain
NMLFEMLE_02080 2.4e-166 yvlB S Putative adhesin
NMLFEMLE_02081 8e-49 yvlA
NMLFEMLE_02082 5.7e-33 yvkN
NMLFEMLE_02083 8.2e-49 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMLFEMLE_02084 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NMLFEMLE_02085 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NMLFEMLE_02086 1.2e-30 csbA S protein conserved in bacteria
NMLFEMLE_02087 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NMLFEMLE_02088 1.6e-100 yvkB K Transcriptional regulator
NMLFEMLE_02089 1.6e-225 yvkA EGP Major facilitator Superfamily
NMLFEMLE_02090 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMLFEMLE_02091 5.3e-56 swrA S Swarming motility protein
NMLFEMLE_02092 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NMLFEMLE_02093 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NMLFEMLE_02094 1.6e-123 ftsE D cell division ATP-binding protein FtsE
NMLFEMLE_02095 2e-55 cccB C COG2010 Cytochrome c, mono- and diheme variants
NMLFEMLE_02096 9.3e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NMLFEMLE_02097 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NMLFEMLE_02098 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NMLFEMLE_02099 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NMLFEMLE_02100 2.8e-66
NMLFEMLE_02101 1.4e-08 fliT S bacterial-type flagellum organization
NMLFEMLE_02102 1.1e-68 fliS N flagellar protein FliS
NMLFEMLE_02103 2e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NMLFEMLE_02104 1.2e-55 flaG N flagellar protein FlaG
NMLFEMLE_02105 1.4e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMLFEMLE_02106 2.8e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NMLFEMLE_02107 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NMLFEMLE_02108 5.7e-50 yviE
NMLFEMLE_02109 7.8e-155 flgL N Belongs to the bacterial flagellin family
NMLFEMLE_02110 2.7e-264 flgK N flagellar hook-associated protein
NMLFEMLE_02111 3.8e-63 flgN NOU FlgN protein
NMLFEMLE_02112 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
NMLFEMLE_02113 7e-74 yvyF S flagellar protein
NMLFEMLE_02114 8.1e-73 comFC S Phosphoribosyl transferase domain
NMLFEMLE_02115 1.1e-44 comFB S Late competence development protein ComFB
NMLFEMLE_02116 6.4e-265 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NMLFEMLE_02117 2.1e-154 degV S protein conserved in bacteria
NMLFEMLE_02118 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMLFEMLE_02119 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NMLFEMLE_02120 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NMLFEMLE_02121 6e-163 yvhJ K Transcriptional regulator
NMLFEMLE_02122 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NMLFEMLE_02123 3.2e-236 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NMLFEMLE_02124 4.7e-145 tuaG GT2 M Glycosyltransferase like family 2
NMLFEMLE_02125 9.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
NMLFEMLE_02126 1.8e-262 tuaE M Teichuronic acid biosynthesis protein
NMLFEMLE_02127 3.2e-164 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMLFEMLE_02128 5e-71 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMLFEMLE_02129 5.3e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NMLFEMLE_02130 1.3e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMLFEMLE_02131 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NMLFEMLE_02132 3.3e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMLFEMLE_02133 1.1e-265 lytB 3.5.1.28 D Stage II sporulation protein
NMLFEMLE_02134 7.3e-69 lytB 3.5.1.28 D Stage II sporulation protein
NMLFEMLE_02135 6e-38
NMLFEMLE_02136 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NMLFEMLE_02137 1.6e-216 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NMLFEMLE_02138 5.8e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NMLFEMLE_02139 1.1e-257 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NMLFEMLE_02140 7e-150 tagG GM Transport permease protein
NMLFEMLE_02141 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NMLFEMLE_02142 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
NMLFEMLE_02143 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NMLFEMLE_02144 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NMLFEMLE_02145 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NMLFEMLE_02146 4.3e-39
NMLFEMLE_02147 3.5e-171
NMLFEMLE_02148 4e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NMLFEMLE_02149 2.5e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NMLFEMLE_02150 3.8e-244 gerBA EG Spore germination protein
NMLFEMLE_02151 4.7e-186 gerBB E Spore germination protein
NMLFEMLE_02152 1.2e-197 gerAC S Spore germination protein
NMLFEMLE_02153 4.1e-248 ywtG EGP Major facilitator Superfamily
NMLFEMLE_02154 2.3e-168 ywtF K Transcriptional regulator
NMLFEMLE_02155 4.2e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NMLFEMLE_02156 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NMLFEMLE_02157 3.6e-21 ywtC
NMLFEMLE_02158 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NMLFEMLE_02159 8.6e-70 pgsC S biosynthesis protein
NMLFEMLE_02160 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NMLFEMLE_02161 9.3e-178 rbsR K transcriptional
NMLFEMLE_02162 1.9e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NMLFEMLE_02163 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NMLFEMLE_02164 3.3e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NMLFEMLE_02165 1.3e-152 rbsC G Belongs to the binding-protein-dependent transport system permease family
NMLFEMLE_02166 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NMLFEMLE_02167 3e-93 batE T Sh3 type 3 domain protein
NMLFEMLE_02168 8e-48 ywsA S Protein of unknown function (DUF3892)
NMLFEMLE_02169 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NMLFEMLE_02170 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NMLFEMLE_02171 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NMLFEMLE_02172 1.1e-169 alsR K LysR substrate binding domain
NMLFEMLE_02173 2.1e-127 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NMLFEMLE_02174 5.7e-71 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NMLFEMLE_02175 1.1e-124 ywrJ
NMLFEMLE_02176 7.3e-131 cotB
NMLFEMLE_02177 1.3e-209 cotH M Spore Coat
NMLFEMLE_02178 3.7e-12
NMLFEMLE_02179 1.1e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NMLFEMLE_02180 5e-54 S Domain of unknown function (DUF4181)
NMLFEMLE_02181 2.3e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NMLFEMLE_02182 8e-82 ywrC K Transcriptional regulator
NMLFEMLE_02183 1.2e-103 ywrB P Chromate transporter
NMLFEMLE_02184 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
NMLFEMLE_02186 8.8e-101 ywqN S NAD(P)H-dependent
NMLFEMLE_02187 4.2e-161 K Transcriptional regulator
NMLFEMLE_02188 6.7e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NMLFEMLE_02189 3.9e-25
NMLFEMLE_02190 1e-241 ywqJ S Pre-toxin TG
NMLFEMLE_02191 1.3e-38 ywqI S Family of unknown function (DUF5344)
NMLFEMLE_02192 3.3e-15 S Domain of unknown function (DUF5082)
NMLFEMLE_02193 4.9e-153 ywqG S Domain of unknown function (DUF1963)
NMLFEMLE_02194 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMLFEMLE_02195 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NMLFEMLE_02196 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NMLFEMLE_02197 2e-116 ywqC M biosynthesis protein
NMLFEMLE_02198 1.2e-17
NMLFEMLE_02199 2.1e-307 ywqB S SWIM zinc finger
NMLFEMLE_02200 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NMLFEMLE_02201 1.1e-153 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NMLFEMLE_02202 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
NMLFEMLE_02203 3.7e-57 ssbB L Single-stranded DNA-binding protein
NMLFEMLE_02204 1.9e-65 ywpG
NMLFEMLE_02205 1.1e-66 ywpF S YwpF-like protein
NMLFEMLE_02206 4e-50 srtA 3.4.22.70 M Sortase family
NMLFEMLE_02207 1.2e-152 ywpD T Histidine kinase
NMLFEMLE_02208 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NMLFEMLE_02209 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NMLFEMLE_02210 2.6e-197 S aspartate phosphatase
NMLFEMLE_02211 2.6e-141 flhP N flagellar basal body
NMLFEMLE_02212 2.9e-124 flhO N flagellar basal body
NMLFEMLE_02213 3.5e-180 mbl D Rod shape-determining protein
NMLFEMLE_02214 3e-44 spoIIID K Stage III sporulation protein D
NMLFEMLE_02215 2.1e-70 ywoH K COG1846 Transcriptional regulators
NMLFEMLE_02216 2.7e-211 ywoG EGP Major facilitator Superfamily
NMLFEMLE_02217 1.4e-230 ywoF P Right handed beta helix region
NMLFEMLE_02218 4.3e-225 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NMLFEMLE_02219 8.1e-42 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NMLFEMLE_02220 3.1e-240 ywoD EGP Major facilitator superfamily
NMLFEMLE_02221 1.5e-103 phzA Q Isochorismatase family
NMLFEMLE_02222 8.3e-76
NMLFEMLE_02223 3.3e-225 amt P Ammonium transporter
NMLFEMLE_02224 1.6e-58 nrgB K Belongs to the P(II) protein family
NMLFEMLE_02225 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NMLFEMLE_02226 2.4e-69 ywnJ S VanZ like family
NMLFEMLE_02227 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NMLFEMLE_02228 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NMLFEMLE_02229 2.7e-14 ywnC S Family of unknown function (DUF5362)
NMLFEMLE_02230 2.2e-70 ywnF S Family of unknown function (DUF5392)
NMLFEMLE_02231 2.7e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMLFEMLE_02232 8.5e-142 mta K transcriptional
NMLFEMLE_02233 2.6e-59 ywnC S Family of unknown function (DUF5362)
NMLFEMLE_02234 1.1e-113 ywnB S NAD(P)H-binding
NMLFEMLE_02235 2.8e-64 ywnA K Transcriptional regulator
NMLFEMLE_02236 1.7e-237 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NMLFEMLE_02237 7.5e-69 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NMLFEMLE_02238 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NMLFEMLE_02239 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NMLFEMLE_02241 3.2e-10 csbD K CsbD-like
NMLFEMLE_02242 3e-84 ywmF S Peptidase M50
NMLFEMLE_02243 2.8e-07 S response regulator aspartate phosphatase
NMLFEMLE_02244 1.6e-71 S response regulator aspartate phosphatase
NMLFEMLE_02245 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NMLFEMLE_02246 3.8e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NMLFEMLE_02248 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NMLFEMLE_02249 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NMLFEMLE_02250 3.5e-175 spoIID D Stage II sporulation protein D
NMLFEMLE_02251 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMLFEMLE_02252 8.5e-131 ywmB S TATA-box binding
NMLFEMLE_02253 1.3e-32 ywzB S membrane
NMLFEMLE_02254 3.1e-86 ywmA
NMLFEMLE_02255 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NMLFEMLE_02256 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NMLFEMLE_02257 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NMLFEMLE_02258 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NMLFEMLE_02259 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMLFEMLE_02260 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NMLFEMLE_02261 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMLFEMLE_02262 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NMLFEMLE_02263 2.5e-62 atpI S ATP synthase
NMLFEMLE_02264 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NMLFEMLE_02265 4.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NMLFEMLE_02266 7.2e-95 ywlG S Belongs to the UPF0340 family
NMLFEMLE_02267 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NMLFEMLE_02268 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMLFEMLE_02269 1.7e-91 mntP P Probably functions as a manganese efflux pump
NMLFEMLE_02270 3.1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NMLFEMLE_02271 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NMLFEMLE_02272 3e-111 spoIIR S stage II sporulation protein R
NMLFEMLE_02273 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
NMLFEMLE_02275 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NMLFEMLE_02276 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NMLFEMLE_02277 3.8e-66 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMLFEMLE_02278 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NMLFEMLE_02279 8.6e-160 ywkB S Membrane transport protein
NMLFEMLE_02280 0.0 sfcA 1.1.1.38 C malic enzyme
NMLFEMLE_02281 7e-104 tdk 2.7.1.21 F thymidine kinase
NMLFEMLE_02282 1.1e-32 rpmE J Binds the 23S rRNA
NMLFEMLE_02283 4.7e-51 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NMLFEMLE_02284 4.8e-155 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NMLFEMLE_02285 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NMLFEMLE_02286 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMLFEMLE_02287 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NMLFEMLE_02288 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NMLFEMLE_02289 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NMLFEMLE_02290 2.3e-90 ywjG S Domain of unknown function (DUF2529)
NMLFEMLE_02291 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NMLFEMLE_02292 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NMLFEMLE_02293 9.7e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NMLFEMLE_02294 0.0 fadF C COG0247 Fe-S oxidoreductase
NMLFEMLE_02295 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NMLFEMLE_02296 2.1e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NMLFEMLE_02297 2.7e-42 ywjC
NMLFEMLE_02298 7.3e-91 ywjB H RibD C-terminal domain
NMLFEMLE_02299 0.0 ywjA V ABC transporter
NMLFEMLE_02300 2.1e-117 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMLFEMLE_02301 2.6e-158 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMLFEMLE_02302 2.6e-123 narI 1.7.5.1 C nitrate reductase, gamma
NMLFEMLE_02303 2.4e-93 narJ 1.7.5.1 C nitrate reductase
NMLFEMLE_02304 3.3e-296 narH 1.7.5.1 C Nitrate reductase, beta
NMLFEMLE_02305 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMLFEMLE_02306 7e-86 arfM T cyclic nucleotide binding
NMLFEMLE_02307 7.2e-102 ywiC S YwiC-like protein
NMLFEMLE_02308 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
NMLFEMLE_02309 1.3e-213 narK P COG2223 Nitrate nitrite transporter
NMLFEMLE_02310 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NMLFEMLE_02311 4.7e-73 ywiB S protein conserved in bacteria
NMLFEMLE_02312 2.5e-07 S Bacteriocin subtilosin A
NMLFEMLE_02313 4.9e-270 C Fe-S oxidoreductases
NMLFEMLE_02315 3.3e-132 cbiO V ABC transporter
NMLFEMLE_02316 1.5e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NMLFEMLE_02317 5.5e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
NMLFEMLE_02318 1e-248 L Peptidase, M16
NMLFEMLE_02320 1.8e-243 ywhL CO amine dehydrogenase activity
NMLFEMLE_02321 2.7e-191 ywhK CO amine dehydrogenase activity
NMLFEMLE_02322 2e-78 S aspartate phosphatase
NMLFEMLE_02326 1.7e-20
NMLFEMLE_02329 1.4e-57 V ATPases associated with a variety of cellular activities
NMLFEMLE_02331 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
NMLFEMLE_02332 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NMLFEMLE_02333 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NMLFEMLE_02334 3.4e-94 ywhD S YwhD family
NMLFEMLE_02335 5.1e-119 ywhC S Peptidase family M50
NMLFEMLE_02336 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NMLFEMLE_02337 9.5e-71 ywhA K Transcriptional regulator
NMLFEMLE_02338 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMLFEMLE_02340 9.7e-237 mmr U Major Facilitator Superfamily
NMLFEMLE_02341 6.9e-78 yffB K Transcriptional regulator
NMLFEMLE_02342 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
NMLFEMLE_02343 5.1e-256 ywfO S COG1078 HD superfamily phosphohydrolases
NMLFEMLE_02344 3.1e-36 ywzC S Belongs to the UPF0741 family
NMLFEMLE_02345 5.1e-110 rsfA_1
NMLFEMLE_02346 9.2e-156 ywfM EG EamA-like transporter family
NMLFEMLE_02347 5.6e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NMLFEMLE_02348 1.1e-156 cysL K Transcriptional regulator
NMLFEMLE_02349 1.6e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NMLFEMLE_02350 1.1e-146 ywfI C May function as heme-dependent peroxidase
NMLFEMLE_02351 2.2e-137 IQ Enoyl-(Acyl carrier protein) reductase
NMLFEMLE_02352 1.6e-232 ywfG 2.6.1.83 E Aminotransferase class I and II
NMLFEMLE_02353 7.3e-209 bacE EGP Major facilitator Superfamily
NMLFEMLE_02354 4e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NMLFEMLE_02355 1.1e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMLFEMLE_02356 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NMLFEMLE_02357 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NMLFEMLE_02358 2.3e-205 ywfA EGP Major facilitator Superfamily
NMLFEMLE_02359 4e-262 lysP E amino acid
NMLFEMLE_02360 5.5e-97 rocB E arginine degradation protein
NMLFEMLE_02361 2.1e-218 rocB E arginine degradation protein
NMLFEMLE_02362 6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NMLFEMLE_02363 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NMLFEMLE_02364 1.2e-77
NMLFEMLE_02365 3.5e-87 spsL 5.1.3.13 M Spore Coat
NMLFEMLE_02366 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NMLFEMLE_02367 1.1e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NMLFEMLE_02368 9.3e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NMLFEMLE_02369 9.7e-186 spsG M Spore Coat
NMLFEMLE_02370 5e-128 spsF M Spore Coat
NMLFEMLE_02371 3.3e-211 spsE 2.5.1.56 M acid synthase
NMLFEMLE_02372 1.2e-163 spsD 2.3.1.210 K Spore Coat
NMLFEMLE_02373 3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
NMLFEMLE_02374 2.6e-266 spsB M Capsule polysaccharide biosynthesis protein
NMLFEMLE_02375 1.8e-144 spsA M Spore Coat
NMLFEMLE_02376 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NMLFEMLE_02377 4.3e-59 ywdK S small membrane protein
NMLFEMLE_02378 3.7e-238 ywdJ F Xanthine uracil
NMLFEMLE_02379 5e-48 ywdI S Family of unknown function (DUF5327)
NMLFEMLE_02380 4.7e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NMLFEMLE_02381 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NMLFEMLE_02382 6.1e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
NMLFEMLE_02383 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NMLFEMLE_02384 2e-28 ywdA
NMLFEMLE_02385 4.6e-243 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NMLFEMLE_02386 7.3e-39 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NMLFEMLE_02387 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMLFEMLE_02388 1e-139 focA P Formate/nitrite transporter
NMLFEMLE_02389 7e-150 sacT K transcriptional antiterminator
NMLFEMLE_02391 0.0 vpr O Belongs to the peptidase S8 family
NMLFEMLE_02392 1.5e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMLFEMLE_02393 1e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NMLFEMLE_02394 2.9e-202 rodA D Belongs to the SEDS family
NMLFEMLE_02395 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NMLFEMLE_02396 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NMLFEMLE_02397 1.6e-89 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NMLFEMLE_02398 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NMLFEMLE_02399 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NMLFEMLE_02400 1e-35 ywzA S membrane
NMLFEMLE_02401 1.3e-303 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NMLFEMLE_02402 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NMLFEMLE_02403 2.4e-47 gtcA S GtrA-like protein
NMLFEMLE_02404 2.2e-122 ywcC K transcriptional regulator
NMLFEMLE_02406 1.1e-47 ywcB S Protein of unknown function, DUF485
NMLFEMLE_02407 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMLFEMLE_02408 8e-45 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NMLFEMLE_02409 2.1e-58 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NMLFEMLE_02410 2.6e-225 ywbN P Dyp-type peroxidase family protein
NMLFEMLE_02411 2.9e-186 ycdO P periplasmic lipoprotein involved in iron transport
NMLFEMLE_02412 4.5e-253 P COG0672 High-affinity Fe2 Pb2 permease
NMLFEMLE_02413 7.2e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NMLFEMLE_02414 8.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NMLFEMLE_02415 4.3e-153 ywbI K Transcriptional regulator
NMLFEMLE_02416 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NMLFEMLE_02417 2.3e-111 ywbG M effector of murein hydrolase
NMLFEMLE_02418 8.1e-208 ywbF EGP Major facilitator Superfamily
NMLFEMLE_02419 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
NMLFEMLE_02420 2e-219 ywbD 2.1.1.191 J Methyltransferase
NMLFEMLE_02421 4.9e-66 ywbC 4.4.1.5 E glyoxalase
NMLFEMLE_02422 2.6e-95 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NMLFEMLE_02423 3.1e-124 ywbB S Protein of unknown function (DUF2711)
NMLFEMLE_02424 5.6e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMLFEMLE_02425 2.3e-273 epr 3.4.21.62 O Belongs to the peptidase S8 family
NMLFEMLE_02426 2e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMLFEMLE_02427 2.1e-149 sacY K transcriptional antiterminator
NMLFEMLE_02428 4.5e-168 gspA M General stress
NMLFEMLE_02429 1.1e-124 ywaF S Integral membrane protein
NMLFEMLE_02430 2.3e-87 ywaE K Transcriptional regulator
NMLFEMLE_02431 3.7e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NMLFEMLE_02432 4.9e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NMLFEMLE_02433 5.3e-92 K Helix-turn-helix XRE-family like proteins
NMLFEMLE_02434 2.1e-48 4.1.1.44 S Carboxymuconolactone decarboxylase family
NMLFEMLE_02435 1e-130 ynfM EGP Major facilitator Superfamily
NMLFEMLE_02436 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NMLFEMLE_02437 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NMLFEMLE_02438 5e-14 S D-Ala-teichoic acid biosynthesis protein
NMLFEMLE_02439 7.4e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMLFEMLE_02440 1.2e-232 dltB M membrane protein involved in D-alanine export
NMLFEMLE_02441 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMLFEMLE_02442 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NMLFEMLE_02443 2.8e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NMLFEMLE_02444 6.9e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NMLFEMLE_02445 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NMLFEMLE_02446 1.9e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NMLFEMLE_02447 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMLFEMLE_02448 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NMLFEMLE_02449 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NMLFEMLE_02450 1.1e-19 yxzF
NMLFEMLE_02451 2.9e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NMLFEMLE_02452 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NMLFEMLE_02453 3e-210 yxlH EGP Major facilitator Superfamily
NMLFEMLE_02454 2.8e-137 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NMLFEMLE_02455 8.5e-87 yxlF V ABC transporter, ATP-binding protein
NMLFEMLE_02456 3.6e-64 yxlF V ABC transporter, ATP-binding protein
NMLFEMLE_02457 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
NMLFEMLE_02458 1.8e-12
NMLFEMLE_02459 1.9e-47 yxlC S Family of unknown function (DUF5345)
NMLFEMLE_02460 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NMLFEMLE_02461 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NMLFEMLE_02462 7.7e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NMLFEMLE_02463 0.0 cydD V ATP-binding protein
NMLFEMLE_02464 3.2e-248 cydD V ATP-binding
NMLFEMLE_02465 1.8e-48 cydD V ATP-binding
NMLFEMLE_02466 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NMLFEMLE_02467 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
NMLFEMLE_02468 2.1e-228 cimH C COG3493 Na citrate symporter
NMLFEMLE_02469 1.3e-307 3.4.24.84 O Peptidase family M48
NMLFEMLE_02471 4.7e-154 yxkH G Polysaccharide deacetylase
NMLFEMLE_02472 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NMLFEMLE_02473 5.4e-164 lrp QT PucR C-terminal helix-turn-helix domain
NMLFEMLE_02474 2e-269 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMLFEMLE_02475 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMLFEMLE_02476 4.4e-137
NMLFEMLE_02477 5.7e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NMLFEMLE_02478 7.7e-77 S Protein of unknown function (DUF1453)
NMLFEMLE_02479 5.9e-190 yxjM T Signal transduction histidine kinase
NMLFEMLE_02480 7.8e-112 K helix_turn_helix, Lux Regulon
NMLFEMLE_02481 9.5e-201 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NMLFEMLE_02484 7.1e-86 yxjI S LURP-one-related
NMLFEMLE_02485 2.3e-220 yxjG 2.1.1.14 E Methionine synthase
NMLFEMLE_02486 1.7e-218 yxjG 2.1.1.14 E Methionine synthase
NMLFEMLE_02487 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NMLFEMLE_02488 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NMLFEMLE_02489 2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NMLFEMLE_02490 2.2e-252 yxjC EG COG2610 H gluconate symporter and related permeases
NMLFEMLE_02491 9.6e-155 rlmA 2.1.1.187 Q Methyltransferase domain
NMLFEMLE_02492 1.2e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMLFEMLE_02493 9.8e-102 T Domain of unknown function (DUF4163)
NMLFEMLE_02494 3e-47 yxiS
NMLFEMLE_02495 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NMLFEMLE_02496 6.6e-224 citH C Citrate transporter
NMLFEMLE_02497 5e-144 exoK GH16 M licheninase activity
NMLFEMLE_02498 8.3e-151 licT K transcriptional antiterminator
NMLFEMLE_02499 1.5e-110
NMLFEMLE_02500 5.7e-101 yxiO S COG2270 Permeases of the major facilitator superfamily
NMLFEMLE_02501 4.9e-117 yxiO S COG2270 Permeases of the major facilitator superfamily
NMLFEMLE_02502 2.1e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NMLFEMLE_02503 8.9e-212 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NMLFEMLE_02506 4.7e-40 yxiJ S YxiJ-like protein
NMLFEMLE_02507 6.3e-82 yxiI S Protein of unknown function (DUF2716)
NMLFEMLE_02508 3.3e-139
NMLFEMLE_02509 5.1e-69 yxiG
NMLFEMLE_02510 7.3e-59
NMLFEMLE_02511 3.8e-84
NMLFEMLE_02512 1.5e-71 yxxG
NMLFEMLE_02513 0.0 wapA M COG3209 Rhs family protein
NMLFEMLE_02514 2.5e-164 yxxF EG EamA-like transporter family
NMLFEMLE_02515 1.2e-56 yxiE T Belongs to the universal stress protein A family
NMLFEMLE_02516 2.1e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMLFEMLE_02517 1.5e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMLFEMLE_02518 2.2e-48
NMLFEMLE_02519 2.9e-78 S SMI1 / KNR4 family
NMLFEMLE_02520 2.2e-56 S nuclease activity
NMLFEMLE_02521 9.2e-145 S nuclease activity
NMLFEMLE_02523 7.3e-19 S Protein conserved in bacteria
NMLFEMLE_02525 3.5e-126 S nuclease activity
NMLFEMLE_02526 1.4e-38 yxiC S Family of unknown function (DUF5344)
NMLFEMLE_02527 5.1e-20 S Domain of unknown function (DUF5082)
NMLFEMLE_02528 1.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NMLFEMLE_02529 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NMLFEMLE_02530 4.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
NMLFEMLE_02531 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NMLFEMLE_02532 7e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NMLFEMLE_02533 6.3e-64 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NMLFEMLE_02534 2.5e-71 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NMLFEMLE_02535 2.6e-250 lysP E amino acid
NMLFEMLE_02536 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NMLFEMLE_02537 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMLFEMLE_02538 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NMLFEMLE_02539 2.3e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NMLFEMLE_02540 4.4e-152 yxxB S Domain of Unknown Function (DUF1206)
NMLFEMLE_02541 1.4e-198 eutH E Ethanolamine utilisation protein, EutH
NMLFEMLE_02542 1.6e-70 yxeQ S MmgE/PrpD family
NMLFEMLE_02543 6.2e-136 yxeQ S MmgE/PrpD family
NMLFEMLE_02544 6.1e-213 yxeP 3.5.1.47 E hydrolase activity
NMLFEMLE_02545 5.9e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NMLFEMLE_02546 1.2e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
NMLFEMLE_02547 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
NMLFEMLE_02548 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMLFEMLE_02549 6.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMLFEMLE_02550 7.7e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NMLFEMLE_02551 1.8e-150 yidA S hydrolases of the HAD superfamily
NMLFEMLE_02554 1.3e-20 yxeE
NMLFEMLE_02555 5.6e-16 yxeD
NMLFEMLE_02556 8.5e-69
NMLFEMLE_02557 6.6e-176 fhuD P ABC transporter
NMLFEMLE_02558 3.4e-58 yxeA S Protein of unknown function (DUF1093)
NMLFEMLE_02559 0.0 yxdM V ABC transporter (permease)
NMLFEMLE_02560 9.4e-141 yxdL V ABC transporter, ATP-binding protein
NMLFEMLE_02561 3.4e-180 T PhoQ Sensor
NMLFEMLE_02562 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMLFEMLE_02563 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NMLFEMLE_02564 1.6e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NMLFEMLE_02565 8.6e-167 iolH G Xylose isomerase-like TIM barrel
NMLFEMLE_02566 8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NMLFEMLE_02567 2.1e-233 iolF EGP Major facilitator Superfamily
NMLFEMLE_02568 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NMLFEMLE_02569 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NMLFEMLE_02570 7.1e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NMLFEMLE_02571 3.5e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NMLFEMLE_02572 3.9e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMLFEMLE_02573 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NMLFEMLE_02574 8.3e-176 iolS C Aldo keto reductase
NMLFEMLE_02576 8.3e-48 yxcD S Protein of unknown function (DUF2653)
NMLFEMLE_02577 9.6e-245 csbC EGP Major facilitator Superfamily
NMLFEMLE_02578 0.0 htpG O Molecular chaperone. Has ATPase activity
NMLFEMLE_02580 1e-148 IQ Enoyl-(Acyl carrier protein) reductase
NMLFEMLE_02581 1.7e-207 yxbF K Bacterial regulatory proteins, tetR family
NMLFEMLE_02582 2.4e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NMLFEMLE_02583 6.3e-31 yxaI S membrane protein domain
NMLFEMLE_02584 9.9e-92 S PQQ-like domain
NMLFEMLE_02585 1.2e-59 S Family of unknown function (DUF5391)
NMLFEMLE_02586 1.4e-75 yxaI S membrane protein domain
NMLFEMLE_02587 1.1e-223 P Protein of unknown function (DUF418)
NMLFEMLE_02588 2.4e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
NMLFEMLE_02589 7.1e-101 yxaF K Transcriptional regulator
NMLFEMLE_02590 7.3e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMLFEMLE_02591 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NMLFEMLE_02592 5.2e-50 S LrgA family
NMLFEMLE_02593 2.6e-118 yxaC M effector of murein hydrolase
NMLFEMLE_02594 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
NMLFEMLE_02595 5.4e-156 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NMLFEMLE_02596 1.1e-30 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NMLFEMLE_02597 2.1e-126 gntR K transcriptional
NMLFEMLE_02598 1.1e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NMLFEMLE_02599 1.1e-17 gntP EG COG2610 H gluconate symporter and related permeases
NMLFEMLE_02600 6.1e-197 gntP EG COG2610 H gluconate symporter and related permeases
NMLFEMLE_02601 2.5e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NMLFEMLE_02602 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NMLFEMLE_02603 3.8e-287 ahpF O Alkyl hydroperoxide reductase
NMLFEMLE_02605 2.7e-45 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
NMLFEMLE_02606 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NMLFEMLE_02607 4.9e-81 dam2 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
NMLFEMLE_02608 8.3e-52 K DNA binding
NMLFEMLE_02609 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NMLFEMLE_02610 1.1e-09 S YyzF-like protein
NMLFEMLE_02611 1e-69
NMLFEMLE_02612 9.6e-166 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NMLFEMLE_02613 4.3e-55 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NMLFEMLE_02615 5.7e-31 yycQ S Protein of unknown function (DUF2651)
NMLFEMLE_02616 3.1e-204 yycP
NMLFEMLE_02617 3.8e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NMLFEMLE_02618 5.8e-85 yycN 2.3.1.128 K Acetyltransferase
NMLFEMLE_02619 9.4e-154 S aspartate phosphatase
NMLFEMLE_02621 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NMLFEMLE_02622 1.3e-260 rocE E amino acid
NMLFEMLE_02623 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NMLFEMLE_02624 7.4e-16
NMLFEMLE_02625 9.6e-95
NMLFEMLE_02626 5.1e-40 S Sporulation delaying protein SdpA
NMLFEMLE_02627 1.1e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NMLFEMLE_02628 1.5e-40 sdpR K transcriptional
NMLFEMLE_02629 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NMLFEMLE_02630 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMLFEMLE_02631 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NMLFEMLE_02632 7.3e-155 yycI S protein conserved in bacteria
NMLFEMLE_02633 3.6e-260 yycH S protein conserved in bacteria
NMLFEMLE_02634 0.0 vicK 2.7.13.3 T Histidine kinase
NMLFEMLE_02635 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMLFEMLE_02640 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NMLFEMLE_02641 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMLFEMLE_02642 1.2e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NMLFEMLE_02643 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NMLFEMLE_02645 1.9e-15 yycC K YycC-like protein
NMLFEMLE_02646 8.4e-221 yeaN P COG2807 Cyanate permease
NMLFEMLE_02647 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NMLFEMLE_02648 2.2e-73 rplI J binds to the 23S rRNA
NMLFEMLE_02649 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NMLFEMLE_02650 3.2e-159 yybS S membrane
NMLFEMLE_02652 3.3e-83 cotF M Spore coat protein
NMLFEMLE_02653 7.5e-67 ydeP3 K Transcriptional regulator
NMLFEMLE_02654 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NMLFEMLE_02655 1.5e-58
NMLFEMLE_02657 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NMLFEMLE_02658 6.3e-110 K TipAS antibiotic-recognition domain
NMLFEMLE_02659 1.1e-123
NMLFEMLE_02660 2.9e-66 yybH S SnoaL-like domain
NMLFEMLE_02661 1.6e-122 yybG S Pentapeptide repeat-containing protein
NMLFEMLE_02662 3.1e-215 ynfM EGP Major facilitator Superfamily
NMLFEMLE_02663 6.9e-164 yybE K Transcriptional regulator
NMLFEMLE_02664 5.5e-77 yjcF S Acetyltransferase (GNAT) domain
NMLFEMLE_02665 2.3e-73 yybC
NMLFEMLE_02666 7.3e-126 S Metallo-beta-lactamase superfamily
NMLFEMLE_02667 5.6e-77 yybA 2.3.1.57 K transcriptional
NMLFEMLE_02668 2e-71 yjcF S Acetyltransferase (GNAT) domain
NMLFEMLE_02669 5.5e-96 yyaS S Membrane
NMLFEMLE_02670 1.6e-91 yyaR K Acetyltransferase (GNAT) domain
NMLFEMLE_02671 1.3e-65 yyaQ S YjbR
NMLFEMLE_02672 2.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
NMLFEMLE_02673 2.8e-38 tetL EGP Major facilitator Superfamily
NMLFEMLE_02674 2.4e-79 tetL EGP Major facilitator Superfamily
NMLFEMLE_02675 2.1e-78 tetL EGP Major facilitator Superfamily
NMLFEMLE_02676 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
NMLFEMLE_02677 1.5e-60 yyaN K MerR HTH family regulatory protein
NMLFEMLE_02678 3.5e-152 yyaM EG EamA-like transporter family
NMLFEMLE_02679 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NMLFEMLE_02680 8e-168 yyaK S CAAX protease self-immunity
NMLFEMLE_02681 3.3e-125 EGP Major facilitator superfamily
NMLFEMLE_02682 8.1e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NMLFEMLE_02683 8.9e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMLFEMLE_02684 3.6e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NMLFEMLE_02685 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
NMLFEMLE_02686 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NMLFEMLE_02687 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NMLFEMLE_02688 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NMLFEMLE_02689 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NMLFEMLE_02690 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMLFEMLE_02691 2.3e-33 yyzM S protein conserved in bacteria
NMLFEMLE_02692 8.1e-177 yyaD S Membrane
NMLFEMLE_02693 2.8e-111 yyaC S Sporulation protein YyaC
NMLFEMLE_02694 2.1e-149 spo0J K Belongs to the ParB family
NMLFEMLE_02695 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NMLFEMLE_02696 1.6e-73 S Bacterial PH domain
NMLFEMLE_02697 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NMLFEMLE_02698 5.3e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NMLFEMLE_02699 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NMLFEMLE_02700 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NMLFEMLE_02701 6.5e-108 jag S single-stranded nucleic acid binding R3H
NMLFEMLE_02702 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMLFEMLE_02703 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NMLFEMLE_02704 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NMLFEMLE_02705 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NMLFEMLE_02706 2.4e-33 yaaA S S4 domain
NMLFEMLE_02707 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NMLFEMLE_02708 1.8e-37 yaaB S Domain of unknown function (DUF370)
NMLFEMLE_02709 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMLFEMLE_02710 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMLFEMLE_02711 3.4e-39 S COG NOG14552 non supervised orthologous group
NMLFEMLE_02714 1e-181 yaaC S YaaC-like Protein
NMLFEMLE_02715 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NMLFEMLE_02716 9.8e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NMLFEMLE_02717 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NMLFEMLE_02718 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NMLFEMLE_02719 1.2e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NMLFEMLE_02721 6.3e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NMLFEMLE_02722 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NMLFEMLE_02723 1.4e-213 yaaH M Glycoside Hydrolase Family
NMLFEMLE_02724 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
NMLFEMLE_02725 3.3e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NMLFEMLE_02726 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMLFEMLE_02727 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NMLFEMLE_02728 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NMLFEMLE_02729 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NMLFEMLE_02730 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NMLFEMLE_02731 3.4e-39 S COG NOG14552 non supervised orthologous group
NMLFEMLE_02734 3.4e-31 csfB S Inhibitor of sigma-G Gin
NMLFEMLE_02735 2.4e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NMLFEMLE_02736 9.9e-203 yaaN P Belongs to the TelA family
NMLFEMLE_02737 5.1e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NMLFEMLE_02738 6.9e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NMLFEMLE_02739 2.2e-54 yaaQ S protein conserved in bacteria
NMLFEMLE_02740 5.9e-71 yaaR S protein conserved in bacteria
NMLFEMLE_02741 1.1e-181 holB 2.7.7.7 L DNA polymerase III
NMLFEMLE_02742 6.1e-146 yaaT S stage 0 sporulation protein
NMLFEMLE_02743 4.8e-31 yabA L Involved in initiation control of chromosome replication
NMLFEMLE_02744 7.2e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
NMLFEMLE_02745 1.5e-49 yazA L endonuclease containing a URI domain
NMLFEMLE_02746 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NMLFEMLE_02747 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NMLFEMLE_02748 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMLFEMLE_02749 3.4e-143 tatD L hydrolase, TatD
NMLFEMLE_02750 2e-167 rpfB GH23 T protein conserved in bacteria
NMLFEMLE_02751 7.9e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NMLFEMLE_02752 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NMLFEMLE_02753 6.2e-136 yabG S peptidase
NMLFEMLE_02754 7.8e-39 veg S protein conserved in bacteria
NMLFEMLE_02755 8.3e-27 sspF S DNA topological change
NMLFEMLE_02756 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NMLFEMLE_02757 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NMLFEMLE_02758 1.1e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NMLFEMLE_02759 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NMLFEMLE_02760 7.3e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NMLFEMLE_02761 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMLFEMLE_02762 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NMLFEMLE_02763 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NMLFEMLE_02764 2.4e-39 yabK S Peptide ABC transporter permease
NMLFEMLE_02765 1.3e-91 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NMLFEMLE_02766 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NMLFEMLE_02767 1.5e-92 spoVT K stage V sporulation protein
NMLFEMLE_02768 6.9e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMLFEMLE_02769 2.7e-58 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NMLFEMLE_02770 7e-163 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NMLFEMLE_02771 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NMLFEMLE_02772 1.5e-49 yabP S Sporulation protein YabP
NMLFEMLE_02773 4.3e-107 yabQ S spore cortex biosynthesis protein
NMLFEMLE_02774 1.1e-44 divIC D Septum formation initiator
NMLFEMLE_02775 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NMLFEMLE_02778 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NMLFEMLE_02779 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NMLFEMLE_02780 6.2e-174 KLT serine threonine protein kinase
NMLFEMLE_02781 8e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NMLFEMLE_02782 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NMLFEMLE_02783 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NMLFEMLE_02784 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NMLFEMLE_02785 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NMLFEMLE_02786 1.3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NMLFEMLE_02787 1.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NMLFEMLE_02788 3.5e-266 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NMLFEMLE_02789 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NMLFEMLE_02790 2.3e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NMLFEMLE_02791 2.9e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NMLFEMLE_02792 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NMLFEMLE_02793 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NMLFEMLE_02794 4.1e-30 yazB K transcriptional
NMLFEMLE_02795 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMLFEMLE_02796 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NMLFEMLE_02797 3.4e-39 S COG NOG14552 non supervised orthologous group
NMLFEMLE_02802 2e-08
NMLFEMLE_02807 3.4e-39 S COG NOG14552 non supervised orthologous group
NMLFEMLE_02808 2.9e-76 ctsR K Belongs to the CtsR family
NMLFEMLE_02809 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NMLFEMLE_02810 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NMLFEMLE_02811 0.0 clpC O Belongs to the ClpA ClpB family
NMLFEMLE_02812 3.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NMLFEMLE_02813 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NMLFEMLE_02814 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NMLFEMLE_02815 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NMLFEMLE_02816 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NMLFEMLE_02817 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NMLFEMLE_02818 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
NMLFEMLE_02819 2.1e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMLFEMLE_02820 1.2e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NMLFEMLE_02821 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMLFEMLE_02822 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NMLFEMLE_02823 2.8e-115 sigH K Belongs to the sigma-70 factor family
NMLFEMLE_02824 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NMLFEMLE_02825 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NMLFEMLE_02826 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NMLFEMLE_02827 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NMLFEMLE_02828 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NMLFEMLE_02829 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NMLFEMLE_02830 3.1e-107 rsmC 2.1.1.172 J Methyltransferase
NMLFEMLE_02831 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMLFEMLE_02832 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMLFEMLE_02833 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NMLFEMLE_02834 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NMLFEMLE_02835 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NMLFEMLE_02836 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NMLFEMLE_02837 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NMLFEMLE_02838 1.1e-61 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NMLFEMLE_02839 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NMLFEMLE_02840 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NMLFEMLE_02841 3e-105 rplD J Forms part of the polypeptide exit tunnel
NMLFEMLE_02842 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NMLFEMLE_02843 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NMLFEMLE_02844 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NMLFEMLE_02845 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NMLFEMLE_02846 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NMLFEMLE_02847 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NMLFEMLE_02848 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NMLFEMLE_02849 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NMLFEMLE_02850 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NMLFEMLE_02851 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NMLFEMLE_02852 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NMLFEMLE_02853 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMLFEMLE_02854 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NMLFEMLE_02855 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NMLFEMLE_02856 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NMLFEMLE_02857 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NMLFEMLE_02858 1.9e-23 rpmD J Ribosomal protein L30
NMLFEMLE_02859 1.8e-72 rplO J binds to the 23S rRNA
NMLFEMLE_02860 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NMLFEMLE_02861 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NMLFEMLE_02862 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NMLFEMLE_02863 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NMLFEMLE_02864 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NMLFEMLE_02865 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NMLFEMLE_02866 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NMLFEMLE_02867 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMLFEMLE_02868 3.6e-58 rplQ J Ribosomal protein L17
NMLFEMLE_02869 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMLFEMLE_02870 3.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMLFEMLE_02871 3e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMLFEMLE_02872 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NMLFEMLE_02873 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NMLFEMLE_02874 1.8e-63 rpsI J Belongs to the universal ribosomal protein uS9 family
NMLFEMLE_02875 2.4e-144 ybaJ Q Methyltransferase domain
NMLFEMLE_02876 9.1e-64 ybaK S Protein of unknown function (DUF2521)
NMLFEMLE_02877 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMLFEMLE_02878 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NMLFEMLE_02879 1.2e-84 gerD
NMLFEMLE_02880 2.5e-49 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NMLFEMLE_02881 1e-31 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NMLFEMLE_02882 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
NMLFEMLE_02883 3.4e-39 S COG NOG14552 non supervised orthologous group
NMLFEMLE_02886 2e-81 L Phage integrase, N-terminal SAM-like domain
NMLFEMLE_02887 4.8e-35 xkdA E IrrE N-terminal-like domain
NMLFEMLE_02888 4.3e-13
NMLFEMLE_02890 1.5e-18 K Cro/C1-type HTH DNA-binding domain
NMLFEMLE_02891 4.9e-16 ropB K sequence-specific DNA binding
NMLFEMLE_02892 3.9e-11 S Helix-turn-helix domain
NMLFEMLE_02893 4.8e-43
NMLFEMLE_02897 1e-170 D nuclear chromosome segregation
NMLFEMLE_02898 1.2e-87 bet L RecT family
NMLFEMLE_02899 4.1e-103 S Metallo-beta-lactamase superfamily
NMLFEMLE_02901 3.1e-27 L primosome component and related proteins
NMLFEMLE_02902 3.8e-07 S Loader and inhibitor of phage G40P
NMLFEMLE_02903 1.3e-179 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NMLFEMLE_02906 3.5e-48 3.1.22.4
NMLFEMLE_02907 1.3e-69
NMLFEMLE_02911 3.2e-30
NMLFEMLE_02914 1.1e-16 S Putative phage abortive infection protein
NMLFEMLE_02915 2.2e-37
NMLFEMLE_02916 1.7e-06 L PFAM Integrase catalytic
NMLFEMLE_02921 5.2e-57 K DNA binding
NMLFEMLE_02922 3e-126 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NMLFEMLE_02924 2.8e-30
NMLFEMLE_02925 1.4e-73
NMLFEMLE_02926 1.1e-71
NMLFEMLE_02927 2.5e-234 S phage terminase, large subunit
NMLFEMLE_02928 1.2e-251 yqbA S portal protein
NMLFEMLE_02929 1.8e-146 S Phage Mu protein F like protein
NMLFEMLE_02931 9.8e-97 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NMLFEMLE_02932 9.6e-148 xkdG S Phage capsid family
NMLFEMLE_02933 3.9e-25 S YqbF, hypothetical protein domain
NMLFEMLE_02934 2e-46 S Protein of unknown function (DUF3199)
NMLFEMLE_02935 8.8e-57 yqbH S Domain of unknown function (DUF3599)
NMLFEMLE_02936 1.6e-85 S Bacteriophage HK97-gp10, putative tail-component
NMLFEMLE_02937 4.6e-76
NMLFEMLE_02938 2.7e-25
NMLFEMLE_02939 3.3e-245 xkdK S Phage tail sheath C-terminal domain
NMLFEMLE_02940 7.4e-74 xkdM S Phage tail tube protein
NMLFEMLE_02941 2.6e-66 S Phage XkdN-like tail assembly chaperone protein, TAC
NMLFEMLE_02942 0.0 xkdO L Transglycosylase SLT domain
NMLFEMLE_02943 6e-110 xkdP S Lysin motif
NMLFEMLE_02944 6.1e-177 yqbQ 3.2.1.96 G NLP P60 protein
NMLFEMLE_02945 7.2e-32 xkdR S Protein of unknown function (DUF2577)
NMLFEMLE_02946 7.6e-68 xkdS S Protein of unknown function (DUF2634)
NMLFEMLE_02947 7.4e-181 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NMLFEMLE_02948 6.2e-97 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NMLFEMLE_02949 2.5e-35
NMLFEMLE_02950 2.8e-172
NMLFEMLE_02951 1.1e-45 xkdW S XkdW protein
NMLFEMLE_02952 4.6e-21
NMLFEMLE_02953 1.1e-148 xepA
NMLFEMLE_02954 2.8e-34 xhlA S Haemolysin XhlA
NMLFEMLE_02955 2.7e-31 xhlB S SPP1 phage holin
NMLFEMLE_02956 1.5e-122 xlyB 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NMLFEMLE_02957 5.6e-56 S SMI1-KNR4 cell-wall
NMLFEMLE_02958 7.8e-276 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMLFEMLE_02959 3.2e-190 S Histidine kinase
NMLFEMLE_02961 3.1e-13
NMLFEMLE_02962 1.5e-09 K Transcriptional regulator
NMLFEMLE_02963 5.1e-10 lexA 3.4.21.88 KT domain protein
NMLFEMLE_02964 2e-08
NMLFEMLE_02968 3.4e-39 S COG NOG14552 non supervised orthologous group
NMLFEMLE_02969 3.4e-39 S COG NOG14552 non supervised orthologous group
NMLFEMLE_02970 1.5e-248 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NMLFEMLE_02971 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
NMLFEMLE_02972 4.1e-141 ybbA S Putative esterase
NMLFEMLE_02973 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMLFEMLE_02974 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMLFEMLE_02975 1.4e-165 feuA P Iron-uptake system-binding protein
NMLFEMLE_02976 7.7e-307 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NMLFEMLE_02977 4.9e-240 ybbC 3.2.1.52 S protein conserved in bacteria
NMLFEMLE_02978 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NMLFEMLE_02979 5.9e-252 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NMLFEMLE_02980 1.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMLFEMLE_02981 5.1e-148 ybbH K transcriptional
NMLFEMLE_02982 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NMLFEMLE_02983 1.9e-86 ybbJ J acetyltransferase
NMLFEMLE_02984 1.3e-57 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NMLFEMLE_02985 8.2e-10 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NMLFEMLE_02991 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NMLFEMLE_02992 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NMLFEMLE_02993 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMLFEMLE_02994 3e-225 ybbR S protein conserved in bacteria
NMLFEMLE_02995 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NMLFEMLE_02996 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NMLFEMLE_02997 7.9e-171 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NMLFEMLE_02998 5.8e-120 adaA 3.2.2.21 K Transcriptional regulator
NMLFEMLE_02999 2.5e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NMLFEMLE_03000 1e-41 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NMLFEMLE_03001 2.1e-213 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NMLFEMLE_03002 0.0 ybcC S Belongs to the UPF0753 family
NMLFEMLE_03003 3e-90 can 4.2.1.1 P carbonic anhydrase
NMLFEMLE_03004 1.9e-46
NMLFEMLE_03005 3.2e-59 ybcI S Uncharacterized conserved protein (DUF2294)
NMLFEMLE_03006 9.6e-49 ybzH K Helix-turn-helix domain
NMLFEMLE_03007 2.5e-105 ybcL EGP Major facilitator Superfamily
NMLFEMLE_03008 2.9e-79 ybcL EGP Major facilitator Superfamily
NMLFEMLE_03010 2.8e-33 O Subtilase family
NMLFEMLE_03011 2.5e-123 spaB S Lantibiotic dehydratase, C terminus
NMLFEMLE_03012 3.7e-60 spaC1 V Lanthionine synthetase C-like protein
NMLFEMLE_03014 9.5e-48 msbA2 3.6.3.44 V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMLFEMLE_03015 7.3e-77 msbA2 3.6.3.44 V ABC transporter
NMLFEMLE_03016 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMLFEMLE_03017 3.5e-98 T Transcriptional regulatory protein, C terminal
NMLFEMLE_03018 2.9e-171 T His Kinase A (phospho-acceptor) domain
NMLFEMLE_03020 8.8e-139 KLT Protein tyrosine kinase
NMLFEMLE_03021 1.7e-151 ybdN
NMLFEMLE_03022 4.4e-214 ybdO S Domain of unknown function (DUF4885)
NMLFEMLE_03023 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NMLFEMLE_03024 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
NMLFEMLE_03025 5.4e-29 ybxH S Family of unknown function (DUF5370)
NMLFEMLE_03026 5.9e-35 ybxI 3.5.2.6 V beta-lactamase
NMLFEMLE_03027 2.7e-84 ybxI 3.5.2.6 V beta-lactamase
NMLFEMLE_03028 7.6e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NMLFEMLE_03029 4.9e-41 ybyB
NMLFEMLE_03030 8.8e-290 ybeC E amino acid
NMLFEMLE_03031 4.1e-49 M PFAM Glycosyl transferase family 2
NMLFEMLE_03032 1.8e-159 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NMLFEMLE_03033 7.3e-258 glpT G -transporter
NMLFEMLE_03034 1.5e-34 S Protein of unknown function (DUF2651)
NMLFEMLE_03035 2.2e-168 ybfA 3.4.15.5 K FR47-like protein
NMLFEMLE_03036 2.5e-223 ybfB G COG0477 Permeases of the major facilitator superfamily
NMLFEMLE_03037 3.2e-136 ybfH EG EamA-like transporter family
NMLFEMLE_03039 9.7e-144 msmR K AraC-like ligand binding domain
NMLFEMLE_03040 2.3e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NMLFEMLE_03041 1.5e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NMLFEMLE_03043 1.9e-166 S Alpha/beta hydrolase family
NMLFEMLE_03044 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NMLFEMLE_03045 2.7e-85 ybfM S SNARE associated Golgi protein
NMLFEMLE_03046 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NMLFEMLE_03047 1.3e-44 ybfN
NMLFEMLE_03048 2.1e-252 S Erythromycin esterase
NMLFEMLE_03049 8.6e-192 yceA S Belongs to the UPF0176 family
NMLFEMLE_03050 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMLFEMLE_03051 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMLFEMLE_03052 8e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NMLFEMLE_03053 4.9e-128 K UTRA
NMLFEMLE_03055 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NMLFEMLE_03056 7.5e-261 mmuP E amino acid
NMLFEMLE_03057 6.7e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NMLFEMLE_03058 2.8e-255 agcS E Sodium alanine symporter
NMLFEMLE_03059 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
NMLFEMLE_03060 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
NMLFEMLE_03061 9e-170 glnL T Regulator
NMLFEMLE_03062 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NMLFEMLE_03063 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMLFEMLE_03064 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NMLFEMLE_03065 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NMLFEMLE_03066 2.1e-123 ycbG K FCD
NMLFEMLE_03067 1.9e-27 garD 4.2.1.42, 4.2.1.7 G Altronate
NMLFEMLE_03068 1.6e-257 garD 4.2.1.42, 4.2.1.7 G Altronate
NMLFEMLE_03069 3.1e-175 ycbJ S Macrolide 2'-phosphotransferase
NMLFEMLE_03070 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NMLFEMLE_03071 3.8e-168 eamA1 EG spore germination
NMLFEMLE_03072 8.1e-112 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMLFEMLE_03073 5.4e-167 T PhoQ Sensor
NMLFEMLE_03074 5e-165 ycbN V ABC transporter, ATP-binding protein
NMLFEMLE_03075 7.4e-113 S ABC-2 family transporter protein
NMLFEMLE_03076 1.2e-51 ycbP S Protein of unknown function (DUF2512)
NMLFEMLE_03077 2.2e-78 sleB 3.5.1.28 M Cell wall
NMLFEMLE_03078 9.5e-135 ycbR T vWA found in TerF C terminus
NMLFEMLE_03079 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NMLFEMLE_03080 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NMLFEMLE_03081 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NMLFEMLE_03082 1.7e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NMLFEMLE_03083 6.6e-204 ycbU E Selenocysteine lyase
NMLFEMLE_03084 7.9e-226 lmrB EGP the major facilitator superfamily
NMLFEMLE_03085 7e-101 yxaF K Transcriptional regulator
NMLFEMLE_03086 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NMLFEMLE_03087 4.7e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NMLFEMLE_03088 3.4e-59 S RDD family
NMLFEMLE_03089 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
NMLFEMLE_03090 5.6e-159 2.7.13.3 T GHKL domain
NMLFEMLE_03091 1.2e-126 lytR_2 T LytTr DNA-binding domain
NMLFEMLE_03092 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NMLFEMLE_03093 4.5e-203 natB CP ABC-2 family transporter protein
NMLFEMLE_03094 4.6e-174 yccK C Aldo keto reductase
NMLFEMLE_03095 6.6e-177 ycdA S Domain of unknown function (DUF5105)
NMLFEMLE_03096 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NMLFEMLE_03097 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NMLFEMLE_03098 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
NMLFEMLE_03099 5.5e-174 S response regulator aspartate phosphatase
NMLFEMLE_03100 4.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
NMLFEMLE_03101 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NMLFEMLE_03102 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
NMLFEMLE_03103 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NMLFEMLE_03104 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NMLFEMLE_03105 4.2e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMLFEMLE_03106 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NMLFEMLE_03107 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NMLFEMLE_03108 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
NMLFEMLE_03109 1.4e-136 terC P Protein of unknown function (DUF475)
NMLFEMLE_03110 0.0 yceG S Putative component of 'biosynthetic module'
NMLFEMLE_03111 2e-192 yceH P Belongs to the TelA family
NMLFEMLE_03112 6.6e-218 naiP P Uncharacterised MFS-type transporter YbfB
NMLFEMLE_03113 1.5e-178 yceJ EGP Uncharacterised MFS-type transporter YbfB
NMLFEMLE_03114 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NMLFEMLE_03115 5.1e-229 proV 3.6.3.32 E glycine betaine
NMLFEMLE_03116 1.3e-127 opuAB P glycine betaine
NMLFEMLE_03117 1.5e-163 opuAC E glycine betaine
NMLFEMLE_03118 1.1e-217 amhX S amidohydrolase
NMLFEMLE_03119 3.3e-256 ycgA S Membrane
NMLFEMLE_03120 1.1e-98 ycgB
NMLFEMLE_03121 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NMLFEMLE_03122 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NMLFEMLE_03123 6.5e-293 lctP C L-lactate permease
NMLFEMLE_03124 6.2e-269 mdr EGP Major facilitator Superfamily
NMLFEMLE_03125 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
NMLFEMLE_03126 1.6e-50 ycgF E Lysine exporter protein LysE YggA
NMLFEMLE_03127 1e-41 ycgF E Lysine exporter protein LysE YggA
NMLFEMLE_03128 1.2e-151 yqcI S YqcI/YcgG family
NMLFEMLE_03129 1.4e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NMLFEMLE_03130 2.4e-112 ycgI S Domain of unknown function (DUF1989)
NMLFEMLE_03131 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NMLFEMLE_03132 2.5e-109 tmrB S AAA domain
NMLFEMLE_03133 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NMLFEMLE_03134 1.7e-142 yafE Q ubiE/COQ5 methyltransferase family
NMLFEMLE_03135 1.2e-177 oxyR3 K LysR substrate binding domain
NMLFEMLE_03136 4.2e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NMLFEMLE_03137 2.9e-145 ycgL S Predicted nucleotidyltransferase
NMLFEMLE_03138 1.1e-169 ycgM E Proline dehydrogenase
NMLFEMLE_03139 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NMLFEMLE_03140 3.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMLFEMLE_03141 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NMLFEMLE_03142 9.1e-145 ycgQ S membrane
NMLFEMLE_03143 9.1e-140 ycgR S permeases
NMLFEMLE_03144 1.6e-157 I alpha/beta hydrolase fold
NMLFEMLE_03145 3.1e-164 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NMLFEMLE_03146 3.2e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NMLFEMLE_03147 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NMLFEMLE_03148 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NMLFEMLE_03149 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMLFEMLE_03150 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NMLFEMLE_03151 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
NMLFEMLE_03152 4.3e-169 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NMLFEMLE_03153 7.9e-108 yciB M ErfK YbiS YcfS YnhG
NMLFEMLE_03154 2.4e-84 yciC S GTPases (G3E family)
NMLFEMLE_03155 4.3e-129 yciC S GTPases (G3E family)
NMLFEMLE_03156 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
NMLFEMLE_03157 7.5e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NMLFEMLE_03158 3.3e-45 yckC S membrane
NMLFEMLE_03159 7.8e-52 yckD S Protein of unknown function (DUF2680)
NMLFEMLE_03160 4e-294 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMLFEMLE_03161 6.5e-69 nin S Competence protein J (ComJ)
NMLFEMLE_03162 3e-70 nucA M Deoxyribonuclease NucA/NucB
NMLFEMLE_03163 3.9e-187 tlpC 2.7.13.3 NT chemotaxis protein
NMLFEMLE_03164 1.8e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NMLFEMLE_03165 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NMLFEMLE_03166 1.3e-63 hxlR K transcriptional
NMLFEMLE_03167 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMLFEMLE_03168 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMLFEMLE_03169 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NMLFEMLE_03170 7.5e-140 srfAD Q thioesterase
NMLFEMLE_03171 7e-223 EGP Major Facilitator Superfamily
NMLFEMLE_03172 3.3e-87 S YcxB-like protein
NMLFEMLE_03173 6.4e-160 ycxC EG EamA-like transporter family
NMLFEMLE_03174 6.6e-53 ycxD K GntR family transcriptional regulator
NMLFEMLE_03175 1.1e-175 ycxD K GntR family transcriptional regulator
NMLFEMLE_03176 2.9e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NMLFEMLE_03177 1.7e-114 yczE S membrane
NMLFEMLE_03178 4.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NMLFEMLE_03179 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NMLFEMLE_03180 3.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NMLFEMLE_03181 1.9e-161 bsdA K LysR substrate binding domain
NMLFEMLE_03182 7.6e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NMLFEMLE_03183 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NMLFEMLE_03184 4e-39 bsdD 4.1.1.61 S response to toxic substance
NMLFEMLE_03185 2.5e-80 yclD
NMLFEMLE_03186 2.2e-159 yclE 3.4.11.5 S Alpha beta hydrolase
NMLFEMLE_03187 5.2e-265 dtpT E amino acid peptide transporter
NMLFEMLE_03188 4.1e-309 yclG M Pectate lyase superfamily protein
NMLFEMLE_03190 1.5e-281 gerKA EG Spore germination protein
NMLFEMLE_03191 1.3e-232 gerKC S spore germination
NMLFEMLE_03192 1.7e-199 gerKB F Spore germination protein
NMLFEMLE_03193 1.9e-121 yclH P ABC transporter
NMLFEMLE_03194 1.5e-203 yclI V ABC transporter (permease) YclI
NMLFEMLE_03195 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMLFEMLE_03196 1.5e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NMLFEMLE_03197 2e-70 S aspartate phosphatase
NMLFEMLE_03201 8.3e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
NMLFEMLE_03202 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMLFEMLE_03203 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMLFEMLE_03204 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NMLFEMLE_03205 1.2e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NMLFEMLE_03206 3.2e-251 ycnB EGP Major facilitator Superfamily
NMLFEMLE_03207 2.7e-152 ycnC K Transcriptional regulator
NMLFEMLE_03208 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NMLFEMLE_03209 1.6e-45 ycnE S Monooxygenase
NMLFEMLE_03210 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NMLFEMLE_03211 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMLFEMLE_03212 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMLFEMLE_03213 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMLFEMLE_03214 9e-96 glcU U Glucose uptake
NMLFEMLE_03215 4.1e-24 glcU U Glucose uptake
NMLFEMLE_03216 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMLFEMLE_03217 1.3e-100 ycnI S protein conserved in bacteria
NMLFEMLE_03218 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
NMLFEMLE_03219 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NMLFEMLE_03220 7.3e-56
NMLFEMLE_03221 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NMLFEMLE_03222 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NMLFEMLE_03223 1.8e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NMLFEMLE_03224 1.4e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NMLFEMLE_03225 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NMLFEMLE_03226 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NMLFEMLE_03227 1.4e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NMLFEMLE_03228 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NMLFEMLE_03230 3e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NMLFEMLE_03231 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
NMLFEMLE_03232 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NMLFEMLE_03233 4.8e-148 ycsI S Belongs to the D-glutamate cyclase family
NMLFEMLE_03234 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NMLFEMLE_03235 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NMLFEMLE_03236 3.7e-31 kipR K Transcriptional regulator
NMLFEMLE_03237 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
NMLFEMLE_03239 1.4e-49 yczJ S biosynthesis
NMLFEMLE_03240 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NMLFEMLE_03241 8.3e-173 ydhF S Oxidoreductase
NMLFEMLE_03242 0.0 mtlR K transcriptional regulator, MtlR
NMLFEMLE_03243 1.5e-291 ydaB IQ acyl-CoA ligase
NMLFEMLE_03244 1.7e-97 ydaC Q Methyltransferase domain
NMLFEMLE_03245 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMLFEMLE_03246 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NMLFEMLE_03247 6.1e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMLFEMLE_03248 6.8e-77 ydaG 1.4.3.5 S general stress protein
NMLFEMLE_03249 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NMLFEMLE_03250 3.3e-46 ydzA EGP Major facilitator Superfamily
NMLFEMLE_03251 2.5e-74 lrpC K Transcriptional regulator
NMLFEMLE_03252 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMLFEMLE_03253 1.2e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NMLFEMLE_03254 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
NMLFEMLE_03255 4e-44 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NMLFEMLE_03256 6.9e-142 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NMLFEMLE_03257 4.5e-233 ydaM M Glycosyl transferase family group 2
NMLFEMLE_03258 0.0 ydaN S Bacterial cellulose synthase subunit
NMLFEMLE_03259 0.0 ydaO E amino acid
NMLFEMLE_03260 1.1e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NMLFEMLE_03261 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NMLFEMLE_03262 9.4e-40
NMLFEMLE_03263 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NMLFEMLE_03265 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NMLFEMLE_03266 3.2e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NMLFEMLE_03268 1.5e-55 ydbB G Cupin domain
NMLFEMLE_03269 1.3e-60 ydbC S Domain of unknown function (DUF4937
NMLFEMLE_03270 3.5e-154 ydbD P Catalase
NMLFEMLE_03271 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NMLFEMLE_03272 1.3e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NMLFEMLE_03273 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
NMLFEMLE_03274 1.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMLFEMLE_03275 1.4e-179 ydbI S AI-2E family transporter
NMLFEMLE_03276 1.3e-168 ydbJ V ABC transporter, ATP-binding protein
NMLFEMLE_03277 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NMLFEMLE_03278 2.7e-52 ydbL
NMLFEMLE_03279 1.5e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NMLFEMLE_03280 1.1e-18 S Fur-regulated basic protein B
NMLFEMLE_03281 1.7e-07 S Fur-regulated basic protein A
NMLFEMLE_03282 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMLFEMLE_03283 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NMLFEMLE_03284 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NMLFEMLE_03285 3.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NMLFEMLE_03286 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NMLFEMLE_03287 2.1e-82 ydbS S Bacterial PH domain
NMLFEMLE_03288 2.2e-263 ydbT S Membrane
NMLFEMLE_03289 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NMLFEMLE_03290 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NMLFEMLE_03291 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NMLFEMLE_03292 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMLFEMLE_03293 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NMLFEMLE_03294 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NMLFEMLE_03295 1.3e-143 rsbR T Positive regulator of sigma-B
NMLFEMLE_03296 1.5e-56 rsbS T antagonist
NMLFEMLE_03297 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NMLFEMLE_03298 7.1e-189 rsbU 3.1.3.3 KT phosphatase
NMLFEMLE_03299 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
NMLFEMLE_03300 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NMLFEMLE_03301 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMLFEMLE_03302 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NMLFEMLE_03303 0.0 yhgF K COG2183 Transcriptional accessory protein
NMLFEMLE_03304 8.9e-83 ydcK S Belongs to the SprT family
NMLFEMLE_03313 3.4e-33 K Helix-turn-helix XRE-family like proteins
NMLFEMLE_03314 1.2e-39
NMLFEMLE_03318 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NMLFEMLE_03319 8.7e-30 cspL K Cold shock
NMLFEMLE_03320 2.3e-78 carD K Transcription factor
NMLFEMLE_03321 3.3e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NMLFEMLE_03322 3.6e-165 rhaS5 K AraC-like ligand binding domain
NMLFEMLE_03323 8.3e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NMLFEMLE_03324 2.6e-163 ydeE K AraC family transcriptional regulator
NMLFEMLE_03325 2.4e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMLFEMLE_03326 1.8e-216 ydeG EGP Major facilitator superfamily
NMLFEMLE_03327 1.4e-44 ydeH
NMLFEMLE_03328 3.9e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NMLFEMLE_03329 3.8e-103
NMLFEMLE_03330 1.8e-14 ptsH G PTS HPr component phosphorylation site
NMLFEMLE_03331 3.4e-84 K Transcriptional regulator C-terminal region
NMLFEMLE_03332 3.5e-136 ydeK EG -transporter
NMLFEMLE_03333 6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMLFEMLE_03334 7.1e-74 maoC I N-terminal half of MaoC dehydratase
NMLFEMLE_03335 2.5e-104 ydeN S Serine hydrolase
NMLFEMLE_03336 1.2e-55 K HxlR-like helix-turn-helix
NMLFEMLE_03337 2.1e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NMLFEMLE_03338 9.6e-185 ydeR EGP Major facilitator Superfamily
NMLFEMLE_03339 3.2e-104 ydeS K Transcriptional regulator
NMLFEMLE_03341 2.8e-57 arsR K transcriptional
NMLFEMLE_03342 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NMLFEMLE_03343 1.8e-144 ydfB J GNAT acetyltransferase
NMLFEMLE_03344 1.6e-158 ydfC EG EamA-like transporter family
NMLFEMLE_03345 2.3e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMLFEMLE_03346 1.4e-115 ydfE S Flavin reductase like domain
NMLFEMLE_03347 3.9e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NMLFEMLE_03348 3.4e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NMLFEMLE_03350 9.2e-163 ydfH 2.7.13.3 T Histidine kinase
NMLFEMLE_03351 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMLFEMLE_03352 0.0 ydfJ S drug exporters of the RND superfamily
NMLFEMLE_03353 3.1e-175 S Alpha/beta hydrolase family
NMLFEMLE_03354 8.5e-117 S Protein of unknown function (DUF554)
NMLFEMLE_03355 6.6e-145 K Bacterial transcription activator, effector binding domain
NMLFEMLE_03356 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMLFEMLE_03357 4e-110 ydfN C nitroreductase
NMLFEMLE_03358 1.7e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NMLFEMLE_03359 8.8e-63 mhqP S DoxX
NMLFEMLE_03360 1.6e-55 traF CO Thioredoxin
NMLFEMLE_03361 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NMLFEMLE_03362 6.3e-29
NMLFEMLE_03364 4.4e-118 ydfR S Protein of unknown function (DUF421)
NMLFEMLE_03365 9e-122 ydfS S Protein of unknown function (DUF421)
NMLFEMLE_03366 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
NMLFEMLE_03367 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
NMLFEMLE_03368 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
NMLFEMLE_03369 2.2e-97 K Bacterial regulatory proteins, tetR family
NMLFEMLE_03370 9e-51 S DoxX-like family
NMLFEMLE_03371 4.7e-52 yycN 2.3.1.128 K Acetyltransferase
NMLFEMLE_03372 1e-301 expZ S ABC transporter
NMLFEMLE_03373 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NMLFEMLE_03374 1.1e-89 dinB S DinB family
NMLFEMLE_03375 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
NMLFEMLE_03376 0.0 ydgH S drug exporters of the RND superfamily
NMLFEMLE_03377 8.8e-113 drgA C nitroreductase
NMLFEMLE_03378 7.1e-69 ydgJ K Winged helix DNA-binding domain
NMLFEMLE_03379 2.2e-208 tcaB EGP Major facilitator Superfamily
NMLFEMLE_03380 3.5e-121 ydhB S membrane transporter protein
NMLFEMLE_03381 6.5e-122 ydhC K FCD
NMLFEMLE_03382 2.9e-145 ydhD M Glycosyl hydrolase
NMLFEMLE_03383 6.2e-84 ydhD M Glycosyl hydrolase
NMLFEMLE_03384 3.1e-56 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NMLFEMLE_03385 6.9e-161 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NMLFEMLE_03386 1.9e-124
NMLFEMLE_03387 2.6e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NMLFEMLE_03388 8.7e-68 frataxin S Domain of unknown function (DU1801)
NMLFEMLE_03390 1.9e-83 K Acetyltransferase (GNAT) domain
NMLFEMLE_03391 1.1e-178 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NMLFEMLE_03392 2.8e-97 ydhK M Protein of unknown function (DUF1541)
NMLFEMLE_03393 1.3e-199 pbuE EGP Major facilitator Superfamily
NMLFEMLE_03394 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NMLFEMLE_03395 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NMLFEMLE_03396 1.7e-238 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMLFEMLE_03397 5.8e-282 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMLFEMLE_03398 1.1e-132 ydhQ K UTRA
NMLFEMLE_03399 2.2e-165 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NMLFEMLE_03400 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
NMLFEMLE_03401 2.9e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NMLFEMLE_03402 2.3e-156 ydhU P Catalase
NMLFEMLE_03405 3.4e-39 S COG NOG14552 non supervised orthologous group
NMLFEMLE_03406 7.8e-08
NMLFEMLE_03408 6e-177 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NMLFEMLE_03409 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NMLFEMLE_03410 2.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NMLFEMLE_03411 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NMLFEMLE_03412 3.9e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NMLFEMLE_03413 0.0 ydiF S ABC transporter
NMLFEMLE_03414 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NMLFEMLE_03415 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NMLFEMLE_03416 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NMLFEMLE_03417 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NMLFEMLE_03418 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NMLFEMLE_03419 7.9e-129 ydiL S CAAX protease self-immunity
NMLFEMLE_03420 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NMLFEMLE_03421 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NMLFEMLE_03422 2.8e-144 L Belongs to the 'phage' integrase family
NMLFEMLE_03423 4.7e-48 xkdA E IrrE N-terminal-like domain
NMLFEMLE_03424 1.8e-27 S Protein of unknown function (DUF4064)
NMLFEMLE_03425 1.1e-47
NMLFEMLE_03427 1.1e-16 xre K Helix-turn-helix XRE-family like proteins
NMLFEMLE_03428 8.4e-13 K Helix-turn-helix domain
NMLFEMLE_03429 2e-33
NMLFEMLE_03430 8.4e-73 K BRO family, N-terminal domain
NMLFEMLE_03431 1.6e-89
NMLFEMLE_03435 4.9e-163 yqaJ L YqaJ-like viral recombinase domain
NMLFEMLE_03436 1e-148 recT L RecT family
NMLFEMLE_03437 9.7e-36 3.1.3.16 L DnaD domain protein
NMLFEMLE_03438 1.6e-127 xkdC L IstB-like ATP binding protein
NMLFEMLE_03441 1.4e-54 S Protein of unknown function (DUF1064)
NMLFEMLE_03443 7.1e-27 yqaO S Phage-like element PBSX protein XtrA
NMLFEMLE_03448 4e-08 S YopX protein
NMLFEMLE_03453 4.5e-62
NMLFEMLE_03460 1.9e-80 L Transposase
NMLFEMLE_03461 1.4e-45 L Terminase small subunit
NMLFEMLE_03462 2.6e-196 S Phage terminase large subunit
NMLFEMLE_03464 3.1e-121 S Phage portal protein, SPP1 Gp6-like
NMLFEMLE_03465 2.6e-81 S Phage Mu protein F like protein
NMLFEMLE_03468 5.4e-44 S Phage minor structural protein GP20
NMLFEMLE_03469 1.1e-16 gpG
NMLFEMLE_03470 1.5e-22 gpG
NMLFEMLE_03472 6.4e-29 S Phage gp6-like head-tail connector protein
NMLFEMLE_03473 8.2e-28 S Phage head-tail joining protein
NMLFEMLE_03474 8.9e-37 S Bacteriophage HK97-gp10, putative tail-component
NMLFEMLE_03475 3.8e-29 S Protein of unknown function (DUF3168)
NMLFEMLE_03476 8.7e-34 S Phage tail tube protein
NMLFEMLE_03477 1.8e-09 chiA 3.2.1.14 GH18 G Glycosyl hydrolases family 18
NMLFEMLE_03478 7.1e-28 S Phage tail assembly chaperone protein, TAC
NMLFEMLE_03479 1.2e-140
NMLFEMLE_03480 2e-50
NMLFEMLE_03481 1.1e-222 S peptidoglycan catabolic process
NMLFEMLE_03486 4.4e-22 xhlA S Haemolysin XhlA
NMLFEMLE_03487 5.1e-30 xhlB S SPP1 phage holin
NMLFEMLE_03488 9.8e-104 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NMLFEMLE_03489 9e-41 S protein domain associated with
NMLFEMLE_03491 6.1e-27 K Helix-turn-helix domain
NMLFEMLE_03492 3.4e-67 rnhA 3.1.26.4 L Caulimovirus viroplasmin
NMLFEMLE_03493 4.9e-07 S Antitoxin to bacterial toxin RNase LS or RnlA
NMLFEMLE_03494 4.1e-13
NMLFEMLE_03495 6.8e-152 ydjC S Abhydrolase domain containing 18
NMLFEMLE_03496 0.0 K NB-ARC domain
NMLFEMLE_03497 8.5e-201 gutB 1.1.1.14 E Dehydrogenase
NMLFEMLE_03498 6.7e-254 gutA G MFS/sugar transport protein
NMLFEMLE_03499 7.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NMLFEMLE_03500 5.6e-113 pspA KT Phage shock protein A
NMLFEMLE_03501 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMLFEMLE_03502 4.1e-96 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NMLFEMLE_03503 2.4e-19 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NMLFEMLE_03504 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
NMLFEMLE_03505 4.7e-196 S Ion transport 2 domain protein
NMLFEMLE_03506 2.7e-258 iolT EGP Major facilitator Superfamily
NMLFEMLE_03507 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NMLFEMLE_03508 4.5e-64 ydjM M Lytic transglycolase
NMLFEMLE_03509 1.5e-152 ydjN U Involved in the tonB-independent uptake of proteins
NMLFEMLE_03511 1.4e-34 ydjO S Cold-inducible protein YdjO
NMLFEMLE_03512 9.5e-160 ydjP I Alpha/beta hydrolase family
NMLFEMLE_03513 1.6e-177 yeaA S Protein of unknown function (DUF4003)
NMLFEMLE_03514 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NMLFEMLE_03515 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NMLFEMLE_03516 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMLFEMLE_03517 1.7e-176 yeaC S COG0714 MoxR-like ATPases
NMLFEMLE_03518 3.6e-224 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NMLFEMLE_03519 0.0 yebA E COG1305 Transglutaminase-like enzymes
NMLFEMLE_03520 7.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NMLFEMLE_03521 1e-85 K Belongs to the sigma-70 factor family. ECF subfamily
NMLFEMLE_03522 1.7e-252 S Domain of unknown function (DUF4179)
NMLFEMLE_03523 5.1e-211 pbuG S permease
NMLFEMLE_03524 2.3e-118 yebC M Membrane
NMLFEMLE_03526 8.9e-93 yebE S UPF0316 protein
NMLFEMLE_03527 8e-28 yebG S NETI protein
NMLFEMLE_03528 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NMLFEMLE_03529 1.5e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NMLFEMLE_03530 2.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NMLFEMLE_03531 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NMLFEMLE_03532 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMLFEMLE_03533 1.9e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMLFEMLE_03534 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMLFEMLE_03535 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NMLFEMLE_03536 3.2e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NMLFEMLE_03537 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NMLFEMLE_03538 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NMLFEMLE_03539 2.2e-232 purD 6.3.4.13 F Belongs to the GARS family
NMLFEMLE_03540 1e-72 K helix_turn_helix ASNC type
NMLFEMLE_03541 7.3e-231 yjeH E Amino acid permease
NMLFEMLE_03542 2.7e-27 S Protein of unknown function (DUF2892)
NMLFEMLE_03543 0.0 yerA 3.5.4.2 F adenine deaminase
NMLFEMLE_03544 1.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
NMLFEMLE_03545 4.8e-51 yerC S protein conserved in bacteria
NMLFEMLE_03546 2.6e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NMLFEMLE_03548 1.4e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NMLFEMLE_03549 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NMLFEMLE_03550 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NMLFEMLE_03551 7.3e-209 camS S COG4851 Protein involved in sex pheromone biosynthesis
NMLFEMLE_03552 5e-195 yerI S homoserine kinase type II (protein kinase fold)
NMLFEMLE_03553 1.6e-45 sapB S MgtC SapB transporter
NMLFEMLE_03554 1.2e-54 sapB S MgtC SapB transporter
NMLFEMLE_03555 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMLFEMLE_03556 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMLFEMLE_03557 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NMLFEMLE_03558 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMLFEMLE_03559 1.3e-146 yerO K Transcriptional regulator
NMLFEMLE_03560 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NMLFEMLE_03561 5.1e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NMLFEMLE_03562 4.6e-247 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMLFEMLE_03564 6.9e-100 S response regulator aspartate phosphatase
NMLFEMLE_03566 6.3e-40 S Immunity protein 22
NMLFEMLE_03567 3.3e-187 yobL S Bacterial EndoU nuclease
NMLFEMLE_03568 2e-178 3.4.24.40 CO amine dehydrogenase activity
NMLFEMLE_03569 6.7e-39
NMLFEMLE_03570 7.9e-213 S Tetratricopeptide repeat
NMLFEMLE_03572 2.7e-126 yeeN K transcriptional regulatory protein
NMLFEMLE_03574 3.6e-100 dhaR3 K Transcriptional regulator
NMLFEMLE_03575 8.2e-81 yesE S SnoaL-like domain
NMLFEMLE_03576 1.3e-151 yesF GM NAD(P)H-binding
NMLFEMLE_03577 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NMLFEMLE_03578 1.5e-45 cotJB S CotJB protein
NMLFEMLE_03579 5.2e-104 cotJC P Spore Coat
NMLFEMLE_03580 6e-102 yesJ K Acetyltransferase (GNAT) family
NMLFEMLE_03582 3.1e-102 yesL S Protein of unknown function, DUF624
NMLFEMLE_03583 0.0 yesM 2.7.13.3 T Histidine kinase
NMLFEMLE_03584 1e-201 yesN K helix_turn_helix, arabinose operon control protein
NMLFEMLE_03585 8e-246 yesO G Bacterial extracellular solute-binding protein
NMLFEMLE_03586 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
NMLFEMLE_03587 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
NMLFEMLE_03588 2.3e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NMLFEMLE_03589 0.0 yesS K Transcriptional regulator
NMLFEMLE_03590 4.4e-129 E GDSL-like Lipase/Acylhydrolase
NMLFEMLE_03591 3.3e-57 yesU S Domain of unknown function (DUF1961)
NMLFEMLE_03592 1.3e-111 yesV S Protein of unknown function, DUF624
NMLFEMLE_03593 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NMLFEMLE_03594 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NMLFEMLE_03596 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
NMLFEMLE_03597 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NMLFEMLE_03598 0.0 yetA
NMLFEMLE_03599 2.8e-290 lplA G Bacterial extracellular solute-binding protein
NMLFEMLE_03600 1.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NMLFEMLE_03601 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
NMLFEMLE_03602 4.9e-254 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NMLFEMLE_03603 8.8e-122 yetF S membrane
NMLFEMLE_03604 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NMLFEMLE_03605 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMLFEMLE_03606 2.2e-34
NMLFEMLE_03607 5.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMLFEMLE_03608 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
NMLFEMLE_03609 5.3e-105 yetJ S Belongs to the BI1 family
NMLFEMLE_03610 1.4e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
NMLFEMLE_03611 4e-209 yetM CH FAD binding domain
NMLFEMLE_03612 1.7e-133 M Membrane
NMLFEMLE_03613 3.7e-196 yetN S Protein of unknown function (DUF3900)
NMLFEMLE_03614 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NMLFEMLE_03615 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMLFEMLE_03616 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
NMLFEMLE_03617 1.9e-172 yfnG 4.2.1.45 M dehydratase
NMLFEMLE_03618 1.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
NMLFEMLE_03619 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NMLFEMLE_03620 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
NMLFEMLE_03621 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
NMLFEMLE_03622 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NMLFEMLE_03623 8.4e-241 yfnA E amino acid
NMLFEMLE_03624 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMLFEMLE_03625 1.1e-113 yfmS NT chemotaxis protein
NMLFEMLE_03626 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NMLFEMLE_03627 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
NMLFEMLE_03628 2.8e-70 yfmP K transcriptional
NMLFEMLE_03629 4.3e-209 yfmO EGP Major facilitator Superfamily
NMLFEMLE_03630 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NMLFEMLE_03631 2.9e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NMLFEMLE_03632 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
NMLFEMLE_03633 9.4e-189 yfmJ S N-terminal domain of oxidoreductase
NMLFEMLE_03634 7.7e-214 G Major Facilitator Superfamily
NMLFEMLE_03635 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
NMLFEMLE_03636 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NMLFEMLE_03637 2e-167 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMLFEMLE_03638 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMLFEMLE_03639 1.7e-168 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NMLFEMLE_03640 2.6e-24 S Protein of unknown function (DUF3212)
NMLFEMLE_03641 7.6e-58 yflT S Heat induced stress protein YflT
NMLFEMLE_03642 2.5e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NMLFEMLE_03643 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
NMLFEMLE_03644 1.7e-278 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NMLFEMLE_03645 2.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
NMLFEMLE_03646 8.5e-227 citM C Citrate transporter
NMLFEMLE_03647 3.9e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NMLFEMLE_03648 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NMLFEMLE_03649 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NMLFEMLE_03650 9.9e-123 yflK S protein conserved in bacteria
NMLFEMLE_03651 4e-18 yflJ S Protein of unknown function (DUF2639)
NMLFEMLE_03652 4.1e-19 yflI
NMLFEMLE_03653 5.3e-50 yflH S Protein of unknown function (DUF3243)
NMLFEMLE_03654 4.2e-138 map 3.4.11.18 E Methionine aminopeptidase
NMLFEMLE_03655 1e-45 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NMLFEMLE_03656 2.6e-155 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NMLFEMLE_03657 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMLFEMLE_03658 6e-67 yhdN S Domain of unknown function (DUF1992)
NMLFEMLE_03659 2.8e-252 agcS_1 E Sodium alanine symporter
NMLFEMLE_03660 3e-193 E Spore germination protein
NMLFEMLE_03662 3.3e-206 yfkR S spore germination
NMLFEMLE_03663 4.9e-282 yfkQ EG Spore germination protein
NMLFEMLE_03664 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMLFEMLE_03665 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NMLFEMLE_03666 1.8e-133 treR K transcriptional
NMLFEMLE_03667 1.1e-124 yfkO C nitroreductase
NMLFEMLE_03668 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NMLFEMLE_03669 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
NMLFEMLE_03670 5.8e-206 ydiM EGP Major facilitator Superfamily
NMLFEMLE_03671 3.5e-29 yfkK S Belongs to the UPF0435 family
NMLFEMLE_03672 3.8e-54 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMLFEMLE_03673 7.1e-50 yfkI S gas vesicle protein
NMLFEMLE_03674 1.3e-143 yihY S Belongs to the UPF0761 family
NMLFEMLE_03675 5e-08
NMLFEMLE_03676 3.4e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NMLFEMLE_03677 6.1e-183 cax P COG0387 Ca2 H antiporter
NMLFEMLE_03678 1.2e-146 yfkD S YfkD-like protein
NMLFEMLE_03679 7.8e-149 yfkC M Mechanosensitive ion channel
NMLFEMLE_03680 5.4e-222 yfkA S YfkB-like domain
NMLFEMLE_03681 1.1e-26 yfjT
NMLFEMLE_03682 1.7e-153 pdaA G deacetylase
NMLFEMLE_03683 1.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NMLFEMLE_03684 1.7e-184 corA P Mediates influx of magnesium ions
NMLFEMLE_03685 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NMLFEMLE_03686 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMLFEMLE_03687 6.7e-44 S YfzA-like protein
NMLFEMLE_03688 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMLFEMLE_03689 1.9e-85 yfjM S Psort location Cytoplasmic, score
NMLFEMLE_03690 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NMLFEMLE_03691 2.1e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMLFEMLE_03692 2.4e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMLFEMLE_03693 2.3e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NMLFEMLE_03694 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NMLFEMLE_03695 1.2e-25 sspH S Belongs to the SspH family
NMLFEMLE_03696 1.2e-55 yfjF S UPF0060 membrane protein
NMLFEMLE_03697 1.4e-85 S Family of unknown function (DUF5381)
NMLFEMLE_03698 2.3e-123 yfjC
NMLFEMLE_03699 9.6e-172 yfjB
NMLFEMLE_03700 1.7e-43 yfjA S Belongs to the WXG100 family
NMLFEMLE_03701 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NMLFEMLE_03702 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
NMLFEMLE_03703 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMLFEMLE_03704 2.1e-310 yfiB3 V ABC transporter
NMLFEMLE_03705 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMLFEMLE_03706 9.8e-65 mhqP S DoxX
NMLFEMLE_03707 4e-116 yfiE 1.13.11.2 S glyoxalase
NMLFEMLE_03709 3.4e-211 yxjM T Histidine kinase
NMLFEMLE_03710 5.4e-113 KT LuxR family transcriptional regulator
NMLFEMLE_03711 4.6e-70 V ABC transporter, ATP-binding protein
NMLFEMLE_03712 3e-90 V ABC transporter, ATP-binding protein
NMLFEMLE_03713 1.7e-205 V ABC-2 family transporter protein
NMLFEMLE_03714 3.8e-202 V COG0842 ABC-type multidrug transport system, permease component
NMLFEMLE_03715 8.3e-99 padR K transcriptional
NMLFEMLE_03716 1.7e-79 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NMLFEMLE_03717 2.9e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NMLFEMLE_03718 3.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
NMLFEMLE_03719 3.4e-283 yfiU EGP Major facilitator Superfamily
NMLFEMLE_03720 2.2e-79 yfiV K transcriptional
NMLFEMLE_03721 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NMLFEMLE_03722 3.7e-166 yfiY P ABC transporter substrate-binding protein
NMLFEMLE_03723 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMLFEMLE_03724 2.9e-169 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMLFEMLE_03725 1.6e-165 yfhB 5.3.3.17 S PhzF family
NMLFEMLE_03726 3.9e-107 yfhC C nitroreductase
NMLFEMLE_03727 2.1e-25 yfhD S YfhD-like protein
NMLFEMLE_03729 6e-171 yfhF S nucleoside-diphosphate sugar epimerase
NMLFEMLE_03730 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NMLFEMLE_03731 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NMLFEMLE_03732 1.2e-99 yfhI EGP Major facilitator Superfamily
NMLFEMLE_03733 4.3e-101 yfhI EGP Major facilitator Superfamily
NMLFEMLE_03734 9e-19 sspK S reproduction
NMLFEMLE_03735 1.3e-44 yfhJ S WVELL protein
NMLFEMLE_03736 2.1e-88 batE T Bacterial SH3 domain homologues
NMLFEMLE_03737 3.5e-51 yfhL S SdpI/YhfL protein family
NMLFEMLE_03738 3.1e-169 yfhM S Alpha beta hydrolase
NMLFEMLE_03739 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NMLFEMLE_03740 0.0 yfhO S Bacterial membrane protein YfhO
NMLFEMLE_03741 5.5e-186 yfhP S membrane-bound metal-dependent
NMLFEMLE_03742 7.8e-212 mutY L A G-specific
NMLFEMLE_03743 2.6e-35 yfhS
NMLFEMLE_03744 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMLFEMLE_03745 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NMLFEMLE_03746 1.5e-37 ygaB S YgaB-like protein
NMLFEMLE_03747 1.3e-104 ygaC J Belongs to the UPF0374 family
NMLFEMLE_03748 1.8e-301 ygaD V ABC transporter
NMLFEMLE_03749 8.7e-180 ygaE S Membrane
NMLFEMLE_03750 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NMLFEMLE_03751 6.3e-87 bcp 1.11.1.15 O Peroxiredoxin
NMLFEMLE_03752 4e-80 perR P Belongs to the Fur family
NMLFEMLE_03753 2.8e-55 ygzB S UPF0295 protein
NMLFEMLE_03754 1.5e-166 ygxA S Nucleotidyltransferase-like
NMLFEMLE_03755 3.4e-39 S COG NOG14552 non supervised orthologous group
NMLFEMLE_03760 7.8e-08
NMLFEMLE_03768 2e-08
NMLFEMLE_03772 2.7e-143 spo0M S COG4326 Sporulation control protein
NMLFEMLE_03773 3e-27
NMLFEMLE_03774 1.3e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NMLFEMLE_03776 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NMLFEMLE_03777 2.2e-262 ygaK C Berberine and berberine like
NMLFEMLE_03779 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NMLFEMLE_03780 3.7e-137 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NMLFEMLE_03781 1.8e-168 ssuA M Sulfonate ABC transporter
NMLFEMLE_03782 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NMLFEMLE_03783 2e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NMLFEMLE_03785 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMLFEMLE_03786 4.1e-78 ygaO
NMLFEMLE_03787 4.4e-29 K Transcriptional regulator
NMLFEMLE_03789 3.9e-113 yhzB S B3/4 domain
NMLFEMLE_03790 1.7e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NMLFEMLE_03791 1.8e-175 yhbB S Putative amidase domain
NMLFEMLE_03792 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NMLFEMLE_03793 1.3e-108 yhbD K Protein of unknown function (DUF4004)
NMLFEMLE_03794 5.9e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NMLFEMLE_03795 2.1e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NMLFEMLE_03796 0.0 prkA T Ser protein kinase
NMLFEMLE_03797 2.5e-225 yhbH S Belongs to the UPF0229 family
NMLFEMLE_03798 2.2e-76 yhbI K DNA-binding transcription factor activity
NMLFEMLE_03799 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NMLFEMLE_03800 4.1e-69 yhcA EGP Major facilitator Superfamily
NMLFEMLE_03801 5.6e-193 yhcA EGP Major facilitator Superfamily
NMLFEMLE_03802 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NMLFEMLE_03803 2.8e-37 yhcC
NMLFEMLE_03804 7.8e-55
NMLFEMLE_03805 6.6e-60 yhcF K Transcriptional regulator
NMLFEMLE_03806 1.6e-123 yhcG V ABC transporter, ATP-binding protein
NMLFEMLE_03807 1e-165 yhcH V ABC transporter, ATP-binding protein
NMLFEMLE_03808 8.7e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NMLFEMLE_03809 1e-30 cspB K Cold-shock protein
NMLFEMLE_03810 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
NMLFEMLE_03811 3.4e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NMLFEMLE_03812 6.3e-184 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMLFEMLE_03813 1.1e-40 yhcM
NMLFEMLE_03814 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMLFEMLE_03815 1.2e-147 yhcP
NMLFEMLE_03816 1.5e-99 yhcQ M Spore coat protein
NMLFEMLE_03817 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NMLFEMLE_03818 8.7e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NMLFEMLE_03819 4.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMLFEMLE_03820 9.3e-68 yhcU S Family of unknown function (DUF5365)
NMLFEMLE_03821 9.9e-68 yhcV S COG0517 FOG CBS domain
NMLFEMLE_03822 1.3e-119 yhcW 5.4.2.6 S hydrolase
NMLFEMLE_03823 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NMLFEMLE_03824 1.6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMLFEMLE_03825 5.2e-81 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NMLFEMLE_03826 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NMLFEMLE_03827 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NMLFEMLE_03828 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NMLFEMLE_03829 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NMLFEMLE_03830 8.8e-212 yhcY 2.7.13.3 T Histidine kinase
NMLFEMLE_03831 1.9e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMLFEMLE_03832 3.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
NMLFEMLE_03833 1.2e-38 yhdB S YhdB-like protein
NMLFEMLE_03834 4.8e-54 yhdC S Protein of unknown function (DUF3889)
NMLFEMLE_03835 4.3e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NMLFEMLE_03836 1e-75 nsrR K Transcriptional regulator
NMLFEMLE_03837 1.5e-238 ygxB M Conserved TM helix
NMLFEMLE_03838 2.1e-276 ycgB S Stage V sporulation protein R
NMLFEMLE_03839 1.3e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NMLFEMLE_03840 5.3e-128 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NMLFEMLE_03841 3.8e-162 citR K Transcriptional regulator
NMLFEMLE_03842 2.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
NMLFEMLE_03843 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMLFEMLE_03844 3.4e-250 yhdG E amino acid
NMLFEMLE_03845 2.8e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NMLFEMLE_03846 7.4e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMLFEMLE_03847 2e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMLFEMLE_03848 8.1e-45 yhdK S Sigma-M inhibitor protein
NMLFEMLE_03849 2.5e-200 yhdL S Sigma factor regulator N-terminal
NMLFEMLE_03850 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NMLFEMLE_03851 1.1e-161 yhdN C Aldo keto reductase
NMLFEMLE_03852 5.4e-22 yhdN C Aldo keto reductase
NMLFEMLE_03853 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NMLFEMLE_03854 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NMLFEMLE_03855 4.2e-74 cueR K transcriptional
NMLFEMLE_03856 2.6e-222 yhdR 2.6.1.1 E Aminotransferase
NMLFEMLE_03857 7.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NMLFEMLE_03858 1.4e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMLFEMLE_03859 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMLFEMLE_03860 1.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NMLFEMLE_03862 5.6e-203 yhdY M Mechanosensitive ion channel
NMLFEMLE_03863 2.6e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NMLFEMLE_03864 1.9e-150 yheN G deacetylase
NMLFEMLE_03865 3.4e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NMLFEMLE_03866 3.5e-231 nhaC C Na H antiporter
NMLFEMLE_03867 5.2e-84 nhaX T Belongs to the universal stress protein A family
NMLFEMLE_03868 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMLFEMLE_03869 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMLFEMLE_03870 2.4e-110 yheG GM NAD(P)H-binding
NMLFEMLE_03871 6.3e-28 sspB S spore protein
NMLFEMLE_03872 1.3e-36 yheE S Family of unknown function (DUF5342)
NMLFEMLE_03873 1e-267 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NMLFEMLE_03874 7.4e-216 yheC HJ YheC/D like ATP-grasp
NMLFEMLE_03875 1.4e-201 yheB S Belongs to the UPF0754 family
NMLFEMLE_03876 9.5e-48 yheA S Belongs to the UPF0342 family
NMLFEMLE_03877 1.5e-205 yhaZ L DNA alkylation repair enzyme
NMLFEMLE_03878 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NMLFEMLE_03879 1.8e-292 hemZ H coproporphyrinogen III oxidase
NMLFEMLE_03880 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NMLFEMLE_03881 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NMLFEMLE_03883 6.7e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
NMLFEMLE_03884 2.4e-26 S YhzD-like protein
NMLFEMLE_03885 5.2e-167 yhaQ S ABC transporter, ATP-binding protein
NMLFEMLE_03886 6.1e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NMLFEMLE_03887 9.7e-225 yhaO L DNA repair exonuclease
NMLFEMLE_03888 0.0 yhaN L AAA domain
NMLFEMLE_03889 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NMLFEMLE_03890 1.6e-21 yhaL S Sporulation protein YhaL
NMLFEMLE_03891 3.2e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NMLFEMLE_03892 7.3e-89 yhaK S Putative zincin peptidase
NMLFEMLE_03893 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NMLFEMLE_03894 1e-113 hpr K Negative regulator of protease production and sporulation
NMLFEMLE_03895 7e-39 yhaH S YtxH-like protein
NMLFEMLE_03896 5.4e-21
NMLFEMLE_03897 3.1e-79 trpP S Tryptophan transporter TrpP
NMLFEMLE_03898 5.4e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NMLFEMLE_03899 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NMLFEMLE_03900 4.6e-137 ecsA V transporter (ATP-binding protein)
NMLFEMLE_03901 2e-214 ecsB U ABC transporter
NMLFEMLE_03902 4.6e-110 ecsC S EcsC protein family
NMLFEMLE_03903 3.1e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NMLFEMLE_03904 1.1e-245 yhfA C membrane
NMLFEMLE_03905 1e-32 1.15.1.2 C Rubrerythrin
NMLFEMLE_03906 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NMLFEMLE_03907 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NMLFEMLE_03908 4.1e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NMLFEMLE_03909 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NMLFEMLE_03910 4.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NMLFEMLE_03911 5.4e-101 yhgD K Transcriptional regulator
NMLFEMLE_03912 3e-214 yhgE S YhgE Pip N-terminal domain protein
NMLFEMLE_03913 1.1e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMLFEMLE_03914 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
NMLFEMLE_03915 3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NMLFEMLE_03916 3.7e-72 3.4.13.21 S ASCH
NMLFEMLE_03917 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMLFEMLE_03918 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NMLFEMLE_03919 4.9e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
NMLFEMLE_03920 5e-111 yhfK GM NmrA-like family
NMLFEMLE_03921 5.4e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NMLFEMLE_03922 1.9e-65 yhfM
NMLFEMLE_03923 5.9e-241 yhfN 3.4.24.84 O Peptidase M48
NMLFEMLE_03924 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NMLFEMLE_03925 8.1e-76 VY92_01935 K acetyltransferase
NMLFEMLE_03926 7e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
NMLFEMLE_03927 4.3e-159 yfmC M Periplasmic binding protein
NMLFEMLE_03928 2.1e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NMLFEMLE_03929 1.1e-195 vraB 2.3.1.9 I Belongs to the thiolase family
NMLFEMLE_03930 1.2e-271 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NMLFEMLE_03931 5e-91 bioY S BioY family
NMLFEMLE_03932 6.3e-182 hemAT NT chemotaxis protein
NMLFEMLE_03933 2.3e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NMLFEMLE_03934 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMLFEMLE_03935 1.3e-32 yhzC S IDEAL
NMLFEMLE_03936 4e-107 comK K Competence transcription factor
NMLFEMLE_03937 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
NMLFEMLE_03938 7.8e-42 yhjA S Excalibur calcium-binding domain
NMLFEMLE_03939 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMLFEMLE_03940 6.9e-27 yhjC S Protein of unknown function (DUF3311)
NMLFEMLE_03941 5e-60 yhjD
NMLFEMLE_03942 2.8e-76 yhjE S SNARE associated Golgi protein
NMLFEMLE_03943 1.2e-22 yhjE S SNARE associated Golgi protein
NMLFEMLE_03944 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NMLFEMLE_03945 1.2e-280 yhjG CH FAD binding domain
NMLFEMLE_03946 3.4e-90 yhjH K helix_turn_helix multiple antibiotic resistance protein
NMLFEMLE_03947 3.8e-213 glcP G Major Facilitator Superfamily
NMLFEMLE_03948 6e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NMLFEMLE_03949 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NMLFEMLE_03950 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NMLFEMLE_03951 1.7e-187 yhjM 5.1.1.1 K Transcriptional regulator
NMLFEMLE_03952 1.9e-201 abrB S membrane
NMLFEMLE_03953 9e-215 EGP Transmembrane secretion effector
NMLFEMLE_03954 0.0 S Sugar transport-related sRNA regulator N-term
NMLFEMLE_03955 2e-36 yhjQ C COG1145 Ferredoxin
NMLFEMLE_03956 2.2e-78 yhjR S Rubrerythrin
NMLFEMLE_03957 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NMLFEMLE_03958 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NMLFEMLE_03959 9.2e-158 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NMLFEMLE_03960 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NMLFEMLE_03961 0.0 sbcC L COG0419 ATPase involved in DNA repair
NMLFEMLE_03962 3e-50 yisB V COG1403 Restriction endonuclease
NMLFEMLE_03963 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NMLFEMLE_03964 3e-66 gerPE S Spore germination protein GerPE
NMLFEMLE_03965 6.3e-24 gerPD S Spore germination protein
NMLFEMLE_03966 1.8e-54 gerPC S Spore germination protein
NMLFEMLE_03967 4e-34 gerPB S cell differentiation
NMLFEMLE_03968 1.9e-33 gerPA S Spore germination protein
NMLFEMLE_03969 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NMLFEMLE_03970 2.5e-172 cotH M Spore Coat
NMLFEMLE_03971 5.4e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NMLFEMLE_03972 6.6e-57 yisL S UPF0344 protein
NMLFEMLE_03973 0.0 wprA O Belongs to the peptidase S8 family
NMLFEMLE_03974 1.3e-102 yisN S Protein of unknown function (DUF2777)
NMLFEMLE_03975 0.0 asnO 6.3.5.4 E Asparagine synthase
NMLFEMLE_03976 6.4e-88 yizA S Damage-inducible protein DinB
NMLFEMLE_03977 1.7e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NMLFEMLE_03978 1.5e-242 yisQ V Mate efflux family protein
NMLFEMLE_03979 3.5e-160 yisR K Transcriptional regulator
NMLFEMLE_03980 6.9e-184 purR K helix_turn _helix lactose operon repressor
NMLFEMLE_03981 3.7e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NMLFEMLE_03982 5.3e-92 yisT S DinB family
NMLFEMLE_03983 2.7e-106 argO S Lysine exporter protein LysE YggA
NMLFEMLE_03984 3.1e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMLFEMLE_03985 6.8e-36 mcbG S Pentapeptide repeats (9 copies)
NMLFEMLE_03986 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMLFEMLE_03987 1.4e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NMLFEMLE_03988 7.4e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NMLFEMLE_03989 2.1e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NMLFEMLE_03990 1.9e-121 comB 3.1.3.71 H Belongs to the ComB family
NMLFEMLE_03991 1.9e-141 yitD 4.4.1.19 S synthase
NMLFEMLE_03992 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMLFEMLE_03993 4.6e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NMLFEMLE_03994 1.5e-228 yitG EGP Major facilitator Superfamily
NMLFEMLE_03995 5.1e-156 yitH K Acetyltransferase (GNAT) domain
NMLFEMLE_03996 1.3e-81 yjcF S Acetyltransferase (GNAT) domain
NMLFEMLE_03997 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NMLFEMLE_03998 3.3e-54 yajQ S Belongs to the UPF0234 family
NMLFEMLE_03999 4e-161 cvfB S protein conserved in bacteria
NMLFEMLE_04000 8.5e-94
NMLFEMLE_04001 3.6e-171
NMLFEMLE_04002 1.5e-97 S Sporulation delaying protein SdpA
NMLFEMLE_04003 1.5e-58 K Transcriptional regulator PadR-like family
NMLFEMLE_04004 5e-94
NMLFEMLE_04005 1.4e-44 yitR S Domain of unknown function (DUF3784)
NMLFEMLE_04006 1.1e-308 nprB 3.4.24.28 E Peptidase M4
NMLFEMLE_04007 2.7e-157 yitS S protein conserved in bacteria
NMLFEMLE_04008 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NMLFEMLE_04009 1.7e-73 ipi S Intracellular proteinase inhibitor
NMLFEMLE_04010 1.2e-17 S Protein of unknown function (DUF3813)
NMLFEMLE_04012 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NMLFEMLE_04013 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NMLFEMLE_04014 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NMLFEMLE_04015 1.5e-22 pilT S Proteolipid membrane potential modulator
NMLFEMLE_04016 4.7e-271 yitY C D-arabinono-1,4-lactone oxidase
NMLFEMLE_04017 1.7e-88 norB G Major Facilitator Superfamily
NMLFEMLE_04018 3.5e-199 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NMLFEMLE_04019 5.9e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NMLFEMLE_04020 3.4e-15 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NMLFEMLE_04021 1.5e-107 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NMLFEMLE_04022 2.7e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NMLFEMLE_04023 9.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NMLFEMLE_04024 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NMLFEMLE_04025 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NMLFEMLE_04026 9.5e-28 yjzC S YjzC-like protein
NMLFEMLE_04027 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NMLFEMLE_04028 6.2e-142 yjaU I carboxylic ester hydrolase activity
NMLFEMLE_04029 1.8e-101 yjaV
NMLFEMLE_04030 2.5e-183 med S Transcriptional activator protein med
NMLFEMLE_04031 7.3e-26 comZ S ComZ
NMLFEMLE_04032 2.7e-22 yjzB
NMLFEMLE_04033 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMLFEMLE_04034 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NMLFEMLE_04035 7.8e-151 yjaZ O Zn-dependent protease
NMLFEMLE_04036 1.8e-184 appD P Belongs to the ABC transporter superfamily
NMLFEMLE_04037 6.5e-187 appF E Belongs to the ABC transporter superfamily
NMLFEMLE_04038 1.4e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NMLFEMLE_04039 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMLFEMLE_04040 5.4e-26 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMLFEMLE_04041 4.8e-117 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMLFEMLE_04042 5e-147 yjbA S Belongs to the UPF0736 family
NMLFEMLE_04043 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NMLFEMLE_04044 0.0 oppA E ABC transporter substrate-binding protein
NMLFEMLE_04045 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMLFEMLE_04046 1e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMLFEMLE_04047 3.4e-197 oppD P Belongs to the ABC transporter superfamily
NMLFEMLE_04048 5.5e-172 oppF E Belongs to the ABC transporter superfamily
NMLFEMLE_04049 5.4e-210 yjbB EGP Major Facilitator Superfamily
NMLFEMLE_04050 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMLFEMLE_04051 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NMLFEMLE_04052 6e-112 yjbE P Integral membrane protein TerC family
NMLFEMLE_04053 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NMLFEMLE_04054 2.3e-223 yjbF S Competence protein
NMLFEMLE_04055 0.0 pepF E oligoendopeptidase F
NMLFEMLE_04056 1.8e-20
NMLFEMLE_04058 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NMLFEMLE_04059 3.7e-72 yjbI S Bacterial-like globin
NMLFEMLE_04060 2.2e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NMLFEMLE_04061 1.2e-100 yjbK S protein conserved in bacteria
NMLFEMLE_04062 6e-61 yjbL S Belongs to the UPF0738 family
NMLFEMLE_04063 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NMLFEMLE_04064 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMLFEMLE_04065 9.9e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMLFEMLE_04066 7.3e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NMLFEMLE_04067 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NMLFEMLE_04068 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NMLFEMLE_04069 3.3e-80 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NMLFEMLE_04070 2.6e-18 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NMLFEMLE_04071 3.6e-218 thiO 1.4.3.19 E Glycine oxidase
NMLFEMLE_04072 3e-30 thiS H thiamine diphosphate biosynthetic process
NMLFEMLE_04073 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NMLFEMLE_04074 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NMLFEMLE_04075 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NMLFEMLE_04076 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NMLFEMLE_04077 3e-50 yjbX S Spore coat protein
NMLFEMLE_04078 5.2e-83 cotZ S Spore coat protein
NMLFEMLE_04079 3.4e-96 cotY S Spore coat protein Z
NMLFEMLE_04080 6.4e-77 cotX S Spore Coat Protein X and V domain
NMLFEMLE_04081 5.9e-10 cotW
NMLFEMLE_04082 4e-11 cotW
NMLFEMLE_04083 4.2e-49 cotV S Spore Coat Protein X and V domain
NMLFEMLE_04084 4.3e-56 yjcA S Protein of unknown function (DUF1360)
NMLFEMLE_04087 2.9e-38 spoVIF S Stage VI sporulation protein F
NMLFEMLE_04088 0.0 yjcD 3.6.4.12 L DNA helicase
NMLFEMLE_04089 1.7e-38
NMLFEMLE_04090 3.3e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMLFEMLE_04091 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NMLFEMLE_04092 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
NMLFEMLE_04093 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NMLFEMLE_04094 9.4e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NMLFEMLE_04095 2.9e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
NMLFEMLE_04096 1.1e-212 yjcL S Protein of unknown function (DUF819)
NMLFEMLE_04098 1.7e-48
NMLFEMLE_04099 6.3e-220 yobL S Bacterial EndoU nuclease
NMLFEMLE_04101 3.7e-30 KLT Protein tyrosine kinase
NMLFEMLE_04102 6.5e-17 S YolD-like protein
NMLFEMLE_04103 1.9e-36
NMLFEMLE_04104 9e-19
NMLFEMLE_04106 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
NMLFEMLE_04107 2e-140 IQ Enoyl-(Acyl carrier protein) reductase
NMLFEMLE_04109 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NMLFEMLE_04110 1.6e-110 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NMLFEMLE_04111 9e-42 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NMLFEMLE_04112 1.5e-144 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NMLFEMLE_04113 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
NMLFEMLE_04114 1.9e-47 yjdF S Protein of unknown function (DUF2992)
NMLFEMLE_04115 1e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NMLFEMLE_04117 1.4e-78 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NMLFEMLE_04118 4.2e-29 S Domain of unknown function (DUF4177)
NMLFEMLE_04119 1e-48 yjdJ S Domain of unknown function (DUF4306)
NMLFEMLE_04120 7.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NMLFEMLE_04122 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
NMLFEMLE_04123 3e-81 S Protein of unknown function (DUF2690)
NMLFEMLE_04124 2.3e-20 yjfB S Putative motility protein
NMLFEMLE_04125 3.4e-166 yjfC O Predicted Zn-dependent protease (DUF2268)
NMLFEMLE_04126 1.2e-45 T PhoQ Sensor
NMLFEMLE_04127 1.3e-102 yjgB S Domain of unknown function (DUF4309)
NMLFEMLE_04128 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NMLFEMLE_04129 1.6e-94 yjgD S Protein of unknown function (DUF1641)
NMLFEMLE_04132 2.3e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NMLFEMLE_04134 2.2e-221 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NMLFEMLE_04135 1.6e-216 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NMLFEMLE_04136 8.2e-30
NMLFEMLE_04137 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NMLFEMLE_04138 1.9e-122 ybbM S transport system, permease component
NMLFEMLE_04139 5.4e-133 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NMLFEMLE_04140 1.9e-175 yjlA EG Putative multidrug resistance efflux transporter
NMLFEMLE_04141 4.9e-90 yjlB S Cupin domain
NMLFEMLE_04142 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NMLFEMLE_04143 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
NMLFEMLE_04144 1e-278 uxaC 5.3.1.12 G glucuronate isomerase
NMLFEMLE_04145 9.2e-248 yjmB G symporter YjmB
NMLFEMLE_04146 5.3e-78 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NMLFEMLE_04147 1.2e-85 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NMLFEMLE_04148 8.2e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NMLFEMLE_04149 1.4e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NMLFEMLE_04150 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMLFEMLE_04151 2.8e-144 exuT G Sugar (and other) transporter
NMLFEMLE_04152 1.2e-62 exuT G Sugar (and other) transporter
NMLFEMLE_04153 2.3e-184 exuR K transcriptional
NMLFEMLE_04154 8.4e-262 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NMLFEMLE_04155 3.5e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NMLFEMLE_04156 7.4e-130 MA20_18170 S membrane transporter protein
NMLFEMLE_04157 8e-79 yjoA S DinB family
NMLFEMLE_04158 4e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NMLFEMLE_04159 1e-212 S response regulator aspartate phosphatase
NMLFEMLE_04161 6.3e-41 S YCII-related domain
NMLFEMLE_04162 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NMLFEMLE_04163 6.8e-60 yjqA S Bacterial PH domain
NMLFEMLE_04164 2.1e-111 yjqB S Pfam:DUF867
NMLFEMLE_04165 4.4e-160 ydbD P Catalase
NMLFEMLE_04166 1e-110 xkdA E IrrE N-terminal-like domain
NMLFEMLE_04167 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
NMLFEMLE_04169 2.3e-156 xkdB K sequence-specific DNA binding
NMLFEMLE_04170 9.2e-118 xkdC L Bacterial dnaA protein
NMLFEMLE_04173 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
NMLFEMLE_04174 2.2e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NMLFEMLE_04175 1.3e-137 xtmA L phage terminase small subunit
NMLFEMLE_04176 1.2e-252 xtmB S phage terminase, large subunit
NMLFEMLE_04177 4.6e-285 yqbA S portal protein
NMLFEMLE_04178 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NMLFEMLE_04179 5.8e-169 xkdG S Phage capsid family
NMLFEMLE_04180 1.5e-62 yqbG S Protein of unknown function (DUF3199)
NMLFEMLE_04181 3.3e-64 yqbH S Domain of unknown function (DUF3599)
NMLFEMLE_04182 8.4e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
NMLFEMLE_04183 1.9e-77 xkdJ
NMLFEMLE_04184 2.5e-256 xkdK S Phage tail sheath C-terminal domain
NMLFEMLE_04185 6.1e-76 xkdM S Phage tail tube protein
NMLFEMLE_04186 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
NMLFEMLE_04187 3.4e-263 xkdO L Transglycosylase SLT domain
NMLFEMLE_04188 3.7e-122 xkdP S Lysin motif
NMLFEMLE_04189 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
NMLFEMLE_04190 6.1e-39 xkdR S Protein of unknown function (DUF2577)
NMLFEMLE_04191 2.4e-69 xkdS S Protein of unknown function (DUF2634)
NMLFEMLE_04192 1.1e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NMLFEMLE_04193 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NMLFEMLE_04194 8.7e-41
NMLFEMLE_04195 1.9e-155
NMLFEMLE_04196 7.6e-115
NMLFEMLE_04197 2.6e-55 xkdW S XkdW protein
NMLFEMLE_04198 3.8e-23 xkdX
NMLFEMLE_04199 4.4e-152 xepA
NMLFEMLE_04200 2.8e-39 xhlA S Haemolysin XhlA
NMLFEMLE_04201 9.3e-40 xhlB S SPP1 phage holin
NMLFEMLE_04202 1.2e-160 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMLFEMLE_04204 1.5e-22 spoIISB S Stage II sporulation protein SB
NMLFEMLE_04205 4e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NMLFEMLE_04206 7.6e-175 pit P phosphate transporter
NMLFEMLE_04207 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NMLFEMLE_04208 1.2e-239 steT E amino acid
NMLFEMLE_04209 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NMLFEMLE_04210 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NMLFEMLE_04211 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NMLFEMLE_04213 8.4e-209 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMLFEMLE_04214 4.5e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NMLFEMLE_04215 5.1e-153 dppA E D-aminopeptidase
NMLFEMLE_04216 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMLFEMLE_04217 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMLFEMLE_04218 6.6e-187 dppD P Belongs to the ABC transporter superfamily
NMLFEMLE_04219 0.0 dppE E ABC transporter substrate-binding protein
NMLFEMLE_04221 3.3e-129 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NMLFEMLE_04222 5.2e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NMLFEMLE_04223 8e-123 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NMLFEMLE_04224 2.4e-29 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NMLFEMLE_04225 2.2e-187 ykfD E Belongs to the ABC transporter superfamily
NMLFEMLE_04226 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
NMLFEMLE_04227 2e-160 ykgA E Amidinotransferase
NMLFEMLE_04228 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NMLFEMLE_04229 9.9e-222 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NMLFEMLE_04230 2.7e-129 ykjA S Protein of unknown function (DUF421)
NMLFEMLE_04231 3.9e-98 ykkA S Protein of unknown function (DUF664)
NMLFEMLE_04232 1.1e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMLFEMLE_04233 3.5e-55 ykkC P Multidrug resistance protein
NMLFEMLE_04234 7e-50 ykkD P Multidrug resistance protein
NMLFEMLE_04235 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NMLFEMLE_04236 3.3e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMLFEMLE_04237 6.9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NMLFEMLE_04238 1.3e-70 ohrA O Organic hydroperoxide resistance protein
NMLFEMLE_04239 4.4e-74 ohrR K COG1846 Transcriptional regulators
NMLFEMLE_04240 1.4e-71 ohrB O Organic hydroperoxide resistance protein
NMLFEMLE_04241 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NMLFEMLE_04242 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NMLFEMLE_04243 1.5e-175 isp O Belongs to the peptidase S8 family
NMLFEMLE_04244 2.4e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMLFEMLE_04245 8.4e-134 ykoC P Cobalt transport protein
NMLFEMLE_04246 1e-306 P ABC transporter, ATP-binding protein
NMLFEMLE_04247 2.6e-98 ykoE S ABC-type cobalt transport system, permease component
NMLFEMLE_04248 6.9e-107 ykoF S YKOF-related Family
NMLFEMLE_04249 3.9e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMLFEMLE_04250 1.1e-240 ykoH 2.7.13.3 T Histidine kinase
NMLFEMLE_04251 2.1e-112 ykoI S Peptidase propeptide and YPEB domain
NMLFEMLE_04252 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
NMLFEMLE_04255 2.2e-222 mgtE P Acts as a magnesium transporter
NMLFEMLE_04256 1.1e-19 tnrA K transcriptional
NMLFEMLE_04257 6.7e-18 tnrA K transcriptional
NMLFEMLE_04258 5.9e-18
NMLFEMLE_04259 6.9e-26 ykoL
NMLFEMLE_04260 1.3e-81 mhqR K transcriptional
NMLFEMLE_04261 8.9e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NMLFEMLE_04262 3.7e-99 ykoP G polysaccharide deacetylase
NMLFEMLE_04263 2.1e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NMLFEMLE_04264 0.0 ykoS
NMLFEMLE_04265 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NMLFEMLE_04266 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NMLFEMLE_04267 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NMLFEMLE_04268 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
NMLFEMLE_04269 2.7e-109 ykoX S membrane-associated protein
NMLFEMLE_04270 6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NMLFEMLE_04271 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMLFEMLE_04272 4.8e-117 rsgI S Anti-sigma factor N-terminus
NMLFEMLE_04273 1.9e-26 sspD S small acid-soluble spore protein
NMLFEMLE_04274 1.9e-124 ykrK S Domain of unknown function (DUF1836)
NMLFEMLE_04275 1.3e-154 htpX O Belongs to the peptidase M48B family
NMLFEMLE_04276 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
NMLFEMLE_04277 1.2e-10 ydfR S Protein of unknown function (DUF421)
NMLFEMLE_04278 6.9e-21 ykzE
NMLFEMLE_04279 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NMLFEMLE_04280 0.0 kinE 2.7.13.3 T Histidine kinase
NMLFEMLE_04281 2.7e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NMLFEMLE_04283 3.1e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NMLFEMLE_04284 7e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NMLFEMLE_04285 1.7e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NMLFEMLE_04286 2.6e-230 mtnE 2.6.1.83 E Aminotransferase
NMLFEMLE_04287 2.2e-207 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NMLFEMLE_04288 5e-113 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NMLFEMLE_04289 3.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NMLFEMLE_04290 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NMLFEMLE_04291 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
NMLFEMLE_04292 6.4e-09 S Spo0E like sporulation regulatory protein
NMLFEMLE_04293 5.2e-64 eag
NMLFEMLE_04294 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NMLFEMLE_04295 1.3e-75 ykvE K transcriptional
NMLFEMLE_04296 2.5e-125 motB N Flagellar motor protein
NMLFEMLE_04297 1e-137 motA N flagellar motor
NMLFEMLE_04298 0.0 clpE O Belongs to the ClpA ClpB family
NMLFEMLE_04299 2.6e-178 ykvI S membrane
NMLFEMLE_04300 9.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NMLFEMLE_04301 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NMLFEMLE_04302 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NMLFEMLE_04303 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NMLFEMLE_04304 3.8e-60 ykvN K HxlR-like helix-turn-helix
NMLFEMLE_04305 5.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
NMLFEMLE_04306 8.1e-93 ykvP 3.5.1.28 M Glycosyl transferases group 1
NMLFEMLE_04307 1.5e-74 ykvP 3.5.1.28 M Glycosyl transferases group 1
NMLFEMLE_04308 6.2e-32 3.5.1.104 M LysM domain
NMLFEMLE_04309 6.4e-160 G Glycosyl hydrolases family 18
NMLFEMLE_04310 5.6e-46 ykvR S Protein of unknown function (DUF3219)
NMLFEMLE_04311 6e-25 ykvS S protein conserved in bacteria
NMLFEMLE_04312 2.8e-28
NMLFEMLE_04313 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
NMLFEMLE_04314 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMLFEMLE_04315 1.6e-88 stoA CO thiol-disulfide
NMLFEMLE_04316 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NMLFEMLE_04317 1e-09
NMLFEMLE_04318 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NMLFEMLE_04319 8.3e-179 ykvZ 5.1.1.1 K Transcriptional regulator
NMLFEMLE_04321 7.6e-128 glcT K antiterminator
NMLFEMLE_04322 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMLFEMLE_04323 2.1e-39 ptsH G phosphocarrier protein HPr
NMLFEMLE_04324 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NMLFEMLE_04325 7.2e-39 splA S Transcriptional regulator
NMLFEMLE_04326 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
NMLFEMLE_04327 1.1e-129 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMLFEMLE_04328 1.1e-246 mcpC NT chemotaxis protein
NMLFEMLE_04329 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NMLFEMLE_04330 5.7e-122 ykwD J protein with SCP PR1 domains
NMLFEMLE_04331 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NMLFEMLE_04332 0.0 pilS 2.7.13.3 T Histidine kinase
NMLFEMLE_04333 6.3e-221 patA 2.6.1.1 E Aminotransferase
NMLFEMLE_04334 2.2e-15
NMLFEMLE_04335 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NMLFEMLE_04336 1.7e-84 ykyB S YkyB-like protein
NMLFEMLE_04337 1.6e-238 ykuC EGP Major facilitator Superfamily
NMLFEMLE_04338 1.8e-87 ykuD S protein conserved in bacteria
NMLFEMLE_04339 9.4e-166 ykuE S Metallophosphoesterase
NMLFEMLE_04340 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMLFEMLE_04341 5.2e-234 ykuI T Diguanylate phosphodiesterase
NMLFEMLE_04342 3.9e-37 ykuJ S protein conserved in bacteria
NMLFEMLE_04343 1.2e-65 ykuK S Ribonuclease H-like
NMLFEMLE_04344 3.9e-27 ykzF S Antirepressor AbbA
NMLFEMLE_04345 1.6e-76 ykuL S CBS domain
NMLFEMLE_04346 3.5e-168 ccpC K Transcriptional regulator
NMLFEMLE_04347 3.7e-87 fld C Flavodoxin domain
NMLFEMLE_04348 3.2e-177 ykuO
NMLFEMLE_04349 4.2e-80 fld C Flavodoxin
NMLFEMLE_04350 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NMLFEMLE_04351 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NMLFEMLE_04352 9e-37 ykuS S Belongs to the UPF0180 family
NMLFEMLE_04353 8.8e-142 ykuT M Mechanosensitive ion channel
NMLFEMLE_04354 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NMLFEMLE_04355 6.3e-81 ykuV CO thiol-disulfide
NMLFEMLE_04356 1.5e-93 rok K Repressor of ComK
NMLFEMLE_04357 4.9e-147 yknT
NMLFEMLE_04358 4.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NMLFEMLE_04359 1.1e-83 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NMLFEMLE_04360 2e-58 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NMLFEMLE_04361 2.6e-244 moeA 2.10.1.1 H molybdopterin
NMLFEMLE_04362 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NMLFEMLE_04363 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NMLFEMLE_04364 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NMLFEMLE_04365 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMLFEMLE_04366 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMLFEMLE_04367 1.1e-116 yknW S Yip1 domain
NMLFEMLE_04368 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMLFEMLE_04369 2.5e-124 macB V ABC transporter, ATP-binding protein
NMLFEMLE_04370 7.3e-209 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NMLFEMLE_04371 1.4e-42 fruR K Transcriptional regulator
NMLFEMLE_04372 1.7e-75 fruR K Transcriptional regulator
NMLFEMLE_04373 2.3e-13 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NMLFEMLE_04374 4.8e-137 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NMLFEMLE_04375 8.8e-291 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NMLFEMLE_04376 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NMLFEMLE_04377 8.1e-39 ykoA
NMLFEMLE_04378 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NMLFEMLE_04379 1.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NMLFEMLE_04380 4.5e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NMLFEMLE_04381 1.1e-12 S Uncharacterized protein YkpC
NMLFEMLE_04382 7.7e-183 mreB D Rod-share determining protein MreBH
NMLFEMLE_04383 1.5e-43 abrB K of stationary sporulation gene expression
NMLFEMLE_04384 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NMLFEMLE_04385 1.2e-157 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NMLFEMLE_04386 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NMLFEMLE_04387 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NMLFEMLE_04388 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMLFEMLE_04389 8.2e-31 ykzG S Belongs to the UPF0356 family
NMLFEMLE_04390 1.6e-146 ykrA S hydrolases of the HAD superfamily
NMLFEMLE_04391 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NMLFEMLE_04393 4.6e-109 recN L Putative cell-wall binding lipoprotein
NMLFEMLE_04394 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NMLFEMLE_04395 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMLFEMLE_04396 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMLFEMLE_04397 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NMLFEMLE_04398 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NMLFEMLE_04399 2.7e-10 S SR1 protein
NMLFEMLE_04400 2.2e-276 speA 4.1.1.19 E Arginine
NMLFEMLE_04401 1.6e-42 yktA S Belongs to the UPF0223 family
NMLFEMLE_04402 2.3e-116 yktB S Belongs to the UPF0637 family
NMLFEMLE_04403 7.1e-26 ykzI
NMLFEMLE_04404 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
NMLFEMLE_04405 5.8e-77 ykzC S Acetyltransferase (GNAT) family
NMLFEMLE_04406 4.6e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NMLFEMLE_04407 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NMLFEMLE_04408 0.0 ylaA
NMLFEMLE_04409 1.9e-40 ylaB
NMLFEMLE_04410 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NMLFEMLE_04411 3.5e-11 sigC S Putative zinc-finger
NMLFEMLE_04412 3.8e-36 ylaE
NMLFEMLE_04413 8.2e-22 S Family of unknown function (DUF5325)
NMLFEMLE_04414 7e-40 typA T GTP-binding protein TypA
NMLFEMLE_04415 1.6e-293 typA T GTP-binding protein TypA
NMLFEMLE_04416 4.2e-47 ylaH S YlaH-like protein
NMLFEMLE_04417 2.5e-32 ylaI S protein conserved in bacteria
NMLFEMLE_04418 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMLFEMLE_04419 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NMLFEMLE_04420 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NMLFEMLE_04421 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NMLFEMLE_04422 8.7e-44 ylaN S Belongs to the UPF0358 family
NMLFEMLE_04423 1.9e-212 ftsW D Belongs to the SEDS family
NMLFEMLE_04424 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NMLFEMLE_04425 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NMLFEMLE_04426 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NMLFEMLE_04427 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NMLFEMLE_04428 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NMLFEMLE_04429 2.8e-111 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NMLFEMLE_04430 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NMLFEMLE_04431 1.5e-166 ctaG S cytochrome c oxidase
NMLFEMLE_04432 7e-62 ylbA S YugN-like family
NMLFEMLE_04433 2.6e-74 ylbB T COG0517 FOG CBS domain
NMLFEMLE_04434 1.3e-199 ylbC S protein with SCP PR1 domains
NMLFEMLE_04435 3.3e-35 ylbD S Putative coat protein
NMLFEMLE_04436 6.7e-37 ylbE S YlbE-like protein
NMLFEMLE_04437 1.8e-75 ylbF S Belongs to the UPF0342 family
NMLFEMLE_04438 3.7e-38 ylbG S UPF0298 protein
NMLFEMLE_04439 9.5e-96 rsmD 2.1.1.171 L Methyltransferase
NMLFEMLE_04440 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
NMLFEMLE_04441 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
NMLFEMLE_04442 6.8e-187 ylbL T Belongs to the peptidase S16 family
NMLFEMLE_04443 1.5e-124 ylbM S Belongs to the UPF0348 family
NMLFEMLE_04444 1.2e-94 ylbM S Belongs to the UPF0348 family
NMLFEMLE_04446 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
NMLFEMLE_04447 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NMLFEMLE_04448 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NMLFEMLE_04449 1.5e-88 ylbP K n-acetyltransferase
NMLFEMLE_04450 4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NMLFEMLE_04451 2.1e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NMLFEMLE_04452 2.9e-78 mraZ K Belongs to the MraZ family
NMLFEMLE_04453 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NMLFEMLE_04454 3.7e-44 ftsL D Essential cell division protein
NMLFEMLE_04455 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NMLFEMLE_04456 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NMLFEMLE_04457 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NMLFEMLE_04458 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NMLFEMLE_04459 8.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NMLFEMLE_04460 5.7e-186 spoVE D Belongs to the SEDS family
NMLFEMLE_04461 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NMLFEMLE_04462 5.3e-167 murB 1.3.1.98 M cell wall formation
NMLFEMLE_04463 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NMLFEMLE_04464 4.1e-103 ylxW S protein conserved in bacteria
NMLFEMLE_04465 1.8e-91 ylxX S protein conserved in bacteria
NMLFEMLE_04466 6.2e-58 sbp S small basic protein
NMLFEMLE_04467 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NMLFEMLE_04468 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NMLFEMLE_04469 0.0 bpr O COG1404 Subtilisin-like serine proteases
NMLFEMLE_04470 2e-45 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NMLFEMLE_04471 2.7e-111 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NMLFEMLE_04472 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMLFEMLE_04473 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMLFEMLE_04474 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NMLFEMLE_04475 1.2e-249 argE 3.5.1.16 E Acetylornithine deacetylase
NMLFEMLE_04476 2.4e-37 ylmC S sporulation protein
NMLFEMLE_04477 2.3e-156 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NMLFEMLE_04478 2.5e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NMLFEMLE_04479 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NMLFEMLE_04480 1.3e-39 yggT S membrane
NMLFEMLE_04481 8.2e-115 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NMLFEMLE_04482 2.6e-67 divIVA D Cell division initiation protein
NMLFEMLE_04483 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NMLFEMLE_04484 1.3e-63 dksA T COG1734 DnaK suppressor protein
NMLFEMLE_04485 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NMLFEMLE_04486 1.9e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMLFEMLE_04487 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NMLFEMLE_04488 1.3e-230 pyrP F Xanthine uracil
NMLFEMLE_04489 1.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NMLFEMLE_04490 9.2e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NMLFEMLE_04491 4.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NMLFEMLE_04492 0.0 carB 6.3.5.5 F Belongs to the CarB family
NMLFEMLE_04493 1.2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NMLFEMLE_04494 2.1e-91 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NMLFEMLE_04495 3.4e-71 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NMLFEMLE_04496 3.3e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NMLFEMLE_04497 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NMLFEMLE_04499 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NMLFEMLE_04500 5.4e-179 cysP P phosphate transporter
NMLFEMLE_04501 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NMLFEMLE_04502 6.2e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NMLFEMLE_04503 8.8e-48 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NMLFEMLE_04504 1.1e-43 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NMLFEMLE_04505 4.9e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NMLFEMLE_04506 1.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NMLFEMLE_04507 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NMLFEMLE_04508 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NMLFEMLE_04509 2.4e-156 yloC S stress-induced protein
NMLFEMLE_04510 1.5e-40 ylzA S Belongs to the UPF0296 family
NMLFEMLE_04511 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NMLFEMLE_04512 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NMLFEMLE_04513 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NMLFEMLE_04514 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMLFEMLE_04515 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NMLFEMLE_04516 7.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NMLFEMLE_04517 2.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NMLFEMLE_04518 1.4e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NMLFEMLE_04519 1.6e-140 stp 3.1.3.16 T phosphatase
NMLFEMLE_04520 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NMLFEMLE_04521 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NMLFEMLE_04522 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NMLFEMLE_04523 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NMLFEMLE_04524 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NMLFEMLE_04525 5.5e-59 asp S protein conserved in bacteria
NMLFEMLE_04526 4.3e-300 yloV S kinase related to dihydroxyacetone kinase
NMLFEMLE_04527 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NMLFEMLE_04528 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NMLFEMLE_04529 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NMLFEMLE_04530 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NMLFEMLE_04531 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NMLFEMLE_04532 7.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NMLFEMLE_04533 6.1e-129 IQ reductase
NMLFEMLE_04534 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMLFEMLE_04535 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NMLFEMLE_04536 0.0 smc D Required for chromosome condensation and partitioning
NMLFEMLE_04537 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NMLFEMLE_04538 2.9e-87
NMLFEMLE_04539 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NMLFEMLE_04540 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NMLFEMLE_04541 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NMLFEMLE_04542 4.5e-36 ylqC S Belongs to the UPF0109 family
NMLFEMLE_04543 1.4e-60 ylqD S YlqD protein
NMLFEMLE_04544 2.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NMLFEMLE_04545 2.1e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NMLFEMLE_04546 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NMLFEMLE_04547 1.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NMLFEMLE_04548 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMLFEMLE_04549 5.9e-118 ylqG
NMLFEMLE_04550 4.5e-141 ylqG
NMLFEMLE_04551 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NMLFEMLE_04552 1e-182 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NMLFEMLE_04553 7.1e-15 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NMLFEMLE_04554 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NMLFEMLE_04555 7.9e-46 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NMLFEMLE_04556 1.5e-36 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NMLFEMLE_04557 4.7e-57 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NMLFEMLE_04558 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMLFEMLE_04559 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NMLFEMLE_04560 2.5e-169 xerC L tyrosine recombinase XerC
NMLFEMLE_04561 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NMLFEMLE_04562 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NMLFEMLE_04563 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NMLFEMLE_04564 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NMLFEMLE_04565 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
NMLFEMLE_04566 1.9e-31 fliE N Flagellar hook-basal body
NMLFEMLE_04567 2.6e-254 fliF N The M ring may be actively involved in energy transduction
NMLFEMLE_04568 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NMLFEMLE_04569 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NMLFEMLE_04570 9.4e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NMLFEMLE_04571 1.5e-69 fliJ N Flagellar biosynthesis chaperone
NMLFEMLE_04574 3.6e-202 fliK N Flagellar hook-length control protein
NMLFEMLE_04575 1.7e-72 flgD N Flagellar basal body rod modification protein
NMLFEMLE_04576 8.2e-140 flgG N Flagellar basal body rod
NMLFEMLE_04577 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NMLFEMLE_04578 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NMLFEMLE_04579 7.7e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NMLFEMLE_04580 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NMLFEMLE_04581 1.6e-96 fliZ N Flagellar biosynthesis protein, FliO
NMLFEMLE_04582 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NMLFEMLE_04583 2.2e-36 fliQ N Role in flagellar biosynthesis
NMLFEMLE_04584 3.6e-132 fliR N Flagellar biosynthetic protein FliR
NMLFEMLE_04585 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NMLFEMLE_04586 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NMLFEMLE_04587 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
NMLFEMLE_04588 7.5e-158 flhG D Belongs to the ParA family
NMLFEMLE_04589 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NMLFEMLE_04590 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NMLFEMLE_04591 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NMLFEMLE_04592 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NMLFEMLE_04593 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NMLFEMLE_04594 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMLFEMLE_04595 4.3e-78 ylxL
NMLFEMLE_04596 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NMLFEMLE_04597 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NMLFEMLE_04598 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NMLFEMLE_04599 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NMLFEMLE_04600 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NMLFEMLE_04601 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NMLFEMLE_04602 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NMLFEMLE_04603 7.7e-233 rasP M zinc metalloprotease
NMLFEMLE_04604 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NMLFEMLE_04605 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMLFEMLE_04606 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NMLFEMLE_04607 1.1e-203 nusA K Participates in both transcription termination and antitermination
NMLFEMLE_04608 4e-33 ylxR K nucleic-acid-binding protein implicated in transcription termination
NMLFEMLE_04609 3.1e-47 ylxQ J ribosomal protein
NMLFEMLE_04610 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NMLFEMLE_04611 3.9e-44 ylxP S protein conserved in bacteria
NMLFEMLE_04612 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NMLFEMLE_04613 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NMLFEMLE_04614 2e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NMLFEMLE_04615 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NMLFEMLE_04616 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NMLFEMLE_04617 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NMLFEMLE_04618 4.4e-233 pepR S Belongs to the peptidase M16 family
NMLFEMLE_04619 2.6e-42 ymxH S YlmC YmxH family
NMLFEMLE_04620 6.6e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NMLFEMLE_04621 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NMLFEMLE_04622 2.1e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NMLFEMLE_04623 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NMLFEMLE_04624 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NMLFEMLE_04625 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMLFEMLE_04626 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NMLFEMLE_04627 4.4e-32 S YlzJ-like protein
NMLFEMLE_04628 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NMLFEMLE_04629 1.4e-133 ymfC K Transcriptional regulator
NMLFEMLE_04630 3.8e-205 ymfD EGP Major facilitator Superfamily
NMLFEMLE_04631 2e-233 ymfF S Peptidase M16
NMLFEMLE_04632 4.1e-242 ymfH S zinc protease
NMLFEMLE_04633 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NMLFEMLE_04634 1.8e-40 ymfJ S Protein of unknown function (DUF3243)
NMLFEMLE_04635 2.7e-143 ymfK S Protein of unknown function (DUF3388)
NMLFEMLE_04636 1.9e-124 ymfM S protein conserved in bacteria
NMLFEMLE_04637 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NMLFEMLE_04638 9.6e-236 cinA 3.5.1.42 S Belongs to the CinA family
NMLFEMLE_04639 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NMLFEMLE_04640 9.7e-214 pbpX V Beta-lactamase
NMLFEMLE_04641 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NMLFEMLE_04642 1.9e-152 ymdB S protein conserved in bacteria
NMLFEMLE_04643 1.2e-36 spoVS S Stage V sporulation protein S
NMLFEMLE_04644 2.1e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NMLFEMLE_04645 2.3e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NMLFEMLE_04646 5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NMLFEMLE_04647 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NMLFEMLE_04648 2.2e-88 cotE S Spore coat protein
NMLFEMLE_04649 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NMLFEMLE_04650 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NMLFEMLE_04651 4.4e-69 S Regulatory protein YrvL
NMLFEMLE_04653 1.1e-95 ymcC S Membrane
NMLFEMLE_04654 2.4e-107 pksA K Transcriptional regulator
NMLFEMLE_04655 6.3e-125 pksB 3.1.2.6 S Polyketide biosynthesis
NMLFEMLE_04656 1.2e-160 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NMLFEMLE_04658 1.6e-182 pksD Q Acyl transferase domain
NMLFEMLE_04659 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NMLFEMLE_04660 1.4e-37 acpK IQ Phosphopantetheine attachment site
NMLFEMLE_04661 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NMLFEMLE_04662 7.4e-244 pksG 2.3.3.10 I synthase
NMLFEMLE_04663 2.7e-140 pksH 4.2.1.18 I enoyl-CoA hydratase
NMLFEMLE_04664 1e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NMLFEMLE_04665 0.0 rhiB IQ polyketide synthase
NMLFEMLE_04666 0.0 rhiB IQ polyketide synthase
NMLFEMLE_04667 0.0 pfaA Q Polyketide synthase of type I
NMLFEMLE_04668 2e-266 pfaA Q Polyketide synthase of type I
NMLFEMLE_04669 1.4e-98 pfaA Q Polyketide synthase of type I
NMLFEMLE_04670 0.0 pfaA Q Polyketide synthase of type I
NMLFEMLE_04671 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
NMLFEMLE_04672 0.0 dhbF IQ polyketide synthase
NMLFEMLE_04673 0.0 pks13 HQ Beta-ketoacyl synthase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)