ORF_ID e_value Gene_name EC_number CAZy COGs Description
OICMKCED_00001 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OICMKCED_00002 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OICMKCED_00003 1.8e-37 yaaB S Domain of unknown function (DUF370)
OICMKCED_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OICMKCED_00005 2.4e-33 yaaA S S4 domain
OICMKCED_00006 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OICMKCED_00007 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OICMKCED_00008 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
OICMKCED_00009 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OICMKCED_00010 6.5e-108 jag S single-stranded nucleic acid binding R3H
OICMKCED_00011 1.2e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OICMKCED_00012 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OICMKCED_00013 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
OICMKCED_00014 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
OICMKCED_00015 9.6e-74 S Bacterial PH domain
OICMKCED_00016 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
OICMKCED_00017 6e-149 spo0J K Belongs to the ParB family
OICMKCED_00018 2.8e-111 yyaC S Sporulation protein YyaC
OICMKCED_00019 1.8e-176 yyaD S Membrane
OICMKCED_00020 2.3e-33 yyzM S protein conserved in bacteria
OICMKCED_00021 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OICMKCED_00022 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OICMKCED_00023 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
OICMKCED_00024 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OICMKCED_00025 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OICMKCED_00026 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
OICMKCED_00027 3.6e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
OICMKCED_00028 8.9e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OICMKCED_00029 8.1e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
OICMKCED_00030 2.6e-242 EGP Major facilitator superfamily
OICMKCED_00031 8e-168 yyaK S CAAX protease self-immunity
OICMKCED_00032 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
OICMKCED_00033 4.1e-248 tetL EGP Major facilitator Superfamily
OICMKCED_00034 4e-104 yyaP 1.5.1.3 H RibD C-terminal domain
OICMKCED_00035 1.3e-65 yyaQ S YjbR
OICMKCED_00036 1.6e-91 yyaR K Acetyltransferase (GNAT) domain
OICMKCED_00037 5.5e-96 yyaS S Membrane
OICMKCED_00038 2e-71 yjcF S Acetyltransferase (GNAT) domain
OICMKCED_00039 5.6e-77 yybA 2.3.1.57 K transcriptional
OICMKCED_00040 2.8e-125 S Metallo-beta-lactamase superfamily
OICMKCED_00041 2.8e-74 yybC
OICMKCED_00042 1.4e-77 yjcF S Acetyltransferase (GNAT) domain
OICMKCED_00043 2.6e-163 yybE K Transcriptional regulator
OICMKCED_00044 3.1e-215 ynfM EGP Major facilitator Superfamily
OICMKCED_00045 1.6e-122 yybG S Pentapeptide repeat-containing protein
OICMKCED_00046 2.9e-66 yybH S SnoaL-like domain
OICMKCED_00047 2.8e-124
OICMKCED_00048 6.3e-110 K TipAS antibiotic-recognition domain
OICMKCED_00049 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
OICMKCED_00051 1.5e-58
OICMKCED_00052 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
OICMKCED_00053 7.5e-67 ydeP3 K Transcriptional regulator
OICMKCED_00054 3.3e-83 cotF M Spore coat protein
OICMKCED_00056 8.3e-160 yybS S membrane
OICMKCED_00057 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OICMKCED_00058 2.2e-73 rplI J binds to the 23S rRNA
OICMKCED_00059 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OICMKCED_00060 8.4e-221 yeaN P COG2807 Cyanate permease
OICMKCED_00061 1.9e-15 yycC K YycC-like protein
OICMKCED_00063 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
OICMKCED_00064 1.2e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OICMKCED_00065 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OICMKCED_00066 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OICMKCED_00071 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OICMKCED_00072 0.0 vicK 2.7.13.3 T Histidine kinase
OICMKCED_00073 1.2e-258 yycH S protein conserved in bacteria
OICMKCED_00074 5.2e-153 yycI S protein conserved in bacteria
OICMKCED_00075 4.3e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
OICMKCED_00076 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OICMKCED_00077 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
OICMKCED_00078 1.2e-40 sdpR K transcriptional
OICMKCED_00079 1.1e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
OICMKCED_00080 5.1e-40 S Sporulation delaying protein SdpA
OICMKCED_00081 9.6e-95
OICMKCED_00082 7.4e-16
OICMKCED_00083 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
OICMKCED_00084 1.3e-260 rocE E amino acid
OICMKCED_00085 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
OICMKCED_00087 1.5e-187 S aspartate phosphatase
OICMKCED_00088 8.4e-84 yycN 2.3.1.128 K Acetyltransferase
OICMKCED_00089 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OICMKCED_00090 6.2e-221 yycP
OICMKCED_00091 2.1e-33 yycQ S Protein of unknown function (DUF2651)
OICMKCED_00093 1.1e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OICMKCED_00094 6.5e-64
OICMKCED_00095 1.1e-09 S YyzF-like protein
OICMKCED_00096 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OICMKCED_00097 2e-163 L Reverse transcriptase (RNA-dependent DNA polymerase)
OICMKCED_00098 8e-132 S AIPR protein
OICMKCED_00099 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
OICMKCED_00100 2.7e-45 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
OICMKCED_00102 3.8e-287 ahpF O Alkyl hydroperoxide reductase
OICMKCED_00103 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
OICMKCED_00104 2.5e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OICMKCED_00105 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
OICMKCED_00106 3.3e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
OICMKCED_00107 7.3e-127 gntR K transcriptional
OICMKCED_00108 9.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OICMKCED_00109 1.4e-192 yxaB GM Polysaccharide pyruvyl transferase
OICMKCED_00110 1.3e-117 yxaC M effector of murein hydrolase
OICMKCED_00111 5.2e-50 S LrgA family
OICMKCED_00112 9.8e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
OICMKCED_00113 9.5e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OICMKCED_00114 2.7e-100 yxaF K Transcriptional regulator
OICMKCED_00115 1.9e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
OICMKCED_00116 1.5e-225 P Protein of unknown function (DUF418)
OICMKCED_00117 1.4e-75 yxaI S membrane protein domain
OICMKCED_00118 7.2e-60 S Family of unknown function (DUF5391)
OICMKCED_00119 6.8e-93 S PQQ-like domain
OICMKCED_00120 4e-12 yxaI S membrane protein domain
OICMKCED_00121 1.3e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
OICMKCED_00122 2.7e-208 yxbF K Bacterial regulatory proteins, tetR family
OICMKCED_00123 2.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
OICMKCED_00125 0.0 htpG O Molecular chaperone. Has ATPase activity
OICMKCED_00126 2.1e-244 csbC EGP Major facilitator Superfamily
OICMKCED_00127 8.3e-48 yxcD S Protein of unknown function (DUF2653)
OICMKCED_00129 8.3e-176 iolS C Aldo keto reductase
OICMKCED_00130 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
OICMKCED_00131 8.8e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OICMKCED_00132 3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
OICMKCED_00133 3.2e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
OICMKCED_00134 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
OICMKCED_00135 2.3e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
OICMKCED_00136 1.6e-233 iolF EGP Major facilitator Superfamily
OICMKCED_00137 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
OICMKCED_00138 8.6e-167 iolH G Xylose isomerase-like TIM barrel
OICMKCED_00139 5.6e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
OICMKCED_00140 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
OICMKCED_00141 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OICMKCED_00142 2e-180 T PhoQ Sensor
OICMKCED_00143 9.4e-141 yxdL V ABC transporter, ATP-binding protein
OICMKCED_00144 0.0 yxdM V ABC transporter (permease)
OICMKCED_00145 3.4e-58 yxeA S Protein of unknown function (DUF1093)
OICMKCED_00146 6.6e-176 fhuD P ABC transporter
OICMKCED_00147 8.5e-69
OICMKCED_00148 9.6e-16 yxeD
OICMKCED_00149 1.3e-20 yxeE
OICMKCED_00152 4e-150 yidA S hydrolases of the HAD superfamily
OICMKCED_00153 4.3e-191 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
OICMKCED_00155 2.4e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OICMKCED_00156 2.3e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OICMKCED_00157 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
OICMKCED_00158 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
OICMKCED_00159 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
OICMKCED_00160 4.4e-211 yxeP 3.5.1.47 E hydrolase activity
OICMKCED_00161 6.9e-248 yxeQ S MmgE/PrpD family
OICMKCED_00162 1.5e-195 eutH E Ethanolamine utilisation protein, EutH
OICMKCED_00163 1.1e-150 yxxB S Domain of Unknown Function (DUF1206)
OICMKCED_00164 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OICMKCED_00165 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OICMKCED_00166 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OICMKCED_00167 1.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
OICMKCED_00168 2e-250 lysP E amino acid
OICMKCED_00169 1.4e-178 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
OICMKCED_00170 1.7e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
OICMKCED_00171 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OICMKCED_00172 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
OICMKCED_00173 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
OICMKCED_00174 1.9e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OICMKCED_00175 4.6e-21 S Domain of unknown function (DUF5082)
OICMKCED_00176 1.8e-38 yxiC S Family of unknown function (DUF5344)
OICMKCED_00177 3.6e-310 S nuclease activity
OICMKCED_00178 2.2e-78 S SMI1 / KNR4 family
OICMKCED_00179 5.7e-306 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OICMKCED_00180 1.3e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OICMKCED_00181 9.2e-72 yxiE T Belongs to the universal stress protein A family
OICMKCED_00182 5.6e-164 yxxF EG EamA-like transporter family
OICMKCED_00183 0.0 wapA M COG3209 Rhs family protein
OICMKCED_00184 1.5e-71 yxxG
OICMKCED_00185 3.8e-84
OICMKCED_00186 7.3e-59
OICMKCED_00187 5.1e-69 yxiG
OICMKCED_00188 3.3e-139
OICMKCED_00189 6.3e-82 yxiI S Protein of unknown function (DUF2716)
OICMKCED_00190 4.7e-40 yxiJ S YxiJ-like protein
OICMKCED_00193 8.9e-212 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
OICMKCED_00194 2.1e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
OICMKCED_00195 5.6e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
OICMKCED_00196 4.7e-112
OICMKCED_00197 8.3e-151 licT K transcriptional antiterminator
OICMKCED_00198 7.3e-143 exoK GH16 M licheninase activity
OICMKCED_00199 6.6e-224 citH C Citrate transporter
OICMKCED_00200 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
OICMKCED_00201 8.7e-47 yxiS
OICMKCED_00202 5.7e-102 T Domain of unknown function (DUF4163)
OICMKCED_00203 7.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OICMKCED_00204 1.6e-157 rlmA 2.1.1.187 Q Methyltransferase domain
OICMKCED_00205 3.7e-252 yxjC EG COG2610 H gluconate symporter and related permeases
OICMKCED_00206 6.9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OICMKCED_00207 1.2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OICMKCED_00208 2.4e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
OICMKCED_00209 8.2e-218 yxjG 2.1.1.14 E Methionine synthase
OICMKCED_00210 6.7e-220 yxjG 2.1.1.14 E Methionine synthase
OICMKCED_00211 1.3e-84 yxjI S LURP-one-related
OICMKCED_00213 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OICMKCED_00214 7.1e-113 K helix_turn_helix, Lux Regulon
OICMKCED_00215 1.6e-190 yxjM T Signal transduction histidine kinase
OICMKCED_00216 7.7e-77 S Protein of unknown function (DUF1453)
OICMKCED_00217 5.7e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OICMKCED_00218 4.4e-137
OICMKCED_00219 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OICMKCED_00220 2e-269 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OICMKCED_00221 5.4e-164 lrp QT PucR C-terminal helix-turn-helix domain
OICMKCED_00222 5.9e-205 msmK P Belongs to the ABC transporter superfamily
OICMKCED_00223 4.7e-154 yxkH G Polysaccharide deacetylase
OICMKCED_00225 1.3e-307 3.4.24.84 O Peptidase family M48
OICMKCED_00226 2.1e-228 cimH C COG3493 Na citrate symporter
OICMKCED_00227 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
OICMKCED_00228 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
OICMKCED_00229 9.4e-311 cydD V ATP-binding
OICMKCED_00230 0.0 cydD V ATP-binding protein
OICMKCED_00231 7.7e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OICMKCED_00232 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
OICMKCED_00233 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
OICMKCED_00234 1.9e-47 yxlC S Family of unknown function (DUF5345)
OICMKCED_00235 1.4e-30
OICMKCED_00236 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
OICMKCED_00237 2.4e-164 yxlF V ABC transporter, ATP-binding protein
OICMKCED_00238 2.8e-137 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OICMKCED_00239 1.7e-210 yxlH EGP Major facilitator Superfamily
OICMKCED_00240 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OICMKCED_00241 2.9e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
OICMKCED_00242 1.1e-19 yxzF
OICMKCED_00243 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
OICMKCED_00244 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
OICMKCED_00245 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OICMKCED_00246 1.9e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
OICMKCED_00247 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OICMKCED_00248 6.9e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OICMKCED_00249 2.8e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
OICMKCED_00250 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OICMKCED_00251 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OICMKCED_00252 1.2e-232 dltB M membrane protein involved in D-alanine export
OICMKCED_00253 7.4e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OICMKCED_00254 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
OICMKCED_00255 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
OICMKCED_00256 1e-130 ynfM EGP Major facilitator Superfamily
OICMKCED_00257 2.1e-48 4.1.1.44 S Carboxymuconolactone decarboxylase family
OICMKCED_00258 5.3e-92 K Helix-turn-helix XRE-family like proteins
OICMKCED_00259 4.9e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
OICMKCED_00260 1.7e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OICMKCED_00261 2.3e-87 ywaE K Transcriptional regulator
OICMKCED_00262 2.5e-124 ywaF S Integral membrane protein
OICMKCED_00263 4.5e-168 gspA M General stress
OICMKCED_00264 2.1e-149 sacY K transcriptional antiterminator
OICMKCED_00265 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OICMKCED_00266 4.9e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
OICMKCED_00267 5.6e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OICMKCED_00268 5.9e-123 ywbB S Protein of unknown function (DUF2711)
OICMKCED_00269 2.6e-95 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
OICMKCED_00270 4.9e-66 ywbC 4.4.1.5 E glyoxalase
OICMKCED_00271 2e-219 ywbD 2.1.1.191 J Methyltransferase
OICMKCED_00272 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
OICMKCED_00273 8.1e-208 ywbF EGP Major facilitator Superfamily
OICMKCED_00274 2.3e-111 ywbG M effector of murein hydrolase
OICMKCED_00275 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
OICMKCED_00276 4.3e-153 ywbI K Transcriptional regulator
OICMKCED_00277 8.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OICMKCED_00278 7.2e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
OICMKCED_00279 4.5e-253 P COG0672 High-affinity Fe2 Pb2 permease
OICMKCED_00280 2.9e-186 ycdO P periplasmic lipoprotein involved in iron transport
OICMKCED_00281 2.6e-225 ywbN P Dyp-type peroxidase family protein
OICMKCED_00282 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OICMKCED_00283 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OICMKCED_00284 1.1e-47 ywcB S Protein of unknown function, DUF485
OICMKCED_00286 2.2e-122 ywcC K transcriptional regulator
OICMKCED_00287 9.5e-60 gtcA S GtrA-like protein
OICMKCED_00288 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OICMKCED_00289 1.3e-303 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OICMKCED_00290 1e-35 ywzA S membrane
OICMKCED_00291 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
OICMKCED_00292 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OICMKCED_00293 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OICMKCED_00294 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OICMKCED_00295 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
OICMKCED_00296 8.6e-202 rodA D Belongs to the SEDS family
OICMKCED_00297 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
OICMKCED_00298 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OICMKCED_00299 0.0 vpr O Belongs to the peptidase S8 family
OICMKCED_00301 7e-150 sacT K transcriptional antiterminator
OICMKCED_00302 1e-139 focA P Formate/nitrite transporter
OICMKCED_00303 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OICMKCED_00304 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
OICMKCED_00305 2e-28 ywdA
OICMKCED_00306 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OICMKCED_00307 6.1e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
OICMKCED_00308 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OICMKCED_00309 4.7e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
OICMKCED_00310 5e-48 ywdI S Family of unknown function (DUF5327)
OICMKCED_00311 3.7e-238 ywdJ F Xanthine uracil
OICMKCED_00312 4.3e-59 ywdK S small membrane protein
OICMKCED_00313 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
OICMKCED_00314 1.8e-144 spsA M Spore Coat
OICMKCED_00315 2.6e-266 spsB M Capsule polysaccharide biosynthesis protein
OICMKCED_00316 3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
OICMKCED_00317 1.2e-163 spsD 2.3.1.210 K Spore Coat
OICMKCED_00318 3.3e-211 spsE 2.5.1.56 M acid synthase
OICMKCED_00319 5e-128 spsF M Spore Coat
OICMKCED_00320 9.7e-186 spsG M Spore Coat
OICMKCED_00321 9.3e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OICMKCED_00322 1.1e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
OICMKCED_00323 3.2e-158 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
OICMKCED_00324 3.5e-87 spsL 5.1.3.13 M Spore Coat
OICMKCED_00325 1.2e-77
OICMKCED_00326 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OICMKCED_00327 6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OICMKCED_00328 0.0 rocB E arginine degradation protein
OICMKCED_00329 8.2e-249 lysP E amino acid
OICMKCED_00330 1.3e-205 ywfA EGP Major facilitator Superfamily
OICMKCED_00331 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
OICMKCED_00332 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
OICMKCED_00333 1.1e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OICMKCED_00334 4e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
OICMKCED_00335 7.3e-209 bacE EGP Major facilitator Superfamily
OICMKCED_00336 1.6e-232 ywfG 2.6.1.83 E Aminotransferase class I and II
OICMKCED_00337 2.2e-137 IQ Enoyl-(Acyl carrier protein) reductase
OICMKCED_00338 1.1e-146 ywfI C May function as heme-dependent peroxidase
OICMKCED_00339 1.6e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
OICMKCED_00340 1.1e-156 cysL K Transcriptional regulator
OICMKCED_00341 5.6e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
OICMKCED_00342 9.2e-156 ywfM EG EamA-like transporter family
OICMKCED_00343 5.1e-110 rsfA_1
OICMKCED_00344 3.1e-36 ywzC S Belongs to the UPF0741 family
OICMKCED_00345 5.1e-256 ywfO S COG1078 HD superfamily phosphohydrolases
OICMKCED_00346 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
OICMKCED_00347 6.9e-78 yffB K Transcriptional regulator
OICMKCED_00348 9.7e-237 mmr U Major Facilitator Superfamily
OICMKCED_00350 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OICMKCED_00351 9.5e-71 ywhA K Transcriptional regulator
OICMKCED_00352 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
OICMKCED_00353 5.1e-119 ywhC S Peptidase family M50
OICMKCED_00354 3.4e-94 ywhD S YwhD family
OICMKCED_00355 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OICMKCED_00356 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OICMKCED_00357 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
OICMKCED_00359 1.4e-57 V ATPases associated with a variety of cellular activities
OICMKCED_00362 1.7e-20
OICMKCED_00366 2e-78 S aspartate phosphatase
OICMKCED_00367 2.7e-191 ywhK CO amine dehydrogenase activity
OICMKCED_00368 1.8e-243 ywhL CO amine dehydrogenase activity
OICMKCED_00370 1e-248 L Peptidase, M16
OICMKCED_00371 8.5e-218 2.7.1.26, 2.7.7.2 L Peptidase, M16
OICMKCED_00372 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
OICMKCED_00373 3.3e-132 cbiO V ABC transporter
OICMKCED_00375 1.3e-270 C Fe-S oxidoreductases
OICMKCED_00376 1e-07 S Bacteriocin subtilosin A
OICMKCED_00377 4.7e-73 ywiB S protein conserved in bacteria
OICMKCED_00378 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
OICMKCED_00379 9.8e-214 narK P COG2223 Nitrate nitrite transporter
OICMKCED_00380 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
OICMKCED_00381 1.7e-139 ywiC S YwiC-like protein
OICMKCED_00382 7e-86 arfM T cyclic nucleotide binding
OICMKCED_00383 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OICMKCED_00384 1.9e-296 narH 1.7.5.1 C Nitrate reductase, beta
OICMKCED_00385 2.4e-93 narJ 1.7.5.1 C nitrate reductase
OICMKCED_00386 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
OICMKCED_00387 3.5e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OICMKCED_00388 0.0 ywjA V ABC transporter
OICMKCED_00389 4.8e-96 ywjB H RibD C-terminal domain
OICMKCED_00390 2.7e-42 ywjC
OICMKCED_00391 2.1e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
OICMKCED_00392 6.8e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
OICMKCED_00393 0.0 fadF C COG0247 Fe-S oxidoreductase
OICMKCED_00394 9.7e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
OICMKCED_00395 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OICMKCED_00396 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OICMKCED_00397 2.3e-90 ywjG S Domain of unknown function (DUF2529)
OICMKCED_00398 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
OICMKCED_00399 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
OICMKCED_00400 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OICMKCED_00401 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OICMKCED_00402 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
OICMKCED_00403 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OICMKCED_00404 1.1e-32 rpmE J Binds the 23S rRNA
OICMKCED_00405 7e-104 tdk 2.7.1.21 F thymidine kinase
OICMKCED_00406 0.0 sfcA 1.1.1.38 C malic enzyme
OICMKCED_00407 8.6e-160 ywkB S Membrane transport protein
OICMKCED_00408 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
OICMKCED_00409 3.8e-66 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OICMKCED_00410 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OICMKCED_00411 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OICMKCED_00413 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
OICMKCED_00414 3e-111 spoIIR S stage II sporulation protein R
OICMKCED_00415 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
OICMKCED_00416 3.1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OICMKCED_00417 1.7e-91 mntP P Probably functions as a manganese efflux pump
OICMKCED_00418 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OICMKCED_00419 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
OICMKCED_00420 7.2e-95 ywlG S Belongs to the UPF0340 family
OICMKCED_00421 4.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OICMKCED_00422 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OICMKCED_00423 2.5e-62 atpI S ATP synthase
OICMKCED_00424 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
OICMKCED_00425 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OICMKCED_00426 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OICMKCED_00427 3.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OICMKCED_00428 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OICMKCED_00429 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OICMKCED_00430 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OICMKCED_00431 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OICMKCED_00432 3.1e-86 ywmA
OICMKCED_00433 1.3e-32 ywzB S membrane
OICMKCED_00434 8.5e-131 ywmB S TATA-box binding
OICMKCED_00435 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OICMKCED_00436 3.5e-175 spoIID D Stage II sporulation protein D
OICMKCED_00437 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
OICMKCED_00438 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
OICMKCED_00440 3.8e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OICMKCED_00441 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OICMKCED_00442 1.3e-103 S response regulator aspartate phosphatase
OICMKCED_00443 3e-84 ywmF S Peptidase M50
OICMKCED_00444 3.2e-10 csbD K CsbD-like
OICMKCED_00445 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
OICMKCED_00446 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
OICMKCED_00447 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
OICMKCED_00448 2.8e-64 ywnA K Transcriptional regulator
OICMKCED_00449 1.1e-113 ywnB S NAD(P)H-binding
OICMKCED_00450 2.6e-59 ywnC S Family of unknown function (DUF5362)
OICMKCED_00451 8.5e-142 mta K transcriptional
OICMKCED_00452 2.7e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OICMKCED_00453 2.2e-70 ywnF S Family of unknown function (DUF5392)
OICMKCED_00454 2.7e-14 ywnC S Family of unknown function (DUF5362)
OICMKCED_00455 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
OICMKCED_00456 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
OICMKCED_00457 2.4e-69 ywnJ S VanZ like family
OICMKCED_00458 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
OICMKCED_00459 1.6e-58 nrgB K Belongs to the P(II) protein family
OICMKCED_00460 3.3e-225 amt P Ammonium transporter
OICMKCED_00461 8.3e-76
OICMKCED_00462 1.5e-103 phzA Q Isochorismatase family
OICMKCED_00463 3.1e-240 ywoD EGP Major facilitator superfamily
OICMKCED_00464 4.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
OICMKCED_00465 1.4e-230 ywoF P Right handed beta helix region
OICMKCED_00466 7.8e-211 ywoG EGP Major facilitator Superfamily
OICMKCED_00467 2.1e-70 ywoH K COG1846 Transcriptional regulators
OICMKCED_00468 3e-44 spoIIID K Stage III sporulation protein D
OICMKCED_00469 3.5e-180 mbl D Rod shape-determining protein
OICMKCED_00470 1.5e-125 flhO N flagellar basal body
OICMKCED_00471 4.4e-141 flhP N flagellar basal body
OICMKCED_00472 7.5e-197 S aspartate phosphatase
OICMKCED_00473 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OICMKCED_00474 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
OICMKCED_00475 1.4e-145 ywpD T Histidine kinase
OICMKCED_00476 2.7e-46 srtA 3.4.22.70 M Sortase family
OICMKCED_00477 1.1e-66 ywpF S YwpF-like protein
OICMKCED_00478 3.8e-66 ywpG
OICMKCED_00479 1.4e-56 ssbB L Single-stranded DNA-binding protein
OICMKCED_00480 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
OICMKCED_00481 4.8e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
OICMKCED_00482 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OICMKCED_00483 1.3e-306 ywqB S SWIM zinc finger
OICMKCED_00484 1.2e-17
OICMKCED_00485 2e-116 ywqC M biosynthesis protein
OICMKCED_00486 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
OICMKCED_00487 7.4e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
OICMKCED_00488 3.4e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OICMKCED_00489 5.4e-152 ywqG S Domain of unknown function (DUF1963)
OICMKCED_00490 9.7e-23 S Domain of unknown function (DUF5082)
OICMKCED_00491 2.5e-37 ywqI S Family of unknown function (DUF5344)
OICMKCED_00492 1.6e-242 ywqJ S Pre-toxin TG
OICMKCED_00493 3.9e-25
OICMKCED_00494 6.7e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
OICMKCED_00495 4.2e-161 K Transcriptional regulator
OICMKCED_00496 1.1e-100 ywqN S NAD(P)H-dependent
OICMKCED_00498 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
OICMKCED_00499 1.2e-103 ywrB P Chromate transporter
OICMKCED_00500 8e-82 ywrC K Transcriptional regulator
OICMKCED_00501 1.4e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OICMKCED_00503 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OICMKCED_00504 3.7e-12
OICMKCED_00505 1.3e-209 cotH M Spore Coat
OICMKCED_00506 6.8e-131 cotB
OICMKCED_00507 3.1e-124 ywrJ
OICMKCED_00508 9.4e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OICMKCED_00509 1.1e-169 alsR K LysR substrate binding domain
OICMKCED_00510 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
OICMKCED_00511 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
OICMKCED_00512 4.4e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
OICMKCED_00513 8e-48 ywsA S Protein of unknown function (DUF3892)
OICMKCED_00514 3.1e-90 batE T Sh3 type 3 domain protein
OICMKCED_00515 1.2e-158 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
OICMKCED_00516 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
OICMKCED_00517 1.4e-273 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
OICMKCED_00518 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
OICMKCED_00519 1.9e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OICMKCED_00520 9.3e-178 rbsR K transcriptional
OICMKCED_00521 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
OICMKCED_00522 8.6e-70 pgsC S biosynthesis protein
OICMKCED_00523 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
OICMKCED_00524 3.6e-21 ywtC
OICMKCED_00525 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OICMKCED_00526 4.2e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
OICMKCED_00527 2.3e-168 ywtF K Transcriptional regulator
OICMKCED_00528 4.1e-248 ywtG EGP Major facilitator Superfamily
OICMKCED_00529 1.2e-197 gerAC S Spore germination protein
OICMKCED_00530 4.7e-186 gerBB E Spore germination protein
OICMKCED_00531 3.8e-244 gerBA EG Spore germination protein
OICMKCED_00532 2.5e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
OICMKCED_00533 4e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OICMKCED_00534 3.5e-171
OICMKCED_00535 4.3e-39
OICMKCED_00536 3.2e-214 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OICMKCED_00537 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OICMKCED_00538 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
OICMKCED_00539 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
OICMKCED_00540 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OICMKCED_00541 7e-150 tagG GM Transport permease protein
OICMKCED_00542 1.1e-257 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OICMKCED_00543 5.8e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OICMKCED_00544 5.5e-214 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
OICMKCED_00545 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OICMKCED_00546 6e-38
OICMKCED_00547 0.0 lytB 3.5.1.28 D Stage II sporulation protein
OICMKCED_00548 3.3e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OICMKCED_00549 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OICMKCED_00550 1.7e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OICMKCED_00551 2.5e-217 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
OICMKCED_00552 3.1e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OICMKCED_00553 1.4e-262 tuaE M Teichuronic acid biosynthesis protein
OICMKCED_00554 2.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
OICMKCED_00555 2.8e-145 tuaG GT2 M Glycosyltransferase like family 2
OICMKCED_00556 8.6e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
OICMKCED_00557 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
OICMKCED_00558 6e-163 yvhJ K Transcriptional regulator
OICMKCED_00559 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
OICMKCED_00560 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
OICMKCED_00561 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OICMKCED_00562 7.3e-155 degV S protein conserved in bacteria
OICMKCED_00563 6.2e-268 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OICMKCED_00564 3.7e-45 comFB S Late competence development protein ComFB
OICMKCED_00565 2e-124 comFC S Phosphoribosyl transferase domain
OICMKCED_00566 7e-74 yvyF S flagellar protein
OICMKCED_00567 7.2e-40 flgM KNU Negative regulator of flagellin synthesis
OICMKCED_00568 2.4e-78 flgN NOU FlgN protein
OICMKCED_00569 2.7e-264 flgK N flagellar hook-associated protein
OICMKCED_00570 7.8e-155 flgL N Belongs to the bacterial flagellin family
OICMKCED_00571 5.7e-50 yviE
OICMKCED_00572 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OICMKCED_00573 2.8e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OICMKCED_00574 1.4e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OICMKCED_00575 1.2e-55 flaG N flagellar protein FlaG
OICMKCED_00576 2e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OICMKCED_00577 1.1e-68 fliS N flagellar protein FliS
OICMKCED_00578 1.4e-08 fliT S bacterial-type flagellum organization
OICMKCED_00579 2.8e-66
OICMKCED_00580 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OICMKCED_00581 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OICMKCED_00582 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OICMKCED_00583 9.3e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
OICMKCED_00584 2e-55 cccB C COG2010 Cytochrome c, mono- and diheme variants
OICMKCED_00585 1.6e-123 ftsE D cell division ATP-binding protein FtsE
OICMKCED_00586 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
OICMKCED_00587 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
OICMKCED_00588 5.3e-56 swrA S Swarming motility protein
OICMKCED_00589 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OICMKCED_00590 3.3e-226 yvkA EGP Major facilitator Superfamily
OICMKCED_00591 1.6e-100 yvkB K Transcriptional regulator
OICMKCED_00592 0.0 yvkC 2.7.9.2 GT Phosphotransferase
OICMKCED_00593 1.2e-30 csbA S protein conserved in bacteria
OICMKCED_00594 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OICMKCED_00595 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OICMKCED_00596 8.2e-49 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OICMKCED_00597 5.7e-33 yvkN
OICMKCED_00598 8e-49 yvlA
OICMKCED_00599 2.4e-166 yvlB S Putative adhesin
OICMKCED_00600 2.6e-26 pspB KT PspC domain
OICMKCED_00601 1.2e-50 yvlD S Membrane
OICMKCED_00602 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
OICMKCED_00603 1.8e-133 yvoA K transcriptional
OICMKCED_00604 4.3e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OICMKCED_00605 3.9e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OICMKCED_00606 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OICMKCED_00607 2.7e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OICMKCED_00608 5.3e-162 yvoD P COG0370 Fe2 transport system protein B
OICMKCED_00609 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
OICMKCED_00610 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
OICMKCED_00611 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
OICMKCED_00612 3.8e-139 yvpB NU protein conserved in bacteria
OICMKCED_00613 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OICMKCED_00614 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
OICMKCED_00615 2.2e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OICMKCED_00616 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
OICMKCED_00617 6.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OICMKCED_00618 2.5e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OICMKCED_00619 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
OICMKCED_00620 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
OICMKCED_00621 4.6e-121
OICMKCED_00622 0.0
OICMKCED_00624 0.0 msbA2 3.6.3.44 V ABC transporter
OICMKCED_00625 1.2e-277 S COG0457 FOG TPR repeat
OICMKCED_00626 4.7e-98 usp CBM50 M protein conserved in bacteria
OICMKCED_00627 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OICMKCED_00628 1.5e-88 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OICMKCED_00629 5.7e-166 rapZ S Displays ATPase and GTPase activities
OICMKCED_00630 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
OICMKCED_00631 1.4e-170 whiA K May be required for sporulation
OICMKCED_00632 1.6e-36 crh G Phosphocarrier protein Chr
OICMKCED_00633 8.9e-144 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
OICMKCED_00634 1.9e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OICMKCED_00635 7.5e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
OICMKCED_00636 2.1e-140 yvcR V ABC transporter, ATP-binding protein
OICMKCED_00637 0.0 yxdM V ABC transporter (permease)
OICMKCED_00638 3.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OICMKCED_00639 6.3e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OICMKCED_00640 2.8e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
OICMKCED_00641 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
OICMKCED_00642 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
OICMKCED_00643 1e-173 yvdE K Transcriptional regulator
OICMKCED_00644 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
OICMKCED_00645 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
OICMKCED_00646 2.9e-243 malC P COG1175 ABC-type sugar transport systems, permease components
OICMKCED_00647 6.6e-148 malD P transport
OICMKCED_00648 2.2e-154 malA S Protein of unknown function (DUF1189)
OICMKCED_00649 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
OICMKCED_00650 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
OICMKCED_00651 2.3e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
OICMKCED_00652 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OICMKCED_00656 2.6e-38
OICMKCED_00657 1.3e-92 sdpB S Vitamin K-dependent gamma-carboxylase
OICMKCED_00658 1.5e-78 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
OICMKCED_00659 1.4e-181 S Patatin-like phospholipase
OICMKCED_00660 1.4e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
OICMKCED_00661 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
OICMKCED_00662 4.1e-50 sugE P Small Multidrug Resistance protein
OICMKCED_00663 7.4e-50 ykkC P Small Multidrug Resistance protein
OICMKCED_00664 2.6e-106 yvdT K Transcriptional regulator
OICMKCED_00665 1.8e-295 yveA E amino acid
OICMKCED_00666 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
OICMKCED_00667 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
OICMKCED_00668 4.5e-57 pbpE V Beta-lactamase
OICMKCED_00669 2.2e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
OICMKCED_00670 9.3e-72 MA20_18690 S Protein of unknown function (DUF3237)
OICMKCED_00671 4.6e-93 padC Q Phenolic acid decarboxylase
OICMKCED_00673 1.3e-136 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
OICMKCED_00674 4.4e-132 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
OICMKCED_00675 6.3e-76 slr K transcriptional
OICMKCED_00676 4e-122 ywqC M biosynthesis protein
OICMKCED_00677 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
OICMKCED_00678 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
OICMKCED_00679 2.5e-222 epsD GT4 M Glycosyl transferase 4-like
OICMKCED_00680 1.6e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OICMKCED_00681 3.5e-216 epsF GT4 M Glycosyl transferases group 1
OICMKCED_00682 1.1e-206 epsG S EpsG family
OICMKCED_00683 5.8e-194 epsH GT2 S Glycosyltransferase like family 2
OICMKCED_00684 4.4e-205 epsI GM pyruvyl transferase
OICMKCED_00685 3.3e-189 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
OICMKCED_00686 2.4e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OICMKCED_00687 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OICMKCED_00688 1.3e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
OICMKCED_00689 7.4e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OICMKCED_00690 9.2e-186 yvfF GM Exopolysaccharide biosynthesis protein
OICMKCED_00691 1e-31 yvfG S YvfG protein
OICMKCED_00692 1.1e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
OICMKCED_00693 2.6e-308 yvfH C L-lactate permease
OICMKCED_00694 2.7e-113 yvfI K COG2186 Transcriptional regulators
OICMKCED_00695 1.8e-184 lacR K Transcriptional regulator
OICMKCED_00696 1.5e-231 cycB G COG2182 Maltose-binding periplasmic proteins domains
OICMKCED_00697 5.5e-231 malC P COG1175 ABC-type sugar transport systems, permease components
OICMKCED_00698 7.2e-150 ganQ P transport
OICMKCED_00699 0.0 lacA 3.2.1.23 G beta-galactosidase
OICMKCED_00700 1.7e-248 galA 3.2.1.89 G arabinogalactan
OICMKCED_00701 4.1e-199 rsbU 3.1.3.3 T response regulator
OICMKCED_00702 9.8e-157 rsbQ S Alpha/beta hydrolase family
OICMKCED_00703 2.6e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
OICMKCED_00704 1.4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
OICMKCED_00705 5.6e-195 desK 2.7.13.3 T Histidine kinase
OICMKCED_00706 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OICMKCED_00707 5.9e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OICMKCED_00708 1e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
OICMKCED_00709 1.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OICMKCED_00710 3.4e-194 yvbX S Glycosyl hydrolase
OICMKCED_00711 1.2e-239 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
OICMKCED_00712 2.7e-155 yvbV EG EamA-like transporter family
OICMKCED_00713 5.1e-159 yvbU K Transcriptional regulator
OICMKCED_00714 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OICMKCED_00715 5.5e-203 araR K transcriptional
OICMKCED_00716 1.6e-252 araE EGP Major facilitator Superfamily
OICMKCED_00717 1.8e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OICMKCED_00718 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OICMKCED_00719 6.5e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OICMKCED_00720 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OICMKCED_00721 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
OICMKCED_00722 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OICMKCED_00723 1.1e-165 ywaD 3.4.11.10, 3.4.11.6 S PA domain
OICMKCED_00724 2.8e-217 1.1.1.136 M UDP binding domain
OICMKCED_00725 1.8e-185 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OICMKCED_00726 9.6e-148 5.1.3.2 M GDP-mannose 4,6 dehydratase
OICMKCED_00727 1.1e-156 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OICMKCED_00728 7.6e-114 M Protein involved in cellulose biosynthesis
OICMKCED_00729 1.4e-122 C WbqC-like protein family
OICMKCED_00730 2.3e-114 S GlcNAc-PI de-N-acetylase
OICMKCED_00731 3.7e-152
OICMKCED_00732 2.7e-174 EGP Major facilitator Superfamily
OICMKCED_00733 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
OICMKCED_00734 0.0 tcaA S response to antibiotic
OICMKCED_00735 1e-122 exoY M Membrane
OICMKCED_00736 1.9e-112 yvbH S YvbH-like oligomerisation region
OICMKCED_00737 1.9e-102 yvbG U UPF0056 membrane protein
OICMKCED_00738 3.5e-97 yvbF K Belongs to the GbsR family
OICMKCED_00739 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OICMKCED_00740 2.3e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OICMKCED_00741 2.3e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OICMKCED_00742 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OICMKCED_00743 3.3e-60 yvbF K Belongs to the GbsR family
OICMKCED_00744 9.2e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OICMKCED_00745 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OICMKCED_00746 4.8e-168 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OICMKCED_00747 4.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OICMKCED_00748 1.9e-218 NT chemotaxis protein
OICMKCED_00749 2.2e-54 yodB K transcriptional
OICMKCED_00750 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
OICMKCED_00751 4e-69 K transcriptional
OICMKCED_00752 7.5e-36 yvzC K Transcriptional
OICMKCED_00753 3.8e-150 yvaM S Serine aminopeptidase, S33
OICMKCED_00754 2.4e-23 secG U Preprotein translocase subunit SecG
OICMKCED_00755 5.6e-143 est 3.1.1.1 S Carboxylesterase
OICMKCED_00756 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OICMKCED_00757 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OICMKCED_00759 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OICMKCED_00760 1.2e-97 K Bacterial regulatory proteins, tetR family
OICMKCED_00761 6.3e-55 yvaE P Small Multidrug Resistance protein
OICMKCED_00762 5.7e-73 yvaD S Family of unknown function (DUF5360)
OICMKCED_00763 0.0 yvaC S Fusaric acid resistance protein-like
OICMKCED_00764 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OICMKCED_00765 1.1e-195 yvaA 1.1.1.371 S Oxidoreductase
OICMKCED_00766 2.2e-48 csoR S transcriptional
OICMKCED_00767 5.9e-29 copZ P Copper resistance protein CopZ
OICMKCED_00768 0.0 copA 3.6.3.54 P P-type ATPase
OICMKCED_00769 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OICMKCED_00770 1.6e-104 bdbD O Thioredoxin
OICMKCED_00771 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
OICMKCED_00772 4.1e-107 yvgT S membrane
OICMKCED_00773 0.0 helD 3.6.4.12 L DNA helicase
OICMKCED_00774 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OICMKCED_00775 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
OICMKCED_00776 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
OICMKCED_00777 5.4e-86 yvgO
OICMKCED_00778 1.1e-155 yvgN S reductase
OICMKCED_00779 6.9e-119 modB P COG4149 ABC-type molybdate transport system, permease component
OICMKCED_00780 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
OICMKCED_00781 9.2e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
OICMKCED_00782 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OICMKCED_00783 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
OICMKCED_00784 6.5e-16 S Small spore protein J (Spore_SspJ)
OICMKCED_00785 4.9e-236 yvsH E Arginine ornithine antiporter
OICMKCED_00786 4.5e-177 fhuD P ABC transporter
OICMKCED_00787 7.9e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OICMKCED_00788 6.9e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OICMKCED_00789 4.9e-148 fhuC 3.6.3.34 HP ABC transporter
OICMKCED_00790 7.6e-174 M Efflux transporter rnd family, mfp subunit
OICMKCED_00791 1.6e-123 macB V ABC transporter, ATP-binding protein
OICMKCED_00792 4.1e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
OICMKCED_00793 1.1e-63 yvrL S Regulatory protein YrvL
OICMKCED_00794 3.1e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
OICMKCED_00795 2.4e-19 S YvrJ protein family
OICMKCED_00796 1.6e-97 yvrI K RNA polymerase
OICMKCED_00797 3.6e-22
OICMKCED_00798 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OICMKCED_00799 0.0 T PhoQ Sensor
OICMKCED_00800 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
OICMKCED_00801 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OICMKCED_00802 1.3e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
OICMKCED_00803 2.5e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OICMKCED_00804 5.2e-248 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
OICMKCED_00805 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
OICMKCED_00806 4.8e-227 yvqJ EGP Major facilitator Superfamily
OICMKCED_00807 5.6e-62 liaI S membrane
OICMKCED_00808 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
OICMKCED_00809 1.3e-125 liaG S Putative adhesin
OICMKCED_00810 4.7e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
OICMKCED_00811 5.5e-187 vraS 2.7.13.3 T Histidine kinase
OICMKCED_00812 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OICMKCED_00813 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
OICMKCED_00814 9.1e-198 gerAB E Spore germination protein
OICMKCED_00815 3.7e-247 gerAA EG Spore germination protein
OICMKCED_00816 1.1e-23 S Protein of unknown function (DUF3970)
OICMKCED_00817 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OICMKCED_00818 4.3e-158 yuxN K Transcriptional regulator
OICMKCED_00819 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
OICMKCED_00820 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OICMKCED_00821 3.1e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OICMKCED_00822 1.2e-79 dps P Ferritin-like domain
OICMKCED_00823 8.9e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OICMKCED_00824 9.4e-301 pepF2 E COG1164 Oligoendopeptidase F
OICMKCED_00825 2.5e-66 S YusW-like protein
OICMKCED_00826 3.9e-153 yusV 3.6.3.34 HP ABC transporter
OICMKCED_00827 3.8e-47 yusU S Protein of unknown function (DUF2573)
OICMKCED_00828 5.7e-158 yusT K LysR substrate binding domain
OICMKCED_00829 5e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OICMKCED_00830 6e-64 yusQ S Tautomerase enzyme
OICMKCED_00831 8.5e-293 yusP P Major facilitator superfamily
OICMKCED_00832 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
OICMKCED_00833 2.1e-52 yusN M Coat F domain
OICMKCED_00834 5.1e-40
OICMKCED_00835 7.1e-164 fadM E Proline dehydrogenase
OICMKCED_00836 8.1e-09 S YuzL-like protein
OICMKCED_00837 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
OICMKCED_00838 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
OICMKCED_00839 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
OICMKCED_00840 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
OICMKCED_00841 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
OICMKCED_00842 1.1e-39 yusG S Protein of unknown function (DUF2553)
OICMKCED_00843 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
OICMKCED_00844 9.5e-55 traF CO Thioredoxin
OICMKCED_00845 3.2e-56 yusD S SCP-2 sterol transfer family
OICMKCED_00846 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OICMKCED_00847 3e-95 metI P COG2011 ABC-type metal ion transport system, permease component
OICMKCED_00848 4.2e-147 metQ P Belongs to the NlpA lipoprotein family
OICMKCED_00849 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OICMKCED_00850 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
OICMKCED_00851 1.4e-245 sufD O assembly protein SufD
OICMKCED_00852 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OICMKCED_00853 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
OICMKCED_00854 1e-270 sufB O FeS cluster assembly
OICMKCED_00855 1e-41
OICMKCED_00857 1.4e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
OICMKCED_00858 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
OICMKCED_00859 8.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
OICMKCED_00860 1.2e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
OICMKCED_00861 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
OICMKCED_00862 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
OICMKCED_00863 2.4e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
OICMKCED_00864 1.2e-134 yurK K UTRA
OICMKCED_00865 5.9e-205 msmX P Belongs to the ABC transporter superfamily
OICMKCED_00866 5.2e-164 bsn L Ribonuclease
OICMKCED_00867 2.3e-237 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OICMKCED_00868 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
OICMKCED_00870 3.8e-187 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OICMKCED_00871 7.6e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
OICMKCED_00872 3.4e-144 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
OICMKCED_00873 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
OICMKCED_00874 5.3e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
OICMKCED_00875 2.1e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
OICMKCED_00876 1.1e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
OICMKCED_00877 9.6e-223 pbuX F xanthine
OICMKCED_00878 1.4e-235 pbuX F Permease family
OICMKCED_00879 6.4e-301 pucR QT COG2508 Regulator of polyketide synthase expression
OICMKCED_00880 4.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
OICMKCED_00881 2.8e-60 yunG
OICMKCED_00882 4.3e-171 yunF S Protein of unknown function DUF72
OICMKCED_00883 2e-141 yunE S membrane transporter protein
OICMKCED_00884 5.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OICMKCED_00885 3.1e-47 yunC S Domain of unknown function (DUF1805)
OICMKCED_00886 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
OICMKCED_00887 4.5e-196 lytH M Peptidase, M23
OICMKCED_00888 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OICMKCED_00889 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OICMKCED_00890 9.7e-48 yutD S protein conserved in bacteria
OICMKCED_00891 1e-75 yutE S Protein of unknown function DUF86
OICMKCED_00892 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OICMKCED_00893 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OICMKCED_00894 5e-198 yutH S Spore coat protein
OICMKCED_00895 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
OICMKCED_00896 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OICMKCED_00897 1.9e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OICMKCED_00898 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
OICMKCED_00899 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
OICMKCED_00900 3.5e-57 yuzD S protein conserved in bacteria
OICMKCED_00901 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
OICMKCED_00902 3.2e-39 yuzB S Belongs to the UPF0349 family
OICMKCED_00903 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OICMKCED_00904 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OICMKCED_00905 3.7e-63 erpA S Belongs to the HesB IscA family
OICMKCED_00906 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OICMKCED_00907 7.2e-115 paiB K Putative FMN-binding domain
OICMKCED_00908 7.9e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OICMKCED_00910 1.7e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
OICMKCED_00911 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
OICMKCED_00912 3.2e-26 yuiB S Putative membrane protein
OICMKCED_00913 1.8e-116 yuiC S protein conserved in bacteria
OICMKCED_00914 1.2e-77 yuiD S protein conserved in bacteria
OICMKCED_00915 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OICMKCED_00916 3.9e-211 yuiF S antiporter
OICMKCED_00917 2.6e-93 bioY S Biotin biosynthesis protein
OICMKCED_00918 4.9e-121 yuiH S Oxidoreductase molybdopterin binding domain
OICMKCED_00919 9.6e-166 besA S Putative esterase
OICMKCED_00920 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OICMKCED_00921 1.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
OICMKCED_00922 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
OICMKCED_00923 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
OICMKCED_00924 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OICMKCED_00925 5e-36 mbtH S MbtH-like protein
OICMKCED_00926 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
OICMKCED_00927 1.8e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
OICMKCED_00928 6.5e-229 yukF QT Transcriptional regulator
OICMKCED_00929 2.8e-45 esxA S Belongs to the WXG100 family
OICMKCED_00930 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
OICMKCED_00931 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
OICMKCED_00932 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
OICMKCED_00933 0.0 esaA S type VII secretion protein EsaA
OICMKCED_00934 7.3e-64 yueC S Family of unknown function (DUF5383)
OICMKCED_00935 1.7e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OICMKCED_00936 4.1e-95 yueE S phosphohydrolase
OICMKCED_00937 2.9e-24 S Protein of unknown function (DUF2642)
OICMKCED_00938 5.2e-71 S Protein of unknown function (DUF2283)
OICMKCED_00939 2.7e-189 yueF S transporter activity
OICMKCED_00940 6.6e-31 yueG S Spore germination protein gerPA/gerPF
OICMKCED_00941 7.4e-39 yueH S YueH-like protein
OICMKCED_00942 1.5e-65 yueI S Protein of unknown function (DUF1694)
OICMKCED_00943 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
OICMKCED_00944 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OICMKCED_00945 1.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
OICMKCED_00946 1.1e-22 yuzC
OICMKCED_00948 2.9e-128 comQ H Belongs to the FPP GGPP synthase family
OICMKCED_00950 0.0 comP 2.7.13.3 T Histidine kinase
OICMKCED_00951 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OICMKCED_00952 5.1e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
OICMKCED_00953 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
OICMKCED_00954 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OICMKCED_00955 2.4e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OICMKCED_00956 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OICMKCED_00957 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OICMKCED_00958 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OICMKCED_00959 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OICMKCED_00960 1e-15
OICMKCED_00961 1.3e-233 maeN C COG3493 Na citrate symporter
OICMKCED_00962 3.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
OICMKCED_00963 3.2e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
OICMKCED_00964 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
OICMKCED_00965 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
OICMKCED_00966 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
OICMKCED_00967 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OICMKCED_00968 6.3e-78 yufK S Family of unknown function (DUF5366)
OICMKCED_00969 6.3e-75 yuxK S protein conserved in bacteria
OICMKCED_00970 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
OICMKCED_00971 3.8e-185 yuxJ EGP Major facilitator Superfamily
OICMKCED_00973 1.9e-115 kapD L the KinA pathway to sporulation
OICMKCED_00974 2.4e-68 kapB G Kinase associated protein B
OICMKCED_00975 4.6e-233 T PhoQ Sensor
OICMKCED_00976 1.3e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
OICMKCED_00977 4.6e-39 yugE S Domain of unknown function (DUF1871)
OICMKCED_00978 2.5e-155 yugF I Hydrolase
OICMKCED_00979 1.6e-85 alaR K Transcriptional regulator
OICMKCED_00980 2.1e-199 yugH 2.6.1.1 E Aminotransferase
OICMKCED_00981 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
OICMKCED_00982 1.1e-34 yuzA S Domain of unknown function (DUF378)
OICMKCED_00983 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
OICMKCED_00984 2.6e-227 yugK C Dehydrogenase
OICMKCED_00985 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
OICMKCED_00987 1.4e-71 yugN S YugN-like family
OICMKCED_00988 8.2e-182 yugO P COG1226 Kef-type K transport systems
OICMKCED_00989 1.1e-53 mstX S Membrane-integrating protein Mistic
OICMKCED_00990 2.3e-38
OICMKCED_00991 1.4e-116 yugP S Zn-dependent protease
OICMKCED_00992 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
OICMKCED_00993 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
OICMKCED_00994 2.1e-72 yugU S Uncharacterised protein family UPF0047
OICMKCED_00995 2.3e-35
OICMKCED_00996 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
OICMKCED_00997 9.3e-225 mcpA NT chemotaxis protein
OICMKCED_00998 9.9e-219 mcpA NT chemotaxis protein
OICMKCED_00999 8.5e-295 mcpA NT chemotaxis protein
OICMKCED_01000 7.3e-238 mcpA NT chemotaxis protein
OICMKCED_01001 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
OICMKCED_01002 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
OICMKCED_01003 1.4e-275 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
OICMKCED_01004 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
OICMKCED_01005 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
OICMKCED_01006 3.3e-183 ygjR S Oxidoreductase
OICMKCED_01007 3.1e-196 yubA S transporter activity
OICMKCED_01008 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
OICMKCED_01010 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
OICMKCED_01011 1.7e-274 yubD P Major Facilitator Superfamily
OICMKCED_01012 7.9e-151 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OICMKCED_01013 1e-38 yiaA S yiaA/B two helix domain
OICMKCED_01014 7.9e-236 ktrB P Potassium
OICMKCED_01015 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
OICMKCED_01016 2.2e-91 yuaB
OICMKCED_01017 6.7e-93 yuaC K Belongs to the GbsR family
OICMKCED_01018 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
OICMKCED_01019 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
OICMKCED_01020 2.3e-107 yuaD
OICMKCED_01021 1.1e-83 yuaE S DinB superfamily
OICMKCED_01022 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
OICMKCED_01023 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
OICMKCED_01024 2.4e-92 M1-753 M FR47-like protein
OICMKCED_01025 1.3e-89 thiT S Thiamine transporter protein (Thia_YuaJ)
OICMKCED_01037 1.3e-09
OICMKCED_01046 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OICMKCED_01047 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OICMKCED_01048 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
OICMKCED_01049 7.6e-285 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
OICMKCED_01050 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
OICMKCED_01051 9.9e-77 tspO T membrane
OICMKCED_01052 4.8e-204 cotI S Spore coat protein
OICMKCED_01053 1.8e-217 cotSA M Glycosyl transferases group 1
OICMKCED_01054 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
OICMKCED_01056 3e-234 ytcC M Glycosyltransferase Family 4
OICMKCED_01057 3.1e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
OICMKCED_01058 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OICMKCED_01059 3.6e-151 galU 2.7.7.9 M Nucleotidyl transferase
OICMKCED_01060 4.4e-132 dksA T COG1734 DnaK suppressor protein
OICMKCED_01061 4.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
OICMKCED_01062 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OICMKCED_01063 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
OICMKCED_01064 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OICMKCED_01065 1.8e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
OICMKCED_01066 4.6e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
OICMKCED_01067 2e-169 troA P Belongs to the bacterial solute-binding protein 9 family
OICMKCED_01068 1.2e-135 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OICMKCED_01069 1.1e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OICMKCED_01070 2.8e-149 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
OICMKCED_01071 1.1e-24 S Domain of Unknown Function (DUF1540)
OICMKCED_01072 1.2e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
OICMKCED_01073 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
OICMKCED_01074 3.6e-41 rpmE2 J Ribosomal protein L31
OICMKCED_01075 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OICMKCED_01076 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OICMKCED_01077 1.1e-72 ytkA S YtkA-like
OICMKCED_01079 2.1e-76 dps P Belongs to the Dps family
OICMKCED_01080 3.5e-62 ytkC S Bacteriophage holin family
OICMKCED_01081 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
OICMKCED_01082 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OICMKCED_01083 1.4e-144 ytlC P ABC transporter
OICMKCED_01084 2.8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OICMKCED_01085 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
OICMKCED_01086 1.2e-38 ytmB S Protein of unknown function (DUF2584)
OICMKCED_01087 9.7e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OICMKCED_01088 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OICMKCED_01089 0.0 asnB 6.3.5.4 E Asparagine synthase
OICMKCED_01090 1.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
OICMKCED_01091 2.1e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OICMKCED_01092 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
OICMKCED_01093 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
OICMKCED_01094 2.4e-104 ytqB J Putative rRNA methylase
OICMKCED_01095 8.1e-190 yhcC S Fe-S oxidoreductase
OICMKCED_01096 6.7e-41 ytzC S Protein of unknown function (DUF2524)
OICMKCED_01098 5.1e-66 ytrA K GntR family transcriptional regulator
OICMKCED_01099 4.2e-161 ytrB P abc transporter atp-binding protein
OICMKCED_01100 2.1e-153 P ABC-2 family transporter protein
OICMKCED_01101 7e-149
OICMKCED_01102 9.1e-127 ytrE V ABC transporter, ATP-binding protein
OICMKCED_01103 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
OICMKCED_01104 3.4e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OICMKCED_01105 1.6e-185 T PhoQ Sensor
OICMKCED_01106 1.1e-138 bceA V ABC transporter, ATP-binding protein
OICMKCED_01107 0.0 bceB V ABC transporter (permease)
OICMKCED_01108 4.3e-42 yttA 2.7.13.3 S Pfam Transposase IS66
OICMKCED_01109 6.6e-210 yttB EGP Major facilitator Superfamily
OICMKCED_01110 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
OICMKCED_01111 7.7e-55 ytvB S Protein of unknown function (DUF4257)
OICMKCED_01112 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OICMKCED_01113 8.1e-51 ytwF P Sulfurtransferase
OICMKCED_01114 1.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
OICMKCED_01115 4.4e-144 amyC P ABC transporter (permease)
OICMKCED_01116 6.2e-168 amyD P ABC transporter
OICMKCED_01117 1.4e-245 msmE G Bacterial extracellular solute-binding protein
OICMKCED_01118 1.2e-188 msmR K Transcriptional regulator
OICMKCED_01119 1.9e-172 ytaP S Acetyl xylan esterase (AXE1)
OICMKCED_01120 5.2e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
OICMKCED_01121 5.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
OICMKCED_01122 3.9e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OICMKCED_01123 1.7e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OICMKCED_01124 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OICMKCED_01125 1.3e-221 bioI 1.14.14.46 C Cytochrome P450
OICMKCED_01126 2.8e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
OICMKCED_01127 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
OICMKCED_01128 1.5e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
OICMKCED_01129 0.0 ytdP K Transcriptional regulator
OICMKCED_01130 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
OICMKCED_01131 9.5e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
OICMKCED_01132 7.3e-71 yteS G transport
OICMKCED_01133 1.1e-255 yteT S Oxidoreductase family, C-terminal alpha/beta domain
OICMKCED_01134 4.5e-115 yteU S Integral membrane protein
OICMKCED_01135 3.1e-26 yteV S Sporulation protein Cse60
OICMKCED_01136 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
OICMKCED_01137 3.1e-231 ytfP S HI0933-like protein
OICMKCED_01138 4.7e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OICMKCED_01139 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OICMKCED_01140 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
OICMKCED_01141 4e-130 ythP V ABC transporter
OICMKCED_01142 2.5e-198 ythQ U Bacterial ABC transporter protein EcsB
OICMKCED_01143 7.2e-226 pbuO S permease
OICMKCED_01144 1.9e-269 pepV 3.5.1.18 E Dipeptidase
OICMKCED_01145 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OICMKCED_01146 2.1e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OICMKCED_01147 1.3e-165 ytlQ
OICMKCED_01148 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
OICMKCED_01149 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
OICMKCED_01150 2.3e-150 ytmP 2.7.1.89 M Phosphotransferase
OICMKCED_01151 2e-45 ytzH S YtzH-like protein
OICMKCED_01152 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OICMKCED_01153 2.7e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
OICMKCED_01154 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
OICMKCED_01155 9.8e-52 ytzB S small secreted protein
OICMKCED_01156 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
OICMKCED_01157 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
OICMKCED_01158 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OICMKCED_01159 9.8e-149 ytpQ S Belongs to the UPF0354 family
OICMKCED_01160 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OICMKCED_01161 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
OICMKCED_01162 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
OICMKCED_01163 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OICMKCED_01164 6.6e-17 ytxH S COG4980 Gas vesicle protein
OICMKCED_01165 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
OICMKCED_01166 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
OICMKCED_01167 1.7e-182 ccpA K catabolite control protein A
OICMKCED_01168 2.1e-146 motA N flagellar motor
OICMKCED_01169 1.4e-125 motS N Flagellar motor protein
OICMKCED_01170 3.5e-224 acuC BQ histone deacetylase
OICMKCED_01171 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
OICMKCED_01172 1.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
OICMKCED_01173 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OICMKCED_01174 4.4e-236 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OICMKCED_01176 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OICMKCED_01177 1e-307 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
OICMKCED_01178 5.9e-88 ytsP 1.8.4.14 T GAF domain-containing protein
OICMKCED_01179 1e-108 yttP K Transcriptional regulator
OICMKCED_01180 2.3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
OICMKCED_01181 9.2e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OICMKCED_01182 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
OICMKCED_01183 3.1e-209 iscS2 2.8.1.7 E Cysteine desulfurase
OICMKCED_01184 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OICMKCED_01185 2e-29 sspB S spore protein
OICMKCED_01186 1e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OICMKCED_01187 4.4e-311 ytcJ S amidohydrolase
OICMKCED_01188 2.4e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OICMKCED_01189 5.1e-179 sppA OU signal peptide peptidase SppA
OICMKCED_01190 8.5e-87 yteJ S RDD family
OICMKCED_01191 1.6e-115 ytfI S Protein of unknown function (DUF2953)
OICMKCED_01192 8.7e-70 ytfJ S Sporulation protein YtfJ
OICMKCED_01193 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OICMKCED_01194 7e-165 ytxK 2.1.1.72 L DNA methylase
OICMKCED_01195 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OICMKCED_01196 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
OICMKCED_01197 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
OICMKCED_01198 3.4e-266 argH 4.3.2.1 E argininosuccinate lyase
OICMKCED_01200 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OICMKCED_01201 2.3e-130 ytkL S Belongs to the UPF0173 family
OICMKCED_01202 3.8e-173 ytlI K LysR substrate binding domain
OICMKCED_01203 1.4e-98 ytmI K Acetyltransferase (GNAT) domain
OICMKCED_01204 8.9e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
OICMKCED_01205 2.9e-148 tcyK M Bacterial periplasmic substrate-binding proteins
OICMKCED_01206 9.1e-122 tcyL P Binding-protein-dependent transport system inner membrane component
OICMKCED_01207 1.6e-118 tcyM U Binding-protein-dependent transport system inner membrane component
OICMKCED_01208 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OICMKCED_01209 4e-184 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OICMKCED_01210 7.1e-46 ytnI O COG0695 Glutaredoxin and related proteins
OICMKCED_01211 2.6e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OICMKCED_01212 1.2e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
OICMKCED_01213 5.1e-237 ytnL 3.5.1.47 E hydrolase activity
OICMKCED_01214 4.9e-157 ytnM S membrane transporter protein
OICMKCED_01215 8e-241 ytoI K transcriptional regulator containing CBS domains
OICMKCED_01216 2.4e-47 ytpI S YtpI-like protein
OICMKCED_01217 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
OICMKCED_01218 9.2e-29
OICMKCED_01219 1.2e-67 ytrI
OICMKCED_01220 3.2e-56 ytrH S Sporulation protein YtrH
OICMKCED_01221 0.0 dnaE 2.7.7.7 L DNA polymerase
OICMKCED_01222 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
OICMKCED_01223 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OICMKCED_01224 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
OICMKCED_01225 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OICMKCED_01226 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OICMKCED_01227 1.1e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
OICMKCED_01228 9.9e-192 ytvI S sporulation integral membrane protein YtvI
OICMKCED_01229 2.3e-70 yeaL S membrane
OICMKCED_01230 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
OICMKCED_01231 4.1e-242 icd 1.1.1.42 C isocitrate
OICMKCED_01232 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
OICMKCED_01233 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OICMKCED_01234 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
OICMKCED_01235 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OICMKCED_01236 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OICMKCED_01237 1.1e-107 ytaF P Probably functions as a manganese efflux pump
OICMKCED_01238 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OICMKCED_01239 8.9e-161 ytbE S reductase
OICMKCED_01240 2.5e-201 ytbD EGP Major facilitator Superfamily
OICMKCED_01241 9.9e-67 ytcD K Transcriptional regulator
OICMKCED_01242 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OICMKCED_01243 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OICMKCED_01244 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OICMKCED_01245 3.5e-266 dnaB L Membrane attachment protein
OICMKCED_01246 6.6e-173 dnaI L Primosomal protein DnaI
OICMKCED_01247 4.9e-111 ytxB S SNARE associated Golgi protein
OICMKCED_01248 7.1e-158 ytxC S YtxC-like family
OICMKCED_01250 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OICMKCED_01251 4.7e-148 ysaA S HAD-hyrolase-like
OICMKCED_01252 0.0 lytS 2.7.13.3 T Histidine kinase
OICMKCED_01253 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
OICMKCED_01254 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OICMKCED_01255 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OICMKCED_01257 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OICMKCED_01258 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
OICMKCED_01259 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OICMKCED_01260 7.5e-45 ysdA S Membrane
OICMKCED_01261 9.2e-68 ysdB S Sigma-w pathway protein YsdB
OICMKCED_01262 7.6e-205 ysdC G COG1363 Cellulase M and related proteins
OICMKCED_01263 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OICMKCED_01264 2.7e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
OICMKCED_01265 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
OICMKCED_01266 5.5e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
OICMKCED_01267 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
OICMKCED_01268 4.8e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
OICMKCED_01269 8.1e-254 araN G carbohydrate transport
OICMKCED_01270 2.7e-166 araP G carbohydrate transport
OICMKCED_01271 4.9e-143 araQ G transport system permease
OICMKCED_01272 5.1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
OICMKCED_01273 0.0 cstA T Carbon starvation protein
OICMKCED_01274 1.7e-41 ysfE 4.4.1.5 E Glyoxalase-like domain
OICMKCED_01275 2.6e-255 glcF C Glycolate oxidase
OICMKCED_01276 6.7e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
OICMKCED_01277 1e-204 ysfB KT regulator
OICMKCED_01278 2.6e-32 sspI S Belongs to the SspI family
OICMKCED_01279 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OICMKCED_01280 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OICMKCED_01281 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OICMKCED_01282 5.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OICMKCED_01283 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OICMKCED_01284 1.3e-85 cvpA S membrane protein, required for colicin V production
OICMKCED_01285 0.0 polX L COG1796 DNA polymerase IV (family X)
OICMKCED_01286 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OICMKCED_01287 7.3e-68 yshE S membrane
OICMKCED_01288 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OICMKCED_01289 2.7e-100 fadR K Transcriptional regulator
OICMKCED_01290 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OICMKCED_01291 4.5e-135 etfB C Electron transfer flavoprotein
OICMKCED_01292 4.2e-178 etfA C Electron transfer flavoprotein
OICMKCED_01294 8.9e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
OICMKCED_01295 2e-52 trxA O Belongs to the thioredoxin family
OICMKCED_01296 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OICMKCED_01297 5.4e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OICMKCED_01298 2.7e-79 yslB S Protein of unknown function (DUF2507)
OICMKCED_01299 2.4e-107 sdhC C succinate dehydrogenase
OICMKCED_01300 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OICMKCED_01301 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OICMKCED_01302 1.6e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
OICMKCED_01303 1.2e-17 gerE K Transcriptional regulator
OICMKCED_01304 4.4e-48 yqaB E IrrE N-terminal-like domain
OICMKCED_01306 3.7e-24 K sequence-specific DNA binding
OICMKCED_01307 8.1e-14 K Helix-turn-helix XRE-family like proteins
OICMKCED_01309 5e-24
OICMKCED_01310 1.2e-44 S DNA binding
OICMKCED_01311 1.9e-82
OICMKCED_01317 4.5e-153 yqaJ L YqaJ-like viral recombinase domain
OICMKCED_01318 5.7e-115 recT L RecT family
OICMKCED_01319 2.1e-38 3.1.3.16 L DnaD domain protein
OICMKCED_01320 5.5e-120 xkdC L IstB-like ATP binding protein
OICMKCED_01322 3.8e-10 S YopX protein
OICMKCED_01323 1.3e-52 S Protein of unknown function (DUF1064)
OICMKCED_01325 8.3e-20 yqaO S Phage-like element PBSX protein XtrA
OICMKCED_01327 2.1e-75
OICMKCED_01334 1.5e-70 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OICMKCED_01336 8.9e-17 K Transcriptional regulator
OICMKCED_01338 2.7e-78 yqaS L DNA packaging
OICMKCED_01339 4.1e-162 S Terminase RNAseH like domain
OICMKCED_01340 6.3e-159 S Phage portal protein, SPP1 Gp6-like
OICMKCED_01342 6.8e-67 S Domain of unknown function (DUF4355)
OICMKCED_01343 1.9e-111 S Phage capsid family
OICMKCED_01345 9e-31 S Phage Mu protein F like protein
OICMKCED_01346 2.4e-16 S Phage gp6-like head-tail connector protein
OICMKCED_01347 3.6e-48
OICMKCED_01348 1.2e-22
OICMKCED_01349 7e-30
OICMKCED_01350 7.2e-104 Z012_02110 S Protein of unknown function (DUF3383)
OICMKCED_01351 3e-34
OICMKCED_01352 3.6e-16
OICMKCED_01353 8.2e-139 N phage tail tape measure protein
OICMKCED_01354 3e-40 3.5.1.28 M LysM domain
OICMKCED_01355 4.1e-30
OICMKCED_01356 4.7e-89
OICMKCED_01357 4.7e-23
OICMKCED_01358 4.8e-23 S Protein of unknown function (DUF2634)
OICMKCED_01359 3e-106 Z012_12235 S homolog of phage Mu protein gp47
OICMKCED_01360 1.3e-60
OICMKCED_01361 1.7e-35
OICMKCED_01363 1e-14 xkdX
OICMKCED_01364 1.1e-27 xhlA S Haemolysin XhlA
OICMKCED_01365 2.7e-31 xhlB S SPP1 phage holin
OICMKCED_01366 4.4e-104 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OICMKCED_01367 7e-141 V Abi-like protein
OICMKCED_01368 3.9e-43 S YolD-like protein
OICMKCED_01369 4e-167 L Recombinase
OICMKCED_01370 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
OICMKCED_01371 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OICMKCED_01372 2.9e-196 gerM S COG5401 Spore germination protein
OICMKCED_01373 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OICMKCED_01374 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OICMKCED_01375 1.4e-92 ysnB S Phosphoesterase
OICMKCED_01377 9.1e-134 ysnF S protein conserved in bacteria
OICMKCED_01378 7.6e-82 ysnE K acetyltransferase
OICMKCED_01380 0.0 ilvB 2.2.1.6 E Acetolactate synthase
OICMKCED_01381 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
OICMKCED_01382 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OICMKCED_01383 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OICMKCED_01384 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
OICMKCED_01385 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OICMKCED_01386 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OICMKCED_01387 2.3e-187 ysoA H Tetratricopeptide repeat
OICMKCED_01388 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OICMKCED_01389 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OICMKCED_01390 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
OICMKCED_01391 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OICMKCED_01392 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
OICMKCED_01393 7e-89 ysxD
OICMKCED_01394 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OICMKCED_01395 3.6e-146 hemX O cytochrome C
OICMKCED_01396 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
OICMKCED_01397 7.9e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OICMKCED_01398 6.2e-182 hemB 4.2.1.24 H Belongs to the ALAD family
OICMKCED_01399 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OICMKCED_01400 2.3e-216 spoVID M stage VI sporulation protein D
OICMKCED_01401 9.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OICMKCED_01402 1.6e-25
OICMKCED_01403 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OICMKCED_01404 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OICMKCED_01405 3.3e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
OICMKCED_01406 2.8e-161 spoIIB S Sporulation related domain
OICMKCED_01407 1.8e-101 maf D septum formation protein Maf
OICMKCED_01408 1.3e-125 radC E Belongs to the UPF0758 family
OICMKCED_01409 1.8e-184 mreB D Rod shape-determining protein MreB
OICMKCED_01410 2.8e-157 mreC M Involved in formation and maintenance of cell shape
OICMKCED_01411 1.4e-84 mreD M shape-determining protein
OICMKCED_01412 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
OICMKCED_01413 4.7e-143 minD D Belongs to the ParA family
OICMKCED_01414 1.1e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
OICMKCED_01415 2.7e-160 spoIVFB S Stage IV sporulation protein
OICMKCED_01416 1.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
OICMKCED_01417 4.1e-56 ysxB J ribosomal protein
OICMKCED_01418 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OICMKCED_01419 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
OICMKCED_01420 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OICMKCED_01421 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
OICMKCED_01422 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
OICMKCED_01423 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
OICMKCED_01424 5e-218 nifS 2.8.1.7 E Cysteine desulfurase
OICMKCED_01425 7.3e-305 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
OICMKCED_01426 7.3e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
OICMKCED_01427 1.8e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OICMKCED_01428 9.8e-158 safA M spore coat assembly protein SafA
OICMKCED_01429 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OICMKCED_01430 1.6e-126 yebC K transcriptional regulatory protein
OICMKCED_01431 3.4e-261 alsT E Sodium alanine symporter
OICMKCED_01433 3.1e-51 S Family of unknown function (DUF5412)
OICMKCED_01435 1.9e-118 yrzF T serine threonine protein kinase
OICMKCED_01436 1.4e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
OICMKCED_01437 5.3e-253 csbX EGP Major facilitator Superfamily
OICMKCED_01438 4.8e-93 bofC S BofC C-terminal domain
OICMKCED_01439 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OICMKCED_01440 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OICMKCED_01441 1e-17 yrzS S Protein of unknown function (DUF2905)
OICMKCED_01442 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OICMKCED_01443 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OICMKCED_01444 1.1e-38 yajC U Preprotein translocase subunit YajC
OICMKCED_01445 2.2e-73 yrzE S Protein of unknown function (DUF3792)
OICMKCED_01446 1.7e-111 yrbG S membrane
OICMKCED_01447 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OICMKCED_01448 1.6e-48 yrzD S Post-transcriptional regulator
OICMKCED_01449 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OICMKCED_01450 1.1e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
OICMKCED_01451 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
OICMKCED_01452 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OICMKCED_01453 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OICMKCED_01454 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OICMKCED_01455 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OICMKCED_01456 7e-260 lytH 3.5.1.28 M COG3103 SH3 domain protein
OICMKCED_01458 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
OICMKCED_01459 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OICMKCED_01460 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
OICMKCED_01461 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
OICMKCED_01462 1.2e-70 cymR K Transcriptional regulator
OICMKCED_01463 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
OICMKCED_01464 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OICMKCED_01465 1.4e-15 S COG0457 FOG TPR repeat
OICMKCED_01466 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OICMKCED_01467 3.5e-82 yrrD S protein conserved in bacteria
OICMKCED_01468 9.8e-31 yrzR
OICMKCED_01469 8e-08 S Protein of unknown function (DUF3918)
OICMKCED_01470 7.6e-107 glnP P ABC transporter
OICMKCED_01471 1.8e-108 gluC P ABC transporter
OICMKCED_01472 9.7e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
OICMKCED_01473 5.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OICMKCED_01474 6e-162 yrrI S AI-2E family transporter
OICMKCED_01475 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OICMKCED_01476 1.7e-41 yrzL S Belongs to the UPF0297 family
OICMKCED_01477 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OICMKCED_01478 1.2e-45 yrzB S Belongs to the UPF0473 family
OICMKCED_01479 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OICMKCED_01480 5e-119 yrrM 2.1.1.104 S O-methyltransferase
OICMKCED_01481 7.8e-174 yegQ O Peptidase U32
OICMKCED_01482 2.7e-246 yegQ O COG0826 Collagenase and related proteases
OICMKCED_01483 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
OICMKCED_01484 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OICMKCED_01485 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
OICMKCED_01486 2.5e-60 yrrS S Protein of unknown function (DUF1510)
OICMKCED_01487 1e-25 yrzA S Protein of unknown function (DUF2536)
OICMKCED_01488 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
OICMKCED_01489 2.7e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OICMKCED_01490 6.1e-25 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
OICMKCED_01491 1.3e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OICMKCED_01492 4.6e-35 yrhC S YrhC-like protein
OICMKCED_01493 5.4e-78 yrhD S Protein of unknown function (DUF1641)
OICMKCED_01494 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
OICMKCED_01495 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
OICMKCED_01497 1.8e-142 focA P Formate nitrite
OICMKCED_01500 4.5e-97 yrhH Q methyltransferase
OICMKCED_01501 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
OICMKCED_01502 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OICMKCED_01503 4.3e-46 yrhK S YrhK-like protein
OICMKCED_01504 0.0 yrhL I Acyltransferase family
OICMKCED_01505 3.8e-151 rsiV S Protein of unknown function (DUF3298)
OICMKCED_01506 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
OICMKCED_01507 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
OICMKCED_01508 1.1e-105 yrhP E LysE type translocator
OICMKCED_01509 4.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
OICMKCED_01510 0.0 levR K PTS system fructose IIA component
OICMKCED_01511 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
OICMKCED_01512 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
OICMKCED_01513 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
OICMKCED_01514 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
OICMKCED_01515 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
OICMKCED_01516 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
OICMKCED_01517 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
OICMKCED_01518 1.6e-28 yphJ 4.1.1.44 S peroxiredoxin activity
OICMKCED_01519 1.6e-46 yraB K helix_turn_helix, mercury resistance
OICMKCED_01520 1.1e-49 yraD M Spore coat protein
OICMKCED_01521 7.5e-26 yraE
OICMKCED_01522 3.8e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OICMKCED_01523 6.4e-63 yraF M Spore coat protein
OICMKCED_01524 1.5e-36 yraG
OICMKCED_01525 3.8e-66 E Glyoxalase-like domain
OICMKCED_01527 2.4e-61 T sh3 domain protein
OICMKCED_01528 1.7e-60 T sh3 domain protein
OICMKCED_01529 4.9e-148 S Alpha beta hydrolase
OICMKCED_01530 2.1e-39 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OICMKCED_01531 5.8e-149 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
OICMKCED_01532 6.5e-204 yraM S PrpF protein
OICMKCED_01533 3.7e-162 yraN K Transcriptional regulator
OICMKCED_01534 4e-224 yraO C Citrate transporter
OICMKCED_01535 3.8e-187 yrpG C Aldo/keto reductase family
OICMKCED_01536 1.2e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
OICMKCED_01537 1.3e-113 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
OICMKCED_01538 2.2e-47 yjbR S YjbR
OICMKCED_01539 7.2e-118 bmrR K helix_turn_helix, mercury resistance
OICMKCED_01540 5.6e-98 flr S Flavin reductase like domain
OICMKCED_01541 6.4e-135 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
OICMKCED_01542 7e-154 2.2.1.1 G Transketolase, pyrimidine binding domain
OICMKCED_01543 4.3e-114 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OICMKCED_01544 2.8e-209 rbtT P Major Facilitator Superfamily
OICMKCED_01546 1.5e-100 K helix_turn_helix gluconate operon transcriptional repressor
OICMKCED_01547 1.6e-123 yrpD S Domain of unknown function, YrpD
OICMKCED_01548 3e-27 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OICMKCED_01549 3.9e-96 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OICMKCED_01551 5.9e-82 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OICMKCED_01552 4.4e-55 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OICMKCED_01553 1.5e-163 aadK G Streptomycin adenylyltransferase
OICMKCED_01554 6.4e-90 yrdA S DinB family
OICMKCED_01555 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
OICMKCED_01556 1.1e-23 K Acetyltransferase (GNAT) family
OICMKCED_01557 5.6e-228 cypA C Cytochrome P450
OICMKCED_01558 1.2e-15 yrdF K ribonuclease inhibitor
OICMKCED_01559 6.3e-79 bkdR K helix_turn_helix ASNC type
OICMKCED_01560 2.8e-137 azlC E AzlC protein
OICMKCED_01561 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
OICMKCED_01562 3e-227 brnQ E Component of the transport system for branched-chain amino acids
OICMKCED_01563 5e-162 gltR K LysR substrate binding domain
OICMKCED_01564 1.7e-66 yodA S tautomerase
OICMKCED_01565 3.5e-145 czcD P COG1230 Co Zn Cd efflux system component
OICMKCED_01566 3.5e-199 trkA P Oxidoreductase
OICMKCED_01567 9.5e-158 yrdQ K Transcriptional regulator
OICMKCED_01568 7.8e-169 yrdR EG EamA-like transporter family
OICMKCED_01569 3.9e-16 S YrzO-like protein
OICMKCED_01570 2.3e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OICMKCED_01571 5.9e-82 bltD 2.3.1.57 K FR47-like protein
OICMKCED_01572 1.3e-210 blt EGP Major facilitator Superfamily
OICMKCED_01573 3.1e-150 bltR K helix_turn_helix, mercury resistance
OICMKCED_01574 1.4e-106 yrkC G Cupin domain
OICMKCED_01575 7.8e-39 yrkD S protein conserved in bacteria
OICMKCED_01576 2.8e-82 yrkE O DsrE/DsrF/DrsH-like family
OICMKCED_01577 4.6e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
OICMKCED_01578 1.3e-207 yrkH P Rhodanese Homology Domain
OICMKCED_01579 2.7e-35 yrkI O Belongs to the sulfur carrier protein TusA family
OICMKCED_01580 8.3e-113 yrkJ S membrane transporter protein
OICMKCED_01581 7e-166 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
OICMKCED_01582 1.8e-216 mepA V Multidrug transporter MatE
OICMKCED_01583 3.3e-113 tetR3 K Transcriptional regulator
OICMKCED_01584 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OICMKCED_01585 8.9e-95 yqaB E IrrE N-terminal-like domain
OICMKCED_01587 5.2e-98 adk 2.7.4.3 F adenylate kinase activity
OICMKCED_01588 1.7e-09 S Protein of unknown function (DUF4064)
OICMKCED_01589 1.1e-32 K sequence-specific DNA binding
OICMKCED_01590 9.1e-18 K Helix-turn-helix XRE-family like proteins
OICMKCED_01592 1.2e-103
OICMKCED_01596 4.9e-163 yqaJ L YqaJ-like viral recombinase domain
OICMKCED_01597 4.2e-150 recT L RecT family
OICMKCED_01598 6e-118 3.1.3.16 L DnaD domain protein
OICMKCED_01599 4.2e-166 xkdC L IstB-like ATP binding protein
OICMKCED_01601 9.7e-71 rusA L Endodeoxyribonuclease RusA
OICMKCED_01602 4.1e-30 yqaO S Phage-like element PBSX protein XtrA
OICMKCED_01605 1.3e-76 L Transposase
OICMKCED_01607 4.6e-31
OICMKCED_01608 4.3e-95 yqaS L DNA packaging
OICMKCED_01609 2.1e-246 S phage terminase, large subunit
OICMKCED_01610 1.1e-286 yqbA S portal protein
OICMKCED_01611 7e-143 S Phage Mu protein F like protein
OICMKCED_01612 6.4e-41
OICMKCED_01613 3.8e-115 yqbD 2.1.1.72 L Putative phage serine protease XkdF
OICMKCED_01614 4.6e-166 xkdG S Phage capsid family
OICMKCED_01615 5.1e-45 S YqbF, hypothetical protein domain
OICMKCED_01616 6e-67 S Protein of unknown function (DUF3199)
OICMKCED_01617 9.7e-64 yqbH S Domain of unknown function (DUF3599)
OICMKCED_01618 6.7e-87 S Bacteriophage HK97-gp10, putative tail-component
OICMKCED_01619 1.3e-75
OICMKCED_01620 2.7e-25
OICMKCED_01621 2.2e-252 xkdK S Phage tail sheath C-terminal domain
OICMKCED_01622 6.1e-76 xkdM S Phage tail tube protein
OICMKCED_01623 2.8e-68 S Phage XkdN-like tail assembly chaperone protein, TAC
OICMKCED_01624 0.0 xkdO L Transglycosylase SLT domain
OICMKCED_01625 9.9e-113 xkdP S Lysin motif
OICMKCED_01626 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
OICMKCED_01627 1.8e-38 xkdR S Protein of unknown function (DUF2577)
OICMKCED_01628 1.1e-69 xkdS S Protein of unknown function (DUF2634)
OICMKCED_01629 3.4e-186 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OICMKCED_01630 3.1e-96 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
OICMKCED_01631 2.4e-38
OICMKCED_01632 3.4e-221
OICMKCED_01633 4.1e-56 xkdW S XkdW protein
OICMKCED_01634 1.3e-23
OICMKCED_01635 4.8e-165 xepA
OICMKCED_01636 5.8e-68 S Bacteriophage holin family
OICMKCED_01637 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OICMKCED_01639 1.9e-59
OICMKCED_01641 2.1e-100 S Suppressor of fused protein (SUFU)
OICMKCED_01642 4.1e-46
OICMKCED_01643 7.2e-24 S SMI1-KNR4 cell-wall
OICMKCED_01644 1.9e-163 yobL S Bacterial EndoU nuclease
OICMKCED_01647 1.6e-96 S Tetratricopeptide repeat
OICMKCED_01648 4.8e-145 yqcI S YqcI/YcgG family
OICMKCED_01649 1.6e-54 arsR K ArsR family transcriptional regulator
OICMKCED_01650 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OICMKCED_01651 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
OICMKCED_01652 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
OICMKCED_01653 1.4e-281 cisA2 L Recombinase
OICMKCED_01654 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OICMKCED_01655 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
OICMKCED_01656 2.3e-133 yqeB
OICMKCED_01657 6.5e-170 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
OICMKCED_01658 1.8e-105 yqeD S SNARE associated Golgi protein
OICMKCED_01659 9.2e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OICMKCED_01660 1.2e-140 yqeF E GDSL-like Lipase/Acylhydrolase
OICMKCED_01662 5.3e-95 yqeG S hydrolase of the HAD superfamily
OICMKCED_01663 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
OICMKCED_01664 7.8e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OICMKCED_01665 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
OICMKCED_01666 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OICMKCED_01667 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
OICMKCED_01668 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OICMKCED_01669 6.5e-139 yqeM Q Methyltransferase
OICMKCED_01670 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OICMKCED_01671 3.6e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
OICMKCED_01672 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
OICMKCED_01673 0.0 comEC S Competence protein ComEC
OICMKCED_01674 4.1e-15 S YqzM-like protein
OICMKCED_01675 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
OICMKCED_01676 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
OICMKCED_01677 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OICMKCED_01678 6.9e-223 spoIIP M stage II sporulation protein P
OICMKCED_01679 7.2e-53 yqxA S Protein of unknown function (DUF3679)
OICMKCED_01680 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OICMKCED_01681 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
OICMKCED_01682 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OICMKCED_01683 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OICMKCED_01684 0.0 dnaK O Heat shock 70 kDa protein
OICMKCED_01685 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OICMKCED_01686 5.4e-175 prmA J Methylates ribosomal protein L11
OICMKCED_01687 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OICMKCED_01688 1.8e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
OICMKCED_01689 8.2e-158 yqeW P COG1283 Na phosphate symporter
OICMKCED_01690 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
OICMKCED_01691 2.5e-61 yqeY S Yqey-like protein
OICMKCED_01692 1e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
OICMKCED_01693 4.3e-122 yqfA S UPF0365 protein
OICMKCED_01694 2.4e-21 yqfB
OICMKCED_01695 2.7e-45 yqfC S sporulation protein YqfC
OICMKCED_01696 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
OICMKCED_01697 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
OICMKCED_01699 0.0 yqfF S membrane-associated HD superfamily hydrolase
OICMKCED_01700 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OICMKCED_01701 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
OICMKCED_01702 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
OICMKCED_01703 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OICMKCED_01704 8.4e-19 S YqzL-like protein
OICMKCED_01705 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
OICMKCED_01706 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
OICMKCED_01707 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
OICMKCED_01708 4.5e-112 ccpN K CBS domain
OICMKCED_01709 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OICMKCED_01710 1.1e-86 yaiI S Belongs to the UPF0178 family
OICMKCED_01711 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OICMKCED_01712 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OICMKCED_01713 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
OICMKCED_01714 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
OICMKCED_01715 5.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OICMKCED_01716 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OICMKCED_01717 1.6e-12 yqfQ S YqfQ-like protein
OICMKCED_01718 1.9e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OICMKCED_01719 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OICMKCED_01720 2.1e-36 yqfT S Protein of unknown function (DUF2624)
OICMKCED_01721 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OICMKCED_01722 4.2e-77 zur P Belongs to the Fur family
OICMKCED_01723 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
OICMKCED_01724 2.8e-61 yqfX S membrane
OICMKCED_01725 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OICMKCED_01726 8.9e-47 yqfZ M LysM domain
OICMKCED_01727 1.5e-130 yqgB S Protein of unknown function (DUF1189)
OICMKCED_01728 4e-73 yqgC S protein conserved in bacteria
OICMKCED_01729 1.8e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
OICMKCED_01730 4.3e-231 yqgE EGP Major facilitator superfamily
OICMKCED_01731 0.0 pbpA 3.4.16.4 M penicillin-binding protein
OICMKCED_01732 1.7e-149 pstS P Phosphate
OICMKCED_01733 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
OICMKCED_01734 4.4e-158 pstA P Phosphate transport system permease
OICMKCED_01735 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OICMKCED_01736 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OICMKCED_01737 7.3e-72 yqzC S YceG-like family
OICMKCED_01738 3.5e-50 yqzD
OICMKCED_01740 5.1e-201 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
OICMKCED_01741 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OICMKCED_01742 5.1e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OICMKCED_01743 2.5e-09 yqgO
OICMKCED_01744 2.8e-261 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
OICMKCED_01745 3.1e-33 yqgQ S Protein conserved in bacteria
OICMKCED_01746 3.4e-180 glcK 2.7.1.2 G Glucokinase
OICMKCED_01747 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OICMKCED_01748 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
OICMKCED_01749 7.4e-197 yqgU
OICMKCED_01750 6.9e-50 yqgV S Thiamine-binding protein
OICMKCED_01751 8.9e-23 yqgW S Protein of unknown function (DUF2759)
OICMKCED_01752 5.6e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
OICMKCED_01753 1.8e-37 yqgY S Protein of unknown function (DUF2626)
OICMKCED_01754 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
OICMKCED_01756 3.2e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OICMKCED_01757 3.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OICMKCED_01758 7.2e-175 corA P Mg2 transporter protein
OICMKCED_01760 1.1e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OICMKCED_01761 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
OICMKCED_01762 1.4e-47 comGC U Required for transformation and DNA binding
OICMKCED_01763 1.2e-68 gspH NU protein transport across the cell outer membrane
OICMKCED_01764 7.6e-58 comGE
OICMKCED_01765 3.9e-44 comGF U Putative Competence protein ComGF
OICMKCED_01766 2.6e-43 S ComG operon protein 7
OICMKCED_01767 3.1e-26 yqzE S YqzE-like protein
OICMKCED_01768 7.3e-54 yqzG S Protein of unknown function (DUF3889)
OICMKCED_01769 9e-112 yqxM
OICMKCED_01770 2.5e-58 sipW 3.4.21.89 U Signal peptidase
OICMKCED_01771 4.3e-141 tasA S Cell division protein FtsN
OICMKCED_01772 1e-54 sinR K transcriptional
OICMKCED_01773 1.2e-24 sinI S Anti-repressor SinI
OICMKCED_01774 3.2e-152 yqhG S Bacterial protein YqhG of unknown function
OICMKCED_01775 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OICMKCED_01776 5.3e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
OICMKCED_01777 4.9e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OICMKCED_01778 1.4e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OICMKCED_01779 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
OICMKCED_01780 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
OICMKCED_01781 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
OICMKCED_01782 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
OICMKCED_01783 2.2e-61 yqhP
OICMKCED_01784 6.8e-173 yqhQ S Protein of unknown function (DUF1385)
OICMKCED_01785 6.6e-93 yqhR S Conserved membrane protein YqhR
OICMKCED_01786 4.2e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
OICMKCED_01787 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OICMKCED_01788 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OICMKCED_01789 7.9e-37 yqhV S Protein of unknown function (DUF2619)
OICMKCED_01790 3e-170 spoIIIAA S stage III sporulation protein AA
OICMKCED_01791 3.2e-84 spoIIIAB S Stage III sporulation protein
OICMKCED_01792 7.6e-29 spoIIIAC S stage III sporulation protein AC
OICMKCED_01793 2.3e-58 spoIIIAD S Stage III sporulation protein AD
OICMKCED_01794 1.3e-197 spoIIIAE S stage III sporulation protein AE
OICMKCED_01795 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
OICMKCED_01796 5e-109 spoIIIAG S stage III sporulation protein AG
OICMKCED_01797 3.1e-84 spoIIIAH S SpoIIIAH-like protein
OICMKCED_01798 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OICMKCED_01799 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
OICMKCED_01800 2.1e-67 yqhY S protein conserved in bacteria
OICMKCED_01801 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OICMKCED_01802 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OICMKCED_01803 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OICMKCED_01804 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OICMKCED_01805 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OICMKCED_01806 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OICMKCED_01807 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
OICMKCED_01808 1.7e-78 argR K Regulates arginine biosynthesis genes
OICMKCED_01809 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
OICMKCED_01810 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
OICMKCED_01811 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
OICMKCED_01813 2.8e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
OICMKCED_01814 5.9e-27
OICMKCED_01815 1.7e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
OICMKCED_01816 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OICMKCED_01817 2.6e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
OICMKCED_01818 1e-156 hbdA 1.1.1.157 I Dehydrogenase
OICMKCED_01819 6.7e-212 mmgC I acyl-CoA dehydrogenase
OICMKCED_01820 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
OICMKCED_01821 2.2e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
OICMKCED_01822 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OICMKCED_01823 4e-34 yqzF S Protein of unknown function (DUF2627)
OICMKCED_01824 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
OICMKCED_01825 3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
OICMKCED_01826 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
OICMKCED_01827 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
OICMKCED_01828 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OICMKCED_01829 7.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OICMKCED_01830 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OICMKCED_01831 4.4e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OICMKCED_01832 2.2e-151 bmrR K helix_turn_helix, mercury resistance
OICMKCED_01833 7.9e-208 norA EGP Major facilitator Superfamily
OICMKCED_01834 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OICMKCED_01835 9.3e-77 yqiW S Belongs to the UPF0403 family
OICMKCED_01836 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
OICMKCED_01837 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
OICMKCED_01838 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OICMKCED_01839 3.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
OICMKCED_01840 1.4e-98 yqjB S protein conserved in bacteria
OICMKCED_01842 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
OICMKCED_01843 1.8e-289 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OICMKCED_01844 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
OICMKCED_01845 8.9e-141 yqjF S Uncharacterized conserved protein (COG2071)
OICMKCED_01846 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OICMKCED_01847 4.5e-24 yqzJ
OICMKCED_01848 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OICMKCED_01849 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OICMKCED_01850 1.4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OICMKCED_01851 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OICMKCED_01852 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OICMKCED_01853 3.6e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OICMKCED_01854 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
OICMKCED_01855 0.0 rocB E arginine degradation protein
OICMKCED_01856 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OICMKCED_01857 1.8e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
OICMKCED_01858 5e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
OICMKCED_01859 7.9e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
OICMKCED_01860 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
OICMKCED_01861 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OICMKCED_01863 9e-226 yqjV G Major Facilitator Superfamily
OICMKCED_01865 1.6e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OICMKCED_01866 9.8e-50 S YolD-like protein
OICMKCED_01867 1.8e-86 yqjY K acetyltransferase
OICMKCED_01868 4e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
OICMKCED_01869 2e-194 yqkA K GrpB protein
OICMKCED_01870 2.8e-54 yqkB S Belongs to the HesB IscA family
OICMKCED_01871 9.4e-39 yqkC S Protein of unknown function (DUF2552)
OICMKCED_01872 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
OICMKCED_01873 3.1e-12 yqkE S Protein of unknown function (DUF3886)
OICMKCED_01874 6.3e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
OICMKCED_01876 2.6e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
OICMKCED_01877 3.1e-220 yqxK 3.6.4.12 L DNA helicase
OICMKCED_01878 4.5e-58 ansR K Transcriptional regulator
OICMKCED_01879 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
OICMKCED_01880 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
OICMKCED_01881 2.7e-234 mleN C Na H antiporter
OICMKCED_01882 5.5e-242 mleA 1.1.1.38 C malic enzyme
OICMKCED_01883 1.9e-30 yqkK
OICMKCED_01884 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
OICMKCED_01885 2.4e-80 fur P Belongs to the Fur family
OICMKCED_01886 1.4e-36 S Protein of unknown function (DUF4227)
OICMKCED_01887 2.6e-166 xerD L recombinase XerD
OICMKCED_01888 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
OICMKCED_01889 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OICMKCED_01890 6.3e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
OICMKCED_01891 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
OICMKCED_01892 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
OICMKCED_01893 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OICMKCED_01894 9.6e-112 spoVAA S Stage V sporulation protein AA
OICMKCED_01895 1e-67 spoVAB S Stage V sporulation protein AB
OICMKCED_01896 2.3e-78 spoVAC S stage V sporulation protein AC
OICMKCED_01897 9e-192 spoVAD I Stage V sporulation protein AD
OICMKCED_01898 2.2e-57 spoVAEB S stage V sporulation protein
OICMKCED_01899 1.4e-110 spoVAEA S stage V sporulation protein
OICMKCED_01900 1.4e-273 spoVAF EG Stage V sporulation protein AF
OICMKCED_01901 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OICMKCED_01902 8.1e-149 ypuA S Secreted protein
OICMKCED_01903 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OICMKCED_01908 5.9e-36 S Pfam Transposase IS66
OICMKCED_01909 1.9e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OICMKCED_01911 2.5e-32 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
OICMKCED_01912 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OICMKCED_01913 7.8e-55 ypuD
OICMKCED_01914 2.9e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OICMKCED_01915 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
OICMKCED_01916 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OICMKCED_01917 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
OICMKCED_01918 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OICMKCED_01919 4.2e-92 ypuF S Domain of unknown function (DUF309)
OICMKCED_01920 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OICMKCED_01921 2.4e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OICMKCED_01922 7.6e-97 ypuI S Protein of unknown function (DUF3907)
OICMKCED_01923 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
OICMKCED_01924 3.5e-103 spmA S Spore maturation protein
OICMKCED_01925 1.9e-87 spmB S Spore maturation protein
OICMKCED_01926 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OICMKCED_01927 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
OICMKCED_01928 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
OICMKCED_01929 6.7e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
OICMKCED_01930 1.2e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OICMKCED_01931 0.0 resE 2.7.13.3 T Histidine kinase
OICMKCED_01932 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
OICMKCED_01933 1.2e-192 rsiX
OICMKCED_01934 1e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
OICMKCED_01935 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OICMKCED_01936 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OICMKCED_01937 4.7e-41 fer C Ferredoxin
OICMKCED_01938 1.9e-200 ypbB 5.1.3.1 S protein conserved in bacteria
OICMKCED_01939 9.2e-286 recQ 3.6.4.12 L DNA helicase
OICMKCED_01940 2.2e-100 ypbD S metal-dependent membrane protease
OICMKCED_01941 1.3e-75 ypbE M Lysin motif
OICMKCED_01942 8.2e-81 ypbF S Protein of unknown function (DUF2663)
OICMKCED_01943 5.2e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
OICMKCED_01944 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OICMKCED_01945 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OICMKCED_01946 1.4e-173 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
OICMKCED_01947 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
OICMKCED_01948 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
OICMKCED_01949 8.4e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
OICMKCED_01950 2e-112 ypfA M Flagellar protein YcgR
OICMKCED_01951 1.8e-23 S Family of unknown function (DUF5359)
OICMKCED_01952 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OICMKCED_01953 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
OICMKCED_01954 2.6e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OICMKCED_01955 1e-07 S YpzI-like protein
OICMKCED_01956 1.3e-102 yphA
OICMKCED_01957 2.5e-161 seaA S YIEGIA protein
OICMKCED_01958 7.9e-28 ypzH
OICMKCED_01959 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OICMKCED_01960 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OICMKCED_01961 1.6e-18 yphE S Protein of unknown function (DUF2768)
OICMKCED_01962 6e-137 yphF
OICMKCED_01963 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OICMKCED_01964 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OICMKCED_01965 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
OICMKCED_01966 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
OICMKCED_01967 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
OICMKCED_01968 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
OICMKCED_01969 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OICMKCED_01970 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
OICMKCED_01971 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
OICMKCED_01972 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OICMKCED_01973 1.4e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OICMKCED_01974 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
OICMKCED_01975 3.6e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OICMKCED_01976 1.8e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OICMKCED_01977 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
OICMKCED_01978 3.3e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
OICMKCED_01979 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
OICMKCED_01980 4.7e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
OICMKCED_01981 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OICMKCED_01982 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
OICMKCED_01983 7.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
OICMKCED_01984 4.1e-234 S COG0457 FOG TPR repeat
OICMKCED_01985 2.8e-99 ypiB S Belongs to the UPF0302 family
OICMKCED_01986 8.5e-78 ypiF S Protein of unknown function (DUF2487)
OICMKCED_01987 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
OICMKCED_01988 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
OICMKCED_01989 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
OICMKCED_01990 2e-98 ypjA S membrane
OICMKCED_01991 6.1e-143 ypjB S sporulation protein
OICMKCED_01992 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
OICMKCED_01993 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
OICMKCED_01994 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OICMKCED_01995 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
OICMKCED_01996 6.9e-130 bshB1 S proteins, LmbE homologs
OICMKCED_01997 7.7e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
OICMKCED_01998 4.3e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OICMKCED_01999 2.5e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OICMKCED_02000 9.2e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
OICMKCED_02001 8e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OICMKCED_02002 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OICMKCED_02003 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
OICMKCED_02004 6.7e-23 ypmA S Protein of unknown function (DUF4264)
OICMKCED_02005 3.4e-80 ypmB S protein conserved in bacteria
OICMKCED_02006 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
OICMKCED_02007 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
OICMKCED_02008 1.1e-127 dnaD L DNA replication protein DnaD
OICMKCED_02009 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OICMKCED_02010 8.8e-92 ypoC
OICMKCED_02011 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
OICMKCED_02012 2.1e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OICMKCED_02013 1.8e-186 yppC S Protein of unknown function (DUF2515)
OICMKCED_02016 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
OICMKCED_02018 1e-47 yppG S YppG-like protein
OICMKCED_02019 7.3e-71 hspX O Belongs to the small heat shock protein (HSP20) family
OICMKCED_02020 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
OICMKCED_02021 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
OICMKCED_02022 5.1e-237 yprB L RNase_H superfamily
OICMKCED_02023 8.2e-91 ypsA S Belongs to the UPF0398 family
OICMKCED_02024 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OICMKCED_02025 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OICMKCED_02027 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
OICMKCED_02028 8.2e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OICMKCED_02029 1.4e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OICMKCED_02030 4.4e-186 ptxS K transcriptional
OICMKCED_02031 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
OICMKCED_02032 5e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
OICMKCED_02033 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
OICMKCED_02034 7.4e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OICMKCED_02035 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OICMKCED_02036 1.5e-226 pbuX F xanthine
OICMKCED_02037 2.8e-207 bcsA Q Naringenin-chalcone synthase
OICMKCED_02038 1.5e-86 ypbQ S protein conserved in bacteria
OICMKCED_02040 0.0 ypbR S Dynamin family
OICMKCED_02041 5.5e-37 ypbS S Protein of unknown function (DUF2533)
OICMKCED_02042 2e-07
OICMKCED_02043 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
OICMKCED_02045 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
OICMKCED_02046 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OICMKCED_02047 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
OICMKCED_02048 3e-29 ypeQ S Zinc-finger
OICMKCED_02049 8.1e-31 S Protein of unknown function (DUF2564)
OICMKCED_02050 3.8e-16 degR
OICMKCED_02051 7.9e-31 cspD K Cold-shock protein
OICMKCED_02052 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
OICMKCED_02053 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OICMKCED_02054 6.8e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
OICMKCED_02055 8.7e-105 ypgQ S phosphohydrolase
OICMKCED_02056 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
OICMKCED_02057 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
OICMKCED_02058 1.7e-75 yphP S Belongs to the UPF0403 family
OICMKCED_02059 5.9e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
OICMKCED_02060 8.6e-113 ypjP S YpjP-like protein
OICMKCED_02061 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OICMKCED_02062 1e-153 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OICMKCED_02063 1.6e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OICMKCED_02064 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OICMKCED_02065 4.2e-110 hlyIII S protein, Hemolysin III
OICMKCED_02066 1.6e-185 pspF K Transcriptional regulator
OICMKCED_02067 4.1e-242 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OICMKCED_02068 3.1e-40 ypmP S Protein of unknown function (DUF2535)
OICMKCED_02069 3.5e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
OICMKCED_02070 4.8e-137 ypmR E GDSL-like Lipase/Acylhydrolase
OICMKCED_02071 5e-99 ypmS S protein conserved in bacteria
OICMKCED_02072 5.5e-29 ypmT S Uncharacterized ympT
OICMKCED_02073 2.9e-222 mepA V MATE efflux family protein
OICMKCED_02074 1.6e-70 ypoP K transcriptional
OICMKCED_02075 1.7e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OICMKCED_02076 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
OICMKCED_02077 7.4e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
OICMKCED_02078 1.1e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
OICMKCED_02079 3.4e-185 cgeB S Spore maturation protein
OICMKCED_02080 1.5e-65 cgeA
OICMKCED_02081 3.5e-38 cgeC
OICMKCED_02082 1.1e-255 cgeD M maturation of the outermost layer of the spore
OICMKCED_02083 1e-142 yiiD K acetyltransferase
OICMKCED_02085 8.1e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OICMKCED_02086 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OICMKCED_02087 8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OICMKCED_02088 3.2e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
OICMKCED_02089 7.9e-154 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
OICMKCED_02090 5.1e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
OICMKCED_02091 8.3e-47 yokU S YokU-like protein, putative antitoxin
OICMKCED_02092 1.4e-36 yozE S Belongs to the UPF0346 family
OICMKCED_02093 1.6e-123 yodN
OICMKCED_02095 2.8e-24 yozD S YozD-like protein
OICMKCED_02096 1.7e-105 yodM 3.6.1.27 I Acid phosphatase homologues
OICMKCED_02097 3.6e-54 yodL S YodL-like
OICMKCED_02098 5.3e-09
OICMKCED_02099 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
OICMKCED_02100 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
OICMKCED_02101 5.2e-24 yodI
OICMKCED_02102 6.3e-128 yodH Q Methyltransferase
OICMKCED_02103 2.8e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
OICMKCED_02104 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OICMKCED_02105 6.2e-28 S Protein of unknown function (DUF3311)
OICMKCED_02106 1.3e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
OICMKCED_02107 6.5e-113 mhqD S Carboxylesterase
OICMKCED_02108 4.8e-108 yodC C nitroreductase
OICMKCED_02109 4.4e-55 yodB K transcriptional
OICMKCED_02110 1.8e-63 yodA S tautomerase
OICMKCED_02111 1.1e-205 gntP EG COG2610 H gluconate symporter and related permeases
OICMKCED_02112 3.4e-09
OICMKCED_02113 2e-56 yozR S COG0071 Molecular chaperone (small heat shock protein)
OICMKCED_02114 1.2e-160 rarD S -transporter
OICMKCED_02115 4.3e-43
OICMKCED_02116 2.2e-60 yojF S Protein of unknown function (DUF1806)
OICMKCED_02117 2.8e-125 yojG S deacetylase
OICMKCED_02118 1.2e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OICMKCED_02119 1.7e-241 norM V Multidrug efflux pump
OICMKCED_02121 1.4e-107 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OICMKCED_02122 1.5e-225 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
OICMKCED_02123 1.2e-190 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OICMKCED_02124 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OICMKCED_02125 2.1e-160 yojN S ATPase family associated with various cellular activities (AAA)
OICMKCED_02126 0.0 yojO P Von Willebrand factor
OICMKCED_02127 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
OICMKCED_02128 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
OICMKCED_02129 5.1e-168 yocS S -transporter
OICMKCED_02130 5.5e-229 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OICMKCED_02131 9.6e-163 sodA 1.15.1.1 P Superoxide dismutase
OICMKCED_02132 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
OICMKCED_02133 1.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
OICMKCED_02134 2.7e-31 yozC
OICMKCED_02135 4.2e-56 yozO S Bacterial PH domain
OICMKCED_02136 1.9e-36 yocN
OICMKCED_02137 1.1e-40 yozN
OICMKCED_02138 1.8e-86 yocM O Belongs to the small heat shock protein (HSP20) family
OICMKCED_02139 2e-30
OICMKCED_02140 1.4e-53 yocL
OICMKCED_02141 7.4e-83 dksA T general stress protein
OICMKCED_02142 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OICMKCED_02143 0.0 recQ 3.6.4.12 L DNA helicase
OICMKCED_02144 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
OICMKCED_02145 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OICMKCED_02146 4.6e-197 desK 2.7.13.3 T Histidine kinase
OICMKCED_02147 4.5e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
OICMKCED_02148 9.3e-186 yocD 3.4.17.13 V peptidase S66
OICMKCED_02149 1.6e-93 yocC
OICMKCED_02150 1.1e-144
OICMKCED_02151 1.5e-92 yozB S membrane
OICMKCED_02152 1.7e-117 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OICMKCED_02153 1e-51 czrA K transcriptional
OICMKCED_02154 8.8e-93 yobW
OICMKCED_02155 9.3e-175 yobV K WYL domain
OICMKCED_02156 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
OICMKCED_02157 1e-130 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
OICMKCED_02158 1.3e-97 yobS K Transcriptional regulator
OICMKCED_02159 1.1e-141 yobR 2.3.1.1 J FR47-like protein
OICMKCED_02160 2.3e-133 yobQ K helix_turn_helix, arabinose operon control protein
OICMKCED_02161 7.8e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
OICMKCED_02162 0.0 yobO M Pectate lyase superfamily protein
OICMKCED_02163 3.7e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
OICMKCED_02164 4.8e-102 yokH G SMI1 / KNR4 family
OICMKCED_02165 1.7e-39 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OICMKCED_02170 1.4e-37 S TM2 domain
OICMKCED_02171 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
OICMKCED_02172 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
OICMKCED_02175 2.2e-168 bla 3.5.2.6 V beta-lactamase
OICMKCED_02176 4.7e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
OICMKCED_02177 1e-75 yoaW
OICMKCED_02178 3.7e-157 yijE EG EamA-like transporter family
OICMKCED_02179 5.6e-158 yoaU K LysR substrate binding domain
OICMKCED_02180 1.1e-147 yoaT S Protein of unknown function (DUF817)
OICMKCED_02181 1.6e-36 yozG K Transcriptional regulator
OICMKCED_02182 2.8e-74 yoaS S Protein of unknown function (DUF2975)
OICMKCED_02183 7.1e-172 yoaR V vancomycin resistance protein
OICMKCED_02184 3e-87
OICMKCED_02186 3.5e-51 yoaQ S Evidence 4 Homologs of previously reported genes of
OICMKCED_02187 1.5e-143 yoaP 3.1.3.18 K YoaP-like
OICMKCED_02189 5.6e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
OICMKCED_02192 1.6e-131 yoqW S Belongs to the SOS response-associated peptidase family
OICMKCED_02193 7.3e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
OICMKCED_02194 6.8e-111 yoaK S Membrane
OICMKCED_02195 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
OICMKCED_02196 8.1e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
OICMKCED_02197 1.9e-178 mcpU NT methyl-accepting chemotaxis protein
OICMKCED_02198 8.2e-37 S Protein of unknown function (DUF4025)
OICMKCED_02199 2.6e-13
OICMKCED_02200 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
OICMKCED_02201 1.9e-33 yoaF
OICMKCED_02202 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OICMKCED_02203 2.9e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OICMKCED_02204 2.2e-279 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
OICMKCED_02205 8.9e-234 yoaB EGP Major facilitator Superfamily
OICMKCED_02206 2e-49 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OICMKCED_02207 3.1e-128 yoxB
OICMKCED_02208 3.5e-38 yoxC S Bacterial protein of unknown function (DUF948)
OICMKCED_02209 9.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
OICMKCED_02210 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
OICMKCED_02211 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OICMKCED_02212 7.8e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OICMKCED_02213 7.8e-155 gltC K Transcriptional regulator
OICMKCED_02214 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
OICMKCED_02215 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
OICMKCED_02216 6.7e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
OICMKCED_02217 1.1e-153 gltR1 K Transcriptional regulator
OICMKCED_02218 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OICMKCED_02219 3e-34 yoeD G Helix-turn-helix domain
OICMKCED_02220 2.2e-96 L Integrase
OICMKCED_02222 1.8e-98 yoeB S IseA DL-endopeptidase inhibitor
OICMKCED_02223 2.3e-246 yoeA V MATE efflux family protein
OICMKCED_02224 2.1e-190 yoxA 5.1.3.3 G Aldose 1-epimerase
OICMKCED_02225 6.8e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
OICMKCED_02226 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OICMKCED_02227 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
OICMKCED_02228 2.8e-64 yngL S Protein of unknown function (DUF1360)
OICMKCED_02229 1.9e-302 yngK T Glycosyl hydrolase-like 10
OICMKCED_02230 1.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
OICMKCED_02231 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OICMKCED_02232 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
OICMKCED_02233 1.7e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
OICMKCED_02234 1.5e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
OICMKCED_02235 3.2e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OICMKCED_02236 4.5e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OICMKCED_02237 3.3e-233 nrnB S phosphohydrolase (DHH superfamily)
OICMKCED_02238 5.5e-104 yngC S membrane-associated protein
OICMKCED_02239 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OICMKCED_02240 2e-79 yngA S membrane
OICMKCED_02241 4.7e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
OICMKCED_02242 2e-249 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
OICMKCED_02244 5.4e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
OICMKCED_02245 1.8e-251 agcS E Sodium alanine symporter
OICMKCED_02246 1.3e-57 ynfC
OICMKCED_02247 2.3e-12
OICMKCED_02248 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OICMKCED_02249 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OICMKCED_02250 6.6e-69 yccU S CoA-binding protein
OICMKCED_02251 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OICMKCED_02252 4.1e-49 yneR S Belongs to the HesB IscA family
OICMKCED_02253 1.9e-52 yneQ
OICMKCED_02254 2.7e-73 yneP S Thioesterase-like superfamily
OICMKCED_02255 3.9e-35 tlp S Belongs to the Tlp family
OICMKCED_02256 3.1e-08 sspN S Small acid-soluble spore protein N family
OICMKCED_02258 5.9e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OICMKCED_02259 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OICMKCED_02260 2.2e-14 sspO S Belongs to the SspO family
OICMKCED_02261 3.9e-19 sspP S Belongs to the SspP family
OICMKCED_02262 5.9e-64 hspX O Spore coat protein
OICMKCED_02263 7.2e-74 yneK S Protein of unknown function (DUF2621)
OICMKCED_02264 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
OICMKCED_02265 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
OICMKCED_02266 2.1e-126 ccdA O cytochrome c biogenesis protein
OICMKCED_02267 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
OICMKCED_02268 1.8e-28 yneF S UPF0154 protein
OICMKCED_02269 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
OICMKCED_02270 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OICMKCED_02271 1.3e-32 ynzC S UPF0291 protein
OICMKCED_02272 4.5e-112 yneB L resolvase
OICMKCED_02273 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
OICMKCED_02274 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OICMKCED_02275 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
OICMKCED_02276 5.8e-74 yndM S Protein of unknown function (DUF2512)
OICMKCED_02277 4.7e-137 yndL S Replication protein
OICMKCED_02279 1.8e-306 yndJ S YndJ-like protein
OICMKCED_02280 8.4e-116 yndH S Domain of unknown function (DUF4166)
OICMKCED_02281 2.5e-152 yndG S DoxX-like family
OICMKCED_02282 3.6e-219 gerLC S Spore germination protein
OICMKCED_02283 1.1e-59 gerAB U Spore germination
OICMKCED_02284 2.9e-123 gerAB U Spore germination
OICMKCED_02285 3.4e-183 gerAA EG Spore germination protein
OICMKCED_02286 6.5e-78 gerAA EG Spore germination protein
OICMKCED_02289 5.8e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
OICMKCED_02290 6.9e-71
OICMKCED_02291 7.9e-25 tatA U protein secretion
OICMKCED_02294 7.2e-130 S Domain of unknown function, YrpD
OICMKCED_02296 8.6e-164 S Thymidylate synthase
OICMKCED_02299 5.2e-15
OICMKCED_02300 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
OICMKCED_02301 2e-82 yncE S Protein of unknown function (DUF2691)
OICMKCED_02302 8.5e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OICMKCED_02303 1.8e-254 iolT EGP Major facilitator Superfamily
OICMKCED_02304 1.1e-110 yokF 3.1.31.1 L RNA catabolic process
OICMKCED_02305 3.3e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
OICMKCED_02306 3.2e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
OICMKCED_02307 3.1e-212 xylR GK ROK family
OICMKCED_02308 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
OICMKCED_02309 1.1e-253 xynT G MFS/sugar transport protein
OICMKCED_02310 2.2e-37 yhbS S family acetyltransferase
OICMKCED_02311 3.2e-75 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
OICMKCED_02314 1.7e-111 ynaE S Domain of unknown function (DUF3885)
OICMKCED_02315 1.5e-22 K Cro/C1-type HTH DNA-binding domain
OICMKCED_02316 4.7e-08 S Uncharacterised protein family (UPF0715)
OICMKCED_02317 3.4e-73 S CAAX protease self-immunity
OICMKCED_02319 1.9e-95 ynaD J Acetyltransferase (GNAT) domain
OICMKCED_02321 9.3e-216 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
OICMKCED_02322 2.3e-196 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OICMKCED_02323 2.2e-120 H Methionine biosynthesis protein MetW
OICMKCED_02324 2.2e-93 M Glycosyltransferase like family
OICMKCED_02325 1.5e-69 Q Collagen triple helix repeat (20 copies)
OICMKCED_02326 2.3e-10 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OICMKCED_02327 6.6e-31
OICMKCED_02328 3.8e-10
OICMKCED_02329 7e-261 glnA 6.3.1.2 E glutamine synthetase
OICMKCED_02330 1.1e-68 glnR K transcriptional
OICMKCED_02331 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
OICMKCED_02332 6.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OICMKCED_02333 8.7e-69 spoVK O stage V sporulation protein K
OICMKCED_02334 5.3e-245 cisA2 L Recombinase
OICMKCED_02336 1.1e-93 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OICMKCED_02337 4.1e-10 K Cro/C1-type HTH DNA-binding domain
OICMKCED_02346 9.7e-160 S Calcineurin-like phosphoesterase
OICMKCED_02347 1.4e-28 sspB S spore protein
OICMKCED_02350 7e-36
OICMKCED_02352 5.4e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OICMKCED_02353 1.5e-160 S Thymidylate synthase
OICMKCED_02358 3.6e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
OICMKCED_02359 1.1e-09
OICMKCED_02360 1.7e-35 O Glutaredoxin
OICMKCED_02361 3.4e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OICMKCED_02363 3.3e-172 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OICMKCED_02364 3.8e-178 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OICMKCED_02365 1.5e-62 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
OICMKCED_02367 3.3e-135 S HNH endonuclease
OICMKCED_02377 3.3e-13
OICMKCED_02382 5.7e-146 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
OICMKCED_02384 8.7e-90 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
OICMKCED_02385 1.6e-85 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
OICMKCED_02390 2.7e-113 DR0488 S protein conserved in bacteria
OICMKCED_02391 0.0 S Bacterial DNA polymerase III alpha subunit
OICMKCED_02392 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OICMKCED_02393 4.5e-224 L DNA primase activity
OICMKCED_02394 9.7e-283 3.6.4.12 J DnaB-like helicase C terminal domain
OICMKCED_02395 5.3e-86
OICMKCED_02396 7.6e-180 L AAA domain
OICMKCED_02397 3.6e-155
OICMKCED_02401 0.0 M Parallel beta-helix repeats
OICMKCED_02402 5.7e-144 S Pfam:DUF867
OICMKCED_02405 1e-159
OICMKCED_02407 1.5e-126 yoqW S Belongs to the SOS response-associated peptidase family
OICMKCED_02408 3.7e-148 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
OICMKCED_02410 8.3e-27
OICMKCED_02411 1.8e-87
OICMKCED_02414 1.6e-72
OICMKCED_02417 1.2e-22
OICMKCED_02426 6.2e-42
OICMKCED_02430 1.1e-33 K Transcriptional regulator
OICMKCED_02431 4.6e-177
OICMKCED_02432 1.1e-261 S DNA-sulfur modification-associated
OICMKCED_02433 5.4e-195 L Belongs to the 'phage' integrase family
OICMKCED_02438 3.1e-103
OICMKCED_02439 3.9e-35 V HNH endonuclease
OICMKCED_02442 6.2e-31
OICMKCED_02443 5.3e-13
OICMKCED_02449 1.4e-27 K Cro/C1-type HTH DNA-binding domain
OICMKCED_02454 9.4e-204
OICMKCED_02456 4.3e-16
OICMKCED_02457 1.3e-51 bldD K domain, Protein
OICMKCED_02459 0.0
OICMKCED_02460 1.9e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OICMKCED_02462 9e-199 S Calcineurin-like phosphoesterase superfamily domain
OICMKCED_02466 6.4e-17
OICMKCED_02467 9.6e-109
OICMKCED_02468 2.8e-19
OICMKCED_02469 9.3e-36
OICMKCED_02471 3.3e-70
OICMKCED_02474 2.8e-69
OICMKCED_02475 1.7e-90
OICMKCED_02476 6.9e-130
OICMKCED_02477 1.5e-88
OICMKCED_02480 1.2e-45
OICMKCED_02481 1.5e-35 S Domain of unknown function (DUF2479)
OICMKCED_02482 2.1e-08
OICMKCED_02483 1.6e-07 S Phage uncharacterised protein (Phage_XkdX)
OICMKCED_02484 1.3e-98 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
OICMKCED_02485 9.4e-54
OICMKCED_02486 2.3e-56
OICMKCED_02487 2.2e-190 xerH A Belongs to the 'phage' integrase family
OICMKCED_02489 3.6e-25 K acetyltransferase
OICMKCED_02494 3.7e-18
OICMKCED_02495 2.4e-108
OICMKCED_02496 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OICMKCED_02497 3.8e-86 S Phage tail protein
OICMKCED_02498 7.3e-294 S Pfam Transposase IS66
OICMKCED_02499 2.2e-119
OICMKCED_02500 1e-183 M Pectate lyase superfamily protein
OICMKCED_02501 5.5e-75 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OICMKCED_02502 4.4e-32 bhlA S BhlA holin family
OICMKCED_02503 5.5e-40 S SPP1 phage holin
OICMKCED_02504 3.4e-74 O protein disulfide oxidoreductase activity
OICMKCED_02505 2.9e-240 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OICMKCED_02506 1.2e-70 CO cell redox homeostasis
OICMKCED_02507 0.0 V Peptidase C39 family
OICMKCED_02509 1.5e-233 S impB/mucB/samB family C-terminal domain
OICMKCED_02510 8.4e-54 S YolD-like protein
OICMKCED_02514 6.8e-100 S aspartate phosphatase
OICMKCED_02515 1.8e-91 yokK S SMI1 / KNR4 family
OICMKCED_02516 8.2e-76 S SMI1-KNR4 cell-wall
OICMKCED_02517 1.7e-172 yobL S Bacterial EndoU nuclease
OICMKCED_02518 2.2e-64 G SMI1-KNR4 cell-wall
OICMKCED_02519 1.9e-108 yokF 3.1.31.1 L RNA catabolic process
OICMKCED_02520 2.2e-80 yhbS S family acetyltransferase
OICMKCED_02522 2.4e-97 spoVK O stage V sporulation protein K
OICMKCED_02523 6.3e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OICMKCED_02524 1e-108 ymaB
OICMKCED_02525 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OICMKCED_02526 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OICMKCED_02527 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
OICMKCED_02528 4.3e-22 ymzA
OICMKCED_02529 8.2e-23
OICMKCED_02530 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
OICMKCED_02531 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OICMKCED_02532 2.1e-46 ymaF S YmaF family
OICMKCED_02534 5.4e-50 ebrA P Small Multidrug Resistance protein
OICMKCED_02535 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
OICMKCED_02536 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
OICMKCED_02537 2.1e-126 ymaC S Replication protein
OICMKCED_02538 1.9e-07 K Transcriptional regulator
OICMKCED_02539 1.5e-250 aprX O Belongs to the peptidase S8 family
OICMKCED_02540 8.9e-161 ymaE S Metallo-beta-lactamase superfamily
OICMKCED_02541 4.4e-61 ymzB
OICMKCED_02542 1.4e-231 cypA C Cytochrome P450
OICMKCED_02543 0.0 pks13 HQ Beta-ketoacyl synthase
OICMKCED_02544 0.0 dhbF IQ polyketide synthase
OICMKCED_02545 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
OICMKCED_02546 0.0 pfaA Q Polyketide synthase of type I
OICMKCED_02547 0.0 rhiB IQ polyketide synthase
OICMKCED_02548 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
OICMKCED_02549 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
OICMKCED_02550 1.3e-245 pksG 2.3.3.10 I synthase
OICMKCED_02551 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OICMKCED_02552 1.4e-37 acpK IQ Phosphopantetheine attachment site
OICMKCED_02553 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OICMKCED_02554 1.2e-185 pksD Q Acyl transferase domain
OICMKCED_02555 2.9e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OICMKCED_02556 2.1e-128 pksB 3.1.2.6 S Polyketide biosynthesis
OICMKCED_02557 4.4e-109 pksA K Transcriptional regulator
OICMKCED_02558 3.9e-96 ymcC S Membrane
OICMKCED_02559 2.6e-69 S Regulatory protein YrvL
OICMKCED_02561 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OICMKCED_02562 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OICMKCED_02563 2.2e-88 cotE S Spore coat protein
OICMKCED_02564 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
OICMKCED_02565 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OICMKCED_02566 2.5e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OICMKCED_02567 3.9e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
OICMKCED_02568 1.2e-36 spoVS S Stage V sporulation protein S
OICMKCED_02569 1.9e-152 ymdB S protein conserved in bacteria
OICMKCED_02570 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
OICMKCED_02571 8.8e-215 pbpX V Beta-lactamase
OICMKCED_02572 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OICMKCED_02573 2.5e-236 cinA 3.5.1.42 S Belongs to the CinA family
OICMKCED_02574 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OICMKCED_02575 1.9e-124 ymfM S protein conserved in bacteria
OICMKCED_02576 2.7e-143 ymfK S Protein of unknown function (DUF3388)
OICMKCED_02577 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
OICMKCED_02578 2.7e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
OICMKCED_02579 5.1e-240 ymfH S zinc protease
OICMKCED_02580 7e-234 ymfF S Peptidase M16
OICMKCED_02581 6.5e-205 ymfD EGP Major facilitator Superfamily
OICMKCED_02582 1.4e-133 ymfC K Transcriptional regulator
OICMKCED_02583 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OICMKCED_02584 4.4e-32 S YlzJ-like protein
OICMKCED_02585 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
OICMKCED_02586 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OICMKCED_02587 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OICMKCED_02588 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OICMKCED_02589 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OICMKCED_02590 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
OICMKCED_02591 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
OICMKCED_02592 2.6e-42 ymxH S YlmC YmxH family
OICMKCED_02593 4.4e-233 pepR S Belongs to the peptidase M16 family
OICMKCED_02594 7e-178 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
OICMKCED_02595 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
OICMKCED_02596 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OICMKCED_02597 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
OICMKCED_02598 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OICMKCED_02599 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OICMKCED_02600 3.9e-44 ylxP S protein conserved in bacteria
OICMKCED_02601 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OICMKCED_02602 3.1e-47 ylxQ J ribosomal protein
OICMKCED_02603 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
OICMKCED_02604 1.1e-203 nusA K Participates in both transcription termination and antitermination
OICMKCED_02605 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
OICMKCED_02606 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OICMKCED_02607 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OICMKCED_02608 7.7e-233 rasP M zinc metalloprotease
OICMKCED_02609 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
OICMKCED_02610 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
OICMKCED_02611 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OICMKCED_02612 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OICMKCED_02613 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OICMKCED_02614 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OICMKCED_02615 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
OICMKCED_02616 1.2e-75 ylxL
OICMKCED_02617 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OICMKCED_02618 2.5e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
OICMKCED_02619 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
OICMKCED_02620 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
OICMKCED_02621 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
OICMKCED_02622 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
OICMKCED_02623 7.5e-158 flhG D Belongs to the ParA family
OICMKCED_02624 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
OICMKCED_02625 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OICMKCED_02626 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OICMKCED_02627 3.6e-132 fliR N Flagellar biosynthetic protein FliR
OICMKCED_02628 2.2e-36 fliQ N Role in flagellar biosynthesis
OICMKCED_02629 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
OICMKCED_02630 2.1e-96 fliZ N Flagellar biosynthesis protein, FliO
OICMKCED_02631 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
OICMKCED_02632 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OICMKCED_02633 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OICMKCED_02634 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
OICMKCED_02635 8.2e-140 flgG N Flagellar basal body rod
OICMKCED_02636 1.7e-72 flgD N Flagellar basal body rod modification protein
OICMKCED_02637 4.4e-216 fliK N Flagellar hook-length control protein
OICMKCED_02638 7.7e-37 ylxF S MgtE intracellular N domain
OICMKCED_02639 1.5e-69 fliJ N Flagellar biosynthesis chaperone
OICMKCED_02640 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
OICMKCED_02641 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
OICMKCED_02642 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OICMKCED_02643 2.6e-254 fliF N The M ring may be actively involved in energy transduction
OICMKCED_02644 1.9e-31 fliE N Flagellar hook-basal body
OICMKCED_02645 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
OICMKCED_02646 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
OICMKCED_02647 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OICMKCED_02648 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OICMKCED_02649 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OICMKCED_02650 2.5e-169 xerC L tyrosine recombinase XerC
OICMKCED_02651 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OICMKCED_02652 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OICMKCED_02653 4.7e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
OICMKCED_02654 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OICMKCED_02655 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
OICMKCED_02656 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
OICMKCED_02657 6.1e-289 ylqG
OICMKCED_02658 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OICMKCED_02659 1.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OICMKCED_02660 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OICMKCED_02661 2.1e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
OICMKCED_02662 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OICMKCED_02663 6.3e-61 ylqD S YlqD protein
OICMKCED_02664 4.5e-36 ylqC S Belongs to the UPF0109 family
OICMKCED_02665 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
OICMKCED_02666 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OICMKCED_02667 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OICMKCED_02668 2.9e-87
OICMKCED_02669 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OICMKCED_02670 0.0 smc D Required for chromosome condensation and partitioning
OICMKCED_02671 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OICMKCED_02672 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OICMKCED_02673 6.1e-129 IQ reductase
OICMKCED_02674 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OICMKCED_02675 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OICMKCED_02676 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
OICMKCED_02677 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OICMKCED_02678 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
OICMKCED_02679 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
OICMKCED_02680 4.3e-300 yloV S kinase related to dihydroxyacetone kinase
OICMKCED_02681 5.5e-59 asp S protein conserved in bacteria
OICMKCED_02682 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OICMKCED_02683 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
OICMKCED_02684 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
OICMKCED_02685 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OICMKCED_02686 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
OICMKCED_02687 1.6e-140 stp 3.1.3.16 T phosphatase
OICMKCED_02688 1.4e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
OICMKCED_02689 2.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OICMKCED_02690 7.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OICMKCED_02691 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OICMKCED_02692 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OICMKCED_02693 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OICMKCED_02694 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OICMKCED_02695 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
OICMKCED_02696 1.5e-40 ylzA S Belongs to the UPF0296 family
OICMKCED_02697 3.1e-156 yloC S stress-induced protein
OICMKCED_02698 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
OICMKCED_02699 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
OICMKCED_02700 1.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
OICMKCED_02701 4.9e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
OICMKCED_02702 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OICMKCED_02703 6.2e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
OICMKCED_02704 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OICMKCED_02705 5.4e-179 cysP P phosphate transporter
OICMKCED_02706 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OICMKCED_02708 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OICMKCED_02709 3.3e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OICMKCED_02710 1.3e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OICMKCED_02711 1.2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
OICMKCED_02712 0.0 carB 6.3.5.5 F Belongs to the CarB family
OICMKCED_02713 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OICMKCED_02714 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OICMKCED_02715 1.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OICMKCED_02716 1.3e-230 pyrP F Xanthine uracil
OICMKCED_02717 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OICMKCED_02718 1.9e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OICMKCED_02719 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OICMKCED_02720 1.3e-63 dksA T COG1734 DnaK suppressor protein
OICMKCED_02721 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OICMKCED_02722 2.6e-67 divIVA D Cell division initiation protein
OICMKCED_02723 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
OICMKCED_02724 1.3e-39 yggT S membrane
OICMKCED_02725 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OICMKCED_02726 2.5e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OICMKCED_02727 2.3e-156 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
OICMKCED_02728 2.4e-37 ylmC S sporulation protein
OICMKCED_02729 1.2e-249 argE 3.5.1.16 E Acetylornithine deacetylase
OICMKCED_02730 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
OICMKCED_02731 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OICMKCED_02732 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OICMKCED_02733 2.8e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
OICMKCED_02734 0.0 bpr O COG1404 Subtilisin-like serine proteases
OICMKCED_02735 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OICMKCED_02736 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OICMKCED_02737 6.2e-58 sbp S small basic protein
OICMKCED_02738 1.8e-91 ylxX S protein conserved in bacteria
OICMKCED_02739 4.1e-103 ylxW S protein conserved in bacteria
OICMKCED_02740 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OICMKCED_02741 1.5e-166 murB 1.3.1.98 M cell wall formation
OICMKCED_02742 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OICMKCED_02743 5.7e-186 spoVE D Belongs to the SEDS family
OICMKCED_02744 8.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OICMKCED_02745 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OICMKCED_02746 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OICMKCED_02747 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
OICMKCED_02748 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
OICMKCED_02749 3.7e-44 ftsL D Essential cell division protein
OICMKCED_02750 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OICMKCED_02751 2.9e-78 mraZ K Belongs to the MraZ family
OICMKCED_02752 2.1e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OICMKCED_02753 4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OICMKCED_02754 1.5e-88 ylbP K n-acetyltransferase
OICMKCED_02755 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
OICMKCED_02756 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
OICMKCED_02757 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
OICMKCED_02759 2.8e-235 ylbM S Belongs to the UPF0348 family
OICMKCED_02760 2e-186 ylbL T Belongs to the peptidase S16 family
OICMKCED_02761 1.3e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
OICMKCED_02762 1.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
OICMKCED_02763 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OICMKCED_02764 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
OICMKCED_02765 3.7e-38 ylbG S UPF0298 protein
OICMKCED_02766 1.8e-75 ylbF S Belongs to the UPF0342 family
OICMKCED_02767 6.7e-37 ylbE S YlbE-like protein
OICMKCED_02768 4.1e-63 ylbD S Putative coat protein
OICMKCED_02769 4.3e-200 ylbC S protein with SCP PR1 domains
OICMKCED_02770 2.6e-74 ylbB T COG0517 FOG CBS domain
OICMKCED_02771 7e-62 ylbA S YugN-like family
OICMKCED_02772 8.8e-167 ctaG S cytochrome c oxidase
OICMKCED_02773 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
OICMKCED_02774 2.8e-111 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
OICMKCED_02775 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OICMKCED_02776 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
OICMKCED_02777 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OICMKCED_02778 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
OICMKCED_02779 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OICMKCED_02780 1.9e-212 ftsW D Belongs to the SEDS family
OICMKCED_02781 8.7e-44 ylaN S Belongs to the UPF0358 family
OICMKCED_02782 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
OICMKCED_02783 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OICMKCED_02784 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
OICMKCED_02785 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OICMKCED_02786 2.5e-32 ylaI S protein conserved in bacteria
OICMKCED_02787 4.2e-47 ylaH S YlaH-like protein
OICMKCED_02788 0.0 typA T GTP-binding protein TypA
OICMKCED_02789 8.2e-22 S Family of unknown function (DUF5325)
OICMKCED_02790 3.8e-36 ylaE
OICMKCED_02791 3.5e-11 sigC S Putative zinc-finger
OICMKCED_02792 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
OICMKCED_02793 1.9e-40 ylaB
OICMKCED_02794 0.0 ylaA
OICMKCED_02795 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
OICMKCED_02796 2.3e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OICMKCED_02797 5.8e-77 ykzC S Acetyltransferase (GNAT) family
OICMKCED_02798 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
OICMKCED_02799 7.1e-26 ykzI
OICMKCED_02800 2.1e-117 yktB S Belongs to the UPF0637 family
OICMKCED_02801 2e-42 yktA S Belongs to the UPF0223 family
OICMKCED_02802 1.3e-276 speA 4.1.1.19 E Arginine
OICMKCED_02803 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
OICMKCED_02804 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OICMKCED_02805 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OICMKCED_02806 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OICMKCED_02807 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OICMKCED_02808 4.6e-109 recN L Putative cell-wall binding lipoprotein
OICMKCED_02810 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OICMKCED_02811 1.6e-146 ykrA S hydrolases of the HAD superfamily
OICMKCED_02812 8.2e-31 ykzG S Belongs to the UPF0356 family
OICMKCED_02813 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OICMKCED_02814 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OICMKCED_02815 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
OICMKCED_02816 1.2e-157 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
OICMKCED_02817 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
OICMKCED_02818 1.5e-43 abrB K of stationary sporulation gene expression
OICMKCED_02819 7.7e-183 mreB D Rod-share determining protein MreBH
OICMKCED_02820 1.1e-12 S Uncharacterized protein YkpC
OICMKCED_02821 4.5e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
OICMKCED_02822 4.8e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OICMKCED_02823 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OICMKCED_02824 8.1e-39 ykoA
OICMKCED_02825 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OICMKCED_02826 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
OICMKCED_02827 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
OICMKCED_02828 3.1e-136 fruR K Transcriptional regulator
OICMKCED_02829 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
OICMKCED_02830 2.5e-124 macB V ABC transporter, ATP-binding protein
OICMKCED_02831 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OICMKCED_02832 1e-117 yknW S Yip1 domain
OICMKCED_02833 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
OICMKCED_02834 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
OICMKCED_02835 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OICMKCED_02836 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
OICMKCED_02837 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
OICMKCED_02838 1.7e-243 moeA 2.10.1.1 H molybdopterin
OICMKCED_02839 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OICMKCED_02840 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
OICMKCED_02841 8.4e-147 yknT
OICMKCED_02842 5.8e-95 rok K Repressor of ComK
OICMKCED_02843 6.3e-81 ykuV CO thiol-disulfide
OICMKCED_02844 3.9e-101 ykuU O Alkyl hydroperoxide reductase
OICMKCED_02845 8.8e-142 ykuT M Mechanosensitive ion channel
OICMKCED_02846 9e-37 ykuS S Belongs to the UPF0180 family
OICMKCED_02847 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OICMKCED_02848 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OICMKCED_02849 4.2e-80 fld C Flavodoxin
OICMKCED_02850 3.2e-177 ykuO
OICMKCED_02851 3.7e-87 fld C Flavodoxin domain
OICMKCED_02852 3.5e-168 ccpC K Transcriptional regulator
OICMKCED_02853 1.6e-76 ykuL S CBS domain
OICMKCED_02854 3.9e-27 ykzF S Antirepressor AbbA
OICMKCED_02855 4.4e-94 ykuK S Ribonuclease H-like
OICMKCED_02856 3.9e-37 ykuJ S protein conserved in bacteria
OICMKCED_02857 5.2e-234 ykuI T Diguanylate phosphodiesterase
OICMKCED_02858 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OICMKCED_02859 9.4e-166 ykuE S Metallophosphoesterase
OICMKCED_02860 1.8e-87 ykuD S protein conserved in bacteria
OICMKCED_02861 9.9e-236 ykuC EGP Major facilitator Superfamily
OICMKCED_02862 1.7e-84 ykyB S YkyB-like protein
OICMKCED_02863 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
OICMKCED_02864 2.2e-15
OICMKCED_02865 8.8e-223 patA 2.6.1.1 E Aminotransferase
OICMKCED_02866 0.0 pilS 2.7.13.3 T Histidine kinase
OICMKCED_02867 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
OICMKCED_02868 5.7e-122 ykwD J protein with SCP PR1 domains
OICMKCED_02869 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
OICMKCED_02870 1.9e-262 mcpC NT chemotaxis protein
OICMKCED_02871 1.1e-129 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OICMKCED_02872 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
OICMKCED_02873 7.2e-39 splA S Transcriptional regulator
OICMKCED_02874 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OICMKCED_02875 2.1e-39 ptsH G phosphocarrier protein HPr
OICMKCED_02876 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OICMKCED_02877 7.6e-128 glcT K antiterminator
OICMKCED_02879 8.3e-179 ykvZ 5.1.1.1 K Transcriptional regulator
OICMKCED_02880 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OICMKCED_02881 1e-09
OICMKCED_02882 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OICMKCED_02883 1.6e-88 stoA CO thiol-disulfide
OICMKCED_02884 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OICMKCED_02885 2e-101 ykvT 3.5.1.28 M Cell Wall Hydrolase
OICMKCED_02886 2.8e-28
OICMKCED_02887 6e-25 ykvS S protein conserved in bacteria
OICMKCED_02888 1.4e-44 ykvR S Protein of unknown function (DUF3219)
OICMKCED_02889 4.4e-161 G Glycosyl hydrolases family 18
OICMKCED_02890 6e-35 3.5.1.104 M LysM domain
OICMKCED_02891 2.4e-214 ykvP 3.5.1.28 M Glycosyl transferases group 1
OICMKCED_02892 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
OICMKCED_02893 3.4e-61 ykvN K Transcriptional regulator
OICMKCED_02894 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OICMKCED_02895 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
OICMKCED_02896 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
OICMKCED_02897 6.2e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OICMKCED_02898 1.8e-179 ykvI S membrane
OICMKCED_02899 0.0 clpE O Belongs to the ClpA ClpB family
OICMKCED_02900 1e-137 motA N flagellar motor
OICMKCED_02901 2.5e-125 motB N Flagellar motor protein
OICMKCED_02902 1.3e-75 ykvE K transcriptional
OICMKCED_02903 1.4e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
OICMKCED_02904 2.6e-63 eag
OICMKCED_02905 7.5e-10 S Spo0E like sporulation regulatory protein
OICMKCED_02906 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
OICMKCED_02907 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OICMKCED_02908 3.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
OICMKCED_02909 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OICMKCED_02910 4.5e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
OICMKCED_02911 2.6e-230 mtnE 2.6.1.83 E Aminotransferase
OICMKCED_02912 1.7e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OICMKCED_02913 7e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OICMKCED_02914 3.1e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OICMKCED_02916 2.7e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OICMKCED_02917 0.0 kinE 2.7.13.3 T Histidine kinase
OICMKCED_02918 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
OICMKCED_02919 4.1e-18 ykzE
OICMKCED_02920 1.2e-10 ydfR S Protein of unknown function (DUF421)
OICMKCED_02921 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
OICMKCED_02922 3.9e-154 htpX O Belongs to the peptidase M48B family
OICMKCED_02923 1.5e-124 ykrK S Domain of unknown function (DUF1836)
OICMKCED_02924 1.9e-26 sspD S small acid-soluble spore protein
OICMKCED_02925 4.4e-110 rsgI S Anti-sigma factor N-terminus
OICMKCED_02926 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OICMKCED_02927 4.6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
OICMKCED_02928 2.7e-109 ykoX S membrane-associated protein
OICMKCED_02929 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
OICMKCED_02930 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OICMKCED_02931 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
OICMKCED_02932 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OICMKCED_02933 0.0 ykoS
OICMKCED_02934 2.1e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
OICMKCED_02935 3.7e-99 ykoP G polysaccharide deacetylase
OICMKCED_02936 8.9e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
OICMKCED_02937 1.3e-81 mhqR K transcriptional
OICMKCED_02938 6.9e-26 ykoL
OICMKCED_02939 5.9e-18
OICMKCED_02940 1.4e-53 tnrA K transcriptional
OICMKCED_02941 2.2e-222 mgtE P Acts as a magnesium transporter
OICMKCED_02944 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
OICMKCED_02945 2.1e-112 ykoI S Peptidase propeptide and YPEB domain
OICMKCED_02946 1.1e-240 ykoH 2.7.13.3 T Histidine kinase
OICMKCED_02947 3.9e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OICMKCED_02948 6.9e-107 ykoF S YKOF-related Family
OICMKCED_02949 2.6e-98 ykoE S ABC-type cobalt transport system, permease component
OICMKCED_02950 1e-306 P ABC transporter, ATP-binding protein
OICMKCED_02951 8.4e-134 ykoC P Cobalt transport protein
OICMKCED_02952 2.4e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OICMKCED_02953 1.5e-175 isp O Belongs to the peptidase S8 family
OICMKCED_02954 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OICMKCED_02955 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
OICMKCED_02956 1.4e-71 ohrB O Organic hydroperoxide resistance protein
OICMKCED_02957 4.4e-74 ohrR K COG1846 Transcriptional regulators
OICMKCED_02958 1.3e-70 ohrA O Organic hydroperoxide resistance protein
OICMKCED_02959 6.9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OICMKCED_02960 3.3e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OICMKCED_02961 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
OICMKCED_02962 7e-50 ykkD P Multidrug resistance protein
OICMKCED_02963 3.5e-55 ykkC P Multidrug resistance protein
OICMKCED_02964 1.1e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OICMKCED_02965 5.7e-97 ykkA S Protein of unknown function (DUF664)
OICMKCED_02966 2.7e-129 ykjA S Protein of unknown function (DUF421)
OICMKCED_02967 6.8e-223 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OICMKCED_02968 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
OICMKCED_02969 2e-160 ykgA E Amidinotransferase
OICMKCED_02970 1.4e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
OICMKCED_02971 2.2e-187 ykfD E Belongs to the ABC transporter superfamily
OICMKCED_02972 7.5e-166 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OICMKCED_02973 5.7e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OICMKCED_02974 2.4e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
OICMKCED_02976 0.0 dppE E ABC transporter substrate-binding protein
OICMKCED_02977 6.6e-187 dppD P Belongs to the ABC transporter superfamily
OICMKCED_02978 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OICMKCED_02979 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OICMKCED_02980 5.1e-153 dppA E D-aminopeptidase
OICMKCED_02981 4.5e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
OICMKCED_02982 8.4e-209 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OICMKCED_02984 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OICMKCED_02985 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OICMKCED_02986 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
OICMKCED_02987 1.2e-239 steT E amino acid
OICMKCED_02988 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
OICMKCED_02989 7.6e-175 pit P phosphate transporter
OICMKCED_02990 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
OICMKCED_02991 6.7e-23 spoIISB S Stage II sporulation protein SB
OICMKCED_02992 4e-159 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OICMKCED_02993 9.3e-40 xhlB S SPP1 phage holin
OICMKCED_02994 6.2e-39 xhlA S Haemolysin XhlA
OICMKCED_02995 7.5e-152 xepA
OICMKCED_02996 3.8e-23 xkdX
OICMKCED_02997 2.6e-55 xkdW S XkdW protein
OICMKCED_02998 1.5e-260
OICMKCED_02999 8.7e-41
OICMKCED_03000 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
OICMKCED_03001 1.1e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OICMKCED_03002 2.4e-69 xkdS S Protein of unknown function (DUF2634)
OICMKCED_03003 6.1e-39 xkdR S Protein of unknown function (DUF2577)
OICMKCED_03004 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
OICMKCED_03005 3.7e-122 xkdP S Lysin motif
OICMKCED_03006 0.0 xkdO L Transglycosylase SLT domain
OICMKCED_03007 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
OICMKCED_03008 6.1e-76 xkdM S Phage tail tube protein
OICMKCED_03009 2.5e-256 xkdK S Phage tail sheath C-terminal domain
OICMKCED_03010 1.9e-77 xkdJ
OICMKCED_03011 8.4e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
OICMKCED_03012 3.3e-64 yqbH S Domain of unknown function (DUF3599)
OICMKCED_03013 1.5e-62 yqbG S Protein of unknown function (DUF3199)
OICMKCED_03014 5.8e-169 xkdG S Phage capsid family
OICMKCED_03015 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
OICMKCED_03016 4.6e-285 yqbA S portal protein
OICMKCED_03017 1.2e-252 xtmB S phage terminase, large subunit
OICMKCED_03018 1.2e-138 xtmA L phage terminase small subunit
OICMKCED_03019 2.2e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OICMKCED_03020 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
OICMKCED_03023 9.2e-118 xkdC L Bacterial dnaA protein
OICMKCED_03024 2.3e-156 xkdB K sequence-specific DNA binding
OICMKCED_03026 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
OICMKCED_03027 1e-110 xkdA E IrrE N-terminal-like domain
OICMKCED_03028 4.4e-160 ydbD P Catalase
OICMKCED_03029 2.1e-111 yjqB S Pfam:DUF867
OICMKCED_03030 6.8e-60 yjqA S Bacterial PH domain
OICMKCED_03031 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
OICMKCED_03032 6.3e-41 S YCII-related domain
OICMKCED_03034 1e-212 S response regulator aspartate phosphatase
OICMKCED_03035 4e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
OICMKCED_03036 2.3e-78 yjoA S DinB family
OICMKCED_03037 7.4e-130 MA20_18170 S membrane transporter protein
OICMKCED_03038 3.5e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
OICMKCED_03039 8.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
OICMKCED_03040 2.3e-184 exuR K transcriptional
OICMKCED_03041 1.6e-225 exuT G Sugar (and other) transporter
OICMKCED_03042 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OICMKCED_03043 1.4e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
OICMKCED_03044 4.8e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
OICMKCED_03045 2.5e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
OICMKCED_03046 1.4e-248 yjmB G symporter YjmB
OICMKCED_03047 5.1e-278 uxaC 5.3.1.12 G glucuronate isomerase
OICMKCED_03048 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
OICMKCED_03049 7.1e-66 yjlC S Protein of unknown function (DUF1641)
OICMKCED_03050 4.9e-90 yjlB S Cupin domain
OICMKCED_03051 1.9e-175 yjlA EG Putative multidrug resistance efflux transporter
OICMKCED_03052 5.4e-133 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
OICMKCED_03053 1.9e-122 ybbM S transport system, permease component
OICMKCED_03054 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OICMKCED_03055 8.2e-30
OICMKCED_03056 1.6e-216 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OICMKCED_03057 2.2e-221 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
OICMKCED_03059 2.3e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
OICMKCED_03061 1.6e-94 yjgD S Protein of unknown function (DUF1641)
OICMKCED_03062 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
OICMKCED_03063 2e-103 yjgB S Domain of unknown function (DUF4309)
OICMKCED_03064 1.2e-45 T PhoQ Sensor
OICMKCED_03065 3.4e-166 yjfC O Predicted Zn-dependent protease (DUF2268)
OICMKCED_03066 2.3e-20 yjfB S Putative motility protein
OICMKCED_03067 3e-81 S Protein of unknown function (DUF2690)
OICMKCED_03068 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
OICMKCED_03070 7.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OICMKCED_03071 1e-48 yjdJ S Domain of unknown function (DUF4306)
OICMKCED_03072 4.2e-29 S Domain of unknown function (DUF4177)
OICMKCED_03073 1.4e-78 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OICMKCED_03075 1.3e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
OICMKCED_03076 6.5e-48 yjdF S Protein of unknown function (DUF2992)
OICMKCED_03077 4.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
OICMKCED_03078 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
OICMKCED_03079 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
OICMKCED_03080 6e-140 IQ Enoyl-(Acyl carrier protein) reductase
OICMKCED_03081 3.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
OICMKCED_03083 9e-19
OICMKCED_03084 1.9e-36
OICMKCED_03085 3.7e-30 KLT Protein tyrosine kinase
OICMKCED_03087 6.3e-220 yobL S Bacterial EndoU nuclease
OICMKCED_03088 1.7e-48
OICMKCED_03090 1.1e-212 yjcL S Protein of unknown function (DUF819)
OICMKCED_03091 2.9e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
OICMKCED_03092 9.4e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OICMKCED_03093 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OICMKCED_03094 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
OICMKCED_03095 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
OICMKCED_03096 3.3e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OICMKCED_03097 1.7e-38
OICMKCED_03098 0.0 yjcD 3.6.4.12 L DNA helicase
OICMKCED_03099 2.9e-38 spoVIF S Stage VI sporulation protein F
OICMKCED_03102 4.3e-56 yjcA S Protein of unknown function (DUF1360)
OICMKCED_03103 4.2e-49 cotV S Spore Coat Protein X and V domain
OICMKCED_03104 3e-32 cotW
OICMKCED_03105 6.4e-77 cotX S Spore Coat Protein X and V domain
OICMKCED_03106 3.4e-96 cotY S Spore coat protein Z
OICMKCED_03107 5.2e-83 cotZ S Spore coat protein
OICMKCED_03108 3e-50 yjbX S Spore coat protein
OICMKCED_03109 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
OICMKCED_03110 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OICMKCED_03111 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OICMKCED_03112 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
OICMKCED_03113 3e-30 thiS H thiamine diphosphate biosynthetic process
OICMKCED_03114 3.6e-218 thiO 1.4.3.19 E Glycine oxidase
OICMKCED_03115 1.4e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
OICMKCED_03116 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OICMKCED_03117 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
OICMKCED_03118 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
OICMKCED_03119 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OICMKCED_03120 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OICMKCED_03121 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
OICMKCED_03122 7.8e-61 yjbL S Belongs to the UPF0738 family
OICMKCED_03123 1e-99 yjbK S protein conserved in bacteria
OICMKCED_03124 8.5e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OICMKCED_03125 3.7e-72 yjbI S Bacterial-like globin
OICMKCED_03126 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OICMKCED_03127 1.8e-20
OICMKCED_03128 0.0 pepF E oligoendopeptidase F
OICMKCED_03129 8.3e-218 yjbF S Competence protein
OICMKCED_03130 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OICMKCED_03131 6e-112 yjbE P Integral membrane protein TerC family
OICMKCED_03132 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OICMKCED_03133 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OICMKCED_03134 1.2e-212 yjbB EGP Major Facilitator Superfamily
OICMKCED_03135 5.5e-172 oppF E Belongs to the ABC transporter superfamily
OICMKCED_03136 6.8e-198 oppD P Belongs to the ABC transporter superfamily
OICMKCED_03137 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OICMKCED_03138 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OICMKCED_03139 0.0 oppA E ABC transporter substrate-binding protein
OICMKCED_03140 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
OICMKCED_03141 5e-147 yjbA S Belongs to the UPF0736 family
OICMKCED_03142 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OICMKCED_03143 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OICMKCED_03144 1.4e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
OICMKCED_03145 6.5e-187 appF E Belongs to the ABC transporter superfamily
OICMKCED_03146 1.8e-184 appD P Belongs to the ABC transporter superfamily
OICMKCED_03147 7.8e-151 yjaZ O Zn-dependent protease
OICMKCED_03148 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OICMKCED_03149 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OICMKCED_03150 2.7e-22 yjzB
OICMKCED_03151 7.3e-26 comZ S ComZ
OICMKCED_03152 1.1e-183 med S Transcriptional activator protein med
OICMKCED_03153 1.8e-101 yjaV
OICMKCED_03154 6.2e-142 yjaU I carboxylic ester hydrolase activity
OICMKCED_03155 2.3e-16 yjzD S Protein of unknown function (DUF2929)
OICMKCED_03156 9.5e-28 yjzC S YjzC-like protein
OICMKCED_03157 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OICMKCED_03158 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
OICMKCED_03159 9.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OICMKCED_03160 2.7e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
OICMKCED_03161 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
OICMKCED_03162 5.9e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OICMKCED_03163 3.5e-199 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OICMKCED_03164 1.7e-88 norB G Major Facilitator Superfamily
OICMKCED_03165 4.7e-271 yitY C D-arabinono-1,4-lactone oxidase
OICMKCED_03166 1.5e-22 pilT S Proteolipid membrane potential modulator
OICMKCED_03167 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
OICMKCED_03168 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
OICMKCED_03169 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
OICMKCED_03171 1.2e-17 S Protein of unknown function (DUF3813)
OICMKCED_03172 1.7e-73 ipi S Intracellular proteinase inhibitor
OICMKCED_03173 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
OICMKCED_03174 2.7e-157 yitS S protein conserved in bacteria
OICMKCED_03175 1.1e-308 nprB 3.4.24.28 E Peptidase M4
OICMKCED_03176 1.4e-44 yitR S Domain of unknown function (DUF3784)
OICMKCED_03177 2.5e-93
OICMKCED_03178 4.5e-58 K Transcriptional regulator PadR-like family
OICMKCED_03179 1.5e-97 S Sporulation delaying protein SdpA
OICMKCED_03180 2.8e-171
OICMKCED_03181 8.5e-94
OICMKCED_03182 6.9e-161 cvfB S protein conserved in bacteria
OICMKCED_03183 8.6e-55 yajQ S Belongs to the UPF0234 family
OICMKCED_03184 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
OICMKCED_03185 4.6e-71 yjcF S Acetyltransferase (GNAT) domain
OICMKCED_03186 1.8e-156 yitH K Acetyltransferase (GNAT) domain
OICMKCED_03187 4e-229 yitG EGP Major facilitator Superfamily
OICMKCED_03188 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OICMKCED_03189 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OICMKCED_03190 1.9e-141 yitD 4.4.1.19 S synthase
OICMKCED_03191 1.1e-119 comB 3.1.3.71 H Belongs to the ComB family
OICMKCED_03192 2.1e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OICMKCED_03193 2.3e-231 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OICMKCED_03194 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
OICMKCED_03195 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OICMKCED_03196 6.8e-36 mcbG S Pentapeptide repeats (9 copies)
OICMKCED_03197 5.8e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OICMKCED_03198 1.4e-99 argO S Lysine exporter protein LysE YggA
OICMKCED_03199 7e-92 yisT S DinB family
OICMKCED_03200 5.2e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
OICMKCED_03201 6.9e-184 purR K helix_turn _helix lactose operon repressor
OICMKCED_03202 1.2e-160 yisR K Transcriptional regulator
OICMKCED_03203 1.5e-242 yisQ V Mate efflux family protein
OICMKCED_03204 1.7e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
OICMKCED_03205 6.4e-88 yizA S Damage-inducible protein DinB
OICMKCED_03206 0.0 asnO 6.3.5.4 E Asparagine synthase
OICMKCED_03207 1.3e-102 yisN S Protein of unknown function (DUF2777)
OICMKCED_03208 0.0 wprA O Belongs to the peptidase S8 family
OICMKCED_03209 6.6e-57 yisL S UPF0344 protein
OICMKCED_03210 1.3e-170 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
OICMKCED_03211 1.2e-171 cotH M Spore Coat
OICMKCED_03212 1.5e-22 yisI S Spo0E like sporulation regulatory protein
OICMKCED_03213 1.9e-33 gerPA S Spore germination protein
OICMKCED_03214 4e-34 gerPB S cell differentiation
OICMKCED_03215 1.8e-54 gerPC S Spore germination protein
OICMKCED_03216 6.3e-24 gerPD S Spore germination protein
OICMKCED_03217 3e-66 gerPE S Spore germination protein GerPE
OICMKCED_03218 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
OICMKCED_03219 1.1e-49 yisB V COG1403 Restriction endonuclease
OICMKCED_03220 0.0 sbcC L COG0419 ATPase involved in DNA repair
OICMKCED_03221 1.2e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
OICMKCED_03222 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
OICMKCED_03223 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
OICMKCED_03224 2.2e-78 yhjR S Rubrerythrin
OICMKCED_03225 9.5e-34 yhjQ C COG1145 Ferredoxin
OICMKCED_03226 0.0 S Sugar transport-related sRNA regulator N-term
OICMKCED_03227 4.2e-212 EGP Transmembrane secretion effector
OICMKCED_03228 4.2e-201 abrB S membrane
OICMKCED_03229 2.2e-187 yhjM 5.1.1.1 K Transcriptional regulator
OICMKCED_03230 6.3e-254 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
OICMKCED_03231 9e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
OICMKCED_03232 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
OICMKCED_03233 3.4e-214 glcP G Major Facilitator Superfamily
OICMKCED_03234 4.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
OICMKCED_03235 1.1e-281 yhjG CH FAD binding domain
OICMKCED_03236 1e-90 sipV 3.4.21.89 U Belongs to the peptidase S26 family
OICMKCED_03237 9.1e-110 yhjE S SNARE associated Golgi protein
OICMKCED_03238 2.5e-59 yhjD
OICMKCED_03239 6.9e-27 yhjC S Protein of unknown function (DUF3311)
OICMKCED_03240 2e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OICMKCED_03241 2.3e-41 yhjA S Excalibur calcium-binding domain
OICMKCED_03242 2.7e-15 IQ Enoyl-(Acyl carrier protein) reductase
OICMKCED_03243 8.5e-145 IQ Enoyl-(Acyl carrier protein) reductase
OICMKCED_03244 9.3e-109 comK K Competence transcription factor
OICMKCED_03245 1.3e-32 yhzC S IDEAL
OICMKCED_03246 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OICMKCED_03247 1e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
OICMKCED_03248 1.7e-182 hemAT NT chemotaxis protein
OICMKCED_03249 1.1e-90 bioY S BioY family
OICMKCED_03250 3.3e-272 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OICMKCED_03251 2.9e-196 vraB 2.3.1.9 I Belongs to the thiolase family
OICMKCED_03252 7.1e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
OICMKCED_03253 4.8e-158 yfmC M Periplasmic binding protein
OICMKCED_03254 7e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
OICMKCED_03255 8.1e-76 VY92_01935 K acetyltransferase
OICMKCED_03256 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
OICMKCED_03257 6.6e-240 yhfN 3.4.24.84 O Peptidase M48
OICMKCED_03258 1.9e-65 yhfM
OICMKCED_03259 2.7e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OICMKCED_03260 1.1e-110 yhfK GM NmrA-like family
OICMKCED_03261 4.9e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
OICMKCED_03262 5.2e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
OICMKCED_03263 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OICMKCED_03264 3.7e-72 3.4.13.21 S ASCH
OICMKCED_03265 3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
OICMKCED_03266 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
OICMKCED_03267 1.1e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OICMKCED_03268 3e-214 yhgE S YhgE Pip N-terminal domain protein
OICMKCED_03269 5.4e-101 yhgD K Transcriptional regulator
OICMKCED_03270 4.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OICMKCED_03271 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
OICMKCED_03272 4.1e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OICMKCED_03273 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OICMKCED_03274 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
OICMKCED_03275 1e-32 1.15.1.2 C Rubrerythrin
OICMKCED_03276 1.1e-245 yhfA C membrane
OICMKCED_03277 3.1e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OICMKCED_03278 5.3e-114 ecsC S EcsC protein family
OICMKCED_03279 5.4e-215 ecsB U ABC transporter
OICMKCED_03280 4.6e-137 ecsA V transporter (ATP-binding protein)
OICMKCED_03281 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
OICMKCED_03282 2.7e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OICMKCED_03283 3.1e-79 trpP S Tryptophan transporter TrpP
OICMKCED_03284 5.4e-21
OICMKCED_03285 7e-39 yhaH S YtxH-like protein
OICMKCED_03286 1e-113 hpr K Negative regulator of protease production and sporulation
OICMKCED_03287 1.3e-54 yhaI S Protein of unknown function (DUF1878)
OICMKCED_03288 1.5e-89 yhaK S Putative zincin peptidase
OICMKCED_03289 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OICMKCED_03290 1.6e-21 yhaL S Sporulation protein YhaL
OICMKCED_03291 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
OICMKCED_03292 0.0 yhaN L AAA domain
OICMKCED_03293 1.1e-223 yhaO L DNA repair exonuclease
OICMKCED_03294 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
OICMKCED_03295 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
OICMKCED_03296 2.4e-26 S YhzD-like protein
OICMKCED_03297 3.8e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
OICMKCED_03299 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
OICMKCED_03300 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
OICMKCED_03301 7.9e-293 hemZ H coproporphyrinogen III oxidase
OICMKCED_03302 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
OICMKCED_03303 1.2e-202 yhaZ L DNA alkylation repair enzyme
OICMKCED_03304 9.5e-48 yheA S Belongs to the UPF0342 family
OICMKCED_03305 4.5e-200 yheB S Belongs to the UPF0754 family
OICMKCED_03306 4.3e-216 yheC HJ YheC/D like ATP-grasp
OICMKCED_03307 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
OICMKCED_03308 1.3e-36 yheE S Family of unknown function (DUF5342)
OICMKCED_03309 6.3e-28 sspB S spore protein
OICMKCED_03310 1e-108 yheG GM NAD(P)H-binding
OICMKCED_03311 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
OICMKCED_03312 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
OICMKCED_03313 1.5e-83 nhaX T Belongs to the universal stress protein A family
OICMKCED_03314 2.9e-230 nhaC C Na H antiporter
OICMKCED_03315 3.4e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
OICMKCED_03316 3.8e-151 yheN G deacetylase
OICMKCED_03317 2.6e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
OICMKCED_03318 9.9e-184 yhdY M Mechanosensitive ion channel
OICMKCED_03320 1.8e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OICMKCED_03321 2.1e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OICMKCED_03322 6.2e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OICMKCED_03323 1.4e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
OICMKCED_03324 2.6e-222 yhdR 2.6.1.1 E Aminotransferase
OICMKCED_03325 4.2e-74 cueR K transcriptional
OICMKCED_03326 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OICMKCED_03327 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OICMKCED_03328 1.5e-191 yhdN C Aldo keto reductase
OICMKCED_03329 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
OICMKCED_03330 2.5e-200 yhdL S Sigma factor regulator N-terminal
OICMKCED_03331 8.1e-45 yhdK S Sigma-M inhibitor protein
OICMKCED_03332 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OICMKCED_03333 1.1e-189 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OICMKCED_03334 1.1e-240 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OICMKCED_03335 3.4e-250 yhdG E amino acid
OICMKCED_03336 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OICMKCED_03337 1.2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
OICMKCED_03338 3.8e-162 citR K Transcriptional regulator
OICMKCED_03339 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OICMKCED_03340 1.6e-255 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
OICMKCED_03341 6.3e-276 ycgB S Stage V sporulation protein R
OICMKCED_03342 1.5e-238 ygxB M Conserved TM helix
OICMKCED_03343 1e-75 nsrR K Transcriptional regulator
OICMKCED_03344 8.7e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OICMKCED_03345 4.8e-54 yhdC S Protein of unknown function (DUF3889)
OICMKCED_03346 1.2e-38 yhdB S YhdB-like protein
OICMKCED_03347 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
OICMKCED_03348 2e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OICMKCED_03349 2.7e-213 yhcY 2.7.13.3 T Histidine kinase
OICMKCED_03350 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
OICMKCED_03351 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OICMKCED_03352 1.3e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OICMKCED_03353 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
OICMKCED_03354 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OICMKCED_03355 1.6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OICMKCED_03356 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OICMKCED_03357 1.3e-119 yhcW 5.4.2.6 S hydrolase
OICMKCED_03358 9.9e-68 yhcV S COG0517 FOG CBS domain
OICMKCED_03359 2.1e-67 yhcU S Family of unknown function (DUF5365)
OICMKCED_03360 7.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OICMKCED_03361 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
OICMKCED_03362 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
OICMKCED_03363 4.4e-99 yhcQ M Spore coat protein
OICMKCED_03364 1.3e-166 yhcP
OICMKCED_03365 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OICMKCED_03366 1.1e-40 yhcM
OICMKCED_03367 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OICMKCED_03368 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
OICMKCED_03369 4.4e-152 metQ M Belongs to the nlpA lipoprotein family
OICMKCED_03370 1e-30 cspB K Cold-shock protein
OICMKCED_03371 5.6e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OICMKCED_03372 7.7e-166 yhcH V ABC transporter, ATP-binding protein
OICMKCED_03373 4e-122 yhcG V ABC transporter, ATP-binding protein
OICMKCED_03374 1.9e-59 yhcF K Transcriptional regulator
OICMKCED_03375 2e-55
OICMKCED_03376 2.8e-37 yhcC
OICMKCED_03377 1.4e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
OICMKCED_03378 3.1e-271 yhcA EGP Major facilitator Superfamily
OICMKCED_03379 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
OICMKCED_03380 2.2e-76 yhbI K DNA-binding transcription factor activity
OICMKCED_03381 2.5e-225 yhbH S Belongs to the UPF0229 family
OICMKCED_03382 0.0 prkA T Ser protein kinase
OICMKCED_03383 9.4e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
OICMKCED_03384 1e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
OICMKCED_03385 2.7e-109 yhbD K Protein of unknown function (DUF4004)
OICMKCED_03386 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OICMKCED_03387 1.8e-175 yhbB S Putative amidase domain
OICMKCED_03388 1.7e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OICMKCED_03389 3.9e-113 yhzB S B3/4 domain
OICMKCED_03391 4.4e-29 K Transcriptional regulator
OICMKCED_03392 7.7e-77 ygaO
OICMKCED_03393 1.5e-40 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OICMKCED_03395 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
OICMKCED_03396 3.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OICMKCED_03397 1.8e-168 ssuA M Sulfonate ABC transporter
OICMKCED_03398 2.2e-137 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
OICMKCED_03399 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OICMKCED_03401 8.4e-262 ygaK C Berberine and berberine like
OICMKCED_03402 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OICMKCED_03403 1.3e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
OICMKCED_03404 3e-27
OICMKCED_03405 2.7e-143 spo0M S COG4326 Sporulation control protein
OICMKCED_03409 2e-08
OICMKCED_03417 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
OICMKCED_03418 7.1e-86 ybbJ J acetyltransferase
OICMKCED_03419 6.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OICMKCED_03420 2.1e-149 ybbH K transcriptional
OICMKCED_03421 2.2e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OICMKCED_03422 6.6e-251 yfeW 3.4.16.4 V Belongs to the UPF0214 family
OICMKCED_03423 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
OICMKCED_03424 5.4e-239 ybbC 3.2.1.52 S protein conserved in bacteria
OICMKCED_03425 2.9e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
OICMKCED_03426 2.7e-166 feuA P Iron-uptake system-binding protein
OICMKCED_03427 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OICMKCED_03428 6.7e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OICMKCED_03429 2.2e-142 ybbA S Putative esterase
OICMKCED_03430 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
OICMKCED_03431 1.5e-248 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
OICMKCED_03437 1.5e-166 ygxA S Nucleotidyltransferase-like
OICMKCED_03438 2.8e-55 ygzB S UPF0295 protein
OICMKCED_03439 4e-80 perR P Belongs to the Fur family
OICMKCED_03440 6.3e-87 bcp 1.11.1.15 O Peroxiredoxin
OICMKCED_03441 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OICMKCED_03442 1.5e-179 ygaE S Membrane
OICMKCED_03443 1.8e-301 ygaD V ABC transporter
OICMKCED_03444 1.3e-104 ygaC J Belongs to the UPF0374 family
OICMKCED_03445 1.5e-37 ygaB S YgaB-like protein
OICMKCED_03446 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
OICMKCED_03447 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OICMKCED_03448 2.6e-35 yfhS
OICMKCED_03449 7.8e-212 mutY L A G-specific
OICMKCED_03450 5.5e-186 yfhP S membrane-bound metal-dependent
OICMKCED_03451 0.0 yfhO S Bacterial membrane protein YfhO
OICMKCED_03452 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OICMKCED_03453 3.1e-169 yfhM S Alpha beta hydrolase
OICMKCED_03454 3.5e-51 yfhL S SdpI/YhfL protein family
OICMKCED_03455 2.1e-88 batE T Bacterial SH3 domain homologues
OICMKCED_03456 1.3e-44 yfhJ S WVELL protein
OICMKCED_03457 9e-19 sspK S reproduction
OICMKCED_03458 2.5e-209 yfhI EGP Major facilitator Superfamily
OICMKCED_03459 9.7e-52 yfhH S Protein of unknown function (DUF1811)
OICMKCED_03460 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
OICMKCED_03461 6e-171 yfhF S nucleoside-diphosphate sugar epimerase
OICMKCED_03463 2.1e-25 yfhD S YfhD-like protein
OICMKCED_03464 3.9e-107 yfhC C nitroreductase
OICMKCED_03465 1.6e-165 yfhB 5.3.3.17 S PhzF family
OICMKCED_03466 2.9e-169 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OICMKCED_03467 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OICMKCED_03468 3.7e-166 yfiY P ABC transporter substrate-binding protein
OICMKCED_03469 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OICMKCED_03470 2.2e-79 yfiV K transcriptional
OICMKCED_03471 3.4e-283 yfiU EGP Major facilitator Superfamily
OICMKCED_03472 3.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
OICMKCED_03473 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OICMKCED_03474 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OICMKCED_03475 4.1e-98 padR K transcriptional
OICMKCED_03476 2.9e-202 V COG0842 ABC-type multidrug transport system, permease component
OICMKCED_03477 1.5e-206 V ABC-2 family transporter protein
OICMKCED_03478 8.9e-170 V ABC transporter, ATP-binding protein
OICMKCED_03479 5.4e-113 KT LuxR family transcriptional regulator
OICMKCED_03480 3.4e-211 yxjM T Histidine kinase
OICMKCED_03482 2.8e-162 yfiE 1.13.11.2 S glyoxalase
OICMKCED_03483 6.4e-64 mhqP S DoxX
OICMKCED_03484 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
OICMKCED_03485 3.5e-305 yfiB3 V ABC transporter
OICMKCED_03486 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OICMKCED_03487 2.7e-140 glvR K Helix-turn-helix domain, rpiR family
OICMKCED_03488 1.4e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OICMKCED_03489 1.7e-43 yfjA S Belongs to the WXG100 family
OICMKCED_03490 9.6e-172 yfjB
OICMKCED_03491 2.3e-123 yfjC
OICMKCED_03492 1.4e-85 S Family of unknown function (DUF5381)
OICMKCED_03493 1.2e-55 yfjF S UPF0060 membrane protein
OICMKCED_03494 1.2e-25 sspH S Belongs to the SspH family
OICMKCED_03495 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
OICMKCED_03496 2.3e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OICMKCED_03497 2.4e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OICMKCED_03498 2.1e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OICMKCED_03499 3.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OICMKCED_03500 3.4e-82 yfjM S Psort location Cytoplasmic, score
OICMKCED_03501 4.2e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OICMKCED_03502 6.7e-44 S YfzA-like protein
OICMKCED_03503 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OICMKCED_03504 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OICMKCED_03505 1.7e-184 corA P Mediates influx of magnesium ions
OICMKCED_03506 1.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
OICMKCED_03507 1.7e-153 pdaA G deacetylase
OICMKCED_03508 1.1e-26 yfjT
OICMKCED_03509 5.4e-222 yfkA S YfkB-like domain
OICMKCED_03510 7.8e-149 yfkC M Mechanosensitive ion channel
OICMKCED_03511 1.2e-146 yfkD S YfkD-like protein
OICMKCED_03512 6.1e-183 cax P COG0387 Ca2 H antiporter
OICMKCED_03513 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
OICMKCED_03514 5e-08
OICMKCED_03515 9.7e-144 yihY S Belongs to the UPF0761 family
OICMKCED_03516 2.4e-50 yfkI S gas vesicle protein
OICMKCED_03517 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OICMKCED_03518 1.3e-28 yfkK S Belongs to the UPF0435 family
OICMKCED_03519 5.8e-206 ydiM EGP Major facilitator Superfamily
OICMKCED_03520 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
OICMKCED_03521 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
OICMKCED_03522 1.1e-124 yfkO C nitroreductase
OICMKCED_03523 1.8e-133 treR K transcriptional
OICMKCED_03524 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
OICMKCED_03525 2.5e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OICMKCED_03526 6.5e-27 yfkQ EG Spore germination protein
OICMKCED_03527 3.2e-234 yfkQ EG Spore germination protein
OICMKCED_03528 1.1e-206 yfkR S spore germination
OICMKCED_03530 2.1e-191 E Spore germination protein
OICMKCED_03531 2.2e-252 agcS_1 E Sodium alanine symporter
OICMKCED_03532 6e-67 yhdN S Domain of unknown function (DUF1992)
OICMKCED_03533 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OICMKCED_03534 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
OICMKCED_03535 4.2e-138 map 3.4.11.18 E Methionine aminopeptidase
OICMKCED_03536 5.3e-50 yflH S Protein of unknown function (DUF3243)
OICMKCED_03537 1.6e-18 yflI
OICMKCED_03538 4e-18 yflJ S Protein of unknown function (DUF2639)
OICMKCED_03539 9e-124 yflK S protein conserved in bacteria
OICMKCED_03540 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
OICMKCED_03541 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OICMKCED_03542 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
OICMKCED_03543 1.9e-226 citM C Citrate transporter
OICMKCED_03544 2.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
OICMKCED_03545 8.9e-119 citT T response regulator
OICMKCED_03546 3e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OICMKCED_03547 2.5e-235 yflS P Sodium:sulfate symporter transmembrane region
OICMKCED_03548 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
OICMKCED_03549 7.6e-58 yflT S Heat induced stress protein YflT
OICMKCED_03550 8.5e-24 S Protein of unknown function (DUF3212)
OICMKCED_03551 3.9e-165 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
OICMKCED_03552 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OICMKCED_03553 2e-167 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OICMKCED_03554 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
OICMKCED_03555 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
OICMKCED_03556 7.7e-214 G Major Facilitator Superfamily
OICMKCED_03557 9.4e-189 yfmJ S N-terminal domain of oxidoreductase
OICMKCED_03558 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
OICMKCED_03559 2.9e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
OICMKCED_03560 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OICMKCED_03561 1.5e-209 yfmO EGP Major facilitator Superfamily
OICMKCED_03562 3.1e-69 yfmP K transcriptional
OICMKCED_03563 1.2e-74 yfmQ S Uncharacterised protein from bacillus cereus group
OICMKCED_03564 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OICMKCED_03565 1.1e-113 yfmS NT chemotaxis protein
OICMKCED_03566 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OICMKCED_03567 6.4e-241 yfnA E amino acid
OICMKCED_03568 2.3e-133 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
OICMKCED_03569 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
OICMKCED_03570 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
OICMKCED_03571 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
OICMKCED_03572 1.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
OICMKCED_03573 2.4e-172 yfnG 4.2.1.45 M dehydratase
OICMKCED_03574 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
OICMKCED_03575 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OICMKCED_03576 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OICMKCED_03577 3.7e-196 yetN S Protein of unknown function (DUF3900)
OICMKCED_03578 1.7e-133 M Membrane
OICMKCED_03579 6.8e-209 yetM CH FAD binding domain
OICMKCED_03580 1.4e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
OICMKCED_03581 4.5e-104 yetJ S Belongs to the BI1 family
OICMKCED_03582 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
OICMKCED_03583 4.9e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OICMKCED_03584 2.6e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OICMKCED_03585 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
OICMKCED_03586 8.8e-122 yetF S membrane
OICMKCED_03587 1.2e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
OICMKCED_03588 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
OICMKCED_03589 5.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
OICMKCED_03590 4e-289 lplA G Bacterial extracellular solute-binding protein
OICMKCED_03591 0.0 yetA
OICMKCED_03592 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
OICMKCED_03593 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
OICMKCED_03594 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
OICMKCED_03595 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
OICMKCED_03596 6.3e-111 yesV S Protein of unknown function, DUF624
OICMKCED_03597 3.4e-131 yesU S Domain of unknown function (DUF1961)
OICMKCED_03598 3.8e-133 E GDSL-like Lipase/Acylhydrolase
OICMKCED_03599 0.0 yesS K Transcriptional regulator
OICMKCED_03600 2.7e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
OICMKCED_03601 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
OICMKCED_03602 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
OICMKCED_03603 8e-246 yesO G Bacterial extracellular solute-binding protein
OICMKCED_03604 8e-202 yesN K helix_turn_helix, arabinose operon control protein
OICMKCED_03605 0.0 yesM 2.7.13.3 T Histidine kinase
OICMKCED_03606 1.3e-100 yesL S Protein of unknown function, DUF624
OICMKCED_03608 8.7e-101 yesJ K Acetyltransferase (GNAT) family
OICMKCED_03609 5.2e-104 cotJC P Spore Coat
OICMKCED_03610 1.5e-45 cotJB S CotJB protein
OICMKCED_03611 3.4e-44 cotJA S Spore coat associated protein JA (CotJA)
OICMKCED_03612 1.1e-150 yesF GM NAD(P)H-binding
OICMKCED_03613 9.7e-82 yesE S SnoaL-like domain
OICMKCED_03614 3.6e-100 dhaR3 K Transcriptional regulator
OICMKCED_03616 2.7e-126 yeeN K transcriptional regulatory protein
OICMKCED_03618 1.3e-210 S Tetratricopeptide repeat
OICMKCED_03619 1.1e-162 3.4.24.40 CO amine dehydrogenase activity
OICMKCED_03620 8.7e-101 L endonuclease activity
OICMKCED_03622 3.6e-186 yobL S Bacterial EndoU nuclease
OICMKCED_03623 8.7e-42 S Immunity protein 22
OICMKCED_03624 3.4e-99 S response regulator aspartate phosphatase
OICMKCED_03626 5.7e-92 V Restriction endonuclease
OICMKCED_03627 1.7e-113
OICMKCED_03628 6.8e-45 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
OICMKCED_03629 3.3e-154 haeIIIM 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
OICMKCED_03630 4.9e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OICMKCED_03631 5.1e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OICMKCED_03632 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OICMKCED_03633 1.3e-146 yerO K Transcriptional regulator
OICMKCED_03634 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OICMKCED_03635 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OICMKCED_03636 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OICMKCED_03637 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OICMKCED_03638 1.6e-123 sapB S MgtC SapB transporter
OICMKCED_03639 3.5e-196 yerI S homoserine kinase type II (protein kinase fold)
OICMKCED_03640 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
OICMKCED_03641 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OICMKCED_03642 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OICMKCED_03643 8.4e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OICMKCED_03645 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
OICMKCED_03646 4.8e-51 yerC S protein conserved in bacteria
OICMKCED_03647 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
OICMKCED_03648 0.0 yerA 3.5.4.2 F adenine deaminase
OICMKCED_03649 2.7e-27 S Protein of unknown function (DUF2892)
OICMKCED_03650 1.9e-231 yjeH E Amino acid permease
OICMKCED_03651 1.1e-71 K helix_turn_helix ASNC type
OICMKCED_03652 1e-232 purD 6.3.4.13 F Belongs to the GARS family
OICMKCED_03653 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
OICMKCED_03654 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OICMKCED_03655 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
OICMKCED_03656 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OICMKCED_03657 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OICMKCED_03658 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OICMKCED_03659 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OICMKCED_03660 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
OICMKCED_03661 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OICMKCED_03662 9.4e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OICMKCED_03663 3.7e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OICMKCED_03664 8e-28 yebG S NETI protein
OICMKCED_03665 8.9e-93 yebE S UPF0316 protein
OICMKCED_03667 2.3e-118 yebC M Membrane
OICMKCED_03668 5.1e-211 pbuG S permease
OICMKCED_03669 1.7e-252 S Domain of unknown function (DUF4179)
OICMKCED_03670 1e-85 K Belongs to the sigma-70 factor family. ECF subfamily
OICMKCED_03671 7.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OICMKCED_03672 0.0 yebA E COG1305 Transglutaminase-like enzymes
OICMKCED_03673 3.6e-224 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
OICMKCED_03674 1.7e-176 yeaC S COG0714 MoxR-like ATPases
OICMKCED_03675 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OICMKCED_03676 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
OICMKCED_03677 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
OICMKCED_03678 8e-177 yeaA S Protein of unknown function (DUF4003)
OICMKCED_03679 2.8e-159 ydjP I Alpha/beta hydrolase family
OICMKCED_03680 1.4e-34 ydjO S Cold-inducible protein YdjO
OICMKCED_03682 1.6e-151 ydjN U Involved in the tonB-independent uptake of proteins
OICMKCED_03683 4.5e-64 ydjM M Lytic transglycolase
OICMKCED_03684 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
OICMKCED_03685 2.7e-258 iolT EGP Major facilitator Superfamily
OICMKCED_03686 4.7e-196 S Ion transport 2 domain protein
OICMKCED_03687 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
OICMKCED_03688 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
OICMKCED_03689 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OICMKCED_03690 5.6e-113 pspA KT Phage shock protein A
OICMKCED_03691 7.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
OICMKCED_03692 6.7e-254 gutA G MFS/sugar transport protein
OICMKCED_03693 8.5e-201 gutB 1.1.1.14 E Dehydrogenase
OICMKCED_03694 0.0 K NB-ARC domain
OICMKCED_03695 6e-153 ydjC S Abhydrolase domain containing 18
OICMKCED_03696 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OICMKCED_03697 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OICMKCED_03698 7.9e-129 ydiL S CAAX protease self-immunity
OICMKCED_03699 2.9e-27 ydiK S Domain of unknown function (DUF4305)
OICMKCED_03700 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OICMKCED_03701 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OICMKCED_03702 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OICMKCED_03703 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
OICMKCED_03704 0.0 ydiF S ABC transporter
OICMKCED_03705 3.9e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OICMKCED_03706 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
OICMKCED_03707 2.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
OICMKCED_03708 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
OICMKCED_03709 6e-177 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OICMKCED_03713 7.8e-08
OICMKCED_03714 7.8e-08
OICMKCED_03718 2.3e-156 ydhU P Catalase
OICMKCED_03719 2.9e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
OICMKCED_03720 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
OICMKCED_03721 2.2e-165 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
OICMKCED_03722 1.1e-132 ydhQ K UTRA
OICMKCED_03723 5.8e-282 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OICMKCED_03724 1.7e-238 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OICMKCED_03725 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
OICMKCED_03726 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
OICMKCED_03727 1.3e-199 pbuE EGP Major facilitator Superfamily
OICMKCED_03728 2.8e-97 ydhK M Protein of unknown function (DUF1541)
OICMKCED_03729 1.1e-178 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
OICMKCED_03730 1.9e-83 K Acetyltransferase (GNAT) domain
OICMKCED_03732 8.7e-68 frataxin S Domain of unknown function (DU1801)
OICMKCED_03733 2.6e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
OICMKCED_03734 1.9e-124
OICMKCED_03735 1.6e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OICMKCED_03736 1.1e-242 ydhD M Glycosyl hydrolase
OICMKCED_03737 6.5e-122 ydhC K FCD
OICMKCED_03738 3.5e-121 ydhB S membrane transporter protein
OICMKCED_03739 2.2e-208 tcaB EGP Major facilitator Superfamily
OICMKCED_03740 7.1e-69 ydgJ K Winged helix DNA-binding domain
OICMKCED_03741 8.8e-113 drgA C nitroreductase
OICMKCED_03742 0.0 ydgH S drug exporters of the RND superfamily
OICMKCED_03743 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
OICMKCED_03744 1.1e-89 dinB S DinB family
OICMKCED_03745 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
OICMKCED_03746 1e-301 expZ S ABC transporter
OICMKCED_03747 4.7e-52 yycN 2.3.1.128 K Acetyltransferase
OICMKCED_03748 9e-51 S DoxX-like family
OICMKCED_03749 2.2e-97 K Bacterial regulatory proteins, tetR family
OICMKCED_03750 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
OICMKCED_03751 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
OICMKCED_03752 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
OICMKCED_03753 9e-122 ydfS S Protein of unknown function (DUF421)
OICMKCED_03754 4.4e-118 ydfR S Protein of unknown function (DUF421)
OICMKCED_03756 6.3e-29
OICMKCED_03757 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
OICMKCED_03758 1.6e-55 traF CO Thioredoxin
OICMKCED_03759 8.8e-63 mhqP S DoxX
OICMKCED_03760 1.7e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
OICMKCED_03761 4e-110 ydfN C nitroreductase
OICMKCED_03762 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OICMKCED_03763 1.5e-65 K Bacterial transcription activator, effector binding domain
OICMKCED_03764 7e-56 K Bacterial transcription activator, effector binding domain
OICMKCED_03765 8.5e-117 S Protein of unknown function (DUF554)
OICMKCED_03766 3.1e-175 S Alpha/beta hydrolase family
OICMKCED_03767 0.0 ydfJ S drug exporters of the RND superfamily
OICMKCED_03768 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OICMKCED_03769 7.7e-179 ydfH 2.7.13.3 T Histidine kinase
OICMKCED_03770 3.4e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OICMKCED_03771 3.9e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
OICMKCED_03772 1.4e-115 ydfE S Flavin reductase like domain
OICMKCED_03773 2.3e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OICMKCED_03774 1.6e-158 ydfC EG EamA-like transporter family
OICMKCED_03775 1.8e-144 ydfB J GNAT acetyltransferase
OICMKCED_03776 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OICMKCED_03777 2.8e-57 arsR K transcriptional
OICMKCED_03778 3.2e-104 ydeS K Transcriptional regulator
OICMKCED_03779 9.6e-185 ydeR EGP Major facilitator Superfamily
OICMKCED_03780 2.1e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OICMKCED_03781 1.2e-55 K HxlR-like helix-turn-helix
OICMKCED_03782 2.5e-104 ydeN S Serine hydrolase
OICMKCED_03783 7.1e-74 maoC I N-terminal half of MaoC dehydratase
OICMKCED_03784 6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OICMKCED_03785 1.3e-151 ydeK EG -transporter
OICMKCED_03786 3.4e-84 K Transcriptional regulator C-terminal region
OICMKCED_03787 1.8e-14 ptsH G PTS HPr component phosphorylation site
OICMKCED_03788 3.8e-103
OICMKCED_03789 3.9e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
OICMKCED_03790 1.4e-44 ydeH
OICMKCED_03791 1.2e-217 ydeG EGP Major facilitator superfamily
OICMKCED_03792 2.4e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OICMKCED_03793 3.1e-164 ydeE K AraC family transcriptional regulator
OICMKCED_03794 8.3e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OICMKCED_03795 2e-163 rhaS5 K AraC-like ligand binding domain
OICMKCED_03796 3.3e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OICMKCED_03797 2.3e-78 carD K Transcription factor
OICMKCED_03798 8.7e-30 cspL K Cold shock
OICMKCED_03799 3.8e-190 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
OICMKCED_03800 9.6e-40
OICMKCED_03801 3.4e-33 K Helix-turn-helix XRE-family like proteins
OICMKCED_03802 5.2e-139 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OICMKCED_03803 1.1e-44
OICMKCED_03804 3.8e-75 rimJ2 J Acetyltransferase (GNAT) domain
OICMKCED_03812 8.9e-83 ydcK S Belongs to the SprT family
OICMKCED_03813 0.0 yhgF K COG2183 Transcriptional accessory protein
OICMKCED_03814 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
OICMKCED_03815 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OICMKCED_03816 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
OICMKCED_03817 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
OICMKCED_03818 7.1e-189 rsbU 3.1.3.3 KT phosphatase
OICMKCED_03819 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
OICMKCED_03820 1.5e-56 rsbS T antagonist
OICMKCED_03821 1.3e-143 rsbR T Positive regulator of sigma-B
OICMKCED_03822 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
OICMKCED_03823 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
OICMKCED_03824 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OICMKCED_03825 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
OICMKCED_03826 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OICMKCED_03827 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
OICMKCED_03828 2.9e-263 ydbT S Membrane
OICMKCED_03829 2.1e-82 ydbS S Bacterial PH domain
OICMKCED_03830 2e-248 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OICMKCED_03831 3.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OICMKCED_03832 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OICMKCED_03833 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OICMKCED_03834 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OICMKCED_03835 1.7e-07 S Fur-regulated basic protein A
OICMKCED_03836 1.1e-18 S Fur-regulated basic protein B
OICMKCED_03837 1.5e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
OICMKCED_03838 2.7e-52 ydbL
OICMKCED_03839 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OICMKCED_03840 1.3e-168 ydbJ V ABC transporter, ATP-binding protein
OICMKCED_03841 1.4e-179 ydbI S AI-2E family transporter
OICMKCED_03842 1.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OICMKCED_03843 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
OICMKCED_03844 1.3e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OICMKCED_03845 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
OICMKCED_03846 3.5e-154 ydbD P Catalase
OICMKCED_03847 1.3e-60 ydbC S Domain of unknown function (DUF4937
OICMKCED_03848 1.5e-55 ydbB G Cupin domain
OICMKCED_03850 3.2e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
OICMKCED_03851 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
OICMKCED_03853 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
OICMKCED_03854 9.4e-40
OICMKCED_03855 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
OICMKCED_03856 1.1e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
OICMKCED_03857 0.0 ydaO E amino acid
OICMKCED_03858 0.0 ydaN S Bacterial cellulose synthase subunit
OICMKCED_03859 4.5e-233 ydaM M Glycosyl transferase family group 2
OICMKCED_03860 6.2e-246 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
OICMKCED_03861 4e-44 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
OICMKCED_03862 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
OICMKCED_03863 1.2e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
OICMKCED_03864 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OICMKCED_03865 2.5e-74 lrpC K Transcriptional regulator
OICMKCED_03866 3.3e-46 ydzA EGP Major facilitator Superfamily
OICMKCED_03867 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
OICMKCED_03868 6.8e-77 ydaG 1.4.3.5 S general stress protein
OICMKCED_03869 6.1e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OICMKCED_03870 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
OICMKCED_03871 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OICMKCED_03872 1.7e-97 ydaC Q Methyltransferase domain
OICMKCED_03873 1.3e-292 ydaB IQ acyl-CoA ligase
OICMKCED_03874 0.0 mtlR K transcriptional regulator, MtlR
OICMKCED_03875 8.3e-173 ydhF S Oxidoreductase
OICMKCED_03876 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
OICMKCED_03877 1.4e-49 yczJ S biosynthesis
OICMKCED_03879 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
OICMKCED_03880 1.2e-132 kipR K Transcriptional regulator
OICMKCED_03881 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
OICMKCED_03882 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
OICMKCED_03883 4.8e-148 ycsI S Belongs to the D-glutamate cyclase family
OICMKCED_03884 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
OICMKCED_03885 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
OICMKCED_03886 3e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OICMKCED_03888 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
OICMKCED_03889 1.5e-109 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
OICMKCED_03890 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OICMKCED_03891 9.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OICMKCED_03892 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
OICMKCED_03893 9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
OICMKCED_03894 7.5e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
OICMKCED_03895 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
OICMKCED_03896 7.3e-56
OICMKCED_03897 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
OICMKCED_03898 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
OICMKCED_03899 1.3e-100 ycnI S protein conserved in bacteria
OICMKCED_03900 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OICMKCED_03901 6.1e-149 glcU U Glucose uptake
OICMKCED_03902 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OICMKCED_03903 3.7e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OICMKCED_03904 1.1e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OICMKCED_03905 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
OICMKCED_03906 1.6e-45 ycnE S Monooxygenase
OICMKCED_03907 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
OICMKCED_03908 5.5e-153 ycnC K Transcriptional regulator
OICMKCED_03909 5.9e-250 ycnB EGP Major facilitator Superfamily
OICMKCED_03910 1.2e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
OICMKCED_03911 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
OICMKCED_03912 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OICMKCED_03913 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OICMKCED_03914 8.3e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
OICMKCED_03917 2e-70 S aspartate phosphatase
OICMKCED_03918 1.5e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
OICMKCED_03919 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OICMKCED_03920 1.5e-203 yclI V ABC transporter (permease) YclI
OICMKCED_03921 1.9e-121 yclH P ABC transporter
OICMKCED_03922 9.9e-200 gerKB F Spore germination protein
OICMKCED_03923 1.3e-232 gerKC S spore germination
OICMKCED_03924 1.5e-281 gerKA EG Spore germination protein
OICMKCED_03926 2.7e-308 yclG M Pectate lyase superfamily protein
OICMKCED_03927 5.2e-265 dtpT E amino acid peptide transporter
OICMKCED_03928 2.2e-159 yclE 3.4.11.5 S Alpha beta hydrolase
OICMKCED_03929 2.5e-80 yclD
OICMKCED_03930 4e-39 bsdD 4.1.1.61 S response to toxic substance
OICMKCED_03931 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
OICMKCED_03932 7.6e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
OICMKCED_03933 1.9e-161 bsdA K LysR substrate binding domain
OICMKCED_03934 3.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
OICMKCED_03935 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
OICMKCED_03936 4.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OICMKCED_03937 1.7e-114 yczE S membrane
OICMKCED_03938 2.9e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
OICMKCED_03939 2.6e-236 ycxD K GntR family transcriptional regulator
OICMKCED_03940 2.9e-160 ycxC EG EamA-like transporter family
OICMKCED_03941 6.9e-85 S YcxB-like protein
OICMKCED_03942 2e-225 EGP Major Facilitator Superfamily
OICMKCED_03943 5.7e-140 srfAD Q thioesterase
OICMKCED_03944 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
OICMKCED_03945 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OICMKCED_03946 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OICMKCED_03947 1.3e-240 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OICMKCED_03948 1.3e-63 hxlR K transcriptional
OICMKCED_03949 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
OICMKCED_03950 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
OICMKCED_03951 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
OICMKCED_03952 1.2e-71 nucA M Deoxyribonuclease NucA/NucB
OICMKCED_03953 6.5e-69 nin S Competence protein J (ComJ)
OICMKCED_03954 2.8e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OICMKCED_03955 7.8e-52 yckD S Protein of unknown function (DUF2680)
OICMKCED_03956 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
OICMKCED_03957 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
OICMKCED_03958 4.1e-228 yciC S GTPases (G3E family)
OICMKCED_03959 6.8e-101 yciB M ErfK YbiS YcfS YnhG
OICMKCED_03960 1.6e-168 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
OICMKCED_03961 1.7e-221 nasA P COG2223 Nitrate nitrite transporter
OICMKCED_03962 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
OICMKCED_03963 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OICMKCED_03964 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OICMKCED_03965 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
OICMKCED_03966 5.8e-277 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OICMKCED_03967 4.9e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
OICMKCED_03968 7.7e-160 I alpha/beta hydrolase fold
OICMKCED_03969 2.7e-139 ycgR S permeases
OICMKCED_03970 1.4e-145 ycgQ S membrane
OICMKCED_03971 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
OICMKCED_03972 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OICMKCED_03973 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OICMKCED_03974 5.1e-170 ycgM E Proline dehydrogenase
OICMKCED_03975 4.1e-144 ycgL S Predicted nucleotidyltransferase
OICMKCED_03976 9.4e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
OICMKCED_03977 9.6e-175 oxyR3 K LysR substrate binding domain
OICMKCED_03978 2.4e-144 yafE Q ubiE/COQ5 methyltransferase family
OICMKCED_03979 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OICMKCED_03981 2.1e-108 tmrB S AAA domain
OICMKCED_03982 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OICMKCED_03983 2.4e-112 ycgI S Domain of unknown function (DUF1989)
OICMKCED_03984 2.1e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
OICMKCED_03985 1.2e-151 yqcI S YqcI/YcgG family
OICMKCED_03986 6.8e-113 ycgF E Lysine exporter protein LysE YggA
OICMKCED_03987 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
OICMKCED_03988 6.2e-269 mdr EGP Major facilitator Superfamily
OICMKCED_03989 6.5e-293 lctP C L-lactate permease
OICMKCED_03990 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OICMKCED_03991 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
OICMKCED_03992 1.1e-98 ycgB
OICMKCED_03993 8.7e-257 ycgA S Membrane
OICMKCED_03994 1.1e-217 amhX S amidohydrolase
OICMKCED_03995 1.5e-163 opuAC E glycine betaine
OICMKCED_03996 1.3e-127 opuAB P glycine betaine
OICMKCED_03997 5.1e-229 proV 3.6.3.32 E glycine betaine
OICMKCED_03998 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
OICMKCED_03999 3.2e-162 yceJ EGP Uncharacterised MFS-type transporter YbfB
OICMKCED_04000 6.6e-218 naiP P Uncharacterised MFS-type transporter YbfB
OICMKCED_04001 2e-192 yceH P Belongs to the TelA family
OICMKCED_04002 0.0 yceG S Putative component of 'biosynthetic module'
OICMKCED_04003 1.4e-136 terC P Protein of unknown function (DUF475)
OICMKCED_04004 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
OICMKCED_04005 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
OICMKCED_04006 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
OICMKCED_04007 4.2e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OICMKCED_04008 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OICMKCED_04009 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OICMKCED_04010 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
OICMKCED_04011 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
OICMKCED_04012 4.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
OICMKCED_04013 5.5e-174 S response regulator aspartate phosphatase
OICMKCED_04014 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
OICMKCED_04015 5.7e-267 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
OICMKCED_04016 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
OICMKCED_04017 6.6e-177 ycdA S Domain of unknown function (DUF5105)
OICMKCED_04018 3e-173 yccK C Aldo keto reductase
OICMKCED_04019 2.2e-202 natB CP ABC-2 family transporter protein
OICMKCED_04020 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
OICMKCED_04021 1.2e-126 lytR_2 T LytTr DNA-binding domain
OICMKCED_04022 8.3e-155 2.7.13.3 T GHKL domain
OICMKCED_04023 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
OICMKCED_04024 7.1e-57 S RDD family
OICMKCED_04025 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OICMKCED_04026 6.3e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
OICMKCED_04027 1.3e-99 yxaF K Transcriptional regulator
OICMKCED_04028 7.4e-224 lmrB EGP the major facilitator superfamily
OICMKCED_04029 6.6e-204 ycbU E Selenocysteine lyase
OICMKCED_04030 1.7e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OICMKCED_04031 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OICMKCED_04032 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OICMKCED_04033 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
OICMKCED_04034 9.5e-135 ycbR T vWA found in TerF C terminus
OICMKCED_04035 2.2e-78 sleB 3.5.1.28 M Cell wall
OICMKCED_04036 1.2e-51 ycbP S Protein of unknown function (DUF2512)
OICMKCED_04037 3.3e-113 S ABC-2 family transporter protein
OICMKCED_04038 5.9e-166 ycbN V ABC transporter, ATP-binding protein
OICMKCED_04039 4.2e-167 T PhoQ Sensor
OICMKCED_04040 9.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OICMKCED_04041 1.7e-168 eamA1 EG spore germination
OICMKCED_04042 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
OICMKCED_04043 1.2e-174 ycbJ S Macrolide 2'-phosphotransferase
OICMKCED_04044 4.5e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
OICMKCED_04045 2.1e-123 ycbG K FCD
OICMKCED_04046 1.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OICMKCED_04047 2.7e-255 gudP G COG0477 Permeases of the major facilitator superfamily
OICMKCED_04048 2.2e-271 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OICMKCED_04049 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
OICMKCED_04050 9e-170 glnL T Regulator
OICMKCED_04051 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
OICMKCED_04052 1.3e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
OICMKCED_04053 2.8e-255 agcS E Sodium alanine symporter
OICMKCED_04054 2.4e-178 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
OICMKCED_04055 4.8e-260 mmuP E amino acid
OICMKCED_04056 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OICMKCED_04058 4.9e-128 K UTRA
OICMKCED_04059 4.8e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OICMKCED_04060 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OICMKCED_04061 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OICMKCED_04062 3.9e-192 yceA S Belongs to the UPF0176 family
OICMKCED_04063 2.1e-252 S Erythromycin esterase
OICMKCED_04064 9.2e-46 ybfN
OICMKCED_04065 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
OICMKCED_04066 2.7e-85 ybfM S SNARE associated Golgi protein
OICMKCED_04067 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OICMKCED_04068 1.8e-167 S Alpha/beta hydrolase family
OICMKCED_04070 1.5e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
OICMKCED_04071 2.3e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OICMKCED_04072 2.3e-145 msmR K AraC-like ligand binding domain
OICMKCED_04073 8.8e-162 ybfH EG EamA-like transporter family
OICMKCED_04074 0.0 ybfG M Domain of unknown function (DUF1906)
OICMKCED_04076 1.1e-223 ybfB G COG0477 Permeases of the major facilitator superfamily
OICMKCED_04077 1.4e-170 ybfA 3.4.15.5 K FR47-like protein
OICMKCED_04078 8.5e-35 S Protein of unknown function (DUF2651)
OICMKCED_04079 7.3e-258 glpT G -transporter
OICMKCED_04080 1.8e-159 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OICMKCED_04081 4.1e-49 M PFAM Glycosyl transferase family 2
OICMKCED_04082 2.3e-290 ybeC E amino acid
OICMKCED_04083 4.9e-41 ybyB
OICMKCED_04084 2.3e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
OICMKCED_04085 8e-151 ybxI 3.5.2.6 V beta-lactamase
OICMKCED_04086 4.9e-30 ybxH S Family of unknown function (DUF5370)
OICMKCED_04087 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
OICMKCED_04088 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
OICMKCED_04089 2.8e-213 ybdO S Domain of unknown function (DUF4885)
OICMKCED_04090 3.8e-151 ybdN
OICMKCED_04091 3.7e-137 KLT Protein tyrosine kinase
OICMKCED_04093 2.2e-171 T His Kinase A (phospho-acceptor) domain
OICMKCED_04094 4.2e-121 T Transcriptional regulatory protein, C terminal
OICMKCED_04095 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OICMKCED_04096 4.7e-55
OICMKCED_04097 5.9e-203 ybcL EGP Major facilitator Superfamily
OICMKCED_04098 5.1e-50 ybzH K Helix-turn-helix domain
OICMKCED_04099 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
OICMKCED_04100 1.9e-46
OICMKCED_04101 3.8e-93 can 4.2.1.1 P carbonic anhydrase
OICMKCED_04102 0.0 ybcC S Belongs to the UPF0753 family
OICMKCED_04103 8.8e-276 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OICMKCED_04104 9.6e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OICMKCED_04105 3.2e-118 adaA 3.2.2.21 K Transcriptional regulator
OICMKCED_04106 1e-170 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OICMKCED_04107 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OICMKCED_04108 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OICMKCED_04109 1.5e-224 ybbR S protein conserved in bacteria
OICMKCED_04110 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OICMKCED_04111 6.3e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
OICMKCED_04112 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
OICMKCED_04115 2e-08
OICMKCED_04118 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
OICMKCED_04119 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
OICMKCED_04120 1.2e-84 gerD
OICMKCED_04121 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
OICMKCED_04122 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OICMKCED_04123 9.7e-66 ybaK S Protein of unknown function (DUF2521)
OICMKCED_04124 8.2e-145 ybaJ Q Methyltransferase domain
OICMKCED_04125 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
OICMKCED_04126 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OICMKCED_04127 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OICMKCED_04128 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OICMKCED_04129 2.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OICMKCED_04130 1.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OICMKCED_04131 3.6e-58 rplQ J Ribosomal protein L17
OICMKCED_04132 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OICMKCED_04133 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OICMKCED_04134 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OICMKCED_04135 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
OICMKCED_04136 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OICMKCED_04137 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
OICMKCED_04138 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OICMKCED_04139 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OICMKCED_04140 1.8e-72 rplO J binds to the 23S rRNA
OICMKCED_04141 1.9e-23 rpmD J Ribosomal protein L30
OICMKCED_04142 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OICMKCED_04143 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OICMKCED_04144 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OICMKCED_04145 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OICMKCED_04146 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OICMKCED_04147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OICMKCED_04148 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OICMKCED_04149 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OICMKCED_04150 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OICMKCED_04151 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
OICMKCED_04152 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OICMKCED_04153 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OICMKCED_04154 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OICMKCED_04155 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OICMKCED_04156 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OICMKCED_04157 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OICMKCED_04158 3e-105 rplD J Forms part of the polypeptide exit tunnel
OICMKCED_04159 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OICMKCED_04160 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
OICMKCED_04161 8.2e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
OICMKCED_04162 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OICMKCED_04163 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OICMKCED_04164 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OICMKCED_04165 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OICMKCED_04166 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
OICMKCED_04167 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OICMKCED_04168 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OICMKCED_04169 3.1e-107 rsmC 2.1.1.172 J Methyltransferase
OICMKCED_04170 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OICMKCED_04171 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OICMKCED_04172 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OICMKCED_04173 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OICMKCED_04174 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
OICMKCED_04175 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OICMKCED_04176 4.4e-115 sigH K Belongs to the sigma-70 factor family
OICMKCED_04177 1.2e-88 yacP S RNA-binding protein containing a PIN domain
OICMKCED_04178 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OICMKCED_04179 1.2e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OICMKCED_04180 2.1e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OICMKCED_04181 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
OICMKCED_04182 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OICMKCED_04183 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
OICMKCED_04184 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
OICMKCED_04185 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
OICMKCED_04186 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OICMKCED_04187 3.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OICMKCED_04188 0.0 clpC O Belongs to the ClpA ClpB family
OICMKCED_04189 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
OICMKCED_04190 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
OICMKCED_04191 2.9e-76 ctsR K Belongs to the CtsR family
OICMKCED_04196 2e-08
OICMKCED_04210 4.9e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OICMKCED_04211 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OICMKCED_04212 4.1e-30 yazB K transcriptional
OICMKCED_04213 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OICMKCED_04214 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OICMKCED_04215 2.5e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OICMKCED_04216 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
OICMKCED_04217 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
OICMKCED_04218 9.1e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OICMKCED_04219 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OICMKCED_04220 7.2e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
OICMKCED_04221 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OICMKCED_04222 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OICMKCED_04223 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OICMKCED_04224 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OICMKCED_04225 8e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OICMKCED_04226 3.7e-185 KLT serine threonine protein kinase
OICMKCED_04227 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
OICMKCED_04228 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
OICMKCED_04231 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
OICMKCED_04232 1.1e-44 divIC D Septum formation initiator
OICMKCED_04233 4.3e-107 yabQ S spore cortex biosynthesis protein
OICMKCED_04234 1.5e-49 yabP S Sporulation protein YabP
OICMKCED_04235 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
OICMKCED_04236 6.6e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
OICMKCED_04237 1.2e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OICMKCED_04238 1.5e-92 spoVT K stage V sporulation protein
OICMKCED_04239 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OICMKCED_04240 2.4e-39 yabK S Peptide ABC transporter permease
OICMKCED_04241 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OICMKCED_04242 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OICMKCED_04243 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OICMKCED_04244 7.3e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OICMKCED_04245 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
OICMKCED_04246 1.1e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
OICMKCED_04247 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
OICMKCED_04248 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OICMKCED_04249 7.8e-39 veg S protein conserved in bacteria
OICMKCED_04250 1.8e-135 yabG S peptidase
OICMKCED_04251 3.4e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OICMKCED_04252 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OICMKCED_04253 2e-167 rpfB GH23 T protein conserved in bacteria
OICMKCED_04254 3.4e-143 tatD L hydrolase, TatD
OICMKCED_04255 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OICMKCED_04256 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
OICMKCED_04257 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OICMKCED_04258 1.5e-49 yazA L endonuclease containing a URI domain
OICMKCED_04259 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
OICMKCED_04260 4.8e-31 yabA L Involved in initiation control of chromosome replication
OICMKCED_04261 2.1e-146 yaaT S stage 0 sporulation protein
OICMKCED_04262 2.2e-182 holB 2.7.7.7 L DNA polymerase III
OICMKCED_04263 1.5e-71 yaaR S protein conserved in bacteria
OICMKCED_04264 2.2e-54 yaaQ S protein conserved in bacteria
OICMKCED_04265 6.9e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OICMKCED_04266 5.1e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
OICMKCED_04267 9.9e-203 yaaN P Belongs to the TelA family
OICMKCED_04268 2.4e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
OICMKCED_04269 3.4e-31 csfB S Inhibitor of sigma-G Gin
OICMKCED_04270 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
OICMKCED_04271 7.9e-32 yaaL S Protein of unknown function (DUF2508)
OICMKCED_04272 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OICMKCED_04273 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OICMKCED_04274 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OICMKCED_04275 4.3e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OICMKCED_04276 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
OICMKCED_04277 1.2e-212 yaaH M Glycoside Hydrolase Family
OICMKCED_04278 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
OICMKCED_04279 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
OICMKCED_04280 1.3e-09
OICMKCED_04281 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OICMKCED_04282 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OICMKCED_04283 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OICMKCED_04284 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OICMKCED_04285 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
OICMKCED_04286 1e-181 yaaC S YaaC-like Protein
OICMKCED_04289 3.4e-39 S COG NOG14552 non supervised orthologous group

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)