ORF_ID e_value Gene_name EC_number CAZy COGs Description
KEPPFGEB_00001 1.8e-234 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEPPFGEB_00002 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
KEPPFGEB_00003 1.7e-139 srfAD Q thioesterase
KEPPFGEB_00004 5.4e-223 EGP Major Facilitator Superfamily
KEPPFGEB_00005 6.7e-88 S YcxB-like protein
KEPPFGEB_00006 9.9e-161 ycxC EG EamA-like transporter family
KEPPFGEB_00007 1.1e-250 ycxD K GntR family transcriptional regulator
KEPPFGEB_00008 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
KEPPFGEB_00009 9.7e-115 yczE S membrane
KEPPFGEB_00010 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KEPPFGEB_00011 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
KEPPFGEB_00012 3.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KEPPFGEB_00013 1.9e-161 bsdA K LysR substrate binding domain
KEPPFGEB_00014 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KEPPFGEB_00015 4.5e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KEPPFGEB_00016 4e-39 bsdD 4.1.1.61 S response to toxic substance
KEPPFGEB_00017 3.1e-78 yclD
KEPPFGEB_00018 1.6e-157 yclE 3.4.11.5 S Alpha beta hydrolase
KEPPFGEB_00019 2.9e-263 dtpT E amino acid peptide transporter
KEPPFGEB_00020 3.2e-293 yclG M Pectate lyase superfamily protein
KEPPFGEB_00022 7.5e-281 gerKA EG Spore germination protein
KEPPFGEB_00023 1.6e-230 gerKC S spore germination
KEPPFGEB_00024 3e-196 gerKB F Spore germination protein
KEPPFGEB_00025 7.3e-121 yclH P ABC transporter
KEPPFGEB_00026 1.1e-195 yclI V ABC transporter (permease) YclI
KEPPFGEB_00027 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEPPFGEB_00028 1.1e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KEPPFGEB_00029 1.3e-77 S aspartate phosphatase
KEPPFGEB_00033 2.6e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
KEPPFGEB_00034 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEPPFGEB_00035 1.1e-162 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEPPFGEB_00036 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KEPPFGEB_00037 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KEPPFGEB_00038 1.2e-250 ycnB EGP Major facilitator Superfamily
KEPPFGEB_00039 5.5e-153 ycnC K Transcriptional regulator
KEPPFGEB_00040 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
KEPPFGEB_00041 1.6e-45 ycnE S Monooxygenase
KEPPFGEB_00042 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
KEPPFGEB_00043 1.5e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEPPFGEB_00044 5.3e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KEPPFGEB_00045 3.2e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEPPFGEB_00046 6.1e-149 glcU U Glucose uptake
KEPPFGEB_00047 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEPPFGEB_00048 1.4e-99 ycnI S protein conserved in bacteria
KEPPFGEB_00049 3.6e-307 ycnJ P protein, homolog of Cu resistance protein CopC
KEPPFGEB_00050 3.1e-104 ycnK K COG1349 Transcriptional regulators of sugar metabolism
KEPPFGEB_00051 3.4e-53
KEPPFGEB_00052 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
KEPPFGEB_00053 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KEPPFGEB_00054 1.4e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
KEPPFGEB_00055 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KEPPFGEB_00057 1.1e-74 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KEPPFGEB_00058 7e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
KEPPFGEB_00059 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KEPPFGEB_00061 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KEPPFGEB_00062 1.5e-138 ycsF S Belongs to the UPF0271 (lamB) family
KEPPFGEB_00063 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
KEPPFGEB_00064 3.7e-148 ycsI S Belongs to the D-glutamate cyclase family
KEPPFGEB_00065 9.4e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
KEPPFGEB_00066 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KEPPFGEB_00067 1.2e-132 kipR K Transcriptional regulator
KEPPFGEB_00068 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
KEPPFGEB_00070 1.4e-49 yczJ S biosynthesis
KEPPFGEB_00071 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KEPPFGEB_00072 8.1e-176 ydhF S Oxidoreductase
KEPPFGEB_00073 0.0 mtlR K transcriptional regulator, MtlR
KEPPFGEB_00074 2.3e-292 ydaB IQ acyl-CoA ligase
KEPPFGEB_00075 3.4e-98 ydaC Q Methyltransferase domain
KEPPFGEB_00076 4.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEPPFGEB_00077 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
KEPPFGEB_00078 1.5e-100 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KEPPFGEB_00079 6.8e-77 ydaG 1.4.3.5 S general stress protein
KEPPFGEB_00080 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KEPPFGEB_00081 3.6e-45 ydzA EGP Major facilitator Superfamily
KEPPFGEB_00082 2.5e-74 lrpC K Transcriptional regulator
KEPPFGEB_00083 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KEPPFGEB_00084 2.1e-207 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
KEPPFGEB_00085 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
KEPPFGEB_00086 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
KEPPFGEB_00087 4.5e-233 ydaM M Glycosyl transferase family group 2
KEPPFGEB_00088 0.0 ydaN S Bacterial cellulose synthase subunit
KEPPFGEB_00089 0.0 ydaO E amino acid
KEPPFGEB_00090 1.1e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KEPPFGEB_00091 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KEPPFGEB_00092 9.4e-40
KEPPFGEB_00093 1.1e-223 mntH P H( )-stimulated, divalent metal cation uptake system
KEPPFGEB_00095 1.3e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
KEPPFGEB_00096 3.2e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
KEPPFGEB_00098 8.9e-59 ydbB G Cupin domain
KEPPFGEB_00099 1.1e-62 ydbC S Domain of unknown function (DUF4937
KEPPFGEB_00100 3.5e-154 ydbD P Catalase
KEPPFGEB_00101 1.8e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KEPPFGEB_00102 1.3e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KEPPFGEB_00103 3.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
KEPPFGEB_00104 4.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KEPPFGEB_00105 2.2e-180 ydbI S AI-2E family transporter
KEPPFGEB_00106 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
KEPPFGEB_00107 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KEPPFGEB_00108 2.7e-52 ydbL
KEPPFGEB_00109 1.4e-217 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KEPPFGEB_00110 1.1e-18 S Fur-regulated basic protein B
KEPPFGEB_00111 2.2e-07 S Fur-regulated basic protein A
KEPPFGEB_00112 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KEPPFGEB_00113 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KEPPFGEB_00114 4.3e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KEPPFGEB_00115 2.7e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KEPPFGEB_00116 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KEPPFGEB_00117 2.1e-82 ydbS S Bacterial PH domain
KEPPFGEB_00118 3.3e-259 ydbT S Membrane
KEPPFGEB_00119 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KEPPFGEB_00120 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KEPPFGEB_00121 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KEPPFGEB_00122 2.6e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KEPPFGEB_00123 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KEPPFGEB_00124 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
KEPPFGEB_00125 1.3e-143 rsbR T Positive regulator of sigma-B
KEPPFGEB_00126 5.2e-57 rsbS T antagonist
KEPPFGEB_00127 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KEPPFGEB_00128 3.5e-188 rsbU 3.1.3.3 KT phosphatase
KEPPFGEB_00129 1.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
KEPPFGEB_00130 7.8e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KEPPFGEB_00131 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEPPFGEB_00132 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KEPPFGEB_00135 1.5e-82 ydcG S EVE domain
KEPPFGEB_00136 6.1e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
KEPPFGEB_00137 0.0 yhgF K COG2183 Transcriptional accessory protein
KEPPFGEB_00138 8.9e-83 ydcK S Belongs to the SprT family
KEPPFGEB_00146 4.6e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEPPFGEB_00147 2.4e-71 lrpA K transcriptional
KEPPFGEB_00148 1.5e-77 lrpB K transcriptional
KEPPFGEB_00149 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
KEPPFGEB_00150 2e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
KEPPFGEB_00151 2.3e-224 ydeG EGP Major facilitator Superfamily
KEPPFGEB_00152 3.2e-69 L HNH nucleases
KEPPFGEB_00153 6.3e-193 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KEPPFGEB_00154 8.7e-30 cspL K Cold shock
KEPPFGEB_00155 6.1e-79 carD K Transcription factor
KEPPFGEB_00156 1.5e-163 rhaS5 K AraC-like ligand binding domain
KEPPFGEB_00157 1.4e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KEPPFGEB_00158 8.1e-165 ydeE K AraC family transcriptional regulator
KEPPFGEB_00159 4.3e-261 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEPPFGEB_00160 9.9e-220 ydeG EGP Major facilitator superfamily
KEPPFGEB_00161 2.1e-45 ydeH
KEPPFGEB_00162 7.8e-103 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
KEPPFGEB_00163 2.2e-114
KEPPFGEB_00164 5.9e-152 ydeK EG -transporter
KEPPFGEB_00165 6.6e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEPPFGEB_00166 4.2e-74 maoC I N-terminal half of MaoC dehydratase
KEPPFGEB_00167 1.1e-104 ydeN S Serine hydrolase
KEPPFGEB_00168 2.6e-55 K HxlR-like helix-turn-helix
KEPPFGEB_00169 1.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KEPPFGEB_00170 8.2e-57 arsR K transcriptional
KEPPFGEB_00171 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KEPPFGEB_00172 9.2e-144 ydfB J GNAT acetyltransferase
KEPPFGEB_00173 8.3e-149 lytR K Transcriptional regulator
KEPPFGEB_00174 4.5e-122 nodB1 G deacetylase
KEPPFGEB_00175 2.1e-157
KEPPFGEB_00176 4.5e-213 T GHKL domain
KEPPFGEB_00177 3.4e-122 T Transcriptional regulatory protein, C terminal
KEPPFGEB_00178 1.8e-151 ydfC EG EamA-like transporter family
KEPPFGEB_00179 1.1e-272 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEPPFGEB_00180 1.4e-115 ydfE S Flavin reductase like domain
KEPPFGEB_00181 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
KEPPFGEB_00182 1.3e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KEPPFGEB_00184 1.9e-177 ydfH 2.7.13.3 T Histidine kinase
KEPPFGEB_00185 9.3e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEPPFGEB_00186 0.0 ydfJ S drug exporters of the RND superfamily
KEPPFGEB_00187 8.5e-117 S Protein of unknown function (DUF554)
KEPPFGEB_00188 9.2e-147 K Bacterial transcription activator, effector binding domain
KEPPFGEB_00189 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KEPPFGEB_00190 2e-109 ydfN C nitroreductase
KEPPFGEB_00191 4.9e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
KEPPFGEB_00192 8.8e-63 mhqP S DoxX
KEPPFGEB_00193 1.3e-57 traF CO Thioredoxin
KEPPFGEB_00194 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
KEPPFGEB_00195 6.3e-29
KEPPFGEB_00197 8.2e-95 ydfR S Protein of unknown function (DUF421)
KEPPFGEB_00198 5.2e-122 ydfS S Protein of unknown function (DUF421)
KEPPFGEB_00199 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
KEPPFGEB_00200 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
KEPPFGEB_00201 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
KEPPFGEB_00202 2.8e-100 K Bacterial regulatory proteins, tetR family
KEPPFGEB_00203 2.8e-52 S DoxX-like family
KEPPFGEB_00204 1.9e-83 yycN 2.3.1.128 K Acetyltransferase
KEPPFGEB_00205 2.4e-303 expZ S ABC transporter
KEPPFGEB_00206 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KEPPFGEB_00207 1.4e-87 dinB S DinB family
KEPPFGEB_00208 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
KEPPFGEB_00209 0.0 ydgH S drug exporters of the RND superfamily
KEPPFGEB_00210 1e-113 drgA C nitroreductase
KEPPFGEB_00211 3.2e-69 ydgJ K Winged helix DNA-binding domain
KEPPFGEB_00212 2.2e-208 tcaB EGP Major facilitator Superfamily
KEPPFGEB_00213 1.2e-121 ydhB S membrane transporter protein
KEPPFGEB_00214 6.5e-122 ydhC K FCD
KEPPFGEB_00215 7.7e-241 ydhD M Glycosyl hydrolase
KEPPFGEB_00216 4.5e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KEPPFGEB_00217 1.9e-124
KEPPFGEB_00218 9e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KEPPFGEB_00219 1.1e-67 frataxin S Domain of unknown function (DU1801)
KEPPFGEB_00221 2.1e-82 K Acetyltransferase (GNAT) domain
KEPPFGEB_00222 1.1e-178 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KEPPFGEB_00223 2.3e-96 ydhK M Protein of unknown function (DUF1541)
KEPPFGEB_00224 1.9e-198 pbuE EGP Major facilitator Superfamily
KEPPFGEB_00225 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
KEPPFGEB_00226 4.3e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
KEPPFGEB_00227 1.4e-232 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KEPPFGEB_00228 9e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KEPPFGEB_00229 3.7e-131 ydhQ K UTRA
KEPPFGEB_00230 2.1e-168 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KEPPFGEB_00231 1.4e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
KEPPFGEB_00232 1.7e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
KEPPFGEB_00233 2.3e-156 ydhU P Catalase
KEPPFGEB_00236 2.2e-30 csfB S Inhibitor of sigma-G Gin
KEPPFGEB_00237 3.4e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KEPPFGEB_00238 4.9e-202 yaaN P Belongs to the TelA family
KEPPFGEB_00239 1.3e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KEPPFGEB_00240 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KEPPFGEB_00241 2.2e-54 yaaQ S protein conserved in bacteria
KEPPFGEB_00242 1.5e-71 yaaR S protein conserved in bacteria
KEPPFGEB_00243 3.1e-181 holB 2.7.7.7 L DNA polymerase III
KEPPFGEB_00244 6.1e-146 yaaT S stage 0 sporulation protein
KEPPFGEB_00245 4.8e-31 yabA L Involved in initiation control of chromosome replication
KEPPFGEB_00246 1.2e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
KEPPFGEB_00247 1.5e-49 yazA L endonuclease containing a URI domain
KEPPFGEB_00248 4.6e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KEPPFGEB_00249 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
KEPPFGEB_00250 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KEPPFGEB_00251 3.4e-143 tatD L hydrolase, TatD
KEPPFGEB_00252 2e-167 rpfB GH23 T protein conserved in bacteria
KEPPFGEB_00253 6.7e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KEPPFGEB_00254 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KEPPFGEB_00255 1.6e-136 yabG S peptidase
KEPPFGEB_00256 7.8e-39 veg S protein conserved in bacteria
KEPPFGEB_00257 8.3e-27 sspF S DNA topological change
KEPPFGEB_00258 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KEPPFGEB_00259 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KEPPFGEB_00260 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KEPPFGEB_00261 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KEPPFGEB_00262 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KEPPFGEB_00263 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KEPPFGEB_00264 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KEPPFGEB_00265 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KEPPFGEB_00266 2.4e-39 yabK S Peptide ABC transporter permease
KEPPFGEB_00267 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KEPPFGEB_00268 1.5e-92 spoVT K stage V sporulation protein
KEPPFGEB_00269 9.3e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEPPFGEB_00270 5.8e-240 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KEPPFGEB_00271 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KEPPFGEB_00272 1.5e-49 yabP S Sporulation protein YabP
KEPPFGEB_00273 9.5e-107 yabQ S spore cortex biosynthesis protein
KEPPFGEB_00274 1.1e-44 divIC D Septum formation initiator
KEPPFGEB_00275 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KEPPFGEB_00278 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KEPPFGEB_00279 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
KEPPFGEB_00280 1.3e-185 KLT serine threonine protein kinase
KEPPFGEB_00281 1.5e-269 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KEPPFGEB_00282 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KEPPFGEB_00283 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KEPPFGEB_00284 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KEPPFGEB_00285 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KEPPFGEB_00286 7.2e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
KEPPFGEB_00287 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KEPPFGEB_00288 9.1e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KEPPFGEB_00289 2.1e-105 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KEPPFGEB_00290 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
KEPPFGEB_00291 5.9e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KEPPFGEB_00292 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KEPPFGEB_00293 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KEPPFGEB_00294 4.1e-30 yazB K transcriptional
KEPPFGEB_00295 3.2e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KEPPFGEB_00296 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KEPPFGEB_00297 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
KEPPFGEB_00298 2.9e-93 M1-753 M FR47-like protein
KEPPFGEB_00299 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
KEPPFGEB_00300 1.9e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KEPPFGEB_00301 1.1e-83 yuaE S DinB superfamily
KEPPFGEB_00302 3.3e-106 yuaD
KEPPFGEB_00303 3.2e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
KEPPFGEB_00304 4e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KEPPFGEB_00305 3.6e-94 yuaC K Belongs to the GbsR family
KEPPFGEB_00306 2.2e-91 yuaB
KEPPFGEB_00307 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
KEPPFGEB_00308 1.6e-236 ktrB P Potassium
KEPPFGEB_00309 1e-38 yiaA S yiaA/B two helix domain
KEPPFGEB_00310 5.4e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KEPPFGEB_00311 1.4e-273 yubD P Major Facilitator Superfamily
KEPPFGEB_00312 1.1e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
KEPPFGEB_00314 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KEPPFGEB_00315 9.1e-196 yubA S transporter activity
KEPPFGEB_00316 9.7e-183 ygjR S Oxidoreductase
KEPPFGEB_00317 9.7e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
KEPPFGEB_00318 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
KEPPFGEB_00319 2.5e-280 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KEPPFGEB_00320 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
KEPPFGEB_00321 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
KEPPFGEB_00322 5.1e-239 mcpA NT chemotaxis protein
KEPPFGEB_00323 8.5e-295 mcpA NT chemotaxis protein
KEPPFGEB_00324 1.1e-222 mcpA NT chemotaxis protein
KEPPFGEB_00325 7.1e-225 mcpA NT chemotaxis protein
KEPPFGEB_00326 2.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
KEPPFGEB_00327 1e-35
KEPPFGEB_00328 1.8e-71 yugU S Uncharacterised protein family UPF0047
KEPPFGEB_00329 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KEPPFGEB_00330 1.3e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
KEPPFGEB_00331 1.4e-116 yugP S Zn-dependent protease
KEPPFGEB_00332 7.4e-37
KEPPFGEB_00333 1.1e-53 mstX S Membrane-integrating protein Mistic
KEPPFGEB_00334 2.2e-182 yugO P COG1226 Kef-type K transport systems
KEPPFGEB_00335 1.3e-72 yugN S YugN-like family
KEPPFGEB_00337 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
KEPPFGEB_00338 7.6e-227 yugK C Dehydrogenase
KEPPFGEB_00339 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KEPPFGEB_00340 1.1e-34 yuzA S Domain of unknown function (DUF378)
KEPPFGEB_00341 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KEPPFGEB_00342 8.1e-199 yugH 2.6.1.1 E Aminotransferase
KEPPFGEB_00343 1.6e-85 alaR K Transcriptional regulator
KEPPFGEB_00344 4.2e-155 yugF I Hydrolase
KEPPFGEB_00345 1.1e-40 yugE S Domain of unknown function (DUF1871)
KEPPFGEB_00346 4.9e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KEPPFGEB_00347 1.3e-232 T PhoQ Sensor
KEPPFGEB_00348 7.4e-70 kapB G Kinase associated protein B
KEPPFGEB_00349 4.2e-115 kapD L the KinA pathway to sporulation
KEPPFGEB_00351 4.2e-184 yuxJ EGP Major facilitator Superfamily
KEPPFGEB_00352 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
KEPPFGEB_00353 1.8e-74 yuxK S protein conserved in bacteria
KEPPFGEB_00354 6.3e-78 yufK S Family of unknown function (DUF5366)
KEPPFGEB_00355 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KEPPFGEB_00356 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
KEPPFGEB_00357 2.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KEPPFGEB_00358 9.2e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KEPPFGEB_00359 1.9e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
KEPPFGEB_00360 9.5e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
KEPPFGEB_00361 1.3e-233 maeN C COG3493 Na citrate symporter
KEPPFGEB_00362 5e-15
KEPPFGEB_00363 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KEPPFGEB_00364 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEPPFGEB_00365 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEPPFGEB_00366 7.1e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEPPFGEB_00367 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEPPFGEB_00368 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEPPFGEB_00369 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
KEPPFGEB_00370 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
KEPPFGEB_00371 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEPPFGEB_00372 0.0 comP 2.7.13.3 T Histidine kinase
KEPPFGEB_00374 2.1e-161 comQ H Polyprenyl synthetase
KEPPFGEB_00376 8.5e-23 yuzC
KEPPFGEB_00377 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
KEPPFGEB_00378 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KEPPFGEB_00379 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
KEPPFGEB_00380 1.8e-66 yueI S Protein of unknown function (DUF1694)
KEPPFGEB_00381 2.8e-38 yueH S YueH-like protein
KEPPFGEB_00382 6.6e-31 yueG S Spore germination protein gerPA/gerPF
KEPPFGEB_00383 3.2e-190 yueF S transporter activity
KEPPFGEB_00384 1.2e-70 S Protein of unknown function (DUF2283)
KEPPFGEB_00385 2.9e-24 S Protein of unknown function (DUF2642)
KEPPFGEB_00386 4.8e-96 yueE S phosphohydrolase
KEPPFGEB_00387 7.1e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEPPFGEB_00388 3.3e-64 yueC S Family of unknown function (DUF5383)
KEPPFGEB_00389 0.0 esaA S type VII secretion protein EsaA
KEPPFGEB_00390 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KEPPFGEB_00391 3.4e-210 essB S WXG100 protein secretion system (Wss), protein YukC
KEPPFGEB_00392 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
KEPPFGEB_00393 2.8e-45 esxA S Belongs to the WXG100 family
KEPPFGEB_00394 4.7e-227 yukF QT Transcriptional regulator
KEPPFGEB_00395 5.2e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KEPPFGEB_00396 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
KEPPFGEB_00397 5e-36 mbtH S MbtH-like protein
KEPPFGEB_00398 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEPPFGEB_00399 3.1e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
KEPPFGEB_00400 4.5e-311 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
KEPPFGEB_00401 5e-226 entC 5.4.4.2 HQ Isochorismate synthase
KEPPFGEB_00402 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEPPFGEB_00403 3.9e-167 besA S Putative esterase
KEPPFGEB_00404 1.7e-121 yuiH S Oxidoreductase molybdopterin binding domain
KEPPFGEB_00405 2.6e-93 bioY S Biotin biosynthesis protein
KEPPFGEB_00406 3.9e-211 yuiF S antiporter
KEPPFGEB_00407 2.9e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KEPPFGEB_00408 1.2e-77 yuiD S protein conserved in bacteria
KEPPFGEB_00409 1e-116 yuiC S protein conserved in bacteria
KEPPFGEB_00410 1.9e-26 yuiB S Putative membrane protein
KEPPFGEB_00411 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
KEPPFGEB_00412 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
KEPPFGEB_00414 2.1e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KEPPFGEB_00415 5e-116 paiB K Putative FMN-binding domain
KEPPFGEB_00416 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEPPFGEB_00417 3.7e-63 erpA S Belongs to the HesB IscA family
KEPPFGEB_00418 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KEPPFGEB_00419 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KEPPFGEB_00420 3.2e-39 yuzB S Belongs to the UPF0349 family
KEPPFGEB_00421 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
KEPPFGEB_00422 3e-56 yuzD S protein conserved in bacteria
KEPPFGEB_00423 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
KEPPFGEB_00424 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
KEPPFGEB_00425 1.9e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KEPPFGEB_00426 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KEPPFGEB_00427 7.9e-241 hom 1.1.1.3 E homoserine dehydrogenase
KEPPFGEB_00428 2.5e-197 yutH S Spore coat protein
KEPPFGEB_00429 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KEPPFGEB_00430 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KEPPFGEB_00431 1e-75 yutE S Protein of unknown function DUF86
KEPPFGEB_00432 9.7e-48 yutD S protein conserved in bacteria
KEPPFGEB_00433 2.4e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KEPPFGEB_00434 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KEPPFGEB_00435 4.5e-196 lytH M Peptidase, M23
KEPPFGEB_00436 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
KEPPFGEB_00437 1.1e-47 yunC S Domain of unknown function (DUF1805)
KEPPFGEB_00438 9.2e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KEPPFGEB_00439 2e-141 yunE S membrane transporter protein
KEPPFGEB_00440 4.3e-171 yunF S Protein of unknown function DUF72
KEPPFGEB_00441 8.2e-60 yunG
KEPPFGEB_00442 2.8e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KEPPFGEB_00443 4.1e-300 pucR QT COG2508 Regulator of polyketide synthase expression
KEPPFGEB_00444 4.1e-232 pbuX F Permease family
KEPPFGEB_00445 3.3e-223 pbuX F xanthine
KEPPFGEB_00446 1.9e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
KEPPFGEB_00447 1.1e-53 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KEPPFGEB_00448 6.9e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KEPPFGEB_00449 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KEPPFGEB_00450 2.9e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KEPPFGEB_00451 5.3e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
KEPPFGEB_00452 5.2e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KEPPFGEB_00453 4.3e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KEPPFGEB_00454 7.5e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KEPPFGEB_00455 3.5e-168 bsn L Ribonuclease
KEPPFGEB_00456 4.5e-205 msmX P Belongs to the ABC transporter superfamily
KEPPFGEB_00457 3.3e-135 yurK K UTRA
KEPPFGEB_00458 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
KEPPFGEB_00459 1.6e-168 yurM P COG0395 ABC-type sugar transport system, permease component
KEPPFGEB_00460 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
KEPPFGEB_00461 1.4e-237 yurO G COG1653 ABC-type sugar transport system, periplasmic component
KEPPFGEB_00462 4.4e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KEPPFGEB_00463 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
KEPPFGEB_00464 3.8e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KEPPFGEB_00466 1e-41
KEPPFGEB_00467 2.7e-64 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEPPFGEB_00468 3.5e-271 sufB O FeS cluster assembly
KEPPFGEB_00469 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KEPPFGEB_00470 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KEPPFGEB_00471 1.4e-245 sufD O assembly protein SufD
KEPPFGEB_00472 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KEPPFGEB_00473 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KEPPFGEB_00474 9.4e-147 metQ P Belongs to the NlpA lipoprotein family
KEPPFGEB_00475 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
KEPPFGEB_00476 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KEPPFGEB_00477 2.4e-56 yusD S SCP-2 sterol transfer family
KEPPFGEB_00478 5.6e-55 traF CO Thioredoxin
KEPPFGEB_00479 1.3e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
KEPPFGEB_00480 1.1e-39 yusG S Protein of unknown function (DUF2553)
KEPPFGEB_00481 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KEPPFGEB_00482 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
KEPPFGEB_00483 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KEPPFGEB_00484 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
KEPPFGEB_00485 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KEPPFGEB_00486 8.1e-09 S YuzL-like protein
KEPPFGEB_00487 1.3e-162 fadM E Proline dehydrogenase
KEPPFGEB_00488 5.1e-40
KEPPFGEB_00489 5.4e-53 yusN M Coat F domain
KEPPFGEB_00490 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
KEPPFGEB_00491 1.1e-292 yusP P Major facilitator superfamily
KEPPFGEB_00492 2.7e-64 yusQ S Tautomerase enzyme
KEPPFGEB_00493 1.3e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEPPFGEB_00494 2.2e-157 yusT K LysR substrate binding domain
KEPPFGEB_00495 5.6e-39 yusU S Protein of unknown function (DUF2573)
KEPPFGEB_00496 3.9e-153 yusV 3.6.3.34 HP ABC transporter
KEPPFGEB_00497 2.5e-66 S YusW-like protein
KEPPFGEB_00498 4.2e-301 pepF2 E COG1164 Oligoendopeptidase F
KEPPFGEB_00499 1.5e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEPPFGEB_00500 1.8e-78 dps P Ferritin-like domain
KEPPFGEB_00501 6.2e-236 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KEPPFGEB_00502 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEPPFGEB_00503 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
KEPPFGEB_00504 4.3e-158 yuxN K Transcriptional regulator
KEPPFGEB_00505 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KEPPFGEB_00506 3.9e-24 S Protein of unknown function (DUF3970)
KEPPFGEB_00507 3.1e-246 gerAA EG Spore germination protein
KEPPFGEB_00508 3.2e-195 gerAB E Spore germination protein
KEPPFGEB_00509 1.1e-182 gerAC S Spore germination B3/ GerAC like, C-terminal
KEPPFGEB_00510 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEPPFGEB_00511 1.3e-185 vraS 2.7.13.3 T Histidine kinase
KEPPFGEB_00512 3.6e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
KEPPFGEB_00513 1.6e-125 liaG S Putative adhesin
KEPPFGEB_00514 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KEPPFGEB_00515 2.8e-61 liaI S membrane
KEPPFGEB_00516 1.2e-225 yvqJ EGP Major facilitator Superfamily
KEPPFGEB_00517 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
KEPPFGEB_00518 5.2e-240 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KEPPFGEB_00519 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEPPFGEB_00520 2.2e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KEPPFGEB_00521 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEPPFGEB_00522 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
KEPPFGEB_00523 0.0 T PhoQ Sensor
KEPPFGEB_00524 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEPPFGEB_00525 7.2e-23
KEPPFGEB_00526 1.9e-98 yvrI K RNA polymerase
KEPPFGEB_00527 2.4e-19 S YvrJ protein family
KEPPFGEB_00528 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
KEPPFGEB_00529 1.3e-64 yvrL S Regulatory protein YrvL
KEPPFGEB_00530 5.2e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
KEPPFGEB_00531 7.9e-123 macB V ABC transporter, ATP-binding protein
KEPPFGEB_00532 6.9e-175 M Efflux transporter rnd family, mfp subunit
KEPPFGEB_00533 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
KEPPFGEB_00534 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEPPFGEB_00535 6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEPPFGEB_00536 1.2e-177 fhuD P ABC transporter
KEPPFGEB_00538 4.9e-236 yvsH E Arginine ornithine antiporter
KEPPFGEB_00539 6.5e-16 S Small spore protein J (Spore_SspJ)
KEPPFGEB_00540 2.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
KEPPFGEB_00541 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KEPPFGEB_00542 7e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
KEPPFGEB_00543 6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
KEPPFGEB_00544 3.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
KEPPFGEB_00545 1.1e-155 yvgN S reductase
KEPPFGEB_00546 5.4e-86 yvgO
KEPPFGEB_00547 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KEPPFGEB_00548 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KEPPFGEB_00549 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KEPPFGEB_00550 0.0 helD 3.6.4.12 L DNA helicase
KEPPFGEB_00552 1.6e-106 yvgT S membrane
KEPPFGEB_00553 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
KEPPFGEB_00554 1.6e-104 bdbD O Thioredoxin
KEPPFGEB_00555 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KEPPFGEB_00556 0.0 copA 3.6.3.54 P P-type ATPase
KEPPFGEB_00557 5.9e-29 copZ P Copper resistance protein CopZ
KEPPFGEB_00558 2.2e-48 csoR S transcriptional
KEPPFGEB_00559 1.1e-195 yvaA 1.1.1.371 S Oxidoreductase
KEPPFGEB_00560 2.7e-117 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KEPPFGEB_00561 0.0 yvaC S Fusaric acid resistance protein-like
KEPPFGEB_00562 4.8e-72 yvaD S Family of unknown function (DUF5360)
KEPPFGEB_00563 2.6e-53 yvaE P Small Multidrug Resistance protein
KEPPFGEB_00564 1.9e-98 K Bacterial regulatory proteins, tetR family
KEPPFGEB_00565 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEPPFGEB_00566 1.8e-15
KEPPFGEB_00569 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KEPPFGEB_00570 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KEPPFGEB_00571 3.7e-142 est 3.1.1.1 S Carboxylesterase
KEPPFGEB_00572 2.4e-23 secG U Preprotein translocase subunit SecG
KEPPFGEB_00573 3.1e-152 yvaM S Serine aminopeptidase, S33
KEPPFGEB_00574 9.8e-36 yvzC K Transcriptional
KEPPFGEB_00575 1.2e-68 K transcriptional
KEPPFGEB_00576 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
KEPPFGEB_00577 2.2e-54 yodB K transcriptional
KEPPFGEB_00578 1.1e-218 NT chemotaxis protein
KEPPFGEB_00579 2.3e-153 T His Kinase A (phosphoacceptor) domain
KEPPFGEB_00580 2.5e-105 K Transcriptional regulatory protein, C terminal
KEPPFGEB_00581 1.3e-81 mutG S ABC-2 family transporter protein
KEPPFGEB_00582 1.5e-87 spaE S ABC-2 family transporter protein
KEPPFGEB_00583 4.2e-103 mutF V ABC transporter, ATP-binding protein
KEPPFGEB_00585 1.1e-09 S Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
KEPPFGEB_00586 2.1e-95 spaC2 V PFAM Lanthionine synthetase
KEPPFGEB_00587 1.3e-156 spaT V ABC transporter
KEPPFGEB_00588 3.7e-196 spaB S Lantibiotic dehydratase, C terminus
KEPPFGEB_00589 4.7e-104 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KEPPFGEB_00590 4.7e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KEPPFGEB_00591 9.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KEPPFGEB_00592 3.7e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KEPPFGEB_00593 3.3e-60 yvbF K Belongs to the GbsR family
KEPPFGEB_00594 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KEPPFGEB_00595 3.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KEPPFGEB_00596 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KEPPFGEB_00597 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KEPPFGEB_00598 1.3e-96 yvbF K Belongs to the GbsR family
KEPPFGEB_00599 8.3e-103 yvbG U UPF0056 membrane protein
KEPPFGEB_00600 1.9e-112 yvbH S YvbH-like oligomerisation region
KEPPFGEB_00601 1.4e-122 exoY M Membrane
KEPPFGEB_00602 0.0 tcaA S response to antibiotic
KEPPFGEB_00603 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
KEPPFGEB_00604 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KEPPFGEB_00605 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KEPPFGEB_00606 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KEPPFGEB_00607 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KEPPFGEB_00608 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KEPPFGEB_00609 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KEPPFGEB_00610 1.6e-252 araE EGP Major facilitator Superfamily
KEPPFGEB_00611 5.5e-203 araR K transcriptional
KEPPFGEB_00612 6.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEPPFGEB_00613 2.2e-99 yvbU K Transcriptional regulator
KEPPFGEB_00614 1.2e-25 yvbU K Transcriptional regulator
KEPPFGEB_00615 7.2e-156 yvbV EG EamA-like transporter family
KEPPFGEB_00616 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
KEPPFGEB_00617 2.9e-193 yvbX S Glycosyl hydrolase
KEPPFGEB_00618 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KEPPFGEB_00619 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KEPPFGEB_00620 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KEPPFGEB_00621 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEPPFGEB_00622 2.1e-197 desK 2.7.13.3 T Histidine kinase
KEPPFGEB_00623 4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
KEPPFGEB_00624 4.9e-157 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
KEPPFGEB_00626 7.5e-157 rsbQ S Alpha/beta hydrolase family
KEPPFGEB_00627 1.4e-199 rsbU 3.1.3.3 T response regulator
KEPPFGEB_00628 1.6e-249 galA 3.2.1.89 G arabinogalactan
KEPPFGEB_00629 0.0 lacA 3.2.1.23 G beta-galactosidase
KEPPFGEB_00630 7.2e-150 ganQ P transport
KEPPFGEB_00631 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
KEPPFGEB_00632 6.1e-230 cycB G COG2182 Maltose-binding periplasmic proteins domains
KEPPFGEB_00633 1.8e-184 lacR K Transcriptional regulator
KEPPFGEB_00634 1e-112 yvfI K COG2186 Transcriptional regulators
KEPPFGEB_00635 5.7e-308 yvfH C L-lactate permease
KEPPFGEB_00636 1e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KEPPFGEB_00637 1e-31 yvfG S YvfG protein
KEPPFGEB_00638 5.1e-184 yvfF GM Exopolysaccharide biosynthesis protein
KEPPFGEB_00639 2.9e-218 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
KEPPFGEB_00640 4.2e-57 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
KEPPFGEB_00641 5.7e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KEPPFGEB_00642 3.5e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEPPFGEB_00643 2.2e-193 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
KEPPFGEB_00644 4.4e-205 epsI GM pyruvyl transferase
KEPPFGEB_00645 2e-194 epsH GT2 S Glycosyltransferase like family 2
KEPPFGEB_00646 1.1e-206 epsG S EpsG family
KEPPFGEB_00647 3.3e-214 epsF GT4 M Glycosyl transferases group 1
KEPPFGEB_00648 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KEPPFGEB_00649 1.4e-220 epsD GT4 M Glycosyl transferase 4-like
KEPPFGEB_00650 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
KEPPFGEB_00651 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
KEPPFGEB_00652 8.9e-122 ywqC M biosynthesis protein
KEPPFGEB_00653 6.3e-76 slr K transcriptional
KEPPFGEB_00654 7e-286 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KEPPFGEB_00656 4.6e-93 padC Q Phenolic acid decarboxylase
KEPPFGEB_00657 2.2e-73 MA20_18690 S Protein of unknown function (DUF3237)
KEPPFGEB_00658 7.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KEPPFGEB_00659 6.1e-260 pbpE V Beta-lactamase
KEPPFGEB_00660 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
KEPPFGEB_00661 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KEPPFGEB_00662 1.8e-295 yveA E amino acid
KEPPFGEB_00663 2.6e-106 yvdT K Transcriptional regulator
KEPPFGEB_00664 1.5e-50 ykkC P Small Multidrug Resistance protein
KEPPFGEB_00665 4.1e-50 sugE P Small Multidrug Resistance protein
KEPPFGEB_00666 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
KEPPFGEB_00668 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KEPPFGEB_00669 2.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KEPPFGEB_00670 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
KEPPFGEB_00671 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KEPPFGEB_00672 9.8e-158 malA S Protein of unknown function (DUF1189)
KEPPFGEB_00673 6.6e-148 malD P transport
KEPPFGEB_00674 1e-243 malC P COG1175 ABC-type sugar transport systems, permease components
KEPPFGEB_00675 1.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
KEPPFGEB_00676 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
KEPPFGEB_00677 1.7e-171 yvdE K Transcriptional regulator
KEPPFGEB_00678 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
KEPPFGEB_00679 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
KEPPFGEB_00680 2.3e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
KEPPFGEB_00681 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KEPPFGEB_00682 9.6e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KEPPFGEB_00683 0.0 yxdM V ABC transporter (permease)
KEPPFGEB_00684 5.6e-141 yvcR V ABC transporter, ATP-binding protein
KEPPFGEB_00685 5.8e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KEPPFGEB_00686 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEPPFGEB_00687 3.9e-33
KEPPFGEB_00688 1.1e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
KEPPFGEB_00689 1.6e-36 crh G Phosphocarrier protein Chr
KEPPFGEB_00690 1.4e-170 whiA K May be required for sporulation
KEPPFGEB_00691 2.8e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KEPPFGEB_00692 5.7e-166 rapZ S Displays ATPase and GTPase activities
KEPPFGEB_00693 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KEPPFGEB_00694 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KEPPFGEB_00695 2.8e-98 usp CBM50 M protein conserved in bacteria
KEPPFGEB_00696 2.9e-276 S COG0457 FOG TPR repeat
KEPPFGEB_00697 0.0 msbA2 3.6.3.44 V ABC transporter
KEPPFGEB_00699 5.9e-253
KEPPFGEB_00700 8.3e-78
KEPPFGEB_00701 1.4e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KEPPFGEB_00702 3.4e-135 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KEPPFGEB_00703 3.2e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KEPPFGEB_00704 2.8e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KEPPFGEB_00705 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KEPPFGEB_00706 1.7e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KEPPFGEB_00707 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KEPPFGEB_00708 1.2e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KEPPFGEB_00709 1e-139 yvpB NU protein conserved in bacteria
KEPPFGEB_00710 4.8e-117 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
KEPPFGEB_00711 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KEPPFGEB_00712 1.2e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KEPPFGEB_00713 2.2e-160 yvoD P COG0370 Fe2 transport system protein B
KEPPFGEB_00714 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KEPPFGEB_00715 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KEPPFGEB_00716 3.5e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KEPPFGEB_00717 3.3e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KEPPFGEB_00718 1.8e-133 yvoA K transcriptional
KEPPFGEB_00719 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
KEPPFGEB_00720 9.5e-72 adcR K helix_turn_helix multiple antibiotic resistance protein
KEPPFGEB_00721 8.8e-226 cypX 1.14.15.13 C Cytochrome P450
KEPPFGEB_00722 3e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
KEPPFGEB_00723 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
KEPPFGEB_00724 4.7e-203 yvmA EGP Major facilitator Superfamily
KEPPFGEB_00725 1.2e-50 yvlD S Membrane
KEPPFGEB_00726 2.6e-26 pspB KT PspC domain
KEPPFGEB_00727 2.4e-166 yvlB S Putative adhesin
KEPPFGEB_00728 1.8e-48 yvlA
KEPPFGEB_00729 5.7e-33 yvkN
KEPPFGEB_00730 9.2e-78 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KEPPFGEB_00731 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KEPPFGEB_00732 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KEPPFGEB_00733 1.2e-30 csbA S protein conserved in bacteria
KEPPFGEB_00734 0.0 yvkC 2.7.9.2 GT Phosphotransferase
KEPPFGEB_00735 7e-101 yvkB K Transcriptional regulator
KEPPFGEB_00736 8.1e-225 yvkA EGP Major facilitator Superfamily
KEPPFGEB_00737 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KEPPFGEB_00738 5.3e-56 swrA S Swarming motility protein
KEPPFGEB_00739 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KEPPFGEB_00740 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KEPPFGEB_00741 1.6e-123 ftsE D cell division ATP-binding protein FtsE
KEPPFGEB_00742 1e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
KEPPFGEB_00743 2.1e-141 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KEPPFGEB_00744 1e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KEPPFGEB_00745 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KEPPFGEB_00746 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KEPPFGEB_00747 1.8e-65
KEPPFGEB_00748 1.9e-08 fliT S bacterial-type flagellum organization
KEPPFGEB_00749 2.9e-69 fliS N flagellar protein FliS
KEPPFGEB_00750 1.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KEPPFGEB_00751 4.4e-55 flaG N flagellar protein FlaG
KEPPFGEB_00752 1.4e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KEPPFGEB_00753 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KEPPFGEB_00754 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KEPPFGEB_00755 1.3e-49 yviE
KEPPFGEB_00756 1.3e-154 flgL N Belongs to the bacterial flagellin family
KEPPFGEB_00757 2.7e-264 flgK N flagellar hook-associated protein
KEPPFGEB_00758 4.1e-78 flgN NOU FlgN protein
KEPPFGEB_00759 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
KEPPFGEB_00760 7e-74 yvyF S flagellar protein
KEPPFGEB_00761 1.2e-126 comFC S Phosphoribosyl transferase domain
KEPPFGEB_00762 1.1e-44 comFB S Late competence development protein ComFB
KEPPFGEB_00763 6.4e-265 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KEPPFGEB_00764 7.3e-155 degV S protein conserved in bacteria
KEPPFGEB_00765 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEPPFGEB_00766 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KEPPFGEB_00767 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KEPPFGEB_00768 6e-163 yvhJ K Transcriptional regulator
KEPPFGEB_00769 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KEPPFGEB_00770 1.1e-231 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
KEPPFGEB_00771 4.7e-145 tuaG GT2 M Glycosyltransferase like family 2
KEPPFGEB_00772 5.1e-114 tuaF M protein involved in exopolysaccharide biosynthesis
KEPPFGEB_00773 1.1e-262 tuaE M Teichuronic acid biosynthesis protein
KEPPFGEB_00774 6.9e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KEPPFGEB_00775 3.4e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
KEPPFGEB_00776 9.7e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEPPFGEB_00777 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KEPPFGEB_00778 1.5e-94 M Glycosyltransferase like family 2
KEPPFGEB_00779 3.5e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KEPPFGEB_00780 0.0 lytB 3.5.1.28 D Stage II sporulation protein
KEPPFGEB_00781 1e-11
KEPPFGEB_00782 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KEPPFGEB_00783 6.5e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KEPPFGEB_00784 2.1e-88 M Glycosyltransferase like family 2
KEPPFGEB_00785 1.9e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KEPPFGEB_00786 4.8e-23 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KEPPFGEB_00787 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KEPPFGEB_00788 3.1e-271 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KEPPFGEB_00789 1.7e-132 tagG GM Transport permease protein
KEPPFGEB_00790 1.8e-146 M Glycosyl transferases group 1
KEPPFGEB_00791 1.3e-188 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KEPPFGEB_00792 1.2e-142 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KEPPFGEB_00793 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KEPPFGEB_00794 9.2e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KEPPFGEB_00795 2.7e-95 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KEPPFGEB_00796 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
KEPPFGEB_00797 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
KEPPFGEB_00798 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KEPPFGEB_00799 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KEPPFGEB_00800 8.9e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KEPPFGEB_00801 4.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
KEPPFGEB_00802 2.2e-244 gerBA EG Spore germination protein
KEPPFGEB_00803 5.6e-187 gerBB E Spore germination protein
KEPPFGEB_00804 1.1e-198 gerAC S Spore germination protein
KEPPFGEB_00805 1.3e-246 ywtG EGP Major facilitator Superfamily
KEPPFGEB_00806 7e-141 ywtF K Transcriptional regulator
KEPPFGEB_00807 4.2e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
KEPPFGEB_00808 2.7e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KEPPFGEB_00809 3.6e-21 ywtC
KEPPFGEB_00810 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KEPPFGEB_00811 8.6e-70 pgsC S biosynthesis protein
KEPPFGEB_00812 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
KEPPFGEB_00813 9.3e-178 rbsR K transcriptional
KEPPFGEB_00814 1.6e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KEPPFGEB_00815 6.9e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KEPPFGEB_00816 2.1e-274 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KEPPFGEB_00817 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
KEPPFGEB_00818 5.3e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KEPPFGEB_00819 1.5e-92 batE T Sh3 type 3 domain protein
KEPPFGEB_00820 8e-48 ywsA S Protein of unknown function (DUF3892)
KEPPFGEB_00821 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
KEPPFGEB_00822 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KEPPFGEB_00823 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KEPPFGEB_00824 1.1e-169 alsR K LysR substrate binding domain
KEPPFGEB_00825 4.6e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KEPPFGEB_00826 1.4e-124 ywrJ
KEPPFGEB_00827 1.2e-123 cotB
KEPPFGEB_00828 6.2e-207 cotH M Spore Coat
KEPPFGEB_00829 1.3e-12
KEPPFGEB_00830 2.6e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KEPPFGEB_00831 3.5e-52 S Domain of unknown function (DUF4181)
KEPPFGEB_00832 2.3e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KEPPFGEB_00833 8e-82 ywrC K Transcriptional regulator
KEPPFGEB_00834 1.2e-103 ywrB P Chromate transporter
KEPPFGEB_00835 2.4e-87 ywrA P COG2059 Chromate transport protein ChrA
KEPPFGEB_00837 1e-101 ywqN S NAD(P)H-dependent
KEPPFGEB_00838 2.9e-162 K Transcriptional regulator
KEPPFGEB_00839 1.4e-125 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KEPPFGEB_00840 5.9e-72
KEPPFGEB_00841 1.9e-97
KEPPFGEB_00843 5.5e-51
KEPPFGEB_00844 1.1e-75
KEPPFGEB_00845 3.7e-239 ywqJ S Pre-toxin TG
KEPPFGEB_00846 1.3e-38 ywqI S Family of unknown function (DUF5344)
KEPPFGEB_00847 9.7e-23 S Domain of unknown function (DUF5082)
KEPPFGEB_00848 1.3e-153 ywqG S Domain of unknown function (DUF1963)
KEPPFGEB_00849 6.3e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KEPPFGEB_00850 2.5e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KEPPFGEB_00851 2.2e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KEPPFGEB_00852 2e-116 ywqC M biosynthesis protein
KEPPFGEB_00853 1.2e-17
KEPPFGEB_00854 1.7e-306 ywqB S SWIM zinc finger
KEPPFGEB_00855 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KEPPFGEB_00856 2.8e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
KEPPFGEB_00857 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
KEPPFGEB_00858 3.7e-57 ssbB L Single-stranded DNA-binding protein
KEPPFGEB_00859 1.3e-66 ywpG
KEPPFGEB_00860 1.1e-66 ywpF S YwpF-like protein
KEPPFGEB_00861 8.7e-84 srtA 3.4.22.70 M Sortase family
KEPPFGEB_00862 0.0 M1-568 M cell wall anchor domain
KEPPFGEB_00863 3.1e-174 M1-574 T Transcriptional regulatory protein, C terminal
KEPPFGEB_00864 0.0 ywpD T PhoQ Sensor
KEPPFGEB_00865 1.3e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KEPPFGEB_00866 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KEPPFGEB_00867 2e-197 S aspartate phosphatase
KEPPFGEB_00868 2.6e-141 flhP N flagellar basal body
KEPPFGEB_00869 3.4e-125 flhO N flagellar basal body
KEPPFGEB_00870 3.5e-180 mbl D Rod shape-determining protein
KEPPFGEB_00871 3e-44 spoIIID K Stage III sporulation protein D
KEPPFGEB_00872 2.1e-70 ywoH K COG1846 Transcriptional regulators
KEPPFGEB_00873 2.7e-211 ywoG EGP Major facilitator Superfamily
KEPPFGEB_00874 3e-230 ywoF P Right handed beta helix region
KEPPFGEB_00875 1.4e-278 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
KEPPFGEB_00876 1.1e-240 ywoD EGP Major facilitator superfamily
KEPPFGEB_00877 1.2e-103 phzA Q Isochorismatase family
KEPPFGEB_00878 4.8e-76
KEPPFGEB_00879 2.5e-225 amt P Ammonium transporter
KEPPFGEB_00880 1.6e-58 nrgB K Belongs to the P(II) protein family
KEPPFGEB_00881 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KEPPFGEB_00882 3.5e-73 ywnJ S VanZ like family
KEPPFGEB_00883 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KEPPFGEB_00884 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KEPPFGEB_00885 2.7e-14 ywnC S Family of unknown function (DUF5362)
KEPPFGEB_00886 2.2e-70 ywnF S Family of unknown function (DUF5392)
KEPPFGEB_00887 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KEPPFGEB_00888 5.3e-144 mta K transcriptional
KEPPFGEB_00889 1.3e-58 ywnC S Family of unknown function (DUF5362)
KEPPFGEB_00890 1.6e-114 ywnB S NAD(P)H-binding
KEPPFGEB_00891 1.7e-64 ywnA K Transcriptional regulator
KEPPFGEB_00892 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KEPPFGEB_00893 8.5e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KEPPFGEB_00894 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KEPPFGEB_00895 3.8e-11 csbD K CsbD-like
KEPPFGEB_00896 3.8e-84 ywmF S Peptidase M50
KEPPFGEB_00898 4.6e-104 S response regulator aspartate phosphatase
KEPPFGEB_00899 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KEPPFGEB_00900 1.7e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KEPPFGEB_00902 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
KEPPFGEB_00903 3.9e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
KEPPFGEB_00904 4.6e-175 spoIID D Stage II sporulation protein D
KEPPFGEB_00905 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KEPPFGEB_00906 8.2e-134 ywmB S TATA-box binding
KEPPFGEB_00907 1.3e-32 ywzB S membrane
KEPPFGEB_00908 4.3e-88 ywmA
KEPPFGEB_00909 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KEPPFGEB_00910 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KEPPFGEB_00911 1.9e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KEPPFGEB_00912 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KEPPFGEB_00913 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KEPPFGEB_00914 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KEPPFGEB_00915 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KEPPFGEB_00916 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
KEPPFGEB_00917 2.5e-62 atpI S ATP synthase
KEPPFGEB_00918 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KEPPFGEB_00919 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KEPPFGEB_00920 6.1e-94 ywlG S Belongs to the UPF0340 family
KEPPFGEB_00921 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KEPPFGEB_00922 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KEPPFGEB_00923 1.7e-91 mntP P Probably functions as a manganese efflux pump
KEPPFGEB_00924 2.6e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KEPPFGEB_00925 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
KEPPFGEB_00926 3e-111 spoIIR S stage II sporulation protein R
KEPPFGEB_00927 3.7e-55 ywlA S Uncharacterised protein family (UPF0715)
KEPPFGEB_00929 5.8e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KEPPFGEB_00930 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KEPPFGEB_00931 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEPPFGEB_00932 6.4e-75 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KEPPFGEB_00933 8.6e-160 ywkB S Membrane transport protein
KEPPFGEB_00934 0.0 sfcA 1.1.1.38 C malic enzyme
KEPPFGEB_00935 7e-104 tdk 2.7.1.21 F thymidine kinase
KEPPFGEB_00936 1.1e-32 rpmE J Binds the 23S rRNA
KEPPFGEB_00937 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KEPPFGEB_00938 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KEPPFGEB_00939 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KEPPFGEB_00940 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KEPPFGEB_00941 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KEPPFGEB_00942 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
KEPPFGEB_00943 1.8e-90 ywjG S Domain of unknown function (DUF2529)
KEPPFGEB_00944 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KEPPFGEB_00945 5.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KEPPFGEB_00946 7e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
KEPPFGEB_00947 0.0 fadF C COG0247 Fe-S oxidoreductase
KEPPFGEB_00948 4.4e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KEPPFGEB_00949 1.2e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KEPPFGEB_00950 2.7e-42 ywjC
KEPPFGEB_00951 5e-93 ywjB H RibD C-terminal domain
KEPPFGEB_00952 0.0 ywjA V ABC transporter
KEPPFGEB_00953 1.9e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KEPPFGEB_00954 1.5e-123 narI 1.7.5.1 C nitrate reductase, gamma
KEPPFGEB_00955 1.8e-93 narJ 1.7.5.1 C nitrate reductase
KEPPFGEB_00956 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
KEPPFGEB_00957 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KEPPFGEB_00958 4.5e-85 arfM T cyclic nucleotide binding
KEPPFGEB_00959 1.7e-139 ywiC S YwiC-like protein
KEPPFGEB_00960 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
KEPPFGEB_00961 1e-213 narK P COG2223 Nitrate nitrite transporter
KEPPFGEB_00962 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KEPPFGEB_00963 4.7e-73 ywiB S protein conserved in bacteria
KEPPFGEB_00964 1e-07 S Bacteriocin subtilosin A
KEPPFGEB_00965 4.9e-270 C Fe-S oxidoreductases
KEPPFGEB_00967 3.3e-132 cbiO V ABC transporter
KEPPFGEB_00968 8e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
KEPPFGEB_00969 1e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
KEPPFGEB_00970 5e-248 L Peptidase, M16
KEPPFGEB_00972 4.4e-242 ywhL CO amine dehydrogenase activity
KEPPFGEB_00973 1e-190 ywhK CO amine dehydrogenase activity
KEPPFGEB_00974 7.5e-78 S aspartate phosphatase
KEPPFGEB_00976 8.1e-10
KEPPFGEB_00977 1.3e-20
KEPPFGEB_00980 3.4e-59 V ATPases associated with a variety of cellular activities
KEPPFGEB_00982 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
KEPPFGEB_00983 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KEPPFGEB_00984 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KEPPFGEB_00985 2.6e-34
KEPPFGEB_00986 5.2e-95 ywhD S YwhD family
KEPPFGEB_00987 5.1e-119 ywhC S Peptidase family M50
KEPPFGEB_00988 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KEPPFGEB_00989 9.5e-71 ywhA K Transcriptional regulator
KEPPFGEB_00990 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KEPPFGEB_00991 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
KEPPFGEB_00992 7.9e-32 yaaL S Protein of unknown function (DUF2508)
KEPPFGEB_00993 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KEPPFGEB_00994 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KEPPFGEB_00995 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KEPPFGEB_00996 1.6e-82 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KEPPFGEB_00997 1.9e-95 yaaI Q COG1335 Amidases related to nicotinamidase
KEPPFGEB_00998 5.3e-213 yaaH M Glycoside Hydrolase Family
KEPPFGEB_00999 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KEPPFGEB_01000 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KEPPFGEB_01001 1.3e-09
KEPPFGEB_01002 8.1e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KEPPFGEB_01003 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KEPPFGEB_01004 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KEPPFGEB_01005 2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KEPPFGEB_01006 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KEPPFGEB_01007 2.6e-180 yaaC S YaaC-like Protein
KEPPFGEB_01008 2.5e-248 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
KEPPFGEB_01010 1.7e-160 ybaS 1.1.1.58 S Na -dependent transporter
KEPPFGEB_01011 1.2e-137 ybbA S Putative esterase
KEPPFGEB_01012 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEPPFGEB_01013 6.9e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEPPFGEB_01014 4e-165 feuA P Iron-uptake system-binding protein
KEPPFGEB_01015 1.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
KEPPFGEB_01016 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
KEPPFGEB_01017 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KEPPFGEB_01018 3.6e-249 yfeW 3.4.16.4 V Belongs to the UPF0214 family
KEPPFGEB_01019 7e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEPPFGEB_01020 1.2e-149 ybbH K transcriptional
KEPPFGEB_01021 5.1e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KEPPFGEB_01022 1.9e-86 ybbJ J acetyltransferase
KEPPFGEB_01023 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
KEPPFGEB_01029 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KEPPFGEB_01030 6.3e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KEPPFGEB_01031 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KEPPFGEB_01032 3.4e-224 ybbR S protein conserved in bacteria
KEPPFGEB_01033 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KEPPFGEB_01034 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KEPPFGEB_01035 2.1e-171 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KEPPFGEB_01036 3.2e-118 adaA 3.2.2.21 K Transcriptional regulator
KEPPFGEB_01037 2.6e-97 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KEPPFGEB_01038 1.2e-269 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KEPPFGEB_01039 0.0 ybcC S Belongs to the UPF0753 family
KEPPFGEB_01040 2.2e-93 can 4.2.1.1 P carbonic anhydrase
KEPPFGEB_01042 3.3e-46
KEPPFGEB_01043 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
KEPPFGEB_01044 5.1e-50 ybzH K Helix-turn-helix domain
KEPPFGEB_01045 1.9e-201 ybcL EGP Major facilitator Superfamily
KEPPFGEB_01046 7e-56
KEPPFGEB_01047 7.6e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KEPPFGEB_01048 1.3e-122 T Transcriptional regulatory protein, C terminal
KEPPFGEB_01049 2e-167 T His Kinase A (phospho-acceptor) domain
KEPPFGEB_01051 8.8e-139 KLT Protein tyrosine kinase
KEPPFGEB_01052 5.5e-150 ybdN
KEPPFGEB_01053 1.5e-214 ybdO S Domain of unknown function (DUF4885)
KEPPFGEB_01054 9.9e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KEPPFGEB_01055 8.2e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
KEPPFGEB_01056 4.9e-30 ybxH S Family of unknown function (DUF5370)
KEPPFGEB_01057 9.8e-149 ybxI 3.5.2.6 V beta-lactamase
KEPPFGEB_01058 7.8e-246 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KEPPFGEB_01059 4.9e-41 ybyB
KEPPFGEB_01060 1.8e-290 ybeC E amino acid
KEPPFGEB_01061 1.5e-163 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KEPPFGEB_01062 3.6e-257 glpT G -transporter
KEPPFGEB_01063 1.5e-34 S Protein of unknown function (DUF2651)
KEPPFGEB_01064 7.4e-169 ybfA 3.4.15.5 K FR47-like protein
KEPPFGEB_01065 6.7e-221 ybfB G COG0477 Permeases of the major facilitator superfamily
KEPPFGEB_01066 2.2e-157 ybfH EG EamA-like transporter family
KEPPFGEB_01067 2e-144 msmR K AraC-like ligand binding domain
KEPPFGEB_01068 2e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KEPPFGEB_01069 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
KEPPFGEB_01071 1.4e-164 S Alpha/beta hydrolase family
KEPPFGEB_01072 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KEPPFGEB_01073 2.7e-85 ybfM S SNARE associated Golgi protein
KEPPFGEB_01074 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KEPPFGEB_01075 4.6e-45 ybfN
KEPPFGEB_01076 2.1e-252 S Erythromycin esterase
KEPPFGEB_01077 3.3e-191 yceA S Belongs to the UPF0176 family
KEPPFGEB_01078 1.1e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KEPPFGEB_01079 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEPPFGEB_01080 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KEPPFGEB_01081 4.9e-128 K UTRA
KEPPFGEB_01083 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KEPPFGEB_01084 8.2e-260 mmuP E amino acid
KEPPFGEB_01085 2.4e-178 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
KEPPFGEB_01086 2.5e-256 agcS E Sodium alanine symporter
KEPPFGEB_01087 1.2e-185 glsA 3.5.1.2 E Belongs to the glutaminase family
KEPPFGEB_01088 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
KEPPFGEB_01089 1.5e-169 glnL T Regulator
KEPPFGEB_01090 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
KEPPFGEB_01091 1.5e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEPPFGEB_01092 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
KEPPFGEB_01093 2.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KEPPFGEB_01094 2.1e-123 ycbG K FCD
KEPPFGEB_01095 1.7e-295 garD 4.2.1.42, 4.2.1.7 G Altronate
KEPPFGEB_01096 3.7e-176 ycbJ S Macrolide 2'-phosphotransferase
KEPPFGEB_01097 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
KEPPFGEB_01098 1.4e-167 eamA1 EG spore germination
KEPPFGEB_01099 2.5e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEPPFGEB_01100 1.9e-167 T PhoQ Sensor
KEPPFGEB_01101 5e-165 ycbN V ABC transporter, ATP-binding protein
KEPPFGEB_01102 5.1e-114 S ABC-2 family transporter protein
KEPPFGEB_01103 8.2e-53 ycbP S Protein of unknown function (DUF2512)
KEPPFGEB_01104 2.2e-78 sleB 3.5.1.28 M Cell wall
KEPPFGEB_01105 2.5e-135 ycbR T vWA found in TerF C terminus
KEPPFGEB_01106 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
KEPPFGEB_01107 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KEPPFGEB_01108 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KEPPFGEB_01109 3.4e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KEPPFGEB_01110 1.6e-202 ycbU E Selenocysteine lyase
KEPPFGEB_01111 7.9e-226 lmrB EGP the major facilitator superfamily
KEPPFGEB_01112 7e-101 yxaF K Transcriptional regulator
KEPPFGEB_01113 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KEPPFGEB_01114 4.7e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KEPPFGEB_01115 1e-55 S RDD family
KEPPFGEB_01116 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
KEPPFGEB_01117 6.8e-157 2.7.13.3 T GHKL domain
KEPPFGEB_01118 3.9e-125 lytR_2 T LytTr DNA-binding domain
KEPPFGEB_01119 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
KEPPFGEB_01120 1.8e-199 natB CP ABC-2 family transporter protein
KEPPFGEB_01121 5e-173 yccK C Aldo keto reductase
KEPPFGEB_01122 6.6e-177 ycdA S Domain of unknown function (DUF5105)
KEPPFGEB_01123 4.4e-269 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
KEPPFGEB_01124 1.2e-264 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
KEPPFGEB_01125 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
KEPPFGEB_01126 1.2e-173 S response regulator aspartate phosphatase
KEPPFGEB_01127 1.8e-139 IQ Enoyl-(Acyl carrier protein) reductase
KEPPFGEB_01128 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KEPPFGEB_01129 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
KEPPFGEB_01130 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KEPPFGEB_01131 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KEPPFGEB_01132 1.3e-182 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEPPFGEB_01133 2.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
KEPPFGEB_01134 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
KEPPFGEB_01135 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
KEPPFGEB_01136 6.3e-137 terC P Protein of unknown function (DUF475)
KEPPFGEB_01137 0.0 yceG S Putative component of 'biosynthetic module'
KEPPFGEB_01138 2e-192 yceH P Belongs to the TelA family
KEPPFGEB_01139 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
KEPPFGEB_01140 2.4e-204 yceJ EGP Uncharacterised MFS-type transporter YbfB
KEPPFGEB_01141 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
KEPPFGEB_01142 4.3e-228 proV 3.6.3.32 E glycine betaine
KEPPFGEB_01143 1.3e-127 opuAB P glycine betaine
KEPPFGEB_01144 5.3e-164 opuAC E glycine betaine
KEPPFGEB_01145 5e-215 amhX S amidohydrolase
KEPPFGEB_01146 5.6e-256 ycgA S Membrane
KEPPFGEB_01147 1.2e-80 ycgB
KEPPFGEB_01148 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
KEPPFGEB_01149 9.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KEPPFGEB_01150 6.5e-293 lctP C L-lactate permease
KEPPFGEB_01151 3.9e-263 mdr EGP Major facilitator Superfamily
KEPPFGEB_01152 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
KEPPFGEB_01153 6.8e-113 ycgF E Lysine exporter protein LysE YggA
KEPPFGEB_01154 2.4e-149 yqcI S YqcI/YcgG family
KEPPFGEB_01155 2.1e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KEPPFGEB_01156 7.1e-112 ycgI S Domain of unknown function (DUF1989)
KEPPFGEB_01157 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KEPPFGEB_01158 3.1e-107 tmrB S AAA domain
KEPPFGEB_01160 9.6e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KEPPFGEB_01161 1.3e-142 yafE Q ubiE/COQ5 methyltransferase family
KEPPFGEB_01162 3.2e-178 oxyR3 K LysR substrate binding domain
KEPPFGEB_01163 2.1e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KEPPFGEB_01164 2.4e-144 ycgL S Predicted nucleotidyltransferase
KEPPFGEB_01165 5.1e-170 ycgM E Proline dehydrogenase
KEPPFGEB_01166 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KEPPFGEB_01167 2e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEPPFGEB_01168 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
KEPPFGEB_01169 2.2e-146 ycgQ S membrane
KEPPFGEB_01170 1.2e-139 ycgR S permeases
KEPPFGEB_01171 5.9e-160 I alpha/beta hydrolase fold
KEPPFGEB_01172 9.3e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KEPPFGEB_01173 7.6e-277 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KEPPFGEB_01174 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
KEPPFGEB_01175 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KEPPFGEB_01176 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KEPPFGEB_01177 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
KEPPFGEB_01178 8.4e-221 nasA P COG2223 Nitrate nitrite transporter
KEPPFGEB_01179 1.1e-169 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
KEPPFGEB_01180 2.5e-98 yciB M ErfK YbiS YcfS YnhG
KEPPFGEB_01181 5.9e-227 yciC S GTPases (G3E family)
KEPPFGEB_01182 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
KEPPFGEB_01183 4e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KEPPFGEB_01185 5.3e-75 yckC S membrane
KEPPFGEB_01186 1.1e-50 yckD S Protein of unknown function (DUF2680)
KEPPFGEB_01187 4.1e-45 K MarR family
KEPPFGEB_01188 9.3e-24
KEPPFGEB_01189 2.7e-121 S AAA domain
KEPPFGEB_01190 6.1e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KEPPFGEB_01191 6.5e-69 nin S Competence protein J (ComJ)
KEPPFGEB_01192 1.3e-70 nucA M Deoxyribonuclease NucA/NucB
KEPPFGEB_01193 1e-179 tlpC 2.7.13.3 NT chemotaxis protein
KEPPFGEB_01194 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
KEPPFGEB_01195 8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
KEPPFGEB_01196 1.3e-63 hxlR K transcriptional
KEPPFGEB_01197 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEPPFGEB_01198 3.4e-39 S COG NOG14552 non supervised orthologous group
KEPPFGEB_01199 4.5e-12 S ORF located using Blastx
KEPPFGEB_01200 5.4e-149 yqcI S YqcI/YcgG family
KEPPFGEB_01201 1.6e-54 arsR K ArsR family transcriptional regulator
KEPPFGEB_01202 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEPPFGEB_01203 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
KEPPFGEB_01204 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
KEPPFGEB_01205 1.4e-281 cisA2 L Recombinase
KEPPFGEB_01206 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEPPFGEB_01207 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
KEPPFGEB_01208 4.1e-130 yqeB
KEPPFGEB_01209 1.2e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
KEPPFGEB_01210 1.8e-105 yqeD S SNARE associated Golgi protein
KEPPFGEB_01211 4.1e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KEPPFGEB_01212 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
KEPPFGEB_01214 5.3e-95 yqeG S hydrolase of the HAD superfamily
KEPPFGEB_01215 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KEPPFGEB_01216 2.3e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KEPPFGEB_01217 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KEPPFGEB_01218 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KEPPFGEB_01219 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KEPPFGEB_01220 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KEPPFGEB_01221 3.2e-138 yqeM Q Methyltransferase
KEPPFGEB_01222 2.1e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KEPPFGEB_01223 6.2e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
KEPPFGEB_01224 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
KEPPFGEB_01225 0.0 comEC S Competence protein ComEC
KEPPFGEB_01226 4.1e-15 S YqzM-like protein
KEPPFGEB_01227 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
KEPPFGEB_01228 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
KEPPFGEB_01229 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KEPPFGEB_01230 1.5e-222 spoIIP M stage II sporulation protein P
KEPPFGEB_01231 4.7e-52 yqxA S Protein of unknown function (DUF3679)
KEPPFGEB_01232 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KEPPFGEB_01233 1.9e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
KEPPFGEB_01234 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KEPPFGEB_01235 6.1e-73 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KEPPFGEB_01236 0.0 dnaK O Heat shock 70 kDa protein
KEPPFGEB_01237 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KEPPFGEB_01238 3e-173 prmA J Methylates ribosomal protein L11
KEPPFGEB_01239 3e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KEPPFGEB_01240 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KEPPFGEB_01241 4.1e-157 yqeW P COG1283 Na phosphate symporter
KEPPFGEB_01242 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KEPPFGEB_01243 2.5e-61 yqeY S Yqey-like protein
KEPPFGEB_01244 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
KEPPFGEB_01245 4.3e-122 yqfA S UPF0365 protein
KEPPFGEB_01246 5.1e-24 yqfB
KEPPFGEB_01247 2.7e-45 yqfC S sporulation protein YqfC
KEPPFGEB_01248 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KEPPFGEB_01249 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
KEPPFGEB_01251 0.0 yqfF S membrane-associated HD superfamily hydrolase
KEPPFGEB_01252 6.7e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KEPPFGEB_01253 3e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KEPPFGEB_01254 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KEPPFGEB_01255 6.9e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KEPPFGEB_01256 8.4e-19 S YqzL-like protein
KEPPFGEB_01257 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
KEPPFGEB_01258 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KEPPFGEB_01259 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KEPPFGEB_01260 4.5e-112 ccpN K CBS domain
KEPPFGEB_01261 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KEPPFGEB_01262 4.5e-88 yaiI S Belongs to the UPF0178 family
KEPPFGEB_01263 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KEPPFGEB_01264 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KEPPFGEB_01265 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
KEPPFGEB_01266 1.5e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
KEPPFGEB_01267 1.9e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KEPPFGEB_01268 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KEPPFGEB_01269 3.5e-12 yqfQ S YqfQ-like protein
KEPPFGEB_01270 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KEPPFGEB_01271 4.4e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KEPPFGEB_01272 2.1e-36 yqfT S Protein of unknown function (DUF2624)
KEPPFGEB_01273 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KEPPFGEB_01274 4.2e-77 zur P Belongs to the Fur family
KEPPFGEB_01275 1e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KEPPFGEB_01276 4.3e-62 yqfX S membrane
KEPPFGEB_01277 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KEPPFGEB_01278 5.2e-47 yqfZ M LysM domain
KEPPFGEB_01279 3.9e-131 yqgB S Protein of unknown function (DUF1189)
KEPPFGEB_01280 4e-73 yqgC S protein conserved in bacteria
KEPPFGEB_01281 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KEPPFGEB_01282 2.5e-231 yqgE EGP Major facilitator superfamily
KEPPFGEB_01283 0.0 pbpA 3.4.16.4 M penicillin-binding protein
KEPPFGEB_01284 6.2e-144 pstS P Phosphate
KEPPFGEB_01285 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
KEPPFGEB_01286 4.4e-158 pstA P Phosphate transport system permease
KEPPFGEB_01287 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KEPPFGEB_01288 1.9e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KEPPFGEB_01289 1.9e-75 yqzC S YceG-like family
KEPPFGEB_01290 9.2e-51 yqzD
KEPPFGEB_01292 2.3e-196 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
KEPPFGEB_01293 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KEPPFGEB_01294 7.4e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KEPPFGEB_01295 2.5e-09 yqgO
KEPPFGEB_01296 4e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KEPPFGEB_01297 3.1e-33 yqgQ S Protein conserved in bacteria
KEPPFGEB_01298 5.2e-181 glcK 2.7.1.2 G Glucokinase
KEPPFGEB_01299 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KEPPFGEB_01300 7.9e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
KEPPFGEB_01301 1.3e-196 yqgU
KEPPFGEB_01302 6.9e-50 yqgV S Thiamine-binding protein
KEPPFGEB_01303 8.9e-23 yqgW S Protein of unknown function (DUF2759)
KEPPFGEB_01304 8e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KEPPFGEB_01305 1.8e-37 yqgY S Protein of unknown function (DUF2626)
KEPPFGEB_01306 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
KEPPFGEB_01308 8.6e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KEPPFGEB_01309 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KEPPFGEB_01310 7.2e-175 corA P Mg2 transporter protein
KEPPFGEB_01312 1.1e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KEPPFGEB_01313 6.9e-171 comGB NU COG1459 Type II secretory pathway, component PulF
KEPPFGEB_01314 1.5e-46 comGC U Required for transformation and DNA binding
KEPPFGEB_01315 4.9e-70 gspH NU protein transport across the cell outer membrane
KEPPFGEB_01316 4.5e-58 comGE
KEPPFGEB_01317 1.7e-34 comGF U Putative Competence protein ComGF
KEPPFGEB_01318 1.2e-43 S ComG operon protein 7
KEPPFGEB_01319 5.2e-26 yqzE S YqzE-like protein
KEPPFGEB_01320 1.2e-52 yqzG S Protein of unknown function (DUF3889)
KEPPFGEB_01321 1e-110 yqxM
KEPPFGEB_01322 6.7e-59 sipW 3.4.21.89 U Signal peptidase
KEPPFGEB_01323 8.6e-142 tasA S Cell division protein FtsN
KEPPFGEB_01324 1e-54 sinR K transcriptional
KEPPFGEB_01325 3.6e-24 sinI S Anti-repressor SinI
KEPPFGEB_01326 1e-150 yqhG S Bacterial protein YqhG of unknown function
KEPPFGEB_01327 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KEPPFGEB_01328 3.7e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KEPPFGEB_01329 9.3e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KEPPFGEB_01330 2.2e-284 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KEPPFGEB_01331 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
KEPPFGEB_01332 7.5e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KEPPFGEB_01333 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KEPPFGEB_01334 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
KEPPFGEB_01335 2.2e-61 yqhP
KEPPFGEB_01336 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
KEPPFGEB_01337 2.3e-93 yqhR S Conserved membrane protein YqhR
KEPPFGEB_01338 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KEPPFGEB_01339 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KEPPFGEB_01340 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KEPPFGEB_01341 7.9e-37 yqhV S Protein of unknown function (DUF2619)
KEPPFGEB_01342 4e-170 spoIIIAA S stage III sporulation protein AA
KEPPFGEB_01343 1.1e-84 spoIIIAB S Stage III sporulation protein
KEPPFGEB_01344 7.6e-29 spoIIIAC S stage III sporulation protein AC
KEPPFGEB_01345 2.3e-58 spoIIIAD S Stage III sporulation protein AD
KEPPFGEB_01346 1.4e-196 spoIIIAE S stage III sporulation protein AE
KEPPFGEB_01347 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
KEPPFGEB_01348 2.2e-109 spoIIIAG S stage III sporulation protein AG
KEPPFGEB_01349 9.9e-91 spoIIIAH S SpoIIIAH-like protein
KEPPFGEB_01350 1.1e-62 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KEPPFGEB_01351 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KEPPFGEB_01352 2.1e-67 yqhY S protein conserved in bacteria
KEPPFGEB_01353 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KEPPFGEB_01354 5.1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KEPPFGEB_01355 8.4e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KEPPFGEB_01356 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KEPPFGEB_01357 6.5e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KEPPFGEB_01358 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KEPPFGEB_01359 1.9e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KEPPFGEB_01360 5.6e-77 argR K Regulates arginine biosynthesis genes
KEPPFGEB_01361 6e-305 recN L May be involved in recombinational repair of damaged DNA
KEPPFGEB_01362 4.4e-236 rseP 3.4.21.116 M Stage IV sporulation protein B
KEPPFGEB_01363 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KEPPFGEB_01365 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KEPPFGEB_01366 5.9e-27
KEPPFGEB_01367 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
KEPPFGEB_01368 1.4e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KEPPFGEB_01369 1e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
KEPPFGEB_01370 5.7e-155 hbdA 1.1.1.157 I Dehydrogenase
KEPPFGEB_01371 2e-211 mmgC I acyl-CoA dehydrogenase
KEPPFGEB_01372 1.4e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KEPPFGEB_01373 1.2e-274 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KEPPFGEB_01374 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KEPPFGEB_01375 8.9e-34 yqzF S Protein of unknown function (DUF2627)
KEPPFGEB_01376 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
KEPPFGEB_01377 2.1e-155 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
KEPPFGEB_01378 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KEPPFGEB_01379 3.5e-202 buk 2.7.2.7 C Belongs to the acetokinase family
KEPPFGEB_01380 2.2e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KEPPFGEB_01381 2.5e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KEPPFGEB_01382 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KEPPFGEB_01383 2.6e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KEPPFGEB_01384 5.8e-152 bmrR K helix_turn_helix, mercury resistance
KEPPFGEB_01385 5.1e-207 norA EGP Major facilitator Superfamily
KEPPFGEB_01386 1.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KEPPFGEB_01387 9.3e-77 yqiW S Belongs to the UPF0403 family
KEPPFGEB_01388 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
KEPPFGEB_01389 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
KEPPFGEB_01390 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KEPPFGEB_01391 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
KEPPFGEB_01392 3.4e-97 yqjB S protein conserved in bacteria
KEPPFGEB_01394 3e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
KEPPFGEB_01395 4.5e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KEPPFGEB_01396 6.2e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KEPPFGEB_01397 2.7e-137 yqjF S Uncharacterized conserved protein (COG2071)
KEPPFGEB_01398 5.5e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KEPPFGEB_01399 3.4e-24 yqzJ
KEPPFGEB_01400 1.8e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KEPPFGEB_01401 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KEPPFGEB_01402 4.8e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KEPPFGEB_01403 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KEPPFGEB_01404 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KEPPFGEB_01405 1.1e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KEPPFGEB_01406 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KEPPFGEB_01407 0.0 rocB E arginine degradation protein
KEPPFGEB_01408 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KEPPFGEB_01409 8.3e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
KEPPFGEB_01410 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KEPPFGEB_01411 2.1e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
KEPPFGEB_01412 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
KEPPFGEB_01413 5.7e-70 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEPPFGEB_01415 1.1e-220 yqjV G Major Facilitator Superfamily
KEPPFGEB_01417 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KEPPFGEB_01418 5.7e-50 S YolD-like protein
KEPPFGEB_01419 3.6e-87 yqjY K acetyltransferase
KEPPFGEB_01420 6.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
KEPPFGEB_01421 2.2e-193 yqkA K GrpB protein
KEPPFGEB_01422 2.8e-54 yqkB S Belongs to the HesB IscA family
KEPPFGEB_01423 9.4e-39 yqkC S Protein of unknown function (DUF2552)
KEPPFGEB_01424 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KEPPFGEB_01425 3.1e-12 yqkE S Protein of unknown function (DUF3886)
KEPPFGEB_01426 9.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KEPPFGEB_01428 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KEPPFGEB_01429 1.8e-220 yqxK 3.6.4.12 L DNA helicase
KEPPFGEB_01430 4.5e-58 ansR K Transcriptional regulator
KEPPFGEB_01431 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
KEPPFGEB_01432 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
KEPPFGEB_01433 9.1e-235 mleN C Na H antiporter
KEPPFGEB_01434 5.5e-242 mleA 1.1.1.38 C malic enzyme
KEPPFGEB_01435 5e-30 yqkK
KEPPFGEB_01436 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KEPPFGEB_01437 2.4e-80 fur P Belongs to the Fur family
KEPPFGEB_01438 3.7e-37 S Protein of unknown function (DUF4227)
KEPPFGEB_01439 3.7e-165 xerD L recombinase XerD
KEPPFGEB_01440 1.3e-229 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KEPPFGEB_01441 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KEPPFGEB_01442 6.3e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KEPPFGEB_01443 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KEPPFGEB_01444 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KEPPFGEB_01445 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEPPFGEB_01446 1.4e-110 spoVAA S Stage V sporulation protein AA
KEPPFGEB_01447 1e-67 spoVAB S Stage V sporulation protein AB
KEPPFGEB_01448 2.3e-78 spoVAC S stage V sporulation protein AC
KEPPFGEB_01449 9e-192 spoVAD I Stage V sporulation protein AD
KEPPFGEB_01450 2.2e-57 spoVAEB S stage V sporulation protein
KEPPFGEB_01451 1.4e-110 spoVAEA S stage V sporulation protein
KEPPFGEB_01452 1.4e-273 spoVAF EG Stage V sporulation protein AF
KEPPFGEB_01453 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KEPPFGEB_01454 8.1e-149 ypuA S Secreted protein
KEPPFGEB_01455 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KEPPFGEB_01457 3.6e-31 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
KEPPFGEB_01458 6.4e-99 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KEPPFGEB_01459 7.8e-55 ypuD
KEPPFGEB_01460 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KEPPFGEB_01461 5.7e-115 ribE 2.5.1.9 H Riboflavin synthase
KEPPFGEB_01462 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KEPPFGEB_01463 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KEPPFGEB_01464 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEPPFGEB_01465 9.4e-92 ypuF S Domain of unknown function (DUF309)
KEPPFGEB_01466 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KEPPFGEB_01467 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KEPPFGEB_01468 7.6e-97 ypuI S Protein of unknown function (DUF3907)
KEPPFGEB_01469 4e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KEPPFGEB_01470 3.5e-103 spmA S Spore maturation protein
KEPPFGEB_01471 1.9e-87 spmB S Spore maturation protein
KEPPFGEB_01472 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KEPPFGEB_01473 1.6e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KEPPFGEB_01474 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KEPPFGEB_01475 5.1e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KEPPFGEB_01476 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEPPFGEB_01477 0.0 resE 2.7.13.3 T Histidine kinase
KEPPFGEB_01478 1e-102 sigX K Belongs to the sigma-70 factor family. ECF subfamily
KEPPFGEB_01479 1.3e-188 rsiX
KEPPFGEB_01480 4.6e-132 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KEPPFGEB_01481 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KEPPFGEB_01482 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KEPPFGEB_01483 4.7e-41 fer C Ferredoxin
KEPPFGEB_01484 1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
KEPPFGEB_01485 3.5e-285 recQ 3.6.4.12 L DNA helicase
KEPPFGEB_01486 1.1e-99 ypbD S metal-dependent membrane protease
KEPPFGEB_01487 1.7e-78 ypbE M Lysin motif
KEPPFGEB_01488 2.8e-81 ypbF S Protein of unknown function (DUF2663)
KEPPFGEB_01489 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
KEPPFGEB_01490 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KEPPFGEB_01491 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KEPPFGEB_01492 5.6e-175 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KEPPFGEB_01493 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
KEPPFGEB_01494 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KEPPFGEB_01495 5.5e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KEPPFGEB_01496 3.9e-111 ypfA M Flagellar protein YcgR
KEPPFGEB_01497 2.4e-23 S Family of unknown function (DUF5359)
KEPPFGEB_01498 6.8e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KEPPFGEB_01499 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
KEPPFGEB_01500 1.2e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KEPPFGEB_01501 8e-08 S YpzI-like protein
KEPPFGEB_01502 2.3e-102 yphA
KEPPFGEB_01503 2.5e-161 seaA S YIEGIA protein
KEPPFGEB_01504 2.3e-27 ypzH
KEPPFGEB_01505 1.5e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KEPPFGEB_01506 3.6e-180 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KEPPFGEB_01507 2e-18 yphE S Protein of unknown function (DUF2768)
KEPPFGEB_01508 6e-137 yphF
KEPPFGEB_01509 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KEPPFGEB_01510 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KEPPFGEB_01511 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
KEPPFGEB_01512 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KEPPFGEB_01513 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KEPPFGEB_01514 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KEPPFGEB_01515 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KEPPFGEB_01516 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KEPPFGEB_01517 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KEPPFGEB_01518 2.1e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KEPPFGEB_01519 2e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KEPPFGEB_01520 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KEPPFGEB_01521 1.4e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KEPPFGEB_01522 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KEPPFGEB_01523 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KEPPFGEB_01524 1.5e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
KEPPFGEB_01525 7.6e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KEPPFGEB_01526 1e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KEPPFGEB_01527 7.8e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KEPPFGEB_01528 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KEPPFGEB_01529 1.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KEPPFGEB_01530 5.9e-233 S COG0457 FOG TPR repeat
KEPPFGEB_01531 1.1e-98 ypiB S Belongs to the UPF0302 family
KEPPFGEB_01532 4.2e-77 ypiF S Protein of unknown function (DUF2487)
KEPPFGEB_01533 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
KEPPFGEB_01534 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
KEPPFGEB_01535 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KEPPFGEB_01536 9.9e-98 ypjA S membrane
KEPPFGEB_01537 1e-142 ypjB S sporulation protein
KEPPFGEB_01538 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KEPPFGEB_01539 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KEPPFGEB_01540 1.2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KEPPFGEB_01541 1.6e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KEPPFGEB_01542 3.4e-129 bshB1 S proteins, LmbE homologs
KEPPFGEB_01543 4.5e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KEPPFGEB_01544 1.1e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KEPPFGEB_01545 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KEPPFGEB_01546 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KEPPFGEB_01547 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KEPPFGEB_01548 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KEPPFGEB_01549 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KEPPFGEB_01550 6.7e-23 ypmA S Protein of unknown function (DUF4264)
KEPPFGEB_01551 2.2e-79 ypmB S protein conserved in bacteria
KEPPFGEB_01552 1.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KEPPFGEB_01553 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
KEPPFGEB_01554 5.7e-129 dnaD L DNA replication protein DnaD
KEPPFGEB_01555 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KEPPFGEB_01556 5.2e-92 ypoC
KEPPFGEB_01557 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
KEPPFGEB_01558 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KEPPFGEB_01559 7.7e-185 yppC S Protein of unknown function (DUF2515)
KEPPFGEB_01562 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
KEPPFGEB_01564 1.2e-48 yppG S YppG-like protein
KEPPFGEB_01565 1.2e-70 hspX O Belongs to the small heat shock protein (HSP20) family
KEPPFGEB_01566 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KEPPFGEB_01567 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KEPPFGEB_01568 4.3e-236 yprB L RNase_H superfamily
KEPPFGEB_01569 2.8e-91 ypsA S Belongs to the UPF0398 family
KEPPFGEB_01570 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KEPPFGEB_01571 1.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KEPPFGEB_01573 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
KEPPFGEB_01574 1.8e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEPPFGEB_01575 6.3e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KEPPFGEB_01576 1.3e-185 ptxS K transcriptional
KEPPFGEB_01577 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KEPPFGEB_01578 1.7e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KEPPFGEB_01579 4.3e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
KEPPFGEB_01580 1.9e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KEPPFGEB_01581 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KEPPFGEB_01582 7.8e-228 pbuX F xanthine
KEPPFGEB_01583 1.4e-206 bcsA Q Naringenin-chalcone synthase
KEPPFGEB_01584 6.7e-87 ypbQ S protein conserved in bacteria
KEPPFGEB_01586 0.0 ypbR S Dynamin family
KEPPFGEB_01587 1e-38 ypbS S Protein of unknown function (DUF2533)
KEPPFGEB_01588 2e-07
KEPPFGEB_01589 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
KEPPFGEB_01591 2.1e-67 rnhA 3.1.26.4 L Ribonuclease
KEPPFGEB_01592 1e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KEPPFGEB_01593 4.7e-135 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
KEPPFGEB_01594 3e-29 ypeQ S Zinc-finger
KEPPFGEB_01595 8.1e-31 S Protein of unknown function (DUF2564)
KEPPFGEB_01596 3.8e-16 degR
KEPPFGEB_01597 7.9e-31 cspD K Cold-shock protein
KEPPFGEB_01598 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KEPPFGEB_01600 8.1e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KEPPFGEB_01601 1.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KEPPFGEB_01602 1.3e-103 ypgQ S phosphohydrolase
KEPPFGEB_01603 5.8e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
KEPPFGEB_01604 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KEPPFGEB_01605 1.7e-75 yphP S Belongs to the UPF0403 family
KEPPFGEB_01606 1e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
KEPPFGEB_01607 2.5e-112 ypjP S YpjP-like protein
KEPPFGEB_01608 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KEPPFGEB_01609 6.9e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KEPPFGEB_01610 5.7e-94 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KEPPFGEB_01611 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KEPPFGEB_01612 4.2e-110 hlyIII S protein, Hemolysin III
KEPPFGEB_01613 1.1e-181 pspF K Transcriptional regulator
KEPPFGEB_01614 3.5e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KEPPFGEB_01615 8.9e-40 ypmP S Protein of unknown function (DUF2535)
KEPPFGEB_01616 4.6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KEPPFGEB_01617 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
KEPPFGEB_01618 1.1e-98 ypmS S protein conserved in bacteria
KEPPFGEB_01619 1.2e-28 ypmT S Uncharacterized ympT
KEPPFGEB_01620 1.7e-222 mepA V MATE efflux family protein
KEPPFGEB_01621 1.6e-70 ypoP K transcriptional
KEPPFGEB_01622 1.3e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KEPPFGEB_01623 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KEPPFGEB_01624 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
KEPPFGEB_01625 5.8e-211 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
KEPPFGEB_01626 8.8e-181 cgeB S Spore maturation protein
KEPPFGEB_01627 8.2e-64 cgeA
KEPPFGEB_01628 1.4e-36 cgeC
KEPPFGEB_01629 8.5e-256 cgeD M maturation of the outermost layer of the spore
KEPPFGEB_01630 4.1e-144 yiiD K acetyltransferase
KEPPFGEB_01632 1.5e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KEPPFGEB_01633 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KEPPFGEB_01634 2.3e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KEPPFGEB_01635 4.6e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
KEPPFGEB_01636 2.3e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
KEPPFGEB_01637 3.9e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
KEPPFGEB_01638 2.9e-47 yokU S YokU-like protein, putative antitoxin
KEPPFGEB_01639 1.4e-36 yozE S Belongs to the UPF0346 family
KEPPFGEB_01640 6e-123 yodN
KEPPFGEB_01642 2.8e-24 yozD S YozD-like protein
KEPPFGEB_01643 2e-106 yodM 3.6.1.27 I Acid phosphatase homologues
KEPPFGEB_01644 3.6e-54 yodL S YodL-like
KEPPFGEB_01645 5.3e-09
KEPPFGEB_01646 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KEPPFGEB_01647 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KEPPFGEB_01648 1.5e-23 yodI
KEPPFGEB_01649 6.3e-128 yodH Q Methyltransferase
KEPPFGEB_01650 9.7e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KEPPFGEB_01651 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEPPFGEB_01652 6.2e-28 S Protein of unknown function (DUF3311)
KEPPFGEB_01653 7.9e-171 yodE E COG0346 Lactoylglutathione lyase and related lyases
KEPPFGEB_01654 2.1e-111 mhqD S Carboxylesterase
KEPPFGEB_01655 1.4e-107 yodC C nitroreductase
KEPPFGEB_01656 4.4e-55 yodB K transcriptional
KEPPFGEB_01657 4.7e-64 yodA S tautomerase
KEPPFGEB_01658 1.7e-128 gntP EG COG2610 H gluconate symporter and related permeases
KEPPFGEB_01659 4.4e-59 gntP EG COG2610 H gluconate symporter and related permeases
KEPPFGEB_01660 3.4e-09
KEPPFGEB_01661 1.2e-58 yozR S COG0071 Molecular chaperone (small heat shock protein)
KEPPFGEB_01662 5.6e-161 rarD S -transporter
KEPPFGEB_01663 3.3e-43
KEPPFGEB_01664 2.2e-60 yojF S Protein of unknown function (DUF1806)
KEPPFGEB_01665 2.1e-125 yojG S deacetylase
KEPPFGEB_01666 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KEPPFGEB_01667 3.6e-244 norM V Multidrug efflux pump
KEPPFGEB_01669 7.6e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KEPPFGEB_01670 5.3e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
KEPPFGEB_01671 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KEPPFGEB_01672 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KEPPFGEB_01673 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
KEPPFGEB_01674 0.0 yojO P Von Willebrand factor
KEPPFGEB_01675 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KEPPFGEB_01676 1.6e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KEPPFGEB_01677 8.6e-168 yocS S -transporter
KEPPFGEB_01678 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KEPPFGEB_01679 6e-165 sodA 1.15.1.1 P Superoxide dismutase
KEPPFGEB_01680 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KEPPFGEB_01681 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KEPPFGEB_01682 2.7e-31 yozC
KEPPFGEB_01683 4.2e-56 yozO S Bacterial PH domain
KEPPFGEB_01684 1.9e-36 yocN
KEPPFGEB_01685 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
KEPPFGEB_01686 6.2e-32
KEPPFGEB_01687 5.4e-53 yocL
KEPPFGEB_01688 3.3e-83 dksA T general stress protein
KEPPFGEB_01689 2.3e-113 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KEPPFGEB_01690 0.0 recQ 3.6.4.12 L DNA helicase
KEPPFGEB_01691 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
KEPPFGEB_01692 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEPPFGEB_01693 7.1e-198 desK 2.7.13.3 T Histidine kinase
KEPPFGEB_01694 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KEPPFGEB_01695 9.3e-186 yocD 3.4.17.13 V peptidase S66
KEPPFGEB_01696 6.1e-93 yocC
KEPPFGEB_01697 6.4e-145
KEPPFGEB_01698 1.5e-92 yozB S membrane
KEPPFGEB_01699 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KEPPFGEB_01700 1e-51 czrA K transcriptional
KEPPFGEB_01701 1e-93 yobW
KEPPFGEB_01702 2.8e-171 yobV K WYL domain
KEPPFGEB_01703 7.1e-86 yobU K Bacterial transcription activator, effector binding domain
KEPPFGEB_01704 4.7e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
KEPPFGEB_01705 3.6e-97 yobS K Transcriptional regulator
KEPPFGEB_01706 5.3e-141 yobR 2.3.1.1 J FR47-like protein
KEPPFGEB_01707 4e-133 yobQ K helix_turn_helix, arabinose operon control protein
KEPPFGEB_01708 1.9e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
KEPPFGEB_01709 2e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
KEPPFGEB_01710 4.1e-101 yokH G SMI1 / KNR4 family
KEPPFGEB_01711 4.9e-118 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KEPPFGEB_01712 1.6e-166 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KEPPFGEB_01713 3.3e-85 S SMI1-KNR4 cell-wall
KEPPFGEB_01714 2.8e-47
KEPPFGEB_01716 6.4e-11 S YolD-like protein
KEPPFGEB_01717 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
KEPPFGEB_01718 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
KEPPFGEB_01721 9.1e-167 bla 3.5.2.6 V beta-lactamase
KEPPFGEB_01722 7.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KEPPFGEB_01723 1.2e-76 yoaW
KEPPFGEB_01724 1.8e-159 yijE EG EamA-like transporter family
KEPPFGEB_01725 3.3e-158 yoaU K LysR substrate binding domain
KEPPFGEB_01726 6.3e-148 yoaT S Protein of unknown function (DUF817)
KEPPFGEB_01727 2.2e-29 yozG K Transcriptional regulator
KEPPFGEB_01728 7.3e-75 yoaS S Protein of unknown function (DUF2975)
KEPPFGEB_01729 2.7e-171 yoaR V vancomycin resistance protein
KEPPFGEB_01730 5e-87
KEPPFGEB_01733 3.9e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
KEPPFGEB_01736 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
KEPPFGEB_01737 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
KEPPFGEB_01738 2.3e-111 yoaK S Membrane
KEPPFGEB_01739 3.2e-132 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
KEPPFGEB_01740 2.1e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
KEPPFGEB_01741 9.4e-178 mcpU NT methyl-accepting chemotaxis protein
KEPPFGEB_01742 7.7e-35 S Protein of unknown function (DUF4025)
KEPPFGEB_01743 7e-14
KEPPFGEB_01744 2.2e-07
KEPPFGEB_01745 3.3e-90 purR K Transcriptional regulator
KEPPFGEB_01746 1.6e-150 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
KEPPFGEB_01747 6.3e-205 S Oxidoreductase family, C-terminal alpha/beta domain
KEPPFGEB_01748 1.5e-171 iolT EGP Major facilitator Superfamily
KEPPFGEB_01749 8.7e-32 yoaF
KEPPFGEB_01750 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KEPPFGEB_01751 5.8e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KEPPFGEB_01752 1e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
KEPPFGEB_01753 9.9e-233 yoaB EGP Major facilitator Superfamily
KEPPFGEB_01754 6.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
KEPPFGEB_01755 4.8e-139 V AAA domain, putative AbiEii toxin, Type IV TA system
KEPPFGEB_01756 6.4e-94 V ABC-2 family transporter protein
KEPPFGEB_01757 1.4e-125 V ABC-2 family transporter protein
KEPPFGEB_01758 4.1e-95 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KEPPFGEB_01759 3.6e-132 yoxB
KEPPFGEB_01760 9.2e-39 yoxC S Bacterial protein of unknown function (DUF948)
KEPPFGEB_01761 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KEPPFGEB_01762 2.5e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KEPPFGEB_01763 7.3e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KEPPFGEB_01764 1.5e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KEPPFGEB_01765 7.8e-155 gltC K Transcriptional regulator
KEPPFGEB_01766 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KEPPFGEB_01767 1e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KEPPFGEB_01768 9.4e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KEPPFGEB_01769 4.7e-157 gltR1 K Transcriptional regulator
KEPPFGEB_01770 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KEPPFGEB_01771 3e-34 yoeD G Helix-turn-helix domain
KEPPFGEB_01772 2.2e-96 L Integrase
KEPPFGEB_01774 1.2e-97 yoeB S IseA DL-endopeptidase inhibitor
KEPPFGEB_01775 2.3e-246 yoeA V MATE efflux family protein
KEPPFGEB_01776 1.3e-184 yoxA 5.1.3.3 G Aldose 1-epimerase
KEPPFGEB_01777 2.9e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KEPPFGEB_01778 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEPPFGEB_01779 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEPPFGEB_01780 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEPPFGEB_01781 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEPPFGEB_01782 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
KEPPFGEB_01783 3.1e-63 yngL S Protein of unknown function (DUF1360)
KEPPFGEB_01784 2.5e-302 yngK T Glycosyl hydrolase-like 10
KEPPFGEB_01785 3.7e-24 S Family of unknown function (DUF5367)
KEPPFGEB_01786 3.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
KEPPFGEB_01787 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KEPPFGEB_01788 3.1e-248 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
KEPPFGEB_01789 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
KEPPFGEB_01790 3.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
KEPPFGEB_01791 9.2e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KEPPFGEB_01792 1.3e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KEPPFGEB_01793 9.5e-233 nrnB S phosphohydrolase (DHH superfamily)
KEPPFGEB_01794 5.5e-104 yngC S membrane-associated protein
KEPPFGEB_01795 1.2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KEPPFGEB_01796 2e-79 yngA S membrane
KEPPFGEB_01797 3.6e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KEPPFGEB_01798 4e-214 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
KEPPFGEB_01800 2.6e-296 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
KEPPFGEB_01801 1.8e-251 agcS E Sodium alanine symporter
KEPPFGEB_01802 8.6e-57 ynfC
KEPPFGEB_01803 2.3e-12
KEPPFGEB_01804 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KEPPFGEB_01805 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KEPPFGEB_01806 6.6e-69 yccU S CoA-binding protein
KEPPFGEB_01807 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KEPPFGEB_01808 4.1e-49 yneR S Belongs to the HesB IscA family
KEPPFGEB_01809 2.2e-53 yneQ
KEPPFGEB_01810 1.2e-73 yneP S Thioesterase-like superfamily
KEPPFGEB_01811 3.9e-35 tlp S Belongs to the Tlp family
KEPPFGEB_01812 3.1e-08 sspN S Small acid-soluble spore protein N family
KEPPFGEB_01814 1e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KEPPFGEB_01815 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KEPPFGEB_01816 2.5e-14 sspO S Belongs to the SspO family
KEPPFGEB_01817 3.9e-19 sspP S Belongs to the SspP family
KEPPFGEB_01818 1.7e-63 hspX O Spore coat protein
KEPPFGEB_01819 4.2e-74 yneK S Protein of unknown function (DUF2621)
KEPPFGEB_01820 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KEPPFGEB_01821 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KEPPFGEB_01822 7.1e-127 ccdA O cytochrome c biogenesis protein
KEPPFGEB_01823 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
KEPPFGEB_01824 1.8e-28 yneF S UPF0154 protein
KEPPFGEB_01825 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
KEPPFGEB_01826 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KEPPFGEB_01827 1.3e-32 ynzC S UPF0291 protein
KEPPFGEB_01828 9.2e-113 yneB L resolvase
KEPPFGEB_01829 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KEPPFGEB_01830 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KEPPFGEB_01831 1.1e-33 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KEPPFGEB_01832 5.8e-74 yndM S Protein of unknown function (DUF2512)
KEPPFGEB_01833 1.3e-134 yndL S Replication protein
KEPPFGEB_01835 3.8e-293 yndJ S YndJ-like protein
KEPPFGEB_01836 7.1e-115 yndH S Domain of unknown function (DUF4166)
KEPPFGEB_01837 5.2e-150 yndG S DoxX-like family
KEPPFGEB_01838 3e-218 gerLC S Spore germination protein
KEPPFGEB_01839 6.1e-194 gerAB U Spore germination
KEPPFGEB_01840 3.7e-285 gerAA EG Spore germination protein
KEPPFGEB_01843 2.6e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
KEPPFGEB_01844 1.8e-71
KEPPFGEB_01845 1e-24 tatA U protein secretion
KEPPFGEB_01848 2.3e-131 S Domain of unknown function, YrpD
KEPPFGEB_01849 1.9e-163 S Thymidylate synthase
KEPPFGEB_01852 4.1e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KEPPFGEB_01853 1e-81 yncE S Protein of unknown function (DUF2691)
KEPPFGEB_01854 2.5e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KEPPFGEB_01855 2.1e-255 iolT EGP Major facilitator Superfamily
KEPPFGEB_01856 1.7e-111 yokF 3.1.31.1 L RNA catabolic process
KEPPFGEB_01857 3.3e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
KEPPFGEB_01858 2e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KEPPFGEB_01859 4.3e-214 xylR GK ROK family
KEPPFGEB_01860 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
KEPPFGEB_01861 2.3e-254 xynT G MFS/sugar transport protein
KEPPFGEB_01864 8.9e-74 S CAAX protease self-immunity
KEPPFGEB_01866 1.3e-96 ynaD J Acetyltransferase (GNAT) domain
KEPPFGEB_01867 1.1e-141 ynaC
KEPPFGEB_01868 1.7e-88 G SMI1-KNR4 cell-wall
KEPPFGEB_01869 2.1e-36
KEPPFGEB_01870 4.5e-125
KEPPFGEB_01871 1.3e-31
KEPPFGEB_01872 1.4e-09
KEPPFGEB_01873 7e-261 glnA 6.3.1.2 E glutamine synthetase
KEPPFGEB_01874 1.1e-68 glnR K transcriptional
KEPPFGEB_01875 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KEPPFGEB_01876 2.3e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KEPPFGEB_01877 6.6e-176 spoVK O stage V sporulation protein K
KEPPFGEB_01878 2.2e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KEPPFGEB_01879 1.3e-108 ymaB
KEPPFGEB_01880 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KEPPFGEB_01881 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KEPPFGEB_01882 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
KEPPFGEB_01883 4.5e-22 ymzA
KEPPFGEB_01884 8.2e-23
KEPPFGEB_01885 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KEPPFGEB_01886 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KEPPFGEB_01887 2.1e-46 ymaF S YmaF family
KEPPFGEB_01889 1.2e-49 ebrA P Small Multidrug Resistance protein
KEPPFGEB_01890 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
KEPPFGEB_01891 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
KEPPFGEB_01892 2.1e-126 ymaC S Replication protein
KEPPFGEB_01893 1.9e-07 K Transcriptional regulator
KEPPFGEB_01894 1.3e-251 aprX O Belongs to the peptidase S8 family
KEPPFGEB_01895 2.1e-162 ymaE S Metallo-beta-lactamase superfamily
KEPPFGEB_01896 4.4e-61 ymzB
KEPPFGEB_01897 6.3e-232 cypA C Cytochrome P450
KEPPFGEB_01898 0.0 pks13 HQ Beta-ketoacyl synthase
KEPPFGEB_01899 0.0 dhbF IQ polyketide synthase
KEPPFGEB_01900 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
KEPPFGEB_01901 0.0 pfaA Q Polyketide synthase of type I
KEPPFGEB_01902 0.0 rhiB IQ polyketide synthase
KEPPFGEB_01903 4e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
KEPPFGEB_01904 4.2e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
KEPPFGEB_01905 1.5e-244 pksG 2.3.3.10 I synthase
KEPPFGEB_01906 5.6e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KEPPFGEB_01907 1.4e-37 acpK IQ Phosphopantetheine attachment site
KEPPFGEB_01908 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KEPPFGEB_01909 4e-181 pksD Q Acyl transferase domain
KEPPFGEB_01911 6.4e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KEPPFGEB_01912 3.7e-125 pksB 3.1.2.6 S Polyketide biosynthesis
KEPPFGEB_01913 2.4e-107 pksA K Transcriptional regulator
KEPPFGEB_01914 3e-96 ymcC S Membrane
KEPPFGEB_01916 3.1e-70 S Regulatory protein YrvL
KEPPFGEB_01917 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KEPPFGEB_01918 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KEPPFGEB_01919 2.2e-88 cotE S Spore coat protein
KEPPFGEB_01920 5.9e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KEPPFGEB_01921 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KEPPFGEB_01922 1.4e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KEPPFGEB_01923 3.9e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KEPPFGEB_01924 1.2e-36 spoVS S Stage V sporulation protein S
KEPPFGEB_01925 1.9e-152 ymdB S protein conserved in bacteria
KEPPFGEB_01926 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
KEPPFGEB_01927 9.1e-212 pbpX V Beta-lactamase
KEPPFGEB_01928 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KEPPFGEB_01929 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
KEPPFGEB_01930 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KEPPFGEB_01931 1.9e-124 ymfM S protein conserved in bacteria
KEPPFGEB_01932 2.7e-143 ymfK S Protein of unknown function (DUF3388)
KEPPFGEB_01933 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
KEPPFGEB_01934 1.9e-127 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KEPPFGEB_01935 2.1e-241 ymfH S zinc protease
KEPPFGEB_01936 7.8e-233 ymfF S Peptidase M16
KEPPFGEB_01937 3.8e-205 ymfD EGP Major facilitator Superfamily
KEPPFGEB_01938 1.4e-133 ymfC K Transcriptional regulator
KEPPFGEB_01939 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KEPPFGEB_01940 4.4e-32 S YlzJ-like protein
KEPPFGEB_01941 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KEPPFGEB_01942 2.1e-307 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KEPPFGEB_01943 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KEPPFGEB_01944 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KEPPFGEB_01945 4.1e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KEPPFGEB_01946 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KEPPFGEB_01947 6.6e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KEPPFGEB_01948 2.6e-42 ymxH S YlmC YmxH family
KEPPFGEB_01949 4.4e-233 pepR S Belongs to the peptidase M16 family
KEPPFGEB_01950 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KEPPFGEB_01951 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KEPPFGEB_01952 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KEPPFGEB_01953 4.3e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KEPPFGEB_01954 3.6e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KEPPFGEB_01955 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KEPPFGEB_01956 3.9e-44 ylxP S protein conserved in bacteria
KEPPFGEB_01957 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KEPPFGEB_01958 3.1e-47 ylxQ J ribosomal protein
KEPPFGEB_01959 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
KEPPFGEB_01960 1.1e-203 nusA K Participates in both transcription termination and antitermination
KEPPFGEB_01961 7.4e-80 rimP S Required for maturation of 30S ribosomal subunits
KEPPFGEB_01962 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KEPPFGEB_01963 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KEPPFGEB_01964 7.7e-233 rasP M zinc metalloprotease
KEPPFGEB_01965 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KEPPFGEB_01966 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
KEPPFGEB_01967 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KEPPFGEB_01968 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KEPPFGEB_01969 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KEPPFGEB_01970 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KEPPFGEB_01971 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
KEPPFGEB_01972 1.4e-76 ylxL
KEPPFGEB_01973 7.4e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEPPFGEB_01974 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KEPPFGEB_01975 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KEPPFGEB_01976 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
KEPPFGEB_01977 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KEPPFGEB_01978 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KEPPFGEB_01979 9.8e-158 flhG D Belongs to the ParA family
KEPPFGEB_01980 6.8e-201 flhF N Flagellar biosynthesis regulator FlhF
KEPPFGEB_01981 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KEPPFGEB_01982 4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KEPPFGEB_01983 1.1e-131 fliR N Flagellar biosynthetic protein FliR
KEPPFGEB_01984 2.2e-36 fliQ N Role in flagellar biosynthesis
KEPPFGEB_01985 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
KEPPFGEB_01986 6e-96 fliZ N Flagellar biosynthesis protein, FliO
KEPPFGEB_01987 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
KEPPFGEB_01988 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KEPPFGEB_01989 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KEPPFGEB_01990 1.8e-48 fliL N Controls the rotational direction of flagella during chemotaxis
KEPPFGEB_01991 8.2e-140 flgG N Flagellar basal body rod
KEPPFGEB_01992 1.7e-72 flgD N Flagellar basal body rod modification protein
KEPPFGEB_01993 4.4e-216 fliK N Flagellar hook-length control protein
KEPPFGEB_01994 5.5e-35 ylxF S MgtE intracellular N domain
KEPPFGEB_01995 1.5e-69 fliJ N Flagellar biosynthesis chaperone
KEPPFGEB_01996 2.1e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KEPPFGEB_01997 2.8e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KEPPFGEB_01998 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KEPPFGEB_01999 2e-254 fliF N The M ring may be actively involved in energy transduction
KEPPFGEB_02000 1.9e-31 fliE N Flagellar hook-basal body
KEPPFGEB_02001 3.4e-74 flgC N Belongs to the flagella basal body rod proteins family
KEPPFGEB_02002 8.8e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KEPPFGEB_02003 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KEPPFGEB_02004 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KEPPFGEB_02005 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KEPPFGEB_02006 2.5e-169 xerC L tyrosine recombinase XerC
KEPPFGEB_02007 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KEPPFGEB_02008 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KEPPFGEB_02009 2.3e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KEPPFGEB_02010 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KEPPFGEB_02011 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KEPPFGEB_02012 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KEPPFGEB_02013 1.8e-288 ylqG
KEPPFGEB_02014 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KEPPFGEB_02015 7.9e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KEPPFGEB_02016 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KEPPFGEB_02017 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KEPPFGEB_02018 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KEPPFGEB_02019 1.4e-60 ylqD S YlqD protein
KEPPFGEB_02020 4.5e-36 ylqC S Belongs to the UPF0109 family
KEPPFGEB_02021 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KEPPFGEB_02022 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KEPPFGEB_02023 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KEPPFGEB_02024 6.4e-87
KEPPFGEB_02025 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KEPPFGEB_02026 0.0 smc D Required for chromosome condensation and partitioning
KEPPFGEB_02027 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KEPPFGEB_02028 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KEPPFGEB_02029 2.3e-128 IQ reductase
KEPPFGEB_02030 2.2e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KEPPFGEB_02031 2.1e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KEPPFGEB_02032 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KEPPFGEB_02033 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KEPPFGEB_02034 1.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
KEPPFGEB_02035 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
KEPPFGEB_02036 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
KEPPFGEB_02037 5.5e-59 asp S protein conserved in bacteria
KEPPFGEB_02038 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KEPPFGEB_02039 4.5e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
KEPPFGEB_02040 9.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KEPPFGEB_02041 7.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KEPPFGEB_02042 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KEPPFGEB_02043 1.6e-140 stp 3.1.3.16 T phosphatase
KEPPFGEB_02044 9e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KEPPFGEB_02045 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KEPPFGEB_02046 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KEPPFGEB_02047 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KEPPFGEB_02048 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KEPPFGEB_02049 4.1e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KEPPFGEB_02050 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KEPPFGEB_02051 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KEPPFGEB_02052 1.5e-40 ylzA S Belongs to the UPF0296 family
KEPPFGEB_02053 2.4e-156 yloC S stress-induced protein
KEPPFGEB_02054 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KEPPFGEB_02055 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KEPPFGEB_02056 2.4e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KEPPFGEB_02057 1.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KEPPFGEB_02058 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KEPPFGEB_02059 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
KEPPFGEB_02060 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KEPPFGEB_02061 1.1e-179 cysP P phosphate transporter
KEPPFGEB_02062 1.9e-140 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KEPPFGEB_02064 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KEPPFGEB_02065 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KEPPFGEB_02066 1e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KEPPFGEB_02067 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KEPPFGEB_02068 0.0 carB 6.3.5.5 F Belongs to the CarB family
KEPPFGEB_02069 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KEPPFGEB_02070 8.3e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KEPPFGEB_02071 1.7e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KEPPFGEB_02072 8.4e-230 pyrP F Xanthine uracil
KEPPFGEB_02073 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KEPPFGEB_02074 4.2e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KEPPFGEB_02075 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KEPPFGEB_02076 8.5e-63 dksA T COG1734 DnaK suppressor protein
KEPPFGEB_02077 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KEPPFGEB_02078 2.6e-67 divIVA D Cell division initiation protein
KEPPFGEB_02079 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KEPPFGEB_02080 1.3e-39 yggT S membrane
KEPPFGEB_02081 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KEPPFGEB_02082 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KEPPFGEB_02083 7e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KEPPFGEB_02084 2.4e-37 ylmC S sporulation protein
KEPPFGEB_02085 4e-253 argE 3.5.1.16 E Acetylornithine deacetylase
KEPPFGEB_02086 6.9e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KEPPFGEB_02087 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEPPFGEB_02088 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEPPFGEB_02089 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KEPPFGEB_02090 0.0 bpr O COG1404 Subtilisin-like serine proteases
KEPPFGEB_02091 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KEPPFGEB_02092 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KEPPFGEB_02093 6.2e-58 sbp S small basic protein
KEPPFGEB_02094 1.3e-102 ylxX S protein conserved in bacteria
KEPPFGEB_02095 2.4e-103 ylxW S protein conserved in bacteria
KEPPFGEB_02096 7.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KEPPFGEB_02097 5.3e-167 murB 1.3.1.98 M cell wall formation
KEPPFGEB_02098 2.5e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KEPPFGEB_02099 1.7e-185 spoVE D Belongs to the SEDS family
KEPPFGEB_02100 1.7e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KEPPFGEB_02101 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KEPPFGEB_02102 2e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KEPPFGEB_02103 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KEPPFGEB_02104 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KEPPFGEB_02105 3.7e-44 ftsL D Essential cell division protein
KEPPFGEB_02106 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KEPPFGEB_02107 2.9e-78 mraZ K Belongs to the MraZ family
KEPPFGEB_02108 1.3e-306 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KEPPFGEB_02109 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KEPPFGEB_02110 1.5e-88 ylbP K n-acetyltransferase
KEPPFGEB_02111 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KEPPFGEB_02112 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KEPPFGEB_02113 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
KEPPFGEB_02115 4.9e-232 ylbM S Belongs to the UPF0348 family
KEPPFGEB_02116 6.8e-187 ylbL T Belongs to the peptidase S16 family
KEPPFGEB_02117 1.3e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
KEPPFGEB_02118 9.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
KEPPFGEB_02119 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KEPPFGEB_02120 6e-97 rsmD 2.1.1.171 L Methyltransferase
KEPPFGEB_02121 7.5e-39 ylbG S UPF0298 protein
KEPPFGEB_02122 1.8e-75 ylbF S Belongs to the UPF0342 family
KEPPFGEB_02123 6.7e-37 ylbE S YlbE-like protein
KEPPFGEB_02124 2.6e-62 ylbD S Putative coat protein
KEPPFGEB_02125 2.8e-199 ylbC S protein with SCP PR1 domains
KEPPFGEB_02126 2.6e-74 ylbB T COG0517 FOG CBS domain
KEPPFGEB_02127 7e-62 ylbA S YugN-like family
KEPPFGEB_02128 1.5e-166 ctaG S cytochrome c oxidase
KEPPFGEB_02129 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KEPPFGEB_02130 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KEPPFGEB_02131 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KEPPFGEB_02132 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KEPPFGEB_02133 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KEPPFGEB_02134 8.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KEPPFGEB_02135 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KEPPFGEB_02136 2.5e-212 ftsW D Belongs to the SEDS family
KEPPFGEB_02137 8.7e-44 ylaN S Belongs to the UPF0358 family
KEPPFGEB_02138 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
KEPPFGEB_02139 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KEPPFGEB_02140 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KEPPFGEB_02141 1.2e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KEPPFGEB_02142 5.6e-32 ylaI S protein conserved in bacteria
KEPPFGEB_02143 4.2e-47 ylaH S YlaH-like protein
KEPPFGEB_02144 0.0 typA T GTP-binding protein TypA
KEPPFGEB_02145 8.2e-22 S Family of unknown function (DUF5325)
KEPPFGEB_02146 2.6e-37 ylaE
KEPPFGEB_02147 1.2e-11 sigC S Putative zinc-finger
KEPPFGEB_02148 3.3e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
KEPPFGEB_02149 2.7e-42 ylaB
KEPPFGEB_02150 0.0 ylaA
KEPPFGEB_02151 3.7e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
KEPPFGEB_02152 3.5e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KEPPFGEB_02153 1.7e-76 ykzC S Acetyltransferase (GNAT) family
KEPPFGEB_02154 3.7e-148 suhB 3.1.3.25 G Inositol monophosphatase
KEPPFGEB_02155 7.1e-26 ykzI
KEPPFGEB_02156 4.6e-117 yktB S Belongs to the UPF0637 family
KEPPFGEB_02157 1.6e-42 yktA S Belongs to the UPF0223 family
KEPPFGEB_02158 1.3e-276 speA 4.1.1.19 E Arginine
KEPPFGEB_02159 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
KEPPFGEB_02160 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KEPPFGEB_02161 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KEPPFGEB_02162 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KEPPFGEB_02163 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KEPPFGEB_02164 7.4e-107 recN L Putative cell-wall binding lipoprotein
KEPPFGEB_02166 3.4e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KEPPFGEB_02167 5.5e-147 ykrA S hydrolases of the HAD superfamily
KEPPFGEB_02168 8.2e-31 ykzG S Belongs to the UPF0356 family
KEPPFGEB_02169 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KEPPFGEB_02170 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KEPPFGEB_02171 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
KEPPFGEB_02172 6.5e-156 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
KEPPFGEB_02173 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KEPPFGEB_02174 1.5e-43 abrB K of stationary sporulation gene expression
KEPPFGEB_02175 7.7e-183 mreB D Rod-share determining protein MreBH
KEPPFGEB_02176 1.1e-12 S Uncharacterized protein YkpC
KEPPFGEB_02177 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KEPPFGEB_02178 3.1e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KEPPFGEB_02179 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KEPPFGEB_02180 8.1e-39 ykoA
KEPPFGEB_02181 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KEPPFGEB_02182 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KEPPFGEB_02183 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KEPPFGEB_02184 2.6e-135 fruR K Transcriptional regulator
KEPPFGEB_02185 8.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
KEPPFGEB_02186 2.5e-124 macB V ABC transporter, ATP-binding protein
KEPPFGEB_02187 2.5e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KEPPFGEB_02188 4.7e-115 yknW S Yip1 domain
KEPPFGEB_02189 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
KEPPFGEB_02190 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
KEPPFGEB_02191 1.1e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KEPPFGEB_02192 8.6e-81 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KEPPFGEB_02193 1.1e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KEPPFGEB_02194 1.7e-243 moeA 2.10.1.1 H molybdopterin
KEPPFGEB_02195 2.6e-191 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KEPPFGEB_02196 9.6e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KEPPFGEB_02197 7.9e-145 yknT
KEPPFGEB_02198 1.5e-93 rok K Repressor of ComK
KEPPFGEB_02199 1.4e-80 ykuV CO thiol-disulfide
KEPPFGEB_02200 3.9e-101 ykuU O Alkyl hydroperoxide reductase
KEPPFGEB_02201 8.8e-142 ykuT M Mechanosensitive ion channel
KEPPFGEB_02202 9e-37 ykuS S Belongs to the UPF0180 family
KEPPFGEB_02203 2.7e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KEPPFGEB_02204 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KEPPFGEB_02205 8.7e-78 fld C Flavodoxin
KEPPFGEB_02206 4e-175 ykuO
KEPPFGEB_02207 5.9e-85 fld C Flavodoxin domain
KEPPFGEB_02208 3.5e-168 ccpC K Transcriptional regulator
KEPPFGEB_02209 1.6e-76 ykuL S CBS domain
KEPPFGEB_02210 3.9e-27 ykzF S Antirepressor AbbA
KEPPFGEB_02211 4.4e-94 ykuK S Ribonuclease H-like
KEPPFGEB_02212 3.9e-37 ykuJ S protein conserved in bacteria
KEPPFGEB_02213 1.1e-233 ykuI T Diguanylate phosphodiesterase
KEPPFGEB_02214 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEPPFGEB_02215 2.1e-165 ykuE S Metallophosphoesterase
KEPPFGEB_02216 1.8e-87 ykuD S protein conserved in bacteria
KEPPFGEB_02217 2.8e-238 ykuC EGP Major facilitator Superfamily
KEPPFGEB_02218 1.7e-84 ykyB S YkyB-like protein
KEPPFGEB_02219 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
KEPPFGEB_02220 1.3e-15
KEPPFGEB_02221 2.8e-221 patA 2.6.1.1 E Aminotransferase
KEPPFGEB_02222 0.0 pilS 2.7.13.3 T Histidine kinase
KEPPFGEB_02223 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
KEPPFGEB_02224 7e-120 ykwD J protein with SCP PR1 domains
KEPPFGEB_02225 3.5e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
KEPPFGEB_02226 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KEPPFGEB_02227 4.1e-257 mcpC NT chemotaxis protein
KEPPFGEB_02228 3.2e-47 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEPPFGEB_02229 1.9e-44 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEPPFGEB_02230 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
KEPPFGEB_02231 7.2e-39 splA S Transcriptional regulator
KEPPFGEB_02232 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KEPPFGEB_02233 2.1e-39 ptsH G phosphocarrier protein HPr
KEPPFGEB_02234 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEPPFGEB_02235 7.6e-128 glcT K antiterminator
KEPPFGEB_02237 1.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
KEPPFGEB_02239 2.5e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KEPPFGEB_02240 2.3e-09
KEPPFGEB_02241 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KEPPFGEB_02242 1.2e-88 stoA CO thiol-disulfide
KEPPFGEB_02243 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEPPFGEB_02244 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
KEPPFGEB_02245 2.7e-28
KEPPFGEB_02246 6e-25 ykvS S protein conserved in bacteria
KEPPFGEB_02247 5.6e-46 ykvR S Protein of unknown function (DUF3219)
KEPPFGEB_02248 2e-161 G Glycosyl hydrolases family 18
KEPPFGEB_02249 3.5e-35 3.5.1.104 M LysM domain
KEPPFGEB_02250 4.9e-215 ykvP 3.5.1.28 M Glycosyl transferases group 1
KEPPFGEB_02251 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
KEPPFGEB_02252 2e-61 ykvN K Transcriptional regulator
KEPPFGEB_02253 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KEPPFGEB_02254 8.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KEPPFGEB_02255 6.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
KEPPFGEB_02256 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KEPPFGEB_02257 6.2e-180 ykvI S membrane
KEPPFGEB_02258 0.0 clpE O Belongs to the ClpA ClpB family
KEPPFGEB_02259 2.7e-138 motA N flagellar motor
KEPPFGEB_02260 2.5e-125 motB N Flagellar motor protein
KEPPFGEB_02261 1.3e-75 ykvE K transcriptional
KEPPFGEB_02262 1.1e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
KEPPFGEB_02263 1.4e-64 eag
KEPPFGEB_02264 6.4e-09 S Spo0E like sporulation regulatory protein
KEPPFGEB_02265 2.2e-51 XK27_09985 S Protein of unknown function (DUF1232)
KEPPFGEB_02266 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KEPPFGEB_02267 2.3e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KEPPFGEB_02268 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KEPPFGEB_02269 1.2e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KEPPFGEB_02270 9.8e-230 mtnE 2.6.1.83 E Aminotransferase
KEPPFGEB_02271 1e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KEPPFGEB_02272 1.2e-227 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KEPPFGEB_02273 6.3e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KEPPFGEB_02275 5.9e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KEPPFGEB_02276 0.0 kinE 2.7.13.3 T Histidine kinase
KEPPFGEB_02277 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KEPPFGEB_02278 4.1e-18 ykzE
KEPPFGEB_02279 1.2e-10 ydfR S Protein of unknown function (DUF421)
KEPPFGEB_02280 6.3e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
KEPPFGEB_02281 3.5e-155 htpX O Belongs to the peptidase M48B family
KEPPFGEB_02282 2.3e-122 ykrK S Domain of unknown function (DUF1836)
KEPPFGEB_02283 1.9e-26 sspD S small acid-soluble spore protein
KEPPFGEB_02284 7.4e-110 rsgI S Anti-sigma factor N-terminus
KEPPFGEB_02285 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEPPFGEB_02286 3e-176 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KEPPFGEB_02287 3.5e-109 ykoX S membrane-associated protein
KEPPFGEB_02288 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
KEPPFGEB_02289 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KEPPFGEB_02290 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
KEPPFGEB_02291 4.8e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KEPPFGEB_02292 0.0 ykoS
KEPPFGEB_02293 2.7e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
KEPPFGEB_02294 2.7e-97 ykoP G polysaccharide deacetylase
KEPPFGEB_02295 4.7e-218 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KEPPFGEB_02296 1.3e-81 mhqR K transcriptional
KEPPFGEB_02297 6.9e-26 ykoL
KEPPFGEB_02298 5.9e-18
KEPPFGEB_02299 1.4e-53 tnrA K transcriptional
KEPPFGEB_02300 2.2e-222 mgtE P Acts as a magnesium transporter
KEPPFGEB_02303 1.1e-84 ykoJ S Peptidase propeptide and YPEB domain
KEPPFGEB_02304 3.3e-113 ykoI S Peptidase propeptide and YPEB domain
KEPPFGEB_02305 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
KEPPFGEB_02306 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEPPFGEB_02307 6.7e-110 ykoF S YKOF-related Family
KEPPFGEB_02308 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
KEPPFGEB_02309 4.6e-311 P ABC transporter, ATP-binding protein
KEPPFGEB_02310 2.9e-134 ykoC P Cobalt transport protein
KEPPFGEB_02311 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KEPPFGEB_02312 1.7e-176 isp O Belongs to the peptidase S8 family
KEPPFGEB_02313 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KEPPFGEB_02314 8.1e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
KEPPFGEB_02315 8.4e-72 ohrB O Organic hydroperoxide resistance protein
KEPPFGEB_02316 2.8e-73 ohrR K COG1846 Transcriptional regulators
KEPPFGEB_02317 1.3e-70 ohrA O Organic hydroperoxide resistance protein
KEPPFGEB_02318 6.9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KEPPFGEB_02319 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KEPPFGEB_02320 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KEPPFGEB_02321 7e-50 ykkD P Multidrug resistance protein
KEPPFGEB_02322 2.9e-54 ykkC P Multidrug resistance protein
KEPPFGEB_02323 1.1e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KEPPFGEB_02324 3.9e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KEPPFGEB_02325 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KEPPFGEB_02326 3.8e-151 ykgA E Amidinotransferase
KEPPFGEB_02327 2.4e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
KEPPFGEB_02328 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
KEPPFGEB_02329 4.7e-168 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KEPPFGEB_02330 1.8e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KEPPFGEB_02331 2.4e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KEPPFGEB_02333 0.0 dppE E ABC transporter substrate-binding protein
KEPPFGEB_02334 5.6e-186 dppD P Belongs to the ABC transporter superfamily
KEPPFGEB_02335 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEPPFGEB_02336 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEPPFGEB_02337 5.1e-153 dppA E D-aminopeptidase
KEPPFGEB_02338 4.1e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
KEPPFGEB_02339 2.2e-209 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KEPPFGEB_02341 4.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KEPPFGEB_02342 3.6e-310 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KEPPFGEB_02343 5.1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
KEPPFGEB_02344 9.8e-239 steT E amino acid
KEPPFGEB_02345 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
KEPPFGEB_02346 5.8e-175 pit P phosphate transporter
KEPPFGEB_02347 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KEPPFGEB_02348 6.7e-23 spoIISB S Stage II sporulation protein SB
KEPPFGEB_02350 9.5e-161 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KEPPFGEB_02351 9.3e-40 xhlB S SPP1 phage holin
KEPPFGEB_02352 6.2e-39 xhlA S Haemolysin XhlA
KEPPFGEB_02353 3.7e-151 xepA
KEPPFGEB_02354 5.5e-22 xkdX
KEPPFGEB_02355 1.3e-43 S XkdW protein
KEPPFGEB_02356 0.0
KEPPFGEB_02357 6.7e-41
KEPPFGEB_02358 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KEPPFGEB_02359 5.1e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KEPPFGEB_02360 3.1e-69 xkdS S Protein of unknown function (DUF2634)
KEPPFGEB_02361 2.3e-38 xkdR S Protein of unknown function (DUF2577)
KEPPFGEB_02362 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
KEPPFGEB_02363 2.7e-118 xkdP S Lysin motif
KEPPFGEB_02364 5.2e-227 xkdO L Transglycosylase SLT domain
KEPPFGEB_02365 6.7e-167 ygxA S Nucleotidyltransferase-like
KEPPFGEB_02366 9.5e-56 ygzB S UPF0295 protein
KEPPFGEB_02367 4e-80 perR P Belongs to the Fur family
KEPPFGEB_02368 8.2e-87 bcp 1.11.1.15 O Peroxiredoxin
KEPPFGEB_02369 7.6e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KEPPFGEB_02370 3.3e-179 ygaE S Membrane
KEPPFGEB_02371 7e-301 ygaD V ABC transporter
KEPPFGEB_02372 1.3e-104 ygaC J Belongs to the UPF0374 family
KEPPFGEB_02373 1.5e-37 ygaB S YgaB-like protein
KEPPFGEB_02374 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
KEPPFGEB_02375 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEPPFGEB_02376 6.9e-36 yfhS
KEPPFGEB_02377 7.3e-210 mutY L A G-specific
KEPPFGEB_02378 1.2e-185 yfhP S membrane-bound metal-dependent
KEPPFGEB_02379 0.0 yfhO S Bacterial membrane protein YfhO
KEPPFGEB_02380 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KEPPFGEB_02381 1.3e-170 yfhM S Alpha beta hydrolase
KEPPFGEB_02382 1e-47 yfhL S SdpI/YhfL protein family
KEPPFGEB_02383 7.8e-91 batE T Bacterial SH3 domain homologues
KEPPFGEB_02384 1.3e-44 yfhJ S WVELL protein
KEPPFGEB_02385 6.2e-20 sspK S reproduction
KEPPFGEB_02386 2.5e-209 yfhI EGP Major facilitator Superfamily
KEPPFGEB_02388 9.7e-52 yfhH S Protein of unknown function (DUF1811)
KEPPFGEB_02389 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
KEPPFGEB_02390 6e-171 yfhF S nucleoside-diphosphate sugar epimerase
KEPPFGEB_02392 2.1e-25 yfhD S YfhD-like protein
KEPPFGEB_02393 4.4e-106 yfhC C nitroreductase
KEPPFGEB_02394 1.1e-166 yfhB 5.3.3.17 S PhzF family
KEPPFGEB_02395 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEPPFGEB_02396 3.4e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEPPFGEB_02397 5.7e-175 yfiY P ABC transporter substrate-binding protein
KEPPFGEB_02398 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KEPPFGEB_02399 4.9e-79 yfiV K transcriptional
KEPPFGEB_02400 8.5e-282 yfiU EGP Major facilitator Superfamily
KEPPFGEB_02401 3.6e-99 yfiT S Belongs to the metal hydrolase YfiT family
KEPPFGEB_02402 3.8e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KEPPFGEB_02403 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KEPPFGEB_02404 8.3e-99 padR K transcriptional
KEPPFGEB_02405 2.9e-202 V COG0842 ABC-type multidrug transport system, permease component
KEPPFGEB_02406 1.2e-203 V ABC-2 family transporter protein
KEPPFGEB_02407 5.4e-167 V ABC transporter, ATP-binding protein
KEPPFGEB_02408 2.8e-109 KT LuxR family transcriptional regulator
KEPPFGEB_02409 6.9e-188 yxjM T Histidine kinase
KEPPFGEB_02410 6.3e-162 yfiE 1.13.11.2 S glyoxalase
KEPPFGEB_02411 9.8e-65 mhqP S DoxX
KEPPFGEB_02412 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KEPPFGEB_02413 8.4e-307 yfiB3 V ABC transporter
KEPPFGEB_02414 0.0 yobO M COG5434 Endopolygalacturonase
KEPPFGEB_02415 1.2e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEPPFGEB_02416 4.6e-140 glvR K Helix-turn-helix domain, rpiR family
KEPPFGEB_02417 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KEPPFGEB_02418 2.6e-44 yfjA S Belongs to the WXG100 family
KEPPFGEB_02419 1.4e-170 yfjB
KEPPFGEB_02420 1.2e-124 yfjC
KEPPFGEB_02421 4e-85 S Family of unknown function (DUF5381)
KEPPFGEB_02422 5.2e-56 yfjF S UPF0060 membrane protein
KEPPFGEB_02423 1.3e-24 sspH S Belongs to the SspH family
KEPPFGEB_02424 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KEPPFGEB_02425 1.2e-255 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KEPPFGEB_02426 3.2e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KEPPFGEB_02427 1.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KEPPFGEB_02428 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KEPPFGEB_02429 5.1e-29 yfjL
KEPPFGEB_02430 3.9e-86 yfjM S Psort location Cytoplasmic, score
KEPPFGEB_02431 1.8e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KEPPFGEB_02432 6.3e-42 S YfzA-like protein
KEPPFGEB_02433 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KEPPFGEB_02434 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KEPPFGEB_02435 1.7e-184 corA P Mediates influx of magnesium ions
KEPPFGEB_02436 1.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KEPPFGEB_02437 1.7e-153 pdaA G deacetylase
KEPPFGEB_02438 1.1e-26 yfjT
KEPPFGEB_02439 5.4e-222 yfkA S YfkB-like domain
KEPPFGEB_02440 1.3e-148 yfkC M Mechanosensitive ion channel
KEPPFGEB_02441 1.2e-146 yfkD S YfkD-like protein
KEPPFGEB_02442 6.1e-183 cax P COG0387 Ca2 H antiporter
KEPPFGEB_02443 4.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
KEPPFGEB_02444 5e-08
KEPPFGEB_02445 1.3e-143 yihY S Belongs to the UPF0761 family
KEPPFGEB_02446 4.1e-50 yfkI S gas vesicle protein
KEPPFGEB_02447 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KEPPFGEB_02448 1.3e-28 yfkK S Belongs to the UPF0435 family
KEPPFGEB_02449 1.3e-205 ydiM EGP Major facilitator Superfamily
KEPPFGEB_02450 3.6e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
KEPPFGEB_02451 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KEPPFGEB_02452 1.1e-124 yfkO C nitroreductase
KEPPFGEB_02453 1.8e-133 treR K transcriptional
KEPPFGEB_02454 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KEPPFGEB_02455 9.4e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEPPFGEB_02456 1.5e-283 yfkQ EG Spore germination protein
KEPPFGEB_02457 5.1e-207 yfkR S spore germination
KEPPFGEB_02459 1.3e-193 E Spore germination protein
KEPPFGEB_02460 3.1e-251 agcS_1 E Sodium alanine symporter
KEPPFGEB_02461 6e-67 yhdN S Domain of unknown function (DUF1992)
KEPPFGEB_02462 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KEPPFGEB_02463 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KEPPFGEB_02464 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
KEPPFGEB_02465 5.9e-49 yflH S Protein of unknown function (DUF3243)
KEPPFGEB_02466 4.1e-19 yflI
KEPPFGEB_02467 8.9e-18 yflJ S Protein of unknown function (DUF2639)
KEPPFGEB_02468 6.4e-122 yflK S protein conserved in bacteria
KEPPFGEB_02469 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KEPPFGEB_02470 5.6e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KEPPFGEB_02471 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KEPPFGEB_02472 8.5e-227 citM C Citrate transporter
KEPPFGEB_02473 6.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
KEPPFGEB_02474 2.2e-117 citT T response regulator
KEPPFGEB_02475 3.7e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KEPPFGEB_02476 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
KEPPFGEB_02477 1.4e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
KEPPFGEB_02478 7.6e-58 yflT S Heat induced stress protein YflT
KEPPFGEB_02479 2.9e-24 S Protein of unknown function (DUF3212)
KEPPFGEB_02480 3.6e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KEPPFGEB_02481 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEPPFGEB_02482 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEPPFGEB_02483 4.4e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
KEPPFGEB_02484 2.6e-186 yfmJ S N-terminal domain of oxidoreductase
KEPPFGEB_02485 4.7e-76 yfmK 2.3.1.128 K acetyltransferase
KEPPFGEB_02486 2.2e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KEPPFGEB_02487 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KEPPFGEB_02488 6.2e-208 yfmO EGP Major facilitator Superfamily
KEPPFGEB_02489 1.4e-69 yfmP K transcriptional
KEPPFGEB_02490 2.8e-73 yfmQ S Uncharacterised protein from bacillus cereus group
KEPPFGEB_02491 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KEPPFGEB_02492 1.1e-113 yfmS NT chemotaxis protein
KEPPFGEB_02493 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEPPFGEB_02494 6.4e-241 yfnA E amino acid
KEPPFGEB_02495 7.2e-36 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KEPPFGEB_02496 6.4e-81 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KEPPFGEB_02497 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
KEPPFGEB_02498 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
KEPPFGEB_02499 1.2e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
KEPPFGEB_02500 1e-178 yfnF M Nucleotide-diphospho-sugar transferase
KEPPFGEB_02501 3.2e-172 yfnG 4.2.1.45 M dehydratase
KEPPFGEB_02502 7.4e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
KEPPFGEB_02503 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KEPPFGEB_02504 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KEPPFGEB_02505 3.7e-196 yetN S Protein of unknown function (DUF3900)
KEPPFGEB_02506 3.2e-134 M Membrane
KEPPFGEB_02507 6.4e-207 yetM CH FAD binding domain
KEPPFGEB_02508 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
KEPPFGEB_02509 7e-151 yetK EG EamA-like transporter family
KEPPFGEB_02510 2.9e-145 1.1.1.136, 1.1.1.336 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KEPPFGEB_02511 1.2e-41 J B3 4 domain protein
KEPPFGEB_02512 7.8e-33 S inositol 2-dehydrogenase activity
KEPPFGEB_02513 3.7e-96 gal 1.1.1.376, 1.1.1.48 S inositol 2-dehydrogenase activity
KEPPFGEB_02514 7.2e-102 C Belongs to the LDH2 MDH2 oxidoreductase family
KEPPFGEB_02515 4.8e-105 3.5.1.16 E succinyl-diaminopimelate desuccinylase activity
KEPPFGEB_02516 5.9e-75 G Xylose isomerase-like TIM barrel
KEPPFGEB_02517 1.9e-113 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
KEPPFGEB_02518 1.5e-113 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
KEPPFGEB_02519 8e-71 S inositol 2-dehydrogenase activity
KEPPFGEB_02520 6.5e-50 trpF 5.3.1.24 F Belongs to the TrpF family
KEPPFGEB_02521 1.7e-68 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KEPPFGEB_02522 7.7e-150 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KEPPFGEB_02523 2.9e-73 trpC 4.1.1.48 E Belongs to the TrpC family
KEPPFGEB_02524 2.9e-68 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KEPPFGEB_02525 1.3e-124 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEPPFGEB_02526 5.3e-105 yetJ S Belongs to the BI1 family
KEPPFGEB_02527 5.8e-19 yezD S Uncharacterized small protein (DUF2292)
KEPPFGEB_02528 1.9e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KEPPFGEB_02529 2.6e-34
KEPPFGEB_02530 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEPPFGEB_02531 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
KEPPFGEB_02532 5.2e-122 yetF S membrane
KEPPFGEB_02533 2.3e-251 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KEPPFGEB_02534 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
KEPPFGEB_02535 3.2e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KEPPFGEB_02536 1.5e-288 lplA G Bacterial extracellular solute-binding protein
KEPPFGEB_02537 0.0 yetA
KEPPFGEB_02538 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
KEPPFGEB_02539 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
KEPPFGEB_02540 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KEPPFGEB_02541 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KEPPFGEB_02542 3.3e-17 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KEPPFGEB_02543 4.4e-112 yesV S Protein of unknown function, DUF624
KEPPFGEB_02544 5.6e-126 yesU S Domain of unknown function (DUF1961)
KEPPFGEB_02545 1.1e-129 E GDSL-like Lipase/Acylhydrolase
KEPPFGEB_02546 0.0 yesS K Transcriptional regulator
KEPPFGEB_02547 2.7e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
KEPPFGEB_02548 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
KEPPFGEB_02549 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
KEPPFGEB_02550 9.5e-247 yesO G Bacterial extracellular solute-binding protein
KEPPFGEB_02551 1.2e-202 yesN K helix_turn_helix, arabinose operon control protein
KEPPFGEB_02552 0.0 yesM 2.7.13.3 T Histidine kinase
KEPPFGEB_02553 5.4e-102 yesL S Protein of unknown function, DUF624
KEPPFGEB_02555 3.3e-100 yesJ K Acetyltransferase (GNAT) family
KEPPFGEB_02556 5.2e-104 cotJC P Spore Coat
KEPPFGEB_02557 1.5e-45 cotJB S CotJB protein
KEPPFGEB_02558 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
KEPPFGEB_02559 3.5e-149 yesF GM NAD(P)H-binding
KEPPFGEB_02560 6.9e-80 yesE S SnoaL-like domain
KEPPFGEB_02561 9.4e-101 dhaR3 K Transcriptional regulator
KEPPFGEB_02563 2.7e-126 yeeN K transcriptional regulatory protein
KEPPFGEB_02565 8.2e-210 S Tetratricopeptide repeat
KEPPFGEB_02566 7.4e-178 3.4.24.40 CO amine dehydrogenase activity
KEPPFGEB_02567 2.8e-186 yobL S Bacterial EndoU nuclease
KEPPFGEB_02568 5.1e-42 S Immunity protein 22
KEPPFGEB_02570 8.2e-101 S response regulator aspartate phosphatase
KEPPFGEB_02572 1.3e-45
KEPPFGEB_02573 5.8e-126 S Protein of unknown function DUF262
KEPPFGEB_02574 1.1e-139 3.1.21.4 S type ii restriction enzyme
KEPPFGEB_02575 8e-149 2.1.1.37 L C-5 cytosine-specific DNA methylase
KEPPFGEB_02576 2.1e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KEPPFGEB_02577 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KEPPFGEB_02578 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KEPPFGEB_02579 3.1e-145 yerO K Transcriptional regulator
KEPPFGEB_02580 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KEPPFGEB_02581 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KEPPFGEB_02582 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KEPPFGEB_02583 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEPPFGEB_02584 1.6e-123 sapB S MgtC SapB transporter
KEPPFGEB_02585 2.7e-196 yerI S homoserine kinase type II (protein kinase fold)
KEPPFGEB_02586 1.7e-218 camS S COG4851 Protein involved in sex pheromone biosynthesis
KEPPFGEB_02587 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KEPPFGEB_02588 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KEPPFGEB_02589 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KEPPFGEB_02591 2.6e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
KEPPFGEB_02592 4.8e-51 yerC S protein conserved in bacteria
KEPPFGEB_02593 1.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
KEPPFGEB_02594 0.0 yerA 3.5.4.2 F adenine deaminase
KEPPFGEB_02595 2.7e-27 S Protein of unknown function (DUF2892)
KEPPFGEB_02596 5.9e-225 yjeH E Amino acid permease
KEPPFGEB_02597 1.3e-70 K helix_turn_helix ASNC type
KEPPFGEB_02598 1e-232 purD 6.3.4.13 F Belongs to the GARS family
KEPPFGEB_02599 1e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KEPPFGEB_02600 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KEPPFGEB_02601 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KEPPFGEB_02602 3.6e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KEPPFGEB_02603 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KEPPFGEB_02604 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KEPPFGEB_02605 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KEPPFGEB_02606 1.2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KEPPFGEB_02607 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KEPPFGEB_02608 5.9e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KEPPFGEB_02609 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KEPPFGEB_02610 8e-28 yebG S NETI protein
KEPPFGEB_02611 8.9e-93 yebE S UPF0316 protein
KEPPFGEB_02613 3.4e-117 yebC M Membrane
KEPPFGEB_02614 1.7e-211 pbuG S permease
KEPPFGEB_02615 4.4e-256 S Domain of unknown function (DUF4179)
KEPPFGEB_02616 1.2e-83 K Belongs to the sigma-70 factor family. ECF subfamily
KEPPFGEB_02617 1.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KEPPFGEB_02618 0.0 yebA E COG1305 Transglutaminase-like enzymes
KEPPFGEB_02619 2.9e-221 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KEPPFGEB_02620 5.6e-175 yeaC S COG0714 MoxR-like ATPases
KEPPFGEB_02621 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KEPPFGEB_02622 9.7e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
KEPPFGEB_02623 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KEPPFGEB_02624 4.8e-174 yeaA S Protein of unknown function (DUF4003)
KEPPFGEB_02625 1.3e-156 ydjP I Alpha/beta hydrolase family
KEPPFGEB_02626 1.4e-34 ydjO S Cold-inducible protein YdjO
KEPPFGEB_02628 2.1e-151 ydjN U Involved in the tonB-independent uptake of proteins
KEPPFGEB_02629 4.5e-64 ydjM M Lytic transglycolase
KEPPFGEB_02630 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KEPPFGEB_02631 1.7e-257 iolT EGP Major facilitator Superfamily
KEPPFGEB_02632 1.8e-195 S Ion transport 2 domain protein
KEPPFGEB_02633 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
KEPPFGEB_02634 2.1e-132 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
KEPPFGEB_02635 9.8e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KEPPFGEB_02636 2.5e-113 pspA KT Phage shock protein A
KEPPFGEB_02637 5.8e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
KEPPFGEB_02638 8.1e-252 gutA G MFS/sugar transport protein
KEPPFGEB_02639 3.2e-200 gutB 1.1.1.14 E Dehydrogenase
KEPPFGEB_02640 0.0 K NB-ARC domain
KEPPFGEB_02641 1.1e-152 ydjC S Abhydrolase domain containing 18
KEPPFGEB_02642 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KEPPFGEB_02643 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KEPPFGEB_02644 5.1e-128 ydiL S CAAX protease self-immunity
KEPPFGEB_02645 2.9e-27 ydiK S Domain of unknown function (DUF4305)
KEPPFGEB_02646 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KEPPFGEB_02647 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KEPPFGEB_02648 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KEPPFGEB_02649 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KEPPFGEB_02650 0.0 ydiF S ABC transporter
KEPPFGEB_02651 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KEPPFGEB_02652 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KEPPFGEB_02653 2.7e-123 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KEPPFGEB_02654 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KEPPFGEB_02655 6e-177 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KEPPFGEB_02658 9.8e-237 mmr U Major Facilitator Superfamily
KEPPFGEB_02659 3.4e-77 yffB K Transcriptional regulator
KEPPFGEB_02660 2.1e-88 ywgA 2.1.1.72, 3.1.21.3
KEPPFGEB_02661 1.9e-255 ywfO S COG1078 HD superfamily phosphohydrolases
KEPPFGEB_02662 3.1e-36 ywzC S Belongs to the UPF0741 family
KEPPFGEB_02663 5.1e-110 rsfA_1
KEPPFGEB_02664 7.5e-158 ywfM EG EamA-like transporter family
KEPPFGEB_02665 3.3e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KEPPFGEB_02666 1.1e-156 cysL K Transcriptional regulator
KEPPFGEB_02667 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KEPPFGEB_02668 3.3e-146 ywfI C May function as heme-dependent peroxidase
KEPPFGEB_02669 7.5e-138 IQ Enoyl-(Acyl carrier protein) reductase
KEPPFGEB_02670 1.5e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
KEPPFGEB_02671 1.9e-209 bacE EGP Major facilitator Superfamily
KEPPFGEB_02672 3e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KEPPFGEB_02673 5.1e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEPPFGEB_02674 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KEPPFGEB_02675 7.3e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KEPPFGEB_02676 1.3e-205 ywfA EGP Major facilitator Superfamily
KEPPFGEB_02677 2.8e-249 lysP E amino acid
KEPPFGEB_02678 0.0 rocB E arginine degradation protein
KEPPFGEB_02679 4.1e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KEPPFGEB_02680 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KEPPFGEB_02681 1.2e-77
KEPPFGEB_02682 1.3e-86 spsL 5.1.3.13 M Spore Coat
KEPPFGEB_02683 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KEPPFGEB_02684 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KEPPFGEB_02685 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KEPPFGEB_02686 7.9e-188 spsG M Spore Coat
KEPPFGEB_02687 9.7e-132 spsF M Spore Coat
KEPPFGEB_02688 7.1e-214 spsE 2.5.1.56 M acid synthase
KEPPFGEB_02689 2.2e-162 spsD 2.3.1.210 K Spore Coat
KEPPFGEB_02690 2.3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
KEPPFGEB_02691 5.6e-269 spsB M Capsule polysaccharide biosynthesis protein
KEPPFGEB_02692 1e-142 spsA M Spore Coat
KEPPFGEB_02693 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KEPPFGEB_02694 4.3e-59 ywdK S small membrane protein
KEPPFGEB_02695 3.7e-238 ywdJ F Xanthine uracil
KEPPFGEB_02696 1.3e-48 ywdI S Family of unknown function (DUF5327)
KEPPFGEB_02697 6.1e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KEPPFGEB_02698 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KEPPFGEB_02699 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
KEPPFGEB_02701 1.4e-113 ywdD
KEPPFGEB_02702 1.3e-57 pex K Transcriptional regulator PadR-like family
KEPPFGEB_02703 1.7e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KEPPFGEB_02704 2e-28 ywdA
KEPPFGEB_02705 9.8e-293 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
KEPPFGEB_02706 1.9e-253 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEPPFGEB_02707 2.3e-139 focA P Formate/nitrite transporter
KEPPFGEB_02708 7e-150 sacT K transcriptional antiterminator
KEPPFGEB_02710 0.0 vpr O Belongs to the peptidase S8 family
KEPPFGEB_02711 2.5e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEPPFGEB_02712 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KEPPFGEB_02713 2.9e-202 rodA D Belongs to the SEDS family
KEPPFGEB_02714 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
KEPPFGEB_02715 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KEPPFGEB_02716 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KEPPFGEB_02717 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KEPPFGEB_02718 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KEPPFGEB_02719 1e-35 ywzA S membrane
KEPPFGEB_02720 5.6e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KEPPFGEB_02721 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KEPPFGEB_02722 9.5e-60 gtcA S GtrA-like protein
KEPPFGEB_02723 2.5e-121 ywcC K transcriptional regulator
KEPPFGEB_02725 1.7e-48 ywcB S Protein of unknown function, DUF485
KEPPFGEB_02726 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEPPFGEB_02727 1.8e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KEPPFGEB_02728 1.7e-224 ywbN P Dyp-type peroxidase family protein
KEPPFGEB_02729 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
KEPPFGEB_02730 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
KEPPFGEB_02731 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KEPPFGEB_02732 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KEPPFGEB_02733 4.3e-153 ywbI K Transcriptional regulator
KEPPFGEB_02734 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KEPPFGEB_02735 2.3e-111 ywbG M effector of murein hydrolase
KEPPFGEB_02736 1.9e-209 ywbF EGP Major facilitator Superfamily
KEPPFGEB_02737 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
KEPPFGEB_02738 2.4e-220 ywbD 2.1.1.191 J Methyltransferase
KEPPFGEB_02739 9.9e-67 ywbC 4.4.1.5 E glyoxalase
KEPPFGEB_02740 6.1e-120 ywbB S Protein of unknown function (DUF2711)
KEPPFGEB_02741 5.2e-50 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KEPPFGEB_02742 7.7e-172 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KEPPFGEB_02743 9.2e-270 epr 3.4.21.62 O Belongs to the peptidase S8 family
KEPPFGEB_02744 2e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEPPFGEB_02745 9.9e-152 sacY K transcriptional antiterminator
KEPPFGEB_02746 4.5e-168 gspA M General stress
KEPPFGEB_02747 1.3e-123 ywaF S Integral membrane protein
KEPPFGEB_02748 4e-87 ywaE K Transcriptional regulator
KEPPFGEB_02749 8.3e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KEPPFGEB_02750 1.7e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
KEPPFGEB_02751 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
KEPPFGEB_02752 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KEPPFGEB_02753 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEPPFGEB_02754 1.2e-232 dltB M membrane protein involved in D-alanine export
KEPPFGEB_02755 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEPPFGEB_02756 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KEPPFGEB_02757 4.3e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
KEPPFGEB_02758 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KEPPFGEB_02759 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KEPPFGEB_02760 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KEPPFGEB_02761 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KEPPFGEB_02762 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
KEPPFGEB_02763 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
KEPPFGEB_02764 1.1e-19 yxzF
KEPPFGEB_02765 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KEPPFGEB_02766 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KEPPFGEB_02767 1.3e-213 yxlH EGP Major facilitator Superfamily
KEPPFGEB_02768 6.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KEPPFGEB_02769 8.2e-165 yxlF V ABC transporter, ATP-binding protein
KEPPFGEB_02770 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
KEPPFGEB_02771 2.2e-28
KEPPFGEB_02772 1.2e-44 yxlC S Family of unknown function (DUF5345)
KEPPFGEB_02773 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
KEPPFGEB_02774 5e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
KEPPFGEB_02775 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KEPPFGEB_02776 0.0 cydD V ATP-binding protein
KEPPFGEB_02777 1e-309 cydD V ATP-binding
KEPPFGEB_02778 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KEPPFGEB_02779 4.8e-268 cydA 1.10.3.14 C oxidase, subunit
KEPPFGEB_02780 1.5e-229 cimH C COG3493 Na citrate symporter
KEPPFGEB_02781 6.3e-307 3.4.24.84 O Peptidase family M48
KEPPFGEB_02783 1.1e-155 yxkH G Polysaccharide deacetylase
KEPPFGEB_02784 5.9e-205 msmK P Belongs to the ABC transporter superfamily
KEPPFGEB_02785 4.5e-163 lrp QT PucR C-terminal helix-turn-helix domain
KEPPFGEB_02786 1.5e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEPPFGEB_02787 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KEPPFGEB_02788 1.3e-74 yxkC S Domain of unknown function (DUF4352)
KEPPFGEB_02789 3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KEPPFGEB_02790 2e-77 S Protein of unknown function (DUF1453)
KEPPFGEB_02791 1.4e-178 yxjM T Signal transduction histidine kinase
KEPPFGEB_02792 1.2e-112 K helix_turn_helix, Lux Regulon
KEPPFGEB_02793 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KEPPFGEB_02796 4.6e-85 yxjI S LURP-one-related
KEPPFGEB_02797 3.3e-219 yxjG 2.1.1.14 E Methionine synthase
KEPPFGEB_02798 9.7e-219 yxjG 2.1.1.14 E Methionine synthase
KEPPFGEB_02799 1.8e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KEPPFGEB_02800 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KEPPFGEB_02801 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KEPPFGEB_02802 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
KEPPFGEB_02803 1.3e-142 rlmA 2.1.1.187 Q Methyltransferase domain
KEPPFGEB_02804 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KEPPFGEB_02805 3.6e-104 T Domain of unknown function (DUF4163)
KEPPFGEB_02806 3e-47 yxiS
KEPPFGEB_02807 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
KEPPFGEB_02808 6.6e-224 citH C Citrate transporter
KEPPFGEB_02809 1.1e-143 exoK GH16 M licheninase activity
KEPPFGEB_02810 8.3e-151 licT K transcriptional antiterminator
KEPPFGEB_02811 7.6e-110
KEPPFGEB_02812 1.2e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
KEPPFGEB_02813 1.3e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KEPPFGEB_02814 5.3e-195 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
KEPPFGEB_02815 1.9e-53 padR K Transcriptional regulator PadR-like family
KEPPFGEB_02816 2.2e-61 S Protein of unknown function (DUF2812)
KEPPFGEB_02819 3.1e-44 yxiJ S YxiJ-like protein
KEPPFGEB_02821 1.2e-34
KEPPFGEB_02822 6.5e-87 yxiI S Protein of unknown function (DUF2716)
KEPPFGEB_02823 2.3e-140
KEPPFGEB_02824 8.3e-13 yxiG
KEPPFGEB_02825 7.6e-16 yxiG
KEPPFGEB_02826 0.0 wapA M COG3209 Rhs family protein
KEPPFGEB_02827 7.4e-164 yxxF EG EamA-like transporter family
KEPPFGEB_02828 1.1e-72 yxiE T Belongs to the universal stress protein A family
KEPPFGEB_02829 6.9e-278 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KEPPFGEB_02830 1.8e-310 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KEPPFGEB_02831 5.5e-53
KEPPFGEB_02832 6.8e-218 S nuclease activity
KEPPFGEB_02833 4e-38 yxiC S Family of unknown function (DUF5344)
KEPPFGEB_02834 4.6e-21 S Domain of unknown function (DUF5082)
KEPPFGEB_02835 1.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KEPPFGEB_02836 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KEPPFGEB_02837 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
KEPPFGEB_02838 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KEPPFGEB_02839 4.4e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
KEPPFGEB_02840 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KEPPFGEB_02841 3.4e-250 lysP E amino acid
KEPPFGEB_02842 8.7e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KEPPFGEB_02843 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KEPPFGEB_02844 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KEPPFGEB_02845 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KEPPFGEB_02846 2.8e-151 yxxB S Domain of Unknown Function (DUF1206)
KEPPFGEB_02847 7.1e-198 eutH E Ethanolamine utilisation protein, EutH
KEPPFGEB_02848 5.6e-250 yxeQ S MmgE/PrpD family
KEPPFGEB_02849 1.4e-212 yxeP 3.5.1.47 E hydrolase activity
KEPPFGEB_02850 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
KEPPFGEB_02851 1.2e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
KEPPFGEB_02852 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
KEPPFGEB_02853 1.6e-93 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEPPFGEB_02854 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEPPFGEB_02855 1e-187 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KEPPFGEB_02856 6.2e-151 yidA S hydrolases of the HAD superfamily
KEPPFGEB_02859 1.3e-20 yxeE
KEPPFGEB_02860 5.6e-16 yxeD
KEPPFGEB_02861 8.5e-69
KEPPFGEB_02862 1.3e-176 fhuD P ABC transporter
KEPPFGEB_02863 1.5e-58 yxeA S Protein of unknown function (DUF1093)
KEPPFGEB_02864 0.0 yxdM V ABC transporter (permease)
KEPPFGEB_02865 9.4e-141 yxdL V ABC transporter, ATP-binding protein
KEPPFGEB_02866 2.2e-179 T PhoQ Sensor
KEPPFGEB_02867 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEPPFGEB_02868 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KEPPFGEB_02869 2.8e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KEPPFGEB_02870 8.6e-167 iolH G Xylose isomerase-like TIM barrel
KEPPFGEB_02871 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KEPPFGEB_02872 1.5e-234 iolF EGP Major facilitator Superfamily
KEPPFGEB_02873 2.3e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KEPPFGEB_02874 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KEPPFGEB_02875 3.5e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KEPPFGEB_02876 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KEPPFGEB_02877 3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEPPFGEB_02878 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
KEPPFGEB_02879 3.7e-176 iolS C Aldo keto reductase
KEPPFGEB_02881 4.1e-47 yxcD S Protein of unknown function (DUF2653)
KEPPFGEB_02882 2.1e-244 csbC EGP Major facilitator Superfamily
KEPPFGEB_02883 0.0 htpG O Molecular chaperone. Has ATPase activity
KEPPFGEB_02885 1.5e-149 IQ Enoyl-(Acyl carrier protein) reductase
KEPPFGEB_02886 1.9e-206 yxbF K Bacterial regulatory proteins, tetR family
KEPPFGEB_02887 4.2e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KEPPFGEB_02888 4.6e-20 yxaI S membrane protein domain
KEPPFGEB_02889 1.2e-92 S PQQ-like domain
KEPPFGEB_02890 8.7e-64 S Family of unknown function (DUF5391)
KEPPFGEB_02891 1.4e-75 yxaI S membrane protein domain
KEPPFGEB_02892 3.7e-224 P Protein of unknown function (DUF418)
KEPPFGEB_02893 1.6e-196 yxaG 1.13.11.24 S AraC-like ligand binding domain
KEPPFGEB_02894 6e-100 yxaF K Transcriptional regulator
KEPPFGEB_02895 6.8e-198 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEPPFGEB_02896 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
KEPPFGEB_02897 1.7e-48 S LrgA family
KEPPFGEB_02898 2.6e-118 yxaC M effector of murein hydrolase
KEPPFGEB_02899 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
KEPPFGEB_02900 8e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KEPPFGEB_02901 7.3e-127 gntR K transcriptional
KEPPFGEB_02902 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
KEPPFGEB_02903 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
KEPPFGEB_02904 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KEPPFGEB_02905 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KEPPFGEB_02906 3.8e-287 ahpF O Alkyl hydroperoxide reductase
KEPPFGEB_02907 5.6e-189 wgaE S Polysaccharide pyruvyl transferase
KEPPFGEB_02908 7e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KEPPFGEB_02909 7.2e-16 bglF G phosphotransferase system
KEPPFGEB_02910 1.6e-123 yydK K Transcriptional regulator
KEPPFGEB_02911 7.6e-13
KEPPFGEB_02912 1.6e-118 S ABC-2 family transporter protein
KEPPFGEB_02913 1e-108 prrC P ABC transporter
KEPPFGEB_02914 1.6e-132 yydH O Peptidase M50
KEPPFGEB_02915 2.2e-184 S Radical SAM superfamily
KEPPFGEB_02916 8e-12
KEPPFGEB_02917 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
KEPPFGEB_02919 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KEPPFGEB_02920 1.1e-09 S YyzF-like protein
KEPPFGEB_02921 3.8e-64
KEPPFGEB_02922 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KEPPFGEB_02924 1.1e-29 yycQ S Protein of unknown function (DUF2651)
KEPPFGEB_02925 2.7e-208 yycP
KEPPFGEB_02926 2.9e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KEPPFGEB_02927 2.9e-84 yycN 2.3.1.128 K Acetyltransferase
KEPPFGEB_02928 1.5e-187 S aspartate phosphatase
KEPPFGEB_02930 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KEPPFGEB_02931 1e-254 rocE E amino acid
KEPPFGEB_02932 2.1e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KEPPFGEB_02933 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KEPPFGEB_02934 7.9e-173 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
KEPPFGEB_02935 1.5e-94 K PFAM response regulator receiver
KEPPFGEB_02936 3e-74 S Peptidase propeptide and YPEB domain
KEPPFGEB_02937 1.1e-30 S Peptidase propeptide and YPEB domain
KEPPFGEB_02938 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KEPPFGEB_02939 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KEPPFGEB_02940 1.1e-153 yycI S protein conserved in bacteria
KEPPFGEB_02941 1.9e-256 yycH S protein conserved in bacteria
KEPPFGEB_02942 0.0 vicK 2.7.13.3 T Histidine kinase
KEPPFGEB_02943 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEPPFGEB_02948 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KEPPFGEB_02949 4e-77 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEPPFGEB_02950 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KEPPFGEB_02951 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
KEPPFGEB_02953 1.9e-15 yycC K YycC-like protein
KEPPFGEB_02954 4.2e-220 yeaN P COG2807 Cyanate permease
KEPPFGEB_02955 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KEPPFGEB_02956 2.2e-73 rplI J binds to the 23S rRNA
KEPPFGEB_02957 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KEPPFGEB_02958 2.9e-160 yybS S membrane
KEPPFGEB_02960 3.9e-84 cotF M Spore coat protein
KEPPFGEB_02961 1.4e-68 ydeP3 K Transcriptional regulator
KEPPFGEB_02962 4.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KEPPFGEB_02963 1.1e-69
KEPPFGEB_02965 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
KEPPFGEB_02966 1.3e-110 K TipAS antibiotic-recognition domain
KEPPFGEB_02967 3.8e-121
KEPPFGEB_02968 1.5e-65 yybH S SnoaL-like domain
KEPPFGEB_02969 1.1e-121 yybG S Pentapeptide repeat-containing protein
KEPPFGEB_02970 1.1e-217 ynfM EGP Major facilitator Superfamily
KEPPFGEB_02971 6.9e-164 yybE K Transcriptional regulator
KEPPFGEB_02972 3.2e-77 yjcF S Acetyltransferase (GNAT) domain
KEPPFGEB_02973 8e-74 yybC
KEPPFGEB_02974 1.6e-125 S Metallo-beta-lactamase superfamily
KEPPFGEB_02975 5.6e-77 yybA 2.3.1.57 K transcriptional
KEPPFGEB_02976 5.4e-72 yjcF S Acetyltransferase (GNAT) domain
KEPPFGEB_02977 1.4e-96 yyaS S Membrane
KEPPFGEB_02978 2.7e-91 yyaR K Acetyltransferase (GNAT) domain
KEPPFGEB_02979 5.6e-64 yyaQ S YjbR
KEPPFGEB_02980 3.8e-107 yyaP 1.5.1.3 H RibD C-terminal domain
KEPPFGEB_02981 6.7e-22 yyaR K acetyltransferase
KEPPFGEB_02982 5.1e-61 yyaN K MerR HTH family regulatory protein
KEPPFGEB_02983 3.5e-158 yyaM EG EamA-like transporter family
KEPPFGEB_02984 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KEPPFGEB_02985 1.5e-166 yyaK S CAAX protease self-immunity
KEPPFGEB_02986 2.7e-244 EGP Major facilitator superfamily
KEPPFGEB_02987 2.4e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
KEPPFGEB_02988 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEPPFGEB_02989 5.6e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
KEPPFGEB_02990 4e-144 xth 3.1.11.2 L exodeoxyribonuclease III
KEPPFGEB_02991 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KEPPFGEB_02992 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KEPPFGEB_02993 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
KEPPFGEB_02994 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KEPPFGEB_02995 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KEPPFGEB_02996 2.3e-33 yyzM S protein conserved in bacteria
KEPPFGEB_02997 8.1e-177 yyaD S Membrane
KEPPFGEB_02998 2.8e-111 yyaC S Sporulation protein YyaC
KEPPFGEB_02999 2.1e-149 spo0J K Belongs to the ParB family
KEPPFGEB_03000 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
KEPPFGEB_03001 1.5e-74 S Bacterial PH domain
KEPPFGEB_03002 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KEPPFGEB_03003 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KEPPFGEB_03004 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KEPPFGEB_03005 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KEPPFGEB_03006 2.5e-107 jag S single-stranded nucleic acid binding R3H
KEPPFGEB_03007 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KEPPFGEB_03008 1.2e-53 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KEPPFGEB_03009 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KEPPFGEB_03010 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KEPPFGEB_03011 2.4e-33 yaaA S S4 domain
KEPPFGEB_03012 1e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KEPPFGEB_03013 4e-37 yaaB S Domain of unknown function (DUF370)
KEPPFGEB_03014 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KEPPFGEB_03015 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KEPPFGEB_03018 2e-08
KEPPFGEB_03025 1.3e-09
KEPPFGEB_03026 7.8e-08
KEPPFGEB_03035 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KEPPFGEB_03036 6.8e-196 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KEPPFGEB_03037 4.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
KEPPFGEB_03038 7.9e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KEPPFGEB_03039 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KEPPFGEB_03040 1.9e-75 tspO T membrane
KEPPFGEB_03041 7.4e-205 cotI S Spore coat protein
KEPPFGEB_03042 7.7e-216 cotSA M Glycosyl transferases group 1
KEPPFGEB_03043 1.3e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
KEPPFGEB_03045 8.2e-232 ytcC M Glycosyltransferase Family 4
KEPPFGEB_03046 2.6e-177 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
KEPPFGEB_03047 2.2e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KEPPFGEB_03048 2.5e-152 galU 2.7.7.9 M Nucleotidyl transferase
KEPPFGEB_03049 2.6e-132 dksA T COG1734 DnaK suppressor protein
KEPPFGEB_03050 2.1e-271 menF 5.4.4.2 HQ Isochorismate synthase
KEPPFGEB_03051 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KEPPFGEB_03052 1.1e-152 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KEPPFGEB_03053 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KEPPFGEB_03054 5.7e-272 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KEPPFGEB_03055 4.6e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KEPPFGEB_03056 3.3e-169 troA P Belongs to the bacterial solute-binding protein 9 family
KEPPFGEB_03057 3.6e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KEPPFGEB_03058 2.4e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KEPPFGEB_03059 1.7e-149 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
KEPPFGEB_03060 1.1e-24 S Domain of Unknown Function (DUF1540)
KEPPFGEB_03061 4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KEPPFGEB_03062 1.8e-248 cydA 1.10.3.14 C oxidase, subunit
KEPPFGEB_03063 3.6e-41 rpmE2 J Ribosomal protein L31
KEPPFGEB_03064 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KEPPFGEB_03065 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KEPPFGEB_03066 4.5e-71 ytkA S YtkA-like
KEPPFGEB_03068 2.1e-76 dps P Belongs to the Dps family
KEPPFGEB_03069 7e-63 ytkC S Bacteriophage holin family
KEPPFGEB_03070 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
KEPPFGEB_03071 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KEPPFGEB_03072 1.4e-144 ytlC P ABC transporter
KEPPFGEB_03073 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KEPPFGEB_03074 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KEPPFGEB_03075 1.2e-38 ytmB S Protein of unknown function (DUF2584)
KEPPFGEB_03076 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KEPPFGEB_03077 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KEPPFGEB_03078 0.0 asnB 6.3.5.4 E Asparagine synthase
KEPPFGEB_03079 2.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
KEPPFGEB_03080 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KEPPFGEB_03081 4.2e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
KEPPFGEB_03082 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KEPPFGEB_03083 2.8e-105 ytqB J Putative rRNA methylase
KEPPFGEB_03084 8.1e-190 yhcC S Fe-S oxidoreductase
KEPPFGEB_03085 6.7e-41 ytzC S Protein of unknown function (DUF2524)
KEPPFGEB_03087 5.1e-66 ytrA K GntR family transcriptional regulator
KEPPFGEB_03088 4.2e-161 ytrB P abc transporter atp-binding protein
KEPPFGEB_03089 2e-164 P ABC-2 family transporter protein
KEPPFGEB_03090 7e-149
KEPPFGEB_03091 2.6e-126 ytrE V ABC transporter, ATP-binding protein
KEPPFGEB_03092 2.1e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
KEPPFGEB_03093 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEPPFGEB_03094 4e-184 T PhoQ Sensor
KEPPFGEB_03095 1.3e-137 bceA V ABC transporter, ATP-binding protein
KEPPFGEB_03096 0.0 bceB V ABC transporter (permease)
KEPPFGEB_03097 1.3e-41 yttA 2.7.13.3 S Pfam Transposase IS66
KEPPFGEB_03098 1.3e-210 yttB EGP Major facilitator Superfamily
KEPPFGEB_03099 5.6e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KEPPFGEB_03100 7.7e-55 ytvB S Protein of unknown function (DUF4257)
KEPPFGEB_03101 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KEPPFGEB_03102 2.1e-51 ytwF P Sulfurtransferase
KEPPFGEB_03103 1.3e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KEPPFGEB_03104 4.4e-144 amyC P ABC transporter (permease)
KEPPFGEB_03105 6.2e-168 amyD P ABC transporter
KEPPFGEB_03106 1.5e-244 msmE G Bacterial extracellular solute-binding protein
KEPPFGEB_03107 2.5e-189 msmR K Transcriptional regulator
KEPPFGEB_03108 9.2e-172 ytaP S Acetyl xylan esterase (AXE1)
KEPPFGEB_03109 3.8e-139 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KEPPFGEB_03110 2.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KEPPFGEB_03111 2.5e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KEPPFGEB_03112 1.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KEPPFGEB_03113 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KEPPFGEB_03114 3.5e-219 bioI 1.14.14.46 C Cytochrome P450
KEPPFGEB_03115 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
KEPPFGEB_03116 4.2e-145 ytcP G COG0395 ABC-type sugar transport system, permease component
KEPPFGEB_03117 2.4e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
KEPPFGEB_03118 0.0 ytdP K Transcriptional regulator
KEPPFGEB_03119 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KEPPFGEB_03120 1.1e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
KEPPFGEB_03121 3.3e-71 yteS G transport
KEPPFGEB_03122 5e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
KEPPFGEB_03123 3.4e-115 yteU S Integral membrane protein
KEPPFGEB_03124 3.1e-26 yteV S Sporulation protein Cse60
KEPPFGEB_03125 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KEPPFGEB_03126 8.2e-232 ytfP S HI0933-like protein
KEPPFGEB_03127 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEPPFGEB_03128 1.1e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KEPPFGEB_03129 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KEPPFGEB_03130 1.4e-130 ythP V ABC transporter
KEPPFGEB_03131 5.4e-201 ythQ U Bacterial ABC transporter protein EcsB
KEPPFGEB_03132 2.1e-225 pbuO S permease
KEPPFGEB_03133 6.6e-270 pepV 3.5.1.18 E Dipeptidase
KEPPFGEB_03134 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KEPPFGEB_03135 8.9e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KEPPFGEB_03136 1.3e-165 ytlQ
KEPPFGEB_03137 2.5e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KEPPFGEB_03138 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KEPPFGEB_03139 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
KEPPFGEB_03140 2e-45 ytzH S YtzH-like protein
KEPPFGEB_03141 2.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KEPPFGEB_03142 7.1e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KEPPFGEB_03143 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
KEPPFGEB_03144 8.3e-51 ytzB S small secreted protein
KEPPFGEB_03145 1.2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KEPPFGEB_03146 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
KEPPFGEB_03147 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KEPPFGEB_03148 9.8e-149 ytpQ S Belongs to the UPF0354 family
KEPPFGEB_03149 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KEPPFGEB_03150 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KEPPFGEB_03151 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KEPPFGEB_03152 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KEPPFGEB_03153 6.6e-17 ytxH S COG4980 Gas vesicle protein
KEPPFGEB_03154 1.7e-54 ytxJ O Protein of unknown function (DUF2847)
KEPPFGEB_03155 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KEPPFGEB_03156 1.7e-182 ccpA K catabolite control protein A
KEPPFGEB_03157 2.1e-146 motA N flagellar motor
KEPPFGEB_03158 1.4e-125 motS N Flagellar motor protein
KEPPFGEB_03159 8e-224 acuC BQ histone deacetylase
KEPPFGEB_03160 2.1e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
KEPPFGEB_03161 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KEPPFGEB_03162 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KEPPFGEB_03163 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KEPPFGEB_03165 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KEPPFGEB_03166 2.6e-308 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KEPPFGEB_03167 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KEPPFGEB_03168 1e-108 yttP K Transcriptional regulator
KEPPFGEB_03169 2.7e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KEPPFGEB_03170 2.7e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KEPPFGEB_03171 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
KEPPFGEB_03172 5e-207 iscS2 2.8.1.7 E Cysteine desulfurase
KEPPFGEB_03173 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KEPPFGEB_03174 2e-29 sspB S spore protein
KEPPFGEB_03175 2.9e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KEPPFGEB_03176 0.0 ytcJ S amidohydrolase
KEPPFGEB_03177 8.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KEPPFGEB_03178 1e-179 sppA OU signal peptide peptidase SppA
KEPPFGEB_03179 2.5e-86 yteJ S RDD family
KEPPFGEB_03180 1.6e-110 ytfI S Protein of unknown function (DUF2953)
KEPPFGEB_03181 8.7e-70 ytfJ S Sporulation protein YtfJ
KEPPFGEB_03182 7.1e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KEPPFGEB_03183 1.6e-164 ytxK 2.1.1.72 L DNA methylase
KEPPFGEB_03184 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KEPPFGEB_03185 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KEPPFGEB_03186 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KEPPFGEB_03187 8.9e-267 argH 4.3.2.1 E argininosuccinate lyase
KEPPFGEB_03189 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEPPFGEB_03190 1.7e-130 ytkL S Belongs to the UPF0173 family
KEPPFGEB_03191 8e-241 ytoI K transcriptional regulator containing CBS domains
KEPPFGEB_03192 2.4e-47 ytpI S YtpI-like protein
KEPPFGEB_03193 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KEPPFGEB_03194 9.2e-29
KEPPFGEB_03195 8.2e-69 ytrI
KEPPFGEB_03196 3.2e-56 ytrH S Sporulation protein YtrH
KEPPFGEB_03197 0.0 dnaE 2.7.7.7 L DNA polymerase
KEPPFGEB_03198 3.4e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
KEPPFGEB_03199 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KEPPFGEB_03200 5.6e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KEPPFGEB_03201 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KEPPFGEB_03202 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KEPPFGEB_03203 4.3e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
KEPPFGEB_03204 2.6e-192 ytvI S sporulation integral membrane protein YtvI
KEPPFGEB_03205 4.7e-71 yeaL S membrane
KEPPFGEB_03206 1.1e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
KEPPFGEB_03207 9.1e-242 icd 1.1.1.42 C isocitrate
KEPPFGEB_03208 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KEPPFGEB_03209 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEPPFGEB_03210 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KEPPFGEB_03211 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KEPPFGEB_03212 7.8e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KEPPFGEB_03213 1.1e-107 ytaF P Probably functions as a manganese efflux pump
KEPPFGEB_03214 8.4e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KEPPFGEB_03215 8.9e-161 ytbE S reductase
KEPPFGEB_03216 2.4e-204 ytbD EGP Major facilitator Superfamily
KEPPFGEB_03217 4.9e-66 ytcD K Transcriptional regulator
KEPPFGEB_03218 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KEPPFGEB_03219 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KEPPFGEB_03220 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KEPPFGEB_03221 2.2e-265 dnaB L Membrane attachment protein
KEPPFGEB_03222 2.5e-172 dnaI L Primosomal protein DnaI
KEPPFGEB_03223 4.6e-109 ytxB S SNARE associated Golgi protein
KEPPFGEB_03224 1.4e-158 ytxC S YtxC-like family
KEPPFGEB_03226 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KEPPFGEB_03227 2.8e-148 ysaA S HAD-hyrolase-like
KEPPFGEB_03228 0.0 lytS 2.7.13.3 T Histidine kinase
KEPPFGEB_03229 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
KEPPFGEB_03230 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KEPPFGEB_03231 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KEPPFGEB_03233 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KEPPFGEB_03234 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KEPPFGEB_03235 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KEPPFGEB_03236 2.2e-44 ysdA S Membrane
KEPPFGEB_03237 3.5e-67 ysdB S Sigma-w pathway protein YsdB
KEPPFGEB_03238 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
KEPPFGEB_03239 2.6e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KEPPFGEB_03240 7.8e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KEPPFGEB_03241 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
KEPPFGEB_03242 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KEPPFGEB_03243 6.6e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KEPPFGEB_03244 3.7e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KEPPFGEB_03245 6.2e-254 araN G carbohydrate transport
KEPPFGEB_03246 1.4e-167 araP G carbohydrate transport
KEPPFGEB_03247 3.4e-144 araQ G transport system permease
KEPPFGEB_03248 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
KEPPFGEB_03249 0.0 cstA T Carbon starvation protein
KEPPFGEB_03250 4.5e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
KEPPFGEB_03251 1.1e-256 glcF C Glycolate oxidase
KEPPFGEB_03252 7.5e-261 glcD 1.1.3.15 C Glycolate oxidase subunit
KEPPFGEB_03253 1.9e-203 ysfB KT regulator
KEPPFGEB_03254 5.8e-32 sspI S Belongs to the SspI family
KEPPFGEB_03255 7.7e-132 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KEPPFGEB_03256 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KEPPFGEB_03257 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KEPPFGEB_03258 9e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KEPPFGEB_03259 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KEPPFGEB_03260 1.7e-85 cvpA S membrane protein, required for colicin V production
KEPPFGEB_03261 0.0 polX L COG1796 DNA polymerase IV (family X)
KEPPFGEB_03262 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KEPPFGEB_03263 7.3e-68 yshE S membrane
KEPPFGEB_03264 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KEPPFGEB_03265 2.7e-100 fadR K Transcriptional regulator
KEPPFGEB_03266 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KEPPFGEB_03267 2.9e-134 etfB C Electron transfer flavoprotein
KEPPFGEB_03268 5.5e-178 etfA C Electron transfer flavoprotein
KEPPFGEB_03270 2.6e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
KEPPFGEB_03271 2e-52 trxA O Belongs to the thioredoxin family
KEPPFGEB_03272 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KEPPFGEB_03273 3.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KEPPFGEB_03274 1.2e-79 yslB S Protein of unknown function (DUF2507)
KEPPFGEB_03275 2.4e-107 sdhC C succinate dehydrogenase
KEPPFGEB_03276 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KEPPFGEB_03277 1.7e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KEPPFGEB_03278 1.9e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
KEPPFGEB_03279 3.3e-30 gerE K Transcriptional regulator
KEPPFGEB_03280 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
KEPPFGEB_03281 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KEPPFGEB_03282 5e-196 gerM S COG5401 Spore germination protein
KEPPFGEB_03283 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KEPPFGEB_03284 2.9e-102 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KEPPFGEB_03285 4.1e-92 ysnB S Phosphoesterase
KEPPFGEB_03287 1.7e-132 ysnF S protein conserved in bacteria
KEPPFGEB_03288 5.7e-77 ysnE K acetyltransferase
KEPPFGEB_03290 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KEPPFGEB_03291 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
KEPPFGEB_03292 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KEPPFGEB_03293 2.9e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KEPPFGEB_03294 1.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KEPPFGEB_03295 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KEPPFGEB_03296 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KEPPFGEB_03297 1.6e-185 ysoA H Tetratricopeptide repeat
KEPPFGEB_03298 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KEPPFGEB_03299 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KEPPFGEB_03300 1.7e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
KEPPFGEB_03301 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KEPPFGEB_03302 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
KEPPFGEB_03303 5.4e-89 ysxD
KEPPFGEB_03304 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KEPPFGEB_03305 3.6e-146 hemX O cytochrome C
KEPPFGEB_03306 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KEPPFGEB_03307 3.5e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KEPPFGEB_03308 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
KEPPFGEB_03309 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KEPPFGEB_03310 1.9e-221 spoVID M stage VI sporulation protein D
KEPPFGEB_03311 1.7e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KEPPFGEB_03312 1.6e-25
KEPPFGEB_03313 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KEPPFGEB_03314 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KEPPFGEB_03315 1.4e-125 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KEPPFGEB_03316 6.4e-166 spoIIB S Sporulation related domain
KEPPFGEB_03317 1.1e-101 maf D septum formation protein Maf
KEPPFGEB_03318 7.7e-126 radC E Belongs to the UPF0758 family
KEPPFGEB_03319 1.8e-184 mreB D Rod shape-determining protein MreB
KEPPFGEB_03320 1.1e-156 mreC M Involved in formation and maintenance of cell shape
KEPPFGEB_03321 1.4e-84 mreD M shape-determining protein
KEPPFGEB_03322 7.1e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KEPPFGEB_03323 8e-143 minD D Belongs to the ParA family
KEPPFGEB_03324 8.5e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KEPPFGEB_03325 2.7e-160 spoIVFB S Stage IV sporulation protein
KEPPFGEB_03326 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KEPPFGEB_03327 4.1e-56 ysxB J ribosomal protein
KEPPFGEB_03328 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KEPPFGEB_03329 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KEPPFGEB_03330 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KEPPFGEB_03331 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
KEPPFGEB_03332 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
KEPPFGEB_03333 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
KEPPFGEB_03334 1.3e-229 nifS 2.8.1.7 E Cysteine desulfurase
KEPPFGEB_03335 2.9e-301 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KEPPFGEB_03336 2.3e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KEPPFGEB_03337 1.2e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KEPPFGEB_03338 8.3e-157 safA M spore coat assembly protein SafA
KEPPFGEB_03339 1.7e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KEPPFGEB_03340 5.5e-127 yebC K transcriptional regulatory protein
KEPPFGEB_03341 3.1e-262 alsT E Sodium alanine symporter
KEPPFGEB_03342 3.1e-51 S Family of unknown function (DUF5412)
KEPPFGEB_03344 1.6e-117 yrzF T serine threonine protein kinase
KEPPFGEB_03345 1.7e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
KEPPFGEB_03346 1e-251 csbX EGP Major facilitator Superfamily
KEPPFGEB_03347 1.1e-92 bofC S BofC C-terminal domain
KEPPFGEB_03348 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KEPPFGEB_03349 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KEPPFGEB_03350 2.6e-18 yrzS S Protein of unknown function (DUF2905)
KEPPFGEB_03351 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KEPPFGEB_03352 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KEPPFGEB_03353 1.1e-38 yajC U Preprotein translocase subunit YajC
KEPPFGEB_03354 2.2e-73 yrzE S Protein of unknown function (DUF3792)
KEPPFGEB_03355 1.3e-111 yrbG S membrane
KEPPFGEB_03356 5.3e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEPPFGEB_03357 1.6e-48 yrzD S Post-transcriptional regulator
KEPPFGEB_03358 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KEPPFGEB_03359 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
KEPPFGEB_03360 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
KEPPFGEB_03361 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KEPPFGEB_03362 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KEPPFGEB_03363 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KEPPFGEB_03364 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KEPPFGEB_03365 1.1e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
KEPPFGEB_03367 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
KEPPFGEB_03368 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KEPPFGEB_03369 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KEPPFGEB_03370 1.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KEPPFGEB_03371 1.2e-70 cymR K Transcriptional regulator
KEPPFGEB_03372 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
KEPPFGEB_03373 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KEPPFGEB_03374 1.4e-15 S COG0457 FOG TPR repeat
KEPPFGEB_03375 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KEPPFGEB_03376 1.2e-82 yrrD S protein conserved in bacteria
KEPPFGEB_03377 9.8e-31 yrzR
KEPPFGEB_03378 8e-08 S Protein of unknown function (DUF3918)
KEPPFGEB_03379 7.6e-107 glnP P ABC transporter
KEPPFGEB_03380 1.8e-108 gluC P ABC transporter
KEPPFGEB_03381 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
KEPPFGEB_03382 3.2e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KEPPFGEB_03383 2.7e-170 yrrI S AI-2E family transporter
KEPPFGEB_03384 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KEPPFGEB_03385 1.7e-41 yrzL S Belongs to the UPF0297 family
KEPPFGEB_03386 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KEPPFGEB_03387 1.2e-45 yrzB S Belongs to the UPF0473 family
KEPPFGEB_03388 3.7e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KEPPFGEB_03389 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
KEPPFGEB_03390 7.3e-172 yegQ O Peptidase U32
KEPPFGEB_03391 2.7e-246 yegQ O COG0826 Collagenase and related proteases
KEPPFGEB_03392 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KEPPFGEB_03393 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KEPPFGEB_03394 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
KEPPFGEB_03395 4.2e-63 yrrS S Protein of unknown function (DUF1510)
KEPPFGEB_03396 1e-25 yrzA S Protein of unknown function (DUF2536)
KEPPFGEB_03397 1.9e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KEPPFGEB_03398 1.2e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KEPPFGEB_03399 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KEPPFGEB_03400 5.9e-208 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KEPPFGEB_03401 5.4e-78 yrhD S Protein of unknown function (DUF1641)
KEPPFGEB_03402 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KEPPFGEB_03403 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
KEPPFGEB_03404 3e-142 focA P Formate nitrite
KEPPFGEB_03406 1.1e-95 yrhH Q methyltransferase
KEPPFGEB_03407 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
KEPPFGEB_03408 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KEPPFGEB_03409 4.3e-168 capL C PFAM UDP-glucose GDP-mannose dehydrogenase
KEPPFGEB_03410 2.6e-119 wbpP 5.1.3.2, 5.1.3.7 GM NmrA-like family
KEPPFGEB_03411 9.4e-117 S ATPases associated with a variety of cellular activities
KEPPFGEB_03412 5.7e-64 S ABC-2 family transporter protein
KEPPFGEB_03413 8.3e-63 S ABC-2 family transporter protein
KEPPFGEB_03414 7.2e-104 Q TIGRFAM amino acid adenylation domain
KEPPFGEB_03415 2e-46 hopR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KEPPFGEB_03416 6.6e-181 hutH 4.3.1.23, 4.3.1.24, 4.3.1.3, 5.4.3.6 E Aromatic amino acid lyase
KEPPFGEB_03417 2.6e-100 EF ATP-grasp domain
KEPPFGEB_03418 6.6e-88 yodQ 3.5.1.16 E Acetylornithine deacetylase
KEPPFGEB_03419 1.5e-52 S dehydrogenases and related proteins
KEPPFGEB_03420 3.9e-11 O Butirosin biosynthesis protein H, N-terminal
KEPPFGEB_03421 7.3e-29 S Butirosin biosynthesis protein H, N-terminal
KEPPFGEB_03422 3.2e-17 yrhK S YrhK-like protein
KEPPFGEB_03423 0.0 yrhL I Acyltransferase family
KEPPFGEB_03424 1e-148 rsiV S Protein of unknown function (DUF3298)
KEPPFGEB_03425 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KEPPFGEB_03426 7e-150 yrhO K Archaeal transcriptional regulator TrmB
KEPPFGEB_03427 1.1e-105 yrhP E LysE type translocator
KEPPFGEB_03428 6.6e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KEPPFGEB_03429 0.0 levR K PTS system fructose IIA component
KEPPFGEB_03430 8.7e-75 levD 2.7.1.202 G PTS system fructose IIA component
KEPPFGEB_03431 4.1e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
KEPPFGEB_03432 4.4e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KEPPFGEB_03433 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KEPPFGEB_03434 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KEPPFGEB_03435 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
KEPPFGEB_03436 2.5e-197 adhA 1.1.1.1 C alcohol dehydrogenase
KEPPFGEB_03437 4e-24 yphJ 4.1.1.44 S peroxiredoxin activity
KEPPFGEB_03438 4.3e-47 yraB K helix_turn_helix, mercury resistance
KEPPFGEB_03439 1.1e-49 yraD M Spore coat protein
KEPPFGEB_03440 1.7e-25 yraE
KEPPFGEB_03441 1.1e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KEPPFGEB_03442 6.4e-63 yraF M Spore coat protein
KEPPFGEB_03443 5.3e-37 yraG
KEPPFGEB_03444 1.3e-66 E Glyoxalase-like domain
KEPPFGEB_03445 3.2e-61 T sh3 domain protein
KEPPFGEB_03446 1.7e-60 T sh3 domain protein
KEPPFGEB_03447 9.9e-149 S Alpha beta hydrolase
KEPPFGEB_03448 4.2e-40 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEPPFGEB_03449 2e-149 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KEPPFGEB_03450 6.5e-204 yraM S PrpF protein
KEPPFGEB_03451 3.7e-162 yraN K Transcriptional regulator
KEPPFGEB_03452 1.1e-221 yraO C Citrate transporter
KEPPFGEB_03453 1.9e-186 yrpG C Aldo/keto reductase family
KEPPFGEB_03454 2.3e-93 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
KEPPFGEB_03455 3e-115 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KEPPFGEB_03456 5.1e-65 napB K MarR family transcriptional regulator
KEPPFGEB_03457 5.2e-214 yfjF U Belongs to the major facilitator superfamily
KEPPFGEB_03459 1.8e-137 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
KEPPFGEB_03460 7.7e-153 2.2.1.1 G Transketolase, pyrimidine binding domain
KEPPFGEB_03461 1.1e-112 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEPPFGEB_03462 3e-211 rbtT P Major Facilitator Superfamily
KEPPFGEB_03464 2.5e-100 K helix_turn_helix gluconate operon transcriptional repressor
KEPPFGEB_03465 8.7e-125 yrpD S Domain of unknown function, YrpD
KEPPFGEB_03466 5.1e-142 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KEPPFGEB_03467 7.3e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KEPPFGEB_03468 2.3e-161 aadK G Streptomycin adenylyltransferase
KEPPFGEB_03469 2.6e-91 yrdA S DinB family
KEPPFGEB_03470 7.2e-40
KEPPFGEB_03471 7.7e-29
KEPPFGEB_03472 1.5e-54 S Protein of unknown function (DUF2568)
KEPPFGEB_03473 5e-99 yrdC 3.5.1.19 Q Isochorismatase family
KEPPFGEB_03474 3.6e-227 cypA C Cytochrome P450
KEPPFGEB_03476 2.6e-40 yrdF K ribonuclease inhibitor
KEPPFGEB_03477 5.3e-78 bkdR K helix_turn_helix ASNC type
KEPPFGEB_03478 2.8e-137 azlC E AzlC protein
KEPPFGEB_03479 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
KEPPFGEB_03480 9.5e-226 brnQ E Component of the transport system for branched-chain amino acids
KEPPFGEB_03481 7.7e-153 czcD P COG1230 Co Zn Cd efflux system component
KEPPFGEB_03482 3.3e-197 trkA P Oxidoreductase
KEPPFGEB_03483 3.3e-158 yrdQ K Transcriptional regulator
KEPPFGEB_03484 6e-169 yrdR EG EamA-like transporter family
KEPPFGEB_03485 8.7e-16 S YrzO-like protein
KEPPFGEB_03486 2.8e-230 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KEPPFGEB_03487 9.1e-83 bltD 2.3.1.57 K FR47-like protein
KEPPFGEB_03488 5.6e-209 blt EGP Major facilitator Superfamily
KEPPFGEB_03489 3.1e-150 bltR K helix_turn_helix, mercury resistance
KEPPFGEB_03490 4.6e-105 yrkC G Cupin domain
KEPPFGEB_03491 8.6e-21
KEPPFGEB_03492 7.8e-39 yrkD S protein conserved in bacteria
KEPPFGEB_03493 6.2e-82 yrkE O DsrE/DsrF/DrsH-like family
KEPPFGEB_03494 1e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
KEPPFGEB_03496 7.6e-208 yrkH P Rhodanese Homology Domain
KEPPFGEB_03497 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
KEPPFGEB_03498 2.2e-100 yrkJ S membrane transporter protein
KEPPFGEB_03499 3.1e-78 S Protein of unknown function with HXXEE motif
KEPPFGEB_03500 1.5e-97 ywrO S Flavodoxin-like fold
KEPPFGEB_03501 2.3e-104 yrkN K Acetyltransferase (GNAT) family
KEPPFGEB_03502 1.4e-223 yrkO P Protein of unknown function (DUF418)
KEPPFGEB_03503 4.1e-127 T Transcriptional regulator
KEPPFGEB_03504 1.3e-235 yrkQ T Histidine kinase
KEPPFGEB_03505 2e-68 psiE S Protein PsiE homolog
KEPPFGEB_03506 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEPPFGEB_03507 4.4e-94 yqaB E IrrE N-terminal-like domain
KEPPFGEB_03508 1e-101 adk 2.7.4.3 F adenylate kinase activity
KEPPFGEB_03510 1.1e-56 K sequence-specific DNA binding
KEPPFGEB_03511 6.5e-37 K Helix-turn-helix XRE-family like proteins
KEPPFGEB_03513 4.4e-103
KEPPFGEB_03517 4.9e-163 yqaJ L YqaJ-like viral recombinase domain
KEPPFGEB_03518 4.1e-137 recT L RecT family
KEPPFGEB_03519 6.4e-176 xkdC L IstB-like ATP binding protein
KEPPFGEB_03521 4.3e-53 rusA L Endodeoxyribonuclease RusA
KEPPFGEB_03522 2.4e-30 yqaO S Phage-like element PBSX protein XtrA
KEPPFGEB_03523 1.5e-06
KEPPFGEB_03524 3.7e-76 L Transposase
KEPPFGEB_03526 1.5e-95 yqaS L DNA packaging
KEPPFGEB_03527 2.1e-246 S phage terminase, large subunit
KEPPFGEB_03528 6.3e-290 yqbA S portal protein
KEPPFGEB_03529 1.4e-151 S Phage Mu protein F like protein
KEPPFGEB_03531 8.8e-120 yqbD 2.1.1.72 L Putative phage serine protease XkdF
KEPPFGEB_03532 4.6e-166 xkdG S Phage capsid family
KEPPFGEB_03533 6.7e-45 S YqbF, hypothetical protein domain
KEPPFGEB_03534 4.6e-67 S Protein of unknown function (DUF3199)
KEPPFGEB_03535 6.3e-63 yqbH S Domain of unknown function (DUF3599)
KEPPFGEB_03536 5.6e-86 S Bacteriophage HK97-gp10, putative tail-component
KEPPFGEB_03537 6.6e-75
KEPPFGEB_03538 4.6e-25
KEPPFGEB_03539 7.4e-253 xkdK S Phage tail sheath C-terminal domain
KEPPFGEB_03540 3.9e-75 xkdM S Phage tail tube protein
KEPPFGEB_03542 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
KEPPFGEB_03543 0.0 xkdO L Transglycosylase SLT domain
KEPPFGEB_03544 9e-114 xkdP S Lysin motif
KEPPFGEB_03545 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
KEPPFGEB_03546 1.8e-38 xkdR S Protein of unknown function (DUF2577)
KEPPFGEB_03547 9.6e-71 xkdS S Protein of unknown function (DUF2634)
KEPPFGEB_03548 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KEPPFGEB_03549 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KEPPFGEB_03550 9.6e-40
KEPPFGEB_03551 5.9e-221
KEPPFGEB_03552 4.1e-56 xkdW S XkdW protein
KEPPFGEB_03553 1.3e-23
KEPPFGEB_03554 4.8e-165 xepA
KEPPFGEB_03555 2.6e-68 S Bacteriophage holin family
KEPPFGEB_03556 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KEPPFGEB_03558 5e-60
KEPPFGEB_03560 5.3e-104 S Suppressor of fused protein (SUFU)
KEPPFGEB_03561 3.3e-273 A Pre-toxin TG
KEPPFGEB_03562 1.7e-27
KEPPFGEB_03564 2.1e-64 S response regulator aspartate phosphatase
KEPPFGEB_03566 5.1e-99 yrkC G Cupin domain
KEPPFGEB_03568 3.8e-41 K cell wall organization
KEPPFGEB_03569 4.5e-91 M Glycosyltransferase like family
KEPPFGEB_03570 6.9e-114 H Methionine biosynthesis protein MetW
KEPPFGEB_03571 6.8e-185 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KEPPFGEB_03572 5.3e-219 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
KEPPFGEB_03573 1.5e-41 S Spore coat protein Z
KEPPFGEB_03574 1.4e-38 S Protein of unknown function (DUF3992)
KEPPFGEB_03576 2.1e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
KEPPFGEB_03577 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KEPPFGEB_03578 1.2e-84 gerD
KEPPFGEB_03579 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KEPPFGEB_03580 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KEPPFGEB_03581 9.7e-66 ybaK S Protein of unknown function (DUF2521)
KEPPFGEB_03582 3.4e-143 ybaJ Q Methyltransferase domain
KEPPFGEB_03583 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KEPPFGEB_03584 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KEPPFGEB_03585 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KEPPFGEB_03586 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KEPPFGEB_03587 1.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KEPPFGEB_03588 1.6e-154 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KEPPFGEB_03589 3.6e-58 rplQ J Ribosomal protein L17
KEPPFGEB_03590 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEPPFGEB_03591 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KEPPFGEB_03592 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KEPPFGEB_03593 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KEPPFGEB_03594 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KEPPFGEB_03595 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
KEPPFGEB_03596 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KEPPFGEB_03597 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KEPPFGEB_03598 1.8e-72 rplO J binds to the 23S rRNA
KEPPFGEB_03599 1.9e-23 rpmD J Ribosomal protein L30
KEPPFGEB_03600 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KEPPFGEB_03601 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KEPPFGEB_03602 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KEPPFGEB_03603 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KEPPFGEB_03604 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KEPPFGEB_03605 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KEPPFGEB_03606 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KEPPFGEB_03607 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KEPPFGEB_03608 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KEPPFGEB_03609 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KEPPFGEB_03610 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KEPPFGEB_03611 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KEPPFGEB_03612 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KEPPFGEB_03613 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KEPPFGEB_03614 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KEPPFGEB_03615 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KEPPFGEB_03616 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
KEPPFGEB_03617 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KEPPFGEB_03618 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KEPPFGEB_03619 8.2e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
KEPPFGEB_03620 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KEPPFGEB_03621 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KEPPFGEB_03622 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KEPPFGEB_03623 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KEPPFGEB_03624 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
KEPPFGEB_03625 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEPPFGEB_03626 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEPPFGEB_03627 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
KEPPFGEB_03628 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KEPPFGEB_03629 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KEPPFGEB_03630 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KEPPFGEB_03631 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KEPPFGEB_03632 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
KEPPFGEB_03633 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KEPPFGEB_03634 4.4e-115 sigH K Belongs to the sigma-70 factor family
KEPPFGEB_03635 1.2e-88 yacP S RNA-binding protein containing a PIN domain
KEPPFGEB_03636 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KEPPFGEB_03637 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KEPPFGEB_03638 2.1e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KEPPFGEB_03639 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
KEPPFGEB_03640 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KEPPFGEB_03641 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KEPPFGEB_03642 5.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KEPPFGEB_03643 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KEPPFGEB_03644 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KEPPFGEB_03645 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KEPPFGEB_03646 0.0 clpC O Belongs to the ClpA ClpB family
KEPPFGEB_03647 1.1e-200 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KEPPFGEB_03648 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KEPPFGEB_03649 2.9e-76 ctsR K Belongs to the CtsR family
KEPPFGEB_03654 7.8e-08
KEPPFGEB_03662 2e-08
KEPPFGEB_03666 5e-142 spo0M S COG4326 Sporulation control protein
KEPPFGEB_03667 1.2e-26
KEPPFGEB_03668 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
KEPPFGEB_03669 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KEPPFGEB_03671 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KEPPFGEB_03672 3e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KEPPFGEB_03673 5.6e-170 ssuA M Sulfonate ABC transporter
KEPPFGEB_03674 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KEPPFGEB_03675 9e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KEPPFGEB_03677 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KEPPFGEB_03678 3.8e-76 ygaO
KEPPFGEB_03679 4.4e-29 K Transcriptional regulator
KEPPFGEB_03681 8.7e-113 yhzB S B3/4 domain
KEPPFGEB_03682 3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KEPPFGEB_03683 4.4e-177 yhbB S Putative amidase domain
KEPPFGEB_03684 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KEPPFGEB_03685 1.2e-109 yhbD K Protein of unknown function (DUF4004)
KEPPFGEB_03686 1e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
KEPPFGEB_03687 3e-69 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
KEPPFGEB_03688 0.0 prkA T Ser protein kinase
KEPPFGEB_03689 2.5e-225 yhbH S Belongs to the UPF0229 family
KEPPFGEB_03690 2.2e-76 yhbI K DNA-binding transcription factor activity
KEPPFGEB_03691 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
KEPPFGEB_03692 3.1e-271 yhcA EGP Major facilitator Superfamily
KEPPFGEB_03693 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
KEPPFGEB_03694 2.8e-37 yhcC
KEPPFGEB_03695 1.3e-54
KEPPFGEB_03696 1.9e-59 yhcF K Transcriptional regulator
KEPPFGEB_03697 4e-122 yhcG V ABC transporter, ATP-binding protein
KEPPFGEB_03698 7.7e-166 yhcH V ABC transporter, ATP-binding protein
KEPPFGEB_03699 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KEPPFGEB_03700 1e-30 cspB K Cold-shock protein
KEPPFGEB_03701 3.1e-150 metQ M Belongs to the nlpA lipoprotein family
KEPPFGEB_03702 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
KEPPFGEB_03703 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KEPPFGEB_03704 1.1e-40 yhcM
KEPPFGEB_03705 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KEPPFGEB_03706 2.5e-167 yhcP
KEPPFGEB_03707 5.2e-100 yhcQ M Spore coat protein
KEPPFGEB_03708 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
KEPPFGEB_03709 5.4e-104 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
KEPPFGEB_03710 3.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KEPPFGEB_03711 2.1e-67 yhcU S Family of unknown function (DUF5365)
KEPPFGEB_03712 9.9e-68 yhcV S COG0517 FOG CBS domain
KEPPFGEB_03713 4.6e-120 yhcW 5.4.2.6 S hydrolase
KEPPFGEB_03714 4.6e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KEPPFGEB_03715 6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KEPPFGEB_03716 1.2e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KEPPFGEB_03717 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KEPPFGEB_03718 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KEPPFGEB_03719 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KEPPFGEB_03720 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KEPPFGEB_03721 2.7e-213 yhcY 2.7.13.3 T Histidine kinase
KEPPFGEB_03722 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEPPFGEB_03723 3.6e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
KEPPFGEB_03724 1.2e-38 yhdB S YhdB-like protein
KEPPFGEB_03725 1.8e-53 yhdC S Protein of unknown function (DUF3889)
KEPPFGEB_03726 2.5e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KEPPFGEB_03727 1e-75 nsrR K Transcriptional regulator
KEPPFGEB_03728 3.1e-236 ygxB M Conserved TM helix
KEPPFGEB_03729 2.1e-276 ycgB S Stage V sporulation protein R
KEPPFGEB_03730 4.7e-252 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KEPPFGEB_03731 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KEPPFGEB_03732 3.8e-162 citR K Transcriptional regulator
KEPPFGEB_03733 6.5e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
KEPPFGEB_03734 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEPPFGEB_03735 3.4e-250 yhdG E amino acid
KEPPFGEB_03736 4.4e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KEPPFGEB_03737 1.5e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEPPFGEB_03738 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEPPFGEB_03739 8.1e-45 yhdK S Sigma-M inhibitor protein
KEPPFGEB_03740 6.6e-201 yhdL S Sigma factor regulator N-terminal
KEPPFGEB_03741 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
KEPPFGEB_03742 7.5e-191 yhdN C Aldo keto reductase
KEPPFGEB_03743 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KEPPFGEB_03744 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KEPPFGEB_03745 4.1e-74 cueR K transcriptional
KEPPFGEB_03746 8.8e-223 yhdR 2.6.1.1 E Aminotransferase
KEPPFGEB_03747 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
KEPPFGEB_03748 9.3e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KEPPFGEB_03749 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KEPPFGEB_03750 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KEPPFGEB_03752 2.7e-181 yhdY M Mechanosensitive ion channel
KEPPFGEB_03753 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KEPPFGEB_03754 4.8e-146 yheN G deacetylase
KEPPFGEB_03755 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KEPPFGEB_03756 2.6e-226 nhaC C Na H antiporter
KEPPFGEB_03757 1.5e-83 nhaX T Belongs to the universal stress protein A family
KEPPFGEB_03758 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KEPPFGEB_03759 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KEPPFGEB_03760 7.6e-109 yheG GM NAD(P)H-binding
KEPPFGEB_03761 6.3e-28 sspB S spore protein
KEPPFGEB_03762 1.3e-36 yheE S Family of unknown function (DUF5342)
KEPPFGEB_03763 3.3e-266 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KEPPFGEB_03764 6.9e-214 yheC HJ YheC/D like ATP-grasp
KEPPFGEB_03765 6.3e-202 yheB S Belongs to the UPF0754 family
KEPPFGEB_03766 9.5e-48 yheA S Belongs to the UPF0342 family
KEPPFGEB_03767 1.5e-205 yhaZ L DNA alkylation repair enzyme
KEPPFGEB_03768 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
KEPPFGEB_03769 3e-292 hemZ H coproporphyrinogen III oxidase
KEPPFGEB_03770 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
KEPPFGEB_03771 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
KEPPFGEB_03773 6.7e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
KEPPFGEB_03774 2.4e-26 S YhzD-like protein
KEPPFGEB_03775 5.7e-166 yhaQ S ABC transporter, ATP-binding protein
KEPPFGEB_03776 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KEPPFGEB_03777 7.5e-225 yhaO L DNA repair exonuclease
KEPPFGEB_03778 0.0 yhaN L AAA domain
KEPPFGEB_03779 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
KEPPFGEB_03780 1.6e-21 yhaL S Sporulation protein YhaL
KEPPFGEB_03781 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KEPPFGEB_03782 8.7e-90 yhaK S Putative zincin peptidase
KEPPFGEB_03783 1.3e-54 yhaI S Protein of unknown function (DUF1878)
KEPPFGEB_03784 1e-113 hpr K Negative regulator of protease production and sporulation
KEPPFGEB_03785 7e-39 yhaH S YtxH-like protein
KEPPFGEB_03786 3.6e-80 trpP S Tryptophan transporter TrpP
KEPPFGEB_03787 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KEPPFGEB_03788 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KEPPFGEB_03789 4.6e-137 ecsA V transporter (ATP-binding protein)
KEPPFGEB_03790 1.7e-213 ecsB U ABC transporter
KEPPFGEB_03791 6.9e-114 ecsC S EcsC protein family
KEPPFGEB_03792 2.8e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KEPPFGEB_03793 1.6e-231 yhfA C membrane
KEPPFGEB_03794 4.3e-31 1.15.1.2 C Rubrerythrin
KEPPFGEB_03795 7.1e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KEPPFGEB_03796 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KEPPFGEB_03797 2.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KEPPFGEB_03798 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KEPPFGEB_03799 5e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KEPPFGEB_03800 5.4e-101 yhgD K Transcriptional regulator
KEPPFGEB_03801 4.3e-229 yhgE S YhgE Pip N-terminal domain protein
KEPPFGEB_03802 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KEPPFGEB_03803 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
KEPPFGEB_03804 2.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
KEPPFGEB_03805 1.1e-71 3.4.13.21 S ASCH
KEPPFGEB_03806 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KEPPFGEB_03807 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KEPPFGEB_03808 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
KEPPFGEB_03809 8.5e-111 yhfK GM NmrA-like family
KEPPFGEB_03810 1e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KEPPFGEB_03811 1.3e-64 yhfM
KEPPFGEB_03812 5.9e-241 yhfN 3.4.24.84 O Peptidase M48
KEPPFGEB_03813 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
KEPPFGEB_03814 5e-78 VY92_01935 K acetyltransferase
KEPPFGEB_03815 5.4e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
KEPPFGEB_03816 4.3e-159 yfmC M Periplasmic binding protein
KEPPFGEB_03817 2.1e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KEPPFGEB_03818 6.5e-196 vraB 2.3.1.9 I Belongs to the thiolase family
KEPPFGEB_03819 9.6e-272 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KEPPFGEB_03820 8.5e-91 bioY S BioY family
KEPPFGEB_03821 3.5e-180 hemAT NT chemotaxis protein
KEPPFGEB_03822 4.4e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KEPPFGEB_03823 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEPPFGEB_03824 1.3e-32 yhzC S IDEAL
KEPPFGEB_03825 4.2e-109 comK K Competence transcription factor
KEPPFGEB_03826 1.4e-167 IQ Enoyl-(Acyl carrier protein) reductase
KEPPFGEB_03827 8.1e-39 yhjA S Excalibur calcium-binding domain
KEPPFGEB_03828 8.8e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEPPFGEB_03829 4.5e-26 yhjC S Protein of unknown function (DUF3311)
KEPPFGEB_03830 2.5e-59 yhjD
KEPPFGEB_03831 9.1e-110 yhjE S SNARE associated Golgi protein
KEPPFGEB_03832 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
KEPPFGEB_03833 2.1e-277 yhjG CH FAD binding domain
KEPPFGEB_03834 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
KEPPFGEB_03837 2.5e-212 glcP G Major Facilitator Superfamily
KEPPFGEB_03838 2.7e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
KEPPFGEB_03839 5.8e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
KEPPFGEB_03840 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
KEPPFGEB_03841 4.5e-188 yhjM 5.1.1.1 K Transcriptional regulator
KEPPFGEB_03842 4.2e-201 abrB S membrane
KEPPFGEB_03843 3.5e-211 EGP Transmembrane secretion effector
KEPPFGEB_03844 0.0 S Sugar transport-related sRNA regulator N-term
KEPPFGEB_03845 8.4e-78 yhjR S Rubrerythrin
KEPPFGEB_03846 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KEPPFGEB_03847 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KEPPFGEB_03848 1.8e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KEPPFGEB_03849 0.0 sbcC L COG0419 ATPase involved in DNA repair
KEPPFGEB_03850 1.1e-49 yisB V COG1403 Restriction endonuclease
KEPPFGEB_03851 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
KEPPFGEB_03852 5.3e-63 gerPE S Spore germination protein GerPE
KEPPFGEB_03853 3.1e-23 gerPD S Spore germination protein
KEPPFGEB_03854 5.3e-54 gerPC S Spore germination protein
KEPPFGEB_03855 4e-34 gerPB S cell differentiation
KEPPFGEB_03856 1.9e-33 gerPA S Spore germination protein
KEPPFGEB_03857 1.5e-22 yisI S Spo0E like sporulation regulatory protein
KEPPFGEB_03858 5.3e-175 cotH M Spore Coat
KEPPFGEB_03859 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KEPPFGEB_03860 3e-57 yisL S UPF0344 protein
KEPPFGEB_03861 0.0 wprA O Belongs to the peptidase S8 family
KEPPFGEB_03862 1.5e-100 yisN S Protein of unknown function (DUF2777)
KEPPFGEB_03863 0.0 asnO 6.3.5.4 E Asparagine synthase
KEPPFGEB_03864 1e-87 yizA S Damage-inducible protein DinB
KEPPFGEB_03865 2.9e-145 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
KEPPFGEB_03866 4e-243 yisQ V Mate efflux family protein
KEPPFGEB_03867 4.5e-160 yisR K Transcriptional regulator
KEPPFGEB_03868 2.4e-184 purR K helix_turn _helix lactose operon repressor
KEPPFGEB_03869 7e-192 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
KEPPFGEB_03870 7e-92 yisT S DinB family
KEPPFGEB_03871 6e-106 argO S Lysine exporter protein LysE YggA
KEPPFGEB_03872 1.1e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEPPFGEB_03873 7.5e-35 mcbG S Pentapeptide repeats (9 copies)
KEPPFGEB_03874 1.2e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KEPPFGEB_03875 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
KEPPFGEB_03876 1.9e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KEPPFGEB_03877 2.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KEPPFGEB_03878 7.6e-118 comB 3.1.3.71 H Belongs to the ComB family
KEPPFGEB_03879 1.6e-140 yitD 4.4.1.19 S synthase
KEPPFGEB_03880 1.6e-112 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KEPPFGEB_03881 3.5e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KEPPFGEB_03882 2.6e-228 yitG EGP Major facilitator Superfamily
KEPPFGEB_03883 8.7e-148 yitH K Acetyltransferase (GNAT) domain
KEPPFGEB_03884 3e-70 yjcF S Acetyltransferase (GNAT) domain
KEPPFGEB_03885 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KEPPFGEB_03886 4.3e-54 yajQ S Belongs to the UPF0234 family
KEPPFGEB_03887 3.4e-160 cvfB S protein conserved in bacteria
KEPPFGEB_03888 8.5e-94
KEPPFGEB_03889 2.6e-169
KEPPFGEB_03890 5.8e-97 S Sporulation delaying protein SdpA
KEPPFGEB_03891 1.5e-58 K Transcriptional regulator PadR-like family
KEPPFGEB_03892 2.5e-93
KEPPFGEB_03893 1.4e-44 yitR S Domain of unknown function (DUF3784)
KEPPFGEB_03894 1.2e-307 nprB 3.4.24.28 E Peptidase M4
KEPPFGEB_03895 2.5e-158 yitS S protein conserved in bacteria
KEPPFGEB_03896 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
KEPPFGEB_03897 5e-73 ipi S Intracellular proteinase inhibitor
KEPPFGEB_03898 1.2e-17 S Protein of unknown function (DUF3813)
KEPPFGEB_03900 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KEPPFGEB_03901 1.3e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KEPPFGEB_03902 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
KEPPFGEB_03903 1.5e-22 pilT S Proteolipid membrane potential modulator
KEPPFGEB_03904 6.4e-268 yitY C D-arabinono-1,4-lactone oxidase
KEPPFGEB_03905 1.7e-88 norB G Major Facilitator Superfamily
KEPPFGEB_03906 2.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KEPPFGEB_03907 2e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KEPPFGEB_03908 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KEPPFGEB_03909 3.2e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KEPPFGEB_03910 7.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KEPPFGEB_03911 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KEPPFGEB_03912 2.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KEPPFGEB_03913 9.5e-28 yjzC S YjzC-like protein
KEPPFGEB_03914 2.3e-16 yjzD S Protein of unknown function (DUF2929)
KEPPFGEB_03915 1.1e-141 yjaU I carboxylic ester hydrolase activity
KEPPFGEB_03916 5.3e-101 yjaV
KEPPFGEB_03917 2.5e-183 med S Transcriptional activator protein med
KEPPFGEB_03918 7.3e-26 comZ S ComZ
KEPPFGEB_03919 5e-21 yjzB
KEPPFGEB_03920 6.6e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KEPPFGEB_03921 5.2e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KEPPFGEB_03922 1.6e-148 yjaZ O Zn-dependent protease
KEPPFGEB_03923 1.8e-184 appD P Belongs to the ABC transporter superfamily
KEPPFGEB_03924 3.6e-185 appF E Belongs to the ABC transporter superfamily
KEPPFGEB_03925 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
KEPPFGEB_03926 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEPPFGEB_03927 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEPPFGEB_03928 5e-147 yjbA S Belongs to the UPF0736 family
KEPPFGEB_03929 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KEPPFGEB_03930 0.0 oppA E ABC transporter substrate-binding protein
KEPPFGEB_03931 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEPPFGEB_03932 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEPPFGEB_03933 6.8e-198 oppD P Belongs to the ABC transporter superfamily
KEPPFGEB_03934 5.5e-172 oppF E Belongs to the ABC transporter superfamily
KEPPFGEB_03935 5.3e-210 yjbB EGP Major Facilitator Superfamily
KEPPFGEB_03936 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEPPFGEB_03937 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KEPPFGEB_03938 6e-112 yjbE P Integral membrane protein TerC family
KEPPFGEB_03939 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KEPPFGEB_03940 3.1e-220 yjbF S Competence protein
KEPPFGEB_03941 0.0 pepF E oligoendopeptidase F
KEPPFGEB_03942 1.8e-20
KEPPFGEB_03943 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KEPPFGEB_03944 3.7e-72 yjbI S Bacterial-like globin
KEPPFGEB_03945 8.5e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KEPPFGEB_03946 4.6e-100 yjbK S protein conserved in bacteria
KEPPFGEB_03947 2.1e-61 yjbL S Belongs to the UPF0738 family
KEPPFGEB_03948 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
KEPPFGEB_03949 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KEPPFGEB_03950 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KEPPFGEB_03951 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KEPPFGEB_03952 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KEPPFGEB_03953 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KEPPFGEB_03954 1.6e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
KEPPFGEB_03955 1.4e-217 thiO 1.4.3.19 E Glycine oxidase
KEPPFGEB_03956 6.7e-30 thiS H thiamine diphosphate biosynthetic process
KEPPFGEB_03957 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KEPPFGEB_03958 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KEPPFGEB_03959 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KEPPFGEB_03960 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KEPPFGEB_03961 5.9e-54 yjbX S Spore coat protein
KEPPFGEB_03962 5.2e-83 cotZ S Spore coat protein
KEPPFGEB_03963 3.4e-96 cotY S Spore coat protein Z
KEPPFGEB_03964 6.4e-77 cotX S Spore Coat Protein X and V domain
KEPPFGEB_03965 8.5e-32 cotW
KEPPFGEB_03966 2.3e-55 cotV S Spore Coat Protein X and V domain
KEPPFGEB_03967 1.9e-56 yjcA S Protein of unknown function (DUF1360)
KEPPFGEB_03970 2.9e-38 spoVIF S Stage VI sporulation protein F
KEPPFGEB_03971 0.0 yjcD 3.6.4.12 L DNA helicase
KEPPFGEB_03972 1.7e-38
KEPPFGEB_03973 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEPPFGEB_03974 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KEPPFGEB_03975 6.5e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
KEPPFGEB_03976 6.5e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KEPPFGEB_03977 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KEPPFGEB_03978 5.9e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
KEPPFGEB_03979 1.1e-212 yjcL S Protein of unknown function (DUF819)
KEPPFGEB_03981 3.3e-30
KEPPFGEB_03982 2.1e-250 M nucleic acid phosphodiester bond hydrolysis
KEPPFGEB_03983 1.1e-13
KEPPFGEB_03987 4.7e-67 S response regulator aspartate phosphatase
KEPPFGEB_03988 5.4e-46 yjcS S Antibiotic biosynthesis monooxygenase
KEPPFGEB_03989 2e-140 IQ Enoyl-(Acyl carrier protein) reductase
KEPPFGEB_03991 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
KEPPFGEB_03992 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
KEPPFGEB_03993 1.3e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
KEPPFGEB_03994 1.6e-49 yjdF S Protein of unknown function (DUF2992)
KEPPFGEB_03995 1e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
KEPPFGEB_03997 5.2e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KEPPFGEB_03998 4.2e-29 S Domain of unknown function (DUF4177)
KEPPFGEB_03999 3.5e-52 yjdJ S Domain of unknown function (DUF4306)
KEPPFGEB_04000 5.2e-173 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KEPPFGEB_04002 9.3e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
KEPPFGEB_04003 1.2e-82 S Protein of unknown function (DUF2690)
KEPPFGEB_04004 2.3e-20 yjfB S Putative motility protein
KEPPFGEB_04005 1.5e-112 yjfC O Predicted Zn-dependent protease (DUF2268)
KEPPFGEB_04006 9e-33 yjfC O Predicted Zn-dependent protease (DUF2268)
KEPPFGEB_04007 2.7e-45 T PhoQ Sensor
KEPPFGEB_04008 2e-103 yjgB S Domain of unknown function (DUF4309)
KEPPFGEB_04009 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KEPPFGEB_04010 4.3e-95 yjgD S Protein of unknown function (DUF1641)
KEPPFGEB_04012 1.5e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
KEPPFGEB_04014 2.3e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
KEPPFGEB_04015 3.8e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KEPPFGEB_04016 1.4e-29
KEPPFGEB_04017 1e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KEPPFGEB_04018 5.6e-122 ybbM S transport system, permease component
KEPPFGEB_04019 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
KEPPFGEB_04020 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
KEPPFGEB_04021 3.4e-91 yjlB S Cupin domain
KEPPFGEB_04022 7.1e-66 yjlC S Protein of unknown function (DUF1641)
KEPPFGEB_04023 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
KEPPFGEB_04024 3.5e-279 uxaC 5.3.1.12 G glucuronate isomerase
KEPPFGEB_04025 2.7e-247 yjmB G symporter YjmB
KEPPFGEB_04026 1.3e-187 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KEPPFGEB_04027 1.9e-189 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
KEPPFGEB_04028 2.2e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
KEPPFGEB_04029 1.9e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KEPPFGEB_04030 8.3e-227 exuT G Sugar (and other) transporter
KEPPFGEB_04031 8.9e-184 exuR K transcriptional
KEPPFGEB_04032 4.9e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
KEPPFGEB_04033 1.7e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
KEPPFGEB_04034 7.4e-130 MA20_18170 S membrane transporter protein
KEPPFGEB_04035 2.3e-78 yjoA S DinB family
KEPPFGEB_04036 2.1e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
KEPPFGEB_04037 1e-212 S response regulator aspartate phosphatase
KEPPFGEB_04039 6.3e-41 S YCII-related domain
KEPPFGEB_04040 7.2e-167 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
KEPPFGEB_04041 6.1e-61 yjqA S Bacterial PH domain
KEPPFGEB_04042 3.3e-109 yjqB S Pfam:DUF867
KEPPFGEB_04043 4.4e-160 ydbD P Catalase
KEPPFGEB_04044 1e-110 xkdA E IrrE N-terminal-like domain
KEPPFGEB_04045 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
KEPPFGEB_04047 8.6e-156 xkdB K sequence-specific DNA binding
KEPPFGEB_04048 4.1e-118 xkdC L Bacterial dnaA protein
KEPPFGEB_04051 2.3e-09 yqaO S Phage-like element PBSX protein XtrA
KEPPFGEB_04052 6.3e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KEPPFGEB_04053 4.5e-138 xtmA L phage terminase small subunit
KEPPFGEB_04054 1.2e-252 xtmB S phage terminase, large subunit
KEPPFGEB_04055 1.6e-285 yqbA S portal protein
KEPPFGEB_04056 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
KEPPFGEB_04057 5.8e-169 xkdG S Phage capsid family
KEPPFGEB_04058 5.1e-63 yqbG S Protein of unknown function (DUF3199)
KEPPFGEB_04059 2.5e-64 yqbH S Domain of unknown function (DUF3599)
KEPPFGEB_04060 4.2e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
KEPPFGEB_04061 1.9e-77 xkdJ
KEPPFGEB_04062 3.6e-255 xkdK S Phage tail sheath C-terminal domain
KEPPFGEB_04063 6.1e-76 xkdM S Phage tail tube protein
KEPPFGEB_04064 2.3e-75 S Phage XkdN-like tail assembly chaperone protein, TAC

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)