ORF_ID e_value Gene_name EC_number CAZy COGs Description
NMBLNCOP_00006 8.9e-83 ydcK S Belongs to the SprT family
NMBLNCOP_00007 0.0 yhgF K COG2183 Transcriptional accessory protein
NMBLNCOP_00008 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NMBLNCOP_00009 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMBLNCOP_00010 7.8e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NMBLNCOP_00011 1.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
NMBLNCOP_00012 7.1e-189 rsbU 3.1.3.3 KT phosphatase
NMBLNCOP_00013 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NMBLNCOP_00014 5.2e-57 rsbS T antagonist
NMBLNCOP_00015 1.3e-143 rsbR T Positive regulator of sigma-B
NMBLNCOP_00016 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NMBLNCOP_00017 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NMBLNCOP_00018 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMBLNCOP_00019 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NMBLNCOP_00020 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NMBLNCOP_00021 1.2e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NMBLNCOP_00022 5.1e-260 ydbT S Membrane
NMBLNCOP_00023 2.1e-82 ydbS S Bacterial PH domain
NMBLNCOP_00024 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NMBLNCOP_00025 2.8e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NMBLNCOP_00026 1.1e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NMBLNCOP_00027 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NMBLNCOP_00028 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMBLNCOP_00029 2.2e-07 S Fur-regulated basic protein A
NMBLNCOP_00030 1.1e-18 S Fur-regulated basic protein B
NMBLNCOP_00031 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NMBLNCOP_00032 2.7e-52 ydbL
NMBLNCOP_00033 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NMBLNCOP_00034 1.3e-168 ydbJ V ABC transporter, ATP-binding protein
NMBLNCOP_00035 4.4e-181 ydbI S AI-2E family transporter
NMBLNCOP_00036 4.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMBLNCOP_00037 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
NMBLNCOP_00038 8.1e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NMBLNCOP_00039 9.6e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NMBLNCOP_00040 2.3e-153 ydbD P Catalase
NMBLNCOP_00041 2e-61 ydbC S Domain of unknown function (DUF4937
NMBLNCOP_00042 2.6e-58 ydbB G Cupin domain
NMBLNCOP_00044 1.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NMBLNCOP_00045 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NMBLNCOP_00047 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NMBLNCOP_00048 9.4e-40
NMBLNCOP_00049 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NMBLNCOP_00050 1.1e-75 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NMBLNCOP_00051 0.0 ydaO E amino acid
NMBLNCOP_00052 0.0 ydaN S Bacterial cellulose synthase subunit
NMBLNCOP_00053 4.5e-233 ydaM M Glycosyl transferase family group 2
NMBLNCOP_00054 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NMBLNCOP_00055 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
NMBLNCOP_00056 4.8e-207 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NMBLNCOP_00057 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMBLNCOP_00058 2.5e-74 lrpC K Transcriptional regulator
NMBLNCOP_00059 3.6e-45 ydzA EGP Major facilitator Superfamily
NMBLNCOP_00060 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NMBLNCOP_00061 6.8e-77 ydaG 1.4.3.5 S general stress protein
NMBLNCOP_00062 5.6e-103 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMBLNCOP_00063 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NMBLNCOP_00064 3.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMBLNCOP_00065 1.7e-97 ydaC Q Methyltransferase domain
NMBLNCOP_00066 2.1e-293 ydaB IQ acyl-CoA ligase
NMBLNCOP_00067 0.0 mtlR K transcriptional regulator, MtlR
NMBLNCOP_00068 8.1e-176 ydhF S Oxidoreductase
NMBLNCOP_00069 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NMBLNCOP_00070 8e-47 yczJ S biosynthesis
NMBLNCOP_00072 3.5e-117 ycsK E anatomical structure formation involved in morphogenesis
NMBLNCOP_00073 1.7e-131 kipR K Transcriptional regulator
NMBLNCOP_00074 2.5e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NMBLNCOP_00075 3.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NMBLNCOP_00076 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
NMBLNCOP_00077 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NMBLNCOP_00078 8.8e-139 ycsF S Belongs to the UPF0271 (lamB) family
NMBLNCOP_00079 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NMBLNCOP_00081 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NMBLNCOP_00082 6.3e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NMBLNCOP_00083 1.7e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NMBLNCOP_00084 2.1e-09 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NMBLNCOP_00085 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NMBLNCOP_00086 9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NMBLNCOP_00087 5.7e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NMBLNCOP_00088 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NMBLNCOP_00089 2.6e-53
NMBLNCOP_00090 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NMBLNCOP_00091 3.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
NMBLNCOP_00092 1.4e-99 ycnI S protein conserved in bacteria
NMBLNCOP_00093 4.6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMBLNCOP_00094 1.8e-148 glcU U Glucose uptake
NMBLNCOP_00095 3.8e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMBLNCOP_00096 1.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMBLNCOP_00097 6.2e-271 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMBLNCOP_00098 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NMBLNCOP_00099 1.6e-45 ycnE S Monooxygenase
NMBLNCOP_00100 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NMBLNCOP_00101 6.5e-154 ycnC K Transcriptional regulator
NMBLNCOP_00102 1.2e-250 ycnB EGP Major facilitator Superfamily
NMBLNCOP_00103 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NMBLNCOP_00104 8.9e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NMBLNCOP_00105 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMBLNCOP_00106 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMBLNCOP_00107 5.2e-251 lysC 2.7.2.4 E Belongs to the aspartokinase family
NMBLNCOP_00110 1.6e-80 S aspartate phosphatase
NMBLNCOP_00111 1.1e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NMBLNCOP_00112 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMBLNCOP_00113 3.7e-194 yclI V ABC transporter (permease) YclI
NMBLNCOP_00114 1.6e-120 yclH P ABC transporter
NMBLNCOP_00115 1.9e-195 gerKB F Spore germination protein
NMBLNCOP_00116 1.6e-230 gerKC S spore germination
NMBLNCOP_00117 2.7e-278 gerKA EG Spore germination protein
NMBLNCOP_00119 1.1e-298 yclG M Pectate lyase superfamily protein
NMBLNCOP_00120 8.1e-266 dtpT E amino acid peptide transporter
NMBLNCOP_00121 5.4e-158 yclE 3.4.11.5 S Alpha beta hydrolase
NMBLNCOP_00122 5e-81 yclD
NMBLNCOP_00123 4e-39 bsdD 4.1.1.61 S response to toxic substance
NMBLNCOP_00124 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NMBLNCOP_00125 7.6e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NMBLNCOP_00126 1.2e-160 bsdA K LysR substrate binding domain
NMBLNCOP_00127 1.1e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NMBLNCOP_00128 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NMBLNCOP_00129 1.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NMBLNCOP_00130 9.7e-115 yczE S membrane
NMBLNCOP_00131 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NMBLNCOP_00132 1.2e-120 ycxD K GntR family transcriptional regulator
NMBLNCOP_00133 1.7e-111 ycxD K GntR family transcriptional regulator
NMBLNCOP_00134 1.1e-159 ycxC EG EamA-like transporter family
NMBLNCOP_00135 3.3e-87 S YcxB-like protein
NMBLNCOP_00136 4.1e-223 EGP Major Facilitator Superfamily
NMBLNCOP_00137 5.7e-140 srfAD Q thioesterase
NMBLNCOP_00138 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NMBLNCOP_00139 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMBLNCOP_00140 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMBLNCOP_00141 1.3e-63 hxlR K transcriptional
NMBLNCOP_00142 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NMBLNCOP_00143 3.9e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NMBLNCOP_00144 2.2e-80 tlpC 2.7.13.3 NT chemotaxis protein
NMBLNCOP_00145 1.8e-93 tlpC 2.7.13.3 NT chemotaxis protein
NMBLNCOP_00146 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
NMBLNCOP_00147 1.1e-68 nin S Competence protein J (ComJ)
NMBLNCOP_00148 2e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMBLNCOP_00149 3.5e-52 yckD S Protein of unknown function (DUF2680)
NMBLNCOP_00150 3.1e-75 yckC S membrane
NMBLNCOP_00152 1.7e-130 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NMBLNCOP_00153 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
NMBLNCOP_00154 1.2e-224 yciC S GTPases (G3E family)
NMBLNCOP_00155 9.4e-101 yciB M ErfK YbiS YcfS YnhG
NMBLNCOP_00156 4.3e-169 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NMBLNCOP_00157 2.9e-221 nasA P COG2223 Nitrate nitrite transporter
NMBLNCOP_00158 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NMBLNCOP_00159 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMBLNCOP_00160 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NMBLNCOP_00161 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NMBLNCOP_00162 1.6e-271 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NMBLNCOP_00163 2.4e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NMBLNCOP_00164 8.5e-159 I alpha/beta hydrolase fold
NMBLNCOP_00165 1.2e-139 ycgR S permeases
NMBLNCOP_00166 2.2e-146 ycgQ S membrane
NMBLNCOP_00167 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NMBLNCOP_00168 3.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMBLNCOP_00169 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NMBLNCOP_00170 5.1e-170 ycgM E Proline dehydrogenase
NMBLNCOP_00171 2.4e-144 ycgL S Predicted nucleotidyltransferase
NMBLNCOP_00172 5.2e-181 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NMBLNCOP_00173 9.3e-178 oxyR3 K LysR substrate binding domain
NMBLNCOP_00174 4.9e-142 yafE Q ubiE/COQ5 methyltransferase family
NMBLNCOP_00175 1.5e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NMBLNCOP_00177 3.1e-107 tmrB S AAA domain
NMBLNCOP_00178 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NMBLNCOP_00179 2.4e-112 ycgI S Domain of unknown function (DUF1989)
NMBLNCOP_00180 1.8e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NMBLNCOP_00181 2.9e-150 yqcI S YqcI/YcgG family
NMBLNCOP_00182 6.8e-113 ycgF E Lysine exporter protein LysE YggA
NMBLNCOP_00183 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
NMBLNCOP_00184 3.9e-263 mdr EGP Major facilitator Superfamily
NMBLNCOP_00185 6.5e-293 lctP C L-lactate permease
NMBLNCOP_00186 7.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NMBLNCOP_00187 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NMBLNCOP_00188 4.1e-81 ycgB
NMBLNCOP_00189 2.4e-139 ycgA S Membrane
NMBLNCOP_00190 3.4e-80 ycgA S Membrane
NMBLNCOP_00191 5.4e-217 amhX S amidohydrolase
NMBLNCOP_00192 5.3e-164 opuAC E glycine betaine
NMBLNCOP_00193 1.3e-127 opuAB P glycine betaine
NMBLNCOP_00194 4.3e-228 proV 3.6.3.32 E glycine betaine
NMBLNCOP_00195 3e-44 K helix_turn_helix, Arsenical Resistance Operon Repressor
NMBLNCOP_00196 5.3e-204 yceJ EGP Uncharacterised MFS-type transporter YbfB
NMBLNCOP_00197 1.1e-217 naiP P Uncharacterised MFS-type transporter YbfB
NMBLNCOP_00198 2e-192 yceH P Belongs to the TelA family
NMBLNCOP_00199 0.0 yceG S Putative component of 'biosynthetic module'
NMBLNCOP_00200 6.3e-137 terC P Protein of unknown function (DUF475)
NMBLNCOP_00201 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
NMBLNCOP_00202 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NMBLNCOP_00203 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NMBLNCOP_00204 2.6e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMBLNCOP_00205 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NMBLNCOP_00206 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NMBLNCOP_00207 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
NMBLNCOP_00208 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NMBLNCOP_00209 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
NMBLNCOP_00210 2.7e-173 S response regulator aspartate phosphatase
NMBLNCOP_00211 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
NMBLNCOP_00212 5.3e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NMBLNCOP_00213 2e-269 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NMBLNCOP_00214 6.6e-177 ycdA S Domain of unknown function (DUF5105)
NMBLNCOP_00215 1.5e-172 yccK C Aldo keto reductase
NMBLNCOP_00216 3.5e-200 natB CP ABC-2 family transporter protein
NMBLNCOP_00217 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NMBLNCOP_00218 1.2e-126 lytR_2 T LytTr DNA-binding domain
NMBLNCOP_00219 2.3e-157 2.7.13.3 T GHKL domain
NMBLNCOP_00220 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
NMBLNCOP_00221 1.4e-41 S RDD family
NMBLNCOP_00222 1.2e-101 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NMBLNCOP_00223 3.4e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NMBLNCOP_00224 5.9e-100 yxaF K Transcriptional regulator
NMBLNCOP_00225 7.6e-229 lmrB EGP the major facilitator superfamily
NMBLNCOP_00226 9.9e-200 ycbU E Selenocysteine lyase
NMBLNCOP_00227 1.7e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NMBLNCOP_00228 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NMBLNCOP_00229 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NMBLNCOP_00230 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NMBLNCOP_00231 8.1e-134 ycbR T vWA found in TerF C terminus
NMBLNCOP_00232 1.3e-78 sleB 3.5.1.28 M Cell wall
NMBLNCOP_00233 1.8e-52 ycbP S Protein of unknown function (DUF2512)
NMBLNCOP_00234 5.1e-114 S ABC-2 family transporter protein
NMBLNCOP_00235 1.7e-165 ycbN V ABC transporter, ATP-binding protein
NMBLNCOP_00236 9.2e-167 T PhoQ Sensor
NMBLNCOP_00237 1.9e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMBLNCOP_00238 2.6e-169 eamA1 EG spore germination
NMBLNCOP_00239 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NMBLNCOP_00240 3.5e-174 ycbJ S Macrolide 2'-phosphotransferase
NMBLNCOP_00241 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
NMBLNCOP_00242 4.7e-123 ycbG K FCD
NMBLNCOP_00243 2.7e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NMBLNCOP_00244 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NMBLNCOP_00245 2e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMBLNCOP_00246 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NMBLNCOP_00247 9e-170 glnL T Regulator
NMBLNCOP_00248 3.6e-228 phoQ 2.7.13.3 T Histidine kinase
NMBLNCOP_00249 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
NMBLNCOP_00250 4.8e-255 agcS E Sodium alanine symporter
NMBLNCOP_00251 3.3e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NMBLNCOP_00252 3.7e-260 mmuP E amino acid
NMBLNCOP_00253 5.5e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NMBLNCOP_00255 4.9e-128 K UTRA
NMBLNCOP_00256 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NMBLNCOP_00257 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMBLNCOP_00258 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMBLNCOP_00259 3.9e-192 yceA S Belongs to the UPF0176 family
NMBLNCOP_00260 3.6e-249 S Erythromycin esterase
NMBLNCOP_00261 4.6e-45 ybfN
NMBLNCOP_00262 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NMBLNCOP_00263 2.7e-85 ybfM S SNARE associated Golgi protein
NMBLNCOP_00264 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NMBLNCOP_00265 1.8e-164 S Alpha/beta hydrolase family
NMBLNCOP_00267 4.5e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NMBLNCOP_00268 8.9e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NMBLNCOP_00269 5.7e-144 msmR K AraC-like ligand binding domain
NMBLNCOP_00270 4.4e-161 ybfH EG EamA-like transporter family
NMBLNCOP_00271 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
NMBLNCOP_00273 1.6e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
NMBLNCOP_00274 7.4e-169 ybfA 3.4.15.5 K FR47-like protein
NMBLNCOP_00275 1.5e-34 S Protein of unknown function (DUF2651)
NMBLNCOP_00276 7.3e-258 glpT G -transporter
NMBLNCOP_00277 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NMBLNCOP_00278 3e-290 ybeC E amino acid
NMBLNCOP_00279 4.9e-41 ybyB
NMBLNCOP_00280 3.5e-246 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NMBLNCOP_00281 7.5e-149 ybxI 3.5.2.6 V beta-lactamase
NMBLNCOP_00282 4.9e-30 ybxH S Family of unknown function (DUF5370)
NMBLNCOP_00283 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
NMBLNCOP_00284 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NMBLNCOP_00285 5.7e-214 ybdO S Domain of unknown function (DUF4885)
NMBLNCOP_00286 6.5e-151 ybdN
NMBLNCOP_00287 4.4e-138 KLT Protein tyrosine kinase
NMBLNCOP_00289 1e-171 T His Kinase A (phospho-acceptor) domain
NMBLNCOP_00290 1.3e-122 T Transcriptional regulatory protein, C terminal
NMBLNCOP_00291 8.4e-179 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMBLNCOP_00292 9.6e-79 txn CO Thioredoxin-like
NMBLNCOP_00293 7.8e-91 C HEAT repeats
NMBLNCOP_00294 4.7e-247 skfF S ABC transporter
NMBLNCOP_00295 6.7e-133 skfE V ABC transporter
NMBLNCOP_00296 1.7e-276 V CAAX protease self-immunity
NMBLNCOP_00297 9.1e-239 J 4Fe-4S single cluster domain
NMBLNCOP_00299 6.5e-202 ybcL EGP Major facilitator Superfamily
NMBLNCOP_00300 1.5e-49 ybzH K Helix-turn-helix domain
NMBLNCOP_00301 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
NMBLNCOP_00302 1.9e-46
NMBLNCOP_00304 3.6e-91 can 4.2.1.1 P carbonic anhydrase
NMBLNCOP_00305 0.0 ybcC S Belongs to the UPF0753 family
NMBLNCOP_00306 2.4e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NMBLNCOP_00307 4.8e-99 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NMBLNCOP_00308 2.9e-119 adaA 3.2.2.21 K Transcriptional regulator
NMBLNCOP_00309 9e-175 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NMBLNCOP_00311 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NMBLNCOP_00312 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NMBLNCOP_00313 3e-225 ybbR S protein conserved in bacteria
NMBLNCOP_00314 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMBLNCOP_00315 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NMBLNCOP_00316 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NMBLNCOP_00322 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NMBLNCOP_00323 1.9e-86 ybbJ J acetyltransferase
NMBLNCOP_00324 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NMBLNCOP_00325 1.4e-150 ybbH K transcriptional
NMBLNCOP_00326 8.3e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMBLNCOP_00327 1.6e-252 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NMBLNCOP_00328 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NMBLNCOP_00329 3.9e-237 ybbC 3.2.1.52 S protein conserved in bacteria
NMBLNCOP_00330 2.1e-304 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NMBLNCOP_00331 8e-166 feuA P Iron-uptake system-binding protein
NMBLNCOP_00332 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMBLNCOP_00333 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMBLNCOP_00334 3.8e-139 ybbA S Putative esterase
NMBLNCOP_00335 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
NMBLNCOP_00336 1.8e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NMBLNCOP_00338 9.6e-180 yaaC S YaaC-like Protein
NMBLNCOP_00339 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NMBLNCOP_00340 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NMBLNCOP_00341 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NMBLNCOP_00342 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NMBLNCOP_00343 1.2e-204 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NMBLNCOP_00344 1.3e-09
NMBLNCOP_00345 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NMBLNCOP_00346 2.3e-113 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NMBLNCOP_00347 1.2e-212 yaaH M Glycoside Hydrolase Family
NMBLNCOP_00348 1.9e-95 yaaI Q COG1335 Amidases related to nicotinamidase
NMBLNCOP_00349 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NMBLNCOP_00350 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMBLNCOP_00351 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NMBLNCOP_00352 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NMBLNCOP_00353 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NMBLNCOP_00354 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NMBLNCOP_00355 2.7e-64 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMBLNCOP_00357 2.3e-111 lytR K Transcriptional regulator
NMBLNCOP_00358 2.7e-25 M Glycosyl transferases group 1
NMBLNCOP_00359 1.7e-132 tagG GM Transport permease protein
NMBLNCOP_00360 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
NMBLNCOP_00361 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NMBLNCOP_00362 1.2e-84 gerD
NMBLNCOP_00363 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NMBLNCOP_00364 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMBLNCOP_00365 1.8e-64 ybaK S Protein of unknown function (DUF2521)
NMBLNCOP_00366 7.6e-143 ybaJ Q Methyltransferase domain
NMBLNCOP_00367 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NMBLNCOP_00368 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NMBLNCOP_00369 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NMBLNCOP_00370 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMBLNCOP_00371 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMBLNCOP_00372 2.1e-154 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMBLNCOP_00373 3.6e-58 rplQ J Ribosomal protein L17
NMBLNCOP_00374 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMBLNCOP_00375 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NMBLNCOP_00376 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NMBLNCOP_00377 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NMBLNCOP_00378 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NMBLNCOP_00379 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NMBLNCOP_00380 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NMBLNCOP_00381 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NMBLNCOP_00382 1.8e-72 rplO J binds to the 23S rRNA
NMBLNCOP_00383 1.9e-23 rpmD J Ribosomal protein L30
NMBLNCOP_00384 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NMBLNCOP_00385 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NMBLNCOP_00386 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NMBLNCOP_00387 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NMBLNCOP_00388 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMBLNCOP_00389 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NMBLNCOP_00390 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NMBLNCOP_00391 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NMBLNCOP_00392 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NMBLNCOP_00393 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NMBLNCOP_00394 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NMBLNCOP_00395 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NMBLNCOP_00396 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NMBLNCOP_00397 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NMBLNCOP_00398 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NMBLNCOP_00399 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NMBLNCOP_00400 3e-105 rplD J Forms part of the polypeptide exit tunnel
NMBLNCOP_00401 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NMBLNCOP_00402 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NMBLNCOP_00403 4.5e-185 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NMBLNCOP_00404 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NMBLNCOP_00405 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NMBLNCOP_00406 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NMBLNCOP_00407 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NMBLNCOP_00408 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NMBLNCOP_00409 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMBLNCOP_00410 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMBLNCOP_00411 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
NMBLNCOP_00412 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NMBLNCOP_00413 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NMBLNCOP_00414 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NMBLNCOP_00415 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NMBLNCOP_00416 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NMBLNCOP_00417 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NMBLNCOP_00418 4.4e-115 sigH K Belongs to the sigma-70 factor family
NMBLNCOP_00419 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NMBLNCOP_00420 3.4e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMBLNCOP_00421 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NMBLNCOP_00422 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMBLNCOP_00423 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
NMBLNCOP_00424 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NMBLNCOP_00425 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NMBLNCOP_00426 5.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NMBLNCOP_00427 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NMBLNCOP_00428 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NMBLNCOP_00429 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NMBLNCOP_00430 0.0 clpC O Belongs to the ClpA ClpB family
NMBLNCOP_00431 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NMBLNCOP_00432 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NMBLNCOP_00433 2.9e-76 ctsR K Belongs to the CtsR family
NMBLNCOP_00434 1.1e-16 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMBLNCOP_00438 3.9e-156 ydhU P Catalase
NMBLNCOP_00439 2.9e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NMBLNCOP_00440 7.4e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
NMBLNCOP_00441 4e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NMBLNCOP_00442 1.1e-132 ydhQ K UTRA
NMBLNCOP_00443 9e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMBLNCOP_00444 3.4e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMBLNCOP_00445 5.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NMBLNCOP_00446 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NMBLNCOP_00447 1.3e-199 pbuE EGP Major facilitator Superfamily
NMBLNCOP_00448 2.5e-98 ydhK M Protein of unknown function (DUF1541)
NMBLNCOP_00449 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NMBLNCOP_00450 4.1e-86 K Acetyltransferase (GNAT) domain
NMBLNCOP_00452 4.6e-69 frataxin S Domain of unknown function (DU1801)
NMBLNCOP_00453 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NMBLNCOP_00454 1.9e-127
NMBLNCOP_00455 2e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NMBLNCOP_00456 3.3e-244 ydhD M Glycosyl hydrolase
NMBLNCOP_00457 6.5e-122 ydhC K FCD
NMBLNCOP_00458 3.5e-121 ydhB S membrane transporter protein
NMBLNCOP_00459 7.4e-209 tcaB EGP Major facilitator Superfamily
NMBLNCOP_00460 2.4e-69 ydgJ K Winged helix DNA-binding domain
NMBLNCOP_00461 1e-113 drgA C nitroreductase
NMBLNCOP_00462 0.0 ydgH S drug exporters of the RND superfamily
NMBLNCOP_00463 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
NMBLNCOP_00464 1.4e-88 dinB S DinB family
NMBLNCOP_00465 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NMBLNCOP_00466 1.6e-302 expZ S ABC transporter
NMBLNCOP_00467 1.8e-102 G Xylose isomerase-like TIM barrel
NMBLNCOP_00468 1e-190 csbC EGP Major facilitator Superfamily
NMBLNCOP_00469 3.5e-119 purR K helix_turn _helix lactose operon repressor
NMBLNCOP_00470 3.3e-133 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NMBLNCOP_00471 2.6e-47 FG HIT domain
NMBLNCOP_00472 7.9e-82 yycN 2.3.1.128 K Acetyltransferase
NMBLNCOP_00473 8.1e-52 S DoxX-like family
NMBLNCOP_00474 1.1e-93 K Bacterial regulatory proteins, tetR family
NMBLNCOP_00475 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
NMBLNCOP_00476 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
NMBLNCOP_00477 8.5e-75 cotP O Belongs to the small heat shock protein (HSP20) family
NMBLNCOP_00478 5.2e-122 ydfS S Protein of unknown function (DUF421)
NMBLNCOP_00479 4.4e-118 ydfR S Protein of unknown function (DUF421)
NMBLNCOP_00481 2.4e-28
NMBLNCOP_00482 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NMBLNCOP_00483 4.8e-57 traF CO Thioredoxin
NMBLNCOP_00484 8.8e-63 mhqP S DoxX
NMBLNCOP_00485 4e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NMBLNCOP_00486 9.6e-112 ydfN C nitroreductase
NMBLNCOP_00487 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMBLNCOP_00488 9.2e-147 K Bacterial transcription activator, effector binding domain
NMBLNCOP_00489 8.5e-117 S Protein of unknown function (DUF554)
NMBLNCOP_00490 2.6e-174 S Alpha/beta hydrolase family
NMBLNCOP_00491 0.0 ydfJ S drug exporters of the RND superfamily
NMBLNCOP_00492 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMBLNCOP_00493 6.7e-175 ydfH 2.7.13.3 T Histidine kinase
NMBLNCOP_00495 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NMBLNCOP_00496 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NMBLNCOP_00497 4.2e-115 ydfE S Flavin reductase like domain
NMBLNCOP_00498 8.7e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMBLNCOP_00499 6.3e-160 ydfC EG EamA-like transporter family
NMBLNCOP_00500 1.4e-147 ydfB J GNAT acetyltransferase
NMBLNCOP_00501 2.8e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NMBLNCOP_00502 6.3e-57 arsR K transcriptional
NMBLNCOP_00503 2.1e-103 ydeS K Transcriptional regulator
NMBLNCOP_00504 3.3e-193 ydeR EGP Major facilitator Superfamily
NMBLNCOP_00505 8.6e-110 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
NMBLNCOP_00506 4.8e-69 ydeP K Transcriptional regulator
NMBLNCOP_00507 3.9e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NMBLNCOP_00508 5.2e-56 K HxlR-like helix-turn-helix
NMBLNCOP_00509 6.7e-102 ydeN S Serine hydrolase
NMBLNCOP_00510 6e-73 maoC I N-terminal half of MaoC dehydratase
NMBLNCOP_00511 6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMBLNCOP_00512 1.8e-153 ydeK EG -transporter
NMBLNCOP_00513 2.3e-85 K Transcriptional regulator C-terminal region
NMBLNCOP_00514 1.8e-14 ptsH G PTS HPr component phosphorylation site
NMBLNCOP_00515 1.1e-31 S SNARE associated Golgi protein
NMBLNCOP_00516 3.5e-88
NMBLNCOP_00517 2.1e-103 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NMBLNCOP_00518 2.7e-45 ydeH
NMBLNCOP_00519 1.2e-217 ydeG EGP Major facilitator superfamily
NMBLNCOP_00520 6.2e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMBLNCOP_00521 9.9e-163 ydeE K AraC family transcriptional regulator
NMBLNCOP_00522 8.3e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NMBLNCOP_00523 9.9e-163 rhaS5 K AraC-like ligand binding domain
NMBLNCOP_00524 1.2e-139 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NMBLNCOP_00525 1.2e-77 carD K Transcription factor
NMBLNCOP_00526 8.7e-30 cspL K Cold shock
NMBLNCOP_00527 3.1e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NMBLNCOP_00528 9.6e-40
NMBLNCOP_00529 5.6e-34 K Helix-turn-helix XRE-family like proteins
NMBLNCOP_00530 4.5e-100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NMBLNCOP_00531 1.1e-35 S Putative lumazine-binding
NMBLNCOP_00532 1.3e-166 namA C NADPH dehydrogenase
NMBLNCOP_00533 4.2e-34 K helix_turn_helix multiple antibiotic resistance protein
NMBLNCOP_00534 9.2e-81 ylbE GM Nucleoside-diphosphate-sugar epimerases
NMBLNCOP_00535 4.4e-106 yfcA S membrane transporter protein
NMBLNCOP_00537 8.4e-26 S response regulator aspartate phosphatase
NMBLNCOP_00538 5.3e-29 S response regulator aspartate phosphatase
NMBLNCOP_00539 8.5e-67
NMBLNCOP_00542 3.6e-36 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NMBLNCOP_00543 3.8e-35 S Oxidoreductase family, C-terminal alpha/beta domain
NMBLNCOP_00546 2e-08
NMBLNCOP_00553 1.3e-09
NMBLNCOP_00554 7.8e-08
NMBLNCOP_00563 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NMBLNCOP_00564 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NMBLNCOP_00565 2.2e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NMBLNCOP_00566 1.1e-286 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NMBLNCOP_00567 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NMBLNCOP_00568 9.9e-77 tspO T membrane
NMBLNCOP_00569 9.7e-205 cotI S Spore coat protein
NMBLNCOP_00570 1.5e-216 cotSA M Glycosyl transferases group 1
NMBLNCOP_00571 6.3e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
NMBLNCOP_00573 3.3e-233 ytcC M Glycosyltransferase Family 4
NMBLNCOP_00574 9.1e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NMBLNCOP_00575 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMBLNCOP_00576 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
NMBLNCOP_00577 4.4e-132 dksA T COG1734 DnaK suppressor protein
NMBLNCOP_00578 4.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
NMBLNCOP_00579 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NMBLNCOP_00580 1.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NMBLNCOP_00581 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NMBLNCOP_00582 2.4e-270 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NMBLNCOP_00583 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NMBLNCOP_00584 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
NMBLNCOP_00585 7.3e-138 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NMBLNCOP_00586 6.7e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NMBLNCOP_00587 2.2e-149 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NMBLNCOP_00588 1.1e-24 S Domain of Unknown Function (DUF1540)
NMBLNCOP_00589 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NMBLNCOP_00590 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
NMBLNCOP_00591 6.1e-41 rpmE2 J Ribosomal protein L31
NMBLNCOP_00592 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NMBLNCOP_00593 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NMBLNCOP_00594 2.2e-70 ytkA S YtkA-like
NMBLNCOP_00596 2.1e-76 dps P Belongs to the Dps family
NMBLNCOP_00597 7.8e-62 ytkC S Bacteriophage holin family
NMBLNCOP_00598 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NMBLNCOP_00599 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NMBLNCOP_00600 1.4e-144 ytlC P ABC transporter
NMBLNCOP_00601 8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NMBLNCOP_00602 6.7e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NMBLNCOP_00603 1.2e-38 ytmB S Protein of unknown function (DUF2584)
NMBLNCOP_00604 4.8e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NMBLNCOP_00605 7.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NMBLNCOP_00606 0.0 asnB 6.3.5.4 E Asparagine synthase
NMBLNCOP_00607 2.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NMBLNCOP_00608 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NMBLNCOP_00609 4.2e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
NMBLNCOP_00610 2.8e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NMBLNCOP_00611 3.3e-106 ytqB J Putative rRNA methylase
NMBLNCOP_00612 8.1e-190 yhcC S Fe-S oxidoreductase
NMBLNCOP_00613 6.7e-41 ytzC S Protein of unknown function (DUF2524)
NMBLNCOP_00615 5.1e-66 ytrA K GntR family transcriptional regulator
NMBLNCOP_00616 7.1e-161 ytrB P abc transporter atp-binding protein
NMBLNCOP_00617 7.8e-148 P ABC-2 family transporter protein
NMBLNCOP_00618 1.1e-143
NMBLNCOP_00619 7.7e-126 ytrE V ABC transporter, ATP-binding protein
NMBLNCOP_00620 1.4e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NMBLNCOP_00621 1.7e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMBLNCOP_00622 6.2e-185 T PhoQ Sensor
NMBLNCOP_00623 1.1e-138 bceA V ABC transporter, ATP-binding protein
NMBLNCOP_00624 0.0 bceB V ABC transporter (permease)
NMBLNCOP_00625 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
NMBLNCOP_00626 5.1e-210 yttB EGP Major facilitator Superfamily
NMBLNCOP_00627 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NMBLNCOP_00628 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NMBLNCOP_00629 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMBLNCOP_00630 2.1e-51 ytwF P Sulfurtransferase
NMBLNCOP_00631 6.4e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NMBLNCOP_00632 4.4e-144 amyC P ABC transporter (permease)
NMBLNCOP_00633 1.5e-166 amyD P ABC transporter
NMBLNCOP_00634 9.8e-244 msmE G Bacterial extracellular solute-binding protein
NMBLNCOP_00635 1.4e-187 msmR K Transcriptional regulator
NMBLNCOP_00636 2.4e-172 ytaP S Acetyl xylan esterase (AXE1)
NMBLNCOP_00637 1.5e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NMBLNCOP_00638 1.7e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NMBLNCOP_00639 3.8e-210 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NMBLNCOP_00640 3.8e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NMBLNCOP_00641 1.2e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NMBLNCOP_00642 1.2e-219 bioI 1.14.14.46 C Cytochrome P450
NMBLNCOP_00643 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NMBLNCOP_00644 2.3e-151 ytcP G COG0395 ABC-type sugar transport system, permease component
NMBLNCOP_00645 3.4e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NMBLNCOP_00646 0.0 ytdP K Transcriptional regulator
NMBLNCOP_00647 9.9e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NMBLNCOP_00648 3e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NMBLNCOP_00649 4.6e-73 yteS G transport
NMBLNCOP_00650 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NMBLNCOP_00651 4.8e-117 yteU S Integral membrane protein
NMBLNCOP_00652 3.1e-26 yteV S Sporulation protein Cse60
NMBLNCOP_00653 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NMBLNCOP_00654 1.2e-230 ytfP S HI0933-like protein
NMBLNCOP_00655 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMBLNCOP_00656 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NMBLNCOP_00657 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NMBLNCOP_00658 1.8e-130 ythP V ABC transporter
NMBLNCOP_00659 1.1e-204 ythQ U Bacterial ABC transporter protein EcsB
NMBLNCOP_00660 1.8e-224 pbuO S permease
NMBLNCOP_00661 2.3e-270 pepV 3.5.1.18 E Dipeptidase
NMBLNCOP_00662 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NMBLNCOP_00663 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NMBLNCOP_00664 1.3e-165 ytlQ
NMBLNCOP_00665 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NMBLNCOP_00666 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NMBLNCOP_00667 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
NMBLNCOP_00668 2e-45 ytzH S YtzH-like protein
NMBLNCOP_00669 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NMBLNCOP_00670 2.4e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NMBLNCOP_00671 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NMBLNCOP_00672 2.2e-51 ytzB S small secreted protein
NMBLNCOP_00673 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NMBLNCOP_00674 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NMBLNCOP_00675 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NMBLNCOP_00676 9.8e-149 ytpQ S Belongs to the UPF0354 family
NMBLNCOP_00677 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMBLNCOP_00678 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NMBLNCOP_00679 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NMBLNCOP_00680 8e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NMBLNCOP_00681 6.6e-17 ytxH S COG4980 Gas vesicle protein
NMBLNCOP_00682 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
NMBLNCOP_00683 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NMBLNCOP_00684 3.8e-182 ccpA K catabolite control protein A
NMBLNCOP_00685 2.1e-146 motA N flagellar motor
NMBLNCOP_00686 1.4e-125 motS N Flagellar motor protein
NMBLNCOP_00687 6.1e-224 acuC BQ histone deacetylase
NMBLNCOP_00688 7.9e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
NMBLNCOP_00689 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NMBLNCOP_00690 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NMBLNCOP_00691 1.5e-236 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NMBLNCOP_00693 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NMBLNCOP_00694 1.7e-310 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NMBLNCOP_00695 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NMBLNCOP_00696 1e-108 yttP K Transcriptional regulator
NMBLNCOP_00697 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NMBLNCOP_00698 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NMBLNCOP_00699 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
NMBLNCOP_00700 1.6e-208 iscS2 2.8.1.7 E Cysteine desulfurase
NMBLNCOP_00701 1.3e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMBLNCOP_00702 2e-29 sspB S spore protein
NMBLNCOP_00703 2.3e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NMBLNCOP_00704 0.0 ytcJ S amidohydrolase
NMBLNCOP_00705 1.4e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMBLNCOP_00706 3e-179 sppA OU signal peptide peptidase SppA
NMBLNCOP_00707 8.5e-87 yteJ S RDD family
NMBLNCOP_00708 5.6e-116 ytfI S Protein of unknown function (DUF2953)
NMBLNCOP_00709 8.7e-70 ytfJ S Sporulation protein YtfJ
NMBLNCOP_00710 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NMBLNCOP_00711 2.7e-164 ytxK 2.1.1.72 L DNA methylase
NMBLNCOP_00712 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NMBLNCOP_00713 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NMBLNCOP_00714 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NMBLNCOP_00715 1.2e-266 argH 4.3.2.1 E argininosuccinate lyase
NMBLNCOP_00717 9.3e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMBLNCOP_00718 1.7e-130 ytkL S Belongs to the UPF0173 family
NMBLNCOP_00719 1.9e-172 ytlI K LysR substrate binding domain
NMBLNCOP_00720 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
NMBLNCOP_00721 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
NMBLNCOP_00722 2.1e-143 tcyK M Bacterial periplasmic substrate-binding proteins
NMBLNCOP_00723 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
NMBLNCOP_00724 1.9e-119 tcyM U Binding-protein-dependent transport system inner membrane component
NMBLNCOP_00725 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NMBLNCOP_00726 6.4e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMBLNCOP_00727 1.4e-46 ytnI O COG0695 Glutaredoxin and related proteins
NMBLNCOP_00728 3.7e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMBLNCOP_00729 1.7e-125 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
NMBLNCOP_00730 6.2e-235 ytnL 3.5.1.47 E hydrolase activity
NMBLNCOP_00731 2.7e-155 ytnM S membrane transporter protein
NMBLNCOP_00732 8e-241 ytoI K transcriptional regulator containing CBS domains
NMBLNCOP_00733 2.4e-47 ytpI S YtpI-like protein
NMBLNCOP_00734 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NMBLNCOP_00735 9.2e-29
NMBLNCOP_00736 8.2e-69 ytrI
NMBLNCOP_00737 3.2e-56 ytrH S Sporulation protein YtrH
NMBLNCOP_00738 0.0 dnaE 2.7.7.7 L DNA polymerase
NMBLNCOP_00739 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NMBLNCOP_00740 2.4e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NMBLNCOP_00741 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NMBLNCOP_00742 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NMBLNCOP_00743 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NMBLNCOP_00744 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NMBLNCOP_00745 3.4e-192 ytvI S sporulation integral membrane protein YtvI
NMBLNCOP_00746 4.7e-71 yeaL S membrane
NMBLNCOP_00747 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NMBLNCOP_00748 4.1e-242 icd 1.1.1.42 C isocitrate
NMBLNCOP_00749 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NMBLNCOP_00750 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMBLNCOP_00751 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NMBLNCOP_00752 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NMBLNCOP_00753 1.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NMBLNCOP_00754 2.8e-106 ytaF P Probably functions as a manganese efflux pump
NMBLNCOP_00755 4.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NMBLNCOP_00756 8.9e-161 ytbE S reductase
NMBLNCOP_00757 2.4e-204 ytbD EGP Major facilitator Superfamily
NMBLNCOP_00758 9.9e-67 ytcD K Transcriptional regulator
NMBLNCOP_00759 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NMBLNCOP_00760 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NMBLNCOP_00761 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NMBLNCOP_00762 4.5e-266 dnaB L Membrane attachment protein
NMBLNCOP_00763 1.1e-172 dnaI L Primosomal protein DnaI
NMBLNCOP_00764 2.3e-108 ytxB S SNARE associated Golgi protein
NMBLNCOP_00765 5.4e-158 ytxC S YtxC-like family
NMBLNCOP_00767 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMBLNCOP_00768 7.3e-149 ysaA S HAD-hyrolase-like
NMBLNCOP_00769 0.0 lytS 2.7.13.3 T Histidine kinase
NMBLNCOP_00770 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
NMBLNCOP_00771 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NMBLNCOP_00772 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NMBLNCOP_00774 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NMBLNCOP_00775 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NMBLNCOP_00776 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NMBLNCOP_00777 7.5e-45 ysdA S Membrane
NMBLNCOP_00778 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NMBLNCOP_00779 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
NMBLNCOP_00780 8.9e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NMBLNCOP_00781 7.8e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NMBLNCOP_00782 7.8e-310 araB 2.7.1.16 C Belongs to the ribulokinase family
NMBLNCOP_00783 3.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NMBLNCOP_00784 5.6e-144 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NMBLNCOP_00785 2.4e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NMBLNCOP_00786 4.9e-251 araN G carbohydrate transport
NMBLNCOP_00787 1.4e-167 araP G carbohydrate transport
NMBLNCOP_00788 3.8e-143 araQ G transport system permease
NMBLNCOP_00789 2.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NMBLNCOP_00790 0.0 cstA T Carbon starvation protein
NMBLNCOP_00791 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
NMBLNCOP_00792 1.1e-256 glcF C Glycolate oxidase
NMBLNCOP_00793 5.3e-259 glcD 1.1.3.15 C Glycolate oxidase subunit
NMBLNCOP_00794 1.8e-206 ysfB KT regulator
NMBLNCOP_00795 2.6e-32 sspI S Belongs to the SspI family
NMBLNCOP_00796 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMBLNCOP_00797 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NMBLNCOP_00798 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMBLNCOP_00799 9e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMBLNCOP_00800 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NMBLNCOP_00801 1.7e-85 cvpA S membrane protein, required for colicin V production
NMBLNCOP_00802 0.0 polX L COG1796 DNA polymerase IV (family X)
NMBLNCOP_00803 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NMBLNCOP_00804 7.3e-68 yshE S membrane
NMBLNCOP_00805 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NMBLNCOP_00806 4e-99 fadR K Transcriptional regulator
NMBLNCOP_00807 3.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NMBLNCOP_00808 6.5e-134 etfB C Electron transfer flavoprotein
NMBLNCOP_00809 1.8e-176 etfA C Electron transfer flavoprotein
NMBLNCOP_00811 2.9e-300 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NMBLNCOP_00812 2e-52 trxA O Belongs to the thioredoxin family
NMBLNCOP_00813 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NMBLNCOP_00814 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NMBLNCOP_00815 1.2e-79 yslB S Protein of unknown function (DUF2507)
NMBLNCOP_00816 2.4e-107 sdhC C succinate dehydrogenase
NMBLNCOP_00817 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NMBLNCOP_00818 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NMBLNCOP_00819 9.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NMBLNCOP_00820 1.2e-17 gerE K Transcriptional regulator
NMBLNCOP_00821 1.2e-48 yqaB E IrrE N-terminal-like domain
NMBLNCOP_00822 8.5e-20
NMBLNCOP_00823 9.4e-25 K sequence-specific DNA binding
NMBLNCOP_00824 3.2e-13 K Helix-turn-helix XRE-family like proteins
NMBLNCOP_00826 4.1e-45 S DNA binding
NMBLNCOP_00827 8.6e-83
NMBLNCOP_00832 5.8e-97
NMBLNCOP_00833 3.4e-69 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
NMBLNCOP_00834 6.9e-34 3.1.3.16 L DnaD domain protein
NMBLNCOP_00835 5.5e-120 xkdC L IstB-like ATP binding protein
NMBLNCOP_00836 2e-21 S YopX protein
NMBLNCOP_00837 1.7e-07
NMBLNCOP_00838 4e-54 S Protein of unknown function (DUF1064)
NMBLNCOP_00840 1.7e-25 yqaO S Phage-like element PBSX protein XtrA
NMBLNCOP_00844 1.2e-65
NMBLNCOP_00846 4.4e-46 S dUTPase
NMBLNCOP_00851 2e-70 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NMBLNCOP_00853 8.9e-17 K Transcriptional regulator
NMBLNCOP_00857 2.8e-81 yqaS L DNA packaging
NMBLNCOP_00858 2e-185 ps334 S Terminase-like family
NMBLNCOP_00859 8.2e-159 S Phage portal protein, SPP1 Gp6-like
NMBLNCOP_00861 1.6e-63 S Domain of unknown function (DUF4355)
NMBLNCOP_00862 1.9e-111 S Phage capsid family
NMBLNCOP_00864 1.4e-31 S Phage Mu protein F like protein
NMBLNCOP_00865 8.3e-17 S Phage gp6-like head-tail connector protein
NMBLNCOP_00866 3.6e-48
NMBLNCOP_00867 6.9e-23
NMBLNCOP_00868 1.2e-29
NMBLNCOP_00869 9.4e-104 Z012_02110 S Protein of unknown function (DUF3383)
NMBLNCOP_00870 3e-34
NMBLNCOP_00871 2.1e-16
NMBLNCOP_00872 3.7e-123 N phage tail tape measure protein
NMBLNCOP_00873 3e-40 3.5.1.28 M LysM domain
NMBLNCOP_00874 4.1e-30
NMBLNCOP_00875 1e-88
NMBLNCOP_00876 2.7e-23
NMBLNCOP_00877 4.8e-23 S Protein of unknown function (DUF2634)
NMBLNCOP_00878 3e-106 Z012_12235 S homolog of phage Mu protein gp47
NMBLNCOP_00879 7.8e-61
NMBLNCOP_00880 6.9e-45 S Domain of unknown function (DUF2479)
NMBLNCOP_00882 1e-14 xkdX
NMBLNCOP_00883 1.1e-27 xhlA S Haemolysin XhlA
NMBLNCOP_00884 2.7e-31 xhlB S SPP1 phage holin
NMBLNCOP_00885 4.7e-106 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NMBLNCOP_00887 3.2e-59
NMBLNCOP_00888 9.3e-45 S YolD-like protein
NMBLNCOP_00889 1e-167 L Recombinase
NMBLNCOP_00890 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NMBLNCOP_00891 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NMBLNCOP_00892 2.9e-196 gerM S COG5401 Spore germination protein
NMBLNCOP_00893 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NMBLNCOP_00894 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NMBLNCOP_00895 4.1e-92 ysnB S Phosphoesterase
NMBLNCOP_00897 5.5e-131 ysnF S protein conserved in bacteria
NMBLNCOP_00898 1.7e-134 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NMBLNCOP_00899 1.1e-77 ysnE K acetyltransferase
NMBLNCOP_00900 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NMBLNCOP_00901 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
NMBLNCOP_00902 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NMBLNCOP_00903 9.3e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NMBLNCOP_00904 1.8e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NMBLNCOP_00905 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMBLNCOP_00906 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMBLNCOP_00907 2.3e-187 ysoA H Tetratricopeptide repeat
NMBLNCOP_00908 2.4e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NMBLNCOP_00909 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NMBLNCOP_00910 1.1e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NMBLNCOP_00911 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NMBLNCOP_00912 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NMBLNCOP_00913 1.4e-89 ysxD
NMBLNCOP_00914 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NMBLNCOP_00915 3.6e-146 hemX O cytochrome C
NMBLNCOP_00916 5.7e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NMBLNCOP_00917 9.3e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NMBLNCOP_00918 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
NMBLNCOP_00919 5.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NMBLNCOP_00920 1.5e-210 spoVID M stage VI sporulation protein D
NMBLNCOP_00921 7.8e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NMBLNCOP_00922 1.6e-25
NMBLNCOP_00923 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NMBLNCOP_00924 2.8e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NMBLNCOP_00925 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NMBLNCOP_00926 7.3e-162 spoIIB S Sporulation related domain
NMBLNCOP_00927 8.3e-102 maf D septum formation protein Maf
NMBLNCOP_00928 9.8e-68 radC E Belongs to the UPF0758 family
NMBLNCOP_00929 1.6e-226 S Recombinase
NMBLNCOP_00930 4.5e-71 S Pfam:Peptidase_M78
NMBLNCOP_00931 3.4e-63 S sequence-specific DNA binding
NMBLNCOP_00932 8.8e-09 plcR K helix-turn-helix
NMBLNCOP_00935 3.5e-21 S Uncharacterized protein YqaH
NMBLNCOP_00937 2e-92 S DNA protection
NMBLNCOP_00938 1.5e-164 tadZ D AAA domain
NMBLNCOP_00940 2.6e-71 S Protein of unknown function (DUF669)
NMBLNCOP_00941 0.0 S hydrolase activity
NMBLNCOP_00942 6.2e-65
NMBLNCOP_00943 7.9e-94 S nuclease activity
NMBLNCOP_00944 1.2e-80
NMBLNCOP_00946 1.2e-16 S YopX protein
NMBLNCOP_00948 1.5e-59
NMBLNCOP_00952 6.2e-50 V HNH endonuclease
NMBLNCOP_00953 1.8e-79 L phage terminase small subunit
NMBLNCOP_00954 1.5e-303 S Terminase
NMBLNCOP_00955 1.4e-12
NMBLNCOP_00956 7.4e-175 S Phage portal protein
NMBLNCOP_00957 6.8e-81 S peptidase activity
NMBLNCOP_00958 4.6e-156 gp36 S capsid protein
NMBLNCOP_00959 3.8e-20
NMBLNCOP_00960 1.4e-39 S Phage gp6-like head-tail connector protein
NMBLNCOP_00961 6.1e-38 S Phage head-tail joining protein
NMBLNCOP_00962 1.4e-50 S Bacteriophage HK97-gp10, putative tail-component
NMBLNCOP_00964 1.2e-77 S Phage tail tube protein
NMBLNCOP_00967 0.0 D phage tail tape measure protein
NMBLNCOP_00968 5.8e-112 S Phage tail protein
NMBLNCOP_00969 1.4e-221 NU Prophage endopeptidase tail
NMBLNCOP_00970 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
NMBLNCOP_00971 2.7e-88
NMBLNCOP_00972 1e-12
NMBLNCOP_00974 1.7e-95 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
NMBLNCOP_00975 6e-57 S Pfam:Phage_holin_4_1
NMBLNCOP_00976 6.8e-128 xlyB 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NMBLNCOP_00977 4.8e-52 S SMI1-KNR4 cell-wall
NMBLNCOP_00978 4.8e-281 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMBLNCOP_00979 1.5e-12
NMBLNCOP_00985 1e-26 K Helix-turn-helix domain
NMBLNCOP_00988 5.4e-51 radC E Belongs to the UPF0758 family
NMBLNCOP_00989 1.8e-184 mreB D Rod shape-determining protein MreB
NMBLNCOP_00990 1.1e-156 mreC M Involved in formation and maintenance of cell shape
NMBLNCOP_00991 1.4e-84 mreD M shape-determining protein
NMBLNCOP_00992 3.5e-107 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NMBLNCOP_00993 2.5e-144 minD D Belongs to the ParA family
NMBLNCOP_00994 4.2e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NMBLNCOP_00995 5.9e-160 spoIVFB S Stage IV sporulation protein
NMBLNCOP_00996 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NMBLNCOP_00997 4.1e-56 ysxB J ribosomal protein
NMBLNCOP_00998 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NMBLNCOP_00999 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NMBLNCOP_01000 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NMBLNCOP_01001 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NMBLNCOP_01002 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
NMBLNCOP_01003 7.9e-94 niaR S small molecule binding protein (contains 3H domain)
NMBLNCOP_01004 2e-227 nifS 2.8.1.7 E Cysteine desulfurase
NMBLNCOP_01005 1.5e-297 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NMBLNCOP_01006 7.3e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NMBLNCOP_01007 4.5e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NMBLNCOP_01008 1.7e-157 safA M spore coat assembly protein SafA
NMBLNCOP_01009 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMBLNCOP_01010 3.6e-126 yebC K transcriptional regulatory protein
NMBLNCOP_01011 1.9e-259 alsT E Sodium alanine symporter
NMBLNCOP_01012 1.3e-18 S Family of unknown function (DUF5412)
NMBLNCOP_01014 2.1e-117 yrzF T serine threonine protein kinase
NMBLNCOP_01015 1.7e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NMBLNCOP_01016 5.3e-253 csbX EGP Major facilitator Superfamily
NMBLNCOP_01017 4.8e-93 bofC S BofC C-terminal domain
NMBLNCOP_01018 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NMBLNCOP_01019 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NMBLNCOP_01020 2.6e-18 yrzS S Protein of unknown function (DUF2905)
NMBLNCOP_01021 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NMBLNCOP_01022 4.4e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NMBLNCOP_01023 1.1e-38 yajC U Preprotein translocase subunit YajC
NMBLNCOP_01024 1.1e-72 yrzE S Protein of unknown function (DUF3792)
NMBLNCOP_01025 1e-111 yrbG S membrane
NMBLNCOP_01026 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMBLNCOP_01027 3.6e-48 yrzD S Post-transcriptional regulator
NMBLNCOP_01028 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NMBLNCOP_01029 2.3e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NMBLNCOP_01030 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NMBLNCOP_01031 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NMBLNCOP_01032 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NMBLNCOP_01033 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NMBLNCOP_01034 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NMBLNCOP_01035 3.3e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
NMBLNCOP_01037 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NMBLNCOP_01038 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NMBLNCOP_01039 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NMBLNCOP_01040 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NMBLNCOP_01041 1.2e-70 cymR K Transcriptional regulator
NMBLNCOP_01042 1.8e-212 iscS 2.8.1.7 E Cysteine desulfurase
NMBLNCOP_01043 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NMBLNCOP_01044 1.4e-15 S COG0457 FOG TPR repeat
NMBLNCOP_01045 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NMBLNCOP_01046 7.8e-82 yrrD S protein conserved in bacteria
NMBLNCOP_01047 9.8e-31 yrzR
NMBLNCOP_01048 8e-08 S Protein of unknown function (DUF3918)
NMBLNCOP_01049 7.6e-107 glnP P ABC transporter
NMBLNCOP_01050 1.8e-108 gluC P ABC transporter
NMBLNCOP_01051 2.4e-142 glnH ET Belongs to the bacterial solute-binding protein 3 family
NMBLNCOP_01052 1.2e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NMBLNCOP_01053 2.7e-170 yrrI S AI-2E family transporter
NMBLNCOP_01054 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NMBLNCOP_01055 1.7e-41 yrzL S Belongs to the UPF0297 family
NMBLNCOP_01056 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NMBLNCOP_01057 1.2e-45 yrzB S Belongs to the UPF0473 family
NMBLNCOP_01058 3.7e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NMBLNCOP_01059 8.6e-119 yrrM 2.1.1.104 S O-methyltransferase
NMBLNCOP_01060 1.6e-171 yegQ O Peptidase U32
NMBLNCOP_01061 2.7e-246 yegQ O COG0826 Collagenase and related proteases
NMBLNCOP_01062 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NMBLNCOP_01063 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NMBLNCOP_01064 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NMBLNCOP_01065 4.2e-63 yrrS S Protein of unknown function (DUF1510)
NMBLNCOP_01066 1e-25 yrzA S Protein of unknown function (DUF2536)
NMBLNCOP_01067 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NMBLNCOP_01068 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NMBLNCOP_01069 2.6e-169 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NMBLNCOP_01070 1.8e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NMBLNCOP_01071 4.6e-35 yrhC S YrhC-like protein
NMBLNCOP_01072 5.4e-78 yrhD S Protein of unknown function (DUF1641)
NMBLNCOP_01073 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NMBLNCOP_01074 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
NMBLNCOP_01075 1.8e-142 focA P Formate nitrite
NMBLNCOP_01078 1.8e-93 yrhH Q methyltransferase
NMBLNCOP_01079 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NMBLNCOP_01080 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NMBLNCOP_01081 9.1e-44 yrhK S YrhK-like protein
NMBLNCOP_01082 0.0 yrhL I Acyltransferase family
NMBLNCOP_01083 1.6e-149 rsiV S Protein of unknown function (DUF3298)
NMBLNCOP_01084 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NMBLNCOP_01085 7e-150 yrhO K Archaeal transcriptional regulator TrmB
NMBLNCOP_01086 1.1e-105 yrhP E LysE type translocator
NMBLNCOP_01087 1.3e-252 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NMBLNCOP_01088 0.0 levR K PTS system fructose IIA component
NMBLNCOP_01089 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
NMBLNCOP_01090 8.2e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NMBLNCOP_01091 9.9e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NMBLNCOP_01092 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NMBLNCOP_01093 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NMBLNCOP_01094 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
NMBLNCOP_01095 6.7e-198 adhA 1.1.1.1 C alcohol dehydrogenase
NMBLNCOP_01096 4.3e-47 yraB K helix_turn_helix, mercury resistance
NMBLNCOP_01097 2.8e-48 yraD M Spore coat protein
NMBLNCOP_01098 7.5e-26 yraE
NMBLNCOP_01099 3.3e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NMBLNCOP_01100 6.4e-63 yraF M Spore coat protein
NMBLNCOP_01101 1.5e-36 yraG
NMBLNCOP_01102 3.8e-66 E Glyoxalase-like domain
NMBLNCOP_01103 5.4e-61 T sh3 domain protein
NMBLNCOP_01104 4.9e-60 T sh3 domain protein
NMBLNCOP_01106 1.7e-148 S Alpha beta hydrolase
NMBLNCOP_01107 1.9e-40 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMBLNCOP_01108 3.2e-155 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NMBLNCOP_01109 1.6e-185 yrpG C Aldo/keto reductase family
NMBLNCOP_01110 1.2e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NMBLNCOP_01111 1e-115 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NMBLNCOP_01112 2.9e-26 epsA I Passenger-associated-transport-repeat
NMBLNCOP_01113 2.4e-48 yjbR S YjbR
NMBLNCOP_01114 3.3e-80 bmrR K helix_turn_helix, mercury resistance
NMBLNCOP_01115 2.7e-24 bmrR K helix_turn_helix, mercury resistance
NMBLNCOP_01116 6.8e-96 flr S Flavin reductase like domain
NMBLNCOP_01117 3.6e-123 yrpD S Domain of unknown function, YrpD
NMBLNCOP_01118 3.8e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NMBLNCOP_01119 1.4e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NMBLNCOP_01120 1.9e-166 aadK G Streptomycin adenylyltransferase
NMBLNCOP_01121 6.4e-90 yrdA S DinB family
NMBLNCOP_01123 1.8e-55 S Protein of unknown function (DUF2568)
NMBLNCOP_01124 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
NMBLNCOP_01125 5.5e-74 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
NMBLNCOP_01126 4.6e-148 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
NMBLNCOP_01127 4.4e-251 cscA 3.2.1.26 GH32 G invertase
NMBLNCOP_01128 2.1e-198 rafB P LacY proton/sugar symporter
NMBLNCOP_01129 1.5e-139 msmG P PFAM binding-protein-dependent transport systems inner membrane component
NMBLNCOP_01130 1.8e-149 msmF P Binding-protein-dependent transport system inner membrane component
NMBLNCOP_01131 7.7e-228 msmE G Bacterial extracellular solute-binding protein
NMBLNCOP_01132 1.4e-162 scrR K transcriptional
NMBLNCOP_01133 3e-64 K Transcriptional regulator
NMBLNCOP_01135 5.4e-12 K Acetyltransferase (GNAT) family
NMBLNCOP_01136 3e-221 cypA C Cytochrome P450
NMBLNCOP_01138 6.3e-79 bkdR K helix_turn_helix ASNC type
NMBLNCOP_01139 6.2e-137 azlC E AzlC protein
NMBLNCOP_01140 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NMBLNCOP_01141 4.6e-228 brnQ E Component of the transport system for branched-chain amino acids
NMBLNCOP_01142 2.1e-37 C COG2041 Sulfite oxidase and related enzymes
NMBLNCOP_01143 4.2e-161 gltR K LysR substrate binding domain
NMBLNCOP_01144 6.5e-66 yodA S tautomerase
NMBLNCOP_01145 2.8e-142 czcD P COG1230 Co Zn Cd efflux system component
NMBLNCOP_01146 7.8e-146 trkA P Oxidoreductase
NMBLNCOP_01147 8.6e-159 yrdQ K Transcriptional regulator
NMBLNCOP_01148 1.7e-171 yrdR EG EamA-like transporter family
NMBLNCOP_01149 3.9e-16 S YrzO-like protein
NMBLNCOP_01150 7.2e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NMBLNCOP_01151 4.5e-82 bltD 2.3.1.57 K FR47-like protein
NMBLNCOP_01152 1e-210 blt EGP Major facilitator Superfamily
NMBLNCOP_01153 3.2e-147 bltR K helix_turn_helix, mercury resistance
NMBLNCOP_01155 1.3e-107 yrkC G Cupin domain
NMBLNCOP_01156 7.8e-39 yrkD S protein conserved in bacteria
NMBLNCOP_01157 4.7e-82 yrkE O DsrE/DsrF/DrsH-like family
NMBLNCOP_01158 1.4e-46 P Rhodanese Homology Domain
NMBLNCOP_01159 4.6e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
NMBLNCOP_01160 2.7e-205 yrkH P Rhodanese Homology Domain
NMBLNCOP_01161 1.6e-35 yrkI O Belongs to the sulfur carrier protein TusA family
NMBLNCOP_01162 8.8e-102 yrkJ S membrane transporter protein
NMBLNCOP_01163 1.9e-111 K COG1802 Transcriptional regulators
NMBLNCOP_01164 1.7e-179 yjlA EG Putative multidrug resistance efflux transporter
NMBLNCOP_01166 8.2e-79 S Protein of unknown function with HXXEE motif
NMBLNCOP_01167 1.5e-97 ywrO S Flavodoxin-like fold
NMBLNCOP_01168 6.3e-21 cisA2 L Recombinase
NMBLNCOP_01169 1.8e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMBLNCOP_01170 4.1e-44 yqaB E IrrE N-terminal-like domain
NMBLNCOP_01172 2e-97 adk 2.7.4.3 F adenylate kinase activity
NMBLNCOP_01174 1.1e-32 K sequence-specific DNA binding
NMBLNCOP_01175 5.9e-17 K Helix-turn-helix XRE-family like proteins
NMBLNCOP_01177 4.9e-102
NMBLNCOP_01181 9.5e-175 yqaJ L YqaJ-like viral recombinase domain
NMBLNCOP_01182 1.7e-135 recT L RecT family
NMBLNCOP_01183 4.4e-121 3.1.3.16 L DnaD domain protein
NMBLNCOP_01184 4.4e-163 xkdC L IstB-like ATP binding protein
NMBLNCOP_01186 2.6e-68 rusA L Endodeoxyribonuclease RusA
NMBLNCOP_01187 8.9e-30 yqaO S Phage-like element PBSX protein XtrA
NMBLNCOP_01189 1.1e-48 wecC 1.1.1.336 M ArpU family transcriptional regulator
NMBLNCOP_01193 2.8e-89 yrdC 3.5.1.19 Q Isochorismatase family
NMBLNCOP_01195 8.3e-99 yqaS L DNA packaging
NMBLNCOP_01196 1.4e-248 S phage terminase, large subunit
NMBLNCOP_01197 2.5e-286 yqbA S portal protein
NMBLNCOP_01198 1.3e-149 S Phage Mu protein F like protein
NMBLNCOP_01200 1.4e-112 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NMBLNCOP_01201 1.9e-167 xkdG S Phage capsid family
NMBLNCOP_01202 1.2e-46 S YqbF, hypothetical protein domain
NMBLNCOP_01203 2.7e-67 S Protein of unknown function (DUF3199)
NMBLNCOP_01204 1.7e-63 yqbH S Domain of unknown function (DUF3599)
NMBLNCOP_01205 5.3e-84 S Bacteriophage HK97-gp10, putative tail-component
NMBLNCOP_01206 5.1e-75
NMBLNCOP_01207 1e-24
NMBLNCOP_01208 2.2e-252 xkdK S Phage tail sheath C-terminal domain
NMBLNCOP_01209 2.3e-75 xkdM S Phage tail tube protein
NMBLNCOP_01210 6.2e-68 S Phage XkdN-like tail assembly chaperone protein, TAC
NMBLNCOP_01211 0.0 xkdO L Transglycosylase SLT domain
NMBLNCOP_01212 2.2e-112 xkdP S Lysin motif
NMBLNCOP_01213 2.2e-42 qacC U Small Multidrug Resistance protein
NMBLNCOP_01214 1.2e-177 yqbQ 3.2.1.96 G NLP P60 protein
NMBLNCOP_01215 9.4e-32 xkdR S Protein of unknown function (DUF2577)
NMBLNCOP_01216 1.3e-70 xkdS S Protein of unknown function (DUF2634)
NMBLNCOP_01217 1.2e-186 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NMBLNCOP_01218 7.4e-98 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NMBLNCOP_01219 1e-36
NMBLNCOP_01220 2.3e-164
NMBLNCOP_01221 7.3e-42 xkdW S XkdW protein
NMBLNCOP_01222 1.3e-18
NMBLNCOP_01223 3e-159 xepA
NMBLNCOP_01224 2.2e-67 S Bacteriophage holin family
NMBLNCOP_01225 1.3e-129 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NMBLNCOP_01226 3e-117 EGP Necrosis inducing protein (NPP1)
NMBLNCOP_01227 7.8e-82 S SMI1-KNR4 cell-wall
NMBLNCOP_01228 4.3e-298 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMBLNCOP_01230 5e-66 S response regulator aspartate phosphatase
NMBLNCOP_01232 3.5e-100 yrkC G Cupin domain
NMBLNCOP_01233 5.1e-21
NMBLNCOP_01234 1.6e-36 yrkD S protein conserved in bacteria
NMBLNCOP_01235 3.4e-80 yrkE O DsrE/DsrF/DrsH-like family
NMBLNCOP_01236 8.4e-55 P Rhodanese Homology Domain
NMBLNCOP_01237 5.6e-87 yrkF OP Belongs to the sulfur carrier protein TusA family
NMBLNCOP_01238 1.9e-57 perX S DsrE/DsrF-like family
NMBLNCOP_01239 4.5e-200 yrkH P Rhodanese Homology Domain
NMBLNCOP_01240 9.5e-33 yrkI O Belongs to the sulfur carrier protein TusA family
NMBLNCOP_01241 1.2e-111 yrkJ S membrane transporter protein
NMBLNCOP_01242 8.4e-149 yhjR 2.7.7.87 S Rubrerythrin
NMBLNCOP_01243 1.4e-112 ydfS S Protein of unknown function (DUF421)
NMBLNCOP_01246 3.5e-277 cisA2 L Recombinase
NMBLNCOP_01247 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMBLNCOP_01248 2.4e-74 nucB M Deoxyribonuclease NucA/NucB
NMBLNCOP_01249 6.3e-131 yqeB
NMBLNCOP_01250 1e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NMBLNCOP_01251 1.8e-105 yqeD S SNARE associated Golgi protein
NMBLNCOP_01252 1.8e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMBLNCOP_01253 4e-141 yqeF E GDSL-like Lipase/Acylhydrolase
NMBLNCOP_01255 5.3e-95 yqeG S hydrolase of the HAD superfamily
NMBLNCOP_01256 3.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NMBLNCOP_01257 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NMBLNCOP_01258 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NMBLNCOP_01259 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NMBLNCOP_01260 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NMBLNCOP_01261 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NMBLNCOP_01262 3.2e-138 yqeM Q Methyltransferase
NMBLNCOP_01263 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMBLNCOP_01264 1.1e-104 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NMBLNCOP_01265 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
NMBLNCOP_01266 0.0 comEC S Competence protein ComEC
NMBLNCOP_01267 4.1e-15 S YqzM-like protein
NMBLNCOP_01268 7.3e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
NMBLNCOP_01269 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NMBLNCOP_01270 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NMBLNCOP_01271 2e-222 spoIIP M stage II sporulation protein P
NMBLNCOP_01272 2.7e-52 yqxA S Protein of unknown function (DUF3679)
NMBLNCOP_01273 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NMBLNCOP_01274 5.9e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
NMBLNCOP_01275 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NMBLNCOP_01276 1.5e-74 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NMBLNCOP_01277 0.0 dnaK O Heat shock 70 kDa protein
NMBLNCOP_01278 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NMBLNCOP_01279 5.4e-175 prmA J Methylates ribosomal protein L11
NMBLNCOP_01280 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NMBLNCOP_01281 1e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NMBLNCOP_01282 2.3e-157 yqeW P COG1283 Na phosphate symporter
NMBLNCOP_01283 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NMBLNCOP_01284 2.5e-61 yqeY S Yqey-like protein
NMBLNCOP_01285 6.5e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NMBLNCOP_01286 3.7e-121 yqfA S UPF0365 protein
NMBLNCOP_01287 1.3e-22 yqfB
NMBLNCOP_01288 2.7e-45 yqfC S sporulation protein YqfC
NMBLNCOP_01289 1.6e-184 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NMBLNCOP_01290 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
NMBLNCOP_01292 0.0 yqfF S membrane-associated HD superfamily hydrolase
NMBLNCOP_01293 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NMBLNCOP_01294 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NMBLNCOP_01295 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NMBLNCOP_01296 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NMBLNCOP_01297 8.4e-19 S YqzL-like protein
NMBLNCOP_01298 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
NMBLNCOP_01299 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NMBLNCOP_01300 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NMBLNCOP_01301 4.5e-112 ccpN K CBS domain
NMBLNCOP_01302 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NMBLNCOP_01303 4.5e-88 yaiI S Belongs to the UPF0178 family
NMBLNCOP_01304 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NMBLNCOP_01305 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NMBLNCOP_01306 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NMBLNCOP_01307 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
NMBLNCOP_01308 5.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NMBLNCOP_01309 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NMBLNCOP_01310 2.9e-14 yqfQ S YqfQ-like protein
NMBLNCOP_01311 3.2e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NMBLNCOP_01312 4.4e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NMBLNCOP_01313 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NMBLNCOP_01314 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NMBLNCOP_01315 4.2e-77 zur P Belongs to the Fur family
NMBLNCOP_01316 2.7e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NMBLNCOP_01317 4.3e-62 yqfX S membrane
NMBLNCOP_01318 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NMBLNCOP_01319 2.6e-46 yqfZ M LysM domain
NMBLNCOP_01320 2.5e-130 yqgB S Protein of unknown function (DUF1189)
NMBLNCOP_01321 4e-73 yqgC S protein conserved in bacteria
NMBLNCOP_01322 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NMBLNCOP_01323 2.5e-231 yqgE EGP Major facilitator superfamily
NMBLNCOP_01324 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NMBLNCOP_01325 2.6e-150 pstS P Phosphate
NMBLNCOP_01326 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NMBLNCOP_01327 7.4e-158 pstA P Phosphate transport system permease
NMBLNCOP_01328 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMBLNCOP_01329 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMBLNCOP_01330 7e-75 yqzC S YceG-like family
NMBLNCOP_01331 3.5e-50 yqzD
NMBLNCOP_01333 2.3e-196 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NMBLNCOP_01334 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NMBLNCOP_01335 6.7e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NMBLNCOP_01336 2.5e-09 yqgO
NMBLNCOP_01337 1e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NMBLNCOP_01338 4.3e-33 yqgQ S Protein conserved in bacteria
NMBLNCOP_01339 5.8e-180 glcK 2.7.1.2 G Glucokinase
NMBLNCOP_01340 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMBLNCOP_01341 1.1e-219 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NMBLNCOP_01342 5.1e-198 yqgU
NMBLNCOP_01343 6.9e-50 yqgV S Thiamine-binding protein
NMBLNCOP_01344 8.9e-23 yqgW S Protein of unknown function (DUF2759)
NMBLNCOP_01345 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NMBLNCOP_01346 1.8e-37 yqgY S Protein of unknown function (DUF2626)
NMBLNCOP_01347 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NMBLNCOP_01349 8.6e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMBLNCOP_01350 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NMBLNCOP_01351 7.2e-175 corA P Mg2 transporter protein
NMBLNCOP_01353 5.6e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NMBLNCOP_01354 2.4e-171 comGB NU COG1459 Type II secretory pathway, component PulF
NMBLNCOP_01355 1.5e-46 comGC U Required for transformation and DNA binding
NMBLNCOP_01356 1.4e-69 gspH NU protein transport across the cell outer membrane
NMBLNCOP_01357 3.1e-59 comGE
NMBLNCOP_01358 6.1e-48 comGF U Putative Competence protein ComGF
NMBLNCOP_01359 8.8e-44 S ComG operon protein 7
NMBLNCOP_01360 5.2e-26 yqzE S YqzE-like protein
NMBLNCOP_01361 7.3e-54 yqzG S Protein of unknown function (DUF3889)
NMBLNCOP_01362 6.3e-113 yqxM
NMBLNCOP_01363 6.7e-59 sipW 3.4.21.89 U Signal peptidase
NMBLNCOP_01364 7.3e-141 tasA S Cell division protein FtsN
NMBLNCOP_01365 1e-54 sinR K transcriptional
NMBLNCOP_01366 1.2e-24 sinI S Anti-repressor SinI
NMBLNCOP_01367 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
NMBLNCOP_01368 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NMBLNCOP_01369 2.1e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NMBLNCOP_01370 9.3e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NMBLNCOP_01371 5.3e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NMBLNCOP_01372 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
NMBLNCOP_01373 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NMBLNCOP_01374 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NMBLNCOP_01375 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
NMBLNCOP_01376 3.8e-61 yqhP
NMBLNCOP_01377 8.8e-173 yqhQ S Protein of unknown function (DUF1385)
NMBLNCOP_01378 6.6e-93 yqhR S Conserved membrane protein YqhR
NMBLNCOP_01379 7.2e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NMBLNCOP_01380 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NMBLNCOP_01381 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NMBLNCOP_01382 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NMBLNCOP_01383 1e-170 spoIIIAA S stage III sporulation protein AA
NMBLNCOP_01384 4.1e-84 spoIIIAB S Stage III sporulation protein
NMBLNCOP_01385 7.6e-29 spoIIIAC S stage III sporulation protein AC
NMBLNCOP_01386 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NMBLNCOP_01387 2.9e-197 spoIIIAE S stage III sporulation protein AE
NMBLNCOP_01388 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NMBLNCOP_01389 2.2e-109 spoIIIAG S stage III sporulation protein AG
NMBLNCOP_01390 9.9e-91 spoIIIAH S SpoIIIAH-like protein
NMBLNCOP_01391 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NMBLNCOP_01392 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NMBLNCOP_01393 2.1e-67 yqhY S protein conserved in bacteria
NMBLNCOP_01394 7.4e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NMBLNCOP_01395 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NMBLNCOP_01396 3.2e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMBLNCOP_01397 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMBLNCOP_01398 6.5e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NMBLNCOP_01399 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NMBLNCOP_01400 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NMBLNCOP_01401 1.7e-78 argR K Regulates arginine biosynthesis genes
NMBLNCOP_01402 3.5e-305 recN L May be involved in recombinational repair of damaged DNA
NMBLNCOP_01403 8e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
NMBLNCOP_01404 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NMBLNCOP_01406 1.2e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NMBLNCOP_01407 6e-27
NMBLNCOP_01408 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NMBLNCOP_01409 8.4e-131 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NMBLNCOP_01410 6.5e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
NMBLNCOP_01411 1e-156 hbdA 1.1.1.157 I Dehydrogenase
NMBLNCOP_01412 9.7e-211 mmgC I acyl-CoA dehydrogenase
NMBLNCOP_01413 4e-209 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NMBLNCOP_01414 6.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NMBLNCOP_01415 2.8e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NMBLNCOP_01416 4e-34 yqzF S Protein of unknown function (DUF2627)
NMBLNCOP_01417 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NMBLNCOP_01418 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NMBLNCOP_01419 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NMBLNCOP_01420 2.7e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NMBLNCOP_01421 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NMBLNCOP_01422 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NMBLNCOP_01423 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMBLNCOP_01424 2.6e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMBLNCOP_01425 2.6e-152 bmrR K helix_turn_helix, mercury resistance
NMBLNCOP_01426 7.9e-208 norA EGP Major facilitator Superfamily
NMBLNCOP_01427 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NMBLNCOP_01428 9.3e-77 yqiW S Belongs to the UPF0403 family
NMBLNCOP_01429 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
NMBLNCOP_01430 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NMBLNCOP_01431 7.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NMBLNCOP_01432 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
NMBLNCOP_01433 2.2e-96 yqjB S protein conserved in bacteria
NMBLNCOP_01435 2.3e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NMBLNCOP_01436 1.2e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NMBLNCOP_01437 2.8e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NMBLNCOP_01438 2e-137 yqjF S Uncharacterized conserved protein (COG2071)
NMBLNCOP_01439 1.9e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMBLNCOP_01440 4.5e-24 yqzJ
NMBLNCOP_01441 2e-233 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMBLNCOP_01442 4.5e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NMBLNCOP_01443 2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NMBLNCOP_01444 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NMBLNCOP_01445 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NMBLNCOP_01446 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMBLNCOP_01447 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NMBLNCOP_01448 0.0 rocB E arginine degradation protein
NMBLNCOP_01449 1.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMBLNCOP_01450 1.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NMBLNCOP_01451 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NMBLNCOP_01452 3.9e-259 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NMBLNCOP_01453 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
NMBLNCOP_01454 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMBLNCOP_01456 1.3e-224 yqjV G Major Facilitator Superfamily
NMBLNCOP_01458 5.4e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMBLNCOP_01459 1.4e-48 S YolD-like protein
NMBLNCOP_01460 6.2e-87 yqjY K acetyltransferase
NMBLNCOP_01461 8.9e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NMBLNCOP_01462 3.5e-191 yqkA K GrpB protein
NMBLNCOP_01463 2.8e-54 yqkB S Belongs to the HesB IscA family
NMBLNCOP_01464 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NMBLNCOP_01465 2.1e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NMBLNCOP_01466 3.1e-12 yqkE S Protein of unknown function (DUF3886)
NMBLNCOP_01467 6.3e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NMBLNCOP_01469 5.8e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NMBLNCOP_01470 1.5e-219 yqxK 3.6.4.12 L DNA helicase
NMBLNCOP_01471 4.5e-58 ansR K Transcriptional regulator
NMBLNCOP_01472 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
NMBLNCOP_01473 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NMBLNCOP_01474 4.1e-227 mleN C Na H antiporter
NMBLNCOP_01475 5.5e-242 mleA 1.1.1.38 C malic enzyme
NMBLNCOP_01476 1.9e-30 yqkK
NMBLNCOP_01477 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NMBLNCOP_01478 2.4e-80 fur P Belongs to the Fur family
NMBLNCOP_01479 3.7e-37 S Protein of unknown function (DUF4227)
NMBLNCOP_01480 2.6e-166 xerD L recombinase XerD
NMBLNCOP_01481 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NMBLNCOP_01482 8.4e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NMBLNCOP_01483 3.4e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NMBLNCOP_01484 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NMBLNCOP_01485 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NMBLNCOP_01486 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMBLNCOP_01487 9.6e-112 spoVAA S Stage V sporulation protein AA
NMBLNCOP_01488 1e-67 spoVAB S Stage V sporulation protein AB
NMBLNCOP_01489 2.3e-78 spoVAC S stage V sporulation protein AC
NMBLNCOP_01490 9e-192 spoVAD I Stage V sporulation protein AD
NMBLNCOP_01491 2.2e-57 spoVAEB S stage V sporulation protein
NMBLNCOP_01492 1.4e-110 spoVAEA S stage V sporulation protein
NMBLNCOP_01493 3.1e-273 spoVAF EG Stage V sporulation protein AF
NMBLNCOP_01494 8.8e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NMBLNCOP_01495 3.6e-149 ypuA S Secreted protein
NMBLNCOP_01496 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMBLNCOP_01500 5.6e-07
NMBLNCOP_01501 1.9e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMBLNCOP_01503 1e-07 eaeH M Domain of Unknown Function (DUF1259)
NMBLNCOP_01507 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NMBLNCOP_01508 6.2e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NMBLNCOP_01509 7.8e-55 ypuD
NMBLNCOP_01510 2.9e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NMBLNCOP_01511 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
NMBLNCOP_01512 4.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NMBLNCOP_01513 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NMBLNCOP_01514 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMBLNCOP_01515 3.2e-92 ypuF S Domain of unknown function (DUF309)
NMBLNCOP_01516 2.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NMBLNCOP_01517 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NMBLNCOP_01518 7.6e-97 ypuI S Protein of unknown function (DUF3907)
NMBLNCOP_01519 3e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NMBLNCOP_01520 3.5e-103 spmA S Spore maturation protein
NMBLNCOP_01521 1.9e-87 spmB S Spore maturation protein
NMBLNCOP_01522 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NMBLNCOP_01523 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NMBLNCOP_01524 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NMBLNCOP_01525 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NMBLNCOP_01526 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMBLNCOP_01527 0.0 resE 2.7.13.3 T Histidine kinase
NMBLNCOP_01528 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NMBLNCOP_01529 3.1e-190 rsiX
NMBLNCOP_01530 7.2e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NMBLNCOP_01531 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMBLNCOP_01532 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NMBLNCOP_01533 4.7e-41 fer C Ferredoxin
NMBLNCOP_01534 5.1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
NMBLNCOP_01535 1.7e-284 recQ 3.6.4.12 L DNA helicase
NMBLNCOP_01536 1.1e-99 ypbD S metal-dependent membrane protease
NMBLNCOP_01537 1.7e-78 ypbE M Lysin motif
NMBLNCOP_01538 2.8e-81 ypbF S Protein of unknown function (DUF2663)
NMBLNCOP_01539 4.4e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
NMBLNCOP_01540 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NMBLNCOP_01541 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NMBLNCOP_01542 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NMBLNCOP_01543 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
NMBLNCOP_01544 1.3e-152 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NMBLNCOP_01545 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NMBLNCOP_01546 1e-111 ypfA M Flagellar protein YcgR
NMBLNCOP_01547 1.8e-23 S Family of unknown function (DUF5359)
NMBLNCOP_01548 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NMBLNCOP_01549 2.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NMBLNCOP_01550 1.2e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NMBLNCOP_01551 1e-07 S YpzI-like protein
NMBLNCOP_01552 6.7e-102 yphA
NMBLNCOP_01553 3.3e-161 seaA S YIEGIA protein
NMBLNCOP_01554 1.6e-28 ypzH
NMBLNCOP_01555 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NMBLNCOP_01556 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NMBLNCOP_01557 1.2e-18 yphE S Protein of unknown function (DUF2768)
NMBLNCOP_01558 6e-137 yphF
NMBLNCOP_01559 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NMBLNCOP_01560 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NMBLNCOP_01561 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NMBLNCOP_01562 3.9e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NMBLNCOP_01563 1.6e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NMBLNCOP_01564 7.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NMBLNCOP_01565 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NMBLNCOP_01566 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NMBLNCOP_01567 4.2e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NMBLNCOP_01568 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NMBLNCOP_01569 1e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NMBLNCOP_01570 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NMBLNCOP_01571 2.4e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NMBLNCOP_01572 7.7e-167 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NMBLNCOP_01573 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NMBLNCOP_01574 7.9e-117 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NMBLNCOP_01575 4.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NMBLNCOP_01576 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NMBLNCOP_01577 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NMBLNCOP_01578 1.1e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NMBLNCOP_01579 1.6e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NMBLNCOP_01580 5.9e-233 S COG0457 FOG TPR repeat
NMBLNCOP_01581 1.1e-98 ypiB S Belongs to the UPF0302 family
NMBLNCOP_01582 1.4e-75 ypiF S Protein of unknown function (DUF2487)
NMBLNCOP_01583 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NMBLNCOP_01584 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NMBLNCOP_01585 9.6e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NMBLNCOP_01586 1.1e-99 ypjA S membrane
NMBLNCOP_01587 1e-142 ypjB S sporulation protein
NMBLNCOP_01588 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NMBLNCOP_01589 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NMBLNCOP_01590 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NMBLNCOP_01591 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NMBLNCOP_01592 4.9e-128 bshB1 S proteins, LmbE homologs
NMBLNCOP_01593 1.7e-207 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NMBLNCOP_01594 6.6e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NMBLNCOP_01595 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NMBLNCOP_01596 1.2e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NMBLNCOP_01597 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NMBLNCOP_01598 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NMBLNCOP_01599 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NMBLNCOP_01600 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NMBLNCOP_01601 8.4e-79 ypmB S protein conserved in bacteria
NMBLNCOP_01602 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NMBLNCOP_01603 1.7e-251 asnS 6.1.1.22 J asparaginyl-tRNA
NMBLNCOP_01604 5.7e-129 dnaD L DNA replication protein DnaD
NMBLNCOP_01605 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NMBLNCOP_01606 8.8e-92 ypoC
NMBLNCOP_01607 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NMBLNCOP_01608 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NMBLNCOP_01609 8.3e-187 yppC S Protein of unknown function (DUF2515)
NMBLNCOP_01612 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
NMBLNCOP_01614 1e-47 yppG S YppG-like protein
NMBLNCOP_01615 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
NMBLNCOP_01616 3.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NMBLNCOP_01617 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NMBLNCOP_01618 9.5e-236 yprB L RNase_H superfamily
NMBLNCOP_01619 2.8e-91 ypsA S Belongs to the UPF0398 family
NMBLNCOP_01620 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NMBLNCOP_01621 3.5e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NMBLNCOP_01623 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NMBLNCOP_01624 1.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMBLNCOP_01625 6.3e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NMBLNCOP_01626 1.5e-186 ptxS K transcriptional
NMBLNCOP_01627 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NMBLNCOP_01628 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NMBLNCOP_01629 6.6e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NMBLNCOP_01630 1.1e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NMBLNCOP_01631 2e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NMBLNCOP_01632 2.5e-226 pbuX F xanthine
NMBLNCOP_01633 7e-206 bcsA Q Naringenin-chalcone synthase
NMBLNCOP_01634 5.1e-87 ypbQ S protein conserved in bacteria
NMBLNCOP_01636 0.0 ypbR S Dynamin family
NMBLNCOP_01637 1e-38 ypbS S Protein of unknown function (DUF2533)
NMBLNCOP_01638 2e-07
NMBLNCOP_01639 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
NMBLNCOP_01641 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
NMBLNCOP_01642 7.7e-106 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NMBLNCOP_01643 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NMBLNCOP_01644 2.6e-27 ypeQ S Zinc-finger
NMBLNCOP_01645 8.1e-31 S Protein of unknown function (DUF2564)
NMBLNCOP_01646 3.8e-16 degR
NMBLNCOP_01647 7.9e-31 cspD K Cold-shock protein
NMBLNCOP_01648 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NMBLNCOP_01650 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NMBLNCOP_01651 3.2e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NMBLNCOP_01652 1.3e-105 ypgQ S phosphohydrolase
NMBLNCOP_01653 1.1e-150 ypgR C COG0694 Thioredoxin-like proteins and domains
NMBLNCOP_01654 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NMBLNCOP_01655 1.7e-75 yphP S Belongs to the UPF0403 family
NMBLNCOP_01656 6.5e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NMBLNCOP_01657 2.5e-112 ypjP S YpjP-like protein
NMBLNCOP_01658 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NMBLNCOP_01659 4.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NMBLNCOP_01660 3.7e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NMBLNCOP_01661 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NMBLNCOP_01662 4.2e-110 hlyIII S protein, Hemolysin III
NMBLNCOP_01663 2e-183 pspF K Transcriptional regulator
NMBLNCOP_01664 2e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NMBLNCOP_01665 8.9e-40 ypmP S Protein of unknown function (DUF2535)
NMBLNCOP_01666 4.6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NMBLNCOP_01667 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
NMBLNCOP_01668 1.1e-98 ypmS S protein conserved in bacteria
NMBLNCOP_01669 5.5e-29 ypmT S Uncharacterized ympT
NMBLNCOP_01670 1.2e-220 mepA V MATE efflux family protein
NMBLNCOP_01671 1.6e-70 ypoP K transcriptional
NMBLNCOP_01672 1.7e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NMBLNCOP_01673 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NMBLNCOP_01674 7.4e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
NMBLNCOP_01675 4.1e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NMBLNCOP_01676 1.3e-179 cgeB S Spore maturation protein
NMBLNCOP_01677 8.2e-64 cgeA
NMBLNCOP_01678 3.5e-38 cgeC
NMBLNCOP_01679 1.6e-254 cgeD M maturation of the outermost layer of the spore
NMBLNCOP_01680 4.6e-143 yiiD K acetyltransferase
NMBLNCOP_01681 4e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMBLNCOP_01682 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NMBLNCOP_01683 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NMBLNCOP_01684 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
NMBLNCOP_01685 7.9e-154 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NMBLNCOP_01686 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
NMBLNCOP_01687 6.4e-47 yokU S YokU-like protein, putative antitoxin
NMBLNCOP_01688 1.4e-36 yozE S Belongs to the UPF0346 family
NMBLNCOP_01689 6e-123 yodN
NMBLNCOP_01691 2.8e-24 yozD S YozD-like protein
NMBLNCOP_01692 2e-106 yodM 3.6.1.27 I Acid phosphatase homologues
NMBLNCOP_01693 3.6e-54 yodL S YodL-like
NMBLNCOP_01694 5.3e-09
NMBLNCOP_01695 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NMBLNCOP_01696 8.8e-137 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NMBLNCOP_01697 1.5e-23 yodI
NMBLNCOP_01698 6.3e-128 yodH Q Methyltransferase
NMBLNCOP_01699 4.1e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NMBLNCOP_01700 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMBLNCOP_01701 6.2e-28 S Protein of unknown function (DUF3311)
NMBLNCOP_01702 3.2e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
NMBLNCOP_01703 5.5e-112 mhqD S Carboxylesterase
NMBLNCOP_01704 1.4e-107 yodC C nitroreductase
NMBLNCOP_01705 4.4e-55 yodB K transcriptional
NMBLNCOP_01706 8e-64 yodA S tautomerase
NMBLNCOP_01707 6.5e-206 gntP EG COG2610 H gluconate symporter and related permeases
NMBLNCOP_01708 2e-09
NMBLNCOP_01709 5.5e-59 yozR S COG0071 Molecular chaperone (small heat shock protein)
NMBLNCOP_01710 6.6e-162 rarD S -transporter
NMBLNCOP_01711 1.5e-43
NMBLNCOP_01712 8.2e-60 yojF S Protein of unknown function (DUF1806)
NMBLNCOP_01713 2.1e-125 yojG S deacetylase
NMBLNCOP_01714 4.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMBLNCOP_01715 4.2e-245 norM V Multidrug efflux pump
NMBLNCOP_01717 5.8e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMBLNCOP_01718 9e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NMBLNCOP_01719 2.5e-196 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NMBLNCOP_01720 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NMBLNCOP_01721 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
NMBLNCOP_01722 0.0 yojO P Von Willebrand factor
NMBLNCOP_01723 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NMBLNCOP_01724 9.1e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NMBLNCOP_01725 5.1e-168 yocS S -transporter
NMBLNCOP_01726 2.4e-229 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NMBLNCOP_01727 6e-165 sodA 1.15.1.1 P Superoxide dismutase
NMBLNCOP_01728 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NMBLNCOP_01729 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NMBLNCOP_01730 2.7e-31 yozC
NMBLNCOP_01731 4.2e-56 yozO S Bacterial PH domain
NMBLNCOP_01732 1.9e-36 yocN
NMBLNCOP_01733 1.1e-40 yozN
NMBLNCOP_01734 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
NMBLNCOP_01735 6.2e-32
NMBLNCOP_01736 6.4e-54 yocL
NMBLNCOP_01737 9.7e-83 dksA T general stress protein
NMBLNCOP_01738 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NMBLNCOP_01739 0.0 recQ 3.6.4.12 L DNA helicase
NMBLNCOP_01740 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
NMBLNCOP_01741 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMBLNCOP_01742 7.1e-198 desK 2.7.13.3 T Histidine kinase
NMBLNCOP_01743 1.2e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NMBLNCOP_01744 6e-185 yocD 3.4.17.13 V peptidase S66
NMBLNCOP_01745 1.5e-91 yocC
NMBLNCOP_01746 4.1e-144
NMBLNCOP_01747 1.5e-92 yozB S membrane
NMBLNCOP_01748 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NMBLNCOP_01749 1e-51 czrA K transcriptional
NMBLNCOP_01750 2.2e-91 yobW
NMBLNCOP_01751 3.3e-172 yobV K WYL domain
NMBLNCOP_01752 3.6e-82 yobU K Bacterial transcription activator, effector binding domain
NMBLNCOP_01753 2.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NMBLNCOP_01754 6.2e-97 yobS K Transcriptional regulator
NMBLNCOP_01755 3.1e-141 yobR 2.3.1.1 J FR47-like protein
NMBLNCOP_01756 1.5e-127 yobQ K helix_turn_helix, arabinose operon control protein
NMBLNCOP_01757 3.5e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NMBLNCOP_01758 0.0 yobO M Pectate lyase superfamily protein
NMBLNCOP_01759 4.1e-275 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NMBLNCOP_01760 5.2e-20 yokH G SMI1 / KNR4 family
NMBLNCOP_01761 1.1e-33 yokH G SMI1 / KNR4 family
NMBLNCOP_01762 1.7e-39 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMBLNCOP_01767 8.8e-37 S TM2 domain
NMBLNCOP_01768 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NMBLNCOP_01769 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NMBLNCOP_01772 2.9e-165 bla 3.5.2.6 V beta-lactamase
NMBLNCOP_01773 1.4e-113 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NMBLNCOP_01774 2.7e-76 yoaW
NMBLNCOP_01775 3.7e-157 yijE EG EamA-like transporter family
NMBLNCOP_01776 8.6e-159 yoaU K LysR substrate binding domain
NMBLNCOP_01777 3.7e-148 yoaT S Protein of unknown function (DUF817)
NMBLNCOP_01778 4.4e-30 yozG K Transcriptional regulator
NMBLNCOP_01779 1.1e-73 yoaS S Protein of unknown function (DUF2975)
NMBLNCOP_01780 2.1e-171 yoaR V vancomycin resistance protein
NMBLNCOP_01781 2e-83
NMBLNCOP_01783 4.8e-51 yoaQ S Evidence 4 Homologs of previously reported genes of
NMBLNCOP_01784 6.6e-139 yoaP 3.1.3.18 K YoaP-like
NMBLNCOP_01786 3.9e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
NMBLNCOP_01789 1.9e-129 yoqW S Belongs to the SOS response-associated peptidase family
NMBLNCOP_01790 3.6e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NMBLNCOP_01791 1.5e-110 yoaK S Membrane
NMBLNCOP_01792 7.2e-132 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NMBLNCOP_01793 5.3e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NMBLNCOP_01794 2.2e-182 mcpU NT methyl-accepting chemotaxis protein
NMBLNCOP_01795 4.1e-36 S Protein of unknown function (DUF4025)
NMBLNCOP_01796 1e-12
NMBLNCOP_01797 5e-08 ywlA S Uncharacterised protein family (UPF0715)
NMBLNCOP_01798 6.5e-34 yoaF
NMBLNCOP_01799 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMBLNCOP_01800 3.7e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMBLNCOP_01801 3.6e-274 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NMBLNCOP_01802 5.8e-233 yoaB EGP Major facilitator Superfamily
NMBLNCOP_01803 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
NMBLNCOP_01804 9.7e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
NMBLNCOP_01805 3.7e-94 V ABC-2 family transporter protein
NMBLNCOP_01806 4.5e-127 V ABC-2 family transporter protein
NMBLNCOP_01807 3.3e-25 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMBLNCOP_01808 1.9e-133 yoxB
NMBLNCOP_01809 7.8e-38 yoxC S Bacterial protein of unknown function (DUF948)
NMBLNCOP_01810 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NMBLNCOP_01811 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NMBLNCOP_01812 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMBLNCOP_01813 6e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMBLNCOP_01814 7.8e-155 gltC K Transcriptional regulator
NMBLNCOP_01815 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NMBLNCOP_01816 5.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NMBLNCOP_01817 8e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NMBLNCOP_01818 2.6e-155 gltR1 K Transcriptional regulator
NMBLNCOP_01819 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NMBLNCOP_01820 3e-34 yoeD G Helix-turn-helix domain
NMBLNCOP_01821 6.5e-96 L Integrase
NMBLNCOP_01823 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
NMBLNCOP_01824 1.9e-245 yoeA V MATE efflux family protein
NMBLNCOP_01825 2.2e-187 yoxA 5.1.3.3 G Aldose 1-epimerase
NMBLNCOP_01826 7.5e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NMBLNCOP_01827 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMBLNCOP_01828 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMBLNCOP_01829 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMBLNCOP_01830 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMBLNCOP_01831 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NMBLNCOP_01832 1.1e-63 yngL S Protein of unknown function (DUF1360)
NMBLNCOP_01833 4.5e-304 yngK T Glycosyl hydrolase-like 10
NMBLNCOP_01834 1.6e-11 K Bacterial regulatory proteins, tetR family
NMBLNCOP_01835 9.8e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NMBLNCOP_01836 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NMBLNCOP_01837 2.1e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NMBLNCOP_01838 3.3e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NMBLNCOP_01839 1.5e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NMBLNCOP_01840 2.1e-135 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NMBLNCOP_01841 7.7e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NMBLNCOP_01842 3.6e-232 nrnB S phosphohydrolase (DHH superfamily)
NMBLNCOP_01843 5.5e-104 yngC S membrane-associated protein
NMBLNCOP_01844 1.2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NMBLNCOP_01845 1.3e-78 yngA S membrane
NMBLNCOP_01846 8.6e-295 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NMBLNCOP_01847 1.4e-247 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NMBLNCOP_01849 3.8e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NMBLNCOP_01850 5.3e-251 agcS E Sodium alanine symporter
NMBLNCOP_01851 1.3e-57 ynfC
NMBLNCOP_01852 2.3e-12
NMBLNCOP_01853 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMBLNCOP_01854 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMBLNCOP_01855 6.6e-69 yccU S CoA-binding protein
NMBLNCOP_01856 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NMBLNCOP_01857 4.1e-49 yneR S Belongs to the HesB IscA family
NMBLNCOP_01858 2.2e-53 yneQ
NMBLNCOP_01859 1.2e-73 yneP S Thioesterase-like superfamily
NMBLNCOP_01860 2.5e-34 tlp S Belongs to the Tlp family
NMBLNCOP_01861 3.1e-08 sspN S Small acid-soluble spore protein N family
NMBLNCOP_01863 9.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NMBLNCOP_01864 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NMBLNCOP_01865 2.5e-14 sspO S Belongs to the SspO family
NMBLNCOP_01866 3.9e-19 sspP S Belongs to the SspP family
NMBLNCOP_01867 2.2e-63 hspX O Spore coat protein
NMBLNCOP_01868 4.2e-74 yneK S Protein of unknown function (DUF2621)
NMBLNCOP_01869 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NMBLNCOP_01870 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NMBLNCOP_01871 1.2e-126 ccdA O cytochrome c biogenesis protein
NMBLNCOP_01872 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NMBLNCOP_01873 1.8e-28 yneF S UPF0154 protein
NMBLNCOP_01874 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NMBLNCOP_01875 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NMBLNCOP_01876 1.3e-32 ynzC S UPF0291 protein
NMBLNCOP_01877 6.6e-111 yneB L resolvase
NMBLNCOP_01878 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NMBLNCOP_01879 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NMBLNCOP_01880 5.8e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NMBLNCOP_01881 1.7e-73 yndM S Protein of unknown function (DUF2512)
NMBLNCOP_01882 1.2e-137 yndL S Replication protein
NMBLNCOP_01884 3e-306 yndJ S YndJ-like protein
NMBLNCOP_01885 2.7e-114 yndH S Domain of unknown function (DUF4166)
NMBLNCOP_01886 2e-149 yndG S DoxX-like family
NMBLNCOP_01887 2e-214 gerLC S Spore germination protein
NMBLNCOP_01888 2.5e-195 gerAB U Spore germination
NMBLNCOP_01889 3.2e-281 gerAA EG Spore germination protein
NMBLNCOP_01892 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NMBLNCOP_01893 5.3e-71
NMBLNCOP_01894 7.9e-25 tatA U protein secretion
NMBLNCOP_01897 1.1e-133 S Domain of unknown function, YrpD
NMBLNCOP_01899 9.5e-163 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NMBLNCOP_01902 5.2e-15
NMBLNCOP_01903 1.9e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NMBLNCOP_01904 2e-82 yncE S Protein of unknown function (DUF2691)
NMBLNCOP_01905 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMBLNCOP_01906 5.2e-254 iolT EGP Major facilitator Superfamily
NMBLNCOP_01907 6.4e-111 yokF 3.1.31.1 L RNA catabolic process
NMBLNCOP_01908 4.8e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NMBLNCOP_01909 3.2e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NMBLNCOP_01910 4.7e-213 xylR GK ROK family
NMBLNCOP_01911 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NMBLNCOP_01912 1.8e-254 xynT G MFS/sugar transport protein
NMBLNCOP_01913 5.5e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NMBLNCOP_01916 8.3e-45 ynaF
NMBLNCOP_01917 1.5e-76 S CAAX protease self-immunity
NMBLNCOP_01918 3.5e-94 ynaD J Acetyltransferase (GNAT) domain
NMBLNCOP_01919 1.1e-141 ynaC
NMBLNCOP_01920 1.7e-93 G SMI1-KNR4 cell-wall
NMBLNCOP_01921 2.1e-36
NMBLNCOP_01922 6.5e-124
NMBLNCOP_01923 5.6e-30
NMBLNCOP_01924 7e-261 glnA 6.3.1.2 E glutamine synthetase
NMBLNCOP_01925 1.1e-68 glnR K transcriptional
NMBLNCOP_01926 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NMBLNCOP_01927 7.9e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NMBLNCOP_01928 1.7e-176 spoVK O stage V sporulation protein K
NMBLNCOP_01929 2.3e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMBLNCOP_01930 1.7e-108 ymaB
NMBLNCOP_01931 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMBLNCOP_01932 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMBLNCOP_01933 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NMBLNCOP_01934 4.5e-22 ymzA
NMBLNCOP_01935 6.3e-23
NMBLNCOP_01936 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NMBLNCOP_01937 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NMBLNCOP_01938 1.9e-44 ymaF S YmaF family
NMBLNCOP_01940 5.4e-50 ebrA P Small Multidrug Resistance protein
NMBLNCOP_01941 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NMBLNCOP_01942 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
NMBLNCOP_01943 1.7e-125 ymaC S Replication protein
NMBLNCOP_01944 1.9e-07 K Transcriptional regulator
NMBLNCOP_01945 8.6e-251 aprX O Belongs to the peptidase S8 family
NMBLNCOP_01946 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
NMBLNCOP_01947 4.4e-61 ymzB
NMBLNCOP_01948 7.4e-233 cypA C Cytochrome P450
NMBLNCOP_01949 0.0 pks13 HQ Beta-ketoacyl synthase
NMBLNCOP_01950 0.0 dhbF IQ polyketide synthase
NMBLNCOP_01951 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
NMBLNCOP_01952 0.0 pfaA Q Polyketide synthase of type I
NMBLNCOP_01953 0.0 rhiB IQ polyketide synthase
NMBLNCOP_01954 1e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NMBLNCOP_01955 5.5e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
NMBLNCOP_01956 1.5e-244 pksG 2.3.3.10 I synthase
NMBLNCOP_01957 2.1e-235 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NMBLNCOP_01958 5.3e-37 acpK IQ Phosphopantetheine attachment site
NMBLNCOP_01959 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NMBLNCOP_01960 1.7e-184 pksD Q Acyl transferase domain
NMBLNCOP_01962 7.5e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NMBLNCOP_01963 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
NMBLNCOP_01964 4.4e-109 pksA K Transcriptional regulator
NMBLNCOP_01965 3.5e-97 ymcC S Membrane
NMBLNCOP_01967 4.1e-67 S Regulatory protein YrvL
NMBLNCOP_01969 4.6e-70 S Phage terminase, small subunit
NMBLNCOP_01970 1.1e-19
NMBLNCOP_01971 9.4e-62 S HNH endonuclease
NMBLNCOP_01975 9.9e-32 S YjcQ protein
NMBLNCOP_01976 1.8e-32 S Domain of unknown function (DUF4145)
NMBLNCOP_01977 6.6e-43 L Phage integrase family
NMBLNCOP_01978 6.4e-14 L Phage integrase family
NMBLNCOP_01979 2.1e-47 wecC 1.1.1.336 M ArpU family transcriptional regulator
NMBLNCOP_01982 4.9e-51 V HNH nucleases
NMBLNCOP_01983 6.7e-102 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NMBLNCOP_01986 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NMBLNCOP_01987 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NMBLNCOP_01988 2.2e-88 cotE S Spore coat protein
NMBLNCOP_01989 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NMBLNCOP_01990 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NMBLNCOP_01991 1.4e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NMBLNCOP_01992 3.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NMBLNCOP_01993 1.2e-36 spoVS S Stage V sporulation protein S
NMBLNCOP_01994 1.9e-152 ymdB S protein conserved in bacteria
NMBLNCOP_01995 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NMBLNCOP_01996 2.2e-213 pbpX V Beta-lactamase
NMBLNCOP_01997 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NMBLNCOP_01998 5.6e-236 cinA 3.5.1.42 S Belongs to the CinA family
NMBLNCOP_01999 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NMBLNCOP_02000 3.5e-118 ymfM S protein conserved in bacteria
NMBLNCOP_02001 4.6e-143 ymfK S Protein of unknown function (DUF3388)
NMBLNCOP_02002 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NMBLNCOP_02003 1.7e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NMBLNCOP_02004 1.1e-239 ymfH S zinc protease
NMBLNCOP_02005 7.8e-233 ymfF S Peptidase M16
NMBLNCOP_02006 1.5e-206 ymfD EGP Major facilitator Superfamily
NMBLNCOP_02007 1.4e-133 ymfC K Transcriptional regulator
NMBLNCOP_02008 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NMBLNCOP_02009 4.4e-32 S YlzJ-like protein
NMBLNCOP_02010 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NMBLNCOP_02011 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMBLNCOP_02012 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NMBLNCOP_02013 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NMBLNCOP_02014 4.1e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NMBLNCOP_02015 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NMBLNCOP_02016 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NMBLNCOP_02017 2.6e-42 ymxH S YlmC YmxH family
NMBLNCOP_02018 4.4e-233 pepR S Belongs to the peptidase M16 family
NMBLNCOP_02019 1e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NMBLNCOP_02020 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NMBLNCOP_02021 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NMBLNCOP_02022 1.5e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NMBLNCOP_02023 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NMBLNCOP_02024 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NMBLNCOP_02025 3.9e-44 ylxP S protein conserved in bacteria
NMBLNCOP_02026 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NMBLNCOP_02027 3.4e-46 ylxQ J ribosomal protein
NMBLNCOP_02028 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NMBLNCOP_02029 1.1e-203 nusA K Participates in both transcription termination and antitermination
NMBLNCOP_02030 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NMBLNCOP_02031 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMBLNCOP_02032 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NMBLNCOP_02033 1.7e-232 rasP M zinc metalloprotease
NMBLNCOP_02034 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NMBLNCOP_02035 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NMBLNCOP_02036 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NMBLNCOP_02037 1.4e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NMBLNCOP_02038 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NMBLNCOP_02039 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NMBLNCOP_02040 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NMBLNCOP_02041 8.2e-77 ylxL
NMBLNCOP_02042 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMBLNCOP_02043 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NMBLNCOP_02044 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NMBLNCOP_02045 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NMBLNCOP_02046 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NMBLNCOP_02047 2.2e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NMBLNCOP_02048 1.7e-157 flhG D Belongs to the ParA family
NMBLNCOP_02049 7.5e-200 flhF N Flagellar biosynthesis regulator FlhF
NMBLNCOP_02050 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NMBLNCOP_02051 6.9e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NMBLNCOP_02052 5.2e-131 fliR N Flagellar biosynthetic protein FliR
NMBLNCOP_02053 2.2e-36 fliQ N Role in flagellar biosynthesis
NMBLNCOP_02054 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NMBLNCOP_02055 5.1e-95 fliZ N Flagellar biosynthesis protein, FliO
NMBLNCOP_02056 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NMBLNCOP_02057 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NMBLNCOP_02058 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NMBLNCOP_02059 1e-48 fliL N Controls the rotational direction of flagella during chemotaxis
NMBLNCOP_02060 2.4e-139 flgG N Flagellar basal body rod
NMBLNCOP_02061 2.3e-72 flgD N Flagellar basal body rod modification protein
NMBLNCOP_02062 1.4e-190 fliK N Flagellar hook-length control protein
NMBLNCOP_02063 2.2e-36 ylxF S MgtE intracellular N domain
NMBLNCOP_02064 1.5e-69 fliJ N Flagellar biosynthesis chaperone
NMBLNCOP_02065 2.1e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NMBLNCOP_02066 5.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NMBLNCOP_02067 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NMBLNCOP_02068 2.6e-254 fliF N The M ring may be actively involved in energy transduction
NMBLNCOP_02069 1.9e-31 fliE N Flagellar hook-basal body
NMBLNCOP_02070 5.8e-74 flgC N Belongs to the flagella basal body rod proteins family
NMBLNCOP_02071 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NMBLNCOP_02072 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NMBLNCOP_02073 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NMBLNCOP_02074 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NMBLNCOP_02075 2.5e-169 xerC L tyrosine recombinase XerC
NMBLNCOP_02076 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NMBLNCOP_02077 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMBLNCOP_02078 3e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NMBLNCOP_02079 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NMBLNCOP_02080 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NMBLNCOP_02081 5.1e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NMBLNCOP_02082 9.4e-282 ylqG
NMBLNCOP_02083 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMBLNCOP_02084 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NMBLNCOP_02085 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NMBLNCOP_02086 7.8e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NMBLNCOP_02087 1e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NMBLNCOP_02088 6.3e-61 ylqD S YlqD protein
NMBLNCOP_02089 4.5e-36 ylqC S Belongs to the UPF0109 family
NMBLNCOP_02090 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NMBLNCOP_02091 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NMBLNCOP_02092 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NMBLNCOP_02093 2.9e-87
NMBLNCOP_02094 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NMBLNCOP_02095 0.0 smc D Required for chromosome condensation and partitioning
NMBLNCOP_02096 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NMBLNCOP_02097 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMBLNCOP_02098 5.1e-128 IQ reductase
NMBLNCOP_02099 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NMBLNCOP_02100 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NMBLNCOP_02101 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NMBLNCOP_02102 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NMBLNCOP_02103 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NMBLNCOP_02104 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NMBLNCOP_02105 7.3e-300 yloV S kinase related to dihydroxyacetone kinase
NMBLNCOP_02106 5.5e-59 asp S protein conserved in bacteria
NMBLNCOP_02107 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NMBLNCOP_02108 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NMBLNCOP_02109 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NMBLNCOP_02110 2.1e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NMBLNCOP_02111 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NMBLNCOP_02112 1.6e-140 stp 3.1.3.16 T phosphatase
NMBLNCOP_02113 9e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NMBLNCOP_02114 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NMBLNCOP_02115 6.1e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NMBLNCOP_02116 1.5e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NMBLNCOP_02117 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMBLNCOP_02118 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NMBLNCOP_02119 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NMBLNCOP_02120 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NMBLNCOP_02121 1.5e-40 ylzA S Belongs to the UPF0296 family
NMBLNCOP_02122 2.4e-156 yloC S stress-induced protein
NMBLNCOP_02123 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NMBLNCOP_02124 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NMBLNCOP_02125 1.4e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NMBLNCOP_02126 5.8e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NMBLNCOP_02127 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NMBLNCOP_02128 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NMBLNCOP_02129 4.2e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NMBLNCOP_02130 9.2e-179 cysP P phosphate transporter
NMBLNCOP_02131 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NMBLNCOP_02133 3.6e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NMBLNCOP_02134 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NMBLNCOP_02135 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NMBLNCOP_02136 2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NMBLNCOP_02137 0.0 carB 6.3.5.5 F Belongs to the CarB family
NMBLNCOP_02138 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NMBLNCOP_02139 4.6e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NMBLNCOP_02140 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NMBLNCOP_02141 2.6e-231 pyrP F Xanthine uracil
NMBLNCOP_02142 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NMBLNCOP_02143 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMBLNCOP_02144 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NMBLNCOP_02145 1.3e-63 dksA T COG1734 DnaK suppressor protein
NMBLNCOP_02146 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NMBLNCOP_02147 2.6e-67 divIVA D Cell division initiation protein
NMBLNCOP_02148 7.5e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NMBLNCOP_02149 2.8e-39 yggT S membrane
NMBLNCOP_02150 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NMBLNCOP_02151 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NMBLNCOP_02152 2.4e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NMBLNCOP_02153 2.4e-37 ylmC S sporulation protein
NMBLNCOP_02154 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
NMBLNCOP_02155 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NMBLNCOP_02156 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMBLNCOP_02157 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMBLNCOP_02158 1.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NMBLNCOP_02159 0.0 bpr O COG1404 Subtilisin-like serine proteases
NMBLNCOP_02160 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NMBLNCOP_02161 3.5e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NMBLNCOP_02162 6.2e-58 sbp S small basic protein
NMBLNCOP_02163 8.2e-117 ylxX S protein conserved in bacteria
NMBLNCOP_02164 4.1e-103 ylxW S protein conserved in bacteria
NMBLNCOP_02165 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NMBLNCOP_02166 5.3e-167 murB 1.3.1.98 M cell wall formation
NMBLNCOP_02167 1.6e-199 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NMBLNCOP_02168 5.7e-186 spoVE D Belongs to the SEDS family
NMBLNCOP_02169 1.3e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NMBLNCOP_02170 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NMBLNCOP_02171 1.2e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NMBLNCOP_02172 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NMBLNCOP_02173 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NMBLNCOP_02174 3.7e-44 ftsL D Essential cell division protein
NMBLNCOP_02175 4.7e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NMBLNCOP_02176 1.9e-77 mraZ K Belongs to the MraZ family
NMBLNCOP_02177 2.7e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NMBLNCOP_02178 1.6e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NMBLNCOP_02179 1.5e-88 ylbP K n-acetyltransferase
NMBLNCOP_02180 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NMBLNCOP_02181 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NMBLNCOP_02182 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
NMBLNCOP_02184 2.8e-235 ylbM S Belongs to the UPF0348 family
NMBLNCOP_02185 2e-186 ylbL T Belongs to the peptidase S16 family
NMBLNCOP_02186 1.3e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
NMBLNCOP_02187 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
NMBLNCOP_02188 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NMBLNCOP_02189 5.4e-98 rsmD 2.1.1.171 L Methyltransferase
NMBLNCOP_02190 3.7e-38 ylbG S UPF0298 protein
NMBLNCOP_02191 1.8e-75 ylbF S Belongs to the UPF0342 family
NMBLNCOP_02192 6.7e-37 ylbE S YlbE-like protein
NMBLNCOP_02193 4.1e-63 ylbD S Putative coat protein
NMBLNCOP_02194 4.3e-200 ylbC S protein with SCP PR1 domains
NMBLNCOP_02195 2.6e-74 ylbB T COG0517 FOG CBS domain
NMBLNCOP_02196 7e-62 ylbA S YugN-like family
NMBLNCOP_02197 1.7e-165 ctaG S cytochrome c oxidase
NMBLNCOP_02198 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NMBLNCOP_02199 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NMBLNCOP_02200 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NMBLNCOP_02201 1.5e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NMBLNCOP_02202 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NMBLNCOP_02203 3.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NMBLNCOP_02204 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NMBLNCOP_02205 2.7e-211 ftsW D Belongs to the SEDS family
NMBLNCOP_02206 8.7e-44 ylaN S Belongs to the UPF0358 family
NMBLNCOP_02207 8e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NMBLNCOP_02208 1.1e-83 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NMBLNCOP_02209 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NMBLNCOP_02210 2.3e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMBLNCOP_02211 2.5e-32 ylaI S protein conserved in bacteria
NMBLNCOP_02212 4.2e-47 ylaH S YlaH-like protein
NMBLNCOP_02213 0.0 typA T GTP-binding protein TypA
NMBLNCOP_02214 8.2e-22 S Family of unknown function (DUF5325)
NMBLNCOP_02215 2.6e-37 ylaE
NMBLNCOP_02216 9.1e-12 sigC S Putative zinc-finger
NMBLNCOP_02217 1.8e-90 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NMBLNCOP_02218 2.7e-42 ylaB
NMBLNCOP_02219 0.0 ylaA
NMBLNCOP_02220 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NMBLNCOP_02221 3.5e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NMBLNCOP_02222 2e-77 ykzC S Acetyltransferase (GNAT) family
NMBLNCOP_02223 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
NMBLNCOP_02224 7.1e-26 ykzI
NMBLNCOP_02225 2.1e-117 yktB S Belongs to the UPF0637 family
NMBLNCOP_02226 5.9e-42 yktA S Belongs to the UPF0223 family
NMBLNCOP_02227 3.5e-277 speA 4.1.1.19 E Arginine
NMBLNCOP_02228 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NMBLNCOP_02229 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NMBLNCOP_02230 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMBLNCOP_02231 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMBLNCOP_02232 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NMBLNCOP_02233 9.4e-113 recN L Putative cell-wall binding lipoprotein
NMBLNCOP_02235 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NMBLNCOP_02236 1.4e-147 ykrA S hydrolases of the HAD superfamily
NMBLNCOP_02237 8.2e-31 ykzG S Belongs to the UPF0356 family
NMBLNCOP_02238 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMBLNCOP_02239 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NMBLNCOP_02240 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NMBLNCOP_02241 6.1e-154 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NMBLNCOP_02242 1.3e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NMBLNCOP_02243 1.5e-43 abrB K of stationary sporulation gene expression
NMBLNCOP_02244 7.7e-183 mreB D Rod-share determining protein MreBH
NMBLNCOP_02245 1.1e-12 S Uncharacterized protein YkpC
NMBLNCOP_02246 1e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NMBLNCOP_02247 2e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NMBLNCOP_02248 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NMBLNCOP_02249 8.1e-39 ykoA
NMBLNCOP_02250 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NMBLNCOP_02251 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NMBLNCOP_02252 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NMBLNCOP_02253 2.6e-135 fruR K Transcriptional regulator
NMBLNCOP_02254 1.2e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NMBLNCOP_02255 5.5e-124 macB V ABC transporter, ATP-binding protein
NMBLNCOP_02256 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMBLNCOP_02257 2.5e-116 yknW S Yip1 domain
NMBLNCOP_02258 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMBLNCOP_02259 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMBLNCOP_02260 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NMBLNCOP_02261 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NMBLNCOP_02262 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NMBLNCOP_02263 3.4e-244 moeA 2.10.1.1 H molybdopterin
NMBLNCOP_02264 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NMBLNCOP_02265 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NMBLNCOP_02266 3.5e-145 yknT
NMBLNCOP_02267 1.5e-93 rok K Repressor of ComK
NMBLNCOP_02268 2.4e-80 ykuV CO thiol-disulfide
NMBLNCOP_02269 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NMBLNCOP_02270 8.8e-142 ykuT M Mechanosensitive ion channel
NMBLNCOP_02271 9e-37 ykuS S Belongs to the UPF0180 family
NMBLNCOP_02272 1.9e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NMBLNCOP_02273 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NMBLNCOP_02274 3.5e-79 fld C Flavodoxin
NMBLNCOP_02275 3e-175 ykuO
NMBLNCOP_02276 5e-84 fld C Flavodoxin domain
NMBLNCOP_02277 3.5e-168 ccpC K Transcriptional regulator
NMBLNCOP_02278 1.6e-76 ykuL S CBS domain
NMBLNCOP_02279 3.9e-27 ykzF S Antirepressor AbbA
NMBLNCOP_02280 4.4e-94 ykuK S Ribonuclease H-like
NMBLNCOP_02281 3.9e-37 ykuJ S protein conserved in bacteria
NMBLNCOP_02282 2e-233 ykuI T Diguanylate phosphodiesterase
NMBLNCOP_02283 4.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMBLNCOP_02284 9.4e-166 ykuE S Metallophosphoesterase
NMBLNCOP_02285 1.8e-87 ykuD S protein conserved in bacteria
NMBLNCOP_02286 6.2e-238 ykuC EGP Major facilitator Superfamily
NMBLNCOP_02287 1.8e-83 ykyB S YkyB-like protein
NMBLNCOP_02288 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NMBLNCOP_02289 2.2e-15
NMBLNCOP_02290 4.4e-222 patA 2.6.1.1 E Aminotransferase
NMBLNCOP_02291 0.0 pilS 2.7.13.3 T Histidine kinase
NMBLNCOP_02292 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NMBLNCOP_02293 1.8e-123 ykwD J protein with SCP PR1 domains
NMBLNCOP_02294 9.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NMBLNCOP_02295 1.5e-251 mcpC NT chemotaxis protein
NMBLNCOP_02296 5.4e-127 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMBLNCOP_02297 9.7e-202 splB 4.1.99.14 L Spore photoproduct lyase
NMBLNCOP_02298 7.2e-39 splA S Transcriptional regulator
NMBLNCOP_02299 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NMBLNCOP_02300 2.1e-39 ptsH G phosphocarrier protein HPr
NMBLNCOP_02301 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMBLNCOP_02302 7.6e-128 glcT K antiterminator
NMBLNCOP_02303 3.7e-179 ykvZ 5.1.1.1 K Transcriptional regulator
NMBLNCOP_02305 7.4e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NMBLNCOP_02306 2.3e-09
NMBLNCOP_02307 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NMBLNCOP_02308 2.4e-89 stoA CO thiol-disulfide
NMBLNCOP_02309 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMBLNCOP_02310 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
NMBLNCOP_02311 2.8e-28
NMBLNCOP_02312 6e-25 ykvS S protein conserved in bacteria
NMBLNCOP_02313 5.6e-46 ykvR S Protein of unknown function (DUF3219)
NMBLNCOP_02314 2.4e-162 G Glycosyl hydrolases family 18
NMBLNCOP_02315 3.5e-35 3.5.1.104 M LysM domain
NMBLNCOP_02316 4.4e-216 ykvP 3.5.1.28 M Glycosyl transferases group 1
NMBLNCOP_02317 5.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
NMBLNCOP_02318 3.8e-60 ykvN K HxlR-like helix-turn-helix
NMBLNCOP_02319 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NMBLNCOP_02320 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NMBLNCOP_02321 1.8e-80 queD 4.1.2.50, 4.2.3.12 H synthase
NMBLNCOP_02322 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NMBLNCOP_02323 1.4e-179 ykvI S membrane
NMBLNCOP_02324 0.0 clpE O Belongs to the ClpA ClpB family
NMBLNCOP_02325 1e-137 motA N flagellar motor
NMBLNCOP_02326 2.5e-125 motB N Flagellar motor protein
NMBLNCOP_02327 1.3e-75 ykvE K transcriptional
NMBLNCOP_02328 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NMBLNCOP_02329 2.6e-63 eag
NMBLNCOP_02330 6.4e-09 S Spo0E like sporulation regulatory protein
NMBLNCOP_02331 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
NMBLNCOP_02332 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NMBLNCOP_02333 8e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NMBLNCOP_02334 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NMBLNCOP_02335 3.4e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NMBLNCOP_02336 4e-231 mtnE 2.6.1.83 E Aminotransferase
NMBLNCOP_02337 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NMBLNCOP_02338 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NMBLNCOP_02339 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NMBLNCOP_02341 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NMBLNCOP_02342 0.0 kinE 2.7.13.3 T Histidine kinase
NMBLNCOP_02343 1.4e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NMBLNCOP_02344 1.4e-18 ykzE
NMBLNCOP_02345 1.2e-10 ydfR S Protein of unknown function (DUF421)
NMBLNCOP_02346 2.2e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
NMBLNCOP_02347 3.5e-155 htpX O Belongs to the peptidase M48B family
NMBLNCOP_02348 1.5e-124 ykrK S Domain of unknown function (DUF1836)
NMBLNCOP_02349 1.9e-26 sspD S small acid-soluble spore protein
NMBLNCOP_02350 3.1e-108 rsgI S Anti-sigma factor N-terminus
NMBLNCOP_02351 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMBLNCOP_02352 2.3e-173 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NMBLNCOP_02353 4e-116 ykoX S membrane-associated protein
NMBLNCOP_02354 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
NMBLNCOP_02355 1.2e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NMBLNCOP_02356 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NMBLNCOP_02357 6.2e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NMBLNCOP_02358 0.0 ykoS
NMBLNCOP_02359 2.1e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NMBLNCOP_02360 3.7e-99 ykoP G polysaccharide deacetylase
NMBLNCOP_02361 5.6e-219 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NMBLNCOP_02362 1.3e-81 mhqR K transcriptional
NMBLNCOP_02363 6.9e-26 ykoL
NMBLNCOP_02364 5.9e-18
NMBLNCOP_02365 1.4e-53 tnrA K transcriptional
NMBLNCOP_02366 2.2e-222 mgtE P Acts as a magnesium transporter
NMBLNCOP_02369 4.9e-85 ykoJ S Peptidase propeptide and YPEB domain
NMBLNCOP_02370 3.1e-111 ykoI S Peptidase propeptide and YPEB domain
NMBLNCOP_02371 2.4e-240 ykoH 2.7.13.3 T Histidine kinase
NMBLNCOP_02372 6.7e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMBLNCOP_02373 1.8e-110 ykoF S YKOF-related Family
NMBLNCOP_02374 2.6e-98 ykoE S ABC-type cobalt transport system, permease component
NMBLNCOP_02375 5.7e-305 P ABC transporter, ATP-binding protein
NMBLNCOP_02376 1.2e-135 ykoC P Cobalt transport protein
NMBLNCOP_02377 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMBLNCOP_02378 1.2e-174 isp O Belongs to the peptidase S8 family
NMBLNCOP_02379 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NMBLNCOP_02380 8.1e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NMBLNCOP_02381 8.4e-72 ohrB O Organic hydroperoxide resistance protein
NMBLNCOP_02382 4.4e-74 ohrR K COG1846 Transcriptional regulators
NMBLNCOP_02383 4.8e-70 ohrA O Organic hydroperoxide resistance protein
NMBLNCOP_02384 1.5e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NMBLNCOP_02385 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMBLNCOP_02386 7.3e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NMBLNCOP_02387 9.1e-50 ykkD P Multidrug resistance protein
NMBLNCOP_02388 1.7e-54 ykkC P Multidrug resistance protein
NMBLNCOP_02389 2.4e-95 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMBLNCOP_02390 1.3e-96 ykkA S Protein of unknown function (DUF664)
NMBLNCOP_02391 3.9e-128 ykjA S Protein of unknown function (DUF421)
NMBLNCOP_02392 1.5e-09
NMBLNCOP_02393 2.8e-224 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NMBLNCOP_02394 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NMBLNCOP_02395 6.5e-159 ykgA E Amidinotransferase
NMBLNCOP_02396 9e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
NMBLNCOP_02397 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
NMBLNCOP_02398 1.2e-163 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NMBLNCOP_02399 2e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NMBLNCOP_02400 1.4e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NMBLNCOP_02402 0.0 dppE E ABC transporter substrate-binding protein
NMBLNCOP_02403 2.7e-188 dppD P Belongs to the ABC transporter superfamily
NMBLNCOP_02404 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMBLNCOP_02405 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMBLNCOP_02406 3.3e-152 dppA E D-aminopeptidase
NMBLNCOP_02407 5.3e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NMBLNCOP_02408 6.8e-211 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMBLNCOP_02410 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NMBLNCOP_02411 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NMBLNCOP_02412 6.7e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NMBLNCOP_02413 5.2e-240 steT E amino acid
NMBLNCOP_02414 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NMBLNCOP_02415 5.8e-175 pit P phosphate transporter
NMBLNCOP_02416 1.1e-135 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NMBLNCOP_02417 6.7e-23 spoIISB S Stage II sporulation protein SB
NMBLNCOP_02418 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMBLNCOP_02419 6e-39 xhlB S SPP1 phage holin
NMBLNCOP_02420 2.8e-39 xhlA S Haemolysin XhlA
NMBLNCOP_02421 1.2e-154 xepA
NMBLNCOP_02422 1.4e-22 xkdX
NMBLNCOP_02423 2.6e-55 xkdW S XkdW protein
NMBLNCOP_02424 5e-261
NMBLNCOP_02425 6.7e-41
NMBLNCOP_02426 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NMBLNCOP_02427 1.6e-188 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NMBLNCOP_02428 1.8e-69 xkdS S Protein of unknown function (DUF2634)
NMBLNCOP_02429 4.7e-39 xkdR S Protein of unknown function (DUF2577)
NMBLNCOP_02430 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
NMBLNCOP_02431 3.7e-122 xkdP S Lysin motif
NMBLNCOP_02432 0.0 xkdO L Transglycosylase SLT domain
NMBLNCOP_02433 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
NMBLNCOP_02434 6.1e-76 xkdM S Phage tail tube protein
NMBLNCOP_02435 3.2e-256 xkdK S Phage tail sheath C-terminal domain
NMBLNCOP_02436 1.9e-77 xkdJ
NMBLNCOP_02437 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
NMBLNCOP_02438 8.7e-65 yqbH S Domain of unknown function (DUF3599)
NMBLNCOP_02439 7.4e-62 yqbG S Protein of unknown function (DUF3199)
NMBLNCOP_02440 1.7e-168 xkdG S Phage capsid family
NMBLNCOP_02441 7.7e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NMBLNCOP_02442 1.6e-285 yqbA S portal protein
NMBLNCOP_02443 1.4e-253 xtmB S phage terminase, large subunit
NMBLNCOP_02444 5.3e-139 xtmA L phage terminase small subunit
NMBLNCOP_02445 4.5e-83 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NMBLNCOP_02446 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
NMBLNCOP_02449 4.1e-118 xkdC L Bacterial dnaA protein
NMBLNCOP_02450 2.5e-155 xkdB K sequence-specific DNA binding
NMBLNCOP_02452 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
NMBLNCOP_02453 1.6e-111 xkdA E IrrE N-terminal-like domain
NMBLNCOP_02454 4.4e-160 ydbD P Catalase
NMBLNCOP_02455 1.8e-110 yjqB S Pfam:DUF867
NMBLNCOP_02456 6.8e-60 yjqA S Bacterial PH domain
NMBLNCOP_02457 1.4e-165 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NMBLNCOP_02458 6.3e-41 S YCII-related domain
NMBLNCOP_02460 1e-212 S response regulator aspartate phosphatase
NMBLNCOP_02461 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NMBLNCOP_02462 2.3e-78 yjoA S DinB family
NMBLNCOP_02463 4.3e-130 MA20_18170 S membrane transporter protein
NMBLNCOP_02464 3.3e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NMBLNCOP_02465 3.5e-282 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NMBLNCOP_02466 6.8e-184 exuR K transcriptional
NMBLNCOP_02467 3.7e-227 exuT G Sugar (and other) transporter
NMBLNCOP_02468 5.8e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMBLNCOP_02469 2.3e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NMBLNCOP_02470 9.4e-189 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NMBLNCOP_02471 8.1e-193 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NMBLNCOP_02472 5.8e-250 yjmB G symporter YjmB
NMBLNCOP_02473 2.7e-279 uxaC 5.3.1.12 G glucuronate isomerase
NMBLNCOP_02474 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
NMBLNCOP_02475 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NMBLNCOP_02476 1.7e-90 yjlB S Cupin domain
NMBLNCOP_02477 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
NMBLNCOP_02478 2.9e-134 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NMBLNCOP_02479 7.3e-122 ybbM S transport system, permease component
NMBLNCOP_02480 9.6e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NMBLNCOP_02481 8.2e-30
NMBLNCOP_02482 3.2e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NMBLNCOP_02483 8.9e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NMBLNCOP_02485 2.1e-114 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NMBLNCOP_02486 1.6e-10 S Domain of unknown function (DUF4352)
NMBLNCOP_02487 1.5e-92 yjgD S Protein of unknown function (DUF1641)
NMBLNCOP_02488 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NMBLNCOP_02489 4.4e-103 yjgB S Domain of unknown function (DUF4309)
NMBLNCOP_02490 4.9e-34 T PhoQ Sensor
NMBLNCOP_02491 2.1e-148 yjfC O Predicted Zn-dependent protease (DUF2268)
NMBLNCOP_02492 2.3e-20 yjfB S Putative motility protein
NMBLNCOP_02493 5.1e-81 S Protein of unknown function (DUF2690)
NMBLNCOP_02494 5.5e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
NMBLNCOP_02496 1.2e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NMBLNCOP_02497 1.7e-51 yjdJ S Domain of unknown function (DUF4306)
NMBLNCOP_02498 7.1e-29 S Domain of unknown function (DUF4177)
NMBLNCOP_02499 2.2e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NMBLNCOP_02501 5.3e-92 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NMBLNCOP_02502 3e-45 yjdF S Protein of unknown function (DUF2992)
NMBLNCOP_02503 2.6e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
NMBLNCOP_02504 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NMBLNCOP_02505 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NMBLNCOP_02506 1e-45 yjcN
NMBLNCOP_02507 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
NMBLNCOP_02508 4.1e-180 S response regulator aspartate phosphatase
NMBLNCOP_02511 8.3e-21
NMBLNCOP_02512 1.9e-248 M nucleic acid phosphodiester bond hydrolysis
NMBLNCOP_02513 1.1e-30
NMBLNCOP_02514 6.7e-18
NMBLNCOP_02516 9.5e-209 yjcL S Protein of unknown function (DUF819)
NMBLNCOP_02517 2.5e-95 rimJ 2.3.1.128 J Alanine acetyltransferase
NMBLNCOP_02518 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NMBLNCOP_02519 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NMBLNCOP_02520 5.9e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
NMBLNCOP_02521 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NMBLNCOP_02522 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMBLNCOP_02523 1.7e-38
NMBLNCOP_02524 0.0 yjcD 3.6.4.12 L DNA helicase
NMBLNCOP_02525 2.9e-38 spoVIF S Stage VI sporulation protein F
NMBLNCOP_02528 4.3e-56 yjcA S Protein of unknown function (DUF1360)
NMBLNCOP_02529 2.3e-55 cotV S Spore Coat Protein X and V domain
NMBLNCOP_02530 8.5e-32 cotW
NMBLNCOP_02531 6.4e-77 cotX S Spore Coat Protein X and V domain
NMBLNCOP_02532 3.4e-96 cotY S Spore coat protein Z
NMBLNCOP_02533 5.2e-83 cotZ S Spore coat protein
NMBLNCOP_02534 5.9e-54 yjbX S Spore coat protein
NMBLNCOP_02535 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NMBLNCOP_02536 5.8e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NMBLNCOP_02537 1.9e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NMBLNCOP_02538 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NMBLNCOP_02539 4.8e-28 thiS H thiamine diphosphate biosynthetic process
NMBLNCOP_02540 3.4e-216 thiO 1.4.3.19 E Glycine oxidase
NMBLNCOP_02541 2.7e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NMBLNCOP_02542 7.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NMBLNCOP_02543 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NMBLNCOP_02544 1.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NMBLNCOP_02545 5.2e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMBLNCOP_02546 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMBLNCOP_02547 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NMBLNCOP_02548 7.1e-62 yjbL S Belongs to the UPF0738 family
NMBLNCOP_02549 4.1e-101 yjbK S protein conserved in bacteria
NMBLNCOP_02550 9.7e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NMBLNCOP_02551 3.7e-72 yjbI S Bacterial-like globin
NMBLNCOP_02552 8e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NMBLNCOP_02553 1.8e-20
NMBLNCOP_02554 0.0 pepF E oligoendopeptidase F
NMBLNCOP_02555 1.2e-219 yjbF S Competence protein
NMBLNCOP_02556 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NMBLNCOP_02557 2.3e-111 yjbE P Integral membrane protein TerC family
NMBLNCOP_02558 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NMBLNCOP_02559 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMBLNCOP_02560 8.3e-211 yjbB EGP Major Facilitator Superfamily
NMBLNCOP_02561 5.5e-172 oppF E Belongs to the ABC transporter superfamily
NMBLNCOP_02562 3.4e-197 oppD P Belongs to the ABC transporter superfamily
NMBLNCOP_02563 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMBLNCOP_02564 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMBLNCOP_02565 0.0 oppA E ABC transporter substrate-binding protein
NMBLNCOP_02566 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NMBLNCOP_02567 5e-147 yjbA S Belongs to the UPF0736 family
NMBLNCOP_02568 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMBLNCOP_02569 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMBLNCOP_02570 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NMBLNCOP_02571 4.2e-186 appF E Belongs to the ABC transporter superfamily
NMBLNCOP_02572 1.8e-184 appD P Belongs to the ABC transporter superfamily
NMBLNCOP_02573 1.2e-148 yjaZ O Zn-dependent protease
NMBLNCOP_02574 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NMBLNCOP_02575 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMBLNCOP_02576 5e-21 yjzB
NMBLNCOP_02577 7.3e-26 comZ S ComZ
NMBLNCOP_02578 2.5e-183 med S Transcriptional activator protein med
NMBLNCOP_02579 5.8e-100 yjaV
NMBLNCOP_02580 2.4e-141 yjaU I carboxylic ester hydrolase activity
NMBLNCOP_02581 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NMBLNCOP_02582 9.5e-28 yjzC S YjzC-like protein
NMBLNCOP_02583 7.2e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NMBLNCOP_02584 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NMBLNCOP_02585 1.5e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NMBLNCOP_02586 4.6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NMBLNCOP_02587 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NMBLNCOP_02588 2e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NMBLNCOP_02589 2.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NMBLNCOP_02590 1.7e-88 norB G Major Facilitator Superfamily
NMBLNCOP_02591 2.4e-267 yitY C D-arabinono-1,4-lactone oxidase
NMBLNCOP_02592 1.5e-22 pilT S Proteolipid membrane potential modulator
NMBLNCOP_02593 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NMBLNCOP_02594 1e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NMBLNCOP_02595 5.4e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NMBLNCOP_02597 1.2e-17 S Protein of unknown function (DUF3813)
NMBLNCOP_02598 3.8e-73 ipi S Intracellular proteinase inhibitor
NMBLNCOP_02599 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NMBLNCOP_02600 2.5e-158 yitS S protein conserved in bacteria
NMBLNCOP_02601 7.1e-308 nprB 3.4.24.28 E Peptidase M4
NMBLNCOP_02602 1.4e-44 yitR S Domain of unknown function (DUF3784)
NMBLNCOP_02603 7.3e-93
NMBLNCOP_02604 4.5e-58 K Transcriptional regulator PadR-like family
NMBLNCOP_02605 1.5e-97 S Sporulation delaying protein SdpA
NMBLNCOP_02606 2.8e-171
NMBLNCOP_02607 3.2e-93
NMBLNCOP_02608 1.1e-158 cvfB S protein conserved in bacteria
NMBLNCOP_02609 5.6e-54 yajQ S Belongs to the UPF0234 family
NMBLNCOP_02610 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NMBLNCOP_02611 1e-70 yjcF S Acetyltransferase (GNAT) domain
NMBLNCOP_02612 1.1e-147 yitH K Acetyltransferase (GNAT) domain
NMBLNCOP_02613 1.5e-228 yitG EGP Major facilitator Superfamily
NMBLNCOP_02614 7.8e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NMBLNCOP_02615 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMBLNCOP_02616 1.6e-140 yitD 4.4.1.19 S synthase
NMBLNCOP_02617 4e-119 comB 3.1.3.71 H Belongs to the ComB family
NMBLNCOP_02618 3.9e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NMBLNCOP_02619 2.5e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NMBLNCOP_02620 4.2e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NMBLNCOP_02621 7.7e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMBLNCOP_02622 1.2e-35 mcbG S Pentapeptide repeats (9 copies)
NMBLNCOP_02623 5.3e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMBLNCOP_02624 1.1e-104 argO S Lysine exporter protein LysE YggA
NMBLNCOP_02625 5.3e-92 yisT S DinB family
NMBLNCOP_02626 1.3e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NMBLNCOP_02627 2.4e-184 purR K helix_turn _helix lactose operon repressor
NMBLNCOP_02628 2.7e-160 yisR K Transcriptional regulator
NMBLNCOP_02629 1.5e-242 yisQ V Mate efflux family protein
NMBLNCOP_02630 8.3e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NMBLNCOP_02631 3.9e-87 yizA S Damage-inducible protein DinB
NMBLNCOP_02632 0.0 asnO 6.3.5.4 E Asparagine synthase
NMBLNCOP_02633 5.4e-98 yisN S Protein of unknown function (DUF2777)
NMBLNCOP_02634 0.0 wprA O Belongs to the peptidase S8 family
NMBLNCOP_02635 3e-57 yisL S UPF0344 protein
NMBLNCOP_02636 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NMBLNCOP_02637 9.1e-175 cotH M Spore Coat
NMBLNCOP_02638 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NMBLNCOP_02639 1.9e-33 gerPA S Spore germination protein
NMBLNCOP_02640 4e-34 gerPB S cell differentiation
NMBLNCOP_02641 5.3e-54 gerPC S Spore germination protein
NMBLNCOP_02642 1.1e-23 gerPD S Spore germination protein
NMBLNCOP_02643 5.3e-63 gerPE S Spore germination protein GerPE
NMBLNCOP_02644 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NMBLNCOP_02645 1.1e-49 yisB V COG1403 Restriction endonuclease
NMBLNCOP_02646 0.0 sbcC L COG0419 ATPase involved in DNA repair
NMBLNCOP_02647 2e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NMBLNCOP_02648 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NMBLNCOP_02649 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NMBLNCOP_02650 6.4e-78 yhjR S Rubrerythrin
NMBLNCOP_02651 5.9e-36 yhjQ C COG1145 Ferredoxin
NMBLNCOP_02652 0.0 S Sugar transport-related sRNA regulator N-term
NMBLNCOP_02653 3.5e-211 EGP Transmembrane secretion effector
NMBLNCOP_02654 1.9e-201 abrB S membrane
NMBLNCOP_02655 6.5e-187 yhjM 5.1.1.1 K Transcriptional regulator
NMBLNCOP_02656 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NMBLNCOP_02657 4e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NMBLNCOP_02658 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NMBLNCOP_02659 2.5e-212 glcP G Major Facilitator Superfamily
NMBLNCOP_02662 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
NMBLNCOP_02663 4.5e-280 yhjG CH FAD binding domain
NMBLNCOP_02664 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NMBLNCOP_02665 9.1e-110 yhjE S SNARE associated Golgi protein
NMBLNCOP_02666 6.7e-60 yhjD
NMBLNCOP_02667 2.9e-15 yhjC S Protein of unknown function (DUF3311)
NMBLNCOP_02668 1.2e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMBLNCOP_02669 2.3e-38 yhjA S Excalibur calcium-binding domain
NMBLNCOP_02670 4.7e-168 IQ Enoyl-(Acyl carrier protein) reductase
NMBLNCOP_02671 4.2e-109 comK K Competence transcription factor
NMBLNCOP_02672 1.3e-32 yhzC S IDEAL
NMBLNCOP_02673 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMBLNCOP_02674 7.5e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NMBLNCOP_02675 2e-180 hemAT NT chemotaxis protein
NMBLNCOP_02676 5e-91 bioY S BioY family
NMBLNCOP_02677 3.9e-273 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NMBLNCOP_02678 1.7e-196 vraB 2.3.1.9 I Belongs to the thiolase family
NMBLNCOP_02679 5.5e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NMBLNCOP_02680 4.3e-159 yfmC M Periplasmic binding protein
NMBLNCOP_02681 3.1e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
NMBLNCOP_02682 3.6e-76 VY92_01935 K acetyltransferase
NMBLNCOP_02683 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NMBLNCOP_02684 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
NMBLNCOP_02685 1.4e-63 yhfM
NMBLNCOP_02686 1.6e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NMBLNCOP_02687 2.2e-111 yhfK GM NmrA-like family
NMBLNCOP_02688 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
NMBLNCOP_02689 1.5e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NMBLNCOP_02690 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMBLNCOP_02691 1.1e-71 3.4.13.21 S ASCH
NMBLNCOP_02692 2.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NMBLNCOP_02693 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
NMBLNCOP_02694 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMBLNCOP_02695 1.6e-228 yhgE S YhgE Pip N-terminal domain protein
NMBLNCOP_02696 5.4e-101 yhgD K Transcriptional regulator
NMBLNCOP_02697 5e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NMBLNCOP_02698 8.9e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NMBLNCOP_02699 7e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NMBLNCOP_02700 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NMBLNCOP_02701 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NMBLNCOP_02702 1.1e-33 1.15.1.2 C Rubrerythrin
NMBLNCOP_02703 1.1e-243 yhfA C membrane
NMBLNCOP_02704 5.7e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NMBLNCOP_02705 3.1e-114 ecsC S EcsC protein family
NMBLNCOP_02706 5.9e-214 ecsB U ABC transporter
NMBLNCOP_02707 8.8e-136 ecsA V transporter (ATP-binding protein)
NMBLNCOP_02708 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NMBLNCOP_02709 1.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NMBLNCOP_02710 3.6e-80 trpP S Tryptophan transporter TrpP
NMBLNCOP_02711 1.2e-20
NMBLNCOP_02712 5.4e-39 yhaH S YtxH-like protein
NMBLNCOP_02713 2.3e-113 hpr K Negative regulator of protease production and sporulation
NMBLNCOP_02714 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NMBLNCOP_02715 8.7e-90 yhaK S Putative zincin peptidase
NMBLNCOP_02716 3.2e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NMBLNCOP_02717 1.6e-21 yhaL S Sporulation protein YhaL
NMBLNCOP_02718 7.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NMBLNCOP_02719 0.0 yhaN L AAA domain
NMBLNCOP_02720 8.2e-224 yhaO L DNA repair exonuclease
NMBLNCOP_02721 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NMBLNCOP_02722 8.9e-167 yhaQ S ABC transporter, ATP-binding protein
NMBLNCOP_02723 1.1e-26 S YhzD-like protein
NMBLNCOP_02724 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
NMBLNCOP_02726 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NMBLNCOP_02727 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NMBLNCOP_02728 1.8e-292 hemZ H coproporphyrinogen III oxidase
NMBLNCOP_02729 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NMBLNCOP_02730 1.6e-202 yhaZ L DNA alkylation repair enzyme
NMBLNCOP_02731 9.5e-48 yheA S Belongs to the UPF0342 family
NMBLNCOP_02732 2.2e-202 yheB S Belongs to the UPF0754 family
NMBLNCOP_02733 4.3e-216 yheC HJ YheC/D like ATP-grasp
NMBLNCOP_02734 1.5e-266 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NMBLNCOP_02735 1.4e-35 yheE S Family of unknown function (DUF5342)
NMBLNCOP_02736 6.3e-28 sspB S spore protein
NMBLNCOP_02737 7.6e-109 yheG GM NAD(P)H-binding
NMBLNCOP_02738 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMBLNCOP_02739 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMBLNCOP_02740 1.7e-83 nhaX T Belongs to the universal stress protein A family
NMBLNCOP_02741 4.3e-229 nhaC C Na H antiporter
NMBLNCOP_02742 6.9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NMBLNCOP_02743 6.3e-146 yheN G deacetylase
NMBLNCOP_02744 5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NMBLNCOP_02745 9.9e-184 yhdY M Mechanosensitive ion channel
NMBLNCOP_02747 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NMBLNCOP_02748 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMBLNCOP_02749 5.5e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMBLNCOP_02750 5.4e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NMBLNCOP_02751 8.8e-223 yhdR 2.6.1.1 E Aminotransferase
NMBLNCOP_02752 4.1e-74 cueR K transcriptional
NMBLNCOP_02753 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NMBLNCOP_02754 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NMBLNCOP_02755 3.1e-189 yhdN C Aldo keto reductase
NMBLNCOP_02756 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NMBLNCOP_02757 2.5e-200 yhdL S Sigma factor regulator N-terminal
NMBLNCOP_02758 8.1e-45 yhdK S Sigma-M inhibitor protein
NMBLNCOP_02759 1.6e-73 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMBLNCOP_02760 3.7e-268 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMBLNCOP_02761 5.7e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NMBLNCOP_02762 4.5e-250 yhdG E amino acid
NMBLNCOP_02763 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMBLNCOP_02764 1.2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
NMBLNCOP_02765 3.8e-162 citR K Transcriptional regulator
NMBLNCOP_02766 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NMBLNCOP_02767 2.4e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NMBLNCOP_02768 2.1e-276 ycgB S Stage V sporulation protein R
NMBLNCOP_02769 2.1e-237 ygxB M Conserved TM helix
NMBLNCOP_02770 1e-75 nsrR K Transcriptional regulator
NMBLNCOP_02771 7.6e-184 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NMBLNCOP_02772 4.8e-54 yhdC S Protein of unknown function (DUF3889)
NMBLNCOP_02773 1.2e-38 yhdB S YhdB-like protein
NMBLNCOP_02774 5.5e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
NMBLNCOP_02775 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMBLNCOP_02776 8.8e-212 yhcY 2.7.13.3 T Histidine kinase
NMBLNCOP_02777 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NMBLNCOP_02778 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NMBLNCOP_02779 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NMBLNCOP_02780 5.7e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NMBLNCOP_02781 9.9e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NMBLNCOP_02782 3e-259 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMBLNCOP_02783 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NMBLNCOP_02784 1e-119 yhcW 5.4.2.6 S hydrolase
NMBLNCOP_02785 9.9e-68 yhcV S COG0517 FOG CBS domain
NMBLNCOP_02786 9.3e-68 yhcU S Family of unknown function (DUF5365)
NMBLNCOP_02787 2.5e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMBLNCOP_02788 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NMBLNCOP_02789 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NMBLNCOP_02790 5.2e-100 yhcQ M Spore coat protein
NMBLNCOP_02791 6.2e-166 yhcP
NMBLNCOP_02792 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMBLNCOP_02793 4.9e-41 yhcM
NMBLNCOP_02794 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMBLNCOP_02795 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NMBLNCOP_02796 8.3e-151 metQ M Belongs to the nlpA lipoprotein family
NMBLNCOP_02797 1e-30 cspB K Cold-shock protein
NMBLNCOP_02798 8.7e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NMBLNCOP_02799 7.7e-166 yhcH V ABC transporter, ATP-binding protein
NMBLNCOP_02800 4e-122 yhcG V ABC transporter, ATP-binding protein
NMBLNCOP_02801 1.9e-59 yhcF K Transcriptional regulator
NMBLNCOP_02802 3.5e-55
NMBLNCOP_02803 2.8e-37 yhcC
NMBLNCOP_02804 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NMBLNCOP_02805 3.1e-271 yhcA EGP Major facilitator Superfamily
NMBLNCOP_02806 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NMBLNCOP_02807 2.2e-76 yhbI K DNA-binding transcription factor activity
NMBLNCOP_02808 2.5e-225 yhbH S Belongs to the UPF0229 family
NMBLNCOP_02809 0.0 prkA T Ser protein kinase
NMBLNCOP_02810 1.1e-68 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NMBLNCOP_02811 1.1e-58 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NMBLNCOP_02812 6e-109 yhbD K Protein of unknown function (DUF4004)
NMBLNCOP_02813 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NMBLNCOP_02814 4.8e-176 yhbB S Putative amidase domain
NMBLNCOP_02815 3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NMBLNCOP_02816 4.3e-112 yhzB S B3/4 domain
NMBLNCOP_02818 4.4e-29 K Transcriptional regulator
NMBLNCOP_02819 2.6e-77 ygaO
NMBLNCOP_02820 1.2e-39 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMBLNCOP_02822 9e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NMBLNCOP_02823 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NMBLNCOP_02824 4.3e-170 ssuA M Sulfonate ABC transporter
NMBLNCOP_02825 3.7e-137 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NMBLNCOP_02826 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NMBLNCOP_02828 1.9e-261 ygaK C Berberine and berberine like
NMBLNCOP_02829 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NMBLNCOP_02830 6.5e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NMBLNCOP_02831 1.2e-26
NMBLNCOP_02832 1.9e-141 spo0M S COG4326 Sporulation control protein
NMBLNCOP_02836 2e-08
NMBLNCOP_02844 7.8e-08
NMBLNCOP_02849 3.3e-23 S response regulator aspartate phosphatase
NMBLNCOP_02850 3.4e-39 S COG NOG14552 non supervised orthologous group
NMBLNCOP_02851 2.3e-85 wapA M COG3209 Rhs family protein
NMBLNCOP_02852 2.5e-166 ygxA S Nucleotidyltransferase-like
NMBLNCOP_02853 9.5e-56 ygzB S UPF0295 protein
NMBLNCOP_02854 4e-80 perR P Belongs to the Fur family
NMBLNCOP_02855 8.2e-87 bcp 1.11.1.15 O Peroxiredoxin
NMBLNCOP_02856 4.9e-243 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NMBLNCOP_02857 3.3e-179 ygaE S Membrane
NMBLNCOP_02858 1.8e-301 ygaD V ABC transporter
NMBLNCOP_02859 1.3e-104 ygaC J Belongs to the UPF0374 family
NMBLNCOP_02860 7.3e-37 ygaB S YgaB-like protein
NMBLNCOP_02861 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NMBLNCOP_02862 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMBLNCOP_02863 6.9e-36 yfhS
NMBLNCOP_02864 3.3e-210 mutY L A G-specific
NMBLNCOP_02865 1.2e-185 yfhP S membrane-bound metal-dependent
NMBLNCOP_02866 0.0 yfhO S Bacterial membrane protein YfhO
NMBLNCOP_02867 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NMBLNCOP_02868 1.3e-170 yfhM S Alpha beta hydrolase
NMBLNCOP_02869 3.9e-50 yfhL S SdpI/YhfL protein family
NMBLNCOP_02870 1e-90 batE T Bacterial SH3 domain homologues
NMBLNCOP_02871 1.3e-44 yfhJ S WVELL protein
NMBLNCOP_02872 6.2e-20 sspK S reproduction
NMBLNCOP_02873 2.5e-209 yfhI EGP Major facilitator Superfamily
NMBLNCOP_02875 1.7e-51 yfhH S Protein of unknown function (DUF1811)
NMBLNCOP_02876 5.7e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NMBLNCOP_02877 5.1e-170 yfhF S nucleoside-diphosphate sugar epimerase
NMBLNCOP_02879 2.1e-25 yfhD S YfhD-like protein
NMBLNCOP_02880 3.9e-107 yfhC C nitroreductase
NMBLNCOP_02881 1.5e-166 yfhB 5.3.3.17 S PhzF family
NMBLNCOP_02882 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMBLNCOP_02883 1.3e-174 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMBLNCOP_02884 3.5e-177 yfiY P ABC transporter substrate-binding protein
NMBLNCOP_02885 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NMBLNCOP_02886 4.9e-79 yfiV K transcriptional
NMBLNCOP_02887 1.1e-284 yfiU EGP Major facilitator Superfamily
NMBLNCOP_02888 4.4e-97 yfiT S Belongs to the metal hydrolase YfiT family
NMBLNCOP_02889 2.9e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NMBLNCOP_02890 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NMBLNCOP_02891 3.1e-98 padR K transcriptional
NMBLNCOP_02892 2.6e-203 V COG0842 ABC-type multidrug transport system, permease component
NMBLNCOP_02893 5.2e-207 V ABC-2 family transporter protein
NMBLNCOP_02894 9.2e-167 V ABC transporter, ATP-binding protein
NMBLNCOP_02895 1e-111 KT LuxR family transcriptional regulator
NMBLNCOP_02896 8.9e-212 yxjM T Histidine kinase
NMBLNCOP_02898 3.7e-162 yfiE 1.13.11.2 S glyoxalase
NMBLNCOP_02899 2.2e-64 mhqP S DoxX
NMBLNCOP_02900 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMBLNCOP_02901 1.4e-306 yfiB3 V ABC transporter
NMBLNCOP_02902 2.3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMBLNCOP_02903 4.6e-140 glvR K Helix-turn-helix domain, rpiR family
NMBLNCOP_02904 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NMBLNCOP_02905 3.3e-44 yfjA S Belongs to the WXG100 family
NMBLNCOP_02906 7.3e-172 yfjB
NMBLNCOP_02907 7.9e-124 yfjC
NMBLNCOP_02908 1.1e-85 S Family of unknown function (DUF5381)
NMBLNCOP_02909 4e-56 yfjF S UPF0060 membrane protein
NMBLNCOP_02910 1.2e-25 sspH S Belongs to the SspH family
NMBLNCOP_02911 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NMBLNCOP_02912 3.1e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NMBLNCOP_02913 3.7e-192 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMBLNCOP_02914 3.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMBLNCOP_02915 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NMBLNCOP_02916 1.7e-29 yfjL
NMBLNCOP_02917 9.6e-85 yfjM S Psort location Cytoplasmic, score
NMBLNCOP_02918 2.4e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMBLNCOP_02919 5.7e-43 S YfzA-like protein
NMBLNCOP_02920 5.3e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMBLNCOP_02921 8.5e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NMBLNCOP_02922 8.5e-184 corA P Mediates influx of magnesium ions
NMBLNCOP_02923 5.7e-69 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NMBLNCOP_02924 1.3e-51 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NMBLNCOP_02925 1.7e-153 pdaA G deacetylase
NMBLNCOP_02926 1.1e-26 yfjT
NMBLNCOP_02927 5.4e-222 yfkA S YfkB-like domain
NMBLNCOP_02928 6e-149 yfkC M Mechanosensitive ion channel
NMBLNCOP_02929 1.2e-146 yfkD S YfkD-like protein
NMBLNCOP_02930 6.1e-183 cax P COG0387 Ca2 H antiporter
NMBLNCOP_02931 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NMBLNCOP_02932 5e-08
NMBLNCOP_02933 1.3e-143 yihY S Belongs to the UPF0761 family
NMBLNCOP_02934 4.1e-50 yfkI S gas vesicle protein
NMBLNCOP_02935 1.4e-83 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMBLNCOP_02936 1.3e-28 yfkK S Belongs to the UPF0435 family
NMBLNCOP_02937 1.3e-205 ydiM EGP Major facilitator Superfamily
NMBLNCOP_02938 4.7e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
NMBLNCOP_02939 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NMBLNCOP_02940 1.1e-124 yfkO C nitroreductase
NMBLNCOP_02941 1.8e-133 treR K transcriptional
NMBLNCOP_02942 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NMBLNCOP_02943 1.5e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMBLNCOP_02944 2.2e-25 yfkQ EG Spore germination protein
NMBLNCOP_02945 2.2e-252 agcS_1 E Sodium alanine symporter
NMBLNCOP_02946 6e-67 yhdN S Domain of unknown function (DUF1992)
NMBLNCOP_02947 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMBLNCOP_02948 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NMBLNCOP_02949 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
NMBLNCOP_02950 5.3e-50 yflH S Protein of unknown function (DUF3243)
NMBLNCOP_02951 4.1e-19 yflI
NMBLNCOP_02952 4e-18 yflJ S Protein of unknown function (DUF2639)
NMBLNCOP_02953 8.4e-122 yflK S protein conserved in bacteria
NMBLNCOP_02954 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NMBLNCOP_02955 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NMBLNCOP_02956 2.1e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NMBLNCOP_02957 1.2e-225 citM C Citrate transporter
NMBLNCOP_02958 6.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
NMBLNCOP_02959 2.4e-116 citT T response regulator
NMBLNCOP_02960 4.1e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NMBLNCOP_02961 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
NMBLNCOP_02962 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NMBLNCOP_02963 7.6e-58 yflT S Heat induced stress protein YflT
NMBLNCOP_02964 2.6e-24 S Protein of unknown function (DUF3212)
NMBLNCOP_02965 1.2e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NMBLNCOP_02966 6.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMBLNCOP_02967 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMBLNCOP_02968 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NMBLNCOP_02969 9.7e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
NMBLNCOP_02970 2.2e-213 G Major Facilitator Superfamily
NMBLNCOP_02971 6.7e-187 yfmJ S N-terminal domain of oxidoreductase
NMBLNCOP_02972 1e-75 yfmK 2.3.1.128 K acetyltransferase
NMBLNCOP_02973 1.4e-198 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NMBLNCOP_02974 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NMBLNCOP_02975 2.5e-36
NMBLNCOP_02976 1.2e-208 yfmO EGP Major facilitator Superfamily
NMBLNCOP_02977 2.4e-69 yfmP K transcriptional
NMBLNCOP_02978 1.2e-68 yfmQ S Uncharacterised protein from bacillus cereus group
NMBLNCOP_02979 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NMBLNCOP_02980 1.1e-113 yfmS NT chemotaxis protein
NMBLNCOP_02981 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMBLNCOP_02982 1.4e-240 yfnA E amino acid
NMBLNCOP_02983 2.5e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NMBLNCOP_02984 1.7e-205 fsr P COG0477 Permeases of the major facilitator superfamily
NMBLNCOP_02985 1.9e-188 yfnD M Nucleotide-diphospho-sugar transferase
NMBLNCOP_02986 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NMBLNCOP_02987 1.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
NMBLNCOP_02988 1.9e-172 yfnG 4.2.1.45 M dehydratase
NMBLNCOP_02989 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
NMBLNCOP_02990 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMBLNCOP_02991 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NMBLNCOP_02992 2.3e-198 yetN S Protein of unknown function (DUF3900)
NMBLNCOP_02993 3e-29 yetM CH FAD binding domain
NMBLNCOP_02994 2e-08 yetL K helix_turn_helix multiple antibiotic resistance protein
NMBLNCOP_02995 5.3e-105 yetJ S Belongs to the BI1 family
NMBLNCOP_02996 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
NMBLNCOP_02997 4.2e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMBLNCOP_02998 2.2e-34
NMBLNCOP_02999 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMBLNCOP_03000 8.2e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NMBLNCOP_03001 4e-122 yetF S membrane
NMBLNCOP_03002 2.1e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NMBLNCOP_03003 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
NMBLNCOP_03004 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NMBLNCOP_03005 9e-289 lplA G Bacterial extracellular solute-binding protein
NMBLNCOP_03006 0.0 yetA
NMBLNCOP_03007 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NMBLNCOP_03008 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
NMBLNCOP_03009 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NMBLNCOP_03010 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NMBLNCOP_03011 9.7e-112 yesV S Protein of unknown function, DUF624
NMBLNCOP_03012 7.8e-128 yesU S Domain of unknown function (DUF1961)
NMBLNCOP_03013 2.5e-132 E GDSL-like Lipase/Acylhydrolase
NMBLNCOP_03014 0.0 yesS K Transcriptional regulator
NMBLNCOP_03015 1e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NMBLNCOP_03016 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
NMBLNCOP_03017 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
NMBLNCOP_03018 1.5e-247 yesO G Bacterial extracellular solute-binding protein
NMBLNCOP_03019 1.8e-201 yesN K helix_turn_helix, arabinose operon control protein
NMBLNCOP_03020 0.0 yesM 2.7.13.3 T Histidine kinase
NMBLNCOP_03021 3.4e-101 yesL S Protein of unknown function, DUF624
NMBLNCOP_03022 6e-102 yesJ K Acetyltransferase (GNAT) family
NMBLNCOP_03023 5.2e-104 cotJC P Spore Coat
NMBLNCOP_03024 1.5e-45 cotJB S CotJB protein
NMBLNCOP_03025 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NMBLNCOP_03026 3.7e-146 yesF GM NAD(P)H-binding
NMBLNCOP_03027 1.8e-80 yesE S SnoaL-like domain
NMBLNCOP_03028 3.6e-100 dhaR3 K Transcriptional regulator
NMBLNCOP_03030 9.4e-127 yeeN K transcriptional regulatory protein
NMBLNCOP_03032 7.9e-213 S Tetratricopeptide repeat
NMBLNCOP_03033 5.7e-15 S Lysozyme inhibitor LprI
NMBLNCOP_03034 1e-49
NMBLNCOP_03035 7.3e-100 L endonuclease activity
NMBLNCOP_03037 2.7e-183 L nucleic acid phosphodiester bond hydrolysis
NMBLNCOP_03038 1.2e-22
NMBLNCOP_03039 1.1e-73 V Abc transporter
NMBLNCOP_03042 2.4e-54
NMBLNCOP_03043 3.7e-13
NMBLNCOP_03044 5.8e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMBLNCOP_03045 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NMBLNCOP_03046 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NMBLNCOP_03047 5.9e-144 yerO K Transcriptional regulator
NMBLNCOP_03048 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMBLNCOP_03049 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NMBLNCOP_03050 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMBLNCOP_03051 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMBLNCOP_03052 6.1e-123 sapB S MgtC SapB transporter
NMBLNCOP_03053 2e-196 yerI S homoserine kinase type II (protein kinase fold)
NMBLNCOP_03054 7e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
NMBLNCOP_03055 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NMBLNCOP_03056 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NMBLNCOP_03057 1.4e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NMBLNCOP_03059 5.3e-300 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NMBLNCOP_03060 2.4e-50 yerC S protein conserved in bacteria
NMBLNCOP_03061 3.7e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
NMBLNCOP_03062 0.0 yerA 3.5.4.2 F adenine deaminase
NMBLNCOP_03063 1.6e-27 S Protein of unknown function (DUF2892)
NMBLNCOP_03064 6.1e-230 yjeH E Amino acid permease
NMBLNCOP_03065 1e-72 K helix_turn_helix ASNC type
NMBLNCOP_03066 5.9e-233 purD 6.3.4.13 F Belongs to the GARS family
NMBLNCOP_03067 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NMBLNCOP_03068 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NMBLNCOP_03069 1.4e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NMBLNCOP_03070 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NMBLNCOP_03071 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMBLNCOP_03072 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMBLNCOP_03073 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMBLNCOP_03074 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NMBLNCOP_03075 8.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NMBLNCOP_03076 1.3e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NMBLNCOP_03077 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NMBLNCOP_03078 8e-28 yebG S NETI protein
NMBLNCOP_03079 8.9e-93 yebE S UPF0316 protein
NMBLNCOP_03081 2.3e-118 yebC M Membrane
NMBLNCOP_03082 1e-211 pbuG S permease
NMBLNCOP_03083 6.1e-250 S Domain of unknown function (DUF4179)
NMBLNCOP_03084 6.6e-85 K Belongs to the sigma-70 factor family. ECF subfamily
NMBLNCOP_03085 1.2e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NMBLNCOP_03086 0.0 yebA E COG1305 Transglutaminase-like enzymes
NMBLNCOP_03087 9.9e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NMBLNCOP_03088 3.9e-176 yeaC S COG0714 MoxR-like ATPases
NMBLNCOP_03089 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMBLNCOP_03090 4.4e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NMBLNCOP_03091 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NMBLNCOP_03092 2.9e-179 yeaA S Protein of unknown function (DUF4003)
NMBLNCOP_03093 6.8e-158 ydjP I Alpha/beta hydrolase family
NMBLNCOP_03094 1.2e-34 ydjO S Cold-inducible protein YdjO
NMBLNCOP_03096 3.1e-155 ydjN U Involved in the tonB-independent uptake of proteins
NMBLNCOP_03097 4.5e-64 ydjM M Lytic transglycolase
NMBLNCOP_03098 2e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NMBLNCOP_03099 3.9e-257 iolT EGP Major facilitator Superfamily
NMBLNCOP_03100 4.7e-196 S Ion transport 2 domain protein
NMBLNCOP_03101 2e-148 ydjI S virion core protein (lumpy skin disease virus)
NMBLNCOP_03102 5.1e-131 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NMBLNCOP_03103 7.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMBLNCOP_03104 8.7e-114 pspA KT Phage shock protein A
NMBLNCOP_03105 3.6e-174 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NMBLNCOP_03106 5.6e-253 gutA G MFS/sugar transport protein
NMBLNCOP_03107 3.2e-200 gutB 1.1.1.14 E Dehydrogenase
NMBLNCOP_03108 0.0 K NB-ARC domain
NMBLNCOP_03109 8.9e-152 ydjC S Abhydrolase domain containing 18
NMBLNCOP_03110 2.6e-177 V Restriction endonuclease
NMBLNCOP_03111 2.9e-68 2.7.7.49 L DNA polymerase
NMBLNCOP_03112 1.5e-37
NMBLNCOP_03113 9.4e-37 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
NMBLNCOP_03114 3.6e-25 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
NMBLNCOP_03115 5.3e-50 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
NMBLNCOP_03116 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NMBLNCOP_03117 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NMBLNCOP_03118 7.9e-129 ydiL S CAAX protease self-immunity
NMBLNCOP_03119 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NMBLNCOP_03120 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NMBLNCOP_03121 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NMBLNCOP_03122 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NMBLNCOP_03123 7.2e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NMBLNCOP_03124 0.0 ydiF S ABC transporter
NMBLNCOP_03125 5.2e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NMBLNCOP_03126 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NMBLNCOP_03127 2.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NMBLNCOP_03128 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NMBLNCOP_03129 1e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NMBLNCOP_03131 7.8e-08
NMBLNCOP_03132 1.1e-10 S Histidine kinase
NMBLNCOP_03135 6.3e-89 thiT S Thiamine transporter protein (Thia_YuaJ)
NMBLNCOP_03136 1.6e-91 M1-753 M FR47-like protein
NMBLNCOP_03137 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
NMBLNCOP_03138 9.4e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NMBLNCOP_03139 3.9e-84 yuaE S DinB superfamily
NMBLNCOP_03140 3.7e-105 yuaD
NMBLNCOP_03141 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
NMBLNCOP_03142 5.2e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NMBLNCOP_03143 5.5e-95 yuaC K Belongs to the GbsR family
NMBLNCOP_03144 2.2e-91 yuaB
NMBLNCOP_03145 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
NMBLNCOP_03146 1.6e-236 ktrB P Potassium
NMBLNCOP_03147 1e-38 yiaA S yiaA/B two helix domain
NMBLNCOP_03148 3.2e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NMBLNCOP_03149 1.9e-273 yubD P Major Facilitator Superfamily
NMBLNCOP_03150 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NMBLNCOP_03152 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NMBLNCOP_03153 3.7e-189 yubA S transporter activity
NMBLNCOP_03154 9.7e-183 ygjR S Oxidoreductase
NMBLNCOP_03155 3.3e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NMBLNCOP_03156 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NMBLNCOP_03157 6.7e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NMBLNCOP_03158 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NMBLNCOP_03159 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NMBLNCOP_03160 7.3e-238 mcpA NT chemotaxis protein
NMBLNCOP_03161 5.5e-294 mcpA NT chemotaxis protein
NMBLNCOP_03162 3.1e-220 mcpA NT chemotaxis protein
NMBLNCOP_03163 6e-224 mcpA NT chemotaxis protein
NMBLNCOP_03164 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NMBLNCOP_03165 1e-35
NMBLNCOP_03166 2.4e-71 yugU S Uncharacterised protein family UPF0047
NMBLNCOP_03167 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NMBLNCOP_03168 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NMBLNCOP_03169 1.4e-116 yugP S Zn-dependent protease
NMBLNCOP_03170 2.3e-38
NMBLNCOP_03171 5.9e-36 mstX S Membrane-integrating protein Mistic
NMBLNCOP_03172 1.1e-181 yugO P COG1226 Kef-type K transport systems
NMBLNCOP_03173 6.3e-72 yugN S YugN-like family
NMBLNCOP_03175 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NMBLNCOP_03176 5.3e-228 yugK C Dehydrogenase
NMBLNCOP_03177 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NMBLNCOP_03178 4e-34 yuzA S Domain of unknown function (DUF378)
NMBLNCOP_03179 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NMBLNCOP_03180 2.1e-199 yugH 2.6.1.1 E Aminotransferase
NMBLNCOP_03181 1.6e-85 alaR K Transcriptional regulator
NMBLNCOP_03182 1.4e-155 yugF I Hydrolase
NMBLNCOP_03183 4.6e-39 yugE S Domain of unknown function (DUF1871)
NMBLNCOP_03184 5.8e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NMBLNCOP_03185 4.6e-233 T PhoQ Sensor
NMBLNCOP_03186 4.8e-69 kapB G Kinase associated protein B
NMBLNCOP_03187 4.2e-115 kapD L the KinA pathway to sporulation
NMBLNCOP_03189 4.2e-184 yuxJ EGP Major facilitator Superfamily
NMBLNCOP_03190 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NMBLNCOP_03191 1.8e-74 yuxK S protein conserved in bacteria
NMBLNCOP_03192 6.3e-78 yufK S Family of unknown function (DUF5366)
NMBLNCOP_03193 6.4e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NMBLNCOP_03194 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
NMBLNCOP_03195 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NMBLNCOP_03196 2.7e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NMBLNCOP_03197 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
NMBLNCOP_03198 7.8e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
NMBLNCOP_03199 8.2e-233 maeN C COG3493 Na citrate symporter
NMBLNCOP_03200 5e-15
NMBLNCOP_03201 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NMBLNCOP_03202 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMBLNCOP_03203 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMBLNCOP_03204 2.1e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMBLNCOP_03205 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMBLNCOP_03206 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMBLNCOP_03207 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NMBLNCOP_03208 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
NMBLNCOP_03209 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMBLNCOP_03210 2.1e-276 comP 2.7.13.3 T Histidine kinase
NMBLNCOP_03212 8.9e-63 comQ H Belongs to the FPP GGPP synthase family
NMBLNCOP_03214 3.8e-23 yuzC
NMBLNCOP_03215 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NMBLNCOP_03216 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NMBLNCOP_03217 2.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
NMBLNCOP_03218 1.8e-66 yueI S Protein of unknown function (DUF1694)
NMBLNCOP_03219 2.8e-38 yueH S YueH-like protein
NMBLNCOP_03220 1.7e-31 yueG S Spore germination protein gerPA/gerPF
NMBLNCOP_03221 5.4e-190 yueF S transporter activity
NMBLNCOP_03222 3.2e-65 S Protein of unknown function (DUF2283)
NMBLNCOP_03223 2.9e-24 S Protein of unknown function (DUF2642)
NMBLNCOP_03224 1.8e-95 yueE S phosphohydrolase
NMBLNCOP_03225 4.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMBLNCOP_03226 3.3e-64 yueC S Family of unknown function (DUF5383)
NMBLNCOP_03227 0.0 esaA S type VII secretion protein EsaA
NMBLNCOP_03228 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NMBLNCOP_03229 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
NMBLNCOP_03230 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NMBLNCOP_03231 2.8e-45 esxA S Belongs to the WXG100 family
NMBLNCOP_03232 1.9e-228 yukF QT Transcriptional regulator
NMBLNCOP_03233 3e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NMBLNCOP_03234 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NMBLNCOP_03235 5e-36 mbtH S MbtH-like protein
NMBLNCOP_03236 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMBLNCOP_03237 4.4e-177 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NMBLNCOP_03238 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NMBLNCOP_03239 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
NMBLNCOP_03240 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMBLNCOP_03241 3.9e-167 besA S Putative esterase
NMBLNCOP_03242 1.7e-121 yuiH S Oxidoreductase molybdopterin binding domain
NMBLNCOP_03243 3.3e-93 bioY S Biotin biosynthesis protein
NMBLNCOP_03244 3.9e-211 yuiF S antiporter
NMBLNCOP_03245 1e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NMBLNCOP_03246 2e-77 yuiD S protein conserved in bacteria
NMBLNCOP_03247 4.7e-117 yuiC S protein conserved in bacteria
NMBLNCOP_03248 8.4e-27 yuiB S Putative membrane protein
NMBLNCOP_03249 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
NMBLNCOP_03250 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
NMBLNCOP_03252 6.7e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NMBLNCOP_03253 1.1e-115 paiB K Putative FMN-binding domain
NMBLNCOP_03254 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMBLNCOP_03255 3.7e-63 erpA S Belongs to the HesB IscA family
NMBLNCOP_03256 1.1e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NMBLNCOP_03257 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMBLNCOP_03258 3.2e-39 yuzB S Belongs to the UPF0349 family
NMBLNCOP_03259 7.7e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NMBLNCOP_03260 3.3e-55 yuzD S protein conserved in bacteria
NMBLNCOP_03261 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NMBLNCOP_03262 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NMBLNCOP_03263 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NMBLNCOP_03264 6.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NMBLNCOP_03265 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
NMBLNCOP_03266 5.9e-199 yutH S Spore coat protein
NMBLNCOP_03267 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NMBLNCOP_03268 2.5e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NMBLNCOP_03269 8.6e-75 yutE S Protein of unknown function DUF86
NMBLNCOP_03270 9.7e-48 yutD S protein conserved in bacteria
NMBLNCOP_03271 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMBLNCOP_03272 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NMBLNCOP_03273 1.3e-195 lytH M Peptidase, M23
NMBLNCOP_03274 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
NMBLNCOP_03275 3.1e-47 yunC S Domain of unknown function (DUF1805)
NMBLNCOP_03276 1.9e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NMBLNCOP_03277 1e-140 yunE S membrane transporter protein
NMBLNCOP_03278 1.3e-170 yunF S Protein of unknown function DUF72
NMBLNCOP_03279 1.4e-59 yunG
NMBLNCOP_03280 8.1e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NMBLNCOP_03281 2.4e-300 pucR QT COG2508 Regulator of polyketide synthase expression
NMBLNCOP_03282 4.7e-228 pbuX F Permease family
NMBLNCOP_03283 1.5e-220 pbuX F xanthine
NMBLNCOP_03284 4.4e-280 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NMBLNCOP_03285 5.1e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NMBLNCOP_03286 3.4e-94 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NMBLNCOP_03287 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NMBLNCOP_03288 5.2e-145 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NMBLNCOP_03289 2.4e-107 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NMBLNCOP_03290 3e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NMBLNCOP_03291 1.9e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NMBLNCOP_03292 2.2e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NMBLNCOP_03293 3.5e-168 bsn L Ribonuclease
NMBLNCOP_03294 5.9e-205 msmX P Belongs to the ABC transporter superfamily
NMBLNCOP_03295 1.6e-134 yurK K UTRA
NMBLNCOP_03296 4.8e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NMBLNCOP_03297 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
NMBLNCOP_03298 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
NMBLNCOP_03299 1.2e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NMBLNCOP_03300 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NMBLNCOP_03301 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NMBLNCOP_03302 3.8e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NMBLNCOP_03304 1e-41
NMBLNCOP_03305 6.6e-156
NMBLNCOP_03306 3.5e-271 sufB O FeS cluster assembly
NMBLNCOP_03307 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NMBLNCOP_03308 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NMBLNCOP_03309 1.4e-245 sufD O assembly protein SufD
NMBLNCOP_03310 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NMBLNCOP_03311 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NMBLNCOP_03312 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
NMBLNCOP_03313 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NMBLNCOP_03314 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NMBLNCOP_03315 2.4e-56 yusD S SCP-2 sterol transfer family
NMBLNCOP_03316 1.2e-54 traF CO Thioredoxin
NMBLNCOP_03317 4.8e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NMBLNCOP_03318 4.1e-39 yusG S Protein of unknown function (DUF2553)
NMBLNCOP_03319 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NMBLNCOP_03320 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NMBLNCOP_03321 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NMBLNCOP_03322 3.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
NMBLNCOP_03323 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NMBLNCOP_03324 8.1e-09 S YuzL-like protein
NMBLNCOP_03325 4.2e-164 fadM E Proline dehydrogenase
NMBLNCOP_03326 2.5e-39
NMBLNCOP_03327 5.4e-53 yusN M Coat F domain
NMBLNCOP_03328 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
NMBLNCOP_03329 3.2e-292 yusP P Major facilitator superfamily
NMBLNCOP_03330 6e-64 yusQ S Tautomerase enzyme
NMBLNCOP_03331 1e-104 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMBLNCOP_03332 5.7e-158 yusT K LysR substrate binding domain
NMBLNCOP_03333 3.3e-46 yusU S Protein of unknown function (DUF2573)
NMBLNCOP_03334 3.9e-153 yusV 3.6.3.34 HP ABC transporter
NMBLNCOP_03335 1.9e-66 S YusW-like protein
NMBLNCOP_03336 1.2e-300 pepF2 E COG1164 Oligoendopeptidase F
NMBLNCOP_03337 3.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMBLNCOP_03338 2.7e-79 dps P Ferritin-like domain
NMBLNCOP_03339 6.8e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMBLNCOP_03340 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMBLNCOP_03341 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
NMBLNCOP_03342 1.3e-157 yuxN K Transcriptional regulator
NMBLNCOP_03343 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NMBLNCOP_03344 3.9e-24 S Protein of unknown function (DUF3970)
NMBLNCOP_03345 7.2e-243 gerAA EG Spore germination protein
NMBLNCOP_03346 4e-193 gerAB E Spore germination protein
NMBLNCOP_03347 5.3e-185 gerAC S Spore germination B3/ GerAC like, C-terminal
NMBLNCOP_03348 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMBLNCOP_03349 7.9e-186 vraS 2.7.13.3 T Histidine kinase
NMBLNCOP_03350 3.6e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NMBLNCOP_03351 3.9e-119 liaG S Putative adhesin
NMBLNCOP_03352 9.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NMBLNCOP_03353 8.1e-61 liaI S membrane
NMBLNCOP_03354 4.8e-227 yvqJ EGP Major facilitator Superfamily
NMBLNCOP_03355 3.6e-100 yvqK 2.5.1.17 S Adenosyltransferase
NMBLNCOP_03356 1.5e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NMBLNCOP_03357 6.5e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMBLNCOP_03358 1.1e-167 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NMBLNCOP_03359 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMBLNCOP_03360 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
NMBLNCOP_03361 0.0 T PhoQ Sensor
NMBLNCOP_03362 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMBLNCOP_03363 3.6e-22
NMBLNCOP_03364 9.5e-98 yvrI K RNA polymerase
NMBLNCOP_03365 2.4e-19 S YvrJ protein family
NMBLNCOP_03366 1.8e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
NMBLNCOP_03367 1.3e-64 yvrL S Regulatory protein YrvL
NMBLNCOP_03368 7.5e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NMBLNCOP_03369 2.3e-122 macB V ABC transporter, ATP-binding protein
NMBLNCOP_03370 3.4e-174 M Efflux transporter rnd family, mfp subunit
NMBLNCOP_03371 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
NMBLNCOP_03372 1.2e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMBLNCOP_03373 2.3e-182 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMBLNCOP_03374 9e-178 fhuD P ABC transporter
NMBLNCOP_03375 4.9e-236 yvsH E Arginine ornithine antiporter
NMBLNCOP_03376 6.5e-16 S Small spore protein J (Spore_SspJ)
NMBLNCOP_03377 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NMBLNCOP_03378 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMBLNCOP_03379 3.2e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NMBLNCOP_03380 1.5e-133 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NMBLNCOP_03381 4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
NMBLNCOP_03382 1.1e-155 yvgN S reductase
NMBLNCOP_03383 2.1e-85 yvgO
NMBLNCOP_03384 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NMBLNCOP_03385 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NMBLNCOP_03386 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NMBLNCOP_03387 0.0 helD 3.6.4.12 L DNA helicase
NMBLNCOP_03388 4.1e-107 yvgT S membrane
NMBLNCOP_03389 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
NMBLNCOP_03390 1.6e-104 bdbD O Thioredoxin
NMBLNCOP_03391 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NMBLNCOP_03392 0.0 copA 3.6.3.54 P P-type ATPase
NMBLNCOP_03393 1.5e-29 copZ P Copper resistance protein CopZ
NMBLNCOP_03394 2.2e-48 csoR S transcriptional
NMBLNCOP_03395 8.4e-193 yvaA 1.1.1.371 S Oxidoreductase
NMBLNCOP_03396 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NMBLNCOP_03397 0.0 yvaC S Fusaric acid resistance protein-like
NMBLNCOP_03398 1.1e-71 yvaD S Family of unknown function (DUF5360)
NMBLNCOP_03399 1.8e-54 yvaE P Small Multidrug Resistance protein
NMBLNCOP_03400 3.3e-98 K Bacterial regulatory proteins, tetR family
NMBLNCOP_03401 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMBLNCOP_03403 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NMBLNCOP_03404 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NMBLNCOP_03405 5.6e-143 est 3.1.1.1 S Carboxylesterase
NMBLNCOP_03406 2.4e-23 secG U Preprotein translocase subunit SecG
NMBLNCOP_03407 3.7e-153 yvaM S Serine aminopeptidase, S33
NMBLNCOP_03408 7.5e-36 yvzC K Transcriptional
NMBLNCOP_03409 1.2e-68 K transcriptional
NMBLNCOP_03410 1.2e-68 yvaO K Cro/C1-type HTH DNA-binding domain
NMBLNCOP_03411 2.2e-54 yodB K transcriptional
NMBLNCOP_03412 1.9e-218 NT chemotaxis protein
NMBLNCOP_03413 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NMBLNCOP_03414 8e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NMBLNCOP_03415 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NMBLNCOP_03416 1.6e-208 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NMBLNCOP_03417 3.3e-60 yvbF K Belongs to the GbsR family
NMBLNCOP_03418 7.9e-13 S Sporulation delaying protein SdpA
NMBLNCOP_03419 7.6e-172
NMBLNCOP_03420 4.4e-08
NMBLNCOP_03421 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NMBLNCOP_03422 4.5e-45 sdpR K transcriptional
NMBLNCOP_03423 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NMBLNCOP_03424 6.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NMBLNCOP_03425 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NMBLNCOP_03426 2.6e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NMBLNCOP_03427 3.5e-97 yvbF K Belongs to the GbsR family
NMBLNCOP_03428 3.5e-101 yvbG U UPF0056 membrane protein
NMBLNCOP_03429 8.6e-113 yvbH S YvbH-like oligomerisation region
NMBLNCOP_03430 8e-123 exoY M Membrane
NMBLNCOP_03431 0.0 tcaA S response to antibiotic
NMBLNCOP_03432 1.8e-75 yvbK 3.1.3.25 K acetyltransferase
NMBLNCOP_03433 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NMBLNCOP_03434 6.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NMBLNCOP_03435 5.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NMBLNCOP_03436 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NMBLNCOP_03437 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NMBLNCOP_03438 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NMBLNCOP_03439 1.6e-252 araE EGP Major facilitator Superfamily
NMBLNCOP_03440 3.5e-202 araR K transcriptional
NMBLNCOP_03441 6.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMBLNCOP_03442 3.3e-158 yvbU K Transcriptional regulator
NMBLNCOP_03443 7.2e-156 yvbV EG EamA-like transporter family
NMBLNCOP_03444 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NMBLNCOP_03445 1e-195 yvbX S Glycosyl hydrolase
NMBLNCOP_03446 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NMBLNCOP_03447 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NMBLNCOP_03448 4.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NMBLNCOP_03449 2.9e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMBLNCOP_03450 1.3e-196 desK 2.7.13.3 T Histidine kinase
NMBLNCOP_03451 5.3e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
NMBLNCOP_03452 4.4e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NMBLNCOP_03453 2.9e-156 rsbQ S Alpha/beta hydrolase family
NMBLNCOP_03454 3.5e-198 rsbU 3.1.3.3 T response regulator
NMBLNCOP_03455 2.4e-250 galA 3.2.1.89 G arabinogalactan
NMBLNCOP_03456 0.0 lacA 3.2.1.23 G beta-galactosidase
NMBLNCOP_03457 7.2e-150 ganQ P transport
NMBLNCOP_03458 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
NMBLNCOP_03459 1.5e-228 cycB G COG2182 Maltose-binding periplasmic proteins domains
NMBLNCOP_03460 1.8e-184 lacR K Transcriptional regulator
NMBLNCOP_03461 1e-112 yvfI K COG2186 Transcriptional regulators
NMBLNCOP_03462 6.3e-307 yvfH C L-lactate permease
NMBLNCOP_03463 9.4e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NMBLNCOP_03464 1e-31 yvfG S YvfG protein
NMBLNCOP_03465 2.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
NMBLNCOP_03466 6.7e-223 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NMBLNCOP_03467 9.3e-57 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NMBLNCOP_03468 1.3e-108 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NMBLNCOP_03469 3.1e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMBLNCOP_03470 8.3e-193 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NMBLNCOP_03471 7.1e-203 epsI GM pyruvyl transferase
NMBLNCOP_03472 4.4e-194 epsH GT2 S Glycosyltransferase like family 2
NMBLNCOP_03473 1.1e-206 epsG S EpsG family
NMBLNCOP_03474 1.1e-217 epsF GT4 M Glycosyl transferases group 1
NMBLNCOP_03475 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NMBLNCOP_03476 1.1e-222 epsD GT4 M Glycosyl transferase 4-like
NMBLNCOP_03477 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NMBLNCOP_03478 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NMBLNCOP_03479 8.9e-122 ywqC M biosynthesis protein
NMBLNCOP_03480 6.3e-76 slr K transcriptional
NMBLNCOP_03481 1.7e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NMBLNCOP_03483 4.6e-93 padC Q Phenolic acid decarboxylase
NMBLNCOP_03484 2.7e-71 MA20_18690 S Protein of unknown function (DUF3237)
NMBLNCOP_03485 6.4e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NMBLNCOP_03486 1.5e-255 pbpE V Beta-lactamase
NMBLNCOP_03487 9.3e-66
NMBLNCOP_03488 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NMBLNCOP_03489 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NMBLNCOP_03490 5.1e-295 yveA E amino acid
NMBLNCOP_03491 2.6e-106 yvdT K Transcriptional regulator
NMBLNCOP_03492 6.7e-51 ykkC P Small Multidrug Resistance protein
NMBLNCOP_03493 4.1e-50 sugE P Small Multidrug Resistance protein
NMBLNCOP_03494 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
NMBLNCOP_03495 2.3e-173 S Patatin-like phospholipase
NMBLNCOP_03497 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NMBLNCOP_03498 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NMBLNCOP_03499 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NMBLNCOP_03500 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NMBLNCOP_03501 5e-154 malA S Protein of unknown function (DUF1189)
NMBLNCOP_03502 3.9e-148 malD P transport
NMBLNCOP_03503 1e-243 malC P COG1175 ABC-type sugar transport systems, permease components
NMBLNCOP_03504 1.8e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NMBLNCOP_03505 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NMBLNCOP_03506 3.6e-174 yvdE K Transcriptional regulator
NMBLNCOP_03507 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NMBLNCOP_03508 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
NMBLNCOP_03509 1.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NMBLNCOP_03510 1.3e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NMBLNCOP_03511 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMBLNCOP_03512 0.0 yxdM V ABC transporter (permease)
NMBLNCOP_03513 5.6e-141 yvcR V ABC transporter, ATP-binding protein
NMBLNCOP_03514 6.8e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NMBLNCOP_03515 4.3e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMBLNCOP_03516 1.8e-33
NMBLNCOP_03517 1.5e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NMBLNCOP_03518 1.6e-36 crh G Phosphocarrier protein Chr
NMBLNCOP_03519 1.4e-170 whiA K May be required for sporulation
NMBLNCOP_03520 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NMBLNCOP_03521 5.7e-166 rapZ S Displays ATPase and GTPase activities
NMBLNCOP_03522 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NMBLNCOP_03523 5.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NMBLNCOP_03524 5.6e-99 usp CBM50 M protein conserved in bacteria
NMBLNCOP_03525 7.6e-277 S COG0457 FOG TPR repeat
NMBLNCOP_03526 0.0 msbA2 3.6.3.44 V ABC transporter
NMBLNCOP_03528 5.9e-253
NMBLNCOP_03529 4.7e-70
NMBLNCOP_03530 5.8e-65
NMBLNCOP_03531 6.3e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NMBLNCOP_03532 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NMBLNCOP_03533 3.4e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NMBLNCOP_03534 2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NMBLNCOP_03535 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NMBLNCOP_03536 1.1e-226 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NMBLNCOP_03537 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NMBLNCOP_03538 2.6e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NMBLNCOP_03539 1.9e-138 yvpB NU protein conserved in bacteria
NMBLNCOP_03540 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NMBLNCOP_03541 1.5e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NMBLNCOP_03542 7.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NMBLNCOP_03543 3.4e-161 yvoD P COG0370 Fe2 transport system protein B
NMBLNCOP_03544 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NMBLNCOP_03545 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NMBLNCOP_03546 1.6e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NMBLNCOP_03547 3.9e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NMBLNCOP_03548 3.6e-134 yvoA K transcriptional
NMBLNCOP_03549 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NMBLNCOP_03550 1.2e-50 yvlD S Membrane
NMBLNCOP_03551 2.6e-26 pspB KT PspC domain
NMBLNCOP_03552 4.6e-165 yvlB S Putative adhesin
NMBLNCOP_03553 8e-49 yvlA
NMBLNCOP_03554 7.4e-33 yvkN
NMBLNCOP_03555 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMBLNCOP_03556 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NMBLNCOP_03557 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NMBLNCOP_03558 1.2e-30 csbA S protein conserved in bacteria
NMBLNCOP_03559 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NMBLNCOP_03560 1e-99 yvkB K Transcriptional regulator
NMBLNCOP_03561 3.3e-226 yvkA EGP Major facilitator Superfamily
NMBLNCOP_03562 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMBLNCOP_03563 5.3e-56 swrA S Swarming motility protein
NMBLNCOP_03564 2.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NMBLNCOP_03565 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NMBLNCOP_03566 1.6e-123 ftsE D cell division ATP-binding protein FtsE
NMBLNCOP_03567 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
NMBLNCOP_03568 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NMBLNCOP_03569 3.9e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NMBLNCOP_03570 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NMBLNCOP_03571 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NMBLNCOP_03572 4.6e-51
NMBLNCOP_03573 1.9e-08 fliT S bacterial-type flagellum organization
NMBLNCOP_03574 6.5e-69 fliS N flagellar protein FliS
NMBLNCOP_03575 9e-257 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NMBLNCOP_03576 7.8e-52 flaG N flagellar protein FlaG
NMBLNCOP_03577 5.9e-93 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMBLNCOP_03578 5.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NMBLNCOP_03579 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NMBLNCOP_03580 1.3e-49 yviE
NMBLNCOP_03581 3.9e-154 flgL N Belongs to the bacterial flagellin family
NMBLNCOP_03582 1.2e-264 flgK N flagellar hook-associated protein
NMBLNCOP_03583 1.6e-77 flgN NOU FlgN protein
NMBLNCOP_03584 1.4e-38 flgM KNU Negative regulator of flagellin synthesis
NMBLNCOP_03585 2.3e-72 yvyF S flagellar protein
NMBLNCOP_03586 1.2e-126 comFC S Phosphoribosyl transferase domain
NMBLNCOP_03587 3.7e-45 comFB S Late competence development protein ComFB
NMBLNCOP_03588 2.2e-265 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NMBLNCOP_03589 1.1e-153 degV S protein conserved in bacteria
NMBLNCOP_03590 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMBLNCOP_03591 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NMBLNCOP_03592 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NMBLNCOP_03593 6e-163 yvhJ K Transcriptional regulator
NMBLNCOP_03594 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NMBLNCOP_03595 8.6e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NMBLNCOP_03596 2.8e-145 tuaG GT2 M Glycosyltransferase like family 2
NMBLNCOP_03597 6.8e-111 tuaF M protein involved in exopolysaccharide biosynthesis
NMBLNCOP_03598 2.4e-262 tuaE M Teichuronic acid biosynthesis protein
NMBLNCOP_03599 2.9e-257 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMBLNCOP_03600 7.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NMBLNCOP_03601 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMBLNCOP_03602 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NMBLNCOP_03603 1.1e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMBLNCOP_03604 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NMBLNCOP_03605 6e-38
NMBLNCOP_03606 1.8e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NMBLNCOP_03607 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NMBLNCOP_03608 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NMBLNCOP_03609 6.5e-57
NMBLNCOP_03610 9.6e-209 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NMBLNCOP_03611 7.5e-93 ggaA M Glycosyltransferase like family 2
NMBLNCOP_03612 3e-39 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NMBLNCOP_03613 6.6e-105 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NMBLNCOP_03614 2.4e-276 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NMBLNCOP_03615 1.1e-150 tagG GM Transport permease protein
NMBLNCOP_03616 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NMBLNCOP_03617 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
NMBLNCOP_03618 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NMBLNCOP_03619 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NMBLNCOP_03620 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NMBLNCOP_03621 1.2e-260
NMBLNCOP_03622 2.3e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NMBLNCOP_03623 3.5e-190 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NMBLNCOP_03624 1e-265 gerBA EG Spore germination protein
NMBLNCOP_03625 7.5e-200 gerBB E Spore germination protein
NMBLNCOP_03626 1.7e-113 gerAC S Spore germination protein
NMBLNCOP_03627 1.7e-47 ywtG EGP Major facilitator Superfamily
NMBLNCOP_03628 3.2e-170 ywtF K Transcriptional regulator
NMBLNCOP_03629 7.7e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NMBLNCOP_03630 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NMBLNCOP_03631 3.6e-21 ywtC
NMBLNCOP_03632 1.4e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NMBLNCOP_03633 8.6e-70 pgsC S biosynthesis protein
NMBLNCOP_03634 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NMBLNCOP_03635 5.5e-178 rbsR K transcriptional
NMBLNCOP_03636 4.2e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NMBLNCOP_03637 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NMBLNCOP_03638 1.9e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NMBLNCOP_03639 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
NMBLNCOP_03640 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NMBLNCOP_03641 9.6e-92 batE T Sh3 type 3 domain protein
NMBLNCOP_03642 8e-48 ywsA S Protein of unknown function (DUF3892)
NMBLNCOP_03643 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NMBLNCOP_03644 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NMBLNCOP_03645 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NMBLNCOP_03646 1.1e-169 alsR K LysR substrate binding domain
NMBLNCOP_03647 6.1e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NMBLNCOP_03648 3.1e-124 ywrJ
NMBLNCOP_03649 7.2e-124 cotB
NMBLNCOP_03650 1.4e-206 cotH M Spore Coat
NMBLNCOP_03651 1.3e-12
NMBLNCOP_03652 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NMBLNCOP_03653 1.1e-53 S Domain of unknown function (DUF4181)
NMBLNCOP_03654 6.9e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NMBLNCOP_03655 2.6e-80 ywrC K Transcriptional regulator
NMBLNCOP_03656 9.2e-104 ywrB P Chromate transporter
NMBLNCOP_03657 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
NMBLNCOP_03659 4.8e-99 ywqN S NAD(P)H-dependent
NMBLNCOP_03660 1.4e-161 K Transcriptional regulator
NMBLNCOP_03661 8.5e-120 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NMBLNCOP_03662 3.9e-25
NMBLNCOP_03663 3.3e-82 ywqJ S Pre-toxin TG
NMBLNCOP_03664 5.2e-17
NMBLNCOP_03665 4.7e-43
NMBLNCOP_03666 3.3e-213 ywqJ S Pre-toxin TG
NMBLNCOP_03667 3.1e-38 ywqI S Family of unknown function (DUF5344)
NMBLNCOP_03668 7.7e-20 S Domain of unknown function (DUF5082)
NMBLNCOP_03669 9.2e-152 ywqG S Domain of unknown function (DUF1963)
NMBLNCOP_03670 4.1e-245 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMBLNCOP_03671 2.1e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NMBLNCOP_03672 9e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NMBLNCOP_03673 2e-116 ywqC M biosynthesis protein
NMBLNCOP_03674 1.2e-17
NMBLNCOP_03675 1.3e-306 ywqB S SWIM zinc finger
NMBLNCOP_03676 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NMBLNCOP_03677 2.6e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NMBLNCOP_03678 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
NMBLNCOP_03679 3.7e-57 ssbB L Single-stranded DNA-binding protein
NMBLNCOP_03680 4.9e-39 ywpG
NMBLNCOP_03681 1.1e-66 ywpF S YwpF-like protein
NMBLNCOP_03682 9.7e-83 srtA 3.4.22.70 M Sortase family
NMBLNCOP_03683 0.0 M1-568 M cell wall anchor domain
NMBLNCOP_03684 1.5e-173 M1-574 T Transcriptional regulatory protein, C terminal
NMBLNCOP_03685 0.0 ywpD T PhoQ Sensor
NMBLNCOP_03686 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NMBLNCOP_03687 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NMBLNCOP_03688 7.5e-197 S aspartate phosphatase
NMBLNCOP_03689 8.3e-140 flhP N flagellar basal body
NMBLNCOP_03690 6.4e-124 flhO N flagellar basal body
NMBLNCOP_03691 3.5e-180 mbl D Rod shape-determining protein
NMBLNCOP_03692 3e-44 spoIIID K Stage III sporulation protein D
NMBLNCOP_03693 6.1e-70 ywoH K COG1846 Transcriptional regulators
NMBLNCOP_03694 2.7e-211 ywoG EGP Major facilitator Superfamily
NMBLNCOP_03696 1.4e-227 ywoF P Right handed beta helix region
NMBLNCOP_03697 2.8e-279 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NMBLNCOP_03698 1.8e-240 ywoD EGP Major facilitator superfamily
NMBLNCOP_03699 6.8e-104 phzA Q Isochorismatase family
NMBLNCOP_03700 1.5e-77
NMBLNCOP_03701 2.5e-225 amt P Ammonium transporter
NMBLNCOP_03702 1.6e-58 nrgB K Belongs to the P(II) protein family
NMBLNCOP_03703 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NMBLNCOP_03704 7.8e-73 ywnJ S VanZ like family
NMBLNCOP_03705 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NMBLNCOP_03706 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NMBLNCOP_03707 8.6e-13 ywnC S Family of unknown function (DUF5362)
NMBLNCOP_03708 2.9e-70 ywnF S Family of unknown function (DUF5392)
NMBLNCOP_03709 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMBLNCOP_03710 2.6e-143 mta K transcriptional
NMBLNCOP_03711 1.7e-58 ywnC S Family of unknown function (DUF5362)
NMBLNCOP_03712 1.1e-113 ywnB S NAD(P)H-binding
NMBLNCOP_03713 3.7e-64 ywnA K Transcriptional regulator
NMBLNCOP_03714 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NMBLNCOP_03715 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NMBLNCOP_03716 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NMBLNCOP_03717 3.8e-11 csbD K CsbD-like
NMBLNCOP_03718 5.1e-84 ywmF S Peptidase M50
NMBLNCOP_03719 7.9e-104 S response regulator aspartate phosphatase
NMBLNCOP_03720 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NMBLNCOP_03721 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NMBLNCOP_03723 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NMBLNCOP_03724 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NMBLNCOP_03725 9.8e-178 spoIID D Stage II sporulation protein D
NMBLNCOP_03726 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMBLNCOP_03727 8.2e-134 ywmB S TATA-box binding
NMBLNCOP_03728 1.3e-32 ywzB S membrane
NMBLNCOP_03729 4.8e-87 ywmA
NMBLNCOP_03730 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NMBLNCOP_03731 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NMBLNCOP_03732 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NMBLNCOP_03733 4.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NMBLNCOP_03734 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMBLNCOP_03735 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NMBLNCOP_03736 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMBLNCOP_03737 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NMBLNCOP_03738 1.6e-61 atpI S ATP synthase
NMBLNCOP_03739 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NMBLNCOP_03740 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NMBLNCOP_03741 2.7e-94 ywlG S Belongs to the UPF0340 family
NMBLNCOP_03742 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NMBLNCOP_03743 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMBLNCOP_03744 1.7e-91 mntP P Probably functions as a manganese efflux pump
NMBLNCOP_03745 2.4e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NMBLNCOP_03746 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NMBLNCOP_03747 2.3e-111 spoIIR S stage II sporulation protein R
NMBLNCOP_03748 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
NMBLNCOP_03750 6.6e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NMBLNCOP_03751 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NMBLNCOP_03752 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMBLNCOP_03753 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NMBLNCOP_03754 8.6e-160 ywkB S Membrane transport protein
NMBLNCOP_03755 0.0 sfcA 1.1.1.38 C malic enzyme
NMBLNCOP_03756 7e-104 tdk 2.7.1.21 F thymidine kinase
NMBLNCOP_03757 1.1e-32 rpmE J Binds the 23S rRNA
NMBLNCOP_03758 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NMBLNCOP_03759 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NMBLNCOP_03760 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMBLNCOP_03761 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NMBLNCOP_03762 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NMBLNCOP_03763 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NMBLNCOP_03764 1.5e-89 ywjG S Domain of unknown function (DUF2529)
NMBLNCOP_03765 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NMBLNCOP_03766 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NMBLNCOP_03767 2.8e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NMBLNCOP_03768 0.0 fadF C COG0247 Fe-S oxidoreductase
NMBLNCOP_03769 4.4e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NMBLNCOP_03770 1.6e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NMBLNCOP_03771 2.7e-42 ywjC
NMBLNCOP_03772 1.2e-94 ywjB H RibD C-terminal domain
NMBLNCOP_03773 0.0 ywjA V ABC transporter
NMBLNCOP_03774 1e-284 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMBLNCOP_03775 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
NMBLNCOP_03776 3.6e-94 narJ 1.7.5.1 C nitrate reductase
NMBLNCOP_03777 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
NMBLNCOP_03778 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMBLNCOP_03779 7e-86 arfM T cyclic nucleotide binding
NMBLNCOP_03780 1.8e-138 ywiC S YwiC-like protein
NMBLNCOP_03781 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
NMBLNCOP_03782 1e-213 narK P COG2223 Nitrate nitrite transporter
NMBLNCOP_03783 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NMBLNCOP_03784 4.7e-73 ywiB S protein conserved in bacteria
NMBLNCOP_03785 1e-07 S Bacteriocin subtilosin A
NMBLNCOP_03786 4.9e-270 C Fe-S oxidoreductases
NMBLNCOP_03788 3.3e-132 cbiO V ABC transporter
NMBLNCOP_03789 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NMBLNCOP_03790 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
NMBLNCOP_03791 1.1e-247 L Peptidase, M16
NMBLNCOP_03793 2.7e-231 ywhL CO amine dehydrogenase activity
NMBLNCOP_03794 5.6e-189 ywhK CO amine dehydrogenase activity
NMBLNCOP_03795 1.7e-85 S aspartate phosphatase
NMBLNCOP_03797 4.8e-53 ywhH S Aminoacyl-tRNA editing domain
NMBLNCOP_03798 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
NMBLNCOP_03799 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NMBLNCOP_03800 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NMBLNCOP_03801 2e-94 ywhD S YwhD family
NMBLNCOP_03802 5.1e-119 ywhC S Peptidase family M50
NMBLNCOP_03803 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NMBLNCOP_03804 3.3e-71 ywhA K Transcriptional regulator
NMBLNCOP_03805 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMBLNCOP_03807 4.4e-237 mmr U Major Facilitator Superfamily
NMBLNCOP_03808 6.2e-79 yffB K Transcriptional regulator
NMBLNCOP_03809 2.7e-88 ywgA 2.1.1.72, 3.1.21.3
NMBLNCOP_03810 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
NMBLNCOP_03811 3.4e-35 ywzC S Belongs to the UPF0741 family
NMBLNCOP_03812 1e-110 rsfA_1
NMBLNCOP_03813 2.2e-157 ywfM EG EamA-like transporter family
NMBLNCOP_03814 1.9e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NMBLNCOP_03815 2.4e-156 cysL K Transcriptional regulator
NMBLNCOP_03816 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NMBLNCOP_03817 3.3e-146 ywfI C May function as heme-dependent peroxidase
NMBLNCOP_03818 6.4e-137 IQ Enoyl-(Acyl carrier protein) reductase
NMBLNCOP_03819 1.5e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
NMBLNCOP_03820 1.9e-209 bacE EGP Major facilitator Superfamily
NMBLNCOP_03821 2.3e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NMBLNCOP_03822 1.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMBLNCOP_03823 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NMBLNCOP_03824 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NMBLNCOP_03825 1.7e-205 ywfA EGP Major facilitator Superfamily
NMBLNCOP_03826 2.8e-249 lysP E amino acid
NMBLNCOP_03827 0.0 rocB E arginine degradation protein
NMBLNCOP_03828 2.7e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NMBLNCOP_03829 3.7e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NMBLNCOP_03830 1.2e-77
NMBLNCOP_03831 1.3e-86 spsL 5.1.3.13 M Spore Coat
NMBLNCOP_03832 2e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NMBLNCOP_03833 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NMBLNCOP_03834 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NMBLNCOP_03835 7.9e-188 spsG M Spore Coat
NMBLNCOP_03836 2.8e-131 spsF M Spore Coat
NMBLNCOP_03837 7.1e-214 spsE 2.5.1.56 M acid synthase
NMBLNCOP_03838 1.7e-162 spsD 2.3.1.210 K Spore Coat
NMBLNCOP_03839 3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
NMBLNCOP_03840 4.3e-269 spsB M Capsule polysaccharide biosynthesis protein
NMBLNCOP_03841 2.4e-144 spsA M Spore Coat
NMBLNCOP_03842 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NMBLNCOP_03843 4.3e-59 ywdK S small membrane protein
NMBLNCOP_03844 3.7e-238 ywdJ F Xanthine uracil
NMBLNCOP_03845 7.7e-49 ywdI S Family of unknown function (DUF5327)
NMBLNCOP_03846 5.9e-255 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NMBLNCOP_03847 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NMBLNCOP_03848 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
NMBLNCOP_03849 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NMBLNCOP_03850 2e-28 ywdA
NMBLNCOP_03851 6.8e-294 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NMBLNCOP_03852 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMBLNCOP_03853 1.1e-138 focA P Formate/nitrite transporter
NMBLNCOP_03854 7e-150 sacT K transcriptional antiterminator
NMBLNCOP_03856 0.0 vpr O Belongs to the peptidase S8 family
NMBLNCOP_03857 1.2e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMBLNCOP_03858 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NMBLNCOP_03859 8.6e-202 rodA D Belongs to the SEDS family
NMBLNCOP_03860 4.7e-205 S Acetyltransferase
NMBLNCOP_03861 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NMBLNCOP_03862 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NMBLNCOP_03863 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NMBLNCOP_03864 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NMBLNCOP_03865 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NMBLNCOP_03866 1e-35 ywzA S membrane
NMBLNCOP_03867 6.2e-301 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NMBLNCOP_03868 3.4e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NMBLNCOP_03869 9.5e-60 gtcA S GtrA-like protein
NMBLNCOP_03870 1.1e-121 ywcC K transcriptional regulator
NMBLNCOP_03872 9.8e-49 ywcB S Protein of unknown function, DUF485
NMBLNCOP_03873 5.8e-267 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMBLNCOP_03874 2.4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NMBLNCOP_03875 1.6e-222 ywbN P Dyp-type peroxidase family protein
NMBLNCOP_03876 1.2e-184 ycdO P periplasmic lipoprotein involved in iron transport
NMBLNCOP_03877 1.4e-251 P COG0672 High-affinity Fe2 Pb2 permease
NMBLNCOP_03878 9.4e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NMBLNCOP_03879 1.1e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NMBLNCOP_03880 4.3e-153 ywbI K Transcriptional regulator
NMBLNCOP_03881 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NMBLNCOP_03882 4e-111 ywbG M effector of murein hydrolase
NMBLNCOP_03883 4e-207 ywbF EGP Major facilitator Superfamily
NMBLNCOP_03884 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
NMBLNCOP_03885 1.8e-215 ywbD 2.1.1.191 J Methyltransferase
NMBLNCOP_03886 2.2e-66 ywbC 4.4.1.5 E glyoxalase
NMBLNCOP_03887 4.5e-72 E LysE type translocator
NMBLNCOP_03888 6.8e-75 S YqcI/YcgG family
NMBLNCOP_03889 2.1e-107 ywbB S Protein of unknown function (DUF2711)
NMBLNCOP_03890 2.3e-240 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMBLNCOP_03891 5.6e-267 epr 3.4.21.62 O Belongs to the peptidase S8 family
NMBLNCOP_03892 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMBLNCOP_03893 4e-153 sacY K transcriptional antiterminator
NMBLNCOP_03894 4.7e-165 gspA M General stress
NMBLNCOP_03895 6.3e-123 ywaF S Integral membrane protein
NMBLNCOP_03896 4e-87 ywaE K Transcriptional regulator
NMBLNCOP_03897 3.7e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NMBLNCOP_03898 1.1e-248 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NMBLNCOP_03899 1.4e-92 K Helix-turn-helix XRE-family like proteins
NMBLNCOP_03900 5.9e-37 4.1.1.44 S Carboxymuconolactone decarboxylase family
NMBLNCOP_03901 5.7e-129 ynfM EGP Major facilitator Superfamily
NMBLNCOP_03902 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NMBLNCOP_03903 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NMBLNCOP_03904 5e-14 S D-Ala-teichoic acid biosynthesis protein
NMBLNCOP_03905 1.3e-290 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMBLNCOP_03906 1.2e-232 dltB M membrane protein involved in D-alanine export
NMBLNCOP_03907 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMBLNCOP_03908 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NMBLNCOP_03909 2.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NMBLNCOP_03910 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NMBLNCOP_03911 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NMBLNCOP_03912 1.9e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NMBLNCOP_03913 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMBLNCOP_03914 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NMBLNCOP_03915 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NMBLNCOP_03916 1.1e-19 yxzF
NMBLNCOP_03917 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NMBLNCOP_03918 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NMBLNCOP_03919 2.4e-212 yxlH EGP Major facilitator Superfamily
NMBLNCOP_03920 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NMBLNCOP_03921 3.1e-164 yxlF V ABC transporter, ATP-binding protein
NMBLNCOP_03922 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
NMBLNCOP_03923 2.2e-28
NMBLNCOP_03924 2.5e-47 yxlC S Family of unknown function (DUF5345)
NMBLNCOP_03925 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NMBLNCOP_03926 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NMBLNCOP_03927 2.8e-159 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NMBLNCOP_03928 0.0 cydD V ATP-binding protein
NMBLNCOP_03929 3.5e-310 cydD V ATP-binding
NMBLNCOP_03930 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NMBLNCOP_03931 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
NMBLNCOP_03932 1.5e-229 cimH C COG3493 Na citrate symporter
NMBLNCOP_03933 2.3e-311 3.4.24.84 O Peptidase family M48
NMBLNCOP_03935 3.1e-153 yxkH G Polysaccharide deacetylase
NMBLNCOP_03936 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NMBLNCOP_03937 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
NMBLNCOP_03938 1.2e-274 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMBLNCOP_03939 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMBLNCOP_03940 7.4e-75 yxkC S Domain of unknown function (DUF4352)
NMBLNCOP_03941 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NMBLNCOP_03942 2.4e-78 S Protein of unknown function (DUF1453)
NMBLNCOP_03943 1.1e-191 yxjM T Signal transduction histidine kinase
NMBLNCOP_03944 3.4e-115 K helix_turn_helix, Lux Regulon
NMBLNCOP_03945 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NMBLNCOP_03948 2.3e-84 yxjI S LURP-one-related
NMBLNCOP_03949 7.3e-194 yxjG 2.1.1.14 E Methionine synthase
NMBLNCOP_03950 1.5e-216 yxjG 2.1.1.14 E Methionine synthase
NMBLNCOP_03951 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NMBLNCOP_03952 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NMBLNCOP_03953 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NMBLNCOP_03954 7.5e-253 yxjC EG COG2610 H gluconate symporter and related permeases
NMBLNCOP_03955 1.3e-159 rlmA 2.1.1.187 Q Methyltransferase domain
NMBLNCOP_03956 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMBLNCOP_03957 1.2e-104 T Domain of unknown function (DUF4163)
NMBLNCOP_03958 3e-47 yxiS
NMBLNCOP_03959 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NMBLNCOP_03960 6.6e-224 citH C Citrate transporter
NMBLNCOP_03961 1.1e-143 exoK GH16 M licheninase activity
NMBLNCOP_03962 3.1e-150 licT K transcriptional antiterminator
NMBLNCOP_03963 1.7e-93
NMBLNCOP_03964 1.1e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
NMBLNCOP_03965 1.1e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NMBLNCOP_03966 2.8e-213 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NMBLNCOP_03967 5.5e-53 padR K Transcriptional regulator PadR-like family
NMBLNCOP_03968 6.5e-61 S Protein of unknown function (DUF2812)
NMBLNCOP_03970 1.2e-43 yxiJ S YxiJ-like protein
NMBLNCOP_03973 1.2e-34
NMBLNCOP_03974 4.3e-83 yxiI S Protein of unknown function (DUF2716)
NMBLNCOP_03975 2.6e-139
NMBLNCOP_03976 1.3e-72 yxiG
NMBLNCOP_03977 1.1e-37
NMBLNCOP_03978 4.8e-163 yxxF EG EamA-like transporter family
NMBLNCOP_03979 1.3e-126 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMBLNCOP_03980 4.9e-123 1.14.11.45 E 2OG-Fe dioxygenase
NMBLNCOP_03981 3.1e-72 yxiE T Belongs to the universal stress protein A family
NMBLNCOP_03982 4.6e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMBLNCOP_03983 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMBLNCOP_03984 5.5e-53
NMBLNCOP_03985 4.2e-47
NMBLNCOP_03986 3.4e-281 S nuclease activity
NMBLNCOP_03987 4.7e-39 yxiC S Family of unknown function (DUF5344)
NMBLNCOP_03988 2.3e-20 S Domain of unknown function (DUF5082)
NMBLNCOP_03989 1.5e-261 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NMBLNCOP_03991 1.1e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NMBLNCOP_03992 2.2e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
NMBLNCOP_03993 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NMBLNCOP_03994 4.8e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NMBLNCOP_03995 2.7e-177 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NMBLNCOP_03996 2.3e-251 lysP E amino acid
NMBLNCOP_03997 2.1e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NMBLNCOP_03998 1.7e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMBLNCOP_03999 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NMBLNCOP_04000 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NMBLNCOP_04001 5.7e-152 yxxB S Domain of Unknown Function (DUF1206)
NMBLNCOP_04002 3e-196 eutH E Ethanolamine utilisation protein, EutH
NMBLNCOP_04003 5.6e-250 yxeQ S MmgE/PrpD family
NMBLNCOP_04004 4.7e-213 yxeP 3.5.1.47 E hydrolase activity
NMBLNCOP_04005 2.7e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NMBLNCOP_04006 1.3e-106 yxeN P COG0765 ABC-type amino acid transport system, permease component
NMBLNCOP_04007 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
NMBLNCOP_04008 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMBLNCOP_04009 7e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMBLNCOP_04010 5e-187 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NMBLNCOP_04011 6.2e-151 yidA S hydrolases of the HAD superfamily
NMBLNCOP_04014 1.3e-20 yxeE
NMBLNCOP_04015 3.6e-15 yxeD
NMBLNCOP_04016 8.5e-69
NMBLNCOP_04017 1.1e-175 fhuD P ABC transporter
NMBLNCOP_04018 1.7e-57 yxeA S Protein of unknown function (DUF1093)
NMBLNCOP_04019 0.0 yxdM V ABC transporter (permease)
NMBLNCOP_04020 9.4e-141 yxdL V ABC transporter, ATP-binding protein
NMBLNCOP_04021 2.6e-180 T PhoQ Sensor
NMBLNCOP_04022 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMBLNCOP_04023 3e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NMBLNCOP_04024 1.4e-137 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NMBLNCOP_04025 6.6e-167 iolH G Xylose isomerase-like TIM barrel
NMBLNCOP_04026 4.7e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NMBLNCOP_04027 5.6e-234 iolF EGP Major facilitator Superfamily
NMBLNCOP_04028 7.5e-174 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NMBLNCOP_04029 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NMBLNCOP_04030 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NMBLNCOP_04031 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NMBLNCOP_04032 1.5e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMBLNCOP_04033 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NMBLNCOP_04034 8.3e-176 iolS C Aldo keto reductase
NMBLNCOP_04036 8.3e-48 yxcD S Protein of unknown function (DUF2653)
NMBLNCOP_04037 2.1e-244 csbC EGP Major facilitator Superfamily
NMBLNCOP_04038 0.0 htpG O Molecular chaperone. Has ATPase activity
NMBLNCOP_04040 1.8e-150 IQ Enoyl-(Acyl carrier protein) reductase
NMBLNCOP_04041 9.1e-209 yxbF K Bacterial regulatory proteins, tetR family
NMBLNCOP_04042 3.8e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NMBLNCOP_04043 6.4e-25 yxaI S membrane protein domain
NMBLNCOP_04044 2e-92 S PQQ-like domain
NMBLNCOP_04045 6.7e-64 S Family of unknown function (DUF5391)
NMBLNCOP_04046 1.4e-75 yxaI S membrane protein domain
NMBLNCOP_04047 4.6e-227 P Protein of unknown function (DUF418)
NMBLNCOP_04048 1.9e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
NMBLNCOP_04049 2.7e-100 yxaF K Transcriptional regulator
NMBLNCOP_04050 3.3e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMBLNCOP_04051 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NMBLNCOP_04052 5.2e-50 S LrgA family
NMBLNCOP_04053 2.6e-118 yxaC M effector of murein hydrolase
NMBLNCOP_04054 2.4e-192 yxaB GM Polysaccharide pyruvyl transferase
NMBLNCOP_04055 4.3e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NMBLNCOP_04056 7.3e-127 gntR K transcriptional
NMBLNCOP_04057 7.3e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NMBLNCOP_04058 3.8e-230 gntP EG COG2610 H gluconate symporter and related permeases
NMBLNCOP_04059 1.1e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NMBLNCOP_04060 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NMBLNCOP_04061 1.2e-285 ahpF O Alkyl hydroperoxide reductase
NMBLNCOP_04063 4.1e-44 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
NMBLNCOP_04064 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NMBLNCOP_04065 0.0 L SNF2 family N-terminal domain
NMBLNCOP_04066 0.0 S PglZ domain
NMBLNCOP_04067 7.6e-307 2.1.1.72 V restriction
NMBLNCOP_04068 0.0 zmpC D nuclear chromosome segregation
NMBLNCOP_04069 2.3e-53 S Domain of unknown function (DUF1788)
NMBLNCOP_04070 1.5e-24 S inner membrane protein DUF1819
NMBLNCOP_04071 2e-90 tnpR1 L Resolvase, N terminal domain
NMBLNCOP_04072 2.3e-64
NMBLNCOP_04073 3.4e-49 spoIVCA L Recombinase
NMBLNCOP_04074 6.5e-108 spoIVCA L Recombinase
NMBLNCOP_04075 5.9e-72 spoIVCA L Recombinase
NMBLNCOP_04076 4.4e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NMBLNCOP_04077 1.1e-09 S YyzF-like protein
NMBLNCOP_04078 7.7e-65
NMBLNCOP_04080 1.9e-206 yycP
NMBLNCOP_04081 1.1e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NMBLNCOP_04082 8.4e-84 yycN 2.3.1.128 K Acetyltransferase
NMBLNCOP_04083 1.5e-187 S aspartate phosphatase
NMBLNCOP_04085 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NMBLNCOP_04086 9.7e-261 rocE E amino acid
NMBLNCOP_04087 7.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NMBLNCOP_04088 7.6e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NMBLNCOP_04089 9.6e-171 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
NMBLNCOP_04090 3.4e-94 K PFAM response regulator receiver
NMBLNCOP_04091 2.3e-74 S Peptidase propeptide and YPEB domain
NMBLNCOP_04092 1.1e-17 S Peptidase propeptide and YPEB domain
NMBLNCOP_04093 2.5e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMBLNCOP_04094 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NMBLNCOP_04095 3.6e-154 yycI S protein conserved in bacteria
NMBLNCOP_04096 1.7e-257 yycH S protein conserved in bacteria
NMBLNCOP_04097 0.0 vicK 2.7.13.3 T Histidine kinase
NMBLNCOP_04098 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMBLNCOP_04103 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NMBLNCOP_04104 2e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMBLNCOP_04105 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NMBLNCOP_04106 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NMBLNCOP_04108 1.9e-15 yycC K YycC-like protein
NMBLNCOP_04109 3e-218 yeaN P COG2807 Cyanate permease
NMBLNCOP_04110 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NMBLNCOP_04111 2.2e-73 rplI J binds to the 23S rRNA
NMBLNCOP_04112 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NMBLNCOP_04113 2.9e-160 yybS S membrane
NMBLNCOP_04115 1.9e-83 cotF M Spore coat protein
NMBLNCOP_04116 7.5e-67 ydeP3 K Transcriptional regulator
NMBLNCOP_04117 2.1e-163 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NMBLNCOP_04118 1.5e-58
NMBLNCOP_04120 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NMBLNCOP_04121 6.9e-109 K TipAS antibiotic-recognition domain
NMBLNCOP_04122 9e-123
NMBLNCOP_04123 6.5e-66 yybH S SnoaL-like domain
NMBLNCOP_04124 3.1e-121 yybG S Pentapeptide repeat-containing protein
NMBLNCOP_04125 2.5e-217 ynfM EGP Major facilitator Superfamily
NMBLNCOP_04126 1.7e-162 yybE K Transcriptional regulator
NMBLNCOP_04127 2e-79 yjcF S Acetyltransferase (GNAT) domain
NMBLNCOP_04128 2.3e-76 yybC
NMBLNCOP_04129 3e-127 S Metallo-beta-lactamase superfamily
NMBLNCOP_04130 5.6e-77 yybA 2.3.1.57 K transcriptional
NMBLNCOP_04131 1.3e-70 yjcF S Acetyltransferase (GNAT) domain
NMBLNCOP_04132 5.5e-96 yyaS S Membrane
NMBLNCOP_04133 3.2e-92 yyaR K Acetyltransferase (GNAT) domain
NMBLNCOP_04134 7.8e-66 yyaQ S YjbR
NMBLNCOP_04135 3.6e-105 yyaP 1.5.1.3 H RibD C-terminal domain
NMBLNCOP_04136 6.6e-246 tetL EGP Major facilitator Superfamily
NMBLNCOP_04137 1.1e-42 yyaL O Highly conserved protein containing a thioredoxin domain
NMBLNCOP_04138 5.1e-61 yyaN K MerR HTH family regulatory protein
NMBLNCOP_04139 7.4e-161 yyaM EG EamA-like transporter family
NMBLNCOP_04140 2.9e-26 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NMBLNCOP_04141 4.1e-55 L Recombinase
NMBLNCOP_04143 7.8e-61
NMBLNCOP_04145 7e-44 S Domain of unknown function with cystatin-like fold (DUF4467)
NMBLNCOP_04146 5.5e-81 yddI
NMBLNCOP_04147 3.2e-186 yddH CBM50 M Lysozyme-like
NMBLNCOP_04148 0.0 yddG S maturation of SSU-rRNA
NMBLNCOP_04149 4.9e-54 S Domain of unknown function (DUF1874)
NMBLNCOP_04150 0.0 yddE S AAA-like domain
NMBLNCOP_04151 2e-94 yddD S TcpE family
NMBLNCOP_04152 3e-40 yddC
NMBLNCOP_04153 3.4e-165 yddB S Conjugative transposon protein TcpC
NMBLNCOP_04155 2.3e-41 yddA
NMBLNCOP_04158 3.1e-203 nicK L Replication initiation factor
NMBLNCOP_04159 3.8e-268 ydcQ D Ftsk spoiiie family protein
NMBLNCOP_04160 5.1e-63 S Bacterial protein of unknown function (DUF961)
NMBLNCOP_04162 6.8e-35
NMBLNCOP_04163 3.5e-14
NMBLNCOP_04164 1.4e-41 yvaO K Transcriptional
NMBLNCOP_04165 5.1e-45 immA E IrrE N-terminal-like domain
NMBLNCOP_04166 1.8e-66 S response regulator aspartate phosphatase
NMBLNCOP_04167 9e-43
NMBLNCOP_04168 1.3e-46 S SIR2-like domain
NMBLNCOP_04169 3.5e-08
NMBLNCOP_04170 3.4e-24 yyaL O Highly conserved protein containing a thioredoxin domain
NMBLNCOP_04171 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NMBLNCOP_04172 3.4e-166 yyaK S CAAX protease self-immunity
NMBLNCOP_04173 3.6e-244 EGP Major facilitator superfamily
NMBLNCOP_04174 3.1e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NMBLNCOP_04175 8.4e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMBLNCOP_04176 5.8e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NMBLNCOP_04177 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
NMBLNCOP_04178 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NMBLNCOP_04179 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NMBLNCOP_04180 2.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
NMBLNCOP_04181 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NMBLNCOP_04182 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMBLNCOP_04183 2.3e-33 yyzM S protein conserved in bacteria
NMBLNCOP_04184 8.1e-177 yyaD S Membrane
NMBLNCOP_04185 1.6e-111 yyaC S Sporulation protein YyaC
NMBLNCOP_04186 2.1e-149 spo0J K Belongs to the ParB family
NMBLNCOP_04187 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NMBLNCOP_04188 9.6e-74 S Bacterial PH domain
NMBLNCOP_04189 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NMBLNCOP_04190 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NMBLNCOP_04191 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NMBLNCOP_04192 6.4e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NMBLNCOP_04193 1.5e-107 jag S single-stranded nucleic acid binding R3H
NMBLNCOP_04194 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMBLNCOP_04195 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NMBLNCOP_04196 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NMBLNCOP_04197 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NMBLNCOP_04198 2.4e-33 yaaA S S4 domain
NMBLNCOP_04199 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NMBLNCOP_04200 1.8e-37 yaaB S Domain of unknown function (DUF370)
NMBLNCOP_04201 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMBLNCOP_04202 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMBLNCOP_04203 1.2e-50 S Oxidoreductase family, C-terminal alpha/beta domain
NMBLNCOP_04204 1.9e-82 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMBLNCOP_04205 1.4e-39 lytB 3.5.1.28 D Stage II sporulation protein
NMBLNCOP_04206 9.6e-50 wapA M COG3209 Rhs family protein
NMBLNCOP_04207 3.4e-31 csfB S Inhibitor of sigma-G Gin
NMBLNCOP_04208 7.6e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NMBLNCOP_04209 7.6e-203 yaaN P Belongs to the TelA family
NMBLNCOP_04210 3.3e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NMBLNCOP_04211 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NMBLNCOP_04212 2.2e-54 yaaQ S protein conserved in bacteria
NMBLNCOP_04213 1.5e-71 yaaR S protein conserved in bacteria
NMBLNCOP_04214 1.1e-181 holB 2.7.7.7 L DNA polymerase III
NMBLNCOP_04215 6.1e-146 yaaT S stage 0 sporulation protein
NMBLNCOP_04216 4.8e-31 yabA L Involved in initiation control of chromosome replication
NMBLNCOP_04217 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
NMBLNCOP_04218 4.3e-49 yazA L endonuclease containing a URI domain
NMBLNCOP_04219 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NMBLNCOP_04220 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NMBLNCOP_04221 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMBLNCOP_04222 1e-142 tatD L hydrolase, TatD
NMBLNCOP_04223 2e-167 rpfB GH23 T protein conserved in bacteria
NMBLNCOP_04224 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NMBLNCOP_04225 2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NMBLNCOP_04226 1.6e-136 yabG S peptidase
NMBLNCOP_04227 7.8e-39 veg S protein conserved in bacteria
NMBLNCOP_04228 2e-26 sspF S DNA topological change
NMBLNCOP_04229 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NMBLNCOP_04230 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NMBLNCOP_04231 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NMBLNCOP_04232 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NMBLNCOP_04233 1.2e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NMBLNCOP_04234 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMBLNCOP_04235 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NMBLNCOP_04236 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NMBLNCOP_04237 2.4e-39 yabK S Peptide ABC transporter permease
NMBLNCOP_04238 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NMBLNCOP_04239 1.5e-92 spoVT K stage V sporulation protein
NMBLNCOP_04240 8.4e-285 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMBLNCOP_04241 5e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NMBLNCOP_04242 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NMBLNCOP_04243 1.5e-49 yabP S Sporulation protein YabP
NMBLNCOP_04244 4.3e-107 yabQ S spore cortex biosynthesis protein
NMBLNCOP_04245 1.1e-44 divIC D Septum formation initiator
NMBLNCOP_04246 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NMBLNCOP_04249 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NMBLNCOP_04250 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NMBLNCOP_04251 2.8e-185 KLT serine threonine protein kinase
NMBLNCOP_04252 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NMBLNCOP_04253 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NMBLNCOP_04254 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NMBLNCOP_04255 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NMBLNCOP_04256 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NMBLNCOP_04257 7.7e-152 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NMBLNCOP_04258 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NMBLNCOP_04259 1.7e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NMBLNCOP_04260 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NMBLNCOP_04261 9.6e-166 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NMBLNCOP_04262 7.7e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NMBLNCOP_04263 3.8e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NMBLNCOP_04264 3e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NMBLNCOP_04265 4.1e-30 yazB K transcriptional
NMBLNCOP_04266 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMBLNCOP_04267 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NMBLNCOP_04268 4e-53 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NMBLNCOP_04269 1.5e-49 wapA M COG3209 Rhs family protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)