ORF_ID e_value Gene_name EC_number CAZy COGs Description
MHKHGFKK_00002 8.3e-51 yfhH S Protein of unknown function (DUF1811)
MHKHGFKK_00003 2.5e-144 recX 2.4.1.337 GT4 S Modulates RecA activity
MHKHGFKK_00005 3.8e-24 yfhD S YfhD-like protein
MHKHGFKK_00006 7.6e-146 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHKHGFKK_00008 1.3e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHKHGFKK_00009 6e-258 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpC family
MHKHGFKK_00010 7.7e-183 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHKHGFKK_00011 3.3e-109 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MHKHGFKK_00012 2.3e-262 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHKHGFKK_00013 6.8e-207 bacI V COG0577 ABC-type antimicrobial peptide transport system, permease component
MHKHGFKK_00014 2.1e-120 V ATPases associated with a variety of cellular activities
MHKHGFKK_00015 2e-186 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MHKHGFKK_00017 1.1e-07
MHKHGFKK_00018 5.9e-86 S Stage II sporulation protein M
MHKHGFKK_00019 2e-126 V ABC transporter
MHKHGFKK_00021 1.4e-43 S Bacteriocin class IId cyclical uberolysin-like
MHKHGFKK_00023 0.0 XK27_10205
MHKHGFKK_00024 1.6e-162 tnp4 L Transposase, Mutator family
MHKHGFKK_00026 1.9e-29 yodI
MHKHGFKK_00027 7e-152 yjaZ O Zn-dependent protease
MHKHGFKK_00028 3.3e-132 yodH Q Methyltransferase
MHKHGFKK_00029 4.2e-116 S PD-(D/E)XK nuclease family transposase
MHKHGFKK_00030 0.0 gtfC 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MHKHGFKK_00031 1.2e-140 S HIRAN
MHKHGFKK_00032 3e-113 IQ Enoyl-(Acyl carrier protein) reductase
MHKHGFKK_00033 6e-192 srlR2 2.7.1.202 K transcriptional regulator, MtlR
MHKHGFKK_00034 1.3e-44 gutM K Glucitol operon activator protein (GutM)
MHKHGFKK_00035 1.7e-80 srlA G PTS system enzyme II sorbitol-specific factor
MHKHGFKK_00036 2.2e-161 srlE 2.7.1.198 G PTS system glucitol sorbitol-specific transporter subunit IIB
MHKHGFKK_00037 1.1e-38 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MHKHGFKK_00038 6.5e-77 tal 2.2.1.2 H COG0176 Transaldolase
MHKHGFKK_00039 4.7e-261 L Transposase, IS4 family protein
MHKHGFKK_00040 1.8e-29 K Cro/C1-type HTH DNA-binding domain
MHKHGFKK_00041 2.9e-102 K Periplasmic binding protein domain
MHKHGFKK_00042 1.3e-51 fucU 5.1.3.29 G Belongs to the RbsD FucU family
MHKHGFKK_00043 7.5e-227 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MHKHGFKK_00044 1.3e-121 rbsC G Belongs to the binding-protein-dependent transport system permease family
MHKHGFKK_00045 1.9e-122 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MHKHGFKK_00046 8.6e-207 rhaB 2.7.1.189, 2.7.1.5 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MHKHGFKK_00047 0.0 fucI 5.3.1.25, 5.3.1.3 G Converts the aldose L-fucose into the corresponding ketose L-fuculose
MHKHGFKK_00048 3.3e-102 fucA 2.7.1.189, 4.1.2.17, 4.1.2.19, 5.1.3.4 G Aldolase
MHKHGFKK_00049 2e-238 araB G FGGY family of carbohydrate kinases, C-terminal domain
MHKHGFKK_00050 4.1e-79 S Uncharacterised protein family UPF0047
MHKHGFKK_00051 9.2e-98 tpiA 5.3.1.1 G triosephosphate isomerase
MHKHGFKK_00052 5e-79 4.1.2.13 G aldolase
MHKHGFKK_00053 2.5e-30 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MHKHGFKK_00054 9.7e-186 G PTS system sugar-specific permease component
MHKHGFKK_00055 8.5e-33 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHKHGFKK_00056 3.2e-16 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHKHGFKK_00057 2.3e-119 manR K PRD domain
MHKHGFKK_00058 7.6e-166 S Nuclease-related domain
MHKHGFKK_00059 6.4e-207 L Transposase IS4 family protein
MHKHGFKK_00060 2.5e-166 araC1 K AraC-like ligand binding domain
MHKHGFKK_00061 1.1e-278 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MHKHGFKK_00062 9.7e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MHKHGFKK_00063 1.7e-159 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 G Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
MHKHGFKK_00064 3.2e-32 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C hydroxyacid-oxoacid transhydrogenase activity
MHKHGFKK_00065 1.1e-74 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MHKHGFKK_00066 4.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHKHGFKK_00067 3.3e-226 EGP Major facilitator Superfamily
MHKHGFKK_00068 2e-253 lmrB EGP the major facilitator superfamily
MHKHGFKK_00069 8.4e-99 yxaF_1 K Transcriptional regulator
MHKHGFKK_00070 2.5e-103 yyaR K Acetyltransferase (GNAT) domain
MHKHGFKK_00071 3e-191 S AI-2E family transporter
MHKHGFKK_00072 7e-161 S hydrolases of the HAD superfamily
MHKHGFKK_00073 6.7e-125 L Transposase, IS4 family protein
MHKHGFKK_00074 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHKHGFKK_00075 6.8e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MHKHGFKK_00076 1.1e-110 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHKHGFKK_00077 2.1e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MHKHGFKK_00078 4e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MHKHGFKK_00079 6.7e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHKHGFKK_00080 1.8e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MHKHGFKK_00081 4.9e-213 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHKHGFKK_00082 8.6e-219 pbuO_1 S permease
MHKHGFKK_00083 1.8e-116 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MHKHGFKK_00084 8e-166 S Protein of unknown function (DUF979)
MHKHGFKK_00085 6.5e-117 S Protein of unknown function (DUF969)
MHKHGFKK_00086 2.6e-135 ycsF S Belongs to the UPF0271 (lamB) family
MHKHGFKK_00087 1.2e-180 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MHKHGFKK_00088 6.6e-133 kipI 3.5.1.54, 6.3.4.6 E Allophanate hydrolase subunit 1
MHKHGFKK_00089 9.3e-212 EGP Major facilitator Superfamily
MHKHGFKK_00090 1.3e-78 ymaD O redox protein, regulator of disulfide bond formation
MHKHGFKK_00091 3.7e-131 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MHKHGFKK_00092 7.6e-115 artQ E COG0765 ABC-type amino acid transport system, permease component
MHKHGFKK_00093 2e-135 artP ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MHKHGFKK_00094 2.3e-215 hipO3 3.5.1.47 S amidohydrolase
MHKHGFKK_00095 0.0 htpG O Molecular chaperone. Has ATPase activity
MHKHGFKK_00096 4.8e-207 M FFAT motif binding
MHKHGFKK_00097 2.8e-57 I Domain of unknown function (DUF4430)
MHKHGFKK_00098 3.7e-94 S Psort location CytoplasmicMembrane, score
MHKHGFKK_00099 4.3e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MHKHGFKK_00100 3.8e-113 crtF 2.1.1.210, 2.1.1.281, 2.1.1.79 M Methyltransferase
MHKHGFKK_00101 2.9e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MHKHGFKK_00102 4.3e-37 S Protein of unknown function DUF86
MHKHGFKK_00103 4.5e-55 S Nucleotidyltransferase domain
MHKHGFKK_00104 1.2e-191 adhP 1.1.1.1 C alcohol dehydrogenase
MHKHGFKK_00106 4.1e-83 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKHGFKK_00107 2.7e-40 S Protein of unknown function (DUF2750)
MHKHGFKK_00108 1.4e-10 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MHKHGFKK_00110 6.5e-112 EGP Major facilitator Superfamily
MHKHGFKK_00111 8.5e-142 IQ Enoyl-(Acyl carrier protein) reductase
MHKHGFKK_00112 5.5e-147 S Protein of unknown function
MHKHGFKK_00113 2.3e-141 S Protein of unknown function (DUF2961)
MHKHGFKK_00114 3.6e-65
MHKHGFKK_00115 2.1e-300 lmrA 3.6.3.44 V ABC transporter
MHKHGFKK_00116 2.8e-100 K Iron dependent repressor, N-terminal DNA binding domain
MHKHGFKK_00117 4.9e-41
MHKHGFKK_00118 7.5e-258 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHKHGFKK_00119 1.3e-154 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MHKHGFKK_00120 2.4e-147 pdaA G deacetylase
MHKHGFKK_00121 3e-27 yfjT
MHKHGFKK_00122 1.5e-146 yfkD S YfkD-like protein
MHKHGFKK_00123 1.5e-173 cax P COG0387 Ca2 H antiporter
MHKHGFKK_00124 3.1e-220 yfkF EGP Major facilitator Superfamily
MHKHGFKK_00125 1.4e-145 yihY S Belongs to the UPF0761 family
MHKHGFKK_00126 2.1e-32 yfkK S Belongs to the UPF0435 family
MHKHGFKK_00127 4.9e-142 map 3.4.11.18 E Methionine aminopeptidase
MHKHGFKK_00128 4.6e-91 yfkM 3.5.1.124 S protease
MHKHGFKK_00129 5.5e-123 motB N Flagellar motor protein
MHKHGFKK_00130 9.5e-136 motA N flagellar motor
MHKHGFKK_00131 6.7e-57 yhdN S Domain of unknown function (DUF1992)
MHKHGFKK_00132 3.7e-60 yeaO S Protein of unknown function, DUF488
MHKHGFKK_00133 1.8e-229 EGP Major facilitator Superfamily
MHKHGFKK_00134 2.6e-143 dksA T COG1734 DnaK suppressor protein
MHKHGFKK_00135 3.7e-85 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MHKHGFKK_00136 9.9e-183 mreB D Rod-share determining protein MreBH
MHKHGFKK_00137 6.7e-167 yuaG S protein conserved in bacteria
MHKHGFKK_00138 9.3e-90 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MHKHGFKK_00139 6.7e-212 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MHKHGFKK_00140 5.1e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MHKHGFKK_00141 6.2e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHKHGFKK_00142 1.6e-117 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MHKHGFKK_00143 2.8e-102 4.2.1.1 P Reversible hydration of carbon dioxide
MHKHGFKK_00145 3.1e-127 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MHKHGFKK_00147 1.4e-297 K helix_turn_helix, Lux Regulon
MHKHGFKK_00148 3.2e-99 che
MHKHGFKK_00149 3.4e-68 S response to pH
MHKHGFKK_00150 4.6e-99
MHKHGFKK_00151 5.7e-161 ypuA S Secreted protein
MHKHGFKK_00152 5.3e-153 K RpiR family transcriptional regulator
MHKHGFKK_00153 1e-220 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MHKHGFKK_00154 1.6e-225 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHKHGFKK_00155 1.7e-116 cobC 3.1.3.3, 3.1.3.73, 5.4.2.12 G Histidine phosphatase superfamily (branch 1)
MHKHGFKK_00156 1.2e-70 K Transcriptional
MHKHGFKK_00157 4.4e-39 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHKHGFKK_00158 1.7e-161 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHKHGFKK_00159 1.3e-98 cas4 3.1.12.1 L RecB family exonuclease
MHKHGFKK_00160 4.3e-134 csd2 L CRISPR-associated protein
MHKHGFKK_00161 9e-270 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
MHKHGFKK_00162 3.1e-114 cas5d S CRISPR-associated protein (Cas_Cas5)
MHKHGFKK_00163 0.0 cas3 L Metal dependent phosphohydrolases with conserved 'HD' motif.
MHKHGFKK_00164 2.1e-299 dppE_1 E ABC transporter substrate-binding protein
MHKHGFKK_00165 1.9e-143 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHKHGFKK_00166 1.3e-182 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHKHGFKK_00167 1.6e-194 oppD P Belongs to the ABC transporter superfamily
MHKHGFKK_00168 8.7e-173 oppF E Belongs to the ABC transporter superfamily
MHKHGFKK_00169 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHKHGFKK_00170 6e-120 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHKHGFKK_00171 2.2e-240 yjbF S Competence protein
MHKHGFKK_00172 0.0 pepF E oligoendopeptidase F
MHKHGFKK_00173 9.7e-91 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
MHKHGFKK_00174 5.2e-141 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MHKHGFKK_00175 4.8e-166 yocS S -transporter
MHKHGFKK_00176 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MHKHGFKK_00177 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MHKHGFKK_00178 2.1e-152 yicC S stress-induced protein
MHKHGFKK_00179 6.5e-45 ylzA S Belongs to the UPF0296 family
MHKHGFKK_00180 1.3e-108 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MHKHGFKK_00181 3.4e-29 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHKHGFKK_00182 4.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHKHGFKK_00183 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHKHGFKK_00184 8.1e-82 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHKHGFKK_00185 5.3e-178 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHKHGFKK_00186 2.2e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHKHGFKK_00187 7.8e-140 stp 3.1.3.16 T phosphatase
MHKHGFKK_00188 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MHKHGFKK_00189 8.8e-167 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHKHGFKK_00190 5.9e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MHKHGFKK_00191 2.8e-125 thiN 2.7.6.2 H thiamine pyrophosphokinase
MHKHGFKK_00192 5e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MHKHGFKK_00193 1.5e-59 asp S protein conserved in bacteria
MHKHGFKK_00194 1.5e-305 yloV S kinase related to dihydroxyacetone kinase
MHKHGFKK_00195 9.6e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MHKHGFKK_00196 1.3e-154 sdaAA 4.3.1.17 E L-serine dehydratase
MHKHGFKK_00197 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHKHGFKK_00198 7.4e-98 fapR 5.3.1.23 Q Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MHKHGFKK_00199 7.8e-208 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHKHGFKK_00200 2.1e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MHKHGFKK_00201 1.8e-128 IQ reductase
MHKHGFKK_00202 3.7e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHKHGFKK_00203 4.5e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHKHGFKK_00204 0.0 smc D Required for chromosome condensation and partitioning
MHKHGFKK_00205 2.5e-178 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHKHGFKK_00206 2.6e-52 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHKHGFKK_00207 5.1e-243 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHKHGFKK_00208 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MHKHGFKK_00209 4.7e-35 ylqC S Belongs to the UPF0109 family
MHKHGFKK_00210 8.3e-61 ylqD S YlqD protein
MHKHGFKK_00211 1.7e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHKHGFKK_00212 8.9e-141 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MHKHGFKK_00213 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHKHGFKK_00214 1.6e-102 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MHKHGFKK_00215 2.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHKHGFKK_00216 8.7e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHKHGFKK_00217 4.4e-233 CP_1081 D nuclear chromosome segregation
MHKHGFKK_00218 3.6e-45 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MHKHGFKK_00219 2.1e-213 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MHKHGFKK_00220 2.8e-168 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MHKHGFKK_00221 6.2e-165 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MHKHGFKK_00222 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHKHGFKK_00224 5.1e-170 xerC L tyrosine recombinase XerC
MHKHGFKK_00225 2.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHKHGFKK_00226 5.1e-225 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHKHGFKK_00227 8.6e-134 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MHKHGFKK_00228 2.8e-61 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MHKHGFKK_00229 4e-75 flgC N Belongs to the flagella basal body rod proteins family
MHKHGFKK_00230 9.9e-41 fliE N Flagellar hook-basal body complex protein FliE
MHKHGFKK_00231 1.6e-248 fliF N The M ring may be actively involved in energy transduction
MHKHGFKK_00232 2.2e-207 comM O Mg chelatase subunit ChlI
MHKHGFKK_00233 1.1e-149 S transposase or invertase
MHKHGFKK_00234 4.6e-21
MHKHGFKK_00235 3.3e-200 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
MHKHGFKK_00236 2.4e-248 csbC EGP Major facilitator Superfamily
MHKHGFKK_00237 8.9e-292 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
MHKHGFKK_00238 1.7e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MHKHGFKK_00239 7.2e-217 xylR GK ROK family
MHKHGFKK_00240 3.1e-206 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MHKHGFKK_00241 3.8e-159 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MHKHGFKK_00242 8.3e-301 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MHKHGFKK_00243 2.8e-210 nifS 2.8.1.7 E Cysteine desulfurase
MHKHGFKK_00244 3.2e-95 S NYN domain
MHKHGFKK_00245 1.2e-143 focA P Formate nitrite
MHKHGFKK_00246 5.8e-265 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MHKHGFKK_00247 7.6e-144 cbiQ P COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
MHKHGFKK_00248 0.0 ykoD P ABC transporter, ATP-binding protein
MHKHGFKK_00249 2e-92 S UPF0397 protein
MHKHGFKK_00250 1.1e-163 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
MHKHGFKK_00251 1.5e-122 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MHKHGFKK_00252 4.1e-251 EG COG2610 H gluconate symporter and related permeases
MHKHGFKK_00253 2.9e-284 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHKHGFKK_00254 3.3e-217 adhB 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
MHKHGFKK_00255 0.0 KT Transcriptional regulator
MHKHGFKK_00256 0.0 xylS 3.2.1.20 GH31 G Domain of unknown function (DUF5110)
MHKHGFKK_00257 3.6e-281 Otg1 S Predicted membrane protein (DUF2339)
MHKHGFKK_00258 2.1e-229 1.3.8.7 I Acyl-CoA dehydrogenase, N-terminal domain
MHKHGFKK_00259 2.5e-283 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MHKHGFKK_00260 1.5e-194 S Metallo-beta-lactamase superfamily
MHKHGFKK_00261 8.2e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MHKHGFKK_00262 3e-134 phnE 3.6.1.63 P ABC transporter
MHKHGFKK_00263 6.1e-143 phnE 3.6.1.63 P ABC transporter
MHKHGFKK_00264 1.1e-175 phnD P Phosphonate ABC transporter
MHKHGFKK_00265 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MHKHGFKK_00266 2.1e-207 ysdC G COG1363 Cellulase M and related proteins
MHKHGFKK_00268 2.6e-35
MHKHGFKK_00269 2.9e-144 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MHKHGFKK_00270 1.9e-18
MHKHGFKK_00271 1.2e-15
MHKHGFKK_00272 2.7e-53 S Domain of unknown function (DUF5085)
MHKHGFKK_00273 8.6e-147 yjbA S Belongs to the UPF0736 family
MHKHGFKK_00274 1e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MHKHGFKK_00275 2.7e-47 S Domain of unknown function (DUF3899)
MHKHGFKK_00276 6.4e-145 hel M 5'-nucleotidase, lipoprotein e(P4)
MHKHGFKK_00279 6.1e-213 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MHKHGFKK_00280 1.1e-12
MHKHGFKK_00281 2.3e-223 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHKHGFKK_00282 1.7e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MHKHGFKK_00283 8.6e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MHKHGFKK_00284 1.9e-200 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
MHKHGFKK_00285 1.8e-181 K Transcriptional regulator
MHKHGFKK_00286 5.1e-32 S Cold-inducible protein YdjO
MHKHGFKK_00287 1.5e-14
MHKHGFKK_00289 9.7e-163 cvfB S protein conserved in bacteria
MHKHGFKK_00290 1.3e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHKHGFKK_00291 1.1e-08 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHKHGFKK_00292 2.1e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
MHKHGFKK_00293 1.4e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MHKHGFKK_00295 3.4e-272 yusP P Major facilitator superfamily
MHKHGFKK_00296 6.7e-212 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHKHGFKK_00297 3.6e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHKHGFKK_00298 1e-125 gntR1 K transcriptional
MHKHGFKK_00299 4.4e-188 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MHKHGFKK_00300 1.1e-246 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MHKHGFKK_00301 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MHKHGFKK_00302 4.6e-167 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MHKHGFKK_00303 2.8e-114 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MHKHGFKK_00304 6.9e-204 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MHKHGFKK_00305 2.4e-124 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHKHGFKK_00306 2.2e-260 yfnA E amino acid
MHKHGFKK_00307 2.8e-154 degV S protein conserved in bacteria
MHKHGFKK_00309 1.4e-267 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MHKHGFKK_00310 3e-133 comFC S Phosphoribosyl transferase domain
MHKHGFKK_00311 4.4e-70 yvyF S flagellar protein
MHKHGFKK_00312 6.1e-39 flgM KNU Negative regulator of flagellin synthesis
MHKHGFKK_00313 2.6e-77 flgN NOU FlgN protein
MHKHGFKK_00314 8.4e-293 flgK N flagellar hook-associated protein
MHKHGFKK_00315 5.2e-159 flgL N Belongs to the bacterial flagellin family
MHKHGFKK_00316 6.4e-81 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MHKHGFKK_00317 1.6e-33 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MHKHGFKK_00318 1.3e-22 S Nucleotidyltransferase domain
MHKHGFKK_00319 9.6e-100 secA U SEC-C motif
MHKHGFKK_00320 9.1e-170 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MHKHGFKK_00322 3.3e-168 E COG1113 Gamma-aminobutyrate permease and related permeases
MHKHGFKK_00323 0.0 ycbZ 3.4.21.53 O AAA domain
MHKHGFKK_00325 2.9e-105 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MHKHGFKK_00327 8.7e-60 flaG N flagellar protein FlaG
MHKHGFKK_00328 7.5e-225 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MHKHGFKK_00329 3.9e-69 fliS N flagellar protein FliS
MHKHGFKK_00330 1.1e-56 fliT S bacterial-type flagellum organization
MHKHGFKK_00331 2.7e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHKHGFKK_00332 1.3e-298 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MHKHGFKK_00333 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHKHGFKK_00334 1.1e-170 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHKHGFKK_00335 2.1e-157 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MHKHGFKK_00336 2.9e-51 cccB C COG2010 Cytochrome c, mono- and diheme variants
MHKHGFKK_00338 1.4e-136 ftsE D cell division ATP-binding protein FtsE
MHKHGFKK_00339 1.4e-156 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MHKHGFKK_00340 2.6e-93 D peptidase
MHKHGFKK_00341 9.3e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHKHGFKK_00342 1.3e-248 metY 2.5.1.49 E O-acetylhomoserine
MHKHGFKK_00343 3.7e-182 1.1.1.3 E homoserine dehydrogenase
MHKHGFKK_00344 7.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MHKHGFKK_00345 2e-222 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHKHGFKK_00346 3.6e-166 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKHGFKK_00347 1.8e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKHGFKK_00348 3.6e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MHKHGFKK_00349 1.1e-178 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MHKHGFKK_00350 2.1e-41 fdxA C 4Fe-4S binding domain
MHKHGFKK_00351 4.5e-46 S Family of unknown function (DUF5316)
MHKHGFKK_00352 1.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKHGFKK_00353 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MHKHGFKK_00354 1.2e-20 phoR 2.7.13.3 T Signal transduction histidine kinase
MHKHGFKK_00355 3.6e-263 hemY2 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MHKHGFKK_00356 4.7e-160 pstS P Phosphate
MHKHGFKK_00357 7.5e-164 pstC P probably responsible for the translocation of the substrate across the membrane
MHKHGFKK_00358 8.2e-157 pstA P Phosphate transport system permease
MHKHGFKK_00359 7.2e-155 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHKHGFKK_00360 2e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHKHGFKK_00362 4.6e-174 M Glycosyltransferase like family 2
MHKHGFKK_00363 0.0
MHKHGFKK_00364 7.8e-58 P EamA-like transporter family
MHKHGFKK_00365 8.6e-51 S EamA-like transporter family
MHKHGFKK_00366 1.4e-118 yfbR S HD containing hydrolase-like enzyme
MHKHGFKK_00367 2.7e-33 csbA S protein conserved in bacteria
MHKHGFKK_00368 1.6e-09 S Uncharacterized conserved protein (DUF2164)
MHKHGFKK_00369 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHKHGFKK_00370 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHKHGFKK_00371 2.8e-72 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MHKHGFKK_00372 4.3e-225 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHKHGFKK_00373 1.1e-144 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MHKHGFKK_00374 5.7e-161 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHKHGFKK_00375 2.8e-232 tagF 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHKHGFKK_00376 0.0 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHKHGFKK_00377 1.3e-145 tagG GM Transport permease protein
MHKHGFKK_00378 1.1e-228 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHKHGFKK_00379 1.1e-169 yvlB S Putative adhesin
MHKHGFKK_00380 5.5e-32 yvlD S Membrane
MHKHGFKK_00381 8e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHKHGFKK_00382 1.3e-153 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHKHGFKK_00383 3.5e-120 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MHKHGFKK_00384 1.5e-73 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MHKHGFKK_00385 1.6e-264 S COG0457 FOG TPR repeat
MHKHGFKK_00386 5.9e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHKHGFKK_00387 3e-86 yvcI 3.6.1.55 F Nudix hydrolase
MHKHGFKK_00388 1.4e-167 rapZ S Displays ATPase and GTPase activities
MHKHGFKK_00389 2e-180 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MHKHGFKK_00390 3e-173 whiA K May be required for sporulation
MHKHGFKK_00391 4.3e-40 crh G Phosphocarrier protein Chr
MHKHGFKK_00392 2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHKHGFKK_00394 1.5e-148 S transposase or invertase
MHKHGFKK_00395 1.8e-14 S transposase or invertase
MHKHGFKK_00396 7.8e-263 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHKHGFKK_00397 3.4e-29 sspB S spore protein
MHKHGFKK_00398 6.9e-206 msmK P Belongs to the ABC transporter superfamily
MHKHGFKK_00399 9.1e-164 lrp QT PucR C-terminal helix-turn-helix domain
MHKHGFKK_00400 4.1e-228 HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
MHKHGFKK_00401 3.2e-269 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MHKHGFKK_00402 1.3e-212 yheC HJ YheC/D like ATP-grasp
MHKHGFKK_00403 2.8e-257 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MHKHGFKK_00404 4.5e-208 yheB S Belongs to the UPF0754 family
MHKHGFKK_00405 5.1e-54 yheA S Belongs to the UPF0342 family
MHKHGFKK_00406 1.2e-160 yhaX S hydrolases of the HAD superfamily
MHKHGFKK_00407 1.2e-138 yhaR 5.3.3.18 I enoyl-CoA hydratase
MHKHGFKK_00408 2.9e-27 S YhzD-like protein
MHKHGFKK_00409 1.8e-123 P Integral membrane protein TerC family
MHKHGFKK_00411 1.6e-158 ycgR S permeases
MHKHGFKK_00412 2.8e-162 ycgQ S membrane
MHKHGFKK_00413 2.8e-240 yhaO L DNA repair exonuclease
MHKHGFKK_00414 0.0 L AAA domain
MHKHGFKK_00415 3.7e-179 yhaM L Shows a 3'-5' exoribonuclease activity
MHKHGFKK_00416 3e-27 yhaL S Sporulation protein YhaL
MHKHGFKK_00417 4.9e-154 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHKHGFKK_00418 1.1e-53 yhaI S Protein of unknown function (DUF1878)
MHKHGFKK_00419 5.2e-104 hpr K Negative regulator of protease production and sporulation
MHKHGFKK_00420 2.5e-18 yhaH S YtxH-like protein
MHKHGFKK_00421 1.1e-84 trpP S Tryptophan transporter TrpP
MHKHGFKK_00422 4.1e-74 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MHKHGFKK_00423 7.2e-138 ecsA V transporter (ATP-binding protein)
MHKHGFKK_00424 1e-218 ecsB U ABC transporter
MHKHGFKK_00425 3.6e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MHKHGFKK_00426 1.1e-235 yhfA C membrane
MHKHGFKK_00427 3e-95 traP 1.14.99.57 S enzyme involved in biosynthesis of extracellular polysaccharides
MHKHGFKK_00428 5.1e-198 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MHKHGFKK_00429 8.5e-184 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MHKHGFKK_00430 3.1e-270 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MHKHGFKK_00431 6e-100 yhgD K Transcriptional regulator
MHKHGFKK_00432 3.4e-190 yhgE S YhgE Pip N-terminal domain protein
MHKHGFKK_00433 1.4e-165 arbF1 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
MHKHGFKK_00434 5.1e-131 ydjF K DeoR C terminal sensor domain
MHKHGFKK_00435 5.5e-12 iolF EGP Major facilitator Superfamily
MHKHGFKK_00436 5.7e-71 EGP Major facilitator Superfamily
MHKHGFKK_00437 1.5e-164 EG EamA-like transporter family
MHKHGFKK_00438 1.6e-129 aldA 1.2.1.21, 1.2.1.22 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHKHGFKK_00439 6.7e-104 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MHKHGFKK_00440 1.2e-64 ytkA S YtkA-like
MHKHGFKK_00441 8e-22 yhfH S YhfH-like protein
MHKHGFKK_00442 1.6e-185 lplJ 6.3.1.20 H Lipoate-protein ligase
MHKHGFKK_00443 3.2e-297 fadD 6.2.1.3 IQ Activates fatty acids by binding to coenzyme A
MHKHGFKK_00444 1.1e-119 azlC E AzlC protein
MHKHGFKK_00445 6.7e-42 azlD S branched-chain amino acid
MHKHGFKK_00446 1.9e-220 yhfN 3.4.24.84 O Peptidase M48
MHKHGFKK_00447 3.4e-09 S IDEAL
MHKHGFKK_00448 1.8e-98 comK K Competence transcription factor
MHKHGFKK_00449 1.7e-145 S Mitochondrial biogenesis AIM24
MHKHGFKK_00451 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MHKHGFKK_00452 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MHKHGFKK_00453 4.2e-30 gerPF S Spore germination protein gerPA/gerPF
MHKHGFKK_00454 3.4e-71 gerPE S Spore germination protein GerPE
MHKHGFKK_00455 2e-25 gerPD S Spore germination protein
MHKHGFKK_00456 1.2e-98 gerPC S Spore germination protein
MHKHGFKK_00457 1.6e-32 gerPA S Spore germination protein
MHKHGFKK_00458 5.1e-223 P Protein of unknown function (DUF418)
MHKHGFKK_00459 5.3e-164 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MHKHGFKK_00460 5.1e-60 yisL S UPF0344 protein
MHKHGFKK_00461 6.2e-102 yisN S Protein of unknown function (DUF2777)
MHKHGFKK_00462 1.9e-158 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKHGFKK_00464 7e-161 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MHKHGFKK_00465 1.4e-74 yjbI S COG2346 Truncated hemoglobins
MHKHGFKK_00466 1.4e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHKHGFKK_00467 4.4e-106 yjbK S protein conserved in bacteria
MHKHGFKK_00468 1.2e-56 yjbL S Belongs to the UPF0738 family
MHKHGFKK_00469 3.8e-122 yjbM 2.7.6.5 S GTP pyrophosphokinase
MHKHGFKK_00470 4.9e-153 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHKHGFKK_00471 4.9e-162 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MHKHGFKK_00472 5.6e-143 prpE 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MHKHGFKK_00473 3.3e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MHKHGFKK_00476 1.2e-84 cotY S Spore coat protein
MHKHGFKK_00477 8.4e-60 S Protein of unknown function (DUF1360)
MHKHGFKK_00479 1.9e-80 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHKHGFKK_00480 1.5e-83 spoVAC S stage V sporulation protein AC
MHKHGFKK_00481 3.4e-191 spoVAD I Stage V sporulation protein AD
MHKHGFKK_00482 8.7e-57 spoVAE S stage V sporulation protein
MHKHGFKK_00484 4.5e-39 spoVIF S Stage VI sporulation protein F
MHKHGFKK_00486 3.8e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHKHGFKK_00487 1.5e-94 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MHKHGFKK_00488 1.8e-141 yjcH P COG2382 Enterochelin esterase and related enzymes
MHKHGFKK_00496 3.5e-168 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MHKHGFKK_00497 7.3e-169 yhaQ S ABC transporter, ATP-binding protein
MHKHGFKK_00498 3.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MHKHGFKK_00499 2.4e-261 pepC 3.4.22.40 E Papain family cysteine protease
MHKHGFKK_00500 2.7e-31 S Domain of unknown function (DUF4177)
MHKHGFKK_00501 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MHKHGFKK_00502 1.4e-153 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHKHGFKK_00503 5.5e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHKHGFKK_00504 8.9e-109 pncA Q COG1335 Amidases related to nicotinamidase
MHKHGFKK_00505 4.7e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MHKHGFKK_00506 0.0 ykoS
MHKHGFKK_00507 4.3e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MHKHGFKK_00508 2e-67 yngA S GtrA-like protein
MHKHGFKK_00509 5.3e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHKHGFKK_00510 9.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHKHGFKK_00511 8.1e-126 ydiL S CAAX protease self-immunity
MHKHGFKK_00512 4.7e-28 S Domain of unknown function (DUF4305)
MHKHGFKK_00513 5.1e-131 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MHKHGFKK_00514 2.7e-123 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHKHGFKK_00515 1.6e-08 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHKHGFKK_00516 0.0 ydiF S ABC transporter
MHKHGFKK_00517 7e-08 ydiF S ABC transporter
MHKHGFKK_00518 8.9e-184 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHKHGFKK_00519 4.5e-82 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MHKHGFKK_00520 5.7e-129 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MHKHGFKK_00521 9e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MHKHGFKK_00523 4.7e-13
MHKHGFKK_00524 4.1e-82 S cellulose binding
MHKHGFKK_00525 3.3e-217 G Major facilitator Superfamily
MHKHGFKK_00526 1.5e-83 S Pfam:DUF1399
MHKHGFKK_00527 4.3e-127 EGP Major facilitator Superfamily
MHKHGFKK_00528 9.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MHKHGFKK_00529 3.5e-260 NT Chemoreceptor zinc-binding domain
MHKHGFKK_00530 8.3e-114 S Putative adhesin
MHKHGFKK_00531 3.9e-96 S Protein of unknown function (DUF1700)
MHKHGFKK_00532 1.3e-54 K PadR family transcriptional regulator
MHKHGFKK_00533 2e-183 NT chemotaxis protein
MHKHGFKK_00534 7.4e-253 EGP Major facilitator superfamily
MHKHGFKK_00535 1.3e-102 Q Isochorismatase family
MHKHGFKK_00536 1.1e-107 K Transcriptional regulator
MHKHGFKK_00537 6.4e-60
MHKHGFKK_00538 6e-127
MHKHGFKK_00539 5.2e-44 ltaA 4.1.2.48 E L-allo-threonine aldolase activity
MHKHGFKK_00540 5.5e-209 EGP Major Facilitator Superfamily
MHKHGFKK_00541 3.9e-170 F ATP-grasp domain
MHKHGFKK_00542 1.6e-07 F ATP-grasp domain
MHKHGFKK_00543 3.2e-211 K helix_turn_helix, Arsenical Resistance Operon Repressor
MHKHGFKK_00544 1.7e-51 ykvR S Protein of unknown function (DUF3219)
MHKHGFKK_00545 7.2e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHKHGFKK_00547 1.2e-217 yjbB G Major Facilitator Superfamily
MHKHGFKK_00549 3.4e-97 rimJ 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHKHGFKK_00551 1.1e-86 2.3.1.128 J Acetyltransferase (GNAT) domain
MHKHGFKK_00552 1.9e-40 L PFAM Transposase, IS4-like
MHKHGFKK_00553 2.1e-70 yxiE T Belongs to the universal stress protein A family
MHKHGFKK_00554 8.4e-28
MHKHGFKK_00555 3.3e-69
MHKHGFKK_00556 1.1e-225 yfkA S YfkB-like domain
MHKHGFKK_00558 3.1e-286 K NB-ARC domain
MHKHGFKK_00559 5e-201 gutB 1.1.1.14 E Dehydrogenase
MHKHGFKK_00560 6.3e-91 gutA G MFS/sugar transport protein
MHKHGFKK_00561 6.6e-90 gutA G MFS/sugar transport protein
MHKHGFKK_00562 1.3e-176 ykvZ 5.1.1.1 K Transcriptional regulator
MHKHGFKK_00563 5.1e-93 hxlB 4.1.2.43, 5.3.1.27 M arabinose-5-phosphate isomerase activity
MHKHGFKK_00564 1.4e-147 ykrA S hydrolases of the HAD superfamily
MHKHGFKK_00566 1e-147 yvaK 3.1.1.1 S BAAT / Acyl-CoA thioester hydrolase C terminal
MHKHGFKK_00567 9.6e-149 L COG2801 Transposase and inactivated derivatives
MHKHGFKK_00568 3.7e-45 L COG2963 Transposase and inactivated derivatives
MHKHGFKK_00569 1.8e-113 M Spore coat protein
MHKHGFKK_00570 6.1e-137 I alpha/beta hydrolase fold
MHKHGFKK_00571 2.1e-154 S Aldo/keto reductase family
MHKHGFKK_00572 3.6e-97 1.5.1.38 S FMN reductase
MHKHGFKK_00573 3.8e-248 yhaO L Calcineurin-like phosphoesterase superfamily domain
MHKHGFKK_00574 0.0 L AAA domain
MHKHGFKK_00575 6.5e-154 mmgB 1.1.1.157 I Dehydrogenase
MHKHGFKK_00576 8.2e-244 yeeO V Mate efflux family protein
MHKHGFKK_00577 4.5e-65 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
MHKHGFKK_00578 1.4e-50 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MHKHGFKK_00579 6.3e-111 yhbD K Protein of unknown function (DUF4004)
MHKHGFKK_00580 1e-223 yhdR 2.6.1.1 E Aminotransferase
MHKHGFKK_00581 9.6e-104 proA_2 H Methyltransferase
MHKHGFKK_00582 0.0 rafA 3.2.1.22 G Alpha-galactosidase
MHKHGFKK_00583 2.2e-51 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHKHGFKK_00584 8.1e-268 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHKHGFKK_00585 3.4e-146 ubiE Q Methyltransferase type 11
MHKHGFKK_00586 7e-206 M Glycosyl hydrolases family 25
MHKHGFKK_00587 3e-79
MHKHGFKK_00588 6.7e-136 IQ Short-chain dehydrogenase reductase sdr
MHKHGFKK_00589 4.9e-235 cshA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MHKHGFKK_00590 5.9e-135 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MHKHGFKK_00591 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
MHKHGFKK_00593 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MHKHGFKK_00594 1.9e-247 hisS 6.1.1.21 J histidyl-tRNA synthetase
MHKHGFKK_00596 4.7e-266 lytH 3.5.1.28, 6.1.1.12 M COG3103 SH3 domain protein
MHKHGFKK_00597 0.0 yhcA5 EGP Major facilitator Superfamily
MHKHGFKK_00598 1.2e-107 emrA V Barrel-sandwich domain of CusB or HlyD membrane-fusion
MHKHGFKK_00599 9e-72 K helix_turn_helix multiple antibiotic resistance protein
MHKHGFKK_00600 2.1e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHKHGFKK_00601 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHKHGFKK_00602 9e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHKHGFKK_00603 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MHKHGFKK_00604 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MHKHGFKK_00605 1.2e-54 yrzD S Post-transcriptional regulator
MHKHGFKK_00606 3.8e-274 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHKHGFKK_00607 9.5e-110 yrbG S membrane
MHKHGFKK_00608 1.4e-63 yrzE S Protein of unknown function (DUF3792)
MHKHGFKK_00609 8.7e-51 yajC U Preprotein translocase subunit YajC
MHKHGFKK_00610 5.3e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHKHGFKK_00611 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MHKHGFKK_00612 3.2e-27 yrzS S Protein of unknown function (DUF2905)
MHKHGFKK_00613 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHKHGFKK_00614 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHKHGFKK_00615 5.5e-127 yebC K transcriptional regulatory protein
MHKHGFKK_00616 8.9e-189 1.1.1.34, 2.7.1.89 M choline kinase involved in LPS biosynthesis
MHKHGFKK_00617 9.7e-135 safA M spore coat assembly protein SafA
MHKHGFKK_00618 3.3e-95 niaR S small molecule binding protein (contains 3H domain)
MHKHGFKK_00619 1.1e-158 pheA 4.2.1.51 E Prephenate dehydratase
MHKHGFKK_00620 1.2e-74 pheB 5.4.99.5 S Belongs to the UPF0735 family
MHKHGFKK_00621 9.9e-244 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHKHGFKK_00622 3e-98 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MHKHGFKK_00623 1.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MHKHGFKK_00624 1.7e-51 ysxB J ribosomal protein
MHKHGFKK_00625 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
MHKHGFKK_00626 1e-276 rng J ribonuclease, Rne Rng family
MHKHGFKK_00627 9.8e-163 spoIVFB S Stage IV sporulation protein
MHKHGFKK_00628 3.4e-135 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MHKHGFKK_00629 1e-145 minD D Belongs to the ParA family
MHKHGFKK_00630 3.3e-121 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MHKHGFKK_00631 6.9e-87 mreD M shape-determining protein
MHKHGFKK_00632 4.4e-139 mreC M Involved in formation and maintenance of cell shape
MHKHGFKK_00633 6.9e-184 mreB D Rod shape-determining protein MreB
MHKHGFKK_00634 1.9e-121 radC E Belongs to the UPF0758 family
MHKHGFKK_00635 3.7e-166 spoIIB
MHKHGFKK_00636 5.1e-131 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MHKHGFKK_00637 1e-101
MHKHGFKK_00638 6.2e-80 pilN NU PFAM Fimbrial assembly family protein
MHKHGFKK_00639 2.3e-192 NU COG4972 Tfp pilus assembly protein, ATPase PilM
MHKHGFKK_00640 6e-44 NU cell adhesion
MHKHGFKK_00641 7.9e-203 pilC NU type II secretion system
MHKHGFKK_00642 1.5e-194 pilT NU twitching motility protein
MHKHGFKK_00643 5.6e-292 pilB NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MHKHGFKK_00644 5.2e-217 V G5
MHKHGFKK_00645 5e-128 S PRC-barrel domain
MHKHGFKK_00646 8.5e-198
MHKHGFKK_00647 6.1e-214 NU Pilus assembly protein PilX
MHKHGFKK_00648 4.8e-85
MHKHGFKK_00650 2.1e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MHKHGFKK_00651 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHKHGFKK_00652 9.5e-26
MHKHGFKK_00653 1.7e-226 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MHKHGFKK_00654 2.6e-180 spoVID M stage VI sporulation protein D
MHKHGFKK_00655 1.9e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MHKHGFKK_00656 1.3e-184 hemB 4.2.1.24 H Belongs to the ALAD family
MHKHGFKK_00657 3e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MHKHGFKK_00658 3.5e-166 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MHKHGFKK_00659 4.2e-147 hemX O cytochrome C
MHKHGFKK_00660 2.3e-240 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MHKHGFKK_00661 4.5e-88 ysxD
MHKHGFKK_00662 4.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MHKHGFKK_00663 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MHKHGFKK_00664 9.7e-305 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MHKHGFKK_00665 1.7e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHKHGFKK_00666 2.1e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHKHGFKK_00667 2.2e-182 trxA2 O COG0457 FOG TPR repeat
MHKHGFKK_00668 1.1e-72 S Protein of unknown function (DUF2512)
MHKHGFKK_00669 9.8e-46
MHKHGFKK_00671 6.3e-93 ysnB S Phosphoesterase
MHKHGFKK_00672 1.7e-105 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MHKHGFKK_00673 1e-190 gerM S COG5401 Spore germination protein
MHKHGFKK_00674 1.8e-14
MHKHGFKK_00675 2.3e-42 M Spore coat protein
MHKHGFKK_00676 4.3e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHKHGFKK_00677 7.8e-61 yraF M Spore coat protein
MHKHGFKK_00678 8.4e-31 yraG S Spore Coat Protein
MHKHGFKK_00679 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MHKHGFKK_00680 3.9e-78 ysmB 2.4.2.28 K transcriptional
MHKHGFKK_00681 6.5e-93 S GDYXXLXY protein
MHKHGFKK_00682 2.5e-195 S Predicted membrane protein (DUF2157)
MHKHGFKK_00684 2.3e-31 gerE K Transcriptional regulator
MHKHGFKK_00685 6.7e-89 ysmA S thioesterase
MHKHGFKK_00686 1.3e-150 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MHKHGFKK_00687 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MHKHGFKK_00688 2.5e-104 sdhC C succinate dehydrogenase
MHKHGFKK_00689 1.7e-81 yslB S Protein of unknown function (DUF2507)
MHKHGFKK_00690 1.6e-222 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MHKHGFKK_00691 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHKHGFKK_00692 6.7e-53 trxA O Belongs to the thioredoxin family
MHKHGFKK_00693 1.1e-173 etfA C Electron transfer flavoprotein
MHKHGFKK_00694 1.6e-127 etfB C Electron transfer flavoprotein
MHKHGFKK_00695 3e-139 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MHKHGFKK_00696 1.6e-103 fadR K Transcriptional regulator
MHKHGFKK_00697 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHKHGFKK_00698 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHKHGFKK_00699 0.0 polX L COG1796 DNA polymerase IV (family X)
MHKHGFKK_00700 1.4e-87 cvpA S membrane protein, required for colicin V production
MHKHGFKK_00701 1.6e-42 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MHKHGFKK_00702 2.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHKHGFKK_00703 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHKHGFKK_00704 3.2e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHKHGFKK_00707 8.1e-137 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHKHGFKK_00708 2.2e-31 sspI S Belongs to the SspI family
MHKHGFKK_00709 7.7e-76
MHKHGFKK_00710 2.7e-47 S Domain of unknown function (DUF5085)
MHKHGFKK_00711 1.8e-14
MHKHGFKK_00712 3.2e-82
MHKHGFKK_00713 3.8e-16
MHKHGFKK_00714 8.4e-16
MHKHGFKK_00715 6.9e-122 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MHKHGFKK_00716 3.7e-18
MHKHGFKK_00718 9.4e-60 K LysR substrate binding domain
MHKHGFKK_00719 6.5e-102 IQ KR domain
MHKHGFKK_00720 6.6e-143 S COG0491 Zn-dependent hydrolases, including glyoxylases
MHKHGFKK_00721 8.2e-55 yjgB S Domain of unknown function (DUF4309)
MHKHGFKK_00722 2.3e-122 M1-1017 S Protein of unknown function (DUF1129)
MHKHGFKK_00723 1.5e-55 K Transcriptional regulator
MHKHGFKK_00724 2.3e-11 S NADPH-dependent FMN reductase
MHKHGFKK_00725 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MHKHGFKK_00726 2.1e-171 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHKHGFKK_00727 8.9e-101 yieF S NAD(P)H-dependent FMN reductase
MHKHGFKK_00728 2e-122 mcpB3 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MHKHGFKK_00729 1.4e-184 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MHKHGFKK_00730 6.1e-93 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHKHGFKK_00731 2.8e-268 M O-Antigen ligase
MHKHGFKK_00732 7.3e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MHKHGFKK_00734 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHKHGFKK_00735 3.4e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MHKHGFKK_00736 4.5e-112 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHKHGFKK_00737 2.3e-224 G Transmembrane secretion effector
MHKHGFKK_00738 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHKHGFKK_00739 4e-153 ytxC S YtxC-like family
MHKHGFKK_00740 9e-178 dnaI L Primosomal protein DnaI
MHKHGFKK_00741 2.8e-260 dnaB L Membrane attachment protein
MHKHGFKK_00742 2.1e-79 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHKHGFKK_00743 4.9e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHKHGFKK_00744 2.3e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHKHGFKK_00745 1.6e-109 ytaF P Probably functions as a manganese efflux pump
MHKHGFKK_00746 2.3e-153 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHKHGFKK_00747 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHKHGFKK_00748 6.8e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MHKHGFKK_00749 4e-245 icd 1.1.1.42 C isocitrate
MHKHGFKK_00750 1.5e-208 citZ 2.3.3.1 C Belongs to the citrate synthase family
MHKHGFKK_00751 1e-73 yeaL S Membrane
MHKHGFKK_00752 1.3e-159 ytvI S sporulation integral membrane protein YtvI
MHKHGFKK_00753 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MHKHGFKK_00754 3e-176 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHKHGFKK_00755 4.2e-178 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MHKHGFKK_00756 9.9e-163 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHKHGFKK_00757 3.6e-227 ytsJ 1.1.1.38 C Malate dehydrogenase
MHKHGFKK_00758 0.0 dnaE 2.7.7.7 L DNA polymerase
MHKHGFKK_00759 1.6e-41 ytrH S Sporulation protein YtrH
MHKHGFKK_00760 4.2e-89 ytrI
MHKHGFKK_00761 6.4e-176 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MHKHGFKK_00762 5.4e-39 ytpI S YtpI-like protein
MHKHGFKK_00763 1.4e-237 ytoI K transcriptional regulator containing CBS domains
MHKHGFKK_00764 1.5e-129 ytkL S Belongs to the UPF0173 family
MHKHGFKK_00765 1.5e-205 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MHKHGFKK_00766 5.2e-201 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MHKHGFKK_00767 5.6e-80 uspA T Belongs to the universal stress protein A family
MHKHGFKK_00768 5e-156 S EcsC protein family
MHKHGFKK_00769 2.7e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHKHGFKK_00770 2.7e-180 ytxK 2.1.1.72 L DNA methylase
MHKHGFKK_00771 5.8e-91 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MHKHGFKK_00772 2.6e-69 ytfJ S Sporulation protein YtfJ
MHKHGFKK_00773 4.4e-118 ytfI S Protein of unknown function (DUF2953)
MHKHGFKK_00774 4.1e-87 yteJ S RDD family
MHKHGFKK_00775 5.1e-187 sppA OU signal peptide peptidase SppA
MHKHGFKK_00776 3.7e-309 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHKHGFKK_00777 1.4e-27 sspB S spore protein
MHKHGFKK_00778 1.9e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHKHGFKK_00779 2.5e-214 iscS2 2.8.1.7 E Cysteine desulfurase
MHKHGFKK_00780 1e-301 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHKHGFKK_00781 4.6e-117 yttP K Transcriptional regulator
MHKHGFKK_00782 2.7e-85 ytsP 1.8.4.14 T GAF domain-containing protein
MHKHGFKK_00783 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MHKHGFKK_00784 1.9e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHKHGFKK_00785 6.8e-184 putA E Proline dehydrogenase
MHKHGFKK_00786 9.9e-299 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHKHGFKK_00787 1.6e-255 prdR KT Transcriptional regulator
MHKHGFKK_00788 2.5e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHKHGFKK_00789 3.3e-152 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MHKHGFKK_00790 1.3e-50 L Transposase
MHKHGFKK_00791 3.8e-75 zur P Belongs to the Fur family
MHKHGFKK_00792 1.8e-140 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MHKHGFKK_00793 2.9e-142 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MHKHGFKK_00794 1.3e-19 yqfT S Protein of unknown function (DUF2624)
MHKHGFKK_00795 4.9e-124 usp CBM50 M protein conserved in bacteria
MHKHGFKK_00796 6.6e-170 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MHKHGFKK_00797 2.7e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHKHGFKK_00800 5.8e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MHKHGFKK_00801 1.6e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHKHGFKK_00802 1.2e-112 trmK 2.1.1.217 S SAM-dependent methyltransferase
MHKHGFKK_00803 2.2e-63 cccA C Cytochrome C oxidase, cbb3-type, subunit III
MHKHGFKK_00804 2.4e-43 L PFAM Transposase, IS4-like
MHKHGFKK_00805 2.2e-103 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MHKHGFKK_00806 4.9e-36 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MHKHGFKK_00807 4.8e-17 ybzH K ArsR family transcriptional regulator
MHKHGFKK_00808 1.7e-149 ybcL EGP Major facilitator Superfamily
MHKHGFKK_00809 4.6e-45 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MHKHGFKK_00810 1.3e-260 proP EGP Transporter
MHKHGFKK_00811 8e-42
MHKHGFKK_00813 4.9e-142 tesE Q COG3971 2-keto-4-pentenoate hydratase
MHKHGFKK_00814 7.8e-76 nsrR K Transcriptional regulator
MHKHGFKK_00815 3.7e-232 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MHKHGFKK_00816 1.6e-124 S membrane transporter protein
MHKHGFKK_00817 4e-75 dps P Ferritin-like domain
MHKHGFKK_00818 1.5e-183 mocA S Oxidoreductase
MHKHGFKK_00819 9.8e-205 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MHKHGFKK_00820 3.5e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MHKHGFKK_00821 3.8e-84
MHKHGFKK_00822 8e-143 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MHKHGFKK_00823 2.1e-28 sspD S small acid-soluble spore protein
MHKHGFKK_00824 7.3e-19 S Stage 0 Sporulation Regulatory protein
MHKHGFKK_00826 6.3e-290 kinE 2.7.13.3 T Histidine kinase
MHKHGFKK_00827 6.6e-81 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHKHGFKK_00828 1.4e-69 XK27_09985 S Protein of unknown function (DUF1232)
MHKHGFKK_00830 0.0 clpE O Belongs to the ClpA ClpB family
MHKHGFKK_00831 4.3e-181 ykvI S membrane
MHKHGFKK_00832 2.7e-106 S Abortive infection protein
MHKHGFKK_00833 2.5e-26 ykvS S protein conserved in bacteria
MHKHGFKK_00834 7e-28
MHKHGFKK_00835 3.2e-40 ptsH G phosphocarrier protein HPr
MHKHGFKK_00836 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHKHGFKK_00837 4.7e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKHGFKK_00838 1.2e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MHKHGFKK_00839 1.2e-213 patA 2.6.1.1 E Aminotransferase
MHKHGFKK_00840 1.6e-163 cheV 2.7.13.3 T Chemotaxis protein CheV
MHKHGFKK_00841 1.2e-85 ykyB S YkyB-like protein
MHKHGFKK_00842 0.0 ydgH S drug exporters of the RND superfamily
MHKHGFKK_00843 0.0 T Diguanylate cyclase
MHKHGFKK_00844 2e-32
MHKHGFKK_00845 2.1e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKHGFKK_00846 9.6e-169 3.5.1.4 C Acetamidase
MHKHGFKK_00847 5.8e-39 ykuJ S protein conserved in bacteria
MHKHGFKK_00848 6.5e-78 ykuL S CBS domain
MHKHGFKK_00849 4.1e-158 ccpC K Transcriptional regulator
MHKHGFKK_00850 4.7e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MHKHGFKK_00851 1.9e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MHKHGFKK_00852 1.8e-18 S YhfH-like protein
MHKHGFKK_00853 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHKHGFKK_00854 6.8e-30 ykzG S Belongs to the UPF0356 family
MHKHGFKK_00855 9.2e-206 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHKHGFKK_00856 1.3e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHKHGFKK_00857 6.8e-232 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHKHGFKK_00858 9.7e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHKHGFKK_00859 9.2e-34
MHKHGFKK_00861 2.4e-278 speA 4.1.1.19 E Arginine
MHKHGFKK_00863 7.8e-48 yktA S Belongs to the UPF0223 family
MHKHGFKK_00864 6.2e-119 yktB S Belongs to the UPF0637 family
MHKHGFKK_00865 3.1e-24
MHKHGFKK_00866 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
MHKHGFKK_00867 6e-25 S Family of unknown function (DUF5325)
MHKHGFKK_00868 0.0 typA T GTP-binding protein TypA
MHKHGFKK_00869 1.2e-52 ylaH S YlaH-like protein
MHKHGFKK_00870 5.6e-250 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MHKHGFKK_00871 2.2e-87 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MHKHGFKK_00872 1.5e-43 ylaN S Belongs to the UPF0358 family
MHKHGFKK_00873 3e-218 ftsW D Belongs to the SEDS family
MHKHGFKK_00874 3.6e-174 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MHKHGFKK_00875 4.5e-166 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHKHGFKK_00876 5.8e-205 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MHKHGFKK_00877 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHKHGFKK_00878 1.2e-114 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MHKHGFKK_00879 1.4e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MHKHGFKK_00880 3e-176 ctaG S cytochrome c oxidase
MHKHGFKK_00881 7.4e-64 ylbA S YugN-like family
MHKHGFKK_00882 1e-179 ylbC S protein with SCP PR1 domains
MHKHGFKK_00883 4.5e-85 yiiD Q protein, possibly involved in aromatic compounds catabolism
MHKHGFKK_00884 1.7e-69 ylbD S Putative coat protein
MHKHGFKK_00885 1.4e-37 ylbE S YlbE-like protein
MHKHGFKK_00886 8.6e-63
MHKHGFKK_00888 2.5e-15
MHKHGFKK_00889 1.3e-73 ylbF S Belongs to the UPF0342 family
MHKHGFKK_00890 5.3e-46 ylbG S UPF0298 protein
MHKHGFKK_00891 2e-67 S Methylthioribose kinase
MHKHGFKK_00892 2e-106 rsmD 2.1.1.171 L Methyltransferase
MHKHGFKK_00893 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHKHGFKK_00894 5.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
MHKHGFKK_00895 2.4e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
MHKHGFKK_00896 7.4e-189 ylbL T Belongs to the peptidase S16 family
MHKHGFKK_00897 2.6e-247 ylbM S Belongs to the UPF0348 family
MHKHGFKK_00898 7.7e-97 yceD S metal-binding, possibly nucleic acid-binding protein
MHKHGFKK_00899 1e-26 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MHKHGFKK_00900 1.8e-84 rsfA S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MHKHGFKK_00901 8.1e-93 ylbP K n-acetyltransferase
MHKHGFKK_00902 2.4e-161 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHKHGFKK_00903 0.0 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MHKHGFKK_00904 2e-79 mraZ K Belongs to the MraZ family
MHKHGFKK_00905 2.3e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHKHGFKK_00906 2.5e-51 ftsL D Essential cell division protein
MHKHGFKK_00907 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MHKHGFKK_00908 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MHKHGFKK_00909 3.1e-278 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHKHGFKK_00910 1.7e-78 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MHKHGFKK_00911 4.9e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHKHGFKK_00912 2.5e-258 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHKHGFKK_00913 5.9e-189 spoVE D Belongs to the SEDS family
MHKHGFKK_00914 3.5e-205 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHKHGFKK_00915 2.4e-120 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHKHGFKK_00916 1.1e-221 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHKHGFKK_00917 1.2e-189 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHKHGFKK_00918 4.1e-167 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MHKHGFKK_00919 4.5e-113 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHKHGFKK_00920 1.5e-138 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHKHGFKK_00921 1.9e-43 ylmC S sporulation protein
MHKHGFKK_00922 1.3e-72 yocH CBM50 M 3D domain
MHKHGFKK_00923 1.9e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MHKHGFKK_00924 2.9e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MHKHGFKK_00925 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHKHGFKK_00926 2.5e-40 yggT S membrane
MHKHGFKK_00927 3.7e-145 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MHKHGFKK_00928 9.6e-65 divIVA D Cell division initiation protein
MHKHGFKK_00929 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHKHGFKK_00931 2e-80 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHKHGFKK_00932 6.9e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MHKHGFKK_00933 4.5e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHKHGFKK_00934 6.8e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MHKHGFKK_00935 4e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHKHGFKK_00936 0.0 carB 6.3.5.5 F Belongs to the CarB family
MHKHGFKK_00937 4.4e-146 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MHKHGFKK_00938 1.6e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHKHGFKK_00939 4.9e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHKHGFKK_00940 3.1e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHKHGFKK_00941 2.7e-222 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHKHGFKK_00942 0.0 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MHKHGFKK_00943 2.5e-155 glcT K antiterminator
MHKHGFKK_00944 4.7e-233 pbuG S permease
MHKHGFKK_00946 0.0 ywjA V ABC transporter
MHKHGFKK_00947 5e-213 ynfM EGP Major facilitator Superfamily
MHKHGFKK_00948 5.6e-118 yfiK K Regulator
MHKHGFKK_00949 5.4e-198 T Histidine kinase
MHKHGFKK_00950 1.2e-169 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
MHKHGFKK_00951 1.9e-198 yfiM V ABC-2 type transporter
MHKHGFKK_00952 1.2e-205 yfiN V COG0842 ABC-type multidrug transport system, permease component
MHKHGFKK_00953 6.8e-225 1.13.11.4 Q Cupin domain
MHKHGFKK_00954 6.2e-85 S DinB superfamily
MHKHGFKK_00955 7.8e-174 3.7.1.5 Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MHKHGFKK_00956 7.3e-141 K helix_turn_helix isocitrate lyase regulation
MHKHGFKK_00957 2e-56
MHKHGFKK_00958 8.7e-157 1.14.13.127 CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MHKHGFKK_00959 2e-73 ysmA 3.1.2.23 S Thioesterase-like superfamily
MHKHGFKK_00960 1.5e-214 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHKHGFKK_00961 2.1e-67 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHKHGFKK_00962 1e-218 bktB 2.3.1.16, 2.3.1.9 I Belongs to the thiolase family
MHKHGFKK_00963 5.6e-141 4.2.1.17 I Enoyl-CoA hydratase/isomerase
MHKHGFKK_00964 4e-156 hbd 1.1.1.157 I Dehydrogenase
MHKHGFKK_00965 4.3e-175 cyaD 2.7.11.1, 3.1.4.52, 4.6.1.1 QT Domain present in phytochromes and cGMP-specific phosphodiesterases.
MHKHGFKK_00966 1e-214 benK EGP Major facilitator Superfamily
MHKHGFKK_00967 8.6e-142 K helix_turn_helix isocitrate lyase regulation
MHKHGFKK_00968 9.5e-163 3.7.1.20 Q Fumarylacetoacetate (FAA) hydrolase family
MHKHGFKK_00969 8.7e-138 1.13.11.4 Q AraC-like ligand binding domain
MHKHGFKK_00970 9.1e-44 1.13.11.4 Q AraC-like ligand binding domain
MHKHGFKK_00971 9.9e-256 ybhI P Sodium:sulfate symporter transmembrane region
MHKHGFKK_00972 8.4e-49 L deoxyribonuclease I activity
MHKHGFKK_00973 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
MHKHGFKK_00976 1.9e-57
MHKHGFKK_00977 1.8e-248 L PFAM Transposase, IS4-like
MHKHGFKK_00978 2.4e-267 L Transposase
MHKHGFKK_00979 5.3e-43
MHKHGFKK_00980 0.0 yeeA V Type II restriction enzyme, methylase subunits
MHKHGFKK_00981 0.0 yeeB KL DEAD-like helicases superfamily
MHKHGFKK_00982 6.9e-172 pstS P T5orf172
MHKHGFKK_00983 3.3e-161 S Acetyl xylan esterase (AXE1)
MHKHGFKK_00984 2.3e-127 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MHKHGFKK_00985 1.7e-85 thiW S Thiamine-precursor transporter protein (ThiW)
MHKHGFKK_00986 9.8e-241 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MHKHGFKK_00987 2.4e-262 pucI FH Permease for cytosine/purines, uracil, thiamine, allantoin
MHKHGFKK_00988 2.1e-79 yjhE S Phage tail protein
MHKHGFKK_00989 2.3e-141 2.7.1.202 GKT transcriptional antiterminator
MHKHGFKK_00990 6e-35 ulaB 2.7.1.194 G COG3414 Phosphotransferase system, galactitol-specific IIB component
MHKHGFKK_00991 2.8e-196 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MHKHGFKK_00992 0.0 L Domain of unknown function (DUF4277)
MHKHGFKK_00993 4.5e-49 yjdA S LXG domain of WXG superfamily
MHKHGFKK_00994 1.4e-49
MHKHGFKK_00995 1.5e-155 yjdA S LXG domain of WXG superfamily
MHKHGFKK_00996 1.9e-97
MHKHGFKK_00997 9e-75
MHKHGFKK_00998 1e-81 S Domain of unknown function (DUF5085)
MHKHGFKK_01001 1e-190 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHKHGFKK_01002 2e-29 yetF3 K membrane
MHKHGFKK_01003 7.2e-23 yetF3 K membrane
MHKHGFKK_01006 1.6e-08
MHKHGFKK_01010 8.7e-08
MHKHGFKK_01011 1.7e-07
MHKHGFKK_01019 3.3e-261 yihP G MFS/sugar transport protein
MHKHGFKK_01020 1.8e-79 L DDE superfamily endonuclease
MHKHGFKK_01021 4.7e-16 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHKHGFKK_01022 3.6e-115 sodA 1.15.1.1 P Iron/manganese superoxide dismutases, alpha-hairpin domain
MHKHGFKK_01023 6.1e-180 C 4Fe-4S single cluster domain
MHKHGFKK_01024 1.2e-119 nagZ 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MHKHGFKK_01025 8.3e-87 tcaA S response to antibiotic
MHKHGFKK_01026 1.2e-24 S Double zinc ribbon
MHKHGFKK_01027 1.6e-46
MHKHGFKK_01030 2.9e-33 glvR K Helix-turn-helix domain, rpiR family
MHKHGFKK_01031 4.1e-199 glvC 2.7.1.199, 2.7.1.208 G pts system
MHKHGFKK_01032 6e-191 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
MHKHGFKK_01033 1.6e-108 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 CBM50 M Glycosyl hydrolases family 25
MHKHGFKK_01037 5.3e-137 L Reverse transcriptase (RNA-dependent DNA polymerase)
MHKHGFKK_01038 5.5e-37 S 23S rRNA-intervening sequence protein
MHKHGFKK_01039 1.7e-116 S Sulfatase-modifying factor enzyme 1
MHKHGFKK_01040 6.5e-37
MHKHGFKK_01041 8.9e-41
MHKHGFKK_01042 5.8e-22
MHKHGFKK_01043 2.7e-67
MHKHGFKK_01044 1e-138 Z012_12235 S homolog of phage Mu protein gp47
MHKHGFKK_01045 7.6e-16 S Protein of unknown function (DUF2634)
MHKHGFKK_01046 1.2e-21
MHKHGFKK_01047 2.3e-76
MHKHGFKK_01048 3.1e-33
MHKHGFKK_01049 5.6e-34 S HNH endonuclease
MHKHGFKK_01050 2.4e-29 3.5.1.28 M LysM domain
MHKHGFKK_01051 5.1e-98 D phage tail tape measure protein
MHKHGFKK_01052 2e-23
MHKHGFKK_01053 6.4e-24
MHKHGFKK_01054 1.4e-78 Z012_02110 S Protein of unknown function (DUF3383)
MHKHGFKK_01055 1.1e-22
MHKHGFKK_01056 5.3e-14
MHKHGFKK_01057 9.4e-67
MHKHGFKK_01058 2e-18 S Protein of unknown function (DUF4054)
MHKHGFKK_01059 4.8e-20
MHKHGFKK_01060 1.8e-82 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
MHKHGFKK_01061 7.8e-29
MHKHGFKK_01062 9e-97 S Uncharacterized protein conserved in bacteria (DUF2213)
MHKHGFKK_01063 2.6e-58 S Phage Mu protein F like protein
MHKHGFKK_01064 2.8e-156 S Protein of unknown function (DUF1073)
MHKHGFKK_01065 3.5e-189 S Terminase-like family
MHKHGFKK_01066 4.7e-50 L transposase activity
MHKHGFKK_01068 6e-45 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MHKHGFKK_01070 5.5e-99 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
MHKHGFKK_01073 4e-142 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MHKHGFKK_01074 2.9e-16
MHKHGFKK_01075 6.6e-48 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHKHGFKK_01076 9e-55 L Replication initiation and membrane attachment
MHKHGFKK_01077 1.1e-98 S Metallo-beta-lactamase superfamily
MHKHGFKK_01078 6.1e-81 bet L RecT family
MHKHGFKK_01079 1.3e-215 D Psort location Cytoplasmic, score
MHKHGFKK_01084 1.5e-28
MHKHGFKK_01085 4.3e-33
MHKHGFKK_01086 4e-106 K ORF6C domain
MHKHGFKK_01087 1.3e-10 yqaF K Helix-turn-helix XRE-family like proteins
MHKHGFKK_01088 3.1e-35 K transcriptional
MHKHGFKK_01089 2.8e-30 E Pfam:DUF955
MHKHGFKK_01090 5.2e-07
MHKHGFKK_01092 3.1e-27 yhjA S Excalibur calcium-binding domain
MHKHGFKK_01094 3.6e-96 L Arm DNA-binding domain
MHKHGFKK_01095 1.2e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHKHGFKK_01096 4.3e-267 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHKHGFKK_01097 4.2e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MHKHGFKK_01098 7.6e-150 Q N-acetyltransferase
MHKHGFKK_01102 3.9e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHKHGFKK_01103 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHKHGFKK_01104 1.5e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHKHGFKK_01105 2.3e-245 aceA 4.1.3.1 C Isocitrate lyase
MHKHGFKK_01106 0.0 aceB 2.3.3.9 C Belongs to the malate synthase family
MHKHGFKK_01107 2e-219 camS S COG4851 Protein involved in sex pheromone biosynthesis
MHKHGFKK_01108 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHKHGFKK_01109 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MHKHGFKK_01110 1.4e-130 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MHKHGFKK_01111 1.2e-52 yerC S protein conserved in bacteria
MHKHGFKK_01112 3.8e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
MHKHGFKK_01113 0.0 yerA 3.5.4.2 F adenine deaminase
MHKHGFKK_01114 4.2e-36 S Protein of unknown function (DUF2892)
MHKHGFKK_01115 1.1e-226 purD 6.3.4.13 F Belongs to the GARS family
MHKHGFKK_01116 3e-284 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MHKHGFKK_01117 1.1e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MHKHGFKK_01118 4.8e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MHKHGFKK_01119 4.2e-272 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHKHGFKK_01120 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHKHGFKK_01121 3.8e-125 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHKHGFKK_01122 7.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHKHGFKK_01123 3.9e-125 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MHKHGFKK_01124 4.3e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHKHGFKK_01125 1.9e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHKHGFKK_01126 2.9e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHKHGFKK_01127 5.4e-30 yebG S NETI protein
MHKHGFKK_01128 3.1e-90 yebE S UPF0316 protein
MHKHGFKK_01129 4.8e-117 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MHKHGFKK_01133 1e-259 L Mu transposase, C-terminal
MHKHGFKK_01134 2.3e-150 U AAA domain
MHKHGFKK_01135 3.8e-162 ygxA S Nucleotidyltransferase-like
MHKHGFKK_01136 5e-57 ygzB S UPF0295 protein
MHKHGFKK_01137 1.3e-139 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
MHKHGFKK_01138 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MHKHGFKK_01139 3.1e-164 alsR K LysR substrate binding domain
MHKHGFKK_01140 9.8e-82 perR P Belongs to the Fur family
MHKHGFKK_01141 8.9e-101 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
MHKHGFKK_01142 3.4e-65 P Ion transport
MHKHGFKK_01143 1.4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MHKHGFKK_01144 9e-168 ssuA P ABC transporter substrate-binding protein
MHKHGFKK_01145 2.8e-140 P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHKHGFKK_01146 3.8e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MHKHGFKK_01147 2.6e-112 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHKHGFKK_01148 5.4e-226 yitG EGP Major facilitator Superfamily
MHKHGFKK_01149 1.4e-60
MHKHGFKK_01150 4.9e-39 yqhV S Protein of unknown function (DUF2619)
MHKHGFKK_01151 1.1e-187 ygaE S Membrane
MHKHGFKK_01152 2.9e-154 K transcriptional
MHKHGFKK_01153 1.9e-243 sacX 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MHKHGFKK_01154 2.1e-152 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHKHGFKK_01155 5.2e-214 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MHKHGFKK_01156 4.2e-59 ygaD V ABC transporter
MHKHGFKK_01157 1e-230 ygaD V ABC transporter
MHKHGFKK_01158 1.3e-104 ygaC J Belongs to the UPF0374 family
MHKHGFKK_01159 2.7e-36 ygaB S YgaB-like protein
MHKHGFKK_01160 3.3e-09 sspE S Small, acid-soluble spore protein, gamma-type
MHKHGFKK_01161 5.9e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKHGFKK_01162 5.4e-164 gltC K Transcriptional regulator
MHKHGFKK_01163 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MHKHGFKK_01164 5.8e-285 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MHKHGFKK_01165 4.7e-51 S YfzA-like protein
MHKHGFKK_01166 3.5e-101 S ABC-2 family transporter protein
MHKHGFKK_01167 1.5e-158 V ABC transporter
MHKHGFKK_01168 3.1e-22 sspK S reproduction
MHKHGFKK_01169 1.7e-187 yfhP S membrane-bound metal-dependent
MHKHGFKK_01170 1.3e-215 mutY L A G-specific
MHKHGFKK_01171 1e-259 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHKHGFKK_01172 2.8e-252 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
MHKHGFKK_01173 1e-271 EGP Major facilitator Superfamily
MHKHGFKK_01174 9e-113 K Bacterial regulatory proteins, tetR family
MHKHGFKK_01175 1.5e-84 K Winged helix DNA-binding domain
MHKHGFKK_01176 0.0 ydgH S drug exporters of the RND superfamily
MHKHGFKK_01177 1.1e-89 tasA S Cell division protein FtsN
MHKHGFKK_01178 9.4e-48 S Camelysin metallo-endopeptidase
MHKHGFKK_01180 1.6e-61 sipW 3.4.21.89 U Signal peptidase
MHKHGFKK_01181 4.4e-52 S cell adhesion involved in biofilm formation
MHKHGFKK_01182 1.3e-96 XK27_04080 H RibD C-terminal domain
MHKHGFKK_01184 7.4e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
MHKHGFKK_01185 2.9e-54 S DsrE/DsrF-like family
MHKHGFKK_01186 8.2e-76
MHKHGFKK_01187 3.5e-185 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHKHGFKK_01189 3.5e-177 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHKHGFKK_01190 5.8e-275 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
MHKHGFKK_01191 2.8e-82 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MHKHGFKK_01192 1.3e-265 treP 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MHKHGFKK_01193 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MHKHGFKK_01194 2.2e-131 treR K transcriptional
MHKHGFKK_01195 1.3e-230 EG COG2610 H gluconate symporter and related permeases
MHKHGFKK_01197 1.1e-308 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MHKHGFKK_01198 2.2e-125 gntR K transcriptional
MHKHGFKK_01199 6e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MHKHGFKK_01200 1.7e-81 fld C Flavodoxin
MHKHGFKK_01201 1.7e-204 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHKHGFKK_01202 3.3e-138 4.1.99.16, 4.2.3.22, 4.2.3.75 T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MHKHGFKK_01203 0.0 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MHKHGFKK_01204 2.8e-29 P Heavy-metal-associated domain
MHKHGFKK_01206 0.0 nrdA 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHKHGFKK_01207 2.3e-89 fld C Flavodoxin
MHKHGFKK_01208 4e-195 nrdB 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHKHGFKK_01209 8.9e-110 plsY 2.3.1.15 I Belongs to the PlsY family
MHKHGFKK_01210 4.8e-207 crtQ M Glycosyl transferase family 21
MHKHGFKK_01211 1.6e-150 S transposase or invertase
MHKHGFKK_01212 6.9e-18 S transposase or invertase
MHKHGFKK_01213 3.2e-16 S transposase or invertase
MHKHGFKK_01214 6.1e-93 Q Thioesterase superfamily
MHKHGFKK_01215 2.8e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHKHGFKK_01216 1e-48 sugE P Multidrug resistance protein
MHKHGFKK_01217 6.6e-54 ykkC P Multidrug resistance protein
MHKHGFKK_01218 2e-138 yfcA S membrane transporter protein
MHKHGFKK_01219 1.5e-181 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKHGFKK_01220 7.4e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKHGFKK_01221 2.6e-172 fhuD P Periplasmic binding protein
MHKHGFKK_01222 1.6e-151 fhuC 3.6.3.34 HP ABC transporter
MHKHGFKK_01223 7e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MHKHGFKK_01224 2.8e-114
MHKHGFKK_01226 3e-105
MHKHGFKK_01227 2e-106
MHKHGFKK_01228 3.8e-128 yeeN K transcriptional regulatory protein
MHKHGFKK_01229 1.3e-190 T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)
MHKHGFKK_01230 8.9e-242 MA20_26760 1.3.8.7 I COG1960 Acyl-CoA dehydrogenases
MHKHGFKK_01231 5.7e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKHGFKK_01232 2.8e-175 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHKHGFKK_01233 1.5e-74 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHKHGFKK_01234 6.7e-96 K Transcriptional regulator
MHKHGFKK_01235 5.6e-68 S Thioesterase-like superfamily
MHKHGFKK_01236 3.9e-198 S Phosphotransferase enzyme family
MHKHGFKK_01237 5.9e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHKHGFKK_01238 1.5e-280 yobO M Pectate lyase superfamily protein
MHKHGFKK_01239 1.3e-08
MHKHGFKK_01240 3.7e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MHKHGFKK_01241 1.2e-140 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MHKHGFKK_01242 1e-131 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MHKHGFKK_01243 9.1e-110 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MHKHGFKK_01244 9.8e-97 ywhH S Aminoacyl-tRNA editing domain
MHKHGFKK_01245 1.1e-203 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
MHKHGFKK_01246 4.9e-309 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHKHGFKK_01248 5.8e-169 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHKHGFKK_01249 5.8e-166 S Nuclease-related domain
MHKHGFKK_01250 8.4e-45
MHKHGFKK_01251 4.5e-26
MHKHGFKK_01252 2.3e-165 czcD P COG1230 Co Zn Cd efflux system component
MHKHGFKK_01253 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHKHGFKK_01254 2.2e-114 M Glycosyltransferase like family 2
MHKHGFKK_01255 6.2e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases C terminal
MHKHGFKK_01256 6.9e-181 mvaD 4.1.1.33 I GHMP kinases N terminal domain
MHKHGFKK_01257 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases C terminal
MHKHGFKK_01258 2.5e-115 yhfK GM NmrA-like family
MHKHGFKK_01259 9.3e-103 K PTS system fructose IIA component
MHKHGFKK_01260 1.4e-286 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MHKHGFKK_01261 3.8e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHKHGFKK_01262 9.8e-55 yaaQ S protein conserved in bacteria
MHKHGFKK_01263 1.8e-72 yaaR S protein conserved in bacteria
MHKHGFKK_01264 4.3e-186 holB 2.7.7.7 L DNA polymerase III
MHKHGFKK_01265 1.7e-148 yaaT S stage 0 sporulation protein
MHKHGFKK_01266 4.5e-67 yabA L Involved in initiation control of chromosome replication
MHKHGFKK_01267 2.2e-139 yabB 2.1.1.223 S Conserved hypothetical protein 95
MHKHGFKK_01268 1.6e-48 yazA L endonuclease containing a URI domain
MHKHGFKK_01269 5.3e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHKHGFKK_01270 2.1e-53 abrB K COG2002 Regulators of stationary sporulation gene expression
MHKHGFKK_01271 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHKHGFKK_01272 1e-147 tatD L hydrolase, TatD
MHKHGFKK_01273 8.5e-105 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHKHGFKK_01274 2.3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHKHGFKK_01275 8.7e-167 yabG S peptidase
MHKHGFKK_01276 2.4e-37 veg S protein conserved in bacteria
MHKHGFKK_01277 2.2e-34 sspF S DNA topological change
MHKHGFKK_01278 3.2e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHKHGFKK_01279 2.9e-154 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MHKHGFKK_01280 3.2e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MHKHGFKK_01281 3.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MHKHGFKK_01283 2.9e-224 S Psort location CytoplasmicMembrane, score
MHKHGFKK_01284 2.1e-39 V Abc transporter
MHKHGFKK_01285 1e-81
MHKHGFKK_01286 2.3e-246 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHKHGFKK_01287 3.6e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHKHGFKK_01288 2.4e-110 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MHKHGFKK_01289 1.6e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHKHGFKK_01290 1.7e-37 yabK S Peptide ABC transporter permease
MHKHGFKK_01291 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHKHGFKK_01292 6.2e-91 spoVT K stage V sporulation protein
MHKHGFKK_01293 7.2e-292 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHKHGFKK_01294 1.2e-197 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MHKHGFKK_01295 1.1e-41 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MHKHGFKK_01296 4.7e-51 yabP S Sporulation protein YabP
MHKHGFKK_01297 3.1e-110 yabQ S spore cortex biosynthesis protein
MHKHGFKK_01298 5.5e-60 divIC D Septum formation initiator
MHKHGFKK_01299 2.8e-54 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MHKHGFKK_01301 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MHKHGFKK_01302 8.7e-120 yabS S protein containing a von Willebrand factor type A (vWA) domain
MHKHGFKK_01303 2e-167 KLT serine threonine protein kinase
MHKHGFKK_01304 1.4e-278 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHKHGFKK_01305 2.9e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MHKHGFKK_01306 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHKHGFKK_01307 3.8e-142 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MHKHGFKK_01308 3e-159 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHKHGFKK_01309 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MHKHGFKK_01310 1.3e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MHKHGFKK_01311 4.2e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHKHGFKK_01312 1.6e-96 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MHKHGFKK_01313 3.5e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MHKHGFKK_01314 2.3e-229 yjjL G Major facilitator superfamily
MHKHGFKK_01315 1.1e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHKHGFKK_01316 0.0 ppdK 2.7.3.13, 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
MHKHGFKK_01317 7.9e-69 E Glyoxalase
MHKHGFKK_01322 7.6e-197 yrpB 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MHKHGFKK_01324 3.6e-102 5.1.3.34 S oxidoreductase activity
MHKHGFKK_01325 9.1e-95 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MHKHGFKK_01327 2.6e-197 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
MHKHGFKK_01328 1.4e-161 2.1.1.144, 2.1.1.197 S Methyltransferase domain
MHKHGFKK_01329 2.1e-08
MHKHGFKK_01332 4.2e-138 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MHKHGFKK_01333 2e-94 yvbK 3.1.3.25 K acetyltransferase
MHKHGFKK_01334 6.1e-93 VPA1573 J acetyltransferase
MHKHGFKK_01335 3.7e-67 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) family
MHKHGFKK_01336 1.4e-116 yneB L resolvase
MHKHGFKK_01337 4.4e-58 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MHKHGFKK_01338 3.1e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHKHGFKK_01339 4.4e-263 glnA 6.3.1.2 E glutamine synthetase
MHKHGFKK_01340 1.5e-65 glnR K transcriptional
MHKHGFKK_01341 0.0 S Dynamin family
MHKHGFKK_01342 2.9e-33
MHKHGFKK_01343 3.9e-140 f42a O prohibitin homologues
MHKHGFKK_01344 2.3e-232 pbuX F xanthine
MHKHGFKK_01345 7.2e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHKHGFKK_01346 1.7e-298 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MHKHGFKK_01347 2.7e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MHKHGFKK_01348 9e-47 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHKHGFKK_01349 1.4e-101 ypsA S Belongs to the UPF0398 family
MHKHGFKK_01350 8.3e-46 cotD S Inner spore coat protein D
MHKHGFKK_01351 1.7e-251 yprB L RNase_H superfamily
MHKHGFKK_01352 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MHKHGFKK_01353 4.2e-77 hspX O Belongs to the small heat shock protein (HSP20) family
MHKHGFKK_01354 2.9e-71 yppG S YppG-like protein
MHKHGFKK_01355 7e-62 yppE S Bacterial domain of unknown function (DUF1798)
MHKHGFKK_01358 5.5e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHKHGFKK_01359 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MHKHGFKK_01360 2.6e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHKHGFKK_01361 2.6e-129 dnaD L DNA replication protein DnaD
MHKHGFKK_01362 3.4e-263 asnS 6.1.1.22 J asparaginyl-tRNA
MHKHGFKK_01363 8.6e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MHKHGFKK_01364 1.7e-78 ypmB S protein conserved in bacteria
MHKHGFKK_01365 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MHKHGFKK_01366 7.9e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MHKHGFKK_01367 2.5e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MHKHGFKK_01368 4.1e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MHKHGFKK_01369 1.4e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHKHGFKK_01370 1.6e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHKHGFKK_01371 8.3e-221 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MHKHGFKK_01372 3.3e-132 bshB1 S proteins, LmbE homologs
MHKHGFKK_01373 1.5e-149 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHKHGFKK_01374 4.4e-58 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MHKHGFKK_01375 1.4e-161 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MHKHGFKK_01376 3.1e-81 queT S QueT transporter
MHKHGFKK_01377 2.4e-103 yugP S Zn-dependent protease
MHKHGFKK_01378 6e-143 ypjB S sporulation protein
MHKHGFKK_01379 3.6e-108 ypjA S membrane
MHKHGFKK_01380 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MHKHGFKK_01381 1.2e-126 petB C COG1290 Cytochrome b subunit of the bc complex
MHKHGFKK_01382 1e-98 qcrA C Menaquinol-cytochrome c reductase
MHKHGFKK_01383 2e-85 ypiF S Protein of unknown function (DUF2487)
MHKHGFKK_01384 1.7e-99 ypiB S Belongs to the UPF0302 family
MHKHGFKK_01385 4.2e-239 S COG0457 FOG TPR repeat
MHKHGFKK_01386 3.1e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MHKHGFKK_01387 1.3e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MHKHGFKK_01388 3.6e-210 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHKHGFKK_01389 2.9e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MHKHGFKK_01390 1.2e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MHKHGFKK_01391 1.2e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MHKHGFKK_01392 4.9e-145 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MHKHGFKK_01393 2.9e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MHKHGFKK_01394 1.5e-175 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MHKHGFKK_01395 7.5e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MHKHGFKK_01396 1.8e-142 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MHKHGFKK_01397 2.8e-32 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MHKHGFKK_01398 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHKHGFKK_01399 4.1e-278 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MHKHGFKK_01400 1.2e-137 yphF
MHKHGFKK_01401 3.3e-08 yphE S Protein of unknown function (DUF2768)
MHKHGFKK_01402 7.8e-191 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MHKHGFKK_01403 4.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MHKHGFKK_01404 1.2e-18 yphA
MHKHGFKK_01405 7.3e-14 S YpzI-like protein
MHKHGFKK_01406 3.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
MHKHGFKK_01407 1.2e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MHKHGFKK_01408 2.5e-118 ypfA M Flagellar protein YcgR
MHKHGFKK_01409 2.9e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MHKHGFKK_01410 3.9e-150 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MHKHGFKK_01411 2e-126 prsW S Involved in the degradation of specific anti-sigma factors
MHKHGFKK_01412 4.3e-191 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MHKHGFKK_01413 1.2e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MHKHGFKK_01414 2.7e-111 mecB NOT Negative regulator of genetic competence (MecA)
MHKHGFKK_01415 2.4e-144 ypbG S Calcineurin-like phosphoesterase superfamily domain
MHKHGFKK_01416 2.8e-32 cotJA S Spore coat associated protein JA (CotJA)
MHKHGFKK_01417 9.5e-45 cotJB S CotJB protein
MHKHGFKK_01418 2.3e-104 cotJC P Spore Coat
MHKHGFKK_01419 2e-79 ypbF S Protein of unknown function (DUF2663)
MHKHGFKK_01421 1.9e-101 ypbD S metal-dependent membrane protease
MHKHGFKK_01422 7.8e-285 recQ 3.6.4.12 L DNA helicase
MHKHGFKK_01423 3.4e-205 ypbB 5.1.3.1 S protein conserved in bacteria
MHKHGFKK_01424 4.7e-41 fer C Ferredoxin
MHKHGFKK_01425 4.3e-98 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHKHGFKK_01426 2.5e-135 M COG0739 Membrane proteins related to metalloendopeptidases
MHKHGFKK_01427 0.0 resE 2.7.13.3 T Histidine kinase
MHKHGFKK_01428 3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKHGFKK_01429 5.4e-228 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MHKHGFKK_01430 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MHKHGFKK_01431 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MHKHGFKK_01432 9.9e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MHKHGFKK_01433 6.4e-88 spmB S Spore maturation protein
MHKHGFKK_01434 5.2e-96 spmA S Spore maturation protein
MHKHGFKK_01435 1e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MHKHGFKK_01436 1.5e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHKHGFKK_01437 1.9e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHKHGFKK_01438 9e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHKHGFKK_01439 1.4e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHKHGFKK_01440 4.9e-271 spoVAF EG Stage V sporulation protein AF
MHKHGFKK_01441 6.6e-107 spoVAEA S Stage V sporulation protein AE
MHKHGFKK_01442 1.3e-67 spoVAB S Stage V sporulation protein AB
MHKHGFKK_01443 1.6e-111 spoVAA S Stage V sporulation protein AA
MHKHGFKK_01444 1.1e-133 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHKHGFKK_01445 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MHKHGFKK_01446 2.5e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MHKHGFKK_01447 3.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MHKHGFKK_01448 2.1e-168 xerD L recombinase XerD
MHKHGFKK_01449 1.7e-34 S Protein of unknown function (DUF4227)
MHKHGFKK_01450 1.6e-85 fur P Belongs to the Fur family
MHKHGFKK_01451 1.1e-105 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MHKHGFKK_01452 4.3e-230 yqxK 3.6.4.12 L DNA helicase
MHKHGFKK_01453 2.6e-100 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MHKHGFKK_01455 2.4e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MHKHGFKK_01458 9.4e-110 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MHKHGFKK_01459 4e-215 yaaN P Belongs to the TelA family
MHKHGFKK_01461 1.2e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MHKHGFKK_01462 1.7e-241 yaaH_2 M Glycoside Hydrolase Family
MHKHGFKK_01463 2.5e-53 S YolD-like protein
MHKHGFKK_01464 2e-241 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHKHGFKK_01465 2e-146 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MHKHGFKK_01466 1.3e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHKHGFKK_01467 2.2e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHKHGFKK_01468 4.2e-294 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHKHGFKK_01469 1.9e-225 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHKHGFKK_01470 1.4e-78 cheW NT COG0835 Chemotaxis signal transduction protein
MHKHGFKK_01471 1.3e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MHKHGFKK_01472 8.7e-95 yqjB S protein conserved in bacteria
MHKHGFKK_01473 9.3e-77 yqiW S Belongs to the UPF0403 family
MHKHGFKK_01474 3.4e-166 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MHKHGFKK_01475 5.4e-218 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHKHGFKK_01476 8.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHKHGFKK_01477 3.8e-187 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHKHGFKK_01478 2.6e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHKHGFKK_01479 1.5e-208 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MHKHGFKK_01480 4.9e-285 bkdR 2.7.13.3 KT Transcriptional regulator
MHKHGFKK_01481 1.7e-35 yqzF S Protein of unknown function (DUF2627)
MHKHGFKK_01482 1.5e-132 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MHKHGFKK_01483 6.2e-140 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MHKHGFKK_01484 3.4e-236 rseP 3.4.21.116 M Stage IV sporulation protein B
MHKHGFKK_01485 3.3e-295 recN L May be involved in recombinational repair of damaged DNA
MHKHGFKK_01486 6e-79 argR K Regulates arginine biosynthesis genes
MHKHGFKK_01487 1.1e-147 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MHKHGFKK_01488 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHKHGFKK_01489 3.3e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MHKHGFKK_01490 3.1e-31 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHKHGFKK_01491 6.5e-238 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHKHGFKK_01492 3.3e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHKHGFKK_01493 9.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHKHGFKK_01494 1.1e-68 yqhY S protein conserved in bacteria
MHKHGFKK_01495 6.2e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MHKHGFKK_01496 1.2e-80 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHKHGFKK_01497 5.5e-79 spoIIIAH S SpoIIIAH-like protein
MHKHGFKK_01498 2.5e-110 spoIIIAG S stage III sporulation protein AG
MHKHGFKK_01499 1.1e-107 spoIIIAF S stage III sporulation protein AF
MHKHGFKK_01500 3.4e-190 spoIIIAE S stage III sporulation protein AE
MHKHGFKK_01501 1.7e-58 spoIIIAD S Stage III sporulation protein AD
MHKHGFKK_01502 1.4e-27 spoIIIAC S stage III sporulation protein AC
MHKHGFKK_01503 1.7e-85 spoIIIAB S Stage III sporulation protein
MHKHGFKK_01504 1e-170 spoIIIAA S stage III sporulation protein AA
MHKHGFKK_01505 1.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHKHGFKK_01506 1.2e-162 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MHKHGFKK_01507 3.2e-80 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MHKHGFKK_01508 5.3e-86 yqhR S Conserved membrane protein YqhR
MHKHGFKK_01509 4e-162 yqhQ S Protein of unknown function (DUF1385)
MHKHGFKK_01510 1.3e-10 yqhP
MHKHGFKK_01511 6.9e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
MHKHGFKK_01512 2.1e-166 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MHKHGFKK_01513 4e-175 paaX K PaaX-like protein
MHKHGFKK_01514 1.5e-217 paaJ 2.3.1.16, 2.3.1.174, 2.3.1.223, 2.3.1.9 I Belongs to the thiolase family
MHKHGFKK_01515 2.7e-152 ditN 1.1.1.157, 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
MHKHGFKK_01516 8.5e-287 aldA 1.2.1.3, 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MHKHGFKK_01517 9.8e-25 paaG 5.3.3.18 I Enoyl-CoA hydratase
MHKHGFKK_01518 7.7e-97 ycgT 1.18.1.2, 1.19.1.1 C reductase
MHKHGFKK_01520 0.0 nrdA 1.17.4.1 F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
MHKHGFKK_01521 1e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MHKHGFKK_01522 7.7e-67 yqhL P COG0607 Rhodanese-related sulfurtransferase
MHKHGFKK_01523 1.6e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHKHGFKK_01524 1.4e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHKHGFKK_01525 1.4e-214 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MHKHGFKK_01526 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHKHGFKK_01527 5.3e-155 yqhG S Bacterial protein YqhG of unknown function
MHKHGFKK_01528 6.7e-10 yqzE S YqzE-like protein
MHKHGFKK_01529 2.6e-100 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MHKHGFKK_01530 6e-61 S ComG operon protein 7
MHKHGFKK_01531 1.3e-82 comGF U COG4940 Competence protein ComGF
MHKHGFKK_01533 7.2e-77 gspH NU COG2165 Type II secretory pathway, pseudopilin PulG
MHKHGFKK_01534 4e-50 comGC U Required for transformation and DNA binding
MHKHGFKK_01535 2.3e-176 comGB NU COG1459 Type II secretory pathway, component PulF
MHKHGFKK_01536 1.6e-210 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MHKHGFKK_01537 3.1e-130 K Helix-turn-helix domain
MHKHGFKK_01538 5.7e-36 yqgY S Protein of unknown function (DUF2626)
MHKHGFKK_01539 2.9e-124 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MHKHGFKK_01540 7.5e-22 yqgW S Protein of unknown function (DUF2759)
MHKHGFKK_01541 8.4e-179 glcK 2.7.1.2 G Glucokinase
MHKHGFKK_01542 4.5e-30 yqgQ S protein conserved in bacteria
MHKHGFKK_01543 1.3e-207 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MHKHGFKK_01545 1.6e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MHKHGFKK_01546 2.9e-52 yqzD
MHKHGFKK_01547 0.0 mrdA 3.4.16.4 M penicillin-binding protein
MHKHGFKK_01548 1.4e-218 yqgE EGP Major facilitator superfamily
MHKHGFKK_01549 4.8e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MHKHGFKK_01550 9.9e-55 fimV NU Tfp pilus assembly protein FimV
MHKHGFKK_01551 7.3e-203 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MHKHGFKK_01552 4.9e-113 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MHKHGFKK_01553 1.8e-223 L Transposase
MHKHGFKK_01554 0.0 L Domain of unknown function (DUF4277)
MHKHGFKK_01555 9.2e-127 yhcG V ABC transporter, ATP-binding protein
MHKHGFKK_01556 2.8e-58 yhcF K Transcriptional regulator
MHKHGFKK_01557 3.7e-94 padR K transcriptional
MHKHGFKK_01558 2.1e-96 padC Q Phenolic acid decarboxylase
MHKHGFKK_01559 2.1e-114 ywnB S NAD(P)H-binding
MHKHGFKK_01560 9.9e-71 ywnA K Transcriptional regulator
MHKHGFKK_01561 3.9e-11
MHKHGFKK_01562 2.7e-156 S Radical SAM superfamily
MHKHGFKK_01563 8.7e-99 yydH O Peptidase M50
MHKHGFKK_01564 1.2e-82 prrC P ABC transporter
MHKHGFKK_01565 6.4e-91 S ABC-2 family transporter protein
MHKHGFKK_01566 5.5e-13
MHKHGFKK_01568 1.3e-23 L Transposase IS66 family
MHKHGFKK_01569 1.1e-31 rcfB K Bacterial regulatory proteins, crp family
MHKHGFKK_01570 3.2e-16 yeeD O Belongs to the sulfur carrier protein TusA family
MHKHGFKK_01571 2e-23 yeeE S Sulphur transport
MHKHGFKK_01572 6.3e-279 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHKHGFKK_01573 2.1e-148 S transposase or invertase
MHKHGFKK_01574 6.9e-36 yeeD O Belongs to the sulfur carrier protein TusA family
MHKHGFKK_01575 6.5e-193 yeeE S Sulphur transport
MHKHGFKK_01576 5.3e-85 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
MHKHGFKK_01577 6.4e-127 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
MHKHGFKK_01578 3.2e-172 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKHGFKK_01579 1.5e-08
MHKHGFKK_01580 6.3e-30 ybxH S Family of unknown function (DUF5370)
MHKHGFKK_01581 3.3e-79 lmrA 3.6.3.44 V ABC transporter transmembrane region
MHKHGFKK_01584 1.6e-08
MHKHGFKK_01585 4e-08
MHKHGFKK_01589 1.1e-34 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHKHGFKK_01590 0.0 comP 2.7.13.3 T Histidine kinase
MHKHGFKK_01592 4e-164 comQ H Belongs to the FPP GGPP synthase family
MHKHGFKK_01593 6.7e-125 ywdH 1.2.1.3, 1.2.1.71 C Belongs to the aldehyde dehydrogenase family
MHKHGFKK_01594 2e-208 acrA1_1 Q Male sterility protein
MHKHGFKK_01595 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MHKHGFKK_01597 1.5e-243 mcpA NT chemotaxis protein
MHKHGFKK_01598 1e-184 serA1 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHKHGFKK_01599 6.8e-220 dhsS 1.12.1.2 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MHKHGFKK_01600 2.5e-300 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHKHGFKK_01601 1.6e-180 S Phosphotransferase system, EIIC
MHKHGFKK_01602 3.4e-216 2.6.1.9 S HAD-hyrolase-like
MHKHGFKK_01603 3.2e-192 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MHKHGFKK_01604 4.5e-111 leuD 4.2.1.33, 4.2.1.35, 4.2.1.36 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHKHGFKK_01605 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHKHGFKK_01606 4.7e-202 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MHKHGFKK_01607 8.6e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MHKHGFKK_01608 1.8e-195 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MHKHGFKK_01609 1.1e-84 ilvN 2.2.1.6 E Acetolactate synthase
MHKHGFKK_01610 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MHKHGFKK_01611 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MHKHGFKK_01612 3.2e-245 braB E Component of the transport system for branched-chain amino acids
MHKHGFKK_01613 4.1e-153 T STAS domain
MHKHGFKK_01614 1.9e-244
MHKHGFKK_01615 1.1e-217 O Peptidase S53
MHKHGFKK_01616 5.2e-36 S Transcriptional Coactivator p15 (PC4)
MHKHGFKK_01618 5.7e-25 sidE D nuclear chromosome segregation
MHKHGFKK_01619 1.3e-37
MHKHGFKK_01620 2.4e-36
MHKHGFKK_01621 6.7e-98
MHKHGFKK_01622 1.1e-151 S transposase or invertase
MHKHGFKK_01624 5e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MHKHGFKK_01625 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MHKHGFKK_01626 7.5e-143 est 3.1.1.1 S Carboxylesterase
MHKHGFKK_01627 2.5e-28 secG U Preprotein translocase subunit SecG
MHKHGFKK_01628 2.9e-129 L DNA synthesis involved in DNA repair
MHKHGFKK_01629 3.9e-137 3.6.4.12 L ATP-dependent DNA helicase activity
MHKHGFKK_01630 1.3e-59 L resolvase
MHKHGFKK_01631 1.5e-88 L RNA-directed DNA polymerase (reverse transcriptase)
MHKHGFKK_01632 1e-223 mvaS 2.3.3.10 I synthase
MHKHGFKK_01633 6.5e-136 tnp L PFAM Transposase, Mutator
MHKHGFKK_01634 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
MHKHGFKK_01635 1.1e-273 lysP E amino acid
MHKHGFKK_01636 5.3e-116 K Transcriptional regulator
MHKHGFKK_01637 3.4e-209 ybhR V COG0842 ABC-type multidrug transport system, permease component
MHKHGFKK_01639 1.6e-129 V COG1131 ABC-type multidrug transport system, ATPase component
MHKHGFKK_01640 8e-70 S Hemerythrin HHE cation binding domain
MHKHGFKK_01641 4.6e-51
MHKHGFKK_01642 1.9e-43
MHKHGFKK_01643 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHKHGFKK_01644 2.5e-307 narH 1.7.5.1 C Nitrate reductase, beta
MHKHGFKK_01645 1.8e-99 narJ C nitrate reductase molybdenum cofactor assembly chaperone
MHKHGFKK_01646 1.6e-126 narI 1.7.5.1 C nitrate reductase, gamma subunit
MHKHGFKK_01647 6.2e-205 narT P COG2223 Nitrate nitrite transporter
MHKHGFKK_01648 1.5e-161 fda 4.1.2.13 G Belongs to the class I fructose-bisphosphate aldolase family
MHKHGFKK_01649 2.3e-200 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
MHKHGFKK_01650 2.8e-22 M COG3209 Rhs family protein
MHKHGFKK_01651 1.4e-97 M SIS domain
MHKHGFKK_01652 6.8e-32 G PTS system fructose IIA component
MHKHGFKK_01653 3.8e-42 S HAD hydrolase, family IA, variant 3
MHKHGFKK_01654 6.1e-146 2.1.1.21 M SIS domain
MHKHGFKK_01655 3.6e-58 G PTS system sorbose subfamily IIB component
MHKHGFKK_01656 1e-100 G PTS system mannose/fructose/sorbose family IID component
MHKHGFKK_01657 1.5e-69 G PTS system sorbose-specific iic component
MHKHGFKK_01658 3.5e-65 K UTRA domain
MHKHGFKK_01659 1.1e-25 frlR K UTRA
MHKHGFKK_01660 3.9e-226 2.3.1.179 IQ Beta-ketoacyl synthase, C-terminal domain
MHKHGFKK_01661 4.6e-31 cspL K Cold shock
MHKHGFKK_01662 4.4e-42 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHKHGFKK_01663 1.8e-179 ydcZ S Putative inner membrane exporter, YdcZ
MHKHGFKK_01664 0.0 nagA 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MHKHGFKK_01665 1.6e-310 ampC V Belongs to the UPF0214 family
MHKHGFKK_01666 9.1e-234 ybbC 3.2.1.52 S protein conserved in bacteria
MHKHGFKK_01667 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHKHGFKK_01668 0.0 yfiB V ABC transporter
MHKHGFKK_01669 2.5e-80 K helix_turn_helix multiple antibiotic resistance protein
MHKHGFKK_01670 5.3e-104 iolR K COG1349 Transcriptional regulators of sugar metabolism
MHKHGFKK_01672 1e-116 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MHKHGFKK_01673 1.9e-153 iolH G Xylose isomerase-like TIM barrel
MHKHGFKK_01674 7.2e-152 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MHKHGFKK_01675 4.7e-202 iolT EGP Major facilitator Superfamily
MHKHGFKK_01676 1.2e-142 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MHKHGFKK_01677 2.9e-114 S Oxidoreductase
MHKHGFKK_01678 9.3e-24 yxlH EGP Major facilitator Superfamily
MHKHGFKK_01679 1.5e-131 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MHKHGFKK_01680 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MHKHGFKK_01681 2e-143 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MHKHGFKK_01682 1.4e-131 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MHKHGFKK_01683 1.7e-247 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHKHGFKK_01684 1.1e-96 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MHKHGFKK_01686 5.1e-103 P Integral membrane protein TerC family
MHKHGFKK_01687 2.2e-141 XK27_04815 S Membrane transport protein
MHKHGFKK_01688 2.7e-304 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MHKHGFKK_01689 7e-23 S Uncharacterized small protein (DUF2292)
MHKHGFKK_01690 4.6e-94 ssuE 1.5.1.38 S FMN reductase
MHKHGFKK_01691 3.3e-138 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
MHKHGFKK_01692 2e-135 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHKHGFKK_01693 9e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MHKHGFKK_01694 6.8e-160 P ABC transporter substrate-binding protein
MHKHGFKK_01695 8.5e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHKHGFKK_01697 5.8e-85 S SMI1-KNR4 cell-wall
MHKHGFKK_01698 5.3e-44 S Protein of unknown function (DUF3969)
MHKHGFKK_01700 5.4e-75 ctsR K Belongs to the CtsR family
MHKHGFKK_01701 6.1e-102 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MHKHGFKK_01702 7.8e-194 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MHKHGFKK_01703 0.0 clpC O Belongs to the ClpA ClpB family
MHKHGFKK_01704 9.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHKHGFKK_01705 4e-198 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MHKHGFKK_01706 1.5e-121 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MHKHGFKK_01707 1.1e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MHKHGFKK_01708 1.8e-281 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHKHGFKK_01709 6.3e-109 cysE 2.3.1.30 E Serine acetyltransferase
MHKHGFKK_01710 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHKHGFKK_01711 7.9e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHKHGFKK_01712 3.3e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHKHGFKK_01713 8.7e-90 yacP S RNA-binding protein containing a PIN domain
MHKHGFKK_01714 2.4e-113 sigH K Belongs to the sigma-70 factor family
MHKHGFKK_01716 1e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHKHGFKK_01717 1.4e-95 nusG K Participates in transcription elongation, termination and antitermination
MHKHGFKK_01718 1.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHKHGFKK_01719 9.5e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHKHGFKK_01721 5.4e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHKHGFKK_01722 1.3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHKHGFKK_01723 8.5e-113 rsmC 2.1.1.172 J Methyltransferase
MHKHGFKK_01724 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHKHGFKK_01725 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHKHGFKK_01726 2.6e-36 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
MHKHGFKK_01727 8.6e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHKHGFKK_01728 9.3e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHKHGFKK_01729 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHKHGFKK_01730 2.7e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHKHGFKK_01731 2.5e-73 3.2.1.20 GH31 S Protein of unknown function (DUF2961)
MHKHGFKK_01732 7.8e-290
MHKHGFKK_01733 3e-218 EGP Major facilitator superfamily
MHKHGFKK_01734 1.1e-262 yheS_2 S ABC transporter
MHKHGFKK_01735 7.9e-47 S Nucleotidyltransferase domain
MHKHGFKK_01736 2.1e-173 2.1.1.21 E Conserved region in glutamate synthase
MHKHGFKK_01737 1.3e-111 mta K TipAS antibiotic-recognition domain
MHKHGFKK_01738 1.1e-242 L COG3547 Transposase and inactivated derivatives
MHKHGFKK_01739 1.3e-44 K transcriptional regulator
MHKHGFKK_01740 2.7e-95 K TipAS antibiotic-recognition domain
MHKHGFKK_01741 5.1e-185 EGP Major facilitator Superfamily
MHKHGFKK_01742 1.5e-70 2.3.1.128 K PFAM GCN5-related N-acetyltransferase
MHKHGFKK_01743 1.3e-70 S Nucleotidyltransferase domain
MHKHGFKK_01744 7.3e-123 vatD S Bacterial transferase hexapeptide (six repeats)
MHKHGFKK_01745 3.6e-165 MA20_01270 K AraC family transcriptional regulator
MHKHGFKK_01746 1.4e-25 S Rifampin ADP-ribosyl transferase
MHKHGFKK_01747 1e-101 S Rifampin ADP-ribosyl transferase
MHKHGFKK_01748 2.2e-10 L PFAM transposase, IS4 family protein
MHKHGFKK_01749 4.6e-18
MHKHGFKK_01750 2e-43 L PFAM Transposase, IS4-like
MHKHGFKK_01751 9.1e-64 L PFAM Transposase, IS4-like
MHKHGFKK_01752 8.5e-75 K transcriptional
MHKHGFKK_01753 5.1e-210 EGP Major facilitator Superfamily
MHKHGFKK_01754 5.9e-180 K Transcriptional regulator
MHKHGFKK_01755 0.0 bga2 3.2.1.23 G beta-galactosidase
MHKHGFKK_01756 1.2e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MHKHGFKK_01757 1.1e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHKHGFKK_01758 3.4e-115 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MHKHGFKK_01759 5.7e-211 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHKHGFKK_01760 4.5e-97 yvbF K Belongs to the GbsR family
MHKHGFKK_01761 1.5e-95 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
MHKHGFKK_01762 2.3e-128 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MHKHGFKK_01763 6.2e-151 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MHKHGFKK_01764 5.7e-61 yojF S Protein of unknown function (DUF1806)
MHKHGFKK_01765 1.6e-128 bshB2 S deacetylase
MHKHGFKK_01766 9.8e-163 ycsE S hydrolases of the HAD superfamily
MHKHGFKK_01767 0.0 recQ 3.6.4.12 L DNA helicase
MHKHGFKK_01768 3.6e-230 phoA 3.1.3.1 P Belongs to the alkaline phosphatase family
MHKHGFKK_01769 2.2e-151 ybbH_2 K Transcriptional regulator
MHKHGFKK_01770 2.7e-160 S Alpha/beta hydrolase of unknown function (DUF915)
MHKHGFKK_01771 1.3e-13
MHKHGFKK_01772 1.5e-75 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHKHGFKK_01774 2.2e-117 ywbG M effector of murein hydrolase
MHKHGFKK_01775 3.7e-58 ywbH S LrgA family
MHKHGFKK_01776 2.3e-181 ywbI K Transcriptional regulator
MHKHGFKK_01777 0.0 asnO 6.3.5.4 E Asparagine synthase
MHKHGFKK_01778 2.4e-144 S Protein of unknown function (DUF1646)
MHKHGFKK_01779 2.7e-71 S Threonine/Serine exporter, ThrE
MHKHGFKK_01780 3.3e-130 thrE S Putative threonine/serine exporter
MHKHGFKK_01781 7.3e-208 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MHKHGFKK_01782 0.0 cstA T Carbon starvation protein
MHKHGFKK_01783 5.1e-125 lytT T COG3279 Response regulator of the LytR AlgR family
MHKHGFKK_01784 0.0 lytS 2.7.13.3 T Histidine kinase
MHKHGFKK_01785 1.7e-140 metQ M Belongs to the nlpA lipoprotein family
MHKHGFKK_01786 4.8e-101 metI P COG2011 ABC-type metal ion transport system, permease component
MHKHGFKK_01787 7.1e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHKHGFKK_01788 6.2e-140 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MHKHGFKK_01789 1.6e-100
MHKHGFKK_01790 6.3e-221 pilM NU Pilus assembly protein
MHKHGFKK_01791 2.8e-241 yisQ V Mate efflux family protein
MHKHGFKK_01792 2.5e-152 M Glycosyl transferase family 8
MHKHGFKK_01793 2.5e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MHKHGFKK_01794 4.5e-272 EGP Major facilitator Superfamily
MHKHGFKK_01795 3.2e-226 uraA F Xanthine uracil
MHKHGFKK_01796 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MHKHGFKK_01797 2.1e-126 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHKHGFKK_01798 3.5e-300 msbA2 3.6.3.44 V ABC transporter
MHKHGFKK_01799 1e-111 yhhQ_2 S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MHKHGFKK_01800 2.2e-98 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MHKHGFKK_01801 0.0 S MMPL domain protein
MHKHGFKK_01802 1.9e-291 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
MHKHGFKK_01803 1.1e-43 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MHKHGFKK_01804 6.6e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHKHGFKK_01805 8.9e-239 LYS1 1.5.1.7 E Saccharopine dehydrogenase
MHKHGFKK_01806 5.3e-225 nspC 4.1.1.96 E Pyridoxal-dependent decarboxylase, C-terminal sheet domain
MHKHGFKK_01807 1.9e-32 S PD-(D/E)XK nuclease family transposase
MHKHGFKK_01808 4.7e-207 S Domain of unknown function (DUF1611_N) Rossmann-like domain
MHKHGFKK_01809 3e-215 5.1.1.12 E Alanine racemase, N-terminal domain
MHKHGFKK_01810 3.1e-137 cjaA ET Belongs to the bacterial solute-binding protein 3 family
MHKHGFKK_01811 6e-129 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
MHKHGFKK_01812 1.4e-103 E amino acid ABC transporter
MHKHGFKK_01813 3.4e-115 papP E amino acid ABC transporter
MHKHGFKK_01814 4.6e-293 mqo 1.1.5.4 S malate quinone oxidoreductase
MHKHGFKK_01815 3.1e-240 kgtP EGP -transporter
MHKHGFKK_01816 4.2e-59 K PadR family transcriptional regulator
MHKHGFKK_01817 1.6e-39 S Protein of unknown function (DUF1048)
MHKHGFKK_01818 5.8e-53 S Protein of unknown function (DUF1048)
MHKHGFKK_01819 8.4e-46 S Protein of unknown function (DUF1048)
MHKHGFKK_01821 6.2e-74 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHKHGFKK_01822 1.8e-181 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHKHGFKK_01823 8.5e-145 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MHKHGFKK_01824 1.7e-142 yycI S protein conserved in bacteria
MHKHGFKK_01825 2.3e-248 yycH S protein conserved in bacteria
MHKHGFKK_01826 0.0 vicK 2.7.13.3 T Histidine kinase
MHKHGFKK_01827 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKHGFKK_01830 1.2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHKHGFKK_01831 3.7e-249 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MHKHGFKK_01832 1.2e-71 rplI J binds to the 23S rRNA
MHKHGFKK_01833 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MHKHGFKK_01834 1.8e-146 yybS S membrane
MHKHGFKK_01835 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHKHGFKK_01836 1.5e-86 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHKHGFKK_01837 5e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
MHKHGFKK_01838 7.4e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MHKHGFKK_01839 6.2e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MHKHGFKK_01840 2.6e-115 ribE 2.5.1.9 H Riboflavin synthase
MHKHGFKK_01841 2.3e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MHKHGFKK_01842 5.9e-205 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHKHGFKK_01843 1.1e-32 yyzM S protein conserved in bacteria
MHKHGFKK_01844 1.1e-161 ykuT M Mechanosensitive ion channel
MHKHGFKK_01845 3.3e-112 yyaC S Sporulation protein YyaC
MHKHGFKK_01846 6.2e-118 ydfK S Protein of unknown function (DUF554)
MHKHGFKK_01847 1.2e-149 spo0J K Belongs to the ParB family
MHKHGFKK_01848 6.9e-136 soj D COG1192 ATPases involved in chromosome partitioning
MHKHGFKK_01849 5.9e-152 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MHKHGFKK_01850 1.8e-133 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MHKHGFKK_01851 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHKHGFKK_01852 5.8e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHKHGFKK_01853 8.2e-111 jag S single-stranded nucleic acid binding R3H
MHKHGFKK_01854 1.4e-128 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHKHGFKK_01855 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MHKHGFKK_01856 1.3e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHKHGFKK_01857 4.7e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHKHGFKK_01858 2e-32 yaaA S S4 domain
MHKHGFKK_01859 1.6e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHKHGFKK_01860 7.3e-11 yaaB S Domain of unknown function (DUF370)
MHKHGFKK_01861 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHKHGFKK_01862 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHKHGFKK_01863 1.5e-197 M1-161 T HD domain
MHKHGFKK_01868 1.3e-07
MHKHGFKK_01869 1.5e-07
MHKHGFKK_01873 1.1e-169 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MHKHGFKK_01875 1.9e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MHKHGFKK_01876 5.8e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MHKHGFKK_01877 9.4e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHKHGFKK_01878 9.3e-223 ybbR S protein conserved in bacteria
MHKHGFKK_01879 4.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHKHGFKK_01880 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHKHGFKK_01882 1.2e-94 M1-431 S Protein of unknown function (DUF1706)
MHKHGFKK_01883 6.8e-144 3.1.2.21 I Acyl-ACP thioesterase
MHKHGFKK_01884 5e-65
MHKHGFKK_01885 1.7e-116 E lactoylglutathione lyase activity
MHKHGFKK_01886 1.6e-233 lmrP E Transmembrane secretion effector
MHKHGFKK_01887 1.1e-74 yycN 2.3.1.128, 2.3.1.57 K FR47-like protein
MHKHGFKK_01888 2.8e-132 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MHKHGFKK_01889 1.9e-127 V CAAX protease self-immunity
MHKHGFKK_01890 1.3e-45 L transposase, IS605 OrfB family
MHKHGFKK_01891 7.7e-112 L transposase, IS605 OrfB family
MHKHGFKK_01892 2.8e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 I Hydroxymethylglutaryl-coenzyme A reductase
MHKHGFKK_01893 2.9e-22
MHKHGFKK_01894 8e-63 L IS66 Orf2 like protein
MHKHGFKK_01895 5.9e-307 L Transposase IS66 family
MHKHGFKK_01897 4.3e-11 L Transposase, IS4 family protein
MHKHGFKK_01898 1.4e-18 ybxH S Family of unknown function (DUF5370)
MHKHGFKK_01899 1.9e-189 P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MHKHGFKK_01900 3.3e-138 fecE 3.6.3.34 HP ABC transporter
MHKHGFKK_01901 9e-174 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKHGFKK_01902 3.1e-93
MHKHGFKK_01904 4.3e-147 emrB P Major facilitator superfamily
MHKHGFKK_01905 2.6e-62 EGP Major facilitator Superfamily
MHKHGFKK_01906 1.4e-27 K Helix-turn-helix domain
MHKHGFKK_01907 4.7e-31
MHKHGFKK_01908 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
MHKHGFKK_01909 4.4e-89 yrhD S Protein of unknown function (DUF1641)
MHKHGFKK_01910 2.1e-193 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MHKHGFKK_01911 2.7e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MHKHGFKK_01912 3e-34 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MHKHGFKK_01913 3.9e-78 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MHKHGFKK_01914 3.4e-88 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MHKHGFKK_01915 3e-237 moeA 2.10.1.1 H molybdopterin
MHKHGFKK_01916 4.7e-120 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MHKHGFKK_01917 3.1e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MHKHGFKK_01918 1.1e-186 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MHKHGFKK_01919 3.1e-130 modC 3.6.3.29 P ATPases associated with a variety of cellular activities
MHKHGFKK_01920 2.5e-101 P COG4149 ABC-type molybdate transport system, permease component
MHKHGFKK_01921 5.4e-128 modA P Molybdenum ABC transporter
MHKHGFKK_01922 1.2e-160 narK P Major Facilitator Superfamily
MHKHGFKK_01923 2e-79 ywiC S YwiC-like protein
MHKHGFKK_01924 3.3e-92 narI 1.7.5.1 C nitrate reductase, gamma subunit
MHKHGFKK_01925 9.6e-47 narJ 1.7.5.1 C Nitrate reductase delta subunit
MHKHGFKK_01926 7e-262 narH 1.7.5.1 C 4Fe-4S dicluster domain
MHKHGFKK_01927 0.0 narG 1.7.5.1 C Molybdopterin oxidoreductase Fe4S4 domain
MHKHGFKK_01928 7.2e-100 fnr K helix_turn_helix, cAMP Regulatory protein
MHKHGFKK_01929 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHKHGFKK_01930 5.2e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MHKHGFKK_01931 3.2e-118 acuB S Acetoin utilization protein AcuB
MHKHGFKK_01932 5.4e-233 acuC BQ histone deacetylase
MHKHGFKK_01933 1.3e-182 ccpA K catabolite control protein A
MHKHGFKK_01934 3.8e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MHKHGFKK_01935 4.2e-33 XK27_07760 S COG4980 Gas vesicle protein
MHKHGFKK_01936 5.6e-52 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHKHGFKK_01937 8.8e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MHKHGFKK_01938 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MHKHGFKK_01939 6.1e-69 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHKHGFKK_01940 2e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHKHGFKK_01941 3.4e-146 ytpQ S Belongs to the UPF0354 family
MHKHGFKK_01942 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MHKHGFKK_01943 8e-205 rsbU 3.1.3.3 T response regulator
MHKHGFKK_01944 7.3e-155 cheR 2.1.1.80 NT chemotaxis
MHKHGFKK_01945 0.0 T PhoQ Sensor
MHKHGFKK_01946 2.2e-192 EGP Transmembrane secretion effector
MHKHGFKK_01948 3.8e-33
MHKHGFKK_01949 4.2e-92 yjjX F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
MHKHGFKK_01950 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MHKHGFKK_01951 3.3e-52 ytzB S small secreted protein
MHKHGFKK_01952 1.1e-169 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MHKHGFKK_01954 1.8e-130 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHKHGFKK_01955 1.7e-57 ytzH S YtzH-like protein
MHKHGFKK_01956 6.2e-156 ytmP 2.7.1.89 M Phosphotransferase
MHKHGFKK_01957 7.5e-148 ytlQ
MHKHGFKK_01958 2e-108 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MHKHGFKK_01960 1.5e-158 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MHKHGFKK_01961 2.5e-272 pepV 3.5.1.18 E Dipeptidase
MHKHGFKK_01962 1.2e-32 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MHKHGFKK_01963 7e-287 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHKHGFKK_01964 4.1e-26 yteV S Sporulation protein Cse60
MHKHGFKK_01965 1.7e-10
MHKHGFKK_01967 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHKHGFKK_01968 4.3e-185 yttB EGP Major facilitator Superfamily
MHKHGFKK_01969 1.6e-42 ytzC S Protein of unknown function (DUF2524)
MHKHGFKK_01970 5.2e-104 ytqB J Putative rRNA methylase
MHKHGFKK_01972 1e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MHKHGFKK_01973 2e-154 ytpA 3.1.1.5 I Alpha beta hydrolase
MHKHGFKK_01974 2.5e-73 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MHKHGFKK_01975 0.0 asnB 6.3.5.4 E Asparagine synthase
MHKHGFKK_01976 5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHKHGFKK_01977 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MHKHGFKK_01978 4.8e-69 3.6.1.13, 3.6.1.55 L NTP pyrophosphohydrolases including oxidative damage repair enzymes
MHKHGFKK_01979 1.1e-197 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MHKHGFKK_01980 2.5e-100 ywqN S NAD(P)H-dependent
MHKHGFKK_01981 8.3e-298 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MHKHGFKK_01983 2.7e-82 2.3.1.57 K Acetyltransferase (GNAT) domain
MHKHGFKK_01984 2.2e-10
MHKHGFKK_01985 1.2e-214 S Psort location CytoplasmicMembrane, score
MHKHGFKK_01986 1.8e-121 yfiR K Bacterial regulatory proteins, tetR family
MHKHGFKK_01987 3.3e-228 yfiS EGP Major facilitator Superfamily
MHKHGFKK_01988 3.4e-135 thiX 2.7.1.50 P binding-protein-dependent transport systems inner membrane component
MHKHGFKK_01989 4.2e-186 nrtA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MHKHGFKK_01991 4.3e-73 S Glyoxalase bleomycin resistance protein dioxygenase
MHKHGFKK_01992 3e-150 yitD 4.4.1.19 S synthase
MHKHGFKK_01993 6.5e-133 comB 3.1.3.71 H Belongs to the ComB family
MHKHGFKK_01994 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MHKHGFKK_01995 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MHKHGFKK_01996 7.4e-109
MHKHGFKK_01997 1.1e-133 mta K transcriptional
MHKHGFKK_01998 1.3e-270 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
MHKHGFKK_01999 8e-177 yjlA EG Putative multidrug resistance efflux transporter
MHKHGFKK_02000 1.3e-187 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHKHGFKK_02001 2.2e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHKHGFKK_02002 2.8e-216 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHKHGFKK_02003 1.1e-259 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHKHGFKK_02004 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MHKHGFKK_02005 1.4e-190 kefA M Mechanosensitive ion channel
MHKHGFKK_02006 3e-192 S COG0491 Zn-dependent hydrolases, including glyoxylases
MHKHGFKK_02007 4.1e-56 I SCP-2 sterol transfer family
MHKHGFKK_02009 9.2e-172 nrdB 1.17.4.1 F Ribonucleotide reductase, small chain
MHKHGFKK_02010 7.5e-17 nrdB 1.17.4.1 F Ribonucleotide reductase, small chain
MHKHGFKK_02011 4.4e-103 S Appr-1'-p processing enzyme
MHKHGFKK_02012 2e-25 sspH S small acid-soluble spore protein
MHKHGFKK_02013 1.1e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MHKHGFKK_02014 3.2e-209 2.3.1.16, 2.3.1.9 I Belongs to the thiolase family
MHKHGFKK_02015 1.1e-289 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHKHGFKK_02016 1.9e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MHKHGFKK_02017 3.9e-150 S Sucrose-6F-phosphate phosphohydrolase
MHKHGFKK_02018 2.7e-97 yozB S membrane
MHKHGFKK_02019 2e-59
MHKHGFKK_02020 1.4e-78 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHKHGFKK_02021 4.9e-179 ldh1 1.1.1.27 C Belongs to the LDH MDH superfamily
MHKHGFKK_02022 9.4e-130 IQ Enoyl-(Acyl carrier protein) reductase
MHKHGFKK_02023 3.6e-216 fsr P COG0477 Permeases of the major facilitator superfamily
MHKHGFKK_02024 2.2e-78 sleB 3.5.1.28 M Cell wall
MHKHGFKK_02025 2e-148 xth 3.1.11.2 L exodeoxyribonuclease III
MHKHGFKK_02026 2.3e-156 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MHKHGFKK_02027 1.3e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MHKHGFKK_02028 3.1e-193 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
MHKHGFKK_02029 6.4e-210 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MHKHGFKK_02030 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MHKHGFKK_02031 3.1e-197 G Glycosyl hydrolases family 15
MHKHGFKK_02032 3e-22 S YpzG-like protein
MHKHGFKK_02033 2.5e-89 Q protein disulfide oxidoreductase activity
MHKHGFKK_02034 1.8e-95 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MHKHGFKK_02035 7.4e-120 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MHKHGFKK_02036 1.5e-228 mntH P H( )-stimulated, divalent metal cation uptake system
MHKHGFKK_02037 9.5e-77 dps P Ferritin-like domain
MHKHGFKK_02038 8.6e-81 V VanZ like family
MHKHGFKK_02039 3.9e-165 yhcI S ABC-2 family transporter protein
MHKHGFKK_02040 8.4e-168 ydbJ V ABC transporter, ATP-binding protein
MHKHGFKK_02041 1.2e-55
MHKHGFKK_02042 1.4e-167 murB 1.3.1.98 M cell wall formation
MHKHGFKK_02043 2.4e-92 S Protein of unknown function (DUF1189)
MHKHGFKK_02044 2.4e-37 S Protein of unknown function (DUF1450)
MHKHGFKK_02045 2.7e-271 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHKHGFKK_02046 2.7e-70 I MaoC like domain
MHKHGFKK_02047 3.5e-79 I N-terminal half of MaoC dehydratase
MHKHGFKK_02048 6.9e-136 IQ Enoyl-(Acyl carrier protein) reductase
MHKHGFKK_02049 1.5e-261 dld 1.1.1.303, 1.1.1.4, 1.1.2.4 C Glycolate oxidase subunit
MHKHGFKK_02051 1.9e-200 selU S tRNA 2-selenouridine synthase
MHKHGFKK_02052 6.9e-195 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
MHKHGFKK_02053 6.5e-136 T Calcineurin-like phosphoesterase superfamily domain
MHKHGFKK_02054 2.9e-193 yraQ S Predicted permease
MHKHGFKK_02055 4.6e-230 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHKHGFKK_02056 5.5e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHKHGFKK_02057 9.2e-72 yjlC S Protein of unknown function (DUF1641)
MHKHGFKK_02058 1.1e-217 yjlD 1.6.99.3 C NADH dehydrogenase
MHKHGFKK_02059 4.4e-230 nrnB S phosphohydrolase (DHH superfamily)
MHKHGFKK_02060 1e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MHKHGFKK_02061 2.7e-130 yvpB NU protein conserved in bacteria
MHKHGFKK_02062 1.1e-50 tnrA K transcriptional
MHKHGFKK_02063 1.4e-109 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHKHGFKK_02064 1.1e-23 S Virus attachment protein p12 family
MHKHGFKK_02065 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MHKHGFKK_02066 1.3e-47 feoA P COG1918 Fe2 transport system protein A
MHKHGFKK_02067 2.5e-225 dapL 2.6.1.83 E Aminotransferase
MHKHGFKK_02068 7.6e-266 argH 4.3.2.1 E argininosuccinate lyase
MHKHGFKK_02069 4.8e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHKHGFKK_02070 1.7e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHKHGFKK_02071 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MHKHGFKK_02072 8.6e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MHKHGFKK_02073 3e-226 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MHKHGFKK_02074 2.1e-140 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MHKHGFKK_02075 2.2e-232 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MHKHGFKK_02076 2e-199 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MHKHGFKK_02078 6.5e-81
MHKHGFKK_02079 5.7e-152 yjqC P Catalase
MHKHGFKK_02080 2.9e-84
MHKHGFKK_02081 2.3e-30 cspD K Cold shock
MHKHGFKK_02083 1.4e-172 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MHKHGFKK_02084 2.5e-283 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MHKHGFKK_02085 1.1e-106 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MHKHGFKK_02086 3.4e-74 yneK S Protein of unknown function (DUF2621)
MHKHGFKK_02087 4.6e-77 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MHKHGFKK_02088 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MHKHGFKK_02089 9.9e-129 ccdA O cytochrome c biogenesis protein
MHKHGFKK_02090 6.8e-28 yneF S UPF0154 protein
MHKHGFKK_02091 4.2e-77 yneE S Sporulation inhibitor of replication protein sirA
MHKHGFKK_02092 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHKHGFKK_02093 2.8e-32 ynzC S UPF0291 protein
MHKHGFKK_02094 5.9e-212 L Transposase
MHKHGFKK_02095 9e-07
MHKHGFKK_02096 1.7e-110 tdk 2.7.1.21 F thymidine kinase
MHKHGFKK_02097 2.2e-33 rpmE J Ribosomal protein L31
MHKHGFKK_02098 2.7e-230 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MHKHGFKK_02099 7.8e-177 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MHKHGFKK_02100 5.6e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHKHGFKK_02101 4.4e-115 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MHKHGFKK_02102 3.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MHKHGFKK_02103 6e-61 spo0F T response regulator
MHKHGFKK_02104 1.3e-210
MHKHGFKK_02105 2.3e-148
MHKHGFKK_02106 4.9e-125 yhcG V ABC transporter, ATP-binding protein
MHKHGFKK_02107 2.7e-67 K helix_turn_helix gluconate operon transcriptional repressor
MHKHGFKK_02108 2.2e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHKHGFKK_02109 2.7e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MHKHGFKK_02110 9.2e-124 V ATPases associated with a variety of cellular activities
MHKHGFKK_02111 0.0 S FtsX-like permease family
MHKHGFKK_02112 0.0 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MHKHGFKK_02113 4.4e-112 kstR2_2 K Transcriptional regulator
MHKHGFKK_02114 1.8e-212 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MHKHGFKK_02115 3.7e-210 mmgC I acyl-CoA dehydrogenase
MHKHGFKK_02116 9.4e-217 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
MHKHGFKK_02118 0.0 fadF C COG0247 Fe-S oxidoreductase
MHKHGFKK_02119 7.8e-219 cls I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MHKHGFKK_02120 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MHKHGFKK_02121 1.4e-72 ywiB S Domain of unknown function (DUF1934)
MHKHGFKK_02122 2.1e-168 speB 3.5.3.11 E Belongs to the arginase family
MHKHGFKK_02123 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MHKHGFKK_02124 3.1e-92 ywhD S YwhD family
MHKHGFKK_02125 7.8e-120 ywhC S Peptidase M50
MHKHGFKK_02126 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MHKHGFKK_02127 2.3e-90 ywgA 2.1.1.72, 3.1.21.3
MHKHGFKK_02128 6.1e-257 ywfO S COG1078 HD superfamily phosphohydrolases
MHKHGFKK_02129 6.3e-99 rsfA S Transcriptional regulator
MHKHGFKK_02130 6.1e-154 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MHKHGFKK_02131 3e-176 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MHKHGFKK_02132 4.7e-145 ywfI C May function as heme-dependent peroxidase
MHKHGFKK_02133 2.2e-81 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MHKHGFKK_02134 2.8e-58 ywdK S small membrane protein
MHKHGFKK_02135 1.9e-34 S Family of unknown function (DUF5327)
MHKHGFKK_02136 3.8e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHKHGFKK_02137 3.3e-53 S Heat induced stress protein YflT
MHKHGFKK_02139 8.7e-158 L Archaeal putative transposase ISC1217
MHKHGFKK_02140 3.5e-19 S Circ_ocin_uber circular bacteriocin, circularin A uberolysin family protein
MHKHGFKK_02141 2.1e-291
MHKHGFKK_02142 2.7e-43 S Stage II sporulation protein M
MHKHGFKK_02143 2.8e-120 V ATPases associated with a variety of cellular activities
MHKHGFKK_02146 1.3e-21
MHKHGFKK_02147 0.0 ppc 4.1.1.31 C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MHKHGFKK_02149 9.9e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MHKHGFKK_02150 8.3e-75 yabE S 3D domain
MHKHGFKK_02151 7e-98 relA_2 2.7.6.5, 3.1.7.2 KT HD domain
MHKHGFKK_02152 0.0 pip S YhgE Pip N-terminal domain protein
MHKHGFKK_02153 3.7e-48 yqgV S Thiamine-binding protein
MHKHGFKK_02154 2.1e-196 pgl 3.1.1.31 G 6-phosphogluconolactonase
MHKHGFKK_02155 0.0 S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MHKHGFKK_02156 0.0 levR K PTS system fructose IIA component
MHKHGFKK_02157 2.4e-84 manX 2.7.1.191 G PTS system sorbose subfamily IIB component
MHKHGFKK_02158 2.4e-178 manL 2.7.1.191 G PTS system mannose fructose sorbose family
MHKHGFKK_02159 3.6e-119 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MHKHGFKK_02160 1.9e-169 manN G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MHKHGFKK_02161 9.1e-65 manO S Domain of unknown function (DUF956)
MHKHGFKK_02162 1.1e-211 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MHKHGFKK_02163 2.7e-282 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MHKHGFKK_02164 4.5e-166 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MHKHGFKK_02165 1.8e-81 S Heat induced stress protein YflT
MHKHGFKK_02166 5.1e-276 nylA 3.5.1.4 J Belongs to the amidase family
MHKHGFKK_02168 4.5e-120 M1-594 S Thiamine-binding protein
MHKHGFKK_02169 1.3e-140 ssuC_1 P binding-protein-dependent transport systems inner membrane component
MHKHGFKK_02170 2.3e-187 M1-596 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MHKHGFKK_02171 1.6e-140 P ABC transporter, ATP-binding protein
MHKHGFKK_02172 2.4e-167 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHKHGFKK_02173 6.3e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MHKHGFKK_02174 4.9e-243 hom 1.1.1.3 E homoserine dehydrogenase
MHKHGFKK_02175 1.5e-149 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MHKHGFKK_02176 2.1e-24 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MHKHGFKK_02177 1.5e-17 S Protein of unknown function (DUF4064)
MHKHGFKK_02178 1.2e-288 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHKHGFKK_02179 5.7e-166 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MHKHGFKK_02180 3.6e-47 yhdT S Sodium pantothenate symporter
MHKHGFKK_02181 6.5e-236 panF H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHKHGFKK_02184 1.4e-170 corA P Mg2 transporter protein CorA family protein
MHKHGFKK_02185 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MHKHGFKK_02187 3.3e-211 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MHKHGFKK_02188 2.2e-85
MHKHGFKK_02189 1.1e-77 lytE CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHKHGFKK_02190 1.3e-139 map 3.4.11.18 E Methionine aminopeptidase
MHKHGFKK_02192 1.4e-99 bioY S Biotin biosynthesis protein
MHKHGFKK_02193 2.3e-63 cueR K transcriptional
MHKHGFKK_02194 2.2e-295 6.2.1.3, 6.2.1.34 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHKHGFKK_02195 0.0 aidB I Acyl-CoA dehydrogenase, middle domain
MHKHGFKK_02196 3.9e-136 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKHGFKK_02197 6.9e-158 aacC 2.3.1.81 V aminoglycoside
MHKHGFKK_02198 2.4e-237 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHKHGFKK_02199 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
MHKHGFKK_02200 3.3e-53
MHKHGFKK_02201 1.3e-90 V ABC transporter
MHKHGFKK_02203 1.4e-24
MHKHGFKK_02204 5.7e-175 yhfP 1.1.1.1 C Quinone oxidoreductase
MHKHGFKK_02205 1.7e-159 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHKHGFKK_02206 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MHKHGFKK_02208 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
MHKHGFKK_02209 1.2e-85
MHKHGFKK_02210 7.1e-147 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MHKHGFKK_02211 2e-132 IQ Short-chain dehydrogenase reductase sdr
MHKHGFKK_02212 3e-28 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MHKHGFKK_02213 5.2e-110 cyoC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MHKHGFKK_02214 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHKHGFKK_02215 1e-157 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MHKHGFKK_02216 4.4e-123 yhcW 5.4.2.6 S hydrolase
MHKHGFKK_02217 3.4e-166 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MHKHGFKK_02218 8e-20 V COG0577 ABC-type antimicrobial peptide transport system, permease component
MHKHGFKK_02219 3.9e-36 csfB S Inhibitor of sigma-G Gin
MHKHGFKK_02220 5.1e-21 S Zinc-ribbon containing domain
MHKHGFKK_02221 9e-298 yvfH C L-lactate permease
MHKHGFKK_02222 1.1e-122 yvfI K COG2186 Transcriptional regulators
MHKHGFKK_02223 3.5e-227 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHKHGFKK_02224 7.3e-59
MHKHGFKK_02227 1.3e-168 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MHKHGFKK_02228 1.4e-218 EGP Major facilitator Superfamily
MHKHGFKK_02229 4.2e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MHKHGFKK_02230 2.2e-16 S YvrJ protein family
MHKHGFKK_02231 9.8e-11 S Protein of unknown function (DUF2922)
MHKHGFKK_02232 5.8e-11 S Protein of unknown function (DUF1659)
MHKHGFKK_02233 0.0 O Belongs to the peptidase S8 family
MHKHGFKK_02234 3.3e-68 S Protein of unknown function (DUF2512)
MHKHGFKK_02235 9.4e-50 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MHKHGFKK_02236 7.7e-52 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
MHKHGFKK_02237 1.9e-81
MHKHGFKK_02238 8.2e-249 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHKHGFKK_02239 2e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHKHGFKK_02240 0.0 2.7.1.202 K transcriptional regulator, MtlR
MHKHGFKK_02241 1.7e-156 kdsA 2.5.1.55 M Belongs to the KdsA family
MHKHGFKK_02242 1.1e-173 kdsD 5.3.1.13 M Belongs to the SIS family. GutQ KpsF subfamily
MHKHGFKK_02243 5e-226 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MHKHGFKK_02244 7.2e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MHKHGFKK_02246 0.0 treP 2.4.1.64 GH65 G Glycoside hydrolase, family 65
MHKHGFKK_02247 4.2e-147 G Binding-protein-dependent transport system inner membrane component
MHKHGFKK_02248 2e-217 sugA G Binding-protein-dependent transport system inner membrane component
MHKHGFKK_02249 7.3e-228 G Bacterial extracellular solute-binding protein
MHKHGFKK_02250 7e-133 K helix_turn_helix, arabinose operon control protein
MHKHGFKK_02251 1e-136 gumM 2.4.1.187, 2.4.1.252 GT26,GT4 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MHKHGFKK_02252 4.1e-23 S Iron-sulphur cluster biosynthesis
MHKHGFKK_02253 1.9e-104 S PFAM Uncharacterised protein family UPF0236
MHKHGFKK_02254 3.1e-150 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
MHKHGFKK_02255 2.9e-136 yflN_1 S Metallo-beta-lactamase superfamily
MHKHGFKK_02256 7.7e-293 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MHKHGFKK_02257 1.8e-85 comM O Mg chelatase subunit ChlI
MHKHGFKK_02258 4.2e-32
MHKHGFKK_02259 4.6e-311 K COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MHKHGFKK_02260 1.1e-182 S Protein of unknown function (DUF917)
MHKHGFKK_02261 5.6e-294 apc3 3.5.2.9 EQ Hydantoinase oxoprolinase
MHKHGFKK_02262 2.3e-208 codB F cytosine purines uracil thiamine allantoin
MHKHGFKK_02263 1.3e-204 S Protein of unknown function (DUF917)
MHKHGFKK_02264 1e-290 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase
MHKHGFKK_02265 3.9e-176 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MHKHGFKK_02266 5.1e-65 yjbR S YjbR
MHKHGFKK_02267 6.2e-64 S Protein of unknown function (DUF1648)
MHKHGFKK_02268 1.6e-244 L Metallo-beta-lactamase superfamily
MHKHGFKK_02269 4.6e-29 S Protein of unknown function (DUF3006)
MHKHGFKK_02270 0.0 L Metal dependent phosphohydrolases with conserved 'HD' motif.
MHKHGFKK_02271 6.3e-114 S CRISPR-associated protein
MHKHGFKK_02272 8.2e-299 csd1 S CRISPR-associated protein (Cas_Csd1)
MHKHGFKK_02273 1.9e-164 csd2 L CRISPR-associated protein Cas7
MHKHGFKK_02274 5.7e-13 cmr6 L TIGRFAM CRISPR-associated RAMP protein, Cmr6 family
MHKHGFKK_02275 1e-26
MHKHGFKK_02276 0.0 ybeC E amino acid
MHKHGFKK_02277 0.0 3.2.1.78 GH26 O cellulase activity
MHKHGFKK_02278 4.6e-177 K cell envelope-related transcriptional attenuator
MHKHGFKK_02279 9.5e-51
MHKHGFKK_02281 6.5e-173 ydhF S Oxidoreductase
MHKHGFKK_02282 3.5e-155 S transposase or invertase
MHKHGFKK_02284 1.4e-53 S Domain of unknown function (DUF3870)
MHKHGFKK_02285 3.3e-233 B4168_2380 1.3.99.32 I Acyl-CoA dehydrogenase, N-terminal domain
MHKHGFKK_02286 1e-223 C acyl-CoA transferases carnitine dehydratase
MHKHGFKK_02287 1.5e-191 yfmJ S N-terminal domain of oxidoreductase
MHKHGFKK_02288 2.4e-215 EGP Major facilitator Superfamily
MHKHGFKK_02289 0.0 2.7.1.202 K transcriptional regulator, MtlR
MHKHGFKK_02290 4.2e-53 licB 2.7.1.196, 2.7.1.205 G phosphotransferase system
MHKHGFKK_02291 1.6e-52 chbA 2.7.1.196, 2.7.1.205 G PTS cellobiose transporter subunit IIA
MHKHGFKK_02292 1.8e-206 S Bacterial protein of unknown function (DUF871)
MHKHGFKK_02293 1.7e-232 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHKHGFKK_02294 3.2e-99 gph G MFS/sugar transport protein
MHKHGFKK_02295 1.7e-50 L Transposase
MHKHGFKK_02296 4.3e-42 S COG NOG14552 non supervised orthologous group
MHKHGFKK_02297 4.3e-49
MHKHGFKK_02298 1e-145 G PFAM Phosphotransferase system, mannose fructose sorbose family IID component
MHKHGFKK_02299 1e-129 G PTS system sorbose-specific iic component
MHKHGFKK_02300 9.7e-83 2.7.1.191 G PTS system sorbose subfamily IIB component
MHKHGFKK_02301 1.2e-71 2.7.1.191 G PTS system fructose IIA component
MHKHGFKK_02302 3.2e-107 K PFAM sigma-54 factor interaction domain-containing protein
MHKHGFKK_02303 1.2e-266 K PTS system fructose IIA component
MHKHGFKK_02304 2.4e-42 K Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MHKHGFKK_02305 1.5e-09 L DDE superfamily endonuclease
MHKHGFKK_02307 1e-53 3.5.1.19 Q Isochorismatase family
MHKHGFKK_02308 5.7e-94 S S4 RNA-binding domain
MHKHGFKK_02309 3.7e-185
MHKHGFKK_02310 8.1e-51 yxjI S LURP-one-related
MHKHGFKK_02311 1.1e-158 yitS S protein conserved in bacteria
MHKHGFKK_02312 2.2e-25 S Protein of unknown function (DUF3813)
MHKHGFKK_02313 4.2e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MHKHGFKK_02314 9.5e-52 yitW S metal-sulfur cluster biosynthetic enzyme
MHKHGFKK_02315 6.2e-27 yjzC S YjzC-like protein
MHKHGFKK_02316 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHKHGFKK_02318 1.4e-144 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
MHKHGFKK_02320 5.6e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHKHGFKK_02321 7.3e-236 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHKHGFKK_02322 1.8e-150 yjaZ O Zn-dependent protease
MHKHGFKK_02323 1.8e-192 oppD P Belongs to the ABC transporter superfamily
MHKHGFKK_02324 1.3e-176 oppF P Belongs to the ABC transporter superfamily
MHKHGFKK_02325 1.7e-168 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHKHGFKK_02326 2.2e-133 oppC EP binding-protein-dependent transport systems inner membrane component
MHKHGFKK_02327 0.0 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
MHKHGFKK_02328 2.4e-53 S FAD binding domain
MHKHGFKK_02331 1e-156 galM 5.1.3.3 G Aldose 1-epimerase
MHKHGFKK_02332 0.0 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MHKHGFKK_02333 3e-90 S LXG domain of WXG superfamily
MHKHGFKK_02334 3.3e-30 S LXG domain of WXG superfamily
MHKHGFKK_02335 1.7e-188 mcrC V McrBC 5-methylcytosine restriction system component
MHKHGFKK_02336 0.0 mcrB V AAA domain (dynein-related subfamily)
MHKHGFKK_02337 0.0 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
MHKHGFKK_02338 1.3e-85 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
MHKHGFKK_02339 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
MHKHGFKK_02340 1.5e-26
MHKHGFKK_02341 9.7e-115 E LysE type translocator
MHKHGFKK_02342 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MHKHGFKK_02343 1.1e-78 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MHKHGFKK_02344 5.7e-255 3.2.1.122, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MHKHGFKK_02345 3.8e-285 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MHKHGFKK_02346 1.6e-129 K Helix-turn-helix domain, rpiR family
MHKHGFKK_02347 3.8e-113 mleP S Membrane transport protein
MHKHGFKK_02348 1.5e-19 mleP S auxin efflux carrier
MHKHGFKK_02349 3.8e-256 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme, NAD binding domain
MHKHGFKK_02350 4.1e-148 mleR K LysR substrate binding domain
MHKHGFKK_02351 3.7e-118 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKHGFKK_02352 3.1e-218 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHKHGFKK_02353 3.8e-84 nrdG 1.97.1.4 O 4Fe-4S single cluster domain
MHKHGFKK_02354 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MHKHGFKK_02355 5.4e-195 U protein localization to endoplasmic reticulum
MHKHGFKK_02356 4.3e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MHKHGFKK_02357 6.5e-73 KT Sugar diacid utilization regulator
MHKHGFKK_02358 3.6e-191 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MHKHGFKK_02359 3.6e-161 EG Gluconate proton symporter
MHKHGFKK_02360 1.5e-153 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MHKHGFKK_02361 6.1e-150 rbsC G Belongs to the binding-protein-dependent transport system permease family
MHKHGFKK_02362 2.4e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MHKHGFKK_02363 3.2e-68 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MHKHGFKK_02364 1.7e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHKHGFKK_02365 4.3e-239 rbsR K transcriptional
MHKHGFKK_02366 1.4e-09 S transposase or invertase
MHKHGFKK_02367 7e-151 S transposase or invertase
MHKHGFKK_02369 2.4e-102 ycnI S Domain of unkown function (DUF1775)
MHKHGFKK_02371 5.4e-303 ycnJ P protein, homolog of Cu resistance protein CopC
MHKHGFKK_02373 4.7e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHKHGFKK_02374 5.2e-119 5.1.3.1 G Ribulose-phosphate 3 epimerase family
MHKHGFKK_02375 2.3e-179 rbsR K transcriptional
MHKHGFKK_02376 5.2e-257 G PTS system sugar-specific permease component
MHKHGFKK_02377 5.8e-78 G Transmembrane secretion effector
MHKHGFKK_02378 4.3e-66 S Putative restriction endonuclease
MHKHGFKK_02379 2.2e-95
MHKHGFKK_02380 4.1e-41
MHKHGFKK_02381 3.1e-23 S Immunity protein Imm6
MHKHGFKK_02382 1.1e-42 L PFAM Transposase, IS4-like
MHKHGFKK_02383 3e-289 L Transposase
MHKHGFKK_02384 2.8e-226 mtlF 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
MHKHGFKK_02385 1.4e-167 mtlR K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHKHGFKK_02386 2.1e-136 mtlD 1.1.1.17 G Mannitol dehydrogenase Rossmann domain
MHKHGFKK_02387 3e-231 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MHKHGFKK_02388 2e-107 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MHKHGFKK_02389 2.3e-38 gcvR T Belongs to the UPF0237 family
MHKHGFKK_02390 9.1e-248 XK27_08635 S UPF0210 protein
MHKHGFKK_02391 6.4e-193 ptxS K transcriptional
MHKHGFKK_02392 7.5e-135 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
MHKHGFKK_02393 1.8e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MHKHGFKK_02394 2.3e-240 G Major Facilitator Superfamily
MHKHGFKK_02395 5.9e-93 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
MHKHGFKK_02396 1.4e-93 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M SIS domain
MHKHGFKK_02398 6.8e-84 cotF M Spore coat protein
MHKHGFKK_02399 1.4e-175 iolS C Aldo keto reductase
MHKHGFKK_02400 8.5e-99 ydjA C Nitroreductase family
MHKHGFKK_02401 7.2e-253 E COG1113 Gamma-aminobutyrate permease and related permeases
MHKHGFKK_02402 8.5e-17
MHKHGFKK_02403 9.6e-275 dtpT E amino acid peptide transporter
MHKHGFKK_02404 3.3e-175 lysP E amino acid
MHKHGFKK_02405 1.2e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MHKHGFKK_02408 5.9e-191 T HD domain
MHKHGFKK_02409 8.6e-278 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
MHKHGFKK_02411 0.0 ydaO E amino acid
MHKHGFKK_02412 1.6e-146 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHKHGFKK_02413 3e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MHKHGFKK_02414 1.1e-173 ydbI S AI-2E family transporter
MHKHGFKK_02415 1.5e-132 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MHKHGFKK_02416 1.3e-135 glnH ET Belongs to the bacterial solute-binding protein 3 family
MHKHGFKK_02417 1.2e-109 gluC P ABC transporter
MHKHGFKK_02418 2.3e-117 glnP P ABC transporter
MHKHGFKK_02419 1.7e-69 K helix_turn_helix gluconate operon transcriptional repressor
MHKHGFKK_02420 1.2e-197 S Protein of unknown function (DUF1648)
MHKHGFKK_02421 9.6e-55 yodB K transcriptional
MHKHGFKK_02423 2.2e-235 S SNARE associated Golgi protein
MHKHGFKK_02424 4.2e-96 yngC S membrane-associated protein
MHKHGFKK_02425 9.5e-159 msrR K COG1316 Transcriptional regulator
MHKHGFKK_02427 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MHKHGFKK_02428 0.0 metH 2.1.1.13 E Methionine synthase
MHKHGFKK_02429 3.4e-12 csbD S Belongs to the UPF0337 (CsbD) family
MHKHGFKK_02430 2.2e-87 K ComK protein
MHKHGFKK_02431 8.4e-97 sigS 2.7.7.6 K Belongs to the sigma-70 factor family. ECF subfamily
MHKHGFKK_02432 1.2e-149 E lipolytic protein G-D-S-L family
MHKHGFKK_02433 2.2e-123 ywqC M biosynthesis protein
MHKHGFKK_02434 8.8e-112 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MHKHGFKK_02435 2.3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MHKHGFKK_02436 1.9e-156 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MHKHGFKK_02437 7.3e-92 cpsE M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MHKHGFKK_02438 2e-153 fcl 1.1.1.271 GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
MHKHGFKK_02439 1.1e-184 gmd 4.2.1.47 M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MHKHGFKK_02440 1.3e-22 exoQ M PFAM O-Antigen ligase
MHKHGFKK_02441 2.8e-60 rfbX S PFAM polysaccharide biosynthesis protein
MHKHGFKK_02442 7.7e-34 S Glycosyl transferase family 2
MHKHGFKK_02443 8.8e-24 2.3.1.157, 2.3.1.79, 2.7.7.23 S Bacterial transferase hexapeptide (six repeats)
MHKHGFKK_02444 1.9e-25 M Glycosyltransferase Family 4
MHKHGFKK_02445 6.3e-21 M Glycosyl transferases group 1
MHKHGFKK_02446 1.5e-121 rfaG3 M Glycosyltransferase Family 4
MHKHGFKK_02447 1.1e-86 wecG 2.4.1.187 GT26 M Belongs to the glycosyltransferase 26 family
MHKHGFKK_02448 3.1e-203 manC 2.7.7.13, 5.3.1.8 G mannose-1-phosphate guanylyltransferase
MHKHGFKK_02449 1.1e-272 L Transposase
MHKHGFKK_02450 9.7e-79 L PFAM transposase IS4 family protein
MHKHGFKK_02451 1.8e-65
MHKHGFKK_02452 2.7e-52 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MHKHGFKK_02453 8.7e-284 xylB 2.7.1.12, 2.7.1.17 G xylulose kinase
MHKHGFKK_02454 0.0 M Peptidase M30
MHKHGFKK_02455 5.9e-53 croE S Helix-turn-helix
MHKHGFKK_02456 1.2e-27 E IrrE N-terminal-like domain
MHKHGFKK_02457 1.6e-39 E IrrE N-terminal-like domain
MHKHGFKK_02458 3.3e-46 L COG2963 Transposase and inactivated derivatives
MHKHGFKK_02459 3.5e-154 L COG2801 Transposase and inactivated derivatives
MHKHGFKK_02460 1.6e-121 S Antitoxin Phd_YefM, type II toxin-antitoxin system
MHKHGFKK_02461 6e-133 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHKHGFKK_02462 1.9e-130 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MHKHGFKK_02463 5.7e-24 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MHKHGFKK_02464 2.1e-205 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MHKHGFKK_02465 8.1e-73 fliJ N Flagellar biosynthesis chaperone
MHKHGFKK_02466 1.3e-47 ylxF S MgtE intracellular N domain
MHKHGFKK_02467 0.0 fliK N Flagellar hook-length control
MHKHGFKK_02468 5.7e-107 flgD N Required for flagellar hook formation. May act as a scaffolding protein
MHKHGFKK_02469 7.4e-77 flg N Putative flagellar
MHKHGFKK_02470 2.2e-134 flgG N Flagellar basal body rod
MHKHGFKK_02471 9.3e-66 fliL N Controls the rotational direction of flagella during chemotaxis
MHKHGFKK_02472 9.9e-183 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHKHGFKK_02473 4.3e-195 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MHKHGFKK_02474 3.2e-59 cheB 3.1.1.61, 3.5.1.44 T response regulator
MHKHGFKK_02475 1.1e-116 fliZ N Flagellar biosynthesis protein, FliO
MHKHGFKK_02476 2e-107 fliP N Plays a role in the flagellum-specific transport system
MHKHGFKK_02477 1.5e-37 fliQ N Role in flagellar biosynthesis
MHKHGFKK_02478 2.5e-133 fliR N Flagellar biosynthetic protein FliR
MHKHGFKK_02479 3.4e-189 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHKHGFKK_02480 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHKHGFKK_02481 8.4e-207 flhF N Flagellar biosynthesis regulator FlhF
MHKHGFKK_02482 3e-156 flhG D Belongs to the ParA family
MHKHGFKK_02483 9.6e-118 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MHKHGFKK_02484 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MHKHGFKK_02485 3.1e-69 cheW NT COG0835 Chemotaxis signal transduction protein
MHKHGFKK_02486 4e-113 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MHKHGFKK_02487 8.1e-85 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MHKHGFKK_02488 1.8e-136 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHKHGFKK_02489 8e-86 ylxL
MHKHGFKK_02490 6.2e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
MHKHGFKK_02491 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHKHGFKK_02492 1.5e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MHKHGFKK_02493 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHKHGFKK_02494 1.6e-148 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHKHGFKK_02495 2.9e-145 cdsA 2.7.7.41 S Belongs to the CDS family
MHKHGFKK_02496 5.2e-212 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MHKHGFKK_02497 7.4e-236 rasP M zinc metalloprotease
MHKHGFKK_02498 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHKHGFKK_02499 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHKHGFKK_02500 9.2e-83 rimP S Required for maturation of 30S ribosomal subunits
MHKHGFKK_02501 4.4e-222 nusA K Participates in both transcription termination and antitermination
MHKHGFKK_02502 8.2e-45 ylxR K nucleic-acid-binding protein implicated in transcription termination
MHKHGFKK_02503 2.9e-48 ylxQ J ribosomal protein
MHKHGFKK_02504 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHKHGFKK_02505 1.1e-43 ylxP S protein conserved in bacteria
MHKHGFKK_02506 3.2e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHKHGFKK_02507 5.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHKHGFKK_02508 3.8e-184 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MHKHGFKK_02509 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHKHGFKK_02510 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MHKHGFKK_02511 5.2e-209 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MHKHGFKK_02512 5.2e-234 pepR S Belongs to the peptidase M16 family
MHKHGFKK_02513 6.2e-38 ymxH S YlmC YmxH family
MHKHGFKK_02514 1.3e-190 dpaA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MHKHGFKK_02515 3.7e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MHKHGFKK_02516 9.6e-189 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHKHGFKK_02517 2.4e-223 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MHKHGFKK_02518 3.6e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHKHGFKK_02519 2.3e-311 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHKHGFKK_02520 2e-132 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MHKHGFKK_02521 3.3e-35 S YlzJ-like protein
MHKHGFKK_02522 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MHKHGFKK_02523 1.5e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MHKHGFKK_02524 1.3e-287 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MHKHGFKK_02525 2e-186 yufP S Belongs to the binding-protein-dependent transport system permease family
MHKHGFKK_02526 2.4e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
MHKHGFKK_02527 6.1e-238 ymfF S Peptidase M16
MHKHGFKK_02528 1.2e-244 ymfH S zinc protease
MHKHGFKK_02529 4.2e-144 1.1.1.100 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MHKHGFKK_02530 1.6e-39 ymfJ S Protein of unknown function (DUF3243)
MHKHGFKK_02531 9.9e-146 ymfK S Protein of unknown function (DUF3388)
MHKHGFKK_02532 4.5e-156 ymfM S protein conserved in bacteria
MHKHGFKK_02533 1.6e-100 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHKHGFKK_02534 2.1e-227 cinA 3.5.1.42 S Belongs to the CinA family
MHKHGFKK_02535 2.1e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHKHGFKK_02536 2.5e-217 rny S Endoribonuclease that initiates mRNA decay
MHKHGFKK_02537 6.5e-153 ymdB S protein conserved in bacteria
MHKHGFKK_02538 3.3e-37 spoVS S Stage V sporulation protein S
MHKHGFKK_02539 6e-171 yegQ O Peptidase U32
MHKHGFKK_02540 2.6e-249 yegQ O COG0826 Collagenase and related proteases
MHKHGFKK_02541 1.1e-250 E Amino acid permease
MHKHGFKK_02542 0.0 KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MHKHGFKK_02543 2.8e-290 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MHKHGFKK_02544 1.4e-264 patA 2.6.1.11, 2.6.1.17, 2.6.1.82 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHKHGFKK_02545 6.8e-300 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MHKHGFKK_02546 6.8e-48 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MHKHGFKK_02547 3.6e-99 cotE S Outer spore coat protein E (CotE)
MHKHGFKK_02548 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHKHGFKK_02549 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHKHGFKK_02550 5.7e-37 yhjA S Excalibur calcium-binding domain
MHKHGFKK_02551 1.6e-31 2.1.1.80, 3.1.1.61 S protein secretion by the type IV secretion system
MHKHGFKK_02554 2e-194 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHKHGFKK_02555 1.2e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MHKHGFKK_02557 4.2e-175 spoVK O stage V sporulation protein K
MHKHGFKK_02558 2.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHKHGFKK_02559 4e-245 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MHKHGFKK_02560 1.1e-169 polA 2.7.7.7 L 5'3' exonuclease
MHKHGFKK_02562 3.6e-27 ypeQ S Zinc-finger
MHKHGFKK_02563 1.2e-31 cspD K Cold-shock protein
MHKHGFKK_02564 1.2e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MHKHGFKK_02565 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MHKHGFKK_02566 8.9e-84
MHKHGFKK_02567 7.7e-120 ypgQ S phosphohydrolase
MHKHGFKK_02568 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHKHGFKK_02569 8.3e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
MHKHGFKK_02570 5.6e-74 yphP S Belongs to the UPF0403 family
MHKHGFKK_02571 8.1e-105 ypjP S YpjP-like protein
MHKHGFKK_02572 3.1e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHKHGFKK_02573 3.9e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHKHGFKK_02574 1.9e-110 hlyIII S protein, Hemolysin III
MHKHGFKK_02575 1.8e-139 ypmR E COG2755 Lysophospholipase L1 and related esterases
MHKHGFKK_02576 3e-96 ypmS S protein conserved in bacteria
MHKHGFKK_02577 3e-267 rsmF 2.1.1.176, 2.1.1.178 J RNA-binding PUA-like domain of methyltransferase RsmF
MHKHGFKK_02578 6e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHKHGFKK_02579 7.3e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MHKHGFKK_02580 9e-16 S Protein of unknown function (Tiny_TM_bacill)
MHKHGFKK_02581 3e-206 NT CHASE3 domain
MHKHGFKK_02582 3e-36 yozE S Belongs to the UPF0346 family
MHKHGFKK_02583 1.5e-115 yodN
MHKHGFKK_02584 1.3e-24 yozD S YozD-like protein
MHKHGFKK_02586 6.9e-147 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MHKHGFKK_02587 1.1e-278 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MHKHGFKK_02588 2.4e-69 ypoP K transcriptional
MHKHGFKK_02589 1e-99 ykwD J protein with SCP PR1 domains
MHKHGFKK_02590 2.4e-248 norM V Multidrug efflux pump
MHKHGFKK_02592 8.3e-190 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHKHGFKK_02593 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MHKHGFKK_02594 4.6e-133 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MHKHGFKK_02595 6.3e-106 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MHKHGFKK_02597 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MHKHGFKK_02598 2.3e-104 K Transcriptional regulator
MHKHGFKK_02599 5.4e-59 4.4.1.5 E lactoylglutathione lyase activity
MHKHGFKK_02600 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MHKHGFKK_02601 3.9e-229 ymfD EGP Major facilitator Superfamily
MHKHGFKK_02602 1.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKHGFKK_02603 1.2e-255 arlS 2.7.13.3 T Histidine kinase
MHKHGFKK_02604 4.9e-81 yozR S COG0071 Molecular chaperone (small heat shock protein)
MHKHGFKK_02605 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MHKHGFKK_02606 3.5e-209 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MHKHGFKK_02607 7.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MHKHGFKK_02608 5.9e-92 rok S Repressor of ComK
MHKHGFKK_02609 7.5e-114 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHKHGFKK_02611 4.2e-161 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MHKHGFKK_02612 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHKHGFKK_02613 1.3e-192 yceA S Belongs to the UPF0176 family
MHKHGFKK_02614 8e-128 yoqW S Belongs to the SOS response-associated peptidase family
MHKHGFKK_02615 1.6e-103 thiT S Proton-coupled thiamine transporter YuaJ
MHKHGFKK_02616 3.1e-169 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MHKHGFKK_02617 2.1e-79 S Domain in cystathionine beta-synthase and other proteins.
MHKHGFKK_02618 2.5e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MHKHGFKK_02619 9.1e-107 yocH CBM50 M COG1388 FOG LysM repeat
MHKHGFKK_02620 0.0 topB2 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHKHGFKK_02621 1.7e-254 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MHKHGFKK_02622 2.6e-112 E Lysine exporter protein LysE YggA
MHKHGFKK_02623 2.4e-178 corA P Mg2 transporter protein
MHKHGFKK_02624 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MHKHGFKK_02625 1.7e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHKHGFKK_02626 1.7e-108 rplD J Forms part of the polypeptide exit tunnel
MHKHGFKK_02627 1.7e-42 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHKHGFKK_02628 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHKHGFKK_02629 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHKHGFKK_02630 1.9e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHKHGFKK_02631 2.3e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHKHGFKK_02632 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHKHGFKK_02633 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
MHKHGFKK_02634 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHKHGFKK_02635 1.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHKHGFKK_02636 1.7e-57 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHKHGFKK_02637 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHKHGFKK_02638 5.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHKHGFKK_02639 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHKHGFKK_02640 6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHKHGFKK_02641 6.1e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHKHGFKK_02642 4.7e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHKHGFKK_02643 7e-23 rpmD J Ribosomal protein L30
MHKHGFKK_02644 1.2e-71 rplO J binds to the 23S rRNA
MHKHGFKK_02645 1.4e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHKHGFKK_02646 1.7e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHKHGFKK_02647 2.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHKHGFKK_02648 1.8e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHKHGFKK_02649 5.2e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHKHGFKK_02650 6.9e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHKHGFKK_02651 2.8e-59 rplQ J Ribosomal protein L17
MHKHGFKK_02653 2.7e-157 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHKHGFKK_02654 6.4e-162 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHKHGFKK_02655 6e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHKHGFKK_02656 2.8e-134 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHKHGFKK_02657 9.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHKHGFKK_02658 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MHKHGFKK_02659 3.5e-24 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MHKHGFKK_02660 0.0 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MHKHGFKK_02661 0.0 S type I phosphodiesterase nucleotide pyrophosphatase
MHKHGFKK_02663 1.3e-226 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MHKHGFKK_02664 2e-109 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MHKHGFKK_02665 1.9e-275 lysP E amino acid
MHKHGFKK_02666 8.8e-83 ybaK S Protein of unknown function (DUF2521)
MHKHGFKK_02667 6.2e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MHKHGFKK_02668 1.9e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MHKHGFKK_02669 4.8e-70 gerD S Spore gernimation protein
MHKHGFKK_02670 1.3e-108 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MHKHGFKK_02671 8.7e-217 S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
MHKHGFKK_02672 5.5e-138 pdaB 3.5.1.104 G xylanase chitin deacetylase
MHKHGFKK_02673 2.6e-30
MHKHGFKK_02674 1.3e-262 cydA 1.10.3.14 C oxidase, subunit
MHKHGFKK_02675 8.4e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MHKHGFKK_02676 0.0 cydD V ATP-binding
MHKHGFKK_02677 0.0 cydD V ATP-binding protein
MHKHGFKK_02678 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
MHKHGFKK_02679 1.6e-241 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHKHGFKK_02680 2.9e-303 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MHKHGFKK_02681 6.9e-120 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHKHGFKK_02682 2.2e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MHKHGFKK_02683 9.6e-186 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHKHGFKK_02684 1.5e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHKHGFKK_02685 8.7e-40 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MHKHGFKK_02686 1.2e-244 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MHKHGFKK_02688 1.3e-07 S Heavy-metal-associated domain
MHKHGFKK_02689 2.2e-85 S Protein of unknown function (DUF1641)
MHKHGFKK_02690 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
MHKHGFKK_02691 3.8e-31
MHKHGFKK_02693 8e-80 NT chemotaxis protein
MHKHGFKK_02694 7.1e-136 NT chemotaxis protein
MHKHGFKK_02696 3.8e-19 S transposase or invertase
MHKHGFKK_02697 6e-14 S transposase or invertase
MHKHGFKK_02698 5.4e-20 S transposase or invertase
MHKHGFKK_02699 5.9e-158 S transposase or invertase
MHKHGFKK_02700 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MHKHGFKK_02701 4.3e-86 uspF T Universal stress protein
MHKHGFKK_02703 1.8e-192 ykfD E Belongs to the ABC transporter superfamily
MHKHGFKK_02704 3.5e-179 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHKHGFKK_02705 0.0 dppE E ABC transporter substrate-binding protein
MHKHGFKK_02706 1.3e-190 dppD P Belongs to the ABC transporter superfamily
MHKHGFKK_02707 1.4e-170 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHKHGFKK_02708 7.5e-161 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHKHGFKK_02709 6.2e-131 S Peptidase C26
MHKHGFKK_02710 2.5e-183 corA P Mediates influx of magnesium ions
MHKHGFKK_02711 8.8e-46 yhdB S YhdB-like protein
MHKHGFKK_02713 5.1e-278 ycgB S Stage V sporulation protein R
MHKHGFKK_02714 2.7e-185 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MHKHGFKK_02715 3.1e-135 3.2.1.18 GH33 E GDSL-like Lipase/Acylhydrolase
MHKHGFKK_02716 3.1e-77 bdbC O Required for disulfide bond formation in some proteins
MHKHGFKK_02717 1.4e-86 bdbA CO Thioredoxin
MHKHGFKK_02718 1.9e-89 yhcU S Family of unknown function (DUF5365)
MHKHGFKK_02719 3.3e-112 ykaA P Protein of unknown function DUF47
MHKHGFKK_02720 5e-179 pit P phosphate transporter
MHKHGFKK_02721 1.1e-103 2.3.1.128 J Acetyltransferase (GNAT) domain
MHKHGFKK_02723 9.6e-222 yhbH S Belongs to the UPF0229 family
MHKHGFKK_02724 0.0 prkA T Ser protein kinase
MHKHGFKK_02725 2.6e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHKHGFKK_02726 3.3e-166 yhbB S Putative amidase domain
MHKHGFKK_02727 2.1e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MHKHGFKK_02728 8.2e-103 yvbG U UPF0056 membrane protein
MHKHGFKK_02729 6.6e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MHKHGFKK_02730 3.7e-84 S Rubrerythrin
MHKHGFKK_02731 2.9e-167 pip 3.4.11.5, 3.5.1.101 S Releases the N-terminal proline from various substrates
MHKHGFKK_02732 2.9e-145 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MHKHGFKK_02733 1.9e-116 tcyB P COG0765 ABC-type amino acid transport system, permease component
MHKHGFKK_02734 4.5e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MHKHGFKK_02735 1.4e-74 P PFAM major facilitator superfamily MFS_1
MHKHGFKK_02736 6e-149 focA P Formate/nitrite transporter
MHKHGFKK_02737 3.9e-215 dhaT 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
MHKHGFKK_02738 0.0 pflB 2.3.1.54 C formate acetyltransferase
MHKHGFKK_02739 1.7e-144 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHKHGFKK_02740 5.8e-100 1.5.1.38 S FMN reductase
MHKHGFKK_02741 1.2e-89
MHKHGFKK_02742 2.5e-170 bcrB S ABC transporter (permease)
MHKHGFKK_02743 4.8e-168 bcrA V ABC transporter, ATP-binding protein
MHKHGFKK_02744 3.2e-144 ypmR1 E G-D-S-L family
MHKHGFKK_02745 6.2e-32
MHKHGFKK_02747 5.8e-170 S High confidence in function and specificity
MHKHGFKK_02748 1.8e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKHGFKK_02749 1.3e-249 ykoH3 T Histidine kinase
MHKHGFKK_02750 6e-109
MHKHGFKK_02751 1.7e-64 folT 2.7.13.3 T ECF transporter, substrate-specific component
MHKHGFKK_02752 2.9e-51 K UTRA domain
MHKHGFKK_02753 3.3e-69 S CHY zinc finger
MHKHGFKK_02754 2.3e-212 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MHKHGFKK_02755 1.7e-108 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MHKHGFKK_02756 2.7e-225 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHKHGFKK_02757 8.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MHKHGFKK_02758 1.5e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHKHGFKK_02759 1.1e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MHKHGFKK_02760 6.6e-139 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHKHGFKK_02761 1e-119 hisE 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MHKHGFKK_02762 5.9e-41 yedF O Belongs to the sulfur carrier protein TusA family
MHKHGFKK_02763 1.4e-239 yedE S Sulphur transport
MHKHGFKK_02764 1.2e-174 rarD S -transporter
MHKHGFKK_02765 1.7e-219 ktrB P COG0168 Trk-type K transport systems, membrane components
MHKHGFKK_02766 1.7e-122 P COG0569 K transport systems, NAD-binding component
MHKHGFKK_02767 3e-136 ykrK S Domain of unknown function (DUF1836)
MHKHGFKK_02768 1.1e-16
MHKHGFKK_02769 3.6e-48 yxcD S Protein of unknown function (DUF2653)
MHKHGFKK_02770 8.6e-218 yeaN P COG2807 Cyanate permease
MHKHGFKK_02771 0.0 ubiB S ABC1 family
MHKHGFKK_02772 2.3e-23 S ATP synthase, subunit b
MHKHGFKK_02773 7.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHKHGFKK_02775 2.7e-31 cspB K Cold shock
MHKHGFKK_02776 3.6e-117 folE 3.5.4.16 H GTP cyclohydrolase
MHKHGFKK_02777 5.1e-165 trxB_2 1.8.1.9 C FAD dependent oxidoreductase
MHKHGFKK_02778 1.8e-44 S Protein of unknown function (DUF1292)
MHKHGFKK_02779 8.1e-48 yxiS
MHKHGFKK_02780 0.0 bceB V ABC transporter (permease)
MHKHGFKK_02781 3.6e-137 bceA V ABC transporter, ATP-binding protein
MHKHGFKK_02782 1.9e-181 bceS 2.7.13.3 T Signal transduction histidine kinase
MHKHGFKK_02783 4.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKHGFKK_02784 2e-113 S Protein of unknown function (DUF1672)
MHKHGFKK_02785 1.3e-108 S Protein of unknown function (DUF1672)
MHKHGFKK_02787 1.2e-70 ybzH K Helix-turn-helix domain
MHKHGFKK_02788 4.7e-200 ybcL EGP Major facilitator Superfamily
MHKHGFKK_02790 2e-194 yxaB GM Polysaccharide pyruvyl transferase
MHKHGFKK_02791 1.3e-16
MHKHGFKK_02792 2.3e-238 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MHKHGFKK_02793 3.6e-202 yetN S Protein of unknown function (DUF3900)
MHKHGFKK_02794 1.1e-150
MHKHGFKK_02796 5.9e-239 ywoD EGP Major facilitator superfamily
MHKHGFKK_02797 2.5e-52 iscA S Heme biosynthesis protein HemY
MHKHGFKK_02798 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHKHGFKK_02799 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHKHGFKK_02800 9.4e-43 S Small, acid-soluble spore proteins, alpha/beta type
MHKHGFKK_02801 2.2e-61 S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MHKHGFKK_02802 1.6e-112 M effector of murein hydrolase
MHKHGFKK_02803 0.0 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHKHGFKK_02804 2.1e-114 M lytic transglycosylase activity
MHKHGFKK_02805 1.4e-08 S membrane
MHKHGFKK_02806 8.6e-19 sspP S Belongs to the SspP family
MHKHGFKK_02807 2.6e-39
MHKHGFKK_02808 6.4e-240 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MHKHGFKK_02809 2.6e-18 sspO S Belongs to the SspO family
MHKHGFKK_02810 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MHKHGFKK_02812 1e-19 sspN S Small acid-soluble spore protein N family
MHKHGFKK_02813 4.1e-31 tlp S Belongs to the Tlp family
MHKHGFKK_02814 2.2e-75 yneP S thioesterase
MHKHGFKK_02815 2.5e-52 yneQ
MHKHGFKK_02816 3.7e-53 yneR S Belongs to the HesB IscA family
MHKHGFKK_02817 9.6e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHKHGFKK_02818 1.9e-71 yccU S CoA-binding protein
MHKHGFKK_02819 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHKHGFKK_02820 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHKHGFKK_02821 2.8e-148
MHKHGFKK_02822 1e-47 3.6.1.55 F GDP-mannose mannosyl hydrolase activity
MHKHGFKK_02824 2.5e-226 ywdJ F Xanthine uracil
MHKHGFKK_02825 0.0 yjcD 3.6.4.12 L DNA helicase
MHKHGFKK_02826 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHKHGFKK_02828 9.4e-98 O HI0933-like protein
MHKHGFKK_02831 2.7e-79 K Acetyltransferase (GNAT) domain
MHKHGFKK_02832 1.5e-291 yngE I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MHKHGFKK_02833 1.6e-132 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MHKHGFKK_02834 9.9e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
MHKHGFKK_02835 4.8e-15 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MHKHGFKK_02836 3.7e-249 yngH 6.3.4.14, 6.3.4.6, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MHKHGFKK_02837 5e-215 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MHKHGFKK_02838 0.0 6.2.1.1 I AMP-dependent synthetase
MHKHGFKK_02839 1.9e-302 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHKHGFKK_02840 2.3e-249 zraR KT Transcriptional regulator
MHKHGFKK_02841 1.8e-231 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MHKHGFKK_02842 1e-243 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MHKHGFKK_02843 4e-78 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MHKHGFKK_02844 2.5e-272 hsdM 2.1.1.72 V Type I restriction-modification system
MHKHGFKK_02846 1.8e-207 L Integrase core domain
MHKHGFKK_02847 3.6e-137 L PhoH-like protein
MHKHGFKK_02848 1.2e-74 L Transposase DDE domain
MHKHGFKK_02849 2.5e-57 L Transposase DDE domain
MHKHGFKK_02850 5.4e-103 L PFAM Transposase, Mutator
MHKHGFKK_02851 3e-61 S Protein of unknown function (DUF4064)
MHKHGFKK_02852 1.7e-102 K Bacterial regulatory proteins, tetR family
MHKHGFKK_02853 6.2e-34 mutT 3.6.1.55 F Belongs to the Nudix hydrolase family
MHKHGFKK_02854 7.8e-83 K Transcriptional regulator
MHKHGFKK_02855 5.2e-206 EGP Sugar (and other) transporter
MHKHGFKK_02856 3.7e-86 Q dioxygenase activity
MHKHGFKK_02857 5.1e-53 K helix_turn_helix, arabinose operon control protein
MHKHGFKK_02859 1.9e-144 U Type II secretory pathway, component ExeA
MHKHGFKK_02860 1.3e-270 L PFAM Mu transposase, C-terminal
MHKHGFKK_02861 7.7e-28 hisF E Dihydrouridine synthase (Dus)
MHKHGFKK_02862 3.6e-45 L Transposase
MHKHGFKK_02863 1.7e-106 L PFAM Integrase catalytic region
MHKHGFKK_02864 4.7e-57 L PFAM Transposase, IS4-like
MHKHGFKK_02865 1.1e-15 S Ribbon-helix-helix protein, copG family
MHKHGFKK_02866 1e-57 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MHKHGFKK_02867 5.8e-104 yetJ S Belongs to the BI1 family
MHKHGFKK_02868 6e-232 wbbX GT2,GT4 M transferase activity, transferring glycosyl groups
MHKHGFKK_02869 1.2e-56 V ATPases associated with a variety of cellular activities
MHKHGFKK_02870 1.7e-70 S Protein of unknown function (DUF1430)
MHKHGFKK_02871 4.4e-17
MHKHGFKK_02872 1.8e-151 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHKHGFKK_02873 9.1e-103 sapB S MgtC SapB transporter
MHKHGFKK_02874 8.7e-161 S Protein of unknown function (DUF1646)
MHKHGFKK_02875 1.1e-218 EGP Major facilitator Superfamily
MHKHGFKK_02876 0.0 copA 3.6.3.54 P P-type ATPase
MHKHGFKK_02877 6.8e-30 P Copper resistance protein CopZ
MHKHGFKK_02878 7.8e-55 S protein conserved in bacteria
MHKHGFKK_02879 2.3e-69 lrpC K Transcriptional regulator
MHKHGFKK_02880 5.3e-74 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MHKHGFKK_02881 1e-223 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MHKHGFKK_02882 5.1e-27 yhjC S Protein of unknown function (DUF3311)
MHKHGFKK_02883 6.1e-266 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHKHGFKK_02885 8.2e-14 yhjQ C COG1145 Ferredoxin
MHKHGFKK_02887 7.7e-11 recN L Putative cell-wall binding lipoprotein
MHKHGFKK_02888 4.1e-175 nodB1 G deacetylase
MHKHGFKK_02893 1.6e-244 P Voltage gated chloride channel
MHKHGFKK_02894 1.9e-49 P Rhodanese domain protein
MHKHGFKK_02895 8.6e-38 yhjE S protein conserved in bacteria
MHKHGFKK_02896 2.4e-136 yokF 3.1.31.1 L RNA catabolic process
MHKHGFKK_02897 7.3e-71 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MHKHGFKK_02898 3e-306 araB 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MHKHGFKK_02899 6.5e-281 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MHKHGFKK_02900 3.5e-181 gguB G Belongs to the binding-protein-dependent transport system permease family
MHKHGFKK_02901 2.3e-284 araG 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MHKHGFKK_02902 1.3e-196 chvE G ABC transporter
MHKHGFKK_02903 1.8e-212 araR K transcriptional
MHKHGFKK_02904 1.3e-281 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MHKHGFKK_02905 1.8e-127 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MHKHGFKK_02906 6.1e-255 araP EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHKHGFKK_02907 6e-307 araB 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MHKHGFKK_02908 8.6e-215 araR K transcriptional
MHKHGFKK_02909 2.2e-261 NT chemotaxis protein
MHKHGFKK_02910 2.1e-128 plsB 2.3.1.15 I Acyl-transferase
MHKHGFKK_02911 1.4e-203 2.4.1.83 GT2 M Glycosyl transferase family 2
MHKHGFKK_02912 9.5e-133 IQ Enoyl-(Acyl carrier protein) reductase
MHKHGFKK_02913 6e-74 yuiD S protein conserved in bacteria
MHKHGFKK_02914 1.8e-220 solA 1.5.3.1 E FAD dependent oxidoreductase
MHKHGFKK_02915 7.6e-227 FOXRED 1.5.3.1 E FAD dependent oxidoreductase
MHKHGFKK_02916 2.6e-280 ycbD 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHKHGFKK_02917 6.2e-171 4.3.1.12 E ornithine cyclodeaminase
MHKHGFKK_02920 3.7e-182 yugO P COG1226 Kef-type K transport systems
MHKHGFKK_02921 2.3e-259 pgi 5.3.1.9 G Belongs to the GPI family
MHKHGFKK_02922 6.7e-34 yuzA S Domain of unknown function (DUF378)
MHKHGFKK_02923 4e-86 K Bacterial transcription activator, effector binding domain
MHKHGFKK_02924 1.2e-64 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MHKHGFKK_02925 5.9e-29 K Helix-turn-helix XRE-family like proteins
MHKHGFKK_02926 1.5e-194 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MHKHGFKK_02927 1.6e-165 S reductase
MHKHGFKK_02928 4.9e-159 dkgB S Aldo/keto reductase family
MHKHGFKK_02929 2.4e-239 S protein conserved in bacteria
MHKHGFKK_02931 2.1e-111 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHKHGFKK_02932 9.9e-67 kapB G Kinase associated protein B
MHKHGFKK_02933 2.1e-13 S double-stranded DNA endodeoxyribonuclease activity
MHKHGFKK_02934 3.5e-12 S transposase or invertase
MHKHGFKK_02935 1.6e-219 EGP Major facilitator Superfamily
MHKHGFKK_02938 0.0 pepF2 E COG1164 Oligoendopeptidase F
MHKHGFKK_02939 7e-34 ykuS S Belongs to the UPF0180 family
MHKHGFKK_02940 1e-20
MHKHGFKK_02941 0.0 6.2.1.1, 6.2.1.16 I AMP-dependent synthetase
MHKHGFKK_02942 4.6e-94 ywrA P COG2059 Chromate transport protein ChrA
MHKHGFKK_02943 1.3e-102 chrA P Chromate transporter
MHKHGFKK_02944 7.2e-83 ywrC K Transcriptional regulator
MHKHGFKK_02945 7.2e-231 EGP Uncharacterised MFS-type transporter YbfB
MHKHGFKK_02946 1.7e-309 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MHKHGFKK_02947 1.6e-227 3.5.1.4, 6.3.5.6, 6.3.5.7 J Belongs to the amidase family
MHKHGFKK_02948 1.3e-21 EGP Major facilitator Superfamily
MHKHGFKK_02949 2.5e-122 EGP Major facilitator Superfamily
MHKHGFKK_02951 3.8e-162 pocR K Sensory domain found in PocR
MHKHGFKK_02952 6.5e-229 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHKHGFKK_02953 1.1e-214 yxjG 2.1.1.14 E Methionine synthase
MHKHGFKK_02955 1.6e-45 esxA S Belongs to the WXG100 family
MHKHGFKK_02957 0.0 esaA S domain protein
MHKHGFKK_02958 1e-07 S WXG100 protein secretion system (Wss), protein EssA
MHKHGFKK_02959 1.4e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
MHKHGFKK_02960 1.7e-217 essB S WXG100 protein secretion system (Wss), protein YukC
MHKHGFKK_02961 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MHKHGFKK_02962 2.3e-26
MHKHGFKK_02963 1.6e-27 S Proteins of 100 residues with WXG
MHKHGFKK_02964 9.8e-81 S Domain of unknown function (DUF5081)
MHKHGFKK_02965 1.7e-30
MHKHGFKK_02966 1.4e-122 S domain, Protein
MHKHGFKK_02967 4e-66 S Uncharacterized protein conserved in bacteria (DUF2247)
MHKHGFKK_02968 2e-39 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MHKHGFKK_02969 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MHKHGFKK_02970 4.2e-10 S Domain of unknown function (DUF5082)
MHKHGFKK_02971 4.5e-43
MHKHGFKK_02972 1.8e-23 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHKHGFKK_02973 4e-240 L Transposase DDE domain group 1
MHKHGFKK_02974 6e-188 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHKHGFKK_02975 1.1e-70 cas4 3.1.12.1 L Domain of unknown function DUF83
MHKHGFKK_02976 0.0 cas3 L CRISPR-associated helicase, Cas3
MHKHGFKK_02977 3e-144 cas5h S CRISPR-associated protein Cas5
MHKHGFKK_02978 4.1e-178 L CRISPR-associated protein Cas7
MHKHGFKK_02979 0.0 csh
MHKHGFKK_02980 1.6e-126 cas6 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA)
MHKHGFKK_02981 0.0 snf 2.7.11.1 L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHKHGFKK_02982 3.6e-108 C Nitroreductase family
MHKHGFKK_02983 9.1e-89 1.8.5.2 S DoxX
MHKHGFKK_02984 7.8e-191 fni 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MHKHGFKK_02985 8.2e-117 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MHKHGFKK_02986 6e-35 yoeD G Helix-turn-helix domain
MHKHGFKK_02987 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MHKHGFKK_02988 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MHKHGFKK_02989 8.4e-134 fruR K Transcriptional regulator
MHKHGFKK_02990 1e-201 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
MHKHGFKK_02991 1.6e-94 D Hemerythrin HHE cation binding
MHKHGFKK_02992 1.1e-152 yidA S hydrolases of the HAD superfamily
MHKHGFKK_02993 3.5e-57 ygbA S Nitrous oxide-stimulated promoter
MHKHGFKK_02994 5.1e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MHKHGFKK_02995 3.5e-272 iolT EGP Major facilitator Superfamily
MHKHGFKK_02996 2.8e-204 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MHKHGFKK_02998 1.8e-72 ywnF S Family of unknown function (DUF5392)
MHKHGFKK_02999 2.4e-136 ywaC 2.7.6.5 S protein conserved in bacteria
MHKHGFKK_03000 6.1e-252 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHKHGFKK_03001 1.9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
MHKHGFKK_03002 1.4e-99 dhaL 2.7.1.121 S Dak2
MHKHGFKK_03003 4.5e-180 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
MHKHGFKK_03004 1.3e-174 pfoS S Phosphotransferase system, EIIC
MHKHGFKK_03006 1.3e-134 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MHKHGFKK_03007 6.6e-235 E COG1113 Gamma-aminobutyrate permease and related permeases
MHKHGFKK_03009 3.4e-150 ytnM S membrane transporter protein
MHKHGFKK_03014 1.6e-08
MHKHGFKK_03022 1e-92 ydcK S Belongs to the SprT family
MHKHGFKK_03023 0.0 yhgF K COG2183 Transcriptional accessory protein
MHKHGFKK_03024 7.3e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MHKHGFKK_03025 3.7e-137 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHKHGFKK_03026 2.5e-80 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MHKHGFKK_03027 1.8e-57 rsbV T Belongs to the anti-sigma-factor antagonist family
MHKHGFKK_03028 4.5e-194 rsbU 3.1.3.3 KT phosphatase
MHKHGFKK_03029 2e-70 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MHKHGFKK_03030 8.1e-55 rsbS T antagonist
MHKHGFKK_03031 2.6e-152 rsbR T Positive regulator of sigma-B
MHKHGFKK_03032 7.2e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MHKHGFKK_03033 2e-40 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MHKHGFKK_03034 1.7e-218 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHKHGFKK_03035 8.4e-190 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MHKHGFKK_03036 1.2e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHKHGFKK_03037 3.8e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MHKHGFKK_03038 1.7e-260 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHKHGFKK_03039 1.5e-61
MHKHGFKK_03040 3.2e-107 E Lysine exporter protein LysE YggA
MHKHGFKK_03041 2.7e-123 otsB2 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MHKHGFKK_03042 2.9e-176 yvdE K Transcriptional regulator
MHKHGFKK_03043 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MHKHGFKK_03044 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MHKHGFKK_03045 7e-242 mdxE G COG2182 Maltose-binding periplasmic proteins domains
MHKHGFKK_03046 7.2e-242 malC P COG1175 ABC-type sugar transport systems, permease components
MHKHGFKK_03047 1.5e-155 malD P transport
MHKHGFKK_03048 1.3e-143 malA S Protein of unknown function (DUF1189)
MHKHGFKK_03049 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MHKHGFKK_03050 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MHKHGFKK_03051 6.4e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHKHGFKK_03052 3.3e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MHKHGFKK_03053 2.1e-148
MHKHGFKK_03054 2.7e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MHKHGFKK_03055 7.8e-82 cueR K transcriptional
MHKHGFKK_03056 8.4e-249 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MHKHGFKK_03058 3.2e-300 ywqB S Zinc finger, swim domain protein
MHKHGFKK_03059 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHKHGFKK_03061 3.3e-71 ywpF S YwpF-like protein
MHKHGFKK_03062 5.7e-64 ssbB L Single-stranded DNA-binding protein
MHKHGFKK_03064 1.2e-73 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHKHGFKK_03065 1.7e-148 flhP N flagellar basal body
MHKHGFKK_03066 4.9e-145 flhO N flagellar basal body
MHKHGFKK_03067 1e-179 mbl D Rod shape-determining protein
MHKHGFKK_03069 1.3e-41 spoIIID K Stage III sporulation protein D
MHKHGFKK_03070 1.6e-127 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MHKHGFKK_03071 3.4e-183 spoIID D Stage II sporulation protein D
MHKHGFKK_03072 8.8e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHKHGFKK_03073 1.3e-134 ywmB S TATA-box binding
MHKHGFKK_03074 1.4e-34 ywzB S membrane
MHKHGFKK_03075 6.3e-59 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MHKHGFKK_03076 2.7e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHKHGFKK_03077 5e-151 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHKHGFKK_03078 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHKHGFKK_03079 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHKHGFKK_03080 1e-37 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHKHGFKK_03081 1.3e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHKHGFKK_03082 8.2e-131 atpB C it plays a direct role in the translocation of protons across the membrane
MHKHGFKK_03083 4.1e-57 atpI S ATP synthase I chain
MHKHGFKK_03084 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHKHGFKK_03085 2.4e-239 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHKHGFKK_03086 9.1e-101 ywlG S Belongs to the UPF0340 family
MHKHGFKK_03087 1.4e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MHKHGFKK_03089 3.8e-163 mcpA NT Chemotaxis
MHKHGFKK_03090 4.6e-79 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHKHGFKK_03091 8.3e-91 mntP P Probably functions as a manganese efflux pump
MHKHGFKK_03092 6.3e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHKHGFKK_03093 7.4e-122 spoIIR S stage II sporulation protein R
MHKHGFKK_03094 1.3e-162 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHKHGFKK_03095 6.6e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHKHGFKK_03096 1.4e-50 S Domain of unknown function (DUF1851)
MHKHGFKK_03097 3.8e-96 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MHKHGFKK_03098 2.2e-246 yicJ G MFS/sugar transport protein
MHKHGFKK_03099 3.3e-302 2.7.1.12, 2.7.1.17 G xylulose kinase
MHKHGFKK_03100 2.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKHGFKK_03101 1.9e-214 2.7.1.2 GK ROK family
MHKHGFKK_03102 2.7e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHKHGFKK_03103 1.6e-71 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHKHGFKK_03104 8.4e-36
MHKHGFKK_03106 7.4e-283 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHKHGFKK_03107 9.4e-219 yxjG 2.1.1.14 E Methionine synthase
MHKHGFKK_03108 1.6e-219 yhjX P Major facilitator superfamily
MHKHGFKK_03109 3.6e-137 ypdB T LytTr DNA-binding domain
MHKHGFKK_03110 0.0 ypdA 2.7.13.3 T Signal transduction histidine kinase
MHKHGFKK_03111 1.4e-197 ansA 3.5.1.1 EJ L-asparaginase
MHKHGFKK_03112 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MHKHGFKK_03113 7.4e-106 yhgD K Transcriptional regulator
MHKHGFKK_03114 1.8e-261 yhgE S YhgE Pip N-terminal domain protein
MHKHGFKK_03115 6.6e-248 S Protein of unknown function N-terminus (DUF3323)
MHKHGFKK_03116 0.0 D Putative exonuclease SbcCD, C subunit
MHKHGFKK_03117 1.4e-228 S Protein of unknown function (DUF2398)
MHKHGFKK_03119 4e-257 S Protein of unknown function (DUF2397)
MHKHGFKK_03120 1.8e-81
MHKHGFKK_03122 1.6e-161 NT chemotaxis protein
MHKHGFKK_03123 6.7e-156 yoaT S Protein of unknown function (DUF817)
MHKHGFKK_03124 1.2e-29 yozG K Transcriptional regulator
MHKHGFKK_03125 6.6e-76 yoaS S Protein of unknown function (DUF2975)
MHKHGFKK_03126 1.1e-54
MHKHGFKK_03127 5.6e-237 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHKHGFKK_03128 9.6e-75 yqgC S protein conserved in bacteria
MHKHGFKK_03129 1.2e-272 ydbT S Bacterial PH domain
MHKHGFKK_03130 2.1e-85 S Bacterial PH domain
MHKHGFKK_03131 4.3e-86 S AAA domain
MHKHGFKK_03132 1.2e-31 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
MHKHGFKK_03133 2.3e-268 proP EGP Transporter
MHKHGFKK_03134 1.1e-191 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHKHGFKK_03135 6.9e-50 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHKHGFKK_03136 2.7e-146 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHKHGFKK_03137 1.8e-120 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MHKHGFKK_03138 2.6e-183 2.3.1.180 I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
MHKHGFKK_03139 2.7e-58
MHKHGFKK_03141 2.5e-250 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MHKHGFKK_03142 1.1e-15 S Ribbon-helix-helix protein, copG family
MHKHGFKK_03143 7.1e-77 3.6.1.55 F Belongs to the Nudix hydrolase family
MHKHGFKK_03144 6.3e-49 F nucleoside 2-deoxyribosyltransferase
MHKHGFKK_03145 2.7e-116 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHKHGFKK_03146 1.1e-67 Q methyltransferase
MHKHGFKK_03147 2.4e-127 2.5.1.2 M transport
MHKHGFKK_03148 9.9e-247 cytX F Permease for cytosine/purines, uracil, thiamine, allantoin
MHKHGFKK_03149 9e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MHKHGFKK_03150 2.8e-137 IQ Enoyl-(Acyl carrier protein) reductase
MHKHGFKK_03151 6.4e-124 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHKHGFKK_03152 7.8e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MHKHGFKK_03153 4.1e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MHKHGFKK_03154 3.4e-123 yflK S protein conserved in bacteria
MHKHGFKK_03155 1.5e-47
MHKHGFKK_03156 2e-203 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHKHGFKK_03157 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHKHGFKK_03158 1.8e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHKHGFKK_03159 4.5e-112 ccpN K CBS domain
MHKHGFKK_03160 3.1e-144 recO L Involved in DNA repair and RecF pathway recombination
MHKHGFKK_03161 3e-08 S YqzL-like protein
MHKHGFKK_03162 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHKHGFKK_03163 3e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MHKHGFKK_03164 2.3e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHKHGFKK_03165 0.0 yqfF S membrane-associated HD superfamily hydrolase
MHKHGFKK_03166 5.2e-173 phoH T Phosphate starvation-inducible protein PhoH
MHKHGFKK_03167 7.3e-225 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MHKHGFKK_03168 4.2e-46 yqfC S sporulation protein YqfC
MHKHGFKK_03169 5.4e-72 yqeY S Yqey-like protein
MHKHGFKK_03170 9.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MHKHGFKK_03171 8.5e-47 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MHKHGFKK_03172 3.3e-156 yqeW P COG1283 Na phosphate symporter
MHKHGFKK_03173 5.5e-261 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MHKHGFKK_03174 1.6e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHKHGFKK_03175 1.7e-173 prmA J Methylates ribosomal protein L11
MHKHGFKK_03176 1.5e-206 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHKHGFKK_03177 2.5e-309 dnaK O Heat shock 70 kDa protein
MHKHGFKK_03178 1.9e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHKHGFKK_03179 3.2e-189 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHKHGFKK_03180 2.5e-219 hemN H Involved in the biosynthesis of porphyrin-containing compound
MHKHGFKK_03181 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHKHGFKK_03182 1.6e-224 spoIIP M stage II sporulation protein P
MHKHGFKK_03183 1.1e-198 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MHKHGFKK_03184 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
MHKHGFKK_03185 1.4e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
MHKHGFKK_03186 3.1e-07 S YqzM-like protein
MHKHGFKK_03187 0.0 comEC S Competence protein ComEC
MHKHGFKK_03188 3.6e-111 comEB 3.5.4.12 F COG2131 Deoxycytidylate deaminase
MHKHGFKK_03189 6.8e-85 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
MHKHGFKK_03190 9.3e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHKHGFKK_03191 8.5e-147 cmoA S Methyltransferase domain
MHKHGFKK_03192 2.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHKHGFKK_03193 1.6e-100 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MHKHGFKK_03194 1.9e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHKHGFKK_03195 8.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MHKHGFKK_03196 1.2e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHKHGFKK_03197 4.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MHKHGFKK_03198 2.2e-93 yqeG S hydrolase of the HAD superfamily
MHKHGFKK_03199 3e-259 glcF C Glycolate oxidase
MHKHGFKK_03200 1.6e-255 glcD 1.1.3.15 C Glycolate oxidase subunit
MHKHGFKK_03201 9.5e-195 ysfB KT regulator
MHKHGFKK_03202 2.2e-228 mco 1.16.3.3 Q multicopper oxidases
MHKHGFKK_03203 1.4e-72 hsp18 O Belongs to the small heat shock protein (HSP20) family
MHKHGFKK_03204 3.6e-19 S Short C-terminal domain
MHKHGFKK_03205 7.2e-88 CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MHKHGFKK_03206 1.9e-104 S TPM domain
MHKHGFKK_03207 2.1e-76 lemA S LemA family
MHKHGFKK_03208 2.5e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHKHGFKK_03209 1.4e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHKHGFKK_03210 1.6e-118 S VIT family
MHKHGFKK_03211 4.6e-155 czcD P COG1230 Co Zn Cd efflux system component
MHKHGFKK_03212 4.2e-15 sda S Sporulation inhibitor A
MHKHGFKK_03213 4.5e-97 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHKHGFKK_03214 2.1e-126 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHKHGFKK_03216 2.1e-293 ahpF O Alkyl hydroperoxide reductase
MHKHGFKK_03217 2.9e-107 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MHKHGFKK_03219 5e-10 S YrhC-like protein
MHKHGFKK_03220 2.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHKHGFKK_03221 1.2e-29 yrzA S Protein of unknown function (DUF2536)
MHKHGFKK_03222 5.5e-59 yrrS S Protein of unknown function (DUF1510)
MHKHGFKK_03223 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHKHGFKK_03224 2e-112 udk 2.7.1.48 F Cytidine monophosphokinase
MHKHGFKK_03225 1.1e-115 yrrM 2.1.1.104 S O-methyltransferase
MHKHGFKK_03226 1.3e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHKHGFKK_03227 1.5e-41 yrzB S Belongs to the UPF0473 family
MHKHGFKK_03228 8.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHKHGFKK_03229 5.8e-45 yrzL S Belongs to the UPF0297 family
MHKHGFKK_03230 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHKHGFKK_03231 8.2e-175 yrrI S AI-2E family transporter
MHKHGFKK_03233 1.8e-29 yrzR
MHKHGFKK_03234 1.1e-66 yndM S Protein of unknown function (DUF2512)
MHKHGFKK_03235 1.3e-57 K helix_turn_helix ASNC type
MHKHGFKK_03236 1.2e-176 pdh 1.4.1.20, 1.4.1.9 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
MHKHGFKK_03237 9.5e-168 bkdA1 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MHKHGFKK_03238 1.8e-160 pdhB 1.2.4.1 C Transketolase, C-terminal domain
MHKHGFKK_03239 6e-153 bkdB 1.8.1.4, 2.3.1.12, 2.3.1.168 C 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
MHKHGFKK_03240 2e-194 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
MHKHGFKK_03241 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MHKHGFKK_03242 8.2e-125 S COG0457 FOG TPR repeat
MHKHGFKK_03243 1.3e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHKHGFKK_03244 1.5e-208 iscS 2.8.1.7 E Cysteine desulfurase
MHKHGFKK_03245 2.3e-72 cymR K Transcriptional regulator
MHKHGFKK_03246 4.8e-185 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MHKHGFKK_03247 7.4e-138 ytlC P ABC transporter
MHKHGFKK_03248 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHKHGFKK_03249 2.4e-83 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MHKHGFKK_03250 7.4e-39
MHKHGFKK_03251 6.6e-78 dps P Belongs to the Dps family
MHKHGFKK_03252 1.3e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MHKHGFKK_03254 6.3e-165 adcA P Belongs to the bacterial solute-binding protein 9 family
MHKHGFKK_03255 1.6e-23 S Domain of Unknown Function (DUF1540)
MHKHGFKK_03256 1e-204 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MHKHGFKK_03257 1.9e-275 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MHKHGFKK_03258 7.1e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MHKHGFKK_03259 3.7e-148 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MHKHGFKK_03260 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MHKHGFKK_03261 4.6e-252 menF 5.4.4.2 HQ Isochorismate synthase
MHKHGFKK_03262 3.8e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MHKHGFKK_03278 5.1e-08
MHKHGFKK_03279 1.6e-08
MHKHGFKK_03283 2.7e-182 yaaC S YaaC-like Protein
MHKHGFKK_03284 1.5e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MHKHGFKK_03285 3.2e-250 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MHKHGFKK_03286 1.6e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MHKHGFKK_03287 4.4e-103 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MHKHGFKK_03288 9.2e-210 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHKHGFKK_03289 2.9e-09
MHKHGFKK_03290 1.3e-125 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MHKHGFKK_03291 5.4e-118 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MHKHGFKK_03292 2.6e-252 yaaH M Glycoside Hydrolase Family
MHKHGFKK_03294 1e-87 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHKHGFKK_03295 4.7e-310 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHKHGFKK_03296 3.9e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHKHGFKK_03297 1.5e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHKHGFKK_03298 6.9e-09 S Protein of unknown function (DUF2508)
MHKHGFKK_03299 5.7e-37 bofA S Sigma-K factor-processing regulatory protein BofA
MHKHGFKK_03300 1.5e-190 yuxJ EGP Major facilitator Superfamily
MHKHGFKK_03301 9.4e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
MHKHGFKK_03302 5.3e-62 yuzC
MHKHGFKK_03304 4.3e-187 E Spore germination protein
MHKHGFKK_03305 1.9e-225 gerKC S spore germination
MHKHGFKK_03306 3e-301 gerKA EG Spore germination protein
MHKHGFKK_03308 1.3e-292 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MHKHGFKK_03309 2.4e-107 yuiC S protein conserved in bacteria
MHKHGFKK_03310 9.5e-47 yuiB S Putative membrane protein
MHKHGFKK_03311 1.5e-230 yumB 1.6.99.3 C NADH dehydrogenase
MHKHGFKK_03312 2.4e-181 yumC 1.18.1.2, 1.19.1.1 C reductase
MHKHGFKK_03313 3.1e-56 S response to antibiotic
MHKHGFKK_03314 5.3e-78 tcaA S response to antibiotic
MHKHGFKK_03315 6.2e-74 ycdA S Domain of unknown function (DUF4352)
MHKHGFKK_03316 2.2e-63 erpA S Belongs to the HesB IscA family
MHKHGFKK_03317 5.6e-61 yuzD S protein conserved in bacteria
MHKHGFKK_03318 5.1e-37 nifU O COG0694 Thioredoxin-like proteins and domains
MHKHGFKK_03319 3.4e-199 yutH S Spore coat protein
MHKHGFKK_03320 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MHKHGFKK_03321 3.9e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHKHGFKK_03322 5.7e-74 yutE S Protein of unknown function DUF86
MHKHGFKK_03323 3.4e-48 yutD S protein conserved in bacteria
MHKHGFKK_03324 5.5e-172 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MHKHGFKK_03325 2.6e-196 lytH M Peptidase, M23
MHKHGFKK_03326 5e-128 yunB S Sporulation protein YunB (Spo_YunB)
MHKHGFKK_03327 8.2e-48 yunC S Domain of unknown function (DUF1805)
MHKHGFKK_03328 5.1e-286 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MHKHGFKK_03329 2.9e-273 sufB O FeS cluster assembly
MHKHGFKK_03330 9.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MHKHGFKK_03331 1.5e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHKHGFKK_03332 1.4e-242 sufD O assembly protein SufD
MHKHGFKK_03333 2.7e-143 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MHKHGFKK_03335 3.6e-51 traF CO Thioredoxin
MHKHGFKK_03336 7.1e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MHKHGFKK_03337 1.3e-63 arsC 1.20.4.1 P Belongs to the ArsC family
MHKHGFKK_03338 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MHKHGFKK_03339 6.1e-216 fadA 2.3.1.16 I Belongs to the thiolase family
MHKHGFKK_03340 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MHKHGFKK_03341 2.6e-14 S YuzL-like protein
MHKHGFKK_03342 7.4e-42
MHKHGFKK_03343 6.3e-35 yusN M Coat F domain
MHKHGFKK_03345 2.4e-204 rodA D Belongs to the SEDS family
MHKHGFKK_03346 1.9e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MHKHGFKK_03347 2.7e-282 cls2 I PLD-like domain
MHKHGFKK_03349 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MHKHGFKK_03351 8.3e-193 M1-600 T Putative diguanylate phosphodiesterase
MHKHGFKK_03352 1.1e-299 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MHKHGFKK_03353 4.3e-106 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MHKHGFKK_03354 5.7e-143 pgdA 3.5.1.104, 3.5.1.41 G Polysaccharide deacetylase
MHKHGFKK_03355 2.6e-244 ugtP 2.4.1.315 GT28 M Monogalactosyldiacylglycerol (MGDG) synthase
MHKHGFKK_03356 4.5e-131
MHKHGFKK_03357 1.9e-86 S Putative zinc-finger
MHKHGFKK_03358 3e-93 K Belongs to the sigma-70 factor family. ECF subfamily
MHKHGFKK_03359 6e-224 ykoN 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MHKHGFKK_03360 0.0 M Dolichyl-phosphate-mannose-protein mannosyltransferase
MHKHGFKK_03361 4.2e-259 NU cell adhesion
MHKHGFKK_03362 5.2e-184 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MHKHGFKK_03363 4e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MHKHGFKK_03364 1.6e-165 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MHKHGFKK_03365 2.8e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKHGFKK_03366 1.3e-260 yjmB G MFS/sugar transport protein
MHKHGFKK_03367 4.6e-279 uxaC 5.3.1.12 G glucuronate isomerase
MHKHGFKK_03368 3.4e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MHKHGFKK_03369 1.9e-272 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MHKHGFKK_03370 1.1e-189 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
MHKHGFKK_03371 3e-119 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MHKHGFKK_03372 2.8e-137 K helix_turn_helix isocitrate lyase regulation

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)