ORF_ID e_value Gene_name EC_number CAZy COGs Description
ICOLMEJK_00001 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
ICOLMEJK_00002 1.1e-86 ykhA 3.1.2.20 I Thioesterase superfamily
ICOLMEJK_00003 5.5e-161 aatB ET PFAM extracellular solute-binding protein, family 3
ICOLMEJK_00004 4.1e-212 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ICOLMEJK_00005 8.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ICOLMEJK_00006 5.2e-158 lutA C Cysteine-rich domain
ICOLMEJK_00007 2.4e-286 lutB C 4Fe-4S dicluster domain
ICOLMEJK_00008 3.6e-134 yrjD S LUD domain
ICOLMEJK_00009 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ICOLMEJK_00010 1.2e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
ICOLMEJK_00011 9.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ICOLMEJK_00012 3.9e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ICOLMEJK_00013 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
ICOLMEJK_00014 3.5e-31 KT PspC domain protein
ICOLMEJK_00015 4.3e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ICOLMEJK_00016 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ICOLMEJK_00017 6.8e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ICOLMEJK_00018 7.2e-113 comFC S Competence protein
ICOLMEJK_00019 2.2e-254 comFA L Helicase C-terminal domain protein
ICOLMEJK_00020 2e-109 yvyE 3.4.13.9 S YigZ family
ICOLMEJK_00021 8.1e-36 EGP Major facilitator Superfamily
ICOLMEJK_00022 4.2e-182 EGP Major facilitator Superfamily
ICOLMEJK_00023 1.8e-66 rmaI K Transcriptional regulator
ICOLMEJK_00024 1.6e-39
ICOLMEJK_00025 0.0 ydaO E amino acid
ICOLMEJK_00026 2.4e-303 ybeC E amino acid
ICOLMEJK_00027 2.4e-81 S Aminoacyl-tRNA editing domain
ICOLMEJK_00028 1.4e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ICOLMEJK_00029 3.3e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ICOLMEJK_00030 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ICOLMEJK_00031 7e-310 uup S ABC transporter, ATP-binding protein
ICOLMEJK_00032 1.5e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICOLMEJK_00033 1.2e-224 mtnE 2.6.1.83 E Aminotransferase
ICOLMEJK_00034 3.1e-139 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
ICOLMEJK_00035 4.2e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICOLMEJK_00036 3.8e-216 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ICOLMEJK_00037 4e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICOLMEJK_00038 8.9e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ICOLMEJK_00039 4.7e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
ICOLMEJK_00040 2.6e-124 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
ICOLMEJK_00041 5.7e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
ICOLMEJK_00042 1.9e-170 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ICOLMEJK_00043 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ICOLMEJK_00044 9.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ICOLMEJK_00045 3.2e-133 fat 3.1.2.21 I Acyl-ACP thioesterase
ICOLMEJK_00046 1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ICOLMEJK_00047 5.9e-58 yabA L Involved in initiation control of chromosome replication
ICOLMEJK_00048 5.5e-181 holB 2.7.7.7 L DNA polymerase III
ICOLMEJK_00049 7.6e-52 yaaQ S Cyclic-di-AMP receptor
ICOLMEJK_00050 9.6e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICOLMEJK_00051 9.7e-39 S Protein of unknown function (DUF2508)
ICOLMEJK_00052 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ICOLMEJK_00053 7.8e-46 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ICOLMEJK_00054 6.4e-281 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICOLMEJK_00055 3.8e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ICOLMEJK_00056 3.4e-35 nrdH O Glutaredoxin
ICOLMEJK_00057 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICOLMEJK_00058 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICOLMEJK_00059 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
ICOLMEJK_00060 5.4e-133 S Putative adhesin
ICOLMEJK_00061 2.5e-80 XK27_06920 S Protein of unknown function (DUF1700)
ICOLMEJK_00062 2.4e-56 K transcriptional regulator PadR family
ICOLMEJK_00063 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ICOLMEJK_00065 7.7e-48
ICOLMEJK_00066 1.8e-31
ICOLMEJK_00067 4.1e-116 S CAAX protease self-immunity
ICOLMEJK_00068 5.6e-43
ICOLMEJK_00070 3.7e-41 L Belongs to the 'phage' integrase family
ICOLMEJK_00071 2.3e-47 L Belongs to the 'phage' integrase family
ICOLMEJK_00073 6e-132
ICOLMEJK_00075 6.6e-15
ICOLMEJK_00076 3.3e-18
ICOLMEJK_00077 2.7e-20 E Zn peptidase
ICOLMEJK_00078 1.9e-47 ps115 K Helix-turn-helix XRE-family like proteins
ICOLMEJK_00079 1.5e-13
ICOLMEJK_00080 7.8e-68 S DNA binding
ICOLMEJK_00081 9.7e-13 S Domain of unknown function (DUF771)
ICOLMEJK_00084 6.7e-13 S Domain of unknown function (DUF1508)
ICOLMEJK_00087 7.1e-63 S Bacteriophage Mu Gam like protein
ICOLMEJK_00088 1.4e-116 S AAA domain
ICOLMEJK_00089 1.5e-42 S Protein of unknown function (DUF669)
ICOLMEJK_00090 1.7e-64 S Putative HNHc nuclease
ICOLMEJK_00091 8.5e-24 L Psort location Cytoplasmic, score
ICOLMEJK_00092 9.2e-57 dnaC 3.4.21.53 L IstB-like ATP binding protein
ICOLMEJK_00095 3.2e-52 S Protein of unknown function (DUF1064)
ICOLMEJK_00096 1.1e-52 S ORF6C domain
ICOLMEJK_00100 9.7e-33
ICOLMEJK_00102 1.6e-56 S Predicted membrane protein (DUF2335)
ICOLMEJK_00104 3.4e-59 S HicB_like antitoxin of bacterial toxin-antitoxin system
ICOLMEJK_00105 7.9e-22
ICOLMEJK_00106 1.6e-254 S Phage terminase, large subunit
ICOLMEJK_00107 1.9e-300 S Phage portal protein, SPP1 Gp6-like
ICOLMEJK_00108 3e-173 S Phage Mu protein F like protein
ICOLMEJK_00109 2e-78 S Domain of unknown function (DUF4355)
ICOLMEJK_00110 7.3e-200 gpG
ICOLMEJK_00111 1.5e-59 S Phage gp6-like head-tail connector protein
ICOLMEJK_00112 2.5e-52
ICOLMEJK_00113 2e-84
ICOLMEJK_00114 1.3e-67
ICOLMEJK_00115 5.3e-105
ICOLMEJK_00116 1.9e-79 S Phage tail assembly chaperone protein, TAC
ICOLMEJK_00117 1e-195 D NLP P60 protein
ICOLMEJK_00118 7e-98 S Phage tail protein
ICOLMEJK_00119 1.5e-191 S Peptidase family M23
ICOLMEJK_00121 4e-41 S Calcineurin-like phosphoesterase
ICOLMEJK_00122 6.4e-13 N Bacterial Ig-like domain 2
ICOLMEJK_00128 9.6e-32 feoA P FeoA domain
ICOLMEJK_00129 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
ICOLMEJK_00130 1.7e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
ICOLMEJK_00131 1.6e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ICOLMEJK_00132 1.6e-64 ydiI Q Thioesterase superfamily
ICOLMEJK_00133 9.2e-203 nrnB S DHHA1 domain
ICOLMEJK_00134 1.1e-49
ICOLMEJK_00135 1.4e-29 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ICOLMEJK_00136 8.7e-19 S Domain of unknown function (DUF4767)
ICOLMEJK_00137 3.6e-54
ICOLMEJK_00138 1.1e-116 yrkL S Flavodoxin-like fold
ICOLMEJK_00141 1.7e-201 xerS L Belongs to the 'phage' integrase family
ICOLMEJK_00142 2.7e-206 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
ICOLMEJK_00143 3.6e-157 rssA S Phospholipase, patatin family
ICOLMEJK_00144 1.6e-117 L Integrase
ICOLMEJK_00148 1e-225 yhdG E C-terminus of AA_permease
ICOLMEJK_00149 3e-20 uspA T Universal stress protein family
ICOLMEJK_00150 2.8e-37
ICOLMEJK_00151 2.9e-265 S Putative peptidoglycan binding domain
ICOLMEJK_00153 1.5e-11 2.7.13.3 T GHKL domain
ICOLMEJK_00154 9.9e-117 2.7.13.3 T GHKL domain
ICOLMEJK_00155 8.3e-104 K LytTr DNA-binding domain
ICOLMEJK_00165 1.4e-108 L Belongs to the 'phage' integrase family
ICOLMEJK_00167 3.3e-09
ICOLMEJK_00168 2e-17
ICOLMEJK_00169 8.8e-45
ICOLMEJK_00170 1.2e-79 E IrrE N-terminal-like domain
ICOLMEJK_00172 3.8e-159 metQ_4 P Belongs to the nlpA lipoprotein family
ICOLMEJK_00173 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ICOLMEJK_00174 2.7e-123 O Zinc-dependent metalloprotease
ICOLMEJK_00175 8.1e-111 S Membrane
ICOLMEJK_00176 2.5e-95 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
ICOLMEJK_00177 1.7e-44 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
ICOLMEJK_00178 4.1e-29 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
ICOLMEJK_00179 2.1e-180 K Transcriptional regulator, LacI family
ICOLMEJK_00180 1.6e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
ICOLMEJK_00181 3.6e-94
ICOLMEJK_00182 2.1e-25
ICOLMEJK_00183 1.1e-62 asp S Asp23 family, cell envelope-related function
ICOLMEJK_00184 3.2e-86 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
ICOLMEJK_00186 1.6e-217 htrA 3.4.21.107 O serine protease
ICOLMEJK_00187 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
ICOLMEJK_00188 2.5e-57 ABC-SBP S ABC transporter
ICOLMEJK_00189 6.3e-73 ABC-SBP S ABC transporter
ICOLMEJK_00190 8e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ICOLMEJK_00192 1.4e-31 L Transposase DDE domain group 1
ICOLMEJK_00193 7.2e-103 L Transposase DDE domain group 1
ICOLMEJK_00194 9e-23 1.1.98.6, 3.6.3.14, 3.6.3.15, 4.1.1.35 L Participates in initiation and elongation during chromosome replication
ICOLMEJK_00195 5.6e-08 gp17a S Terminase-like family
ICOLMEJK_00196 3.9e-14
ICOLMEJK_00200 1.2e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
ICOLMEJK_00201 2.5e-46 gcvH E glycine cleavage
ICOLMEJK_00202 2.4e-220 rodA D Belongs to the SEDS family
ICOLMEJK_00203 1.1e-30 S Protein of unknown function (DUF2969)
ICOLMEJK_00204 4.4e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
ICOLMEJK_00205 5.5e-178 mbl D Cell shape determining protein MreB Mrl
ICOLMEJK_00206 8e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICOLMEJK_00207 1.3e-33 ywzB S Protein of unknown function (DUF1146)
ICOLMEJK_00208 2e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
ICOLMEJK_00209 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ICOLMEJK_00210 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ICOLMEJK_00211 6.8e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ICOLMEJK_00212 4.3e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICOLMEJK_00213 1.4e-55 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ICOLMEJK_00214 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICOLMEJK_00215 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
ICOLMEJK_00216 2.5e-231 pyrP F Permease
ICOLMEJK_00217 6.3e-129 yibF S overlaps another CDS with the same product name
ICOLMEJK_00218 6.6e-188 yibE S overlaps another CDS with the same product name
ICOLMEJK_00219 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICOLMEJK_00220 4.3e-115 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ICOLMEJK_00221 6e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICOLMEJK_00222 1.5e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ICOLMEJK_00223 1.5e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ICOLMEJK_00224 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ICOLMEJK_00225 6e-108 tdk 2.7.1.21 F thymidine kinase
ICOLMEJK_00226 2e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
ICOLMEJK_00227 1.2e-134 cobQ S CobB/CobQ-like glutamine amidotransferase domain
ICOLMEJK_00228 6.1e-223 arcD U Amino acid permease
ICOLMEJK_00229 2.2e-260 E Arginine ornithine antiporter
ICOLMEJK_00230 8e-79 argR K Regulates arginine biosynthesis genes
ICOLMEJK_00231 4.5e-238 arcA 3.5.3.6 E Arginine
ICOLMEJK_00232 3.7e-177 ampC V Beta-lactamase
ICOLMEJK_00233 6.6e-33
ICOLMEJK_00234 4e-80 M domain protein
ICOLMEJK_00235 0.0 M domain protein
ICOLMEJK_00236 6.4e-90
ICOLMEJK_00238 1.5e-29 yjcE P Sodium proton antiporter
ICOLMEJK_00239 3.6e-57
ICOLMEJK_00241 5.3e-86
ICOLMEJK_00242 1.4e-264 npr 1.11.1.1 C NADH oxidase
ICOLMEJK_00243 4.1e-68 S pyridoxamine 5-phosphate
ICOLMEJK_00244 1.3e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
ICOLMEJK_00246 7.3e-183 pipD E Dipeptidase
ICOLMEJK_00247 7.5e-202 coiA 3.6.4.12 S Competence protein
ICOLMEJK_00248 1.2e-120 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
ICOLMEJK_00249 1.2e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ICOLMEJK_00250 2.3e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
ICOLMEJK_00251 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICOLMEJK_00252 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ICOLMEJK_00253 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ICOLMEJK_00254 4.1e-116 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
ICOLMEJK_00255 4.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
ICOLMEJK_00256 4.4e-74 rplI J Binds to the 23S rRNA
ICOLMEJK_00257 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
ICOLMEJK_00258 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICOLMEJK_00259 4.3e-173
ICOLMEJK_00260 2.2e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ICOLMEJK_00261 1.2e-112 yjbH Q Thioredoxin
ICOLMEJK_00262 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
ICOLMEJK_00263 7.3e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ICOLMEJK_00264 9.2e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
ICOLMEJK_00265 0.0 pacL 3.6.3.8 P P-type ATPase
ICOLMEJK_00266 1.1e-74 pacL 3.6.3.8 P P-type ATPase
ICOLMEJK_00267 2.6e-85 dps P Belongs to the Dps family
ICOLMEJK_00268 2.8e-178 S Phosphotransferase system, EIIC
ICOLMEJK_00269 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICOLMEJK_00270 2.2e-168
ICOLMEJK_00271 7.7e-183 galR K Periplasmic binding protein-like domain
ICOLMEJK_00272 0.0 rafA 3.2.1.22 G alpha-galactosidase
ICOLMEJK_00273 3.4e-206 yttB EGP Major facilitator Superfamily
ICOLMEJK_00274 8.5e-59
ICOLMEJK_00275 1.6e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
ICOLMEJK_00276 1.2e-97 K DNA-binding helix-turn-helix protein
ICOLMEJK_00277 5.8e-177 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
ICOLMEJK_00278 1.3e-230 mntH P H( )-stimulated, divalent metal cation uptake system
ICOLMEJK_00279 8.1e-144 L PFAM Integrase catalytic region
ICOLMEJK_00280 7.3e-84 L Helix-turn-helix domain
ICOLMEJK_00281 2.1e-78 Q Methyltransferase
ICOLMEJK_00282 3.4e-115 ktrA P domain protein
ICOLMEJK_00283 5e-100 ktrB P Potassium uptake protein
ICOLMEJK_00284 4.5e-60 ktrB P Potassium uptake protein
ICOLMEJK_00285 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
ICOLMEJK_00286 6.9e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
ICOLMEJK_00287 8.8e-212 G Glycosyl hydrolases family 8
ICOLMEJK_00288 2.9e-235 ydaM M Glycosyl transferase
ICOLMEJK_00289 1.4e-56
ICOLMEJK_00290 1.6e-123 phoU P Plays a role in the regulation of phosphate uptake
ICOLMEJK_00291 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ICOLMEJK_00292 2.2e-154 pstA P Phosphate transport system permease protein PstA
ICOLMEJK_00293 7.3e-153 pstC P probably responsible for the translocation of the substrate across the membrane
ICOLMEJK_00294 2.5e-158 pstS P Phosphate
ICOLMEJK_00295 2.5e-74 K Transcriptional regulatory protein, C-terminal domain protein
ICOLMEJK_00296 4.7e-134 cbiO P ABC transporter
ICOLMEJK_00297 3.8e-135 P Cobalt transport protein
ICOLMEJK_00298 5.7e-178 nikMN P PDGLE domain
ICOLMEJK_00299 1.3e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
ICOLMEJK_00300 3.9e-113 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ICOLMEJK_00301 1.7e-125 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
ICOLMEJK_00302 8.6e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ICOLMEJK_00303 0.0 ureC 3.5.1.5 E Amidohydrolase family
ICOLMEJK_00304 1e-60 ureB 3.5.1.5 E Urease beta subunit
ICOLMEJK_00305 1e-41 ureA 3.5.1.5 E Urease, gamma subunit
ICOLMEJK_00306 1.6e-96 ureI S AmiS/UreI family transporter
ICOLMEJK_00307 1.8e-38 P ammonium transporter
ICOLMEJK_00308 1.4e-122 P ammonium transporter
ICOLMEJK_00309 1.6e-31 P ammonium transporter
ICOLMEJK_00311 1.1e-186
ICOLMEJK_00312 9.8e-97 2.3.1.128 K acetyltransferase
ICOLMEJK_00313 4e-83 manA 5.3.1.8 G mannose-6-phosphate isomerase
ICOLMEJK_00314 5.7e-158 K LysR substrate binding domain
ICOLMEJK_00315 1.5e-203 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
ICOLMEJK_00316 2.5e-64 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICOLMEJK_00317 3.5e-33 cinA 3.5.1.42 S Competence-damaged protein
ICOLMEJK_00318 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
ICOLMEJK_00320 2.1e-70 repA S Replication initiator protein A
ICOLMEJK_00321 3.4e-109 nanH 4.1.3.3, 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICOLMEJK_00322 7.8e-260 gor 1.8.1.7 C Glutathione reductase
ICOLMEJK_00325 1.6e-55 S Iron-sulphur cluster biosynthesis
ICOLMEJK_00326 5.2e-106 I Carboxylesterase family
ICOLMEJK_00327 9.5e-92 L Helix-turn-helix domain
ICOLMEJK_00328 8e-79
ICOLMEJK_00329 2.5e-120 M Lysin motif
ICOLMEJK_00330 3.7e-197 EGP Major facilitator Superfamily
ICOLMEJK_00332 3.6e-73 K helix_turn_helix multiple antibiotic resistance protein
ICOLMEJK_00333 8.9e-309 lmrA 3.6.3.44 V ABC transporter
ICOLMEJK_00334 3.5e-160
ICOLMEJK_00335 1e-72 K Transcriptional regulator
ICOLMEJK_00336 1.2e-188 D Alpha beta
ICOLMEJK_00337 4.9e-52 ypaA S Protein of unknown function (DUF1304)
ICOLMEJK_00338 4.5e-46 yhcA V ABC transporter, ATP-binding protein
ICOLMEJK_00339 3.3e-273 yhcA V ABC transporter, ATP-binding protein
ICOLMEJK_00340 1.6e-35
ICOLMEJK_00341 9.1e-50 czrA K Transcriptional regulator, ArsR family
ICOLMEJK_00342 7.2e-153 glcU U sugar transport
ICOLMEJK_00343 3.1e-114 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
ICOLMEJK_00344 2e-36 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
ICOLMEJK_00345 3.8e-16
ICOLMEJK_00346 1.9e-46 3.2.1.4 GH5,GH9 M domain protein
ICOLMEJK_00347 2.5e-225 L Transposase
ICOLMEJK_00348 4.3e-29 cspA K Cold shock protein
ICOLMEJK_00349 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ICOLMEJK_00350 7.6e-195 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ICOLMEJK_00351 0.0 dnaK O Heat shock 70 kDa protein
ICOLMEJK_00352 3.9e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ICOLMEJK_00353 5.9e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ICOLMEJK_00354 5.8e-64
ICOLMEJK_00355 5e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
ICOLMEJK_00356 2e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ICOLMEJK_00357 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ICOLMEJK_00358 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ICOLMEJK_00359 1.3e-48 ylxQ J ribosomal protein
ICOLMEJK_00360 1e-44 ylxR K Protein of unknown function (DUF448)
ICOLMEJK_00361 1.8e-215 nusA K Participates in both transcription termination and antitermination
ICOLMEJK_00362 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
ICOLMEJK_00363 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICOLMEJK_00364 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ICOLMEJK_00365 8.3e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
ICOLMEJK_00366 3.4e-138 cdsA 2.7.7.41 I Belongs to the CDS family
ICOLMEJK_00367 6e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICOLMEJK_00368 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ICOLMEJK_00369 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
ICOLMEJK_00370 2.1e-152 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ICOLMEJK_00371 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
ICOLMEJK_00372 8.6e-179 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICOLMEJK_00373 1.6e-48 yazA L GIY-YIG catalytic domain protein
ICOLMEJK_00374 3.5e-140 yabB 2.1.1.223 L Methyltransferase small domain
ICOLMEJK_00375 2.3e-116 plsC 2.3.1.51 I Acyltransferase
ICOLMEJK_00376 4.8e-29 yneF S Uncharacterised protein family (UPF0154)
ICOLMEJK_00377 1.3e-35 ynzC S UPF0291 protein
ICOLMEJK_00378 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ICOLMEJK_00379 2.9e-210 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
ICOLMEJK_00380 7.9e-128 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICOLMEJK_00382 0.0 uvrA2 L ABC transporter
ICOLMEJK_00383 3.3e-22 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
ICOLMEJK_00384 1.9e-29 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
ICOLMEJK_00385 8.8e-164 S reductase
ICOLMEJK_00386 2.2e-164 L PFAM Integrase, catalytic core
ICOLMEJK_00387 3.8e-83 L Bacterial dnaA protein
ICOLMEJK_00388 1.4e-15 S PFAM Archaeal ATPase
ICOLMEJK_00389 2.5e-176 iolT EGP Major facilitator Superfamily
ICOLMEJK_00391 7e-209 yxjG_1 E methionine synthase, vitamin-B12 independent
ICOLMEJK_00392 7.8e-41 S Cytochrome B5
ICOLMEJK_00393 1.5e-277 O Arylsulfotransferase (ASST)
ICOLMEJK_00394 4e-213 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ICOLMEJK_00395 6.1e-168 murB 1.3.1.98 M Cell wall formation
ICOLMEJK_00396 1.7e-101 dnaQ 2.7.7.7 L DNA polymerase III
ICOLMEJK_00397 8.9e-77 S PAS domain
ICOLMEJK_00398 2.4e-77 K LytTr DNA-binding domain
ICOLMEJK_00399 1e-67 S Protein of unknown function (DUF3021)
ICOLMEJK_00400 8e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
ICOLMEJK_00401 8.5e-173 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
ICOLMEJK_00402 1.4e-207 rny S Endoribonuclease that initiates mRNA decay
ICOLMEJK_00403 2.9e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICOLMEJK_00404 6.9e-226 cinA 3.5.1.42 S Belongs to the CinA family
ICOLMEJK_00405 3.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICOLMEJK_00406 2.3e-142 ymfM S Helix-turn-helix domain
ICOLMEJK_00407 3e-248 ymfH S Peptidase M16
ICOLMEJK_00408 1.1e-228 ymfF S Peptidase M16 inactive domain protein
ICOLMEJK_00409 1e-159 aatB ET ABC transporter substrate-binding protein
ICOLMEJK_00410 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICOLMEJK_00411 1.2e-101 glnP P ABC transporter permease
ICOLMEJK_00412 8.7e-93 mreD M rod shape-determining protein MreD
ICOLMEJK_00413 3.8e-151 mreC M Involved in formation and maintenance of cell shape
ICOLMEJK_00414 5.1e-179 mreB D cell shape determining protein MreB
ICOLMEJK_00415 1.5e-120 radC L DNA repair protein
ICOLMEJK_00416 4.7e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ICOLMEJK_00417 3.8e-229 ndh 1.6.99.3 C NADH dehydrogenase
ICOLMEJK_00418 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ICOLMEJK_00419 2e-308 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
ICOLMEJK_00420 2e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
ICOLMEJK_00421 1.2e-271 cydA 1.10.3.14 C ubiquinol oxidase
ICOLMEJK_00422 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ICOLMEJK_00423 5.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICOLMEJK_00424 7.3e-214 iscS2 2.8.1.7 E Aminotransferase class V
ICOLMEJK_00425 6.5e-251 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ICOLMEJK_00426 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ICOLMEJK_00427 2.5e-21 S NADPH-dependent FMN reductase
ICOLMEJK_00428 3.1e-50 S NADPH-dependent FMN reductase
ICOLMEJK_00429 2.4e-167 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ICOLMEJK_00430 1.3e-11 S Transglycosylase associated protein
ICOLMEJK_00431 4e-69 S Asp23 family, cell envelope-related function
ICOLMEJK_00432 4.7e-22 S Small integral membrane protein (DUF2273)
ICOLMEJK_00433 1.8e-93
ICOLMEJK_00453 1.7e-246 yifK E Amino acid permease
ICOLMEJK_00454 2.3e-259 S Uncharacterised protein family (UPF0236)
ICOLMEJK_00455 1.4e-151 L PFAM Integrase catalytic region
ICOLMEJK_00456 1.1e-86 dps P Ferritin-like domain
ICOLMEJK_00457 2e-123 yciB M ErfK YbiS YcfS YnhG
ICOLMEJK_00459 7.2e-101
ICOLMEJK_00460 2.1e-112 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ICOLMEJK_00461 7.6e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ICOLMEJK_00462 6.8e-124 S Alpha beta hydrolase
ICOLMEJK_00463 1.9e-206 gldA 1.1.1.6 C dehydrogenase
ICOLMEJK_00464 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ICOLMEJK_00465 3.8e-41
ICOLMEJK_00466 1.9e-126 pgm3 3.1.3.73 G phosphoglycerate mutase family
ICOLMEJK_00467 1.4e-284 S C4-dicarboxylate anaerobic carrier
ICOLMEJK_00468 8.5e-249 nhaC C Na H antiporter NhaC
ICOLMEJK_00469 1.6e-241 pbuX F xanthine permease
ICOLMEJK_00470 2.5e-155 pipD E Dipeptidase
ICOLMEJK_00471 2e-97 pipD E Dipeptidase
ICOLMEJK_00472 6.5e-165 corA P CorA-like Mg2+ transporter protein
ICOLMEJK_00473 9.7e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ICOLMEJK_00474 3e-131 terC P membrane
ICOLMEJK_00475 2.7e-54 trxA O Belongs to the thioredoxin family
ICOLMEJK_00476 2.7e-236 mepA V MATE efflux family protein
ICOLMEJK_00477 6.8e-56 K Transcriptional regulator, ArsR family
ICOLMEJK_00478 2.9e-91 P Cadmium resistance transporter
ICOLMEJK_00479 3.2e-133 XK27_08845 S ABC transporter, ATP-binding protein
ICOLMEJK_00480 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
ICOLMEJK_00481 2.4e-181 ABC-SBP S ABC transporter
ICOLMEJK_00482 1.3e-73 M PFAM NLP P60 protein
ICOLMEJK_00483 2.7e-272 S ABC transporter, ATP-binding protein
ICOLMEJK_00484 1.8e-139 S Putative ABC-transporter type IV
ICOLMEJK_00485 8.3e-105 NU mannosyl-glycoprotein
ICOLMEJK_00486 1.2e-247 brnQ U Component of the transport system for branched-chain amino acids
ICOLMEJK_00487 3e-229 S Uncharacterized protein conserved in bacteria (DUF2325)
ICOLMEJK_00488 1.6e-39 L Transposase
ICOLMEJK_00489 8.8e-95 L 4.5 Transposon and IS
ICOLMEJK_00490 1.8e-154 csd1 3.5.1.28 G domain, Protein
ICOLMEJK_00491 4.3e-165 G Major Facilitator Superfamily
ICOLMEJK_00492 2.7e-60 D CobQ CobB MinD ParA nucleotide binding domain protein
ICOLMEJK_00493 1.9e-46
ICOLMEJK_00494 9.3e-19
ICOLMEJK_00496 7.7e-100 L Helix-turn-helix domain
ICOLMEJK_00497 2.4e-125 L Transposase IS66 family
ICOLMEJK_00498 5e-72 L Helix-turn-helix domain
ICOLMEJK_00499 1.2e-67 yqkB S Belongs to the HesB IscA family
ICOLMEJK_00502 1.3e-105 wecD3 K PFAM GCN5-related N-acetyltransferase
ICOLMEJK_00503 1.9e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICOLMEJK_00504 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
ICOLMEJK_00505 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
ICOLMEJK_00506 1.2e-171 malR K Transcriptional regulator, LacI family
ICOLMEJK_00507 3.6e-208 phbA 2.3.1.9 I Belongs to the thiolase family
ICOLMEJK_00508 6.9e-256 malT G Major Facilitator
ICOLMEJK_00509 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
ICOLMEJK_00510 9.3e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
ICOLMEJK_00511 1.7e-71
ICOLMEJK_00512 7.4e-88 2.7.6.5 T Region found in RelA / SpoT proteins
ICOLMEJK_00513 5.8e-115 K response regulator
ICOLMEJK_00514 7.4e-220 sptS 2.7.13.3 T Histidine kinase
ICOLMEJK_00515 4.1e-212 yfeO P Voltage gated chloride channel
ICOLMEJK_00516 2.4e-256 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
ICOLMEJK_00517 1.1e-135 puuD S peptidase C26
ICOLMEJK_00518 1.9e-166 yvgN C Aldo keto reductase
ICOLMEJK_00519 1.2e-181 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
ICOLMEJK_00520 2.6e-129 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
ICOLMEJK_00521 7.3e-86 hmpT S ECF-type riboflavin transporter, S component
ICOLMEJK_00523 3.3e-64 XK27_01125 L PFAM IS66 Orf2 family protein
ICOLMEJK_00524 2.1e-134 L hmm pf00665
ICOLMEJK_00525 1e-38 comGC U competence protein ComGC
ICOLMEJK_00526 9.9e-36 NU general secretion pathway protein
ICOLMEJK_00527 1.3e-84 L transposase, IS605 OrfB family
ICOLMEJK_00528 3.9e-29 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
ICOLMEJK_00529 5.2e-89 L hmm pf00665
ICOLMEJK_00531 1.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICOLMEJK_00532 2.8e-266 yfnA E amino acid
ICOLMEJK_00533 3.5e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ICOLMEJK_00534 2.8e-45 1.3.5.4 S FMN binding
ICOLMEJK_00535 2.9e-221 norA EGP Major facilitator Superfamily
ICOLMEJK_00536 2e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ICOLMEJK_00537 3.3e-155 metQ1 P Belongs to the nlpA lipoprotein family
ICOLMEJK_00538 1.9e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICOLMEJK_00539 3.1e-103 metI P ABC transporter permease
ICOLMEJK_00540 5.7e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ICOLMEJK_00541 1.2e-249 clcA P chloride
ICOLMEJK_00542 6.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
ICOLMEJK_00543 1.4e-102 proW P ABC transporter, permease protein
ICOLMEJK_00544 8.8e-139 proV E ABC transporter, ATP-binding protein
ICOLMEJK_00545 1.4e-108 proWZ P ABC transporter permease
ICOLMEJK_00546 2.1e-160 proX M ABC transporter, substrate-binding protein, QAT family
ICOLMEJK_00547 1.8e-75 K Transcriptional regulator
ICOLMEJK_00548 4.8e-121 1.6.5.2 GM NAD(P)H-binding
ICOLMEJK_00549 1.8e-07
ICOLMEJK_00550 1.1e-204 5.4.2.7 G Metalloenzyme superfamily
ICOLMEJK_00551 0.0 cadA P P-type ATPase
ICOLMEJK_00552 1.4e-130 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
ICOLMEJK_00553 1.2e-123
ICOLMEJK_00554 2.6e-52 S Sugar efflux transporter for intercellular exchange
ICOLMEJK_00555 2.9e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
ICOLMEJK_00557 0.0 L Helicase C-terminal domain protein
ICOLMEJK_00558 7.1e-81 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
ICOLMEJK_00559 3.8e-176 S Aldo keto reductase
ICOLMEJK_00561 2.2e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICOLMEJK_00562 2.2e-262 glnA 6.3.1.2 E glutamine synthetase
ICOLMEJK_00563 1.2e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ICOLMEJK_00564 5.9e-22 S Protein of unknown function (DUF3042)
ICOLMEJK_00565 1.3e-66 yqhL P Rhodanese-like protein
ICOLMEJK_00566 1.5e-183 glk 2.7.1.2 G Glucokinase
ICOLMEJK_00567 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
ICOLMEJK_00568 8.4e-106 gluP 3.4.21.105 S Peptidase, S54 family
ICOLMEJK_00569 4.9e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICOLMEJK_00570 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ICOLMEJK_00571 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
ICOLMEJK_00572 0.0 S membrane
ICOLMEJK_00573 3.1e-68 yneR S Belongs to the HesB IscA family
ICOLMEJK_00574 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ICOLMEJK_00575 3.1e-116 udk 2.7.1.48 F Cytidine monophosphokinase
ICOLMEJK_00576 4.7e-114 rlpA M PFAM NLP P60 protein
ICOLMEJK_00577 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICOLMEJK_00578 1.5e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ICOLMEJK_00579 6.7e-59 yodB K Transcriptional regulator, HxlR family
ICOLMEJK_00580 5.3e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
ICOLMEJK_00581 8.3e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICOLMEJK_00582 1.6e-42 acyP 3.6.1.7 C Belongs to the acylphosphatase family
ICOLMEJK_00583 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICOLMEJK_00584 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
ICOLMEJK_00585 6.4e-230 V MatE
ICOLMEJK_00586 2.2e-182 yjeM E Amino Acid
ICOLMEJK_00587 3.2e-62 yjeM E Amino Acid
ICOLMEJK_00588 3.7e-279 arlS 2.7.13.3 T Histidine kinase
ICOLMEJK_00589 1.5e-121 K response regulator
ICOLMEJK_00590 3.6e-129 yebC K Transcriptional regulatory protein
ICOLMEJK_00591 1.6e-130
ICOLMEJK_00592 2.7e-180 ccpA K catabolite control protein A
ICOLMEJK_00593 4.4e-208 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ICOLMEJK_00594 4.6e-26
ICOLMEJK_00595 1e-35 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ICOLMEJK_00596 8.4e-146 ykuT M mechanosensitive ion channel
ICOLMEJK_00597 4.4e-152 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
ICOLMEJK_00598 1.1e-74 ykuL S (CBS) domain
ICOLMEJK_00599 3.2e-92 S Phosphoesterase
ICOLMEJK_00600 3.6e-100 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ICOLMEJK_00601 9.2e-139 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ICOLMEJK_00602 4.6e-97 yslB S Protein of unknown function (DUF2507)
ICOLMEJK_00603 1.4e-53 trxA O Belongs to the thioredoxin family
ICOLMEJK_00604 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ICOLMEJK_00605 1.7e-85 cvpA S Colicin V production protein
ICOLMEJK_00606 2.3e-47 yrzB S Belongs to the UPF0473 family
ICOLMEJK_00607 4.7e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ICOLMEJK_00608 1.6e-42 yrzL S Belongs to the UPF0297 family
ICOLMEJK_00609 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICOLMEJK_00610 1.4e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ICOLMEJK_00611 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
ICOLMEJK_00612 1.4e-30 yajC U Preprotein translocase
ICOLMEJK_00613 3.6e-186 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
ICOLMEJK_00614 1e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ICOLMEJK_00615 4.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ICOLMEJK_00616 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ICOLMEJK_00617 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ICOLMEJK_00618 3.1e-77 mraZ K Belongs to the MraZ family
ICOLMEJK_00619 1.8e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ICOLMEJK_00620 1e-55 ftsL D Cell division protein FtsL
ICOLMEJK_00621 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
ICOLMEJK_00622 1.7e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICOLMEJK_00623 4.2e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICOLMEJK_00624 1.5e-203 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ICOLMEJK_00625 3e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ICOLMEJK_00626 2.1e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ICOLMEJK_00627 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ICOLMEJK_00628 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ICOLMEJK_00629 3.2e-40 yggT S YGGT family
ICOLMEJK_00630 1.7e-145 ylmH S S4 domain protein
ICOLMEJK_00631 1.9e-42 divIVA D DivIVA domain protein
ICOLMEJK_00632 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ICOLMEJK_00633 4.7e-31 cspA K Cold shock protein
ICOLMEJK_00634 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
ICOLMEJK_00636 8.5e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ICOLMEJK_00637 1.5e-214 iscS 2.8.1.7 E Aminotransferase class V
ICOLMEJK_00638 7.5e-58 XK27_04120 S Putative amino acid metabolism
ICOLMEJK_00639 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ICOLMEJK_00640 3.2e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
ICOLMEJK_00641 2.2e-117 S Repeat protein
ICOLMEJK_00642 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ICOLMEJK_00643 1.5e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICOLMEJK_00644 3.3e-286 UW LPXTG-motif cell wall anchor domain protein
ICOLMEJK_00645 1.5e-29 UW LPXTG-motif cell wall anchor domain protein
ICOLMEJK_00646 1.3e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ICOLMEJK_00647 4.6e-260 lysC 2.7.2.4 E Belongs to the aspartokinase family
ICOLMEJK_00648 2.6e-244 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
ICOLMEJK_00649 4.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
ICOLMEJK_00650 6.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
ICOLMEJK_00651 5.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICOLMEJK_00652 3.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
ICOLMEJK_00653 2.1e-216 patA 2.6.1.1 E Aminotransferase
ICOLMEJK_00654 2e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICOLMEJK_00655 1.9e-124 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
ICOLMEJK_00656 1e-51 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
ICOLMEJK_00657 1.2e-55
ICOLMEJK_00659 1.1e-137 mltD CBM50 M NlpC P60 family protein
ICOLMEJK_00660 5.7e-29
ICOLMEJK_00661 9.3e-183 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
ICOLMEJK_00662 9.8e-32 ykzG S Belongs to the UPF0356 family
ICOLMEJK_00663 3e-81
ICOLMEJK_00664 1.3e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ICOLMEJK_00665 8.8e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
ICOLMEJK_00666 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
ICOLMEJK_00667 1.3e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ICOLMEJK_00668 2.7e-274 lpdA 1.8.1.4 C Dehydrogenase
ICOLMEJK_00669 1.4e-47 yktA S Belongs to the UPF0223 family
ICOLMEJK_00670 2.4e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
ICOLMEJK_00671 0.0 typA T GTP-binding protein TypA
ICOLMEJK_00672 2e-222 ftsW D Belongs to the SEDS family
ICOLMEJK_00673 2e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
ICOLMEJK_00674 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
ICOLMEJK_00675 2.5e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ICOLMEJK_00676 2.5e-197 ylbL T Belongs to the peptidase S16 family
ICOLMEJK_00677 1.1e-78 comEA L Competence protein ComEA
ICOLMEJK_00678 7.6e-88 comEB 3.5.4.12 F ComE operon protein 2
ICOLMEJK_00679 1.4e-167 comEC S Competence protein ComEC
ICOLMEJK_00680 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ICOLMEJK_00681 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ICOLMEJK_00682 1.8e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ICOLMEJK_00683 1.2e-241 M Glycosyl transferase family group 2
ICOLMEJK_00685 7e-228 aadAT EK Aminotransferase, class I
ICOLMEJK_00686 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ICOLMEJK_00687 1.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ICOLMEJK_00688 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
ICOLMEJK_00689 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ICOLMEJK_00690 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ICOLMEJK_00691 1.8e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICOLMEJK_00692 7.2e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ICOLMEJK_00693 3.8e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICOLMEJK_00694 6.5e-207 yacL S domain protein
ICOLMEJK_00695 7.8e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ICOLMEJK_00696 6.2e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
ICOLMEJK_00697 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
ICOLMEJK_00698 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ICOLMEJK_00699 1.5e-266 pepC 3.4.22.40 E Peptidase C1-like family
ICOLMEJK_00700 8.2e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
ICOLMEJK_00701 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICOLMEJK_00702 1.1e-119 tcyB E ABC transporter
ICOLMEJK_00703 1.2e-213 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
ICOLMEJK_00704 3.5e-168 I alpha/beta hydrolase fold
ICOLMEJK_00705 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICOLMEJK_00706 0.0 S Bacterial membrane protein, YfhO
ICOLMEJK_00707 8.5e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
ICOLMEJK_00708 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
ICOLMEJK_00710 7.3e-50
ICOLMEJK_00711 3.3e-51 rarA L recombination factor protein RarA
ICOLMEJK_00712 4.4e-112 rarA L recombination factor protein RarA
ICOLMEJK_00713 2.3e-145 yxeH S hydrolase
ICOLMEJK_00714 3.6e-268 ywfO S HD domain protein
ICOLMEJK_00715 2.5e-152 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
ICOLMEJK_00716 4.6e-67 ywiB S Domain of unknown function (DUF1934)
ICOLMEJK_00717 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ICOLMEJK_00718 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ICOLMEJK_00719 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICOLMEJK_00720 4.6e-41 rpmE2 J Ribosomal protein L31
ICOLMEJK_00721 1.9e-234 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICOLMEJK_00722 2.7e-163 S Alpha/beta hydrolase of unknown function (DUF915)
ICOLMEJK_00723 2.1e-123 srtA 3.4.22.70 M sortase family
ICOLMEJK_00724 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
ICOLMEJK_00725 6.3e-156 3.2.1.55 GH51 G Right handed beta helix region
ICOLMEJK_00726 1.7e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ICOLMEJK_00727 3.7e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
ICOLMEJK_00728 3.5e-120 pgm3 G Belongs to the phosphoglycerate mutase family
ICOLMEJK_00729 1.8e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICOLMEJK_00730 7e-93 lemA S LemA family
ICOLMEJK_00731 5.8e-158 htpX O Belongs to the peptidase M48B family
ICOLMEJK_00732 2.3e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ICOLMEJK_00733 1.5e-248 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ICOLMEJK_00734 7.5e-14 E Pfam:DUF955
ICOLMEJK_00735 2e-77 2.3.1.128 K Acetyltransferase (GNAT) domain
ICOLMEJK_00736 2.1e-203 lmrB EGP Major facilitator Superfamily
ICOLMEJK_00737 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
ICOLMEJK_00738 5.8e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ICOLMEJK_00739 4.4e-158 sufD O Uncharacterized protein family (UPF0051)
ICOLMEJK_00740 6.5e-42 lytE M LysM domain protein
ICOLMEJK_00741 0.0 oppD EP Psort location Cytoplasmic, score
ICOLMEJK_00742 1.5e-80 lytE M LysM domain protein
ICOLMEJK_00743 7.1e-149 xth 3.1.11.2 L exodeoxyribonuclease III
ICOLMEJK_00744 8.3e-122 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
ICOLMEJK_00745 2.2e-102 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
ICOLMEJK_00746 3.8e-235 preA 1.3.1.1 C 4Fe-4S dicluster domain
ICOLMEJK_00747 3.8e-151 yeaE S Aldo keto
ICOLMEJK_00748 3.5e-76 hsp O Belongs to the small heat shock protein (HSP20) family
ICOLMEJK_00749 7.9e-277 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
ICOLMEJK_00750 4.4e-74 S Psort location Cytoplasmic, score
ICOLMEJK_00751 2.7e-83 S Short repeat of unknown function (DUF308)
ICOLMEJK_00752 1e-23
ICOLMEJK_00753 4.4e-103 V VanZ like family
ICOLMEJK_00754 7.2e-229 cycA E Amino acid permease
ICOLMEJK_00755 4.3e-85 perR P Belongs to the Fur family
ICOLMEJK_00756 9.6e-256 EGP Major facilitator Superfamily
ICOLMEJK_00757 6.9e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ICOLMEJK_00758 0.0 helD 3.6.4.12 L DNA helicase
ICOLMEJK_00759 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
ICOLMEJK_00760 1.5e-183 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
ICOLMEJK_00761 1e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICOLMEJK_00762 1.8e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ICOLMEJK_00763 4.4e-228 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
ICOLMEJK_00764 1.9e-175
ICOLMEJK_00765 5.2e-130 cobB K SIR2 family
ICOLMEJK_00767 2e-160 yunF F Protein of unknown function DUF72
ICOLMEJK_00768 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICOLMEJK_00769 3.9e-153 tatD L hydrolase, TatD family
ICOLMEJK_00770 5.5e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ICOLMEJK_00771 6.8e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ICOLMEJK_00772 6.8e-37 veg S Biofilm formation stimulator VEG
ICOLMEJK_00773 6.9e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ICOLMEJK_00774 7.6e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
ICOLMEJK_00775 7.7e-123 fhuC P ABC transporter
ICOLMEJK_00776 1.2e-127 znuB U ABC 3 transport family
ICOLMEJK_00777 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
ICOLMEJK_00778 1.7e-241 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICOLMEJK_00779 3.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICOLMEJK_00780 3.2e-164 czcD P cation diffusion facilitator family transporter
ICOLMEJK_00781 9.1e-124 sirR K iron dependent repressor
ICOLMEJK_00782 1.9e-29 cspC K Cold shock protein
ICOLMEJK_00783 7.6e-127 thrE S Putative threonine/serine exporter
ICOLMEJK_00784 2.5e-80 S Threonine/Serine exporter, ThrE
ICOLMEJK_00785 8.8e-119 lssY 3.6.1.27 I phosphatase
ICOLMEJK_00786 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
ICOLMEJK_00787 2.3e-276 lysP E amino acid
ICOLMEJK_00788 4.8e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
ICOLMEJK_00794 2e-103 S Hydrolases of the alpha beta superfamily
ICOLMEJK_00795 5.3e-66 S Hydrolases of the alpha beta superfamily
ICOLMEJK_00796 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
ICOLMEJK_00797 3.4e-77 ctsR K Belongs to the CtsR family
ICOLMEJK_00798 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ICOLMEJK_00799 1.8e-110 K Bacterial regulatory proteins, tetR family
ICOLMEJK_00800 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICOLMEJK_00801 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICOLMEJK_00802 1e-199 ykiI
ICOLMEJK_00803 7.9e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ICOLMEJK_00804 1.2e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ICOLMEJK_00805 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
ICOLMEJK_00806 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ICOLMEJK_00807 9.4e-38 yheA S Belongs to the UPF0342 family
ICOLMEJK_00808 1.3e-221 yhaO L Ser Thr phosphatase family protein
ICOLMEJK_00809 0.0 L AAA domain
ICOLMEJK_00810 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ICOLMEJK_00812 1.2e-76 hit FG histidine triad
ICOLMEJK_00813 3.9e-136 ecsA V ABC transporter, ATP-binding protein
ICOLMEJK_00814 1.1e-217 ecsB U ABC transporter
ICOLMEJK_00815 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ICOLMEJK_00816 2.4e-22 S YSIRK type signal peptide
ICOLMEJK_00817 1.1e-107 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
ICOLMEJK_00818 5.9e-166 2.7.7.7, 3.4.21.110 D Leucine-rich repeat (LRR) protein
ICOLMEJK_00819 1.3e-07 D nuclear chromosome segregation
ICOLMEJK_00820 4.8e-266 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
ICOLMEJK_00821 3.4e-180 iolS C Aldo keto reductase
ICOLMEJK_00822 1.4e-116 glsA 3.5.1.2 E Belongs to the glutaminase family
ICOLMEJK_00823 7.6e-11 glsA 3.5.1.2 E Belongs to the glutaminase family
ICOLMEJK_00824 2.2e-57 ytzB S Small secreted protein
ICOLMEJK_00825 1.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
ICOLMEJK_00826 7e-175 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
ICOLMEJK_00827 2.3e-197 XK27_09615 S reductase
ICOLMEJK_00828 6e-100 nqr 1.5.1.36 S reductase
ICOLMEJK_00829 5.9e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICOLMEJK_00830 5.6e-178 K Transcriptional regulator, LacI family
ICOLMEJK_00831 1e-259 G Major Facilitator
ICOLMEJK_00832 5.8e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ICOLMEJK_00833 2.3e-310 carB 6.3.5.5 F Carbamoyl-phosphate synthase
ICOLMEJK_00834 6.7e-240 carB 6.3.5.5 F Carbamoyl-phosphate synthase
ICOLMEJK_00835 8.2e-243 G Major Facilitator
ICOLMEJK_00836 9.7e-08 G Major Facilitator
ICOLMEJK_00837 1.8e-161 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
ICOLMEJK_00838 1.3e-156 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
ICOLMEJK_00839 9.2e-278 M domain protein
ICOLMEJK_00840 8.8e-61 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
ICOLMEJK_00841 7.5e-195 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
ICOLMEJK_00842 6.2e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
ICOLMEJK_00843 2.2e-72
ICOLMEJK_00844 4.6e-26
ICOLMEJK_00845 2.2e-262 pgi 5.3.1.9 G Belongs to the GPI family
ICOLMEJK_00846 1.7e-100 lacA 2.3.1.79 S Transferase hexapeptide repeat
ICOLMEJK_00847 3.1e-153 glcU U sugar transport
ICOLMEJK_00848 6e-269 yclK 2.7.13.3 T Histidine kinase
ICOLMEJK_00849 2.6e-132 K response regulator
ICOLMEJK_00850 2.8e-53 sip L Belongs to the 'phage' integrase family
ICOLMEJK_00851 4.6e-13 K Helix-turn-helix XRE-family like proteins
ICOLMEJK_00852 5.9e-10 S Helix-turn-helix domain
ICOLMEJK_00856 1e-96 S DNA primase
ICOLMEJK_00859 4.3e-16 S Phage head-tail joining protein
ICOLMEJK_00860 1.2e-31 L HNH endonuclease
ICOLMEJK_00861 1.3e-26 terS L Phage terminase, small subunit
ICOLMEJK_00862 3.6e-201 terL S overlaps another CDS with the same product name
ICOLMEJK_00863 7.1e-137 S Phage portal protein
ICOLMEJK_00864 5.2e-186 S Caudovirus prohead serine protease
ICOLMEJK_00865 2.5e-17 S Phage gp6-like head-tail connector protein
ICOLMEJK_00866 1.4e-23
ICOLMEJK_00867 1.5e-08 arpU S Phage transcriptional regulator, ArpU family
ICOLMEJK_00869 2.5e-88
ICOLMEJK_00870 7.1e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ICOLMEJK_00871 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
ICOLMEJK_00872 7.2e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
ICOLMEJK_00873 9.8e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ICOLMEJK_00874 1.5e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ICOLMEJK_00875 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ICOLMEJK_00876 7.6e-09
ICOLMEJK_00877 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
ICOLMEJK_00878 1.4e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
ICOLMEJK_00879 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ICOLMEJK_00880 3.1e-237 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ICOLMEJK_00881 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICOLMEJK_00882 3.9e-162 S Tetratricopeptide repeat
ICOLMEJK_00883 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICOLMEJK_00884 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ICOLMEJK_00885 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
ICOLMEJK_00886 5.6e-141 holA 2.7.7.7 L DNA polymerase III delta subunit
ICOLMEJK_00887 1.1e-138 comEC S Competence protein ComEC
ICOLMEJK_00888 1.3e-270 pipD E Dipeptidase
ICOLMEJK_00889 3.8e-310 yjbQ P TrkA C-terminal domain protein
ICOLMEJK_00890 1e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
ICOLMEJK_00891 1.4e-289 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ICOLMEJK_00892 4.2e-89
ICOLMEJK_00893 3.6e-35
ICOLMEJK_00894 1.7e-99 K DNA-templated transcription, initiation
ICOLMEJK_00895 1e-125
ICOLMEJK_00896 4.8e-64 K Transcriptional regulator, HxlR family
ICOLMEJK_00897 2.2e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ICOLMEJK_00898 8.2e-141 epsB M biosynthesis protein
ICOLMEJK_00899 2.6e-116 ywqD 2.7.10.1 D Capsular exopolysaccharide family
ICOLMEJK_00900 2.1e-53 rfbP M Bacterial sugar transferase
ICOLMEJK_00901 1.8e-37 rfbP M Bacterial sugar transferase
ICOLMEJK_00902 7e-134 M Glycosyl transferase 4-like
ICOLMEJK_00903 1.5e-67 M Glycosyl transferases group 1
ICOLMEJK_00904 3.3e-83 M Glycosyl transferases group 1
ICOLMEJK_00905 5.7e-42
ICOLMEJK_00906 2.4e-17 epsH M Hexapeptide repeat of succinyl-transferase
ICOLMEJK_00907 6.1e-44 M Glycosyltransferase like family 2
ICOLMEJK_00908 2.9e-91 rfbX S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ICOLMEJK_00910 2.7e-85 S Protein of unknown function (DUF1440)
ICOLMEJK_00911 9.3e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ICOLMEJK_00912 1.8e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
ICOLMEJK_00913 2.7e-161 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
ICOLMEJK_00914 2.4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
ICOLMEJK_00915 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
ICOLMEJK_00916 1.3e-85 ypmB S Protein conserved in bacteria
ICOLMEJK_00917 5.2e-122 dnaD L DnaD domain protein
ICOLMEJK_00918 1.4e-162 EG EamA-like transporter family
ICOLMEJK_00919 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
ICOLMEJK_00920 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ICOLMEJK_00921 1.3e-99 ypsA S Belongs to the UPF0398 family
ICOLMEJK_00922 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ICOLMEJK_00923 1.1e-24 F Belongs to the NrdI family
ICOLMEJK_00924 2.4e-46 F Belongs to the NrdI family
ICOLMEJK_00925 3.6e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
ICOLMEJK_00926 1.8e-71 rnhA 3.1.26.4 L Ribonuclease HI
ICOLMEJK_00927 1.5e-65 esbA S Family of unknown function (DUF5322)
ICOLMEJK_00928 2.8e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ICOLMEJK_00929 1.8e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ICOLMEJK_00930 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
ICOLMEJK_00931 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
ICOLMEJK_00932 0.0 FbpA K Fibronectin-binding protein
ICOLMEJK_00933 6.6e-159 degV S EDD domain protein, DegV family
ICOLMEJK_00934 1.7e-93
ICOLMEJK_00935 9.5e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
ICOLMEJK_00936 1.2e-157 gspA M family 8
ICOLMEJK_00937 3.5e-157 S Alpha beta hydrolase
ICOLMEJK_00938 3.4e-94 K Acetyltransferase (GNAT) domain
ICOLMEJK_00941 9.6e-64 XK27_01125 L PFAM IS66 Orf2 family protein
ICOLMEJK_00942 3.2e-192 L Transposase IS66 family
ICOLMEJK_00943 1.6e-78 yphH S Cupin domain
ICOLMEJK_00944 2.9e-73 yeaL S UPF0756 membrane protein
ICOLMEJK_00945 2e-242 EGP Major facilitator Superfamily
ICOLMEJK_00946 3.9e-72 copY K Copper transport repressor CopY TcrY
ICOLMEJK_00947 8.5e-246 yhdP S Transporter associated domain
ICOLMEJK_00948 0.0 ubiB S ABC1 family
ICOLMEJK_00949 5.6e-144 S DUF218 domain
ICOLMEJK_00950 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICOLMEJK_00951 4.1e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICOLMEJK_00952 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICOLMEJK_00953 0.0 uvrA3 L excinuclease ABC, A subunit
ICOLMEJK_00954 2.6e-121 S SNARE associated Golgi protein
ICOLMEJK_00955 1.4e-231 N Uncharacterized conserved protein (DUF2075)
ICOLMEJK_00956 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ICOLMEJK_00958 1e-254 yifK E Amino acid permease
ICOLMEJK_00959 5.1e-156 endA V DNA/RNA non-specific endonuclease
ICOLMEJK_00960 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICOLMEJK_00961 2.1e-39 ybaN S Protein of unknown function (DUF454)
ICOLMEJK_00962 1.3e-70 S Protein of unknown function (DUF3290)
ICOLMEJK_00963 8.1e-114 yviA S Protein of unknown function (DUF421)
ICOLMEJK_00964 2.6e-163 S Alpha/beta hydrolase of unknown function (DUF915)
ICOLMEJK_00965 1.8e-19
ICOLMEJK_00966 1.1e-89 ntd 2.4.2.6 F Nucleoside
ICOLMEJK_00967 1.4e-150 3.1.3.102, 3.1.3.104 S hydrolase
ICOLMEJK_00968 7.6e-42 yrvD S Pfam:DUF1049
ICOLMEJK_00970 1.1e-10 S Phage derived protein Gp49-like (DUF891)
ICOLMEJK_00973 2.3e-164 I alpha/beta hydrolase fold
ICOLMEJK_00974 2.5e-115 yfbR S HD containing hydrolase-like enzyme
ICOLMEJK_00975 1.5e-13
ICOLMEJK_00976 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ICOLMEJK_00977 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ICOLMEJK_00978 2.7e-244 steT E amino acid
ICOLMEJK_00979 1e-159 rapZ S Displays ATPase and GTPase activities
ICOLMEJK_00980 9.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
ICOLMEJK_00981 3.4e-169 whiA K May be required for sporulation
ICOLMEJK_00983 1.5e-14
ICOLMEJK_00984 9.1e-240 glpT G Major Facilitator Superfamily
ICOLMEJK_00985 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ICOLMEJK_00987 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ICOLMEJK_00988 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
ICOLMEJK_00989 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ICOLMEJK_00990 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ICOLMEJK_00991 8e-45 L hmm pf00665
ICOLMEJK_00992 2.9e-53 3.6.4.12 L DnaB-like helicase C terminal domain
ICOLMEJK_00995 2.5e-104 pre D plasmid recombination enzyme
ICOLMEJK_00996 1.7e-16 L Replication protein
ICOLMEJK_00997 5.8e-30 L Replication protein
ICOLMEJK_00998 1.8e-96 xerC L Phage integrase, N-terminal SAM-like domain
ICOLMEJK_00999 7.7e-98 D Cellulose biosynthesis protein BcsQ
ICOLMEJK_01001 6.9e-63 S Homeodomain-like domain
ICOLMEJK_01003 7e-40
ICOLMEJK_01004 2e-17 S Bacterial membrane protein, YfhO
ICOLMEJK_01005 7.8e-147 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICOLMEJK_01006 2.9e-103 2.1.1.72 S Adenine-specific methyltransferase EcoRI
ICOLMEJK_01007 9.6e-118 L HNH endonuclease
ICOLMEJK_01008 1.4e-218 3.6.4.12 L DnaB-like helicase C terminal domain
ICOLMEJK_01009 2.1e-08 tnp L MULE transposase domain
ICOLMEJK_01010 5.8e-64 yeaO S Protein of unknown function, DUF488
ICOLMEJK_01011 2.2e-119 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
ICOLMEJK_01012 2.2e-202 3.1.3.1 S associated with various cellular activities
ICOLMEJK_01013 7.9e-233 S Putative metallopeptidase domain
ICOLMEJK_01014 3.6e-48
ICOLMEJK_01015 0.0 pepO 3.4.24.71 O Peptidase family M13
ICOLMEJK_01016 2.7e-109 K Helix-turn-helix domain
ICOLMEJK_01017 8.7e-87 ymdB S Macro domain protein
ICOLMEJK_01018 1.7e-25 EGP Major facilitator Superfamily
ICOLMEJK_01019 1.2e-80 EGP Major facilitator Superfamily
ICOLMEJK_01020 5.2e-61 EGP Major facilitator Superfamily
ICOLMEJK_01021 6e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICOLMEJK_01022 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ICOLMEJK_01023 4.5e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
ICOLMEJK_01024 2.2e-191 ysaB V FtsX-like permease family
ICOLMEJK_01026 3.8e-24 ytbE 1.1.1.346 S Aldo keto reductase
ICOLMEJK_01027 5.2e-136 pnuC H nicotinamide mononucleotide transporter
ICOLMEJK_01028 1.7e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ICOLMEJK_01029 4.8e-202
ICOLMEJK_01030 6.5e-51
ICOLMEJK_01031 2.4e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
ICOLMEJK_01032 3.9e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ICOLMEJK_01033 1.7e-123 lrgB M LrgB-like family
ICOLMEJK_01034 1.9e-66 lrgA S LrgA family
ICOLMEJK_01035 4e-125 lytT K response regulator receiver
ICOLMEJK_01036 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
ICOLMEJK_01037 6.8e-148 f42a O Band 7 protein
ICOLMEJK_01038 2.2e-262 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
ICOLMEJK_01039 7.9e-154 yitU 3.1.3.104 S hydrolase
ICOLMEJK_01040 9.2e-39 S Cytochrome B5
ICOLMEJK_01041 2e-112 nreC K PFAM regulatory protein LuxR
ICOLMEJK_01042 4.8e-157 hipB K Helix-turn-helix
ICOLMEJK_01043 2.8e-57 yitW S Iron-sulfur cluster assembly protein
ICOLMEJK_01044 1.8e-270 sufB O assembly protein SufB
ICOLMEJK_01045 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
ICOLMEJK_01046 4.1e-231 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICOLMEJK_01047 5.8e-236 sufD O FeS assembly protein SufD
ICOLMEJK_01048 6.5e-145 sufC O FeS assembly ATPase SufC
ICOLMEJK_01049 7e-39 S Cytochrome B5
ICOLMEJK_01050 1.3e-73 elaA S Gnat family
ICOLMEJK_01051 1e-119 GM NmrA-like family
ICOLMEJK_01052 8.1e-51 hxlR K Transcriptional regulator, HxlR family
ICOLMEJK_01053 1.8e-107 XK27_02070 S Nitroreductase family
ICOLMEJK_01054 1.1e-71 K Transcriptional regulator, HxlR family
ICOLMEJK_01055 4.7e-233
ICOLMEJK_01056 8e-208 EGP Major facilitator Superfamily
ICOLMEJK_01057 9.8e-255 pepC 3.4.22.40 E aminopeptidase
ICOLMEJK_01058 4.2e-110 ylbE GM NAD dependent epimerase dehydratase family protein
ICOLMEJK_01059 0.0 pepN 3.4.11.2 E aminopeptidase
ICOLMEJK_01060 1.8e-88 folT S ECF transporter, substrate-specific component
ICOLMEJK_01061 1.5e-30 yjaB_1 K Acetyltransferase (GNAT) domain
ICOLMEJK_01062 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
ICOLMEJK_01063 1.4e-253 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
ICOLMEJK_01064 7e-153 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
ICOLMEJK_01065 7.1e-80 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
ICOLMEJK_01066 1.4e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICOLMEJK_01067 5.3e-184 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
ICOLMEJK_01068 9.4e-112
ICOLMEJK_01069 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
ICOLMEJK_01070 2.7e-105 lmrB EGP Major facilitator Superfamily
ICOLMEJK_01071 2.9e-19 K Transcriptional regulator
ICOLMEJK_01072 6.9e-19 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ICOLMEJK_01073 2.6e-104 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ICOLMEJK_01074 7.3e-86 uspA T Belongs to the universal stress protein A family
ICOLMEJK_01075 4e-275 pepV 3.5.1.18 E dipeptidase PepV
ICOLMEJK_01076 4.5e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICOLMEJK_01077 3.3e-300 ytgP S Polysaccharide biosynthesis protein
ICOLMEJK_01078 7.6e-42
ICOLMEJK_01079 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICOLMEJK_01080 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ICOLMEJK_01081 1.8e-93 tag 3.2.2.20 L glycosylase
ICOLMEJK_01082 3.3e-167 L restriction endonuclease
ICOLMEJK_01083 1.1e-95 mrr L restriction endonuclease
ICOLMEJK_01084 5.9e-35 L PLD-like domain
ICOLMEJK_01085 0.0 L PLD-like domain
ICOLMEJK_01087 2.4e-178 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
ICOLMEJK_01088 2.2e-180 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICOLMEJK_01089 3.9e-94 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
ICOLMEJK_01090 5.7e-222 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
ICOLMEJK_01091 7.4e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
ICOLMEJK_01092 3.6e-102 T Ion transport 2 domain protein
ICOLMEJK_01093 0.0 S Bacterial membrane protein YfhO
ICOLMEJK_01094 1.3e-197 G Transporter, major facilitator family protein
ICOLMEJK_01095 3.5e-108 yvrI K sigma factor activity
ICOLMEJK_01096 5e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
ICOLMEJK_01097 5.4e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
ICOLMEJK_01098 9.6e-294 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICOLMEJK_01099 0.0 asnB 6.3.5.4 E Asparagine synthase
ICOLMEJK_01100 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ICOLMEJK_01101 8.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ICOLMEJK_01102 8.2e-129 jag S R3H domain protein
ICOLMEJK_01103 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICOLMEJK_01104 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ICOLMEJK_01105 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
ICOLMEJK_01106 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICOLMEJK_01107 5.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ICOLMEJK_01108 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
ICOLMEJK_01109 3.3e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICOLMEJK_01110 1.5e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
ICOLMEJK_01111 2.7e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
ICOLMEJK_01112 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICOLMEJK_01113 2.7e-39 ptsH G phosphocarrier protein HPR
ICOLMEJK_01114 8.3e-27
ICOLMEJK_01115 0.0 clpE O Belongs to the ClpA ClpB family
ICOLMEJK_01116 4.9e-100 S Pfam:DUF3816
ICOLMEJK_01117 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
ICOLMEJK_01118 1.6e-115
ICOLMEJK_01119 9.5e-158 V ABC transporter, ATP-binding protein
ICOLMEJK_01120 1e-63 gntR1 K Transcriptional regulator, GntR family
ICOLMEJK_01121 6e-255 S Peptidase, M23
ICOLMEJK_01122 3.7e-235 S Peptidase, M23
ICOLMEJK_01123 7.7e-41 doc S Fic/DOC family
ICOLMEJK_01124 8.5e-11
ICOLMEJK_01125 3e-22 S YoeB-like toxin of bacterial type II toxin-antitoxin system
ICOLMEJK_01126 5.5e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
ICOLMEJK_01140 9.6e-12 ard S Antirestriction protein (ArdA)
ICOLMEJK_01144 8e-38
ICOLMEJK_01146 5.4e-70 D CobQ CobB MinD ParA nucleotide binding domain protein
ICOLMEJK_01147 3.2e-17 S Replication initiator protein A (RepA) N-terminus
ICOLMEJK_01148 6.9e-92 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
ICOLMEJK_01149 2.7e-82 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
ICOLMEJK_01150 3.5e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
ICOLMEJK_01151 4.6e-263 argH 4.3.2.1 E argininosuccinate lyase
ICOLMEJK_01152 3.2e-82 bioY S BioY family
ICOLMEJK_01153 1.2e-172 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ICOLMEJK_01154 1.7e-182 phoH T phosphate starvation-inducible protein PhoH
ICOLMEJK_01155 6.1e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ICOLMEJK_01156 2.1e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
ICOLMEJK_01157 5.1e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ICOLMEJK_01158 3.8e-145 recO L Involved in DNA repair and RecF pathway recombination
ICOLMEJK_01159 1.7e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
ICOLMEJK_01160 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
ICOLMEJK_01161 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ICOLMEJK_01162 4.2e-206 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ICOLMEJK_01163 1.1e-220 patA 2.6.1.1 E Aminotransferase
ICOLMEJK_01164 1.1e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
ICOLMEJK_01165 2.9e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ICOLMEJK_01166 2.8e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
ICOLMEJK_01167 2.3e-30 S Protein of unknown function (DUF2929)
ICOLMEJK_01168 0.0 dnaE 2.7.7.7 L DNA polymerase
ICOLMEJK_01169 3.6e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
ICOLMEJK_01170 1.6e-168 cvfB S S1 domain
ICOLMEJK_01171 7e-164 xerD D recombinase XerD
ICOLMEJK_01172 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICOLMEJK_01173 2.2e-137 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ICOLMEJK_01174 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ICOLMEJK_01175 8.4e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ICOLMEJK_01176 2.6e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ICOLMEJK_01177 7.7e-191 ypbB 5.1.3.1 S Helix-turn-helix domain
ICOLMEJK_01178 1e-265 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
ICOLMEJK_01179 7.2e-13 M Lysin motif
ICOLMEJK_01180 7.6e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
ICOLMEJK_01181 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
ICOLMEJK_01182 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
ICOLMEJK_01183 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ICOLMEJK_01184 1.5e-236 S Tetratricopeptide repeat protein
ICOLMEJK_01185 6.9e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ICOLMEJK_01186 0.0 yfmR S ABC transporter, ATP-binding protein
ICOLMEJK_01187 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ICOLMEJK_01188 1.2e-88 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ICOLMEJK_01189 4.5e-112 hlyIII S protein, hemolysin III
ICOLMEJK_01190 2.2e-151 DegV S EDD domain protein, DegV family
ICOLMEJK_01191 8.3e-168 ypmR E lipolytic protein G-D-S-L family
ICOLMEJK_01192 2.2e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
ICOLMEJK_01193 4.4e-35 yozE S Belongs to the UPF0346 family
ICOLMEJK_01194 8.4e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ICOLMEJK_01195 3.6e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICOLMEJK_01196 7.1e-161 dprA LU DNA protecting protein DprA
ICOLMEJK_01197 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ICOLMEJK_01198 1.6e-168 lacX 5.1.3.3 G Aldose 1-epimerase
ICOLMEJK_01199 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ICOLMEJK_01200 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICOLMEJK_01201 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICOLMEJK_01202 3.5e-82 F NUDIX domain
ICOLMEJK_01203 2.3e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
ICOLMEJK_01204 1.1e-113 S (CBS) domain
ICOLMEJK_01205 4.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ICOLMEJK_01206 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICOLMEJK_01207 8.1e-39 yabO J S4 domain protein
ICOLMEJK_01208 2.3e-57 divIC D Septum formation initiator
ICOLMEJK_01209 9.8e-67 yabR J RNA binding
ICOLMEJK_01210 4.8e-252 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ICOLMEJK_01211 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ICOLMEJK_01212 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICOLMEJK_01213 5.2e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ICOLMEJK_01214 5.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICOLMEJK_01215 2.7e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
ICOLMEJK_01216 3.2e-116 devA 3.6.3.25 V ABC transporter, ATP-binding protein
ICOLMEJK_01217 1.1e-163 hrtB V ABC transporter permease
ICOLMEJK_01218 2e-83 ygfC K transcriptional regulator (TetR family)
ICOLMEJK_01219 2.9e-190 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
ICOLMEJK_01220 3.7e-285 mntH P H( )-stimulated, divalent metal cation uptake system
ICOLMEJK_01221 1.9e-31
ICOLMEJK_01222 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ICOLMEJK_01224 7e-93 yxiO S Vacuole effluxer Atg22 like
ICOLMEJK_01225 8.9e-30 yxiO S Vacuole effluxer Atg22 like
ICOLMEJK_01226 1.8e-214 npp S type I phosphodiesterase nucleotide pyrophosphatase
ICOLMEJK_01227 7.6e-10 npp S type I phosphodiesterase nucleotide pyrophosphatase
ICOLMEJK_01228 2.9e-241 E amino acid
ICOLMEJK_01229 9.7e-180 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICOLMEJK_01230 5.3e-174 3.1.21.3 L N-6 DNA Methylase
ICOLMEJK_01231 3.4e-82 L Integrase
ICOLMEJK_01232 6.7e-131 S haloacid dehalogenase-like hydrolase
ICOLMEJK_01233 9.4e-63 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
ICOLMEJK_01234 1.1e-35 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
ICOLMEJK_01235 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
ICOLMEJK_01236 4.6e-85 L COG2801 Transposase and inactivated derivatives
ICOLMEJK_01237 4.2e-154 P CorA-like Mg2+ transporter protein
ICOLMEJK_01238 7.3e-110 IQ Enoyl-(Acyl carrier protein) reductase
ICOLMEJK_01239 5e-16
ICOLMEJK_01240 3.6e-39
ICOLMEJK_01241 1.6e-285 lacS G Transporter
ICOLMEJK_01242 1.6e-128 ltrA S Bacterial low temperature requirement A protein (LtrA)
ICOLMEJK_01243 3.3e-80 uspA T universal stress protein
ICOLMEJK_01244 5.6e-80 K AsnC family
ICOLMEJK_01245 4.4e-231 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ICOLMEJK_01246 1.9e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
ICOLMEJK_01247 3.8e-179 galR K Transcriptional regulator
ICOLMEJK_01248 2.5e-280 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
ICOLMEJK_01249 9.4e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ICOLMEJK_01250 8.4e-179 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
ICOLMEJK_01251 1.3e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
ICOLMEJK_01252 1.1e-92 yxkA S Phosphatidylethanolamine-binding protein
ICOLMEJK_01253 2.6e-35
ICOLMEJK_01255 7.1e-41 azlC E azaleucine resistance protein AzlC
ICOLMEJK_01256 8.9e-60 azlC E azaleucine resistance protein AzlC
ICOLMEJK_01257 4.2e-43 azlD E Branched-chain amino acid transport
ICOLMEJK_01258 6.2e-88 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
ICOLMEJK_01260 1.5e-97 S GyrI-like small molecule binding domain
ICOLMEJK_01261 2.7e-123 yhiD S MgtC family
ICOLMEJK_01262 1.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ICOLMEJK_01263 1.8e-87 V Beta-lactamase
ICOLMEJK_01264 4.8e-37 V Beta-lactamase
ICOLMEJK_01265 4.1e-36 V Beta-lactamase
ICOLMEJK_01266 8.2e-54 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
ICOLMEJK_01267 7.7e-88 XK27_08850 J Aminoacyl-tRNA editing domain
ICOLMEJK_01268 5.2e-19 relB L Addiction module antitoxin, RelB DinJ family
ICOLMEJK_01269 2.6e-23
ICOLMEJK_01270 2.4e-93 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
ICOLMEJK_01271 1.9e-113 T Transcriptional regulatory protein, C terminal
ICOLMEJK_01272 3.8e-214 T GHKL domain
ICOLMEJK_01273 2.8e-106 S Peptidase propeptide and YPEB domain
ICOLMEJK_01274 1.9e-76 P nitric oxide dioxygenase activity
ICOLMEJK_01275 1.7e-22 P FAD-binding domain
ICOLMEJK_01276 5.8e-09 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
ICOLMEJK_01277 5.2e-78 lytE M Lysin motif
ICOLMEJK_01278 1e-142 XK27_02985 S Cof-like hydrolase
ICOLMEJK_01279 1e-78 K Transcriptional regulator
ICOLMEJK_01280 0.0 oatA I Acyltransferase
ICOLMEJK_01281 6.9e-50
ICOLMEJK_01282 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ICOLMEJK_01283 1.2e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICOLMEJK_01284 2.9e-125 ybbR S YbbR-like protein
ICOLMEJK_01285 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ICOLMEJK_01286 4.8e-249 fucP G Major Facilitator Superfamily
ICOLMEJK_01287 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
ICOLMEJK_01288 2.9e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICOLMEJK_01289 2e-31 S Transglycosylase associated protein
ICOLMEJK_01291 2e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICOLMEJK_01292 4.2e-218 V domain protein
ICOLMEJK_01293 3.5e-94 K Transcriptional regulator (TetR family)
ICOLMEJK_01294 4.4e-39 pspC KT PspC domain protein
ICOLMEJK_01295 5.8e-152
ICOLMEJK_01296 4.1e-17 3.2.1.14 GH18
ICOLMEJK_01297 8.1e-81 zur P Belongs to the Fur family
ICOLMEJK_01298 2.8e-97 gmk2 2.7.4.8 F Guanylate kinase
ICOLMEJK_01299 9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
ICOLMEJK_01300 1.5e-253 yfnA E Amino Acid
ICOLMEJK_01301 5.3e-229 EGP Sugar (and other) transporter
ICOLMEJK_01302 4.9e-38
ICOLMEJK_01303 8.8e-35 yphJ 4.1.1.44 S decarboxylase
ICOLMEJK_01304 1.9e-83 C Flavodoxin
ICOLMEJK_01305 2.1e-149 K Transcriptional regulator
ICOLMEJK_01306 2.3e-53 lacA S transferase hexapeptide repeat
ICOLMEJK_01308 1.5e-142 S Alpha beta hydrolase
ICOLMEJK_01309 2.3e-153 tesE Q hydratase
ICOLMEJK_01310 3.8e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ICOLMEJK_01311 2.7e-227 aadAT EK Aminotransferase, class I
ICOLMEJK_01312 1.1e-154 ypuA S Protein of unknown function (DUF1002)
ICOLMEJK_01313 4.8e-182 ansA 3.5.1.1 EJ L-asparaginase, type I
ICOLMEJK_01314 3.7e-88 K Transcriptional regulator
ICOLMEJK_01315 3.4e-36 K Transcriptional regulator
ICOLMEJK_01316 2.1e-160 akr5f 1.1.1.346 S reductase
ICOLMEJK_01317 2.2e-63 yneR
ICOLMEJK_01318 1.1e-124 yfeJ 6.3.5.2 F glutamine amidotransferase
ICOLMEJK_01319 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ICOLMEJK_01320 4.2e-77 marR K Transcriptional regulator, MarR family
ICOLMEJK_01321 5.8e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICOLMEJK_01322 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICOLMEJK_01323 1.5e-159 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
ICOLMEJK_01324 3.6e-126 IQ reductase
ICOLMEJK_01325 4.1e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ICOLMEJK_01326 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ICOLMEJK_01327 3.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ICOLMEJK_01328 1e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
ICOLMEJK_01329 7.9e-141 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ICOLMEJK_01330 4.4e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
ICOLMEJK_01331 2e-127 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
ICOLMEJK_01340 1.2e-53
ICOLMEJK_01341 4.8e-114 frnE Q DSBA-like thioredoxin domain
ICOLMEJK_01342 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ICOLMEJK_01343 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
ICOLMEJK_01344 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ICOLMEJK_01345 2.8e-171 dnaI L Primosomal protein DnaI
ICOLMEJK_01346 1.4e-224 dnaB L replication initiation and membrane attachment
ICOLMEJK_01347 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ICOLMEJK_01348 1.3e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ICOLMEJK_01349 2.2e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ICOLMEJK_01350 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICOLMEJK_01351 1e-15 yoaK S Protein of unknown function (DUF1275)
ICOLMEJK_01352 3.1e-72 yoaK S Protein of unknown function (DUF1275)
ICOLMEJK_01353 1.4e-119 ybhL S Belongs to the BI1 family
ICOLMEJK_01354 1.3e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
ICOLMEJK_01355 4.2e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICOLMEJK_01358 6.4e-111 K Transcriptional regulator
ICOLMEJK_01359 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
ICOLMEJK_01360 2.4e-53 ysxB J Cysteine protease Prp
ICOLMEJK_01361 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
ICOLMEJK_01362 1.8e-130 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ICOLMEJK_01363 1.6e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ICOLMEJK_01364 9.7e-10 J 2'-5' RNA ligase superfamily
ICOLMEJK_01365 2.4e-90 J 2'-5' RNA ligase superfamily
ICOLMEJK_01366 2.2e-70 yqhY S Asp23 family, cell envelope-related function
ICOLMEJK_01367 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICOLMEJK_01368 3.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ICOLMEJK_01369 2.5e-234 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICOLMEJK_01370 9.6e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICOLMEJK_01371 2.5e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ICOLMEJK_01372 4.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
ICOLMEJK_01373 1.1e-77 argR K Regulates arginine biosynthesis genes
ICOLMEJK_01374 2e-260 recN L May be involved in recombinational repair of damaged DNA
ICOLMEJK_01375 5.4e-53
ICOLMEJK_01376 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
ICOLMEJK_01377 1e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ICOLMEJK_01378 3.2e-212 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ICOLMEJK_01379 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICOLMEJK_01380 4.8e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICOLMEJK_01381 8.2e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICOLMEJK_01382 7.2e-130 stp 3.1.3.16 T phosphatase
ICOLMEJK_01383 0.0 KLT serine threonine protein kinase
ICOLMEJK_01384 9.4e-161 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ICOLMEJK_01385 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
ICOLMEJK_01386 1.4e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
ICOLMEJK_01387 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
ICOLMEJK_01388 4.7e-58 asp S Asp23 family, cell envelope-related function
ICOLMEJK_01389 0.0 yloV S DAK2 domain fusion protein YloV
ICOLMEJK_01390 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICOLMEJK_01391 6.8e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ICOLMEJK_01392 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICOLMEJK_01393 9.5e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ICOLMEJK_01394 0.0 smc D Required for chromosome condensation and partitioning
ICOLMEJK_01395 2.5e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ICOLMEJK_01396 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ICOLMEJK_01397 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICOLMEJK_01398 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
ICOLMEJK_01399 4.1e-40 ylqC S Belongs to the UPF0109 family
ICOLMEJK_01400 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ICOLMEJK_01401 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
ICOLMEJK_01402 1.5e-261 yfnA E amino acid
ICOLMEJK_01403 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ICOLMEJK_01404 7.1e-53 S Mazg nucleotide pyrophosphohydrolase
ICOLMEJK_01405 4.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
ICOLMEJK_01406 2.3e-81
ICOLMEJK_01407 4.4e-186 lacR K Transcriptional regulator
ICOLMEJK_01408 0.0 lacS G Transporter
ICOLMEJK_01409 2.6e-70 lacZ 3.2.1.23 G -beta-galactosidase
ICOLMEJK_01410 7.3e-77 lacZ 3.2.1.23 G -beta-galactosidase
ICOLMEJK_01411 7.3e-189 lacZ 3.2.1.23 G -beta-galactosidase
ICOLMEJK_01412 3.9e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ICOLMEJK_01413 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
ICOLMEJK_01414 7.6e-116 S Domain of unknown function (DUF4811)
ICOLMEJK_01415 6.1e-253 lmrB EGP Major facilitator Superfamily
ICOLMEJK_01416 1.3e-73 merR K MerR HTH family regulatory protein
ICOLMEJK_01417 3.3e-53
ICOLMEJK_01418 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICOLMEJK_01419 2.3e-215 S CAAX protease self-immunity
ICOLMEJK_01420 4e-108 glnP P ABC transporter permease
ICOLMEJK_01421 3.2e-110 gluC P ABC transporter permease
ICOLMEJK_01422 3.7e-151 glnH ET ABC transporter
ICOLMEJK_01423 5.3e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICOLMEJK_01424 1.8e-81 usp1 T Belongs to the universal stress protein A family
ICOLMEJK_01425 1.1e-108 S VIT family
ICOLMEJK_01426 3e-114 S membrane
ICOLMEJK_01427 0.0 sbcC L Putative exonuclease SbcCD, C subunit
ICOLMEJK_01428 1.3e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
ICOLMEJK_01429 6.6e-178 M Glycosyl hydrolases family 25
ICOLMEJK_01430 3.5e-143 ywqE 3.1.3.48 GM PHP domain protein
ICOLMEJK_01431 0.0 snf 2.7.11.1 KL domain protein
ICOLMEJK_01434 7.1e-25
ICOLMEJK_01435 1.9e-99
ICOLMEJK_01436 6e-242
ICOLMEJK_01437 0.0
ICOLMEJK_01438 1e-177
ICOLMEJK_01439 6.8e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ICOLMEJK_01440 8.2e-102 fic D Fic/DOC family
ICOLMEJK_01441 5.6e-71
ICOLMEJK_01442 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
ICOLMEJK_01443 6.1e-91 L nuclease
ICOLMEJK_01445 5.1e-31
ICOLMEJK_01446 5.1e-43
ICOLMEJK_01447 2.4e-209 folP 2.5.1.15 H dihydropteroate synthase
ICOLMEJK_01448 7.2e-101 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
ICOLMEJK_01449 4.7e-222 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ICOLMEJK_01450 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
ICOLMEJK_01451 4.1e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
ICOLMEJK_01452 5.3e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICOLMEJK_01453 2.4e-68
ICOLMEJK_01454 6.9e-129 3.1.21.3 V Type I restriction modification DNA specificity domain
ICOLMEJK_01455 4.4e-240 bcgIA 2.1.1.72 V Type I restriction-modification system methyltransferase subunit()
ICOLMEJK_01456 1.9e-180 M Glycosyl hydrolases family 25
ICOLMEJK_01457 4.4e-48 S Bacteriophage holin of superfamily 6 (Holin_LLH)
ICOLMEJK_01458 2.5e-33
ICOLMEJK_01461 6.6e-09 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ICOLMEJK_01463 7.2e-19
ICOLMEJK_01464 1.4e-36 gp17a S Terminase-like family
ICOLMEJK_01465 1.6e-124 gp17a S Terminase-like family
ICOLMEJK_01466 9.1e-34
ICOLMEJK_01467 1.3e-51
ICOLMEJK_01469 7.4e-66
ICOLMEJK_01473 5.8e-146 tesE Q hydratase
ICOLMEJK_01474 7.5e-241 codA 3.5.4.1 F cytosine deaminase
ICOLMEJK_01475 4.4e-250 U Belongs to the purine-cytosine permease (2.A.39) family
ICOLMEJK_01476 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
ICOLMEJK_01477 2.8e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICOLMEJK_01478 6.5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ICOLMEJK_01480 1.6e-293 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICOLMEJK_01481 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
ICOLMEJK_01482 8.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICOLMEJK_01483 5.2e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ICOLMEJK_01484 1.3e-54 glsA 3.5.1.2 E Belongs to the glutaminase family
ICOLMEJK_01487 7.5e-27 4.6.1.1 T Pfam Adenylate and Guanylate cyclase catalytic domain
ICOLMEJK_01489 3.1e-56 tnp2PF3 L Transposase DDE domain
ICOLMEJK_01490 2.3e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
ICOLMEJK_01491 1.1e-113 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
ICOLMEJK_01492 4.2e-97 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
ICOLMEJK_01493 2.1e-46 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
ICOLMEJK_01494 5.1e-12 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ICOLMEJK_01495 2e-135 mleP S Membrane transport protein
ICOLMEJK_01496 1.2e-59 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
ICOLMEJK_01497 1.1e-72 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
ICOLMEJK_01498 1.8e-235 pbuG S permease
ICOLMEJK_01499 3.3e-258 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
ICOLMEJK_01500 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
ICOLMEJK_01501 2.5e-138 S Belongs to the UPF0246 family
ICOLMEJK_01502 9.4e-138 S Membrane
ICOLMEJK_01503 6.8e-74 4.4.1.5 E Glyoxalase
ICOLMEJK_01504 1.6e-21
ICOLMEJK_01505 7.4e-75 yueI S Protein of unknown function (DUF1694)
ICOLMEJK_01506 1.3e-240 rarA L recombination factor protein RarA
ICOLMEJK_01507 5.7e-46
ICOLMEJK_01508 4.3e-83 usp6 T universal stress protein
ICOLMEJK_01509 0.0 yjcE P Sodium proton antiporter
ICOLMEJK_01510 4.7e-52 yvlA
ICOLMEJK_01511 2.9e-111 P Cobalt transport protein
ICOLMEJK_01512 1.2e-242 cbiO1 S ABC transporter, ATP-binding protein
ICOLMEJK_01513 1e-96 S ABC-type cobalt transport system, permease component
ICOLMEJK_01514 3.6e-132 S membrane transporter protein
ICOLMEJK_01515 4.3e-138 IQ KR domain
ICOLMEJK_01516 9.5e-183 iunH2 3.2.2.1 F nucleoside hydrolase
ICOLMEJK_01517 3e-179 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
ICOLMEJK_01518 8.4e-49 S Double zinc ribbon
ICOLMEJK_01519 3.3e-13 S Double zinc ribbon
ICOLMEJK_01520 5e-83 T GHKL domain
ICOLMEJK_01521 3.2e-189 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICOLMEJK_01522 1e-307 lmrA V ABC transporter, ATP-binding protein
ICOLMEJK_01523 0.0 yfiC V ABC transporter
ICOLMEJK_01524 1.3e-281 pipD E Dipeptidase
ICOLMEJK_01525 1.5e-86 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ICOLMEJK_01526 1.6e-134 gntR K UbiC transcription regulator-associated domain protein
ICOLMEJK_01527 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
ICOLMEJK_01528 6.5e-222 cycA E Amino acid permease
ICOLMEJK_01529 6.7e-218 nupG F Nucleoside transporter
ICOLMEJK_01530 6e-171 rihC 3.2.2.1 F Nucleoside
ICOLMEJK_01531 7.7e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
ICOLMEJK_01532 1.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
ICOLMEJK_01533 2.7e-145 noc K Belongs to the ParB family
ICOLMEJK_01534 3.9e-139 soj D Sporulation initiation inhibitor
ICOLMEJK_01535 4.2e-153 spo0J K Belongs to the ParB family
ICOLMEJK_01536 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
ICOLMEJK_01537 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ICOLMEJK_01538 1.2e-132 XK27_01040 S Protein of unknown function (DUF1129)
ICOLMEJK_01539 5.7e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ICOLMEJK_01540 7e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
ICOLMEJK_01541 1.2e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
ICOLMEJK_01542 5.3e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
ICOLMEJK_01543 6.9e-170 deoR K sugar-binding domain protein
ICOLMEJK_01544 1.6e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ICOLMEJK_01545 3.8e-125 K response regulator
ICOLMEJK_01546 3.2e-201 hpk31 2.7.13.3 T Histidine kinase
ICOLMEJK_01547 3e-138 azlC E AzlC protein
ICOLMEJK_01548 6.2e-52 azlD S branched-chain amino acid
ICOLMEJK_01549 1.7e-125 K LysR substrate binding domain
ICOLMEJK_01550 3.3e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
ICOLMEJK_01551 9.3e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ICOLMEJK_01552 4e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ICOLMEJK_01553 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ICOLMEJK_01554 1.9e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ICOLMEJK_01555 2.1e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
ICOLMEJK_01556 1.5e-94 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ICOLMEJK_01557 7.2e-225 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
ICOLMEJK_01558 1.1e-173 K AI-2E family transporter
ICOLMEJK_01559 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
ICOLMEJK_01560 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
ICOLMEJK_01561 1.4e-130 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
ICOLMEJK_01562 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ICOLMEJK_01563 2.6e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ICOLMEJK_01564 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ICOLMEJK_01565 3.5e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
ICOLMEJK_01566 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICOLMEJK_01567 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICOLMEJK_01568 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICOLMEJK_01569 5e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ICOLMEJK_01570 4.3e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
ICOLMEJK_01571 3.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICOLMEJK_01572 2.6e-291 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
ICOLMEJK_01573 4.1e-242 purD 6.3.4.13 F Belongs to the GARS family
ICOLMEJK_01574 4.4e-67 L PFAM Integrase catalytic region
ICOLMEJK_01575 8.8e-176 pipD E Dipeptidase
ICOLMEJK_01576 6e-76 pipD E Dipeptidase
ICOLMEJK_01577 2.6e-197 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
ICOLMEJK_01579 5.2e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ICOLMEJK_01581 7.5e-58
ICOLMEJK_01582 4.8e-179 prmA J Ribosomal protein L11 methyltransferase
ICOLMEJK_01583 5.7e-127 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ICOLMEJK_01584 1.8e-51
ICOLMEJK_01585 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICOLMEJK_01586 1.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ICOLMEJK_01587 4.7e-154 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
ICOLMEJK_01588 2.5e-197 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ICOLMEJK_01589 2.7e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
ICOLMEJK_01590 3.2e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ICOLMEJK_01591 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ICOLMEJK_01593 8.3e-40 L PFAM Integrase catalytic region
ICOLMEJK_01594 2e-135 S Psort location CytoplasmicMembrane, score
ICOLMEJK_01595 4.5e-277 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
ICOLMEJK_01596 2.4e-139 IQ reductase
ICOLMEJK_01597 4e-52 yhaI S Protein of unknown function (DUF805)
ICOLMEJK_01598 2.2e-44
ICOLMEJK_01599 0.0 nylA 3.5.1.4 J Belongs to the amidase family
ICOLMEJK_01600 9.3e-47
ICOLMEJK_01601 1.9e-95 K Acetyltransferase (GNAT) domain
ICOLMEJK_01602 1e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
ICOLMEJK_01603 2e-40 gntT EG Gluconate
ICOLMEJK_01604 8.5e-24 gntT EG Gluconate
ICOLMEJK_01605 5.6e-133 gntT EG Gluconate
ICOLMEJK_01606 4.9e-111 lssY 3.6.1.27 I Acid phosphatase homologues
ICOLMEJK_01607 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
ICOLMEJK_01608 1.1e-228 clcA_2 P Chloride transporter, ClC family
ICOLMEJK_01609 3.9e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
ICOLMEJK_01610 1.9e-116 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ICOLMEJK_01611 1.1e-08 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ICOLMEJK_01612 2.6e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ICOLMEJK_01613 1.2e-51
ICOLMEJK_01614 0.0 S SEC-C Motif Domain Protein
ICOLMEJK_01617 1.1e-13 K Cro/C1-type HTH DNA-binding domain
ICOLMEJK_01619 8.3e-19
ICOLMEJK_01620 1.3e-263 dtpT U amino acid peptide transporter
ICOLMEJK_01621 4.8e-92 yjjH S Calcineurin-like phosphoesterase
ICOLMEJK_01622 2.3e-34 yjjH S Calcineurin-like phosphoesterase
ICOLMEJK_01625 8.5e-111
ICOLMEJK_01626 2.5e-248 EGP Major facilitator Superfamily
ICOLMEJK_01627 1.5e-300 aspT P Predicted Permease Membrane Region
ICOLMEJK_01628 1.9e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
ICOLMEJK_01629 4.5e-128 T Calcineurin-like phosphoesterase superfamily domain
ICOLMEJK_01630 4.2e-25
ICOLMEJK_01631 1.4e-61 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
ICOLMEJK_01632 1.6e-73 K Copper transport repressor CopY TcrY
ICOLMEJK_01633 0.0 copB 3.6.3.4 P P-type ATPase
ICOLMEJK_01634 1e-38 mdt(A) EGP Major facilitator Superfamily
ICOLMEJK_01636 2.1e-152 D CobQ CobB MinD ParA nucleotide binding domain protein
ICOLMEJK_01637 4.7e-45
ICOLMEJK_01638 5.4e-54 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
ICOLMEJK_01639 6e-149 2.3.1.19 K Helix-turn-helix XRE-family like proteins
ICOLMEJK_01640 6.5e-15 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
ICOLMEJK_01641 4.7e-227 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
ICOLMEJK_01642 2.2e-311 araB 2.7.1.16 G carbohydrate kinase FGGY
ICOLMEJK_01643 3.5e-134 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
ICOLMEJK_01644 6.4e-273 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
ICOLMEJK_01645 6.4e-94 maa 2.3.1.79 S Maltose O-acetyltransferase
ICOLMEJK_01646 2.4e-153 ytbE 1.1.1.346 S Aldo keto reductase
ICOLMEJK_01647 1e-204 araR K Transcriptional regulator
ICOLMEJK_01648 9.9e-291 clcA P chloride
ICOLMEJK_01649 1.8e-34 secG U Preprotein translocase
ICOLMEJK_01650 3.7e-145 est 3.1.1.1 S Serine aminopeptidase, S33
ICOLMEJK_01651 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ICOLMEJK_01652 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
ICOLMEJK_01653 1.7e-102 yxjI
ICOLMEJK_01654 2.4e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ICOLMEJK_01655 1.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
ICOLMEJK_01656 2.5e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
ICOLMEJK_01657 1.1e-84 K Acetyltransferase (GNAT) domain
ICOLMEJK_01658 3.8e-08 L Initiator Replication protein
ICOLMEJK_01660 8.5e-21 S Plasmid replication protein
ICOLMEJK_01661 9.8e-106 L Phage integrase family
ICOLMEJK_01662 6.2e-58 mobC S Bacterial mobilisation protein (MobC)
ICOLMEJK_01663 1.2e-198 D Relaxase/Mobilisation nuclease domain
ICOLMEJK_01664 6.9e-110
ICOLMEJK_01665 2.8e-29 XK27_09990 D Fic/DOC family
ICOLMEJK_01666 1.8e-19 XK27_09990 D Fic/DOC family
ICOLMEJK_01668 2.5e-158 L Lactococcus lactis RepB C-terminus
ICOLMEJK_01670 8.5e-67 S Protein of unknown function, DUF536
ICOLMEJK_01671 6.8e-225 sthIM 2.1.1.72 L DNA methylase
ICOLMEJK_01672 0.0 csd1 3.5.1.28 G domain, Protein
ICOLMEJK_01673 2.2e-162 yueF S AI-2E family transporter
ICOLMEJK_01674 1.2e-213 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ICOLMEJK_01675 1.7e-309 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ICOLMEJK_01676 2.5e-12 M NlpC/P60 family
ICOLMEJK_01677 0.0 M NlpC/P60 family
ICOLMEJK_01678 3.3e-158 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
ICOLMEJK_01680 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICOLMEJK_01681 5.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
ICOLMEJK_01682 9.7e-149 I Alpha beta
ICOLMEJK_01683 6.3e-16 I Alpha beta
ICOLMEJK_01684 2.1e-175 emrY EGP Major facilitator Superfamily
ICOLMEJK_01685 1.8e-116 ung2 3.2.2.27 L Uracil-DNA glycosylase
ICOLMEJK_01686 5.7e-250 yjjP S Putative threonine/serine exporter
ICOLMEJK_01687 2.2e-157 mleR K LysR family
ICOLMEJK_01688 9.4e-112 ydjP I Alpha/beta hydrolase family
ICOLMEJK_01689 1e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
ICOLMEJK_01690 2.7e-272 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
ICOLMEJK_01691 3.6e-160 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
ICOLMEJK_01692 8.5e-42 citD C Covalent carrier of the coenzyme of citrate lyase
ICOLMEJK_01693 7e-147 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ICOLMEJK_01694 2.5e-177 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
ICOLMEJK_01695 4e-125 citR K sugar-binding domain protein
ICOLMEJK_01696 1e-164 citP P Sodium:sulfate symporter transmembrane region
ICOLMEJK_01697 3.1e-130 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ICOLMEJK_01698 1.7e-265 frdC 1.3.5.4 C FAD binding domain
ICOLMEJK_01699 3.8e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
ICOLMEJK_01700 3.7e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
ICOLMEJK_01701 6.5e-154 mleR K LysR family
ICOLMEJK_01702 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICOLMEJK_01703 9.6e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
ICOLMEJK_01704 1.5e-294 L PFAM plasmid pRiA4b ORF-3 family protein
ICOLMEJK_01705 4.6e-263 S Uncharacterized protein conserved in bacteria (DUF2252)
ICOLMEJK_01708 5.8e-22
ICOLMEJK_01709 3.7e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
ICOLMEJK_01710 6.7e-75
ICOLMEJK_01711 3.6e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ICOLMEJK_01712 5e-129 ponA V Beta-lactamase enzyme family
ICOLMEJK_01713 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
ICOLMEJK_01714 2.2e-216 uhpT EGP Major facilitator Superfamily
ICOLMEJK_01715 3.9e-259 ytjP 3.5.1.18 E Dipeptidase
ICOLMEJK_01716 8.2e-274 arcD S C4-dicarboxylate anaerobic carrier
ICOLMEJK_01717 3e-181 yfeX P Peroxidase
ICOLMEJK_01718 2e-91 lsa S ABC transporter
ICOLMEJK_01719 1.5e-156 lsa S ABC transporter
ICOLMEJK_01720 1.3e-133 I alpha/beta hydrolase fold
ICOLMEJK_01721 4e-179 MA20_14895 S Conserved hypothetical protein 698
ICOLMEJK_01722 5.5e-110 dedA S SNARE-like domain protein
ICOLMEJK_01723 1e-103 S Protein of unknown function (DUF1461)
ICOLMEJK_01724 5.2e-131 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ICOLMEJK_01725 1.7e-93 yutD S Protein of unknown function (DUF1027)
ICOLMEJK_01726 1.7e-113 S Calcineurin-like phosphoesterase
ICOLMEJK_01727 1.5e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICOLMEJK_01728 3.9e-27 L PFAM transposase IS116 IS110 IS902
ICOLMEJK_01729 5.9e-45 L PFAM transposase IS116 IS110 IS902
ICOLMEJK_01730 1.9e-144 ytxK 2.1.1.72 L N-6 DNA Methylase
ICOLMEJK_01732 3.4e-71
ICOLMEJK_01733 4.2e-41
ICOLMEJK_01734 1.8e-130 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
ICOLMEJK_01735 1.3e-157
ICOLMEJK_01736 1.5e-155 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
ICOLMEJK_01737 4.9e-167 S AI-2E family transporter
ICOLMEJK_01738 5.5e-135 XK27_07210 6.1.1.6 S B3 4 domain
ICOLMEJK_01739 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
ICOLMEJK_01740 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
ICOLMEJK_01741 5.7e-89 GM epimerase
ICOLMEJK_01742 1.3e-154 ypdB V (ABC) transporter
ICOLMEJK_01743 9.5e-242 yhdP S Transporter associated domain
ICOLMEJK_01744 5.1e-09 L transposase, IS605 OrfB family
ICOLMEJK_01745 2.1e-60 L PFAM transposase IS200-family protein
ICOLMEJK_01746 2.3e-87 ywlG S Belongs to the UPF0340 family
ICOLMEJK_01747 2.1e-160 spoU 2.1.1.185 J Methyltransferase
ICOLMEJK_01748 4.1e-223 oxlT P Major Facilitator Superfamily
ICOLMEJK_01749 6.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
ICOLMEJK_01751 1.7e-218 S cog cog1373
ICOLMEJK_01752 1.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
ICOLMEJK_01753 3.1e-188 bacI V MacB-like periplasmic core domain
ICOLMEJK_01754 3.7e-128 V ABC transporter
ICOLMEJK_01755 5e-140 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICOLMEJK_01756 4.4e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
ICOLMEJK_01757 1.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICOLMEJK_01758 1.5e-146 E Glyoxalase-like domain
ICOLMEJK_01759 2.1e-224 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
ICOLMEJK_01760 2.2e-96 S reductase
ICOLMEJK_01761 0.0 trxB2 1.8.1.9 C Thioredoxin domain
ICOLMEJK_01762 7.9e-105 ahpC 1.11.1.15 O Peroxiredoxin
ICOLMEJK_01763 8.8e-143 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
ICOLMEJK_01764 2.9e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
ICOLMEJK_01766 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICOLMEJK_01767 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
ICOLMEJK_01768 2.4e-223 mdtG EGP Major facilitator Superfamily
ICOLMEJK_01769 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
ICOLMEJK_01770 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
ICOLMEJK_01771 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
ICOLMEJK_01772 7.6e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
ICOLMEJK_01773 4.3e-144 potB P ABC transporter permease
ICOLMEJK_01774 7.4e-136 potC P ABC transporter permease
ICOLMEJK_01775 1.6e-207 potD P ABC transporter
ICOLMEJK_01776 2.4e-50
ICOLMEJK_01777 3.5e-40
ICOLMEJK_01779 1.6e-154 KT YcbB domain
ICOLMEJK_01780 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ICOLMEJK_01781 2.1e-171 arcC 2.7.2.2 E Belongs to the carbamate kinase family
ICOLMEJK_01782 9.6e-161 EG EamA-like transporter family
ICOLMEJK_01783 1.9e-101 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
ICOLMEJK_01784 2.9e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
ICOLMEJK_01785 7e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
ICOLMEJK_01786 0.0 copA 3.6.3.54 P P-type ATPase
ICOLMEJK_01787 5.7e-172 scrR K Transcriptional regulator, LacI family
ICOLMEJK_01788 8.6e-24
ICOLMEJK_01789 9.6e-104
ICOLMEJK_01790 5.6e-217 yttB EGP Major facilitator Superfamily
ICOLMEJK_01791 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
ICOLMEJK_01792 3.1e-89
ICOLMEJK_01793 2.7e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
ICOLMEJK_01794 8.6e-176 S Putative peptidoglycan binding domain
ICOLMEJK_01795 1.7e-19 S Putative peptidoglycan binding domain
ICOLMEJK_01796 3.9e-195 lplA 6.3.1.20 H Lipoate-protein ligase
ICOLMEJK_01797 7.1e-63
ICOLMEJK_01798 5.2e-14
ICOLMEJK_01799 2.8e-107
ICOLMEJK_01800 5.2e-135 V ABC transporter
ICOLMEJK_01801 1.5e-211 EGP Major facilitator Superfamily
ICOLMEJK_01802 1e-254 G PTS system Galactitol-specific IIC component
ICOLMEJK_01803 7.2e-33 1.6.5.5 C Zinc-binding dehydrogenase
ICOLMEJK_01804 4.4e-33 1.6.5.5 C Zinc-binding dehydrogenase
ICOLMEJK_01805 3.7e-46
ICOLMEJK_01807 1.3e-87 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ICOLMEJK_01808 1.3e-205 amtB P ammonium transporter
ICOLMEJK_01809 6.4e-246 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
ICOLMEJK_01810 2.9e-20 S B3 4 domain
ICOLMEJK_01811 1.1e-90
ICOLMEJK_01812 1.2e-123 pnb C nitroreductase
ICOLMEJK_01813 3.1e-68 XK27_00915 C Luciferase-like monooxygenase
ICOLMEJK_01815 7.3e-95 mrr L restriction endonuclease
ICOLMEJK_01816 5.9e-08 mrr L Restriction endonuclease
ICOLMEJK_01820 4e-125 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
ICOLMEJK_01821 5.1e-169 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
ICOLMEJK_01823 4.2e-104 L Belongs to the 'phage' integrase family
ICOLMEJK_01824 3e-22 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
ICOLMEJK_01828 1.9e-46 L Transposase
ICOLMEJK_01829 3.4e-53 L Recombinase
ICOLMEJK_01830 3.2e-204
ICOLMEJK_01831 9.5e-261 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICOLMEJK_01832 3.9e-187 yegS 2.7.1.107 G Lipid kinase
ICOLMEJK_01833 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICOLMEJK_01834 5.9e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ICOLMEJK_01835 1.6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICOLMEJK_01836 3.6e-202 camS S sex pheromone
ICOLMEJK_01837 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICOLMEJK_01838 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
ICOLMEJK_01839 9.4e-214 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ICOLMEJK_01840 4.6e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ICOLMEJK_01841 2.3e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
ICOLMEJK_01842 3.6e-140 IQ reductase
ICOLMEJK_01843 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
ICOLMEJK_01844 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ICOLMEJK_01845 1.2e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ICOLMEJK_01846 1.2e-138 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICOLMEJK_01847 2.5e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICOLMEJK_01848 5.2e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICOLMEJK_01849 1.1e-62 rplQ J Ribosomal protein L17
ICOLMEJK_01850 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICOLMEJK_01851 1.2e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ICOLMEJK_01852 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ICOLMEJK_01853 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
ICOLMEJK_01854 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ICOLMEJK_01855 2.3e-124 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ICOLMEJK_01856 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ICOLMEJK_01857 8.9e-64 rplO J Binds to the 23S rRNA
ICOLMEJK_01858 2.9e-24 rpmD J Ribosomal protein L30
ICOLMEJK_01859 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ICOLMEJK_01860 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ICOLMEJK_01861 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ICOLMEJK_01862 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ICOLMEJK_01863 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICOLMEJK_01864 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ICOLMEJK_01865 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ICOLMEJK_01866 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ICOLMEJK_01867 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ICOLMEJK_01868 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
ICOLMEJK_01869 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ICOLMEJK_01870 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ICOLMEJK_01871 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ICOLMEJK_01872 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ICOLMEJK_01873 2.1e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ICOLMEJK_01874 1.7e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ICOLMEJK_01875 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
ICOLMEJK_01876 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ICOLMEJK_01877 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
ICOLMEJK_01878 6.3e-28 L Phage integrase family
ICOLMEJK_01881 9.6e-09 tnp L Lactococcus lactis RepB C-terminus
ICOLMEJK_01882 4.4e-80 L Initiator Replication protein
ICOLMEJK_01883 2.9e-11 S HTH domain
ICOLMEJK_01884 0.0 kup P Transport of potassium into the cell
ICOLMEJK_01885 5e-57
ICOLMEJK_01886 1.2e-10 S Protein of unknown function (DUF4044)
ICOLMEJK_01887 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
ICOLMEJK_01888 1.4e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ICOLMEJK_01889 4.2e-158 rrmA 2.1.1.187 H Methyltransferase
ICOLMEJK_01890 2.8e-180 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
ICOLMEJK_01891 1.7e-14 L Transposase
ICOLMEJK_01892 3.3e-149 L Transposase IS66 family
ICOLMEJK_01893 1.8e-206 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
ICOLMEJK_01894 0.0 clpL O associated with various cellular activities
ICOLMEJK_01895 7.8e-32
ICOLMEJK_01896 3.1e-215 patA 2.6.1.1 E Aminotransferase
ICOLMEJK_01897 2e-175 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICOLMEJK_01898 4.2e-74 osmC O OsmC-like protein
ICOLMEJK_01899 5.1e-81 uspA T universal stress protein
ICOLMEJK_01900 0.0 tetP J elongation factor G
ICOLMEJK_01901 3.5e-16 tetP J elongation factor G
ICOLMEJK_01902 9.9e-166 GK ROK family
ICOLMEJK_01903 1.1e-234 brnQ U Component of the transport system for branched-chain amino acids
ICOLMEJK_01904 2.1e-137 aroD S Serine hydrolase (FSH1)
ICOLMEJK_01905 6.3e-241 yagE E amino acid
ICOLMEJK_01906 1.7e-34 yaaA S S4 domain protein YaaA
ICOLMEJK_01907 5.5e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ICOLMEJK_01908 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICOLMEJK_01909 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICOLMEJK_01910 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
ICOLMEJK_01911 3.1e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ICOLMEJK_01912 4.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICOLMEJK_01913 3.7e-35 hxlR K regulation of RNA biosynthetic process
ICOLMEJK_01914 1.1e-164 G Belongs to the carbohydrate kinase PfkB family
ICOLMEJK_01915 1.4e-245 F Belongs to the purine-cytosine permease (2.A.39) family
ICOLMEJK_01916 2e-205 yegU O ADP-ribosylglycohydrolase
ICOLMEJK_01917 6.5e-47 pncA Q Isochorismatase family
ICOLMEJK_01918 1.6e-45 pncA Q Isochorismatase family
ICOLMEJK_01919 3.6e-271 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICOLMEJK_01920 2.2e-131 3.6.1.13, 3.6.1.55 F NUDIX domain
ICOLMEJK_01921 2.2e-54 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
ICOLMEJK_01922 1.2e-94 wecD3 K PFAM GCN5-related N-acetyltransferase
ICOLMEJK_01923 3.4e-99 ltrA S Bacterial low temperature requirement A protein (LtrA)
ICOLMEJK_01924 6.9e-204 cytX U Belongs to the purine-cytosine permease (2.A.39) family
ICOLMEJK_01925 4.3e-13
ICOLMEJK_01926 2.8e-66 S Domain of unknown function (DUF4767)
ICOLMEJK_01927 1.3e-136 L Transposase
ICOLMEJK_01928 9.7e-101 L Transposase
ICOLMEJK_01929 3e-57 K Transcriptional regulator, TetR family
ICOLMEJK_01931 1.7e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ICOLMEJK_01932 3.3e-85
ICOLMEJK_01933 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ICOLMEJK_01934 2.1e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ICOLMEJK_01935 6e-260 nox C NADH oxidase
ICOLMEJK_01936 3.1e-173 hoxN U High-affinity nickel-transport protein
ICOLMEJK_01937 2.6e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
ICOLMEJK_01938 1.8e-145 larE S NAD synthase
ICOLMEJK_01939 7.3e-228 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ICOLMEJK_01940 5.1e-131 cpmA S AIR carboxylase
ICOLMEJK_01941 6.4e-235 larA 5.1.2.1 S Domain of unknown function (DUF2088)
ICOLMEJK_01942 7.9e-123 K Crp-like helix-turn-helix domain
ICOLMEJK_01943 5.3e-169 yniA G Phosphotransferase enzyme family
ICOLMEJK_01944 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
ICOLMEJK_01945 2.9e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICOLMEJK_01946 5.3e-265 glnPH2 P ABC transporter permease
ICOLMEJK_01947 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
ICOLMEJK_01948 6.6e-70 yqeY S YqeY-like protein
ICOLMEJK_01949 8.8e-83 S Bacterial membrane protein, YfhO
ICOLMEJK_01950 3.9e-25
ICOLMEJK_01951 8.2e-89 S Glycosyltransferase like family
ICOLMEJK_01952 1e-86 M Domain of unknown function (DUF4422)
ICOLMEJK_01953 4.1e-41 M biosynthesis protein
ICOLMEJK_01954 5e-93 cps3F
ICOLMEJK_01955 3.2e-103 M Glycosyltransferase like family 2
ICOLMEJK_01956 1e-92 S Glycosyltransferase like family 2
ICOLMEJK_01957 1.1e-74 rgpB GT2 M Glycosyl transferase family 2
ICOLMEJK_01958 4.8e-215 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
ICOLMEJK_01959 1.4e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
ICOLMEJK_01960 1.4e-47 ganB 3.2.1.89 G arabinogalactan
ICOLMEJK_01961 0.0 ganB 3.2.1.89 G arabinogalactan
ICOLMEJK_01962 1.1e-83 ganB 3.2.1.89 G arabinogalactan
ICOLMEJK_01963 1e-287 3.5.1.28 M Ami_3
ICOLMEJK_01965 2.1e-25
ICOLMEJK_01966 0.0 G Peptidase_C39 like family
ICOLMEJK_01967 0.0 2.7.7.6 M Peptidase family M23
ICOLMEJK_01968 2.9e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
ICOLMEJK_01969 6.3e-176 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
ICOLMEJK_01970 2.7e-148 cps1D M Domain of unknown function (DUF4422)
ICOLMEJK_01971 9e-139 recX 2.4.1.337 GT4 S Regulatory protein RecX
ICOLMEJK_01972 2.2e-31
ICOLMEJK_01973 6.6e-34 S Protein of unknown function (DUF2922)
ICOLMEJK_01974 1.6e-152 yihY S Belongs to the UPF0761 family
ICOLMEJK_01975 6.9e-281 yjeM E Amino Acid
ICOLMEJK_01976 8.6e-257 E Arginine ornithine antiporter
ICOLMEJK_01977 1.3e-220 arcT 2.6.1.1 E Aminotransferase
ICOLMEJK_01978 5.5e-166 map 3.4.11.18 E Methionine Aminopeptidase
ICOLMEJK_01979 1.4e-78 fld C Flavodoxin
ICOLMEJK_01980 2.5e-74 gtcA S Teichoic acid glycosylation protein
ICOLMEJK_01981 7.9e-205 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ICOLMEJK_01983 2.4e-229 yfmL L DEAD DEAH box helicase
ICOLMEJK_01984 4.5e-191 mocA S Oxidoreductase
ICOLMEJK_01985 9.1e-62 S Domain of unknown function (DUF4828)
ICOLMEJK_01986 1.3e-107 yvdD 3.2.2.10 S Belongs to the LOG family
ICOLMEJK_01987 1.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ICOLMEJK_01988 3.1e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
ICOLMEJK_01989 3e-195 S Protein of unknown function (DUF3114)
ICOLMEJK_01990 2.7e-79 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
ICOLMEJK_01991 3.5e-118 ybhL S Belongs to the BI1 family
ICOLMEJK_01992 6.7e-78 yhjX P Major Facilitator Superfamily
ICOLMEJK_01993 7.1e-21
ICOLMEJK_01994 5.8e-291 mco Q Multicopper oxidase
ICOLMEJK_01995 2.9e-12 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
ICOLMEJK_01996 1.4e-189 yxaB GM Polysaccharide pyruvyl transferase
ICOLMEJK_01997 2.4e-117 L Transposase and inactivated derivatives, IS30 family
ICOLMEJK_01998 1e-162 gpG
ICOLMEJK_01999 9.1e-73 S Domain of unknown function (DUF4355)
ICOLMEJK_02000 1.2e-12
ICOLMEJK_02001 1.8e-95 yqeG S HAD phosphatase, family IIIA
ICOLMEJK_02002 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
ICOLMEJK_02003 5.4e-47 yhbY J RNA-binding protein
ICOLMEJK_02004 7.6e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ICOLMEJK_02005 2.3e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
ICOLMEJK_02006 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ICOLMEJK_02007 5.1e-136 yqeM Q Methyltransferase
ICOLMEJK_02008 3.4e-208 ylbM S Belongs to the UPF0348 family
ICOLMEJK_02009 5.4e-98 yceD S Uncharacterized ACR, COG1399
ICOLMEJK_02010 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
ICOLMEJK_02011 5.5e-217 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
ICOLMEJK_02012 3.9e-12
ICOLMEJK_02013 6.6e-151 P Belongs to the nlpA lipoprotein family
ICOLMEJK_02014 2.1e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICOLMEJK_02015 1.4e-50 S Iron-sulfur cluster assembly protein
ICOLMEJK_02016 8.8e-151
ICOLMEJK_02017 5e-182
ICOLMEJK_02018 1.3e-87 dut S Protein conserved in bacteria
ICOLMEJK_02020 9.6e-85 ydcK S Belongs to the SprT family
ICOLMEJK_02021 0.0 yhgF K Tex-like protein N-terminal domain protein
ICOLMEJK_02022 1.7e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ICOLMEJK_02023 7.7e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICOLMEJK_02024 4.1e-127 gntR1 K UbiC transcription regulator-associated domain protein
ICOLMEJK_02025 1.4e-10
ICOLMEJK_02026 1.2e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICOLMEJK_02027 2.5e-126 3.1.3.73 G phosphoglycerate mutase
ICOLMEJK_02028 9.7e-115 dedA S SNARE associated Golgi protein
ICOLMEJK_02029 0.0 helD 3.6.4.12 L DNA helicase
ICOLMEJK_02030 6.6e-153 vicX 3.1.26.11 S domain protein
ICOLMEJK_02031 9.3e-150 yycI S YycH protein
ICOLMEJK_02032 2.5e-247 yycH S YycH protein
ICOLMEJK_02033 0.0 vicK 2.7.13.3 T Histidine kinase
ICOLMEJK_02034 3.1e-130 K response regulator
ICOLMEJK_02036 5.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ICOLMEJK_02037 8.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ICOLMEJK_02038 1.7e-191 yeaN P Transporter, major facilitator family protein
ICOLMEJK_02039 1.3e-72 S 3-demethylubiquinone-9 3-methyltransferase
ICOLMEJK_02040 9.9e-85 nrdI F Belongs to the NrdI family
ICOLMEJK_02041 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ICOLMEJK_02042 8.6e-159 EG EamA-like transporter family
ICOLMEJK_02043 8.1e-171 nox C NADH oxidase
ICOLMEJK_02044 4e-26 nox C NADH oxidase
ICOLMEJK_02045 1.9e-142 nox C NADH oxidase
ICOLMEJK_02046 2.5e-39 nox C NADH oxidase
ICOLMEJK_02047 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICOLMEJK_02048 5.2e-265 glnP P ABC transporter
ICOLMEJK_02049 3.6e-249 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ICOLMEJK_02050 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
ICOLMEJK_02051 3.2e-142 S Abortive infection C-terminus
ICOLMEJK_02052 1.6e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
ICOLMEJK_02053 8e-42 S RelB antitoxin
ICOLMEJK_02054 3.4e-106 L Phage integrase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)