ORF_ID e_value Gene_name EC_number CAZy COGs Description
EKFNCIHE_00001 2.3e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EKFNCIHE_00003 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EKFNCIHE_00004 2.4e-33 yaaA S S4 domain
EKFNCIHE_00005 1.6e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EKFNCIHE_00006 8.1e-38 yaaB S Domain of unknown function (DUF370)
EKFNCIHE_00007 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKFNCIHE_00008 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKFNCIHE_00009 3.4e-39 S COG NOG14552 non supervised orthologous group
EKFNCIHE_00012 5.3e-181 yaaC S YaaC-like Protein
EKFNCIHE_00013 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EKFNCIHE_00014 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EKFNCIHE_00015 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EKFNCIHE_00016 2.8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EKFNCIHE_00017 1.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EKFNCIHE_00018 6.6e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EKFNCIHE_00019 1.3e-09
EKFNCIHE_00020 4.5e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
EKFNCIHE_00021 6.1e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
EKFNCIHE_00022 1.7e-211 yaaH M Glycoside Hydrolase Family
EKFNCIHE_00023 1.6e-97 yaaI Q COG1335 Amidases related to nicotinamidase
EKFNCIHE_00024 1.7e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EKFNCIHE_00025 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EKFNCIHE_00026 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EKFNCIHE_00027 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EKFNCIHE_00028 3.6e-32 yaaL S Protein of unknown function (DUF2508)
EKFNCIHE_00029 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
EKFNCIHE_00030 3.4e-39 S COG NOG14552 non supervised orthologous group
EKFNCIHE_00033 3.8e-30 csfB S Inhibitor of sigma-G Gin
EKFNCIHE_00034 3.3e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
EKFNCIHE_00035 1.4e-188 yaaN P Belongs to the TelA family
EKFNCIHE_00036 2.9e-268 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
EKFNCIHE_00037 1.3e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EKFNCIHE_00038 7.5e-55 yaaQ S protein conserved in bacteria
EKFNCIHE_00039 1.2e-71 yaaR S protein conserved in bacteria
EKFNCIHE_00040 1.3e-182 holB 2.7.7.7 L DNA polymerase III
EKFNCIHE_00041 8.8e-145 yaaT S stage 0 sporulation protein
EKFNCIHE_00042 7.7e-37 yabA L Involved in initiation control of chromosome replication
EKFNCIHE_00043 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
EKFNCIHE_00044 5.2e-47 yazA L endonuclease containing a URI domain
EKFNCIHE_00045 1.4e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EKFNCIHE_00046 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
EKFNCIHE_00047 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EKFNCIHE_00048 4.5e-143 tatD L hydrolase, TatD
EKFNCIHE_00049 7.7e-231 rpfB GH23 T protein conserved in bacteria
EKFNCIHE_00050 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EKFNCIHE_00051 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EKFNCIHE_00052 8.4e-146 yabG S peptidase
EKFNCIHE_00053 7.8e-39 veg S protein conserved in bacteria
EKFNCIHE_00054 2.9e-27 sspF S DNA topological change
EKFNCIHE_00055 3.5e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EKFNCIHE_00056 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
EKFNCIHE_00057 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
EKFNCIHE_00058 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EKFNCIHE_00059 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EKFNCIHE_00060 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EKFNCIHE_00061 3.8e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EKFNCIHE_00062 2.7e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EKFNCIHE_00063 3.7e-40 yabK S Peptide ABC transporter permease
EKFNCIHE_00064 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EKFNCIHE_00065 6.2e-91 spoVT K stage V sporulation protein
EKFNCIHE_00066 1.3e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKFNCIHE_00067 1.8e-273 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EKFNCIHE_00068 2.8e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EKFNCIHE_00069 1.9e-49 yabP S Sporulation protein YabP
EKFNCIHE_00070 8.4e-103 yabQ S spore cortex biosynthesis protein
EKFNCIHE_00071 4.1e-57 divIC D Septum formation initiator
EKFNCIHE_00072 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
EKFNCIHE_00075 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
EKFNCIHE_00076 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
EKFNCIHE_00077 1.4e-184 KLT serine threonine protein kinase
EKFNCIHE_00078 1.2e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EKFNCIHE_00079 1.5e-92 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EKFNCIHE_00080 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EKFNCIHE_00081 7.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EKFNCIHE_00082 2.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EKFNCIHE_00083 3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
EKFNCIHE_00084 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EKFNCIHE_00085 2.3e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EKFNCIHE_00086 2.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
EKFNCIHE_00087 5.5e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
EKFNCIHE_00088 9.4e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EKFNCIHE_00089 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EKFNCIHE_00090 2.4e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EKFNCIHE_00091 4.5e-29 yazB K transcriptional
EKFNCIHE_00092 7.8e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EKFNCIHE_00093 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EKFNCIHE_00094 3.4e-39 S COG NOG14552 non supervised orthologous group
EKFNCIHE_00096 1.3e-07
EKFNCIHE_00099 2e-08
EKFNCIHE_00104 3.4e-39 S COG NOG14552 non supervised orthologous group
EKFNCIHE_00105 7.5e-77 ctsR K Belongs to the CtsR family
EKFNCIHE_00106 6e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
EKFNCIHE_00107 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EKFNCIHE_00108 0.0 clpC O Belongs to the ClpA ClpB family
EKFNCIHE_00109 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EKFNCIHE_00110 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EKFNCIHE_00111 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
EKFNCIHE_00112 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EKFNCIHE_00113 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EKFNCIHE_00114 5.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EKFNCIHE_00115 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
EKFNCIHE_00116 6.2e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EKFNCIHE_00117 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EKFNCIHE_00118 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKFNCIHE_00119 4.2e-89 yacP S RNA-binding protein containing a PIN domain
EKFNCIHE_00120 8.9e-116 sigH K Belongs to the sigma-70 factor family
EKFNCIHE_00121 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EKFNCIHE_00122 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
EKFNCIHE_00123 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EKFNCIHE_00124 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EKFNCIHE_00125 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EKFNCIHE_00126 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EKFNCIHE_00127 1.8e-107 rsmC 2.1.1.172 J Methyltransferase
EKFNCIHE_00128 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKFNCIHE_00129 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKFNCIHE_00130 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
EKFNCIHE_00131 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EKFNCIHE_00132 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EKFNCIHE_00133 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EKFNCIHE_00134 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EKFNCIHE_00135 1.2e-182 ybaC 3.4.11.5 S Alpha/beta hydrolase family
EKFNCIHE_00136 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
EKFNCIHE_00137 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EKFNCIHE_00138 3e-105 rplD J Forms part of the polypeptide exit tunnel
EKFNCIHE_00139 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EKFNCIHE_00140 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EKFNCIHE_00141 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EKFNCIHE_00142 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EKFNCIHE_00143 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EKFNCIHE_00144 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EKFNCIHE_00145 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
EKFNCIHE_00146 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EKFNCIHE_00147 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EKFNCIHE_00148 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EKFNCIHE_00149 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EKFNCIHE_00150 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EKFNCIHE_00151 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EKFNCIHE_00152 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EKFNCIHE_00153 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EKFNCIHE_00154 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EKFNCIHE_00155 1.9e-23 rpmD J Ribosomal protein L30
EKFNCIHE_00156 4.1e-72 rplO J binds to the 23S rRNA
EKFNCIHE_00157 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EKFNCIHE_00158 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EKFNCIHE_00159 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
EKFNCIHE_00160 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EKFNCIHE_00161 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EKFNCIHE_00162 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EKFNCIHE_00163 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EKFNCIHE_00164 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKFNCIHE_00165 4.7e-58 rplQ J Ribosomal protein L17
EKFNCIHE_00166 5.6e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKFNCIHE_00167 9.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKFNCIHE_00168 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKFNCIHE_00169 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EKFNCIHE_00170 1.9e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EKFNCIHE_00171 6.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
EKFNCIHE_00172 4.5e-143 ybaJ Q Methyltransferase domain
EKFNCIHE_00173 1.2e-82 yizA S Damage-inducible protein DinB
EKFNCIHE_00174 1.4e-77 ybaK S Protein of unknown function (DUF2521)
EKFNCIHE_00175 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EKFNCIHE_00176 8.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EKFNCIHE_00177 1.7e-75 gerD
EKFNCIHE_00178 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
EKFNCIHE_00179 6e-132 pdaB 3.5.1.104 G Polysaccharide deacetylase
EKFNCIHE_00180 3.4e-39 S COG NOG14552 non supervised orthologous group
EKFNCIHE_00183 1.6e-08
EKFNCIHE_00186 3.4e-39 S COG NOG14552 non supervised orthologous group
EKFNCIHE_00187 9.4e-220 glcP G Major Facilitator Superfamily
EKFNCIHE_00188 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EKFNCIHE_00189 2.2e-176 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
EKFNCIHE_00190 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
EKFNCIHE_00191 3.5e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
EKFNCIHE_00192 9.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
EKFNCIHE_00193 1.9e-109 ybbA S Putative esterase
EKFNCIHE_00194 1.8e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFNCIHE_00195 8.1e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFNCIHE_00196 1.7e-171 feuA P Iron-uptake system-binding protein
EKFNCIHE_00197 2.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
EKFNCIHE_00198 3.3e-236 ybbC 3.2.1.52 S protein conserved in bacteria
EKFNCIHE_00199 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
EKFNCIHE_00200 5.2e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
EKFNCIHE_00201 8e-236 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EKFNCIHE_00202 2.9e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EKFNCIHE_00203 7.7e-85 ybbJ J acetyltransferase
EKFNCIHE_00204 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
EKFNCIHE_00210 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
EKFNCIHE_00211 2.9e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EKFNCIHE_00212 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EKFNCIHE_00213 1.5e-221 ybbR S protein conserved in bacteria
EKFNCIHE_00214 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EKFNCIHE_00215 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EKFNCIHE_00216 1.1e-153 V ATPases associated with a variety of cellular activities
EKFNCIHE_00217 3.7e-106 S ABC-2 family transporter protein
EKFNCIHE_00218 4.7e-99 ybdN
EKFNCIHE_00219 2.1e-131 ybdO S Domain of unknown function (DUF4885)
EKFNCIHE_00220 8.1e-162 dkgB S Aldo/keto reductase family
EKFNCIHE_00221 2.9e-93 yxaC M effector of murein hydrolase
EKFNCIHE_00222 6.9e-52 S LrgA family
EKFNCIHE_00223 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
EKFNCIHE_00224 2e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
EKFNCIHE_00225 3.3e-92 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EKFNCIHE_00226 1.6e-104 T Histidine kinase
EKFNCIHE_00227 3.8e-82 KT helix_turn_helix, Lux Regulon
EKFNCIHE_00228 3.5e-134 V ABC transporter, ATP-binding protein
EKFNCIHE_00229 6.8e-146 V ABC-2 type transporter
EKFNCIHE_00230 6e-123 V ABC-2 type transporter
EKFNCIHE_00231 4.4e-14
EKFNCIHE_00232 1.1e-58 bacT Q Thioesterase domain
EKFNCIHE_00233 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
EKFNCIHE_00234 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
EKFNCIHE_00235 6.7e-120 fabD 2.3.1.39 I PFAM Acyl transferase
EKFNCIHE_00236 0.0 Q Beta-ketoacyl synthase
EKFNCIHE_00237 0.0 Q Polyketide synthase modules and related proteins
EKFNCIHE_00238 1.2e-102 Q Flavin containing amine oxidoreductase
EKFNCIHE_00239 0.0 Q TIGRFAM amino acid adenylation domain
EKFNCIHE_00240 6.1e-50 crtF 2.1.1.210 Q PFAM O-methyltransferase
EKFNCIHE_00241 2.5e-75 S Domain of unknown function (DUF4879)
EKFNCIHE_00242 8.3e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
EKFNCIHE_00243 8e-107 yqeB
EKFNCIHE_00244 9.2e-40 ybyB
EKFNCIHE_00245 1.2e-291 ybeC E amino acid
EKFNCIHE_00246 3.7e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EKFNCIHE_00247 1.7e-259 glpT G -transporter
EKFNCIHE_00248 1e-16 S Protein of unknown function (DUF2651)
EKFNCIHE_00249 3.3e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
EKFNCIHE_00251 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
EKFNCIHE_00252 2e-31
EKFNCIHE_00253 1.2e-82 K Helix-turn-helix XRE-family like proteins
EKFNCIHE_00254 2.7e-194 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
EKFNCIHE_00255 1.2e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EKFNCIHE_00256 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EKFNCIHE_00257 1.9e-86 ybfM S SNARE associated Golgi protein
EKFNCIHE_00258 4.7e-151 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EKFNCIHE_00259 3.9e-41 ybfN
EKFNCIHE_00260 2.5e-191 yceA S Belongs to the UPF0176 family
EKFNCIHE_00261 2.5e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKFNCIHE_00262 9.5e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EKFNCIHE_00263 1.5e-256 mmuP E amino acid
EKFNCIHE_00264 8.7e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
EKFNCIHE_00265 2.7e-258 agcS E Sodium alanine symporter
EKFNCIHE_00266 5.9e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
EKFNCIHE_00267 1.1e-205 phoQ 2.7.13.3 T Histidine kinase
EKFNCIHE_00268 6.3e-171 glnL T Regulator
EKFNCIHE_00269 1.3e-125 ycbJ S Macrolide 2'-phosphotransferase
EKFNCIHE_00270 1.2e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
EKFNCIHE_00271 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKFNCIHE_00272 2.2e-108 ydfN C nitroreductase
EKFNCIHE_00273 2.2e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
EKFNCIHE_00274 1.5e-62 mhqP S DoxX
EKFNCIHE_00275 1.2e-55 traF CO Thioredoxin
EKFNCIHE_00276 5.6e-62 ycbP S Protein of unknown function (DUF2512)
EKFNCIHE_00277 5.3e-77 sleB 3.5.1.28 M Cell wall
EKFNCIHE_00278 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
EKFNCIHE_00279 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EKFNCIHE_00280 3.2e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKFNCIHE_00281 7.2e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EKFNCIHE_00282 2.3e-204 ycbU E Selenocysteine lyase
EKFNCIHE_00283 3e-241 lmrB EGP the major facilitator superfamily
EKFNCIHE_00284 1e-99 yxaF K Transcriptional regulator
EKFNCIHE_00285 1.6e-194 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EKFNCIHE_00286 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
EKFNCIHE_00287 7e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
EKFNCIHE_00288 1.8e-170 yccK C Aldo keto reductase
EKFNCIHE_00289 1.5e-175 ycdA S Domain of unknown function (DUF5105)
EKFNCIHE_00290 1.3e-254 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
EKFNCIHE_00291 1.6e-265 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
EKFNCIHE_00292 6.4e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
EKFNCIHE_00293 1e-188 S response regulator aspartate phosphatase
EKFNCIHE_00294 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
EKFNCIHE_00295 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
EKFNCIHE_00296 6.7e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
EKFNCIHE_00297 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EKFNCIHE_00298 9.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EKFNCIHE_00299 2e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFNCIHE_00300 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
EKFNCIHE_00301 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
EKFNCIHE_00302 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
EKFNCIHE_00303 9.7e-138 terC P Protein of unknown function (DUF475)
EKFNCIHE_00304 0.0 yceG S Putative component of 'biosynthetic module'
EKFNCIHE_00305 2.3e-193 yceH P Belongs to the TelA family
EKFNCIHE_00306 1.1e-212 naiP P Uncharacterised MFS-type transporter YbfB
EKFNCIHE_00307 3.9e-229 proV 3.6.3.32 E glycine betaine
EKFNCIHE_00308 1.6e-138 opuAB P glycine betaine
EKFNCIHE_00309 2e-163 opuAC E glycine betaine
EKFNCIHE_00310 3.1e-209 amhX S amidohydrolase
EKFNCIHE_00311 2.5e-227 ycgA S Membrane
EKFNCIHE_00312 1.5e-80 ycgB
EKFNCIHE_00313 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
EKFNCIHE_00314 1.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EKFNCIHE_00315 8.1e-261 mdr EGP Major facilitator Superfamily
EKFNCIHE_00316 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
EKFNCIHE_00317 4.7e-114 ycgF E Lysine exporter protein LysE YggA
EKFNCIHE_00318 1.2e-151 yqcI S YqcI/YcgG family
EKFNCIHE_00319 5.4e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
EKFNCIHE_00320 7.6e-114 ycgI S Domain of unknown function (DUF1989)
EKFNCIHE_00321 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EKFNCIHE_00323 1.4e-107 tmrB S AAA domain
EKFNCIHE_00324 2.5e-141 4.2.1.118 G Xylose isomerase-like TIM barrel
EKFNCIHE_00325 1.8e-221 G COG0477 Permeases of the major facilitator superfamily
EKFNCIHE_00326 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EKFNCIHE_00327 6.5e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
EKFNCIHE_00328 8.9e-147 ycgL S Predicted nucleotidyltransferase
EKFNCIHE_00329 8.7e-170 ycgM E Proline dehydrogenase
EKFNCIHE_00330 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
EKFNCIHE_00331 5.8e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKFNCIHE_00332 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
EKFNCIHE_00333 4.9e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EKFNCIHE_00334 4.6e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
EKFNCIHE_00335 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
EKFNCIHE_00336 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EKFNCIHE_00337 1.7e-226 yciC S GTPases (G3E family)
EKFNCIHE_00338 1.4e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EKFNCIHE_00339 4.8e-73 yckC S membrane
EKFNCIHE_00340 1.3e-48 S Protein of unknown function (DUF2680)
EKFNCIHE_00341 1.5e-65 nin S Competence protein J (ComJ)
EKFNCIHE_00342 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
EKFNCIHE_00343 1.9e-82 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
EKFNCIHE_00344 2.4e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
EKFNCIHE_00345 2.6e-61 hxlR K transcriptional
EKFNCIHE_00346 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFNCIHE_00347 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFNCIHE_00348 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
EKFNCIHE_00349 3.4e-140 srfAD Q thioesterase
EKFNCIHE_00350 6.7e-248 bamJ E Aminotransferase class I and II
EKFNCIHE_00351 2.2e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
EKFNCIHE_00352 1.7e-108 yczE S membrane
EKFNCIHE_00353 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EKFNCIHE_00354 6.3e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
EKFNCIHE_00355 1.2e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
EKFNCIHE_00356 3.9e-159 bsdA K LysR substrate binding domain
EKFNCIHE_00357 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EKFNCIHE_00358 5.3e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EKFNCIHE_00359 1.7e-37 bsdD 4.1.1.61 S response to toxic substance
EKFNCIHE_00360 1.3e-76 yclD
EKFNCIHE_00361 1.2e-269 dtpT E amino acid peptide transporter
EKFNCIHE_00362 1.2e-276 yclG M Pectate lyase superfamily protein
EKFNCIHE_00364 7.8e-294 gerKA EG Spore germination protein
EKFNCIHE_00365 5.2e-234 gerKC S spore germination
EKFNCIHE_00366 2.5e-195 gerKB F Spore germination protein
EKFNCIHE_00367 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFNCIHE_00368 1.1e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKFNCIHE_00369 1.3e-140 yxeM M Belongs to the bacterial solute-binding protein 3 family
EKFNCIHE_00370 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
EKFNCIHE_00371 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
EKFNCIHE_00372 6.4e-218 yxeP 3.5.1.47 E hydrolase activity
EKFNCIHE_00373 1.9e-250 yxeQ S MmgE/PrpD family
EKFNCIHE_00374 1.6e-120 yclH P ABC transporter
EKFNCIHE_00375 1e-228 yclI V ABC transporter (permease) YclI
EKFNCIHE_00376 6.8e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFNCIHE_00377 4.1e-259 T PhoQ Sensor
EKFNCIHE_00378 9.5e-81 S aspartate phosphatase
EKFNCIHE_00380 4.5e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
EKFNCIHE_00381 1.2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFNCIHE_00382 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFNCIHE_00383 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
EKFNCIHE_00384 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
EKFNCIHE_00385 1.2e-245 ycnB EGP Major facilitator Superfamily
EKFNCIHE_00386 6.7e-151 ycnC K Transcriptional regulator
EKFNCIHE_00387 2e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
EKFNCIHE_00388 1e-44 ycnE S Monooxygenase
EKFNCIHE_00389 1.5e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
EKFNCIHE_00390 6.7e-262 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKFNCIHE_00391 2.1e-217 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EKFNCIHE_00392 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EKFNCIHE_00393 3.6e-149 glcU U Glucose uptake
EKFNCIHE_00394 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFNCIHE_00395 3.9e-97 ycnI S protein conserved in bacteria
EKFNCIHE_00396 2e-297 ycnJ P protein, homolog of Cu resistance protein CopC
EKFNCIHE_00397 5.6e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
EKFNCIHE_00398 1.6e-55
EKFNCIHE_00399 7.9e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
EKFNCIHE_00400 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EKFNCIHE_00401 1.3e-204 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
EKFNCIHE_00402 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
EKFNCIHE_00404 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EKFNCIHE_00405 1e-139 ycsF S Belongs to the UPF0271 (lamB) family
EKFNCIHE_00406 4.4e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
EKFNCIHE_00407 2.1e-148 ycsI S Belongs to the D-glutamate cyclase family
EKFNCIHE_00408 4.3e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
EKFNCIHE_00409 1.2e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
EKFNCIHE_00410 1.3e-129 kipR K Transcriptional regulator
EKFNCIHE_00411 1e-116 ycsK E anatomical structure formation involved in morphogenesis
EKFNCIHE_00413 5.1e-56 yczJ S biosynthesis
EKFNCIHE_00414 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
EKFNCIHE_00415 3.7e-173 ydhF S Oxidoreductase
EKFNCIHE_00416 0.0 mtlR K transcriptional regulator, MtlR
EKFNCIHE_00417 5.5e-286 ydaB IQ acyl-CoA ligase
EKFNCIHE_00418 2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFNCIHE_00419 1.1e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
EKFNCIHE_00420 5.5e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EKFNCIHE_00421 1.4e-77 ydaG 1.4.3.5 S general stress protein
EKFNCIHE_00422 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EKFNCIHE_00423 1.3e-47 ydzA EGP Major facilitator Superfamily
EKFNCIHE_00424 4.3e-74 lrpC K Transcriptional regulator
EKFNCIHE_00425 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EKFNCIHE_00426 2.8e-199 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
EKFNCIHE_00427 2.5e-147 ydaK T Diguanylate cyclase, GGDEF domain
EKFNCIHE_00428 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
EKFNCIHE_00429 7.2e-231 ydaM M Glycosyl transferase family group 2
EKFNCIHE_00430 0.0 ydaN S Bacterial cellulose synthase subunit
EKFNCIHE_00431 0.0 ydaO E amino acid
EKFNCIHE_00432 4.5e-71 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
EKFNCIHE_00433 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EKFNCIHE_00434 1.4e-12
EKFNCIHE_00436 3.1e-77
EKFNCIHE_00437 8.2e-97
EKFNCIHE_00438 1.8e-38
EKFNCIHE_00439 2.7e-225 mntH P H( )-stimulated, divalent metal cation uptake system
EKFNCIHE_00441 6.5e-34 ydaT
EKFNCIHE_00442 3.7e-72 yvaD S Family of unknown function (DUF5360)
EKFNCIHE_00443 4.6e-53 yvaE P Small Multidrug Resistance protein
EKFNCIHE_00444 1.7e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
EKFNCIHE_00446 3.4e-58 ydbB G Cupin domain
EKFNCIHE_00447 8.5e-60 ydbC S Domain of unknown function (DUF4937
EKFNCIHE_00448 1.2e-154 ydbD P Catalase
EKFNCIHE_00449 1.9e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EKFNCIHE_00450 3.6e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EKFNCIHE_00451 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
EKFNCIHE_00452 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKFNCIHE_00453 4e-158 ydbI S AI-2E family transporter
EKFNCIHE_00454 2.3e-170 ydbJ V ABC transporter, ATP-binding protein
EKFNCIHE_00455 2.2e-129 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EKFNCIHE_00456 4.6e-52 ydbL
EKFNCIHE_00457 3e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
EKFNCIHE_00458 1.5e-10 S Fur-regulated basic protein B
EKFNCIHE_00459 5.8e-09 S Fur-regulated basic protein A
EKFNCIHE_00460 3.4e-118 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKFNCIHE_00461 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EKFNCIHE_00462 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EKFNCIHE_00463 1e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EKFNCIHE_00464 1.4e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EKFNCIHE_00465 1.3e-60 ydbS S Bacterial PH domain
EKFNCIHE_00466 2.9e-260 ydbT S Membrane
EKFNCIHE_00467 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
EKFNCIHE_00468 6.8e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EKFNCIHE_00469 5.8e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
EKFNCIHE_00470 2.6e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EKFNCIHE_00471 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EKFNCIHE_00472 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
EKFNCIHE_00473 6.7e-145 rsbR T Positive regulator of sigma-B
EKFNCIHE_00474 1.8e-57 rsbS T antagonist
EKFNCIHE_00475 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EKFNCIHE_00476 1.7e-187 rsbU 3.1.3.3 KT phosphatase
EKFNCIHE_00477 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
EKFNCIHE_00478 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EKFNCIHE_00479 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFNCIHE_00480 1.8e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
EKFNCIHE_00481 0.0 yhgF K COG2183 Transcriptional accessory protein
EKFNCIHE_00482 1.7e-14
EKFNCIHE_00483 5.6e-58 ydcK S Belongs to the SprT family
EKFNCIHE_00491 1.1e-95 ywrO S Flavodoxin-like fold
EKFNCIHE_00492 6.8e-150 S Serine aminopeptidase, S33
EKFNCIHE_00493 5.7e-229 proP EGP Transporter
EKFNCIHE_00494 3.8e-136 I esterase
EKFNCIHE_00495 1.3e-46 ohrB O OsmC-like protein
EKFNCIHE_00496 1.4e-48 ohrR K Transcriptional regulator
EKFNCIHE_00497 1.7e-64 ywnA K Transcriptional regulator
EKFNCIHE_00498 5.4e-110 ywnB S NAD(P)H-binding
EKFNCIHE_00499 1.4e-30 cspL K Cold shock
EKFNCIHE_00500 6.8e-78 carD K Transcription factor
EKFNCIHE_00501 9.2e-40 yrkD S protein conserved in bacteria
EKFNCIHE_00502 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
EKFNCIHE_00503 2.2e-17 P Rhodanese Homology Domain
EKFNCIHE_00504 2.9e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
EKFNCIHE_00505 7.6e-200 yrkH P Rhodanese Homology Domain
EKFNCIHE_00506 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
EKFNCIHE_00507 1.5e-117 yrkJ S membrane transporter protein
EKFNCIHE_00508 5.8e-118 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EKFNCIHE_00509 1.1e-101 S Protein of unknown function (DUF2812)
EKFNCIHE_00510 2.4e-50 K Transcriptional regulator PadR-like family
EKFNCIHE_00511 5.2e-181 S Patatin-like phospholipase
EKFNCIHE_00512 2.7e-82 S DinB superfamily
EKFNCIHE_00513 4.7e-115 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
EKFNCIHE_00514 4.5e-67 K COG1802 Transcriptional regulators
EKFNCIHE_00515 1.7e-39 yabJ 3.5.99.10 J Endoribonuclease L-PSP
EKFNCIHE_00516 2.2e-142 sdaC E Serine transporter
EKFNCIHE_00517 5.3e-164 E Peptidase dimerisation domain
EKFNCIHE_00518 7.6e-126 rhaS5 K helix_turn_helix, arabinose operon control protein
EKFNCIHE_00519 3.2e-175 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EKFNCIHE_00520 6.5e-233 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKFNCIHE_00521 2.6e-191 ydeG EGP Major facilitator superfamily
EKFNCIHE_00522 3.5e-28 3.6.1.55 F Belongs to the Nudix hydrolase family
EKFNCIHE_00525 4.3e-266 ygaK C COG0277 FAD FMN-containing dehydrogenases
EKFNCIHE_00526 1.1e-167 czcD P COG1230 Co Zn Cd efflux system component
EKFNCIHE_00527 4e-195 trkA P Oxidoreductase
EKFNCIHE_00530 1.8e-14 ykkA S Protein of unknown function (DUF664)
EKFNCIHE_00531 5.1e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
EKFNCIHE_00533 6.9e-195 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
EKFNCIHE_00534 2.6e-51 ydeH
EKFNCIHE_00535 2e-164 S Sodium Bile acid symporter family
EKFNCIHE_00536 4.2e-200 adhA 1.1.1.1 C alcohol dehydrogenase
EKFNCIHE_00537 1.8e-66 yraB K helix_turn_helix, mercury resistance
EKFNCIHE_00538 2.3e-224 mleN_2 C antiporter
EKFNCIHE_00539 6e-255 K helix_turn_helix gluconate operon transcriptional repressor
EKFNCIHE_00540 2.3e-113 paiB K Transcriptional regulator
EKFNCIHE_00542 1.9e-177 ydeR EGP Major facilitator Superfamily
EKFNCIHE_00543 1.6e-100 ydeS K Transcriptional regulator
EKFNCIHE_00544 1.4e-47 yraD M Spore coat protein
EKFNCIHE_00545 3.1e-24 yraE
EKFNCIHE_00546 1.5e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EKFNCIHE_00547 8.4e-63 yraF M Spore coat protein
EKFNCIHE_00548 1.3e-35 yraG
EKFNCIHE_00549 5.6e-215 ydfH 2.7.13.3 T Histidine kinase
EKFNCIHE_00550 6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFNCIHE_00551 0.0 ydfJ S drug exporters of the RND superfamily
EKFNCIHE_00552 6.7e-133 puuD S Peptidase C26
EKFNCIHE_00553 6.7e-298 expZ S ABC transporter
EKFNCIHE_00554 5.7e-97 ynaD J Acetyltransferase (GNAT) domain
EKFNCIHE_00555 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
EKFNCIHE_00556 2.7e-197 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
EKFNCIHE_00557 1.8e-210 tcaB EGP Major facilitator Superfamily
EKFNCIHE_00558 3.7e-224 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EKFNCIHE_00559 5e-156 K Helix-turn-helix XRE-family like proteins
EKFNCIHE_00560 9.4e-122 ydhB S membrane transporter protein
EKFNCIHE_00561 2.2e-81 bltD 2.3.1.57 K FR47-like protein
EKFNCIHE_00562 9e-150 bltR K helix_turn_helix, mercury resistance
EKFNCIHE_00563 1.1e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EKFNCIHE_00564 8.1e-111 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
EKFNCIHE_00565 2.4e-144 ycgJ_1 Q ubiE/COQ5 methyltransferase family
EKFNCIHE_00566 6.1e-167 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Isocitrate/isopropylmalate dehydrogenase
EKFNCIHE_00567 6.9e-119 ydhC K FCD
EKFNCIHE_00568 1e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EKFNCIHE_00571 1.1e-261 pbpE V Beta-lactamase
EKFNCIHE_00573 5.5e-98 ydhK M Protein of unknown function (DUF1541)
EKFNCIHE_00574 2e-195 pbuE EGP Major facilitator Superfamily
EKFNCIHE_00575 1.5e-132 ydhQ K UTRA
EKFNCIHE_00576 9.9e-118 K FCD
EKFNCIHE_00577 8.2e-216 yeaN P COG2807 Cyanate permease
EKFNCIHE_00578 2.6e-49 sugE P Small Multidrug Resistance protein
EKFNCIHE_00579 2.3e-51 ykkC P Small Multidrug Resistance protein
EKFNCIHE_00580 2.9e-102 yvdT K Transcriptional regulator
EKFNCIHE_00581 9.3e-297 yveA E amino acid
EKFNCIHE_00582 1.9e-163 ydhU P Catalase
EKFNCIHE_00583 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
EKFNCIHE_00584 7.5e-183 yhfP 1.1.1.1 C Quinone oxidoreductase
EKFNCIHE_00585 2.9e-249 iolT EGP Major facilitator Superfamily
EKFNCIHE_00588 3.4e-39 S COG NOG14552 non supervised orthologous group
EKFNCIHE_00589 7.8e-08
EKFNCIHE_00591 1.3e-182 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EKFNCIHE_00592 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
EKFNCIHE_00593 4.6e-123 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
EKFNCIHE_00594 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EKFNCIHE_00595 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EKFNCIHE_00596 0.0 ydiF S ABC transporter
EKFNCIHE_00597 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EKFNCIHE_00598 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EKFNCIHE_00599 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EKFNCIHE_00600 3.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKFNCIHE_00601 1.7e-27 ydiK S Domain of unknown function (DUF4305)
EKFNCIHE_00602 9.6e-127 ydiL S CAAX protease self-immunity
EKFNCIHE_00603 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EKFNCIHE_00604 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EKFNCIHE_00605 1.5e-24 S Protein of unknown function (DUF4064)
EKFNCIHE_00606 0.0 K NB-ARC domain
EKFNCIHE_00607 5e-201 gutB 1.1.1.14 E Dehydrogenase
EKFNCIHE_00608 1.4e-248 gutA G MFS/sugar transport protein
EKFNCIHE_00609 3.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
EKFNCIHE_00610 3.1e-29 yjdJ S Domain of unknown function (DUF4306)
EKFNCIHE_00611 1.3e-112 pspA KT Phage shock protein A
EKFNCIHE_00612 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EKFNCIHE_00613 2.9e-118 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
EKFNCIHE_00614 1.8e-144 ydjI S virion core protein (lumpy skin disease virus)
EKFNCIHE_00615 0.0 yrhL I Acyltransferase family
EKFNCIHE_00616 1.4e-145 rsiV S Protein of unknown function (DUF3298)
EKFNCIHE_00617 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
EKFNCIHE_00618 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
EKFNCIHE_00619 1.2e-61 ydjM M Lytic transglycolase
EKFNCIHE_00620 2e-133 ydjN U Involved in the tonB-independent uptake of proteins
EKFNCIHE_00622 7.2e-35 ydjO S Cold-inducible protein YdjO
EKFNCIHE_00623 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
EKFNCIHE_00624 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
EKFNCIHE_00625 2.1e-174 yeaC S COG0714 MoxR-like ATPases
EKFNCIHE_00626 1.1e-206 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EKFNCIHE_00627 0.0 yebA E COG1305 Transglutaminase-like enzymes
EKFNCIHE_00628 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EKFNCIHE_00629 5e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
EKFNCIHE_00630 1e-249 S Domain of unknown function (DUF4179)
EKFNCIHE_00631 8.1e-209 pbuG S permease
EKFNCIHE_00632 1.5e-125 yebC M Membrane
EKFNCIHE_00634 7.5e-92 yebE S UPF0316 protein
EKFNCIHE_00635 5.5e-29 yebG S NETI protein
EKFNCIHE_00636 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EKFNCIHE_00637 3e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EKFNCIHE_00638 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EKFNCIHE_00639 3.8e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EKFNCIHE_00640 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKFNCIHE_00641 1.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKFNCIHE_00642 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKFNCIHE_00643 1.2e-269 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EKFNCIHE_00644 1.9e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EKFNCIHE_00645 9.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EKFNCIHE_00646 5e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EKFNCIHE_00647 1.2e-233 purD 6.3.4.13 F Belongs to the GARS family
EKFNCIHE_00648 2.6e-25 S Protein of unknown function (DUF2892)
EKFNCIHE_00649 0.0 yerA 3.5.4.2 F adenine deaminase
EKFNCIHE_00650 1.5e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
EKFNCIHE_00651 2.4e-50 yerC S protein conserved in bacteria
EKFNCIHE_00652 7.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
EKFNCIHE_00653 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EKFNCIHE_00654 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EKFNCIHE_00655 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EKFNCIHE_00656 2e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
EKFNCIHE_00657 6.1e-193 yerI S homoserine kinase type II (protein kinase fold)
EKFNCIHE_00658 1.3e-120 sapB S MgtC SapB transporter
EKFNCIHE_00659 4.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKFNCIHE_00660 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKFNCIHE_00661 4.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EKFNCIHE_00662 3.4e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKFNCIHE_00663 1.9e-150 yerO K Transcriptional regulator
EKFNCIHE_00664 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EKFNCIHE_00665 6.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EKFNCIHE_00666 4.2e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EKFNCIHE_00667 4.5e-21
EKFNCIHE_00668 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
EKFNCIHE_00669 2.2e-138 cylB V ABC-2 type transporter
EKFNCIHE_00670 3.3e-37 S Protein of unknown function, DUF600
EKFNCIHE_00671 2.7e-85 S Protein of unknown function, DUF600
EKFNCIHE_00672 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
EKFNCIHE_00673 1.1e-20
EKFNCIHE_00674 9.4e-127 yeeN K transcriptional regulatory protein
EKFNCIHE_00676 9e-108 aadK G Streptomycin adenylyltransferase
EKFNCIHE_00677 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
EKFNCIHE_00678 1.3e-44 cotJB S CotJB protein
EKFNCIHE_00679 8.9e-104 cotJC P Spore Coat
EKFNCIHE_00680 2e-94 yesJ K Acetyltransferase (GNAT) family
EKFNCIHE_00682 7.4e-121 yetF S membrane
EKFNCIHE_00683 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
EKFNCIHE_00684 3.7e-63 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKFNCIHE_00685 3.7e-154 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EKFNCIHE_00686 3.4e-22 yezD S Uncharacterized small protein (DUF2292)
EKFNCIHE_00687 2.6e-54 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
EKFNCIHE_00688 2.4e-105 yetJ S Belongs to the BI1 family
EKFNCIHE_00690 8e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
EKFNCIHE_00691 4.3e-203 yetM CH FAD binding domain
EKFNCIHE_00692 3.4e-197 yetN S Protein of unknown function (DUF3900)
EKFNCIHE_00693 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
EKFNCIHE_00694 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EKFNCIHE_00695 1.8e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
EKFNCIHE_00696 2.4e-172 yfnG 4.2.1.45 M dehydratase
EKFNCIHE_00697 1.3e-178 yfnF M Nucleotide-diphospho-sugar transferase
EKFNCIHE_00698 9.9e-219 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
EKFNCIHE_00699 1.5e-185 yfnD M Nucleotide-diphospho-sugar transferase
EKFNCIHE_00700 1.4e-210 fsr P COG0477 Permeases of the major facilitator superfamily
EKFNCIHE_00701 3e-246 yfnA E amino acid
EKFNCIHE_00702 3.8e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EKFNCIHE_00703 7.5e-107 yfmS NT chemotaxis protein
EKFNCIHE_00704 5.8e-166 IQ Enoyl-(Acyl carrier protein) reductase
EKFNCIHE_00705 1.2e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EKFNCIHE_00706 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EKFNCIHE_00707 1.8e-69 yfmP K transcriptional
EKFNCIHE_00708 9.8e-206 yfmO EGP Major facilitator Superfamily
EKFNCIHE_00709 1.2e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EKFNCIHE_00710 1.7e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
EKFNCIHE_00711 2.1e-41 yfmK 2.3.1.128 K acetyltransferase
EKFNCIHE_00712 2.3e-187 yfmJ S N-terminal domain of oxidoreductase
EKFNCIHE_00713 2.7e-24 S Protein of unknown function (DUF3212)
EKFNCIHE_00714 1.3e-57 yflT S Heat induced stress protein YflT
EKFNCIHE_00715 1e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
EKFNCIHE_00716 6e-234 yflS P Sodium:sulfate symporter transmembrane region
EKFNCIHE_00717 5.2e-27 Q PFAM Collagen triple helix
EKFNCIHE_00718 6.1e-22 M1-820 Q Collagen triple helix repeat (20 copies)
EKFNCIHE_00719 8.9e-24 M1-820 Q Collagen triple helix repeat (20 copies)
EKFNCIHE_00720 0.0 ywpD T PhoQ Sensor
EKFNCIHE_00721 1.6e-151 M1-574 T Transcriptional regulatory protein, C terminal
EKFNCIHE_00722 0.0 M1-568 M cell wall anchor domain
EKFNCIHE_00723 4.6e-80 srtA 3.4.22.70 M Sortase family
EKFNCIHE_00724 3.7e-272 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EKFNCIHE_00725 2.6e-118 citT T response regulator
EKFNCIHE_00726 4.6e-177 yflP S Tripartite tricarboxylate transporter family receptor
EKFNCIHE_00727 1e-224 citM C Citrate transporter
EKFNCIHE_00728 4.8e-148 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
EKFNCIHE_00729 6.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EKFNCIHE_00730 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EKFNCIHE_00731 3.7e-122 yflK S protein conserved in bacteria
EKFNCIHE_00732 1.5e-14 yflJ S Protein of unknown function (DUF2639)
EKFNCIHE_00733 7e-19 yflI
EKFNCIHE_00734 3.1e-50 yflH S Protein of unknown function (DUF3243)
EKFNCIHE_00735 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
EKFNCIHE_00736 2.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EKFNCIHE_00737 1.4e-72 yfmQ S Uncharacterised protein from bacillus cereus group
EKFNCIHE_00738 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EKFNCIHE_00739 2.3e-63 yhdN S Domain of unknown function (DUF1992)
EKFNCIHE_00740 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
EKFNCIHE_00741 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
EKFNCIHE_00742 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
EKFNCIHE_00743 2.8e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EKFNCIHE_00744 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EKFNCIHE_00745 2e-129 treR K transcriptional
EKFNCIHE_00746 1.2e-123 yfkO C nitroreductase
EKFNCIHE_00747 8.7e-123 yibF S YibE/F-like protein
EKFNCIHE_00748 3.8e-199 yibE S YibE/F-like protein
EKFNCIHE_00749 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
EKFNCIHE_00750 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
EKFNCIHE_00751 1.3e-185 K helix_turn _helix lactose operon repressor
EKFNCIHE_00752 5.6e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EKFNCIHE_00753 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EKFNCIHE_00754 8.1e-192 ydiM EGP Major facilitator Superfamily
EKFNCIHE_00755 2.7e-29 yfkK S Belongs to the UPF0435 family
EKFNCIHE_00756 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EKFNCIHE_00757 1e-51 yfkI S gas vesicle protein
EKFNCIHE_00758 7.6e-144 yihY S Belongs to the UPF0761 family
EKFNCIHE_00759 2.5e-07
EKFNCIHE_00760 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
EKFNCIHE_00761 2.2e-185 cax P COG0387 Ca2 H antiporter
EKFNCIHE_00762 1.6e-143 yfkD S YfkD-like protein
EKFNCIHE_00763 6.8e-145 yfkC M Mechanosensitive ion channel
EKFNCIHE_00764 7.3e-219 yfkA S YfkB-like domain
EKFNCIHE_00765 4.9e-27 yfjT
EKFNCIHE_00766 9e-155 pdaA G deacetylase
EKFNCIHE_00767 7.5e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EKFNCIHE_00768 7.4e-30
EKFNCIHE_00769 8.5e-184 corA P Mediates influx of magnesium ions
EKFNCIHE_00770 7.5e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EKFNCIHE_00771 6.2e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EKFNCIHE_00772 5.8e-44 S YfzA-like protein
EKFNCIHE_00773 3.5e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EKFNCIHE_00774 3.7e-87 yfjM S Psort location Cytoplasmic, score
EKFNCIHE_00775 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EKFNCIHE_00776 8e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EKFNCIHE_00777 1.9e-212 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EKFNCIHE_00778 6.2e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EKFNCIHE_00779 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
EKFNCIHE_00780 2.7e-14 sspH S Belongs to the SspH family
EKFNCIHE_00781 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EKFNCIHE_00782 5.1e-139 glvR F Helix-turn-helix domain, rpiR family
EKFNCIHE_00783 1.8e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EKFNCIHE_00784 2.4e-309 yfiB3 V ABC transporter
EKFNCIHE_00785 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
EKFNCIHE_00786 9.2e-63 mhqP S DoxX
EKFNCIHE_00787 2.5e-158 yfiE 1.13.11.2 S glyoxalase
EKFNCIHE_00788 1.7e-163 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EKFNCIHE_00789 1.1e-95 padR K transcriptional
EKFNCIHE_00790 7.9e-111 1.6.5.2 S NADPH-dependent FMN reductase
EKFNCIHE_00791 3.2e-179 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EKFNCIHE_00792 2e-19 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EKFNCIHE_00793 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
EKFNCIHE_00794 4.5e-45 yrdF K ribonuclease inhibitor
EKFNCIHE_00795 2.9e-96 yfiT S Belongs to the metal hydrolase YfiT family
EKFNCIHE_00796 4.7e-288 yfiU EGP Major facilitator Superfamily
EKFNCIHE_00797 6.2e-82 yfiV K transcriptional
EKFNCIHE_00798 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EKFNCIHE_00799 7.2e-161 yfhB 5.3.3.17 S PhzF family
EKFNCIHE_00800 1.7e-105 yfhC C nitroreductase
EKFNCIHE_00801 2.1e-25 yfhD S YfhD-like protein
EKFNCIHE_00803 2.2e-165 yfhF S nucleoside-diphosphate sugar epimerase
EKFNCIHE_00804 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
EKFNCIHE_00805 2.5e-52 yfhH S Protein of unknown function (DUF1811)
EKFNCIHE_00806 1.1e-204 yfhI EGP Major facilitator Superfamily
EKFNCIHE_00808 2e-166 mpr 3.4.21.19 M Belongs to the peptidase S1B family
EKFNCIHE_00809 2.2e-44 yfhJ S WVELL protein
EKFNCIHE_00810 1.5e-92 batE T Bacterial SH3 domain homologues
EKFNCIHE_00811 2e-31 yfhL S SdpI/YhfL protein family
EKFNCIHE_00812 1.7e-170 yfhM S Alpha/beta hydrolase family
EKFNCIHE_00813 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EKFNCIHE_00814 0.0 yfhO S Bacterial membrane protein YfhO
EKFNCIHE_00815 1e-184 yfhP S membrane-bound metal-dependent
EKFNCIHE_00816 4.8e-207 mutY L A G-specific
EKFNCIHE_00817 3.1e-36 yfhS
EKFNCIHE_00818 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFNCIHE_00820 1.5e-37 ygaB S YgaB-like protein
EKFNCIHE_00821 2.2e-104 ygaC J Belongs to the UPF0374 family
EKFNCIHE_00822 5e-299 ygaD V ABC transporter
EKFNCIHE_00823 2.7e-178 ygaE S Membrane
EKFNCIHE_00824 3.1e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
EKFNCIHE_00825 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
EKFNCIHE_00826 1.8e-80 perR P Belongs to the Fur family
EKFNCIHE_00827 1.5e-56 ygzB S UPF0295 protein
EKFNCIHE_00828 1.1e-164 ygxA S Nucleotidyltransferase-like
EKFNCIHE_00829 3.4e-39 S COG NOG14552 non supervised orthologous group
EKFNCIHE_00834 7.8e-08
EKFNCIHE_00842 1.6e-08
EKFNCIHE_00846 1.4e-18 C Na+/H+ antiporter family
EKFNCIHE_00847 2e-129 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
EKFNCIHE_00848 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EKFNCIHE_00849 9e-264 ygaK C Berberine and berberine like
EKFNCIHE_00851 8.3e-230 oppA5 E PFAM extracellular solute-binding protein family 5
EKFNCIHE_00852 3.7e-147 appB P Binding-protein-dependent transport system inner membrane component
EKFNCIHE_00853 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKFNCIHE_00854 5.8e-135 oppD3 P Belongs to the ABC transporter superfamily
EKFNCIHE_00855 5.3e-133 oppF3 E Belongs to the ABC transporter superfamily
EKFNCIHE_00856 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
EKFNCIHE_00857 1.7e-181 S Amidohydrolase
EKFNCIHE_00858 6.1e-140 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EKFNCIHE_00859 3.7e-166 ssuA M Sulfonate ABC transporter
EKFNCIHE_00860 1.3e-143 ssuC P ABC transporter (permease)
EKFNCIHE_00861 3.8e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
EKFNCIHE_00862 1.2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EKFNCIHE_00863 8.6e-81 ygaO
EKFNCIHE_00864 4.8e-23 K Transcriptional regulator
EKFNCIHE_00866 5.5e-107 yhzB S B3/4 domain
EKFNCIHE_00867 1.7e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EKFNCIHE_00868 5.1e-173 yhbB S Putative amidase domain
EKFNCIHE_00869 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EKFNCIHE_00870 1.1e-107 yhbD K Protein of unknown function (DUF4004)
EKFNCIHE_00871 8.9e-61 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
EKFNCIHE_00872 5.5e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
EKFNCIHE_00874 0.0 prkA T Ser protein kinase
EKFNCIHE_00875 3.9e-215 yhbH S Belongs to the UPF0229 family
EKFNCIHE_00876 4.6e-74 yhbI K DNA-binding transcription factor activity
EKFNCIHE_00877 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
EKFNCIHE_00878 8.4e-285 yhcA EGP Major facilitator Superfamily
EKFNCIHE_00879 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
EKFNCIHE_00880 3.8e-55 yhcC
EKFNCIHE_00881 1.6e-52
EKFNCIHE_00882 2.8e-61 yhcF K Transcriptional regulator
EKFNCIHE_00883 1.3e-123 yhcG V ABC transporter, ATP-binding protein
EKFNCIHE_00884 7.7e-166 yhcH V ABC transporter, ATP-binding protein
EKFNCIHE_00885 8.2e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EKFNCIHE_00886 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
EKFNCIHE_00887 8.3e-143 metQ M Belongs to the nlpA lipoprotein family
EKFNCIHE_00888 2.5e-184 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
EKFNCIHE_00889 1.1e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKFNCIHE_00890 1e-51 yhcM
EKFNCIHE_00891 4.8e-83 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EKFNCIHE_00892 1.4e-159 yhcP
EKFNCIHE_00893 8.4e-114 yhcQ M Spore coat protein
EKFNCIHE_00894 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
EKFNCIHE_00895 1.7e-105 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
EKFNCIHE_00896 4e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EKFNCIHE_00897 1.3e-69 yhcU S Family of unknown function (DUF5365)
EKFNCIHE_00898 9.9e-68 yhcV S COG0517 FOG CBS domain
EKFNCIHE_00899 4.9e-125 yhcW 5.4.2.6 S hydrolase
EKFNCIHE_00900 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EKFNCIHE_00901 2.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EKFNCIHE_00902 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EKFNCIHE_00903 7.7e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
EKFNCIHE_00904 1.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EKFNCIHE_00905 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EKFNCIHE_00906 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
EKFNCIHE_00907 7e-201 yhcY 2.7.13.3 T Histidine kinase
EKFNCIHE_00908 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFNCIHE_00909 7.4e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
EKFNCIHE_00910 2.5e-39 yhdB S YhdB-like protein
EKFNCIHE_00911 1.1e-53 yhdC S Protein of unknown function (DUF3889)
EKFNCIHE_00912 3.4e-216 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EKFNCIHE_00913 1.6e-73 nsrR K Transcriptional regulator
EKFNCIHE_00914 3.1e-244 ygxB M Conserved TM helix
EKFNCIHE_00915 1.8e-270 ycgB S Stage V sporulation protein R
EKFNCIHE_00916 1.3e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
EKFNCIHE_00917 3.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EKFNCIHE_00918 1.3e-162 citR K Transcriptional regulator
EKFNCIHE_00919 5.9e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
EKFNCIHE_00920 5.1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFNCIHE_00921 1.2e-250 yhdG E amino acid
EKFNCIHE_00922 3e-195 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EKFNCIHE_00923 8.1e-45 yhdK S Sigma-M inhibitor protein
EKFNCIHE_00924 1.3e-201 yhdL S Sigma factor regulator N-terminal
EKFNCIHE_00925 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
EKFNCIHE_00926 4.8e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EKFNCIHE_00927 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
EKFNCIHE_00928 2.8e-70 cueR K transcriptional
EKFNCIHE_00929 1.9e-225 yhdR 2.6.1.1 E Aminotransferase
EKFNCIHE_00930 4.7e-235 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EKFNCIHE_00931 6e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
EKFNCIHE_00932 1.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EKFNCIHE_00933 3.3e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EKFNCIHE_00934 1.8e-125 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EKFNCIHE_00936 3.5e-205 yhdY M Mechanosensitive ion channel
EKFNCIHE_00937 2.9e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EKFNCIHE_00938 1.1e-155 yheN G deacetylase
EKFNCIHE_00939 9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EKFNCIHE_00940 3e-87 pksA K Transcriptional regulator
EKFNCIHE_00941 1.8e-93 ymcC S Membrane
EKFNCIHE_00942 6.2e-85 T universal stress protein
EKFNCIHE_00944 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
EKFNCIHE_00945 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
EKFNCIHE_00946 1.6e-111 yheG GM NAD(P)H-binding
EKFNCIHE_00948 1.3e-28 sspB S spore protein
EKFNCIHE_00949 1.7e-36 yheE S Family of unknown function (DUF5342)
EKFNCIHE_00950 1.5e-258 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
EKFNCIHE_00951 3.4e-213 yheC HJ YheC/D like ATP-grasp
EKFNCIHE_00952 3.6e-205 yheB S Belongs to the UPF0754 family
EKFNCIHE_00953 4.4e-53 yheA S Belongs to the UPF0342 family
EKFNCIHE_00954 1.4e-201 yhaZ L DNA alkylation repair enzyme
EKFNCIHE_00955 4.7e-157 yhaX S haloacid dehalogenase-like hydrolase
EKFNCIHE_00956 2.7e-293 hemZ H coproporphyrinogen III oxidase
EKFNCIHE_00957 2.7e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
EKFNCIHE_00958 2.6e-206 yhaU P COG0475 Kef-type K transport systems, membrane components
EKFNCIHE_00959 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
EKFNCIHE_00961 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
EKFNCIHE_00962 2.8e-14 S YhzD-like protein
EKFNCIHE_00963 4.4e-166 yhaQ S ABC transporter, ATP-binding protein
EKFNCIHE_00964 1.2e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
EKFNCIHE_00965 4.7e-235 yhaO L DNA repair exonuclease
EKFNCIHE_00966 0.0 yhaN L AAA domain
EKFNCIHE_00967 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
EKFNCIHE_00968 1.8e-31 yhaL S Sporulation protein YhaL
EKFNCIHE_00969 9.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EKFNCIHE_00970 7e-95 yhaK S Putative zincin peptidase
EKFNCIHE_00971 9.9e-55 yhaI S Protein of unknown function (DUF1878)
EKFNCIHE_00972 8.6e-113 hpr K Negative regulator of protease production and sporulation
EKFNCIHE_00973 6.2e-39 yhaH S YtxH-like protein
EKFNCIHE_00974 2e-17
EKFNCIHE_00975 1.4e-76 trpP S Tryptophan transporter TrpP
EKFNCIHE_00976 6e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EKFNCIHE_00977 4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EKFNCIHE_00978 1.1e-135 ecsA V transporter (ATP-binding protein)
EKFNCIHE_00979 8.5e-221 ecsB U ABC transporter
EKFNCIHE_00980 4e-122 ecsC S EcsC protein family
EKFNCIHE_00981 2.2e-221 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EKFNCIHE_00982 6.2e-244 yhfA C membrane
EKFNCIHE_00983 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
EKFNCIHE_00984 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EKFNCIHE_00985 9.5e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EKFNCIHE_00986 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EKFNCIHE_00987 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EKFNCIHE_00989 3.2e-101 yhgD K Transcriptional regulator
EKFNCIHE_00990 4.7e-244 yhgE S YhgE Pip N-terminal domain protein
EKFNCIHE_00991 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKFNCIHE_00993 6.6e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
EKFNCIHE_00994 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKFNCIHE_00995 7.9e-11 yhfH S YhfH-like protein
EKFNCIHE_00996 2.2e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EKFNCIHE_00997 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
EKFNCIHE_00998 1.4e-108 yhfK GM NmrA-like family
EKFNCIHE_00999 1.2e-296 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
EKFNCIHE_01000 1.9e-65 yhfM
EKFNCIHE_01001 3.6e-235 yhfN 3.4.24.84 O Peptidase M48
EKFNCIHE_01002 2.2e-202 aprE 3.4.21.62 O Belongs to the peptidase S8 family
EKFNCIHE_01003 1.6e-149 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EKFNCIHE_01004 4.4e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
EKFNCIHE_01005 6.7e-201 vraB 2.3.1.9 I Belongs to the thiolase family
EKFNCIHE_01006 4.7e-279 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
EKFNCIHE_01007 4.6e-89 bioY S BioY family
EKFNCIHE_01008 1.2e-196 hemAT NT chemotaxis protein
EKFNCIHE_01009 1.6e-296 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
EKFNCIHE_01010 6.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFNCIHE_01011 5.4e-31 yhzC S IDEAL
EKFNCIHE_01012 1.9e-109 comK K Competence transcription factor
EKFNCIHE_01013 4.7e-66 frataxin S Domain of unknown function (DU1801)
EKFNCIHE_01014 6e-61 frataxin S Domain of unknown function (DU1801)
EKFNCIHE_01015 8.7e-125 yrpD S Domain of unknown function, YrpD
EKFNCIHE_01016 1.6e-42 yhjA S Excalibur calcium-binding domain
EKFNCIHE_01017 3.3e-47 S Belongs to the UPF0145 family
EKFNCIHE_01018 3.8e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKFNCIHE_01019 3.1e-27 yhjC S Protein of unknown function (DUF3311)
EKFNCIHE_01020 5e-60 yhjD
EKFNCIHE_01021 7.7e-109 yhjE S SNARE associated Golgi protein
EKFNCIHE_01022 1.6e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
EKFNCIHE_01024 9.2e-270 yhjG CH FAD binding domain
EKFNCIHE_01025 8.4e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
EKFNCIHE_01026 1.2e-187 abrB S membrane
EKFNCIHE_01027 3e-202 blt EGP Major facilitator Superfamily
EKFNCIHE_01028 1.1e-107 K QacR-like protein, C-terminal region
EKFNCIHE_01029 6.3e-93 yhjR S Rubrerythrin
EKFNCIHE_01030 2.5e-119 ydfS S Protein of unknown function (DUF421)
EKFNCIHE_01031 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
EKFNCIHE_01032 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EKFNCIHE_01033 1.1e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EKFNCIHE_01034 0.0 sbcC L COG0419 ATPase involved in DNA repair
EKFNCIHE_01035 1.3e-50 yisB V COG1403 Restriction endonuclease
EKFNCIHE_01036 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
EKFNCIHE_01037 1.1e-63 gerPE S Spore germination protein GerPE
EKFNCIHE_01038 9.1e-23 gerPD S Spore germination protein
EKFNCIHE_01039 1.4e-62 gerPC S Spore germination protein
EKFNCIHE_01040 1.8e-34 gerPB S cell differentiation
EKFNCIHE_01041 8.4e-34 gerPA S Spore germination protein
EKFNCIHE_01042 4.8e-07 yisI S Spo0E like sporulation regulatory protein
EKFNCIHE_01043 1.3e-170 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EKFNCIHE_01044 3.2e-59 yisL S UPF0344 protein
EKFNCIHE_01045 3.4e-97 yisN S Protein of unknown function (DUF2777)
EKFNCIHE_01046 0.0 asnO 6.3.5.4 E Asparagine synthase
EKFNCIHE_01047 3.6e-129 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
EKFNCIHE_01048 1.5e-245 yisQ V Mate efflux family protein
EKFNCIHE_01049 2.3e-159 yisR K Transcriptional regulator
EKFNCIHE_01050 9.2e-144 purR K helix_turn _helix lactose operon repressor
EKFNCIHE_01051 5.8e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
EKFNCIHE_01052 1.2e-83 yisT S DinB family
EKFNCIHE_01053 1.6e-69 mcbG S Pentapeptide repeats (9 copies)
EKFNCIHE_01054 2.4e-80 yjcF S Acetyltransferase (GNAT) domain
EKFNCIHE_01055 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EKFNCIHE_01056 6.6e-55 yajQ S Belongs to the UPF0234 family
EKFNCIHE_01057 7.6e-160 cvfB S protein conserved in bacteria
EKFNCIHE_01058 1.9e-170 yufN S ABC transporter substrate-binding protein PnrA-like
EKFNCIHE_01059 9.1e-218 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
EKFNCIHE_01061 3e-156 yitS S protein conserved in bacteria
EKFNCIHE_01062 1.5e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
EKFNCIHE_01063 1.2e-79 ipi S Intracellular proteinase inhibitor
EKFNCIHE_01064 4.4e-26 S Protein of unknown function (DUF3813)
EKFNCIHE_01065 3.5e-07
EKFNCIHE_01066 5.1e-153 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EKFNCIHE_01067 3.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
EKFNCIHE_01068 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
EKFNCIHE_01069 5.1e-72 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EKFNCIHE_01070 3.3e-272 yitY C D-arabinono-1,4-lactone oxidase
EKFNCIHE_01071 1.2e-89 norB G Major Facilitator Superfamily
EKFNCIHE_01072 3.3e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EKFNCIHE_01073 1.7e-224 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EKFNCIHE_01074 7e-136 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
EKFNCIHE_01075 4.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
EKFNCIHE_01076 2e-202 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EKFNCIHE_01077 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
EKFNCIHE_01078 7.8e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EKFNCIHE_01079 1.2e-27 yjzC S YjzC-like protein
EKFNCIHE_01080 3.3e-23 yjzD S Protein of unknown function (DUF2929)
EKFNCIHE_01081 4.6e-137 yjaU I carboxylic ester hydrolase activity
EKFNCIHE_01082 8.8e-104 yjaV
EKFNCIHE_01083 2.7e-165 med S Transcriptional activator protein med
EKFNCIHE_01084 1.1e-26 comZ S ComZ
EKFNCIHE_01085 1e-31 yjzB
EKFNCIHE_01086 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKFNCIHE_01087 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EKFNCIHE_01088 5.6e-149 yjaZ O Zn-dependent protease
EKFNCIHE_01089 4.8e-182 appD P Belongs to the ABC transporter superfamily
EKFNCIHE_01090 5.1e-88 appF E Belongs to the ABC transporter superfamily
EKFNCIHE_01091 4.1e-83 appF E Belongs to the ABC transporter superfamily
EKFNCIHE_01092 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
EKFNCIHE_01093 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKFNCIHE_01094 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKFNCIHE_01095 6.1e-145 yjbA S Belongs to the UPF0736 family
EKFNCIHE_01096 2.6e-183 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EKFNCIHE_01097 0.0 oppA E ABC transporter substrate-binding protein
EKFNCIHE_01098 3.5e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKFNCIHE_01099 1.7e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKFNCIHE_01100 2.7e-202 oppD P Belongs to the ABC transporter superfamily
EKFNCIHE_01101 2.3e-170 oppF E Belongs to the ABC transporter superfamily
EKFNCIHE_01102 9.8e-230 S Putative glycosyl hydrolase domain
EKFNCIHE_01103 4.9e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKFNCIHE_01104 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EKFNCIHE_01105 4.7e-109 yjbE P Integral membrane protein TerC family
EKFNCIHE_01106 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EKFNCIHE_01107 9.3e-217 yjbF S Competence protein
EKFNCIHE_01108 0.0 pepF E oligoendopeptidase F
EKFNCIHE_01109 5.8e-19
EKFNCIHE_01110 6.6e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
EKFNCIHE_01111 4.8e-72 yjbI S Bacterial-like globin
EKFNCIHE_01112 3.5e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EKFNCIHE_01113 4e-96 yjbK S protein conserved in bacteria
EKFNCIHE_01114 6e-61 yjbL S Belongs to the UPF0738 family
EKFNCIHE_01115 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
EKFNCIHE_01116 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EKFNCIHE_01117 3.7e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EKFNCIHE_01118 2.6e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EKFNCIHE_01119 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EKFNCIHE_01120 9.9e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EKFNCIHE_01121 2.1e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
EKFNCIHE_01122 1.4e-209 thiO 1.4.3.19 E Glycine oxidase
EKFNCIHE_01123 6.7e-30 thiS H Thiamine biosynthesis
EKFNCIHE_01124 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EKFNCIHE_01125 4.3e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EKFNCIHE_01126 6.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EKFNCIHE_01127 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
EKFNCIHE_01128 1.5e-88 yjbX S Spore coat protein
EKFNCIHE_01129 6.7e-83 cotZ S Spore coat protein
EKFNCIHE_01130 1e-92 cotY S Spore coat protein Z
EKFNCIHE_01131 5.1e-71 cotX S Spore Coat Protein X and V domain
EKFNCIHE_01132 6.8e-21 cotW
EKFNCIHE_01133 1.4e-52 cotV S Spore Coat Protein X and V domain
EKFNCIHE_01134 1.6e-55 yjcA S Protein of unknown function (DUF1360)
EKFNCIHE_01138 3.8e-38 spoVIF S Stage VI sporulation protein F
EKFNCIHE_01139 0.0 yjcD 3.6.4.12 L DNA helicase
EKFNCIHE_01140 1.3e-35
EKFNCIHE_01141 2.2e-139 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
EKFNCIHE_01142 5.7e-124 S ABC-2 type transporter
EKFNCIHE_01143 1.3e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
EKFNCIHE_01144 2.7e-35 K SpoVT / AbrB like domain
EKFNCIHE_01146 2.3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKFNCIHE_01147 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
EKFNCIHE_01148 3.6e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
EKFNCIHE_01149 8.7e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EKFNCIHE_01150 2.2e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EKFNCIHE_01152 6e-191 L Belongs to the 'phage' integrase family
EKFNCIHE_01153 1.1e-103 S Helix-turn-helix domain
EKFNCIHE_01154 6.6e-100 L Belongs to the 'phage' integrase family
EKFNCIHE_01157 8.7e-13 S Cro/C1-type HTH DNA-binding domain
EKFNCIHE_01158 4.2e-24
EKFNCIHE_01162 2.3e-14
EKFNCIHE_01164 4.1e-119
EKFNCIHE_01166 8.1e-29
EKFNCIHE_01167 5.4e-12 K Helix-turn-helix XRE-family like proteins
EKFNCIHE_01168 4.7e-18
EKFNCIHE_01173 8.4e-11
EKFNCIHE_01175 2.1e-153 D phage tail tape measure protein
EKFNCIHE_01176 9.1e-11 NU Prophage endopeptidase tail
EKFNCIHE_01177 2.4e-30 S KTSC domain
EKFNCIHE_01179 2.6e-21
EKFNCIHE_01180 1.5e-306 yobL S Bacterial EndoU nuclease
EKFNCIHE_01183 2.9e-58 E Glyoxalase-like domain
EKFNCIHE_01185 6.3e-160 bla 3.5.2.6 V beta-lactamase
EKFNCIHE_01186 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
EKFNCIHE_01187 4.5e-250 yfjF EGP Belongs to the major facilitator superfamily
EKFNCIHE_01188 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
EKFNCIHE_01189 3.8e-220 ganA 3.2.1.89 G arabinogalactan
EKFNCIHE_01190 3.2e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EKFNCIHE_01191 1e-184 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EKFNCIHE_01192 1.1e-212 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EKFNCIHE_01193 6.4e-307 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKFNCIHE_01194 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
EKFNCIHE_01195 6.9e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
EKFNCIHE_01196 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
EKFNCIHE_01197 1e-122 5.4.2.6 S Haloacid dehalogenase-like hydrolase
EKFNCIHE_01199 8.1e-106 yhiD S MgtC SapB transporter
EKFNCIHE_01200 3.7e-21 yjfB S Putative motility protein
EKFNCIHE_01201 2.3e-66 T PhoQ Sensor
EKFNCIHE_01202 1.3e-99 yjgB S Domain of unknown function (DUF4309)
EKFNCIHE_01203 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
EKFNCIHE_01204 4.3e-92 yjgD S Protein of unknown function (DUF1641)
EKFNCIHE_01205 4.4e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
EKFNCIHE_01206 7.7e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EKFNCIHE_01207 6.8e-29
EKFNCIHE_01208 5.8e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
EKFNCIHE_01209 2.1e-124 ybbM S transport system, permease component
EKFNCIHE_01210 1.3e-128 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
EKFNCIHE_01211 1.7e-174 yjlA EG Putative multidrug resistance efflux transporter
EKFNCIHE_01212 5.7e-91 yjlB S Cupin domain
EKFNCIHE_01213 7e-66 yjlC S Protein of unknown function (DUF1641)
EKFNCIHE_01214 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
EKFNCIHE_01215 4.8e-276 uxaC 5.3.1.12 G glucuronate isomerase
EKFNCIHE_01216 2.5e-253 yjmB G symporter YjmB
EKFNCIHE_01217 7e-181 exuR K transcriptional
EKFNCIHE_01218 2.9e-276 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
EKFNCIHE_01219 1.3e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
EKFNCIHE_01220 4e-87 T Transcriptional regulatory protein, C terminal
EKFNCIHE_01221 1.4e-131 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EKFNCIHE_01222 8.5e-104 V ABC transporter, ATP-binding protein
EKFNCIHE_01223 2.7e-65 S ABC-2 family transporter protein
EKFNCIHE_01225 1.7e-46 narQ 2.7.13.3 T Histidine kinase
EKFNCIHE_01226 5.4e-60 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFNCIHE_01228 8.2e-300 lcnDR2 V Lanthionine synthetase C-like protein
EKFNCIHE_01229 1.1e-220 lanT 3.6.3.27 V Peptidase C39 family
EKFNCIHE_01232 3.4e-204 salB V Domain of unknown function (DUF4135)
EKFNCIHE_01233 1.5e-130 MA20_18170 S membrane transporter protein
EKFNCIHE_01234 1.5e-77 yjoA S DinB family
EKFNCIHE_01235 4.9e-215 S response regulator aspartate phosphatase
EKFNCIHE_01237 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EKFNCIHE_01238 8e-61 yjqA S Bacterial PH domain
EKFNCIHE_01239 6.7e-110 yjqB S phage-related replication protein
EKFNCIHE_01241 2.9e-110 xkdA E IrrE N-terminal-like domain
EKFNCIHE_01242 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
EKFNCIHE_01244 5.2e-150 xkdC L Bacterial dnaA protein
EKFNCIHE_01247 2e-10 yqaO S Phage-like element PBSX protein XtrA
EKFNCIHE_01248 4.9e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EKFNCIHE_01249 3e-110 xtmA L phage terminase small subunit
EKFNCIHE_01250 8.5e-211 xtmB S phage terminase, large subunit
EKFNCIHE_01251 5.1e-241 yqbA S portal protein
EKFNCIHE_01252 9.8e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
EKFNCIHE_01253 4.6e-158 xkdG S Phage capsid family
EKFNCIHE_01254 4.3e-46 yqbG S Protein of unknown function (DUF3199)
EKFNCIHE_01255 5.5e-43 yqbH S Domain of unknown function (DUF3599)
EKFNCIHE_01256 5.3e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
EKFNCIHE_01257 3.2e-56 xkdJ
EKFNCIHE_01258 8.2e-15
EKFNCIHE_01259 3.5e-226 xkdK S Phage tail sheath C-terminal domain
EKFNCIHE_01260 2e-74 xkdM S Phage tail tube protein
EKFNCIHE_01261 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
EKFNCIHE_01262 3.4e-19
EKFNCIHE_01263 3e-203 xkdO L Transglycosylase SLT domain
EKFNCIHE_01264 3.9e-111 xkdP S Lysin motif
EKFNCIHE_01265 9.4e-162 xkdQ 3.2.1.96 G NLP P60 protein
EKFNCIHE_01266 7.2e-32 xkdR S Protein of unknown function (DUF2577)
EKFNCIHE_01267 4.2e-58 xkdS S Protein of unknown function (DUF2634)
EKFNCIHE_01268 6.7e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EKFNCIHE_01269 8.5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
EKFNCIHE_01270 1.2e-26
EKFNCIHE_01271 1.7e-91
EKFNCIHE_01273 1.6e-28 xkdX
EKFNCIHE_01274 2.6e-135 xepA
EKFNCIHE_01275 8.7e-38 xhlA S Haemolysin XhlA
EKFNCIHE_01276 1.3e-38 xhlB S SPP1 phage holin
EKFNCIHE_01277 1.6e-168 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EKFNCIHE_01278 8.7e-23 spoIISB S Stage II sporulation protein SB
EKFNCIHE_01279 5.9e-132 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
EKFNCIHE_01280 5.8e-175 pit P phosphate transporter
EKFNCIHE_01281 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
EKFNCIHE_01282 1.1e-242 steT E amino acid
EKFNCIHE_01283 3.1e-178 mhqA E COG0346 Lactoylglutathione lyase and related lyases
EKFNCIHE_01284 5.7e-305 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EKFNCIHE_01285 4.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EKFNCIHE_01286 1.5e-16 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EKFNCIHE_01287 1.2e-204 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKFNCIHE_01288 9.7e-278 yubD P Major Facilitator Superfamily
EKFNCIHE_01289 9.3e-155 dppA E D-aminopeptidase
EKFNCIHE_01290 1.2e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKFNCIHE_01291 1.1e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKFNCIHE_01292 2.9e-190 dppD P Belongs to the ABC transporter superfamily
EKFNCIHE_01293 0.0 dppE E ABC transporter substrate-binding protein
EKFNCIHE_01294 2.6e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
EKFNCIHE_01295 2.4e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
EKFNCIHE_01296 3e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EKFNCIHE_01297 1.6e-182 ykfD E Belongs to the ABC transporter superfamily
EKFNCIHE_01298 1.1e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
EKFNCIHE_01299 1.5e-158 ykgA E Amidinotransferase
EKFNCIHE_01300 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
EKFNCIHE_01301 1.1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EKFNCIHE_01302 1.4e-51 ykkC P Multidrug resistance protein
EKFNCIHE_01303 2.9e-48 ykkD P Multidrug resistance protein
EKFNCIHE_01304 3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EKFNCIHE_01305 1.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EKFNCIHE_01306 1.3e-224 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EKFNCIHE_01307 2.6e-68 ohrA O Organic hydroperoxide resistance protein
EKFNCIHE_01308 1.1e-72 ohrR K COG1846 Transcriptional regulators
EKFNCIHE_01309 4.2e-71 ohrB O Organic hydroperoxide resistance protein
EKFNCIHE_01310 8.8e-52 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EKFNCIHE_01312 3.8e-215 M Glycosyl transferase family 2
EKFNCIHE_01313 1.4e-123 M PFAM Collagen triple helix repeat (20 copies)
EKFNCIHE_01314 1.2e-214 hcaT 1.5.1.2 EGP Major facilitator Superfamily
EKFNCIHE_01315 2e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EKFNCIHE_01316 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EKFNCIHE_01317 5e-176 isp O Belongs to the peptidase S8 family
EKFNCIHE_01318 4.3e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EKFNCIHE_01319 1.2e-132 ykoC P Cobalt transport protein
EKFNCIHE_01320 1.3e-301 P ABC transporter, ATP-binding protein
EKFNCIHE_01321 1.3e-97 ykoE S ABC-type cobalt transport system, permease component
EKFNCIHE_01322 7.4e-244 ydhD M Glycosyl hydrolase
EKFNCIHE_01324 3.2e-237 mgtE P Acts as a magnesium transporter
EKFNCIHE_01325 5.4e-53 tnrA K transcriptional
EKFNCIHE_01326 1.9e-16
EKFNCIHE_01327 3.1e-26 ykoL
EKFNCIHE_01328 1.1e-80 ykoM K transcriptional
EKFNCIHE_01329 3.7e-99 ykoP G polysaccharide deacetylase
EKFNCIHE_01330 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
EKFNCIHE_01331 4.6e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EKFNCIHE_01332 6.6e-99 ykoX S membrane-associated protein
EKFNCIHE_01333 1.5e-133 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EKFNCIHE_01334 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFNCIHE_01335 1.5e-118 rsgI S Anti-sigma factor N-terminus
EKFNCIHE_01336 2.5e-26 sspD S small acid-soluble spore protein
EKFNCIHE_01337 8.6e-125 ykrK S Domain of unknown function (DUF1836)
EKFNCIHE_01338 4.5e-155 htpX O Belongs to the peptidase M48B family
EKFNCIHE_01339 4.8e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
EKFNCIHE_01340 7.2e-113 ydfR S Protein of unknown function (DUF421)
EKFNCIHE_01341 8.7e-23 ykzE
EKFNCIHE_01342 2.1e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
EKFNCIHE_01343 0.0 kinE 2.7.13.3 T Histidine kinase
EKFNCIHE_01344 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKFNCIHE_01346 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EKFNCIHE_01347 7.2e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EKFNCIHE_01348 8.6e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EKFNCIHE_01349 3.5e-227 mtnE 2.6.1.83 E Aminotransferase
EKFNCIHE_01350 2.5e-225 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EKFNCIHE_01351 1.4e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EKFNCIHE_01352 8e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EKFNCIHE_01353 4.6e-94 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EKFNCIHE_01354 3.4e-10 S Spo0E like sporulation regulatory protein
EKFNCIHE_01355 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
EKFNCIHE_01356 5.5e-77 ykvE K transcriptional
EKFNCIHE_01357 2.7e-127 motB N Flagellar motor protein
EKFNCIHE_01358 3.3e-136 motA N flagellar motor
EKFNCIHE_01359 0.0 clpE O Belongs to the ClpA ClpB family
EKFNCIHE_01360 1.3e-182 ykvI S membrane
EKFNCIHE_01361 1.8e-185
EKFNCIHE_01362 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EKFNCIHE_01363 1.7e-78 queD 4.1.2.50, 4.2.3.12 H synthase
EKFNCIHE_01364 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EKFNCIHE_01365 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EKFNCIHE_01366 1e-44 ykvR S Protein of unknown function (DUF3219)
EKFNCIHE_01367 7.8e-25 ykvS S protein conserved in bacteria
EKFNCIHE_01368 3.9e-27
EKFNCIHE_01369 5.3e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
EKFNCIHE_01370 1.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKFNCIHE_01371 1.7e-87 stoA CO thiol-disulfide
EKFNCIHE_01372 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
EKFNCIHE_01373 6.9e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
EKFNCIHE_01375 3.3e-175 ykvZ 5.1.1.1 K Transcriptional regulator
EKFNCIHE_01376 5.1e-156 glcT K antiterminator
EKFNCIHE_01377 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EKFNCIHE_01378 2.1e-39 ptsH G phosphocarrier protein HPr
EKFNCIHE_01379 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EKFNCIHE_01380 6.1e-38 splA S Transcriptional regulator
EKFNCIHE_01381 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
EKFNCIHE_01382 2.9e-263 mcpC NT chemotaxis protein
EKFNCIHE_01383 1.6e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EKFNCIHE_01384 9.8e-114 ykwD J protein with SCP PR1 domains
EKFNCIHE_01385 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
EKFNCIHE_01386 6.8e-291 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
EKFNCIHE_01387 3.9e-215 patA 2.6.1.1 E Aminotransferase
EKFNCIHE_01388 2.3e-09
EKFNCIHE_01389 1.8e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
EKFNCIHE_01390 1.4e-83 ykyB S YkyB-like protein
EKFNCIHE_01391 1.1e-239 ykuC EGP Major facilitator Superfamily
EKFNCIHE_01392 4.1e-89 ykuD S protein conserved in bacteria
EKFNCIHE_01393 1.4e-153 ykuE S Metallophosphoesterase
EKFNCIHE_01394 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFNCIHE_01396 3.3e-233 ykuI T Diguanylate phosphodiesterase
EKFNCIHE_01397 3.9e-37 ykuJ S protein conserved in bacteria
EKFNCIHE_01398 1.4e-92 ykuK S Ribonuclease H-like
EKFNCIHE_01399 2.1e-25 ykzF S Antirepressor AbbA
EKFNCIHE_01400 1e-75 ykuL S CBS domain
EKFNCIHE_01401 1.3e-167 ccpC K Transcriptional regulator
EKFNCIHE_01402 1.3e-89 fld C Flavodoxin
EKFNCIHE_01403 5.7e-166 ykuO
EKFNCIHE_01404 2.3e-78 fld C Flavodoxin
EKFNCIHE_01405 4.5e-73 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EKFNCIHE_01406 2.9e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EKFNCIHE_01407 4.8e-38 ykuS S Belongs to the UPF0180 family
EKFNCIHE_01408 3.7e-140 ykuT M Mechanosensitive ion channel
EKFNCIHE_01409 7.4e-77 ykuV CO thiol-disulfide
EKFNCIHE_01410 4.5e-98 rok K Repressor of ComK
EKFNCIHE_01411 1.8e-160 yknT
EKFNCIHE_01412 3.7e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EKFNCIHE_01413 7.2e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EKFNCIHE_01414 1.4e-242 moeA 2.10.1.1 H molybdopterin
EKFNCIHE_01415 1.9e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
EKFNCIHE_01416 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
EKFNCIHE_01417 1.7e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EKFNCIHE_01418 4.4e-105 yknW S Yip1 domain
EKFNCIHE_01419 3.9e-167 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EKFNCIHE_01420 2e-121 macB V ABC transporter, ATP-binding protein
EKFNCIHE_01421 3e-210 yknZ V ABC transporter (permease)
EKFNCIHE_01422 1.7e-131 fruR K Transcriptional regulator
EKFNCIHE_01423 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
EKFNCIHE_01424 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EKFNCIHE_01425 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EKFNCIHE_01426 1.7e-36 ykoA
EKFNCIHE_01427 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EKFNCIHE_01428 1.7e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EKFNCIHE_01429 1e-234 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EKFNCIHE_01430 5.5e-12 S Uncharacterized protein YkpC
EKFNCIHE_01431 6.9e-184 mreB D Rod-share determining protein MreBH
EKFNCIHE_01432 1.8e-44 abrB K of stationary sporulation gene expression
EKFNCIHE_01433 3.4e-244 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
EKFNCIHE_01434 3.8e-148 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
EKFNCIHE_01435 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
EKFNCIHE_01436 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EKFNCIHE_01437 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EKFNCIHE_01438 8.2e-31 ykzG S Belongs to the UPF0356 family
EKFNCIHE_01439 7.4e-146 ykrA S hydrolases of the HAD superfamily
EKFNCIHE_01440 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EKFNCIHE_01442 2.5e-102 recN L Putative cell-wall binding lipoprotein
EKFNCIHE_01443 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EKFNCIHE_01444 0.0 Q Polyketide synthase of type I
EKFNCIHE_01445 0.0 Q polyketide synthase
EKFNCIHE_01446 0.0 Q Polyketide synthase of type I
EKFNCIHE_01447 0.0 Q Polyketide synthase of type I
EKFNCIHE_01448 0.0 Q Polyketide synthase of type I
EKFNCIHE_01449 0.0 Q Polyketide synthase of type I
EKFNCIHE_01450 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
EKFNCIHE_01451 3.3e-208 V Beta-lactamase
EKFNCIHE_01452 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EKFNCIHE_01453 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EKFNCIHE_01454 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EKFNCIHE_01455 1.2e-250 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EKFNCIHE_01456 1.8e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
EKFNCIHE_01457 3.9e-134 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
EKFNCIHE_01458 2.8e-274 speA 4.1.1.19 E Arginine
EKFNCIHE_01459 3.5e-42 yktA S Belongs to the UPF0223 family
EKFNCIHE_01460 1.8e-118 yktB S Belongs to the UPF0637 family
EKFNCIHE_01461 6.3e-24 ykzI
EKFNCIHE_01462 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
EKFNCIHE_01463 4e-83 ykzC S Acetyltransferase (GNAT) family
EKFNCIHE_01464 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
EKFNCIHE_01465 2.2e-186 ylaA
EKFNCIHE_01466 1.9e-43 ylaB
EKFNCIHE_01467 1.2e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
EKFNCIHE_01468 3.7e-13 sigC S Putative zinc-finger
EKFNCIHE_01469 2.3e-36 ylaE
EKFNCIHE_01470 6.7e-24 S Family of unknown function (DUF5325)
EKFNCIHE_01471 0.0 typA T GTP-binding protein TypA
EKFNCIHE_01472 6.6e-48 ylaH S YlaH-like protein
EKFNCIHE_01473 1.4e-33 ylaI S protein conserved in bacteria
EKFNCIHE_01474 2.6e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EKFNCIHE_01475 6e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
EKFNCIHE_01476 8.5e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EKFNCIHE_01477 1.3e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
EKFNCIHE_01478 8.7e-44 ylaN S Belongs to the UPF0358 family
EKFNCIHE_01479 1.9e-212 ftsW D Belongs to the SEDS family
EKFNCIHE_01480 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EKFNCIHE_01481 1.7e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EKFNCIHE_01482 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EKFNCIHE_01483 1.2e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EKFNCIHE_01484 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EKFNCIHE_01485 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EKFNCIHE_01486 1.9e-50 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EKFNCIHE_01487 2e-163 ctaG S cytochrome c oxidase
EKFNCIHE_01488 3.2e-59 ylbA S YugN-like family
EKFNCIHE_01489 2.2e-73 ylbB T COG0517 FOG CBS domain
EKFNCIHE_01490 2.3e-198 ylbC S protein with SCP PR1 domains
EKFNCIHE_01491 2.1e-54 ylbD S Putative coat protein
EKFNCIHE_01492 8.8e-37 ylbE S YlbE-like protein
EKFNCIHE_01493 1.2e-71 ylbF S Belongs to the UPF0342 family
EKFNCIHE_01494 5.5e-43 ylbG S UPF0298 protein
EKFNCIHE_01496 2.7e-97 rsmD 2.1.1.171 L Methyltransferase
EKFNCIHE_01497 4e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EKFNCIHE_01498 6.3e-216 ylbJ S Sporulation integral membrane protein YlbJ
EKFNCIHE_01499 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
EKFNCIHE_01500 1.6e-188 ylbL T Belongs to the peptidase S16 family
EKFNCIHE_01501 5.6e-228 ylbM S Belongs to the UPF0348 family
EKFNCIHE_01502 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
EKFNCIHE_01503 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EKFNCIHE_01504 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EKFNCIHE_01505 2e-88 ylbP K n-acetyltransferase
EKFNCIHE_01506 3.6e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EKFNCIHE_01507 2.6e-305 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EKFNCIHE_01508 1.2e-77 mraZ K Belongs to the MraZ family
EKFNCIHE_01509 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EKFNCIHE_01510 2.9e-52 ftsL D Essential cell division protein
EKFNCIHE_01511 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
EKFNCIHE_01512 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
EKFNCIHE_01513 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EKFNCIHE_01514 1.1e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EKFNCIHE_01515 6.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EKFNCIHE_01516 2.2e-185 spoVE D Belongs to the SEDS family
EKFNCIHE_01517 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EKFNCIHE_01518 1.8e-167 murB 1.3.1.98 M cell wall formation
EKFNCIHE_01519 4.8e-132 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EKFNCIHE_01520 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EKFNCIHE_01521 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EKFNCIHE_01522 0.0 bpr O COG1404 Subtilisin-like serine proteases
EKFNCIHE_01523 3.7e-160 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EKFNCIHE_01524 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFNCIHE_01525 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFNCIHE_01526 7.9e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EKFNCIHE_01527 8.7e-249 argE 3.5.1.16 E Acetylornithine deacetylase
EKFNCIHE_01528 2.2e-38 ylmC S sporulation protein
EKFNCIHE_01529 3.7e-159 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
EKFNCIHE_01530 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EKFNCIHE_01531 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EKFNCIHE_01532 5.2e-41 yggT S membrane
EKFNCIHE_01533 6.1e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
EKFNCIHE_01534 8.9e-68 divIVA D Cell division initiation protein
EKFNCIHE_01535 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EKFNCIHE_01536 1.2e-61 dksA T COG1734 DnaK suppressor protein
EKFNCIHE_01537 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EKFNCIHE_01538 1.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EKFNCIHE_01539 1.4e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EKFNCIHE_01540 3e-232 pyrP F Xanthine uracil
EKFNCIHE_01541 5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EKFNCIHE_01542 3.6e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EKFNCIHE_01543 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EKFNCIHE_01544 0.0 carB 6.3.5.5 F Belongs to the CarB family
EKFNCIHE_01545 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EKFNCIHE_01546 2.5e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EKFNCIHE_01547 2.1e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EKFNCIHE_01548 6.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EKFNCIHE_01550 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
EKFNCIHE_01551 1.1e-176 cysP P phosphate transporter
EKFNCIHE_01552 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
EKFNCIHE_01553 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
EKFNCIHE_01554 2.2e-142 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
EKFNCIHE_01555 1.6e-143 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
EKFNCIHE_01556 5.5e-78 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
EKFNCIHE_01557 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EKFNCIHE_01558 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
EKFNCIHE_01559 8.5e-154 yloC S stress-induced protein
EKFNCIHE_01560 1.5e-40 ylzA S Belongs to the UPF0296 family
EKFNCIHE_01561 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EKFNCIHE_01562 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EKFNCIHE_01563 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EKFNCIHE_01564 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EKFNCIHE_01565 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EKFNCIHE_01566 6.8e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EKFNCIHE_01567 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EKFNCIHE_01568 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EKFNCIHE_01569 2.3e-139 stp 3.1.3.16 T phosphatase
EKFNCIHE_01570 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
EKFNCIHE_01571 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EKFNCIHE_01572 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EKFNCIHE_01573 1.3e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
EKFNCIHE_01574 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EKFNCIHE_01575 5.5e-59 asp S protein conserved in bacteria
EKFNCIHE_01576 4.9e-304 yloV S kinase related to dihydroxyacetone kinase
EKFNCIHE_01577 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
EKFNCIHE_01578 1.3e-154 sdaAA 4.3.1.17 E L-serine dehydratase
EKFNCIHE_01579 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EKFNCIHE_01580 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EKFNCIHE_01581 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EKFNCIHE_01582 7.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EKFNCIHE_01583 4.6e-129 IQ reductase
EKFNCIHE_01584 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EKFNCIHE_01585 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EKFNCIHE_01586 0.0 smc D Required for chromosome condensation and partitioning
EKFNCIHE_01587 1.1e-173 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EKFNCIHE_01588 3e-139 S Phosphotransferase enzyme family
EKFNCIHE_01589 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EKFNCIHE_01590 7.6e-223 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EKFNCIHE_01591 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EKFNCIHE_01592 1.7e-35 ylqC S Belongs to the UPF0109 family
EKFNCIHE_01593 1.3e-61 ylqD S YlqD protein
EKFNCIHE_01594 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EKFNCIHE_01595 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EKFNCIHE_01596 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EKFNCIHE_01597 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EKFNCIHE_01598 1.5e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EKFNCIHE_01599 6.6e-304 ylqG
EKFNCIHE_01600 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
EKFNCIHE_01601 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EKFNCIHE_01602 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EKFNCIHE_01603 1.6e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
EKFNCIHE_01604 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EKFNCIHE_01605 2.2e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EKFNCIHE_01606 7.2e-172 xerC L tyrosine recombinase XerC
EKFNCIHE_01607 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EKFNCIHE_01608 4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EKFNCIHE_01609 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EKFNCIHE_01610 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EKFNCIHE_01611 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
EKFNCIHE_01612 1.3e-30 fliE N Flagellar hook-basal body
EKFNCIHE_01613 1.4e-263 fliF N The M ring may be actively involved in energy transduction
EKFNCIHE_01614 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EKFNCIHE_01615 1.5e-87 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
EKFNCIHE_01616 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EKFNCIHE_01617 2e-71 fliJ N Flagellar biosynthesis chaperone
EKFNCIHE_01618 1.3e-47 ylxF S MgtE intracellular N domain
EKFNCIHE_01619 7.5e-202 fliK N Flagellar hook-length control protein
EKFNCIHE_01620 2.4e-72 flgD N Flagellar basal body rod modification protein
EKFNCIHE_01621 5.7e-138 flgG N Flagellar basal body rod
EKFNCIHE_01622 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
EKFNCIHE_01623 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EKFNCIHE_01624 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EKFNCIHE_01625 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
EKFNCIHE_01626 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
EKFNCIHE_01627 2.2e-109 fliP N Plays a role in the flagellum-specific transport system
EKFNCIHE_01628 2e-37 fliQ N Role in flagellar biosynthesis
EKFNCIHE_01629 5.2e-131 fliR N Flagellar biosynthetic protein FliR
EKFNCIHE_01630 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EKFNCIHE_01631 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EKFNCIHE_01632 2.2e-191 flhF N Flagellar biosynthesis regulator FlhF
EKFNCIHE_01633 2.4e-156 flhG D Belongs to the ParA family
EKFNCIHE_01634 2.5e-192 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EKFNCIHE_01635 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
EKFNCIHE_01636 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
EKFNCIHE_01637 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EKFNCIHE_01638 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EKFNCIHE_01639 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFNCIHE_01640 8e-50 ylxL
EKFNCIHE_01641 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
EKFNCIHE_01642 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EKFNCIHE_01643 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EKFNCIHE_01644 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EKFNCIHE_01645 1.4e-144 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EKFNCIHE_01646 2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
EKFNCIHE_01647 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EKFNCIHE_01648 5.9e-233 rasP M zinc metalloprotease
EKFNCIHE_01649 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EKFNCIHE_01650 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EKFNCIHE_01651 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
EKFNCIHE_01652 5.4e-206 nusA K Participates in both transcription termination and antitermination
EKFNCIHE_01653 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
EKFNCIHE_01654 1.8e-47 ylxQ J ribosomal protein
EKFNCIHE_01655 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EKFNCIHE_01656 3.9e-44 ylxP S protein conserved in bacteria
EKFNCIHE_01657 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EKFNCIHE_01658 8e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EKFNCIHE_01659 4.6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EKFNCIHE_01660 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EKFNCIHE_01661 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EKFNCIHE_01662 2e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
EKFNCIHE_01663 1.2e-233 pepR S Belongs to the peptidase M16 family
EKFNCIHE_01664 2.6e-42 ymxH S YlmC YmxH family
EKFNCIHE_01665 1e-159 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
EKFNCIHE_01666 5.7e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EKFNCIHE_01667 4.9e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EKFNCIHE_01668 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
EKFNCIHE_01669 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EKFNCIHE_01670 2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EKFNCIHE_01671 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
EKFNCIHE_01672 6.3e-31 S YlzJ-like protein
EKFNCIHE_01673 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EKFNCIHE_01674 1.2e-132 ymfC K Transcriptional regulator
EKFNCIHE_01675 3e-227 ymfD EGP Major facilitator Superfamily
EKFNCIHE_01676 2.1e-76 K helix_turn_helix multiple antibiotic resistance protein
EKFNCIHE_01677 0.0 ydgH S drug exporters of the RND superfamily
EKFNCIHE_01678 8.9e-237 ymfF S Peptidase M16
EKFNCIHE_01679 3.5e-241 ymfH S zinc protease
EKFNCIHE_01680 1.2e-126 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EKFNCIHE_01681 2.2e-41 ymfJ S Protein of unknown function (DUF3243)
EKFNCIHE_01682 1e-142 ymfK S Protein of unknown function (DUF3388)
EKFNCIHE_01683 4.1e-124 ymfM S protein conserved in bacteria
EKFNCIHE_01684 1.4e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EKFNCIHE_01685 9.3e-231 cinA 3.5.1.42 S Belongs to the CinA family
EKFNCIHE_01686 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EKFNCIHE_01687 1.1e-193 pbpX V Beta-lactamase
EKFNCIHE_01688 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
EKFNCIHE_01689 4.9e-153 ymdB S protein conserved in bacteria
EKFNCIHE_01690 1.2e-36 spoVS S Stage V sporulation protein S
EKFNCIHE_01691 4.5e-194 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EKFNCIHE_01692 2.6e-214 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EKFNCIHE_01693 6.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EKFNCIHE_01694 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EKFNCIHE_01695 1.7e-88 cotE S Spore coat protein
EKFNCIHE_01696 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EKFNCIHE_01697 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EKFNCIHE_01698 2.4e-33
EKFNCIHE_01701 1.3e-128 pksB 3.1.2.6 S Polyketide biosynthesis
EKFNCIHE_01702 2.4e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EKFNCIHE_01703 1.1e-183 pksD Q Acyl transferase domain
EKFNCIHE_01704 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EKFNCIHE_01705 5.5e-34 acpK IQ Phosphopantetheine attachment site
EKFNCIHE_01706 5.3e-242 pksG 2.3.3.10 I synthase
EKFNCIHE_01707 1.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
EKFNCIHE_01708 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
EKFNCIHE_01709 0.0 rhiB IQ polyketide synthase
EKFNCIHE_01710 0.0 Q Polyketide synthase of type I
EKFNCIHE_01711 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
EKFNCIHE_01712 0.0 dhbF IQ polyketide synthase
EKFNCIHE_01713 0.0 pks13 HQ Beta-ketoacyl synthase
EKFNCIHE_01714 1.3e-229 cypA C Cytochrome P450
EKFNCIHE_01715 1.9e-77 nucB M Deoxyribonuclease NucA/NucB
EKFNCIHE_01716 3.6e-118 yoaK S Membrane
EKFNCIHE_01717 3.5e-61 ymzB
EKFNCIHE_01718 1.7e-254 aprX O Belongs to the peptidase S8 family
EKFNCIHE_01719 3e-125 ymaC S Replication protein
EKFNCIHE_01720 6e-79 ymaD O redox protein, regulator of disulfide bond formation
EKFNCIHE_01721 2.6e-53 ebrB P Small Multidrug Resistance protein
EKFNCIHE_01722 2.6e-47 ebrA P Small Multidrug Resistance protein
EKFNCIHE_01724 9.2e-47 ymaF S YmaF family
EKFNCIHE_01725 4.8e-171 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EKFNCIHE_01726 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EKFNCIHE_01727 1.8e-41
EKFNCIHE_01728 1.8e-20 ymzA
EKFNCIHE_01729 3.9e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
EKFNCIHE_01730 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKFNCIHE_01731 4.7e-185 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKFNCIHE_01732 1.6e-85 ymaB S MutT family
EKFNCIHE_01733 1.6e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EKFNCIHE_01734 1.3e-176 spoVK O stage V sporulation protein K
EKFNCIHE_01735 7.2e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EKFNCIHE_01736 2.4e-242 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EKFNCIHE_01737 4.3e-68 glnR K transcriptional
EKFNCIHE_01738 4.1e-261 glnA 6.3.1.2 E glutamine synthetase
EKFNCIHE_01739 4.3e-208 mrjp G Major royal jelly protein
EKFNCIHE_01740 4.9e-249 xynT G MFS/sugar transport protein
EKFNCIHE_01741 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
EKFNCIHE_01742 7.3e-206 xylR GK ROK family
EKFNCIHE_01743 1.2e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
EKFNCIHE_01744 6e-285 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
EKFNCIHE_01745 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
EKFNCIHE_01749 3.1e-184 adhP 1.1.1.1 C alcohol dehydrogenase
EKFNCIHE_01750 1e-09
EKFNCIHE_01752 2.1e-131 yoaP 3.1.3.18 K YoaP-like
EKFNCIHE_01753 1.6e-99 J Acetyltransferase (GNAT) domain
EKFNCIHE_01754 2.8e-114 ynaE S Domain of unknown function (DUF3885)
EKFNCIHE_01755 3.9e-201 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFNCIHE_01756 4.5e-117 AA10,CBM73 S Pfam:Chitin_bind_3
EKFNCIHE_01759 8.7e-93 yvgO
EKFNCIHE_01761 0.0 yobO M Pectate lyase superfamily protein
EKFNCIHE_01762 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
EKFNCIHE_01763 1e-140 yndL S Replication protein
EKFNCIHE_01764 9.1e-08
EKFNCIHE_01765 1.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
EKFNCIHE_01766 1.2e-71 yndM S Protein of unknown function (DUF2512)
EKFNCIHE_01767 2.1e-12 yoaW
EKFNCIHE_01768 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EKFNCIHE_01769 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EKFNCIHE_01770 3.5e-112 yneB L resolvase
EKFNCIHE_01771 9.8e-33 ynzC S UPF0291 protein
EKFNCIHE_01772 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EKFNCIHE_01773 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
EKFNCIHE_01774 2.3e-28 yneF S UPF0154 protein
EKFNCIHE_01775 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
EKFNCIHE_01776 1.7e-125 ccdA O cytochrome c biogenesis protein
EKFNCIHE_01777 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
EKFNCIHE_01778 9.6e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
EKFNCIHE_01779 5.5e-74 yneK S Protein of unknown function (DUF2621)
EKFNCIHE_01780 1.4e-62 hspX O Spore coat protein
EKFNCIHE_01781 2.3e-19 sspP S Belongs to the SspP family
EKFNCIHE_01782 7.5e-15 sspO S Belongs to the SspO family
EKFNCIHE_01783 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EKFNCIHE_01784 1.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EKFNCIHE_01787 7.1e-18 tlp S Belongs to the Tlp family
EKFNCIHE_01788 8.3e-75 yneP S Thioesterase-like superfamily
EKFNCIHE_01789 1.4e-52 yneQ
EKFNCIHE_01790 1.1e-49 yneR S Belongs to the HesB IscA family
EKFNCIHE_01791 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EKFNCIHE_01792 1.5e-68 yccU S CoA-binding protein
EKFNCIHE_01793 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EKFNCIHE_01794 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EKFNCIHE_01795 6e-13
EKFNCIHE_01796 5.1e-41 ynfC
EKFNCIHE_01797 1.2e-245 agcS E Sodium alanine symporter
EKFNCIHE_01798 5.7e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
EKFNCIHE_01799 6.5e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
EKFNCIHE_01800 1.5e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
EKFNCIHE_01801 6e-210 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
EKFNCIHE_01802 1.8e-145 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFNCIHE_01803 1e-179 kdgR_1 K transcriptional
EKFNCIHE_01804 1.4e-39 exuT G Sugar (and other) transporter
EKFNCIHE_01805 5.4e-155 yndG S DoxX-like family
EKFNCIHE_01806 5.6e-80 yndH S Domain of unknown function (DUF4166)
EKFNCIHE_01807 1.7e-296 yndJ S YndJ-like protein
EKFNCIHE_01808 2.1e-33 S Platelet-activating factor acetylhydrolase, isoform II
EKFNCIHE_01809 2.9e-17 S Platelet-activating factor acetylhydrolase, isoform II
EKFNCIHE_01810 1.3e-284 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
EKFNCIHE_01811 1.2e-49 S Domain of unknown function (DUF4870)
EKFNCIHE_01812 3.1e-227 T PhoQ Sensor
EKFNCIHE_01813 4.6e-126 T Transcriptional regulatory protein, C terminal
EKFNCIHE_01814 2.4e-250 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
EKFNCIHE_01815 4.7e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
EKFNCIHE_01816 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFNCIHE_01817 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFNCIHE_01818 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFNCIHE_01819 1.3e-216 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EKFNCIHE_01820 2.9e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EKFNCIHE_01821 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EKFNCIHE_01822 9.9e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EKFNCIHE_01823 4.2e-251 yxjC EG COG2610 H gluconate symporter and related permeases
EKFNCIHE_01824 5.6e-217 bioI 1.14.14.46 C Cytochrome P450
EKFNCIHE_01825 3.7e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EKFNCIHE_01826 9.2e-127 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EKFNCIHE_01827 1.5e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EKFNCIHE_01828 3.3e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EKFNCIHE_01829 1.5e-143 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EKFNCIHE_01830 1.2e-67 yngA S membrane
EKFNCIHE_01831 7.5e-158 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EKFNCIHE_01832 3.2e-104 yngC S SNARE associated Golgi protein
EKFNCIHE_01833 2.2e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EKFNCIHE_01834 1.5e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
EKFNCIHE_01835 6.8e-167 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
EKFNCIHE_01836 6e-29 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
EKFNCIHE_01837 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
EKFNCIHE_01838 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EKFNCIHE_01839 5.4e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
EKFNCIHE_01840 7.3e-302 yngK T Glycosyl hydrolase-like 10
EKFNCIHE_01841 1.6e-64 yngL S Protein of unknown function (DUF1360)
EKFNCIHE_01842 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
EKFNCIHE_01843 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFNCIHE_01844 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFNCIHE_01845 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFNCIHE_01846 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFNCIHE_01847 1.9e-267 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
EKFNCIHE_01848 7.8e-185 yoxA 5.1.3.3 G Aldose 1-epimerase
EKFNCIHE_01849 6.7e-246 yoeA V MATE efflux family protein
EKFNCIHE_01850 2.9e-96 yoeB S IseA DL-endopeptidase inhibitor
EKFNCIHE_01852 3.5e-97 L Integrase
EKFNCIHE_01853 1.8e-34 yoeD G Helix-turn-helix domain
EKFNCIHE_01854 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
EKFNCIHE_01855 5.2e-199 ybcL EGP Major facilitator Superfamily
EKFNCIHE_01856 1.8e-50 ybzH K Helix-turn-helix domain
EKFNCIHE_01857 1.7e-13 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EKFNCIHE_01858 1.2e-152 gltR1 K Transcriptional regulator
EKFNCIHE_01859 1.1e-183 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EKFNCIHE_01860 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EKFNCIHE_01861 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
EKFNCIHE_01862 4.5e-150 gltC K Transcriptional regulator
EKFNCIHE_01863 6.2e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EKFNCIHE_01864 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKFNCIHE_01865 3.9e-60 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EKFNCIHE_01866 1.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFNCIHE_01867 1.6e-38 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EKFNCIHE_01868 6.4e-134 yoxB
EKFNCIHE_01869 4.8e-203 yoaB EGP Major facilitator Superfamily
EKFNCIHE_01870 1e-265 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
EKFNCIHE_01871 9.6e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKFNCIHE_01872 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EKFNCIHE_01873 1.5e-95 hpr K helix_turn_helix multiple antibiotic resistance protein
EKFNCIHE_01874 7.4e-43
EKFNCIHE_01875 1.9e-130 IQ Enoyl-(Acyl carrier protein) reductase
EKFNCIHE_01876 1.3e-60 ykvN K Transcriptional regulator
EKFNCIHE_01877 1.2e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
EKFNCIHE_01878 4.3e-132 yobQ K helix_turn_helix, arabinose operon control protein
EKFNCIHE_01879 1.1e-93 yobS K Transcriptional regulator
EKFNCIHE_01880 2.7e-134 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
EKFNCIHE_01881 7.1e-92 yobW
EKFNCIHE_01882 1.7e-54 czrA K transcriptional
EKFNCIHE_01883 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EKFNCIHE_01884 3.6e-91 yozB S membrane
EKFNCIHE_01885 3.4e-138 yocB J Protein required for attachment to host cells
EKFNCIHE_01886 1.6e-93 yocC
EKFNCIHE_01887 2.4e-186 yocD 3.4.17.13 V peptidase S66
EKFNCIHE_01889 6.5e-114 yocH CBM50 M COG1388 FOG LysM repeat
EKFNCIHE_01890 0.0 recQ 3.6.4.12 L DNA helicase
EKFNCIHE_01891 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EKFNCIHE_01893 9.5e-54 dksA T general stress protein
EKFNCIHE_01894 1e-09 yocL
EKFNCIHE_01895 7.5e-09
EKFNCIHE_01896 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
EKFNCIHE_01897 3.8e-44 yozN
EKFNCIHE_01898 8.5e-37 yocN
EKFNCIHE_01899 2.4e-56 yozO S Bacterial PH domain
EKFNCIHE_01901 3.6e-31 yozC
EKFNCIHE_01902 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
EKFNCIHE_01903 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
EKFNCIHE_01904 2.1e-165 sodA 1.15.1.1 P Superoxide dismutase
EKFNCIHE_01905 7.4e-234 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EKFNCIHE_01906 2.5e-159 yocS S -transporter
EKFNCIHE_01907 1.1e-138 S Metallo-beta-lactamase superfamily
EKFNCIHE_01908 5.5e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EKFNCIHE_01909 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EKFNCIHE_01910 0.0 yojO P Von Willebrand factor
EKFNCIHE_01911 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
EKFNCIHE_01912 2.1e-108 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EKFNCIHE_01913 4.4e-225 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EKFNCIHE_01914 6.9e-223 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
EKFNCIHE_01915 1.7e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EKFNCIHE_01917 4.7e-236 norM V Multidrug efflux pump
EKFNCIHE_01918 2.2e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EKFNCIHE_01919 5.6e-126 yojG S deacetylase
EKFNCIHE_01920 3.7e-60 yojF S Protein of unknown function (DUF1806)
EKFNCIHE_01921 1.4e-22
EKFNCIHE_01922 1.1e-161 rarD S -transporter
EKFNCIHE_01923 7.3e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
EKFNCIHE_01925 5.9e-67 yodA S tautomerase
EKFNCIHE_01926 2.3e-68 yoaQ S Evidence 4 Homologs of previously reported genes of
EKFNCIHE_01927 3e-56 yodB K transcriptional
EKFNCIHE_01928 1.7e-105 yodC C nitroreductase
EKFNCIHE_01929 6.3e-108 mhqD S Carboxylesterase
EKFNCIHE_01930 1e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
EKFNCIHE_01931 1.4e-19 S Protein of unknown function (DUF3311)
EKFNCIHE_01932 3.6e-253 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKFNCIHE_01933 1.7e-279 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
EKFNCIHE_01934 1.5e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EKFNCIHE_01935 2.6e-132 yydK K Transcriptional regulator
EKFNCIHE_01936 5.7e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
EKFNCIHE_01937 2.8e-128 yodH Q Methyltransferase
EKFNCIHE_01938 6.5e-22 yodI
EKFNCIHE_01939 8.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EKFNCIHE_01940 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
EKFNCIHE_01942 3.3e-55 yodL S YodL-like
EKFNCIHE_01943 2.3e-102 yodM 3.6.1.27 I Acid phosphatase homologues
EKFNCIHE_01944 6.2e-24 yozD S YozD-like protein
EKFNCIHE_01946 1.7e-125 yodN
EKFNCIHE_01947 9.1e-36 yozE S Belongs to the UPF0346 family
EKFNCIHE_01948 9.2e-46 yokU S YokU-like protein, putative antitoxin
EKFNCIHE_01949 3.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
EKFNCIHE_01950 1.9e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
EKFNCIHE_01951 9e-253 yodQ 3.5.1.16 E Acetylornithine deacetylase
EKFNCIHE_01952 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EKFNCIHE_01953 2.2e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EKFNCIHE_01954 1.1e-245 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EKFNCIHE_01955 2e-63 yosT L Bacterial transcription activator, effector binding domain
EKFNCIHE_01957 1.4e-144 yiiD K acetyltransferase
EKFNCIHE_01958 2e-241 cgeD M maturation of the outermost layer of the spore
EKFNCIHE_01959 1.2e-40 cgeC
EKFNCIHE_01960 7.8e-52 cgeA
EKFNCIHE_01961 3.4e-164 cgeB S Spore maturation protein
EKFNCIHE_01962 1.5e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
EKFNCIHE_01963 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
EKFNCIHE_01969 1.7e-77
EKFNCIHE_01970 6.1e-19 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
EKFNCIHE_01971 2.6e-08
EKFNCIHE_01974 3.1e-75 yoqH M LysM domain
EKFNCIHE_01975 5e-207 S aspartate phosphatase
EKFNCIHE_01978 4.8e-113 3.4.24.40 S amine dehydrogenase activity
EKFNCIHE_01980 2.6e-08 S Domain of unknown function (DUF4879)
EKFNCIHE_01981 7e-24
EKFNCIHE_01982 6.6e-30 S Acetyltransferase (GNAT) domain
EKFNCIHE_01983 1.5e-87 yokK S SMI1 / KNR4 family
EKFNCIHE_01984 7.5e-53 S SMI1-KNR4 cell-wall
EKFNCIHE_01985 2.8e-289 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EKFNCIHE_01986 2.7e-77 yokH G SMI1 / KNR4 family
EKFNCIHE_01988 4.2e-303 yokA L Recombinase
EKFNCIHE_01989 2.6e-103 4.2.1.115 GM Polysaccharide biosynthesis protein
EKFNCIHE_01990 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
EKFNCIHE_01991 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKFNCIHE_01992 1.4e-66 ypoP K transcriptional
EKFNCIHE_01993 1.8e-96 ypmS S protein conserved in bacteria
EKFNCIHE_01994 6.4e-134 ypmR E GDSL-like Lipase/Acylhydrolase
EKFNCIHE_01995 4.3e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EKFNCIHE_01996 4.1e-37 ypmP S Protein of unknown function (DUF2535)
EKFNCIHE_01997 3.7e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EKFNCIHE_01998 8.3e-174 pspF K Transcriptional regulator
EKFNCIHE_01999 1.6e-109 hlyIII S protein, Hemolysin III
EKFNCIHE_02000 6.1e-114 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EKFNCIHE_02001 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EKFNCIHE_02002 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EKFNCIHE_02003 8.5e-113 ypjP S YpjP-like protein
EKFNCIHE_02004 1.1e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
EKFNCIHE_02005 1.1e-74 yphP S Belongs to the UPF0403 family
EKFNCIHE_02006 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EKFNCIHE_02007 4.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
EKFNCIHE_02008 3.1e-99 ypgQ S phosphohydrolase
EKFNCIHE_02009 7.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
EKFNCIHE_02010 1.3e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EKFNCIHE_02011 1.1e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EKFNCIHE_02012 1e-30 cspD K Cold-shock protein
EKFNCIHE_02013 1.3e-11 degR
EKFNCIHE_02014 1.2e-36 S Protein of unknown function (DUF2564)
EKFNCIHE_02015 1.5e-28 ypeQ S Zinc-finger
EKFNCIHE_02016 9.1e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
EKFNCIHE_02017 2e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EKFNCIHE_02018 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
EKFNCIHE_02020 3.5e-163 polA 2.7.7.7 L 5'3' exonuclease
EKFNCIHE_02022 2.2e-38 ypbS S Protein of unknown function (DUF2533)
EKFNCIHE_02023 0.0 ypbR S Dynamin family
EKFNCIHE_02024 1.1e-89 ypbQ S protein conserved in bacteria
EKFNCIHE_02025 6.1e-202 bcsA Q Naringenin-chalcone synthase
EKFNCIHE_02026 6.6e-105 J Acetyltransferase (GNAT) domain
EKFNCIHE_02027 6e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
EKFNCIHE_02029 8.7e-22 ydfR S Protein of unknown function (DUF421)
EKFNCIHE_02030 9.8e-33 ydfR S Protein of unknown function (DUF421)
EKFNCIHE_02031 1.9e-98 yrdC 3.5.1.19 Q Isochorismatase family
EKFNCIHE_02033 1.5e-72 S Protein of unknown function (DUF3800)
EKFNCIHE_02034 1.6e-25 K Helix-turn-helix domain
EKFNCIHE_02036 1.4e-22
EKFNCIHE_02037 2e-86 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
EKFNCIHE_02038 2.2e-69 S N-acetylmuramoyl-L-alanine amidase activity
EKFNCIHE_02039 3.8e-59 S Pfam:Phage_holin_4_1
EKFNCIHE_02041 1.2e-08
EKFNCIHE_02042 2.5e-99
EKFNCIHE_02043 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
EKFNCIHE_02044 1.5e-228 NU Prophage endopeptidase tail
EKFNCIHE_02045 2.5e-102 S Phage tail protein
EKFNCIHE_02046 0.0 D phage tail tape measure protein
EKFNCIHE_02048 5.1e-81 S Phage tail tube protein
EKFNCIHE_02050 7.4e-49 S Bacteriophage HK97-gp10, putative tail-component
EKFNCIHE_02051 2.9e-40 S Phage head-tail joining protein
EKFNCIHE_02052 4.5e-38 S Phage gp6-like head-tail connector protein
EKFNCIHE_02053 3.3e-23
EKFNCIHE_02054 6.6e-155 gp36 S capsid protein
EKFNCIHE_02055 1.5e-83 S peptidase activity
EKFNCIHE_02056 4.2e-170 S Phage portal protein
EKFNCIHE_02057 1.2e-300 S Terminase
EKFNCIHE_02058 2.2e-77 L phage terminase small subunit
EKFNCIHE_02062 1.4e-17 K Transcriptional regulator
EKFNCIHE_02064 4.6e-13 K Transcriptional regulator
EKFNCIHE_02066 7.8e-67 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EKFNCIHE_02072 3.4e-21 yqaO S Phage-like element PBSX protein XtrA
EKFNCIHE_02074 2.2e-59 rusA L Endodeoxyribonuclease RusA
EKFNCIHE_02076 6.3e-118 xkdC L IstB-like ATP binding protein
EKFNCIHE_02077 2.1e-78 3.1.3.16 L DnaD domain protein
EKFNCIHE_02079 1.7e-61 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
EKFNCIHE_02080 7.3e-100
EKFNCIHE_02084 5.8e-87
EKFNCIHE_02085 8.5e-43 S Phage regulatory protein Rha (Phage_pRha)
EKFNCIHE_02086 1.3e-32
EKFNCIHE_02087 2.7e-16 K Helix-turn-helix XRE-family like proteins
EKFNCIHE_02088 3.6e-139 L Belongs to the 'phage' integrase family
EKFNCIHE_02089 3.2e-234 pbuX F xanthine
EKFNCIHE_02090 3.1e-96 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EKFNCIHE_02091 1.3e-290 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EKFNCIHE_02092 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
EKFNCIHE_02094 6.6e-22 S YpzG-like protein
EKFNCIHE_02095 2.7e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EKFNCIHE_02096 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EKFNCIHE_02097 1.1e-98 ypsA S Belongs to the UPF0398 family
EKFNCIHE_02098 9.9e-33 cotD S Inner spore coat protein D
EKFNCIHE_02100 1.6e-219 yprB L RNase_H superfamily
EKFNCIHE_02101 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EKFNCIHE_02102 1e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
EKFNCIHE_02103 2.1e-70 hspX O Belongs to the small heat shock protein (HSP20) family
EKFNCIHE_02104 2.1e-49 yppG S YppG-like protein
EKFNCIHE_02106 3.3e-11 yppE S Bacterial domain of unknown function (DUF1798)
EKFNCIHE_02109 3.4e-188 yppC S Protein of unknown function (DUF2515)
EKFNCIHE_02110 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EKFNCIHE_02111 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EKFNCIHE_02112 5.7e-91 ypoC
EKFNCIHE_02113 2.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EKFNCIHE_02114 3e-130 dnaD L DNA replication protein DnaD
EKFNCIHE_02115 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
EKFNCIHE_02116 6.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EKFNCIHE_02117 1.5e-80 ypmB S protein conserved in bacteria
EKFNCIHE_02118 6.7e-23 ypmA S Protein of unknown function (DUF4264)
EKFNCIHE_02119 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EKFNCIHE_02120 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EKFNCIHE_02121 7.2e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EKFNCIHE_02122 1.6e-146 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EKFNCIHE_02123 1.6e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EKFNCIHE_02124 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EKFNCIHE_02125 2.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
EKFNCIHE_02126 1.9e-132 bshB1 S proteins, LmbE homologs
EKFNCIHE_02127 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
EKFNCIHE_02128 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EKFNCIHE_02129 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
EKFNCIHE_02130 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
EKFNCIHE_02131 2.6e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
EKFNCIHE_02132 9.5e-141 ypjB S sporulation protein
EKFNCIHE_02133 3.2e-104 ypjA S membrane
EKFNCIHE_02134 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
EKFNCIHE_02135 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
EKFNCIHE_02136 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
EKFNCIHE_02137 3.2e-77 ypiF S Protein of unknown function (DUF2487)
EKFNCIHE_02138 2.1e-99 ypiB S Belongs to the UPF0302 family
EKFNCIHE_02139 3.5e-233 S COG0457 FOG TPR repeat
EKFNCIHE_02140 8.1e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EKFNCIHE_02141 3.3e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EKFNCIHE_02142 6.4e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EKFNCIHE_02143 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EKFNCIHE_02144 1.2e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EKFNCIHE_02145 7.5e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
EKFNCIHE_02146 2.8e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EKFNCIHE_02147 4e-155 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EKFNCIHE_02148 1.9e-289 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EKFNCIHE_02149 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EKFNCIHE_02150 1.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EKFNCIHE_02151 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EKFNCIHE_02152 1.1e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
EKFNCIHE_02153 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EKFNCIHE_02154 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EKFNCIHE_02155 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EKFNCIHE_02156 1.2e-135 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EKFNCIHE_02157 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EKFNCIHE_02158 2.1e-100 folE 3.5.4.16 H GTP cyclohydrolase
EKFNCIHE_02159 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EKFNCIHE_02160 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EKFNCIHE_02161 3.1e-133 yphF
EKFNCIHE_02162 3.3e-16 yphE S Protein of unknown function (DUF2768)
EKFNCIHE_02163 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EKFNCIHE_02164 4.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EKFNCIHE_02165 7.2e-104 yphA
EKFNCIHE_02166 4.7e-08 S YpzI-like protein
EKFNCIHE_02167 1.7e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EKFNCIHE_02168 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
EKFNCIHE_02169 9.5e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EKFNCIHE_02170 1.4e-12 S Family of unknown function (DUF5359)
EKFNCIHE_02171 1.8e-60 ypfA M Flagellar protein YcgR
EKFNCIHE_02172 3e-251 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
EKFNCIHE_02173 3e-159 sleB 3.5.1.28 M Spore cortex-lytic enzyme
EKFNCIHE_02174 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
EKFNCIHE_02175 3.4e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
EKFNCIHE_02176 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
EKFNCIHE_02177 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EKFNCIHE_02178 1.3e-145 ypbG S Calcineurin-like phosphoesterase superfamily domain
EKFNCIHE_02179 5.7e-85 ypbF S Protein of unknown function (DUF2663)
EKFNCIHE_02180 1.3e-73 ypbE M Lysin motif
EKFNCIHE_02181 4e-99 ypbD S metal-dependent membrane protease
EKFNCIHE_02182 5.2e-270 recQ 3.6.4.12 L DNA helicase
EKFNCIHE_02183 1.1e-192 ypbB 5.1.3.1 S protein conserved in bacteria
EKFNCIHE_02184 3.6e-41 fer C Ferredoxin
EKFNCIHE_02185 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EKFNCIHE_02186 9.7e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKFNCIHE_02187 5.7e-192 rsiX
EKFNCIHE_02188 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
EKFNCIHE_02189 0.0 resE 2.7.13.3 T Histidine kinase
EKFNCIHE_02190 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFNCIHE_02191 1.2e-192 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EKFNCIHE_02192 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
EKFNCIHE_02193 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EKFNCIHE_02194 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EKFNCIHE_02195 1.3e-88 spmB S Spore maturation protein
EKFNCIHE_02196 2e-103 spmA S Spore maturation protein
EKFNCIHE_02197 6.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
EKFNCIHE_02198 3.8e-93 ypuI S Protein of unknown function (DUF3907)
EKFNCIHE_02199 1.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EKFNCIHE_02200 8.9e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EKFNCIHE_02202 2.9e-93 ypuF S Domain of unknown function (DUF309)
EKFNCIHE_02203 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKFNCIHE_02204 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EKFNCIHE_02205 3.2e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EKFNCIHE_02206 2.2e-111 ribE 2.5.1.9 H Riboflavin synthase
EKFNCIHE_02207 3.1e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EKFNCIHE_02208 6.4e-49 ypuD
EKFNCIHE_02209 8.4e-99 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EKFNCIHE_02210 1.2e-80 ccdC1 O Protein of unknown function (DUF1453)
EKFNCIHE_02211 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EKFNCIHE_02212 1.9e-153 ypuA S Secreted protein
EKFNCIHE_02213 3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EKFNCIHE_02214 3.2e-270 spoVAF EG Stage V sporulation protein AF
EKFNCIHE_02215 5.2e-110 spoVAEA S stage V sporulation protein
EKFNCIHE_02216 5e-57 spoVAEB S stage V sporulation protein
EKFNCIHE_02217 1.2e-188 spoVAD I Stage V sporulation protein AD
EKFNCIHE_02218 6e-79 spoVAC S stage V sporulation protein AC
EKFNCIHE_02219 5.1e-60 spoVAB S Stage V sporulation protein AB
EKFNCIHE_02220 4.8e-111 spoVAA S Stage V sporulation protein AA
EKFNCIHE_02221 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFNCIHE_02222 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EKFNCIHE_02223 6.6e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
EKFNCIHE_02224 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
EKFNCIHE_02225 5.5e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EKFNCIHE_02226 3.3e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EKFNCIHE_02227 2.8e-165 xerD L recombinase XerD
EKFNCIHE_02228 3.7e-37 S Protein of unknown function (DUF4227)
EKFNCIHE_02229 1.9e-80 fur P Belongs to the Fur family
EKFNCIHE_02230 1.2e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EKFNCIHE_02231 1e-31 yqkK
EKFNCIHE_02232 5.7e-22
EKFNCIHE_02233 4.2e-242 mleA 1.1.1.38 C malic enzyme
EKFNCIHE_02234 1.6e-239 mleN C Na H antiporter
EKFNCIHE_02235 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
EKFNCIHE_02236 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
EKFNCIHE_02237 1e-57 ansR K Transcriptional regulator
EKFNCIHE_02238 4e-220 yqxK 3.6.4.12 L DNA helicase
EKFNCIHE_02239 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
EKFNCIHE_02241 2e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
EKFNCIHE_02243 9e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
EKFNCIHE_02244 3.2e-39 yqkC S Protein of unknown function (DUF2552)
EKFNCIHE_02245 7.7e-61 yqkB S Belongs to the HesB IscA family
EKFNCIHE_02246 7.6e-172 yqkA K GrpB protein
EKFNCIHE_02247 9.6e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
EKFNCIHE_02248 8.7e-89 yqjY K acetyltransferase
EKFNCIHE_02249 6.1e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EKFNCIHE_02250 2.1e-55 S YolD-like protein
EKFNCIHE_02252 3.9e-185 yueF S transporter activity
EKFNCIHE_02254 2.8e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKFNCIHE_02255 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
EKFNCIHE_02256 1.4e-248 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
EKFNCIHE_02257 1e-139 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFNCIHE_02258 4e-173 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
EKFNCIHE_02259 4e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKFNCIHE_02260 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
EKFNCIHE_02261 3.7e-238 pksG 2.3.3.10 I synthase
EKFNCIHE_02262 2e-219 eryK 1.14.13.154 C Cytochrome P450
EKFNCIHE_02263 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EKFNCIHE_02264 0.0 Q Polyketide synthase of type I
EKFNCIHE_02265 0.0 pfaA Q Polyketide synthase of type I
EKFNCIHE_02266 0.0 pksJ Q Polyketide synthase of type I
EKFNCIHE_02267 0.0 Q Polyketide synthase of type I
EKFNCIHE_02268 0.0 1.1.1.320 Q Polyketide synthase of type I
EKFNCIHE_02269 0.0 pksJ Q Polyketide synthase of type I
EKFNCIHE_02270 1.1e-127 IQ reductase
EKFNCIHE_02271 1.7e-246 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EKFNCIHE_02274 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EKFNCIHE_02275 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
EKFNCIHE_02276 3e-159 K LysR substrate binding domain
EKFNCIHE_02277 1.6e-49 S GlpM protein
EKFNCIHE_02278 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EKFNCIHE_02279 1.3e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EKFNCIHE_02280 2.6e-10 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EKFNCIHE_02281 2.3e-170 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EKFNCIHE_02282 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EKFNCIHE_02283 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EKFNCIHE_02284 4.7e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EKFNCIHE_02285 2.4e-25 yqzJ
EKFNCIHE_02286 5e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EKFNCIHE_02287 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
EKFNCIHE_02288 1.1e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EKFNCIHE_02289 9.4e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
EKFNCIHE_02291 1.2e-94 yqjB S protein conserved in bacteria
EKFNCIHE_02292 1.4e-170 yqjA S Putative aromatic acid exporter C-terminal domain
EKFNCIHE_02293 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EKFNCIHE_02294 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
EKFNCIHE_02295 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
EKFNCIHE_02296 1e-75 yqiW S Belongs to the UPF0403 family
EKFNCIHE_02297 2.3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EKFNCIHE_02298 1.2e-188 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EKFNCIHE_02299 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EKFNCIHE_02300 1.1e-160 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EKFNCIHE_02301 1e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EKFNCIHE_02302 5.9e-205 buk 2.7.2.7 C Belongs to the acetokinase family
EKFNCIHE_02303 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
EKFNCIHE_02304 2.3e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
EKFNCIHE_02305 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
EKFNCIHE_02306 3.2e-34 yqzF S Protein of unknown function (DUF2627)
EKFNCIHE_02307 2.4e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EKFNCIHE_02308 2.7e-274 prpD 4.2.1.79 S 2-methylcitrate dehydratase
EKFNCIHE_02309 1.9e-203 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
EKFNCIHE_02310 5.3e-201 mmgC I acyl-CoA dehydrogenase
EKFNCIHE_02311 2.5e-155 hbdA 1.1.1.157 I Dehydrogenase
EKFNCIHE_02312 2.4e-212 mmgA 2.3.1.9 I Belongs to the thiolase family
EKFNCIHE_02313 8.1e-134 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EKFNCIHE_02314 2.3e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
EKFNCIHE_02315 4.2e-17
EKFNCIHE_02316 3.4e-101 ytaF P Probably functions as a manganese efflux pump
EKFNCIHE_02317 3.4e-112 K Protein of unknown function (DUF1232)
EKFNCIHE_02319 1.2e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EKFNCIHE_02322 4.1e-212 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EKFNCIHE_02323 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EKFNCIHE_02324 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
EKFNCIHE_02325 0.0 recN L May be involved in recombinational repair of damaged DNA
EKFNCIHE_02326 3.9e-78 argR K Regulates arginine biosynthesis genes
EKFNCIHE_02327 1.3e-154 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
EKFNCIHE_02328 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EKFNCIHE_02329 8.8e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EKFNCIHE_02330 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EKFNCIHE_02331 1.3e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EKFNCIHE_02332 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EKFNCIHE_02333 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EKFNCIHE_02334 8.1e-67 yqhY S protein conserved in bacteria
EKFNCIHE_02335 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EKFNCIHE_02336 4.6e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EKFNCIHE_02337 4.3e-62 spoIIIAH S SpoIIIAH-like protein
EKFNCIHE_02338 1.9e-116 spoIIIAG S stage III sporulation protein AG
EKFNCIHE_02339 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
EKFNCIHE_02340 6.3e-200 spoIIIAE S stage III sporulation protein AE
EKFNCIHE_02341 2.5e-41 spoIIIAD S Stage III sporulation protein AD
EKFNCIHE_02342 7.6e-29 spoIIIAC S stage III sporulation protein AC
EKFNCIHE_02343 1.6e-83 spoIIIAB S Stage III sporulation protein
EKFNCIHE_02344 2.1e-171 spoIIIAA S stage III sporulation protein AA
EKFNCIHE_02345 1.8e-36 yqhV S Protein of unknown function (DUF2619)
EKFNCIHE_02346 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EKFNCIHE_02347 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
EKFNCIHE_02348 3.7e-88 yqhR S Conserved membrane protein YqhR
EKFNCIHE_02349 8e-174 yqhQ S Protein of unknown function (DUF1385)
EKFNCIHE_02350 5.8e-62 yqhP
EKFNCIHE_02351 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
EKFNCIHE_02352 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EKFNCIHE_02353 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EKFNCIHE_02354 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
EKFNCIHE_02355 3.5e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EKFNCIHE_02356 3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EKFNCIHE_02357 2.8e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
EKFNCIHE_02358 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
EKFNCIHE_02359 5.5e-152 yqhG S Bacterial protein YqhG of unknown function
EKFNCIHE_02360 5.2e-23 sinI S Anti-repressor SinI
EKFNCIHE_02361 7.8e-55 sinR K transcriptional
EKFNCIHE_02362 4.7e-140 tasA S Cell division protein FtsN
EKFNCIHE_02363 1.9e-69 sipW 3.4.21.89 U Signal peptidase
EKFNCIHE_02364 2.7e-120 yqxM
EKFNCIHE_02365 3.2e-53 yqzG S Protein of unknown function (DUF3889)
EKFNCIHE_02366 2.3e-26 yqzE S YqzE-like protein
EKFNCIHE_02367 1e-60 S ComG operon protein 7
EKFNCIHE_02368 1.6e-64 comGF U Putative Competence protein ComGF
EKFNCIHE_02369 2.6e-20 comGE
EKFNCIHE_02370 5.8e-71 gspH NU Tfp pilus assembly protein FimT
EKFNCIHE_02371 8.9e-50 comGC U Required for transformation and DNA binding
EKFNCIHE_02372 4.6e-183 comGB NU COG1459 Type II secretory pathway, component PulF
EKFNCIHE_02373 1.7e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EKFNCIHE_02374 4.5e-185 corA P Mg2 transporter protein
EKFNCIHE_02375 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
EKFNCIHE_02376 6.5e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EKFNCIHE_02378 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
EKFNCIHE_02379 3.1e-37 yqgY S Protein of unknown function (DUF2626)
EKFNCIHE_02380 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
EKFNCIHE_02381 1.2e-19 yqgW S Protein of unknown function (DUF2759)
EKFNCIHE_02382 4.5e-49 yqgV S Thiamine-binding protein
EKFNCIHE_02383 1.1e-197 yqgU
EKFNCIHE_02384 2e-216 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
EKFNCIHE_02385 2.2e-179 glcK 2.7.1.2 G Glucokinase
EKFNCIHE_02386 1.5e-212 nhaC C Na H antiporter
EKFNCIHE_02387 4e-07 yqgO
EKFNCIHE_02388 4.6e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EKFNCIHE_02389 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EKFNCIHE_02390 1.2e-50 yqzD
EKFNCIHE_02391 1.1e-75 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EKFNCIHE_02392 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EKFNCIHE_02393 8e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EKFNCIHE_02394 2.9e-154 pstA P Phosphate transport system permease
EKFNCIHE_02395 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
EKFNCIHE_02396 8.4e-157 pstS P Phosphate
EKFNCIHE_02397 0.0 pbpA 3.4.16.4 M penicillin-binding protein
EKFNCIHE_02398 3.4e-228 yqgE EGP Major facilitator superfamily
EKFNCIHE_02399 6.9e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
EKFNCIHE_02400 2.9e-71 yqgC S protein conserved in bacteria
EKFNCIHE_02401 2.4e-128 yqgB S Protein of unknown function (DUF1189)
EKFNCIHE_02402 3.1e-47 yqfZ M LysM domain
EKFNCIHE_02403 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EKFNCIHE_02404 2.3e-52 yqfX S membrane
EKFNCIHE_02405 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
EKFNCIHE_02406 2.9e-72 zur P Belongs to the Fur family
EKFNCIHE_02407 5.9e-155 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
EKFNCIHE_02408 9.3e-37 yqfT S Protein of unknown function (DUF2624)
EKFNCIHE_02409 1.3e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EKFNCIHE_02410 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EKFNCIHE_02411 1.7e-40 yqfQ S YqfQ-like protein
EKFNCIHE_02412 3.2e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EKFNCIHE_02413 1.4e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EKFNCIHE_02414 2.9e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
EKFNCIHE_02415 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
EKFNCIHE_02416 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EKFNCIHE_02417 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EKFNCIHE_02418 1.3e-87 yaiI S Belongs to the UPF0178 family
EKFNCIHE_02419 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EKFNCIHE_02420 4.5e-112 ccpN K CBS domain
EKFNCIHE_02421 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EKFNCIHE_02422 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EKFNCIHE_02423 3.4e-143 recO L Involved in DNA repair and RecF pathway recombination
EKFNCIHE_02424 1.8e-16 S YqzL-like protein
EKFNCIHE_02425 2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EKFNCIHE_02426 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EKFNCIHE_02427 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EKFNCIHE_02428 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EKFNCIHE_02429 0.0 yqfF S membrane-associated HD superfamily hydrolase
EKFNCIHE_02430 6.6e-176 phoH T Phosphate starvation-inducible protein PhoH
EKFNCIHE_02431 5.7e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
EKFNCIHE_02432 9.3e-46 yqfC S sporulation protein YqfC
EKFNCIHE_02433 1.5e-50 yqfB
EKFNCIHE_02434 3.8e-118 yqfA S UPF0365 protein
EKFNCIHE_02435 4.9e-230 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
EKFNCIHE_02436 8e-68 yqeY S Yqey-like protein
EKFNCIHE_02437 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EKFNCIHE_02438 5.6e-156 yqeW P COG1283 Na phosphate symporter
EKFNCIHE_02439 3.5e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
EKFNCIHE_02440 3.9e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EKFNCIHE_02441 6.6e-173 prmA J Methylates ribosomal protein L11
EKFNCIHE_02442 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EKFNCIHE_02443 0.0 dnaK O Heat shock 70 kDa protein
EKFNCIHE_02444 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EKFNCIHE_02445 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EKFNCIHE_02446 1.2e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
EKFNCIHE_02447 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EKFNCIHE_02448 2.5e-53 yqxA S Protein of unknown function (DUF3679)
EKFNCIHE_02449 9.2e-220 spoIIP M stage II sporulation protein P
EKFNCIHE_02450 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EKFNCIHE_02451 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
EKFNCIHE_02452 7.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
EKFNCIHE_02453 0.0 comEC S Competence protein ComEC
EKFNCIHE_02454 8e-105 comEB 3.5.4.12 F ComE operon protein 2
EKFNCIHE_02455 1.1e-102 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EKFNCIHE_02456 3.8e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKFNCIHE_02457 2.1e-137 yqeM Q Methyltransferase
EKFNCIHE_02458 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EKFNCIHE_02459 1.8e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
EKFNCIHE_02460 2.1e-105 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EKFNCIHE_02461 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
EKFNCIHE_02462 2.4e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EKFNCIHE_02463 1.3e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EKFNCIHE_02464 7.6e-94 yqeG S hydrolase of the HAD superfamily
EKFNCIHE_02466 7.2e-138 yqeF E GDSL-like Lipase/Acylhydrolase
EKFNCIHE_02467 2.9e-139 3.5.1.104 G Polysaccharide deacetylase
EKFNCIHE_02468 8e-106 yqeD S SNARE associated Golgi protein
EKFNCIHE_02469 4.5e-209 EGP Major facilitator Superfamily
EKFNCIHE_02470 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFNCIHE_02471 1.1e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
EKFNCIHE_02472 3.6e-91 K Transcriptional regulator PadR-like family
EKFNCIHE_02473 1e-146 ydeE K AraC family transcriptional regulator
EKFNCIHE_02475 9.9e-97 adk 2.7.4.3 F adenylate kinase activity
EKFNCIHE_02476 2.8e-22 yyaR K acetyltransferase
EKFNCIHE_02477 1.1e-219 tetL EGP Major facilitator Superfamily
EKFNCIHE_02478 1.4e-79 yyaR K Acetyltransferase (GNAT) domain
EKFNCIHE_02479 8.9e-92 yrdA S DinB family
EKFNCIHE_02480 4.2e-144 S hydrolase
EKFNCIHE_02481 7.3e-144 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
EKFNCIHE_02482 5.9e-129 glvR K Helix-turn-helix domain, rpiR family
EKFNCIHE_02483 1.5e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
EKFNCIHE_02484 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
EKFNCIHE_02485 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
EKFNCIHE_02486 1.9e-180 romA S Beta-lactamase superfamily domain
EKFNCIHE_02487 1.7e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EKFNCIHE_02488 2e-163 yybE K Transcriptional regulator
EKFNCIHE_02489 1.9e-212 ynfM EGP Major facilitator Superfamily
EKFNCIHE_02490 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
EKFNCIHE_02491 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
EKFNCIHE_02492 7.1e-79 yrhH Q methyltransferase
EKFNCIHE_02494 8e-143 focA P Formate nitrite
EKFNCIHE_02495 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
EKFNCIHE_02496 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
EKFNCIHE_02497 7e-81 yrhD S Protein of unknown function (DUF1641)
EKFNCIHE_02498 5.1e-34 yrhC S YrhC-like protein
EKFNCIHE_02499 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EKFNCIHE_02500 8e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
EKFNCIHE_02501 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EKFNCIHE_02502 2.3e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
EKFNCIHE_02503 4.1e-27 yrzA S Protein of unknown function (DUF2536)
EKFNCIHE_02504 8.1e-70 yrrS S Protein of unknown function (DUF1510)
EKFNCIHE_02505 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
EKFNCIHE_02506 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EKFNCIHE_02507 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
EKFNCIHE_02508 6.1e-246 yegQ O COG0826 Collagenase and related proteases
EKFNCIHE_02509 1.7e-173 yegQ O Peptidase U32
EKFNCIHE_02510 2.3e-116 yrrM 2.1.1.104 S O-methyltransferase
EKFNCIHE_02511 4.1e-190 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EKFNCIHE_02512 7.1e-46 yrzB S Belongs to the UPF0473 family
EKFNCIHE_02513 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EKFNCIHE_02514 8.5e-41 yrzL S Belongs to the UPF0297 family
EKFNCIHE_02515 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EKFNCIHE_02516 2e-162 yrrI S AI-2E family transporter
EKFNCIHE_02517 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EKFNCIHE_02518 1.2e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
EKFNCIHE_02519 6.1e-109 gluC P ABC transporter
EKFNCIHE_02520 2.9e-106 glnP P ABC transporter
EKFNCIHE_02521 2.1e-08 S Protein of unknown function (DUF3918)
EKFNCIHE_02522 2.9e-30 yrzR
EKFNCIHE_02523 3.4e-82 yrrD S protein conserved in bacteria
EKFNCIHE_02524 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EKFNCIHE_02525 1.7e-18 S COG0457 FOG TPR repeat
EKFNCIHE_02526 3.2e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EKFNCIHE_02527 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
EKFNCIHE_02528 7.8e-64 cymR K Transcriptional regulator
EKFNCIHE_02529 8.2e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EKFNCIHE_02530 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EKFNCIHE_02531 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EKFNCIHE_02532 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
EKFNCIHE_02535 8.5e-274 lytH 3.5.1.28 M COG3103 SH3 domain protein
EKFNCIHE_02536 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EKFNCIHE_02537 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EKFNCIHE_02538 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EKFNCIHE_02539 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
EKFNCIHE_02540 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
EKFNCIHE_02541 2.1e-85 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
EKFNCIHE_02542 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKFNCIHE_02543 8.5e-50 yrzD S Post-transcriptional regulator
EKFNCIHE_02544 4.6e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKFNCIHE_02545 9.5e-110 yrbG S membrane
EKFNCIHE_02546 2.4e-60 yrzE S Protein of unknown function (DUF3792)
EKFNCIHE_02547 2.5e-37 yajC U Preprotein translocase subunit YajC
EKFNCIHE_02548 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EKFNCIHE_02549 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EKFNCIHE_02550 2.8e-20 yrzS S Protein of unknown function (DUF2905)
EKFNCIHE_02551 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EKFNCIHE_02552 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EKFNCIHE_02553 3.7e-93 bofC S BofC C-terminal domain
EKFNCIHE_02555 3.2e-48 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EKFNCIHE_02556 2.1e-115 safA M spore coat assembly protein SafA
EKFNCIHE_02557 2.7e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EKFNCIHE_02558 7.6e-152 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
EKFNCIHE_02559 1.1e-294 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
EKFNCIHE_02560 3.6e-221 nifS 2.8.1.7 E Cysteine desulfurase
EKFNCIHE_02561 8.7e-93 niaR S small molecule binding protein (contains 3H domain)
EKFNCIHE_02562 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
EKFNCIHE_02563 1.1e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
EKFNCIHE_02564 3.8e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EKFNCIHE_02565 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
EKFNCIHE_02566 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EKFNCIHE_02567 9.2e-56 ysxB J ribosomal protein
EKFNCIHE_02568 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
EKFNCIHE_02569 3e-159 spoIVFB S Stage IV sporulation protein
EKFNCIHE_02570 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
EKFNCIHE_02571 2.3e-142 minD D Belongs to the ParA family
EKFNCIHE_02572 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EKFNCIHE_02573 5.4e-84 mreD M shape-determining protein
EKFNCIHE_02574 3.6e-157 mreC M Involved in formation and maintenance of cell shape
EKFNCIHE_02575 4e-184 mreB D Rod shape-determining protein MreB
EKFNCIHE_02576 5.3e-127 radC E Belongs to the UPF0758 family
EKFNCIHE_02577 2.1e-97 maf D septum formation protein Maf
EKFNCIHE_02578 2.2e-134 spoIIB S Sporulation related domain
EKFNCIHE_02579 1.1e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EKFNCIHE_02580 3.1e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EKFNCIHE_02581 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EKFNCIHE_02582 2.1e-25
EKFNCIHE_02583 9.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EKFNCIHE_02584 6.4e-225 spoVID M stage VI sporulation protein D
EKFNCIHE_02585 2.8e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
EKFNCIHE_02586 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
EKFNCIHE_02587 3.6e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
EKFNCIHE_02588 3.5e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EKFNCIHE_02589 1e-145 hemX O cytochrome C
EKFNCIHE_02590 7.7e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EKFNCIHE_02591 3.8e-87 ysxD
EKFNCIHE_02592 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
EKFNCIHE_02593 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EKFNCIHE_02594 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
EKFNCIHE_02595 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EKFNCIHE_02596 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EKFNCIHE_02597 3.9e-187 ysoA H Tetratricopeptide repeat
EKFNCIHE_02598 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EKFNCIHE_02599 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EKFNCIHE_02600 1.1e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EKFNCIHE_02601 1.3e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EKFNCIHE_02602 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EKFNCIHE_02603 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
EKFNCIHE_02604 0.0 ilvB 2.2.1.6 E Acetolactate synthase
EKFNCIHE_02609 5.9e-91 ysnB S Phosphoesterase
EKFNCIHE_02610 9.5e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EKFNCIHE_02611 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EKFNCIHE_02612 5.3e-198 gerM S COG5401 Spore germination protein
EKFNCIHE_02613 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EKFNCIHE_02614 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
EKFNCIHE_02615 2e-30 gerE K Transcriptional regulator
EKFNCIHE_02616 2.7e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
EKFNCIHE_02617 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
EKFNCIHE_02618 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
EKFNCIHE_02619 4.8e-108 sdhC C succinate dehydrogenase
EKFNCIHE_02620 2e-79 yslB S Protein of unknown function (DUF2507)
EKFNCIHE_02621 9.2e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
EKFNCIHE_02622 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EKFNCIHE_02623 2.5e-52 trxA O Belongs to the thioredoxin family
EKFNCIHE_02624 6.2e-298 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
EKFNCIHE_02625 6e-177 etfA C Electron transfer flavoprotein
EKFNCIHE_02626 1.7e-137 etfB C Electron transfer flavoprotein
EKFNCIHE_02627 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
EKFNCIHE_02628 2.7e-103 fadR K Transcriptional regulator
EKFNCIHE_02629 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EKFNCIHE_02630 1.6e-115 ywbB S Protein of unknown function (DUF2711)
EKFNCIHE_02631 4.7e-67 yshE S membrane
EKFNCIHE_02632 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EKFNCIHE_02633 0.0 polX L COG1796 DNA polymerase IV (family X)
EKFNCIHE_02634 3.6e-83 cvpA S membrane protein, required for colicin V production
EKFNCIHE_02635 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EKFNCIHE_02636 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EKFNCIHE_02637 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EKFNCIHE_02638 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EKFNCIHE_02639 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKFNCIHE_02640 2e-32 sspI S Belongs to the SspI family
EKFNCIHE_02641 2.7e-202 ysfB KT regulator
EKFNCIHE_02642 1.6e-258 glcD 1.1.3.15 C FAD binding domain
EKFNCIHE_02643 8.9e-256 glcF C Glycolate oxidase
EKFNCIHE_02644 0.0 cstA T Carbon starvation protein
EKFNCIHE_02645 8.6e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
EKFNCIHE_02646 1.2e-144 araQ G transport system permease
EKFNCIHE_02647 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
EKFNCIHE_02648 2.9e-251 araN G carbohydrate transport
EKFNCIHE_02649 8e-224 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EKFNCIHE_02650 7.8e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
EKFNCIHE_02651 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EKFNCIHE_02652 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
EKFNCIHE_02653 4e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
EKFNCIHE_02654 2e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
EKFNCIHE_02655 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
EKFNCIHE_02656 1.9e-65 ysdB S Sigma-w pathway protein YsdB
EKFNCIHE_02657 2.6e-42 ysdA S Membrane
EKFNCIHE_02658 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EKFNCIHE_02659 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EKFNCIHE_02660 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EKFNCIHE_02661 5.4e-108 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EKFNCIHE_02662 2.9e-38 lrgA S effector of murein hydrolase LrgA
EKFNCIHE_02663 2.4e-130 lytT T COG3279 Response regulator of the LytR AlgR family
EKFNCIHE_02664 0.0 lytS 2.7.13.3 T Histidine kinase
EKFNCIHE_02665 5.1e-150 ysaA S HAD-hyrolase-like
EKFNCIHE_02666 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EKFNCIHE_02667 6.7e-153 ytxC S YtxC-like family
EKFNCIHE_02668 4.3e-107 ytxB S SNARE associated Golgi protein
EKFNCIHE_02669 9.5e-172 dnaI L Primosomal protein DnaI
EKFNCIHE_02670 9.1e-251 dnaB L Membrane attachment protein
EKFNCIHE_02671 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EKFNCIHE_02672 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EKFNCIHE_02673 1.1e-194 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EKFNCIHE_02674 2e-67 ytcD K Transcriptional regulator
EKFNCIHE_02675 4.5e-206 ytbD EGP Major facilitator Superfamily
EKFNCIHE_02676 7.6e-160 ytbE S reductase
EKFNCIHE_02677 2.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EKFNCIHE_02678 6.8e-105 ytaF P Probably functions as a manganese efflux pump
EKFNCIHE_02679 4.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EKFNCIHE_02680 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EKFNCIHE_02681 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
EKFNCIHE_02682 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFNCIHE_02683 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
EKFNCIHE_02684 1.2e-241 icd 1.1.1.42 C isocitrate
EKFNCIHE_02685 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
EKFNCIHE_02686 2.1e-46 yjdF S Protein of unknown function (DUF2992)
EKFNCIHE_02687 1.1e-72 yeaL S membrane
EKFNCIHE_02688 6.9e-193 ytvI S sporulation integral membrane protein YtvI
EKFNCIHE_02689 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
EKFNCIHE_02690 7.5e-295 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EKFNCIHE_02691 2e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EKFNCIHE_02692 5.3e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EKFNCIHE_02693 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EKFNCIHE_02694 2.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
EKFNCIHE_02695 0.0 dnaE 2.7.7.7 L DNA polymerase
EKFNCIHE_02696 3.2e-56 ytrH S Sporulation protein YtrH
EKFNCIHE_02697 4.3e-86 ytrI
EKFNCIHE_02698 5.8e-23
EKFNCIHE_02699 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
EKFNCIHE_02700 1.5e-46 ytpI S YtpI-like protein
EKFNCIHE_02701 1.6e-236 ytoI K transcriptional regulator containing CBS domains
EKFNCIHE_02702 1.3e-128 ytkL S Belongs to the UPF0173 family
EKFNCIHE_02703 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFNCIHE_02705 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
EKFNCIHE_02706 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EKFNCIHE_02707 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
EKFNCIHE_02708 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EKFNCIHE_02709 9.3e-178 ytxK 2.1.1.72 L DNA methylase
EKFNCIHE_02710 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EKFNCIHE_02711 1.6e-60 ytfJ S Sporulation protein YtfJ
EKFNCIHE_02712 1e-93 ytfI S Protein of unknown function (DUF2953)
EKFNCIHE_02713 4.5e-88 yteJ S RDD family
EKFNCIHE_02714 6.4e-182 sppA OU signal peptide peptidase SppA
EKFNCIHE_02715 8.3e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EKFNCIHE_02716 0.0 ytcJ S amidohydrolase
EKFNCIHE_02717 4.2e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EKFNCIHE_02718 3.9e-31 sspB S spore protein
EKFNCIHE_02719 4.8e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EKFNCIHE_02720 3.8e-207 iscS2 2.8.1.7 E Cysteine desulfurase
EKFNCIHE_02721 3.2e-237 braB E Component of the transport system for branched-chain amino acids
EKFNCIHE_02722 2.1e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EKFNCIHE_02723 3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EKFNCIHE_02724 3.8e-108 yttP K Transcriptional regulator
EKFNCIHE_02725 1.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
EKFNCIHE_02726 9.5e-282 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
EKFNCIHE_02727 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EKFNCIHE_02728 2.3e-254 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
EKFNCIHE_02729 9.9e-100 yokH G SMI1 / KNR4 family
EKFNCIHE_02730 9.2e-220 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EKFNCIHE_02731 2.5e-09
EKFNCIHE_02732 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
EKFNCIHE_02734 1.5e-135 E GDSL-like Lipase/Acylhydrolase family
EKFNCIHE_02735 8.1e-149 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKFNCIHE_02736 1.4e-147 K Transcriptional regulator
EKFNCIHE_02737 5.2e-125 azlC E AzlC protein
EKFNCIHE_02738 1.6e-46 azlD S Branched-chain amino acid transport protein (AzlD)
EKFNCIHE_02739 4.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EKFNCIHE_02740 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EKFNCIHE_02741 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EKFNCIHE_02742 4.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
EKFNCIHE_02743 1.1e-228 acuC BQ histone deacetylase
EKFNCIHE_02744 3.7e-120 motS N Flagellar motor protein
EKFNCIHE_02745 6.6e-145 motA N flagellar motor
EKFNCIHE_02746 6.4e-182 ccpA K catabolite control protein A
EKFNCIHE_02747 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EKFNCIHE_02748 2.5e-42 ytxJ O Protein of unknown function (DUF2847)
EKFNCIHE_02749 1.7e-16 ytxH S COG4980 Gas vesicle protein
EKFNCIHE_02750 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EKFNCIHE_02751 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EKFNCIHE_02752 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
EKFNCIHE_02753 2.4e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EKFNCIHE_02754 1.4e-147 ytpQ S Belongs to the UPF0354 family
EKFNCIHE_02755 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EKFNCIHE_02756 3.2e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
EKFNCIHE_02757 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EKFNCIHE_02758 1.7e-51 ytzB S small secreted protein
EKFNCIHE_02759 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
EKFNCIHE_02760 2.1e-162 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
EKFNCIHE_02761 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EKFNCIHE_02762 3.5e-45 ytzH S YtzH-like protein
EKFNCIHE_02763 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
EKFNCIHE_02764 4e-147 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
EKFNCIHE_02765 1.2e-166 ytlQ
EKFNCIHE_02766 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EKFNCIHE_02767 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EKFNCIHE_02768 3.1e-267 pepV 3.5.1.18 E Dipeptidase
EKFNCIHE_02769 1.3e-227 pbuO S permease
EKFNCIHE_02770 4.6e-216 ythQ U Bacterial ABC transporter protein EcsB
EKFNCIHE_02771 6.4e-128 ythP V ABC transporter
EKFNCIHE_02772 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
EKFNCIHE_02773 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EKFNCIHE_02774 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKFNCIHE_02775 5.7e-236 ytfP S HI0933-like protein
EKFNCIHE_02776 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
EKFNCIHE_02777 9e-26 yteV S Sporulation protein Cse60
EKFNCIHE_02778 6.3e-185 msmR K Transcriptional regulator
EKFNCIHE_02779 7.5e-244 msmE G Bacterial extracellular solute-binding protein
EKFNCIHE_02780 1.6e-168 amyD G Binding-protein-dependent transport system inner membrane component
EKFNCIHE_02781 5.3e-142 amyC P ABC transporter (permease)
EKFNCIHE_02782 1e-248 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
EKFNCIHE_02783 1.7e-84 M Acetyltransferase (GNAT) domain
EKFNCIHE_02784 5.6e-52 ytwF P Sulfurtransferase
EKFNCIHE_02785 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EKFNCIHE_02786 1.2e-52 ytvB S Protein of unknown function (DUF4257)
EKFNCIHE_02787 3.8e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EKFNCIHE_02788 1.8e-207 yttB EGP Major facilitator Superfamily
EKFNCIHE_02789 1.4e-122 ywaF S Integral membrane protein
EKFNCIHE_02790 0.0 bceB V ABC transporter (permease)
EKFNCIHE_02791 4.9e-134 bceA V ABC transporter, ATP-binding protein
EKFNCIHE_02792 3.3e-178 T PhoQ Sensor
EKFNCIHE_02793 1.4e-89 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFNCIHE_02794 1.4e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
EKFNCIHE_02795 2.2e-125 ytrE V ABC transporter, ATP-binding protein
EKFNCIHE_02796 4e-152
EKFNCIHE_02797 6.5e-171 P ABC-2 family transporter protein
EKFNCIHE_02798 1.3e-163 S ABC-2 family transporter protein
EKFNCIHE_02799 1.9e-161 ytrB P abc transporter atp-binding protein
EKFNCIHE_02800 3.9e-66 ytrA K GntR family transcriptional regulator
EKFNCIHE_02802 7.4e-40 ytzC S Protein of unknown function (DUF2524)
EKFNCIHE_02803 6.8e-193 K helix_turn_helix, Arsenical Resistance Operon Repressor
EKFNCIHE_02804 2e-281 norB EGP COG0477 Permeases of the major facilitator superfamily
EKFNCIHE_02805 1.1e-189 yhcC S Fe-S oxidoreductase
EKFNCIHE_02806 2.8e-105 ytqB J Putative rRNA methylase
EKFNCIHE_02808 1.5e-141 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
EKFNCIHE_02809 1.6e-210 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
EKFNCIHE_02810 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
EKFNCIHE_02811 3.9e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EKFNCIHE_02812 6.3e-260 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
EKFNCIHE_02813 0.0 asnB 6.3.5.4 E Asparagine synthase
EKFNCIHE_02814 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EKFNCIHE_02815 1.2e-307 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EKFNCIHE_02816 1.6e-38 ytmB S Protein of unknown function (DUF2584)
EKFNCIHE_02817 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EKFNCIHE_02818 8.9e-184 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EKFNCIHE_02819 3.2e-144 ytlC P ABC transporter
EKFNCIHE_02820 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EKFNCIHE_02821 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
EKFNCIHE_02822 5e-61 ytkC S Bacteriophage holin family
EKFNCIHE_02823 7.8e-76 dps P Belongs to the Dps family
EKFNCIHE_02825 5.7e-74 ytkA S YtkA-like
EKFNCIHE_02826 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EKFNCIHE_02827 1.2e-38 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EKFNCIHE_02828 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
EKFNCIHE_02829 7.9e-41 rpmE2 J Ribosomal protein L31
EKFNCIHE_02830 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
EKFNCIHE_02831 2.4e-184 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EKFNCIHE_02832 2e-23 S Domain of Unknown Function (DUF1540)
EKFNCIHE_02833 1.6e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EKFNCIHE_02834 2e-277 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EKFNCIHE_02835 4.6e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EKFNCIHE_02836 2.1e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EKFNCIHE_02837 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EKFNCIHE_02838 1.2e-271 menF 5.4.4.2 HQ Isochorismate synthase
EKFNCIHE_02839 2.4e-130 dksA T COG1734 DnaK suppressor protein
EKFNCIHE_02840 1.3e-76 tspO T membrane
EKFNCIHE_02849 7.8e-08
EKFNCIHE_02850 1.3e-09
EKFNCIHE_02857 1.6e-08
EKFNCIHE_02862 3.4e-39 S COG NOG14552 non supervised orthologous group
EKFNCIHE_02863 8.2e-97 thiT S Thiamine transporter protein (Thia_YuaJ)
EKFNCIHE_02864 5e-178 yuaG 3.4.21.72 S protein conserved in bacteria
EKFNCIHE_02865 7.3e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
EKFNCIHE_02866 6.9e-73 yuaE S DinB superfamily
EKFNCIHE_02867 2.5e-109 yuaD S MOSC domain
EKFNCIHE_02868 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
EKFNCIHE_02869 3.2e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
EKFNCIHE_02870 8.6e-96 yuaC K Belongs to the GbsR family
EKFNCIHE_02871 7.9e-94 yuaB
EKFNCIHE_02872 1.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
EKFNCIHE_02873 9e-145 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EKFNCIHE_02874 3.2e-217 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EKFNCIHE_02875 3.5e-117 G Cupin
EKFNCIHE_02876 3.4e-52 yjcN
EKFNCIHE_02878 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EKFNCIHE_02879 2.2e-194 yubA S transporter activity
EKFNCIHE_02880 2.1e-185 ygjR S Oxidoreductase
EKFNCIHE_02881 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
EKFNCIHE_02882 2.6e-235 mcpA NT chemotaxis protein
EKFNCIHE_02883 6e-224 mcpA NT chemotaxis protein
EKFNCIHE_02884 5.8e-235 mcpA NT chemotaxis protein
EKFNCIHE_02885 8.1e-221 mcpA NT chemotaxis protein
EKFNCIHE_02886 4.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
EKFNCIHE_02887 1.4e-40
EKFNCIHE_02888 2.3e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EKFNCIHE_02889 2.7e-73 yugU S Uncharacterised protein family UPF0047
EKFNCIHE_02890 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
EKFNCIHE_02891 2.5e-231 yugS S COG1253 Hemolysins and related proteins containing CBS domains
EKFNCIHE_02892 8.3e-117 yugP S Zn-dependent protease
EKFNCIHE_02893 3.4e-18
EKFNCIHE_02894 6.7e-27 mstX S Membrane-integrating protein Mistic
EKFNCIHE_02895 1.8e-181 yugO P COG1226 Kef-type K transport systems
EKFNCIHE_02896 7e-71 yugN S YugN-like family
EKFNCIHE_02898 1.5e-258 pgi 5.3.1.9 G Belongs to the GPI family
EKFNCIHE_02899 4.1e-93 S NADPH-dependent FMN reductase
EKFNCIHE_02900 5.5e-118 ycaC Q Isochorismatase family
EKFNCIHE_02901 1.4e-228 yugK C Dehydrogenase
EKFNCIHE_02902 1.6e-224 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
EKFNCIHE_02903 1.8e-34 yuzA S Domain of unknown function (DUF378)
EKFNCIHE_02904 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
EKFNCIHE_02905 1.6e-208 yugH 2.6.1.1 E Aminotransferase
EKFNCIHE_02906 2e-83 alaR K Transcriptional regulator
EKFNCIHE_02907 5.5e-155 yugF I Hydrolase
EKFNCIHE_02908 1.4e-40 yugE S Domain of unknown function (DUF1871)
EKFNCIHE_02909 1.3e-223 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EKFNCIHE_02910 8.9e-229 T PhoQ Sensor
EKFNCIHE_02911 7.7e-67 kapB G Kinase associated protein B
EKFNCIHE_02912 4e-118 kapD L the KinA pathway to sporulation
EKFNCIHE_02913 4.5e-185 yuxJ EGP Major facilitator Superfamily
EKFNCIHE_02914 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
EKFNCIHE_02915 2.2e-72 yuxK S protein conserved in bacteria
EKFNCIHE_02916 9.3e-74 yufK S Family of unknown function (DUF5366)
EKFNCIHE_02917 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EKFNCIHE_02918 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
EKFNCIHE_02919 1.7e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
EKFNCIHE_02920 1e-284 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
EKFNCIHE_02921 8.4e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
EKFNCIHE_02922 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
EKFNCIHE_02923 2.3e-12
EKFNCIHE_02924 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EKFNCIHE_02925 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKFNCIHE_02926 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKFNCIHE_02927 1.7e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKFNCIHE_02928 8.5e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKFNCIHE_02929 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKFNCIHE_02930 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
EKFNCIHE_02931 1.1e-62 ydiI Q protein, possibly involved in aromatic compounds catabolism
EKFNCIHE_02932 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFNCIHE_02933 1.2e-276 comP 2.7.13.3 T Histidine kinase
EKFNCIHE_02935 8.9e-98 comQ H Belongs to the FPP GGPP synthase family
EKFNCIHE_02938 1.2e-50 yuzC
EKFNCIHE_02939 3.8e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
EKFNCIHE_02940 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EKFNCIHE_02941 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
EKFNCIHE_02942 7.2e-68 yueI S Protein of unknown function (DUF1694)
EKFNCIHE_02943 2.8e-38 yueH S YueH-like protein
EKFNCIHE_02944 6.4e-34 yueG S Spore germination protein gerPA/gerPF
EKFNCIHE_02945 3.6e-186 yueF S transporter activity
EKFNCIHE_02946 1.6e-22 S Protein of unknown function (DUF2642)
EKFNCIHE_02947 8.3e-96 yueE S phosphohydrolase
EKFNCIHE_02948 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFNCIHE_02949 6.5e-76 yueC S Family of unknown function (DUF5383)
EKFNCIHE_02950 0.0 esaA S type VII secretion protein EsaA
EKFNCIHE_02951 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EKFNCIHE_02952 1.2e-204 essB S WXG100 protein secretion system (Wss), protein YukC
EKFNCIHE_02953 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
EKFNCIHE_02954 3.3e-46 esxA S Belongs to the WXG100 family
EKFNCIHE_02955 4.2e-228 yukF QT Transcriptional regulator
EKFNCIHE_02956 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
EKFNCIHE_02957 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
EKFNCIHE_02958 1.1e-33 mbtH S MbtH-like protein
EKFNCIHE_02959 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFNCIHE_02960 3.6e-171 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
EKFNCIHE_02961 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
EKFNCIHE_02962 8.6e-218 entC 5.4.4.2 HQ Isochorismate synthase
EKFNCIHE_02963 5.3e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFNCIHE_02964 1.2e-163 besA S Putative esterase
EKFNCIHE_02965 3.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
EKFNCIHE_02966 1.1e-101 bioY S Biotin biosynthesis protein
EKFNCIHE_02967 3.1e-208 yuiF S antiporter
EKFNCIHE_02968 6.8e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EKFNCIHE_02969 1.6e-77 yuiD S protein conserved in bacteria
EKFNCIHE_02970 2.7e-117 yuiC S protein conserved in bacteria
EKFNCIHE_02971 9.9e-28 yuiB S Putative membrane protein
EKFNCIHE_02972 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
EKFNCIHE_02973 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
EKFNCIHE_02975 5.7e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EKFNCIHE_02976 4.8e-29
EKFNCIHE_02977 2.6e-70 CP Membrane
EKFNCIHE_02978 1.5e-121 V ABC transporter
EKFNCIHE_02980 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
EKFNCIHE_02982 1e-26 K helix_turn_helix, mercury resistance
EKFNCIHE_02983 8.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFNCIHE_02984 1.1e-62 erpA S Belongs to the HesB IscA family
EKFNCIHE_02985 1.4e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EKFNCIHE_02986 5e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKFNCIHE_02987 2.4e-39 yuzB S Belongs to the UPF0349 family
EKFNCIHE_02988 5.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
EKFNCIHE_02989 1.1e-53 yuzD S protein conserved in bacteria
EKFNCIHE_02990 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
EKFNCIHE_02991 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
EKFNCIHE_02992 9.8e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EKFNCIHE_02993 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EKFNCIHE_02994 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
EKFNCIHE_02995 3e-195 yutH S Spore coat protein
EKFNCIHE_02996 3.3e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
EKFNCIHE_02997 3.6e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EKFNCIHE_02998 6.8e-72 yutE S Protein of unknown function DUF86
EKFNCIHE_02999 1.7e-47 yutD S protein conserved in bacteria
EKFNCIHE_03000 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EKFNCIHE_03001 6.6e-192 lytH M Peptidase, M23
EKFNCIHE_03002 3.3e-130 yunB S Sporulation protein YunB (Spo_YunB)
EKFNCIHE_03003 2.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
EKFNCIHE_03004 1.1e-144 yunE S membrane transporter protein
EKFNCIHE_03005 1.5e-168 yunF S Protein of unknown function DUF72
EKFNCIHE_03006 2.4e-59 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
EKFNCIHE_03007 1.2e-260 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EKFNCIHE_03008 3.4e-302 pucR QT COG2508 Regulator of polyketide synthase expression
EKFNCIHE_03009 1.5e-21
EKFNCIHE_03011 4.1e-212 blt EGP Major facilitator Superfamily
EKFNCIHE_03012 6.2e-235 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EKFNCIHE_03013 4.4e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EKFNCIHE_03014 1.6e-165 bsn L Ribonuclease
EKFNCIHE_03015 2.7e-205 msmX P Belongs to the ABC transporter superfamily
EKFNCIHE_03016 3.6e-134 yurK K UTRA
EKFNCIHE_03017 1.5e-160 yurL 2.7.1.218 G pfkB family carbohydrate kinase
EKFNCIHE_03018 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
EKFNCIHE_03019 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
EKFNCIHE_03020 5.2e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
EKFNCIHE_03021 2.7e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EKFNCIHE_03022 1.9e-164 K helix_turn_helix, mercury resistance
EKFNCIHE_03024 7e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
EKFNCIHE_03025 3.1e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
EKFNCIHE_03026 4.1e-127 Q ubiE/COQ5 methyltransferase family
EKFNCIHE_03027 2.9e-63 yncE S Protein of unknown function (DUF2691)
EKFNCIHE_03028 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EKFNCIHE_03029 8.4e-09
EKFNCIHE_03032 1.1e-68 3.5.1.28 M Ami_2
EKFNCIHE_03033 6.9e-61 S Pfam:Phage_holin_4_1
EKFNCIHE_03034 1.7e-09 S Phage uncharacterised protein (Phage_XkdX)
EKFNCIHE_03036 3.5e-137 S Domain of unknown function (DUF2479)
EKFNCIHE_03037 4.2e-286 M Pectate lyase superfamily protein
EKFNCIHE_03038 5.9e-104 mur1 NU Prophage endopeptidase tail
EKFNCIHE_03039 1e-39 S Phage tail protein
EKFNCIHE_03040 1.4e-140 D Phage-related minor tail protein
EKFNCIHE_03042 6.8e-52 S phage major tail protein, phi13 family
EKFNCIHE_03043 1.5e-17
EKFNCIHE_03044 9.5e-14 S TIGRFAM phage protein, HK97 gp10 family
EKFNCIHE_03045 2.2e-09 S Phage head-tail adaptor
EKFNCIHE_03046 5e-12 S Phage gp6-like head-tail connector protein
EKFNCIHE_03047 2.5e-90 S Phage capsid family
EKFNCIHE_03048 5.4e-48 S Caudovirus prohead serine protease
EKFNCIHE_03049 1.5e-110 S Phage portal protein
EKFNCIHE_03050 3.6e-148 S Phage Terminase
EKFNCIHE_03051 1.5e-17
EKFNCIHE_03052 5.1e-28 L HNH endonuclease
EKFNCIHE_03055 9e-09 ftsK D Ftsk_gamma
EKFNCIHE_03057 3e-77 L Phage integrase family
EKFNCIHE_03058 1.8e-52 wecC 1.1.1.336 M ArpU family transcriptional regulator
EKFNCIHE_03060 5.9e-10
EKFNCIHE_03061 1.2e-87
EKFNCIHE_03063 6.3e-27
EKFNCIHE_03065 3.6e-15 yqaO S Phage-like element PBSX protein XtrA
EKFNCIHE_03068 9e-29
EKFNCIHE_03071 1.7e-42 dnaC L IstB-like ATP binding protein
EKFNCIHE_03072 3.8e-69 L dnaD_dom DnaD domain protein
EKFNCIHE_03074 1.5e-14
EKFNCIHE_03075 4.6e-43 K Helix-turn-helix XRE-family like proteins
EKFNCIHE_03077 8.8e-47
EKFNCIHE_03078 1.4e-115 int L Belongs to the 'phage' integrase family
EKFNCIHE_03079 8.7e-270 sufB O FeS cluster assembly
EKFNCIHE_03080 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
EKFNCIHE_03081 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EKFNCIHE_03082 1.2e-244 sufD O assembly protein SufD
EKFNCIHE_03083 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EKFNCIHE_03084 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKFNCIHE_03085 3e-145 metQ P Belongs to the NlpA lipoprotein family
EKFNCIHE_03086 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
EKFNCIHE_03087 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EKFNCIHE_03088 1.5e-56 yusD S SCP-2 sterol transfer family
EKFNCIHE_03089 1.6e-54 yusE CO Thioredoxin
EKFNCIHE_03090 4.9e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
EKFNCIHE_03091 3.7e-40 yusG S Protein of unknown function (DUF2553)
EKFNCIHE_03092 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EKFNCIHE_03093 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
EKFNCIHE_03094 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
EKFNCIHE_03095 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
EKFNCIHE_03096 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
EKFNCIHE_03097 4.9e-165 fadM E Proline dehydrogenase
EKFNCIHE_03098 8.9e-210 yusP P Major facilitator superfamily
EKFNCIHE_03099 1.1e-42
EKFNCIHE_03100 1.1e-53 yusN M Coat F domain
EKFNCIHE_03101 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
EKFNCIHE_03102 1.4e-287 yusP P Major facilitator superfamily
EKFNCIHE_03103 8.5e-154 ywbI2 K Transcriptional regulator
EKFNCIHE_03104 4.2e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
EKFNCIHE_03105 7.1e-184 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EKFNCIHE_03106 3.3e-39 yusU S Protein of unknown function (DUF2573)
EKFNCIHE_03107 3.1e-150 yusV 3.6.3.34 HP ABC transporter
EKFNCIHE_03108 7.2e-45 S YusW-like protein
EKFNCIHE_03109 0.0 pepF2 E COG1164 Oligoendopeptidase F
EKFNCIHE_03110 2.7e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFNCIHE_03111 4.7e-79 dps P Belongs to the Dps family
EKFNCIHE_03112 5e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKFNCIHE_03113 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFNCIHE_03114 2.2e-249 cssS 2.7.13.3 T PhoQ Sensor
EKFNCIHE_03115 3.4e-24
EKFNCIHE_03116 6.5e-157 yuxN K Transcriptional regulator
EKFNCIHE_03117 8.7e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EKFNCIHE_03118 6.6e-24 S Protein of unknown function (DUF3970)
EKFNCIHE_03119 3.5e-258 gerAA EG Spore germination protein
EKFNCIHE_03120 3.6e-186 gerAB E Spore germination protein
EKFNCIHE_03121 6e-205 gerAC S Spore germination B3/ GerAC like, C-terminal
EKFNCIHE_03122 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFNCIHE_03123 2.3e-193 vraS 2.7.13.3 T Histidine kinase
EKFNCIHE_03124 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
EKFNCIHE_03125 7.4e-126 liaG S Putative adhesin
EKFNCIHE_03126 1.5e-89 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EKFNCIHE_03127 5.3e-44 liaI S membrane
EKFNCIHE_03128 1.8e-226 yvqJ EGP Major facilitator Superfamily
EKFNCIHE_03129 2.7e-100 yvqK 2.5.1.17 S Adenosyltransferase
EKFNCIHE_03130 1.4e-218 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EKFNCIHE_03131 6e-178 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFNCIHE_03132 1e-165 yvrC P ABC transporter substrate-binding protein
EKFNCIHE_03133 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFNCIHE_03134 1.1e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
EKFNCIHE_03135 0.0 T PhoQ Sensor
EKFNCIHE_03136 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFNCIHE_03137 1.1e-36
EKFNCIHE_03138 3.8e-102 yvrI K RNA polymerase
EKFNCIHE_03139 6.1e-15 S YvrJ protein family
EKFNCIHE_03140 7.8e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
EKFNCIHE_03141 9.3e-66 yvrL S Regulatory protein YrvL
EKFNCIHE_03142 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
EKFNCIHE_03143 7.6e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFNCIHE_03144 1.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFNCIHE_03145 2.6e-177 fhuD P ABC transporter
EKFNCIHE_03146 1.6e-126 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EKFNCIHE_03147 2.9e-236 yvsH E Arginine ornithine antiporter
EKFNCIHE_03148 5.2e-13 S Small spore protein J (Spore_SspJ)
EKFNCIHE_03149 5.1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
EKFNCIHE_03150 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EKFNCIHE_03151 2.3e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
EKFNCIHE_03152 2.6e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
EKFNCIHE_03153 7.9e-99 modB P COG4149 ABC-type molybdate transport system, permease component
EKFNCIHE_03154 8.6e-114 yfiK K Regulator
EKFNCIHE_03155 4.3e-179 T Histidine kinase
EKFNCIHE_03156 1.8e-170 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
EKFNCIHE_03157 1.3e-191 yfiM V ABC-2 type transporter
EKFNCIHE_03158 7e-193 yfiN V COG0842 ABC-type multidrug transport system, permease component
EKFNCIHE_03159 5e-156 yvgN S reductase
EKFNCIHE_03160 2.7e-85 yvgO
EKFNCIHE_03161 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
EKFNCIHE_03162 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EKFNCIHE_03163 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EKFNCIHE_03164 0.0 helD 3.6.4.12 L DNA helicase
EKFNCIHE_03165 2.3e-105 yvgT S membrane
EKFNCIHE_03166 1.1e-139 S Metallo-peptidase family M12
EKFNCIHE_03167 6e-73 bdbC O Required for disulfide bond formation in some proteins
EKFNCIHE_03168 2.4e-100 bdbD O Thioredoxin
EKFNCIHE_03169 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
EKFNCIHE_03170 0.0 copA 3.6.3.54 P P-type ATPase
EKFNCIHE_03171 2.6e-29 copZ P Heavy-metal-associated domain
EKFNCIHE_03172 3.7e-48 csoR S transcriptional
EKFNCIHE_03173 4.6e-191 yvaA 1.1.1.371 S Oxidoreductase
EKFNCIHE_03174 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EKFNCIHE_03175 8.4e-159 K Helix-turn-helix XRE-family like proteins
EKFNCIHE_03176 2.2e-216 ynfM EGP Major Facilitator Superfamily
EKFNCIHE_03177 2.4e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
EKFNCIHE_03178 1.5e-141 S Amidohydrolase
EKFNCIHE_03179 8.3e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFNCIHE_03180 5.6e-46 ytnI O COG0695 Glutaredoxin and related proteins
EKFNCIHE_03181 3.2e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFNCIHE_03182 1e-139 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EKFNCIHE_03183 8.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
EKFNCIHE_03184 5e-120 tcyL P Binding-protein-dependent transport system inner membrane component
EKFNCIHE_03185 2.7e-146 tcyK M Bacterial periplasmic substrate-binding proteins
EKFNCIHE_03186 3.9e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
EKFNCIHE_03187 3e-101 ytmI K Acetyltransferase (GNAT) domain
EKFNCIHE_03188 3.8e-162 ytlI K LysR substrate binding domain
EKFNCIHE_03189 3.4e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFNCIHE_03190 3.7e-48 yrdF K ribonuclease inhibitor
EKFNCIHE_03191 8.4e-09
EKFNCIHE_03192 2.8e-26
EKFNCIHE_03194 8.2e-72 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EKFNCIHE_03195 4.2e-66 S Pfam:Phage_holin_4_1
EKFNCIHE_03198 6.7e-152 S Domain of unknown function (DUF2479)
EKFNCIHE_03199 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
EKFNCIHE_03200 2.2e-227 NU Prophage endopeptidase tail
EKFNCIHE_03201 1.6e-109 S Phage tail protein
EKFNCIHE_03202 0.0 S peptidoglycan catabolic process
EKFNCIHE_03203 1.5e-11
EKFNCIHE_03204 2e-23
EKFNCIHE_03205 4.9e-60
EKFNCIHE_03206 4.3e-30
EKFNCIHE_03207 6.7e-47 S Bacteriophage HK97-gp10, putative tail-component
EKFNCIHE_03208 4.7e-15 S Phage head-tail joining protein
EKFNCIHE_03209 3.2e-24 S Phage gp6-like head-tail connector protein
EKFNCIHE_03210 3e-37 S peptidoglycan catabolic process
EKFNCIHE_03212 2.7e-179 S capsid protein
EKFNCIHE_03213 9.7e-112 S peptidase activity
EKFNCIHE_03214 2.7e-238 S Phage portal protein
EKFNCIHE_03215 1.8e-10
EKFNCIHE_03216 7e-229 S Phage Terminase
EKFNCIHE_03217 1.1e-84 S Phage terminase, small subunit
EKFNCIHE_03219 1.1e-67 S HNH endonuclease
EKFNCIHE_03222 3e-77 L Phage integrase family
EKFNCIHE_03223 2.5e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
EKFNCIHE_03225 3.4e-47
EKFNCIHE_03231 1.5e-81 S dUTPase
EKFNCIHE_03233 1.3e-102 ydiP 2.1.1.37 H C-5 cytosine-specific DNA methylase
EKFNCIHE_03235 1.6e-27
EKFNCIHE_03237 2.1e-15 yqaO S Phage-like element PBSX protein XtrA
EKFNCIHE_03241 1.2e-28
EKFNCIHE_03242 3.7e-07
EKFNCIHE_03244 6.3e-42 dnaC L IstB-like ATP binding protein
EKFNCIHE_03245 2.4e-76 L dnaD_dom DnaD domain protein
EKFNCIHE_03247 4.8e-38 S Domain of unknown function (DUF771)
EKFNCIHE_03248 3.5e-12 S sequence-specific DNA binding
EKFNCIHE_03250 6.6e-21 K Helix-turn-helix XRE-family like proteins
EKFNCIHE_03252 2.6e-59
EKFNCIHE_03253 5.1e-129 S Phage integrase family
EKFNCIHE_03255 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EKFNCIHE_03256 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EKFNCIHE_03257 6.2e-142 est 3.1.1.1 S Carboxylesterase
EKFNCIHE_03258 4.8e-24 secG U Preprotein translocase subunit SecG
EKFNCIHE_03259 6e-35 yvzC K Transcriptional
EKFNCIHE_03260 1e-69 K transcriptional
EKFNCIHE_03261 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
EKFNCIHE_03262 8.8e-53 yodB K transcriptional
EKFNCIHE_03263 5.3e-259 T His Kinase A (phosphoacceptor) domain
EKFNCIHE_03264 1.4e-121 K Transcriptional regulatory protein, C terminal
EKFNCIHE_03265 7.7e-135 mutG S ABC-2 family transporter protein
EKFNCIHE_03266 4.9e-123 spaE S ABC-2 family transporter protein
EKFNCIHE_03267 1.2e-126 mutF V ABC transporter, ATP-binding protein
EKFNCIHE_03268 3.6e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
EKFNCIHE_03269 1e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EKFNCIHE_03270 1e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
EKFNCIHE_03271 3.3e-206 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EKFNCIHE_03272 4.3e-76 yvbF K Belongs to the GbsR family
EKFNCIHE_03273 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
EKFNCIHE_03274 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EKFNCIHE_03275 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
EKFNCIHE_03276 3.3e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EKFNCIHE_03277 3.5e-97 yvbF K Belongs to the GbsR family
EKFNCIHE_03278 9.8e-104 yvbG U UPF0056 membrane protein
EKFNCIHE_03279 1.1e-119 exoY M Membrane
EKFNCIHE_03280 0.0 tcaA S response to antibiotic
EKFNCIHE_03281 2.5e-80 yvbK 3.1.3.25 K acetyltransferase
EKFNCIHE_03282 1.8e-210 EGP Major facilitator Superfamily
EKFNCIHE_03283 5.7e-177
EKFNCIHE_03284 7e-124 S GlcNAc-PI de-N-acetylase
EKFNCIHE_03285 2.1e-142 C WbqC-like protein family
EKFNCIHE_03286 1.1e-145 M Protein involved in cellulose biosynthesis
EKFNCIHE_03287 2.4e-226 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EKFNCIHE_03288 6.8e-170 5.1.3.2 M GDP-mannose 4,6 dehydratase
EKFNCIHE_03289 4.5e-216 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
EKFNCIHE_03290 8.9e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKFNCIHE_03291 2.2e-235 ywaD 3.4.11.10, 3.4.11.6 S PA domain
EKFNCIHE_03292 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EKFNCIHE_03293 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
EKFNCIHE_03294 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EKFNCIHE_03295 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EKFNCIHE_03296 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EKFNCIHE_03297 2.6e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EKFNCIHE_03299 7.4e-253 araE EGP Major facilitator Superfamily
EKFNCIHE_03300 3.2e-203 araR K transcriptional
EKFNCIHE_03301 2.4e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFNCIHE_03303 5.3e-156 yvbU K Transcriptional regulator
EKFNCIHE_03304 7.7e-158 yvbV EG EamA-like transporter family
EKFNCIHE_03305 1.1e-213 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
EKFNCIHE_03307 5e-151 ybbH_1 K RpiR family transcriptional regulator
EKFNCIHE_03308 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
EKFNCIHE_03309 9.6e-210 gntP EG COG2610 H gluconate symporter and related permeases
EKFNCIHE_03310 7.4e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EKFNCIHE_03311 8e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EKFNCIHE_03312 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EKFNCIHE_03313 1.1e-217 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKFNCIHE_03314 6.6e-120 yvfI K COG2186 Transcriptional regulators
EKFNCIHE_03315 3.8e-304 yvfH C L-lactate permease
EKFNCIHE_03316 7.2e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EKFNCIHE_03317 2.7e-32 yvfG S YvfG protein
EKFNCIHE_03318 3.2e-186 yvfF GM Exopolysaccharide biosynthesis protein
EKFNCIHE_03319 4.1e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
EKFNCIHE_03320 4.2e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
EKFNCIHE_03321 6.3e-108 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EKFNCIHE_03322 1.6e-272 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKFNCIHE_03323 6.8e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
EKFNCIHE_03324 2.9e-204 epsI GM pyruvyl transferase
EKFNCIHE_03325 1.1e-192 epsH GT2 S Glycosyltransferase like family 2
EKFNCIHE_03326 7.7e-205 epsG S EpsG family
EKFNCIHE_03327 2.3e-212 epsF GT4 M Glycosyl transferases group 1
EKFNCIHE_03328 5.8e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EKFNCIHE_03329 1.1e-217 epsD GT4 M Glycosyl transferase 4-like
EKFNCIHE_03330 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
EKFNCIHE_03331 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
EKFNCIHE_03332 1.6e-118 ywqC M biosynthesis protein
EKFNCIHE_03333 1.9e-77 slr K transcriptional
EKFNCIHE_03334 2.7e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
EKFNCIHE_03336 3.7e-96 ywjB H RibD C-terminal domain
EKFNCIHE_03337 1.5e-112 yyaS S Membrane
EKFNCIHE_03338 3e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKFNCIHE_03339 1.6e-93 padC Q Phenolic acid decarboxylase
EKFNCIHE_03340 4.3e-11 S Protein of unknown function (DUF1433)
EKFNCIHE_03341 2.2e-17 S Protein of unknown function (DUF1433)
EKFNCIHE_03342 9.8e-18 S Protein of unknown function (DUF1433)
EKFNCIHE_03343 4.9e-268 I Pfam Lipase (class 3)
EKFNCIHE_03344 2.6e-33
EKFNCIHE_03346 1.4e-291 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
EKFNCIHE_03347 1.5e-217 rafB P LacY proton/sugar symporter
EKFNCIHE_03348 3.3e-183 scrR K transcriptional
EKFNCIHE_03349 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EKFNCIHE_03350 3.3e-163 yraN K Transcriptional regulator
EKFNCIHE_03351 1.4e-209 yraM S PrpF protein
EKFNCIHE_03352 4.6e-247 EGP Sugar (and other) transporter
EKFNCIHE_03353 2.6e-10 yvdD 3.2.2.10 S Belongs to the LOG family
EKFNCIHE_03354 3.6e-105 yvdD 3.2.2.10 S Belongs to the LOG family
EKFNCIHE_03355 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
EKFNCIHE_03356 9.5e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
EKFNCIHE_03357 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
EKFNCIHE_03358 2.3e-181 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKFNCIHE_03359 8.2e-79 M Ribonuclease
EKFNCIHE_03360 5.7e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
EKFNCIHE_03361 4.7e-36 crh G Phosphocarrier protein Chr
EKFNCIHE_03362 5.3e-170 whiA K May be required for sporulation
EKFNCIHE_03363 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EKFNCIHE_03364 1.1e-166 rapZ S Displays ATPase and GTPase activities
EKFNCIHE_03365 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EKFNCIHE_03366 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EKFNCIHE_03367 1.3e-124 usp CBM50 M protein conserved in bacteria
EKFNCIHE_03368 1.1e-275 S COG0457 FOG TPR repeat
EKFNCIHE_03369 2.3e-190 sasA T Histidine kinase
EKFNCIHE_03370 9.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFNCIHE_03371 2.7e-53
EKFNCIHE_03372 0.0 msbA2 3.6.3.44 V ABC transporter
EKFNCIHE_03373 1.8e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
EKFNCIHE_03374 4.9e-134 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EKFNCIHE_03375 6e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EKFNCIHE_03376 3.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EKFNCIHE_03377 2.6e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
EKFNCIHE_03378 3e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EKFNCIHE_03379 1.1e-113 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EKFNCIHE_03380 2.6e-206 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EKFNCIHE_03381 3.5e-137 yvpB NU protein conserved in bacteria
EKFNCIHE_03382 1.3e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
EKFNCIHE_03383 7e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EKFNCIHE_03384 7.6e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EKFNCIHE_03385 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EKFNCIHE_03386 1.7e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EKFNCIHE_03387 1.8e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EKFNCIHE_03388 2.3e-133 yvoA K transcriptional
EKFNCIHE_03389 4.4e-103 yxaF K Transcriptional regulator
EKFNCIHE_03390 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
EKFNCIHE_03391 3.3e-40 yvlD S Membrane
EKFNCIHE_03392 9.6e-26 pspB KT PspC domain
EKFNCIHE_03393 1.2e-165 yvlB S Putative adhesin
EKFNCIHE_03394 6.1e-49 yvlA
EKFNCIHE_03395 2.2e-32 yvkN
EKFNCIHE_03396 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EKFNCIHE_03397 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EKFNCIHE_03398 7.6e-33 csbA S protein conserved in bacteria
EKFNCIHE_03399 0.0 yvkC 2.7.9.2 GT Phosphotransferase
EKFNCIHE_03400 2e-109 yvkB K Transcriptional regulator
EKFNCIHE_03401 9.6e-226 yvkA EGP Major facilitator Superfamily
EKFNCIHE_03402 6.6e-177 S Psort location CytoplasmicMembrane, score
EKFNCIHE_03403 8.3e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKFNCIHE_03404 1.5e-55 swrA S Swarming motility protein
EKFNCIHE_03405 1.1e-251 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
EKFNCIHE_03406 1e-225 ywoF P Right handed beta helix region
EKFNCIHE_03407 2.2e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EKFNCIHE_03408 2.3e-122 ftsE D cell division ATP-binding protein FtsE
EKFNCIHE_03409 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
EKFNCIHE_03410 3e-148 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
EKFNCIHE_03411 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EKFNCIHE_03412 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EKFNCIHE_03413 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EKFNCIHE_03414 6.8e-68
EKFNCIHE_03415 4.5e-10 fliT S bacterial-type flagellum organization
EKFNCIHE_03416 3e-66 fliS N flagellar protein FliS
EKFNCIHE_03417 8.9e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EKFNCIHE_03418 4.2e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EKFNCIHE_03419 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EKFNCIHE_03420 7.2e-74 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EKFNCIHE_03421 1.5e-79 yviE
EKFNCIHE_03422 2.3e-162 flgL N Belongs to the bacterial flagellin family
EKFNCIHE_03423 3.1e-273 flgK N flagellar hook-associated protein
EKFNCIHE_03424 3.4e-80 flgN NOU FlgN protein
EKFNCIHE_03425 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
EKFNCIHE_03426 4.1e-74 yvyF S flagellar protein
EKFNCIHE_03427 2.9e-76 comFC S Phosphoribosyl transferase domain
EKFNCIHE_03428 1.7e-42 comFB S Late competence development protein ComFB
EKFNCIHE_03429 1.3e-254 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EKFNCIHE_03430 1.9e-158 degV S protein conserved in bacteria
EKFNCIHE_03431 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFNCIHE_03432 3.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EKFNCIHE_03433 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
EKFNCIHE_03434 1e-165 yvhJ K Transcriptional regulator
EKFNCIHE_03435 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EKFNCIHE_03436 3.3e-233 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
EKFNCIHE_03437 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
EKFNCIHE_03438 7.3e-113 tuaF M protein involved in exopolysaccharide biosynthesis
EKFNCIHE_03439 8.9e-254 tuaE M Teichuronic acid biosynthesis protein
EKFNCIHE_03440 3.8e-246 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKFNCIHE_03441 2.3e-223 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
EKFNCIHE_03442 3.5e-258 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKFNCIHE_03443 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EKFNCIHE_03444 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EKFNCIHE_03445 0.0 lytB 3.5.1.28 D Stage II sporulation protein
EKFNCIHE_03446 2.3e-48
EKFNCIHE_03447 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EKFNCIHE_03448 4.5e-208 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EKFNCIHE_03449 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EKFNCIHE_03450 5.4e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EKFNCIHE_03451 1.7e-151 tagG GM Transport permease protein
EKFNCIHE_03452 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EKFNCIHE_03453 7.8e-280 M Glycosyltransferase like family 2
EKFNCIHE_03454 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
EKFNCIHE_03455 3.8e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EKFNCIHE_03456 1.6e-216 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EKFNCIHE_03457 9.7e-238 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EKFNCIHE_03458 7.7e-185 pmi 5.3.1.8 G mannose-6-phosphate isomerase
EKFNCIHE_03459 9.7e-264 gerBA EG Spore germination protein
EKFNCIHE_03460 7.8e-197 gerBB E Spore germination protein
EKFNCIHE_03461 2.2e-210 gerAC S Spore germination protein
EKFNCIHE_03462 1.5e-266 GT2,GT4 J Glycosyl transferase family 2
EKFNCIHE_03463 4.9e-249 ywtG EGP Major facilitator Superfamily
EKFNCIHE_03464 7.2e-178 ywtF K Transcriptional regulator
EKFNCIHE_03465 4.7e-157 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
EKFNCIHE_03466 2.3e-32 yttA 2.7.13.3 S Pfam Transposase IS66
EKFNCIHE_03467 3.3e-236 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EKFNCIHE_03468 1.3e-20 ywtC
EKFNCIHE_03469 9.8e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EKFNCIHE_03470 2.3e-70 pgsC S biosynthesis protein
EKFNCIHE_03471 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
EKFNCIHE_03472 7.7e-184 gerKA EG Spore germination protein
EKFNCIHE_03473 8.2e-191 gerKB E Spore germination protein
EKFNCIHE_03474 7.4e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
EKFNCIHE_03475 1.1e-178 rbsR K transcriptional
EKFNCIHE_03476 2.5e-42 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKFNCIHE_03477 2.5e-101 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKFNCIHE_03478 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EKFNCIHE_03479 1.9e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EKFNCIHE_03480 6.5e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
EKFNCIHE_03481 7.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
EKFNCIHE_03482 1.5e-89 batE T Sh3 type 3 domain protein
EKFNCIHE_03483 2e-94 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
EKFNCIHE_03484 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
EKFNCIHE_03485 2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EKFNCIHE_03486 2.6e-166 alsR K LysR substrate binding domain
EKFNCIHE_03488 2.7e-236 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EKFNCIHE_03489 7.5e-126 ywrJ
EKFNCIHE_03490 2.8e-128 cotB
EKFNCIHE_03491 1.1e-211 cotH M Spore Coat
EKFNCIHE_03492 2e-09
EKFNCIHE_03493 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EKFNCIHE_03495 5e-298 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
EKFNCIHE_03496 2.5e-83 ywrC K Transcriptional regulator
EKFNCIHE_03497 9.5e-101 ywrB P Chromate transporter
EKFNCIHE_03498 1.9e-87 ywrA P COG2059 Chromate transport protein ChrA
EKFNCIHE_03500 3.3e-92 ywqN S NAD(P)H-dependent
EKFNCIHE_03501 3.1e-156 K Transcriptional regulator
EKFNCIHE_03502 1.1e-130 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
EKFNCIHE_03503 9.7e-14
EKFNCIHE_03505 3.6e-155 ywqJ S Pre-toxin TG
EKFNCIHE_03506 9e-41 S Protein of unknown function (DUF2004)
EKFNCIHE_03507 2.6e-49
EKFNCIHE_03508 7.4e-303 ywqJ S Pre-toxin TG
EKFNCIHE_03509 7.3e-37 ywqI S Family of unknown function (DUF5344)
EKFNCIHE_03510 1.4e-21 S Domain of unknown function (DUF5082)
EKFNCIHE_03511 5.3e-147 ywqG S Domain of unknown function (DUF1963)
EKFNCIHE_03512 1.3e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKFNCIHE_03513 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
EKFNCIHE_03514 1.6e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
EKFNCIHE_03515 1.8e-109 ywqC M biosynthesis protein
EKFNCIHE_03516 1.3e-14
EKFNCIHE_03517 4.6e-307 ywqB S SWIM zinc finger
EKFNCIHE_03518 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
EKFNCIHE_03519 6.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
EKFNCIHE_03520 7.5e-138 glcR K DeoR C terminal sensor domain
EKFNCIHE_03521 3.7e-57 ssbB L Single-stranded DNA-binding protein
EKFNCIHE_03522 4e-62 ywpG
EKFNCIHE_03523 2.5e-68 ywpF S YwpF-like protein
EKFNCIHE_03524 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EKFNCIHE_03525 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EKFNCIHE_03526 5.2e-198 S aspartate phosphatase
EKFNCIHE_03527 7e-142 flhP N flagellar basal body
EKFNCIHE_03528 3.2e-128 flhO N flagellar basal body
EKFNCIHE_03529 2.7e-180 mbl D Rod shape-determining protein
EKFNCIHE_03530 1.8e-44 spoIIID K Stage III sporulation protein D
EKFNCIHE_03531 2.5e-71 ywoH K transcriptional
EKFNCIHE_03532 1.4e-212 ywoG EGP Major facilitator Superfamily
EKFNCIHE_03533 1.3e-273 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
EKFNCIHE_03534 1e-243 ywoD EGP Major facilitator superfamily
EKFNCIHE_03535 4.8e-102 phzA Q Isochorismatase family
EKFNCIHE_03536 2.5e-228 amt P Ammonium transporter
EKFNCIHE_03537 2e-58 nrgB K Belongs to the P(II) protein family
EKFNCIHE_03538 3.9e-207 ftsW D Belongs to the SEDS family
EKFNCIHE_03539 5.4e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
EKFNCIHE_03540 5.6e-71 ywnJ S VanZ like family
EKFNCIHE_03541 1.4e-121 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
EKFNCIHE_03542 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
EKFNCIHE_03543 1.2e-10 ywnC S Family of unknown function (DUF5362)
EKFNCIHE_03544 4.2e-69 ywnF S Family of unknown function (DUF5392)
EKFNCIHE_03545 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKFNCIHE_03546 1.2e-51 ywnC S Family of unknown function (DUF5362)
EKFNCIHE_03547 2e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
EKFNCIHE_03548 6.1e-67 ywnA K Transcriptional regulator
EKFNCIHE_03549 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EKFNCIHE_03550 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
EKFNCIHE_03551 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
EKFNCIHE_03552 1.4e-10 csbD K CsbD-like
EKFNCIHE_03553 2.3e-81 ywmF S Peptidase M50
EKFNCIHE_03554 2.8e-93 S response regulator aspartate phosphatase
EKFNCIHE_03555 4.1e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EKFNCIHE_03556 2.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EKFNCIHE_03558 6.6e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
EKFNCIHE_03559 1.1e-113 ywmC S protein containing a von Willebrand factor type A (vWA) domain
EKFNCIHE_03560 4e-179 spoIID D Stage II sporulation protein D
EKFNCIHE_03561 1.1e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKFNCIHE_03562 2.2e-134 ywmB S TATA-box binding
EKFNCIHE_03563 4.8e-32 ywzB S membrane
EKFNCIHE_03564 8.7e-89 ywmA
EKFNCIHE_03565 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EKFNCIHE_03566 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EKFNCIHE_03567 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EKFNCIHE_03568 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EKFNCIHE_03569 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKFNCIHE_03570 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EKFNCIHE_03571 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKFNCIHE_03572 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
EKFNCIHE_03573 2.1e-61 atpI S ATP synthase
EKFNCIHE_03574 2.3e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EKFNCIHE_03575 5.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EKFNCIHE_03576 5e-96 ywlG S Belongs to the UPF0340 family
EKFNCIHE_03577 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
EKFNCIHE_03578 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EKFNCIHE_03579 1.3e-83 mntP P Probably functions as a manganese efflux pump
EKFNCIHE_03580 3.3e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EKFNCIHE_03581 8.8e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
EKFNCIHE_03582 8.9e-119 spoIIR S stage II sporulation protein R
EKFNCIHE_03583 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
EKFNCIHE_03585 1.1e-153 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EKFNCIHE_03586 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EKFNCIHE_03587 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKFNCIHE_03588 2.2e-94 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EKFNCIHE_03589 6.8e-157 ywkB S Membrane transport protein
EKFNCIHE_03590 0.0 sfcA 1.1.1.38 C malic enzyme
EKFNCIHE_03591 8.6e-102 tdk 2.7.1.21 F thymidine kinase
EKFNCIHE_03592 1.1e-32 rpmE J Binds the 23S rRNA
EKFNCIHE_03593 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EKFNCIHE_03594 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
EKFNCIHE_03595 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKFNCIHE_03596 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EKFNCIHE_03597 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
EKFNCIHE_03598 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
EKFNCIHE_03599 2.4e-92 ywjG S Domain of unknown function (DUF2529)
EKFNCIHE_03600 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EKFNCIHE_03601 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EKFNCIHE_03602 0.0 fadF C COG0247 Fe-S oxidoreductase
EKFNCIHE_03603 2.3e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EKFNCIHE_03604 2.9e-179 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EKFNCIHE_03605 4.2e-43 ywjC
EKFNCIHE_03606 1e-301 ywjA V ABC transporter
EKFNCIHE_03607 1.3e-295 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKFNCIHE_03608 3.4e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKFNCIHE_03609 7.2e-121 narI 1.7.5.1 C nitrate reductase, gamma
EKFNCIHE_03610 4.8e-94 narJ 1.7.5.1 C nitrate reductase
EKFNCIHE_03611 4.8e-295 narH 1.7.5.1 C Nitrate reductase, beta
EKFNCIHE_03612 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EKFNCIHE_03613 1e-84 arfM T cyclic nucleotide binding
EKFNCIHE_03614 2.8e-139 ywiC S YwiC-like protein
EKFNCIHE_03615 5e-128 fnr K helix_turn_helix, cAMP Regulatory protein
EKFNCIHE_03616 5.4e-212 narK P COG2223 Nitrate nitrite transporter
EKFNCIHE_03617 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
EKFNCIHE_03618 2.9e-43 ywiB S protein conserved in bacteria
EKFNCIHE_03619 4.4e-78 S aspartate phosphatase
EKFNCIHE_03621 3.8e-57 speB 3.5.3.11 E Belongs to the arginase family
EKFNCIHE_03623 2.3e-25 norM_1 V drug transmembrane transporter activity
EKFNCIHE_03624 3.2e-38 C Nitroreductase family
EKFNCIHE_03625 2.2e-42 C coenzyme F420-1:gamma-L-glutamate ligase activity
EKFNCIHE_03627 2.9e-227 argS 6.1.1.19 J Arginyl-tRNA synthetase
EKFNCIHE_03628 7.8e-168 speB 3.5.3.11 E Belongs to the arginase family
EKFNCIHE_03629 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EKFNCIHE_03630 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EKFNCIHE_03631 1.6e-81
EKFNCIHE_03632 8.4e-93 ywhD S YwhD family
EKFNCIHE_03633 1.2e-117 ywhC S Peptidase family M50
EKFNCIHE_03634 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
EKFNCIHE_03635 4.9e-67 ywhA K Transcriptional regulator
EKFNCIHE_03636 1.9e-245 yhdG_1 E C-terminus of AA_permease
EKFNCIHE_03637 4.6e-88 ywgA 2.1.1.72, 3.1.21.3
EKFNCIHE_03638 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
EKFNCIHE_03639 6.9e-36 ywzC S Belongs to the UPF0741 family
EKFNCIHE_03640 6.6e-110 rsfA_1
EKFNCIHE_03641 9.7e-52 padR K PadR family transcriptional regulator
EKFNCIHE_03642 3.4e-92 S membrane
EKFNCIHE_03643 2.1e-40 V ABC transporter, ATP-binding protein
EKFNCIHE_03644 4.4e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EKFNCIHE_03645 3e-162 cysL K Transcriptional regulator
EKFNCIHE_03646 4e-157 MA20_14895 S Conserved hypothetical protein 698
EKFNCIHE_03647 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
EKFNCIHE_03648 3.3e-146 ywfI C May function as heme-dependent peroxidase
EKFNCIHE_03649 5.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
EKFNCIHE_03650 1.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
EKFNCIHE_03651 4e-207 bacE EGP Major facilitator Superfamily
EKFNCIHE_03652 1.4e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EKFNCIHE_03653 8.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFNCIHE_03654 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EKFNCIHE_03655 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EKFNCIHE_03656 7.8e-222 ywfA EGP Major facilitator Superfamily
EKFNCIHE_03657 8.4e-205 tcaB EGP Major facilitator Superfamily
EKFNCIHE_03658 4.5e-258 lysP E amino acid
EKFNCIHE_03659 0.0 rocB E arginine degradation protein
EKFNCIHE_03660 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
EKFNCIHE_03661 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
EKFNCIHE_03662 1.9e-59
EKFNCIHE_03663 3e-86 spsL 5.1.3.13 M Spore Coat
EKFNCIHE_03664 4e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EKFNCIHE_03665 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EKFNCIHE_03666 1.3e-136 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EKFNCIHE_03667 3.3e-178 spsG M Spore Coat
EKFNCIHE_03668 2.6e-132 spsF M Spore Coat
EKFNCIHE_03669 3.8e-215 spsE 2.5.1.56 M acid synthase
EKFNCIHE_03670 1.2e-155 spsD 2.3.1.210 K Spore Coat
EKFNCIHE_03671 4e-220 spsC E Belongs to the DegT DnrJ EryC1 family
EKFNCIHE_03672 9.1e-275 spsB M Capsule polysaccharide biosynthesis protein
EKFNCIHE_03673 1.7e-142 spsA M Spore Coat
EKFNCIHE_03674 4e-61 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EKFNCIHE_03675 4.2e-46 ywdK S small membrane protein
EKFNCIHE_03676 5.4e-229 ywdJ F Xanthine uracil
EKFNCIHE_03677 4.7e-41 ywdI S Family of unknown function (DUF5327)
EKFNCIHE_03678 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EKFNCIHE_03679 1.8e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
EKFNCIHE_03681 1.3e-87 ywdD
EKFNCIHE_03682 6.3e-57 pex K Transcriptional regulator PadR-like family
EKFNCIHE_03683 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EKFNCIHE_03684 7.4e-20 ywdA
EKFNCIHE_03685 6.4e-284 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
EKFNCIHE_03686 5.8e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EKFNCIHE_03687 3.7e-151 sacT K transcriptional antiterminator
EKFNCIHE_03689 0.0 vpr O Belongs to the peptidase S8 family
EKFNCIHE_03690 8.9e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFNCIHE_03691 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
EKFNCIHE_03692 8e-208 rodA D Belongs to the SEDS family
EKFNCIHE_03693 1.7e-76 ysnE K acetyltransferase
EKFNCIHE_03694 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
EKFNCIHE_03695 2.4e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
EKFNCIHE_03696 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
EKFNCIHE_03697 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EKFNCIHE_03698 4.1e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EKFNCIHE_03699 8.4e-27 ywzA S membrane
EKFNCIHE_03700 1.2e-293 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EKFNCIHE_03701 5.1e-61 gtcA S GtrA-like protein
EKFNCIHE_03702 1.3e-111 ywcC K Bacterial regulatory proteins, tetR family
EKFNCIHE_03704 7.3e-129 H Methionine biosynthesis protein MetW
EKFNCIHE_03705 1.2e-131 S Streptomycin biosynthesis protein StrF
EKFNCIHE_03706 3e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
EKFNCIHE_03707 1.4e-242 ywbN P Dyp-type peroxidase family protein
EKFNCIHE_03708 1.1e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EKFNCIHE_03709 4.8e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EKFNCIHE_03710 8.2e-152 ywbI K Transcriptional regulator
EKFNCIHE_03711 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EKFNCIHE_03712 1.3e-109 ywbG M effector of murein hydrolase
EKFNCIHE_03713 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
EKFNCIHE_03714 1.1e-136 mta K transcriptional
EKFNCIHE_03715 1e-223 ywbD 2.1.1.191 J Methyltransferase
EKFNCIHE_03716 7.6e-67 ywbC 4.4.1.5 E glyoxalase
EKFNCIHE_03717 5.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKFNCIHE_03718 5.4e-261 epr 3.4.21.62 O Belongs to the peptidase S8 family
EKFNCIHE_03719 4.1e-161 gspA M General stress
EKFNCIHE_03720 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
EKFNCIHE_03721 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
EKFNCIHE_03722 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
EKFNCIHE_03723 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFNCIHE_03724 4.8e-229 dltB M membrane protein involved in D-alanine export
EKFNCIHE_03725 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFNCIHE_03726 3.8e-226 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EKFNCIHE_03727 1.9e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EKFNCIHE_03728 1e-251 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EKFNCIHE_03729 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
EKFNCIHE_03730 7.4e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKFNCIHE_03731 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
EKFNCIHE_03732 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
EKFNCIHE_03733 2.3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
EKFNCIHE_03734 2.8e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFNCIHE_03735 7.9e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFNCIHE_03736 1.5e-166 cbrA3 P Periplasmic binding protein
EKFNCIHE_03737 1.7e-57 arsR K transcriptional
EKFNCIHE_03738 2.5e-226 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EKFNCIHE_03739 5.8e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
EKFNCIHE_03740 2.3e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
EKFNCIHE_03741 5.4e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKFNCIHE_03742 2.4e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EKFNCIHE_03743 1.2e-163 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
EKFNCIHE_03744 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
EKFNCIHE_03745 2.7e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
EKFNCIHE_03746 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
EKFNCIHE_03747 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
EKFNCIHE_03748 7.9e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
EKFNCIHE_03749 4.7e-154 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EKFNCIHE_03750 1.3e-291 cydD V ATP-binding protein
EKFNCIHE_03751 0.0 cydD V ATP-binding
EKFNCIHE_03752 2.5e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
EKFNCIHE_03753 5e-265 cydA 1.10.3.14 C oxidase, subunit
EKFNCIHE_03754 5e-214 cimH C COG3493 Na citrate symporter
EKFNCIHE_03755 4.3e-155 yxkH G Polysaccharide deacetylase
EKFNCIHE_03756 2.6e-205 msmK P Belongs to the ABC transporter superfamily
EKFNCIHE_03757 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
EKFNCIHE_03758 3.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKFNCIHE_03759 3.8e-87 yxkC S Domain of unknown function (DUF4352)
EKFNCIHE_03760 2.8e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EKFNCIHE_03761 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EKFNCIHE_03764 2e-85 yxjI S LURP-one-related
EKFNCIHE_03765 1.8e-217 yxjG 2.1.1.14 E Methionine synthase
EKFNCIHE_03766 6.5e-154 rlmA 2.1.1.187 Q Methyltransferase domain
EKFNCIHE_03767 2.3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKFNCIHE_03768 1.8e-71 T Domain of unknown function (DUF4163)
EKFNCIHE_03769 1.5e-49 yxiS
EKFNCIHE_03770 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
EKFNCIHE_03771 3.1e-221 citH C Citrate transporter
EKFNCIHE_03772 2e-140 exoK GH16 M licheninase activity
EKFNCIHE_03774 1e-106 licT K transcriptional antiterminator
EKFNCIHE_03775 5.1e-221 yxiO S COG2270 Permeases of the major facilitator superfamily
EKFNCIHE_03776 6.9e-262 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EKFNCIHE_03779 1.2e-61 S SMI1-KNR4 cell-wall
EKFNCIHE_03780 1.6e-48 yxiI S Protein of unknown function (DUF2716)
EKFNCIHE_03781 1.3e-20
EKFNCIHE_03782 1.3e-13 S YxiJ-like protein
EKFNCIHE_03783 2.7e-109
EKFNCIHE_03784 4.6e-79
EKFNCIHE_03785 8.6e-69 yxiG
EKFNCIHE_03786 1.2e-44 yxxG
EKFNCIHE_03787 1.2e-199 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
EKFNCIHE_03788 4.7e-147 yxxF EG EamA-like transporter family
EKFNCIHE_03789 1.8e-72 yxiE T Belongs to the universal stress protein A family
EKFNCIHE_03792 2.5e-64 K Transcriptional regulator
EKFNCIHE_03794 9e-25
EKFNCIHE_03795 7e-102 L Replication protein
EKFNCIHE_03796 1.1e-13 S Domain of unknown function (DUF5082)
EKFNCIHE_03797 5.1e-45 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
EKFNCIHE_03798 1.9e-182 2.1.1.37 H C-5 cytosine-specific DNA methylase
EKFNCIHE_03799 2e-180 L AlwI restriction endonuclease
EKFNCIHE_03800 8.4e-09
EKFNCIHE_03801 5.3e-275 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
EKFNCIHE_03802 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EKFNCIHE_03803 1.8e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
EKFNCIHE_03804 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EKFNCIHE_03805 1.4e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
EKFNCIHE_03806 4.7e-174 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EKFNCIHE_03807 4.4e-253 lysP E amino acid
EKFNCIHE_03808 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
EKFNCIHE_03809 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKFNCIHE_03810 3.6e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EKFNCIHE_03811 9.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EKFNCIHE_03812 2.6e-149 yidA S hydrolases of the HAD superfamily
EKFNCIHE_03816 8.4e-23 yxeD
EKFNCIHE_03817 1.3e-34
EKFNCIHE_03818 4.1e-178 fhuD P Periplasmic binding protein
EKFNCIHE_03819 1.3e-57 yxeA S Protein of unknown function (DUF1093)
EKFNCIHE_03820 0.0 yxdM V ABC transporter (permease)
EKFNCIHE_03821 3.6e-140 yxdL V ABC transporter, ATP-binding protein
EKFNCIHE_03822 3.5e-177 T PhoQ Sensor
EKFNCIHE_03823 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFNCIHE_03824 1.8e-156 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EKFNCIHE_03825 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EKFNCIHE_03826 3.3e-166 iolH G Xylose isomerase-like TIM barrel
EKFNCIHE_03827 2.6e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EKFNCIHE_03828 6.7e-232 iolF EGP Major facilitator Superfamily
EKFNCIHE_03829 3.4e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EKFNCIHE_03830 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EKFNCIHE_03831 2.7e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EKFNCIHE_03832 1.6e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EKFNCIHE_03833 4.8e-279 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EKFNCIHE_03834 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
EKFNCIHE_03835 1.2e-174 iolS C Aldo keto reductase
EKFNCIHE_03836 1.9e-245 csbC EGP Major facilitator Superfamily
EKFNCIHE_03837 0.0 htpG O Molecular chaperone. Has ATPase activity
EKFNCIHE_03839 6.9e-150 IQ Enoyl-(Acyl carrier protein) reductase
EKFNCIHE_03840 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFNCIHE_03841 4.5e-200 desK 2.7.13.3 T Histidine kinase
EKFNCIHE_03842 9.6e-197 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
EKFNCIHE_03843 6.2e-213 yxbF K Bacterial regulatory proteins, tetR family
EKFNCIHE_03844 3.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
EKFNCIHE_03845 1.1e-141 S PQQ-like domain
EKFNCIHE_03846 1.7e-64 S Family of unknown function (DUF5391)
EKFNCIHE_03847 3e-50 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
EKFNCIHE_03848 1.3e-199 EGP Major facilitator Superfamily
EKFNCIHE_03849 3.8e-73 yxaI S membrane protein domain
EKFNCIHE_03850 2.2e-125 E Ring-cleavage extradiol dioxygenase
EKFNCIHE_03851 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
EKFNCIHE_03852 2.3e-287 ahpF O Alkyl hydroperoxide reductase
EKFNCIHE_03853 1.6e-244 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
EKFNCIHE_03854 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
EKFNCIHE_03855 1.3e-81 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EKFNCIHE_03856 2.6e-152 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EKFNCIHE_03857 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EKFNCIHE_03858 7.4e-88 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
EKFNCIHE_03859 1.8e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EKFNCIHE_03860 7.5e-173 S Fusaric acid resistance protein-like
EKFNCIHE_03861 1.3e-23 V Domain of unknown function (DUF3883)
EKFNCIHE_03863 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EKFNCIHE_03864 7.9e-08 S YyzF-like protein
EKFNCIHE_03866 3e-215 yycP
EKFNCIHE_03867 2.7e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EKFNCIHE_03868 3.1e-181 C oxidoreductases (related to aryl-alcohol dehydrogenases)
EKFNCIHE_03869 1.4e-86 yycN 2.3.1.128 K Acetyltransferase
EKFNCIHE_03871 2.2e-199 S Histidine kinase
EKFNCIHE_03872 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
EKFNCIHE_03873 3.8e-257 rocE E amino acid
EKFNCIHE_03874 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
EKFNCIHE_03875 7.7e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EKFNCIHE_03876 5.9e-145 1.14.11.27 P peptidyl-arginine hydroxylation
EKFNCIHE_03877 1.3e-304 S ABC transporter
EKFNCIHE_03878 4.5e-195 S Major Facilitator Superfamily
EKFNCIHE_03879 1e-256
EKFNCIHE_03880 7.1e-189 2.7.7.73, 2.7.7.80 H ThiF family
EKFNCIHE_03881 5.6e-248 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
EKFNCIHE_03882 2.8e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFNCIHE_03883 3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKFNCIHE_03884 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EKFNCIHE_03885 1.1e-150 yycI S protein conserved in bacteria
EKFNCIHE_03886 2.5e-261 yycH S protein conserved in bacteria
EKFNCIHE_03887 0.0 vicK 2.7.13.3 T Histidine kinase
EKFNCIHE_03888 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFNCIHE_03893 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EKFNCIHE_03894 4.2e-71 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKFNCIHE_03895 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EKFNCIHE_03896 5.7e-26 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
EKFNCIHE_03898 4.6e-17 yycC K YycC-like protein
EKFNCIHE_03899 2.2e-235 M Glycosyltransferase Family 4
EKFNCIHE_03900 2.4e-203 S Ecdysteroid kinase
EKFNCIHE_03901 2.5e-233 S Carbamoyl-phosphate synthase L chain, ATP binding domain
EKFNCIHE_03902 1.6e-241 M Glycosyltransferase Family 4
EKFNCIHE_03903 1.1e-121 S GlcNAc-PI de-N-acetylase
EKFNCIHE_03904 8.2e-102 KLT COG0515 Serine threonine protein kinase
EKFNCIHE_03905 4.9e-73 rplI J binds to the 23S rRNA
EKFNCIHE_03906 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EKFNCIHE_03907 1.2e-158 yybS S membrane
EKFNCIHE_03909 2.1e-83 cotF M Spore coat protein
EKFNCIHE_03910 8.2e-66 ydeP3 K Transcriptional regulator
EKFNCIHE_03911 5e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
EKFNCIHE_03912 5.3e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EKFNCIHE_03913 2.9e-273 sacB 2.4.1.10 GH68 M levansucrase activity
EKFNCIHE_03914 4.3e-311 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
EKFNCIHE_03915 2.2e-114 K FCD domain
EKFNCIHE_03916 1.8e-71 dinB S PFAM DinB family protein
EKFNCIHE_03917 3.2e-159 G Major Facilitator Superfamily
EKFNCIHE_03918 2.2e-55 ypaA S Protein of unknown function (DUF1304)
EKFNCIHE_03919 5.6e-115 drgA C nitroreductase
EKFNCIHE_03920 4.1e-69 ydgJ K Winged helix DNA-binding domain
EKFNCIHE_03921 3.9e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
EKFNCIHE_03922 1.6e-76 yybA 2.3.1.57 K transcriptional
EKFNCIHE_03923 1.4e-41 yjcF S Acetyltransferase (GNAT) domain
EKFNCIHE_03925 2.4e-161 eaeH M Domain of Unknown Function (DUF1259)
EKFNCIHE_03926 8.8e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
EKFNCIHE_03927 8.6e-162 K Transcriptional regulator
EKFNCIHE_03928 3.9e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EKFNCIHE_03929 9.4e-251 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKFNCIHE_03930 2.1e-131 ydfC EG EamA-like transporter family
EKFNCIHE_03931 1.1e-99 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EKFNCIHE_03932 2.8e-77 K Transcriptional regulator
EKFNCIHE_03933 7.6e-14 yvaO K Transcriptional
EKFNCIHE_03934 2.7e-40 qacC U Small Multidrug Resistance protein
EKFNCIHE_03935 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
EKFNCIHE_03936 7.3e-161 yyaK S CAAX protease self-immunity
EKFNCIHE_03937 5.8e-247 ydjK G Sugar (and other) transporter
EKFNCIHE_03938 9.9e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKFNCIHE_03939 5.2e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
EKFNCIHE_03940 6e-140 xth 3.1.11.2 L exodeoxyribonuclease III
EKFNCIHE_03941 2.7e-97 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKFNCIHE_03942 4.8e-105 adaA 3.2.2.21 K Transcriptional regulator
EKFNCIHE_03943 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EKFNCIHE_03944 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EKFNCIHE_03945 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
EKFNCIHE_03946 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EKFNCIHE_03947 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EKFNCIHE_03948 2.3e-33 yyzM S protein conserved in bacteria
EKFNCIHE_03949 2.4e-176 yyaD S Membrane
EKFNCIHE_03950 6.2e-111 yyaC S Sporulation protein YyaC
EKFNCIHE_03951 7.9e-149 spo0J K Belongs to the ParB family
EKFNCIHE_03952 2.6e-135 soj D COG1192 ATPases involved in chromosome partitioning
EKFNCIHE_03953 3.8e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EKFNCIHE_03954 1.6e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EKFNCIHE_03955 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EKFNCIHE_03956 1.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EKFNCIHE_03957 1.3e-108 jag S single-stranded nucleic acid binding R3H
EKFNCIHE_03958 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EKFNCIHE_03959 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)