ORF_ID e_value Gene_name EC_number CAZy COGs Description
MDEDNEIO_00001 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MDEDNEIO_00002 7.9e-113 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
MDEDNEIO_00003 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDEDNEIO_00004 1e-148 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
MDEDNEIO_00005 6.3e-150 yecS E Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00006 2.1e-158 pknD ET ABC transporter, substrate-binding protein, family 3
MDEDNEIO_00007 2.1e-129 pknD ET ABC transporter, substrate-binding protein, family 3
MDEDNEIO_00008 1.8e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MDEDNEIO_00009 4.2e-152 usp 3.5.1.28 CBM50 D CHAP domain protein
MDEDNEIO_00010 5.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
MDEDNEIO_00011 1e-175 ftsE D Cell division ATP-binding protein FtsE
MDEDNEIO_00012 7.1e-206 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDEDNEIO_00013 1.1e-253 S Domain of unknown function (DUF4143)
MDEDNEIO_00014 1.4e-273 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
MDEDNEIO_00015 3.4e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDEDNEIO_00016 7.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDEDNEIO_00017 1.2e-97 ugpA P Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00018 1.3e-97 ugpE G Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00019 4.2e-160 ugpB G Bacterial extracellular solute-binding protein
MDEDNEIO_00020 1.5e-99 ugpQ 3.1.4.46 C Domain of unknown function
MDEDNEIO_00021 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
MDEDNEIO_00022 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDEDNEIO_00023 1e-165 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDEDNEIO_00024 1.7e-131 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MDEDNEIO_00025 1.5e-226 G Major Facilitator Superfamily
MDEDNEIO_00026 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
MDEDNEIO_00027 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
MDEDNEIO_00028 4.9e-260 KLT Protein tyrosine kinase
MDEDNEIO_00029 0.0 S Fibronectin type 3 domain
MDEDNEIO_00030 2.4e-176 S ATPase family associated with various cellular activities (AAA)
MDEDNEIO_00031 9.1e-223 S Protein of unknown function DUF58
MDEDNEIO_00032 0.0 E Transglutaminase-like superfamily
MDEDNEIO_00033 2.1e-25 3.1.3.16 T Sigma factor PP2C-like phosphatases
MDEDNEIO_00034 3e-70 B Belongs to the OprB family
MDEDNEIO_00035 1.1e-86 T Forkhead associated domain
MDEDNEIO_00036 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDEDNEIO_00037 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDEDNEIO_00038 2.9e-107
MDEDNEIO_00039 9.4e-183 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
MDEDNEIO_00040 2.6e-115 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDEDNEIO_00041 9.5e-40 DJ ParE toxin of type II toxin-antitoxin system, parDE
MDEDNEIO_00042 2.6e-33 S CopG domain protein DNA-binding domain protein
MDEDNEIO_00044 4.5e-20 Q Belongs to the P-Pant transferase superfamily
MDEDNEIO_00045 3.6e-124 ydjK G Sugar (and other) transporter
MDEDNEIO_00046 2.6e-222 hsvB 6.3.2.4 M Belongs to the D-alanine--D-alanine ligase family
MDEDNEIO_00047 3.4e-45 nrpS1 Q TIGRFAM amino acid adenylation domain
MDEDNEIO_00048 1.4e-23 Q Non-ribosomal peptide synthetase modules and related proteins
MDEDNEIO_00049 4.9e-216 P Major Facilitator Superfamily
MDEDNEIO_00050 4e-41 S ATPase domain predominantly from Archaea
MDEDNEIO_00051 1e-23 S ATPase domain predominantly from Archaea
MDEDNEIO_00052 5.9e-135 S ATPase domain predominantly from Archaea
MDEDNEIO_00053 1.2e-250 S UPF0210 protein
MDEDNEIO_00054 1.9e-43 gcvR T Belongs to the UPF0237 family
MDEDNEIO_00055 1.4e-16 EGP Major facilitator Superfamily
MDEDNEIO_00056 5.4e-231 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
MDEDNEIO_00057 8.6e-253 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
MDEDNEIO_00058 1.2e-121 glpR K DeoR C terminal sensor domain
MDEDNEIO_00059 2.8e-226 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MDEDNEIO_00060 6.6e-238 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
MDEDNEIO_00061 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MDEDNEIO_00062 1.7e-132 glxR K helix_turn_helix, cAMP Regulatory protein
MDEDNEIO_00063 1.4e-198 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
MDEDNEIO_00064 2.4e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MDEDNEIO_00065 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
MDEDNEIO_00066 3.3e-250 S Uncharacterized conserved protein (DUF2183)
MDEDNEIO_00067 1.2e-70 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MDEDNEIO_00068 1.5e-228 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
MDEDNEIO_00069 1.5e-160 mhpC I Alpha/beta hydrolase family
MDEDNEIO_00070 7.3e-126 F Domain of unknown function (DUF4916)
MDEDNEIO_00071 1.9e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
MDEDNEIO_00072 6.7e-168 S G5
MDEDNEIO_00073 3.9e-19 hipB K Helix-turn-helix XRE-family like proteins
MDEDNEIO_00074 3.3e-133 2.7.11.1 S HipA-like C-terminal domain
MDEDNEIO_00075 8.6e-145
MDEDNEIO_00076 1.1e-277 L PFAM Integrase catalytic
MDEDNEIO_00077 3.1e-155 2.7.7.7 L Transposase, Mutator family
MDEDNEIO_00078 7.5e-237 wcoI DM Psort location CytoplasmicMembrane, score
MDEDNEIO_00080 6.2e-165 dprA LU DNA recombination-mediator protein A
MDEDNEIO_00081 5.8e-160 S competence protein
MDEDNEIO_00082 2.3e-101 S PIN domain
MDEDNEIO_00083 1.3e-140
MDEDNEIO_00084 9.6e-09
MDEDNEIO_00085 3.3e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MDEDNEIO_00086 1.6e-266 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MDEDNEIO_00087 6.9e-200 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MDEDNEIO_00088 1.1e-10 L PFAM Integrase catalytic
MDEDNEIO_00089 5.1e-167 M Domain of unknown function (DUF1972)
MDEDNEIO_00090 8.3e-201 M Glycosyl transferase 4-like domain
MDEDNEIO_00091 3.9e-161 lspL 5.1.3.6 GM Polysaccharide biosynthesis protein
MDEDNEIO_00092 3.8e-216 1.1.1.22 M UDP binding domain
MDEDNEIO_00093 8.9e-65 M Glycosyl transferases group 1
MDEDNEIO_00094 4.3e-107 1.1.1.339 GM GDP-mannose 4,6 dehydratase
MDEDNEIO_00095 4.7e-60 2.3.1.30 E Hexapeptide repeat of succinyl-transferase
MDEDNEIO_00096 1.6e-159 MA20_43635 M Capsular polysaccharide synthesis protein
MDEDNEIO_00097 3.1e-06 S Psort location CytoplasmicMembrane, score 10.00
MDEDNEIO_00098 4e-29 GT8 S Protein conserved in bacteria
MDEDNEIO_00099 1e-113 cps4J S Polysaccharide biosynthesis protein
MDEDNEIO_00100 6.1e-18 capG S Bacterial transferase hexapeptide (six repeats)
MDEDNEIO_00101 3.3e-113 wbiB 5.1.3.25 GM 3-beta hydroxysteroid dehydrogenase/isomerase family
MDEDNEIO_00102 1.2e-32 GM Bacterial transferase hexapeptide (six repeats)
MDEDNEIO_00103 2e-134 L Transposase
MDEDNEIO_00105 1.3e-113 S Psort location CytoplasmicMembrane, score 9.99
MDEDNEIO_00106 1.2e-106 3.1.3.48 T Low molecular weight phosphatase family
MDEDNEIO_00107 1.9e-234 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MDEDNEIO_00108 5e-108 K Bacterial regulatory proteins, tetR family
MDEDNEIO_00109 3.3e-124 V ABC transporter
MDEDNEIO_00110 0.0 V FtsX-like permease family
MDEDNEIO_00111 5.7e-258 S Domain of unknown function (DUF4143)
MDEDNEIO_00113 7.8e-96 effR K helix_turn_helix multiple antibiotic resistance protein
MDEDNEIO_00114 3.4e-132 C FMN binding
MDEDNEIO_00115 3.7e-95 S AAA domain
MDEDNEIO_00116 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
MDEDNEIO_00117 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MDEDNEIO_00118 1.1e-242 vbsD V MatE
MDEDNEIO_00119 1.9e-116 magIII L endonuclease III
MDEDNEIO_00121 1.6e-83 laaE K Transcriptional regulator PadR-like family
MDEDNEIO_00122 1.3e-32 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MDEDNEIO_00123 2.8e-175 S Membrane transport protein
MDEDNEIO_00124 3.6e-34 uidA 3.2.1.31 G Glycosyl hydrolases family 2, TIM barrel domain
MDEDNEIO_00125 5e-281 glnA 6.3.1.2 E glutamine synthetase
MDEDNEIO_00126 1.1e-139 S Domain of unknown function (DUF4191)
MDEDNEIO_00127 3.2e-278 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MDEDNEIO_00128 4.2e-107 S Protein of unknown function (DUF3043)
MDEDNEIO_00129 5.7e-258 argE E Peptidase dimerisation domain
MDEDNEIO_00130 2.4e-107 ykoE S ABC-type cobalt transport system, permease component
MDEDNEIO_00131 1.9e-275 ykoD P ATPases associated with a variety of cellular activities
MDEDNEIO_00132 4.2e-147 cbiQ P Cobalt transport protein
MDEDNEIO_00133 1.5e-158 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDEDNEIO_00134 3.8e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDEDNEIO_00135 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
MDEDNEIO_00136 2.6e-94
MDEDNEIO_00137 1.6e-202 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MDEDNEIO_00138 3.1e-212 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MDEDNEIO_00139 3.5e-160 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MDEDNEIO_00140 1.5e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
MDEDNEIO_00141 8.6e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MDEDNEIO_00142 4.5e-83 argR K Regulates arginine biosynthesis genes
MDEDNEIO_00143 4.6e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MDEDNEIO_00144 8.8e-281 argH 4.3.2.1 E argininosuccinate lyase
MDEDNEIO_00145 1.8e-27 thiS 2.8.1.10 H ThiS family
MDEDNEIO_00146 1.4e-156 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MDEDNEIO_00147 9.2e-147 moeB 2.7.7.80 H ThiF family
MDEDNEIO_00148 1.3e-55 M1-798 P Rhodanese Homology Domain
MDEDNEIO_00149 2.2e-96 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDEDNEIO_00150 3.1e-136 S Putative ABC-transporter type IV
MDEDNEIO_00151 7.5e-255 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDEDNEIO_00152 6.7e-137 L Tetratricopeptide repeat
MDEDNEIO_00153 1.1e-195 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MDEDNEIO_00155 7.5e-138 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MDEDNEIO_00156 2e-94
MDEDNEIO_00157 2.7e-188 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDEDNEIO_00158 7.5e-311 recN L May be involved in recombinational repair of damaged DNA
MDEDNEIO_00159 1.1e-110 S Haloacid dehalogenase-like hydrolase
MDEDNEIO_00160 3e-67 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MDEDNEIO_00161 2.7e-52 EGP Major facilitator Superfamily
MDEDNEIO_00162 1e-20 2.7.13.3 T Histidine kinase
MDEDNEIO_00163 4.8e-58 K helix_turn_helix gluconate operon transcriptional repressor
MDEDNEIO_00164 8.5e-173 V ATPases associated with a variety of cellular activities
MDEDNEIO_00165 2.9e-120 S ABC-2 family transporter protein
MDEDNEIO_00166 4.7e-71 S ABC-2 family transporter protein
MDEDNEIO_00167 8.8e-25 pacL2 3.6.3.8 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MDEDNEIO_00168 7.8e-71 K helix_turn_helix gluconate operon transcriptional repressor
MDEDNEIO_00169 3.1e-196 S Protein of unknown function (DUF1648)
MDEDNEIO_00170 2.5e-283 thrC 4.2.3.1 E Threonine synthase N terminus
MDEDNEIO_00171 9.3e-250 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDEDNEIO_00172 3.7e-230 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MDEDNEIO_00173 2.1e-100
MDEDNEIO_00174 3.8e-137 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDEDNEIO_00175 2.8e-208 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
MDEDNEIO_00176 0.0 S Uncharacterised protein family (UPF0182)
MDEDNEIO_00177 8.9e-60 2.3.1.183 M Acetyltransferase (GNAT) domain
MDEDNEIO_00178 1.4e-46 S RelB antitoxin
MDEDNEIO_00179 1.4e-72 S PIN domain
MDEDNEIO_00180 2e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDEDNEIO_00181 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDEDNEIO_00182 1.1e-180 1.1.1.65 C Aldo/keto reductase family
MDEDNEIO_00183 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDEDNEIO_00184 5e-76 divIC D Septum formation initiator
MDEDNEIO_00185 7e-101 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
MDEDNEIO_00186 1.7e-179 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MDEDNEIO_00188 9.2e-93
MDEDNEIO_00189 1.7e-276 sdaA 4.3.1.17 E Serine dehydratase alpha chain
MDEDNEIO_00190 8.9e-74 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
MDEDNEIO_00191 5.7e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDEDNEIO_00192 2.2e-131 yplQ S Haemolysin-III related
MDEDNEIO_00193 1.9e-278 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MDEDNEIO_00194 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MDEDNEIO_00195 0.0 D FtsK/SpoIIIE family
MDEDNEIO_00196 5e-164 K Cell envelope-related transcriptional attenuator domain
MDEDNEIO_00197 4.7e-56 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MDEDNEIO_00198 0.0 S Glycosyl transferase, family 2
MDEDNEIO_00199 1.5e-267
MDEDNEIO_00200 3.3e-64 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
MDEDNEIO_00201 3.7e-148 cof 5.2.1.8 T Eukaryotic phosphomannomutase
MDEDNEIO_00202 6.7e-56 ctsW S Phosphoribosyl transferase domain
MDEDNEIO_00203 3.7e-61 KT Peptidase S24-like
MDEDNEIO_00204 1.6e-191 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MDEDNEIO_00205 5e-128 T Response regulator receiver domain protein
MDEDNEIO_00206 4.5e-128 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MDEDNEIO_00207 9.9e-289 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MDEDNEIO_00208 1.6e-100 carD K CarD-like/TRCF domain
MDEDNEIO_00209 1e-90 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MDEDNEIO_00210 2e-136 znuB U ABC 3 transport family
MDEDNEIO_00211 3.1e-164 znuC P ATPases associated with a variety of cellular activities
MDEDNEIO_00212 1.1e-172 P Zinc-uptake complex component A periplasmic
MDEDNEIO_00213 4.8e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDEDNEIO_00214 8.6e-252 rpsA J Ribosomal protein S1
MDEDNEIO_00215 1e-73 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDEDNEIO_00216 5.3e-73 V ABC transporter
MDEDNEIO_00217 6.1e-144 XK27_10205
MDEDNEIO_00219 1.5e-62 K helix_turn_helix, Lux Regulon
MDEDNEIO_00220 2.5e-55 2.1.1.80, 3.1.1.61 T Histidine kinase
MDEDNEIO_00221 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDEDNEIO_00222 1.4e-165 terC P Integral membrane protein, TerC family
MDEDNEIO_00223 3.5e-274 pyk 2.7.1.40 G Pyruvate kinase
MDEDNEIO_00225 2.9e-121 pdtaR T Response regulator receiver domain protein
MDEDNEIO_00226 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDEDNEIO_00227 2.3e-178 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
MDEDNEIO_00228 7.5e-126 3.6.1.13 L NUDIX domain
MDEDNEIO_00229 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MDEDNEIO_00230 2.9e-25 zntR K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MDEDNEIO_00231 9.9e-88 K Putative zinc ribbon domain
MDEDNEIO_00232 6.7e-124 S GyrI-like small molecule binding domain
MDEDNEIO_00233 2.3e-104 tag 3.2.2.20 L Methyladenine glycosylase
MDEDNEIO_00235 7.7e-14
MDEDNEIO_00236 1.9e-22 tnp3512a L Transposase
MDEDNEIO_00237 9.6e-77 tnp3512a L Transposase
MDEDNEIO_00238 8.4e-193 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
MDEDNEIO_00239 2.4e-87 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDEDNEIO_00240 6.8e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDEDNEIO_00241 1.7e-31 S Psort location CytoplasmicMembrane, score
MDEDNEIO_00242 1.7e-185 MA20_14895 S Conserved hypothetical protein 698
MDEDNEIO_00243 1.5e-124 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
MDEDNEIO_00244 1.8e-125 tmp1 S Domain of unknown function (DUF4391)
MDEDNEIO_00245 6.8e-231 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDEDNEIO_00246 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDEDNEIO_00247 1.6e-79 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDEDNEIO_00248 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDEDNEIO_00249 2.1e-17 L Transposase and inactivated derivatives IS30 family
MDEDNEIO_00250 4.6e-19 L Helix-turn-helix domain
MDEDNEIO_00251 8e-88 V Abi-like protein
MDEDNEIO_00252 1.3e-77 L IstB-like ATP binding protein
MDEDNEIO_00253 9e-104 L PFAM Integrase catalytic
MDEDNEIO_00254 2.7e-68 V AAA domain, putative AbiEii toxin, Type IV TA system
MDEDNEIO_00255 1e-14 S ABC-2 family transporter protein
MDEDNEIO_00256 4.9e-180 yocS S SBF-like CPA transporter family (DUF4137)
MDEDNEIO_00258 1.1e-189 ltaE 4.1.2.48 E Beta-eliminating lyase
MDEDNEIO_00259 3.2e-209 M Glycosyl transferase 4-like domain
MDEDNEIO_00260 4.4e-190 mtnE 2.6.1.83 E Aminotransferase class I and II
MDEDNEIO_00261 3e-225 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MDEDNEIO_00262 3.2e-62 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDEDNEIO_00263 4.7e-137 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MDEDNEIO_00264 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
MDEDNEIO_00265 9.3e-226 I alpha/beta hydrolase fold
MDEDNEIO_00266 2.5e-253 Q D-alanine [D-alanyl carrier protein] ligase activity
MDEDNEIO_00267 9.9e-107 Q D-alanine [D-alanyl carrier protein] ligase activity
MDEDNEIO_00268 5.8e-100 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
MDEDNEIO_00269 2.5e-169 hipA 2.7.11.1 S HipA N-terminal domain
MDEDNEIO_00270 5.4e-10 C Aldo/keto reductase family
MDEDNEIO_00271 2.2e-46 C Aldo/keto reductase family
MDEDNEIO_00272 1.5e-30
MDEDNEIO_00273 1.5e-276 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
MDEDNEIO_00274 7.7e-192 3.3.1.1 H S-adenosyl-L-homocysteine hydrolase, NAD binding domain
MDEDNEIO_00275 7.8e-239 ssnA 3.5.4.40 F Amidohydrolase family
MDEDNEIO_00276 1.8e-65 MA20_39615 S Cupin superfamily (DUF985)
MDEDNEIO_00277 2.3e-127 ET Bacterial periplasmic substrate-binding proteins
MDEDNEIO_00278 1.9e-122 E Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00279 4.9e-121 glnQ 3.6.3.21 E AAA domain, putative AbiEii toxin, Type IV TA system
MDEDNEIO_00280 3.6e-285 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MDEDNEIO_00281 1.2e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MDEDNEIO_00282 1.6e-233 purD 6.3.4.13 F Belongs to the GARS family
MDEDNEIO_00283 1.7e-272 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
MDEDNEIO_00284 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
MDEDNEIO_00285 5.6e-148 P Zinc-uptake complex component A periplasmic
MDEDNEIO_00286 2.2e-97 S cobalamin synthesis protein
MDEDNEIO_00287 3.9e-29 rpmB J Ribosomal L28 family
MDEDNEIO_00288 1.4e-20 rpmG J Ribosomal protein L33
MDEDNEIO_00289 2.5e-44 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDEDNEIO_00290 4.4e-34 rpmE2 J Ribosomal protein L31
MDEDNEIO_00291 1.1e-14 rpmJ J Ribosomal protein L36
MDEDNEIO_00292 2.6e-19 J Ribosomal L32p protein family
MDEDNEIO_00293 3.9e-17 adcA P ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MDEDNEIO_00295 4e-172 ycgR S Predicted permease
MDEDNEIO_00296 8.6e-139 S TIGRFAM TIGR03943 family protein
MDEDNEIO_00297 1.1e-81 zur P Ferric uptake regulator family
MDEDNEIO_00298 4.6e-35
MDEDNEIO_00299 7.6e-46 tetR K Transcriptional regulator C-terminal region
MDEDNEIO_00300 6.7e-28 ylbB V FtsX-like permease family
MDEDNEIO_00301 1.4e-85 ylbB V FtsX-like permease family
MDEDNEIO_00302 1.2e-68 zur P Belongs to the Fur family
MDEDNEIO_00303 9.4e-225 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MDEDNEIO_00304 4.3e-86 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MDEDNEIO_00305 2.8e-177 adh3 C Zinc-binding dehydrogenase
MDEDNEIO_00306 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDEDNEIO_00307 1.4e-252 macB_8 V MacB-like periplasmic core domain
MDEDNEIO_00308 5.9e-131 M Conserved repeat domain
MDEDNEIO_00309 2.3e-123 V ATPases associated with a variety of cellular activities
MDEDNEIO_00311 1.6e-203 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MDEDNEIO_00312 6.8e-156 K Helix-turn-helix domain, rpiR family
MDEDNEIO_00313 0.0 G Alpha-L-arabinofuranosidase C-terminal domain
MDEDNEIO_00314 2.6e-28
MDEDNEIO_00315 1.2e-15 ybiR P Citrate transporter
MDEDNEIO_00316 9.1e-273 EK Alanine-glyoxylate amino-transferase
MDEDNEIO_00317 1.2e-114 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MDEDNEIO_00318 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MDEDNEIO_00319 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDEDNEIO_00320 1.2e-241 dgt 3.1.5.1 F Phosphohydrolase-associated domain
MDEDNEIO_00321 8.8e-251 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDEDNEIO_00322 7.4e-272 yhdG E aromatic amino acid transport protein AroP K03293
MDEDNEIO_00323 2.7e-102 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MDEDNEIO_00324 4.7e-93 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDEDNEIO_00325 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MDEDNEIO_00326 9.7e-292 enhA_2 S L,D-transpeptidase catalytic domain
MDEDNEIO_00327 8.8e-223 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MDEDNEIO_00328 8.3e-92 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
MDEDNEIO_00330 1.4e-171 EGP Major Facilitator Superfamily
MDEDNEIO_00331 1.4e-149 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MDEDNEIO_00332 1.6e-08 sapF E ATPases associated with a variety of cellular activities
MDEDNEIO_00333 9.6e-123 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
MDEDNEIO_00334 8.8e-125 EP Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00335 5.4e-162 P Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00336 2.4e-282 E ABC transporter, substrate-binding protein, family 5
MDEDNEIO_00337 1.3e-243 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDEDNEIO_00338 9.3e-141 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MDEDNEIO_00339 4.9e-265 G Bacterial extracellular solute-binding protein
MDEDNEIO_00340 4.6e-175 S CAAX protease self-immunity
MDEDNEIO_00341 1.2e-127 M Mechanosensitive ion channel
MDEDNEIO_00342 1.8e-270 aspA 4.3.1.1 E Fumarase C C-terminus
MDEDNEIO_00343 3.3e-135 K Bacterial regulatory proteins, tetR family
MDEDNEIO_00344 9.4e-240 MA20_36090 S Psort location Cytoplasmic, score 8.87
MDEDNEIO_00345 6.1e-85 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDEDNEIO_00346 5.8e-11 XK27_04590 S NADPH-dependent FMN reductase
MDEDNEIO_00351 2.8e-23 yxiO G Major facilitator Superfamily
MDEDNEIO_00352 2.1e-22
MDEDNEIO_00353 2e-189 K Helix-turn-helix XRE-family like proteins
MDEDNEIO_00354 8.6e-232 yxiO S Vacuole effluxer Atg22 like
MDEDNEIO_00355 1.2e-196 yegV G pfkB family carbohydrate kinase
MDEDNEIO_00356 5.5e-29 rpmB J Ribosomal L28 family
MDEDNEIO_00357 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
MDEDNEIO_00358 6.1e-97 steT E amino acid
MDEDNEIO_00360 1.3e-204
MDEDNEIO_00361 4.1e-176 U Sodium:dicarboxylate symporter family
MDEDNEIO_00362 1.2e-103 rsmD 2.1.1.171 L Conserved hypothetical protein 95
MDEDNEIO_00363 2.1e-154 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MDEDNEIO_00364 0.0 yegQ O Peptidase family U32 C-terminal domain
MDEDNEIO_00365 4.3e-183 yfiH Q Multi-copper polyphenol oxidoreductase laccase
MDEDNEIO_00366 1.1e-158 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MDEDNEIO_00367 2.7e-123 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDEDNEIO_00368 2e-57 D nuclear chromosome segregation
MDEDNEIO_00369 3e-267 pepC 3.4.22.40 E Peptidase C1-like family
MDEDNEIO_00370 7.4e-211 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MDEDNEIO_00371 1.8e-234 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MDEDNEIO_00372 1.1e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDEDNEIO_00373 2.8e-230 EGP Sugar (and other) transporter
MDEDNEIO_00374 1.1e-203 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MDEDNEIO_00375 1.8e-139 KT Transcriptional regulatory protein, C terminal
MDEDNEIO_00376 6.8e-180 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
MDEDNEIO_00377 3.5e-153 pstC P probably responsible for the translocation of the substrate across the membrane
MDEDNEIO_00378 1.1e-168 pstA P Phosphate transport system permease
MDEDNEIO_00379 1.2e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDEDNEIO_00380 2.5e-90 lemA S LemA family
MDEDNEIO_00381 0.0 S Predicted membrane protein (DUF2207)
MDEDNEIO_00382 2.2e-12 S Predicted membrane protein (DUF2207)
MDEDNEIO_00383 5.8e-173 S Predicted membrane protein (DUF2207)
MDEDNEIO_00384 5.9e-19
MDEDNEIO_00385 5.2e-164 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
MDEDNEIO_00386 1.9e-200 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MDEDNEIO_00387 7.5e-15 K helix_turn _helix lactose operon repressor
MDEDNEIO_00388 4.6e-166 2.7.11.1 S Pfam:HipA_N
MDEDNEIO_00389 2.8e-45 K Helix-turn-helix XRE-family like proteins
MDEDNEIO_00390 4.7e-111 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDEDNEIO_00391 6.1e-35 CP_0960 S Belongs to the UPF0109 family
MDEDNEIO_00392 1.1e-59 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MDEDNEIO_00393 6.3e-140 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
MDEDNEIO_00394 4.3e-269 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
MDEDNEIO_00395 2.5e-211 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MDEDNEIO_00396 9.8e-112 ribE 2.5.1.9 H Lumazine binding domain
MDEDNEIO_00397 3.5e-235 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MDEDNEIO_00398 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MDEDNEIO_00399 3e-164 S Endonuclease/Exonuclease/phosphatase family
MDEDNEIO_00400 1.3e-262 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDEDNEIO_00401 2.3e-162 P Cation efflux family
MDEDNEIO_00402 7e-303 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDEDNEIO_00403 6.9e-137 guaA1 6.3.5.2 F Peptidase C26
MDEDNEIO_00404 0.0 yjjK S ABC transporter
MDEDNEIO_00405 5.6e-63 vapC S Toxic component of a toxin-antitoxin (TA) module. An RNase
MDEDNEIO_00406 8.6e-44 stbC S Plasmid stability protein
MDEDNEIO_00407 1.7e-91 ilvN 2.2.1.6 E ACT domain
MDEDNEIO_00408 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
MDEDNEIO_00409 2.9e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDEDNEIO_00410 7.6e-31 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MDEDNEIO_00411 1.4e-118 yceD S Uncharacterized ACR, COG1399
MDEDNEIO_00412 1.2e-115
MDEDNEIO_00413 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDEDNEIO_00414 2e-51 S Protein of unknown function (DUF3039)
MDEDNEIO_00415 1.7e-190 yghZ C Aldo/keto reductase family
MDEDNEIO_00416 6.3e-70 soxR K MerR, DNA binding
MDEDNEIO_00417 7.2e-115
MDEDNEIO_00418 2e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDEDNEIO_00419 8.4e-159
MDEDNEIO_00420 4.1e-144 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MDEDNEIO_00421 1.1e-130 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDEDNEIO_00423 5.9e-217 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
MDEDNEIO_00424 2.1e-241 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
MDEDNEIO_00425 2.8e-222 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
MDEDNEIO_00426 5.8e-167 S Auxin Efflux Carrier
MDEDNEIO_00429 0.0 pgi 5.3.1.9 G Belongs to the GPI family
MDEDNEIO_00430 3.1e-254 abcT3 P ATPases associated with a variety of cellular activities
MDEDNEIO_00431 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00432 1.1e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDEDNEIO_00433 5.1e-140 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MDEDNEIO_00434 6.3e-151 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDEDNEIO_00435 7.5e-208 K helix_turn _helix lactose operon repressor
MDEDNEIO_00436 2.1e-119 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MDEDNEIO_00437 6.8e-09 L Transposase
MDEDNEIO_00438 2e-155 G Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00439 1.7e-141 G Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00440 9.9e-244 msmE7 G Bacterial extracellular solute-binding protein
MDEDNEIO_00441 8.4e-229 nagC GK ROK family
MDEDNEIO_00442 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
MDEDNEIO_00443 9e-81 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDEDNEIO_00444 0.0 yjcE P Sodium/hydrogen exchanger family
MDEDNEIO_00445 1.7e-147 ypfH S Phospholipase/Carboxylesterase
MDEDNEIO_00446 1.6e-128
MDEDNEIO_00447 1e-37 S Membrane
MDEDNEIO_00448 3e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDEDNEIO_00449 0.0 G Alpha mannosidase, middle domain
MDEDNEIO_00450 6.1e-88 G Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00451 3.1e-108 G Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00452 2.4e-131 G Bacterial extracellular solute-binding protein
MDEDNEIO_00453 2.6e-186 celF 3.2.1.86 GT4 G Family 4 glycosyl hydrolase
MDEDNEIO_00454 2.9e-89 K DeoR C terminal sensor domain
MDEDNEIO_00455 7.9e-76 G pfkB family carbohydrate kinase
MDEDNEIO_00456 3.4e-111 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
MDEDNEIO_00457 8.7e-80
MDEDNEIO_00458 3.2e-174 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDEDNEIO_00459 1.7e-168 endOF2 3.2.1.14, 3.2.1.35, 3.2.1.52, 3.2.1.96 GH18,GH20 G Glycosyl hydrolase, family 20, catalytic domain
MDEDNEIO_00460 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
MDEDNEIO_00461 2e-16 K helix_turn _helix lactose operon repressor
MDEDNEIO_00462 4.1e-84 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MDEDNEIO_00463 1.6e-288 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
MDEDNEIO_00464 3e-202 EGP Major facilitator Superfamily
MDEDNEIO_00465 1.8e-173 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDEDNEIO_00466 2e-266 KLT Domain of unknown function (DUF4032)
MDEDNEIO_00467 1.8e-209 ugpC E Belongs to the ABC transporter superfamily
MDEDNEIO_00468 2.2e-218 2.4.1.166 GT2 M Glycosyltransferase like family 2
MDEDNEIO_00469 3.7e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDEDNEIO_00471 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDEDNEIO_00472 3.5e-79 nrdI F Probably involved in ribonucleotide reductase function
MDEDNEIO_00473 4.1e-43 nrdH O Glutaredoxin
MDEDNEIO_00474 1.7e-114 K Helix-turn-helix XRE-family like proteins
MDEDNEIO_00475 3.7e-125 S Protein of unknown function (DUF3990)
MDEDNEIO_00476 1.3e-108 kcsA U Ion channel
MDEDNEIO_00477 6.9e-25 3.2.1.21 GH3 G Fibronectin type III-like domain
MDEDNEIO_00478 0.0 KLT Protein tyrosine kinase
MDEDNEIO_00479 2.5e-138 O Thioredoxin
MDEDNEIO_00481 2.5e-214 S G5
MDEDNEIO_00482 5.9e-166 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDEDNEIO_00483 1.1e-175 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MDEDNEIO_00484 3.2e-107 S LytR cell envelope-related transcriptional attenuator
MDEDNEIO_00485 2.8e-276 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
MDEDNEIO_00486 2.2e-118 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
MDEDNEIO_00487 0.0
MDEDNEIO_00488 0.0 murJ KLT MviN-like protein
MDEDNEIO_00489 2.2e-185 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDEDNEIO_00490 1.8e-219 parB K Belongs to the ParB family
MDEDNEIO_00491 7.8e-177 parA D CobQ CobB MinD ParA nucleotide binding domain protein
MDEDNEIO_00492 4.2e-121 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MDEDNEIO_00493 3.3e-92 jag S Putative single-stranded nucleic acids-binding domain
MDEDNEIO_00494 5.8e-175 yidC U Membrane protein insertase, YidC Oxa1 family
MDEDNEIO_00495 4e-33 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDEDNEIO_00496 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MDEDNEIO_00497 4.6e-285 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDEDNEIO_00498 2.9e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDEDNEIO_00499 6.4e-224 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDEDNEIO_00500 3e-81 S Protein of unknown function (DUF721)
MDEDNEIO_00501 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDEDNEIO_00502 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDEDNEIO_00503 2.1e-81 S Transmembrane domain of unknown function (DUF3566)
MDEDNEIO_00504 2.2e-273 S ATPase domain predominantly from Archaea
MDEDNEIO_00505 1e-14 K helix_turn _helix lactose operon repressor
MDEDNEIO_00506 1.8e-251 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MDEDNEIO_00507 5e-270 pip S YhgE Pip domain protein
MDEDNEIO_00508 0.0 pip S YhgE Pip domain protein
MDEDNEIO_00509 6e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
MDEDNEIO_00510 7.5e-59 S Protein of unknown function (DUF4235)
MDEDNEIO_00511 4.2e-135 G Phosphoglycerate mutase family
MDEDNEIO_00512 1.3e-246 amyE G Bacterial extracellular solute-binding protein
MDEDNEIO_00513 4.2e-181 K Psort location Cytoplasmic, score
MDEDNEIO_00514 9.7e-147 msmF G Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00515 4.4e-152 rafG G ABC transporter permease
MDEDNEIO_00516 1.9e-102 S Protein of unknown function, DUF624
MDEDNEIO_00517 6.7e-255 aroP E aromatic amino acid transport protein AroP K03293
MDEDNEIO_00518 5.2e-122 V ABC transporter
MDEDNEIO_00519 0.0 V FtsX-like permease family
MDEDNEIO_00520 1.2e-267 cycA E Amino acid permease
MDEDNEIO_00521 2.3e-77 ydgJ K helix_turn_helix multiple antibiotic resistance protein
MDEDNEIO_00522 0.0 lmrA1 V ABC transporter, ATP-binding protein
MDEDNEIO_00523 0.0 lmrA2 V ABC transporter transmembrane region
MDEDNEIO_00524 2e-159 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MDEDNEIO_00526 2.9e-182 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDEDNEIO_00527 4.7e-114
MDEDNEIO_00528 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDEDNEIO_00529 2.2e-45
MDEDNEIO_00530 6e-171 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MDEDNEIO_00531 7.7e-41 pepC 3.4.22.40 E Peptidase C1-like family
MDEDNEIO_00532 5.6e-204 pepC 3.4.22.40 E Peptidase C1-like family
MDEDNEIO_00533 2.3e-176 appB EP Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00534 9.2e-173 dppC EP N-terminal TM domain of oligopeptide transport permease C
MDEDNEIO_00535 0.0 oppD P Belongs to the ABC transporter superfamily
MDEDNEIO_00536 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
MDEDNEIO_00538 6e-250 EGP Major Facilitator Superfamily
MDEDNEIO_00539 3.2e-261 S AAA domain
MDEDNEIO_00540 2.6e-34 G domain, Protein
MDEDNEIO_00541 2.5e-250 S Domain of unknown function (DUF4143)
MDEDNEIO_00542 1.1e-269 S ATPase domain predominantly from Archaea
MDEDNEIO_00543 0.0 mdlA2 V ABC transporter
MDEDNEIO_00544 2.5e-311 yknV V ABC transporter
MDEDNEIO_00545 2.2e-196 S Fic/DOC family
MDEDNEIO_00546 1.3e-106 XK27_00240 K Fic/DOC family
MDEDNEIO_00547 9.3e-28 K helix_turn_helix, arabinose operon control protein
MDEDNEIO_00548 3.4e-89 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MDEDNEIO_00549 1.6e-63 2.7.1.2 GK ROK family
MDEDNEIO_00550 1.8e-113 xylE U Sugar (and other) transporter
MDEDNEIO_00551 3.8e-154 lipA I Hydrolase, alpha beta domain protein
MDEDNEIO_00553 2e-185 tatD L TatD related DNase
MDEDNEIO_00554 0.0 kup P Transport of potassium into the cell
MDEDNEIO_00555 1.3e-159 S Glutamine amidotransferase domain
MDEDNEIO_00556 1.5e-132 T HD domain
MDEDNEIO_00558 2.1e-181 V ABC transporter
MDEDNEIO_00559 2.4e-217 V ABC transporter permease
MDEDNEIO_00560 0.0 pflA S Protein of unknown function (DUF4012)
MDEDNEIO_00561 2.6e-201 I transferase activity, transferring acyl groups other than amino-acyl groups
MDEDNEIO_00562 1.1e-200 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MDEDNEIO_00563 1.2e-245 2.4.1.288 GT2 S Glycosyltransferase like family 2
MDEDNEIO_00564 3.2e-183 S Polysaccharide pyruvyl transferase
MDEDNEIO_00565 0.0 2.4.1.288 GT2 S Glycosyltransferase like family 2
MDEDNEIO_00566 6e-141 rgpC U Transport permease protein
MDEDNEIO_00567 9.2e-226 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
MDEDNEIO_00568 0.0 glfT 2.4.1.288 GT2 S Glycosyltransferase like family 2
MDEDNEIO_00569 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDEDNEIO_00570 1e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDEDNEIO_00571 1.8e-111 nusG K Participates in transcription elongation, termination and antitermination
MDEDNEIO_00572 2.8e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDEDNEIO_00574 1e-229 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
MDEDNEIO_00575 2.4e-198 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDEDNEIO_00576 1.5e-303 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDEDNEIO_00577 8.8e-40 rpmA J Ribosomal L27 protein
MDEDNEIO_00578 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
MDEDNEIO_00579 0.0 rne 3.1.26.12 J Ribonuclease E/G family
MDEDNEIO_00580 3e-229 dapE 3.5.1.18 E Peptidase dimerisation domain
MDEDNEIO_00581 6.1e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
MDEDNEIO_00582 9.4e-77 fucU 5.1.3.29 G RbsD / FucU transport protein family
MDEDNEIO_00583 4.6e-148 S Amidohydrolase
MDEDNEIO_00584 2.9e-203 fucP G Major Facilitator Superfamily
MDEDNEIO_00585 5.6e-141 IQ KR domain
MDEDNEIO_00586 1.4e-245 4.2.1.68 M Enolase C-terminal domain-like
MDEDNEIO_00587 1.5e-181 K Bacterial regulatory proteins, lacI family
MDEDNEIO_00588 4.5e-253 V Efflux ABC transporter, permease protein
MDEDNEIO_00589 1.2e-137 V ATPases associated with a variety of cellular activities
MDEDNEIO_00591 9.7e-17 S Protein of unknown function (DUF1778)
MDEDNEIO_00592 3e-08 K Acetyltransferase (GNAT) family
MDEDNEIO_00593 2.1e-279 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
MDEDNEIO_00594 1.1e-206 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MDEDNEIO_00595 1.4e-232 hom 1.1.1.3 E Homoserine dehydrogenase
MDEDNEIO_00596 3.2e-292 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MDEDNEIO_00597 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MDEDNEIO_00598 5.7e-109 K helix_turn _helix lactose operon repressor
MDEDNEIO_00599 2.4e-160 G Bacterial extracellular solute-binding protein
MDEDNEIO_00600 1.3e-134 malC P Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00601 3.1e-122 P Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00602 0.0 3.2.1.25 G beta-mannosidase
MDEDNEIO_00603 3.3e-192 bglA 3.2.1.21 G Glycosyl hydrolase family 1
MDEDNEIO_00604 7.3e-121 K Bacterial regulatory proteins, tetR family
MDEDNEIO_00605 7.8e-142 G Transmembrane secretion effector
MDEDNEIO_00606 1.4e-170 K LysR substrate binding domain protein
MDEDNEIO_00607 2.3e-245 patB 4.4.1.8 E Aminotransferase, class I II
MDEDNEIO_00608 4.1e-253 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDEDNEIO_00609 9.3e-253 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
MDEDNEIO_00610 1e-204 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
MDEDNEIO_00611 1.3e-130 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MDEDNEIO_00612 1.4e-267 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MDEDNEIO_00613 1.6e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
MDEDNEIO_00614 3.7e-243 S Calcineurin-like phosphoesterase
MDEDNEIO_00615 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MDEDNEIO_00616 3.5e-211 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
MDEDNEIO_00617 8.8e-129
MDEDNEIO_00618 3.4e-259 lacS G Psort location CytoplasmicMembrane, score 10.00
MDEDNEIO_00619 1.5e-270 lacS G Psort location CytoplasmicMembrane, score 10.00
MDEDNEIO_00620 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MDEDNEIO_00621 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
MDEDNEIO_00622 5.1e-257 fucA 3.2.1.51 GH29 G Alpha-L-fucosidase
MDEDNEIO_00623 9.3e-69 fucU 5.1.3.29 G RbsD / FucU transport protein family
MDEDNEIO_00624 6.2e-152 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
MDEDNEIO_00625 3.9e-142 IQ KR domain
MDEDNEIO_00626 4.1e-242 4.2.1.68 M Enolase C-terminal domain-like
MDEDNEIO_00627 1.3e-95 S Protein of unknown function, DUF624
MDEDNEIO_00628 3.9e-152 G Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00629 1.6e-150 G Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00630 8.5e-221 G Bacterial extracellular solute-binding protein
MDEDNEIO_00631 1.6e-123 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
MDEDNEIO_00632 1.3e-136 nanL 4.3.3.7 EM Dihydrodipicolinate synthetase family
MDEDNEIO_00633 1.5e-246 G Bacterial extracellular solute-binding protein
MDEDNEIO_00634 0.0 4.2.1.53 S MCRA family
MDEDNEIO_00635 8.9e-75 yneG S Domain of unknown function (DUF4186)
MDEDNEIO_00636 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
MDEDNEIO_00637 3.2e-129 S Virulence factor BrkB
MDEDNEIO_00638 5.8e-103
MDEDNEIO_00639 1.9e-54 V ATPases associated with a variety of cellular activities
MDEDNEIO_00640 1.3e-179 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MDEDNEIO_00641 3.5e-89 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDEDNEIO_00642 4.1e-38 tccB2 V DivIVA protein
MDEDNEIO_00643 3.9e-42 yggT S YGGT family
MDEDNEIO_00644 7.5e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDEDNEIO_00645 3e-194 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDEDNEIO_00646 9.2e-239 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDEDNEIO_00647 2.8e-295 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
MDEDNEIO_00648 1.3e-165 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MDEDNEIO_00649 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MDEDNEIO_00650 1.5e-230 O AAA domain (Cdc48 subfamily)
MDEDNEIO_00651 3e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MDEDNEIO_00652 1.6e-61 S Thiamine-binding protein
MDEDNEIO_00653 9.7e-63 2.7.13.3 T Histidine kinase
MDEDNEIO_00654 1.3e-247 O SERine Proteinase INhibitors
MDEDNEIO_00655 4.3e-189 K helix_turn _helix lactose operon repressor
MDEDNEIO_00656 1.4e-240 lacY P LacY proton/sugar symporter
MDEDNEIO_00657 3e-303 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MDEDNEIO_00658 1.5e-138 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00659 4.1e-203 P NMT1/THI5 like
MDEDNEIO_00660 9.6e-209 iunH1 3.2.2.1 F nucleoside hydrolase
MDEDNEIO_00661 5.8e-154 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDEDNEIO_00662 1.3e-112 recO L Involved in DNA repair and RecF pathway recombination
MDEDNEIO_00663 4e-285 I acetylesterase activity
MDEDNEIO_00664 4.1e-231 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MDEDNEIO_00665 1.8e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MDEDNEIO_00666 1e-227 2.7.11.1 NU Tfp pilus assembly protein FimV
MDEDNEIO_00668 2e-44 S Protein of unknown function (DUF3052)
MDEDNEIO_00669 4.3e-158 lon T Belongs to the peptidase S16 family
MDEDNEIO_00670 0.0 S Zincin-like metallopeptidase
MDEDNEIO_00671 2.6e-286 uvrD2 3.6.4.12 L DNA helicase
MDEDNEIO_00672 2.9e-288 mphA S Aminoglycoside phosphotransferase
MDEDNEIO_00673 1.2e-32 S Protein of unknown function (DUF3107)
MDEDNEIO_00674 1.6e-168 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
MDEDNEIO_00675 4.8e-126 S Vitamin K epoxide reductase
MDEDNEIO_00676 2e-163 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MDEDNEIO_00677 7.2e-144 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MDEDNEIO_00678 4.8e-154 S Patatin-like phospholipase
MDEDNEIO_00679 1.1e-21 S Amidohydrolase
MDEDNEIO_00681 1.7e-63 V ABC transporter
MDEDNEIO_00682 4.6e-90 L Transposase and inactivated derivatives IS30 family
MDEDNEIO_00683 4.6e-110 XK27_08050 O prohibitin homologues
MDEDNEIO_00684 4.3e-110 E Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00685 4.8e-135 tcyA ET Bacterial periplasmic substrate-binding proteins
MDEDNEIO_00686 2.8e-137 3.6.3.21 E ATPases associated with a variety of cellular activities
MDEDNEIO_00687 1.4e-34 XAC3035 O Glutaredoxin
MDEDNEIO_00688 1.1e-239 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
MDEDNEIO_00689 4.2e-228 S Peptidase dimerisation domain
MDEDNEIO_00690 0.0 E ATPases associated with a variety of cellular activities
MDEDNEIO_00691 0.0 E Branched-chain amino acid transport system / permease component
MDEDNEIO_00692 7.6e-219 E Receptor family ligand binding region
MDEDNEIO_00693 1.9e-200 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
MDEDNEIO_00694 5e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDEDNEIO_00695 3.1e-155 E Glyoxalase-like domain
MDEDNEIO_00696 2.5e-42 XAC3035 O Glutaredoxin
MDEDNEIO_00697 4.9e-224 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MDEDNEIO_00698 1.5e-126 cjaA ET Bacterial periplasmic substrate-binding proteins
MDEDNEIO_00699 4.1e-115 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
MDEDNEIO_00700 6.8e-111 glnP E Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00701 5.4e-97 papP E Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00702 1.2e-120 ypfH S Phospholipase/Carboxylesterase
MDEDNEIO_00703 0.0 tetP J Elongation factor G, domain IV
MDEDNEIO_00704 1.2e-129 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
MDEDNEIO_00706 5.9e-103 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MDEDNEIO_00707 6.3e-168 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MDEDNEIO_00708 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MDEDNEIO_00709 5.1e-238 carA 6.3.5.5 F Belongs to the CarA family
MDEDNEIO_00710 1.6e-76 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDEDNEIO_00711 4e-104 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDEDNEIO_00712 1.4e-112 ybbL V ATPases associated with a variety of cellular activities
MDEDNEIO_00713 2.7e-74 ybbM V Uncharacterised protein family (UPF0014)
MDEDNEIO_00714 0.0 G Glycosyl hydrolase family 20, domain 2
MDEDNEIO_00715 3.6e-202 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MDEDNEIO_00716 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDEDNEIO_00717 0.0 S Tetratricopeptide repeat
MDEDNEIO_00718 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MDEDNEIO_00719 3.2e-139 bioM P ATPases associated with a variety of cellular activities
MDEDNEIO_00720 1.7e-227 E Aminotransferase class I and II
MDEDNEIO_00721 3.6e-140 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
MDEDNEIO_00722 3.1e-200 S Glycosyltransferase, group 2 family protein
MDEDNEIO_00723 1.9e-102 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDEDNEIO_00724 0.0 ecfA GP ABC transporter, ATP-binding protein
MDEDNEIO_00725 2.7e-46 yhbY J CRS1_YhbY
MDEDNEIO_00726 5.4e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MDEDNEIO_00727 5.5e-58 J TM2 domain
MDEDNEIO_00728 8.8e-184 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MDEDNEIO_00729 1.5e-248 EGP Major facilitator Superfamily
MDEDNEIO_00730 3e-246 rarA L Recombination factor protein RarA
MDEDNEIO_00731 0.0 L DEAD DEAH box helicase
MDEDNEIO_00732 1.2e-178 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
MDEDNEIO_00733 1.2e-283 phoN I PAP2 superfamily
MDEDNEIO_00734 8.9e-185 gluD E Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00735 4.3e-105 gluC E Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00736 4.4e-152 gluB ET Belongs to the bacterial solute-binding protein 3 family
MDEDNEIO_00737 8.5e-141 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
MDEDNEIO_00738 7.9e-182 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
MDEDNEIO_00739 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MDEDNEIO_00740 9.6e-261 hisS 6.1.1.21 J Histidyl-tRNA synthetase
MDEDNEIO_00741 4.3e-211 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
MDEDNEIO_00742 1.4e-304 3.1.3.5 F 5'-nucleotidase, C-terminal domain
MDEDNEIO_00743 0.0 clpC O ATPase family associated with various cellular activities (AAA)
MDEDNEIO_00744 1.8e-173 uspA T Belongs to the universal stress protein A family
MDEDNEIO_00745 1.3e-162 S Protein of unknown function (DUF3027)
MDEDNEIO_00746 6.5e-66 cspB K 'Cold-shock' DNA-binding domain
MDEDNEIO_00747 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MDEDNEIO_00748 6.8e-133 KT Response regulator receiver domain protein
MDEDNEIO_00749 1.6e-64
MDEDNEIO_00750 1.7e-34 S Proteins of 100 residues with WXG
MDEDNEIO_00751 4.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDEDNEIO_00752 1.4e-37 K 'Cold-shock' DNA-binding domain
MDEDNEIO_00753 1.2e-70 S LytR cell envelope-related transcriptional attenuator
MDEDNEIO_00754 2.1e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDEDNEIO_00755 9.6e-192 moxR S ATPase family associated with various cellular activities (AAA)
MDEDNEIO_00756 3.7e-171 S Protein of unknown function DUF58
MDEDNEIO_00757 8.4e-91
MDEDNEIO_00758 8e-183 S von Willebrand factor (vWF) type A domain
MDEDNEIO_00759 5.8e-162 S von Willebrand factor (vWF) type A domain
MDEDNEIO_00760 1.3e-44
MDEDNEIO_00761 3.9e-46
MDEDNEIO_00762 1.3e-290 S PGAP1-like protein
MDEDNEIO_00763 8.1e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
MDEDNEIO_00764 0.0 S Lysylphosphatidylglycerol synthase TM region
MDEDNEIO_00765 6.2e-42 hup L Belongs to the bacterial histone-like protein family
MDEDNEIO_00766 1.4e-11 L HTH-like domain
MDEDNEIO_00767 2.5e-31 L HTH-like domain
MDEDNEIO_00768 6.1e-24
MDEDNEIO_00770 1.5e-58
MDEDNEIO_00771 2.6e-33
MDEDNEIO_00773 9.6e-42 S Protein of unknown function (DUF2442)
MDEDNEIO_00774 3.4e-18 S Domain of unknown function (DUF4160)
MDEDNEIO_00775 7.9e-12 K Helix-turn-helix domain
MDEDNEIO_00776 2e-40 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MDEDNEIO_00777 7.5e-178 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MDEDNEIO_00778 2.6e-113 cas4 3.1.12.1 L Domain of unknown function DUF83
MDEDNEIO_00779 1.5e-109 L IstB-like ATP binding protein
MDEDNEIO_00780 4.4e-13 L IstB-like ATP binding protein
MDEDNEIO_00781 2.6e-253 L PFAM Integrase catalytic
MDEDNEIO_00782 2.4e-37 K Bacterial regulatory proteins, tetR family
MDEDNEIO_00783 1e-89 3.2.1.21 G Glycosyl hydrolase family 1
MDEDNEIO_00784 8.8e-55 E Belongs to the ABC transporter superfamily
MDEDNEIO_00785 9.2e-58 oppD EP Belongs to the ABC transporter superfamily
MDEDNEIO_00786 3.2e-46 MA20_17240 EP Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00787 1.6e-57 MA20_17245 EP Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00788 6.3e-88 MA20_17250 E Bacterial extracellular solute-binding proteins, family 5 Middle
MDEDNEIO_00789 2.1e-140 L PFAM Integrase catalytic
MDEDNEIO_00790 3.4e-288 L PFAM Integrase catalytic
MDEDNEIO_00791 1.8e-136 L IstB-like ATP binding protein
MDEDNEIO_00792 2.7e-53 L PFAM Integrase catalytic
MDEDNEIO_00793 1.1e-104 L PFAM Integrase catalytic
MDEDNEIO_00794 4.7e-156 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MDEDNEIO_00795 5.1e-74 casE S CRISPR_assoc
MDEDNEIO_00796 6.2e-87 casD S CRISPR-associated protein (Cas_Cas5)
MDEDNEIO_00797 3.4e-150 casC L CT1975-like protein
MDEDNEIO_00798 8.1e-56 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
MDEDNEIO_00799 2.5e-202 cas3 L CRISPR-associated protein Cse1 (CRISPR_cse1)
MDEDNEIO_00800 0.0 cas3 L DEAD-like helicases superfamily
MDEDNEIO_00801 1.3e-144 S Fic/DOC family
MDEDNEIO_00802 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDEDNEIO_00803 2.3e-242 malY 4.4.1.8 E Aminotransferase, class I II
MDEDNEIO_00804 1e-160 nanL 4.3.3.7 EM Dihydrodipicolinate synthetase family
MDEDNEIO_00805 8.5e-143 oppF E ATPases associated with a variety of cellular activities
MDEDNEIO_00806 0.0 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
MDEDNEIO_00807 5.5e-167 oppB6 EP Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00808 1.2e-270 E Bacterial extracellular solute-binding proteins, family 5 Middle
MDEDNEIO_00809 0.0 nanI 3.2.1.18 GH33 G BNR repeat-like domain
MDEDNEIO_00810 1.6e-115 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MDEDNEIO_00811 2.9e-120 2.7.1.2 GK ROK family
MDEDNEIO_00812 9.1e-143 L Domain of unknown function (DUF4862)
MDEDNEIO_00813 3.8e-107 K FCD
MDEDNEIO_00814 2.9e-174 lacR K Transcriptional regulator, LacI family
MDEDNEIO_00815 2.2e-147 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDEDNEIO_00816 2.8e-162 dcuD C C4-dicarboxylate anaerobic carrier
MDEDNEIO_00817 1.7e-104 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MDEDNEIO_00818 5.4e-43 K acetyltransferase
MDEDNEIO_00819 7.9e-127 rbsR K helix_turn _helix lactose operon repressor
MDEDNEIO_00820 0.0 V ABC transporter transmembrane region
MDEDNEIO_00821 0.0 V ABC transporter, ATP-binding protein
MDEDNEIO_00822 2.3e-82 K MarR family
MDEDNEIO_00823 0.0 yliE T Putative diguanylate phosphodiesterase
MDEDNEIO_00824 1.9e-110 S Domain of unknown function (DUF4956)
MDEDNEIO_00825 8.5e-156 P VTC domain
MDEDNEIO_00826 8.3e-305 cotH M CotH kinase protein
MDEDNEIO_00827 2.3e-68 pelG S Putative exopolysaccharide Exporter (EPS-E)
MDEDNEIO_00828 8e-191 pelG S Putative exopolysaccharide Exporter (EPS-E)
MDEDNEIO_00829 1.8e-278 pelF GT4 M Domain of unknown function (DUF3492)
MDEDNEIO_00830 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
MDEDNEIO_00831 1e-162
MDEDNEIO_00832 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
MDEDNEIO_00833 6.1e-19 bglK 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
MDEDNEIO_00834 9.2e-237 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
MDEDNEIO_00835 7.7e-70 S Nucleotidyltransferase substrate binding protein like
MDEDNEIO_00836 3.6e-45 S Nucleotidyltransferase domain
MDEDNEIO_00837 1.5e-64 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
MDEDNEIO_00838 6.5e-256 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
MDEDNEIO_00839 2.5e-186 L Helix-turn-helix domain
MDEDNEIO_00840 2.1e-100 L Resolvase, N terminal domain
MDEDNEIO_00841 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
MDEDNEIO_00842 1.1e-143 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDEDNEIO_00843 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
MDEDNEIO_00844 4.2e-253 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDEDNEIO_00845 1.2e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDEDNEIO_00846 4.2e-233 S peptidyl-serine autophosphorylation
MDEDNEIO_00847 1.2e-91 ywrO 1.6.5.2 S Flavodoxin-like fold
MDEDNEIO_00848 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MDEDNEIO_00849 1.3e-75 F Nucleoside 2-deoxyribosyltransferase
MDEDNEIO_00850 3.3e-33 K Acetyltransferase (GNAT) domain
MDEDNEIO_00852 3.6e-186 S Endonuclease/Exonuclease/phosphatase family
MDEDNEIO_00853 1.4e-36 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MDEDNEIO_00854 2.2e-232 aspB E Aminotransferase class-V
MDEDNEIO_00855 7.2e-200 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
MDEDNEIO_00856 6.4e-85 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MDEDNEIO_00857 7.2e-33 XK27_03610 K Acetyltransferase (GNAT) domain
MDEDNEIO_00858 7.4e-80 S PFAM Uncharacterised protein family UPF0150
MDEDNEIO_00859 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
MDEDNEIO_00860 2.2e-212 K WYL domain
MDEDNEIO_00861 3.2e-144 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MDEDNEIO_00862 5.1e-248 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
MDEDNEIO_00863 9.2e-152 map 3.4.11.18 E Methionine aminopeptidase
MDEDNEIO_00864 3.3e-98 S Short repeat of unknown function (DUF308)
MDEDNEIO_00865 0.0 pepO 3.4.24.71 O Peptidase family M13
MDEDNEIO_00866 1e-51 L Single-strand binding protein family
MDEDNEIO_00867 7.8e-225 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MDEDNEIO_00868 3.8e-125 U Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00869 1.7e-160 U Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00870 8.7e-215 P Bacterial extracellular solute-binding protein
MDEDNEIO_00871 2.7e-227 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MDEDNEIO_00872 2.1e-180 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MDEDNEIO_00873 5.8e-181 plsC2 2.3.1.51 I Phosphate acyltransferases
MDEDNEIO_00874 1e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
MDEDNEIO_00875 1.5e-145 L Uncharacterized conserved protein (DUF2075)
MDEDNEIO_00876 4.9e-12 J tRNA 5'-leader removal
MDEDNEIO_00878 2.6e-117 cyaA 4.6.1.1 S CYTH
MDEDNEIO_00879 3.7e-166 trxA2 O Tetratricopeptide repeat
MDEDNEIO_00880 1.2e-180
MDEDNEIO_00881 6.6e-185
MDEDNEIO_00882 9.2e-157 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
MDEDNEIO_00883 5e-134 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MDEDNEIO_00884 1.6e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MDEDNEIO_00885 1.5e-280 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDEDNEIO_00886 4.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDEDNEIO_00887 5e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDEDNEIO_00888 5.2e-145 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDEDNEIO_00889 7.9e-59 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDEDNEIO_00890 1.5e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDEDNEIO_00891 1e-145 atpB C it plays a direct role in the translocation of protons across the membrane
MDEDNEIO_00892 2.3e-203 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MDEDNEIO_00893 2.3e-20 S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
MDEDNEIO_00894 6.1e-13
MDEDNEIO_00897 7.2e-83
MDEDNEIO_00898 1.1e-09
MDEDNEIO_00899 1.1e-20
MDEDNEIO_00900 5.9e-104 D ftsk spoiiie
MDEDNEIO_00901 8.7e-81 S Plasmid replication protein
MDEDNEIO_00902 9.1e-17
MDEDNEIO_00903 4.6e-30 hsdBM 2.1.1.72 L Eco57I restriction-modification methylase
MDEDNEIO_00904 1.7e-95 K Psort location Cytoplasmic, score 8.87
MDEDNEIO_00905 1.7e-76 E Glyoxalase-like domain
MDEDNEIO_00906 1.2e-139 pstIR 2.1.1.72, 3.1.21.4 L BsuBI/PstI restriction endonuclease C-terminus
MDEDNEIO_00907 1.2e-201 L Phage integrase family
MDEDNEIO_00908 7.3e-19 G Hypothetical glycosyl hydrolase 6
MDEDNEIO_00909 3.8e-12 G Hypothetical glycosyl hydrolase 6
MDEDNEIO_00910 2.2e-16 S Maff2 family
MDEDNEIO_00911 1.9e-07 L Transposase DDE domain
MDEDNEIO_00912 1.4e-74 S Psort location Cytoplasmic, score 8.87
MDEDNEIO_00913 0.0 K RNA polymerase II activating transcription factor binding
MDEDNEIO_00914 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MDEDNEIO_00915 6.3e-90 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MDEDNEIO_00916 1.6e-97 mntP P Probably functions as a manganese efflux pump
MDEDNEIO_00917 1.3e-80
MDEDNEIO_00918 8.3e-132 KT Transcriptional regulatory protein, C terminal
MDEDNEIO_00919 5.6e-129 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDEDNEIO_00920 2e-280 E Bacterial extracellular solute-binding proteins, family 5 Middle
MDEDNEIO_00921 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDEDNEIO_00922 8.4e-298 S domain protein
MDEDNEIO_00923 2e-62 tyrA 5.4.99.5 E Chorismate mutase type II
MDEDNEIO_00925 1.1e-236 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MDEDNEIO_00926 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
MDEDNEIO_00927 7e-283 S Histidine phosphatase superfamily (branch 2)
MDEDNEIO_00928 3.3e-52 S Protein of unknown function (DUF2469)
MDEDNEIO_00929 5.2e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
MDEDNEIO_00930 7.9e-285 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDEDNEIO_00931 7.1e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDEDNEIO_00932 7.7e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDEDNEIO_00933 3.5e-185 K Psort location Cytoplasmic, score
MDEDNEIO_00934 1.4e-158 spoU 2.1.1.185 J RNA methyltransferase TrmH family
MDEDNEIO_00935 4.7e-98 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDEDNEIO_00936 2.5e-187 rmuC S RmuC family
MDEDNEIO_00937 1.6e-42 csoR S Metal-sensitive transcriptional repressor
MDEDNEIO_00938 0.0 pacS 1.9.3.1, 3.6.3.54 P E1-E2 ATPase
MDEDNEIO_00939 3.1e-125 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MDEDNEIO_00941 2.6e-198 ykiI
MDEDNEIO_00942 2.2e-246 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MDEDNEIO_00943 1.2e-227 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDEDNEIO_00944 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MDEDNEIO_00947 5.9e-126 3.1.3.85 G Phosphoglycerate mutase family
MDEDNEIO_00948 3.4e-62 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDEDNEIO_00949 2.9e-257 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDEDNEIO_00951 2.4e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDEDNEIO_00952 1.9e-264 XK27_09800 I Psort location CytoplasmicMembrane, score 9.99
MDEDNEIO_00953 7.4e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MDEDNEIO_00954 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MDEDNEIO_00955 5.1e-155 metQ P NLPA lipoprotein
MDEDNEIO_00956 6.2e-42 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDEDNEIO_00957 3.3e-164 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDEDNEIO_00958 1.3e-112 metI P Binding-protein-dependent transport system inner membrane component
MDEDNEIO_00959 1e-223 S Peptidase dimerisation domain
MDEDNEIO_00960 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MDEDNEIO_00961 8.5e-34
MDEDNEIO_00962 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MDEDNEIO_00963 7.4e-174 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDEDNEIO_00964 9.9e-120 S Protein of unknown function (DUF3000)
MDEDNEIO_00965 4.9e-251 rnd 3.1.13.5 J 3'-5' exonuclease
MDEDNEIO_00966 4.9e-233 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDEDNEIO_00967 1.4e-230 clcA_2 P Voltage gated chloride channel
MDEDNEIO_00968 2.1e-53
MDEDNEIO_00969 1.4e-115 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDEDNEIO_00970 2.1e-123 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDEDNEIO_00971 2e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDEDNEIO_00976 5.2e-230 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MDEDNEIO_00977 2.4e-146 fmt2 3.2.2.10 S Belongs to the LOG family
MDEDNEIO_00978 4.3e-110 safC S O-methyltransferase
MDEDNEIO_00979 2.4e-178 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
MDEDNEIO_00980 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
MDEDNEIO_00981 2e-305 dprA 5.99.1.2 LU DNA recombination-mediator protein A
MDEDNEIO_00982 1.2e-291 comM O Magnesium chelatase, subunit ChlI C-terminal
MDEDNEIO_00983 9.6e-94 yraN L Belongs to the UPF0102 family
MDEDNEIO_00984 1.4e-164 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MDEDNEIO_00985 1.8e-248 metY 2.5.1.49 E Aminotransferase class-V
MDEDNEIO_00986 2e-145 V ABC transporter, ATP-binding protein
MDEDNEIO_00987 0.0 MV MacB-like periplasmic core domain
MDEDNEIO_00988 6e-136 K helix_turn_helix, Lux Regulon
MDEDNEIO_00989 0.0 tcsS2 T Histidine kinase
MDEDNEIO_00990 7.2e-283 pip 3.4.11.5 S alpha/beta hydrolase fold
MDEDNEIO_00991 1.2e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDEDNEIO_00992 1.2e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDEDNEIO_00993 1.4e-164 K Arac family
MDEDNEIO_00994 3.4e-26 S rRNA binding
MDEDNEIO_00995 1.4e-117 V MatE
MDEDNEIO_00996 1.5e-48
MDEDNEIO_00997 1.1e-94 V ATPases associated with a variety of cellular activities
MDEDNEIO_00998 6.5e-262 V FtsX-like permease family
MDEDNEIO_00999 1.5e-59 K Virulence activator alpha C-term
MDEDNEIO_01001 1.2e-292 EGP Major Facilitator Superfamily
MDEDNEIO_01003 1.6e-174 glkA 2.7.1.2 G ROK family
MDEDNEIO_01004 7.6e-71 EGP Major facilitator superfamily
MDEDNEIO_01005 1.2e-165 dkgB S Oxidoreductase, aldo keto reductase family protein
MDEDNEIO_01006 1.1e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MDEDNEIO_01007 2.9e-153
MDEDNEIO_01008 1.3e-28 EGP Major facilitator Superfamily
MDEDNEIO_01009 8.3e-32 EGP Major Facilitator Superfamily
MDEDNEIO_01010 2.2e-270 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MDEDNEIO_01011 9.2e-236 bdhA C Iron-containing alcohol dehydrogenase
MDEDNEIO_01012 9.2e-192 K Bacterial regulatory proteins, lacI family
MDEDNEIO_01013 8.9e-208 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
MDEDNEIO_01014 4e-60 MA20_14025 U Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01015 1.5e-68 malC U Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01016 1.3e-138 MA20_14020 P Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01017 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MDEDNEIO_01018 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
MDEDNEIO_01019 1.7e-108 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
MDEDNEIO_01020 0.0 G Psort location Cytoplasmic, score 8.87
MDEDNEIO_01022 3.1e-206 G Periplasmic binding protein domain
MDEDNEIO_01023 2.8e-293 araG 3.6.3.17 G ATPases associated with a variety of cellular activities
MDEDNEIO_01024 3.9e-210 gguB U Branched-chain amino acid transport system / permease component
MDEDNEIO_01025 8.7e-38
MDEDNEIO_01026 2e-30
MDEDNEIO_01027 6.1e-285 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
MDEDNEIO_01028 5.5e-228 xylR GK ROK family
MDEDNEIO_01030 1.3e-36 rpmE J Binds the 23S rRNA
MDEDNEIO_01031 5.3e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDEDNEIO_01032 6.1e-144 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDEDNEIO_01033 1.6e-200 livK E Receptor family ligand binding region
MDEDNEIO_01034 1.2e-105 U Belongs to the binding-protein-dependent transport system permease family
MDEDNEIO_01035 1.1e-171 livM U Belongs to the binding-protein-dependent transport system permease family
MDEDNEIO_01036 3.1e-153 E Branched-chain amino acid ATP-binding cassette transporter
MDEDNEIO_01037 1.5e-121 livF E ATPases associated with a variety of cellular activities
MDEDNEIO_01038 1.5e-118 ywlC 2.7.7.87 J Belongs to the SUA5 family
MDEDNEIO_01039 1.1e-202 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
MDEDNEIO_01040 1.1e-289 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MDEDNEIO_01041 1.2e-115 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MDEDNEIO_01042 6.3e-268 recD2 3.6.4.12 L PIF1-like helicase
MDEDNEIO_01043 9e-29 GT87 NU Tfp pilus assembly protein FimV
MDEDNEIO_01044 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDEDNEIO_01045 4.2e-155 yvgN 1.1.1.346 S Aldo/keto reductase family
MDEDNEIO_01046 2.8e-238 2.7.1.17 GH19 G FGGY family of carbohydrate kinases, N-terminal domain
MDEDNEIO_01047 1.6e-255 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MDEDNEIO_01048 1.8e-220 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MDEDNEIO_01049 6e-111 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
MDEDNEIO_01050 5e-97
MDEDNEIO_01051 2e-120 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MDEDNEIO_01052 6.3e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
MDEDNEIO_01053 1.5e-20 S Uncharacterized protein conserved in bacteria (DUF2252)
MDEDNEIO_01054 2.6e-263 glnA2 6.3.1.2 E glutamine synthetase
MDEDNEIO_01055 1.4e-186 EGP Major facilitator Superfamily
MDEDNEIO_01056 2.8e-131 appC EP Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01057 2.1e-177 EP Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01058 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
MDEDNEIO_01059 5.1e-309 P Belongs to the ABC transporter superfamily
MDEDNEIO_01060 1.4e-168 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MDEDNEIO_01061 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
MDEDNEIO_01062 4.4e-123 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
MDEDNEIO_01063 1.4e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDEDNEIO_01064 1.6e-174 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
MDEDNEIO_01065 6.7e-157 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDEDNEIO_01066 4.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDEDNEIO_01067 1.3e-35 M Lysin motif
MDEDNEIO_01068 3.8e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDEDNEIO_01069 2.7e-227 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MDEDNEIO_01070 0.0 L DNA helicase
MDEDNEIO_01071 5.5e-92 mraZ K Belongs to the MraZ family
MDEDNEIO_01072 6.4e-196 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDEDNEIO_01073 3.7e-73 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MDEDNEIO_01074 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
MDEDNEIO_01075 5.4e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDEDNEIO_01076 2.4e-246 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDEDNEIO_01077 9.5e-203 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDEDNEIO_01078 1.1e-272 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDEDNEIO_01079 1.8e-223 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
MDEDNEIO_01080 5.7e-222 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDEDNEIO_01081 1.6e-285 murC 6.3.2.8 M Belongs to the MurCDEF family
MDEDNEIO_01082 2.3e-182 ftsQ 6.3.2.4 D Cell division protein FtsQ
MDEDNEIO_01083 4.1e-15
MDEDNEIO_01084 3.2e-50 L Transposase
MDEDNEIO_01085 5e-109 V ATPases associated with a variety of cellular activities
MDEDNEIO_01086 4.6e-81 V ABC-2 family transporter protein
MDEDNEIO_01087 6.2e-23 msmE G transport
MDEDNEIO_01088 1.9e-146 U Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01089 1.2e-150 U Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01090 2.4e-153 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MDEDNEIO_01091 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
MDEDNEIO_01092 1.1e-295 pccB I Carboxyl transferase domain
MDEDNEIO_01093 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MDEDNEIO_01094 2.2e-13 bioY S BioY family
MDEDNEIO_01095 1.3e-141 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
MDEDNEIO_01096 0.0
MDEDNEIO_01097 5.4e-137 QT PucR C-terminal helix-turn-helix domain
MDEDNEIO_01098 2.1e-23 K helix_turn _helix lactose operon repressor
MDEDNEIO_01099 1.6e-116 2.2.1.1 G Transketolase, pyrimidine binding domain
MDEDNEIO_01100 3.2e-108 tktN 2.2.1.1 G Dehydrogenase E1 component
MDEDNEIO_01101 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
MDEDNEIO_01102 1.1e-129 EGP Major facilitator Superfamily
MDEDNEIO_01103 2.1e-08 ycnE S Antibiotic biosynthesis monooxygenase
MDEDNEIO_01104 1.9e-115 iolT EGP Major facilitator Superfamily
MDEDNEIO_01105 1.2e-128 iolE 4.2.1.44 G dehydratase
MDEDNEIO_01106 4e-139 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MDEDNEIO_01107 4.9e-105 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
MDEDNEIO_01108 2.5e-48 K helix_turn_helix, arabinose operon control protein
MDEDNEIO_01109 1.5e-157 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MDEDNEIO_01110 1.7e-83 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MDEDNEIO_01111 3e-75 K Sugar-specific transcriptional regulator TrmB
MDEDNEIO_01112 5.6e-69 K Bacterial transcriptional regulator
MDEDNEIO_01113 8.4e-207 1.2.1.16, 1.2.1.20, 1.2.1.79 C Aldehyde dehydrogenase family
MDEDNEIO_01114 2.4e-161 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
MDEDNEIO_01115 3.2e-129 iolB 5.3.1.30 G PFAM Myo-inositol catabolism IolB domain protein
MDEDNEIO_01116 1.9e-275 iolD 3.7.1.22 E Thiamine pyrophosphate enzyme, central domain
MDEDNEIO_01117 4.9e-175 L Transposase and inactivated derivatives IS30 family
MDEDNEIO_01118 1e-69
MDEDNEIO_01119 1.4e-20
MDEDNEIO_01121 6.1e-55 S Fic/DOC family
MDEDNEIO_01123 9.6e-12 2.7.11.1 S HipA-like C-terminal domain
MDEDNEIO_01124 5.9e-14 xerH L Phage integrase family
MDEDNEIO_01125 4.7e-16 xerH L Phage integrase family
MDEDNEIO_01128 1.8e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDEDNEIO_01129 9.9e-98 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
MDEDNEIO_01130 6.9e-150 yeaZ 2.3.1.234 O Glycoprotease family
MDEDNEIO_01131 5.3e-101 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
MDEDNEIO_01132 4.6e-177 holA 2.7.7.7 L DNA polymerase III delta subunit
MDEDNEIO_01133 2.1e-249 comE S Competence protein
MDEDNEIO_01134 7e-58 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
MDEDNEIO_01135 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDEDNEIO_01136 1.7e-149 ET Bacterial periplasmic substrate-binding proteins
MDEDNEIO_01137 3.1e-170 corA P CorA-like Mg2+ transporter protein
MDEDNEIO_01138 6.9e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MDEDNEIO_01139 1.8e-237 L ribosomal rna small subunit methyltransferase
MDEDNEIO_01140 2.7e-70 pdxH S Pfam:Pyridox_oxidase
MDEDNEIO_01141 5.4e-159 EG EamA-like transporter family
MDEDNEIO_01142 1.6e-87
MDEDNEIO_01143 4e-26 T PhoQ Sensor
MDEDNEIO_01144 2.8e-68 T PhoQ Sensor
MDEDNEIO_01145 2e-99 T Transcriptional regulatory protein, C terminal
MDEDNEIO_01146 3.3e-88
MDEDNEIO_01147 1.4e-56 spaG S Lantibiotic protection ABC transporter permease subunit, MutG family
MDEDNEIO_01148 9.9e-63 S ABC-2 family transporter protein
MDEDNEIO_01149 1.5e-91 mutF V ABC transporter ATP-binding
MDEDNEIO_01151 4.8e-173
MDEDNEIO_01152 2.8e-101 V ATPases associated with a variety of cellular activities
MDEDNEIO_01153 1.7e-52 L Helix-turn-helix domain
MDEDNEIO_01154 7.9e-78 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MDEDNEIO_01156 4.5e-23 D COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MDEDNEIO_01157 3e-33 S Bacterial protein of unknown function (DUF961)
MDEDNEIO_01158 1.9e-42 yxaM EGP Major Facilitator Superfamily
MDEDNEIO_01161 3.5e-15 V Abi-like protein
MDEDNEIO_01162 5.9e-185 V Abi-like protein
MDEDNEIO_01163 4.4e-263 L Phage integrase family
MDEDNEIO_01164 2.1e-140 fic D Fic/DOC family
MDEDNEIO_01165 3.3e-26
MDEDNEIO_01167 8.6e-11 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MDEDNEIO_01168 1.3e-202 L Transposase, Mutator family
MDEDNEIO_01170 1.2e-119
MDEDNEIO_01171 1.3e-271 S Psort location Cytoplasmic, score
MDEDNEIO_01172 0.0 sprF 4.6.1.1 M Cell surface antigen C-terminus
MDEDNEIO_01173 9.8e-48 V ABC-2 type transporter
MDEDNEIO_01174 4.3e-41 V ATPase activity
MDEDNEIO_01175 3.2e-18 V Lanthionine synthetase C-like protein
MDEDNEIO_01176 6.4e-24 spaB S Lantibiotic biosynthesis dehydratase C-term
MDEDNEIO_01178 6.8e-81
MDEDNEIO_01179 2.2e-99
MDEDNEIO_01180 1.3e-119 V ATPases associated with a variety of cellular activities
MDEDNEIO_01181 1.6e-70 L Transposase and inactivated derivatives IS30 family
MDEDNEIO_01182 5e-42
MDEDNEIO_01183 4.9e-72 yycO S PFAM Orthopoxvirus protein of
MDEDNEIO_01184 1.4e-29
MDEDNEIO_01185 2e-93 S Domain of unknown function (DUF4192)
MDEDNEIO_01186 2.4e-60 K helix_turn_helix, Lux Regulon
MDEDNEIO_01187 2.8e-56 2.7.13.3 T Histidine kinase
MDEDNEIO_01188 2.6e-172 L Phage integrase family
MDEDNEIO_01189 9.6e-87 6.3.5.5 HJ Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)
MDEDNEIO_01190 1.6e-94 F ATP-grasp domain
MDEDNEIO_01191 4.7e-78 G MFS/sugar transport protein
MDEDNEIO_01192 7.4e-70 L Phage integrase family
MDEDNEIO_01194 2.4e-122 V ABC transporter
MDEDNEIO_01197 3e-17 U Type IV secretory system Conjugative DNA transfer
MDEDNEIO_01198 2.6e-231 T Histidine kinase
MDEDNEIO_01199 4.6e-126 K helix_turn_helix, Lux Regulon
MDEDNEIO_01200 2.5e-121 V ABC transporter
MDEDNEIO_01201 2.3e-15
MDEDNEIO_01202 2.2e-290 3.4.21.83 E Prolyl oligopeptidase family
MDEDNEIO_01203 9.7e-127 V ABC transporter
MDEDNEIO_01204 2.3e-225 V Efflux ABC transporter, permease protein
MDEDNEIO_01205 6.1e-67
MDEDNEIO_01206 5.2e-41
MDEDNEIO_01207 1.4e-194 T Histidine kinase
MDEDNEIO_01208 4.9e-117 K Bacterial regulatory proteins, luxR family
MDEDNEIO_01209 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MDEDNEIO_01210 5.9e-18 araE EGP Major facilitator Superfamily
MDEDNEIO_01211 1e-98 cydD V ABC transporter transmembrane region
MDEDNEIO_01212 5.9e-125 cydD V ABC transporter transmembrane region
MDEDNEIO_01213 4.3e-247 araE EGP Major facilitator Superfamily
MDEDNEIO_01214 9.1e-101 2.7.13.3 T Histidine kinase
MDEDNEIO_01215 4.3e-41 K helix_turn_helix, Lux Regulon
MDEDNEIO_01216 2.2e-19 S Bacteriocin (Lactococcin_972)
MDEDNEIO_01217 5.7e-243 XK27_10205
MDEDNEIO_01218 4.7e-101 V ABC transporter
MDEDNEIO_01219 1.1e-26
MDEDNEIO_01220 2.3e-25 L Transposase
MDEDNEIO_01221 2.1e-19 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MDEDNEIO_01222 2.8e-170 K helix_turn _helix lactose operon repressor
MDEDNEIO_01223 6e-81 ganB 3.2.1.89 G Glycosyl hydrolase family 53
MDEDNEIO_01224 6.7e-125 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
MDEDNEIO_01225 3.7e-134 L Protein of unknown function (DUF1524)
MDEDNEIO_01226 4.4e-266 S Domain of unknown function (DUF4143)
MDEDNEIO_01227 2.1e-204 mntH P H( )-stimulated, divalent metal cation uptake system
MDEDNEIO_01228 5.6e-260 EGP Major facilitator Superfamily
MDEDNEIO_01229 8.4e-132 S AAA ATPase domain
MDEDNEIO_01230 3e-170 S Psort location Cytoplasmic, score 7.50
MDEDNEIO_01231 8.3e-43 V efflux transmembrane transporter activity
MDEDNEIO_01232 1.5e-149 L Transposase and inactivated derivatives IS30 family
MDEDNEIO_01233 3.7e-76 L Phage integrase family
MDEDNEIO_01234 6.7e-234 S AAA domain
MDEDNEIO_01235 1.5e-308 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MDEDNEIO_01236 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MDEDNEIO_01237 0.0 yjjP S Threonine/Serine exporter, ThrE
MDEDNEIO_01238 1.9e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
MDEDNEIO_01239 4.3e-98 EGP Major facilitator Superfamily
MDEDNEIO_01240 1.8e-287 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDEDNEIO_01241 1.5e-55 K Psort location Cytoplasmic, score
MDEDNEIO_01242 3.4e-107 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
MDEDNEIO_01243 4.1e-198 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDEDNEIO_01244 5.7e-38 S Protein of unknown function (DUF3073)
MDEDNEIO_01245 6.1e-112 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDEDNEIO_01246 3.2e-209 2.7.13.3 T Histidine kinase
MDEDNEIO_01247 2.5e-232 EGP Major Facilitator Superfamily
MDEDNEIO_01248 1.7e-75 I Sterol carrier protein
MDEDNEIO_01249 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MDEDNEIO_01250 1.7e-31
MDEDNEIO_01251 2.9e-125 gluP 3.4.21.105 S Rhomboid family
MDEDNEIO_01252 6.2e-79 crgA D Involved in cell division
MDEDNEIO_01253 4.1e-107 S Bacterial protein of unknown function (DUF881)
MDEDNEIO_01254 2.6e-233 srtA 3.4.22.70 M Sortase family
MDEDNEIO_01255 1.1e-118 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
MDEDNEIO_01256 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
MDEDNEIO_01257 1.7e-171 T Protein tyrosine kinase
MDEDNEIO_01258 9.5e-259 pbpA M penicillin-binding protein
MDEDNEIO_01259 3.5e-251 rodA D Belongs to the SEDS family
MDEDNEIO_01260 1.1e-239 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
MDEDNEIO_01261 8e-59 fhaB T Inner membrane component of T3SS, cytoplasmic domain
MDEDNEIO_01262 2.6e-129 fhaA T Protein of unknown function (DUF2662)
MDEDNEIO_01263 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
MDEDNEIO_01264 7.6e-205 pldB 3.1.1.5 I Serine aminopeptidase, S33
MDEDNEIO_01265 4.1e-146 yddG EG EamA-like transporter family
MDEDNEIO_01266 2.7e-231 S Putative esterase
MDEDNEIO_01267 0.0 lysX S Uncharacterised conserved protein (DUF2156)
MDEDNEIO_01268 3.3e-183 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDEDNEIO_01269 9e-119 S Pyridoxamine 5'-phosphate oxidase
MDEDNEIO_01270 6e-63 S Domain of unknown function (DUF4928)
MDEDNEIO_01271 1e-24 S Domain of unknown function (DUF4928)
MDEDNEIO_01272 4.4e-166 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MDEDNEIO_01273 1.1e-50 ybjQ S Putative heavy-metal-binding
MDEDNEIO_01274 3.8e-127 yplQ S Haemolysin-III related
MDEDNEIO_01275 5.1e-64 hsp20 O Hsp20/alpha crystallin family
MDEDNEIO_01276 1.1e-59 yoaZ S PfpI family
MDEDNEIO_01278 4.4e-32 T Toxic component of a toxin-antitoxin (TA) module
MDEDNEIO_01281 1e-25 L Transposase DDE domain
MDEDNEIO_01283 1.2e-257 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MDEDNEIO_01284 9.8e-246 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
MDEDNEIO_01285 0.0 cadA P E1-E2 ATPase
MDEDNEIO_01286 3.5e-196 urtA E Receptor family ligand binding region
MDEDNEIO_01287 4.2e-129 urtB U Branched-chain amino acid transport system / permease component
MDEDNEIO_01288 1.3e-159 urtC U Branched-chain amino acid transport system / permease component
MDEDNEIO_01289 2.6e-113 urtD S Branched-chain amino acid ATP-binding cassette transporter
MDEDNEIO_01290 1.1e-98 urtE E ABC transporter
MDEDNEIO_01291 3.9e-110 hoxN S rRNA processing
MDEDNEIO_01292 1.1e-95 ureB 3.5.1.5 E Urease, gamma subunit
MDEDNEIO_01293 3e-304 ureC 3.5.1.5 E Urease alpha-subunit, N-terminal domain
MDEDNEIO_01294 2.5e-86 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MDEDNEIO_01295 3.1e-81 ureF J Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MDEDNEIO_01296 2.4e-99 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MDEDNEIO_01297 1.1e-92 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MDEDNEIO_01299 5e-268 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
MDEDNEIO_01300 8.4e-160 htpX O Belongs to the peptidase M48B family
MDEDNEIO_01301 1.3e-114 3.2.1.4 GH5,GH9 S acid phosphatase activity
MDEDNEIO_01303 8.2e-205 EGP Major Facilitator Superfamily
MDEDNEIO_01304 2.1e-128 E IrrE N-terminal-like domain
MDEDNEIO_01305 8e-73 S Domain of unknown function (DUF4411)
MDEDNEIO_01306 7.1e-21 L Transposase and inactivated derivatives IS30 family
MDEDNEIO_01307 1.5e-34 K UTRA
MDEDNEIO_01308 2.8e-140 yegU O ADP-ribosylglycohydrolase
MDEDNEIO_01309 1.1e-98 yegV G pfkB family carbohydrate kinase
MDEDNEIO_01310 3.7e-247 U Permease for cytosine/purines, uracil, thiamine, allantoin
MDEDNEIO_01311 4.5e-84 Q Isochorismatase family
MDEDNEIO_01312 7.3e-28 L Transposase DDE domain
MDEDNEIO_01313 1.7e-119 mug 3.2.2.28, 6.3.3.2 L Uracil DNA glycosylase superfamily
MDEDNEIO_01314 1.4e-206 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MDEDNEIO_01315 9.9e-22 D AAA domain, putative AbiEii toxin, Type IV TA system
MDEDNEIO_01316 1.9e-14 S AAA ATPase domain
MDEDNEIO_01317 2.2e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDEDNEIO_01318 2.4e-281 clcA P Voltage gated chloride channel
MDEDNEIO_01319 1.4e-134 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDEDNEIO_01320 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDEDNEIO_01321 1.2e-202 K helix_turn _helix lactose operon repressor
MDEDNEIO_01322 3.3e-299 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
MDEDNEIO_01323 4.9e-272 scrT G Transporter major facilitator family protein
MDEDNEIO_01324 1.6e-239 yhjE EGP Sugar (and other) transporter
MDEDNEIO_01326 2.5e-11 L Phage integrase family
MDEDNEIO_01328 2e-19
MDEDNEIO_01329 1.7e-110
MDEDNEIO_01330 5.5e-122
MDEDNEIO_01333 1.3e-205 EGP Major facilitator Superfamily
MDEDNEIO_01335 0.0 yjjK S ATP-binding cassette protein, ChvD family
MDEDNEIO_01336 2.5e-169 tesB I Thioesterase-like superfamily
MDEDNEIO_01337 3.2e-92 S Protein of unknown function (DUF3180)
MDEDNEIO_01338 5.2e-262 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MDEDNEIO_01339 2.4e-156 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MDEDNEIO_01340 4.9e-105 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
MDEDNEIO_01342 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDEDNEIO_01343 4e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MDEDNEIO_01344 4.3e-214 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDEDNEIO_01345 1.3e-255 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
MDEDNEIO_01346 1.9e-300
MDEDNEIO_01347 2e-144 natA V ATPases associated with a variety of cellular activities
MDEDNEIO_01348 1.2e-230 epsG M Glycosyl transferase family 21
MDEDNEIO_01349 1.1e-266 S AI-2E family transporter
MDEDNEIO_01350 2e-177 3.4.14.13 M Glycosyltransferase like family 2
MDEDNEIO_01351 9.2e-201 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
MDEDNEIO_01352 4.2e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
MDEDNEIO_01355 1.2e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MDEDNEIO_01356 2.7e-157 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDEDNEIO_01358 1.1e-40
MDEDNEIO_01359 2.8e-16
MDEDNEIO_01360 6.3e-216 S Helix-turn-helix domain
MDEDNEIO_01361 1.6e-68 S Transcription factor WhiB
MDEDNEIO_01362 6e-141 D AAA domain
MDEDNEIO_01363 1.2e-67
MDEDNEIO_01364 5.2e-24
MDEDNEIO_01365 2.4e-204 G Glycosyl hydrolase family 20, domain 2
MDEDNEIO_01366 1.5e-31 3.1.3.18 S phosphoglycolate phosphatase activity
MDEDNEIO_01367 1.3e-139 G Extracellular solute-binding protein
MDEDNEIO_01368 1.1e-117 YSH1 S Metallo-beta-lactamase superfamily
MDEDNEIO_01369 5e-100 gtsC P Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01370 7.3e-103 gtsB G PFAM Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01371 3.5e-128 malK P Belongs to the ABC transporter superfamily
MDEDNEIO_01372 2.2e-93 M1-431 S Protein of unknown function (DUF1706)
MDEDNEIO_01373 6.8e-168 L Helix-turn-helix domain
MDEDNEIO_01374 9.9e-41 L Resolvase, N terminal domain
MDEDNEIO_01375 4.1e-213 phoN I PAP2 superfamily
MDEDNEIO_01376 2.8e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDEDNEIO_01377 9.8e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDEDNEIO_01378 2.8e-90 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MDEDNEIO_01379 2e-202 G Bacterial extracellular solute-binding protein
MDEDNEIO_01380 8e-128 ugpE G Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01381 2.9e-131 ugpA P Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01382 5.2e-158 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MDEDNEIO_01383 1.2e-156 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDEDNEIO_01384 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MDEDNEIO_01385 3.1e-72 2.3.1.57 K Acetyltransferase (GNAT) domain
MDEDNEIO_01386 4.9e-156 fahA Q Fumarylacetoacetate (FAA) hydrolase family
MDEDNEIO_01387 1.5e-23 S Domain of unknown function (DUF4190)
MDEDNEIO_01388 4.9e-66 glf 5.4.99.9 M UDP-galactopyranose mutase
MDEDNEIO_01389 1.2e-116 V VanZ like family
MDEDNEIO_01390 5.3e-96 rpoE4 K Sigma-70 region 2
MDEDNEIO_01391 1.1e-22 S Psort location CytoplasmicMembrane, score
MDEDNEIO_01392 2.1e-106
MDEDNEIO_01393 1.1e-136
MDEDNEIO_01394 1.1e-169 yfiL V ATPases associated with a variety of cellular activities
MDEDNEIO_01395 1.1e-65
MDEDNEIO_01396 5.2e-29 V ABC transporter transmembrane region
MDEDNEIO_01397 3.3e-79 V ABC transporter
MDEDNEIO_01398 2.7e-77 V FtsX-like permease family
MDEDNEIO_01399 2.5e-51 T Histidine kinase
MDEDNEIO_01400 1.9e-74 K Bacterial regulatory proteins, luxR family
MDEDNEIO_01401 1.5e-97 KLT Protein kinase domain
MDEDNEIO_01403 9.5e-35 ptrB 3.4.21.83 E Prolyl oligopeptidase, N-terminal beta-propeller domain
MDEDNEIO_01404 1.1e-75 G Glycosyl hydrolase family 20, domain 2
MDEDNEIO_01405 6.4e-243 L Phage integrase family
MDEDNEIO_01407 3.9e-16
MDEDNEIO_01408 1.4e-126 3.6.4.12 K Divergent AAA domain protein
MDEDNEIO_01410 1.2e-06 S SdpI/YhfL protein family
MDEDNEIO_01411 1.2e-26 K Psort location Cytoplasmic, score
MDEDNEIO_01412 7.3e-277 V FtsX-like permease family
MDEDNEIO_01413 1.2e-110 V ABC transporter
MDEDNEIO_01414 2.9e-36 T PhoQ Sensor
MDEDNEIO_01415 1.5e-38
MDEDNEIO_01420 2.9e-70 cpdB 3.1.3.6, 3.1.4.16 F Calcineurin-like phosphoesterase
MDEDNEIO_01421 1.7e-81 3.6.1.63 U Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01422 3.4e-77 phnE 3.6.1.63 U Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01423 2e-82 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MDEDNEIO_01424 1.8e-114 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
MDEDNEIO_01425 4.1e-36 K Helix-turn-helix domain, rpiR family
MDEDNEIO_01426 2.2e-30 S phosphoglycolate phosphatase activity
MDEDNEIO_01427 4.6e-201 S Domain of unknown function (DUF4143)
MDEDNEIO_01428 7.8e-146 S Protein of unknown function DUF45
MDEDNEIO_01429 6.7e-256 S Domain of unknown function (DUF4143)
MDEDNEIO_01430 2.1e-82 dps P Belongs to the Dps family
MDEDNEIO_01431 2.7e-236 ytfL P Transporter associated domain
MDEDNEIO_01432 1.4e-201 S AAA ATPase domain
MDEDNEIO_01433 3e-84 V Forkhead associated domain
MDEDNEIO_01434 1.6e-120 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MDEDNEIO_01435 3.8e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
MDEDNEIO_01436 0.0 trxB1 1.8.1.9 C Thioredoxin domain
MDEDNEIO_01437 9.5e-239 yhjX EGP Major facilitator Superfamily
MDEDNEIO_01438 5.9e-41 S Psort location Cytoplasmic, score
MDEDNEIO_01439 2.6e-183 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
MDEDNEIO_01440 1.2e-125 lacG G Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01441 2e-122 G Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01442 4.8e-174 srrA1 G Bacterial extracellular solute-binding protein
MDEDNEIO_01443 2.3e-50 3.2.1.97 GH101 M Cell wall-binding repeat protein
MDEDNEIO_01444 1.6e-113 cps3I G Psort location CytoplasmicMembrane, score 9.99
MDEDNEIO_01445 3.7e-214
MDEDNEIO_01446 2.8e-158 ykoT 2.4.1.83 GT2 M Glycosyl transferase family 2
MDEDNEIO_01447 2.1e-88
MDEDNEIO_01448 8.5e-170 V MacB-like periplasmic core domain
MDEDNEIO_01449 5e-128 V ATPases associated with a variety of cellular activities
MDEDNEIO_01450 3.8e-119 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MDEDNEIO_01451 4.3e-28 EGP Major Facilitator Superfamily
MDEDNEIO_01452 6.5e-22 K trisaccharide binding
MDEDNEIO_01453 1e-109 K COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDEDNEIO_01454 1.8e-34 T PhoQ Sensor
MDEDNEIO_01455 3.3e-50
MDEDNEIO_01456 5.2e-121
MDEDNEIO_01459 1.9e-107
MDEDNEIO_01460 1.8e-26 S Polyketide cyclase / dehydrase and lipid transport
MDEDNEIO_01462 8.4e-201 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MDEDNEIO_01463 1.8e-51 bioN P Cobalt transport protein
MDEDNEIO_01464 3e-72 cbiO P ATPases associated with a variety of cellular activities
MDEDNEIO_01465 1.5e-58 bioY S BioY family
MDEDNEIO_01466 4.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MDEDNEIO_01467 1.3e-145 S Psort location Cytoplasmic, score
MDEDNEIO_01468 5.9e-191 K Transcriptional regulator
MDEDNEIO_01469 1.2e-265 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
MDEDNEIO_01470 4.3e-85 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
MDEDNEIO_01471 1.3e-185 K Psort location Cytoplasmic, score
MDEDNEIO_01472 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
MDEDNEIO_01473 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
MDEDNEIO_01474 0.0 dnaK O Heat shock 70 kDa protein
MDEDNEIO_01475 7e-55 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDEDNEIO_01476 5.7e-170 dnaJ1 O DnaJ molecular chaperone homology domain
MDEDNEIO_01477 3.4e-98 hspR K transcriptional regulator, MerR family
MDEDNEIO_01478 5.5e-213 F Psort location CytoplasmicMembrane, score 10.00
MDEDNEIO_01479 1.2e-208 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
MDEDNEIO_01480 4.2e-230 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
MDEDNEIO_01481 3.6e-91 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
MDEDNEIO_01482 3.8e-38 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
MDEDNEIO_01483 2e-123 S HAD hydrolase, family IA, variant 3
MDEDNEIO_01484 6.1e-134 dedA S SNARE associated Golgi protein
MDEDNEIO_01485 5e-128 cpaE D bacterial-type flagellum organization
MDEDNEIO_01486 1.5e-192 cpaF U Type II IV secretion system protein
MDEDNEIO_01487 1.7e-106 U Type ii secretion system
MDEDNEIO_01488 9.7e-101 gspF NU Type II secretion system (T2SS), protein F
MDEDNEIO_01489 4.6e-40 S Protein of unknown function (DUF4244)
MDEDNEIO_01490 1.5e-53 S TIGRFAM helicase secretion neighborhood TadE-like protein
MDEDNEIO_01491 3.5e-213 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
MDEDNEIO_01492 4.1e-99 K Bacterial regulatory proteins, tetR family
MDEDNEIO_01493 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
MDEDNEIO_01494 2.2e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDEDNEIO_01495 2.6e-203 3.4.22.70 M Sortase family
MDEDNEIO_01496 2.8e-53 S Psort location Cytoplasmic, score
MDEDNEIO_01497 2.3e-131 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MDEDNEIO_01498 8e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
MDEDNEIO_01499 9.3e-211 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDEDNEIO_01500 3.5e-114
MDEDNEIO_01501 3.3e-310 S Calcineurin-like phosphoesterase
MDEDNEIO_01502 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MDEDNEIO_01503 9.8e-132 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MDEDNEIO_01504 1.8e-195 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MDEDNEIO_01505 5.6e-167 3.6.1.27 I PAP2 superfamily
MDEDNEIO_01506 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDEDNEIO_01507 3.1e-122 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDEDNEIO_01508 2e-203 holB 2.7.7.7 L DNA polymerase III
MDEDNEIO_01509 5.6e-99 K helix_turn _helix lactose operon repressor
MDEDNEIO_01510 5.6e-37 ptsH G PTS HPr component phosphorylation site
MDEDNEIO_01512 1.4e-290 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDEDNEIO_01513 5.6e-106 S Phosphatidylethanolamine-binding protein
MDEDNEIO_01514 0.0 pepD E Peptidase family C69
MDEDNEIO_01515 2e-291 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
MDEDNEIO_01516 5.1e-62 S Macrophage migration inhibitory factor (MIF)
MDEDNEIO_01517 2.4e-95 S GtrA-like protein
MDEDNEIO_01518 1.9e-259 EGP Major facilitator Superfamily
MDEDNEIO_01519 2.9e-122 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
MDEDNEIO_01520 4.9e-157
MDEDNEIO_01521 2.6e-163 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
MDEDNEIO_01522 3.2e-142 S Protein of unknown function (DUF805)
MDEDNEIO_01523 3.6e-293 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDEDNEIO_01526 4.4e-67
MDEDNEIO_01527 2.2e-135 yoaK S Protein of unknown function (DUF1275)
MDEDNEIO_01528 9e-49 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MDEDNEIO_01530 8e-299
MDEDNEIO_01531 0.0 efeU_1 P Iron permease FTR1 family
MDEDNEIO_01532 4.7e-107 tpd P Fe2+ transport protein
MDEDNEIO_01533 2.5e-231 S Predicted membrane protein (DUF2318)
MDEDNEIO_01534 2.9e-211 macB_2 V ABC transporter permease
MDEDNEIO_01535 3.5e-214 Z012_06715 V FtsX-like permease family
MDEDNEIO_01536 5.9e-146 macB V ABC transporter, ATP-binding protein
MDEDNEIO_01537 1e-64 S FMN_bind
MDEDNEIO_01538 3.2e-104 K Psort location Cytoplasmic, score 8.87
MDEDNEIO_01539 3.6e-307 pip S YhgE Pip domain protein
MDEDNEIO_01540 0.0 pip S YhgE Pip domain protein
MDEDNEIO_01541 1.5e-231 S Putative ABC-transporter type IV
MDEDNEIO_01542 9.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDEDNEIO_01543 1e-132 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MDEDNEIO_01544 3.2e-181 opcA G Glucose-6-phosphate dehydrogenase subunit
MDEDNEIO_01545 8e-301 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDEDNEIO_01547 1.2e-39
MDEDNEIO_01549 8.1e-259 pepD E Peptidase family C69
MDEDNEIO_01550 6.4e-185 XK27_01805 M Glycosyltransferase like family 2
MDEDNEIO_01551 1.1e-122 icaR K Bacterial regulatory proteins, tetR family
MDEDNEIO_01552 2.8e-45 S Protein of unknown function (DUF2089)
MDEDNEIO_01553 1.7e-16
MDEDNEIO_01554 1e-168 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDEDNEIO_01555 6.9e-229 amt U Ammonium Transporter Family
MDEDNEIO_01556 1e-54 glnB K Nitrogen regulatory protein P-II
MDEDNEIO_01557 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
MDEDNEIO_01558 1e-249 dinF V MatE
MDEDNEIO_01559 3.3e-278 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MDEDNEIO_01560 3.6e-258 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
MDEDNEIO_01561 7e-141 cobQ S CobB/CobQ-like glutamine amidotransferase domain
MDEDNEIO_01562 5.2e-36 S granule-associated protein
MDEDNEIO_01563 0.0 ubiB S ABC1 family
MDEDNEIO_01564 7.8e-133 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MDEDNEIO_01565 5.8e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDEDNEIO_01566 4.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
MDEDNEIO_01567 4.3e-70 ssb1 L Single-stranded DNA-binding protein
MDEDNEIO_01568 2.6e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDEDNEIO_01569 1.9e-69 rplI J Binds to the 23S rRNA
MDEDNEIO_01571 4.1e-39 L Transposase
MDEDNEIO_01572 6.5e-117
MDEDNEIO_01573 2.6e-129 V ABC transporter
MDEDNEIO_01574 8.2e-137 sagI S ABC-2 type transporter
MDEDNEIO_01575 1.7e-75 V ATPases associated with a variety of cellular activities
MDEDNEIO_01576 6.2e-107 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDEDNEIO_01577 1.1e-201 2.7.13.3 T Histidine kinase
MDEDNEIO_01578 9.7e-201 EGP Major Facilitator Superfamily
MDEDNEIO_01579 7.7e-302 merA 1.16.1.1 H Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0)
MDEDNEIO_01580 1.5e-255 tnpA1 L Helix-turn-helix domain of transposase family ISL3
MDEDNEIO_01581 6.8e-43
MDEDNEIO_01582 0.0 E Sodium:solute symporter family
MDEDNEIO_01583 1e-232 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
MDEDNEIO_01585 4.3e-146 cobB2 K Sir2 family
MDEDNEIO_01586 1.9e-80 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
MDEDNEIO_01587 1.7e-22 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
MDEDNEIO_01588 1.2e-94 uhpT EGP Major facilitator Superfamily
MDEDNEIO_01590 1.5e-36
MDEDNEIO_01591 2.4e-238 mloB K Putative DNA-binding domain
MDEDNEIO_01592 1.6e-195 L PFAM Integrase catalytic
MDEDNEIO_01593 1.8e-116 S EamA-like transporter family
MDEDNEIO_01594 8.8e-18 L Transposase
MDEDNEIO_01595 5.1e-157 S AAA ATPase domain
MDEDNEIO_01597 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MDEDNEIO_01598 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MDEDNEIO_01599 3.4e-269 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MDEDNEIO_01601 9.5e-169 hisN 3.1.3.25 G Inositol monophosphatase family
MDEDNEIO_01602 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
MDEDNEIO_01603 3.1e-284 arc O AAA ATPase forming ring-shaped complexes
MDEDNEIO_01604 1.7e-125 apl 3.1.3.1 S SNARE associated Golgi protein
MDEDNEIO_01605 2.7e-126 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
MDEDNEIO_01606 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDEDNEIO_01607 3.3e-132 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MDEDNEIO_01608 3.1e-181 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDEDNEIO_01609 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
MDEDNEIO_01610 2.5e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDEDNEIO_01611 1.6e-227 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDEDNEIO_01612 2e-218 vex3 V ABC transporter permease
MDEDNEIO_01613 1.2e-209 vex1 V Efflux ABC transporter, permease protein
MDEDNEIO_01614 5.4e-110 vex2 V ABC transporter, ATP-binding protein
MDEDNEIO_01615 1.1e-97 ptpA 3.1.3.48 T low molecular weight
MDEDNEIO_01616 2.8e-125 folA 1.5.1.3 H dihydrofolate reductase
MDEDNEIO_01618 1.4e-172 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDEDNEIO_01619 6.9e-74 attW O OsmC-like protein
MDEDNEIO_01620 2.3e-187 T Universal stress protein family
MDEDNEIO_01621 8.8e-104 M NlpC/P60 family
MDEDNEIO_01622 1e-79 M NlpC/P60 family
MDEDNEIO_01623 3e-165 usp 3.5.1.28 CBM50 S CHAP domain
MDEDNEIO_01624 2e-211 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MDEDNEIO_01625 4.3e-37
MDEDNEIO_01626 3e-194 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MDEDNEIO_01627 1.7e-114 phoU P Plays a role in the regulation of phosphate uptake
MDEDNEIO_01628 1.4e-138 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDEDNEIO_01629 1.5e-25 T Histidine kinase
MDEDNEIO_01630 2.6e-41 K helix_turn_helix, Lux Regulon
MDEDNEIO_01632 8.1e-16
MDEDNEIO_01633 4.3e-139 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MDEDNEIO_01634 3.2e-24 2.7.13.3 T Histidine kinase
MDEDNEIO_01635 5.4e-39 K helix_turn_helix, Lux Regulon
MDEDNEIO_01639 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MDEDNEIO_01641 9.8e-206 araJ EGP Major facilitator Superfamily
MDEDNEIO_01642 0.0 phoC 3.1.3.5 I PAP2 superfamily
MDEDNEIO_01643 2.6e-278 S Domain of unknown function (DUF4037)
MDEDNEIO_01644 1.2e-112 S Protein of unknown function (DUF4125)
MDEDNEIO_01645 1.6e-280 S alpha beta
MDEDNEIO_01646 1.4e-55
MDEDNEIO_01647 1e-169 pspC KT PspC domain
MDEDNEIO_01648 5.8e-225 tcsS3 KT PspC domain
MDEDNEIO_01649 2.7e-110 degU K helix_turn_helix, Lux Regulon
MDEDNEIO_01650 9.8e-170 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MDEDNEIO_01651 6.2e-301 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MDEDNEIO_01652 9.3e-195 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
MDEDNEIO_01653 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
MDEDNEIO_01655 6.6e-240 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDEDNEIO_01656 1.7e-202 I Diacylglycerol kinase catalytic domain
MDEDNEIO_01657 1.4e-159 arbG K CAT RNA binding domain
MDEDNEIO_01658 0.0 crr 2.7.1.193 G pts system, glucose-specific IIABC component
MDEDNEIO_01659 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MDEDNEIO_01660 6.9e-187 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MDEDNEIO_01661 9e-69 K Transcriptional regulator
MDEDNEIO_01662 2.2e-280 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MDEDNEIO_01664 5.6e-122 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDEDNEIO_01665 1.5e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MDEDNEIO_01667 3.9e-92
MDEDNEIO_01668 4e-276 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDEDNEIO_01669 2.8e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
MDEDNEIO_01670 9.9e-211 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDEDNEIO_01671 3.6e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDEDNEIO_01672 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDEDNEIO_01673 5.6e-184 nusA K Participates in both transcription termination and antitermination
MDEDNEIO_01674 3.1e-125
MDEDNEIO_01675 2e-242 G Bacterial extracellular solute-binding protein
MDEDNEIO_01676 2.4e-173 P Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01677 1.4e-159 P Binding-protein-dependent transport system inner membrane component
MDEDNEIO_01678 2.6e-12 L Integrase core domain
MDEDNEIO_01680 1.5e-218 S Psort location Cytoplasmic, score
MDEDNEIO_01681 8.8e-150 E Transglutaminase/protease-like homologues
MDEDNEIO_01682 0.0 gcs2 S A circularly permuted ATPgrasp
MDEDNEIO_01683 1.4e-167 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDEDNEIO_01684 1.7e-61 rplQ J Ribosomal protein L17
MDEDNEIO_01685 1.7e-182 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDEDNEIO_01686 1.5e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDEDNEIO_01687 3.6e-61 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDEDNEIO_01688 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MDEDNEIO_01689 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDEDNEIO_01690 6.5e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDEDNEIO_01691 7.6e-247 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDEDNEIO_01692 1.1e-75 rplO J binds to the 23S rRNA
MDEDNEIO_01693 9.2e-26 rpmD J Ribosomal protein L30p/L7e
MDEDNEIO_01694 1.5e-95 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDEDNEIO_01695 2.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDEDNEIO_01696 1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDEDNEIO_01697 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDEDNEIO_01698 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDEDNEIO_01699 4.4e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDEDNEIO_01700 1.8e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDEDNEIO_01701 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDEDNEIO_01702 6.4e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDEDNEIO_01703 4.1e-37 rpmC J Belongs to the universal ribosomal protein uL29 family
MDEDNEIO_01704 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDEDNEIO_01705 2.4e-102 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDEDNEIO_01706 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDEDNEIO_01707 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDEDNEIO_01708 8e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDEDNEIO_01709 3.4e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDEDNEIO_01710 1.2e-115 rplD J Forms part of the polypeptide exit tunnel
MDEDNEIO_01711 1.1e-115 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDEDNEIO_01712 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
MDEDNEIO_01713 1.5e-143 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MDEDNEIO_01714 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MDEDNEIO_01715 1.2e-224 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MDEDNEIO_01716 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MDEDNEIO_01717 3.7e-82 rpsI J Belongs to the universal ribosomal protein uS9 family
MDEDNEIO_01718 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDEDNEIO_01719 2e-76 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
MDEDNEIO_01720 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
MDEDNEIO_01721 4.9e-107
MDEDNEIO_01722 5.5e-110 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
MDEDNEIO_01723 8.7e-187 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDEDNEIO_01726 4.3e-232 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDEDNEIO_01727 6e-214 dapC E Aminotransferase class I and II
MDEDNEIO_01728 1.7e-59 fdxA C 4Fe-4S binding domain
MDEDNEIO_01729 4.4e-267 E aromatic amino acid transport protein AroP K03293
MDEDNEIO_01730 1.8e-218 murB 1.3.1.98 M Cell wall formation
MDEDNEIO_01731 4.1e-25 rpmG J Ribosomal protein L33
MDEDNEIO_01735 6.1e-42 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MDEDNEIO_01736 6.7e-47 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDEDNEIO_01737 1.2e-186
MDEDNEIO_01738 4.3e-126 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
MDEDNEIO_01739 4.8e-118 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
MDEDNEIO_01740 2.5e-31 fmdB S Putative regulatory protein
MDEDNEIO_01741 1.6e-93 flgA NO SAF
MDEDNEIO_01742 6e-31
MDEDNEIO_01743 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
MDEDNEIO_01744 3.1e-187 T Forkhead associated domain
MDEDNEIO_01745 1.1e-33 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDEDNEIO_01746 3.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDEDNEIO_01747 3.5e-132 3.2.1.8 S alpha beta
MDEDNEIO_01748 3.9e-246 pbuO S Permease family
MDEDNEIO_01749 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MDEDNEIO_01750 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDEDNEIO_01751 2.3e-187 lanT 3.6.3.27 V ABC transporter
MDEDNEIO_01752 2.3e-153 cbiO V ATPases associated with a variety of cellular activities
MDEDNEIO_01754 7.3e-78 L Transposase
MDEDNEIO_01755 1.8e-114
MDEDNEIO_01756 4.9e-51
MDEDNEIO_01757 2.4e-20 3.2.2.9 T Nacht domain
MDEDNEIO_01758 7.9e-110 M domain protein
MDEDNEIO_01759 1.8e-113 1.3.98.1, 3.2.1.21 GH3 M Conserved repeat domain
MDEDNEIO_01760 1.6e-27
MDEDNEIO_01761 1.3e-91 L Transposase
MDEDNEIO_01762 3.5e-116 ligA 2.7.7.7, 6.5.1.2 L Exonuclease, DNA polymerase III, epsilon subunit family
MDEDNEIO_01763 1.1e-30 ligA 2.7.7.7, 6.5.1.2 L Exonuclease, DNA polymerase III, epsilon subunit family
MDEDNEIO_01764 2.6e-135
MDEDNEIO_01765 3e-28
MDEDNEIO_01768 7.2e-40 S Conserved Protein
MDEDNEIO_01771 1.7e-29 K Transcriptional regulator
MDEDNEIO_01772 1.5e-180 int L Phage integrase, N-terminal SAM-like domain
MDEDNEIO_01774 1e-40 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
MDEDNEIO_01775 5.9e-89 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDEDNEIO_01776 2.7e-98 K helix_turn _helix lactose operon repressor
MDEDNEIO_01777 4e-175 msmE G transport
MDEDNEIO_01778 4.2e-12 S addiction module toxin, RelE StbE family
MDEDNEIO_01779 3e-28 relB L RelB antitoxin
MDEDNEIO_01780 3.3e-104 V MatE
MDEDNEIO_01781 0.0 drrC L ABC transporter
MDEDNEIO_01782 7.7e-26 2.7.7.7 L Transposase, Mutator family
MDEDNEIO_01783 1.5e-233 XK27_00240 K Fic/DOC family
MDEDNEIO_01784 3.1e-60 yccF S Inner membrane component domain
MDEDNEIO_01785 8.2e-47 ksgA 2.1.1.182 J Methyltransferase domain
MDEDNEIO_01786 7.7e-61 S Cupin 2, conserved barrel domain protein
MDEDNEIO_01787 1.5e-52 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDEDNEIO_01788 1.1e-36 L RelB antitoxin
MDEDNEIO_01789 2.8e-243 S HipA-like C-terminal domain
MDEDNEIO_01790 1.6e-16 K addiction module antidote protein HigA
MDEDNEIO_01791 1.8e-218 G Transmembrane secretion effector
MDEDNEIO_01792 1.8e-114 K Bacterial regulatory proteins, tetR family
MDEDNEIO_01793 2.2e-11
MDEDNEIO_01794 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
MDEDNEIO_01795 1.8e-260 EGP Transmembrane secretion effector
MDEDNEIO_01796 7.5e-284 KLT Protein tyrosine kinase
MDEDNEIO_01797 4.6e-76 K Psort location Cytoplasmic, score
MDEDNEIO_01798 5e-226
MDEDNEIO_01799 6.4e-40
MDEDNEIO_01800 1.2e-200 S Short C-terminal domain
MDEDNEIO_01801 6.4e-91 S Helix-turn-helix
MDEDNEIO_01802 1.7e-35 feoA P FeoA
MDEDNEIO_01804 6.6e-11
MDEDNEIO_01805 5.6e-131 S Sulfite exporter TauE/SafE
MDEDNEIO_01806 2.1e-55 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDEDNEIO_01808 6.4e-233 EGP Major facilitator Superfamily
MDEDNEIO_01809 1.3e-105 3.1.3.27 E haloacid dehalogenase-like hydrolase
MDEDNEIO_01810 3e-161 3.1.3.73 G Phosphoglycerate mutase family
MDEDNEIO_01811 2.3e-232 rutG F Permease family
MDEDNEIO_01812 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
MDEDNEIO_01814 1.2e-31 EGP Major Facilitator Superfamily
MDEDNEIO_01815 3.5e-257 nplT G Alpha amylase, catalytic domain
MDEDNEIO_01816 9.1e-187 pit P Phosphate transporter family
MDEDNEIO_01817 2.1e-114 MA20_27875 P Protein of unknown function DUF47
MDEDNEIO_01818 4.3e-110 K helix_turn_helix, Lux Regulon
MDEDNEIO_01819 4.2e-229 T Histidine kinase
MDEDNEIO_01820 1.8e-10 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
MDEDNEIO_01821 1.3e-187 V ATPases associated with a variety of cellular activities
MDEDNEIO_01822 1.5e-225 V ABC-2 family transporter protein
MDEDNEIO_01823 4.2e-251 V ABC-2 family transporter protein
MDEDNEIO_01824 3.5e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MDEDNEIO_01825 1.2e-103 S PIN domain
MDEDNEIO_01826 5.2e-90 K Helix-turn-helix domain
MDEDNEIO_01827 1.4e-31 E GDSL-like Lipase/Acylhydrolase family
MDEDNEIO_01828 1.6e-34 E lipolytic protein G-D-S-L family
MDEDNEIO_01829 3e-194
MDEDNEIO_01830 1.3e-111 3.4.13.21 E Peptidase family S51
MDEDNEIO_01831 1.4e-107 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
MDEDNEIO_01832 2.5e-60 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDEDNEIO_01833 4.2e-167 M pfam nlp p60
MDEDNEIO_01834 9.5e-37 S Protein of unknown function (DUF2975)
MDEDNEIO_01835 2.4e-30 yozG K Cro/C1-type HTH DNA-binding domain
MDEDNEIO_01836 1.2e-239 pbuX F Permease family
MDEDNEIO_01837 2e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDEDNEIO_01838 0.0 pcrA 3.6.4.12 L DNA helicase
MDEDNEIO_01839 3.7e-64 S Domain of unknown function (DUF4418)
MDEDNEIO_01840 5.7e-217 V FtsX-like permease family
MDEDNEIO_01841 6.2e-137 lolD V ABC transporter
MDEDNEIO_01842 4.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDEDNEIO_01843 1.3e-153 S Peptidase C26
MDEDNEIO_01844 2.7e-67 3.5.4.5 F cytidine deaminase activity
MDEDNEIO_01845 5.4e-23 sdpI S SdpI/YhfL protein family
MDEDNEIO_01846 6.1e-111 E Transglutaminase-like superfamily
MDEDNEIO_01847 3e-65 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDEDNEIO_01848 1.2e-48 relB L RelB antitoxin
MDEDNEIO_01849 5.9e-12 L Transposase and inactivated derivatives IS30 family
MDEDNEIO_01850 1.2e-128 pgm3 G Phosphoglycerate mutase family
MDEDNEIO_01851 1.2e-62 WQ51_05790 S Bacterial protein of unknown function (DUF948)
MDEDNEIO_01852 1.6e-35
MDEDNEIO_01853 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDEDNEIO_01854 5.1e-78 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDEDNEIO_01855 1.4e-196 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MDEDNEIO_01856 2.6e-77 3.4.23.43 S Type IV leader peptidase family
MDEDNEIO_01857 1.3e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MDEDNEIO_01858 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MDEDNEIO_01859 7e-80 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MDEDNEIO_01860 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDEDNEIO_01861 1.1e-291 sufB O FeS assembly protein SufB
MDEDNEIO_01862 2.5e-236 sufD O FeS assembly protein SufD
MDEDNEIO_01863 9.2e-144 sufC O FeS assembly ATPase SufC
MDEDNEIO_01864 2.5e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MDEDNEIO_01865 2.6e-100 iscU C SUF system FeS assembly protein, NifU family
MDEDNEIO_01866 2.7e-111 yitW S Iron-sulfur cluster assembly protein
MDEDNEIO_01867 2.9e-240 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MDEDNEIO_01868 6.9e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
MDEDNEIO_01870 7.9e-143 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MDEDNEIO_01871 2.6e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
MDEDNEIO_01872 6.3e-213 phoH T PhoH-like protein
MDEDNEIO_01873 1.4e-101 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDEDNEIO_01874 1.6e-250 corC S CBS domain
MDEDNEIO_01875 3.4e-181 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDEDNEIO_01876 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MDEDNEIO_01877 4.9e-202 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
MDEDNEIO_01878 2.7e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
MDEDNEIO_01879 3.5e-234 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MDEDNEIO_01880 4.4e-194 S alpha beta
MDEDNEIO_01881 1.2e-82 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MDEDNEIO_01882 9e-225 ilvE 2.6.1.42 E Amino-transferase class IV
MDEDNEIO_01883 1.2e-65 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
MDEDNEIO_01884 1.7e-126 S UPF0126 domain
MDEDNEIO_01885 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
MDEDNEIO_01886 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDEDNEIO_01887 5.4e-180 hemN H Involved in the biosynthesis of porphyrin-containing compound
MDEDNEIO_01888 1.5e-134 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MDEDNEIO_01891 2e-178 K helix_turn _helix lactose operon repressor
MDEDNEIO_01892 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
MDEDNEIO_01893 1.7e-303 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MDEDNEIO_01894 2.3e-309 E ABC transporter, substrate-binding protein, family 5
MDEDNEIO_01895 0.0 S Glycosyl hydrolases related to GH101 family, GH129
MDEDNEIO_01896 3.9e-81
MDEDNEIO_01897 5.3e-242 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
MDEDNEIO_01898 7.1e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
MDEDNEIO_01899 7.8e-157 S Sucrose-6F-phosphate phosphohydrolase
MDEDNEIO_01901 7e-90 bcp 1.11.1.15 O Redoxin
MDEDNEIO_01902 1.4e-139
MDEDNEIO_01903 9.4e-62 CP_1020 S zinc finger
MDEDNEIO_01904 6.1e-14 2.5.1.19 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MDEDNEIO_01905 3.1e-31 mazG S MazG-like family
MDEDNEIO_01906 1.2e-206 L Uncharacterized conserved protein (DUF2075)
MDEDNEIO_01907 9.7e-31 S zinc finger
MDEDNEIO_01909 2.1e-19 S Domain of unknown function DUF1828
MDEDNEIO_01910 4e-34 rarD S EamA-like transporter family
MDEDNEIO_01911 1.9e-126 S Plasmid pRiA4b ORF-3-like protein
MDEDNEIO_01912 2.5e-129
MDEDNEIO_01914 2.6e-169 I alpha/beta hydrolase fold
MDEDNEIO_01915 5e-28 ydhF S Aldo/keto reductase family
MDEDNEIO_01916 2.7e-109 S phosphoesterase or phosphohydrolase
MDEDNEIO_01918 2.5e-94 S Phospholipase/Carboxylesterase
MDEDNEIO_01919 1.2e-194 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MDEDNEIO_01920 6.7e-96 sixA 3.6.1.55 T Phosphoglycerate mutase family
MDEDNEIO_01921 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MDEDNEIO_01922 2.4e-153 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
MDEDNEIO_01923 8.2e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDEDNEIO_01924 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MDEDNEIO_01925 2.4e-178 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MDEDNEIO_01926 7e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MDEDNEIO_01927 5.4e-286 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDEDNEIO_01928 1.9e-175 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
MDEDNEIO_01929 4.5e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MDEDNEIO_01930 1.2e-180 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDEDNEIO_01931 1.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDEDNEIO_01932 9e-29
MDEDNEIO_01933 3.2e-206 MA20_36090 S Psort location Cytoplasmic, score 8.87
MDEDNEIO_01934 8.8e-170 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
MDEDNEIO_01935 3.3e-120 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MDEDNEIO_01936 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDEDNEIO_01937 1.8e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
MDEDNEIO_01938 3.2e-163 XK27_08510 KL DEAD-like helicases superfamily
MDEDNEIO_01939 4.9e-58 yeaO K Protein of unknown function, DUF488
MDEDNEIO_01940 4.7e-50 S Virulence protein RhuM family
MDEDNEIO_01942 1.2e-15 yijF S Domain of unknown function (DUF1287)
MDEDNEIO_01943 5e-156 3.6.4.12
MDEDNEIO_01944 3.8e-75
MDEDNEIO_01945 2.6e-64 yeaO K Protein of unknown function, DUF488
MDEDNEIO_01947 9.5e-265 mmuP E amino acid
MDEDNEIO_01948 1.2e-74 2.6.1.76 EGP Major Facilitator Superfamily
MDEDNEIO_01950 4.8e-93 yidC U Membrane protein insertase, YidC Oxa1 family
MDEDNEIO_01951 2.4e-115 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
MDEDNEIO_01952 1.3e-31 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MDEDNEIO_01953 1.2e-53 hipA 2.7.11.1 S kinase activity
MDEDNEIO_01954 6.3e-45 K sequence-specific DNA binding
MDEDNEIO_01955 1.9e-59 G Bacterial extracellular solute-binding protein
MDEDNEIO_01956 1.9e-49
MDEDNEIO_01957 6.3e-199 V AAA domain, putative AbiEii toxin, Type IV TA system
MDEDNEIO_01958 1.9e-142 S ABC-2 family transporter protein
MDEDNEIO_01959 1.6e-136
MDEDNEIO_01960 6.7e-60
MDEDNEIO_01962 7.3e-239 T Histidine kinase
MDEDNEIO_01963 1.1e-119 K helix_turn_helix, Lux Regulon
MDEDNEIO_01966 9.1e-103 M Peptidase family M23
MDEDNEIO_01967 1.2e-254 G ABC transporter substrate-binding protein
MDEDNEIO_01968 4.6e-243 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
MDEDNEIO_01969 2.8e-210 guaB 1.1.1.205 F IMP dehydrogenase family protein
MDEDNEIO_01970 1.5e-70
MDEDNEIO_01971 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
MDEDNEIO_01972 1.3e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDEDNEIO_01973 3e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
MDEDNEIO_01974 7.4e-139 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDEDNEIO_01975 5.5e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MDEDNEIO_01976 4.1e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDEDNEIO_01977 4e-168 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
MDEDNEIO_01978 3.3e-222 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MDEDNEIO_01979 4.7e-76 3.5.1.124 S DJ-1/PfpI family
MDEDNEIO_01980 1.5e-138 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MDEDNEIO_01981 7.6e-70 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MDEDNEIO_01982 7.9e-296 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MDEDNEIO_01983 2.6e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDEDNEIO_01984 1.4e-162 S Protein of unknown function (DUF979)
MDEDNEIO_01985 1.1e-117 S Protein of unknown function (DUF969)
MDEDNEIO_01986 8.4e-301 ybiT S ABC transporter
MDEDNEIO_01987 7.1e-127 yueD S Enoyl-(Acyl carrier protein) reductase
MDEDNEIO_01988 3.1e-161 2.1.1.72 S Protein conserved in bacteria
MDEDNEIO_01989 1.4e-32 S Zincin-like metallopeptidase
MDEDNEIO_01990 7.8e-48 G ATPases associated with a variety of cellular activities
MDEDNEIO_01991 2.8e-12 XK27_08585 S Hypothetical bacterial integral membrane protein (Trep_Strep)
MDEDNEIO_01992 1.2e-123 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MDEDNEIO_01993 3.1e-116 K Transcriptional regulatory protein, C terminal
MDEDNEIO_01994 3.5e-146
MDEDNEIO_01995 1.8e-148 M Putative peptidoglycan binding domain
MDEDNEIO_01996 1.3e-137 macB V ATPases associated with a variety of cellular activities
MDEDNEIO_01997 3.9e-165 V MacB-like periplasmic core domain
MDEDNEIO_01998 6.3e-296 S Psort location Cytoplasmic, score 8.87
MDEDNEIO_01999 3.3e-110 S Domain of unknown function (DUF4194)
MDEDNEIO_02000 6.9e-241 S Psort location Cytoplasmic, score 8.87
MDEDNEIO_02001 0.0 S Psort location Cytoplasmic, score 8.87
MDEDNEIO_02002 7.2e-23 S Psort location Cytoplasmic, score 8.87
MDEDNEIO_02003 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDEDNEIO_02004 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDEDNEIO_02005 1.1e-183 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
MDEDNEIO_02006 6.7e-184 rapZ S Displays ATPase and GTPase activities
MDEDNEIO_02007 1.2e-169 whiA K May be required for sporulation
MDEDNEIO_02008 1.1e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
MDEDNEIO_02009 4.2e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDEDNEIO_02010 2.5e-34 secG U Preprotein translocase SecG subunit
MDEDNEIO_02011 1.1e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MDEDNEIO_02012 8.2e-162 S Sucrose-6F-phosphate phosphohydrolase
MDEDNEIO_02013 4.8e-253 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
MDEDNEIO_02014 1.1e-216 mepA_6 V MatE
MDEDNEIO_02015 2.2e-217 brnQ U Component of the transport system for branched-chain amino acids
MDEDNEIO_02016 5.7e-200 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MDEDNEIO_02017 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
MDEDNEIO_02018 6.7e-180 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDEDNEIO_02019 9.8e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDEDNEIO_02020 1.1e-23 S Putative phage holin Dp-1
MDEDNEIO_02021 7.3e-62 M Glycosyl hydrolases family 25
MDEDNEIO_02022 1.4e-15
MDEDNEIO_02025 6.8e-57
MDEDNEIO_02026 1.2e-06 E GDSL-like Lipase/Acylhydrolase family
MDEDNEIO_02027 2.2e-210
MDEDNEIO_02028 6.2e-110
MDEDNEIO_02029 4.8e-205 S phage tail tape measure protein
MDEDNEIO_02030 4.5e-56
MDEDNEIO_02031 2.8e-125 N domain, Protein
MDEDNEIO_02032 9.7e-57
MDEDNEIO_02033 5.1e-32
MDEDNEIO_02034 6e-49
MDEDNEIO_02035 5.2e-53 S Phage protein Gp19/Gp15/Gp42
MDEDNEIO_02037 2.6e-134 V Phage capsid family
MDEDNEIO_02038 1.8e-50
MDEDNEIO_02040 1.5e-89
MDEDNEIO_02041 3.7e-192 S Phage portal protein, SPP1 Gp6-like
MDEDNEIO_02042 5.5e-219 S Terminase
MDEDNEIO_02043 1e-29
MDEDNEIO_02044 1.3e-61 L HNH endonuclease
MDEDNEIO_02047 1.4e-90 J tRNA 5'-leader removal
MDEDNEIO_02048 4e-39
MDEDNEIO_02053 0.0 T Bifunctional DNA primase/polymerase, N-terminal
MDEDNEIO_02055 8.6e-40 L single-stranded DNA binding
MDEDNEIO_02056 1.9e-165
MDEDNEIO_02058 1.3e-19
MDEDNEIO_02061 1.7e-52 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
MDEDNEIO_02066 2.6e-130 K BRO family, N-terminal domain
MDEDNEIO_02068 2e-07 S Helix-turn-helix domain
MDEDNEIO_02069 2.5e-16
MDEDNEIO_02070 5.8e-27 S IrrE N-terminal-like domain
MDEDNEIO_02071 6.5e-90 T T5orf172
MDEDNEIO_02072 1.4e-98
MDEDNEIO_02073 2.6e-22
MDEDNEIO_02074 3.2e-116 L Phage integrase family
MDEDNEIO_02075 2.4e-155 G Fructosamine kinase
MDEDNEIO_02076 1.9e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MDEDNEIO_02077 2.2e-162 S PAC2 family
MDEDNEIO_02083 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDEDNEIO_02084 3.8e-110 hit 2.7.7.53 FG HIT domain
MDEDNEIO_02085 4.5e-111 yebC K transcriptional regulatory protein
MDEDNEIO_02086 1.1e-96 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MDEDNEIO_02087 1.8e-89 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDEDNEIO_02088 6.8e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDEDNEIO_02089 5.6e-37 yajC U Preprotein translocase subunit
MDEDNEIO_02090 8.2e-89 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDEDNEIO_02091 7.1e-212 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MDEDNEIO_02092 6.9e-159 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MDEDNEIO_02093 9.9e-234
MDEDNEIO_02094 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MDEDNEIO_02095 2e-30
MDEDNEIO_02096 5.4e-162 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MDEDNEIO_02097 2.2e-142 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MDEDNEIO_02098 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
MDEDNEIO_02100 2.4e-289 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
MDEDNEIO_02101 0.0 pafB K WYL domain
MDEDNEIO_02102 5e-48
MDEDNEIO_02103 0.0 helY L DEAD DEAH box helicase
MDEDNEIO_02104 1.1e-61 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MDEDNEIO_02105 7.2e-135 pgp 3.1.3.18 S HAD-hyrolase-like
MDEDNEIO_02107 6.4e-45 ytrE_1 3.6.3.21 V ABC transporter
MDEDNEIO_02108 1.6e-22 V efflux transmembrane transporter activity
MDEDNEIO_02109 2.1e-58
MDEDNEIO_02110 3.4e-112 K helix_turn_helix, mercury resistance
MDEDNEIO_02111 1.1e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
MDEDNEIO_02112 9.7e-136 S Bacterial protein of unknown function (DUF881)
MDEDNEIO_02113 3.5e-28 sbp S Protein of unknown function (DUF1290)
MDEDNEIO_02114 2.6e-127 S Bacterial protein of unknown function (DUF881)
MDEDNEIO_02115 6e-106 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDEDNEIO_02116 4.6e-157 hisG 2.4.2.17 F ATP phosphoribosyltransferase
MDEDNEIO_02117 9.9e-42 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
MDEDNEIO_02118 2.3e-103 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
MDEDNEIO_02119 1.2e-185 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDEDNEIO_02120 5.1e-159 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MDEDNEIO_02121 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MDEDNEIO_02122 1.9e-132 S SOS response associated peptidase (SRAP)
MDEDNEIO_02123 2e-152 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MDEDNEIO_02124 3.2e-256 mmuP E amino acid
MDEDNEIO_02125 1e-23 EGP Major facilitator Superfamily
MDEDNEIO_02126 1.8e-27 EGP Major facilitator Superfamily
MDEDNEIO_02127 2.7e-42 V VanZ like family
MDEDNEIO_02128 9.6e-48 L Transposase, Mutator family
MDEDNEIO_02129 1.5e-12 L transposase and inactivated derivatives, IS30 family
MDEDNEIO_02130 2e-14 L Transposase and inactivated derivatives IS30 family
MDEDNEIO_02131 1.5e-14 L transposase and inactivated derivatives, IS30 family
MDEDNEIO_02132 4.9e-54 yxaM EGP Major facilitator Superfamily
MDEDNEIO_02133 5.7e-90 G transmembrane transporter activity
MDEDNEIO_02134 3e-90 MA20_25245 K FR47-like protein
MDEDNEIO_02135 6.4e-27 S Uncharacterized protein conserved in bacteria (DUF2316)
MDEDNEIO_02136 1.6e-99 S Acetyltransferase (GNAT) domain
MDEDNEIO_02137 3.9e-44 K Addiction module
MDEDNEIO_02138 8.6e-09 S TIGRFAM Addiction module killer protein
MDEDNEIO_02139 8.5e-50
MDEDNEIO_02140 7.1e-86 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDEDNEIO_02141 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
MDEDNEIO_02143 6.4e-256 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
MDEDNEIO_02144 5.5e-171 dppB EP Binding-protein-dependent transport system inner membrane component
MDEDNEIO_02145 6.8e-175 dppC EP Binding-protein-dependent transport system inner membrane component
MDEDNEIO_02146 1.2e-300 P Belongs to the ABC transporter superfamily
MDEDNEIO_02147 1e-164 K helix_turn _helix lactose operon repressor
MDEDNEIO_02148 4.2e-244 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
MDEDNEIO_02149 8.1e-254 S Metal-independent alpha-mannosidase (GH125)
MDEDNEIO_02150 4.3e-169 2.7.1.4 G pfkB family carbohydrate kinase
MDEDNEIO_02151 4.5e-222 GK ROK family
MDEDNEIO_02152 1.1e-161 2.7.1.2 GK ROK family
MDEDNEIO_02153 1.6e-202 GK ROK family
MDEDNEIO_02154 8.1e-151 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDEDNEIO_02155 1.1e-234 nagA 3.5.1.25 G Amidohydrolase family
MDEDNEIO_02156 2.4e-192 G Bacterial extracellular solute-binding protein
MDEDNEIO_02157 1.2e-105 U Binding-protein-dependent transport system inner membrane component
MDEDNEIO_02158 7.9e-126 G Binding-protein-dependent transport systems inner membrane component
MDEDNEIO_02160 2.7e-75 3.6.1.55 F NUDIX domain
MDEDNEIO_02161 2.8e-301 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
MDEDNEIO_02162 1.8e-160 K Psort location Cytoplasmic, score
MDEDNEIO_02163 3.2e-284 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
MDEDNEIO_02164 0.0 smc D Required for chromosome condensation and partitioning
MDEDNEIO_02165 4.9e-190 V Acetyltransferase (GNAT) domain
MDEDNEIO_02166 3.3e-294 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDEDNEIO_02167 7e-133 sigH K Belongs to the sigma-70 factor family. ECF subfamily
MDEDNEIO_02168 1.6e-54
MDEDNEIO_02169 2.8e-187 galM 5.1.3.3 G Aldose 1-epimerase
MDEDNEIO_02170 7.2e-191 galM 5.1.3.3 G Aldose 1-epimerase
MDEDNEIO_02171 5.5e-178 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MDEDNEIO_02172 1.5e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDEDNEIO_02173 4.4e-197 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDEDNEIO_02174 2.5e-135 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
MDEDNEIO_02175 2e-80 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDEDNEIO_02176 4.3e-26 rpmI J Ribosomal protein L35
MDEDNEIO_02177 1.3e-61 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDEDNEIO_02178 9.8e-169 xerD D recombinase XerD
MDEDNEIO_02179 9.5e-151 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MDEDNEIO_02180 4.7e-155 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDEDNEIO_02181 5.3e-114 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDEDNEIO_02182 4.7e-154 nrtR 3.6.1.55 F NUDIX hydrolase
MDEDNEIO_02183 2.4e-250 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MDEDNEIO_02184 9.7e-305 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MDEDNEIO_02185 8.6e-162 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
MDEDNEIO_02186 7.4e-212 iscS1 2.8.1.7 E Aminotransferase class-V
MDEDNEIO_02187 0.0 typA T Elongation factor G C-terminus
MDEDNEIO_02188 2.5e-77
MDEDNEIO_02189 1.5e-188 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
MDEDNEIO_02190 4.2e-189 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
MDEDNEIO_02191 4.5e-42
MDEDNEIO_02192 0.0 MV MacB-like periplasmic core domain
MDEDNEIO_02193 4.9e-148 V ABC transporter, ATP-binding protein
MDEDNEIO_02194 3.2e-189 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MDEDNEIO_02195 0.0 E ABC transporter, substrate-binding protein, family 5
MDEDNEIO_02196 2.2e-152 dppB EP Binding-protein-dependent transport system inner membrane component
MDEDNEIO_02197 8.7e-171 dppC EP N-terminal TM domain of oligopeptide transport permease C
MDEDNEIO_02198 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
MDEDNEIO_02199 3.1e-169 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
MDEDNEIO_02200 8.7e-148 S Protein of unknown function (DUF3710)
MDEDNEIO_02201 1.7e-126 S Protein of unknown function (DUF3159)
MDEDNEIO_02202 2.1e-238 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDEDNEIO_02203 1.6e-22 rumA 2.1.1.190 H Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDEDNEIO_02204 1.6e-73 E Glyoxalase-like domain
MDEDNEIO_02205 2.1e-49
MDEDNEIO_02206 0.0 ctpE P E1-E2 ATPase
MDEDNEIO_02207 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MDEDNEIO_02208 1.4e-57 relB L RelB antitoxin
MDEDNEIO_02209 4.7e-85 S PIN domain
MDEDNEIO_02210 1.5e-103 S Protein of unknown function DUF262
MDEDNEIO_02211 1.7e-269 S Protein of unknown function DUF262
MDEDNEIO_02212 1e-116 E Psort location Cytoplasmic, score 8.87
MDEDNEIO_02213 2e-126 ybhL S Belongs to the BI1 family
MDEDNEIO_02214 1.6e-130 ydeD EG EamA-like transporter family
MDEDNEIO_02215 1.7e-135 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
MDEDNEIO_02216 5.7e-280 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MDEDNEIO_02217 7.4e-183 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDEDNEIO_02218 1.7e-136 fic D Fic/DOC family
MDEDNEIO_02219 0.0 ftsK D FtsK SpoIIIE family protein
MDEDNEIO_02220 5.2e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDEDNEIO_02221 2.1e-91 cinA 3.5.1.42 S Belongs to the CinA family
MDEDNEIO_02222 3.6e-80 K Helix-turn-helix XRE-family like proteins
MDEDNEIO_02223 5.3e-39 S Protein of unknown function (DUF3046)
MDEDNEIO_02224 2.6e-198 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDEDNEIO_02225 2.1e-100 recX S Modulates RecA activity
MDEDNEIO_02226 4e-116 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDEDNEIO_02227 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDEDNEIO_02228 3.1e-65 E GDSL-like Lipase/Acylhydrolase family
MDEDNEIO_02229 9.7e-173 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MDEDNEIO_02230 3.2e-73
MDEDNEIO_02231 1.7e-128 plsC2 2.3.1.51 I Phosphate acyltransferases
MDEDNEIO_02232 0.0 pknL 2.7.11.1 KLT PASTA
MDEDNEIO_02233 1.8e-190 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
MDEDNEIO_02234 7.6e-123
MDEDNEIO_02235 5.8e-189 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDEDNEIO_02236 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MDEDNEIO_02237 2e-201 G Major Facilitator Superfamily
MDEDNEIO_02238 4.4e-172 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDEDNEIO_02239 0.0 lhr L DEAD DEAH box helicase
MDEDNEIO_02240 1.6e-124 KT RESPONSE REGULATOR receiver
MDEDNEIO_02241 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MDEDNEIO_02242 1.4e-234 S Type I phosphodiesterase / nucleotide pyrophosphatase
MDEDNEIO_02243 5.5e-179 S Protein of unknown function (DUF3071)
MDEDNEIO_02244 3.9e-47 S Domain of unknown function (DUF4193)
MDEDNEIO_02245 6.1e-82 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MDEDNEIO_02246 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDEDNEIO_02247 7.9e-94 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDEDNEIO_02248 2.3e-74
MDEDNEIO_02250 1.5e-252 S HipA-like C-terminal domain
MDEDNEIO_02251 3.2e-158 S Fic/DOC family
MDEDNEIO_02252 2e-110 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
MDEDNEIO_02253 4.7e-114 K WHG domain
MDEDNEIO_02255 2.1e-264 EGP Major Facilitator Superfamily
MDEDNEIO_02256 4.3e-151 L HTH-like domain
MDEDNEIO_02257 2.5e-110 L PFAM Integrase catalytic
MDEDNEIO_02258 2.7e-39 S Fic/DOC family
MDEDNEIO_02260 2.5e-49 thiF 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
MDEDNEIO_02261 1.5e-239 EGP Major facilitator Superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)