ORF_ID e_value Gene_name EC_number CAZy COGs Description
CDOLBINB_00001 1e-106 K Transcriptional regulator
CDOLBINB_00002 7.7e-116 yecA E amino acid
CDOLBINB_00010 2.6e-82 ydcK S Belongs to the SprT family
CDOLBINB_00011 0.0 yhgF K COG2183 Transcriptional accessory protein
CDOLBINB_00012 6.1e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
CDOLBINB_00013 1.5e-82 ydcG S EVE domain
CDOLBINB_00016 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
CDOLBINB_00017 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDOLBINB_00018 7.8e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
CDOLBINB_00019 1.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
CDOLBINB_00020 3.5e-188 rsbU 3.1.3.3 KT phosphatase
CDOLBINB_00021 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
CDOLBINB_00022 5.2e-57 rsbS T antagonist
CDOLBINB_00023 1.3e-143 rsbR T Positive regulator of sigma-B
CDOLBINB_00024 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
CDOLBINB_00025 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
CDOLBINB_00026 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDOLBINB_00027 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
CDOLBINB_00028 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CDOLBINB_00029 2.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
CDOLBINB_00030 1.1e-259 ydbT S Membrane
CDOLBINB_00031 2.1e-82 ydbS S Bacterial PH domain
CDOLBINB_00032 7.6e-248 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CDOLBINB_00033 4.6e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CDOLBINB_00034 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CDOLBINB_00035 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CDOLBINB_00036 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDOLBINB_00037 2.2e-07 S Fur-regulated basic protein A
CDOLBINB_00038 1.1e-18 S Fur-regulated basic protein B
CDOLBINB_00039 1.5e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
CDOLBINB_00040 2.7e-52 ydbL
CDOLBINB_00041 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CDOLBINB_00042 8e-171 ydbJ V ABC transporter, ATP-binding protein
CDOLBINB_00043 2.8e-180 ydbI S AI-2E family transporter
CDOLBINB_00044 4.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CDOLBINB_00045 3.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
CDOLBINB_00046 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CDOLBINB_00047 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
CDOLBINB_00048 7.9e-154 ydbD P Catalase
CDOLBINB_00049 1.1e-62 ydbC S Domain of unknown function (DUF4937
CDOLBINB_00050 1.3e-57 ydbB G Cupin domain
CDOLBINB_00052 1.2e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
CDOLBINB_00053 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
CDOLBINB_00055 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
CDOLBINB_00056 1.8e-38
CDOLBINB_00058 8.6e-57 ynfC
CDOLBINB_00059 2.3e-12
CDOLBINB_00060 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CDOLBINB_00061 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CDOLBINB_00062 6.6e-69 yccU S CoA-binding protein
CDOLBINB_00063 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CDOLBINB_00064 4.1e-49 yneR S Belongs to the HesB IscA family
CDOLBINB_00065 2.9e-53 yneQ
CDOLBINB_00066 1.2e-73 yneP S Thioesterase-like superfamily
CDOLBINB_00067 3.9e-35 tlp S Belongs to the Tlp family
CDOLBINB_00068 3.1e-08 sspN S Small acid-soluble spore protein N family
CDOLBINB_00070 1e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDOLBINB_00071 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CDOLBINB_00072 2.5e-14 sspO S Belongs to the SspO family
CDOLBINB_00073 3.9e-19 sspP S Belongs to the SspP family
CDOLBINB_00074 2.2e-63 hspX O Spore coat protein
CDOLBINB_00075 7.2e-74 yneK S Protein of unknown function (DUF2621)
CDOLBINB_00076 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
CDOLBINB_00077 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
CDOLBINB_00078 7.1e-127 ccdA O cytochrome c biogenesis protein
CDOLBINB_00079 4.3e-153 ywbI K Transcriptional regulator
CDOLBINB_00080 8.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CDOLBINB_00081 5.9e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CDOLBINB_00082 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
CDOLBINB_00083 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
CDOLBINB_00084 3.8e-224 ywbN P Dyp-type peroxidase family protein
CDOLBINB_00085 2.8e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
CDOLBINB_00086 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDOLBINB_00087 1.7e-48 ywcB S Protein of unknown function, DUF485
CDOLBINB_00089 1.1e-121 ywcC K transcriptional regulator
CDOLBINB_00090 1.6e-59 gtcA S GtrA-like protein
CDOLBINB_00091 1.1e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CDOLBINB_00092 8.6e-303 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
CDOLBINB_00093 1e-35 ywzA S membrane
CDOLBINB_00094 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
CDOLBINB_00095 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDOLBINB_00096 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
CDOLBINB_00097 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
CDOLBINB_00098 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
CDOLBINB_00099 2.9e-202 rodA D Belongs to the SEDS family
CDOLBINB_00100 1.2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
CDOLBINB_00101 5.2e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDOLBINB_00102 0.0 vpr O Belongs to the peptidase S8 family
CDOLBINB_00104 7e-150 sacT K transcriptional antiterminator
CDOLBINB_00105 1e-139 focA P Formate/nitrite transporter
CDOLBINB_00106 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CDOLBINB_00107 9.8e-293 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
CDOLBINB_00108 2e-28 ywdA
CDOLBINB_00109 3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CDOLBINB_00110 1.6e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
CDOLBINB_00111 4.2e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDOLBINB_00112 1.9e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
CDOLBINB_00113 7.7e-49 ywdI S Family of unknown function (DUF5327)
CDOLBINB_00114 1.1e-237 ywdJ F Xanthine uracil
CDOLBINB_00115 4.3e-59 ywdK S small membrane protein
CDOLBINB_00116 3.1e-74 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
CDOLBINB_00117 9.1e-144 spsA M Spore Coat
CDOLBINB_00118 1.2e-266 spsB M Capsule polysaccharide biosynthesis protein
CDOLBINB_00119 2.1e-224 spsC E Belongs to the DegT DnrJ EryC1 family
CDOLBINB_00120 4e-164 spsD 2.3.1.210 K Spore Coat
CDOLBINB_00121 2.7e-213 spsE 2.5.1.56 M acid synthase
CDOLBINB_00122 1.1e-127 spsF M Spore Coat
CDOLBINB_00123 6.7e-187 spsG M Spore Coat
CDOLBINB_00124 4.6e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CDOLBINB_00125 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CDOLBINB_00126 8.4e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CDOLBINB_00127 6.7e-86 spsL 5.1.3.13 M Spore Coat
CDOLBINB_00128 9.8e-77
CDOLBINB_00129 1.7e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
CDOLBINB_00130 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
CDOLBINB_00131 0.0 rocB E arginine degradation protein
CDOLBINB_00132 2e-247 lysP E amino acid
CDOLBINB_00133 2e-85 yraN K Transcriptional regulator
CDOLBINB_00134 4.4e-223 yraO C Citrate transporter
CDOLBINB_00135 8.4e-187 yrpG C Aldo/keto reductase family
CDOLBINB_00136 2.7e-94 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
CDOLBINB_00137 1.1e-93 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
CDOLBINB_00139 1.9e-124 yrpD S Domain of unknown function, YrpD
CDOLBINB_00140 1.3e-78 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CDOLBINB_00141 3e-54 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CDOLBINB_00142 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
CDOLBINB_00143 1.2e-165 aadK G Streptomycin adenylyltransferase
CDOLBINB_00144 6.4e-90 yrdA S DinB family
CDOLBINB_00145 2.6e-54 S Protein of unknown function (DUF2568)
CDOLBINB_00146 5e-99 yrdC 3.5.1.19 Q Isochorismatase family
CDOLBINB_00147 1.6e-227 cypA C Cytochrome P450
CDOLBINB_00148 6.3e-79 bkdR K helix_turn_helix ASNC type
CDOLBINB_00149 9.6e-138 azlC E AzlC protein
CDOLBINB_00150 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
CDOLBINB_00151 3.3e-226 brnQ E Component of the transport system for branched-chain amino acids
CDOLBINB_00152 7.7e-153 czcD P COG1230 Co Zn Cd efflux system component
CDOLBINB_00153 3.3e-197 trkA P Oxidoreductase
CDOLBINB_00154 3.9e-159 yrdQ K Transcriptional regulator
CDOLBINB_00155 9.2e-170 yrdR EG EamA-like transporter family
CDOLBINB_00156 8.7e-16 S YrzO-like protein
CDOLBINB_00157 4.8e-230 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CDOLBINB_00158 9.1e-83 bltD 2.3.1.57 K FR47-like protein
CDOLBINB_00159 5.1e-210 blt EGP Major facilitator Superfamily
CDOLBINB_00160 3.1e-150 bltR K helix_turn_helix, mercury resistance
CDOLBINB_00163 8.7e-19
CDOLBINB_00164 5.9e-08
CDOLBINB_00171 2.9e-29
CDOLBINB_00173 6.1e-49 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
CDOLBINB_00174 3.2e-169 S NgoFVII restriction endonuclease
CDOLBINB_00175 4.2e-23 K Transcriptional
CDOLBINB_00176 8.3e-145 dcm 2.1.1.37 L C-5 cytosine-specific DNA methylase
CDOLBINB_00179 9e-93 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CDOLBINB_00180 2.6e-28 S Agrobacterium tumefaciens protein Atu4866
CDOLBINB_00181 8.1e-91 lacR K Transcriptional regulator
CDOLBINB_00182 6.2e-102 yrkN K Acetyltransferase (GNAT) family
CDOLBINB_00183 5.3e-223 yrkO P Protein of unknown function (DUF418)
CDOLBINB_00184 4.1e-127 T Transcriptional regulator
CDOLBINB_00185 1.7e-235 yrkQ T Histidine kinase
CDOLBINB_00186 2e-68 psiE S Protein PsiE homolog
CDOLBINB_00187 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDOLBINB_00188 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
CDOLBINB_00189 2.2e-131 yqeB
CDOLBINB_00190 4.7e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
CDOLBINB_00191 2.6e-104 yqeD S SNARE associated Golgi protein
CDOLBINB_00192 1.2e-135 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CDOLBINB_00193 3.1e-141 yqeF E GDSL-like Lipase/Acylhydrolase
CDOLBINB_00195 5.3e-95 yqeG S hydrolase of the HAD superfamily
CDOLBINB_00196 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CDOLBINB_00197 6.6e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDOLBINB_00198 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
CDOLBINB_00199 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDOLBINB_00200 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
CDOLBINB_00201 2e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CDOLBINB_00202 4.2e-138 yqeM Q Methyltransferase
CDOLBINB_00203 1.9e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDOLBINB_00204 3.1e-91 wza L COG1555 DNA uptake protein and related DNA-binding proteins
CDOLBINB_00205 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
CDOLBINB_00206 0.0 comEC S Competence protein ComEC
CDOLBINB_00207 4.1e-15 S YqzM-like protein
CDOLBINB_00208 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
CDOLBINB_00209 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
CDOLBINB_00210 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CDOLBINB_00211 1.5e-222 spoIIP M stage II sporulation protein P
CDOLBINB_00212 7.2e-53 yqxA S Protein of unknown function (DUF3679)
CDOLBINB_00213 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CDOLBINB_00214 7.7e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
CDOLBINB_00215 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CDOLBINB_00216 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDOLBINB_00217 2.1e-308 dnaK O Heat shock 70 kDa protein
CDOLBINB_00218 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CDOLBINB_00219 5.4e-175 prmA J Methylates ribosomal protein L11
CDOLBINB_00220 6.1e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CDOLBINB_00221 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
CDOLBINB_00222 1.1e-156 yqeW P COG1283 Na phosphate symporter
CDOLBINB_00223 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CDOLBINB_00224 2.5e-61 yqeY S Yqey-like protein
CDOLBINB_00225 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
CDOLBINB_00226 6.1e-108 yqfA S UPF0365 protein
CDOLBINB_00227 1e-24 yqfB
CDOLBINB_00228 2.7e-45 yqfC S sporulation protein YqfC
CDOLBINB_00229 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
CDOLBINB_00230 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
CDOLBINB_00232 0.0 yqfF S membrane-associated HD superfamily hydrolase
CDOLBINB_00233 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDOLBINB_00234 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CDOLBINB_00235 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CDOLBINB_00236 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDOLBINB_00237 8.4e-19 S YqzL-like protein
CDOLBINB_00238 1.4e-144 recO L Involved in DNA repair and RecF pathway recombination
CDOLBINB_00239 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CDOLBINB_00240 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CDOLBINB_00241 4.5e-112 ccpN K CBS domain
CDOLBINB_00242 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CDOLBINB_00243 4.5e-88 yaiI S Belongs to the UPF0178 family
CDOLBINB_00244 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CDOLBINB_00245 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CDOLBINB_00246 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
CDOLBINB_00247 2.3e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
CDOLBINB_00248 1.3e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDOLBINB_00249 1.3e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDOLBINB_00250 1.9e-13 yqfQ S YqfQ-like protein
CDOLBINB_00251 6.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CDOLBINB_00252 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CDOLBINB_00253 2.1e-36 yqfT S Protein of unknown function (DUF2624)
CDOLBINB_00254 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
CDOLBINB_00255 7.1e-77 zur P Belongs to the Fur family
CDOLBINB_00256 4.6e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
CDOLBINB_00257 4.3e-62 yqfX S membrane
CDOLBINB_00258 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CDOLBINB_00259 5.8e-46 yqfZ M LysM domain
CDOLBINB_00260 8.7e-131 yqgB S Protein of unknown function (DUF1189)
CDOLBINB_00261 4e-73 yqgC S protein conserved in bacteria
CDOLBINB_00262 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
CDOLBINB_00263 5.6e-231 yqgE EGP Major facilitator superfamily
CDOLBINB_00264 0.0 pbpA 3.4.16.4 M penicillin-binding protein
CDOLBINB_00265 1.2e-150 pstS P Phosphate
CDOLBINB_00266 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
CDOLBINB_00267 4.8e-17 pstA P Phosphate transport system permease
CDOLBINB_00268 3.1e-110 pstA P Phosphate transport system permease
CDOLBINB_00269 5.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CDOLBINB_00270 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CDOLBINB_00271 7.3e-72 yqzC S YceG-like family
CDOLBINB_00272 9.2e-51 yqzD
CDOLBINB_00274 3.5e-194 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
CDOLBINB_00275 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CDOLBINB_00276 2.8e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDOLBINB_00277 2.5e-09 yqgO
CDOLBINB_00278 2.1e-237 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
CDOLBINB_00279 4.3e-33 yqgQ S Protein conserved in bacteria
CDOLBINB_00280 3.4e-180 glcK 2.7.1.2 G Glucokinase
CDOLBINB_00281 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CDOLBINB_00282 1.8e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
CDOLBINB_00283 3e-198 yqgU
CDOLBINB_00284 6.9e-50 yqgV S Thiamine-binding protein
CDOLBINB_00285 8.9e-23 yqgW S Protein of unknown function (DUF2759)
CDOLBINB_00286 1.8e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
CDOLBINB_00287 1.8e-37 yqgY S Protein of unknown function (DUF2626)
CDOLBINB_00288 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
CDOLBINB_00290 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CDOLBINB_00291 1.5e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CDOLBINB_00292 7.2e-175 corA P Mg2 transporter protein
CDOLBINB_00293 4.6e-07 ylbB S IMP dehydrogenase activity
CDOLBINB_00294 1.5e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDOLBINB_00295 1.1e-173 comGB NU COG1459 Type II secretory pathway, component PulF
CDOLBINB_00296 1.4e-47 comGC U Required for transformation and DNA binding
CDOLBINB_00297 9.5e-66 gspH NU protein transport across the cell outer membrane
CDOLBINB_00298 9e-59 comGE
CDOLBINB_00299 2e-35 comGF U Putative Competence protein ComGF
CDOLBINB_00300 1.2e-43 S ComG operon protein 7
CDOLBINB_00301 5.2e-26 yqzE S YqzE-like protein
CDOLBINB_00302 1.8e-53 yqzG S Protein of unknown function (DUF3889)
CDOLBINB_00303 6.3e-113 yqxM
CDOLBINB_00304 6.7e-59 sipW 3.4.21.89 U Signal peptidase
CDOLBINB_00305 8.6e-142 tasA S Cell division protein FtsN
CDOLBINB_00306 1e-54 sinR K transcriptional
CDOLBINB_00307 1.2e-24 sinI S Anti-repressor SinI
CDOLBINB_00308 1e-150 yqhG S Bacterial protein YqhG of unknown function
CDOLBINB_00309 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
CDOLBINB_00310 3.7e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
CDOLBINB_00311 4.9e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDOLBINB_00312 2e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDOLBINB_00313 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
CDOLBINB_00314 3.7e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
CDOLBINB_00315 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
CDOLBINB_00316 6.9e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
CDOLBINB_00317 2.2e-61 yqhP
CDOLBINB_00318 8e-174 yqhQ S Protein of unknown function (DUF1385)
CDOLBINB_00319 2.3e-93 yqhR S Conserved membrane protein YqhR
CDOLBINB_00320 4.2e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
CDOLBINB_00321 5.7e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
CDOLBINB_00322 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDOLBINB_00323 7.9e-37 yqhV S Protein of unknown function (DUF2619)
CDOLBINB_00324 4e-170 spoIIIAA S stage III sporulation protein AA
CDOLBINB_00325 1.1e-84 spoIIIAB S Stage III sporulation protein
CDOLBINB_00326 7.6e-29 spoIIIAC S stage III sporulation protein AC
CDOLBINB_00327 2.3e-58 spoIIIAD S Stage III sporulation protein AD
CDOLBINB_00328 1.7e-197 spoIIIAE S stage III sporulation protein AE
CDOLBINB_00329 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
CDOLBINB_00330 6.9e-103 spoIIIAG S stage III sporulation protein AG
CDOLBINB_00331 9.9e-91 spoIIIAH S SpoIIIAH-like protein
CDOLBINB_00332 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CDOLBINB_00333 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CDOLBINB_00334 2.1e-67 yqhY S protein conserved in bacteria
CDOLBINB_00335 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDOLBINB_00336 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDOLBINB_00337 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CDOLBINB_00338 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CDOLBINB_00339 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CDOLBINB_00340 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDOLBINB_00341 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
CDOLBINB_00342 1.9e-77 argR K Regulates arginine biosynthesis genes
CDOLBINB_00343 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
CDOLBINB_00344 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
CDOLBINB_00346 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
CDOLBINB_00348 1.8e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
CDOLBINB_00349 5.9e-27
CDOLBINB_00350 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
CDOLBINB_00351 6.4e-131 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CDOLBINB_00352 2.2e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
CDOLBINB_00353 1.3e-154 hbdA 1.1.1.157 I Dehydrogenase
CDOLBINB_00354 2e-211 mmgC I acyl-CoA dehydrogenase
CDOLBINB_00355 3.2e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
CDOLBINB_00356 1.7e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
CDOLBINB_00357 6.6e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CDOLBINB_00358 4e-34 yqzF S Protein of unknown function (DUF2627)
CDOLBINB_00359 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
CDOLBINB_00360 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
CDOLBINB_00361 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
CDOLBINB_00362 6e-202 buk 2.7.2.7 C Belongs to the acetokinase family
CDOLBINB_00363 4.9e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CDOLBINB_00364 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CDOLBINB_00365 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CDOLBINB_00366 3.2e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CDOLBINB_00367 2.4e-150 bmrR K helix_turn_helix, mercury resistance
CDOLBINB_00368 7.9e-208 norA EGP Major facilitator Superfamily
CDOLBINB_00369 2.8e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CDOLBINB_00370 9.3e-77 yqiW S Belongs to the UPF0403 family
CDOLBINB_00371 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
CDOLBINB_00372 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
CDOLBINB_00373 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CDOLBINB_00374 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
CDOLBINB_00375 1.4e-98 yqjB S protein conserved in bacteria
CDOLBINB_00377 1.9e-71 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
CDOLBINB_00378 5.5e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CDOLBINB_00379 2.4e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
CDOLBINB_00380 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
CDOLBINB_00381 7.5e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CDOLBINB_00382 1e-23 yqzJ
CDOLBINB_00383 3.8e-232 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDOLBINB_00384 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CDOLBINB_00385 2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CDOLBINB_00386 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CDOLBINB_00387 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CDOLBINB_00388 1.8e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CDOLBINB_00389 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
CDOLBINB_00390 0.0 rocB E arginine degradation protein
CDOLBINB_00391 3.3e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDOLBINB_00392 4.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
CDOLBINB_00393 2.9e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
CDOLBINB_00394 5.4e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
CDOLBINB_00395 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
CDOLBINB_00396 4.6e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CDOLBINB_00398 1.9e-223 yqjV G Major Facilitator Superfamily
CDOLBINB_00400 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDOLBINB_00401 2.2e-49 S YolD-like protein
CDOLBINB_00402 5.3e-86 yqjY K acetyltransferase
CDOLBINB_00403 1.5e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
CDOLBINB_00404 2.7e-191 yqkA K GrpB protein
CDOLBINB_00405 3.7e-54 yqkB S Belongs to the HesB IscA family
CDOLBINB_00406 9.4e-39 yqkC S Protein of unknown function (DUF2552)
CDOLBINB_00407 1.4e-170 yqkD S COG1073 Hydrolases of the alpha beta superfamily
CDOLBINB_00408 3.1e-12 yqkE S Protein of unknown function (DUF3886)
CDOLBINB_00409 9.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
CDOLBINB_00411 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
CDOLBINB_00412 4.9e-218 yqxK 3.6.4.12 L DNA helicase
CDOLBINB_00413 4.5e-58 ansR K Transcriptional regulator
CDOLBINB_00414 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
CDOLBINB_00415 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
CDOLBINB_00416 9.1e-235 mleN C Na H antiporter
CDOLBINB_00417 1.2e-241 mleA 1.1.1.38 C malic enzyme
CDOLBINB_00418 1.3e-89 thiT S Thiamine transporter protein (Thia_YuaJ)
CDOLBINB_00419 5.5e-92 M1-753 M FR47-like protein
CDOLBINB_00420 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
CDOLBINB_00421 1.9e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
CDOLBINB_00422 3.9e-84 yuaE S DinB superfamily
CDOLBINB_00423 1.1e-106 yuaD
CDOLBINB_00424 3.2e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
CDOLBINB_00425 1.3e-279 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
CDOLBINB_00426 6.7e-93 yuaC K Belongs to the GbsR family
CDOLBINB_00427 2.2e-91 yuaB
CDOLBINB_00428 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
CDOLBINB_00429 7.9e-236 ktrB P Potassium
CDOLBINB_00430 1e-38 yiaA S yiaA/B two helix domain
CDOLBINB_00431 1.9e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CDOLBINB_00432 1.3e-274 yubD P Major Facilitator Superfamily
CDOLBINB_00433 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
CDOLBINB_00435 5.9e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CDOLBINB_00436 9.1e-196 yubA S transporter activity
CDOLBINB_00437 9.7e-183 ygjR S Oxidoreductase
CDOLBINB_00438 9.7e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
CDOLBINB_00439 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
CDOLBINB_00440 6.7e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
CDOLBINB_00441 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
CDOLBINB_00442 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
CDOLBINB_00443 1.1e-238 mcpA NT chemotaxis protein
CDOLBINB_00444 8.5e-295 mcpA NT chemotaxis protein
CDOLBINB_00445 1.5e-219 mcpA NT chemotaxis protein
CDOLBINB_00446 3.2e-225 mcpA NT chemotaxis protein
CDOLBINB_00447 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
CDOLBINB_00448 1e-35
CDOLBINB_00449 2.1e-72 yugU S Uncharacterised protein family UPF0047
CDOLBINB_00450 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
CDOLBINB_00451 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
CDOLBINB_00452 1.4e-116 yugP S Zn-dependent protease
CDOLBINB_00453 7.4e-37
CDOLBINB_00454 1.1e-53 mstX S Membrane-integrating protein Mistic
CDOLBINB_00455 1.7e-182 yugO P COG1226 Kef-type K transport systems
CDOLBINB_00456 1.3e-72 yugN S YugN-like family
CDOLBINB_00458 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
CDOLBINB_00459 1.1e-228 yugK C Dehydrogenase
CDOLBINB_00460 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
CDOLBINB_00461 1.1e-34 yuzA S Domain of unknown function (DUF378)
CDOLBINB_00462 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
CDOLBINB_00463 4.8e-199 yugH 2.6.1.1 E Aminotransferase
CDOLBINB_00464 1.6e-85 alaR K Transcriptional regulator
CDOLBINB_00465 4.2e-155 yugF I Hydrolase
CDOLBINB_00466 1.1e-40 yugE S Domain of unknown function (DUF1871)
CDOLBINB_00467 1.7e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CDOLBINB_00468 2.1e-230 T PhoQ Sensor
CDOLBINB_00469 7.4e-70 kapB G Kinase associated protein B
CDOLBINB_00470 4.2e-115 kapD L the KinA pathway to sporulation
CDOLBINB_00472 4.2e-184 yuxJ EGP Major facilitator Superfamily
CDOLBINB_00473 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
CDOLBINB_00474 6.9e-74 yuxK S protein conserved in bacteria
CDOLBINB_00475 6.3e-78 yufK S Family of unknown function (DUF5366)
CDOLBINB_00476 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CDOLBINB_00477 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
CDOLBINB_00478 4.2e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
CDOLBINB_00479 2.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
CDOLBINB_00480 9.3e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
CDOLBINB_00481 3.3e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
CDOLBINB_00482 8.2e-233 maeN C COG3493 Na citrate symporter
CDOLBINB_00483 5e-15
CDOLBINB_00484 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CDOLBINB_00485 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CDOLBINB_00486 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CDOLBINB_00487 7.1e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CDOLBINB_00488 3.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CDOLBINB_00489 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CDOLBINB_00490 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
CDOLBINB_00491 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
CDOLBINB_00492 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CDOLBINB_00493 3.6e-280 comP 2.7.13.3 T Histidine kinase
CDOLBINB_00494 3.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
CDOLBINB_00495 4.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CDOLBINB_00496 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
CDOLBINB_00497 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDOLBINB_00498 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
CDOLBINB_00499 1.2e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
CDOLBINB_00500 1.5e-166 ctaG S cytochrome c oxidase
CDOLBINB_00501 7e-62 ylbA S YugN-like family
CDOLBINB_00502 2.6e-74 ylbB T COG0517 FOG CBS domain
CDOLBINB_00503 9.6e-200 ylbC S protein with SCP PR1 domains
CDOLBINB_00504 2.6e-62 ylbD S Putative coat protein
CDOLBINB_00505 6.7e-37 ylbE S YlbE-like protein
CDOLBINB_00506 1.8e-75 ylbF S Belongs to the UPF0342 family
CDOLBINB_00507 7.5e-39 ylbG S UPF0298 protein
CDOLBINB_00508 5.4e-98 rsmD 2.1.1.171 L Methyltransferase
CDOLBINB_00509 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDOLBINB_00510 9.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
CDOLBINB_00511 1.3e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
CDOLBINB_00512 6.8e-187 ylbL T Belongs to the peptidase S16 family
CDOLBINB_00513 4.9e-232 ylbM S Belongs to the UPF0348 family
CDOLBINB_00515 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
CDOLBINB_00516 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CDOLBINB_00517 9.7e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
CDOLBINB_00518 1.5e-88 ylbP K n-acetyltransferase
CDOLBINB_00519 2.8e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CDOLBINB_00520 8.7e-306 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CDOLBINB_00521 2.9e-78 mraZ K Belongs to the MraZ family
CDOLBINB_00522 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CDOLBINB_00523 3.7e-44 ftsL D Essential cell division protein
CDOLBINB_00524 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
CDOLBINB_00525 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
CDOLBINB_00526 8.9e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDOLBINB_00527 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDOLBINB_00528 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDOLBINB_00529 5.7e-186 spoVE D Belongs to the SEDS family
CDOLBINB_00530 2.5e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDOLBINB_00531 5.3e-167 murB 1.3.1.98 M cell wall formation
CDOLBINB_00532 7.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CDOLBINB_00533 2.4e-103 ylxW S protein conserved in bacteria
CDOLBINB_00534 1.8e-91 ylxX S protein conserved in bacteria
CDOLBINB_00535 6.2e-58 sbp S small basic protein
CDOLBINB_00536 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CDOLBINB_00537 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDOLBINB_00538 0.0 bpr O COG1404 Subtilisin-like serine proteases
CDOLBINB_00539 1.7e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
CDOLBINB_00540 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDOLBINB_00541 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDOLBINB_00542 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
CDOLBINB_00543 2e-252 argE 3.5.1.16 E Acetylornithine deacetylase
CDOLBINB_00544 2.4e-37 ylmC S sporulation protein
CDOLBINB_00545 1.7e-156 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
CDOLBINB_00546 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CDOLBINB_00547 6.7e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CDOLBINB_00548 1.6e-39 yggT S membrane
CDOLBINB_00549 7.5e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
CDOLBINB_00550 2.6e-67 divIVA D Cell division initiation protein
CDOLBINB_00551 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDOLBINB_00552 8.5e-63 dksA T COG1734 DnaK suppressor protein
CDOLBINB_00553 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDOLBINB_00554 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CDOLBINB_00555 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CDOLBINB_00556 2.6e-231 pyrP F Xanthine uracil
CDOLBINB_00557 1.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CDOLBINB_00558 6.4e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CDOLBINB_00559 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CDOLBINB_00560 0.0 carB 6.3.5.5 F Belongs to the CarB family
CDOLBINB_00561 5.9e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CDOLBINB_00562 1e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CDOLBINB_00563 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CDOLBINB_00564 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CDOLBINB_00565 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
CDOLBINB_00566 1.8e-179 cysP P phosphate transporter
CDOLBINB_00567 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
CDOLBINB_00568 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
CDOLBINB_00569 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
CDOLBINB_00570 1.2e-143 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
CDOLBINB_00571 3.7e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
CDOLBINB_00572 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
CDOLBINB_00573 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
CDOLBINB_00574 2.4e-156 yloC S stress-induced protein
CDOLBINB_00575 1.5e-40 ylzA S Belongs to the UPF0296 family
CDOLBINB_00576 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CDOLBINB_00577 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CDOLBINB_00578 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDOLBINB_00579 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDOLBINB_00580 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CDOLBINB_00581 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDOLBINB_00582 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDOLBINB_00583 3.4e-205 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CDOLBINB_00584 1.6e-140 stp 3.1.3.16 T phosphatase
CDOLBINB_00585 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
CDOLBINB_00586 2.1e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CDOLBINB_00587 9.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CDOLBINB_00588 8.4e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
CDOLBINB_00589 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CDOLBINB_00590 5.5e-59 asp S protein conserved in bacteria
CDOLBINB_00591 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
CDOLBINB_00592 5.6e-118 sdaAB 4.3.1.17 E L-serine dehydratase
CDOLBINB_00593 1.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
CDOLBINB_00594 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDOLBINB_00595 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
CDOLBINB_00596 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CDOLBINB_00597 3.8e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CDOLBINB_00598 2.5e-127 IQ reductase
CDOLBINB_00599 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDOLBINB_00600 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CDOLBINB_00601 0.0 smc D Required for chromosome condensation and partitioning
CDOLBINB_00602 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CDOLBINB_00603 2.9e-87
CDOLBINB_00604 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CDOLBINB_00605 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDOLBINB_00606 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CDOLBINB_00607 4.5e-36 ylqC S Belongs to the UPF0109 family
CDOLBINB_00608 6.3e-61 ylqD S YlqD protein
CDOLBINB_00609 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDOLBINB_00610 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CDOLBINB_00611 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CDOLBINB_00612 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CDOLBINB_00613 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDOLBINB_00614 3e-288 ylqG
CDOLBINB_00615 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
CDOLBINB_00616 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
CDOLBINB_00617 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CDOLBINB_00618 4.7e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
CDOLBINB_00619 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDOLBINB_00620 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CDOLBINB_00621 9.7e-169 xerC L tyrosine recombinase XerC
CDOLBINB_00622 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CDOLBINB_00623 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CDOLBINB_00624 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CDOLBINB_00625 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
CDOLBINB_00626 3.4e-74 flgC N Belongs to the flagella basal body rod proteins family
CDOLBINB_00627 1.9e-31 fliE N Flagellar hook-basal body
CDOLBINB_00628 7e-255 fliF N The M ring may be actively involved in energy transduction
CDOLBINB_00629 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CDOLBINB_00630 9.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
CDOLBINB_00631 2.1e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
CDOLBINB_00632 1.5e-69 fliJ N Flagellar biosynthesis chaperone
CDOLBINB_00633 5.5e-35 ylxF S MgtE intracellular N domain
CDOLBINB_00634 4.7e-210 fliK N Flagellar hook-length control protein
CDOLBINB_00635 1.7e-72 flgD N Flagellar basal body rod modification protein
CDOLBINB_00636 8.2e-140 flgG N Flagellar basal body rod
CDOLBINB_00637 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
CDOLBINB_00638 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CDOLBINB_00639 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDOLBINB_00640 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
CDOLBINB_00641 6.7e-95 fliZ N Flagellar biosynthesis protein, FliO
CDOLBINB_00642 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
CDOLBINB_00643 2.2e-36 fliQ N Role in flagellar biosynthesis
CDOLBINB_00644 3.6e-132 fliR N Flagellar biosynthetic protein FliR
CDOLBINB_00645 4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDOLBINB_00646 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDOLBINB_00647 6.8e-201 flhF N Flagellar biosynthesis regulator FlhF
CDOLBINB_00648 3.7e-157 flhG D Belongs to the ParA family
CDOLBINB_00649 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
CDOLBINB_00650 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
CDOLBINB_00651 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
CDOLBINB_00652 2.8e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
CDOLBINB_00653 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
CDOLBINB_00654 7.4e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDOLBINB_00655 4.8e-77 ylxL
CDOLBINB_00656 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
CDOLBINB_00657 1.8e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDOLBINB_00658 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CDOLBINB_00659 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CDOLBINB_00660 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDOLBINB_00661 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
CDOLBINB_00662 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
CDOLBINB_00663 7.7e-233 rasP M zinc metalloprotease
CDOLBINB_00664 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CDOLBINB_00665 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDOLBINB_00666 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
CDOLBINB_00667 1.1e-203 nusA K Participates in both transcription termination and antitermination
CDOLBINB_00668 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
CDOLBINB_00669 3.1e-47 ylxQ J ribosomal protein
CDOLBINB_00670 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CDOLBINB_00671 3.9e-44 ylxP S protein conserved in bacteria
CDOLBINB_00672 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDOLBINB_00673 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDOLBINB_00674 1.5e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CDOLBINB_00675 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDOLBINB_00676 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CDOLBINB_00677 1e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
CDOLBINB_00678 4.4e-233 pepR S Belongs to the peptidase M16 family
CDOLBINB_00679 2.6e-42 ymxH S YlmC YmxH family
CDOLBINB_00680 6.6e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
CDOLBINB_00681 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
CDOLBINB_00682 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDOLBINB_00683 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
CDOLBINB_00684 8.9e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDOLBINB_00685 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CDOLBINB_00686 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
CDOLBINB_00687 4.4e-32 S YlzJ-like protein
CDOLBINB_00688 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CDOLBINB_00689 1.4e-133 ymfC K Transcriptional regulator
CDOLBINB_00690 3.8e-205 ymfD EGP Major facilitator Superfamily
CDOLBINB_00691 3e-232 ymfF S Peptidase M16
CDOLBINB_00692 2.4e-242 ymfH S zinc protease
CDOLBINB_00693 1.7e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
CDOLBINB_00694 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
CDOLBINB_00695 2.7e-143 ymfK S Protein of unknown function (DUF3388)
CDOLBINB_00696 1.9e-124 ymfM S protein conserved in bacteria
CDOLBINB_00697 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDOLBINB_00698 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
CDOLBINB_00699 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDOLBINB_00700 8.2e-213 pbpX V Beta-lactamase
CDOLBINB_00701 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
CDOLBINB_00702 1.9e-152 ymdB S protein conserved in bacteria
CDOLBINB_00703 1.2e-36 spoVS S Stage V sporulation protein S
CDOLBINB_00704 4.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
CDOLBINB_00705 1.4e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CDOLBINB_00706 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDOLBINB_00707 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
CDOLBINB_00708 2.2e-88 cotE S Spore coat protein
CDOLBINB_00709 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CDOLBINB_00710 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDOLBINB_00711 3.1e-70 S Regulatory protein YrvL
CDOLBINB_00712 1.8e-96 ymcC S Membrane
CDOLBINB_00713 2.2e-108 pksA K Transcriptional regulator
CDOLBINB_00714 3.7e-125 pksB 3.1.2.6 S Polyketide biosynthesis
CDOLBINB_00715 1.2e-160 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CDOLBINB_00717 1.6e-182 pksD Q Acyl transferase domain
CDOLBINB_00718 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CDOLBINB_00719 1.4e-37 acpK IQ Phosphopantetheine attachment site
CDOLBINB_00720 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CDOLBINB_00721 1.3e-245 pksG 2.3.3.10 I synthase
CDOLBINB_00722 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
CDOLBINB_00723 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
CDOLBINB_00724 0.0 rhiB IQ polyketide synthase
CDOLBINB_00725 0.0 pfaA Q Polyketide synthase of type I
CDOLBINB_00726 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
CDOLBINB_00727 0.0 dhbF IQ polyketide synthase
CDOLBINB_00728 0.0 pks13 HQ Beta-ketoacyl synthase
CDOLBINB_00729 2.4e-231 cypA C Cytochrome P450
CDOLBINB_00730 4.4e-61 ymzB
CDOLBINB_00731 1.2e-160 ymaE S Metallo-beta-lactamase superfamily
CDOLBINB_00732 3e-251 aprX O Belongs to the peptidase S8 family
CDOLBINB_00733 1.9e-07 K Transcriptional regulator
CDOLBINB_00734 2.1e-126 ymaC S Replication protein
CDOLBINB_00735 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
CDOLBINB_00736 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
CDOLBINB_00737 5.4e-50 ebrA P Small Multidrug Resistance protein
CDOLBINB_00739 2.1e-46 ymaF S YmaF family
CDOLBINB_00740 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDOLBINB_00741 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
CDOLBINB_00742 8.2e-23
CDOLBINB_00743 4.5e-22 ymzA
CDOLBINB_00744 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
CDOLBINB_00745 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDOLBINB_00746 5e-187 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDOLBINB_00747 3.4e-109 ymaB
CDOLBINB_00748 2.8e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CDOLBINB_00749 1.7e-176 spoVK O stage V sporulation protein K
CDOLBINB_00750 2.3e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDOLBINB_00751 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
CDOLBINB_00752 4.3e-68 glnR K transcriptional
CDOLBINB_00753 7e-261 glnA 6.3.1.2 E glutamine synthetase
CDOLBINB_00754 1.1e-09
CDOLBINB_00755 5.6e-30
CDOLBINB_00756 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CDOLBINB_00757 4.6e-70 3.4.13.21 S ASCH
CDOLBINB_00758 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
CDOLBINB_00759 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
CDOLBINB_00760 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDOLBINB_00761 1.5e-229 yhgE S YhgE Pip N-terminal domain protein
CDOLBINB_00762 5.4e-101 yhgD K Transcriptional regulator
CDOLBINB_00763 4.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CDOLBINB_00764 6.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
CDOLBINB_00765 9.1e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDOLBINB_00766 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CDOLBINB_00767 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
CDOLBINB_00768 1.1e-31 1.15.1.2 C Rubrerythrin
CDOLBINB_00769 4.2e-240 yhfA C membrane
CDOLBINB_00770 8.3e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CDOLBINB_00771 6.9e-114 ecsC S EcsC protein family
CDOLBINB_00772 5.9e-214 ecsB U ABC transporter
CDOLBINB_00773 4.6e-137 ecsA V transporter (ATP-binding protein)
CDOLBINB_00774 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CDOLBINB_00775 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CDOLBINB_00776 3.6e-80 trpP S Tryptophan transporter TrpP
CDOLBINB_00777 5.4e-21
CDOLBINB_00778 8.2e-39 yhaH S YtxH-like protein
CDOLBINB_00779 1e-113 hpr K Negative regulator of protease production and sporulation
CDOLBINB_00780 1.3e-54 yhaI S Protein of unknown function (DUF1878)
CDOLBINB_00781 4.3e-89 yhaK S Putative zincin peptidase
CDOLBINB_00782 1.8e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CDOLBINB_00783 1.6e-21 yhaL S Sporulation protein YhaL
CDOLBINB_00784 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
CDOLBINB_00785 0.0 yhaN L AAA domain
CDOLBINB_00786 2.6e-225 yhaO L DNA repair exonuclease
CDOLBINB_00787 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
CDOLBINB_00788 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
CDOLBINB_00789 1.8e-55
CDOLBINB_00790 0.0 M Domain of unknown function DUF11
CDOLBINB_00791 3e-75 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
CDOLBINB_00794 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CDOLBINB_00795 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDOLBINB_00796 4.1e-30 yazB K transcriptional
CDOLBINB_00797 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDOLBINB_00798 2.9e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDOLBINB_00799 3.8e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDOLBINB_00800 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
CDOLBINB_00801 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
CDOLBINB_00802 4.1e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDOLBINB_00803 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CDOLBINB_00804 1.4e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
CDOLBINB_00805 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDOLBINB_00806 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CDOLBINB_00807 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDOLBINB_00808 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CDOLBINB_00809 1e-270 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CDOLBINB_00810 9.7e-186 KLT serine threonine protein kinase
CDOLBINB_00811 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
CDOLBINB_00812 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
CDOLBINB_00815 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
CDOLBINB_00816 1.1e-44 divIC D Septum formation initiator
CDOLBINB_00817 9.5e-107 yabQ S spore cortex biosynthesis protein
CDOLBINB_00818 1.5e-49 yabP S Sporulation protein YabP
CDOLBINB_00819 2.5e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CDOLBINB_00820 1.6e-242 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
CDOLBINB_00821 1.6e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CDOLBINB_00822 1.5e-92 spoVT K stage V sporulation protein
CDOLBINB_00823 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDOLBINB_00824 2.4e-39 yabK S Peptide ABC transporter permease
CDOLBINB_00825 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CDOLBINB_00826 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CDOLBINB_00827 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDOLBINB_00828 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDOLBINB_00829 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
CDOLBINB_00830 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
CDOLBINB_00831 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
CDOLBINB_00832 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDOLBINB_00833 8.3e-27 sspF S DNA topological change
CDOLBINB_00834 7.8e-39 veg S protein conserved in bacteria
CDOLBINB_00835 1.6e-136 yabG S peptidase
CDOLBINB_00836 6.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CDOLBINB_00837 1e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CDOLBINB_00838 2e-167 rpfB GH23 T protein conserved in bacteria
CDOLBINB_00839 1.2e-143 tatD L hydrolase, TatD
CDOLBINB_00840 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDOLBINB_00841 1.1e-191 yceA S Belongs to the UPF0176 family
CDOLBINB_00842 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CDOLBINB_00843 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CDOLBINB_00844 1.2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CDOLBINB_00845 1.2e-126 K UTRA
CDOLBINB_00847 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CDOLBINB_00848 6.7e-262 mmuP E amino acid
CDOLBINB_00849 3e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
CDOLBINB_00850 2.5e-256 agcS E Sodium alanine symporter
CDOLBINB_00851 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
CDOLBINB_00852 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
CDOLBINB_00853 1.5e-169 glnL T Regulator
CDOLBINB_00854 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
CDOLBINB_00855 1e-271 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CDOLBINB_00856 5e-254 gudP G COG0477 Permeases of the major facilitator superfamily
CDOLBINB_00857 3e-267 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
CDOLBINB_00858 1.5e-124 ycbG K FCD
CDOLBINB_00859 1.3e-295 garD 4.2.1.42, 4.2.1.7 G Altronate
CDOLBINB_00860 1.2e-174 ycbJ S Macrolide 2'-phosphotransferase
CDOLBINB_00861 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
CDOLBINB_00862 1.5e-169 eamA1 EG spore germination
CDOLBINB_00863 7.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CDOLBINB_00864 4.9e-168 T PhoQ Sensor
CDOLBINB_00865 1.2e-163 ycbN V ABC transporter, ATP-binding protein
CDOLBINB_00866 1.5e-113 S ABC-2 family transporter protein
CDOLBINB_00867 8.2e-53 ycbP S Protein of unknown function (DUF2512)
CDOLBINB_00868 2.2e-78 sleB 3.5.1.28 M Cell wall
CDOLBINB_00869 2.5e-135 ycbR T vWA found in TerF C terminus
CDOLBINB_00870 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
CDOLBINB_00871 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CDOLBINB_00872 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDOLBINB_00873 2e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CDOLBINB_00874 2.7e-205 ycbU E Selenocysteine lyase
CDOLBINB_00875 7.9e-226 lmrB EGP the major facilitator superfamily
CDOLBINB_00876 3.1e-101 yxaF K Transcriptional regulator
CDOLBINB_00877 2.6e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CDOLBINB_00878 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
CDOLBINB_00879 1.6e-56 S RDD family
CDOLBINB_00880 1.4e-198 yccF K DNA-templated transcriptional preinitiation complex assembly
CDOLBINB_00881 2e-156 2.7.13.3 T GHKL domain
CDOLBINB_00882 1.2e-126 lytR_2 T LytTr DNA-binding domain
CDOLBINB_00883 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
CDOLBINB_00884 1.2e-200 natB CP ABC-2 family transporter protein
CDOLBINB_00885 5e-173 yccK C Aldo keto reductase
CDOLBINB_00886 6.6e-177 ycdA S Domain of unknown function (DUF5105)
CDOLBINB_00887 7e-275 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
CDOLBINB_00888 2.4e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
CDOLBINB_00889 1.3e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
CDOLBINB_00890 6.1e-173 S response regulator aspartate phosphatase
CDOLBINB_00891 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
CDOLBINB_00892 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
CDOLBINB_00893 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
CDOLBINB_00894 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CDOLBINB_00895 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CDOLBINB_00896 4.7e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDOLBINB_00897 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
CDOLBINB_00898 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
CDOLBINB_00899 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
CDOLBINB_00900 3.1e-136 terC P Protein of unknown function (DUF475)
CDOLBINB_00901 0.0 yceG S Putative component of 'biosynthetic module'
CDOLBINB_00902 4.4e-192 yceH P Belongs to the TelA family
CDOLBINB_00903 6.6e-218 naiP P Uncharacterised MFS-type transporter YbfB
CDOLBINB_00904 4.1e-204 yceJ EGP Uncharacterised MFS-type transporter YbfB
CDOLBINB_00905 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
CDOLBINB_00906 5.1e-229 proV 3.6.3.32 E glycine betaine
CDOLBINB_00907 1.3e-127 opuAB P glycine betaine
CDOLBINB_00908 5.3e-164 opuAC E glycine betaine
CDOLBINB_00909 9.2e-217 amhX S amidohydrolase
CDOLBINB_00910 6.6e-182 ycgA S Membrane
CDOLBINB_00911 1.2e-63 ycgA S Membrane
CDOLBINB_00912 7e-81 ycgB
CDOLBINB_00913 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
CDOLBINB_00914 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CDOLBINB_00915 7.2e-292 lctP C L-lactate permease
CDOLBINB_00916 3.6e-261 mdr EGP Major facilitator Superfamily
CDOLBINB_00917 1.3e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
CDOLBINB_00918 6.8e-113 ycgF E Lysine exporter protein LysE YggA
CDOLBINB_00919 4.9e-150 yqcI S YqcI/YcgG family
CDOLBINB_00920 6.2e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
CDOLBINB_00921 2.4e-112 ycgI S Domain of unknown function (DUF1989)
CDOLBINB_00922 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CDOLBINB_00923 1.1e-107 tmrB S AAA domain
CDOLBINB_00924 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDOLBINB_00925 9e-144 yafE Q ubiE/COQ5 methyltransferase family
CDOLBINB_00926 3.1e-173 oxyR3 K LysR substrate binding domain
CDOLBINB_00927 4.2e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
CDOLBINB_00928 1.9e-144 ycgL S Predicted nucleotidyltransferase
CDOLBINB_00929 5.1e-170 ycgM E Proline dehydrogenase
CDOLBINB_00930 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
CDOLBINB_00931 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDOLBINB_00932 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
CDOLBINB_00933 7.5e-147 ycgQ S membrane
CDOLBINB_00934 1.2e-139 ycgR S permeases
CDOLBINB_00935 3.8e-159 I alpha/beta hydrolase fold
CDOLBINB_00936 8.4e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
CDOLBINB_00937 6e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
CDOLBINB_00938 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
CDOLBINB_00939 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDOLBINB_00940 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CDOLBINB_00941 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
CDOLBINB_00942 4.9e-221 nasA P COG2223 Nitrate nitrite transporter
CDOLBINB_00943 2.1e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
CDOLBINB_00944 8.5e-23 yciB M ErfK YbiS YcfS YnhG
CDOLBINB_00945 1.5e-67 yciB M ErfK YbiS YcfS YnhG
CDOLBINB_00946 2e-227 yciC S GTPases (G3E family)
CDOLBINB_00947 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
CDOLBINB_00948 4e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
CDOLBINB_00950 5.3e-75 yckC S membrane
CDOLBINB_00951 3.9e-51 yckD S Protein of unknown function (DUF2680)
CDOLBINB_00952 7.2e-296 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CDOLBINB_00953 1.7e-69 nin S Competence protein J (ComJ)
CDOLBINB_00954 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
CDOLBINB_00955 1.8e-184 tlpC 2.7.13.3 NT chemotaxis protein
CDOLBINB_00956 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
CDOLBINB_00957 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
CDOLBINB_00958 1.3e-63 hxlR K transcriptional
CDOLBINB_00959 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CDOLBINB_00960 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
CDOLBINB_00961 3.7e-139 srfAD Q thioesterase
CDOLBINB_00962 1.8e-226 EGP Major Facilitator Superfamily
CDOLBINB_00963 1.1e-85 S YcxB-like protein
CDOLBINB_00964 2.9e-160 ycxC EG EamA-like transporter family
CDOLBINB_00965 1.5e-250 ycxD K GntR family transcriptional regulator
CDOLBINB_00966 2.3e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
CDOLBINB_00967 1.7e-114 yczE S membrane
CDOLBINB_00968 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CDOLBINB_00969 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
CDOLBINB_00970 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
CDOLBINB_00971 1.2e-160 bsdA K LysR substrate binding domain
CDOLBINB_00972 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
CDOLBINB_00973 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
CDOLBINB_00974 4e-39 bsdD 4.1.1.61 S response to toxic substance
CDOLBINB_00975 3.5e-82 yclD
CDOLBINB_00976 3.3e-155 yclE 3.4.11.5 S Alpha beta hydrolase
CDOLBINB_00977 5.2e-265 dtpT E amino acid peptide transporter
CDOLBINB_00978 2.5e-298 yclG M Pectate lyase superfamily protein
CDOLBINB_00980 7e-279 gerKA EG Spore germination protein
CDOLBINB_00981 2.8e-224 gerKC S spore germination
CDOLBINB_00982 1.4e-193 gerKB F Spore germination protein
CDOLBINB_00983 2.8e-120 yclH P ABC transporter
CDOLBINB_00984 7.6e-200 yclI V ABC transporter (permease) YclI
CDOLBINB_00985 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CDOLBINB_00986 4.4e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
CDOLBINB_00987 2e-70 S aspartate phosphatase
CDOLBINB_00991 1.7e-238 lysC 2.7.2.4 E Belongs to the aspartokinase family
CDOLBINB_00992 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDOLBINB_00993 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDOLBINB_00994 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
CDOLBINB_00995 3.2e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
CDOLBINB_00996 3.2e-251 ycnB EGP Major facilitator Superfamily
CDOLBINB_00997 6.5e-154 ycnC K Transcriptional regulator
CDOLBINB_00998 9.8e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
CDOLBINB_00999 1.6e-45 ycnE S Monooxygenase
CDOLBINB_01000 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
CDOLBINB_01001 1.1e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CDOLBINB_01002 8.2e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDOLBINB_01003 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CDOLBINB_01004 6.1e-149 glcU U Glucose uptake
CDOLBINB_01005 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CDOLBINB_01006 9.3e-99 ycnI S protein conserved in bacteria
CDOLBINB_01007 3.6e-307 ycnJ P protein, homolog of Cu resistance protein CopC
CDOLBINB_01008 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
CDOLBINB_01009 2.6e-53
CDOLBINB_01010 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
CDOLBINB_01011 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
CDOLBINB_01012 4e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
CDOLBINB_01013 1.1e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
CDOLBINB_01014 2.1e-09 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CDOLBINB_01015 1.7e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CDOLBINB_01016 2.8e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
CDOLBINB_01017 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
CDOLBINB_01019 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
CDOLBINB_01020 8.8e-139 ycsF S Belongs to the UPF0271 (lamB) family
CDOLBINB_01021 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
CDOLBINB_01022 7.6e-146 ycsI S Belongs to the D-glutamate cyclase family
CDOLBINB_01023 1e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
CDOLBINB_01024 8.7e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
CDOLBINB_01025 2.7e-132 kipR K Transcriptional regulator
CDOLBINB_01026 6e-117 ycsK E anatomical structure formation involved in morphogenesis
CDOLBINB_01028 5.4e-49 yczJ S biosynthesis
CDOLBINB_01029 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
CDOLBINB_01030 2.9e-173 ydhF S Oxidoreductase
CDOLBINB_01031 0.0 mtlR K transcriptional regulator, MtlR
CDOLBINB_01032 6.7e-292 ydaB IQ acyl-CoA ligase
CDOLBINB_01033 2e-98 ydaC Q Methyltransferase domain
CDOLBINB_01034 3.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CDOLBINB_01035 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
CDOLBINB_01036 6.1e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CDOLBINB_01037 1.2e-76 ydaG 1.4.3.5 S general stress protein
CDOLBINB_01038 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
CDOLBINB_01039 2.5e-46 ydzA EGP Major facilitator Superfamily
CDOLBINB_01040 2.5e-74 lrpC K Transcriptional regulator
CDOLBINB_01041 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDOLBINB_01042 3.8e-204 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
CDOLBINB_01043 5.5e-150 ydaK T Diguanylate cyclase, GGDEF domain
CDOLBINB_01044 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
CDOLBINB_01045 1.3e-232 ydaM M Glycosyl transferase family group 2
CDOLBINB_01046 0.0 ydaN S Bacterial cellulose synthase subunit
CDOLBINB_01047 0.0 ydaO E amino acid
CDOLBINB_01048 1.6e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
CDOLBINB_01049 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
CDOLBINB_01051 1.8e-27
CDOLBINB_01052 6.5e-204 yraM S PrpF protein
CDOLBINB_01053 1.4e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
CDOLBINB_01054 4.2e-40 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CDOLBINB_01055 4.4e-149 S Alpha beta hydrolase
CDOLBINB_01056 1.7e-60 T sh3 domain protein
CDOLBINB_01057 2.4e-61 T sh3 domain protein
CDOLBINB_01058 1.3e-66 E Glyoxalase-like domain
CDOLBINB_01059 5.3e-37 yraG
CDOLBINB_01060 6.4e-63 yraF M Spore coat protein
CDOLBINB_01061 1.1e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CDOLBINB_01062 1.7e-25 yraE
CDOLBINB_01063 1.1e-49 yraD M Spore coat protein
CDOLBINB_01064 4.3e-47 yraB K helix_turn_helix, mercury resistance
CDOLBINB_01065 8.2e-25 yphJ 4.1.1.44 S peroxiredoxin activity
CDOLBINB_01066 3.3e-197 adhA 1.1.1.1 C alcohol dehydrogenase
CDOLBINB_01067 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
CDOLBINB_01068 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
CDOLBINB_01069 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
CDOLBINB_01070 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
CDOLBINB_01071 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
CDOLBINB_01072 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
CDOLBINB_01073 0.0 levR K PTS system fructose IIA component
CDOLBINB_01074 3.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
CDOLBINB_01075 3.6e-106 yrhP E LysE type translocator
CDOLBINB_01076 4.1e-150 yrhO K Archaeal transcriptional regulator TrmB
CDOLBINB_01077 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
CDOLBINB_01078 6.1e-149 rsiV S Protein of unknown function (DUF3298)
CDOLBINB_01079 0.0 yrhL I Acyltransferase family
CDOLBINB_01080 1.2e-43 yrhK S YrhK-like protein
CDOLBINB_01081 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
CDOLBINB_01082 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
CDOLBINB_01083 1.1e-92 yrhH Q methyltransferase
CDOLBINB_01086 1.8e-142 focA P Formate nitrite
CDOLBINB_01087 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
CDOLBINB_01088 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
CDOLBINB_01089 2.4e-78 yrhD S Protein of unknown function (DUF1641)
CDOLBINB_01090 4.6e-35 yrhC S YrhC-like protein
CDOLBINB_01091 6.3e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CDOLBINB_01092 6.8e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
CDOLBINB_01093 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDOLBINB_01094 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
CDOLBINB_01095 1e-25 yrzA S Protein of unknown function (DUF2536)
CDOLBINB_01096 1.2e-62 yrrS S Protein of unknown function (DUF1510)
CDOLBINB_01097 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
CDOLBINB_01098 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CDOLBINB_01099 8.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
CDOLBINB_01100 2.7e-246 yegQ O COG0826 Collagenase and related proteases
CDOLBINB_01101 1.1e-172 yegQ O Peptidase U32
CDOLBINB_01102 1.7e-119 yrrM 2.1.1.104 S O-methyltransferase
CDOLBINB_01103 3.7e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDOLBINB_01104 1.2e-45 yrzB S Belongs to the UPF0473 family
CDOLBINB_01105 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDOLBINB_01106 1.7e-41 yrzL S Belongs to the UPF0297 family
CDOLBINB_01107 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDOLBINB_01108 2.7e-170 yrrI S AI-2E family transporter
CDOLBINB_01109 1.9e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CDOLBINB_01110 4.8e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
CDOLBINB_01111 1.8e-108 gluC P ABC transporter
CDOLBINB_01112 7.6e-107 glnP P ABC transporter
CDOLBINB_01113 8e-08 S Protein of unknown function (DUF3918)
CDOLBINB_01114 9.8e-31 yrzR
CDOLBINB_01115 1.2e-82 yrrD S protein conserved in bacteria
CDOLBINB_01116 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CDOLBINB_01117 1.4e-15 S COG0457 FOG TPR repeat
CDOLBINB_01118 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CDOLBINB_01119 2.2e-210 iscS 2.8.1.7 E Cysteine desulfurase
CDOLBINB_01120 1.2e-70 cymR K Transcriptional regulator
CDOLBINB_01121 1.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
CDOLBINB_01122 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
CDOLBINB_01123 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDOLBINB_01124 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
CDOLBINB_01126 2.6e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
CDOLBINB_01127 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CDOLBINB_01128 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDOLBINB_01129 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDOLBINB_01130 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
CDOLBINB_01131 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
CDOLBINB_01132 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
CDOLBINB_01133 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDOLBINB_01134 1.6e-48 yrzD S Post-transcriptional regulator
CDOLBINB_01135 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CDOLBINB_01136 1.3e-111 yrbG S membrane
CDOLBINB_01137 2.2e-73 yrzE S Protein of unknown function (DUF3792)
CDOLBINB_01138 1.1e-38 yajC U Preprotein translocase subunit YajC
CDOLBINB_01139 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CDOLBINB_01140 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDOLBINB_01141 2.6e-18 yrzS S Protein of unknown function (DUF2905)
CDOLBINB_01142 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CDOLBINB_01143 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CDOLBINB_01144 4.8e-93 bofC S BofC C-terminal domain
CDOLBINB_01145 2.6e-252 csbX EGP Major facilitator Superfamily
CDOLBINB_01146 1.7e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
CDOLBINB_01147 7.2e-118 yrzF T serine threonine protein kinase
CDOLBINB_01149 8.7e-52 S Family of unknown function (DUF5412)
CDOLBINB_01150 5.3e-262 alsT E Sodium alanine symporter
CDOLBINB_01151 1.6e-126 yebC K transcriptional regulatory protein
CDOLBINB_01152 1.3e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CDOLBINB_01153 8.3e-157 safA M spore coat assembly protein SafA
CDOLBINB_01154 6.3e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDOLBINB_01155 8.1e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
CDOLBINB_01156 7e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
CDOLBINB_01157 4.8e-229 nifS 2.8.1.7 E Cysteine desulfurase
CDOLBINB_01158 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
CDOLBINB_01159 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
CDOLBINB_01160 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
CDOLBINB_01161 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDOLBINB_01162 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
CDOLBINB_01163 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CDOLBINB_01164 4.1e-56 ysxB J ribosomal protein
CDOLBINB_01165 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
CDOLBINB_01166 9.2e-161 spoIVFB S Stage IV sporulation protein
CDOLBINB_01167 2.5e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
CDOLBINB_01168 8e-143 minD D Belongs to the ParA family
CDOLBINB_01169 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CDOLBINB_01170 1.4e-84 mreD M shape-determining protein
CDOLBINB_01171 1.1e-156 mreC M Involved in formation and maintenance of cell shape
CDOLBINB_01172 1.8e-184 mreB D Rod shape-determining protein MreB
CDOLBINB_01173 6.5e-125 radC E Belongs to the UPF0758 family
CDOLBINB_01174 2.8e-102 maf D septum formation protein Maf
CDOLBINB_01175 1.9e-165 spoIIB S Sporulation related domain
CDOLBINB_01176 3.1e-125 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
CDOLBINB_01177 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CDOLBINB_01178 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CDOLBINB_01179 1.6e-25
CDOLBINB_01180 7.8e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDOLBINB_01181 4.4e-199 spoVID M stage VI sporulation protein D
CDOLBINB_01182 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
CDOLBINB_01183 8.1e-182 hemB 4.2.1.24 H Belongs to the ALAD family
CDOLBINB_01184 3.5e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
CDOLBINB_01185 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
CDOLBINB_01186 3.6e-146 hemX O cytochrome C
CDOLBINB_01187 7.2e-245 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CDOLBINB_01188 1.2e-88 ysxD
CDOLBINB_01189 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
CDOLBINB_01190 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDOLBINB_01191 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
CDOLBINB_01192 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDOLBINB_01193 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CDOLBINB_01194 1.9e-186 ysoA H Tetratricopeptide repeat
CDOLBINB_01195 1.2e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDOLBINB_01196 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDOLBINB_01197 1.3e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CDOLBINB_01198 2.1e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDOLBINB_01199 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDOLBINB_01200 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
CDOLBINB_01201 0.0 ilvB 2.2.1.6 E Acetolactate synthase
CDOLBINB_01203 9.6e-77 ysnE K acetyltransferase
CDOLBINB_01204 1.7e-110 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CDOLBINB_01205 9.4e-131 ysnF S protein conserved in bacteria
CDOLBINB_01206 4.3e-99 K Helix-turn-helix domain
CDOLBINB_01207 1.3e-15 K Transcriptional regulator
CDOLBINB_01208 1.3e-63
CDOLBINB_01209 6.1e-128 ftsK D FtsK/SpoIIIE family
CDOLBINB_01211 2.4e-20 S protein disulfide oxidoreductase activity
CDOLBINB_01212 1.2e-18 S YolD-like protein
CDOLBINB_01214 6.3e-33 S Bacteriophage A118-like holin, Hol118
CDOLBINB_01215 5.7e-148 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
CDOLBINB_01216 8.8e-30 S Haemolysin XhlA
CDOLBINB_01219 6.1e-45
CDOLBINB_01220 3.3e-74 lyc 3.2.1.17 M Glycosyl hydrolases family 25
CDOLBINB_01221 3e-68 S Phage tail protein
CDOLBINB_01222 2e-128 D Phage tail tape measure protein
CDOLBINB_01223 1.3e-30
CDOLBINB_01224 5.5e-72 N phage major tail protein, phi13 family
CDOLBINB_01225 2.2e-25
CDOLBINB_01227 7.6e-34 S Phage head-tail joining protein
CDOLBINB_01228 2e-25 S Phage gp6-like head-tail connector protein
CDOLBINB_01229 2.3e-28 N domain, Protein
CDOLBINB_01230 4.2e-161 S Phage capsid family
CDOLBINB_01231 2.7e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
CDOLBINB_01232 3.7e-222 S Phage portal protein
CDOLBINB_01233 0.0 S Terminase
CDOLBINB_01234 2.6e-44 L Phage terminase, small subunit
CDOLBINB_01235 4.6e-31 L HNH endonuclease
CDOLBINB_01237 2.9e-40
CDOLBINB_01241 2e-42 M Glycosyltransferase like family 2
CDOLBINB_01242 9.1e-28 K Cro/C1-type HTH DNA-binding domain
CDOLBINB_01243 1.3e-57 S Pfam:DUF867
CDOLBINB_01244 1.8e-107 3.2.1.15 M Right handed beta helix region
CDOLBINB_01248 5.3e-48
CDOLBINB_01249 4.6e-22
CDOLBINB_01251 5.8e-125 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
CDOLBINB_01253 2.1e-25 S Helix-turn-helix domain
CDOLBINB_01254 9.5e-12
CDOLBINB_01255 2.5e-35
CDOLBINB_01256 2.6e-43 K Sigma-70, region 4
CDOLBINB_01257 3.1e-07
CDOLBINB_01258 1.1e-130 S C-5 cytosine-specific DNA methylase
CDOLBINB_01259 4.5e-36 2.7.1.24 H dephospho-CoA kinase activity
CDOLBINB_01260 1.1e-39
CDOLBINB_01261 3.2e-14
CDOLBINB_01262 6.9e-35 S protein conserved in bacteria
CDOLBINB_01263 2.4e-26 thyX 2.1.1.148 H Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
CDOLBINB_01264 1.2e-57 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
CDOLBINB_01265 2.2e-89 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDOLBINB_01266 1.3e-53 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDOLBINB_01268 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDOLBINB_01269 1.9e-38 nrdI 1.17.4.1 F Belongs to the NrdI family
CDOLBINB_01272 2.9e-15 S Protein of unknown function (DUF1523)
CDOLBINB_01274 1.8e-32 ruvC 3.1.22.4 L Crossover junction endodeoxyribonuclease RuvC
CDOLBINB_01275 3e-103
CDOLBINB_01277 4.1e-194 L DNA polymerase A domain
CDOLBINB_01279 8.8e-38
CDOLBINB_01280 1.5e-47
CDOLBINB_01281 4.4e-45
CDOLBINB_01285 7e-09
CDOLBINB_01286 2.1e-57
CDOLBINB_01287 2.6e-08 S Cro/C1-type HTH DNA-binding domain
CDOLBINB_01288 5e-11 K Cro/C1-type HTH DNA-binding domain
CDOLBINB_01289 1.2e-138 dnaG L Toprim-like
CDOLBINB_01290 9.4e-208 3.6.4.12 L DnaB-like helicase C terminal domain
CDOLBINB_01292 1.3e-09 S YopX protein
CDOLBINB_01293 6.4e-13 yodN
CDOLBINB_01294 1.2e-114 L DNA-dependent DNA replication
CDOLBINB_01296 1.2e-40
CDOLBINB_01297 3.1e-22
CDOLBINB_01302 5.4e-09 S Helix-turn-helix domain
CDOLBINB_01304 6.7e-89 L Phage integrase family
CDOLBINB_01306 1.8e-92 ysnB S Phosphoesterase
CDOLBINB_01307 8.5e-102 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CDOLBINB_01308 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDOLBINB_01309 5e-196 gerM S COG5401 Spore germination protein
CDOLBINB_01310 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CDOLBINB_01311 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
CDOLBINB_01312 3.3e-30 gerE K Transcriptional regulator
CDOLBINB_01313 2.2e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
CDOLBINB_01314 1.7e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
CDOLBINB_01315 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
CDOLBINB_01316 2.4e-107 sdhC C succinate dehydrogenase
CDOLBINB_01317 1.2e-79 yslB S Protein of unknown function (DUF2507)
CDOLBINB_01318 1.8e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
CDOLBINB_01319 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CDOLBINB_01320 2e-52 trxA O Belongs to the thioredoxin family
CDOLBINB_01321 7.5e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
CDOLBINB_01323 2.1e-177 etfA C Electron transfer flavoprotein
CDOLBINB_01324 4.5e-135 etfB C Electron transfer flavoprotein
CDOLBINB_01325 1.2e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
CDOLBINB_01326 4e-99 fadR K Transcriptional regulator
CDOLBINB_01327 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CDOLBINB_01328 7.3e-68 yshE S membrane
CDOLBINB_01329 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CDOLBINB_01330 0.0 polX L COG1796 DNA polymerase IV (family X)
CDOLBINB_01331 1.3e-85 cvpA S membrane protein, required for colicin V production
CDOLBINB_01332 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CDOLBINB_01333 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDOLBINB_01334 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CDOLBINB_01335 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDOLBINB_01336 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDOLBINB_01337 2.6e-32 sspI S Belongs to the SspI family
CDOLBINB_01338 4.9e-207 ysfB KT regulator
CDOLBINB_01339 8.8e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
CDOLBINB_01340 6.2e-257 glcF C Glycolate oxidase
CDOLBINB_01341 4.5e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
CDOLBINB_01342 0.0 cstA T Carbon starvation protein
CDOLBINB_01343 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
CDOLBINB_01344 3.4e-144 araQ G transport system permease
CDOLBINB_01345 4.2e-167 araP G carbohydrate transport
CDOLBINB_01346 6.2e-254 araN G carbohydrate transport
CDOLBINB_01347 1.7e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
CDOLBINB_01348 8.6e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
CDOLBINB_01349 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
CDOLBINB_01350 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
CDOLBINB_01351 7.8e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
CDOLBINB_01352 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
CDOLBINB_01353 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
CDOLBINB_01354 3.5e-67 ysdB S Sigma-w pathway protein YsdB
CDOLBINB_01355 7.5e-45 ysdA S Membrane
CDOLBINB_01356 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDOLBINB_01357 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CDOLBINB_01358 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CDOLBINB_01360 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CDOLBINB_01361 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CDOLBINB_01362 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
CDOLBINB_01363 0.0 lytS 2.7.13.3 T Histidine kinase
CDOLBINB_01364 2.8e-148 ysaA S HAD-hyrolase-like
CDOLBINB_01365 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDOLBINB_01367 1.4e-158 ytxC S YtxC-like family
CDOLBINB_01368 1e-108 ytxB S SNARE associated Golgi protein
CDOLBINB_01369 2.5e-172 dnaI L Primosomal protein DnaI
CDOLBINB_01370 1.1e-264 dnaB L Membrane attachment protein
CDOLBINB_01371 3.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDOLBINB_01372 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CDOLBINB_01373 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CDOLBINB_01374 9.9e-67 ytcD K Transcriptional regulator
CDOLBINB_01375 2.5e-201 ytbD EGP Major facilitator Superfamily
CDOLBINB_01376 1.3e-159 ytbE S reductase
CDOLBINB_01377 2.2e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CDOLBINB_01378 1.1e-107 ytaF P Probably functions as a manganese efflux pump
CDOLBINB_01379 1.7e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CDOLBINB_01380 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDOLBINB_01381 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
CDOLBINB_01382 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CDOLBINB_01383 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
CDOLBINB_01384 4.1e-242 icd 1.1.1.42 C isocitrate
CDOLBINB_01385 1.1e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
CDOLBINB_01386 4.7e-71 yeaL S membrane
CDOLBINB_01387 4.4e-192 ytvI S sporulation integral membrane protein YtvI
CDOLBINB_01388 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
CDOLBINB_01389 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CDOLBINB_01390 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CDOLBINB_01391 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CDOLBINB_01392 7.1e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDOLBINB_01393 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
CDOLBINB_01394 0.0 dnaE 2.7.7.7 L DNA polymerase
CDOLBINB_01395 3.2e-56 ytrH S Sporulation protein YtrH
CDOLBINB_01396 8.2e-69 ytrI
CDOLBINB_01397 9.2e-29
CDOLBINB_01398 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
CDOLBINB_01399 2.4e-47 ytpI S YtpI-like protein
CDOLBINB_01400 8e-241 ytoI K transcriptional regulator containing CBS domains
CDOLBINB_01401 1.7e-130 ytkL S Belongs to the UPF0173 family
CDOLBINB_01402 1.4e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CDOLBINB_01404 9.9e-266 argH 4.3.2.1 E argininosuccinate lyase
CDOLBINB_01405 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CDOLBINB_01406 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
CDOLBINB_01407 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDOLBINB_01408 7e-165 ytxK 2.1.1.72 L DNA methylase
CDOLBINB_01409 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CDOLBINB_01410 8.7e-70 ytfJ S Sporulation protein YtfJ
CDOLBINB_01411 1.6e-110 ytfI S Protein of unknown function (DUF2953)
CDOLBINB_01412 2.5e-86 yteJ S RDD family
CDOLBINB_01413 3.9e-179 sppA OU signal peptide peptidase SppA
CDOLBINB_01414 8.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDOLBINB_01415 0.0 ytcJ S amidohydrolase
CDOLBINB_01416 5e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CDOLBINB_01417 2e-29 sspB S spore protein
CDOLBINB_01418 1.7e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDOLBINB_01419 5e-207 iscS2 2.8.1.7 E Cysteine desulfurase
CDOLBINB_01420 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
CDOLBINB_01421 4.6e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CDOLBINB_01422 1.7e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
CDOLBINB_01423 1e-108 yttP K Transcriptional regulator
CDOLBINB_01424 5.9e-88 ytsP 1.8.4.14 T GAF domain-containing protein
CDOLBINB_01425 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
CDOLBINB_01426 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDOLBINB_01428 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDOLBINB_01429 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CDOLBINB_01431 1.6e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
CDOLBINB_01432 5.1e-170 ybfA 3.4.15.5 K FR47-like protein
CDOLBINB_01433 9.4e-34 S Protein of unknown function (DUF2651)
CDOLBINB_01434 7.3e-258 glpT G -transporter
CDOLBINB_01435 1e-162 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CDOLBINB_01436 1.8e-290 ybeC E amino acid
CDOLBINB_01437 4.9e-41 ybyB
CDOLBINB_01438 7.8e-246 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
CDOLBINB_01439 5.2e-150 ybxI 3.5.2.6 V beta-lactamase
CDOLBINB_01440 4.9e-30 ybxH S Family of unknown function (DUF5370)
CDOLBINB_01441 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
CDOLBINB_01442 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
CDOLBINB_01443 8.6e-210 ybdO S Domain of unknown function (DUF4885)
CDOLBINB_01444 3.8e-151 ybdN
CDOLBINB_01445 3.9e-139 KLT Protein tyrosine kinase
CDOLBINB_01447 4.9e-57
CDOLBINB_01448 2.1e-200 ybcL EGP Major facilitator Superfamily
CDOLBINB_01449 5.1e-50 ybzH K Helix-turn-helix domain
CDOLBINB_01450 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
CDOLBINB_01451 3.3e-46
CDOLBINB_01453 3.2e-92 can 4.2.1.1 P carbonic anhydrase
CDOLBINB_01454 0.0 ybcC S Belongs to the UPF0753 family
CDOLBINB_01455 8.2e-274 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CDOLBINB_01456 0.0 wapA M COG3209 Rhs family protein
CDOLBINB_01457 2.1e-163 yxxF EG EamA-like transporter family
CDOLBINB_01458 1.1e-72 yxiE T Belongs to the universal stress protein A family
CDOLBINB_01459 4.6e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CDOLBINB_01460 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CDOLBINB_01461 5.5e-53
CDOLBINB_01462 1.7e-216 S nuclease activity
CDOLBINB_01463 1.4e-38 yxiC S Family of unknown function (DUF5344)
CDOLBINB_01464 2.3e-20 S Domain of unknown function (DUF5082)
CDOLBINB_01465 1.1e-280 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
CDOLBINB_01466 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
CDOLBINB_01467 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
CDOLBINB_01468 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CDOLBINB_01469 4.8e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
CDOLBINB_01470 4.4e-180 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
CDOLBINB_01471 6.8e-251 lysP E amino acid
CDOLBINB_01472 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
CDOLBINB_01473 1.7e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CDOLBINB_01474 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDOLBINB_01475 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CDOLBINB_01476 1.1e-150 yxxB S Domain of Unknown Function (DUF1206)
CDOLBINB_01477 3.4e-200 eutH E Ethanolamine utilisation protein, EutH
CDOLBINB_01478 8.9e-248 yxeQ S MmgE/PrpD family
CDOLBINB_01479 6.1e-213 yxeP 3.5.1.47 E hydrolase activity
CDOLBINB_01480 2.7e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
CDOLBINB_01481 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
CDOLBINB_01482 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
CDOLBINB_01483 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CDOLBINB_01484 1.4e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDOLBINB_01485 2e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
CDOLBINB_01486 1.8e-150 yidA S hydrolases of the HAD superfamily
CDOLBINB_01489 1.3e-20 yxeE
CDOLBINB_01490 5.6e-16 yxeD
CDOLBINB_01491 1.4e-68
CDOLBINB_01492 1.1e-175 fhuD P ABC transporter
CDOLBINB_01493 5.9e-58 yxeA S Protein of unknown function (DUF1093)
CDOLBINB_01494 0.0 yxdM V ABC transporter (permease)
CDOLBINB_01495 2.6e-138 yxdL V ABC transporter, ATP-binding protein
CDOLBINB_01496 3.4e-180 T PhoQ Sensor
CDOLBINB_01497 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CDOLBINB_01498 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
CDOLBINB_01499 5.6e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
CDOLBINB_01500 8.6e-167 iolH G Xylose isomerase-like TIM barrel
CDOLBINB_01501 8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
CDOLBINB_01502 8.6e-235 iolF EGP Major facilitator Superfamily
CDOLBINB_01503 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
CDOLBINB_01504 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
CDOLBINB_01505 3.2e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
CDOLBINB_01506 6.6e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
CDOLBINB_01507 1.1e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CDOLBINB_01508 4.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
CDOLBINB_01509 8.3e-176 iolS C Aldo keto reductase
CDOLBINB_01511 1.4e-47 yxcD S Protein of unknown function (DUF2653)
CDOLBINB_01512 1e-91 S CGNR zinc finger
CDOLBINB_01513 8.9e-79 T HPP family
CDOLBINB_01514 3.1e-243 csbC EGP Major facilitator Superfamily
CDOLBINB_01515 0.0 htpG O Molecular chaperone. Has ATPase activity
CDOLBINB_01517 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
CDOLBINB_01518 9.1e-209 yxbF K Bacterial regulatory proteins, tetR family
CDOLBINB_01519 1.7e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
CDOLBINB_01520 6.7e-33 yxaI S membrane protein domain
CDOLBINB_01521 1.3e-91 S PQQ-like domain
CDOLBINB_01522 4.1e-61 S Family of unknown function (DUF5391)
CDOLBINB_01523 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CDOLBINB_01524 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CDOLBINB_01525 1.6e-185 pspF K Transcriptional regulator
CDOLBINB_01526 4.2e-110 hlyIII S protein, Hemolysin III
CDOLBINB_01527 5.8e-109 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CDOLBINB_01528 4.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CDOLBINB_01529 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
CDOLBINB_01530 2.3e-113 ypjP S YpjP-like protein
CDOLBINB_01531 9.1e-144 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
CDOLBINB_01532 1.7e-75 yphP S Belongs to the UPF0403 family
CDOLBINB_01533 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CDOLBINB_01534 1.7e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
CDOLBINB_01535 9.9e-109 ypgQ S phosphohydrolase
CDOLBINB_01536 2.6e-88 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
CDOLBINB_01537 1.4e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDOLBINB_01538 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
CDOLBINB_01539 1e-30 cspD K Cold-shock protein
CDOLBINB_01540 3.8e-16 degR
CDOLBINB_01541 8.1e-31 S Protein of unknown function (DUF2564)
CDOLBINB_01542 3e-29 ypeQ S Zinc-finger
CDOLBINB_01543 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
CDOLBINB_01544 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CDOLBINB_01545 2.7e-67 rnhA 3.1.26.4 L Ribonuclease
CDOLBINB_01547 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
CDOLBINB_01548 2e-07
CDOLBINB_01549 8.5e-38 ypbS S Protein of unknown function (DUF2533)
CDOLBINB_01550 0.0 ypbR S Dynamin family
CDOLBINB_01551 5.1e-87 ypbQ S protein conserved in bacteria
CDOLBINB_01552 2.8e-207 bcsA Q Naringenin-chalcone synthase
CDOLBINB_01553 3.8e-227 pbuX F xanthine
CDOLBINB_01554 1.3e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CDOLBINB_01555 3.3e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CDOLBINB_01556 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
CDOLBINB_01557 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
CDOLBINB_01558 4.2e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
CDOLBINB_01559 1.5e-186 ptxS K transcriptional
CDOLBINB_01560 1.4e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CDOLBINB_01561 1.9e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CDOLBINB_01562 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
CDOLBINB_01564 1.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CDOLBINB_01565 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CDOLBINB_01566 8.2e-91 ypsA S Belongs to the UPF0398 family
CDOLBINB_01567 6.2e-235 yprB L RNase_H superfamily
CDOLBINB_01568 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
CDOLBINB_01569 1.9e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
CDOLBINB_01570 1.6e-70 hspX O Belongs to the small heat shock protein (HSP20) family
CDOLBINB_01571 1.2e-48 yppG S YppG-like protein
CDOLBINB_01573 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
CDOLBINB_01576 2.9e-184 yppC S Protein of unknown function (DUF2515)
CDOLBINB_01577 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CDOLBINB_01578 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
CDOLBINB_01579 3e-92 ypoC
CDOLBINB_01580 8.3e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDOLBINB_01581 4.8e-128 dnaD L DNA replication protein DnaD
CDOLBINB_01582 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
CDOLBINB_01583 4.8e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CDOLBINB_01584 2.2e-79 ypmB S protein conserved in bacteria
CDOLBINB_01585 6.7e-23 ypmA S Protein of unknown function (DUF4264)
CDOLBINB_01586 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CDOLBINB_01587 4.6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CDOLBINB_01588 1.2e-155 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDOLBINB_01589 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
CDOLBINB_01590 2.5e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CDOLBINB_01591 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CDOLBINB_01592 5.3e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
CDOLBINB_01593 4.5e-129 bshB1 S proteins, LmbE homologs
CDOLBINB_01594 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
CDOLBINB_01595 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CDOLBINB_01596 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
CDOLBINB_01597 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
CDOLBINB_01598 6.1e-143 ypjB S sporulation protein
CDOLBINB_01599 4.4e-98 ypjA S membrane
CDOLBINB_01600 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
CDOLBINB_01601 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
CDOLBINB_01602 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
CDOLBINB_01603 4.2e-77 ypiF S Protein of unknown function (DUF2487)
CDOLBINB_01604 2.8e-99 ypiB S Belongs to the UPF0302 family
CDOLBINB_01605 2.7e-233 S COG0457 FOG TPR repeat
CDOLBINB_01606 1.7e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CDOLBINB_01607 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
CDOLBINB_01608 2.2e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDOLBINB_01609 1.5e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CDOLBINB_01610 6.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CDOLBINB_01611 1.8e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
CDOLBINB_01612 3.1e-112 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
CDOLBINB_01613 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDOLBINB_01614 5.6e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDOLBINB_01615 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
CDOLBINB_01616 2e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDOLBINB_01617 6.1e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDOLBINB_01618 2.1e-140 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
CDOLBINB_01619 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CDOLBINB_01620 1.7e-193 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CDOLBINB_01621 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CDOLBINB_01622 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
CDOLBINB_01623 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
CDOLBINB_01624 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
CDOLBINB_01625 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CDOLBINB_01626 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CDOLBINB_01627 1.3e-136 yphF
CDOLBINB_01628 1.6e-18 yphE S Protein of unknown function (DUF2768)
CDOLBINB_01629 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CDOLBINB_01630 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CDOLBINB_01631 5.1e-27 ypzH
CDOLBINB_01632 2.5e-161 seaA S YIEGIA protein
CDOLBINB_01633 1.1e-101 yphA
CDOLBINB_01634 1e-07 S YpzI-like protein
CDOLBINB_01635 3.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CDOLBINB_01636 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
CDOLBINB_01637 6.8e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CDOLBINB_01638 5e-21 S Family of unknown function (DUF5359)
CDOLBINB_01639 2.7e-112 ypfA M Flagellar protein YcgR
CDOLBINB_01640 5.5e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
CDOLBINB_01641 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
CDOLBINB_01642 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
CDOLBINB_01643 8.7e-176 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
CDOLBINB_01644 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
CDOLBINB_01645 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CDOLBINB_01646 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
CDOLBINB_01647 2.8e-81 ypbF S Protein of unknown function (DUF2663)
CDOLBINB_01648 2.2e-78 ypbE M Lysin motif
CDOLBINB_01649 1.7e-97 ypbD S metal-dependent membrane protease
CDOLBINB_01650 2.5e-283 recQ 3.6.4.12 L DNA helicase
CDOLBINB_01651 1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
CDOLBINB_01652 4.7e-41 fer C Ferredoxin
CDOLBINB_01653 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CDOLBINB_01654 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDOLBINB_01655 6.1e-132 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CDOLBINB_01656 1.5e-184 rsiX
CDOLBINB_01657 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
CDOLBINB_01658 0.0 resE 2.7.13.3 T Histidine kinase
CDOLBINB_01659 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CDOLBINB_01660 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
CDOLBINB_01661 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
CDOLBINB_01662 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
CDOLBINB_01663 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CDOLBINB_01664 1.9e-87 spmB S Spore maturation protein
CDOLBINB_01665 3.5e-103 spmA S Spore maturation protein
CDOLBINB_01666 4e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
CDOLBINB_01667 1.7e-96 ypuI S Protein of unknown function (DUF3907)
CDOLBINB_01668 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDOLBINB_01669 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDOLBINB_01670 9.4e-92 ypuF S Domain of unknown function (DUF309)
CDOLBINB_01671 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CDOLBINB_01672 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CDOLBINB_01673 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDOLBINB_01674 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
CDOLBINB_01675 6.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDOLBINB_01676 7.8e-55 ypuD
CDOLBINB_01677 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CDOLBINB_01678 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
CDOLBINB_01680 0.0 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDOLBINB_01682 2.5e-77 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDOLBINB_01685 5e-93 ntd 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
CDOLBINB_01689 4.1e-09 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
CDOLBINB_01690 3e-77 DR0488 T 3D domain protein
CDOLBINB_01693 2.1e-89 2.7.1.24 H dephospho-CoA kinase activity
CDOLBINB_01694 1.2e-57 K Cro/C1-type HTH DNA-binding domain
CDOLBINB_01696 8.6e-09
CDOLBINB_01699 4.5e-43 ligA 6.5.1.2 L NAD-dependent DNA ligase adenylation domain
CDOLBINB_01700 1.6e-35
CDOLBINB_01702 0.0 L 3'-5' exonuclease
CDOLBINB_01704 8.5e-21 S PQ loop repeat
CDOLBINB_01705 9.2e-113 dak 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
CDOLBINB_01707 1.1e-90 tdk 2.7.1.21 F thymidine kinase
CDOLBINB_01708 6.9e-151 L RNA ligase
CDOLBINB_01710 2e-83 ruvC 3.1.22.4 L Crossover junction endodeoxyribonuclease RuvC
CDOLBINB_01711 1.7e-170
CDOLBINB_01715 3.6e-123
CDOLBINB_01719 3.7e-179 L Toprim-like
CDOLBINB_01721 3.3e-244 3.6.4.12 L AAA domain
CDOLBINB_01722 2.5e-141 dnaI L DNA-dependent DNA replication
CDOLBINB_01723 2.5e-136 K Helix-turn-helix domain
CDOLBINB_01724 3.9e-126 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CDOLBINB_01725 6.6e-67 S phage lysis holin
CDOLBINB_01727 0.0 3.2.1.4, 3.2.1.78 GH26,GH5,GH9 L Phage minor structural protein
CDOLBINB_01728 7.4e-300 S Phage tail protein
CDOLBINB_01729 7.5e-196 D minor tail protein
CDOLBINB_01731 9.2e-44
CDOLBINB_01732 7.4e-69 lmaA S Phage tail tube protein
CDOLBINB_01734 3.6e-57
CDOLBINB_01735 7.3e-50
CDOLBINB_01736 4.4e-74
CDOLBINB_01738 9.5e-150
CDOLBINB_01739 9.9e-07
CDOLBINB_01741 1.3e-152 S Phage minor capsid protein 2
CDOLBINB_01742 5.4e-273 S Phage portal protein, SPP1 Gp6-like
CDOLBINB_01743 0.0 S TIGRFAM Phage
CDOLBINB_01744 7.9e-124 L resolvase
CDOLBINB_01745 5.6e-128
CDOLBINB_01746 1.2e-62
CDOLBINB_01749 4.2e-56 yozO S Bacterial PH domain
CDOLBINB_01750 1.9e-36 yocN
CDOLBINB_01751 1.1e-40 yozN
CDOLBINB_01752 6.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
CDOLBINB_01753 2e-30
CDOLBINB_01754 1.6e-52 yocL
CDOLBINB_01755 5.7e-83 dksA T general stress protein
CDOLBINB_01756 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDOLBINB_01757 0.0 recQ 3.6.4.12 L DNA helicase
CDOLBINB_01758 1.7e-111 yocH CBM50 M COG1388 FOG LysM repeat
CDOLBINB_01759 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CDOLBINB_01760 4.6e-197 desK 2.7.13.3 T Histidine kinase
CDOLBINB_01761 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
CDOLBINB_01762 3.8e-187 yocD 3.4.17.13 V peptidase S66
CDOLBINB_01763 1.6e-93 yocC
CDOLBINB_01764 6.4e-145
CDOLBINB_01765 1.5e-92 yozB S membrane
CDOLBINB_01766 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CDOLBINB_01767 8.4e-51 czrA K transcriptional
CDOLBINB_01768 6.3e-91 yobW
CDOLBINB_01769 1.3e-171 yobV K WYL domain
CDOLBINB_01770 1.9e-86 yobU K Bacterial transcription activator, effector binding domain
CDOLBINB_01771 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
CDOLBINB_01772 3.3e-98 yobS K Transcriptional regulator
CDOLBINB_01773 4.6e-137 yobR 2.3.1.1 J FR47-like protein
CDOLBINB_01774 2.3e-133 yobQ K helix_turn_helix, arabinose operon control protein
CDOLBINB_01775 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
CDOLBINB_01776 2.2e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
CDOLBINB_01777 1.7e-102 yokH G SMI1 / KNR4 family
CDOLBINB_01778 4.2e-309 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CDOLBINB_01779 3.3e-85 S SMI1-KNR4 cell-wall
CDOLBINB_01780 3.7e-47
CDOLBINB_01782 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
CDOLBINB_01783 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
CDOLBINB_01786 2.4e-167 bla 3.5.2.6 V beta-lactamase
CDOLBINB_01787 7.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
CDOLBINB_01788 2.7e-76 yoaW
CDOLBINB_01789 3.9e-159 yijE EG EamA-like transporter family
CDOLBINB_01790 3.3e-158 yoaU K LysR substrate binding domain
CDOLBINB_01791 3.3e-149 yoaT S Protein of unknown function (DUF817)
CDOLBINB_01792 3.9e-29 yozG K Transcriptional regulator
CDOLBINB_01793 7.3e-75 yoaS S Protein of unknown function (DUF2975)
CDOLBINB_01794 7.1e-172 yoaR V vancomycin resistance protein
CDOLBINB_01795 1.1e-84
CDOLBINB_01798 8.7e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
CDOLBINB_01801 4.6e-131 yoqW S Belongs to the SOS response-associated peptidase family
CDOLBINB_01802 1.4e-195 pelB 4.2.2.10, 4.2.2.2 G Amb_all
CDOLBINB_01803 2e-110 yoaK S Membrane
CDOLBINB_01804 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
CDOLBINB_01805 2.1e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
CDOLBINB_01806 1.5e-178 mcpU NT methyl-accepting chemotaxis protein
CDOLBINB_01807 7.7e-35 S Protein of unknown function (DUF4025)
CDOLBINB_01808 2.6e-13
CDOLBINB_01809 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
CDOLBINB_01810 1.1e-33 yoaF
CDOLBINB_01811 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CDOLBINB_01812 2.6e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDOLBINB_01813 8.5e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
CDOLBINB_01814 9.9e-233 yoaB EGP Major facilitator Superfamily
CDOLBINB_01815 6.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
CDOLBINB_01816 2.8e-139 V AAA domain, putative AbiEii toxin, Type IV TA system
CDOLBINB_01817 6.4e-94 V ABC-2 family transporter protein
CDOLBINB_01818 1.1e-125 V ABC-2 family transporter protein
CDOLBINB_01819 5.6e-92 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CDOLBINB_01820 1.3e-134 yoxB
CDOLBINB_01821 3.5e-38 yoxC S Bacterial protein of unknown function (DUF948)
CDOLBINB_01822 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CDOLBINB_01823 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
CDOLBINB_01824 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDOLBINB_01825 1.1e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDOLBINB_01826 7.8e-155 gltC K Transcriptional regulator
CDOLBINB_01827 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
CDOLBINB_01828 1.7e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
CDOLBINB_01829 3.3e-183 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CDOLBINB_01830 3e-156 gltR1 K Transcriptional regulator
CDOLBINB_01831 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
CDOLBINB_01832 8.7e-34 yoeD G Helix-turn-helix domain
CDOLBINB_01833 2.2e-96 L Integrase
CDOLBINB_01835 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
CDOLBINB_01836 6.2e-35 yesY E GDSL-like Lipase/Acylhydrolase
CDOLBINB_01837 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
CDOLBINB_01838 0.0 yetA
CDOLBINB_01839 5.8e-288 lplA G Bacterial extracellular solute-binding protein
CDOLBINB_01840 3.2e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
CDOLBINB_01841 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
CDOLBINB_01842 2.4e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
CDOLBINB_01843 2.6e-121 yetF S membrane
CDOLBINB_01844 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
CDOLBINB_01845 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CDOLBINB_01846 2.4e-34
CDOLBINB_01847 1.9e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CDOLBINB_01848 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
CDOLBINB_01849 5.3e-105 yetJ S Belongs to the BI1 family
CDOLBINB_01850 4.4e-153 yetK EG EamA-like transporter family
CDOLBINB_01851 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
CDOLBINB_01852 4.9e-207 yetM CH FAD binding domain
CDOLBINB_01853 3.4e-39 S COG NOG14552 non supervised orthologous group
CDOLBINB_01854 1e-257 iolT EGP Major facilitator Superfamily
CDOLBINB_01855 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
CDOLBINB_01856 4.5e-64 ydjM M Lytic transglycolase
CDOLBINB_01857 2.7e-151 ydjN U Involved in the tonB-independent uptake of proteins
CDOLBINB_01859 1.4e-34 ydjO S Cold-inducible protein YdjO
CDOLBINB_01860 5.8e-157 ydjP I Alpha/beta hydrolase family
CDOLBINB_01861 2e-175 yeaA S Protein of unknown function (DUF4003)
CDOLBINB_01862 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
CDOLBINB_01863 4.4e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
CDOLBINB_01864 4.9e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDOLBINB_01865 3.9e-176 yeaC S COG0714 MoxR-like ATPases
CDOLBINB_01866 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
CDOLBINB_01867 0.0 yebA E COG1305 Transglutaminase-like enzymes
CDOLBINB_01868 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CDOLBINB_01869 1.2e-83 K Belongs to the sigma-70 factor family. ECF subfamily
CDOLBINB_01870 4.8e-255 S Domain of unknown function (DUF4179)
CDOLBINB_01871 2.3e-211 pbuG S permease
CDOLBINB_01872 4.4e-117 yebC M Membrane
CDOLBINB_01874 8.9e-93 yebE S UPF0316 protein
CDOLBINB_01875 8e-28 yebG S NETI protein
CDOLBINB_01876 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CDOLBINB_01877 6.6e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDOLBINB_01878 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDOLBINB_01879 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CDOLBINB_01880 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDOLBINB_01881 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDOLBINB_01882 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDOLBINB_01883 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CDOLBINB_01884 7.1e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CDOLBINB_01885 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDOLBINB_01886 1.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CDOLBINB_01887 1.3e-232 purD 6.3.4.13 F Belongs to the GARS family
CDOLBINB_01888 1e-72 K helix_turn_helix ASNC type
CDOLBINB_01889 1.7e-227 yjeH E Amino acid permease
CDOLBINB_01890 2.7e-27 S Protein of unknown function (DUF2892)
CDOLBINB_01891 0.0 yerA 3.5.4.2 F adenine deaminase
CDOLBINB_01892 6.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
CDOLBINB_01893 4.8e-51 yerC S protein conserved in bacteria
CDOLBINB_01894 1.4e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
CDOLBINB_01896 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CDOLBINB_01897 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CDOLBINB_01898 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDOLBINB_01899 2.7e-219 camS S COG4851 Protein involved in sex pheromone biosynthesis
CDOLBINB_01900 6e-196 yerI S homoserine kinase type II (protein kinase fold)
CDOLBINB_01901 1.6e-123 sapB S MgtC SapB transporter
CDOLBINB_01902 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDOLBINB_01903 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDOLBINB_01904 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CDOLBINB_01905 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDOLBINB_01906 1e-143 yerO K Transcriptional regulator
CDOLBINB_01907 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDOLBINB_01908 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CDOLBINB_01909 1.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDOLBINB_01910 3.3e-60 yvbF K Belongs to the GbsR family
CDOLBINB_01911 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
CDOLBINB_01912 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CDOLBINB_01913 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
CDOLBINB_01914 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CDOLBINB_01915 3.5e-97 yvbF K Belongs to the GbsR family
CDOLBINB_01916 1.4e-102 yvbG U UPF0056 membrane protein
CDOLBINB_01917 1.9e-112 yvbH S YvbH-like oligomerisation region
CDOLBINB_01918 8.8e-122 exoY M Membrane
CDOLBINB_01919 0.0 tcaA S response to antibiotic
CDOLBINB_01920 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
CDOLBINB_01921 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CDOLBINB_01922 3.7e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
CDOLBINB_01923 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CDOLBINB_01924 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CDOLBINB_01925 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CDOLBINB_01926 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CDOLBINB_01927 1.1e-251 araE EGP Major facilitator Superfamily
CDOLBINB_01928 4.6e-202 araR K transcriptional
CDOLBINB_01929 4.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDOLBINB_01930 1.5e-158 yvbU K Transcriptional regulator
CDOLBINB_01931 4.7e-155 yvbV EG EamA-like transporter family
CDOLBINB_01932 1.1e-240 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
CDOLBINB_01933 4.1e-184 yvbX S Glycosyl hydrolase
CDOLBINB_01934 3.3e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CDOLBINB_01935 4.6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
CDOLBINB_01936 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CDOLBINB_01937 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CDOLBINB_01938 6.9e-193 desK 2.7.13.3 T Histidine kinase
CDOLBINB_01939 2e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
CDOLBINB_01940 1.5e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
CDOLBINB_01941 7.5e-157 rsbQ S Alpha/beta hydrolase family
CDOLBINB_01942 1.3e-197 rsbU 3.1.3.3 T response regulator
CDOLBINB_01943 2.9e-251 galA 3.2.1.89 G arabinogalactan
CDOLBINB_01944 0.0 lacA 3.2.1.23 G beta-galactosidase
CDOLBINB_01945 7.2e-150 ganQ P transport
CDOLBINB_01946 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
CDOLBINB_01947 2.3e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
CDOLBINB_01948 4e-184 lacR K Transcriptional regulator
CDOLBINB_01949 2.3e-112 yvfI K COG2186 Transcriptional regulators
CDOLBINB_01950 6.3e-307 yvfH C L-lactate permease
CDOLBINB_01951 2e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
CDOLBINB_01952 1e-31 yvfG S YvfG protein
CDOLBINB_01953 1.3e-184 yvfF GM Exopolysaccharide biosynthesis protein
CDOLBINB_01954 2.9e-218 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
CDOLBINB_01955 1e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
CDOLBINB_01956 1.2e-106 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CDOLBINB_01957 1.2e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CDOLBINB_01958 3.1e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
CDOLBINB_01959 3.2e-203 epsI GM pyruvyl transferase
CDOLBINB_01960 3.4e-194 epsH GT2 S Glycosyltransferase like family 2
CDOLBINB_01961 2.4e-206 epsG S EpsG family
CDOLBINB_01962 4.9e-218 epsF GT4 M Glycosyl transferases group 1
CDOLBINB_01963 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CDOLBINB_01964 6.8e-220 epsD GT4 M Glycosyl transferase 4-like
CDOLBINB_01965 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
CDOLBINB_01966 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
CDOLBINB_01967 8.9e-122 ywqC M biosynthesis protein
CDOLBINB_01968 2.8e-76 slr K transcriptional
CDOLBINB_01969 2e-285 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
CDOLBINB_01971 4.6e-93 padC Q Phenolic acid decarboxylase
CDOLBINB_01972 1.1e-72 MA20_18690 S Protein of unknown function (DUF3237)
CDOLBINB_01973 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
CDOLBINB_01974 1.1e-258 pbpE V Beta-lactamase
CDOLBINB_01975 9.3e-66
CDOLBINB_01976 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
CDOLBINB_01977 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
CDOLBINB_01978 1.8e-295 yveA E amino acid
CDOLBINB_01979 2.6e-106 yvdT K Transcriptional regulator
CDOLBINB_01980 6.7e-51 ykkC P Small Multidrug Resistance protein
CDOLBINB_01981 4.1e-50 sugE P Small Multidrug Resistance protein
CDOLBINB_01982 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
CDOLBINB_01984 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CDOLBINB_01985 3.1e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
CDOLBINB_01986 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
CDOLBINB_01987 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
CDOLBINB_01988 3.7e-157 malA S Protein of unknown function (DUF1189)
CDOLBINB_01989 6.6e-148 malD P transport
CDOLBINB_01990 1.4e-242 malC P COG1175 ABC-type sugar transport systems, permease components
CDOLBINB_01991 1.6e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
CDOLBINB_01992 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
CDOLBINB_01993 1.1e-172 yvdE K Transcriptional regulator
CDOLBINB_01994 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
CDOLBINB_01995 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
CDOLBINB_01996 2.3e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
CDOLBINB_01997 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
CDOLBINB_01998 4.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDOLBINB_01999 0.0 yxdM V ABC transporter (permease)
CDOLBINB_02000 5.6e-141 yvcR V ABC transporter, ATP-binding protein
CDOLBINB_02001 1.7e-196 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
CDOLBINB_02002 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CDOLBINB_02003 2.8e-31
CDOLBINB_02004 4.6e-140 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
CDOLBINB_02005 1.6e-36 crh G Phosphocarrier protein Chr
CDOLBINB_02006 1.4e-170 whiA K May be required for sporulation
CDOLBINB_02007 2.8e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CDOLBINB_02008 1.7e-165 rapZ S Displays ATPase and GTPase activities
CDOLBINB_02009 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CDOLBINB_02010 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CDOLBINB_02011 2.8e-98 usp CBM50 M protein conserved in bacteria
CDOLBINB_02012 1.1e-275 S COG0457 FOG TPR repeat
CDOLBINB_02013 0.0 msbA2 3.6.3.44 V ABC transporter
CDOLBINB_02015 0.0
CDOLBINB_02016 2e-68
CDOLBINB_02017 2.2e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
CDOLBINB_02018 8.9e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CDOLBINB_02019 3.2e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDOLBINB_02020 2.8e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDOLBINB_02021 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
CDOLBINB_02022 1.7e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDOLBINB_02023 9.6e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CDOLBINB_02024 2e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CDOLBINB_02025 1e-139 yvpB NU protein conserved in bacteria
CDOLBINB_02026 1.3e-117 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
CDOLBINB_02027 9.6e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
CDOLBINB_02028 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
CDOLBINB_02029 3.4e-161 yvoD P COG0370 Fe2 transport system protein B
CDOLBINB_02030 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDOLBINB_02031 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CDOLBINB_02032 4.6e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDOLBINB_02033 1.6e-129 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CDOLBINB_02034 1.8e-133 yvoA K transcriptional
CDOLBINB_02035 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
CDOLBINB_02036 3.6e-71 adcR K helix_turn_helix multiple antibiotic resistance protein
CDOLBINB_02037 1.2e-97 cypX 1.14.15.13 C Cytochrome P450
CDOLBINB_02038 1.5e-104 cypX 1.14.15.13 C Cytochrome P450
CDOLBINB_02039 3e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
CDOLBINB_02040 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
CDOLBINB_02041 2.7e-203 yvmA EGP Major facilitator Superfamily
CDOLBINB_02042 1.2e-50 yvlD S Membrane
CDOLBINB_02043 2.6e-26 pspB KT PspC domain
CDOLBINB_02044 2.4e-166 yvlB S Putative adhesin
CDOLBINB_02045 1.8e-48 yvlA
CDOLBINB_02046 5.7e-33 yvkN
CDOLBINB_02047 9.2e-78 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDOLBINB_02048 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CDOLBINB_02049 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CDOLBINB_02050 1.2e-30 csbA S protein conserved in bacteria
CDOLBINB_02051 0.0 yvkC 2.7.9.2 GT Phosphotransferase
CDOLBINB_02052 7e-101 yvkB K Transcriptional regulator
CDOLBINB_02053 2.8e-225 yvkA EGP Major facilitator Superfamily
CDOLBINB_02054 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDOLBINB_02055 5.3e-56 swrA S Swarming motility protein
CDOLBINB_02056 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
CDOLBINB_02057 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CDOLBINB_02058 1.6e-123 ftsE D cell division ATP-binding protein FtsE
CDOLBINB_02059 1e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
CDOLBINB_02060 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
CDOLBINB_02061 1e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CDOLBINB_02062 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CDOLBINB_02063 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CDOLBINB_02064 1.8e-65
CDOLBINB_02065 1.9e-08 fliT S bacterial-type flagellum organization
CDOLBINB_02066 2.9e-69 fliS N flagellar protein FliS
CDOLBINB_02067 3.7e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CDOLBINB_02068 6.1e-57 flaG N flagellar protein FlaG
CDOLBINB_02069 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDOLBINB_02070 9.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CDOLBINB_02071 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CDOLBINB_02072 2.2e-49 yviE
CDOLBINB_02073 7.8e-155 flgL N Belongs to the bacterial flagellin family
CDOLBINB_02074 3e-263 flgK N flagellar hook-associated protein
CDOLBINB_02075 4.6e-77 flgN NOU FlgN protein
CDOLBINB_02076 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
CDOLBINB_02077 7e-74 yvyF S flagellar protein
CDOLBINB_02078 2.3e-125 comFC S Phosphoribosyl transferase domain
CDOLBINB_02079 1.1e-44 comFB S Late competence development protein ComFB
CDOLBINB_02080 6.4e-265 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CDOLBINB_02081 7.3e-155 degV S protein conserved in bacteria
CDOLBINB_02082 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CDOLBINB_02083 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
CDOLBINB_02084 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
CDOLBINB_02085 5.6e-163 yvhJ K Transcriptional regulator
CDOLBINB_02086 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
CDOLBINB_02087 7.3e-233 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
CDOLBINB_02088 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
CDOLBINB_02089 5.1e-114 tuaF M protein involved in exopolysaccharide biosynthesis
CDOLBINB_02090 1.1e-262 tuaE M Teichuronic acid biosynthesis protein
CDOLBINB_02091 3.1e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDOLBINB_02092 6.9e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
CDOLBINB_02093 1.7e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CDOLBINB_02094 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CDOLBINB_02095 1.9e-94 M Glycosyltransferase like family 2
CDOLBINB_02096 2.5e-206 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CDOLBINB_02097 0.0 lytB 3.5.1.28 D Stage II sporulation protein
CDOLBINB_02098 3.8e-11
CDOLBINB_02099 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
CDOLBINB_02100 1.5e-214 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CDOLBINB_02101 2.1e-88 M Glycosyltransferase like family 2
CDOLBINB_02102 4.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
CDOLBINB_02103 2.8e-23 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
CDOLBINB_02104 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CDOLBINB_02105 1.9e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CDOLBINB_02106 1e-132 tagG GM Transport permease protein
CDOLBINB_02107 2.4e-10 xkdO L Transglycosylase SLT domain
CDOLBINB_02108 2.3e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
CDOLBINB_02109 6.1e-76 xkdM S Phage tail tube protein
CDOLBINB_02110 1.2e-255 xkdK S Phage tail sheath C-terminal domain
CDOLBINB_02111 1.9e-77 xkdJ
CDOLBINB_02112 9.9e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
CDOLBINB_02113 3.3e-64 yqbH S Domain of unknown function (DUF3599)
CDOLBINB_02114 5.1e-63 yqbG S Protein of unknown function (DUF3199)
CDOLBINB_02115 5.8e-169 xkdG S Phage capsid family
CDOLBINB_02116 1e-132 yqbD 2.1.1.72 L Putative phage serine protease XkdF
CDOLBINB_02117 1.6e-285 yqbA S portal protein
CDOLBINB_02118 1.2e-252 xtmB S phage terminase, large subunit
CDOLBINB_02119 5.3e-139 xtmA L phage terminase small subunit
CDOLBINB_02120 2.4e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
CDOLBINB_02121 1.8e-09 yqaO S Phage-like element PBSX protein XtrA
CDOLBINB_02125 6.4e-119 xkdC L Bacterial dnaA protein
CDOLBINB_02126 2.9e-156 xkdB K sequence-specific DNA binding
CDOLBINB_02128 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
CDOLBINB_02129 1e-110 xkdA E IrrE N-terminal-like domain
CDOLBINB_02130 4.4e-160 ydbD P Catalase
CDOLBINB_02131 3.3e-109 yjqB S Pfam:DUF867
CDOLBINB_02132 5.2e-60 yjqA S Bacterial PH domain
CDOLBINB_02133 1.6e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
CDOLBINB_02134 6.3e-41 S YCII-related domain
CDOLBINB_02136 1e-212 S response regulator aspartate phosphatase
CDOLBINB_02137 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
CDOLBINB_02138 2.3e-78 yjoA S DinB family
CDOLBINB_02139 7.4e-130 MA20_18170 S membrane transporter protein
CDOLBINB_02140 8.7e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
CDOLBINB_02141 2.7e-282 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
CDOLBINB_02142 5.2e-184 exuR K transcriptional
CDOLBINB_02143 2.4e-226 exuT G Sugar (and other) transporter
CDOLBINB_02144 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CDOLBINB_02145 1.3e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
CDOLBINB_02146 7.7e-191 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
CDOLBINB_02147 3.5e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
CDOLBINB_02148 1.3e-246 yjmB G symporter YjmB
CDOLBINB_02149 9.7e-277 uxaC 5.3.1.12 G glucuronate isomerase
CDOLBINB_02150 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
CDOLBINB_02151 7.1e-66 yjlC S Protein of unknown function (DUF1641)
CDOLBINB_02152 3.4e-91 yjlB S Cupin domain
CDOLBINB_02153 2.8e-174 yjlA EG Putative multidrug resistance efflux transporter
CDOLBINB_02154 2e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
CDOLBINB_02155 1.9e-122 ybbM S transport system, permease component
CDOLBINB_02156 1.2e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
CDOLBINB_02157 8.2e-30
CDOLBINB_02158 2.2e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CDOLBINB_02159 9.5e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
CDOLBINB_02161 1.5e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
CDOLBINB_02162 8.7e-07 S Domain of unknown function (DUF4352)
CDOLBINB_02163 4.3e-95 yjgD S Protein of unknown function (DUF1641)
CDOLBINB_02164 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
CDOLBINB_02165 2e-103 yjgB S Domain of unknown function (DUF4309)
CDOLBINB_02166 1.2e-45 T PhoQ Sensor
CDOLBINB_02167 1.4e-130 yjfC O Predicted Zn-dependent protease (DUF2268)
CDOLBINB_02168 3.9e-13 yjfC O Predicted Zn-dependent protease (DUF2268)
CDOLBINB_02169 2.3e-20 yjfB S Putative motility protein
CDOLBINB_02170 5.5e-83 S Protein of unknown function (DUF2690)
CDOLBINB_02171 6e-263 xynD 3.5.1.104 G Polysaccharide deacetylase
CDOLBINB_02173 3.1e-173 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CDOLBINB_02174 3.9e-51 yjdJ S Domain of unknown function (DUF4306)
CDOLBINB_02175 4.2e-29 S Domain of unknown function (DUF4177)
CDOLBINB_02176 3e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDOLBINB_02178 2.2e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
CDOLBINB_02179 1.3e-48 yjdF S Protein of unknown function (DUF2992)
CDOLBINB_02180 3.3e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
CDOLBINB_02181 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
CDOLBINB_02182 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
CDOLBINB_02184 5.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
CDOLBINB_02185 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
CDOLBINB_02188 1.5e-47 yjcN
CDOLBINB_02189 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
CDOLBINB_02190 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CDOLBINB_02191 3.3e-49 yazA L endonuclease containing a URI domain
CDOLBINB_02192 3.6e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
CDOLBINB_02193 4.8e-31 yabA L Involved in initiation control of chromosome replication
CDOLBINB_02194 6.1e-146 yaaT S stage 0 sporulation protein
CDOLBINB_02195 1.1e-181 holB 2.7.7.7 L DNA polymerase III
CDOLBINB_02196 1.5e-71 yaaR S protein conserved in bacteria
CDOLBINB_02197 2.2e-54 yaaQ S protein conserved in bacteria
CDOLBINB_02198 1.2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDOLBINB_02199 2.1e-271 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
CDOLBINB_02200 4.9e-202 yaaN P Belongs to the TelA family
CDOLBINB_02201 3.4e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
CDOLBINB_02202 3.4e-31 csfB S Inhibitor of sigma-G Gin
CDOLBINB_02203 2.6e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
CDOLBINB_02204 6.3e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
CDOLBINB_02205 1.7e-111 yhfK GM NmrA-like family
CDOLBINB_02206 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
CDOLBINB_02207 1.3e-64 yhfM
CDOLBINB_02208 9e-237 yhfN 3.4.24.84 O Peptidase M48
CDOLBINB_02209 1.1e-196 aprE 3.4.21.62 O Belongs to the peptidase S8 family
CDOLBINB_02210 3.9e-78 VY92_01935 K acetyltransferase
CDOLBINB_02211 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
CDOLBINB_02212 2.1e-158 yfmC M Periplasmic binding protein
CDOLBINB_02213 1.2e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
CDOLBINB_02214 7.7e-197 vraB 2.3.1.9 I Belongs to the thiolase family
CDOLBINB_02215 1.5e-277 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
CDOLBINB_02216 5e-91 bioY S BioY family
CDOLBINB_02217 6.3e-182 hemAT NT chemotaxis protein
CDOLBINB_02218 1.4e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
CDOLBINB_02219 4.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CDOLBINB_02220 1.3e-32 yhzC S IDEAL
CDOLBINB_02221 4.2e-109 comK K Competence transcription factor
CDOLBINB_02222 6.2e-168 IQ Enoyl-(Acyl carrier protein) reductase
CDOLBINB_02223 8.1e-39 yhjA S Excalibur calcium-binding domain
CDOLBINB_02224 2.8e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDOLBINB_02225 6.9e-27 yhjC S Protein of unknown function (DUF3311)
CDOLBINB_02226 6.7e-60 yhjD
CDOLBINB_02227 9.1e-110 yhjE S SNARE associated Golgi protein
CDOLBINB_02228 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
CDOLBINB_02229 6.3e-57
CDOLBINB_02230 6e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CDOLBINB_02231 1.7e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
CDOLBINB_02232 5.2e-75 yfmK 2.3.1.128 K acetyltransferase
CDOLBINB_02233 1.4e-187 yfmJ S N-terminal domain of oxidoreductase
CDOLBINB_02234 5.7e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
CDOLBINB_02235 4.7e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDOLBINB_02236 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDOLBINB_02237 8.5e-168 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
CDOLBINB_02238 2.9e-24 S Protein of unknown function (DUF3212)
CDOLBINB_02239 7.6e-58 yflT S Heat induced stress protein YflT
CDOLBINB_02240 8.5e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
CDOLBINB_02241 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
CDOLBINB_02242 3.7e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CDOLBINB_02243 2.2e-117 citT T response regulator
CDOLBINB_02244 6.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
CDOLBINB_02245 8.5e-227 citM C Citrate transporter
CDOLBINB_02246 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
CDOLBINB_02247 5.6e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CDOLBINB_02248 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CDOLBINB_02249 6.4e-122 yflK S protein conserved in bacteria
CDOLBINB_02250 8.9e-18 yflJ S Protein of unknown function (DUF2639)
CDOLBINB_02251 4.1e-19 yflI
CDOLBINB_02252 2.4e-50 yflH S Protein of unknown function (DUF3243)
CDOLBINB_02253 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
CDOLBINB_02254 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
CDOLBINB_02255 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CDOLBINB_02256 6e-67 yhdN S Domain of unknown function (DUF1992)
CDOLBINB_02257 2.2e-252 agcS_1 E Sodium alanine symporter
CDOLBINB_02258 1.2e-191 E Spore germination protein
CDOLBINB_02260 2.5e-206 yfkR S spore germination
CDOLBINB_02261 1.3e-282 yfkQ EG Spore germination protein
CDOLBINB_02262 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CDOLBINB_02263 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CDOLBINB_02264 4.8e-131 treR K transcriptional
CDOLBINB_02265 1.1e-124 yfkO C nitroreductase
CDOLBINB_02266 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CDOLBINB_02267 4.3e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
CDOLBINB_02268 6.8e-207 ydiM EGP Major facilitator Superfamily
CDOLBINB_02269 1.3e-28 yfkK S Belongs to the UPF0435 family
CDOLBINB_02270 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDOLBINB_02271 1.1e-42 yfkI S gas vesicle protein
CDOLBINB_02272 1.3e-143 yihY S Belongs to the UPF0761 family
CDOLBINB_02273 5e-08
CDOLBINB_02274 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
CDOLBINB_02275 6.7e-182 cax P COG0387 Ca2 H antiporter
CDOLBINB_02276 4.5e-146 yfkD S YfkD-like protein
CDOLBINB_02277 6e-149 yfkC M Mechanosensitive ion channel
CDOLBINB_02278 5.4e-222 yfkA S YfkB-like domain
CDOLBINB_02279 1.1e-26 yfjT
CDOLBINB_02280 2.6e-154 pdaA G deacetylase
CDOLBINB_02281 4.4e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
CDOLBINB_02282 1.7e-184 corA P Mediates influx of magnesium ions
CDOLBINB_02283 6.5e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CDOLBINB_02284 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDOLBINB_02285 3.9e-44 S YfzA-like protein
CDOLBINB_02286 1.8e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDOLBINB_02287 8.4e-81 yfjM S Psort location Cytoplasmic, score
CDOLBINB_02288 1.3e-27 yfjL
CDOLBINB_02289 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CDOLBINB_02290 3.8e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CDOLBINB_02291 9.6e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CDOLBINB_02292 1.6e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CDOLBINB_02293 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
CDOLBINB_02294 1.2e-25 sspH S Belongs to the SspH family
CDOLBINB_02295 4e-56 yfjF S UPF0060 membrane protein
CDOLBINB_02296 3.6e-78 S Family of unknown function (DUF5381)
CDOLBINB_02297 1.8e-101 yfjD S Family of unknown function (DUF5381)
CDOLBINB_02298 5.3e-144 yfjC
CDOLBINB_02299 3.5e-190 yfjB
CDOLBINB_02300 1.1e-44 yfjA S Belongs to the WXG100 family
CDOLBINB_02301 1.6e-260 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CDOLBINB_02302 6.7e-139 glvR K Helix-turn-helix domain, rpiR family
CDOLBINB_02303 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CDOLBINB_02304 9.3e-306 yfiB3 V ABC transporter
CDOLBINB_02305 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
CDOLBINB_02306 9.8e-65 mhqP S DoxX
CDOLBINB_02307 3.5e-160 yfiE 1.13.11.2 S glyoxalase
CDOLBINB_02308 2e-187 yxjM T Histidine kinase
CDOLBINB_02309 2.8e-109 KT LuxR family transcriptional regulator
CDOLBINB_02310 1.7e-168 V ABC transporter, ATP-binding protein
CDOLBINB_02311 1.8e-207 V ABC-2 family transporter protein
CDOLBINB_02312 3.6e-205 V COG0842 ABC-type multidrug transport system, permease component
CDOLBINB_02313 8.3e-99 padR K transcriptional
CDOLBINB_02314 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
CDOLBINB_02315 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CDOLBINB_02316 4.7e-99 yfiT S Belongs to the metal hydrolase YfiT family
CDOLBINB_02317 1e-282 yfiU EGP Major facilitator Superfamily
CDOLBINB_02318 4.9e-79 yfiV K transcriptional
CDOLBINB_02319 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CDOLBINB_02320 2.8e-174 yfiY P ABC transporter substrate-binding protein
CDOLBINB_02321 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDOLBINB_02322 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDOLBINB_02323 4.5e-163 yfhB 5.3.3.17 S PhzF family
CDOLBINB_02324 4.4e-106 yfhC C nitroreductase
CDOLBINB_02325 2.1e-25 yfhD S YfhD-like protein
CDOLBINB_02327 2.1e-171 yfhF S nucleoside-diphosphate sugar epimerase
CDOLBINB_02328 4.3e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
CDOLBINB_02329 9.7e-52 yfhH S Protein of unknown function (DUF1811)
CDOLBINB_02331 4.3e-209 yfhI EGP Major facilitator Superfamily
CDOLBINB_02332 6.2e-20 sspK S reproduction
CDOLBINB_02333 1.3e-44 yfhJ S WVELL protein
CDOLBINB_02334 1.1e-89 batE T Bacterial SH3 domain homologues
CDOLBINB_02335 1e-47 yfhL S SdpI/YhfL protein family
CDOLBINB_02336 1.3e-170 yfhM S Alpha beta hydrolase
CDOLBINB_02337 8e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CDOLBINB_02338 0.0 yfhO S Bacterial membrane protein YfhO
CDOLBINB_02339 1.2e-185 yfhP S membrane-bound metal-dependent
CDOLBINB_02340 1.1e-210 mutY L A G-specific
CDOLBINB_02341 5.7e-27 yfhS
CDOLBINB_02342 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CDOLBINB_02343 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
CDOLBINB_02344 3.3e-37 ygaB S YgaB-like protein
CDOLBINB_02345 3.7e-104 ygaC J Belongs to the UPF0374 family
CDOLBINB_02346 1.8e-301 ygaD V ABC transporter
CDOLBINB_02347 8.7e-180 ygaE S Membrane
CDOLBINB_02348 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
CDOLBINB_02349 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
CDOLBINB_02350 4e-80 perR P Belongs to the Fur family
CDOLBINB_02351 2.8e-55 ygzB S UPF0295 protein
CDOLBINB_02352 6.7e-167 ygxA S Nucleotidyltransferase-like
CDOLBINB_02353 2.7e-31 yozC
CDOLBINB_02354 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
CDOLBINB_02355 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
CDOLBINB_02356 6e-165 sodA 1.15.1.1 P Superoxide dismutase
CDOLBINB_02357 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CDOLBINB_02358 5.6e-167 yocS S -transporter
CDOLBINB_02359 5.3e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
CDOLBINB_02360 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
CDOLBINB_02361 0.0 yojO P Von Willebrand factor
CDOLBINB_02362 7.2e-161 yojN S ATPase family associated with various cellular activities (AAA)
CDOLBINB_02363 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDOLBINB_02364 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CDOLBINB_02365 2.6e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
CDOLBINB_02366 4.9e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CDOLBINB_02368 5.2e-243 norM V Multidrug efflux pump
CDOLBINB_02369 7.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CDOLBINB_02370 2.1e-125 yojG S deacetylase
CDOLBINB_02371 2.2e-60 yojF S Protein of unknown function (DUF1806)
CDOLBINB_02372 1.6e-42
CDOLBINB_02373 5.6e-161 rarD S -transporter
CDOLBINB_02374 8.6e-65 yozR S COG0071 Molecular chaperone (small heat shock protein)
CDOLBINB_02375 2.6e-09
CDOLBINB_02376 1.4e-205 gntP EG COG2610 H gluconate symporter and related permeases
CDOLBINB_02377 8e-64 yodA S tautomerase
CDOLBINB_02378 4.4e-55 yodB K transcriptional
CDOLBINB_02379 1.4e-107 yodC C nitroreductase
CDOLBINB_02380 3.8e-113 mhqD S Carboxylesterase
CDOLBINB_02381 8.4e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
CDOLBINB_02382 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
CDOLBINB_02383 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
CDOLBINB_02384 6.1e-224 acuC BQ histone deacetylase
CDOLBINB_02385 1.4e-125 motS N Flagellar motor protein
CDOLBINB_02386 4.6e-146 motA N flagellar motor
CDOLBINB_02387 1.7e-182 ccpA K catabolite control protein A
CDOLBINB_02388 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
CDOLBINB_02389 1.7e-54 ytxJ O Protein of unknown function (DUF2847)
CDOLBINB_02390 6.6e-17 ytxH S COG4980 Gas vesicle protein
CDOLBINB_02391 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CDOLBINB_02392 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CDOLBINB_02393 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
CDOLBINB_02394 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CDOLBINB_02395 9.8e-149 ytpQ S Belongs to the UPF0354 family
CDOLBINB_02396 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CDOLBINB_02397 1e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
CDOLBINB_02398 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
CDOLBINB_02399 2.2e-51 ytzB S small secreted protein
CDOLBINB_02400 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
CDOLBINB_02401 3.5e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
CDOLBINB_02402 2.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CDOLBINB_02403 2e-45 ytzH S YtzH-like protein
CDOLBINB_02404 1.8e-150 ytmP 2.7.1.89 M Phosphotransferase
CDOLBINB_02405 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
CDOLBINB_02406 2.5e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
CDOLBINB_02407 1.3e-165 ytlQ
CDOLBINB_02408 8.9e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CDOLBINB_02409 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CDOLBINB_02410 2.7e-271 pepV 3.5.1.18 E Dipeptidase
CDOLBINB_02411 7.2e-226 pbuO S permease
CDOLBINB_02412 9.3e-201 ythQ U Bacterial ABC transporter protein EcsB
CDOLBINB_02413 4.8e-131 ythP V ABC transporter
CDOLBINB_02414 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
CDOLBINB_02415 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CDOLBINB_02416 6.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CDOLBINB_02417 2.6e-230 ytfP S HI0933-like protein
CDOLBINB_02418 6.4e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
CDOLBINB_02419 3.1e-26 yteV S Sporulation protein Cse60
CDOLBINB_02420 1.3e-114 yteU S Integral membrane protein
CDOLBINB_02421 5e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
CDOLBINB_02422 3.9e-72 yteS G transport
CDOLBINB_02423 1.5e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
CDOLBINB_02424 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
CDOLBINB_02425 0.0 ytdP K Transcriptional regulator
CDOLBINB_02426 5.2e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
CDOLBINB_02427 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
CDOLBINB_02428 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
CDOLBINB_02429 3.5e-219 bioI 1.14.14.46 C Cytochrome P450
CDOLBINB_02430 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDOLBINB_02431 7.2e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CDOLBINB_02432 5.1e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CDOLBINB_02433 7.9e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
CDOLBINB_02434 3.8e-139 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
CDOLBINB_02435 9.2e-172 ytaP S Acetyl xylan esterase (AXE1)
CDOLBINB_02436 2.7e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
CDOLBINB_02437 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
CDOLBINB_02438 2e-84 gerD
CDOLBINB_02439 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
CDOLBINB_02440 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CDOLBINB_02441 9.7e-66 ybaK S Protein of unknown function (DUF2521)
CDOLBINB_02442 3.4e-143 ybaJ Q Methyltransferase domain
CDOLBINB_02443 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
CDOLBINB_02444 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDOLBINB_02445 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CDOLBINB_02446 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CDOLBINB_02447 7.5e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CDOLBINB_02448 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CDOLBINB_02449 3.6e-58 rplQ J Ribosomal protein L17
CDOLBINB_02450 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDOLBINB_02451 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDOLBINB_02452 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDOLBINB_02453 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CDOLBINB_02454 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDOLBINB_02455 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
CDOLBINB_02456 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CDOLBINB_02457 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CDOLBINB_02458 1.8e-72 rplO J binds to the 23S rRNA
CDOLBINB_02459 1.9e-23 rpmD J Ribosomal protein L30
CDOLBINB_02460 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDOLBINB_02461 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDOLBINB_02462 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDOLBINB_02463 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDOLBINB_02464 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDOLBINB_02465 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDOLBINB_02466 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CDOLBINB_02467 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDOLBINB_02468 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDOLBINB_02469 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
CDOLBINB_02470 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDOLBINB_02471 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDOLBINB_02472 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDOLBINB_02473 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDOLBINB_02474 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDOLBINB_02475 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CDOLBINB_02476 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
CDOLBINB_02477 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDOLBINB_02478 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
CDOLBINB_02479 2e-180 ybaC 3.4.11.5 S Alpha/beta hydrolase family
CDOLBINB_02480 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDOLBINB_02481 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDOLBINB_02482 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CDOLBINB_02483 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDOLBINB_02484 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
CDOLBINB_02485 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDOLBINB_02486 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDOLBINB_02487 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
CDOLBINB_02488 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CDOLBINB_02489 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDOLBINB_02490 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CDOLBINB_02491 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDOLBINB_02492 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
CDOLBINB_02493 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CDOLBINB_02494 4.4e-115 sigH K Belongs to the sigma-70 factor family
CDOLBINB_02495 1.2e-88 yacP S RNA-binding protein containing a PIN domain
CDOLBINB_02496 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDOLBINB_02497 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CDOLBINB_02498 1.6e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CDOLBINB_02499 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
CDOLBINB_02500 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDOLBINB_02501 3.5e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
CDOLBINB_02502 3.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
CDOLBINB_02503 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
CDOLBINB_02504 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CDOLBINB_02505 2.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CDOLBINB_02506 0.0 clpC O Belongs to the ClpA ClpB family
CDOLBINB_02507 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
CDOLBINB_02508 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
CDOLBINB_02509 2.9e-76 ctsR K Belongs to the CtsR family
CDOLBINB_02510 8.3e-13 yxiG
CDOLBINB_02511 1e-135
CDOLBINB_02512 3.9e-30 yxiI S Protein of unknown function (DUF2716)
CDOLBINB_02513 4.4e-45 yxiI S Protein of unknown function (DUF2716)
CDOLBINB_02514 7.7e-43 yxiJ S YxiJ-like protein
CDOLBINB_02517 8e-213 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
CDOLBINB_02518 3.9e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
CDOLBINB_02519 5.6e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
CDOLBINB_02520 1.8e-111
CDOLBINB_02521 8.3e-151 licT K transcriptional antiterminator
CDOLBINB_02522 7.3e-143 exoK GH16 M licheninase activity
CDOLBINB_02523 1.9e-223 citH C Citrate transporter
CDOLBINB_02524 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
CDOLBINB_02525 3e-47 yxiS
CDOLBINB_02526 2.6e-102 T Domain of unknown function (DUF4163)
CDOLBINB_02527 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CDOLBINB_02529 4.1e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
CDOLBINB_02531 1.7e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDOLBINB_02532 6.1e-255 iolT EGP Major facilitator Superfamily
CDOLBINB_02533 1.7e-111 yokF 3.1.31.1 L RNA catabolic process
CDOLBINB_02534 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
CDOLBINB_02535 4.4e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
CDOLBINB_02536 2.8e-213 xylR GK ROK family
CDOLBINB_02537 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
CDOLBINB_02538 2.3e-254 xynT G MFS/sugar transport protein
CDOLBINB_02539 2.4e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
CDOLBINB_02541 1.3e-56 ynaF
CDOLBINB_02542 5.6e-123 ynaE S Domain of unknown function (DUF3885)
CDOLBINB_02543 1.2e-96 ynaD J Acetyltransferase (GNAT) domain
CDOLBINB_02545 3.7e-79 G SMI1-KNR4 cell-wall
CDOLBINB_02546 2.1e-36
CDOLBINB_02547 1.7e-124
CDOLBINB_02548 5.1e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CDOLBINB_02549 1.7e-122 ywrJ
CDOLBINB_02550 1.2e-123 cotB
CDOLBINB_02551 6.2e-207 cotH M Spore Coat
CDOLBINB_02552 2.4e-13
CDOLBINB_02553 5.3e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDOLBINB_02554 2.5e-53 S Domain of unknown function (DUF4181)
CDOLBINB_02555 5.7e-302 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
CDOLBINB_02556 8e-82 ywrC K Transcriptional regulator
CDOLBINB_02557 1.2e-103 ywrB P Chromate transporter
CDOLBINB_02558 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
CDOLBINB_02559 1.1e-116 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
CDOLBINB_02560 1.7e-25
CDOLBINB_02561 8.7e-241 ywqJ S Pre-toxin TG
CDOLBINB_02562 3.1e-38 ywqI S Family of unknown function (DUF5344)
CDOLBINB_02563 1e-19 S Domain of unknown function (DUF5082)
CDOLBINB_02564 9.8e-154 ywqG S Domain of unknown function (DUF1963)
CDOLBINB_02565 5.2e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDOLBINB_02566 2.5e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
CDOLBINB_02567 2.2e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
CDOLBINB_02568 2e-116 ywqC M biosynthesis protein
CDOLBINB_02569 1.2e-17
CDOLBINB_02570 1.3e-306 ywqB S SWIM zinc finger
CDOLBINB_02571 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
CDOLBINB_02572 4.8e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
CDOLBINB_02573 3.4e-138 glcR K COG1349 Transcriptional regulators of sugar metabolism
CDOLBINB_02574 3.7e-57 ssbB L Single-stranded DNA-binding protein
CDOLBINB_02575 1.3e-66 ywpG
CDOLBINB_02576 1.1e-66 ywpF S YwpF-like protein
CDOLBINB_02577 6.7e-84 srtA 3.4.22.70 M Sortase family
CDOLBINB_02578 0.0 M1-568 M cell wall anchor domain
CDOLBINB_02579 3.1e-174 M1-574 T Transcriptional regulatory protein, C terminal
CDOLBINB_02580 0.0 ywpD T PhoQ Sensor
CDOLBINB_02581 1.3e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CDOLBINB_02582 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CDOLBINB_02583 2e-197 S aspartate phosphatase
CDOLBINB_02584 7.5e-141 flhP N flagellar basal body
CDOLBINB_02585 1.5e-125 flhO N flagellar basal body
CDOLBINB_02586 3.5e-180 mbl D Rod shape-determining protein
CDOLBINB_02587 3e-44 spoIIID K Stage III sporulation protein D
CDOLBINB_02588 2.1e-70 ywoH K COG1846 Transcriptional regulators
CDOLBINB_02589 2.7e-211 ywoG EGP Major facilitator Superfamily
CDOLBINB_02590 3.6e-231 ywoF P Right handed beta helix region
CDOLBINB_02591 7.5e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
CDOLBINB_02592 9.8e-242 ywoD EGP Major facilitator superfamily
CDOLBINB_02593 1.5e-103 phzA Q Isochorismatase family
CDOLBINB_02594 7.5e-77
CDOLBINB_02595 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CDOLBINB_02597 8.5e-23 yuzC
CDOLBINB_02598 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
CDOLBINB_02599 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDOLBINB_02600 2.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
CDOLBINB_02601 1.8e-66 yueI S Protein of unknown function (DUF1694)
CDOLBINB_02602 7.4e-39 yueH S YueH-like protein
CDOLBINB_02603 6.6e-31 yueG S Spore germination protein gerPA/gerPF
CDOLBINB_02604 3.2e-190 yueF S transporter activity
CDOLBINB_02605 3.4e-70 S Protein of unknown function (DUF2283)
CDOLBINB_02606 2.9e-24 S Protein of unknown function (DUF2642)
CDOLBINB_02607 4.8e-96 yueE S phosphohydrolase
CDOLBINB_02608 4.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CDOLBINB_02609 4.3e-64 yueC S Family of unknown function (DUF5383)
CDOLBINB_02610 0.0 esaA S type VII secretion protein EsaA
CDOLBINB_02611 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
CDOLBINB_02612 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
CDOLBINB_02613 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
CDOLBINB_02614 2.8e-45 esxA S Belongs to the WXG100 family
CDOLBINB_02615 4.7e-227 yukF QT Transcriptional regulator
CDOLBINB_02616 5.2e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
CDOLBINB_02617 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
CDOLBINB_02618 5e-36 mbtH S MbtH-like protein
CDOLBINB_02619 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CDOLBINB_02620 3.1e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
CDOLBINB_02621 1.6e-310 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
CDOLBINB_02622 6.6e-226 entC 5.4.4.2 HQ Isochorismate synthase
CDOLBINB_02623 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CDOLBINB_02624 5.6e-166 besA S Putative esterase
CDOLBINB_02625 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
CDOLBINB_02626 9.7e-93 bioY S Biotin biosynthesis protein
CDOLBINB_02627 3.9e-211 yuiF S antiporter
CDOLBINB_02628 9.3e-278 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDOLBINB_02629 1.2e-77 yuiD S protein conserved in bacteria
CDOLBINB_02630 1.4e-116 yuiC S protein conserved in bacteria
CDOLBINB_02631 1.9e-26 yuiB S Putative membrane protein
CDOLBINB_02632 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
CDOLBINB_02633 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
CDOLBINB_02635 2.1e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CDOLBINB_02636 5e-116 paiB K Putative FMN-binding domain
CDOLBINB_02637 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CDOLBINB_02638 3.7e-63 erpA S Belongs to the HesB IscA family
CDOLBINB_02639 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDOLBINB_02640 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CDOLBINB_02641 3.2e-39 yuzB S Belongs to the UPF0349 family
CDOLBINB_02642 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
CDOLBINB_02643 1.1e-55 yuzD S protein conserved in bacteria
CDOLBINB_02644 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
CDOLBINB_02645 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
CDOLBINB_02646 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CDOLBINB_02647 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDOLBINB_02648 7.9e-241 hom 1.1.1.3 E homoserine dehydrogenase
CDOLBINB_02649 1.4e-197 yutH S Spore coat protein
CDOLBINB_02650 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
CDOLBINB_02651 4.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CDOLBINB_02652 1e-75 yutE S Protein of unknown function DUF86
CDOLBINB_02653 9.7e-48 yutD S protein conserved in bacteria
CDOLBINB_02654 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CDOLBINB_02655 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDOLBINB_02656 4.5e-196 lytH M Peptidase, M23
CDOLBINB_02657 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
CDOLBINB_02658 1.1e-47 yunC S Domain of unknown function (DUF1805)
CDOLBINB_02659 1.6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CDOLBINB_02660 2e-141 yunE S membrane transporter protein
CDOLBINB_02661 4.3e-171 yunF S Protein of unknown function DUF72
CDOLBINB_02662 8.2e-60 yunG
CDOLBINB_02663 6.6e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
CDOLBINB_02664 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
CDOLBINB_02665 6.3e-233 pbuX F Permease family
CDOLBINB_02666 4.8e-222 pbuX F xanthine
CDOLBINB_02667 7.5e-280 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
CDOLBINB_02668 3.5e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
CDOLBINB_02670 3.4e-94 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
CDOLBINB_02671 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
CDOLBINB_02672 1.9e-147 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
CDOLBINB_02673 2.6e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
CDOLBINB_02674 7.2e-186 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDOLBINB_02675 2.5e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
CDOLBINB_02676 1.7e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
CDOLBINB_02677 3.5e-168 bsn L Ribonuclease
CDOLBINB_02678 8.5e-204 msmX P Belongs to the ABC transporter superfamily
CDOLBINB_02679 3.3e-135 yurK K UTRA
CDOLBINB_02680 5.7e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
CDOLBINB_02681 1.6e-168 yurM P COG0395 ABC-type sugar transport system, permease component
CDOLBINB_02682 1.2e-155 yurN G Binding-protein-dependent transport system inner membrane component
CDOLBINB_02683 7.2e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
CDOLBINB_02684 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
CDOLBINB_02685 8.2e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
CDOLBINB_02686 1.4e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
CDOLBINB_02688 1e-41
CDOLBINB_02689 1.9e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CDOLBINB_02690 3.5e-271 sufB O FeS cluster assembly
CDOLBINB_02691 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
CDOLBINB_02692 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDOLBINB_02693 4.5e-244 sufD O assembly protein SufD
CDOLBINB_02694 1.5e-141 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CDOLBINB_02695 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDOLBINB_02696 1.4e-145 metQ P Belongs to the NlpA lipoprotein family
CDOLBINB_02697 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
CDOLBINB_02698 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDOLBINB_02699 2.4e-56 yusD S SCP-2 sterol transfer family
CDOLBINB_02700 5.6e-55 traF CO Thioredoxin
CDOLBINB_02701 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
CDOLBINB_02702 1.1e-39 yusG S Protein of unknown function (DUF2553)
CDOLBINB_02703 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
CDOLBINB_02704 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
CDOLBINB_02705 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
CDOLBINB_02706 2.7e-216 fadA 2.3.1.16 I Belongs to the thiolase family
CDOLBINB_02707 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
CDOLBINB_02708 8.1e-09 S YuzL-like protein
CDOLBINB_02709 2.3e-162 fadM E Proline dehydrogenase
CDOLBINB_02710 5.1e-40
CDOLBINB_02711 5.4e-53 yusN M Coat F domain
CDOLBINB_02712 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
CDOLBINB_02713 1.1e-292 yusP P Major facilitator superfamily
CDOLBINB_02714 2.7e-64 yusQ S Tautomerase enzyme
CDOLBINB_02715 2.6e-108 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CDOLBINB_02716 5.7e-158 yusT K LysR substrate binding domain
CDOLBINB_02717 5.6e-39 yusU S Protein of unknown function (DUF2573)
CDOLBINB_02718 1e-153 yusV 3.6.3.34 HP ABC transporter
CDOLBINB_02719 2.5e-66 S YusW-like protein
CDOLBINB_02720 1.8e-299 pepF2 E COG1164 Oligoendopeptidase F
CDOLBINB_02721 1.7e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CDOLBINB_02722 1.8e-78 dps P Ferritin-like domain
CDOLBINB_02723 6.2e-236 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDOLBINB_02724 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CDOLBINB_02725 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
CDOLBINB_02726 4.3e-158 yuxN K Transcriptional regulator
CDOLBINB_02727 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CDOLBINB_02728 2.3e-24 S Protein of unknown function (DUF3970)
CDOLBINB_02729 2.4e-246 gerAA EG Spore germination protein
CDOLBINB_02730 3.8e-196 gerAB E Spore germination protein
CDOLBINB_02731 2.9e-183 gerAC S Spore germination B3/ GerAC like, C-terminal
CDOLBINB_02732 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CDOLBINB_02733 4.6e-186 vraS 2.7.13.3 T Histidine kinase
CDOLBINB_02734 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
CDOLBINB_02735 1.8e-127 liaG S Putative adhesin
CDOLBINB_02736 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
CDOLBINB_02737 5.6e-62 liaI S membrane
CDOLBINB_02738 5.9e-225 yvqJ EGP Major facilitator Superfamily
CDOLBINB_02739 1.6e-100 yvqK 2.5.1.17 S Adenosyltransferase
CDOLBINB_02740 8.6e-243 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
CDOLBINB_02741 9.4e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDOLBINB_02742 1e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
CDOLBINB_02743 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CDOLBINB_02744 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
CDOLBINB_02745 0.0 T PhoQ Sensor
CDOLBINB_02746 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CDOLBINB_02747 9.4e-23
CDOLBINB_02748 1.9e-98 yvrI K RNA polymerase
CDOLBINB_02749 2.4e-19 S YvrJ protein family
CDOLBINB_02750 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
CDOLBINB_02751 1.3e-64 yvrL S Regulatory protein YrvL
CDOLBINB_02752 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
CDOLBINB_02753 2.3e-122 macB V ABC transporter, ATP-binding protein
CDOLBINB_02754 4.8e-176 M Efflux transporter rnd family, mfp subunit
CDOLBINB_02755 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
CDOLBINB_02756 6.9e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDOLBINB_02757 3e-182 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDOLBINB_02758 2.6e-177 fhuD P ABC transporter
CDOLBINB_02759 4.9e-236 yvsH E Arginine ornithine antiporter
CDOLBINB_02760 6.5e-16 S Small spore protein J (Spore_SspJ)
CDOLBINB_02761 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
CDOLBINB_02762 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CDOLBINB_02763 8.3e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
CDOLBINB_02764 1e-134 modA P COG0725 ABC-type molybdate transport system, periplasmic component
CDOLBINB_02765 4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
CDOLBINB_02766 5.9e-157 yvgN S reductase
CDOLBINB_02767 2.1e-85 yvgO
CDOLBINB_02768 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
CDOLBINB_02769 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
CDOLBINB_02770 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDOLBINB_02771 0.0 helD 3.6.4.12 L DNA helicase
CDOLBINB_02773 1.6e-106 yvgT S membrane
CDOLBINB_02774 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
CDOLBINB_02775 1.6e-104 bdbD O Thioredoxin
CDOLBINB_02776 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
CDOLBINB_02777 0.0 copA 3.6.3.54 P P-type ATPase
CDOLBINB_02778 5.9e-29 copZ P Copper resistance protein CopZ
CDOLBINB_02779 2.2e-48 csoR S transcriptional
CDOLBINB_02780 1.9e-192 yvaA 1.1.1.371 S Oxidoreductase
CDOLBINB_02781 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDOLBINB_02782 0.0 yvaC S Fusaric acid resistance protein-like
CDOLBINB_02783 9.7e-73 yvaD S Family of unknown function (DUF5360)
CDOLBINB_02784 1.8e-54 yvaE P Small Multidrug Resistance protein
CDOLBINB_02785 3.3e-98 K Bacterial regulatory proteins, tetR family
CDOLBINB_02786 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CDOLBINB_02787 2.4e-15
CDOLBINB_02790 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDOLBINB_02791 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CDOLBINB_02792 5.6e-143 est 3.1.1.1 S Carboxylesterase
CDOLBINB_02793 2.4e-23 secG U Preprotein translocase subunit SecG
CDOLBINB_02794 8.2e-153 yvaM S Serine aminopeptidase, S33
CDOLBINB_02795 7.5e-36 yvzC K Transcriptional
CDOLBINB_02796 9.8e-68 K transcriptional
CDOLBINB_02797 1.2e-68 yvaO K Cro/C1-type HTH DNA-binding domain
CDOLBINB_02798 2.2e-54 yodB K transcriptional
CDOLBINB_02799 3.8e-219 NT chemotaxis protein
CDOLBINB_02804 7.8e-08
CDOLBINB_02812 2e-08
CDOLBINB_02816 5e-142 spo0M S COG4326 Sporulation control protein
CDOLBINB_02817 1.2e-26
CDOLBINB_02818 1.8e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
CDOLBINB_02819 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDOLBINB_02821 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
CDOLBINB_02822 5.1e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
CDOLBINB_02823 5.6e-170 ssuA M Sulfonate ABC transporter
CDOLBINB_02824 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CDOLBINB_02825 9e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
CDOLBINB_02827 8.6e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDOLBINB_02828 5.5e-75 ygaO
CDOLBINB_02829 4.4e-29 K Transcriptional regulator
CDOLBINB_02831 3.3e-112 yhzB S B3/4 domain
CDOLBINB_02832 3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDOLBINB_02833 3.7e-176 yhbB S Putative amidase domain
CDOLBINB_02834 1.8e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CDOLBINB_02835 1.2e-109 yhbD K Protein of unknown function (DUF4004)
CDOLBINB_02836 1.7e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
CDOLBINB_02837 5.9e-73 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
CDOLBINB_02838 0.0 prkA T Ser protein kinase
CDOLBINB_02839 2.5e-225 yhbH S Belongs to the UPF0229 family
CDOLBINB_02840 2.2e-76 yhbI K DNA-binding transcription factor activity
CDOLBINB_02841 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
CDOLBINB_02842 2.9e-269 yhcA EGP Major facilitator Superfamily
CDOLBINB_02843 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
CDOLBINB_02844 2.8e-37 yhcC
CDOLBINB_02845 6e-55
CDOLBINB_02846 6.6e-60 yhcF K Transcriptional regulator
CDOLBINB_02847 4e-122 yhcG V ABC transporter, ATP-binding protein
CDOLBINB_02848 1.9e-164 yhcH V ABC transporter, ATP-binding protein
CDOLBINB_02849 2.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CDOLBINB_02850 1e-30 cspB K Cold-shock protein
CDOLBINB_02851 9.7e-152 metQ M Belongs to the nlpA lipoprotein family
CDOLBINB_02852 4.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
CDOLBINB_02853 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CDOLBINB_02854 8.3e-78 S Protein of unknown function (DUF2812)
CDOLBINB_02855 1.2e-49 K Transcriptional regulator PadR-like family
CDOLBINB_02856 4.1e-40 yhcM
CDOLBINB_02857 2.2e-65 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CDOLBINB_02858 1.2e-153 yhcP
CDOLBINB_02859 5.2e-100 yhcQ M Spore coat protein
CDOLBINB_02860 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
CDOLBINB_02861 3.9e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
CDOLBINB_02862 1.5e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CDOLBINB_02863 9.3e-68 yhcU S Family of unknown function (DUF5365)
CDOLBINB_02864 9.9e-68 yhcV S COG0517 FOG CBS domain
CDOLBINB_02865 1.3e-119 yhcW 5.4.2.6 S hydrolase
CDOLBINB_02866 1.7e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CDOLBINB_02867 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDOLBINB_02868 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CDOLBINB_02869 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
CDOLBINB_02870 3e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDOLBINB_02871 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CDOLBINB_02872 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
CDOLBINB_02873 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
CDOLBINB_02874 2.2e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CDOLBINB_02875 4.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
CDOLBINB_02876 1.2e-38 yhdB S YhdB-like protein
CDOLBINB_02877 1.8e-53 yhdC S Protein of unknown function (DUF3889)
CDOLBINB_02878 1e-183 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CDOLBINB_02879 6e-76 nsrR K Transcriptional regulator
CDOLBINB_02880 2e-235 ygxB M Conserved TM helix
CDOLBINB_02881 6.3e-276 ycgB S Stage V sporulation protein R
CDOLBINB_02882 4.9e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
CDOLBINB_02883 4.3e-225 amt P Ammonium transporter
CDOLBINB_02884 1.6e-58 nrgB K Belongs to the P(II) protein family
CDOLBINB_02885 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
CDOLBINB_02886 3.5e-73 ywnJ S VanZ like family
CDOLBINB_02887 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
CDOLBINB_02888 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
CDOLBINB_02889 2.7e-14 ywnC S Family of unknown function (DUF5362)
CDOLBINB_02890 3.3e-18 ywnF S Family of unknown function (DUF5392)
CDOLBINB_02891 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDOLBINB_02892 5.3e-144 mta K transcriptional
CDOLBINB_02893 1.3e-58 ywnC S Family of unknown function (DUF5362)
CDOLBINB_02894 1.6e-114 ywnB S NAD(P)H-binding
CDOLBINB_02895 1.7e-64 ywnA K Transcriptional regulator
CDOLBINB_02896 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CDOLBINB_02897 8.5e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
CDOLBINB_02898 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
CDOLBINB_02899 3.8e-11 csbD K CsbD-like
CDOLBINB_02900 3.8e-84 ywmF S Peptidase M50
CDOLBINB_02902 4.6e-104 S response regulator aspartate phosphatase
CDOLBINB_02903 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDOLBINB_02904 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDOLBINB_02906 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
CDOLBINB_02907 3.9e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
CDOLBINB_02908 4.6e-175 spoIID D Stage II sporulation protein D
CDOLBINB_02909 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDOLBINB_02910 2.4e-133 ywmB S TATA-box binding
CDOLBINB_02911 1.3e-32 ywzB S membrane
CDOLBINB_02912 4.3e-88 ywmA
CDOLBINB_02913 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CDOLBINB_02914 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDOLBINB_02915 1.9e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDOLBINB_02916 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDOLBINB_02917 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDOLBINB_02918 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDOLBINB_02919 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDOLBINB_02920 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
CDOLBINB_02921 2.5e-62 atpI S ATP synthase
CDOLBINB_02922 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDOLBINB_02923 4.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDOLBINB_02924 7.2e-95 ywlG S Belongs to the UPF0340 family
CDOLBINB_02925 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
CDOLBINB_02926 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDOLBINB_02927 1.7e-91 mntP P Probably functions as a manganese efflux pump
CDOLBINB_02928 6.8e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CDOLBINB_02929 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
CDOLBINB_02930 1.4e-111 spoIIR S stage II sporulation protein R
CDOLBINB_02931 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
CDOLBINB_02933 5.8e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CDOLBINB_02934 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDOLBINB_02935 2.6e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CDOLBINB_02936 6.4e-75 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
CDOLBINB_02937 8.6e-160 ywkB S Membrane transport protein
CDOLBINB_02938 0.0 sfcA 1.1.1.38 C malic enzyme
CDOLBINB_02939 7e-104 tdk 2.7.1.21 F thymidine kinase
CDOLBINB_02940 1.1e-32 rpmE J Binds the 23S rRNA
CDOLBINB_02941 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDOLBINB_02942 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
CDOLBINB_02943 2.8e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDOLBINB_02944 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDOLBINB_02945 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
CDOLBINB_02946 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
CDOLBINB_02947 1.8e-90 ywjG S Domain of unknown function (DUF2529)
CDOLBINB_02948 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CDOLBINB_02949 1.1e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CDOLBINB_02950 1.7e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
CDOLBINB_02951 0.0 fadF C COG0247 Fe-S oxidoreductase
CDOLBINB_02952 2.4e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
CDOLBINB_02953 4.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
CDOLBINB_02954 2.7e-42 ywjC
CDOLBINB_02955 1.1e-95 ywjB H RibD C-terminal domain
CDOLBINB_02956 0.0 ywjA V ABC transporter
CDOLBINB_02957 4.2e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDOLBINB_02958 9.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
CDOLBINB_02959 1.2e-92 narJ 1.7.5.1 C nitrate reductase
CDOLBINB_02960 2.8e-295 narH 1.7.5.1 C Nitrate reductase, beta
CDOLBINB_02961 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CDOLBINB_02962 5.9e-85 arfM T cyclic nucleotide binding
CDOLBINB_02963 1.2e-137 ywiC S YwiC-like protein
CDOLBINB_02964 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
CDOLBINB_02965 1.3e-213 narK P COG2223 Nitrate nitrite transporter
CDOLBINB_02966 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
CDOLBINB_02967 4.7e-73 ywiB S protein conserved in bacteria
CDOLBINB_02968 1.4e-80 ykuV CO thiol-disulfide
CDOLBINB_02969 3.9e-101 ykuU O Alkyl hydroperoxide reductase
CDOLBINB_02970 8.8e-142 ykuT M Mechanosensitive ion channel
CDOLBINB_02971 9e-37 ykuS S Belongs to the UPF0180 family
CDOLBINB_02972 2.1e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CDOLBINB_02973 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CDOLBINB_02974 3.9e-78 fld C Flavodoxin
CDOLBINB_02975 5.7e-174 ykuO
CDOLBINB_02976 5.9e-85 fld C Flavodoxin domain
CDOLBINB_02977 3.5e-168 ccpC K Transcriptional regulator
CDOLBINB_02978 1.6e-76 ykuL S CBS domain
CDOLBINB_02979 3.9e-27 ykzF S Antirepressor AbbA
CDOLBINB_02980 4.4e-94 ykuK S Ribonuclease H-like
CDOLBINB_02981 3.9e-37 ykuJ S protein conserved in bacteria
CDOLBINB_02982 2e-233 ykuI T Diguanylate phosphodiesterase
CDOLBINB_02983 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CDOLBINB_02984 9.4e-166 ykuE S Metallophosphoesterase
CDOLBINB_02985 1.8e-87 ykuD S protein conserved in bacteria
CDOLBINB_02986 2.8e-238 ykuC EGP Major facilitator Superfamily
CDOLBINB_02987 1.7e-84 ykyB S YkyB-like protein
CDOLBINB_02988 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
CDOLBINB_02989 1.3e-15
CDOLBINB_02990 3.3e-222 patA 2.6.1.1 E Aminotransferase
CDOLBINB_02991 0.0 pilS 2.7.13.3 T Histidine kinase
CDOLBINB_02992 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
CDOLBINB_02993 3e-123 ykwD J protein with SCP PR1 domains
CDOLBINB_02994 3.5e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
CDOLBINB_02995 7.3e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
CDOLBINB_02996 4.1e-257 mcpC NT chemotaxis protein
CDOLBINB_02997 2e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CDOLBINB_02998 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
CDOLBINB_02999 7.2e-39 splA S Transcriptional regulator
CDOLBINB_03000 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDOLBINB_03001 2.1e-39 ptsH G phosphocarrier protein HPr
CDOLBINB_03002 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CDOLBINB_03003 5e-127 glcT K antiterminator
CDOLBINB_03005 1.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
CDOLBINB_03006 3.7e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
CDOLBINB_03007 3.8e-09
CDOLBINB_03008 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
CDOLBINB_03009 4.9e-90 stoA CO thiol-disulfide
CDOLBINB_03010 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CDOLBINB_03011 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
CDOLBINB_03012 2.8e-28
CDOLBINB_03013 6e-25 ykvS S protein conserved in bacteria
CDOLBINB_03014 5.6e-46 ykvR S Protein of unknown function (DUF3219)
CDOLBINB_03015 3.1e-162 G Glycosyl hydrolases family 18
CDOLBINB_03016 3.5e-35 3.5.1.104 M LysM domain
CDOLBINB_03017 8.4e-215 ykvP 3.5.1.28 M Glycosyl transferases group 1
CDOLBINB_03018 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
CDOLBINB_03019 1.1e-59 ykvN K HxlR-like helix-turn-helix
CDOLBINB_03020 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDOLBINB_03021 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CDOLBINB_03022 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
CDOLBINB_03023 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDOLBINB_03024 6.2e-180 ykvI S membrane
CDOLBINB_03025 0.0 clpE O Belongs to the ClpA ClpB family
CDOLBINB_03026 1.1e-225 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDOLBINB_03027 1e-10
CDOLBINB_03028 2.7e-129 ykjA S Protein of unknown function (DUF421)
CDOLBINB_03029 2e-97 ykkA S Protein of unknown function (DUF664)
CDOLBINB_03030 2.5e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CDOLBINB_03031 3.5e-55 ykkC P Multidrug resistance protein
CDOLBINB_03032 7e-50 ykkD P Multidrug resistance protein
CDOLBINB_03033 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
CDOLBINB_03034 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDOLBINB_03035 6.9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDOLBINB_03036 1.3e-70 ohrA O Organic hydroperoxide resistance protein
CDOLBINB_03037 4.4e-74 ohrR K COG1846 Transcriptional regulators
CDOLBINB_03038 1.9e-71 ohrB O Organic hydroperoxide resistance protein
CDOLBINB_03039 8.1e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
CDOLBINB_03040 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CDOLBINB_03041 1.7e-176 isp O Belongs to the peptidase S8 family
CDOLBINB_03042 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CDOLBINB_03043 4e-136 ykoC P Cobalt transport protein
CDOLBINB_03044 3e-306 P ABC transporter, ATP-binding protein
CDOLBINB_03045 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
CDOLBINB_03046 2.5e-109 ykoF S YKOF-related Family
CDOLBINB_03047 9.6e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CDOLBINB_03048 1.6e-244 ykoH 2.7.13.3 T Histidine kinase
CDOLBINB_03049 3.3e-113 ykoI S Peptidase propeptide and YPEB domain
CDOLBINB_03050 1.1e-84 ykoJ S Peptidase propeptide and YPEB domain
CDOLBINB_03053 2.2e-222 mgtE P Acts as a magnesium transporter
CDOLBINB_03054 1.4e-53 tnrA K transcriptional
CDOLBINB_03055 5.9e-18
CDOLBINB_03056 6.9e-26 ykoL
CDOLBINB_03057 1.3e-81 mhqR K transcriptional
CDOLBINB_03058 1.8e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
CDOLBINB_03059 2.7e-97 ykoP G polysaccharide deacetylase
CDOLBINB_03060 3.9e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
CDOLBINB_03061 0.0 ykoS
CDOLBINB_03062 2.4e-184 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CDOLBINB_03063 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
CDOLBINB_03064 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CDOLBINB_03065 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
CDOLBINB_03066 2.7e-109 ykoX S membrane-associated protein
CDOLBINB_03067 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
CDOLBINB_03068 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDOLBINB_03069 1.8e-111 rsgI S Anti-sigma factor N-terminus
CDOLBINB_03070 1.9e-26 sspD S small acid-soluble spore protein
CDOLBINB_03071 3.3e-124 ykrK S Domain of unknown function (DUF1836)
CDOLBINB_03072 3.5e-155 htpX O Belongs to the peptidase M48B family
CDOLBINB_03073 3.1e-232 ktrB P COG0168 Trk-type K transport systems, membrane components
CDOLBINB_03074 1.2e-10 ydfR S Protein of unknown function (DUF421)
CDOLBINB_03075 4.1e-18 ykzE
CDOLBINB_03076 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
CDOLBINB_03077 0.0 kinE 2.7.13.3 T Histidine kinase
CDOLBINB_03078 1.3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDOLBINB_03080 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CDOLBINB_03081 1.3e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CDOLBINB_03082 1.3e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CDOLBINB_03083 8e-232 mtnE 2.6.1.83 E Aminotransferase
CDOLBINB_03084 1.3e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
CDOLBINB_03085 1.9e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CDOLBINB_03086 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
CDOLBINB_03087 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CDOLBINB_03088 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
CDOLBINB_03089 6.4e-09 S Spo0E like sporulation regulatory protein
CDOLBINB_03090 1.4e-64 eag
CDOLBINB_03091 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
CDOLBINB_03092 1.3e-75 ykvE K transcriptional
CDOLBINB_03093 2.5e-125 motB N Flagellar motor protein
CDOLBINB_03094 1e-137 motA N flagellar motor
CDOLBINB_03095 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CDOLBINB_03096 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
CDOLBINB_03097 2.3e-63 yngL S Protein of unknown function (DUF1360)
CDOLBINB_03098 4.2e-302 yngK T Glycosyl hydrolase-like 10
CDOLBINB_03099 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
CDOLBINB_03100 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CDOLBINB_03101 1.8e-248 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
CDOLBINB_03102 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
CDOLBINB_03103 2.6e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
CDOLBINB_03104 5.4e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
CDOLBINB_03105 2.7e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CDOLBINB_03106 3.6e-232 nrnB S phosphohydrolase (DHH superfamily)
CDOLBINB_03107 3.6e-103 yngC S membrane-associated protein
CDOLBINB_03108 1.2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CDOLBINB_03109 3.8e-78 yngA S membrane
CDOLBINB_03110 3.6e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
CDOLBINB_03111 5.3e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
CDOLBINB_03113 1.3e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
CDOLBINB_03114 1.8e-251 agcS E Sodium alanine symporter
CDOLBINB_03115 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CDOLBINB_03116 4.2e-161 citR K Transcriptional regulator
CDOLBINB_03117 7.7e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
CDOLBINB_03118 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CDOLBINB_03119 3.4e-250 yhdG E amino acid
CDOLBINB_03120 2.8e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CDOLBINB_03121 9.7e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CDOLBINB_03122 2e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CDOLBINB_03123 8.1e-45 yhdK S Sigma-M inhibitor protein
CDOLBINB_03124 3.3e-200 yhdL S Sigma factor regulator N-terminal
CDOLBINB_03125 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
CDOLBINB_03126 1.5e-191 yhdN C Aldo keto reductase
CDOLBINB_03127 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CDOLBINB_03128 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CDOLBINB_03129 4.1e-74 cueR K transcriptional
CDOLBINB_03130 9.7e-222 yhdR 2.6.1.1 E Aminotransferase
CDOLBINB_03131 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
CDOLBINB_03132 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDOLBINB_03133 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDOLBINB_03134 3.4e-132 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CDOLBINB_03136 9.9e-184 yhdY M Mechanosensitive ion channel
CDOLBINB_03137 2.5e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
CDOLBINB_03138 4.3e-147 yheN G deacetylase
CDOLBINB_03139 2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
CDOLBINB_03140 9.5e-229 nhaC C Na H antiporter
CDOLBINB_03141 9.9e-84 nhaX T Belongs to the universal stress protein A family
CDOLBINB_03142 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
CDOLBINB_03143 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
CDOLBINB_03144 4.9e-108 yheG GM NAD(P)H-binding
CDOLBINB_03145 6.3e-28 sspB S spore protein
CDOLBINB_03146 1.3e-36 yheE S Family of unknown function (DUF5342)
CDOLBINB_03147 6.3e-265 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
CDOLBINB_03148 2.4e-214 yheC HJ YheC/D like ATP-grasp
CDOLBINB_03149 2.2e-202 yheB S Belongs to the UPF0754 family
CDOLBINB_03150 9.5e-48 yheA S Belongs to the UPF0342 family
CDOLBINB_03151 7.5e-205 yhaZ L DNA alkylation repair enzyme
CDOLBINB_03152 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
CDOLBINB_03153 1.8e-292 hemZ H coproporphyrinogen III oxidase
CDOLBINB_03154 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
CDOLBINB_03155 1.3e-87 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
CDOLBINB_03157 6.7e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
CDOLBINB_03158 2.4e-26 S YhzD-like protein
CDOLBINB_03159 1.9e-100
CDOLBINB_03160 3.6e-113
CDOLBINB_03161 3.4e-63 yybN S Protein of unknown function (DUF2712)
CDOLBINB_03162 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
CDOLBINB_03164 1.6e-68
CDOLBINB_03165 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
CDOLBINB_03166 1.4e-68 ydeP3 K Transcriptional regulator
CDOLBINB_03167 3.9e-84 cotF M Spore coat protein
CDOLBINB_03169 2.9e-160 yybS S membrane
CDOLBINB_03170 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CDOLBINB_03171 2.2e-73 rplI J binds to the 23S rRNA
CDOLBINB_03172 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDOLBINB_03173 7.1e-220 yeaN P COG2807 Cyanate permease
CDOLBINB_03174 1.9e-15 yycC K YycC-like protein
CDOLBINB_03176 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
CDOLBINB_03177 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CDOLBINB_03178 1.3e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CDOLBINB_03179 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDOLBINB_03184 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CDOLBINB_03185 0.0 vicK 2.7.13.3 T Histidine kinase
CDOLBINB_03186 3.4e-258 yycH S protein conserved in bacteria
CDOLBINB_03187 6.2e-154 yycI S protein conserved in bacteria
CDOLBINB_03188 5.7e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
CDOLBINB_03189 3.2e-220 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDOLBINB_03190 6.4e-257 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
CDOLBINB_03191 8.1e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
CDOLBINB_03192 1e-254 rocE E amino acid
CDOLBINB_03193 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
CDOLBINB_03195 2.1e-186 S aspartate phosphatase
CDOLBINB_03196 5.5e-83 yycN 2.3.1.128 K Acetyltransferase
CDOLBINB_03197 1.3e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CDOLBINB_03198 6.2e-213 yycP
CDOLBINB_03199 3.3e-31 yycQ S Protein of unknown function (DUF2651)
CDOLBINB_03201 1.1e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CDOLBINB_03202 1.3e-64
CDOLBINB_03203 1.1e-09 S YyzF-like protein
CDOLBINB_03204 4.4e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDOLBINB_03205 1.4e-270 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
CDOLBINB_03206 1.7e-187 yoxA 5.1.3.3 G Aldose 1-epimerase
CDOLBINB_03207 2.3e-246 yoeA V MATE efflux family protein
CDOLBINB_03208 1.1e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CDOLBINB_03209 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDOLBINB_03210 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
CDOLBINB_03211 4.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
CDOLBINB_03212 1.1e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CDOLBINB_03213 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
CDOLBINB_03214 4.2e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDOLBINB_03215 9.5e-28 yjzC S YjzC-like protein
CDOLBINB_03216 2.3e-16 yjzD S Protein of unknown function (DUF2929)
CDOLBINB_03217 2.4e-141 yjaU I carboxylic ester hydrolase activity
CDOLBINB_03218 5.8e-100 yjaV
CDOLBINB_03219 2.5e-183 med S Transcriptional activator protein med
CDOLBINB_03220 1.6e-25 comZ S ComZ
CDOLBINB_03221 1.1e-20 yjzB
CDOLBINB_03222 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDOLBINB_03223 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CDOLBINB_03224 9.5e-149 yjaZ O Zn-dependent protease
CDOLBINB_03225 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
CDOLBINB_03226 2.3e-111 ywbG M effector of murein hydrolase
CDOLBINB_03227 3.1e-38 ywbF EGP Major facilitator Superfamily
CDOLBINB_03228 3.1e-139 ywbF EGP Major facilitator Superfamily
CDOLBINB_03229 3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
CDOLBINB_03230 2e-219 ywbD 2.1.1.191 J Methyltransferase
CDOLBINB_03231 4.4e-67 ywbC 4.4.1.5 E glyoxalase
CDOLBINB_03232 9.2e-124 ywbB S Protein of unknown function (DUF2711)
CDOLBINB_03233 7.8e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CDOLBINB_03234 2.2e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
CDOLBINB_03235 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CDOLBINB_03236 1.2e-152 sacY K transcriptional antiterminator
CDOLBINB_03237 7e-169 gspA M General stress
CDOLBINB_03238 3.3e-124 ywaF S Integral membrane protein
CDOLBINB_03239 8.1e-88 ywaE K Transcriptional regulator
CDOLBINB_03240 2.6e-194 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDOLBINB_03241 3.5e-13 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDOLBINB_03242 2.6e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
CDOLBINB_03243 1.8e-92 K Helix-turn-helix XRE-family like proteins
CDOLBINB_03244 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
CDOLBINB_03245 1.7e-128 ynfM EGP Major facilitator Superfamily
CDOLBINB_03246 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
CDOLBINB_03247 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
CDOLBINB_03248 2.8e-290 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CDOLBINB_03249 8e-232 dltB M membrane protein involved in D-alanine export
CDOLBINB_03250 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CDOLBINB_03251 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CDOLBINB_03252 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
CDOLBINB_03253 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CDOLBINB_03254 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CDOLBINB_03255 7.3e-50 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
CDOLBINB_03256 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CDOLBINB_03257 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
CDOLBINB_03258 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
CDOLBINB_03259 1.1e-19 yxzF
CDOLBINB_03260 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
CDOLBINB_03261 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
CDOLBINB_03262 1.4e-212 yxlH EGP Major facilitator Superfamily
CDOLBINB_03263 2.6e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CDOLBINB_03264 9.1e-164 yxlF V ABC transporter, ATP-binding protein
CDOLBINB_03265 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
CDOLBINB_03266 1.4e-30
CDOLBINB_03267 3.9e-48 yxlC S Family of unknown function (DUF5345)
CDOLBINB_03268 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
CDOLBINB_03269 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
CDOLBINB_03270 5.3e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDOLBINB_03271 0.0 cydD V ATP-binding protein
CDOLBINB_03272 7.1e-311 cydD V ATP-binding
CDOLBINB_03273 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
CDOLBINB_03274 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
CDOLBINB_03275 1.5e-229 cimH C COG3493 Na citrate symporter
CDOLBINB_03276 0.0 3.4.24.84 O Peptidase family M48
CDOLBINB_03278 1.6e-154 yxkH G Polysaccharide deacetylase
CDOLBINB_03279 5.9e-205 msmK P Belongs to the ABC transporter superfamily
CDOLBINB_03280 9.4e-161 lrp QT PucR C-terminal helix-turn-helix domain
CDOLBINB_03281 9.7e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CDOLBINB_03282 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDOLBINB_03283 2.7e-42 ylaB
CDOLBINB_03284 3.3e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
CDOLBINB_03285 1.2e-11 sigC S Putative zinc-finger
CDOLBINB_03286 2.6e-37 ylaE
CDOLBINB_03287 8.2e-22 S Family of unknown function (DUF5325)
CDOLBINB_03288 0.0 typA T GTP-binding protein TypA
CDOLBINB_03289 4.2e-47 ylaH S YlaH-like protein
CDOLBINB_03290 5.6e-32 ylaI S protein conserved in bacteria
CDOLBINB_03291 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CDOLBINB_03292 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
CDOLBINB_03293 3.6e-82 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDOLBINB_03294 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
CDOLBINB_03295 8.7e-44 ylaN S Belongs to the UPF0358 family
CDOLBINB_03296 2.5e-212 ftsW D Belongs to the SEDS family
CDOLBINB_03297 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CDOLBINB_03302 2e-08
CDOLBINB_03309 1.3e-09
CDOLBINB_03310 7.8e-08
CDOLBINB_03319 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDOLBINB_03320 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDOLBINB_03321 2.2e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
CDOLBINB_03322 4.6e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
CDOLBINB_03323 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CDOLBINB_03324 1.9e-75 tspO T membrane
CDOLBINB_03325 4.4e-205 cotI S Spore coat protein
CDOLBINB_03326 2.2e-215 cotSA M Glycosyl transferases group 1
CDOLBINB_03327 9.7e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
CDOLBINB_03329 3.7e-232 ytcC M Glycosyltransferase Family 4
CDOLBINB_03330 3.7e-179 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
CDOLBINB_03331 2.1e-241 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDOLBINB_03332 6.9e-150 galU 2.7.7.9 M Nucleotidyl transferase
CDOLBINB_03333 2.6e-132 dksA T COG1734 DnaK suppressor protein
CDOLBINB_03334 3.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
CDOLBINB_03335 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CDOLBINB_03336 6.1e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
CDOLBINB_03337 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CDOLBINB_03338 8.8e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CDOLBINB_03339 3.5e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
CDOLBINB_03340 1.7e-168 troA P Belongs to the bacterial solute-binding protein 9 family
CDOLBINB_03341 3.6e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CDOLBINB_03342 7.4e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CDOLBINB_03343 4.8e-149 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
CDOLBINB_03344 1.1e-24 S Domain of Unknown Function (DUF1540)
CDOLBINB_03345 4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
CDOLBINB_03346 1.8e-248 cydA 1.10.3.14 C oxidase, subunit
CDOLBINB_03347 3.6e-41 rpmE2 J Ribosomal protein L31
CDOLBINB_03348 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
CDOLBINB_03349 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CDOLBINB_03350 1.1e-72 ytkA S YtkA-like
CDOLBINB_03352 2.1e-76 dps P Belongs to the Dps family
CDOLBINB_03353 7e-63 ytkC S Bacteriophage holin family
CDOLBINB_03354 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
CDOLBINB_03355 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CDOLBINB_03356 4.1e-144 ytlC P ABC transporter
CDOLBINB_03357 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
CDOLBINB_03358 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
CDOLBINB_03359 1.2e-38 ytmB S Protein of unknown function (DUF2584)
CDOLBINB_03360 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CDOLBINB_03361 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDOLBINB_03362 0.0 asnB 6.3.5.4 E Asparagine synthase
CDOLBINB_03363 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
CDOLBINB_03364 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDOLBINB_03365 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
CDOLBINB_03366 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
CDOLBINB_03367 2.2e-105 ytqB J Putative rRNA methylase
CDOLBINB_03368 8.1e-190 yhcC S Fe-S oxidoreductase
CDOLBINB_03369 6.7e-41 ytzC S Protein of unknown function (DUF2524)
CDOLBINB_03371 5.1e-66 ytrA K GntR family transcriptional regulator
CDOLBINB_03372 1.2e-160 ytrB P abc transporter atp-binding protein
CDOLBINB_03373 1.8e-160 P ABC-2 family transporter protein
CDOLBINB_03374 6.7e-152
CDOLBINB_03375 3.1e-127 ytrE V ABC transporter, ATP-binding protein
CDOLBINB_03376 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
CDOLBINB_03377 4.9e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CDOLBINB_03378 1.6e-177 T PhoQ Sensor
CDOLBINB_03379 1.6e-137 bceA V ABC transporter, ATP-binding protein
CDOLBINB_03380 0.0 bceB V ABC transporter (permease)
CDOLBINB_03381 1.6e-41 yttA 2.7.13.3 S Pfam Transposase IS66
CDOLBINB_03382 1.3e-210 yttB EGP Major facilitator Superfamily
CDOLBINB_03383 1.1e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
CDOLBINB_03384 7.7e-55 ytvB S Protein of unknown function (DUF4257)
CDOLBINB_03385 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CDOLBINB_03386 2.1e-51 ytwF P Sulfurtransferase
CDOLBINB_03387 1.3e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
CDOLBINB_03388 4.4e-144 amyC P ABC transporter (permease)
CDOLBINB_03389 6.2e-168 amyD P ABC transporter
CDOLBINB_03390 4.4e-244 msmE G Bacterial extracellular solute-binding protein
CDOLBINB_03391 7.3e-189 msmR K Transcriptional regulator
CDOLBINB_03392 4.8e-229 xkdO L Transglycosylase SLT domain
CDOLBINB_03393 2.7e-118 xkdP S Lysin motif
CDOLBINB_03394 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
CDOLBINB_03395 2.3e-38 xkdR S Protein of unknown function (DUF2577)
CDOLBINB_03396 9e-69 xkdS S Protein of unknown function (DUF2634)
CDOLBINB_03397 7.4e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
CDOLBINB_03398 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
CDOLBINB_03399 2.5e-40
CDOLBINB_03400 1e-177
CDOLBINB_03401 3.1e-45 xkdW S XkdW protein
CDOLBINB_03402 5.5e-22 xkdX
CDOLBINB_03403 3.7e-151 xepA
CDOLBINB_03404 1.1e-38 xhlA S Haemolysin XhlA
CDOLBINB_03405 9.3e-40 xhlB S SPP1 phage holin
CDOLBINB_03406 1.2e-160 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CDOLBINB_03407 6.7e-23 spoIISB S Stage II sporulation protein SB
CDOLBINB_03408 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
CDOLBINB_03409 9.9e-175 pit P phosphate transporter
CDOLBINB_03410 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
CDOLBINB_03411 1.2e-239 steT E amino acid
CDOLBINB_03412 1.4e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
CDOLBINB_03413 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDOLBINB_03414 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CDOLBINB_03416 8.9e-211 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDOLBINB_03417 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
CDOLBINB_03418 5.1e-153 dppA E D-aminopeptidase
CDOLBINB_03419 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDOLBINB_03420 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDOLBINB_03421 7.3e-186 dppD P Belongs to the ABC transporter superfamily
CDOLBINB_03422 0.0 dppE E ABC transporter substrate-binding protein
CDOLBINB_03424 2.4e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
CDOLBINB_03425 9.1e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
CDOLBINB_03426 4e-167 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CDOLBINB_03427 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
CDOLBINB_03428 2.4e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
CDOLBINB_03429 3.8e-151 ykgA E Amidinotransferase
CDOLBINB_03430 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
CDOLBINB_03431 3.7e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
CDOLBINB_03432 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
CDOLBINB_03433 1.9e-278 yhjG CH FAD binding domain
CDOLBINB_03434 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
CDOLBINB_03435 2.6e-214 glcP G Major Facilitator Superfamily
CDOLBINB_03436 7.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
CDOLBINB_03437 2.4e-158 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
CDOLBINB_03438 5.9e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
CDOLBINB_03439 3.8e-187 yhjM 5.1.1.1 K Transcriptional regulator
CDOLBINB_03440 6e-200 abrB S membrane
CDOLBINB_03441 9.3e-212 EGP Transmembrane secretion effector
CDOLBINB_03442 0.0 S Sugar transport-related sRNA regulator N-term
CDOLBINB_03443 2e-36 yhjQ C COG1145 Ferredoxin
CDOLBINB_03444 6.4e-78 yhjR S Rubrerythrin
CDOLBINB_03445 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
CDOLBINB_03446 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CDOLBINB_03447 4.5e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CDOLBINB_03448 0.0 sbcC L COG0419 ATPase involved in DNA repair
CDOLBINB_03449 1.1e-49 yisB V COG1403 Restriction endonuclease
CDOLBINB_03450 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
CDOLBINB_03451 5.7e-65 gerPE S Spore germination protein GerPE
CDOLBINB_03452 1.1e-23 gerPD S Spore germination protein
CDOLBINB_03453 5.3e-54 gerPC S Spore germination protein
CDOLBINB_03454 1.6e-30 gerPB S cell differentiation
CDOLBINB_03455 1.9e-33 gerPA S Spore germination protein
CDOLBINB_03456 1.5e-22 yisI S Spo0E like sporulation regulatory protein
CDOLBINB_03457 9.1e-175 cotH M Spore Coat
CDOLBINB_03458 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
CDOLBINB_03459 3e-57 yisL S UPF0344 protein
CDOLBINB_03460 0.0 wprA O Belongs to the peptidase S8 family
CDOLBINB_03461 1.5e-100 yisN S Protein of unknown function (DUF2777)
CDOLBINB_03462 0.0 asnO 6.3.5.4 E Asparagine synthase
CDOLBINB_03463 1.8e-87 yizA S Damage-inducible protein DinB
CDOLBINB_03464 2e-146 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
CDOLBINB_03465 1.5e-242 yisQ V Mate efflux family protein
CDOLBINB_03466 1.2e-160 yisR K Transcriptional regulator
CDOLBINB_03467 6.9e-184 purR K helix_turn _helix lactose operon repressor
CDOLBINB_03468 7e-192 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
CDOLBINB_03469 1.8e-92 yisT S DinB family
CDOLBINB_03470 2.3e-105 argO S Lysine exporter protein LysE YggA
CDOLBINB_03471 4.8e-279 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CDOLBINB_03472 8.9e-36 mcbG S Pentapeptide repeats (9 copies)
CDOLBINB_03473 1.2e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CDOLBINB_03474 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
CDOLBINB_03475 1.9e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
CDOLBINB_03476 1.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
CDOLBINB_03477 3.1e-119 comB 3.1.3.71 H Belongs to the ComB family
CDOLBINB_03478 1.6e-140 yitD 4.4.1.19 S synthase
CDOLBINB_03479 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDOLBINB_03480 1.7e-220 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
CDOLBINB_03481 2.8e-227 yitG EGP Major facilitator Superfamily
CDOLBINB_03482 2.1e-154 yitH K Acetyltransferase (GNAT) domain
CDOLBINB_03483 3.2e-72 yjcF S Acetyltransferase (GNAT) domain
CDOLBINB_03484 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
CDOLBINB_03485 5.6e-54 yajQ S Belongs to the UPF0234 family
CDOLBINB_03486 6.9e-161 cvfB S protein conserved in bacteria
CDOLBINB_03487 8.5e-94
CDOLBINB_03488 4.7e-171
CDOLBINB_03489 1.5e-97 S Sporulation delaying protein SdpA
CDOLBINB_03490 1.5e-58 K Transcriptional regulator PadR-like family
CDOLBINB_03491 1.6e-92
CDOLBINB_03492 1.4e-44 yitR S Domain of unknown function (DUF3784)
CDOLBINB_03493 1.3e-309 nprB 3.4.24.28 E Peptidase M4
CDOLBINB_03494 1.4e-158 yitS S protein conserved in bacteria
CDOLBINB_03495 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
CDOLBINB_03496 5e-73 ipi S Intracellular proteinase inhibitor
CDOLBINB_03497 1.2e-17 S Protein of unknown function (DUF3813)
CDOLBINB_03498 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
CDOLBINB_03499 5e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
CDOLBINB_03500 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
CDOLBINB_03501 1.5e-22 pilT S Proteolipid membrane potential modulator
CDOLBINB_03502 3.4e-269 yitY C D-arabinono-1,4-lactone oxidase
CDOLBINB_03503 1.7e-88 norB G Major Facilitator Superfamily
CDOLBINB_03504 1.8e-78 carD K Transcription factor
CDOLBINB_03505 1.3e-138 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CDOLBINB_03506 1.9e-161 rhaS5 K AraC-like ligand binding domain
CDOLBINB_03507 7.5e-172 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CDOLBINB_03508 1.2e-163 ydeE K AraC family transcriptional regulator
CDOLBINB_03509 8.7e-262 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CDOLBINB_03510 9.9e-220 ydeG EGP Major facilitator superfamily
CDOLBINB_03511 6.1e-45 ydeH
CDOLBINB_03512 1.6e-103 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
CDOLBINB_03513 8.1e-101
CDOLBINB_03514 5.9e-152 ydeK EG -transporter
CDOLBINB_03515 4.9e-273 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CDOLBINB_03516 2.1e-73 maoC I N-terminal half of MaoC dehydratase
CDOLBINB_03517 3.2e-104 ydeN S Serine hydrolase
CDOLBINB_03518 9.8e-55 K HxlR-like helix-turn-helix
CDOLBINB_03519 1.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
CDOLBINB_03520 1.2e-184 ydeR EGP Major facilitator Superfamily
CDOLBINB_03521 9.3e-101 ydeS K Transcriptional regulator
CDOLBINB_03523 6.3e-22 arsR K transcriptional
CDOLBINB_03524 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CDOLBINB_03525 9.2e-144 ydfB J GNAT acetyltransferase
CDOLBINB_03526 8.3e-149 lytR K Transcriptional regulator
CDOLBINB_03527 4.5e-122 nodB1 G deacetylase
CDOLBINB_03528 9.5e-158
CDOLBINB_03529 1.7e-212 T GHKL domain
CDOLBINB_03530 1.5e-122 T Transcriptional regulatory protein, C terminal
CDOLBINB_03531 3e-146 ydfC EG EamA-like transporter family
CDOLBINB_03532 2.7e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CDOLBINB_03533 8.5e-116 ydfE S Flavin reductase like domain
CDOLBINB_03534 1.3e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
CDOLBINB_03535 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDOLBINB_03536 2.6e-174 ydfH 2.7.13.3 T Histidine kinase
CDOLBINB_03537 3.2e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CDOLBINB_03538 0.0 ydfJ S drug exporters of the RND superfamily
CDOLBINB_03539 8.5e-117 S Protein of unknown function (DUF554)
CDOLBINB_03540 7.3e-144 K Bacterial transcription activator, effector binding domain
CDOLBINB_03541 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDOLBINB_03542 2.2e-108 ydfN C nitroreductase
CDOLBINB_03543 2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
CDOLBINB_03544 1.2e-62 mhqP S DoxX
CDOLBINB_03545 1.2e-55 traF CO Thioredoxin
CDOLBINB_03546 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
CDOLBINB_03547 4.4e-30
CDOLBINB_03549 5.1e-97 ydfR S Protein of unknown function (DUF421)
CDOLBINB_03550 1.5e-121 ydfS S Protein of unknown function (DUF421)
CDOLBINB_03551 1.7e-67 cotP O Belongs to the small heat shock protein (HSP20) family
CDOLBINB_03552 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
CDOLBINB_03553 2.5e-32 ydgB S Spore germination protein gerPA/gerPF
CDOLBINB_03554 4.5e-98 K Bacterial regulatory proteins, tetR family
CDOLBINB_03555 2.1e-52 S DoxX-like family
CDOLBINB_03556 7.2e-83 yycN 2.3.1.128 K Acetyltransferase
CDOLBINB_03557 2.5e-300 expZ S ABC transporter
CDOLBINB_03558 7.5e-250 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
CDOLBINB_03559 2.5e-89 dinB S DinB family
CDOLBINB_03560 2.7e-79 K helix_turn_helix multiple antibiotic resistance protein
CDOLBINB_03561 0.0 ydgH S drug exporters of the RND superfamily
CDOLBINB_03562 1e-113 drgA C nitroreductase
CDOLBINB_03563 2.4e-69 ydgJ K Winged helix DNA-binding domain
CDOLBINB_03564 6.3e-208 tcaB EGP Major facilitator Superfamily
CDOLBINB_03565 1.6e-121 ydhB S membrane transporter protein
CDOLBINB_03566 3.2e-121 ydhC K FCD
CDOLBINB_03567 1.6e-243 ydhD M Glycosyl hydrolase
CDOLBINB_03568 2e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CDOLBINB_03569 5.1e-125
CDOLBINB_03570 2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
CDOLBINB_03571 1.6e-66 frataxin S Domain of unknown function (DU1801)
CDOLBINB_03574 6.8e-81 K Acetyltransferase (GNAT) domain
CDOLBINB_03575 4.9e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
CDOLBINB_03576 2.3e-96 ydhK M Protein of unknown function (DUF1541)
CDOLBINB_03577 4.6e-200 pbuE EGP Major facilitator Superfamily
CDOLBINB_03578 7.8e-08
CDOLBINB_03580 2.5e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CDOLBINB_03581 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
CDOLBINB_03582 6.5e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
CDOLBINB_03583 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CDOLBINB_03584 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDOLBINB_03585 0.0 ydiF S ABC transporter
CDOLBINB_03586 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CDOLBINB_03587 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CDOLBINB_03588 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CDOLBINB_03589 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDOLBINB_03590 2.9e-27 ydiK S Domain of unknown function (DUF4305)
CDOLBINB_03591 2.3e-128 ydiL S CAAX protease self-immunity
CDOLBINB_03592 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDOLBINB_03593 8.3e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CDOLBINB_03594 1.2e-11 S Helix-turn-helix of insertion element transposase
CDOLBINB_03598 1.8e-12 K PFAM Uncharacterised protein family UPF0150
CDOLBINB_03599 4.1e-08 N HicA toxin of bacterial toxin-antitoxin,
CDOLBINB_03600 1.2e-165 S Tetratricopeptide repeat
CDOLBINB_03602 3.1e-42 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDOLBINB_03603 8.1e-149 ypuA S Secreted protein
CDOLBINB_03604 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CDOLBINB_03605 1.4e-273 spoVAF EG Stage V sporulation protein AF
CDOLBINB_03606 1.4e-110 spoVAEA S stage V sporulation protein
CDOLBINB_03607 2.2e-57 spoVAEB S stage V sporulation protein
CDOLBINB_03608 9e-192 spoVAD I Stage V sporulation protein AD
CDOLBINB_03609 2.3e-78 spoVAC S stage V sporulation protein AC
CDOLBINB_03610 1e-67 spoVAB S Stage V sporulation protein AB
CDOLBINB_03611 9.6e-112 spoVAA S Stage V sporulation protein AA
CDOLBINB_03612 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDOLBINB_03613 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
CDOLBINB_03614 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
CDOLBINB_03615 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
CDOLBINB_03616 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CDOLBINB_03617 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
CDOLBINB_03618 5.3e-164 xerD L recombinase XerD
CDOLBINB_03619 3.7e-37 S Protein of unknown function (DUF4227)
CDOLBINB_03620 2.4e-80 fur P Belongs to the Fur family
CDOLBINB_03621 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
CDOLBINB_03622 6.7e-28 yqkK
CDOLBINB_03623 1.8e-195 S Ion transport 2 domain protein
CDOLBINB_03624 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
CDOLBINB_03625 3.4e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
CDOLBINB_03626 2.8e-177 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDOLBINB_03627 9.6e-113 pspA KT Phage shock protein A
CDOLBINB_03629 7.1e-150 rlmA 2.1.1.187 Q Methyltransferase domain
CDOLBINB_03630 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
CDOLBINB_03631 1.2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDOLBINB_03632 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CDOLBINB_03633 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
CDOLBINB_03634 3.1e-217 yxjG 2.1.1.14 E Methionine synthase
CDOLBINB_03635 9.7e-219 yxjG 2.1.1.14 E Methionine synthase
CDOLBINB_03636 3.2e-86 yxjI S LURP-one-related
CDOLBINB_03639 4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CDOLBINB_03640 3.9e-111 K helix_turn_helix, Lux Regulon
CDOLBINB_03641 4.7e-179 yxjM T Signal transduction histidine kinase
CDOLBINB_03642 5.9e-77 S Protein of unknown function (DUF1453)
CDOLBINB_03643 5.1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CDOLBINB_03644 1.3e-74 yxkC S Domain of unknown function (DUF4352)
CDOLBINB_03645 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
CDOLBINB_03646 5e-147 yjbA S Belongs to the UPF0736 family
CDOLBINB_03647 3.6e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDOLBINB_03648 2.2e-168 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDOLBINB_03649 2.8e-275 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
CDOLBINB_03650 2.7e-185 appF E Belongs to the ABC transporter superfamily
CDOLBINB_03651 1.8e-184 appD P Belongs to the ABC transporter superfamily
CDOLBINB_03652 1.6e-180 yaaC S YaaC-like Protein
CDOLBINB_03653 1.2e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CDOLBINB_03654 2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CDOLBINB_03655 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CDOLBINB_03656 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CDOLBINB_03657 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDOLBINB_03658 1.3e-09
CDOLBINB_03659 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
CDOLBINB_03660 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
CDOLBINB_03661 3.1e-213 yaaH M Glycoside Hydrolase Family
CDOLBINB_03662 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
CDOLBINB_03663 1.3e-82 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CDOLBINB_03664 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDOLBINB_03665 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDOLBINB_03666 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDOLBINB_03667 7.9e-32 yaaL S Protein of unknown function (DUF2508)
CDOLBINB_03668 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
CDOLBINB_03669 5.2e-37 S Putative amidase domain
CDOLBINB_03671 2.4e-212 yjcL S Protein of unknown function (DUF819)
CDOLBINB_03672 4.5e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
CDOLBINB_03673 8.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CDOLBINB_03674 8.6e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CDOLBINB_03675 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
CDOLBINB_03676 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
CDOLBINB_03677 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CDOLBINB_03678 1.7e-38
CDOLBINB_03679 0.0 yjcD 3.6.4.12 L DNA helicase
CDOLBINB_03680 2.9e-38 spoVIF S Stage VI sporulation protein F
CDOLBINB_03683 5.6e-56 yjcA S Protein of unknown function (DUF1360)
CDOLBINB_03684 3e-55 cotV S Spore Coat Protein X and V domain
CDOLBINB_03685 9.9e-23 cotW
CDOLBINB_03686 4e-71 cotX S Spore Coat Protein X and V domain
CDOLBINB_03687 3.4e-96 cotY S Spore coat protein Z
CDOLBINB_03688 5.2e-83 cotZ S Spore coat protein
CDOLBINB_03689 2.5e-52 yjbX S Spore coat protein
CDOLBINB_03690 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
CDOLBINB_03691 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CDOLBINB_03692 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CDOLBINB_03693 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
CDOLBINB_03694 6.7e-30 thiS H thiamine diphosphate biosynthetic process
CDOLBINB_03695 3.6e-218 thiO 1.4.3.19 E Glycine oxidase
CDOLBINB_03696 3e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
CDOLBINB_03697 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDOLBINB_03698 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CDOLBINB_03699 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
CDOLBINB_03700 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CDOLBINB_03701 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDOLBINB_03702 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
CDOLBINB_03703 2.1e-61 yjbL S Belongs to the UPF0738 family
CDOLBINB_03704 4.1e-101 yjbK S protein conserved in bacteria
CDOLBINB_03705 1.5e-95 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CDOLBINB_03706 3.7e-72 yjbI S Bacterial-like globin
CDOLBINB_03707 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
CDOLBINB_03708 1.8e-20
CDOLBINB_03709 0.0 pepF E oligoendopeptidase F
CDOLBINB_03710 4e-220 yjbF S Competence protein
CDOLBINB_03711 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CDOLBINB_03712 6e-112 yjbE P Integral membrane protein TerC family
CDOLBINB_03713 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CDOLBINB_03714 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CDOLBINB_03715 4.4e-206 yjbB EGP Major Facilitator Superfamily
CDOLBINB_03716 1.2e-171 oppF E Belongs to the ABC transporter superfamily
CDOLBINB_03717 1.5e-197 oppD P Belongs to the ABC transporter superfamily
CDOLBINB_03718 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDOLBINB_03719 1e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDOLBINB_03720 0.0 oppA E ABC transporter substrate-binding protein
CDOLBINB_03721 5.6e-169 alsR K LysR substrate binding domain
CDOLBINB_03722 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CDOLBINB_03723 6.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
CDOLBINB_03724 2.8e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
CDOLBINB_03725 8e-48 ywsA S Protein of unknown function (DUF3892)
CDOLBINB_03726 8.7e-93 batE T Sh3 type 3 domain protein
CDOLBINB_03727 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
CDOLBINB_03728 2.1e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
CDOLBINB_03729 9.5e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
CDOLBINB_03730 6.9e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CDOLBINB_03731 2.1e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDOLBINB_03732 9.3e-178 rbsR K transcriptional
CDOLBINB_03733 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
CDOLBINB_03734 8.6e-70 pgsC S biosynthesis protein
CDOLBINB_03735 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
CDOLBINB_03736 3.6e-21 ywtC
CDOLBINB_03737 5.9e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CDOLBINB_03738 7.7e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
CDOLBINB_03739 2.4e-170 ywtF K Transcriptional regulator
CDOLBINB_03740 1.7e-246 ywtG EGP Major facilitator Superfamily
CDOLBINB_03741 9.3e-206 gerAC S Spore germination protein
CDOLBINB_03742 2.6e-192 gerBB E Spore germination protein
CDOLBINB_03743 3.7e-263 gerBA EG Spore germination protein
CDOLBINB_03744 3.1e-186 pmi 5.3.1.8 G mannose-6-phosphate isomerase
CDOLBINB_03745 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CDOLBINB_03746 2e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CDOLBINB_03747 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CDOLBINB_03748 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
CDOLBINB_03749 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
CDOLBINB_03750 1.3e-94 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CDOLBINB_03751 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CDOLBINB_03752 2.1e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
CDOLBINB_03753 1.9e-145 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CDOLBINB_03754 1.4e-75 yxaI S membrane protein domain
CDOLBINB_03755 6.2e-224 P Protein of unknown function (DUF418)
CDOLBINB_03756 4.6e-196 yxaG 1.13.11.24 S AraC-like ligand binding domain
CDOLBINB_03757 1.3e-99 yxaF K Transcriptional regulator
CDOLBINB_03758 3.3e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CDOLBINB_03759 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
CDOLBINB_03760 7.6e-49 S LrgA family
CDOLBINB_03761 2.6e-118 yxaC M effector of murein hydrolase
CDOLBINB_03762 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
CDOLBINB_03763 1.9e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CDOLBINB_03764 7.3e-127 gntR K transcriptional
CDOLBINB_03765 2.3e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
CDOLBINB_03766 1.4e-229 gntP EG COG2610 H gluconate symporter and related permeases
CDOLBINB_03767 3.2e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CDOLBINB_03768 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
CDOLBINB_03769 1.2e-285 ahpF O Alkyl hydroperoxide reductase
CDOLBINB_03770 5.6e-189 wgaE S Polysaccharide pyruvyl transferase
CDOLBINB_03771 1.6e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CDOLBINB_03772 1.4e-19 bglF G phosphotransferase system
CDOLBINB_03773 1.6e-123 yydK K Transcriptional regulator
CDOLBINB_03774 3.3e-11
CDOLBINB_03775 5.3e-108 S ABC-2 family transporter protein
CDOLBINB_03776 3.3e-130 S Domain of unknown function, YrpD
CDOLBINB_03779 7.9e-25 tatA U protein secretion
CDOLBINB_03780 1.8e-71
CDOLBINB_03781 7.5e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
CDOLBINB_03784 1.8e-284 gerAA EG Spore germination protein
CDOLBINB_03785 1.8e-193 gerAB U Spore germination
CDOLBINB_03786 7.4e-217 gerLC S Spore germination protein
CDOLBINB_03787 1.4e-150 yndG S DoxX-like family
CDOLBINB_03788 5.4e-115 yndH S Domain of unknown function (DUF4166)
CDOLBINB_03789 3.7e-288 yndJ S YndJ-like protein
CDOLBINB_03791 5.2e-136 yndL S Replication protein
CDOLBINB_03792 1.7e-73 yndM S Protein of unknown function (DUF2512)
CDOLBINB_03793 3.7e-78 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
CDOLBINB_03794 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDOLBINB_03795 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
CDOLBINB_03796 9.2e-113 yneB L resolvase
CDOLBINB_03797 1.3e-32 ynzC S UPF0291 protein
CDOLBINB_03798 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDOLBINB_03799 1.5e-93 rok K Repressor of ComK
CDOLBINB_03800 2.1e-145 yknT
CDOLBINB_03801 1.6e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CDOLBINB_03802 5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CDOLBINB_03803 1.5e-244 moeA 2.10.1.1 H molybdopterin
CDOLBINB_03804 3.2e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
CDOLBINB_03805 1.4e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
CDOLBINB_03806 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CDOLBINB_03807 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
CDOLBINB_03808 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
CDOLBINB_03809 4.7e-115 yknW S Yip1 domain
CDOLBINB_03810 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDOLBINB_03811 2.5e-124 macB V ABC transporter, ATP-binding protein
CDOLBINB_03812 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
CDOLBINB_03813 2.6e-135 fruR K Transcriptional regulator
CDOLBINB_03814 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
CDOLBINB_03815 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
CDOLBINB_03816 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CDOLBINB_03817 8.1e-39 ykoA
CDOLBINB_03818 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CDOLBINB_03819 3.1e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CDOLBINB_03820 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
CDOLBINB_03821 1.1e-12 S Uncharacterized protein YkpC
CDOLBINB_03822 7.7e-183 mreB D Rod-share determining protein MreBH
CDOLBINB_03823 1.5e-43 abrB K of stationary sporulation gene expression
CDOLBINB_03824 1e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
CDOLBINB_03825 2.3e-153 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
CDOLBINB_03826 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
CDOLBINB_03827 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDOLBINB_03828 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CDOLBINB_03829 8.2e-31 ykzG S Belongs to the UPF0356 family
CDOLBINB_03830 2.7e-146 ykrA S hydrolases of the HAD superfamily
CDOLBINB_03831 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CDOLBINB_03833 1.1e-107 recN L Putative cell-wall binding lipoprotein
CDOLBINB_03834 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CDOLBINB_03835 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CDOLBINB_03836 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CDOLBINB_03837 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CDOLBINB_03838 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
CDOLBINB_03839 1e-276 speA 4.1.1.19 E Arginine
CDOLBINB_03840 1.6e-42 yktA S Belongs to the UPF0223 family
CDOLBINB_03841 4.6e-117 yktB S Belongs to the UPF0637 family
CDOLBINB_03842 7.1e-26 ykzI
CDOLBINB_03843 1.7e-148 suhB 3.1.3.25 G Inositol monophosphatase
CDOLBINB_03844 1.7e-76 ykzC S Acetyltransferase (GNAT) family
CDOLBINB_03845 3.5e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CDOLBINB_03846 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDOLBINB_03847 3.4e-39 ypmP S Protein of unknown function (DUF2535)
CDOLBINB_03848 7.1e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
CDOLBINB_03849 3.7e-137 ypmR E GDSL-like Lipase/Acylhydrolase
CDOLBINB_03850 4.2e-98 ypmS S protein conserved in bacteria
CDOLBINB_03851 1.6e-28 ypmT S Uncharacterized ympT
CDOLBINB_03852 3.8e-222 mepA V MATE efflux family protein
CDOLBINB_03853 1.6e-70 ypoP K transcriptional
CDOLBINB_03854 2.5e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDOLBINB_03855 3.7e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
CDOLBINB_03856 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
CDOLBINB_03857 2.2e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
CDOLBINB_03858 2.6e-177 cgeB S Spore maturation protein
CDOLBINB_03859 8.2e-64 cgeA
CDOLBINB_03860 2.9e-37 cgeC
CDOLBINB_03861 5.5e-255 cgeD M maturation of the outermost layer of the spore
CDOLBINB_03862 4.6e-143 yiiD K acetyltransferase
CDOLBINB_03864 4.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDOLBINB_03865 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDOLBINB_03866 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CDOLBINB_03867 1.9e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
CDOLBINB_03868 1.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
CDOLBINB_03869 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
CDOLBINB_03870 2.9e-47 yokU S YokU-like protein, putative antitoxin
CDOLBINB_03871 1.4e-36 yozE S Belongs to the UPF0346 family
CDOLBINB_03872 6e-123 yodN
CDOLBINB_03874 2.8e-24 yozD S YozD-like protein
CDOLBINB_03875 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
CDOLBINB_03876 3.6e-54 yodL S YodL-like
CDOLBINB_03877 5.3e-09
CDOLBINB_03878 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
CDOLBINB_03879 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
CDOLBINB_03880 1.5e-23 yodI
CDOLBINB_03881 5.4e-127 yodH Q Methyltransferase
CDOLBINB_03882 1.5e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
CDOLBINB_03883 3.3e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDOLBINB_03884 6.2e-28 S Protein of unknown function (DUF3311)
CDOLBINB_03889 2e-08
CDOLBINB_03894 2.3e-26 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CDOLBINB_03895 3.8e-131 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CDOLBINB_03896 9.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
CDOLBINB_03897 1.2e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CDOLBINB_03898 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
CDOLBINB_03899 6.2e-208 yfmO EGP Major facilitator Superfamily
CDOLBINB_03900 1.4e-69 yfmP K transcriptional
CDOLBINB_03901 6.3e-73 yfmQ S Uncharacterised protein from bacillus cereus group
CDOLBINB_03902 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CDOLBINB_03903 3.2e-113 yfmS NT chemotaxis protein
CDOLBINB_03904 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CDOLBINB_03905 6.4e-241 yfnA E amino acid
CDOLBINB_03906 6.8e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CDOLBINB_03907 6.6e-205 fsr P COG0477 Permeases of the major facilitator superfamily
CDOLBINB_03908 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
CDOLBINB_03909 3.2e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
CDOLBINB_03910 1.8e-178 yfnF M Nucleotide-diphospho-sugar transferase
CDOLBINB_03911 1.9e-172 yfnG 4.2.1.45 M dehydratase
CDOLBINB_03912 1.1e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
CDOLBINB_03913 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CDOLBINB_03914 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
CDOLBINB_03915 3.7e-196 yetN S Protein of unknown function (DUF3900)
CDOLBINB_03916 2.4e-77 L Transposase and inactivated derivatives, TnpA family
CDOLBINB_03917 4.2e-28
CDOLBINB_03918 2.3e-40 L Phage integrase family
CDOLBINB_03919 3.2e-23 L Phage integrase family
CDOLBINB_03920 3.2e-47 L Phage integrase family
CDOLBINB_03921 3.9e-94 L Belongs to the 'phage' integrase family
CDOLBINB_03922 2.6e-97 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDOLBINB_03923 3.9e-116 adaA 3.2.2.21 K Transcriptional regulator
CDOLBINB_03924 2.7e-171 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CDOLBINB_03925 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CDOLBINB_03926 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDOLBINB_03927 1.5e-224 ybbR S protein conserved in bacteria
CDOLBINB_03928 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CDOLBINB_03929 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
CDOLBINB_03930 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
CDOLBINB_03936 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
CDOLBINB_03937 1.9e-86 ybbJ J acetyltransferase
CDOLBINB_03938 3.9e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CDOLBINB_03939 1.4e-150 ybbH K transcriptional
CDOLBINB_03940 2.2e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CDOLBINB_03941 4.3e-250 yfeW 3.4.16.4 V Belongs to the UPF0214 family
CDOLBINB_03942 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
CDOLBINB_03943 9.2e-239 ybbC 3.2.1.52 S protein conserved in bacteria
CDOLBINB_03944 6.6e-290 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
CDOLBINB_03945 3e-165 feuA P Iron-uptake system-binding protein
CDOLBINB_03946 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDOLBINB_03947 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDOLBINB_03948 1.2e-135 ybbA S Putative esterase
CDOLBINB_03949 1.7e-160 ybaS 1.1.1.58 S Na -dependent transporter
CDOLBINB_03951 6.7e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
CDOLBINB_03952 1.6e-59 isp O Subtilase family
CDOLBINB_03953 6.4e-19
CDOLBINB_03954 1.5e-233 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CDOLBINB_03955 4e-89 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CDOLBINB_03956 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDOLBINB_03957 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDOLBINB_03958 1.8e-37 yaaB S Domain of unknown function (DUF370)
CDOLBINB_03959 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDOLBINB_03960 2.4e-33 yaaA S S4 domain
CDOLBINB_03961 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CDOLBINB_03962 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDOLBINB_03963 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CDOLBINB_03964 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CDOLBINB_03965 2.5e-107 jag S single-stranded nucleic acid binding R3H
CDOLBINB_03966 9.2e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDOLBINB_03967 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CDOLBINB_03968 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
CDOLBINB_03969 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
CDOLBINB_03970 1.5e-74 S Bacterial PH domain
CDOLBINB_03971 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
CDOLBINB_03972 2.1e-149 spo0J K Belongs to the ParB family
CDOLBINB_03973 1.6e-111 yyaC S Sporulation protein YyaC
CDOLBINB_03974 8.1e-177 yyaD S Membrane
CDOLBINB_03975 2.3e-33 yyzM S protein conserved in bacteria
CDOLBINB_03976 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CDOLBINB_03977 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CDOLBINB_03978 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
CDOLBINB_03979 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CDOLBINB_03980 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDOLBINB_03981 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
CDOLBINB_03982 5.6e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
CDOLBINB_03983 2e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CDOLBINB_03984 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
CDOLBINB_03985 3.2e-245 EGP Major facilitator superfamily
CDOLBINB_03986 3.6e-168 yyaK S CAAX protease self-immunity
CDOLBINB_03987 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
CDOLBINB_03988 3.4e-24 yyaL O Highly conserved protein containing a thioredoxin domain
CDOLBINB_03989 2.8e-160 yyaM EG EamA-like transporter family
CDOLBINB_03990 5.1e-61 yyaN K MerR HTH family regulatory protein
CDOLBINB_03991 6.7e-22 yyaR K acetyltransferase
CDOLBINB_03992 3.5e-25 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
CDOLBINB_03993 1.1e-106 yyaP 1.5.1.3 H RibD C-terminal domain
CDOLBINB_03994 6.6e-65 yyaQ S YjbR
CDOLBINB_03995 7.6e-94 yyaR K Acetyltransferase (GNAT) domain
CDOLBINB_03996 6.5e-97 yyaS S Membrane
CDOLBINB_03997 7.6e-71 yjcF S Acetyltransferase (GNAT) domain
CDOLBINB_03998 5.6e-77 yybA 2.3.1.57 K transcriptional
CDOLBINB_03999 6.6e-127 S Metallo-beta-lactamase superfamily
CDOLBINB_04000 6.6e-76 yybC
CDOLBINB_04001 5.5e-77 yjcF S Acetyltransferase (GNAT) domain
CDOLBINB_04002 3.4e-163 yybE K Transcriptional regulator
CDOLBINB_04003 4.3e-217 ynfM EGP Major facilitator Superfamily
CDOLBINB_04004 2e-120 yybG S Pentapeptide repeat-containing protein
CDOLBINB_04005 2.9e-66 yybH S SnoaL-like domain
CDOLBINB_04006 6.5e-129
CDOLBINB_04007 6e-112 V ATPases associated with a variety of cellular activities
CDOLBINB_04008 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
CDOLBINB_04009 5.7e-161 ybfH EG EamA-like transporter family
CDOLBINB_04010 2.3e-145 msmR K AraC-like ligand binding domain
CDOLBINB_04011 4e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CDOLBINB_04012 1.4e-175 mpr 3.4.21.19 M Belongs to the peptidase S1B family
CDOLBINB_04014 1.8e-167 S Alpha/beta hydrolase family
CDOLBINB_04015 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDOLBINB_04016 2.7e-85 ybfM S SNARE associated Golgi protein
CDOLBINB_04017 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
CDOLBINB_04018 4.6e-45 ybfN
CDOLBINB_04019 2.3e-251 S Erythromycin esterase
CDOLBINB_04020 6.7e-167 ybfP K Transcriptional regulator
CDOLBINB_04022 6.7e-102 bcrC 3.6.1.27 I Bacitracin ABC transporter permease
CDOLBINB_04025 1.3e-118 S ABC-2 family transporter protein
CDOLBINB_04026 1.3e-171 yhcH V ABC transporter, ATP-binding protein
CDOLBINB_04027 0.0 3.6.3.27 V Peptidase C39 family
CDOLBINB_04028 0.0 lcnDR2 V Domain of unknown function (DUF4135)
CDOLBINB_04029 1.8e-78 ydhU P Catalase
CDOLBINB_04030 2.2e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
CDOLBINB_04031 8.2e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
CDOLBINB_04032 1.8e-83 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
CDOLBINB_04033 1.1e-132 ydhQ K UTRA
CDOLBINB_04034 3.4e-282 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CDOLBINB_04035 5.8e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CDOLBINB_04036 4.3e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
CDOLBINB_04037 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
CDOLBINB_04038 6.2e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CDOLBINB_04040 1.4e-12 S HNH nucleases
CDOLBINB_04041 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
CDOLBINB_04042 1.7e-108 prrC P ABC transporter
CDOLBINB_04043 2.8e-56
CDOLBINB_04044 0.0 K NB-ARC domain
CDOLBINB_04045 9.4e-200 gutB 1.1.1.14 E Dehydrogenase
CDOLBINB_04046 5.6e-253 gutA G MFS/sugar transport protein
CDOLBINB_04047 2e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
CDOLBINB_04048 1e-07 S Bacteriocin subtilosin A
CDOLBINB_04049 4.9e-270 C Fe-S oxidoreductases
CDOLBINB_04051 3.7e-131 cbiO V ABC transporter
CDOLBINB_04052 3.8e-235 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
CDOLBINB_04053 1.2e-216 2.7.1.26, 2.7.7.2 L Peptidase, M16
CDOLBINB_04054 1.7e-248 L Peptidase, M16
CDOLBINB_04056 8.1e-244 ywhL CO amine dehydrogenase activity
CDOLBINB_04057 2.7e-191 ywhK CO amine dehydrogenase activity
CDOLBINB_04058 4.4e-78 S aspartate phosphatase
CDOLBINB_04060 1.4e-17 ywhH S Aminoacyl-tRNA editing domain
CDOLBINB_04061 1.2e-168 speB 3.5.3.11 E Belongs to the arginase family
CDOLBINB_04062 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CDOLBINB_04063 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CDOLBINB_04064 5.2e-95 ywhD S YwhD family
CDOLBINB_04065 5.1e-119 ywhC S Peptidase family M50
CDOLBINB_04066 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
CDOLBINB_04067 9.5e-71 ywhA K Transcriptional regulator
CDOLBINB_04068 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDOLBINB_04070 4.4e-237 mmr U Major Facilitator Superfamily
CDOLBINB_04071 5.3e-78 yffB K Transcriptional regulator
CDOLBINB_04072 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
CDOLBINB_04073 1.9e-255 ywfO S COG1078 HD superfamily phosphohydrolases
CDOLBINB_04074 3.1e-36 ywzC S Belongs to the UPF0741 family
CDOLBINB_04075 1e-110 rsfA_1
CDOLBINB_04076 1.7e-157 ywfM EG EamA-like transporter family
CDOLBINB_04077 2.5e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
CDOLBINB_04078 1.1e-156 cysL K Transcriptional regulator
CDOLBINB_04079 2.8e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
CDOLBINB_04080 1.1e-146 ywfI C May function as heme-dependent peroxidase
CDOLBINB_04081 1.9e-136 IQ Enoyl-(Acyl carrier protein) reductase
CDOLBINB_04082 1.1e-231 ywfG 2.6.1.83 E Aminotransferase class I and II
CDOLBINB_04083 8.6e-210 bacE EGP Major facilitator Superfamily
CDOLBINB_04084 6.1e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
CDOLBINB_04085 5.6e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CDOLBINB_04086 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
CDOLBINB_04087 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
CDOLBINB_04088 4.3e-204 ywfA EGP Major facilitator Superfamily
CDOLBINB_04089 1.1e-31 C Domain of unknown function (DUF4145)
CDOLBINB_04090 6.4e-52 S response regulator aspartate phosphatase
CDOLBINB_04095 2e-08
CDOLBINB_04099 5.4e-32
CDOLBINB_04100 8.7e-30 cspL K Cold shock
CDOLBINB_04102 6.6e-164 S Thymidylate synthase
CDOLBINB_04106 6.9e-10
CDOLBINB_04107 6.6e-84 S Protein of unknown function, DUF600
CDOLBINB_04108 0.0 L nucleic acid phosphodiester bond hydrolysis
CDOLBINB_04110 2.2e-96 L endonuclease activity
CDOLBINB_04111 3.4e-167 3.4.24.40 CO amine dehydrogenase activity
CDOLBINB_04112 7.2e-52
CDOLBINB_04113 2.5e-211 S Tetratricopeptide repeat
CDOLBINB_04115 2.7e-126 yeeN K transcriptional regulatory protein
CDOLBINB_04117 1e-99 dhaR3 K Transcriptional regulator
CDOLBINB_04118 6.9e-80 yesE S SnoaL-like domain
CDOLBINB_04119 1.3e-151 yesF GM NAD(P)H-binding
CDOLBINB_04120 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
CDOLBINB_04121 1.3e-44 cotJB S CotJB protein
CDOLBINB_04122 5.2e-104 cotJC P Spore Coat
CDOLBINB_04123 2.3e-101 yesJ K Acetyltransferase (GNAT) family
CDOLBINB_04125 5.9e-101 yesL S Protein of unknown function, DUF624
CDOLBINB_04126 0.0 yesM 2.7.13.3 T Histidine kinase
CDOLBINB_04127 2.4e-198 yesN K helix_turn_helix, arabinose operon control protein
CDOLBINB_04128 2.8e-246 yesO G Bacterial extracellular solute-binding protein
CDOLBINB_04129 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
CDOLBINB_04130 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
CDOLBINB_04131 7.8e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
CDOLBINB_04132 0.0 yesS K Transcriptional regulator
CDOLBINB_04133 4.8e-128 E GDSL-like Lipase/Acylhydrolase
CDOLBINB_04134 2.4e-129 yesU S Domain of unknown function (DUF1961)
CDOLBINB_04135 1.5e-112 yesV S Protein of unknown function, DUF624
CDOLBINB_04136 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
CDOLBINB_04137 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)