ORF_ID e_value Gene_name EC_number CAZy COGs Description
COEPHNDF_00001 3.2e-222 V ABC-type multidrug transport system, ATPase and permease components
COEPHNDF_00002 1.7e-19 V ABC-type multidrug transport system, ATPase and permease components
COEPHNDF_00004 1.4e-33
COEPHNDF_00006 2.2e-131 K response regulator
COEPHNDF_00007 2e-306 vicK 2.7.13.3 T Histidine kinase
COEPHNDF_00008 6.7e-243 yycH S YycH protein
COEPHNDF_00009 2.7e-146 yycI S YycH protein
COEPHNDF_00010 3.3e-149 vicX 3.1.26.11 S domain protein
COEPHNDF_00011 1.4e-181 htrA 3.4.21.107 O serine protease
COEPHNDF_00012 4.3e-91 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COEPHNDF_00013 5.6e-38 K Helix-turn-helix XRE-family like proteins
COEPHNDF_00014 8.8e-25 K Helix-turn-helix XRE-family like proteins
COEPHNDF_00016 3.9e-82 V ABC transporter
COEPHNDF_00017 9.2e-40
COEPHNDF_00018 5.6e-30 higA K Helix-turn-helix XRE-family like proteins
COEPHNDF_00019 6.3e-173 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
COEPHNDF_00020 1.3e-90 P Cobalt transport protein
COEPHNDF_00021 1.4e-245 cbiO1 S ABC transporter, ATP-binding protein
COEPHNDF_00022 1.9e-172 K helix_turn_helix, arabinose operon control protein
COEPHNDF_00023 7e-37 L hmm pf00665
COEPHNDF_00024 2.3e-36 L hmm pf00665
COEPHNDF_00025 1.3e-60 L hmm pf00665
COEPHNDF_00026 3.5e-113 L Helix-turn-helix domain
COEPHNDF_00027 3.9e-162 htpX O Belongs to the peptidase M48B family
COEPHNDF_00028 2.3e-96 lemA S LemA family
COEPHNDF_00029 4.9e-191 ybiR P Citrate transporter
COEPHNDF_00030 7.7e-70 S Iron-sulphur cluster biosynthesis
COEPHNDF_00031 1e-60 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
COEPHNDF_00032 1.5e-236 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
COEPHNDF_00033 1.2e-17
COEPHNDF_00034 2.4e-121 yfbR S HD containing hydrolase-like enzyme
COEPHNDF_00035 6.3e-162 L HNH nucleases
COEPHNDF_00036 8.1e-137 glnQ E ABC transporter, ATP-binding protein
COEPHNDF_00037 4.1e-287 glnP P ABC transporter permease
COEPHNDF_00038 1.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
COEPHNDF_00039 1.8e-62 yeaO S Protein of unknown function, DUF488
COEPHNDF_00040 2.5e-120 terC P Integral membrane protein TerC family
COEPHNDF_00041 3.5e-91 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
COEPHNDF_00042 1.4e-130 cobB K SIR2 family
COEPHNDF_00043 3.5e-85
COEPHNDF_00044 1.7e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COEPHNDF_00045 6.8e-178 S Alpha/beta hydrolase of unknown function (DUF915)
COEPHNDF_00046 2.1e-145 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COEPHNDF_00047 2.4e-138 ypuA S Protein of unknown function (DUF1002)
COEPHNDF_00048 1.2e-159 epsV 2.7.8.12 S glycosyl transferase family 2
COEPHNDF_00049 5.6e-126 S Alpha/beta hydrolase family
COEPHNDF_00050 1.5e-115 GM NmrA-like family
COEPHNDF_00051 2.5e-55
COEPHNDF_00052 1.4e-181 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COEPHNDF_00053 8.7e-122 luxT K Bacterial regulatory proteins, tetR family
COEPHNDF_00054 1e-129
COEPHNDF_00055 7.8e-261 glnPH2 P ABC transporter permease
COEPHNDF_00056 1.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COEPHNDF_00057 3.2e-231 S Cysteine-rich secretory protein family
COEPHNDF_00058 2.4e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
COEPHNDF_00059 6.3e-94
COEPHNDF_00060 2.2e-199 yibE S overlaps another CDS with the same product name
COEPHNDF_00061 6.4e-129 yibF S overlaps another CDS with the same product name
COEPHNDF_00062 3.8e-156 I alpha/beta hydrolase fold
COEPHNDF_00063 4.9e-31
COEPHNDF_00064 0.0 G Belongs to the glycosyl hydrolase 31 family
COEPHNDF_00065 5.7e-80 ntd 2.4.2.6 F Nucleoside
COEPHNDF_00066 5.6e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
COEPHNDF_00067 3.1e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
COEPHNDF_00068 5.5e-86 uspA T universal stress protein
COEPHNDF_00070 6e-150 phnD P Phosphonate ABC transporter
COEPHNDF_00071 5.7e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
COEPHNDF_00072 1.6e-127 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
COEPHNDF_00073 4.6e-146 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
COEPHNDF_00074 7.8e-108 tag 3.2.2.20 L glycosylase
COEPHNDF_00075 1.1e-81
COEPHNDF_00076 1.1e-272 S Calcineurin-like phosphoesterase
COEPHNDF_00077 0.0 asnB 6.3.5.4 E Asparagine synthase
COEPHNDF_00078 1.4e-253 yxbA 6.3.1.12 S ATP-grasp enzyme
COEPHNDF_00081 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
COEPHNDF_00082 4.3e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COEPHNDF_00083 7.8e-100 S Iron-sulfur cluster assembly protein
COEPHNDF_00084 7.5e-230 XK27_04775 S PAS domain
COEPHNDF_00085 5.7e-225 yttB EGP Major facilitator Superfamily
COEPHNDF_00086 0.0 pepO 3.4.24.71 O Peptidase family M13
COEPHNDF_00087 0.0 kup P Transport of potassium into the cell
COEPHNDF_00088 3.8e-71
COEPHNDF_00090 1e-28
COEPHNDF_00091 1.3e-36 S Protein of unknown function (DUF2922)
COEPHNDF_00092 3.2e-165 S SLAP domain
COEPHNDF_00094 5.4e-12 K DNA-templated transcription, initiation
COEPHNDF_00095 7.1e-26 K DNA-templated transcription, initiation
COEPHNDF_00096 2.4e-97
COEPHNDF_00097 3.7e-224 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COEPHNDF_00098 1.3e-209 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
COEPHNDF_00099 0.0 yjbQ P TrkA C-terminal domain protein
COEPHNDF_00100 1.1e-24 gepA K Protein of unknown function (DUF4065)
COEPHNDF_00101 7.4e-93 gepA K Protein of unknown function (DUF4065)
COEPHNDF_00102 1.1e-178 S Oxidoreductase family, NAD-binding Rossmann fold
COEPHNDF_00103 3e-118
COEPHNDF_00104 1.1e-133
COEPHNDF_00105 1.9e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COEPHNDF_00106 7.4e-109 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
COEPHNDF_00107 5.3e-101 G Aldose 1-epimerase
COEPHNDF_00108 3.6e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COEPHNDF_00109 1.3e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COEPHNDF_00110 0.0 XK27_08315 M Sulfatase
COEPHNDF_00111 9e-267 S Fibronectin type III domain
COEPHNDF_00112 9.7e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COEPHNDF_00113 5.4e-21
COEPHNDF_00115 1.6e-257 pepC 3.4.22.40 E aminopeptidase
COEPHNDF_00116 2.1e-117 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
COEPHNDF_00117 2.2e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COEPHNDF_00118 8.8e-256 pepC 3.4.22.40 E aminopeptidase
COEPHNDF_00119 2.6e-68 hsp O Belongs to the small heat shock protein (HSP20) family
COEPHNDF_00120 1.8e-75 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COEPHNDF_00121 4.9e-114
COEPHNDF_00123 4.5e-114 E Belongs to the SOS response-associated peptidase family
COEPHNDF_00124 1.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
COEPHNDF_00125 5.5e-91 comEB 3.5.4.12 F MafB19-like deaminase
COEPHNDF_00126 4.6e-109 S TPM domain
COEPHNDF_00127 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
COEPHNDF_00128 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COEPHNDF_00129 1e-147 tatD L hydrolase, TatD family
COEPHNDF_00130 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
COEPHNDF_00131 2.1e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COEPHNDF_00132 5e-38 veg S Biofilm formation stimulator VEG
COEPHNDF_00133 2.2e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
COEPHNDF_00134 2.1e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COEPHNDF_00135 3.8e-45 msmR7 K helix_turn_helix, arabinose operon control protein
COEPHNDF_00136 2.8e-99 msmR7 K helix_turn_helix, arabinose operon control protein
COEPHNDF_00137 1.4e-130 scrB 3.2.1.26 GH32 G invertase
COEPHNDF_00138 3.3e-215 scrA 2.7.1.208, 2.7.1.211 G phosphotransferase system
COEPHNDF_00139 4.5e-90 scrA 2.7.1.208, 2.7.1.211 G phosphotransferase system
COEPHNDF_00140 8.6e-41 rafA 3.2.1.22 G alpha-galactosidase
COEPHNDF_00141 3.2e-173 rafA 3.2.1.22 G alpha-galactosidase
COEPHNDF_00142 9.7e-65 rafA 3.2.1.22 G alpha-galactosidase
COEPHNDF_00143 1.3e-187 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
COEPHNDF_00144 3.1e-134 manY G PTS system
COEPHNDF_00145 2.2e-173 manN G system, mannose fructose sorbose family IID component
COEPHNDF_00146 7.6e-64 manO S Domain of unknown function (DUF956)
COEPHNDF_00147 2.4e-104 K Transcriptional regulator
COEPHNDF_00148 1.2e-22 K Transcriptional regulator
COEPHNDF_00149 1.4e-82 maa S transferase hexapeptide repeat
COEPHNDF_00150 8.6e-238 cycA E Amino acid permease
COEPHNDF_00151 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
COEPHNDF_00152 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COEPHNDF_00153 8.8e-47
COEPHNDF_00154 1e-102 yagE E amino acid
COEPHNDF_00155 1e-72
COEPHNDF_00156 6.2e-90 UW LPXTG-motif cell wall anchor domain protein
COEPHNDF_00157 3.3e-80 S LPXTG cell wall anchor motif
COEPHNDF_00158 1.2e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COEPHNDF_00159 1.5e-132 4.1.1.44 S Carboxymuconolactone decarboxylase family
COEPHNDF_00160 6.4e-37
COEPHNDF_00161 7.7e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
COEPHNDF_00162 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
COEPHNDF_00163 2e-258 S TerB-C domain
COEPHNDF_00164 2.3e-251 P P-loop Domain of unknown function (DUF2791)
COEPHNDF_00165 0.0 lhr L DEAD DEAH box helicase
COEPHNDF_00166 5.1e-60
COEPHNDF_00167 2.9e-139 S Uncharacterized protein conserved in bacteria (DUF2263)
COEPHNDF_00168 1.3e-13 K Bacterial regulatory helix-turn-helix protein, lysR family
COEPHNDF_00169 3e-49 C FAD binding domain
COEPHNDF_00170 3.1e-26 C FAD binding domain
COEPHNDF_00171 1e-71 C FAD binding domain
COEPHNDF_00173 1.9e-127 XK27_08435 K UTRA
COEPHNDF_00174 3.1e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
COEPHNDF_00175 2.8e-53 rpiR1 K Helix-turn-helix domain, rpiR family
COEPHNDF_00176 4.1e-71 S Iron-sulphur cluster biosynthesis
COEPHNDF_00177 7.1e-32
COEPHNDF_00178 2.1e-67
COEPHNDF_00179 1.5e-95 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
COEPHNDF_00180 1.1e-25 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
COEPHNDF_00181 5.6e-13
COEPHNDF_00182 2.8e-51 M LysM domain protein
COEPHNDF_00183 6.3e-196 D nuclear chromosome segregation
COEPHNDF_00184 3.4e-111 G Phosphoglycerate mutase family
COEPHNDF_00185 8.5e-229 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
COEPHNDF_00186 3.2e-132 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
COEPHNDF_00187 7.2e-135 gmuR K UTRA
COEPHNDF_00188 9.7e-63 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COEPHNDF_00189 3.2e-242 amtB P ammonium transporter
COEPHNDF_00190 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COEPHNDF_00191 3.3e-95 L Transposase
COEPHNDF_00192 9.8e-21 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
COEPHNDF_00193 3.9e-96 E Amino acid permease
COEPHNDF_00194 3.2e-161 E Amino acid permease
COEPHNDF_00195 2.1e-255 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
COEPHNDF_00198 5.5e-29 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
COEPHNDF_00199 2.9e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COEPHNDF_00200 2.1e-64 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COEPHNDF_00201 4.3e-71 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
COEPHNDF_00202 5.9e-155 glcU U sugar transport
COEPHNDF_00203 3.6e-151 xerD L Phage integrase, N-terminal SAM-like domain
COEPHNDF_00204 5.1e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
COEPHNDF_00205 7.3e-194 pbpX1 V Beta-lactamase
COEPHNDF_00206 0.0 L Helicase C-terminal domain protein
COEPHNDF_00207 1.4e-262 E amino acid
COEPHNDF_00208 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
COEPHNDF_00209 4.1e-92 yniA G Phosphotransferase enzyme family
COEPHNDF_00210 8.9e-68 yniA G Phosphotransferase enzyme family
COEPHNDF_00211 3.4e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEPHNDF_00212 3.3e-56
COEPHNDF_00213 6.4e-46
COEPHNDF_00214 6.7e-269 nisT V ABC transporter
COEPHNDF_00215 7.9e-154 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
COEPHNDF_00216 0.0 tetP J elongation factor G
COEPHNDF_00217 1.4e-164 yvgN C Aldo keto reductase
COEPHNDF_00218 1.1e-211 S SLAP domain
COEPHNDF_00219 1.7e-15 S Bacteriocin helveticin-J
COEPHNDF_00220 9.2e-135 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
COEPHNDF_00221 1e-176 ABC-SBP S ABC transporter
COEPHNDF_00222 2.2e-125 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
COEPHNDF_00223 9.6e-138 XK27_08845 S ABC transporter, ATP-binding protein
COEPHNDF_00224 3.2e-51
COEPHNDF_00225 1.3e-11
COEPHNDF_00226 6.8e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
COEPHNDF_00227 7.1e-176 K AI-2E family transporter
COEPHNDF_00228 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
COEPHNDF_00229 2.1e-59 S Domain of unknown function (DUF4430)
COEPHNDF_00230 1.7e-85 S ECF transporter, substrate-specific component
COEPHNDF_00231 2.5e-98 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
COEPHNDF_00232 6.1e-148 S Putative ABC-transporter type IV
COEPHNDF_00233 3.2e-232 S LPXTG cell wall anchor motif
COEPHNDF_00234 2.5e-59 pipD E Dipeptidase
COEPHNDF_00235 2.3e-48 vsr L DNA mismatch endonuclease Vsr
COEPHNDF_00236 2e-147 2.1.1.37 H C-5 cytosine-specific DNA methylase
COEPHNDF_00237 3.2e-211 Z012_07420 3.1.21.5 V Z1 domain
COEPHNDF_00238 9e-106 L NgoFVII restriction endonuclease
COEPHNDF_00239 8.3e-105 K Bacterial regulatory proteins, tetR family
COEPHNDF_00240 2.3e-23 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COEPHNDF_00241 2.4e-140 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COEPHNDF_00245 5e-142 L COG3547 Transposase and inactivated derivatives
COEPHNDF_00256 1.5e-155 L COG2963 Transposase and inactivated derivatives
COEPHNDF_00257 3.2e-158 L An automated process has identified a potential problem with this gene model
COEPHNDF_00258 1.4e-68 L Transposase and inactivated derivatives, IS30 family
COEPHNDF_00259 4.4e-86 L Resolvase, N terminal domain
COEPHNDF_00260 7.3e-154 EGP Major facilitator Superfamily
COEPHNDF_00261 3.7e-42 EGP Major facilitator Superfamily
COEPHNDF_00262 4.6e-196 ampC V Beta-lactamase
COEPHNDF_00265 1.8e-248 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
COEPHNDF_00266 2.2e-113 tdk 2.7.1.21 F thymidine kinase
COEPHNDF_00267 6.9e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COEPHNDF_00268 3.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COEPHNDF_00269 1.9e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COEPHNDF_00270 2e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COEPHNDF_00271 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
COEPHNDF_00272 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COEPHNDF_00273 7.3e-49 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COEPHNDF_00274 6.8e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COEPHNDF_00275 2.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COEPHNDF_00276 2e-169 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COEPHNDF_00277 1.3e-233 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COEPHNDF_00278 2.2e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
COEPHNDF_00279 5.8e-30 ywzB S Protein of unknown function (DUF1146)
COEPHNDF_00280 1.9e-178 mbl D Cell shape determining protein MreB Mrl
COEPHNDF_00281 3.8e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
COEPHNDF_00282 8.6e-34 S Protein of unknown function (DUF2969)
COEPHNDF_00283 3.1e-215 rodA D Belongs to the SEDS family
COEPHNDF_00284 4e-78 usp6 T universal stress protein
COEPHNDF_00285 2.5e-35
COEPHNDF_00286 8e-241 rarA L recombination factor protein RarA
COEPHNDF_00287 2.7e-82 yueI S Protein of unknown function (DUF1694)
COEPHNDF_00288 1.8e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COEPHNDF_00289 3.2e-282 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
COEPHNDF_00290 7.1e-217 iscS2 2.8.1.7 E Aminotransferase class V
COEPHNDF_00291 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COEPHNDF_00292 8.7e-143 K Helix-turn-helix domain
COEPHNDF_00293 7.1e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COEPHNDF_00294 5.8e-26 K Helix-turn-helix XRE-family like proteins
COEPHNDF_00295 3.9e-66
COEPHNDF_00296 3.8e-20
COEPHNDF_00297 1.1e-89
COEPHNDF_00298 4.4e-132 K Helix-turn-helix XRE-family like proteins
COEPHNDF_00299 1.3e-307 S SLAP domain
COEPHNDF_00300 5.7e-82 S Protein of unknown function (DUF3232)
COEPHNDF_00302 1.7e-121
COEPHNDF_00303 2.7e-17 K Helix-turn-helix XRE-family like proteins
COEPHNDF_00304 3.1e-142 K Helix-turn-helix XRE-family like proteins
COEPHNDF_00305 2.2e-75 L Transposase and inactivated derivatives, IS30 family
COEPHNDF_00306 9.3e-77 L COG3547 Transposase and inactivated derivatives
COEPHNDF_00307 5.4e-59
COEPHNDF_00308 4.9e-116 L COG2963 Transposase and inactivated derivatives
COEPHNDF_00309 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COEPHNDF_00310 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COEPHNDF_00311 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COEPHNDF_00312 2.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
COEPHNDF_00314 1.6e-08
COEPHNDF_00315 1.8e-26
COEPHNDF_00317 1.3e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
COEPHNDF_00318 1e-195 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COEPHNDF_00319 5e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COEPHNDF_00320 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COEPHNDF_00321 4.5e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COEPHNDF_00322 2.2e-60 yabR J S1 RNA binding domain
COEPHNDF_00323 5.8e-59 divIC D Septum formation initiator
COEPHNDF_00324 1.8e-34 yabO J S4 domain protein
COEPHNDF_00325 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COEPHNDF_00326 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COEPHNDF_00327 7.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COEPHNDF_00328 2.4e-127 S (CBS) domain
COEPHNDF_00329 2.9e-92 K transcriptional regulator
COEPHNDF_00330 3.4e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COEPHNDF_00331 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COEPHNDF_00332 5.5e-246 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
COEPHNDF_00333 1e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COEPHNDF_00334 1.3e-38 rpmE2 J Ribosomal protein L31
COEPHNDF_00335 1.3e-156 S Sucrose-6F-phosphate phosphohydrolase
COEPHNDF_00336 7.3e-26 ybeC E amino acid
COEPHNDF_00337 2.1e-194 ybeC E amino acid
COEPHNDF_00338 2.5e-44 ybeC E amino acid
COEPHNDF_00339 1.2e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COEPHNDF_00340 2e-76 L Probable transposase
COEPHNDF_00341 4e-65 L Transposase
COEPHNDF_00342 0.0 S SH3-like domain
COEPHNDF_00343 7.5e-133 S haloacid dehalogenase-like hydrolase
COEPHNDF_00344 2.3e-270 ycaM E amino acid
COEPHNDF_00345 9e-160
COEPHNDF_00346 9e-77
COEPHNDF_00348 1.2e-188 cggR K Putative sugar-binding domain
COEPHNDF_00349 8.4e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COEPHNDF_00350 9.3e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
COEPHNDF_00351 1.2e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COEPHNDF_00352 5.3e-95
COEPHNDF_00353 2.4e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
COEPHNDF_00354 3.3e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COEPHNDF_00355 1.8e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
COEPHNDF_00356 6.4e-90 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
COEPHNDF_00357 1.4e-98 dnaQ 2.7.7.7 L DNA polymerase III
COEPHNDF_00358 4.1e-164 murB 1.3.1.98 M Cell wall formation
COEPHNDF_00359 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COEPHNDF_00360 5.1e-129 potB P ABC transporter permease
COEPHNDF_00361 1.7e-132 potC P ABC transporter permease
COEPHNDF_00362 5.6e-208 potD P ABC transporter
COEPHNDF_00363 4.2e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COEPHNDF_00364 2.4e-170 ybbR S YbbR-like protein
COEPHNDF_00365 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COEPHNDF_00366 2.6e-149 S hydrolase
COEPHNDF_00367 3.8e-148 S Sucrose-6F-phosphate phosphohydrolase
COEPHNDF_00368 1.8e-117
COEPHNDF_00369 9.9e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COEPHNDF_00370 7.8e-216 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
COEPHNDF_00371 4.9e-143 licT K CAT RNA binding domain
COEPHNDF_00372 0.0 bglP G phosphotransferase system
COEPHNDF_00373 1.9e-21 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COEPHNDF_00374 1.8e-239 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COEPHNDF_00375 1.1e-183 D Alpha beta
COEPHNDF_00376 5.8e-286 E Amino acid permease
COEPHNDF_00377 1.4e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
COEPHNDF_00378 5.1e-173 degV S DegV family
COEPHNDF_00379 3.3e-164 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
COEPHNDF_00380 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
COEPHNDF_00381 1.1e-67 rplI J Binds to the 23S rRNA
COEPHNDF_00382 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
COEPHNDF_00383 3.2e-31 S SLAP domain
COEPHNDF_00384 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COEPHNDF_00385 9e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COEPHNDF_00386 4.2e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
COEPHNDF_00387 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COEPHNDF_00388 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COEPHNDF_00389 9e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COEPHNDF_00390 1.7e-34 yaaA S S4 domain protein YaaA
COEPHNDF_00391 3.9e-196 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COEPHNDF_00392 4.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COEPHNDF_00393 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
COEPHNDF_00394 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COEPHNDF_00395 3e-143 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COEPHNDF_00396 6.2e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COEPHNDF_00397 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COEPHNDF_00398 1.1e-269 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COEPHNDF_00399 3.2e-281 clcA P chloride
COEPHNDF_00400 7.2e-211
COEPHNDF_00401 1.2e-18
COEPHNDF_00402 8.5e-81 EGP Sugar (and other) transporter
COEPHNDF_00403 2.2e-38 EGP Sugar (and other) transporter
COEPHNDF_00404 5.6e-17 EGP Sugar (and other) transporter
COEPHNDF_00405 0.0 copA 3.6.3.54 P P-type ATPase
COEPHNDF_00406 1.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
COEPHNDF_00407 1.2e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
COEPHNDF_00408 2.7e-76 atkY K Penicillinase repressor
COEPHNDF_00409 2.3e-35
COEPHNDF_00410 6.7e-224 pbuG S permease
COEPHNDF_00411 1.1e-167 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
COEPHNDF_00412 1.8e-136 fruR K DeoR C terminal sensor domain
COEPHNDF_00415 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
COEPHNDF_00416 5.6e-26
COEPHNDF_00417 2.1e-32
COEPHNDF_00418 3.9e-34 yozG K Transcriptional regulator
COEPHNDF_00419 3.2e-37 S Enterocin A Immunity
COEPHNDF_00420 7.5e-14 S Enterocin A Immunity
COEPHNDF_00421 1.4e-211 S Archaea bacterial proteins of unknown function
COEPHNDF_00422 7.2e-146 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
COEPHNDF_00423 3.2e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COEPHNDF_00424 1.2e-208 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
COEPHNDF_00425 1.5e-121 K response regulator
COEPHNDF_00426 0.0 V ABC transporter
COEPHNDF_00427 1.2e-297 V ABC transporter, ATP-binding protein
COEPHNDF_00428 2e-138 XK27_01040 S Protein of unknown function (DUF1129)
COEPHNDF_00429 6.1e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COEPHNDF_00430 3.7e-44 yyzM S Bacterial protein of unknown function (DUF951)
COEPHNDF_00431 8.5e-154 spo0J K Belongs to the ParB family
COEPHNDF_00432 5.4e-136 soj D Sporulation initiation inhibitor
COEPHNDF_00433 3.9e-148 noc K Belongs to the ParB family
COEPHNDF_00434 1.8e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
COEPHNDF_00435 7.3e-84 cvpA S Colicin V production protein
COEPHNDF_00436 3.8e-181 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COEPHNDF_00437 1.1e-147 3.1.3.48 T Tyrosine phosphatase family
COEPHNDF_00438 3.5e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
COEPHNDF_00439 5.4e-95 nqr 1.5.1.36 S NADPH-dependent FMN reductase
COEPHNDF_00440 4.5e-109 K WHG domain
COEPHNDF_00441 8e-38
COEPHNDF_00442 4.1e-275 pipD E Dipeptidase
COEPHNDF_00443 2.4e-116 devA 3.6.3.25 V ABC transporter, ATP-binding protein
COEPHNDF_00444 5.4e-163 hrtB V ABC transporter permease
COEPHNDF_00445 7e-95 ygfC K Bacterial regulatory proteins, tetR family
COEPHNDF_00446 1.2e-111 G phosphoglycerate mutase
COEPHNDF_00447 1.9e-138 aroD S Alpha/beta hydrolase family
COEPHNDF_00448 6.4e-142 S Belongs to the UPF0246 family
COEPHNDF_00449 1.2e-120
COEPHNDF_00450 3.1e-49 2.7.7.12 C Domain of unknown function (DUF4931)
COEPHNDF_00451 3.7e-10
COEPHNDF_00452 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
COEPHNDF_00453 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COEPHNDF_00454 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
COEPHNDF_00455 9.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COEPHNDF_00456 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COEPHNDF_00457 9.3e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COEPHNDF_00458 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COEPHNDF_00459 5.4e-108 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COEPHNDF_00460 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COEPHNDF_00461 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
COEPHNDF_00462 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COEPHNDF_00463 1.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COEPHNDF_00464 1.7e-32 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COEPHNDF_00465 3.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COEPHNDF_00466 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COEPHNDF_00467 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COEPHNDF_00468 9.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COEPHNDF_00469 2.8e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COEPHNDF_00470 1.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COEPHNDF_00471 2.3e-24 rpmD J Ribosomal protein L30
COEPHNDF_00472 1.5e-71 rplO J Binds to the 23S rRNA
COEPHNDF_00473 4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COEPHNDF_00474 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COEPHNDF_00475 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COEPHNDF_00476 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
COEPHNDF_00477 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COEPHNDF_00478 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COEPHNDF_00479 1.8e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COEPHNDF_00480 4e-60 rplQ J Ribosomal protein L17
COEPHNDF_00481 1.7e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COEPHNDF_00482 4e-150 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COEPHNDF_00483 1.8e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COEPHNDF_00484 1.7e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COEPHNDF_00485 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COEPHNDF_00486 7.9e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
COEPHNDF_00487 5.5e-47 S Protein of unknown function (DUF805)
COEPHNDF_00488 3e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
COEPHNDF_00489 2.7e-112 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
COEPHNDF_00490 1.9e-133 S membrane transporter protein
COEPHNDF_00491 2e-126 pgm3 G Belongs to the phosphoglycerate mutase family
COEPHNDF_00492 6e-163 czcD P cation diffusion facilitator family transporter
COEPHNDF_00493 5.5e-23
COEPHNDF_00494 8.3e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COEPHNDF_00495 1.6e-182 S AAA domain
COEPHNDF_00496 6.2e-105 L transposase, IS605 OrfB family
COEPHNDF_00497 8.1e-114 L transposase, IS605 OrfB family
COEPHNDF_00498 0.0 mgtA 3.6.3.2, 3.6.3.6 P COG0474 Cation transport ATPase
COEPHNDF_00499 2.3e-09
COEPHNDF_00500 1.1e-145 glcU U sugar transport
COEPHNDF_00501 3.6e-265 pepC 3.4.22.40 E Peptidase C1-like family
COEPHNDF_00502 6.2e-211 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COEPHNDF_00503 6e-157 S Alpha/beta hydrolase of unknown function (DUF915)
COEPHNDF_00504 0.0 clpE O AAA domain (Cdc48 subfamily)
COEPHNDF_00505 4.9e-119 lepB 3.4.21.89 U Belongs to the peptidase S26 family
COEPHNDF_00506 1.4e-128
COEPHNDF_00507 3.3e-216 cycA E Amino acid permease
COEPHNDF_00508 1.9e-245 yifK E Amino acid permease
COEPHNDF_00509 1.2e-137 puuD S peptidase C26
COEPHNDF_00510 1.8e-174 steT_1 E amino acid
COEPHNDF_00511 5.6e-50 steT_1 E amino acid
COEPHNDF_00512 2e-191 asnA 6.3.1.1 F aspartate--ammonia ligase
COEPHNDF_00513 9e-203 4.2.1.126 S Bacterial protein of unknown function (DUF871)
COEPHNDF_00516 1.3e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COEPHNDF_00517 1.6e-246 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COEPHNDF_00518 5.8e-244 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COEPHNDF_00519 6.1e-58
COEPHNDF_00520 2.9e-84
COEPHNDF_00521 3.4e-32 yheS_2 S ATPases associated with a variety of cellular activities
COEPHNDF_00522 2.1e-135 yheS_2 S ATPases associated with a variety of cellular activities
COEPHNDF_00523 2.7e-183 XK27_05540 S DUF218 domain
COEPHNDF_00524 6.9e-78
COEPHNDF_00525 5.5e-110
COEPHNDF_00526 7.8e-150 EG EamA-like transporter family
COEPHNDF_00527 9.5e-83 M NlpC/P60 family
COEPHNDF_00528 1.2e-131 cobQ S glutamine amidotransferase
COEPHNDF_00530 5.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COEPHNDF_00531 5.2e-229 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COEPHNDF_00532 3e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
COEPHNDF_00533 1.2e-174 yvdE K helix_turn _helix lactose operon repressor
COEPHNDF_00534 1e-111 ackA 2.7.2.1 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COEPHNDF_00535 1e-145 sufC O FeS assembly ATPase SufC
COEPHNDF_00536 3.2e-226 sufD O FeS assembly protein SufD
COEPHNDF_00537 1.5e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COEPHNDF_00538 4.2e-80 nifU C SUF system FeS assembly protein, NifU family
COEPHNDF_00539 1.9e-272 sufB O assembly protein SufB
COEPHNDF_00540 6.2e-54 yitW S Iron-sulfur cluster assembly protein
COEPHNDF_00541 5.4e-62 S Enterocin A Immunity
COEPHNDF_00542 7.1e-133 glcR K DeoR C terminal sensor domain
COEPHNDF_00543 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
COEPHNDF_00544 2.6e-160 rssA S Phospholipase, patatin family
COEPHNDF_00545 3.3e-11 2.7.13.3 T GHKL domain
COEPHNDF_00546 1.1e-85 S hydrolase
COEPHNDF_00547 0.0 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
COEPHNDF_00548 1.8e-136 glvR K Helix-turn-helix domain, rpiR family
COEPHNDF_00549 1.9e-73
COEPHNDF_00550 4.2e-86 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
COEPHNDF_00551 1.6e-39
COEPHNDF_00552 1.5e-14 C nitroreductase
COEPHNDF_00553 1.5e-30 C nitroreductase
COEPHNDF_00554 1.9e-237 yhdP S Transporter associated domain
COEPHNDF_00555 2.2e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COEPHNDF_00556 2.7e-214 potE E amino acid
COEPHNDF_00557 2.4e-127 M Glycosyl hydrolases family 25
COEPHNDF_00558 3.2e-207 yfmL 3.6.4.13 L DEAD DEAH box helicase
COEPHNDF_00559 5.4e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COEPHNDF_00561 2.7e-25
COEPHNDF_00562 5e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COEPHNDF_00563 1.8e-87 gtcA S Teichoic acid glycosylation protein
COEPHNDF_00564 1.6e-79 fld C Flavodoxin
COEPHNDF_00565 1.9e-163 map 3.4.11.18 E Methionine Aminopeptidase
COEPHNDF_00566 3.2e-151 yihY S Belongs to the UPF0761 family
COEPHNDF_00567 4.9e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COEPHNDF_00568 5.2e-15 L transposase, IS605 OrfB family
COEPHNDF_00570 4.8e-200 M Glycosyl hydrolases family 25
COEPHNDF_00571 0.0 S Predicted membrane protein (DUF2207)
COEPHNDF_00572 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
COEPHNDF_00573 9.5e-129 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
COEPHNDF_00574 1.5e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
COEPHNDF_00575 4.1e-256 S Uncharacterized protein conserved in bacteria (DUF2325)
COEPHNDF_00576 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
COEPHNDF_00577 1e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
COEPHNDF_00578 7.5e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COEPHNDF_00579 9.2e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COEPHNDF_00580 5.3e-69 yqhY S Asp23 family, cell envelope-related function
COEPHNDF_00581 1.4e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COEPHNDF_00582 4e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COEPHNDF_00583 1.5e-194 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COEPHNDF_00584 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COEPHNDF_00585 2.1e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COEPHNDF_00586 6.2e-151 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
COEPHNDF_00587 1.8e-306 recN L May be involved in recombinational repair of damaged DNA
COEPHNDF_00588 1.7e-78 6.3.3.2 S ASCH
COEPHNDF_00589 1.2e-109 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
COEPHNDF_00590 9.4e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COEPHNDF_00591 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COEPHNDF_00592 1.1e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COEPHNDF_00593 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COEPHNDF_00594 4.5e-146 stp 3.1.3.16 T phosphatase
COEPHNDF_00595 3.2e-296 prkC 2.7.11.1 KLT serine threonine protein kinase
COEPHNDF_00596 6.7e-31 prkC 2.7.11.1 KLT serine threonine protein kinase
COEPHNDF_00597 9.7e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COEPHNDF_00598 9.4e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
COEPHNDF_00599 8.4e-125 thiN 2.7.6.2 H thiamine pyrophosphokinase
COEPHNDF_00600 5.7e-49
COEPHNDF_00601 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
COEPHNDF_00602 6.8e-57 asp S Asp23 family, cell envelope-related function
COEPHNDF_00603 2.2e-304 yloV S DAK2 domain fusion protein YloV
COEPHNDF_00604 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COEPHNDF_00605 2.9e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COEPHNDF_00606 2.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COEPHNDF_00607 1.7e-193 oppD P Belongs to the ABC transporter superfamily
COEPHNDF_00608 5.3e-181 oppF P Belongs to the ABC transporter superfamily
COEPHNDF_00609 5e-176 oppB P ABC transporter permease
COEPHNDF_00610 2.9e-144 oppC P Binding-protein-dependent transport system inner membrane component
COEPHNDF_00611 0.0 oppA E ABC transporter substrate-binding protein
COEPHNDF_00612 0.0 oppA E ABC transporter substrate-binding protein
COEPHNDF_00613 1.3e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COEPHNDF_00614 0.0 smc D Required for chromosome condensation and partitioning
COEPHNDF_00615 4.9e-166 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COEPHNDF_00616 1.7e-289 pipD E Dipeptidase
COEPHNDF_00617 1.8e-44
COEPHNDF_00618 5.4e-259 yfnA E amino acid
COEPHNDF_00619 1.3e-75 L Transposase and inactivated derivatives, IS30 family
COEPHNDF_00620 3.2e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COEPHNDF_00621 2.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COEPHNDF_00622 4.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
COEPHNDF_00623 2.9e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COEPHNDF_00624 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
COEPHNDF_00625 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COEPHNDF_00626 9.2e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
COEPHNDF_00627 2.1e-148 E GDSL-like Lipase/Acylhydrolase family
COEPHNDF_00628 1.5e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COEPHNDF_00629 4.3e-37 ynzC S UPF0291 protein
COEPHNDF_00630 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
COEPHNDF_00631 1e-296 mdlA V ABC transporter
COEPHNDF_00632 1.2e-300 mdlB V ABC transporter
COEPHNDF_00633 0.0 pepO 3.4.24.71 O Peptidase family M13
COEPHNDF_00634 3.2e-225 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
COEPHNDF_00635 5.1e-113 plsC 2.3.1.51 I Acyltransferase
COEPHNDF_00636 8.6e-198 yabB 2.1.1.223 L Methyltransferase small domain
COEPHNDF_00637 1.2e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
COEPHNDF_00638 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COEPHNDF_00639 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
COEPHNDF_00640 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COEPHNDF_00641 7.8e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COEPHNDF_00642 1.6e-146 cdsA 2.7.7.41 I Belongs to the CDS family
COEPHNDF_00643 1.5e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
COEPHNDF_00644 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COEPHNDF_00645 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COEPHNDF_00646 5.5e-83 rimP J Required for maturation of 30S ribosomal subunits
COEPHNDF_00647 4.6e-195 nusA K Participates in both transcription termination and antitermination
COEPHNDF_00648 3e-47 ylxR K Protein of unknown function (DUF448)
COEPHNDF_00649 1e-45 rplGA J ribosomal protein
COEPHNDF_00650 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COEPHNDF_00651 3.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COEPHNDF_00652 9.8e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COEPHNDF_00653 2.3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
COEPHNDF_00654 4.5e-186 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COEPHNDF_00655 8.2e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COEPHNDF_00656 0.0 dnaK O Heat shock 70 kDa protein
COEPHNDF_00657 3.9e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COEPHNDF_00659 5.4e-95 L helicase activity
COEPHNDF_00660 2.8e-61
COEPHNDF_00661 2.1e-96 MA20_25245 K Acetyltransferase (GNAT) domain
COEPHNDF_00666 1.6e-242 emrY EGP Major facilitator Superfamily
COEPHNDF_00667 4.5e-91 yxdD K Bacterial regulatory proteins, tetR family
COEPHNDF_00668 6.7e-165 4.2.1.53 S Myosin-crossreactive antigen
COEPHNDF_00669 3.5e-154 4.2.1.53 S Myosin-crossreactive antigen
COEPHNDF_00670 9.9e-85 2.3.1.128 K acetyltransferase
COEPHNDF_00671 6.6e-145 G PTS system mannose/fructose/sorbose family IID component
COEPHNDF_00672 3.4e-41 G PTS system sorbose-specific iic component
COEPHNDF_00673 4e-73 G PTS system sorbose-specific iic component
COEPHNDF_00674 9.5e-78 2.7.1.191 G PTS system sorbose subfamily IIB component
COEPHNDF_00675 1.7e-29 2.7.1.191 G phosphoenolpyruvate-dependent sugar phosphotransferase system
COEPHNDF_00676 3.6e-154 S reductase
COEPHNDF_00677 1.7e-238 pyrP F Permease
COEPHNDF_00678 7.5e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COEPHNDF_00679 2.1e-258 emrY EGP Major facilitator Superfamily
COEPHNDF_00680 2.3e-168 mdtG EGP Major facilitator Superfamily
COEPHNDF_00681 5.7e-33 mdtG EGP Major facilitator Superfamily
COEPHNDF_00682 7.8e-210 pepA E M42 glutamyl aminopeptidase
COEPHNDF_00683 5.8e-310 ybiT S ABC transporter, ATP-binding protein
COEPHNDF_00684 9.9e-146
COEPHNDF_00685 4.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
COEPHNDF_00686 5.5e-147 glnH ET ABC transporter
COEPHNDF_00687 2.2e-79 K Transcriptional regulator, MarR family
COEPHNDF_00688 2.2e-291 XK27_09600 V ABC transporter, ATP-binding protein
COEPHNDF_00689 0.0 V ABC transporter transmembrane region
COEPHNDF_00690 2.4e-101 S ABC-type cobalt transport system, permease component
COEPHNDF_00691 2.2e-94 EGP Major facilitator superfamily
COEPHNDF_00692 4.2e-63 EGP Major facilitator superfamily
COEPHNDF_00693 2.1e-81 udk 2.7.1.48 F Zeta toxin
COEPHNDF_00694 1.3e-16 udk 2.7.1.48 F Zeta toxin
COEPHNDF_00695 7.8e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
COEPHNDF_00696 5.2e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COEPHNDF_00697 1.7e-229 S Tetratricopeptide repeat protein
COEPHNDF_00698 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COEPHNDF_00699 3.7e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
COEPHNDF_00700 9.1e-207 rpsA 1.17.7.4 J Ribosomal protein S1
COEPHNDF_00701 4.5e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
COEPHNDF_00702 3.4e-29 yocH M Lysin motif
COEPHNDF_00703 1.2e-115 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COEPHNDF_00704 8.5e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COEPHNDF_00705 9.2e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COEPHNDF_00706 7.2e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COEPHNDF_00707 4.9e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COEPHNDF_00708 2.6e-166 xerD D recombinase XerD
COEPHNDF_00709 1.6e-168 cvfB S S1 domain
COEPHNDF_00710 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
COEPHNDF_00711 6.6e-184 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
COEPHNDF_00712 0.0 dnaE 2.7.7.7 L DNA polymerase
COEPHNDF_00713 2.5e-22 S Protein of unknown function (DUF2929)
COEPHNDF_00714 1.3e-306 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
COEPHNDF_00715 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
COEPHNDF_00716 6.2e-33 yrvD S Lipopolysaccharide assembly protein A domain
COEPHNDF_00717 6.1e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COEPHNDF_00718 9.9e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COEPHNDF_00719 0.0 oatA I Acyltransferase
COEPHNDF_00720 1.4e-242 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COEPHNDF_00721 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COEPHNDF_00722 2.9e-90
COEPHNDF_00725 8.5e-196 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
COEPHNDF_00726 1.8e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COEPHNDF_00727 6.9e-273 yjeM E Amino Acid
COEPHNDF_00728 3.9e-39
COEPHNDF_00729 1.7e-60
COEPHNDF_00730 7.1e-88
COEPHNDF_00731 2.2e-26
COEPHNDF_00732 3.1e-07
COEPHNDF_00733 5.1e-125 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
COEPHNDF_00734 9.2e-71 O OsmC-like protein
COEPHNDF_00735 2.1e-208 EGP Major facilitator Superfamily
COEPHNDF_00736 6.1e-116 sptS 2.7.13.3 T Histidine kinase
COEPHNDF_00737 1.3e-50 sptS 2.7.13.3 T Histidine kinase
COEPHNDF_00738 5.5e-81 K response regulator
COEPHNDF_00739 2.2e-142 L An automated process has identified a potential problem with this gene model
COEPHNDF_00740 5.9e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
COEPHNDF_00741 2.2e-287 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
COEPHNDF_00742 3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
COEPHNDF_00743 3e-61 psiE S Phosphate-starvation-inducible E
COEPHNDF_00744 5.8e-214 Q Imidazolonepropionase and related amidohydrolases
COEPHNDF_00745 3.9e-290 oppA E ABC transporter
COEPHNDF_00746 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
COEPHNDF_00747 1.2e-217 naiP EGP Major facilitator Superfamily
COEPHNDF_00748 6.2e-66 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
COEPHNDF_00749 1.4e-53
COEPHNDF_00750 1.2e-46
COEPHNDF_00751 1.8e-164 hprA 1.1.1.29 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEPHNDF_00752 8e-114
COEPHNDF_00753 1.3e-17 L helicase
COEPHNDF_00754 0.0 S Protein of unknown function DUF262
COEPHNDF_00755 1.4e-16
COEPHNDF_00756 2.4e-30
COEPHNDF_00757 1.8e-59 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COEPHNDF_00758 2e-109 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
COEPHNDF_00759 1e-88 dps P Belongs to the Dps family
COEPHNDF_00760 3.6e-32 copZ C Heavy-metal-associated domain
COEPHNDF_00761 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
COEPHNDF_00762 1.3e-49 mepA V MATE efflux family protein
COEPHNDF_00763 1.7e-20 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
COEPHNDF_00764 7.7e-263 npr 1.11.1.1 C NADH oxidase
COEPHNDF_00765 5.3e-68 S pyridoxamine 5-phosphate
COEPHNDF_00766 4.7e-171 yobV1 K WYL domain
COEPHNDF_00767 1.4e-80 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
COEPHNDF_00768 4.5e-34
COEPHNDF_00769 2.2e-82 S An automated process has identified a potential problem with this gene model
COEPHNDF_00770 1e-140 S Protein of unknown function (DUF3100)
COEPHNDF_00771 5.5e-247 3.5.1.47 S Peptidase dimerisation domain
COEPHNDF_00772 2.5e-54 4.4.1.5 E lactoylglutathione lyase activity
COEPHNDF_00773 1.4e-65 S ASCH domain
COEPHNDF_00774 3.8e-107 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COEPHNDF_00775 4.7e-81
COEPHNDF_00776 2.1e-304
COEPHNDF_00777 2e-97 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
COEPHNDF_00778 1.2e-68 L COG3385 FOG Transposase and inactivated derivatives
COEPHNDF_00779 7.5e-108 V Transport permease protein
COEPHNDF_00780 2e-124 V Transport permease protein
COEPHNDF_00781 1.3e-134 CP ATPases associated with a variety of cellular activities
COEPHNDF_00782 6e-29
COEPHNDF_00783 2.4e-37
COEPHNDF_00784 1e-290 V ABC transporter transmembrane region
COEPHNDF_00785 9.5e-38 KLT serine threonine protein kinase
COEPHNDF_00786 1.8e-290 V ABC transporter transmembrane region
COEPHNDF_00787 4.1e-119
COEPHNDF_00788 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
COEPHNDF_00789 0.0 pepO 3.4.24.71 O Peptidase family M13
COEPHNDF_00790 3.3e-59 pdxH S Pyridoxamine 5'-phosphate oxidase
COEPHNDF_00791 6.5e-58 steT E amino acid
COEPHNDF_00792 6.7e-16 mmuP E amino acid
COEPHNDF_00793 1.7e-33 mmuP E amino acid
COEPHNDF_00794 5.8e-241 N Uncharacterized conserved protein (DUF2075)
COEPHNDF_00795 1.4e-27 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
COEPHNDF_00796 6.1e-87 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
COEPHNDF_00797 2.2e-207
COEPHNDF_00798 7.1e-257 S C4-dicarboxylate anaerobic carrier
COEPHNDF_00799 7.4e-92 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COEPHNDF_00800 4.7e-102 S LexA-binding, inner membrane-associated putative hydrolase
COEPHNDF_00801 3e-37
COEPHNDF_00802 2.1e-121 malY 4.4.1.8 E Aminotransferase, class I
COEPHNDF_00803 1.2e-37 malY 4.4.1.8 E Aminotransferase, class I
COEPHNDF_00804 2.6e-55
COEPHNDF_00805 6.4e-241 brnQ U Component of the transport system for branched-chain amino acids
COEPHNDF_00806 2e-68 S Protein of unknown function (DUF554)
COEPHNDF_00807 1.2e-13 S Protein of unknown function (DUF554)
COEPHNDF_00808 4.5e-45 K LysR substrate binding domain
COEPHNDF_00809 7.4e-243 ubiX 2.5.1.129, 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
COEPHNDF_00810 5.3e-28 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
COEPHNDF_00811 6.5e-22
COEPHNDF_00812 3.7e-82 tdh 1.1.1.14 C Zinc-binding dehydrogenase
COEPHNDF_00813 2.2e-85 tdh 1.1.1.14 C Zinc-binding dehydrogenase
COEPHNDF_00815 3.8e-68 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
COEPHNDF_00816 3e-68 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
COEPHNDF_00817 1.4e-43 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
COEPHNDF_00818 9.6e-106 L An automated process has identified a potential problem with this gene model
COEPHNDF_00819 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
COEPHNDF_00820 2.5e-247 ynbB 4.4.1.1 P aluminum resistance
COEPHNDF_00821 2.3e-78 ktrB P Potassium uptake protein
COEPHNDF_00822 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
COEPHNDF_00823 1.7e-78 C Flavodoxin
COEPHNDF_00824 1.3e-111 3.6.1.27 I Acid phosphatase homologues
COEPHNDF_00825 2.7e-106 lacA 2.3.1.79 S Transferase hexapeptide repeat
COEPHNDF_00826 8.2e-207 pbpX1 V Beta-lactamase
COEPHNDF_00827 1.2e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
COEPHNDF_00828 5.8e-92 S ECF-type riboflavin transporter, S component
COEPHNDF_00829 8.1e-232 S Putative peptidoglycan binding domain
COEPHNDF_00830 3.5e-236 mepA V MATE efflux family protein
COEPHNDF_00831 1e-256 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
COEPHNDF_00832 1.9e-33
COEPHNDF_00833 2.3e-29 fic D Fic/DOC family
COEPHNDF_00834 2.2e-60
COEPHNDF_00835 9e-295 P ABC transporter
COEPHNDF_00836 2.6e-294 V ABC-type multidrug transport system, ATPase and permease components
COEPHNDF_00837 9.2e-69 S Putative adhesin
COEPHNDF_00838 1.3e-58 ypaA S Protein of unknown function (DUF1304)
COEPHNDF_00840 3.3e-78
COEPHNDF_00841 2.4e-56
COEPHNDF_00842 2.9e-116 S Fic/DOC family
COEPHNDF_00843 1.7e-102
COEPHNDF_00844 6.1e-208 EGP Major facilitator Superfamily
COEPHNDF_00845 5.4e-135
COEPHNDF_00847 1.6e-28 cspA K Cold shock protein
COEPHNDF_00848 3e-259 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
COEPHNDF_00849 1.4e-170 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
COEPHNDF_00850 1.5e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COEPHNDF_00851 1e-246 nhaC C Na H antiporter NhaC
COEPHNDF_00852 3.5e-55
COEPHNDF_00853 1.1e-119 ybhL S Belongs to the BI1 family
COEPHNDF_00854 4.7e-115 S Protein of unknown function (DUF1211)
COEPHNDF_00855 3e-170 yegS 2.7.1.107 G Lipid kinase
COEPHNDF_00856 2.9e-276 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COEPHNDF_00857 2.2e-260 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COEPHNDF_00858 5.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COEPHNDF_00859 3e-207 camS S sex pheromone
COEPHNDF_00860 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COEPHNDF_00861 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
COEPHNDF_00862 2e-104 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
COEPHNDF_00864 5.3e-86 ydcK S Belongs to the SprT family
COEPHNDF_00865 1.7e-136 M Glycosyltransferase sugar-binding region containing DXD motif
COEPHNDF_00866 2.4e-259 epsU S Polysaccharide biosynthesis protein
COEPHNDF_00867 4.7e-224 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
COEPHNDF_00868 0.0 pacL 3.6.3.8 P P-type ATPase
COEPHNDF_00869 4.8e-57 pacL 3.6.3.8 P P-type ATPase
COEPHNDF_00871 3.6e-168 psaA P Belongs to the bacterial solute-binding protein 9 family
COEPHNDF_00874 2.5e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COEPHNDF_00875 7e-262 qacA EGP Major facilitator Superfamily
COEPHNDF_00876 1.1e-149 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COEPHNDF_00877 1.3e-119 3.6.1.27 I Acid phosphatase homologues
COEPHNDF_00878 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
COEPHNDF_00879 1.3e-296 ytgP S Polysaccharide biosynthesis protein
COEPHNDF_00880 2.2e-182 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
COEPHNDF_00881 3e-91 dhaL 2.7.1.121 S Dak2
COEPHNDF_00882 1.3e-55 dhaM 2.7.1.121 S PTS system fructose IIA component
COEPHNDF_00883 6.7e-49
COEPHNDF_00884 8.5e-226 O Belongs to the peptidase S8 family
COEPHNDF_00885 6.7e-93 O Belongs to the peptidase S8 family
COEPHNDF_00886 1.2e-63 O Belongs to the peptidase S8 family
COEPHNDF_00887 5.8e-72 infB UW LPXTG-motif cell wall anchor domain protein
COEPHNDF_00888 1.7e-15 infB UW LPXTG-motif cell wall anchor domain protein
COEPHNDF_00889 1.7e-22 UW LPXTG-motif cell wall anchor domain protein
COEPHNDF_00890 2.1e-20
COEPHNDF_00891 5.2e-36 CO Thioredoxin
COEPHNDF_00892 7.2e-118 M1-798 K Rhodanese Homology Domain
COEPHNDF_00893 7.7e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COEPHNDF_00894 2.3e-37 frnE Q DSBA-like thioredoxin domain
COEPHNDF_00895 1.2e-25 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COEPHNDF_00896 2.7e-148
COEPHNDF_00897 1.4e-164
COEPHNDF_00898 1.8e-135
COEPHNDF_00899 3.4e-263 glnA 6.3.1.2 E glutamine synthetase
COEPHNDF_00900 1.3e-168 ynbB 4.4.1.1 P aluminum resistance
COEPHNDF_00901 2.6e-30 ynbB 4.4.1.1 P aluminum resistance
COEPHNDF_00902 3.6e-171 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COEPHNDF_00903 4.5e-70 yqhL P Rhodanese-like protein
COEPHNDF_00904 5.6e-33 yqgQ S Bacterial protein of unknown function (DUF910)
COEPHNDF_00905 3.2e-116 gluP 3.4.21.105 S Rhomboid family
COEPHNDF_00906 1.7e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COEPHNDF_00907 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COEPHNDF_00908 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
COEPHNDF_00909 0.0 S membrane
COEPHNDF_00910 1.5e-169 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
COEPHNDF_00911 9e-38 K Helix-turn-helix domain
COEPHNDF_00912 2.8e-26 S Phage derived protein Gp49-like (DUF891)
COEPHNDF_00913 1.6e-168 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
COEPHNDF_00914 9.2e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COEPHNDF_00915 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COEPHNDF_00916 2e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COEPHNDF_00917 1.5e-61 yodB K Transcriptional regulator, HxlR family
COEPHNDF_00918 1.5e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COEPHNDF_00919 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
COEPHNDF_00920 4.9e-155 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COEPHNDF_00921 1e-84 S Aminoacyl-tRNA editing domain
COEPHNDF_00922 8.5e-102 tnpR L Resolvase, N terminal domain
COEPHNDF_00923 2.8e-131 S Phage Mu protein F like protein
COEPHNDF_00924 1.2e-12 ytgB S Transglycosylase associated protein
COEPHNDF_00925 5.2e-124 tnp L DDE domain
COEPHNDF_00926 3.4e-56 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
COEPHNDF_00927 2.2e-125 L Transposase DDE domain
COEPHNDF_00930 7.6e-157 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COEPHNDF_00931 1.1e-159 dnaQ 2.7.7.7 L EXOIII
COEPHNDF_00932 8.5e-159 endA F DNA RNA non-specific endonuclease
COEPHNDF_00933 5e-281 pipD E Dipeptidase
COEPHNDF_00934 3.9e-201 malK P ATPases associated with a variety of cellular activities
COEPHNDF_00935 8e-157 gtsB P ABC-type sugar transport systems, permease components
COEPHNDF_00936 4.7e-146 gtsC P Binding-protein-dependent transport system inner membrane component
COEPHNDF_00937 1.5e-255 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
COEPHNDF_00938 1.8e-240 G Bacterial extracellular solute-binding protein
COEPHNDF_00939 5.3e-159 corA P CorA-like Mg2+ transporter protein
COEPHNDF_00940 4e-157 3.5.2.6 V Beta-lactamase enzyme family
COEPHNDF_00941 3.3e-98 yobS K Bacterial regulatory proteins, tetR family
COEPHNDF_00942 0.0 ydgH S MMPL family
COEPHNDF_00943 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
COEPHNDF_00944 2.3e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COEPHNDF_00945 5e-157 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COEPHNDF_00946 9.5e-80 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COEPHNDF_00947 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
COEPHNDF_00948 1.2e-200 cpdA S Calcineurin-like phosphoesterase
COEPHNDF_00949 2.9e-215 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
COEPHNDF_00950 8e-70 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
COEPHNDF_00951 8.6e-107 ypsA S Belongs to the UPF0398 family
COEPHNDF_00952 3.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COEPHNDF_00953 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
COEPHNDF_00954 5.1e-113 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COEPHNDF_00955 7.4e-115 dnaD L DnaD domain protein
COEPHNDF_00956 1.2e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
COEPHNDF_00957 1.1e-89 ypmB S Protein conserved in bacteria
COEPHNDF_00958 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
COEPHNDF_00959 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
COEPHNDF_00960 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
COEPHNDF_00961 1.1e-167 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
COEPHNDF_00962 2.2e-179 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
COEPHNDF_00963 4.2e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
COEPHNDF_00964 8.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
COEPHNDF_00965 2.8e-260 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
COEPHNDF_00966 1.8e-176
COEPHNDF_00967 2.7e-140
COEPHNDF_00968 3e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
COEPHNDF_00969 7.8e-28
COEPHNDF_00970 9.8e-115 rarA L recombination factor protein RarA
COEPHNDF_00971 4.9e-10 rarA L recombination factor protein RarA
COEPHNDF_00972 1.6e-129
COEPHNDF_00973 1.1e-147
COEPHNDF_00974 1.6e-146
COEPHNDF_00975 2.8e-123 skfE V ATPases associated with a variety of cellular activities
COEPHNDF_00976 3.9e-60 yvoA_1 K Transcriptional regulator, GntR family
COEPHNDF_00977 1.4e-242 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
COEPHNDF_00978 1e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COEPHNDF_00979 2.4e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
COEPHNDF_00980 3.6e-68 mutT 3.6.1.55 F NUDIX domain
COEPHNDF_00981 6.8e-124 S Peptidase family M23
COEPHNDF_00982 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COEPHNDF_00983 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COEPHNDF_00984 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
COEPHNDF_00985 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
COEPHNDF_00986 1e-136 recO L Involved in DNA repair and RecF pathway recombination
COEPHNDF_00987 6.9e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COEPHNDF_00988 7.2e-92 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COEPHNDF_00989 8.9e-173 phoH T phosphate starvation-inducible protein PhoH
COEPHNDF_00990 3.2e-69 yqeY S YqeY-like protein
COEPHNDF_00991 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
COEPHNDF_00992 6.8e-153 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
COEPHNDF_00993 1.4e-111 S Peptidase family M23
COEPHNDF_00994 1.4e-161 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COEPHNDF_00995 1.5e-107
COEPHNDF_00996 8.6e-110 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
COEPHNDF_00997 1.6e-122 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
COEPHNDF_00998 7.1e-246 thrC 4.2.3.1 E Threonine synthase
COEPHNDF_00999 1.5e-186 lysC 2.7.2.4 E Belongs to the aspartokinase family
COEPHNDF_01001 7e-115 3.6.3.44 V ABC transporter transmembrane region
COEPHNDF_01002 7.9e-28 S amino acid activation for nonribosomal peptide biosynthetic process
COEPHNDF_01003 2.4e-74
COEPHNDF_01004 5.9e-106 K LysR substrate binding domain
COEPHNDF_01005 2.5e-19
COEPHNDF_01006 3.1e-212 S Sterol carrier protein domain
COEPHNDF_01007 8.4e-96 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
COEPHNDF_01008 2.8e-52 arcC 2.7.2.2 E Belongs to the carbamate kinase family
COEPHNDF_01009 5.3e-69 arcC 2.7.2.2 E Belongs to the carbamate kinase family
COEPHNDF_01010 1.5e-144 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COEPHNDF_01011 1.1e-12 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COEPHNDF_01012 7.1e-90 arcA 3.5.3.6 E Arginine
COEPHNDF_01013 6.6e-15 arcA 3.5.3.6 E Arginine
COEPHNDF_01014 7.1e-22 arcA 3.5.3.6 E Arginine
COEPHNDF_01015 5.1e-156 lysR5 K LysR substrate binding domain
COEPHNDF_01016 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
COEPHNDF_01017 2.4e-84 3.4.21.96 S SLAP domain
COEPHNDF_01018 3.3e-97 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COEPHNDF_01019 9.4e-110 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COEPHNDF_01020 2.1e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
COEPHNDF_01021 4.4e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COEPHNDF_01022 1.8e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COEPHNDF_01023 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
COEPHNDF_01024 7.6e-118 srtA 3.4.22.70 M sortase family
COEPHNDF_01025 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COEPHNDF_01026 3.8e-15
COEPHNDF_01027 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
COEPHNDF_01028 9.2e-201 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
COEPHNDF_01029 1.2e-216 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
COEPHNDF_01030 4e-286 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
COEPHNDF_01031 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
COEPHNDF_01032 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
COEPHNDF_01033 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
COEPHNDF_01034 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COEPHNDF_01035 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COEPHNDF_01036 9.1e-82 S Short repeat of unknown function (DUF308)
COEPHNDF_01037 1.4e-164 rapZ S Displays ATPase and GTPase activities
COEPHNDF_01038 2.9e-193 ybhK S Required for morphogenesis under gluconeogenic growth conditions
COEPHNDF_01039 1.1e-170 whiA K May be required for sporulation
COEPHNDF_01040 2.1e-260 pgi 5.3.1.9 G Belongs to the GPI family
COEPHNDF_01041 8.3e-108 vanZ V VanZ like family
COEPHNDF_01042 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COEPHNDF_01043 4.1e-270 yclK 2.7.13.3 T Histidine kinase
COEPHNDF_01044 1.6e-129 K Transcriptional regulatory protein, C terminal
COEPHNDF_01045 2.4e-60 S SdpI/YhfL protein family
COEPHNDF_01046 8.6e-168 manA 5.3.1.8 G mannose-6-phosphate isomerase
COEPHNDF_01047 2.4e-225 patB 4.4.1.8 E Aminotransferase, class I
COEPHNDF_01048 2.1e-32 M Protein of unknown function (DUF3737)
COEPHNDF_01049 2.4e-34 M Protein of unknown function (DUF3737)
COEPHNDF_01051 6.8e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COEPHNDF_01052 1.1e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
COEPHNDF_01053 8.4e-82 comGF U Putative Competence protein ComGF
COEPHNDF_01054 1e-41
COEPHNDF_01055 2.1e-73
COEPHNDF_01056 3.7e-44 comGC U competence protein ComGC
COEPHNDF_01057 7.6e-175 comGB NU type II secretion system
COEPHNDF_01058 1e-176 comGA NU Type II IV secretion system protein
COEPHNDF_01059 8.9e-133 yebC K Transcriptional regulatory protein
COEPHNDF_01060 4.6e-91 S VanZ like family
COEPHNDF_01061 1.3e-201 L COG2826 Transposase and inactivated derivatives, IS30 family
COEPHNDF_01062 1.5e-67 L transposase, IS605 OrfB family
COEPHNDF_01063 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COEPHNDF_01064 4e-150 glnH ET ABC transporter substrate-binding protein
COEPHNDF_01065 1.5e-107 gluC P ABC transporter permease
COEPHNDF_01066 2.2e-106 glnP P ABC transporter permease
COEPHNDF_01067 2.4e-151 S Protein of unknown function (DUF2974)
COEPHNDF_01068 1.5e-130 K sequence-specific DNA binding
COEPHNDF_01069 2.9e-165 S SLAP domain
COEPHNDF_01070 2.7e-60 S Bacteriocin helveticin-J
COEPHNDF_01071 1.6e-233 G Bacterial extracellular solute-binding protein
COEPHNDF_01072 3.2e-160 2.7.7.12 C Domain of unknown function (DUF4931)
COEPHNDF_01073 5.9e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COEPHNDF_01074 2.6e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
COEPHNDF_01075 0.0 kup P Transport of potassium into the cell
COEPHNDF_01076 4.8e-176 rihB 3.2.2.1 F Nucleoside
COEPHNDF_01077 5.7e-132 gntR K UbiC transcription regulator-associated domain protein
COEPHNDF_01078 3.7e-17 ropB K Helix-turn-helix domain
COEPHNDF_01079 1.2e-61 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
COEPHNDF_01080 3.8e-54 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
COEPHNDF_01081 3e-153 S hydrolase
COEPHNDF_01082 1.4e-193 S SLAP domain
COEPHNDF_01083 5.1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COEPHNDF_01084 6.5e-149 GK ROK family
COEPHNDF_01085 5.5e-43
COEPHNDF_01086 4.7e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
COEPHNDF_01087 3.6e-67 S Domain of unknown function (DUF1934)
COEPHNDF_01088 1.5e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
COEPHNDF_01089 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COEPHNDF_01090 3.1e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COEPHNDF_01091 3.7e-33 S Haloacid dehalogenase-like hydrolase
COEPHNDF_01092 1.7e-48 S Haloacid dehalogenase-like hydrolase
COEPHNDF_01093 1.7e-284 pipD E Dipeptidase
COEPHNDF_01094 5.3e-158 msmR K AraC-like ligand binding domain
COEPHNDF_01095 4.9e-219 pbuX F xanthine permease
COEPHNDF_01096 7.4e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COEPHNDF_01097 8.3e-113 K DNA-binding helix-turn-helix protein
COEPHNDF_01098 4.7e-21 K Helix-turn-helix
COEPHNDF_01099 4.9e-17 K Helix-turn-helix
COEPHNDF_01100 6.6e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
COEPHNDF_01101 6.6e-82 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
COEPHNDF_01104 0.0 uvrA3 L excinuclease ABC, A subunit
COEPHNDF_01105 6.8e-95 yyaR K Acetyltransferase (GNAT) domain
COEPHNDF_01106 8.6e-38 mta K helix_turn_helix, mercury resistance
COEPHNDF_01107 2.2e-63 mta K helix_turn_helix, mercury resistance
COEPHNDF_01108 6.9e-07 S ParE toxin of type II toxin-antitoxin system, parDE
COEPHNDF_01109 1.3e-60 yyaQ S YjbR
COEPHNDF_01110 8.5e-87 proW P ABC transporter, permease protein
COEPHNDF_01111 3.8e-110 proV E ABC transporter, ATP-binding protein
COEPHNDF_01112 7e-89 proWZ P ABC transporter permease
COEPHNDF_01113 4.1e-143 proX M ABC transporter, substrate-binding protein, QAT family
COEPHNDF_01114 6.5e-124 C Zinc-binding dehydrogenase
COEPHNDF_01115 5.2e-49 S Membrane
COEPHNDF_01116 1.2e-87 S Membrane
COEPHNDF_01117 9.3e-25 I carboxylic ester hydrolase activity
COEPHNDF_01118 2.9e-62 4.2.99.20 S Alpha/beta hydrolase family
COEPHNDF_01119 2.2e-32 S Biotin synthase
COEPHNDF_01120 1.1e-28 S HicB family
COEPHNDF_01122 1.2e-58 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
COEPHNDF_01123 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
COEPHNDF_01124 4.9e-86 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
COEPHNDF_01125 1.9e-96 K Transcriptional regulator, AbiEi antitoxin
COEPHNDF_01126 3.8e-84 L Integrase
COEPHNDF_01127 1.9e-177 I Carboxylesterase family
COEPHNDF_01128 1.1e-64 arsC 1.20.4.1 P Belongs to the ArsC family
COEPHNDF_01129 4e-27
COEPHNDF_01130 2e-61 S Bacterial PH domain
COEPHNDF_01131 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
COEPHNDF_01132 2.5e-120 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
COEPHNDF_01133 4.4e-143 2.4.2.3 F Phosphorylase superfamily
COEPHNDF_01134 1.8e-144 2.4.2.3 F Phosphorylase superfamily
COEPHNDF_01135 2e-149 2.7.1.89 M Phosphotransferase enzyme family
COEPHNDF_01136 9e-92 S AAA domain
COEPHNDF_01137 5.2e-22 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
COEPHNDF_01138 4.3e-21 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
COEPHNDF_01139 6.4e-137 yxaM EGP Major facilitator Superfamily
COEPHNDF_01140 8e-51 3.6.1.55 F NUDIX domain
COEPHNDF_01141 2.9e-31 S Protein of unknown function (DUF3923)
COEPHNDF_01142 3.3e-43
COEPHNDF_01143 4e-57
COEPHNDF_01144 4.7e-26 S MazG-like family
COEPHNDF_01145 5.4e-147 S Protein of unknown function (DUF2785)
COEPHNDF_01146 1.4e-80 K Acetyltransferase (GNAT) domain
COEPHNDF_01147 3.4e-47
COEPHNDF_01148 2.3e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
COEPHNDF_01149 2.9e-47
COEPHNDF_01150 2.3e-43 glcU U sugar transport
COEPHNDF_01151 1.9e-84 glcU U sugar transport
COEPHNDF_01152 1.1e-64 S Domain of unknown function (DUF4411)
COEPHNDF_01153 3.3e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COEPHNDF_01154 4.2e-175 prmA J Ribosomal protein L11 methyltransferase
COEPHNDF_01155 8.5e-60
COEPHNDF_01156 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COEPHNDF_01157 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COEPHNDF_01158 3.1e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
COEPHNDF_01159 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
COEPHNDF_01160 3.4e-222 patA 2.6.1.1 E Aminotransferase
COEPHNDF_01161 3e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COEPHNDF_01162 1.2e-35 S reductase
COEPHNDF_01163 1.9e-74 S reductase
COEPHNDF_01164 3.4e-86 yxeH S hydrolase
COEPHNDF_01165 7e-27 yxeH S hydrolase
COEPHNDF_01166 2.3e-10 yxeH S hydrolase
COEPHNDF_01167 3.5e-14 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEPHNDF_01168 3.4e-78 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEPHNDF_01169 7.4e-43 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEPHNDF_01170 2.2e-249 yfnA E Amino Acid
COEPHNDF_01171 1.1e-75 dedA 3.1.3.1 S SNARE associated Golgi protein
COEPHNDF_01172 7.2e-75 S Uncharacterised protein family (UPF0236)
COEPHNDF_01173 3.5e-138 yxeH S hydrolase
COEPHNDF_01174 2.1e-36 S Enterocin A Immunity
COEPHNDF_01175 4.4e-225 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
COEPHNDF_01176 4.4e-49 pspC KT PspC domain
COEPHNDF_01178 1.1e-242 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COEPHNDF_01179 6.2e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COEPHNDF_01180 1.5e-110 M ErfK YbiS YcfS YnhG
COEPHNDF_01181 6.1e-91 padR K Virulence activator alpha C-term
COEPHNDF_01182 2e-102 padC Q Phenolic acid decarboxylase
COEPHNDF_01183 6.1e-111 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COEPHNDF_01184 2.2e-12 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COEPHNDF_01185 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
COEPHNDF_01186 3.5e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
COEPHNDF_01187 2.3e-90 3.6.1.55 L NUDIX domain
COEPHNDF_01188 2.1e-39
COEPHNDF_01189 1.7e-31
COEPHNDF_01190 3e-09 C WbqC-like protein family
COEPHNDF_01191 5.9e-180 S ABC transporter
COEPHNDF_01192 8.8e-110 S ABC-2 family transporter protein
COEPHNDF_01193 8.8e-142 S ABC-2 family transporter protein
COEPHNDF_01195 9.3e-45 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COEPHNDF_01196 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
COEPHNDF_01197 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
COEPHNDF_01198 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
COEPHNDF_01199 9.7e-118 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
COEPHNDF_01200 8.3e-207 msmX P Belongs to the ABC transporter superfamily
COEPHNDF_01201 1.6e-211 malE G Bacterial extracellular solute-binding protein
COEPHNDF_01202 2e-250 malF P Binding-protein-dependent transport system inner membrane component
COEPHNDF_01203 1.2e-152 malG P ABC transporter permease
COEPHNDF_01204 1e-42 ymdB S Macro domain protein
COEPHNDF_01205 4.5e-29 tnpR L Resolvase, N terminal domain
COEPHNDF_01207 6.1e-71 M domain protein
COEPHNDF_01208 1.2e-87 pbpX2 V Beta-lactamase
COEPHNDF_01209 2.5e-39 3.2.2.20 K acetyltransferase
COEPHNDF_01210 2.2e-96
COEPHNDF_01211 1.9e-46
COEPHNDF_01212 6.7e-41
COEPHNDF_01213 9.1e-63 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
COEPHNDF_01214 1.7e-195 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
COEPHNDF_01215 6.8e-131 glvR K Helix-turn-helix domain, rpiR family
COEPHNDF_01216 1.7e-187 ansA 3.5.1.1 EJ L-asparaginase, type I
COEPHNDF_01217 3.2e-15
COEPHNDF_01218 2.3e-19
COEPHNDF_01219 1.5e-25 3.6.3.8 P P-type ATPase
COEPHNDF_01220 2.3e-119 3.6.3.8 P P-type ATPase
COEPHNDF_01221 7e-124
COEPHNDF_01222 2.7e-238 S response to antibiotic
COEPHNDF_01223 1.4e-133 cysA V ABC transporter, ATP-binding protein
COEPHNDF_01224 0.0 V FtsX-like permease family
COEPHNDF_01225 3.4e-50 asdA 4.1.1.12 E Aminotransferase class I and II
COEPHNDF_01226 4.8e-151 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
COEPHNDF_01227 1.8e-116 dedA S SNARE-like domain protein
COEPHNDF_01228 2.2e-84 S Protein of unknown function (DUF1461)
COEPHNDF_01229 1.2e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
COEPHNDF_01230 3.3e-88 yutD S Protein of unknown function (DUF1027)
COEPHNDF_01231 6.2e-276 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
COEPHNDF_01232 1.1e-55
COEPHNDF_01233 5.9e-255 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
COEPHNDF_01234 1.1e-178 ccpA K catabolite control protein A
COEPHNDF_01235 8.3e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COEPHNDF_01236 2.6e-43
COEPHNDF_01237 3.3e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
COEPHNDF_01238 7.9e-149 ykuT M mechanosensitive ion channel
COEPHNDF_01239 7.1e-115 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COEPHNDF_01240 7.7e-146 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
COEPHNDF_01241 8.5e-69 yslB S Protein of unknown function (DUF2507)
COEPHNDF_01242 8.4e-39 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COEPHNDF_01243 4.6e-54 trxA O Belongs to the thioredoxin family
COEPHNDF_01244 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COEPHNDF_01245 1.4e-50 yrzB S Belongs to the UPF0473 family
COEPHNDF_01246 1e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COEPHNDF_01247 2e-42 yrzL S Belongs to the UPF0297 family
COEPHNDF_01248 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COEPHNDF_01249 1.2e-85
COEPHNDF_01250 7.1e-64
COEPHNDF_01251 4.4e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
COEPHNDF_01252 3e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
COEPHNDF_01253 1.3e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COEPHNDF_01254 4.2e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COEPHNDF_01255 2.9e-35 yajC U Preprotein translocase
COEPHNDF_01256 2.8e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COEPHNDF_01257 4.6e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COEPHNDF_01258 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COEPHNDF_01259 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COEPHNDF_01260 9.4e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COEPHNDF_01261 3e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COEPHNDF_01262 7.4e-89
COEPHNDF_01263 3.9e-47
COEPHNDF_01264 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
COEPHNDF_01265 3.2e-230 scrB 3.2.1.26 GH32 G invertase
COEPHNDF_01266 3.1e-181 scrR K Transcriptional regulator, LacI family
COEPHNDF_01267 2.5e-122 liaI S membrane
COEPHNDF_01268 9.6e-77 XK27_02470 K LytTr DNA-binding domain
COEPHNDF_01269 5.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COEPHNDF_01270 0.0 uup S ABC transporter, ATP-binding protein
COEPHNDF_01271 1.4e-12 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
COEPHNDF_01272 1.4e-216 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
COEPHNDF_01273 8.6e-38 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
COEPHNDF_01274 1.1e-113 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
COEPHNDF_01275 9e-108 yfdE 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
COEPHNDF_01276 3.7e-111 yfdE 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
COEPHNDF_01277 3.5e-27 S Toxin ToxN, type III toxin-antitoxin system
COEPHNDF_01278 2e-129 K UTRA
COEPHNDF_01279 1.4e-181 S Oxidoreductase family, NAD-binding Rossmann fold
COEPHNDF_01280 3.3e-124 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
COEPHNDF_01281 6.2e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COEPHNDF_01282 3.8e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
COEPHNDF_01283 5e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
COEPHNDF_01284 3.4e-86 S ECF transporter, substrate-specific component
COEPHNDF_01285 7.3e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
COEPHNDF_01286 1.3e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COEPHNDF_01287 4.5e-58 yabA L Involved in initiation control of chromosome replication
COEPHNDF_01288 4.8e-154 holB 2.7.7.7 L DNA polymerase III
COEPHNDF_01289 4.9e-51 yaaQ S Cyclic-di-AMP receptor
COEPHNDF_01290 8.7e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COEPHNDF_01291 2.6e-33 S Protein of unknown function (DUF2508)
COEPHNDF_01292 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COEPHNDF_01293 5e-38 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COEPHNDF_01294 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COEPHNDF_01295 6.9e-92 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COEPHNDF_01296 5e-116 rsmC 2.1.1.172 J Methyltransferase
COEPHNDF_01297 2.8e-72 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
COEPHNDF_01298 1.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COEPHNDF_01299 3.5e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COEPHNDF_01300 4.8e-155 yfdV S Membrane transport protein
COEPHNDF_01301 4.1e-10 yfdV S Membrane transport protein
COEPHNDF_01302 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
COEPHNDF_01303 7.8e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COEPHNDF_01304 9.3e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COEPHNDF_01305 3.5e-155 pstA P Phosphate transport system permease protein PstA
COEPHNDF_01306 1.9e-173 pstC P probably responsible for the translocation of the substrate across the membrane
COEPHNDF_01307 1.4e-156 pstS P Phosphate
COEPHNDF_01308 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COEPHNDF_01309 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COEPHNDF_01310 6.9e-101 nusG K Participates in transcription elongation, termination and antitermination
COEPHNDF_01311 5.9e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COEPHNDF_01312 1.9e-178 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COEPHNDF_01313 1.6e-112 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COEPHNDF_01314 1.3e-282 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
COEPHNDF_01315 8.3e-34
COEPHNDF_01316 8e-94 sigH K Belongs to the sigma-70 factor family
COEPHNDF_01317 7.8e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COEPHNDF_01318 7.9e-76 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COEPHNDF_01319 3.5e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
COEPHNDF_01320 1.5e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COEPHNDF_01321 1.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COEPHNDF_01322 9.5e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
COEPHNDF_01323 4.5e-54
COEPHNDF_01324 1.3e-51 S PAS domain
COEPHNDF_01325 4.5e-188 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
COEPHNDF_01326 0.0 L AAA domain
COEPHNDF_01327 7.7e-230 yhaO L Ser Thr phosphatase family protein
COEPHNDF_01328 3.6e-55 yheA S Belongs to the UPF0342 family
COEPHNDF_01329 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
COEPHNDF_01330 2.8e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COEPHNDF_01331 1.9e-09 5.3.3.2 C FMN-dependent dehydrogenase
COEPHNDF_01332 9.8e-46 mgtC S MgtC family
COEPHNDF_01333 1.5e-72 mgtC S MgtC family
COEPHNDF_01334 2.5e-138 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COEPHNDF_01335 4.9e-54
COEPHNDF_01336 2.6e-149 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
COEPHNDF_01337 5.5e-20 UW LPXTG-motif cell wall anchor domain protein
COEPHNDF_01339 2.3e-153 yitS S EDD domain protein, DegV family
COEPHNDF_01340 3.3e-83 racA K Domain of unknown function (DUF1836)
COEPHNDF_01341 2.1e-28 bioY S BioY family
COEPHNDF_01342 1.1e-189 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COEPHNDF_01343 1.9e-133 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
COEPHNDF_01344 4.1e-144 accA 2.1.3.15, 6.4.1.2 I alpha subunit
COEPHNDF_01345 6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COEPHNDF_01346 1.5e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
COEPHNDF_01347 1.7e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
COEPHNDF_01348 3.7e-79 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
COEPHNDF_01349 1.3e-229 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
COEPHNDF_01350 5.6e-127 IQ reductase
COEPHNDF_01351 3.7e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
COEPHNDF_01352 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COEPHNDF_01353 1.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COEPHNDF_01354 1.1e-78 marR K Transcriptional regulator
COEPHNDF_01355 3.8e-78 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COEPHNDF_01356 1.2e-25 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
COEPHNDF_01357 1.2e-16 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
COEPHNDF_01358 1.5e-95 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
COEPHNDF_01359 7e-13 ytgB S Transglycosylase associated protein
COEPHNDF_01360 1.5e-113 hlyIII S protein, hemolysin III
COEPHNDF_01361 8.5e-148 DegV S Uncharacterised protein, DegV family COG1307
COEPHNDF_01362 9.3e-36 yozE S Belongs to the UPF0346 family
COEPHNDF_01363 2.6e-278 yjcE P Sodium proton antiporter
COEPHNDF_01364 1.2e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COEPHNDF_01365 3.7e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COEPHNDF_01366 1.1e-155 dprA LU DNA protecting protein DprA
COEPHNDF_01367 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COEPHNDF_01368 4.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
COEPHNDF_01369 4.3e-169 xerC D Phage integrase, N-terminal SAM-like domain
COEPHNDF_01370 3e-90 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
COEPHNDF_01371 1.9e-232 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
COEPHNDF_01372 1.4e-175 lacX 5.1.3.3 G Aldose 1-epimerase
COEPHNDF_01374 1.1e-12
COEPHNDF_01376 3.6e-64
COEPHNDF_01377 7.8e-61 repB L Protein involved in initiation of plasmid replication
COEPHNDF_01378 3.4e-25
COEPHNDF_01379 2e-106 L Integrase
COEPHNDF_01380 8e-42 S RelB antitoxin
COEPHNDF_01381 1.6e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
COEPHNDF_01382 3.8e-58 MA20_25245 K acetyltransferase
COEPHNDF_01383 1.1e-40 S YoeB-like toxin of bacterial type II toxin-antitoxin system
COEPHNDF_01384 5.3e-43 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
COEPHNDF_01386 2.1e-49 E Zn peptidase
COEPHNDF_01387 1.4e-38 ps115 K Helix-turn-helix XRE-family like proteins
COEPHNDF_01388 6.3e-43
COEPHNDF_01389 9.2e-134 2.1.1.72 S Adenine-specific methyltransferase EcoRI
COEPHNDF_01390 6.3e-197 V Protein of unknown function DUF262
COEPHNDF_01391 4.2e-40 V ATPases associated with a variety of cellular activities
COEPHNDF_01392 9.5e-25 cspC K Probable zinc-ribbon domain
COEPHNDF_01395 6.9e-18
COEPHNDF_01396 1.6e-69 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
COEPHNDF_01397 3.5e-11
COEPHNDF_01398 1e-164 repB EP Plasmid replication protein
COEPHNDF_01399 1.6e-28
COEPHNDF_01400 2.6e-209 L Belongs to the 'phage' integrase family
COEPHNDF_01401 7.7e-165 2.1.1.72 L DNA methylAse
COEPHNDF_01402 6.2e-26 S response to antibiotic
COEPHNDF_01403 4e-41 S response to antibiotic
COEPHNDF_01404 2.1e-143 S response to antibiotic
COEPHNDF_01405 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
COEPHNDF_01406 2.5e-275 hsdM 2.1.1.72 V type I restriction-modification system
COEPHNDF_01407 4.2e-61 3.1.21.3 V Type I restriction modification DNA specificity domain
COEPHNDF_01408 3.6e-56 hsdS 3.1.21.3 L PFAM restriction modification system DNA specificity domain
COEPHNDF_01410 9.9e-233 S Domain of unknown function (DUF3883)
COEPHNDF_01411 1.6e-216 S SLAP domain
COEPHNDF_01412 2.4e-23 ykuL S IMP dehydrogenase activity
COEPHNDF_01413 6.1e-213 ywhK S Membrane
COEPHNDF_01414 3.8e-50
COEPHNDF_01415 5.2e-19 S D-Ala-teichoic acid biosynthesis protein
COEPHNDF_01416 1.6e-293 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COEPHNDF_01417 3e-242 dltB M MBOAT, membrane-bound O-acyltransferase family
COEPHNDF_01418 5.7e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COEPHNDF_01419 2.8e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
COEPHNDF_01420 1.6e-174 pbpX2 V Beta-lactamase
COEPHNDF_01422 2e-10
COEPHNDF_01423 1.1e-119 S CAAX protease self-immunity
COEPHNDF_01424 1.7e-29
COEPHNDF_01425 1.8e-32
COEPHNDF_01426 9.6e-16
COEPHNDF_01427 2.5e-121 S Protein of unknown function (DUF975)
COEPHNDF_01428 1.2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COEPHNDF_01429 8.2e-187 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
COEPHNDF_01430 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
COEPHNDF_01431 1.2e-188 lacR K Transcriptional regulator
COEPHNDF_01432 2.1e-24 lacS G Transporter
COEPHNDF_01433 1.4e-48 lacS G Transporter
COEPHNDF_01434 2.6e-108 lacS G Transporter
COEPHNDF_01435 0.0 lacS G Transporter
COEPHNDF_01436 3.8e-89 lacZ 3.2.1.23 G -beta-galactosidase
COEPHNDF_01437 2e-44 lacZ 3.2.1.23 G -beta-galactosidase
COEPHNDF_01438 9.4e-179 tcsA S ABC transporter substrate-binding protein PnrA-like
COEPHNDF_01439 2.3e-247 xylG 3.6.3.17 S ABC transporter
COEPHNDF_01440 1.7e-167 yufP S Belongs to the binding-protein-dependent transport system permease family
COEPHNDF_01441 2e-161 yufQ S Belongs to the binding-protein-dependent transport system permease family
COEPHNDF_01442 0.0 3.6.3.8 P P-type ATPase
COEPHNDF_01443 5.8e-212 clcA P chloride
COEPHNDF_01444 3.3e-39 XK27_08875 O Matrixin
COEPHNDF_01445 1.8e-46 S Domain of unknown function (DUF4160)
COEPHNDF_01446 1.9e-276 V ABC transporter transmembrane region
COEPHNDF_01447 9.3e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
COEPHNDF_01448 5.1e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
COEPHNDF_01449 3e-95 F Nucleoside 2-deoxyribosyltransferase
COEPHNDF_01450 2.7e-69 S Peptidase propeptide and YPEB domain
COEPHNDF_01451 5.8e-86 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
COEPHNDF_01452 1.4e-67 yybA 2.3.1.57 K Transcriptional regulator
COEPHNDF_01453 7.8e-14 S Peptidase propeptide and YPEB domain
COEPHNDF_01454 1.4e-66 S Peptidase propeptide and YPEB domain
COEPHNDF_01455 3.1e-245 G Bacterial extracellular solute-binding protein
COEPHNDF_01456 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COEPHNDF_01457 3.9e-170 coaA 2.7.1.33 F Pantothenic acid kinase
COEPHNDF_01458 1.1e-103 E GDSL-like Lipase/Acylhydrolase
COEPHNDF_01459 9.5e-92 S Bacterial membrane protein, YfhO
COEPHNDF_01460 1.6e-97
COEPHNDF_01461 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COEPHNDF_01462 3e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
COEPHNDF_01463 5.7e-126 S Haloacid dehalogenase-like hydrolase
COEPHNDF_01464 2.1e-114 radC L DNA repair protein
COEPHNDF_01465 4.2e-173 mreB D cell shape determining protein MreB
COEPHNDF_01466 6.7e-148 mreC M Involved in formation and maintenance of cell shape
COEPHNDF_01467 1.1e-95 mreD
COEPHNDF_01468 6.5e-13 S Protein of unknown function (DUF4044)
COEPHNDF_01469 2.2e-54 S Protein of unknown function (DUF3397)
COEPHNDF_01470 9.1e-77 mraZ K Belongs to the MraZ family
COEPHNDF_01471 3.3e-183 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COEPHNDF_01472 9.1e-54 ftsL D Cell division protein FtsL
COEPHNDF_01473 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
COEPHNDF_01474 7.1e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COEPHNDF_01475 4.3e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COEPHNDF_01476 8e-210 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COEPHNDF_01477 3.4e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
COEPHNDF_01478 5e-227 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
COEPHNDF_01479 1.6e-204 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COEPHNDF_01480 4.8e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COEPHNDF_01481 9e-47 yggT S YGGT family
COEPHNDF_01482 2.2e-148 ylmH S S4 domain protein
COEPHNDF_01483 3e-73 gpsB D DivIVA domain protein
COEPHNDF_01484 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COEPHNDF_01485 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
COEPHNDF_01486 4.4e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
COEPHNDF_01487 2.1e-38
COEPHNDF_01488 2.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COEPHNDF_01489 3.5e-216 iscS 2.8.1.7 E Aminotransferase class V
COEPHNDF_01490 4.1e-56 XK27_04120 S Putative amino acid metabolism
COEPHNDF_01491 6.7e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COEPHNDF_01492 7.3e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
COEPHNDF_01493 1e-79 S Repeat protein
COEPHNDF_01494 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COEPHNDF_01495 5.9e-106 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
COEPHNDF_01496 1.7e-27 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
COEPHNDF_01497 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COEPHNDF_01498 4.2e-33 ykzG S Belongs to the UPF0356 family
COEPHNDF_01499 1.7e-99 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COEPHNDF_01500 0.0 typA T GTP-binding protein TypA
COEPHNDF_01501 1.5e-206 ftsW D Belongs to the SEDS family
COEPHNDF_01502 8.7e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
COEPHNDF_01503 8.5e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
COEPHNDF_01504 2.7e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COEPHNDF_01505 1.4e-192 ylbL T Belongs to the peptidase S16 family
COEPHNDF_01506 3.1e-82 comEA L Competence protein ComEA
COEPHNDF_01507 0.0 comEC S Competence protein ComEC
COEPHNDF_01508 4.8e-174 holA 2.7.7.7 L DNA polymerase III delta subunit
COEPHNDF_01509 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
COEPHNDF_01510 7e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COEPHNDF_01511 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COEPHNDF_01512 2.4e-150
COEPHNDF_01513 4.7e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COEPHNDF_01514 1.5e-207 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COEPHNDF_01515 4.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COEPHNDF_01516 5.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
COEPHNDF_01517 2e-272 yjeM E Amino Acid
COEPHNDF_01518 9.2e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COEPHNDF_01519 1.9e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
COEPHNDF_01520 1.4e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COEPHNDF_01521 3.6e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
COEPHNDF_01522 4e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
COEPHNDF_01523 2.7e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COEPHNDF_01524 8.6e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COEPHNDF_01525 1.8e-212 aspC 2.6.1.1 E Aminotransferase
COEPHNDF_01526 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COEPHNDF_01527 9.1e-206 pbpX1 V Beta-lactamase
COEPHNDF_01528 5.3e-110 3.6.1.55 F NUDIX domain
COEPHNDF_01529 3.2e-300 I Protein of unknown function (DUF2974)
COEPHNDF_01530 8.3e-36 C FMN_bind
COEPHNDF_01531 4.3e-10
COEPHNDF_01532 6.1e-55
COEPHNDF_01533 1e-173 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
COEPHNDF_01534 3.9e-170 S Aldo keto reductase
COEPHNDF_01535 8.6e-289 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COEPHNDF_01536 8.6e-116 K UTRA domain
COEPHNDF_01538 8.8e-144 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
COEPHNDF_01539 1.2e-54 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
COEPHNDF_01540 7.5e-108 pncA Q Isochorismatase family
COEPHNDF_01541 1.1e-267 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COEPHNDF_01542 5.4e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
COEPHNDF_01544 2.1e-72 S Iron-sulphur cluster biosynthesis
COEPHNDF_01545 8.6e-119 S CAAX protease self-immunity
COEPHNDF_01546 5.6e-195 S DUF218 domain
COEPHNDF_01547 0.0 macB_3 V ABC transporter, ATP-binding protein
COEPHNDF_01548 2.9e-97 S ECF transporter, substrate-specific component
COEPHNDF_01549 6.3e-159 yeaE S Aldo/keto reductase family
COEPHNDF_01550 1.4e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COEPHNDF_01551 6.1e-101 ybbH_2 K rpiR family
COEPHNDF_01552 1e-145 S Bacterial protein of unknown function (DUF871)
COEPHNDF_01553 3.9e-76 yfeW 3.4.16.4 V Beta-lactamase
COEPHNDF_01554 8.7e-131 ybbM S Uncharacterised protein family (UPF0014)
COEPHNDF_01555 5.8e-112 ybbL S ABC transporter, ATP-binding protein
COEPHNDF_01556 3.9e-30 WQ51_00220 K Helix-turn-helix XRE-family like proteins
COEPHNDF_01558 2.4e-154 V ABC transporter transmembrane region
COEPHNDF_01560 2.6e-244 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COEPHNDF_01561 9.1e-295 3.1.21.5 L Type III restriction enzyme, res subunit
COEPHNDF_01562 8.7e-26 2.1.1.72 L DNA methylAse
COEPHNDF_01563 5e-23 repA S Replication initiator protein A
COEPHNDF_01564 6.9e-213 mdtG EGP Major facilitator Superfamily
COEPHNDF_01565 5.7e-167
COEPHNDF_01566 1.2e-58 lysM M LysM domain
COEPHNDF_01568 0.0 pepN 3.4.11.2 E aminopeptidase
COEPHNDF_01569 1e-247 dtpT U amino acid peptide transporter
COEPHNDF_01570 1.8e-24
COEPHNDF_01571 1.6e-182 S Putative peptidoglycan binding domain
COEPHNDF_01572 0.0 FbpA K Fibronectin-binding protein
COEPHNDF_01573 7.7e-65
COEPHNDF_01574 1.8e-159 degV S EDD domain protein, DegV family
COEPHNDF_01575 7.6e-205 xerS L Belongs to the 'phage' integrase family
COEPHNDF_01576 5.3e-67
COEPHNDF_01577 5.9e-88 adk 2.7.4.3 F topology modulation protein
COEPHNDF_01578 4.4e-109 XK27_00160 S Domain of unknown function (DUF5052)
COEPHNDF_01579 1.3e-52
COEPHNDF_01580 8.2e-28 M Glycosyl hydrolases family 25
COEPHNDF_01581 3.4e-92 M Glycosyl hydrolases family 25
COEPHNDF_01582 3.3e-24 lysA2 M Glycosyl hydrolases family 25
COEPHNDF_01583 3.5e-36 S Transglycosylase associated protein
COEPHNDF_01584 1.6e-67
COEPHNDF_01585 1.4e-33
COEPHNDF_01586 4e-11 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COEPHNDF_01587 1.2e-74 nrdI F Belongs to the NrdI family
COEPHNDF_01588 2.8e-95
COEPHNDF_01589 3.8e-279 S O-antigen ligase like membrane protein
COEPHNDF_01590 4.3e-25
COEPHNDF_01591 2.7e-94 gmk2 2.7.4.8 F Guanylate kinase homologues.
COEPHNDF_01592 6.2e-94 M NlpC/P60 family
COEPHNDF_01593 9e-30 S Archaea bacterial proteins of unknown function
COEPHNDF_01594 3.6e-59 S Archaea bacterial proteins of unknown function
COEPHNDF_01595 1e-105 L Resolvase, N terminal domain
COEPHNDF_01596 1.4e-256 L Probable transposase
COEPHNDF_01597 8e-124 M NlpC P60 family protein
COEPHNDF_01608 8.1e-221 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
COEPHNDF_01609 4.2e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
COEPHNDF_01610 3.3e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COEPHNDF_01611 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COEPHNDF_01612 2.3e-29 secG U Preprotein translocase
COEPHNDF_01613 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COEPHNDF_01614 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COEPHNDF_01615 4.3e-209 E IrrE N-terminal-like domain
COEPHNDF_01616 5.6e-08 yfdK S phosphatase homologous to the C-terminal domain of histone macroH2A1
COEPHNDF_01617 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
COEPHNDF_01618 1.7e-53 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COEPHNDF_01619 4.1e-141 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COEPHNDF_01620 9.2e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COEPHNDF_01621 6.2e-96 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
COEPHNDF_01622 1.2e-26
COEPHNDF_01623 4.4e-84
COEPHNDF_01624 0.0 O Belongs to the peptidase S8 family
COEPHNDF_01625 5.3e-40 3.6.4.12 L DnaB-like helicase C terminal domain
COEPHNDF_01626 2.5e-77 L Transposase DDE domain
COEPHNDF_01627 2e-20 S Domain of unknown function (DUF4298)
COEPHNDF_01628 1.7e-114 papP P ABC transporter, permease protein
COEPHNDF_01629 4.8e-117 P ABC transporter permease
COEPHNDF_01630 8.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COEPHNDF_01631 1.7e-162 cjaA ET ABC transporter substrate-binding protein
COEPHNDF_01632 3.3e-52 S Iron-sulfur cluster assembly protein
COEPHNDF_01633 9.5e-43 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
COEPHNDF_01634 9.4e-91 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
COEPHNDF_01635 4.3e-35 sdaAB 4.3.1.17 E Serine dehydratase beta chain
COEPHNDF_01636 2.3e-07 sdaAB 4.3.1.17 E Serine dehydratase beta chain
COEPHNDF_01637 9.7e-46
COEPHNDF_01639 9.9e-97 S Cysteine-rich secretory protein family
COEPHNDF_01640 4.3e-49
COEPHNDF_01641 4.6e-206 G Major Facilitator Superfamily
COEPHNDF_01642 1.5e-51
COEPHNDF_01643 1.2e-80 S Threonine/Serine exporter, ThrE
COEPHNDF_01644 4.4e-138 thrE S Putative threonine/serine exporter
COEPHNDF_01645 1.7e-290 S ABC transporter
COEPHNDF_01646 1e-55
COEPHNDF_01647 1.2e-85 rimL J Acetyltransferase (GNAT) domain
COEPHNDF_01648 5.5e-116 S Protein of unknown function (DUF554)
COEPHNDF_01649 5.4e-215 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COEPHNDF_01650 0.0 pepF E oligoendopeptidase F
COEPHNDF_01651 1.6e-41 Z012_06740 S Fic/DOC family
COEPHNDF_01652 4.6e-280 arlS 2.7.13.3 T Histidine kinase
COEPHNDF_01653 3.2e-127 K response regulator
COEPHNDF_01654 1e-96 yceD S Uncharacterized ACR, COG1399
COEPHNDF_01655 6.6e-215 ylbM S Belongs to the UPF0348 family
COEPHNDF_01656 6.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COEPHNDF_01657 2.3e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
COEPHNDF_01658 2.4e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COEPHNDF_01659 1.6e-210 yqeH S Ribosome biogenesis GTPase YqeH
COEPHNDF_01660 3.8e-93 yqeG S HAD phosphatase, family IIIA
COEPHNDF_01661 5.1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COEPHNDF_01662 1.8e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
COEPHNDF_01663 1.8e-54 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COEPHNDF_01664 8.9e-37 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
COEPHNDF_01665 3.5e-157 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
COEPHNDF_01666 9.3e-30 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
COEPHNDF_01667 2.9e-184 S Domain of unknown function (DUF389)
COEPHNDF_01668 4.1e-95
COEPHNDF_01669 1.5e-89
COEPHNDF_01670 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COEPHNDF_01671 1.7e-165 dnaI L Primosomal protein DnaI
COEPHNDF_01672 4.4e-247 dnaB L Replication initiation and membrane attachment
COEPHNDF_01673 4.1e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COEPHNDF_01674 1.4e-104 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COEPHNDF_01675 1.3e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COEPHNDF_01676 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COEPHNDF_01677 9e-14
COEPHNDF_01678 1.4e-28 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COEPHNDF_01679 2.9e-198 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COEPHNDF_01680 1e-124 cas4 3.1.12.1 L Domain of unknown function DUF83
COEPHNDF_01681 9.3e-158 csd2 L CRISPR-associated protein Cas7
COEPHNDF_01682 0.0 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
COEPHNDF_01683 4.1e-141 cas5d S CRISPR-associated protein (Cas_Cas5)
COEPHNDF_01684 0.0 cas3 L Type III restriction enzyme, res subunit
COEPHNDF_01685 7.1e-239 purD 6.3.4.13 F Belongs to the GARS family
COEPHNDF_01686 3.2e-289 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
COEPHNDF_01687 3.2e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COEPHNDF_01688 1.2e-194 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
COEPHNDF_01689 1.5e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COEPHNDF_01690 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COEPHNDF_01691 2.3e-119 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COEPHNDF_01692 1.9e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COEPHNDF_01693 3.9e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
COEPHNDF_01694 1.1e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COEPHNDF_01695 4.2e-78 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COEPHNDF_01696 1.3e-309 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
COEPHNDF_01697 7.5e-123 darA C Flavodoxin
COEPHNDF_01698 4.8e-141 qmcA O prohibitin homologues
COEPHNDF_01699 4.3e-52 L RelB antitoxin
COEPHNDF_01700 3.8e-20
COEPHNDF_01701 2.9e-195 S Bacteriocin helveticin-J
COEPHNDF_01702 7.9e-39 M Peptidase family M1 domain
COEPHNDF_01703 3.6e-142 M Peptidase family M1 domain
COEPHNDF_01704 7e-62 M Peptidase family M1 domain
COEPHNDF_01705 8.7e-176 S SLAP domain
COEPHNDF_01706 9.7e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
COEPHNDF_01707 0.0 S SLAP domain
COEPHNDF_01708 3.3e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COEPHNDF_01709 7.3e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
COEPHNDF_01710 1e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COEPHNDF_01711 1.7e-213 ecsB U ABC transporter
COEPHNDF_01712 3.9e-136 ecsA V ABC transporter, ATP-binding protein
COEPHNDF_01713 3.8e-54 higA K Helix-turn-helix XRE-family like proteins
COEPHNDF_01714 3.4e-79 hit FG Scavenger mRNA decapping enzyme C-term binding
COEPHNDF_01715 8e-28
COEPHNDF_01716 1.3e-154 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COEPHNDF_01717 8.4e-21
COEPHNDF_01718 1.8e-93
COEPHNDF_01719 8.1e-22 S Small integral membrane protein (DUF2273)
COEPHNDF_01720 1.5e-84 S Asp23 family, cell envelope-related function
COEPHNDF_01721 1.3e-11 S Transglycosylase associated protein
COEPHNDF_01722 1.3e-16
COEPHNDF_01723 2.6e-45 IQ Enoyl-(Acyl carrier protein) reductase
COEPHNDF_01724 3.5e-55 L Transposase and inactivated derivatives, IS30 family
COEPHNDF_01725 3.5e-152 asdA 4.1.1.12 E Aminotransferase
COEPHNDF_01726 5.2e-245 aspT P Predicted Permease Membrane Region
COEPHNDF_01727 1.1e-84 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
COEPHNDF_01728 0.0 cadA P P-type ATPase
COEPHNDF_01729 1.3e-202 napA P Sodium/hydrogen exchanger family
COEPHNDF_01730 1.5e-49 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
COEPHNDF_01731 3.6e-47 S YoeB-like toxin of bacterial type II toxin-antitoxin system
COEPHNDF_01732 1.1e-144 V ABC transporter transmembrane region
COEPHNDF_01733 5.1e-76 S Putative adhesin
COEPHNDF_01734 1.5e-155 mutR K Helix-turn-helix XRE-family like proteins
COEPHNDF_01735 1.6e-45
COEPHNDF_01736 7.5e-71 L Transposase
COEPHNDF_01737 3.2e-41 L PFAM transposase, IS4 family protein
COEPHNDF_01738 1.3e-84 L PFAM transposase, IS4 family protein
COEPHNDF_01739 3.2e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
COEPHNDF_01740 1.2e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
COEPHNDF_01741 1.4e-167 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COEPHNDF_01742 6.6e-290 V ABC-type multidrug transport system, ATPase and permease components
COEPHNDF_01743 7.5e-286 V ABC-type multidrug transport system, ATPase and permease components
COEPHNDF_01745 5.7e-16 L PFAM IS66 Orf2 family protein
COEPHNDF_01746 1.2e-08
COEPHNDF_01747 3.3e-14 S Phage derived protein Gp49-like (DUF891)
COEPHNDF_01748 1.5e-40 K Helix-turn-helix XRE-family like proteins
COEPHNDF_01749 5.3e-43
COEPHNDF_01750 2.8e-21 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COEPHNDF_01751 7.6e-65 L Probable transposase
COEPHNDF_01752 1e-162 L Probable transposase
COEPHNDF_01753 2.5e-14 S Fic/DOC family
COEPHNDF_01754 7.9e-52
COEPHNDF_01755 8e-79 K Acetyltransferase (GNAT) domain
COEPHNDF_01757 1.6e-51 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
COEPHNDF_01758 8.7e-131 2.4.2.3 F Phosphorylase superfamily
COEPHNDF_01759 2.1e-119 XK27_07525 3.6.1.55 F NUDIX domain
COEPHNDF_01760 7.9e-81 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
COEPHNDF_01761 9.3e-64 5.4.2.11 G Phosphoglycerate mutase family
COEPHNDF_01762 2e-80 S AAA domain
COEPHNDF_01763 1.1e-41 S MazG-like family
COEPHNDF_01764 4.5e-264 lsa S ABC transporter
COEPHNDF_01765 3.4e-252 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COEPHNDF_01766 2.3e-96 J Acetyltransferase (GNAT) domain
COEPHNDF_01767 2.8e-108 yjbF S SNARE associated Golgi protein
COEPHNDF_01768 1.3e-153 I alpha/beta hydrolase fold
COEPHNDF_01769 5.9e-126 hipB K Helix-turn-helix
COEPHNDF_01770 2.5e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
COEPHNDF_01771 4.3e-149
COEPHNDF_01772 2.9e-254 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
COEPHNDF_01774 6.1e-72 3.1.21.3 V Type I restriction modification DNA specificity domain
COEPHNDF_01775 9.5e-92 L Helix-turn-helix domain
COEPHNDF_01776 1.7e-102 L HTH-like domain
COEPHNDF_01777 0.0 uvrA2 L ABC transporter
COEPHNDF_01778 2.1e-42 S Enterocin A Immunity
COEPHNDF_01779 3.6e-52 lctP C L-lactate permease
COEPHNDF_01780 3.6e-90 lctP C L-lactate permease
COEPHNDF_01781 5.2e-24 lctP C L-lactate permease
COEPHNDF_01782 9.9e-234 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COEPHNDF_01783 2.6e-130 znuB U ABC 3 transport family
COEPHNDF_01784 7.9e-117 fhuC P ABC transporter
COEPHNDF_01785 4.4e-158 psaA P Belongs to the bacterial solute-binding protein 9 family
COEPHNDF_01786 1e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
COEPHNDF_01787 3.4e-73 metQ_4 P Belongs to the nlpA lipoprotein family
COEPHNDF_01788 1.4e-84 IQ reductase
COEPHNDF_01789 4.7e-193 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COEPHNDF_01790 1.2e-73 nrdI F Probably involved in ribonucleotide reductase function
COEPHNDF_01791 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COEPHNDF_01792 7.3e-40 S Enterocin A Immunity
COEPHNDF_01793 4.6e-118 ropB K Transcriptional regulator
COEPHNDF_01794 1.6e-20
COEPHNDF_01795 7.2e-172 yfdH GT2 M Glycosyltransferase like family 2
COEPHNDF_01796 2.4e-66 2.4.1.83 GT2 S GtrA-like protein
COEPHNDF_01797 3.4e-213 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
COEPHNDF_01798 6.7e-23
COEPHNDF_01799 3.3e-19 S SLAP domain
COEPHNDF_01801 0.0 1.3.5.4 C FAD binding domain
COEPHNDF_01805 2.8e-98 D Alpha beta
COEPHNDF_01806 3.3e-261 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COEPHNDF_01807 9.6e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
COEPHNDF_01808 1.9e-86
COEPHNDF_01809 1.3e-73
COEPHNDF_01810 1.3e-159 hlyX S Transporter associated domain
COEPHNDF_01811 3.2e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COEPHNDF_01812 3.9e-44 XK27_09445 S Domain of unknown function (DUF1827)
COEPHNDF_01813 0.0 clpE O Belongs to the ClpA ClpB family
COEPHNDF_01814 2.4e-26
COEPHNDF_01815 8.5e-41 ptsH G phosphocarrier protein HPR
COEPHNDF_01816 1.9e-306 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COEPHNDF_01817 7.9e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COEPHNDF_01818 2.6e-132 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
COEPHNDF_01819 1.5e-158 coiA 3.6.4.12 S Competence protein
COEPHNDF_01820 2.8e-111 yjbH Q Thioredoxin
COEPHNDF_01821 1.1e-112 yjbK S CYTH
COEPHNDF_01822 2.3e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
COEPHNDF_01823 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COEPHNDF_01824 5e-170 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COEPHNDF_01825 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
COEPHNDF_01826 1.3e-29 S SNARE associated Golgi protein
COEPHNDF_01827 3.7e-37 S SNARE associated Golgi protein
COEPHNDF_01828 5.7e-202 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
COEPHNDF_01829 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
COEPHNDF_01830 2.4e-65 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
COEPHNDF_01831 9.3e-212 yubA S AI-2E family transporter
COEPHNDF_01832 1.6e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COEPHNDF_01833 1.4e-68 WQ51_03320 S Protein of unknown function (DUF1149)
COEPHNDF_01834 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
COEPHNDF_01835 8.7e-226 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
COEPHNDF_01836 1.3e-235 S Peptidase M16
COEPHNDF_01837 5.2e-133 IQ Enoyl-(Acyl carrier protein) reductase
COEPHNDF_01838 4e-129 ymfM S Helix-turn-helix domain
COEPHNDF_01839 2.1e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COEPHNDF_01840 3.6e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COEPHNDF_01841 4.7e-219 rny S Endoribonuclease that initiates mRNA decay
COEPHNDF_01842 2.4e-209 tagO 2.7.8.33, 2.7.8.35 M transferase
COEPHNDF_01843 2.4e-116 yvyE 3.4.13.9 S YigZ family
COEPHNDF_01844 4.7e-246 comFA L Helicase C-terminal domain protein
COEPHNDF_01845 5.9e-134 comFC S Competence protein
COEPHNDF_01846 9.4e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COEPHNDF_01847 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COEPHNDF_01848 3.3e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COEPHNDF_01849 8.4e-23
COEPHNDF_01850 3.7e-179 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COEPHNDF_01851 9.8e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COEPHNDF_01852 3e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
COEPHNDF_01853 2.7e-183 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
COEPHNDF_01854 5.9e-56 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
COEPHNDF_01855 2.4e-63 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
COEPHNDF_01856 9.8e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
COEPHNDF_01857 5e-229 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
COEPHNDF_01858 3.2e-61 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
COEPHNDF_01859 1.1e-63 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
COEPHNDF_01860 4.8e-127 L Transposase DDE domain
COEPHNDF_01861 2e-41 K LysR substrate binding domain
COEPHNDF_01862 1.4e-100 K LysR substrate binding domain
COEPHNDF_01863 3.8e-108 K Transcriptional regulator, LysR family
COEPHNDF_01864 1.3e-34 S Cytochrome b5
COEPHNDF_01865 1.6e-165 arbZ I Phosphate acyltransferases
COEPHNDF_01866 5.3e-162 arbY M Glycosyl transferase family 8
COEPHNDF_01867 1.7e-184 arbY M Glycosyl transferase family 8
COEPHNDF_01868 1.7e-143 arbx M Glycosyl transferase family 8
COEPHNDF_01869 3.6e-129 arbV 2.3.1.51 I Acyl-transferase
COEPHNDF_01871 1.5e-19 pfoS S Phosphotransferase system, EIIC
COEPHNDF_01872 1.3e-114 pfoS S Phosphotransferase system, EIIC
COEPHNDF_01873 2.5e-35 slpX S SLAP domain
COEPHNDF_01874 1.3e-213 slpX S SLAP domain
COEPHNDF_01875 1.5e-92
COEPHNDF_01878 7.8e-213
COEPHNDF_01879 1.6e-123 gntR1 K UTRA
COEPHNDF_01880 1.8e-55 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
COEPHNDF_01881 9.7e-86
COEPHNDF_01882 3.9e-44 relB L Addiction module antitoxin, RelB DinJ family
COEPHNDF_01883 5.2e-50 repA S Replication initiator protein A
COEPHNDF_01884 3.2e-71 repA S Replication initiator protein A
COEPHNDF_01885 1.8e-75 sdrF M domain protein
COEPHNDF_01886 3.4e-98 infB M YSIRK type signal peptide
COEPHNDF_01887 4.5e-16 sdrF M domain protein
COEPHNDF_01888 8.4e-139 pnuC H nicotinamide mononucleotide transporter
COEPHNDF_01889 4.1e-11
COEPHNDF_01890 4.2e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
COEPHNDF_01891 1.7e-146 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
COEPHNDF_01892 8.2e-54 S Iron-sulfur cluster assembly protein
COEPHNDF_01894 1.1e-12 M NlpC/P60 family
COEPHNDF_01895 1.1e-22 M NlpC/P60 family
COEPHNDF_01896 4.7e-66 M NlpC/P60 family
COEPHNDF_01897 7.9e-114 G Peptidase_C39 like family
COEPHNDF_01898 3e-26
COEPHNDF_01900 3.2e-30
COEPHNDF_01902 1.9e-124 XK27_06785 V ABC transporter, ATP-binding protein
COEPHNDF_01903 2.3e-113 XK27_06780 V ABC transporter permease
COEPHNDF_01904 6.1e-193 XK27_06780 V ABC transporter permease
COEPHNDF_01905 1.2e-35
COEPHNDF_01906 4.5e-286 ytgP S Polysaccharide biosynthesis protein
COEPHNDF_01907 3.8e-147 lysA2 M Glycosyl hydrolases family 25
COEPHNDF_01908 2.8e-101 yfeW 3.4.16.4 V Beta-lactamase
COEPHNDF_01909 4.3e-121 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
COEPHNDF_01910 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
COEPHNDF_01912 2.7e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
COEPHNDF_01913 1.8e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
COEPHNDF_01914 6.8e-153 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
COEPHNDF_01915 6.6e-218 yceI EGP Major facilitator Superfamily
COEPHNDF_01916 3.8e-70 L Transposase and inactivated derivatives, IS30 family
COEPHNDF_01917 3.2e-223 oxlT P Major Facilitator Superfamily
COEPHNDF_01918 4.8e-89 L transposase, IS605 OrfB family
COEPHNDF_01919 1.1e-44 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
COEPHNDF_01920 2.3e-118 S Membrane
COEPHNDF_01921 2.3e-107 S Domain of unknown function (DUF4767)
COEPHNDF_01928 7.7e-78
COEPHNDF_01929 1.1e-272 pepV 3.5.1.18 E dipeptidase PepV
COEPHNDF_01930 5.3e-189 V Beta-lactamase
COEPHNDF_01931 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
COEPHNDF_01932 9.6e-47
COEPHNDF_01933 7.4e-138
COEPHNDF_01934 4.6e-88 XK27_09675 K Acetyltransferase (GNAT) domain
COEPHNDF_01935 3e-53 S Protein of unknown function (DUF3021)
COEPHNDF_01936 1.6e-76 K LytTr DNA-binding domain
COEPHNDF_01937 1e-41
COEPHNDF_01938 8e-125 magIII L Base excision DNA repair protein, HhH-GPD family
COEPHNDF_01939 2e-22 K Helix-turn-helix XRE-family like proteins
COEPHNDF_01940 2.4e-51
COEPHNDF_01941 8.9e-140 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
COEPHNDF_01942 8.8e-229 yrvN L AAA C-terminal domain
COEPHNDF_01943 2.1e-32
COEPHNDF_01944 9.1e-71 fabK 1.3.1.9 S Nitronate monooxygenase
COEPHNDF_01945 1.5e-84 kptA H Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
COEPHNDF_01946 8.5e-66 S Abi-like protein
COEPHNDF_01948 1.3e-125 4.1.1.45 S Amidohydrolase
COEPHNDF_01949 2e-93 lacA 2.3.1.79 S Maltose acetyltransferase
COEPHNDF_01950 1.4e-81 G Antibiotic biosynthesis monooxygenase
COEPHNDF_01951 1.4e-19 G Antibiotic biosynthesis monooxygenase
COEPHNDF_01952 2.8e-27 S Uncharacterized protein conserved in bacteria (DUF2255)
COEPHNDF_01953 1e-69 adhR K helix_turn_helix, mercury resistance
COEPHNDF_01954 6e-112 papP P ABC transporter, permease protein
COEPHNDF_01955 3.1e-87 P ABC transporter permease
COEPHNDF_01956 5.3e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COEPHNDF_01957 1.7e-159 cjaA ET ABC transporter substrate-binding protein
COEPHNDF_01958 9.5e-124 L Helix-turn-helix domain
COEPHNDF_01959 2.2e-123 L hmm pf00665
COEPHNDF_01961 9.9e-117 L Integrase
COEPHNDF_01963 8.4e-254 gor 1.8.1.7 C Glutathione reductase
COEPHNDF_01964 1.9e-92 K Acetyltransferase (GNAT) family
COEPHNDF_01965 1.4e-57 S Alpha beta hydrolase
COEPHNDF_01966 1.5e-59 S Hydrolases of the alpha beta superfamily
COEPHNDF_01967 1.4e-141 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
COEPHNDF_01968 7.8e-46 1.1.1.3 T phosphoserine phosphatase activity
COEPHNDF_01969 7.3e-83 K Bacterial regulatory proteins, tetR family
COEPHNDF_01970 1.6e-108 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COEPHNDF_01971 1.5e-39 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COEPHNDF_01972 1.8e-49 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COEPHNDF_01973 1.1e-71 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
COEPHNDF_01974 5.3e-79 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
COEPHNDF_01975 4.4e-94 K acetyltransferase
COEPHNDF_01976 5.8e-85 dps P Belongs to the Dps family
COEPHNDF_01977 9.1e-18
COEPHNDF_01978 7.8e-32
COEPHNDF_01979 7.1e-18 snf 2.7.11.1 KL domain protein
COEPHNDF_01980 3.9e-43 snf 2.7.11.1 KL domain protein
COEPHNDF_01981 1.8e-288 snf 2.7.11.1 KL domain protein
COEPHNDF_01982 1.4e-102 snf 2.7.11.1 KL domain protein
COEPHNDF_01983 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COEPHNDF_01984 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COEPHNDF_01985 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COEPHNDF_01986 3.8e-171 K Transcriptional regulator
COEPHNDF_01987 3.3e-164 ppaC 3.6.1.1 C inorganic pyrophosphatase
COEPHNDF_01988 5.9e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COEPHNDF_01989 6.2e-55 K Helix-turn-helix domain
COEPHNDF_01990 7e-23 yoaK S Protein of unknown function (DUF1275)
COEPHNDF_01991 6.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COEPHNDF_01992 5.2e-281 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COEPHNDF_01993 5.9e-205 csaB M Glycosyl transferases group 1
COEPHNDF_01994 5.6e-135 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
COEPHNDF_01995 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COEPHNDF_01996 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
COEPHNDF_01997 3.8e-276 E Amino acid permease
COEPHNDF_01998 1.9e-85 L transposase, IS605 OrfB family
COEPHNDF_01999 4.6e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
COEPHNDF_02000 3.3e-217 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
COEPHNDF_02001 6e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
COEPHNDF_02002 4.2e-46
COEPHNDF_02003 7.7e-19 D Alpha beta
COEPHNDF_02004 2.8e-76 L COG2826 Transposase and inactivated derivatives, IS30 family
COEPHNDF_02005 2e-13
COEPHNDF_02006 1.1e-57
COEPHNDF_02007 2.3e-07
COEPHNDF_02009 1.2e-115 S SLAP domain
COEPHNDF_02010 3.1e-45 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
COEPHNDF_02011 3.6e-45 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
COEPHNDF_02012 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
COEPHNDF_02013 4.3e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COEPHNDF_02014 8.7e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COEPHNDF_02015 2.9e-120 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
COEPHNDF_02016 1.3e-165 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COEPHNDF_02017 1.1e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COEPHNDF_02018 3.4e-68 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
COEPHNDF_02019 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COEPHNDF_02020 8.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COEPHNDF_02021 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COEPHNDF_02022 2.3e-122 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
COEPHNDF_02023 0.0 helD 3.6.4.12 L DNA helicase
COEPHNDF_02024 1.7e-125 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
COEPHNDF_02025 5.5e-126 pgm3 G Phosphoglycerate mutase family
COEPHNDF_02027 3.2e-119 yhiD S MgtC family
COEPHNDF_02028 7.5e-241 I Protein of unknown function (DUF2974)
COEPHNDF_02029 4.7e-36
COEPHNDF_02031 7.9e-76 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COEPHNDF_02032 1.4e-37 L Transposase and inactivated derivatives
COEPHNDF_02033 9.6e-155 L Integrase core domain
COEPHNDF_02034 3.2e-69 S Membrane transport protein
COEPHNDF_02035 9.3e-149 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEPHNDF_02036 5.5e-97 yxkA S Phosphatidylethanolamine-binding protein
COEPHNDF_02037 3.1e-248 yjjP S Putative threonine/serine exporter
COEPHNDF_02038 4e-173 citR K Putative sugar-binding domain
COEPHNDF_02039 2.7e-51
COEPHNDF_02040 4.7e-16
COEPHNDF_02041 2.2e-66 S Domain of unknown function DUF1828
COEPHNDF_02042 1.4e-93 S UPF0397 protein
COEPHNDF_02043 0.0 ykoD P ABC transporter, ATP-binding protein
COEPHNDF_02044 4.7e-129 cbiQ P cobalt transport
COEPHNDF_02045 1e-09
COEPHNDF_02046 5.3e-48 yeaL S Protein of unknown function (DUF441)
COEPHNDF_02047 8.4e-77 M1-431 S Protein of unknown function (DUF1706)
COEPHNDF_02048 2.8e-91
COEPHNDF_02049 2.4e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
COEPHNDF_02050 8.2e-168 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
COEPHNDF_02051 3.4e-43 citD C Covalent carrier of the coenzyme of citrate lyase
COEPHNDF_02052 7.4e-197 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
COEPHNDF_02053 1.3e-153 ydjP I Alpha/beta hydrolase family
COEPHNDF_02054 4.4e-272 P Sodium:sulfate symporter transmembrane region
COEPHNDF_02055 1.9e-258 pepC 3.4.22.40 E Peptidase C1-like family
COEPHNDF_02056 1.3e-47
COEPHNDF_02057 2.1e-43
COEPHNDF_02058 6.4e-74 fhaB M Rib/alpha-like repeat
COEPHNDF_02059 1.1e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COEPHNDF_02061 2.1e-16 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
COEPHNDF_02062 2.8e-19 UW LPXTG-motif cell wall anchor domain protein
COEPHNDF_02063 1.6e-263 frdC 1.3.5.4 C FAD binding domain
COEPHNDF_02064 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COEPHNDF_02065 1.7e-34
COEPHNDF_02066 1.9e-188 S cog cog1373
COEPHNDF_02067 8.4e-88 metI P ABC transporter permease
COEPHNDF_02068 1.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COEPHNDF_02069 2.2e-162 metQ1 P Belongs to the nlpA lipoprotein family
COEPHNDF_02070 0.0 aha1 P E1-E2 ATPase
COEPHNDF_02071 7.2e-16 ps301 K sequence-specific DNA binding
COEPHNDF_02072 2.4e-95 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COEPHNDF_02073 5.7e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COEPHNDF_02074 2.7e-247 yifK E Amino acid permease
COEPHNDF_02075 5e-57 S PFAM Uncharacterised protein family UPF0150
COEPHNDF_02077 1e-123 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COEPHNDF_02078 2.5e-31 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COEPHNDF_02079 2.3e-99 3.6.1.27 I Acid phosphatase homologues
COEPHNDF_02080 6.6e-132 yitS S Uncharacterised protein, DegV family COG1307
COEPHNDF_02081 1.2e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COEPHNDF_02082 1.6e-66 S Domain of unknown function (DUF4767)
COEPHNDF_02083 1.9e-56 C nitroreductase
COEPHNDF_02084 6.1e-149 ypbG 2.7.1.2 GK ROK family
COEPHNDF_02085 3.2e-277 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COEPHNDF_02086 9.4e-135 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COEPHNDF_02087 1.1e-144 cof S haloacid dehalogenase-like hydrolase
COEPHNDF_02088 4.8e-230 pbuG S permease
COEPHNDF_02089 8.5e-174 S cog cog1373
COEPHNDF_02090 7.2e-36 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
COEPHNDF_02091 1.4e-11 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COEPHNDF_02092 3.2e-148 ydiM G Major facilitator superfamily
COEPHNDF_02094 6.1e-72 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COEPHNDF_02095 6.6e-75 K LytTr DNA-binding domain
COEPHNDF_02096 1.9e-74 S Protein of unknown function (DUF3021)
COEPHNDF_02097 2.8e-147 V ABC transporter
COEPHNDF_02098 5.2e-91 S domain protein
COEPHNDF_02099 4.4e-08 ropB K Transcriptional regulator
COEPHNDF_02100 1e-208 EGP Major facilitator Superfamily
COEPHNDF_02101 5.2e-116 ropB K Transcriptional regulator
COEPHNDF_02102 1.5e-29
COEPHNDF_02103 1.3e-44
COEPHNDF_02104 6.8e-78 S Domain of unknown function (DUF5067)
COEPHNDF_02105 4.8e-63
COEPHNDF_02106 1.5e-48
COEPHNDF_02107 2.6e-143 2.4.2.3 F Phosphorylase superfamily
COEPHNDF_02110 3.9e-193 M Glycosyl transferase family group 2
COEPHNDF_02112 4.7e-85 K helix_turn_helix, mercury resistance
COEPHNDF_02113 7.5e-25 K helix_turn_helix, mercury resistance
COEPHNDF_02114 8.2e-230 pbuG S permease
COEPHNDF_02115 0.0 N Uncharacterized conserved protein (DUF2075)
COEPHNDF_02116 2.6e-291 K Putative DNA-binding domain
COEPHNDF_02117 1.5e-95 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
COEPHNDF_02118 2.8e-183 P secondary active sulfate transmembrane transporter activity

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)