ORF_ID e_value Gene_name EC_number CAZy COGs Description
HFHCACOH_00001 6e-200 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFHCACOH_00002 0.0 dnaK O Heat shock 70 kDa protein
HFHCACOH_00003 1e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFHCACOH_00004 2.2e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFHCACOH_00005 8.9e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HFHCACOH_00006 1.3e-165 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFHCACOH_00007 3.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFHCACOH_00008 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFHCACOH_00009 1e-45 rplGA J ribosomal protein
HFHCACOH_00010 1.5e-46 ylxR K Protein of unknown function (DUF448)
HFHCACOH_00011 6.6e-194 nusA K Participates in both transcription termination and antitermination
HFHCACOH_00012 5.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HFHCACOH_00013 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFHCACOH_00014 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFHCACOH_00015 2.6e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HFHCACOH_00016 3e-145 cdsA 2.7.7.41 I Belongs to the CDS family
HFHCACOH_00017 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFHCACOH_00018 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFHCACOH_00019 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HFHCACOH_00020 1.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFHCACOH_00021 1.2e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
HFHCACOH_00022 2.3e-198 yabB 2.1.1.223 L Methyltransferase small domain
HFHCACOH_00023 5.1e-113 plsC 2.3.1.51 I Acyltransferase
HFHCACOH_00024 2.9e-226 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HFHCACOH_00025 0.0 pepO 3.4.24.71 O Peptidase family M13
HFHCACOH_00026 1.2e-300 mdlB V ABC transporter
HFHCACOH_00027 1.4e-296 mdlA V ABC transporter
HFHCACOH_00028 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
HFHCACOH_00029 4.4e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFHCACOH_00030 2.1e-148 E GDSL-like Lipase/Acylhydrolase family
HFHCACOH_00031 9.2e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HFHCACOH_00032 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFHCACOH_00033 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HFHCACOH_00034 2.4e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFHCACOH_00035 4.5e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HFHCACOH_00036 2.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFHCACOH_00037 3.2e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFHCACOH_00038 3.2e-192 L Transposase and inactivated derivatives, IS30 family
HFHCACOH_00039 9.2e-259 yfnA E amino acid
HFHCACOH_00040 7.2e-12
HFHCACOH_00041 1.7e-289 pipD E Dipeptidase
HFHCACOH_00042 1.3e-166 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFHCACOH_00043 0.0 smc D Required for chromosome condensation and partitioning
HFHCACOH_00044 1.3e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFHCACOH_00045 1.5e-25 oppA E ABC transporter substrate-binding protein
HFHCACOH_00046 1.7e-81 oppA E ABC transporter substrate-binding protein
HFHCACOH_00047 2.4e-28 oppA E ABC transporter substrate-binding protein
HFHCACOH_00048 0.0 oppA E ABC transporter substrate-binding protein
HFHCACOH_00049 5.2e-146 oppC P Binding-protein-dependent transport system inner membrane component
HFHCACOH_00050 5e-176 oppB P ABC transporter permease
HFHCACOH_00051 5.3e-181 oppF P Belongs to the ABC transporter superfamily
HFHCACOH_00052 3.4e-194 oppD P Belongs to the ABC transporter superfamily
HFHCACOH_00053 2.2e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFHCACOH_00054 2.1e-180 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFHCACOH_00055 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFHCACOH_00056 1.7e-304 yloV S DAK2 domain fusion protein YloV
HFHCACOH_00057 1.5e-56 asp S Asp23 family, cell envelope-related function
HFHCACOH_00058 9.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HFHCACOH_00059 3.1e-30
HFHCACOH_00060 1.4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HFHCACOH_00061 9.4e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HFHCACOH_00062 4.4e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFHCACOH_00063 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HFHCACOH_00064 3.5e-146 stp 3.1.3.16 T phosphatase
HFHCACOH_00065 1.9e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFHCACOH_00066 1.4e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFHCACOH_00067 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFHCACOH_00068 6.5e-34 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFHCACOH_00069 4.3e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HFHCACOH_00070 6.5e-78 6.3.3.2 S ASCH
HFHCACOH_00071 6.9e-306 recN L May be involved in recombinational repair of damaged DNA
HFHCACOH_00072 2.8e-151 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HFHCACOH_00073 7e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFHCACOH_00074 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFHCACOH_00075 1.1e-175 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFHCACOH_00076 3.1e-101 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFHCACOH_00077 4e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFHCACOH_00078 2.4e-69 yqhY S Asp23 family, cell envelope-related function
HFHCACOH_00079 1.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFHCACOH_00080 8.9e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HFHCACOH_00081 2.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HFHCACOH_00082 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HFHCACOH_00083 1e-254 S Uncharacterized protein conserved in bacteria (DUF2325)
HFHCACOH_00084 1.5e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HFHCACOH_00085 9.5e-129 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HFHCACOH_00086 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HFHCACOH_00087 0.0 S Predicted membrane protein (DUF2207)
HFHCACOH_00088 5e-213 M Glycosyl hydrolases family 25
HFHCACOH_00090 2.1e-49 scrR K Transcriptional regulator, LacI family
HFHCACOH_00091 5.5e-107 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HFHCACOH_00092 7.9e-48
HFHCACOH_00093 3.3e-89
HFHCACOH_00094 1.7e-70
HFHCACOH_00096 3.2e-34
HFHCACOH_00099 1.1e-23
HFHCACOH_00100 2.3e-28
HFHCACOH_00101 8.5e-17 K Transcriptional regulator
HFHCACOH_00102 4.8e-157 sip L Belongs to the 'phage' integrase family
HFHCACOH_00103 3e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFHCACOH_00104 2e-289 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFHCACOH_00105 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFHCACOH_00106 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFHCACOH_00107 1.6e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFHCACOH_00108 9.7e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFHCACOH_00109 2.8e-38 yajC U Preprotein translocase
HFHCACOH_00110 4.5e-285 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFHCACOH_00111 2.7e-213 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFHCACOH_00112 3.6e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HFHCACOH_00113 7.5e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFHCACOH_00114 4.2e-64
HFHCACOH_00115 1.9e-86
HFHCACOH_00116 2e-42 yrzL S Belongs to the UPF0297 family
HFHCACOH_00117 1.1e-71 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFHCACOH_00118 6.2e-51 yrzB S Belongs to the UPF0473 family
HFHCACOH_00119 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFHCACOH_00120 1e-53 trxA O Belongs to the thioredoxin family
HFHCACOH_00121 1.2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFHCACOH_00122 7.6e-175 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCACOH_00123 2e-59 K Helix-turn-helix domain, rpiR family
HFHCACOH_00124 2.3e-90
HFHCACOH_00125 1.3e-37 KQ helix_turn_helix, mercury resistance
HFHCACOH_00127 7.3e-135 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HFHCACOH_00128 9.1e-206 csaB M Glycosyl transferases group 1
HFHCACOH_00129 8.6e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFHCACOH_00130 6.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFHCACOH_00131 1.7e-81 S Membrane protein involved in the export of O-antigen and teichoic acid
HFHCACOH_00132 2.7e-182 licA 2.7.1.89 M Nucleotidyl transferase
HFHCACOH_00133 4.2e-79 M Nucleotidyl transferase
HFHCACOH_00134 2.6e-171 caiT U Belongs to the BCCT transporter (TC 2.A.15) family
HFHCACOH_00135 4.2e-30 L hmm pf00665
HFHCACOH_00136 5.1e-109 L Helix-turn-helix domain
HFHCACOH_00137 4.7e-160 htpX O Belongs to the peptidase M48B family
HFHCACOH_00138 2.3e-96 lemA S LemA family
HFHCACOH_00139 3.4e-192 ybiR P Citrate transporter
HFHCACOH_00140 8.6e-69 S Iron-sulphur cluster biosynthesis
HFHCACOH_00141 1.2e-61 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HFHCACOH_00142 1.9e-16 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HFHCACOH_00143 1e-44
HFHCACOH_00144 3.2e-54 S Domain of unknown function (DUF5067)
HFHCACOH_00145 6.3e-63
HFHCACOH_00148 4.3e-120 XK27_07525 3.6.1.55 F NUDIX domain
HFHCACOH_00149 6.2e-145 2.4.2.3 F Phosphorylase superfamily
HFHCACOH_00150 4.9e-75 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
HFHCACOH_00152 6.1e-79 K Acetyltransferase (GNAT) domain
HFHCACOH_00153 4.2e-53
HFHCACOH_00154 4.4e-16 S Plasmid replication protein
HFHCACOH_00155 4e-193 glf 5.4.99.9 M UDP-galactopyranose mutase
HFHCACOH_00156 3.1e-96 wbbI M transferase activity, transferring glycosyl groups
HFHCACOH_00157 6.5e-178 I Carboxylesterase family
HFHCACOH_00158 1.1e-64 arsC 1.20.4.1 P Belongs to the ArsC family
HFHCACOH_00159 4e-27
HFHCACOH_00160 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HFHCACOH_00161 4.6e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HFHCACOH_00162 2.3e-218 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HFHCACOH_00163 6e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HFHCACOH_00164 4.2e-46
HFHCACOH_00165 7.7e-19 D Alpha beta
HFHCACOH_00166 7.5e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HFHCACOH_00167 1.4e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HFHCACOH_00168 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HFHCACOH_00169 1.1e-103 E GDSL-like Lipase/Acylhydrolase
HFHCACOH_00170 3.9e-170 coaA 2.7.1.33 F Pantothenic acid kinase
HFHCACOH_00171 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFHCACOH_00172 5.5e-226 G Bacterial extracellular solute-binding protein
HFHCACOH_00173 5.2e-66 S Peptidase propeptide and YPEB domain
HFHCACOH_00174 0.0 G Belongs to the glycosyl hydrolase 31 family
HFHCACOH_00175 2.9e-31
HFHCACOH_00176 8.1e-102 I alpha/beta hydrolase fold
HFHCACOH_00177 7.6e-130 yibF S overlaps another CDS with the same product name
HFHCACOH_00178 3.1e-201 yibE S overlaps another CDS with the same product name
HFHCACOH_00179 7.5e-95
HFHCACOH_00180 6.9e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HFHCACOH_00181 3.2e-231 S Cysteine-rich secretory protein family
HFHCACOH_00182 1.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFHCACOH_00183 1.2e-261 glnPH2 P ABC transporter permease
HFHCACOH_00184 1e-129
HFHCACOH_00185 4.3e-121 luxT K Bacterial regulatory proteins, tetR family
HFHCACOH_00186 1.6e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFHCACOH_00187 6.8e-30
HFHCACOH_00188 1.4e-104 GM NmrA-like family
HFHCACOH_00189 2.1e-125 S Alpha/beta hydrolase family
HFHCACOH_00190 6.2e-159 epsV 2.7.8.12 S glycosyl transferase family 2
HFHCACOH_00191 2.2e-139 ypuA S Protein of unknown function (DUF1002)
HFHCACOH_00192 5.6e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFHCACOH_00193 1e-178 S Alpha/beta hydrolase of unknown function (DUF915)
HFHCACOH_00194 3.8e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFHCACOH_00195 5.9e-85
HFHCACOH_00196 4.3e-132 cobB K SIR2 family
HFHCACOH_00197 1.2e-91 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HFHCACOH_00198 1.9e-120 terC P Integral membrane protein TerC family
HFHCACOH_00199 4.1e-62 yeaO S Protein of unknown function, DUF488
HFHCACOH_00200 2.3e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HFHCACOH_00201 5.1e-290 glnP P ABC transporter permease
HFHCACOH_00202 3.3e-138 glnQ E ABC transporter, ATP-binding protein
HFHCACOH_00203 4.9e-159 L HNH nucleases
HFHCACOH_00204 1.4e-118 yfbR S HD containing hydrolase-like enzyme
HFHCACOH_00206 1.5e-18 S Peptidase propeptide and YPEB domain
HFHCACOH_00207 2.5e-64 G Glycosyl hydrolases family 8
HFHCACOH_00208 1.7e-57 G Glycosyl hydrolases family 8
HFHCACOH_00209 2e-78
HFHCACOH_00210 0.0 3.6.3.8 P P-type ATPase
HFHCACOH_00211 4.9e-35 yufQ S Belongs to the binding-protein-dependent transport system permease family
HFHCACOH_00212 9e-58 yufQ S Belongs to the binding-protein-dependent transport system permease family
HFHCACOH_00213 1.1e-26 yufQ S Belongs to the binding-protein-dependent transport system permease family
HFHCACOH_00214 1.9e-57 yufP S Belongs to the binding-protein-dependent transport system permease family
HFHCACOH_00215 4.5e-56 K response regulator
HFHCACOH_00216 9.4e-41 sptS 2.7.13.3 T Histidine kinase
HFHCACOH_00217 1.2e-116 sptS 2.7.13.3 T Histidine kinase
HFHCACOH_00218 5.5e-209 EGP Major facilitator Superfamily
HFHCACOH_00219 3.7e-72 O OsmC-like protein
HFHCACOH_00220 2.3e-125 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
HFHCACOH_00221 6.1e-190 licA 2.7.1.89 M Nucleotidyl transferase
HFHCACOH_00222 5.9e-159 caiT U Belongs to the BCCT transporter (TC 2.A.15) family
HFHCACOH_00223 2.3e-71 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HFHCACOH_00225 1.1e-148 ydiM G Major facilitator superfamily
HFHCACOH_00226 3.6e-08 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFHCACOH_00227 2.2e-145 fabF-1 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFHCACOH_00228 1.5e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFHCACOH_00229 6.9e-228 mtnE 2.6.1.83 E Aminotransferase
HFHCACOH_00230 1.1e-149 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HFHCACOH_00231 8.8e-34 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFHCACOH_00232 5.6e-139 mdeA 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HFHCACOH_00235 6.5e-232 ycaM E amino acid
HFHCACOH_00236 4.4e-149 S haloacid dehalogenase-like hydrolase
HFHCACOH_00237 0.0 S SH3-like domain
HFHCACOH_00238 0.0 uvrA2 L ABC transporter
HFHCACOH_00240 9.8e-286 V ABC-type multidrug transport system, ATPase and permease components
HFHCACOH_00241 3.6e-288 V ABC-type multidrug transport system, ATPase and permease components
HFHCACOH_00243 6.7e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFHCACOH_00244 1e-69 yqhL P Rhodanese-like protein
HFHCACOH_00245 7.3e-33 yqgQ S Bacterial protein of unknown function (DUF910)
HFHCACOH_00246 6.8e-119 gluP 3.4.21.105 S Rhomboid family
HFHCACOH_00247 1.7e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFHCACOH_00248 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HFHCACOH_00249 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HFHCACOH_00250 0.0 S membrane
HFHCACOH_00251 4e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HFHCACOH_00252 2.4e-38 K Helix-turn-helix domain
HFHCACOH_00253 9e-57 S Phage derived protein Gp49-like (DUF891)
HFHCACOH_00254 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HFHCACOH_00255 9.2e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFHCACOH_00256 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFHCACOH_00257 1.8e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFHCACOH_00258 3.6e-63 yodB K Transcriptional regulator, HxlR family
HFHCACOH_00259 3e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFHCACOH_00260 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HFHCACOH_00261 7.6e-156 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFHCACOH_00262 2.5e-83 S Aminoacyl-tRNA editing domain
HFHCACOH_00263 3.5e-275 arlS 2.7.13.3 T Histidine kinase
HFHCACOH_00264 3.2e-127 K response regulator
HFHCACOH_00265 1.7e-96 yceD S Uncharacterized ACR, COG1399
HFHCACOH_00266 5e-215 ylbM S Belongs to the UPF0348 family
HFHCACOH_00267 2.6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFHCACOH_00268 2.3e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HFHCACOH_00269 5.4e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFHCACOH_00270 3.8e-212 yqeH S Ribosome biogenesis GTPase YqeH
HFHCACOH_00271 3.8e-93 yqeG S HAD phosphatase, family IIIA
HFHCACOH_00272 2.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFHCACOH_00273 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HFHCACOH_00274 6.2e-55 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFHCACOH_00275 1e-27 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HFHCACOH_00276 1.2e-199 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HFHCACOH_00277 2.3e-55 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HFHCACOH_00278 5.2e-181 S Domain of unknown function (DUF389)
HFHCACOH_00280 1.5e-10
HFHCACOH_00281 9.1e-113 ropB K Transcriptional regulator
HFHCACOH_00282 1.3e-216 EGP Major facilitator Superfamily
HFHCACOH_00283 3.9e-24 ropB K Transcriptional regulator
HFHCACOH_00284 1.9e-172 mrr L restriction endonuclease
HFHCACOH_00285 2.8e-36 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HFHCACOH_00286 2e-57 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HFHCACOH_00287 1.9e-97
HFHCACOH_00289 2.2e-154 glcU U sugar transport
HFHCACOH_00290 3.2e-231 L Transposase
HFHCACOH_00291 2.8e-91 L Resolvase, N terminal domain
HFHCACOH_00292 2.9e-243 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFHCACOH_00293 1.5e-130 L Belongs to the 'phage' integrase family
HFHCACOH_00294 2.2e-100 nhaC C Na H antiporter NhaC
HFHCACOH_00295 5.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFHCACOH_00296 1.1e-276 V ABC transporter transmembrane region
HFHCACOH_00297 9.3e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HFHCACOH_00298 2.4e-223 oxlT P Major Facilitator Superfamily
HFHCACOH_00299 2.8e-91 L Helix-turn-helix domain
HFHCACOH_00300 1.7e-81 L HTH-like domain
HFHCACOH_00301 9e-167 K SIR2-like domain
HFHCACOH_00303 3.1e-81 racA K Domain of unknown function (DUF1836)
HFHCACOH_00304 1.8e-153 yitS S EDD domain protein, DegV family
HFHCACOH_00306 2.3e-148
HFHCACOH_00307 2.8e-123 skfE V ATPases associated with a variety of cellular activities
HFHCACOH_00308 3.9e-60 yvoA_1 K Transcriptional regulator, GntR family
HFHCACOH_00309 2.6e-61 S Uncharacterised protein family (UPF0236)
HFHCACOH_00310 0.0 typA T GTP-binding protein TypA
HFHCACOH_00311 2.6e-206 ftsW D Belongs to the SEDS family
HFHCACOH_00312 7.3e-53 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HFHCACOH_00313 2.9e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HFHCACOH_00314 6.8e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFHCACOH_00315 1e-190 ylbL T Belongs to the peptidase S16 family
HFHCACOH_00316 4e-82 comEA L Competence protein ComEA
HFHCACOH_00317 0.0 comEC S Competence protein ComEC
HFHCACOH_00318 1.8e-173 holA 2.7.7.7 L DNA polymerase III delta subunit
HFHCACOH_00319 3.3e-34 rpsT J Binds directly to 16S ribosomal RNA
HFHCACOH_00320 7e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFHCACOH_00321 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFHCACOH_00322 8.3e-151
HFHCACOH_00323 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFHCACOH_00324 2.2e-206 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFHCACOH_00325 1.7e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFHCACOH_00326 4.1e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
HFHCACOH_00327 9.8e-55 yjeM E Amino Acid
HFHCACOH_00328 4.7e-180 yjeM E Amino Acid
HFHCACOH_00329 9.2e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFHCACOH_00330 1.8e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HFHCACOH_00331 1.5e-247 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFHCACOH_00332 5.2e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFHCACOH_00333 7.5e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFHCACOH_00334 2.7e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFHCACOH_00335 4.3e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFHCACOH_00336 2e-214 aspC 2.6.1.1 E Aminotransferase
HFHCACOH_00337 1.7e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFHCACOH_00338 6.7e-63
HFHCACOH_00339 3.2e-115 L Integrase
HFHCACOH_00340 3.6e-106 K Helix-turn-helix domain
HFHCACOH_00341 4.6e-29
HFHCACOH_00342 3.3e-141 soj D AAA domain
HFHCACOH_00343 2.1e-84 3.6.3.44 V ABC transporter transmembrane region
HFHCACOH_00346 2.6e-109 S ABC-2 family transporter protein
HFHCACOH_00347 3.5e-52 S ABC transporter
HFHCACOH_00348 6.5e-111 K helix_turn_helix, mercury resistance
HFHCACOH_00349 9.7e-231 pbuG S permease
HFHCACOH_00350 7.7e-172
HFHCACOH_00351 6e-214 mdtG EGP Major facilitator Superfamily
HFHCACOH_00352 3.2e-75 ntd 2.4.2.6 F Nucleoside
HFHCACOH_00353 1.4e-89 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFHCACOH_00354 9.1e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HFHCACOH_00355 3.3e-183 S Bacteriocin helveticin-J
HFHCACOH_00356 7.2e-176 S SLAP domain
HFHCACOH_00357 2.1e-256 mntH P H( )-stimulated, divalent metal cation uptake system
HFHCACOH_00358 7.6e-55 T Universal stress protein family
HFHCACOH_00359 1.6e-241 amtB P ammonium transporter
HFHCACOH_00360 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HFHCACOH_00361 2.2e-152 yihY S Belongs to the UPF0761 family
HFHCACOH_00362 7.2e-163 map 3.4.11.18 E Methionine Aminopeptidase
HFHCACOH_00363 5.9e-79 fld C Flavodoxin
HFHCACOH_00364 5.3e-90 gtcA S Teichoic acid glycosylation protein
HFHCACOH_00365 1.7e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFHCACOH_00367 2.7e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCACOH_00368 7.8e-206 yfmL 3.6.4.13 L DEAD DEAH box helicase
HFHCACOH_00369 2.3e-130 M Glycosyl hydrolases family 25
HFHCACOH_00370 7.7e-50 potE E amino acid
HFHCACOH_00371 4e-140 potE E amino acid
HFHCACOH_00372 2.2e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HFHCACOH_00373 7.7e-239 yhdP S Transporter associated domain
HFHCACOH_00374 1.2e-49 C nitroreductase
HFHCACOH_00375 7.1e-18 C nitroreductase
HFHCACOH_00376 2.8e-39
HFHCACOH_00377 4.2e-86 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HFHCACOH_00378 1.9e-73
HFHCACOH_00379 1.4e-29 glvR K Helix-turn-helix domain, rpiR family
HFHCACOH_00380 6.8e-44 glvR K Helix-turn-helix domain, rpiR family
HFHCACOH_00381 0.0 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HFHCACOH_00382 1.7e-86 S hydrolase
HFHCACOH_00383 3.3e-11 2.7.13.3 T GHKL domain
HFHCACOH_00384 1.5e-160 rssA S Phospholipase, patatin family
HFHCACOH_00385 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HFHCACOH_00386 4.6e-132 glcR K DeoR C terminal sensor domain
HFHCACOH_00387 1.9e-62 S Enterocin A Immunity
HFHCACOH_00388 2.8e-54 yitW S Iron-sulfur cluster assembly protein
HFHCACOH_00389 1.2e-271 sufB O assembly protein SufB
HFHCACOH_00390 3.2e-80 nifU C SUF system FeS assembly protein, NifU family
HFHCACOH_00391 9.5e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFHCACOH_00392 1.1e-223 sufD O FeS assembly protein SufD
HFHCACOH_00393 1e-145 sufC O FeS assembly ATPase SufC
HFHCACOH_00394 3.3e-217 yceI EGP Major facilitator Superfamily
HFHCACOH_00395 6.8e-153 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
HFHCACOH_00396 4.3e-130 ybbM S Uncharacterised protein family (UPF0014)
HFHCACOH_00397 1.2e-112 ybbL S ABC transporter, ATP-binding protein
HFHCACOH_00398 2.5e-29 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HFHCACOH_00400 1.6e-17 L Transposase
HFHCACOH_00401 3.8e-139 pnuC H nicotinamide mononucleotide transporter
HFHCACOH_00402 2.7e-63 S Protein of unknown function (DUF3290)
HFHCACOH_00403 1.1e-92
HFHCACOH_00404 1.9e-46
HFHCACOH_00405 3.5e-45
HFHCACOH_00406 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFHCACOH_00407 5.4e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HFHCACOH_00408 5e-69 yslB S Protein of unknown function (DUF2507)
HFHCACOH_00409 1.3e-58 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFHCACOH_00410 6.3e-254 pepC 3.4.22.40 E aminopeptidase
HFHCACOH_00413 1.7e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFHCACOH_00414 1.6e-166 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFHCACOH_00415 3.8e-72 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFHCACOH_00416 1.6e-28 cspA K Cold shock protein
HFHCACOH_00417 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFHCACOH_00418 3.2e-242 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFHCACOH_00419 0.0 oatA I Acyltransferase
HFHCACOH_00420 1.7e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFHCACOH_00421 1.8e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HFHCACOH_00422 1e-22 yrvD S Lipopolysaccharide assembly protein A domain
HFHCACOH_00423 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HFHCACOH_00424 2.6e-307 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HFHCACOH_00425 2.5e-22 S Protein of unknown function (DUF2929)
HFHCACOH_00426 0.0 dnaE 2.7.7.7 L DNA polymerase
HFHCACOH_00427 6.6e-184 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HFHCACOH_00428 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HFHCACOH_00429 3.6e-168 cvfB S S1 domain
HFHCACOH_00430 5.2e-167 xerD D recombinase XerD
HFHCACOH_00431 4.9e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFHCACOH_00432 7.4e-62 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFHCACOH_00433 2.3e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFHCACOH_00434 8.5e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HFHCACOH_00435 1e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFHCACOH_00436 5.3e-30 yocH M Lysin motif
HFHCACOH_00437 3.8e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HFHCACOH_00438 9.1e-207 rpsA 1.17.7.4 J Ribosomal protein S1
HFHCACOH_00439 8.2e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HFHCACOH_00440 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFHCACOH_00441 2.3e-229 S Tetratricopeptide repeat protein
HFHCACOH_00442 3.2e-161 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFHCACOH_00443 6.6e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFHCACOH_00444 5.5e-158 msmR7 K helix_turn_helix, arabinose operon control protein
HFHCACOH_00445 7.6e-85 M LysM domain
HFHCACOH_00446 8.1e-123
HFHCACOH_00448 2.2e-26 cysE_1 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HFHCACOH_00449 2.1e-42 S Enterocin A Immunity
HFHCACOH_00450 2.9e-48 lctP C L-lactate permease
HFHCACOH_00451 4.6e-85 lctP C L-lactate permease
HFHCACOH_00452 5.2e-24 lctP C L-lactate permease
HFHCACOH_00453 1e-256 L Probable transposase
HFHCACOH_00454 5e-48 M Glycosyltransferase like family 2
HFHCACOH_00455 2.5e-80 tnp2PF3 L Transposase DDE domain
HFHCACOH_00456 5.9e-20 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HFHCACOH_00457 3e-104 S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HFHCACOH_00458 9.3e-77 L COG3547 Transposase and inactivated derivatives
HFHCACOH_00459 7.5e-40
HFHCACOH_00460 4.1e-125 S Fic/DOC family
HFHCACOH_00461 3e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HFHCACOH_00462 2.7e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFHCACOH_00463 1.4e-178 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFHCACOH_00464 4.4e-24
HFHCACOH_00465 2.3e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFHCACOH_00466 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFHCACOH_00467 7.2e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFHCACOH_00468 2.6e-134 comFC S Competence protein
HFHCACOH_00469 2.1e-246 comFA L Helicase C-terminal domain protein
HFHCACOH_00470 7.6e-115 yvyE 3.4.13.9 S YigZ family
HFHCACOH_00471 1.9e-209 tagO 2.7.8.33, 2.7.8.35 M transferase
HFHCACOH_00472 8.1e-219 rny S Endoribonuclease that initiates mRNA decay
HFHCACOH_00473 6.7e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFHCACOH_00474 1.9e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFHCACOH_00475 1.2e-120 ymfM S Helix-turn-helix domain
HFHCACOH_00476 1e-133 IQ Enoyl-(Acyl carrier protein) reductase
HFHCACOH_00477 9.6e-236 S Peptidase M16
HFHCACOH_00478 4.3e-225 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HFHCACOH_00479 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HFHCACOH_00480 1.4e-68 WQ51_03320 S Protein of unknown function (DUF1149)
HFHCACOH_00481 5.5e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFHCACOH_00482 1.9e-212 yubA S AI-2E family transporter
HFHCACOH_00483 3.7e-23 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HFHCACOH_00484 2.9e-27 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HFHCACOH_00485 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HFHCACOH_00486 2.8e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HFHCACOH_00487 3.2e-207 G Major Facilitator Superfamily
HFHCACOH_00488 2.6e-225 traA L MobA/MobL family
HFHCACOH_00489 2.2e-97 L Integrase
HFHCACOH_00491 1.5e-112
HFHCACOH_00492 9.2e-22
HFHCACOH_00493 9.6e-47
HFHCACOH_00494 1.9e-49
HFHCACOH_00495 2.7e-17
HFHCACOH_00496 1.6e-176 lacX 5.1.3.3 G Aldose 1-epimerase
HFHCACOH_00497 2.2e-221 L Transposase
HFHCACOH_00499 1.2e-13 L Transposase
HFHCACOH_00500 6.1e-188 cggR K Putative sugar-binding domain
HFHCACOH_00501 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFHCACOH_00502 1.3e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HFHCACOH_00503 1.2e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFHCACOH_00504 1.8e-95
HFHCACOH_00505 7.4e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
HFHCACOH_00506 2.8e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFHCACOH_00507 7e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HFHCACOH_00508 6.4e-90 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HFHCACOH_00509 1.4e-98 dnaQ 2.7.7.7 L DNA polymerase III
HFHCACOH_00510 5.4e-164 murB 1.3.1.98 M Cell wall formation
HFHCACOH_00511 5.9e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFHCACOH_00512 6.6e-129 potB P ABC transporter permease
HFHCACOH_00513 1.9e-115 potC P ABC transporter permease
HFHCACOH_00514 1.2e-205 potD P ABC transporter
HFHCACOH_00515 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFHCACOH_00516 1.6e-169 ybbR S YbbR-like protein
HFHCACOH_00517 6.3e-257 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFHCACOH_00518 2e-149 S hydrolase
HFHCACOH_00519 1.9e-147 S Sucrose-6F-phosphate phosphohydrolase
HFHCACOH_00520 7.9e-118
HFHCACOH_00521 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFHCACOH_00522 6.6e-215 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HFHCACOH_00523 2.7e-86 licT K CAT RNA binding domain
HFHCACOH_00524 8.3e-48 licT K CAT RNA binding domain
HFHCACOH_00525 0.0 bglP G phosphotransferase system
HFHCACOH_00526 1.8e-50 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCACOH_00527 2.7e-240 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCACOH_00528 4.2e-183 D Alpha beta
HFHCACOH_00529 3e-290 E Amino acid permease
HFHCACOH_00530 1.3e-16 S amino acid activation for nonribosomal peptide biosynthetic process
HFHCACOH_00531 3.6e-151 xerD L Phage integrase, N-terminal SAM-like domain
HFHCACOH_00532 1.9e-07 L COG2963 Transposase and inactivated derivatives
HFHCACOH_00533 6.5e-159
HFHCACOH_00535 9e-95 L Probable transposase
HFHCACOH_00536 3.2e-124 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HFHCACOH_00537 9.9e-139 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFHCACOH_00538 8e-24 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFHCACOH_00539 2e-106 K Bacterial regulatory proteins, tetR family
HFHCACOH_00540 3.7e-232 V Restriction endonuclease
HFHCACOH_00541 4.3e-59 pipD E Dipeptidase
HFHCACOH_00542 7.6e-234 S LPXTG cell wall anchor motif
HFHCACOH_00543 3e-147 S Putative ABC-transporter type IV
HFHCACOH_00544 1.2e-97 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
HFHCACOH_00545 1.7e-85 S ECF transporter, substrate-specific component
HFHCACOH_00546 3.9e-58 S Domain of unknown function (DUF4430)
HFHCACOH_00547 1.8e-101 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HFHCACOH_00548 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HFHCACOH_00549 1.2e-104 K AI-2E family transporter
HFHCACOH_00550 6.8e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HFHCACOH_00551 1.3e-11
HFHCACOH_00552 3.2e-51
HFHCACOH_00553 3.6e-137 XK27_08845 S ABC transporter, ATP-binding protein
HFHCACOH_00554 2.2e-125 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HFHCACOH_00555 4.2e-178 ABC-SBP S ABC transporter
HFHCACOH_00556 2.1e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HFHCACOH_00558 6.8e-28
HFHCACOH_00559 8.4e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFHCACOH_00560 2.3e-169 yniA G Phosphotransferase enzyme family
HFHCACOH_00561 2.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
HFHCACOH_00562 9.9e-261 E amino acid
HFHCACOH_00563 0.0 L Helicase C-terminal domain protein
HFHCACOH_00564 3e-195 pbpX1 V Beta-lactamase
HFHCACOH_00565 7.9e-70 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HFHCACOH_00578 1.8e-32
HFHCACOH_00579 9.5e-25 cspC K Probable zinc-ribbon domain
HFHCACOH_00580 1.1e-33
HFHCACOH_00581 2.7e-22 ykuL S IMP dehydrogenase activity
HFHCACOH_00582 1.8e-212 ywhK S Membrane
HFHCACOH_00583 3.8e-50
HFHCACOH_00584 5.2e-19 S D-Ala-teichoic acid biosynthesis protein
HFHCACOH_00585 2.3e-292 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFHCACOH_00586 3e-242 dltB M MBOAT, membrane-bound O-acyltransferase family
HFHCACOH_00587 5.7e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFHCACOH_00588 1.3e-248 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFHCACOH_00589 6e-174 pbpX2 V Beta-lactamase
HFHCACOH_00591 2e-10
HFHCACOH_00592 1.1e-119 S CAAX protease self-immunity
HFHCACOH_00593 1.3e-29
HFHCACOH_00594 1.8e-32
HFHCACOH_00596 9.6e-16
HFHCACOH_00597 3.5e-123 S Protein of unknown function (DUF975)
HFHCACOH_00598 7.6e-148 lysA2 M Glycosyl hydrolases family 25
HFHCACOH_00599 1.7e-285 ytgP S Polysaccharide biosynthesis protein
HFHCACOH_00600 1.2e-35
HFHCACOH_00601 6.1e-193 XK27_06780 V ABC transporter permease
HFHCACOH_00602 6e-114 XK27_06780 V ABC transporter permease
HFHCACOH_00603 1.9e-124 XK27_06785 V ABC transporter, ATP-binding protein
HFHCACOH_00604 6.2e-211 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCACOH_00605 6e-157 S Alpha/beta hydrolase of unknown function (DUF915)
HFHCACOH_00606 0.0 clpE O AAA domain (Cdc48 subfamily)
HFHCACOH_00607 6.7e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HFHCACOH_00608 6.9e-128
HFHCACOH_00609 1.8e-209 cycA E Amino acid permease
HFHCACOH_00610 4.3e-245 yifK E Amino acid permease
HFHCACOH_00611 4.8e-33 S Transglycosylase associated protein
HFHCACOH_00612 5.6e-27
HFHCACOH_00615 6.2e-20
HFHCACOH_00616 1.7e-23
HFHCACOH_00617 5.2e-10
HFHCACOH_00618 1.1e-28
HFHCACOH_00619 3.4e-76 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HFHCACOH_00620 1.6e-31 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HFHCACOH_00621 4.6e-37 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HFHCACOH_00622 4.6e-118 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HFHCACOH_00623 1.3e-54 2.4.1.83 GT2 S GtrA-like protein
HFHCACOH_00624 2.8e-155 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HFHCACOH_00626 3.9e-270 3.6.3.8 P P-type ATPase
HFHCACOH_00627 7.7e-136 3.6.3.8 P P-type ATPase
HFHCACOH_00628 9.2e-159
HFHCACOH_00629 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFHCACOH_00630 1.4e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HFHCACOH_00631 5.7e-126 S Haloacid dehalogenase-like hydrolase
HFHCACOH_00632 2.1e-114 radC L DNA repair protein
HFHCACOH_00633 4.2e-173 mreB D cell shape determining protein MreB
HFHCACOH_00634 3e-148 mreC M Involved in formation and maintenance of cell shape
HFHCACOH_00635 9.3e-95 mreD
HFHCACOH_00636 9.4e-12 S Protein of unknown function (DUF4044)
HFHCACOH_00637 2.2e-54 S Protein of unknown function (DUF3397)
HFHCACOH_00638 1.7e-75 mraZ K Belongs to the MraZ family
HFHCACOH_00639 7.5e-183 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFHCACOH_00640 9.1e-54 ftsL D Cell division protein FtsL
HFHCACOH_00641 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HFHCACOH_00642 7.1e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFHCACOH_00643 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFHCACOH_00644 8.8e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFHCACOH_00645 2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFHCACOH_00646 8.8e-235 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFHCACOH_00647 1.6e-204 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFHCACOH_00648 1.3e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFHCACOH_00649 9e-47 yggT S YGGT family
HFHCACOH_00650 4.8e-148 ylmH S S4 domain protein
HFHCACOH_00651 9.8e-101 gpsB D DivIVA domain protein
HFHCACOH_00652 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFHCACOH_00653 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
HFHCACOH_00654 1.7e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HFHCACOH_00655 1.9e-39
HFHCACOH_00656 3.8e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFHCACOH_00657 1.3e-215 iscS 2.8.1.7 E Aminotransferase class V
HFHCACOH_00658 1.4e-56 XK27_04120 S Putative amino acid metabolism
HFHCACOH_00659 6e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFHCACOH_00660 6.8e-124 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HFHCACOH_00661 3.8e-103 S Repeat protein
HFHCACOH_00662 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFHCACOH_00663 1.6e-118 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HFHCACOH_00664 2.3e-29 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HFHCACOH_00665 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFHCACOH_00666 4.2e-33 ykzG S Belongs to the UPF0356 family
HFHCACOH_00667 1.5e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFHCACOH_00668 3.1e-49 2.7.7.12 C Domain of unknown function (DUF4931)
HFHCACOH_00669 1.2e-120
HFHCACOH_00670 3.2e-141 S Belongs to the UPF0246 family
HFHCACOH_00671 1.6e-140 aroD S Alpha/beta hydrolase family
HFHCACOH_00672 1.2e-111 G phosphoglycerate mutase
HFHCACOH_00673 7e-95 ygfC K Bacterial regulatory proteins, tetR family
HFHCACOH_00674 1.7e-164 hrtB V ABC transporter permease
HFHCACOH_00675 9.1e-116 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HFHCACOH_00676 1.4e-275 pipD E Dipeptidase
HFHCACOH_00677 8e-38
HFHCACOH_00678 8.2e-111 K WHG domain
HFHCACOH_00679 2.1e-94 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HFHCACOH_00680 5.9e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
HFHCACOH_00681 2.8e-148 3.1.3.48 T Tyrosine phosphatase family
HFHCACOH_00682 1.2e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFHCACOH_00683 7.3e-84 cvpA S Colicin V production protein
HFHCACOH_00684 7e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HFHCACOH_00685 5.1e-148 noc K Belongs to the ParB family
HFHCACOH_00686 1.9e-136 soj D Sporulation initiation inhibitor
HFHCACOH_00687 5.9e-155 spo0J K Belongs to the ParB family
HFHCACOH_00688 3.7e-44 yyzM S Bacterial protein of unknown function (DUF951)
HFHCACOH_00689 1.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFHCACOH_00690 1.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
HFHCACOH_00691 3.5e-297 V ABC transporter, ATP-binding protein
HFHCACOH_00692 0.0 V ABC transporter
HFHCACOH_00693 5.1e-122 K response regulator
HFHCACOH_00694 2.7e-208 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HFHCACOH_00695 1.2e-304 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFHCACOH_00696 3.7e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HFHCACOH_00697 7e-172 S Archaea bacterial proteins of unknown function
HFHCACOH_00698 1.8e-224 pbuG S permease
HFHCACOH_00699 2.3e-35
HFHCACOH_00700 9.3e-77 atkY K Penicillinase repressor
HFHCACOH_00701 1.2e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HFHCACOH_00702 1.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HFHCACOH_00703 0.0 copA 3.6.3.54 P P-type ATPase
HFHCACOH_00704 1.7e-21 EGP Sugar (and other) transporter
HFHCACOH_00705 5.3e-157 EGP Sugar (and other) transporter
HFHCACOH_00706 1.2e-18
HFHCACOH_00707 3.8e-212
HFHCACOH_00708 3.2e-281 clcA P chloride
HFHCACOH_00709 4.3e-269 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFHCACOH_00710 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFHCACOH_00711 5.6e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFHCACOH_00712 1e-143 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFHCACOH_00713 1e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFHCACOH_00714 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HFHCACOH_00715 1.8e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFHCACOH_00716 8.8e-196 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFHCACOH_00717 1.4e-33 yaaA S S4 domain protein YaaA
HFHCACOH_00718 2.6e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFHCACOH_00719 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFHCACOH_00720 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFHCACOH_00721 4.7e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HFHCACOH_00722 3.4e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFHCACOH_00723 3.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFHCACOH_00724 7e-13 ytgB S Transglycosylase associated protein
HFHCACOH_00725 1.9e-130
HFHCACOH_00726 1.1e-32 rarA L recombination factor protein RarA
HFHCACOH_00727 9.5e-41 rarA L recombination factor protein RarA
HFHCACOH_00728 7.8e-61 rarA L recombination factor protein RarA
HFHCACOH_00729 7.8e-28
HFHCACOH_00730 3e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HFHCACOH_00731 2.7e-140
HFHCACOH_00732 2.5e-178
HFHCACOH_00733 2.8e-260 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HFHCACOH_00734 2.8e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFHCACOH_00735 4.2e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HFHCACOH_00736 4.9e-179 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HFHCACOH_00737 3.6e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HFHCACOH_00738 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HFHCACOH_00739 1.2e-158 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HFHCACOH_00740 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HFHCACOH_00741 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HFHCACOH_00742 1.4e-89 ypmB S Protein conserved in bacteria
HFHCACOH_00743 1.2e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HFHCACOH_00744 4.8e-114 dnaD L DnaD domain protein
HFHCACOH_00745 3.3e-112 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFHCACOH_00746 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HFHCACOH_00750 3e-37
HFHCACOH_00751 4.7e-102 S LexA-binding, inner membrane-associated putative hydrolase
HFHCACOH_00752 1.8e-23
HFHCACOH_00753 6.6e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HFHCACOH_00755 4.1e-174
HFHCACOH_00756 1e-147 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HFHCACOH_00757 1.5e-26 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HFHCACOH_00758 1.6e-238 N Uncharacterized conserved protein (DUF2075)
HFHCACOH_00759 4.8e-228 mmuP E amino acid
HFHCACOH_00760 1.1e-184 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HFHCACOH_00761 2.7e-174 amd 3.5.1.47 E Peptidase family M20/M25/M40
HFHCACOH_00762 1.7e-34 amd 3.5.1.47 E Peptidase family M20/M25/M40
HFHCACOH_00763 1.3e-230 steT E amino acid
HFHCACOH_00764 2e-36 pdxH S Pyridoxamine 5'-phosphate oxidase
HFHCACOH_00765 0.0 pepO 3.4.24.71 O Peptidase family M13
HFHCACOH_00766 0.0
HFHCACOH_00767 2.4e-111 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HFHCACOH_00768 2.5e-175
HFHCACOH_00769 2.3e-56 2.1.1.72, 3.1.21.4 L Eco57I restriction-modification methylase
HFHCACOH_00770 1e-34 S acid phosphatase activity
HFHCACOH_00771 6.4e-48 yviA S Protein of unknown function (DUF421)
HFHCACOH_00772 2.8e-159 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFHCACOH_00773 6.3e-163 dnaQ 2.7.7.7 L EXOIII
HFHCACOH_00774 1.2e-157 endA F DNA RNA non-specific endonuclease
HFHCACOH_00775 1.1e-280 pipD E Dipeptidase
HFHCACOH_00776 9.6e-200 malK P ATPases associated with a variety of cellular activities
HFHCACOH_00777 2.6e-155 gtsB P ABC-type sugar transport systems, permease components
HFHCACOH_00778 3.7e-51 gtsC P Binding-protein-dependent transport system inner membrane component
HFHCACOH_00779 6.2e-254 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HFHCACOH_00780 1.4e-234 G Bacterial extracellular solute-binding protein
HFHCACOH_00781 5.3e-159 corA P CorA-like Mg2+ transporter protein
HFHCACOH_00782 3.6e-158 3.5.2.6 V Beta-lactamase enzyme family
HFHCACOH_00783 3.3e-98 yobS K Bacterial regulatory proteins, tetR family
HFHCACOH_00784 0.0 ydgH S MMPL family
HFHCACOH_00785 2.5e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HFHCACOH_00786 4.8e-45 hipB K Helix-turn-helix
HFHCACOH_00787 7.3e-63 hipB K Helix-turn-helix
HFHCACOH_00788 1e-08 hipB K Helix-turn-helix
HFHCACOH_00789 3.4e-154 I alpha/beta hydrolase fold
HFHCACOH_00790 7.5e-109 yjbF S SNARE associated Golgi protein
HFHCACOH_00791 9.2e-98 J Acetyltransferase (GNAT) domain
HFHCACOH_00792 3.4e-252 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFHCACOH_00794 1.8e-261
HFHCACOH_00795 3.3e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFHCACOH_00796 7.3e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HFHCACOH_00797 3e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFHCACOH_00798 8.9e-215 ecsB U ABC transporter
HFHCACOH_00799 3.9e-136 ecsA V ABC transporter, ATP-binding protein
HFHCACOH_00800 3.8e-54 higA K Helix-turn-helix XRE-family like proteins
HFHCACOH_00801 8.9e-80 hit FG Scavenger mRNA decapping enzyme C-term binding
HFHCACOH_00802 1.5e-26
HFHCACOH_00803 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFHCACOH_00804 3.1e-77 S PAS domain
HFHCACOH_00805 1.5e-188 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFHCACOH_00806 0.0 L AAA domain
HFHCACOH_00807 2.4e-231 yhaO L Ser Thr phosphatase family protein
HFHCACOH_00808 9.4e-56 yheA S Belongs to the UPF0342 family
HFHCACOH_00809 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HFHCACOH_00810 6.3e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFHCACOH_00811 1.4e-21 bglH 3.2.1.86 GT1 G beta-glucosidase activity
HFHCACOH_00812 1.9e-09 5.3.3.2 C FMN-dependent dehydrogenase
HFHCACOH_00813 4.5e-135 mgtC S MgtC family
HFHCACOH_00814 1.2e-137 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HFHCACOH_00815 1.2e-78 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCACOH_00816 7.5e-84 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCACOH_00817 1e-34 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCACOH_00818 2.5e-12 K Helix-turn-helix domain, rpiR family
HFHCACOH_00819 2.9e-46 K Helix-turn-helix domain, rpiR family
HFHCACOH_00820 2e-285 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCACOH_00821 3.7e-54
HFHCACOH_00822 4e-150 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HFHCACOH_00823 1.9e-20 UW LPXTG-motif cell wall anchor domain protein
HFHCACOH_00824 2.6e-186 lysC 2.7.2.4 E Belongs to the aspartokinase family
HFHCACOH_00825 7.1e-246 thrC 4.2.3.1 E Threonine synthase
HFHCACOH_00826 1.8e-51 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HFHCACOH_00827 4e-11 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HFHCACOH_00828 1.1e-26 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HFHCACOH_00829 1.8e-40 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HFHCACOH_00830 1.2e-108 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFHCACOH_00831 7.4e-107
HFHCACOH_00832 7.9e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFHCACOH_00833 4.7e-109 S Peptidase family M23
HFHCACOH_00834 2e-152 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HFHCACOH_00835 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HFHCACOH_00836 3.2e-69 yqeY S YqeY-like protein
HFHCACOH_00837 1.5e-175 phoH T phosphate starvation-inducible protein PhoH
HFHCACOH_00838 8.5e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFHCACOH_00839 2.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFHCACOH_00840 6.8e-136 recO L Involved in DNA repair and RecF pathway recombination
HFHCACOH_00841 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HFHCACOH_00842 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HFHCACOH_00843 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFHCACOH_00844 2.3e-196 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFHCACOH_00845 1.5e-123 S Peptidase family M23
HFHCACOH_00846 6e-31 mutT 3.6.1.55 F NUDIX domain
HFHCACOH_00847 1.6e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HFHCACOH_00848 5.9e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFHCACOH_00849 5.8e-241 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HFHCACOH_00850 1.2e-175 yifK E Amino acid permease
HFHCACOH_00851 6.7e-60 yifK E Amino acid permease
HFHCACOH_00852 1.7e-187 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFHCACOH_00853 5.2e-95 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFHCACOH_00854 7.2e-16 ps301 K sequence-specific DNA binding
HFHCACOH_00855 0.0 aha1 P E1-E2 ATPase
HFHCACOH_00856 4.1e-161 metQ1 P Belongs to the nlpA lipoprotein family
HFHCACOH_00857 2.8e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFHCACOH_00858 6.4e-88 metI P ABC transporter permease
HFHCACOH_00859 4.7e-187 S cog cog1373
HFHCACOH_00860 3.2e-33
HFHCACOH_00861 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFHCACOH_00862 1e-262 frdC 1.3.5.4 C FAD binding domain
HFHCACOH_00863 2.8e-19 UW LPXTG-motif cell wall anchor domain protein
HFHCACOH_00864 2.4e-17 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
HFHCACOH_00866 2.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HFHCACOH_00867 2.4e-28 fhaB M Rib/alpha-like repeat
HFHCACOH_00868 7.8e-38 fhaB M Rib/alpha-like repeat
HFHCACOH_00869 3.4e-44
HFHCACOH_00871 5.5e-44
HFHCACOH_00872 7.9e-257 pepC 3.4.22.40 E Peptidase C1-like family
HFHCACOH_00873 2.3e-25 scrB 3.2.1.26 GH32 G invertase
HFHCACOH_00874 1.9e-215 scrA 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFHCACOH_00875 6.2e-63 scrA 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFHCACOH_00876 8.5e-41 rafA 3.2.1.22 G alpha-galactosidase
HFHCACOH_00877 6e-172 rafA 3.2.1.22 G alpha-galactosidase
HFHCACOH_00878 3.7e-70 rafA 3.2.1.22 G alpha-galactosidase
HFHCACOH_00879 1.6e-188 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HFHCACOH_00880 4e-134 manY G PTS system
HFHCACOH_00881 1.7e-173 manN G system, mannose fructose sorbose family IID component
HFHCACOH_00882 7.6e-64 manO S Domain of unknown function (DUF956)
HFHCACOH_00883 1.8e-148 K Transcriptional regulator
HFHCACOH_00884 2.3e-87 maa S transferase hexapeptide repeat
HFHCACOH_00885 7.8e-239 cycA E Amino acid permease
HFHCACOH_00886 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HFHCACOH_00887 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFHCACOH_00888 2.1e-56 yagE E amino acid
HFHCACOH_00889 3.8e-35
HFHCACOH_00890 4.2e-90 UW LPXTG-motif cell wall anchor domain protein
HFHCACOH_00891 1.1e-15 S LPXTG cell wall anchor motif
HFHCACOH_00892 1e-81 S LPXTG cell wall anchor motif
HFHCACOH_00893 1.5e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFHCACOH_00894 3.9e-136 4.1.1.44 S Carboxymuconolactone decarboxylase family
HFHCACOH_00895 6.4e-37
HFHCACOH_00896 7.7e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HFHCACOH_00897 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HFHCACOH_00898 3.1e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HFHCACOH_00899 1.9e-127 XK27_08435 K UTRA
HFHCACOH_00900 7.8e-219 L Belongs to the 'phage' integrase family
HFHCACOH_00901 1.2e-28
HFHCACOH_00902 9.3e-116 repB EP Plasmid replication protein
HFHCACOH_00906 2.1e-66
HFHCACOH_00908 1.4e-195 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HFHCACOH_00909 1.3e-51
HFHCACOH_00911 2.7e-14 D nuclear chromosome segregation
HFHCACOH_00918 9.3e-11 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HFHCACOH_00919 6.8e-53 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HFHCACOH_00920 2.9e-139 S Uncharacterized protein conserved in bacteria (DUF2263)
HFHCACOH_00921 5.1e-60
HFHCACOH_00922 3.1e-54 K Helix-turn-helix domain
HFHCACOH_00923 2.9e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFHCACOH_00924 2.8e-163 ppaC 3.6.1.1 C inorganic pyrophosphatase
HFHCACOH_00925 2.9e-171 K Transcriptional regulator
HFHCACOH_00926 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFHCACOH_00927 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFHCACOH_00928 4.3e-95 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFHCACOH_00929 0.0 snf 2.7.11.1 KL domain protein
HFHCACOH_00930 3.9e-43 snf 2.7.11.1 KL domain protein
HFHCACOH_00931 7.1e-18 snf 2.7.11.1 KL domain protein
HFHCACOH_00932 7.8e-32
HFHCACOH_00933 2.5e-27
HFHCACOH_00934 5.8e-85 dps P Belongs to the Dps family
HFHCACOH_00935 2.6e-94 K acetyltransferase
HFHCACOH_00936 5.2e-164 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HFHCACOH_00937 4.8e-50 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFHCACOH_00938 1.5e-39 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFHCACOH_00939 2.6e-106 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFHCACOH_00940 1.9e-83 K Bacterial regulatory proteins, tetR family
HFHCACOH_00941 9.9e-143 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HFHCACOH_00942 3e-60 S Hydrolases of the alpha beta superfamily
HFHCACOH_00943 3.2e-29 S Hydrolases of the alpha beta superfamily
HFHCACOH_00944 5.2e-57 S Alpha beta hydrolase
HFHCACOH_00945 2.7e-91 K Acetyltransferase (GNAT) family
HFHCACOH_00946 2e-255 gor 1.8.1.7 C Glutathione reductase
HFHCACOH_00947 9.9e-117 L Integrase
HFHCACOH_00949 1.6e-47 dam 2.1.1.72 H Site-specific DNA-methyltransferase (adenine-specific)
HFHCACOH_00950 8.6e-198 L hmm pf00665
HFHCACOH_00951 6.1e-112 L Helix-turn-helix domain
HFHCACOH_00952 2.2e-159 cjaA ET ABC transporter substrate-binding protein
HFHCACOH_00953 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFHCACOH_00954 9.9e-86 P ABC transporter permease
HFHCACOH_00955 1e-111 papP P ABC transporter, permease protein
HFHCACOH_00956 6e-61 adhR K helix_turn_helix, mercury resistance
HFHCACOH_00957 1.4e-98 3.6.1.55, 3.6.1.67 F NUDIX domain
HFHCACOH_00958 1.1e-198 folP 2.5.1.15 H dihydropteroate synthase
HFHCACOH_00959 3.6e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HFHCACOH_00960 3e-201 folE 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 F GTP cyclohydrolase 1
HFHCACOH_00961 6.5e-57 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFHCACOH_00962 5.2e-124 magIII L Base excision DNA repair protein, HhH-GPD family
HFHCACOH_00963 7.2e-43
HFHCACOH_00964 1.6e-76 K LytTr DNA-binding domain
HFHCACOH_00965 4e-53 S Protein of unknown function (DUF3021)
HFHCACOH_00966 9.2e-89 XK27_09675 K Acetyltransferase (GNAT) domain
HFHCACOH_00967 5.8e-132
HFHCACOH_00968 2e-103
HFHCACOH_00969 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HFHCACOH_00970 5.3e-189 V Beta-lactamase
HFHCACOH_00971 1.1e-37 pepV 3.5.1.18 E dipeptidase PepV
HFHCACOH_00972 2.5e-181 pepV 3.5.1.18 E dipeptidase PepV
HFHCACOH_00974 2.8e-61
HFHCACOH_00975 2.1e-96 MA20_25245 K Acetyltransferase (GNAT) domain
HFHCACOH_00980 2.3e-111 emrY EGP Major facilitator Superfamily
HFHCACOH_00981 8.1e-241 pyrP F Permease
HFHCACOH_00982 9.8e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFHCACOH_00983 2.9e-260 emrY EGP Major facilitator Superfamily
HFHCACOH_00984 2.1e-216 mdtG EGP Major facilitator Superfamily
HFHCACOH_00985 5.8e-50 pepA E M42 glutamyl aminopeptidase
HFHCACOH_00986 2.2e-136 pepA E M42 glutamyl aminopeptidase
HFHCACOH_00987 5.8e-310 ybiT S ABC transporter, ATP-binding protein
HFHCACOH_00988 1.2e-143
HFHCACOH_00989 1.4e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HFHCACOH_00990 9.3e-147 glnH ET ABC transporter
HFHCACOH_00991 5.1e-81 K Transcriptional regulator, MarR family
HFHCACOH_00992 1.2e-292 XK27_09600 V ABC transporter, ATP-binding protein
HFHCACOH_00993 0.0 V ABC transporter transmembrane region
HFHCACOH_00994 9.3e-101 S ABC-type cobalt transport system, permease component
HFHCACOH_00995 1.4e-180 EGP Major facilitator superfamily
HFHCACOH_00996 3.1e-113 udk 2.7.1.48 F Zeta toxin
HFHCACOH_00997 2e-85 tlpA2 L Transposase IS200 like
HFHCACOH_00998 9.3e-52 S PFAM Uncharacterised protein family UPF0150
HFHCACOH_01000 1.7e-88 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFHCACOH_01001 3.1e-64 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFHCACOH_01002 5.1e-99 3.6.1.27 I Acid phosphatase homologues
HFHCACOH_01003 2.3e-132 yitS S Uncharacterised protein, DegV family COG1307
HFHCACOH_01004 8.1e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFHCACOH_01005 7.8e-66 S Domain of unknown function (DUF4767)
HFHCACOH_01006 4.6e-85 C nitroreductase
HFHCACOH_01007 7.5e-147 ypbG 2.7.1.2 GK ROK family
HFHCACOH_01008 1.5e-252 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCACOH_01009 4.3e-45 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCACOH_01011 1.4e-70 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCACOH_01012 1.8e-61 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCACOH_01013 8e-134 gmuR K UTRA
HFHCACOH_01014 2.9e-110 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCACOH_01015 1.2e-80 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCACOH_01016 3.1e-36 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCACOH_01017 1.5e-57 S Domain of unknown function (DUF3284)
HFHCACOH_01018 5.5e-16 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFHCACOH_01019 1.7e-157 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFHCACOH_01021 2e-23
HFHCACOH_01022 2.5e-38 gepA K Protein of unknown function (DUF4065)
HFHCACOH_01023 2e-70 S Iron-sulphur cluster biosynthesis
HFHCACOH_01025 1.2e-126 3.6.1.13, 3.6.1.55 F NUDIX domain
HFHCACOH_01026 5.4e-267 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFHCACOH_01027 7.5e-108 pncA Q Isochorismatase family
HFHCACOH_01028 4.8e-17 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HFHCACOH_01029 2.2e-176 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HFHCACOH_01030 3.9e-25 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFHCACOH_01031 2e-29 S Protein of unknown function (DUF3923)
HFHCACOH_01032 7.7e-53
HFHCACOH_01033 2.1e-79 K Acetyltransferase (GNAT) domain
HFHCACOH_01034 7.6e-47
HFHCACOH_01035 6.8e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HFHCACOH_01036 2.9e-47
HFHCACOH_01037 4.7e-41 glcU U sugar transport
HFHCACOH_01038 7.3e-84 glcU U sugar transport
HFHCACOH_01039 1.5e-108 S Domain of unknown function (DUF4411)
HFHCACOH_01040 2.4e-220 E IrrE N-terminal-like domain
HFHCACOH_01041 5.6e-08 yfdK S phosphatase homologous to the C-terminal domain of histone macroH2A1
HFHCACOH_01042 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HFHCACOH_01043 1.9e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HFHCACOH_01044 1.4e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFHCACOH_01045 1.5e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HFHCACOH_01046 3e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFHCACOH_01047 6.5e-165 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFHCACOH_01048 4.3e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFHCACOH_01049 5.7e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFHCACOH_01050 1.2e-20 S RelB antitoxin
HFHCACOH_01052 3.9e-119 S CAAX protease self-immunity
HFHCACOH_01053 2.3e-196 S DUF218 domain
HFHCACOH_01054 1.3e-11 macB_3 V ABC transporter, ATP-binding protein
HFHCACOH_01055 2.8e-180 macB_3 V ABC transporter, ATP-binding protein
HFHCACOH_01056 2.9e-46 macB_3 V ABC transporter, ATP-binding protein
HFHCACOH_01057 1.9e-105 macB_3 V ABC transporter, ATP-binding protein
HFHCACOH_01058 1.4e-17 macB_3 V ABC transporter, ATP-binding protein
HFHCACOH_01059 4.3e-96 S ECF transporter, substrate-specific component
HFHCACOH_01060 2.6e-160 yeaE S Aldo/keto reductase family
HFHCACOH_01061 1.1e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFHCACOH_01062 4e-100 ybbH_2 K rpiR family
HFHCACOH_01063 5e-145 S Bacterial protein of unknown function (DUF871)
HFHCACOH_01064 5.7e-57 yfeW 3.4.16.4 V Beta-lactamase
HFHCACOH_01065 2.6e-55 yfeW 3.4.16.4 V Beta-lactamase
HFHCACOH_01067 1.5e-121 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HFHCACOH_01068 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFHCACOH_01070 5.5e-118 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HFHCACOH_01071 5.3e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HFHCACOH_01072 1.2e-146 cof S haloacid dehalogenase-like hydrolase
HFHCACOH_01073 3.7e-230 pbuG S permease
HFHCACOH_01074 2.2e-174 S cog cog1373
HFHCACOH_01075 2.4e-74
HFHCACOH_01076 5.9e-106 K LysR substrate binding domain
HFHCACOH_01077 2.5e-19
HFHCACOH_01078 2.8e-213 S Sterol carrier protein domain
HFHCACOH_01079 8.4e-96 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HFHCACOH_01080 2.3e-51 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HFHCACOH_01081 1.4e-69 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HFHCACOH_01082 8.5e-145 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFHCACOH_01083 1.1e-12 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFHCACOH_01084 7.1e-90 arcA 3.5.3.6 E Arginine
HFHCACOH_01085 6.6e-15 arcA 3.5.3.6 E Arginine
HFHCACOH_01086 7.1e-22 arcA 3.5.3.6 E Arginine
HFHCACOH_01087 5.1e-156 lysR5 K LysR substrate binding domain
HFHCACOH_01088 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HFHCACOH_01089 2.4e-84 3.4.21.96 S SLAP domain
HFHCACOH_01090 2.7e-253 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFHCACOH_01091 1.6e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HFHCACOH_01092 6.8e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HFHCACOH_01093 2.4e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFHCACOH_01094 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HFHCACOH_01095 3.1e-111 srtA 3.4.22.70 M sortase family
HFHCACOH_01096 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFHCACOH_01097 3.8e-15
HFHCACOH_01098 4.8e-57 pacL 3.6.3.8 P P-type ATPase
HFHCACOH_01099 5.7e-278 pacL 3.6.3.8 P P-type ATPase
HFHCACOH_01100 1.1e-86 pacL 3.6.3.8 P P-type ATPase
HFHCACOH_01101 2.5e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFHCACOH_01102 6.4e-260 epsU S Polysaccharide biosynthesis protein
HFHCACOH_01103 1.7e-136 M Glycosyltransferase sugar-binding region containing DXD motif
HFHCACOH_01104 4e-86 ydcK S Belongs to the SprT family
HFHCACOH_01106 1.3e-103 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HFHCACOH_01107 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HFHCACOH_01108 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFHCACOH_01109 1.5e-206 camS S sex pheromone
HFHCACOH_01110 5.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFHCACOH_01111 4.9e-260 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFHCACOH_01112 9.2e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFHCACOH_01113 3e-170 yegS 2.7.1.107 G Lipid kinase
HFHCACOH_01114 3e-114 S Protein of unknown function (DUF1211)
HFHCACOH_01115 1.1e-119 ybhL S Belongs to the BI1 family
HFHCACOH_01116 5e-54
HFHCACOH_01117 4.6e-67 nhaC C Na H antiporter NhaC
HFHCACOH_01118 5.5e-86 uspA T universal stress protein
HFHCACOH_01120 4.2e-151 phnD P Phosphonate ABC transporter
HFHCACOH_01121 5.2e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HFHCACOH_01122 3.2e-128 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HFHCACOH_01123 6.4e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HFHCACOH_01124 7.8e-108 tag 3.2.2.20 L glycosylase
HFHCACOH_01125 3.3e-83
HFHCACOH_01126 1.3e-273 S Calcineurin-like phosphoesterase
HFHCACOH_01127 0.0 asnB 6.3.5.4 E Asparagine synthase
HFHCACOH_01128 2.8e-254 yxbA 6.3.1.12 S ATP-grasp enzyme
HFHCACOH_01131 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HFHCACOH_01132 9.6e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFHCACOH_01133 7.8e-100 S Iron-sulfur cluster assembly protein
HFHCACOH_01134 2e-230 XK27_04775 S PAS domain
HFHCACOH_01135 5.7e-225 yttB EGP Major facilitator Superfamily
HFHCACOH_01136 0.0 pepO 3.4.24.71 O Peptidase family M13
HFHCACOH_01137 4.6e-59 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFHCACOH_01138 2.6e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HFHCACOH_01139 1.9e-132 cobQ S glutamine amidotransferase
HFHCACOH_01140 1.1e-81 M NlpC/P60 family
HFHCACOH_01141 7.3e-164 EG EamA-like transporter family
HFHCACOH_01142 2.7e-109
HFHCACOH_01143 6.2e-77
HFHCACOH_01144 2.8e-174 XK27_05540 S DUF218 domain
HFHCACOH_01145 2.3e-90 yheS_2 S ATPases associated with a variety of cellular activities
HFHCACOH_01146 1.3e-74 yheS_2 S ATPases associated with a variety of cellular activities
HFHCACOH_01147 8.6e-84
HFHCACOH_01148 3e-57
HFHCACOH_01149 1.5e-244 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFHCACOH_01150 5.6e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFHCACOH_01151 7.7e-180 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFHCACOH_01153 9e-203 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HFHCACOH_01154 2.6e-191 asnA 6.3.1.1 F aspartate--ammonia ligase
HFHCACOH_01155 4.9e-106 steT_1 E amino acid
HFHCACOH_01156 1.5e-14 puuD S peptidase C26
HFHCACOH_01157 4.3e-244 purD 6.3.4.13 F Belongs to the GARS family
HFHCACOH_01158 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HFHCACOH_01159 4.9e-201 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HFHCACOH_01160 1.6e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFHCACOH_01161 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFHCACOH_01162 3.3e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFHCACOH_01163 1.3e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFHCACOH_01164 8.7e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HFHCACOH_01165 9.7e-219 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFHCACOH_01166 1.3e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFHCACOH_01167 0.0 lacS G Transporter
HFHCACOH_01168 5.1e-109 lacS G Transporter
HFHCACOH_01169 6.8e-48 lacS G Transporter
HFHCACOH_01170 2.1e-24 lacS G Transporter
HFHCACOH_01171 1.2e-188 lacR K Transcriptional regulator
HFHCACOH_01172 2.3e-41 L hmm pf00665
HFHCACOH_01173 1.9e-172 K helix_turn_helix, arabinose operon control protein
HFHCACOH_01174 3.3e-250 cbiO1 S ABC transporter, ATP-binding protein
HFHCACOH_01175 1.4e-92 P Cobalt transport protein
HFHCACOH_01176 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HFHCACOH_01177 1.1e-30 higA K Helix-turn-helix XRE-family like proteins
HFHCACOH_01178 3e-29
HFHCACOH_01179 2.5e-81 V ABC transporter
HFHCACOH_01181 8.8e-25 K Helix-turn-helix XRE-family like proteins
HFHCACOH_01182 1.5e-38 K Helix-turn-helix XRE-family like proteins
HFHCACOH_01183 2.8e-90 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFHCACOH_01184 4.3e-180 htrA 3.4.21.107 O serine protease
HFHCACOH_01185 4.3e-149 vicX 3.1.26.11 S domain protein
HFHCACOH_01186 7.7e-149 yycI S YycH protein
HFHCACOH_01187 2.2e-241 yycH S YycH protein
HFHCACOH_01188 1e-305 vicK 2.7.13.3 T Histidine kinase
HFHCACOH_01189 2.2e-131 K response regulator
HFHCACOH_01190 1e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HFHCACOH_01191 1.4e-17 K Helix-turn-helix
HFHCACOH_01192 2.9e-105 K DNA-binding helix-turn-helix protein
HFHCACOH_01193 2.4e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFHCACOH_01194 1.1e-223 pbuX F xanthine permease
HFHCACOH_01195 9e-158 msmR K AraC-like ligand binding domain
HFHCACOH_01196 4.8e-284 pipD E Dipeptidase
HFHCACOH_01197 4.4e-49 S Haloacid dehalogenase-like hydrolase
HFHCACOH_01198 3.7e-33 S Haloacid dehalogenase-like hydrolase
HFHCACOH_01199 4.8e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFHCACOH_01200 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFHCACOH_01201 2.2e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFHCACOH_01202 1.8e-66 S Domain of unknown function (DUF1934)
HFHCACOH_01203 1.8e-267 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFHCACOH_01204 1e-41
HFHCACOH_01205 2.9e-70 GK ROK family
HFHCACOH_01206 7.4e-38 GK ROK family
HFHCACOH_01208 2.3e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFHCACOH_01209 4.7e-194 S SLAP domain
HFHCACOH_01210 1.1e-121
HFHCACOH_01211 5e-105 S SLAP domain
HFHCACOH_01212 1.4e-208 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFHCACOH_01213 3.2e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HFHCACOH_01214 3.2e-37 veg S Biofilm formation stimulator VEG
HFHCACOH_01215 9.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFHCACOH_01216 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFHCACOH_01217 1.3e-147 tatD L hydrolase, TatD family
HFHCACOH_01218 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFHCACOH_01219 8.3e-205 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HFHCACOH_01220 2.2e-266 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HFHCACOH_01221 5.1e-108 S TPM domain
HFHCACOH_01222 5.5e-91 comEB 3.5.4.12 F MafB19-like deaminase
HFHCACOH_01223 1.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFHCACOH_01224 4.5e-114 E Belongs to the SOS response-associated peptidase family
HFHCACOH_01226 4.9e-114
HFHCACOH_01227 4.5e-74 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFHCACOH_01228 2.9e-67 hsp O Belongs to the small heat shock protein (HSP20) family
HFHCACOH_01229 4.4e-255 pepC 3.4.22.40 E aminopeptidase
HFHCACOH_01230 2.7e-174 oppF P Belongs to the ABC transporter superfamily
HFHCACOH_01231 1.3e-201 oppD P Belongs to the ABC transporter superfamily
HFHCACOH_01232 4.9e-185 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFHCACOH_01233 2.9e-144 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFHCACOH_01234 8.3e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFHCACOH_01235 7.9e-299 oppA E ABC transporter, substratebinding protein
HFHCACOH_01236 9.4e-300 oppA E ABC transporter, substratebinding protein
HFHCACOH_01237 3.3e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFHCACOH_01238 1.9e-175 prmA J Ribosomal protein L11 methyltransferase
HFHCACOH_01239 1.2e-58
HFHCACOH_01240 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFHCACOH_01241 5.6e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFHCACOH_01242 3.1e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HFHCACOH_01243 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HFHCACOH_01244 7.5e-222 patA 2.6.1.1 E Aminotransferase
HFHCACOH_01245 2.7e-219 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFHCACOH_01246 1.9e-104 S reductase
HFHCACOH_01247 1e-31 S reductase
HFHCACOH_01248 5.3e-21 yxeH S hydrolase
HFHCACOH_01249 6.2e-41 yxeH S hydrolase
HFHCACOH_01250 9.6e-46 yxeH S hydrolase
HFHCACOH_01251 1.1e-15 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFHCACOH_01252 2.6e-75 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFHCACOH_01253 3.3e-43 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFHCACOH_01254 7.6e-250 yfnA E Amino Acid
HFHCACOH_01255 6.2e-108 dedA 3.1.3.1 S SNARE associated Golgi protein
HFHCACOH_01256 1.3e-68 M Glycosyltransferase sugar-binding region containing DXD motif
HFHCACOH_01257 1.1e-42 M Glycosyltransferase like family 2
HFHCACOH_01258 1.2e-65 MA20_17390 GT4 M Glycosyl transferases group 1
HFHCACOH_01259 1.8e-164 M Glycosyl transferases group 1
HFHCACOH_01260 2.2e-122 rfbP M Bacterial sugar transferase
HFHCACOH_01261 3.3e-146 ywqE 3.1.3.48 GM PHP domain protein
HFHCACOH_01262 5.3e-118 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HFHCACOH_01263 8.3e-141 epsB M biosynthesis protein
HFHCACOH_01264 6.3e-180 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HFHCACOH_01265 2.2e-18 S Predicted membrane protein (DUF2335)
HFHCACOH_01267 2.5e-199 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFHCACOH_01268 2.9e-190 S Cysteine-rich secretory protein family
HFHCACOH_01270 1.9e-140 M NlpC/P60 family
HFHCACOH_01271 4.6e-160 degV S EDD domain protein, DegV family
HFHCACOH_01272 7.7e-65
HFHCACOH_01273 0.0 FbpA K Fibronectin-binding protein
HFHCACOH_01274 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HFHCACOH_01275 8.8e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HFHCACOH_01276 8.5e-157 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFHCACOH_01277 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFHCACOH_01278 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HFHCACOH_01279 2.8e-34
HFHCACOH_01280 7.6e-70 cpdA S Calcineurin-like phosphoesterase
HFHCACOH_01281 7.9e-82 cpdA S Calcineurin-like phosphoesterase
HFHCACOH_01282 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HFHCACOH_01283 8e-70 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFHCACOH_01284 9.5e-106 ypsA S Belongs to the UPF0398 family
HFHCACOH_01285 1.3e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFHCACOH_01288 1.5e-288 lsa S ABC transporter
HFHCACOH_01289 1.5e-17
HFHCACOH_01290 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFHCACOH_01291 2.5e-74 S Protein of unknown function (DUF3021)
HFHCACOH_01292 1.5e-74 K LytTr DNA-binding domain
HFHCACOH_01293 1.1e-102 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
HFHCACOH_01296 0.0 uvrA3 L excinuclease ABC, A subunit
HFHCACOH_01297 6.8e-95 yyaR K Acetyltransferase (GNAT) domain
HFHCACOH_01298 3e-38 mta K helix_turn_helix, mercury resistance
HFHCACOH_01299 2.2e-63 mta K helix_turn_helix, mercury resistance
HFHCACOH_01301 3.1e-22 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HFHCACOH_01302 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HFHCACOH_01306 2.7e-96 D Alpha beta
HFHCACOH_01307 3.9e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFHCACOH_01308 9.6e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
HFHCACOH_01309 1.9e-86
HFHCACOH_01310 1.3e-73
HFHCACOH_01311 7.3e-158 hlyX S Transporter associated domain
HFHCACOH_01312 3.2e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HFHCACOH_01313 3.9e-44 XK27_09445 S Domain of unknown function (DUF1827)
HFHCACOH_01314 0.0 clpE O Belongs to the ClpA ClpB family
HFHCACOH_01315 2.4e-26
HFHCACOH_01316 5.5e-40 ptsH G phosphocarrier protein HPR
HFHCACOH_01317 1.9e-306 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFHCACOH_01318 8.4e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFHCACOH_01319 1.9e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFHCACOH_01320 6.1e-28 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
HFHCACOH_01321 1.5e-46 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
HFHCACOH_01322 8.9e-104 E Amino acid permease
HFHCACOH_01323 2.9e-66 E Amino acid permease
HFHCACOH_01324 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HFHCACOH_01325 7.6e-64 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HFHCACOH_01326 2.5e-247 ynbB 4.4.1.1 P aluminum resistance
HFHCACOH_01327 3.4e-89 ktrA P domain protein
HFHCACOH_01328 2.7e-178 ktrB P Potassium uptake protein
HFHCACOH_01329 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HFHCACOH_01330 1.7e-78 C Flavodoxin
HFHCACOH_01331 2e-112 3.6.1.27 I Acid phosphatase homologues
HFHCACOH_01332 2.3e-105 lacA 2.3.1.79 S Transferase hexapeptide repeat
HFHCACOH_01333 2.2e-207 pbpX1 V Beta-lactamase
HFHCACOH_01334 9.2e-150 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HFHCACOH_01335 6.9e-93 S ECF-type riboflavin transporter, S component
HFHCACOH_01336 3.9e-176 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HFHCACOH_01337 3.8e-78 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFHCACOH_01338 3.6e-79 marR K Transcriptional regulator
HFHCACOH_01339 2.9e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFHCACOH_01340 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFHCACOH_01341 3.7e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HFHCACOH_01342 8.6e-128 IQ reductase
HFHCACOH_01343 9.5e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFHCACOH_01344 1.8e-78 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFHCACOH_01345 2e-73 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HFHCACOH_01346 2.1e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HFHCACOH_01347 3.5e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFHCACOH_01348 3.4e-143 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HFHCACOH_01349 1.1e-133 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HFHCACOH_01350 5.3e-189 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFHCACOH_01351 3.3e-26 bioY S BioY family
HFHCACOH_01352 5.9e-101
HFHCACOH_01353 7.1e-33 S Protein of unknown function (DUF1211)
HFHCACOH_01354 0.0 kup P Transport of potassium into the cell
HFHCACOH_01355 4e-72
HFHCACOH_01357 3.5e-29
HFHCACOH_01358 2e-37 S Protein of unknown function (DUF2922)
HFHCACOH_01359 5e-206 S SLAP domain
HFHCACOH_01361 3.2e-12 K DNA-templated transcription, initiation
HFHCACOH_01362 7.1e-26 K DNA-templated transcription, initiation
HFHCACOH_01363 5.1e-63
HFHCACOH_01364 1.6e-222 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFHCACOH_01365 2e-205 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HFHCACOH_01366 0.0 yjbQ P TrkA C-terminal domain protein
HFHCACOH_01367 7.6e-91 gepA K Protein of unknown function (DUF4065)
HFHCACOH_01368 7.5e-83 S Oxidoreductase family, NAD-binding Rossmann fold
HFHCACOH_01369 6e-134
HFHCACOH_01370 6.1e-208 EGP Major facilitator Superfamily
HFHCACOH_01371 5.9e-103
HFHCACOH_01372 4.3e-106 S Fic/DOC family
HFHCACOH_01373 2.4e-56
HFHCACOH_01374 2.1e-89
HFHCACOH_01375 4.4e-47 ypaA S Protein of unknown function (DUF1304)
HFHCACOH_01376 5.6e-66 S Putative adhesin
HFHCACOH_01377 3e-295 V ABC-type multidrug transport system, ATPase and permease components
HFHCACOH_01378 9.9e-294 P ABC transporter
HFHCACOH_01379 3.7e-60
HFHCACOH_01380 1.4e-29 fic D Fic/DOC family
HFHCACOH_01381 6.5e-34
HFHCACOH_01382 5.2e-253 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HFHCACOH_01383 5.1e-235 mepA V MATE efflux family protein
HFHCACOH_01384 8.1e-232 S Putative peptidoglycan binding domain
HFHCACOH_01385 6.3e-92 epsB M biosynthesis protein
HFHCACOH_01386 1.1e-20 ywqE 3.1.3.48 GM PHP domain protein
HFHCACOH_01387 3.9e-119 rfbP M Bacterial sugar transferase
HFHCACOH_01388 5.6e-206 M Glycosyl transferases group 1
HFHCACOH_01389 1.4e-152 epsE GT2 M Glycosyltransferase like family 2
HFHCACOH_01390 6.7e-188 S EpsG family
HFHCACOH_01391 3.5e-134 M Glycosyltransferase sugar-binding region containing DXD motif
HFHCACOH_01392 1.1e-231 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFHCACOH_01393 1.8e-74 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase-like
HFHCACOH_01394 4.7e-185 2.1.1.21, 6.3.5.4 E Asparagine synthase
HFHCACOH_01395 1.6e-231 cps4J S Polysaccharide biosynthesis protein
HFHCACOH_01396 5.5e-16 atzC 3.5.4.1 F cytosine deaminase
HFHCACOH_01397 2.6e-146 D CobQ CobB MinD ParA nucleotide binding domain protein
HFHCACOH_01399 9.4e-69 K Helix-turn-helix XRE-family like proteins
HFHCACOH_01400 2e-141 K Helix-turn-helix XRE-family like proteins
HFHCACOH_01401 3.9e-107 S Protein of unknown function (DUF3232)
HFHCACOH_01402 5.4e-56 S SLAP domain
HFHCACOH_01403 2.4e-32
HFHCACOH_01404 7.3e-62 K Helix-turn-helix XRE-family like proteins
HFHCACOH_01405 1.2e-88 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HFHCACOH_01406 1.9e-33 S Protein of unknown function (DUF3232)
HFHCACOH_01407 5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFHCACOH_01408 8.4e-218 iscS2 2.8.1.7 E Aminotransferase class V
HFHCACOH_01409 2.3e-280 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFHCACOH_01410 1.8e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFHCACOH_01411 2.7e-82 yueI S Protein of unknown function (DUF1694)
HFHCACOH_01412 5.5e-242 rarA L recombination factor protein RarA
HFHCACOH_01413 2.5e-35
HFHCACOH_01414 1.2e-77 usp6 T universal stress protein
HFHCACOH_01415 2.1e-216 rodA D Belongs to the SEDS family
HFHCACOH_01416 3.3e-33 S Protein of unknown function (DUF2969)
HFHCACOH_01417 3.8e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HFHCACOH_01418 7.2e-178 mbl D Cell shape determining protein MreB Mrl
HFHCACOH_01419 3.4e-30 ywzB S Protein of unknown function (DUF1146)
HFHCACOH_01420 2.2e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HFHCACOH_01421 8.7e-233 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFHCACOH_01422 6e-169 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFHCACOH_01423 2.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFHCACOH_01424 6.8e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFHCACOH_01425 3e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFHCACOH_01426 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFHCACOH_01427 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HFHCACOH_01428 8.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFHCACOH_01429 5.4e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFHCACOH_01430 1e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFHCACOH_01431 6.9e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFHCACOH_01432 7.6e-114 tdk 2.7.1.21 F thymidine kinase
HFHCACOH_01433 1.8e-248 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HFHCACOH_01436 4.6e-196 ampC V Beta-lactamase
HFHCACOH_01437 3.1e-41 EGP Major facilitator Superfamily
HFHCACOH_01438 2.3e-80 EGP Major facilitator Superfamily
HFHCACOH_01439 6.5e-32 EGP Major facilitator Superfamily
HFHCACOH_01440 2.7e-20 EGP Major facilitator Superfamily
HFHCACOH_01441 3e-259 pgi 5.3.1.9 G Belongs to the GPI family
HFHCACOH_01442 3.2e-107 vanZ V VanZ like family
HFHCACOH_01443 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFHCACOH_01444 5.7e-272 yclK 2.7.13.3 T Histidine kinase
HFHCACOH_01445 4.1e-130 K Transcriptional regulatory protein, C terminal
HFHCACOH_01446 9.2e-60 S SdpI/YhfL protein family
HFHCACOH_01447 6.6e-168 manA 5.3.1.8 G mannose-6-phosphate isomerase
HFHCACOH_01448 2.1e-224 patB 4.4.1.8 E Aminotransferase, class I
HFHCACOH_01449 2e-30 M Protein of unknown function (DUF3737)
HFHCACOH_01450 2.4e-34 M Protein of unknown function (DUF3737)
HFHCACOH_01452 6.8e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFHCACOH_01453 1.1e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HFHCACOH_01454 4.2e-81 comGF U Putative Competence protein ComGF
HFHCACOH_01455 5e-41
HFHCACOH_01456 2.1e-73
HFHCACOH_01457 3.7e-44 comGC U competence protein ComGC
HFHCACOH_01458 9e-176 comGB NU type II secretion system
HFHCACOH_01459 5.1e-159 comGA NU Type II IV secretion system protein
HFHCACOH_01460 8.9e-133 yebC K Transcriptional regulatory protein
HFHCACOH_01461 3e-90 S VanZ like family
HFHCACOH_01462 1.1e-40 S HicB_like antitoxin of bacterial toxin-antitoxin system
HFHCACOH_01463 4.3e-29 S Fic/DOC family
HFHCACOH_01464 2e-10 S Fic/DOC family
HFHCACOH_01465 1.4e-231 yrvN L AAA C-terminal domain
HFHCACOH_01466 3.9e-143 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HFHCACOH_01467 2.2e-34 K Acetyltransferase (GNAT) family
HFHCACOH_01468 6.3e-11 K Acetyltransferase (GNAT) family
HFHCACOH_01469 8.7e-34 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HFHCACOH_01470 3.5e-58 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HFHCACOH_01471 1.7e-88 dps P Belongs to the Dps family
HFHCACOH_01472 6e-35 copZ C Heavy-metal-associated domain
HFHCACOH_01473 4.6e-29 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HFHCACOH_01474 3.2e-287 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HFHCACOH_01475 9.5e-101 L Bifunctional protein
HFHCACOH_01476 2.1e-121 K Transcriptional regulator
HFHCACOH_01477 3.6e-260 npr 1.11.1.1 C NADH oxidase
HFHCACOH_01478 5.3e-68 S pyridoxamine 5-phosphate
HFHCACOH_01479 4e-170 yobV1 K WYL domain
HFHCACOH_01480 7.1e-31 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
HFHCACOH_01481 6.8e-14
HFHCACOH_01482 7.7e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HFHCACOH_01483 3e-90 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HFHCACOH_01484 4.3e-169 xerC D Phage integrase, N-terminal SAM-like domain
HFHCACOH_01485 9.4e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HFHCACOH_01486 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFHCACOH_01487 1.1e-155 dprA LU DNA protecting protein DprA
HFHCACOH_01488 1.1e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFHCACOH_01489 1.7e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFHCACOH_01490 7.3e-262 yjcE P Sodium proton antiporter
HFHCACOH_01491 9.3e-36 yozE S Belongs to the UPF0346 family
HFHCACOH_01492 9.4e-147 DegV S Uncharacterised protein, DegV family COG1307
HFHCACOH_01493 1.1e-113 hlyIII S protein, hemolysin III
HFHCACOH_01494 1.7e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HFHCACOH_01495 2.4e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HFHCACOH_01496 3.3e-222 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HFHCACOH_01498 4.6e-62 psiE S Phosphate-starvation-inducible E
HFHCACOH_01499 3.5e-183 Q Imidazolonepropionase and related amidohydrolases
HFHCACOH_01500 5.2e-23 Q Imidazolonepropionase and related amidohydrolases
HFHCACOH_01501 1e-129 oppA E ABC transporter
HFHCACOH_01502 1.8e-56 oppA E ABC transporter
HFHCACOH_01503 1.7e-55 oppA E ABC transporter
HFHCACOH_01504 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HFHCACOH_01505 1e-218 naiP EGP Major facilitator Superfamily
HFHCACOH_01506 6.2e-236 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFHCACOH_01507 4.5e-130 znuB U ABC 3 transport family
HFHCACOH_01508 1.6e-117 fhuC P ABC transporter
HFHCACOH_01509 4.4e-158 psaA P Belongs to the bacterial solute-binding protein 9 family
HFHCACOH_01510 1e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
HFHCACOH_01511 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HFHCACOH_01512 2.4e-167 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HFHCACOH_01513 5.2e-136 fruR K DeoR C terminal sensor domain
HFHCACOH_01516 8.7e-27
HFHCACOH_01517 2.7e-32
HFHCACOH_01518 6.6e-34 yozG K Transcriptional regulator
HFHCACOH_01519 1.4e-53 S Enterocin A Immunity
HFHCACOH_01520 8.8e-15 S Enterocin A Immunity
HFHCACOH_01521 3.2e-28 S Archaea bacterial proteins of unknown function
HFHCACOH_01522 1.9e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFHCACOH_01523 5.4e-78 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFHCACOH_01524 2.3e-309 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HFHCACOH_01525 7.5e-123 darA C Flavodoxin
HFHCACOH_01526 4.8e-141 qmcA O prohibitin homologues
HFHCACOH_01527 4.3e-52 L RelB antitoxin
HFHCACOH_01528 3.1e-14
HFHCACOH_01529 4.9e-195 S Bacteriocin helveticin-J
HFHCACOH_01530 2.2e-290 M Peptidase family M1 domain
HFHCACOH_01531 2.3e-176 S SLAP domain
HFHCACOH_01532 2.5e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HFHCACOH_01533 2.4e-55 S Psort location Cytoplasmic, score
HFHCACOH_01534 5e-56 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HFHCACOH_01535 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HFHCACOH_01536 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFHCACOH_01537 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFHCACOH_01538 2e-81 S Short repeat of unknown function (DUF308)
HFHCACOH_01539 1.4e-164 rapZ S Displays ATPase and GTPase activities
HFHCACOH_01540 4.4e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HFHCACOH_01541 1.1e-170 whiA K May be required for sporulation
HFHCACOH_01542 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFHCACOH_01544 1.6e-42 repA S Replication initiator protein A
HFHCACOH_01546 4.6e-219 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HFHCACOH_01547 4.9e-52 3.6.1.55 F NUDIX domain
HFHCACOH_01548 1.9e-09 rpiR1 K Helix-turn-helix domain, rpiR family
HFHCACOH_01549 1.6e-63 rpiR1 K Helix-turn-helix domain, rpiR family
HFHCACOH_01550 2.4e-75 S Alpha/beta hydrolase family
HFHCACOH_01551 7.8e-20
HFHCACOH_01552 5.3e-195 O Heat shock 70 kDa protein
HFHCACOH_01553 6.1e-42
HFHCACOH_01554 1.9e-57
HFHCACOH_01555 7.5e-169 pbpX1 V Beta-lactamase
HFHCACOH_01556 2.6e-52 3.6.1.55 F NUDIX domain
HFHCACOH_01557 2.8e-40 3.6.1.55 F NUDIX domain
HFHCACOH_01558 7.1e-300 I Protein of unknown function (DUF2974)
HFHCACOH_01559 3.2e-28 C FMN_bind
HFHCACOH_01560 3.9e-82
HFHCACOH_01561 1.7e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HFHCACOH_01562 4.2e-153 S Aldo keto reductase
HFHCACOH_01563 4.6e-227 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCACOH_01564 1.6e-22 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCACOH_01565 2.2e-63 K UTRA domain
HFHCACOH_01566 7e-33 K UTRA domain
HFHCACOH_01568 1.4e-07 S Bacteriocin helveticin-J
HFHCACOH_01571 4.8e-151 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HFHCACOH_01572 1.5e-115 dedA S SNARE-like domain protein
HFHCACOH_01573 2.9e-84 S Protein of unknown function (DUF1461)
HFHCACOH_01574 3.2e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFHCACOH_01575 3.3e-88 yutD S Protein of unknown function (DUF1027)
HFHCACOH_01576 4e-275 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HFHCACOH_01577 1.1e-55
HFHCACOH_01578 2.8e-128 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HFHCACOH_01579 3.8e-99 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HFHCACOH_01580 2.7e-180 ccpA K catabolite control protein A
HFHCACOH_01581 6.3e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HFHCACOH_01582 1e-44
HFHCACOH_01583 3.3e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFHCACOH_01584 8.2e-154 ykuT M mechanosensitive ion channel
HFHCACOH_01585 2.3e-122 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HFHCACOH_01586 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFHCACOH_01587 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFHCACOH_01588 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFHCACOH_01589 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HFHCACOH_01590 2e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFHCACOH_01591 1.9e-104 rplD J Forms part of the polypeptide exit tunnel
HFHCACOH_01592 5.3e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFHCACOH_01593 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFHCACOH_01594 9.3e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFHCACOH_01595 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFHCACOH_01596 8.8e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFHCACOH_01597 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFHCACOH_01598 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HFHCACOH_01599 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFHCACOH_01600 1.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFHCACOH_01601 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFHCACOH_01602 7.9e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFHCACOH_01603 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFHCACOH_01604 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFHCACOH_01605 2.1e-91 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFHCACOH_01606 3.7e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFHCACOH_01607 1.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFHCACOH_01608 6.6e-24 rpmD J Ribosomal protein L30
HFHCACOH_01609 1.5e-71 rplO J Binds to the 23S rRNA
HFHCACOH_01610 4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFHCACOH_01611 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFHCACOH_01612 2.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFHCACOH_01613 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HFHCACOH_01614 3.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFHCACOH_01615 5.2e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFHCACOH_01616 8.1e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFHCACOH_01617 5.3e-60 rplQ J Ribosomal protein L17
HFHCACOH_01618 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFHCACOH_01619 2.8e-151 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFHCACOH_01620 5.1e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFHCACOH_01621 5.1e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFHCACOH_01622 2.2e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFHCACOH_01623 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
HFHCACOH_01624 4.2e-71 S Protein of unknown function (DUF805)
HFHCACOH_01625 1e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HFHCACOH_01626 3.9e-111 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HFHCACOH_01627 1.9e-133 S membrane transporter protein
HFHCACOH_01628 2.6e-126 pgm3 G Belongs to the phosphoglycerate mutase family
HFHCACOH_01629 7.8e-163 czcD P cation diffusion facilitator family transporter
HFHCACOH_01630 5.5e-23
HFHCACOH_01631 4.1e-124 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFHCACOH_01632 1.6e-182 S AAA domain
HFHCACOH_01633 1.8e-104 L transposase, IS605 OrfB family
HFHCACOH_01634 2.1e-114 L transposase, IS605 OrfB family
HFHCACOH_01635 0.0 mgtA 3.6.3.2, 3.6.3.6 P COG0474 Cation transport ATPase
HFHCACOH_01636 1.2e-08
HFHCACOH_01637 3.1e-145 glcU U sugar transport
HFHCACOH_01638 5.3e-264 pepC 3.4.22.40 E Peptidase C1-like family
HFHCACOH_01639 5.5e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFHCACOH_01640 1.9e-109 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HFHCACOH_01641 1.7e-99 G Aldose 1-epimerase
HFHCACOH_01642 1.1e-201 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HFHCACOH_01643 2.5e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFHCACOH_01644 0.0 XK27_08315 M Sulfatase
HFHCACOH_01645 8.4e-265 S Fibronectin type III domain
HFHCACOH_01646 9.7e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFHCACOH_01647 2e-20
HFHCACOH_01648 1.7e-07 S ACT domain
HFHCACOH_01649 4.5e-94
HFHCACOH_01650 1.5e-89
HFHCACOH_01651 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFHCACOH_01652 2.9e-165 dnaI L Primosomal protein DnaI
HFHCACOH_01653 5.8e-247 dnaB L Replication initiation and membrane attachment
HFHCACOH_01654 4.1e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFHCACOH_01655 4.6e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFHCACOH_01656 1.2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFHCACOH_01657 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFHCACOH_01658 5.5e-97 yxkA S Phosphatidylethanolamine-binding protein
HFHCACOH_01659 5.8e-247 yjjP S Putative threonine/serine exporter
HFHCACOH_01660 7e-44 citR K Putative sugar-binding domain
HFHCACOH_01661 1.8e-50 citR K Putative sugar-binding domain
HFHCACOH_01662 4.9e-54
HFHCACOH_01663 3e-15
HFHCACOH_01664 2.2e-66 S Domain of unknown function DUF1828
HFHCACOH_01665 6.9e-93 S UPF0397 protein
HFHCACOH_01666 0.0 ykoD P ABC transporter, ATP-binding protein
HFHCACOH_01667 1.5e-139 cbiQ P cobalt transport
HFHCACOH_01668 2.7e-10
HFHCACOH_01669 2.7e-71 yeaL S Protein of unknown function (DUF441)
HFHCACOH_01670 2.4e-73 M1-431 S Protein of unknown function (DUF1706)
HFHCACOH_01671 9.1e-27 G Belongs to the glycosyl hydrolase family 6
HFHCACOH_01672 2e-124
HFHCACOH_01673 1.4e-268 hsdM 2.1.1.72 V type I restriction-modification system
HFHCACOH_01674 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
HFHCACOH_01675 2.5e-227 S response to antibiotic
HFHCACOH_01676 1.3e-90
HFHCACOH_01677 1.5e-107
HFHCACOH_01679 5e-83
HFHCACOH_01680 2.9e-50
HFHCACOH_01682 4.7e-58 mobC S Bacterial mobilisation protein (MobC)
HFHCACOH_01683 3.2e-199 D Relaxase/Mobilisation nuclease domain
HFHCACOH_01684 3.4e-109
HFHCACOH_01685 3.4e-62 XK27_09990 D Fic/DOC family
HFHCACOH_01687 1.5e-182 L Lactococcus lactis RepB C-terminus
HFHCACOH_01689 1.8e-50 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HFHCACOH_01690 1.7e-38 S Antitoxin component of a toxin-antitoxin (TA) module
HFHCACOH_01691 3.1e-104 L Integrase
HFHCACOH_01694 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFHCACOH_01695 2.4e-150 glnH ET ABC transporter substrate-binding protein
HFHCACOH_01696 2.5e-107 gluC P ABC transporter permease
HFHCACOH_01697 1.6e-101 glnP P ABC transporter permease
HFHCACOH_01698 1.4e-46 S Protein of unknown function (DUF2974)
HFHCACOH_01699 9.5e-84 S Protein of unknown function (DUF2974)
HFHCACOH_01700 1.6e-46 K sequence-specific DNA binding
HFHCACOH_01701 2.6e-166 S SLAP domain
HFHCACOH_01702 8.5e-53 S Bacteriocin helveticin-J
HFHCACOH_01703 1.7e-235 G Bacterial extracellular solute-binding protein
HFHCACOH_01704 3.8e-161 2.7.7.12 C Domain of unknown function (DUF4931)
HFHCACOH_01705 2.3e-42 hprA 1.1.1.29 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFHCACOH_01706 2.7e-63 1.6.5.2 S NADPH-dependent FMN reductase
HFHCACOH_01707 1.6e-27 2.7.7.7 K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFHCACOH_01708 1e-97 KL SNF2 family N-terminal domain
HFHCACOH_01710 5e-69 D COG0419 ATPase involved in DNA repair
HFHCACOH_01712 2.1e-23 tnp2PF3 L Transposase
HFHCACOH_01713 4.7e-103 S haloacid dehalogenase-like hydrolase
HFHCACOH_01714 1.9e-113 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HFHCACOH_01715 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
HFHCACOH_01716 2e-92
HFHCACOH_01717 8.1e-22 S Small integral membrane protein (DUF2273)
HFHCACOH_01718 5.9e-73 S cog cog1302
HFHCACOH_01719 1.3e-11 S Transglycosylase associated protein
HFHCACOH_01720 3.8e-16
HFHCACOH_01721 1e-22 IQ Enoyl-(Acyl carrier protein) reductase
HFHCACOH_01722 2.9e-43
HFHCACOH_01723 4.4e-10 S Small integral membrane protein (DUF2273)
HFHCACOH_01724 2.3e-58 S protein conserved in bacteria
HFHCACOH_01726 1.9e-118 scrR K Transcriptional regulator, LacI family
HFHCACOH_01727 1.9e-122 liaI S membrane
HFHCACOH_01728 4.3e-77 XK27_02470 K LytTr DNA-binding domain
HFHCACOH_01729 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFHCACOH_01730 0.0 uup S ABC transporter, ATP-binding protein
HFHCACOH_01731 1.4e-12 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HFHCACOH_01732 8.7e-97 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HFHCACOH_01733 1.9e-106 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HFHCACOH_01734 1.3e-26 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HFHCACOH_01735 2.2e-114 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HFHCACOH_01736 2e-107 yfdE 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HFHCACOH_01737 3.7e-111 yfdE 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HFHCACOH_01738 1.9e-08 S Toxin ToxN, type III toxin-antitoxin system
HFHCACOH_01739 3.9e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HFHCACOH_01740 1.1e-67 rplI J Binds to the 23S rRNA
HFHCACOH_01741 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HFHCACOH_01742 1.6e-37 S SLAP domain
HFHCACOH_01743 2e-70 S SLAP domain
HFHCACOH_01746 2.5e-20 KLT serine threonine protein kinase
HFHCACOH_01747 1.3e-173 V ABC transporter transmembrane region
HFHCACOH_01750 2.7e-168 psaA P Belongs to the bacterial solute-binding protein 9 family
HFHCACOH_01752 1.1e-215 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFHCACOH_01753 3e-257 qacA EGP Major facilitator Superfamily
HFHCACOH_01754 1.3e-27 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFHCACOH_01755 9e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFHCACOH_01756 1.3e-119 3.6.1.27 I Acid phosphatase homologues
HFHCACOH_01757 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFHCACOH_01758 6e-278 ytgP S Polysaccharide biosynthesis protein
HFHCACOH_01759 4.9e-182 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HFHCACOH_01760 3e-91 dhaL 2.7.1.121 S Dak2
HFHCACOH_01761 1.3e-55 dhaM 2.7.1.121 S PTS system fructose IIA component
HFHCACOH_01762 3.9e-26
HFHCACOH_01763 2.4e-221 O Belongs to the peptidase S8 family
HFHCACOH_01764 1.3e-93 O Belongs to the peptidase S8 family
HFHCACOH_01765 3.6e-63 O Belongs to the peptidase S8 family
HFHCACOH_01766 5.1e-72 infB UW LPXTG-motif cell wall anchor domain protein
HFHCACOH_01767 6.9e-40 UW LPXTG-motif cell wall anchor domain protein
HFHCACOH_01768 1.1e-21 UW LPXTG-motif cell wall anchor domain protein
HFHCACOH_01770 2.2e-58 CO Thioredoxin
HFHCACOH_01771 8e-117 M1-798 K Rhodanese Homology Domain
HFHCACOH_01772 4.1e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFHCACOH_01773 1.7e-10 frnE Q DSBA-like thioredoxin domain
HFHCACOH_01774 1.2e-18 frnE Q DSBA-like thioredoxin domain
HFHCACOH_01775 1.7e-29 frnE Q DSBA-like thioredoxin domain
HFHCACOH_01776 7.4e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HFHCACOH_01777 1e-31 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
HFHCACOH_01778 2e-49 pspC KT PspC domain
HFHCACOH_01780 6.4e-243 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HFHCACOH_01781 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFHCACOH_01782 4.4e-110 M ErfK YbiS YcfS YnhG
HFHCACOH_01783 3.3e-89 padR K Virulence activator alpha C-term
HFHCACOH_01784 2e-102 padC Q Phenolic acid decarboxylase
HFHCACOH_01785 6.1e-111 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HFHCACOH_01786 2.2e-12 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HFHCACOH_01787 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HFHCACOH_01788 3.5e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HFHCACOH_01789 1.2e-91 3.6.1.55 L NUDIX domain
HFHCACOH_01790 2.1e-39
HFHCACOH_01791 2.8e-24
HFHCACOH_01792 8.7e-70 S SNARE associated Golgi protein
HFHCACOH_01793 3.6e-22 S SNARE associated Golgi protein
HFHCACOH_01794 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HFHCACOH_01795 5e-170 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFHCACOH_01796 3.5e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFHCACOH_01797 2.1e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
HFHCACOH_01798 1.1e-110 yjbK S CYTH
HFHCACOH_01799 2.5e-112 yjbH Q Thioredoxin
HFHCACOH_01800 1.5e-158 coiA 3.6.4.12 S Competence protein
HFHCACOH_01801 8.2e-134 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HFHCACOH_01802 5.1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFHCACOH_01803 4.8e-221 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HFHCACOH_01804 4.2e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
HFHCACOH_01805 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFHCACOH_01806 2.3e-29 secG U Preprotein translocase
HFHCACOH_01807 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFHCACOH_01808 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HFHCACOH_01809 2e-80 S Threonine/Serine exporter, ThrE
HFHCACOH_01810 6.7e-139 thrE S Putative threonine/serine exporter
HFHCACOH_01811 3.1e-292 S ABC transporter
HFHCACOH_01812 1e-55
HFHCACOH_01813 6.4e-99 rimL J Acetyltransferase (GNAT) domain
HFHCACOH_01814 3.2e-87 S Protein of unknown function (DUF554)
HFHCACOH_01815 4.3e-11 S Protein of unknown function (DUF554)
HFHCACOH_01816 3e-213 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HFHCACOH_01817 0.0 pepF E oligoendopeptidase F
HFHCACOH_01818 9.1e-42 Z012_06740 S Fic/DOC family
HFHCACOH_01819 5.7e-92 3.6.3.8 P P-type ATPase
HFHCACOH_01820 4.8e-132 3.6.3.8 P P-type ATPase
HFHCACOH_01821 3.2e-75 3.6.3.8 P P-type ATPase
HFHCACOH_01822 3.2e-15
HFHCACOH_01823 9.2e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
HFHCACOH_01824 8.7e-38 glvR K Helix-turn-helix domain, rpiR family
HFHCACOH_01825 2e-81 3.6.1.13 L Belongs to the Nudix hydrolase family
HFHCACOH_01826 7.2e-47 sugE U Multidrug resistance protein
HFHCACOH_01827 5.1e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFHCACOH_01828 2.4e-206 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HFHCACOH_01829 1.5e-115 G phosphoglycerate mutase
HFHCACOH_01830 1.2e-144 K SIS domain
HFHCACOH_01831 4.7e-166 yufQ S Belongs to the binding-protein-dependent transport system permease family
HFHCACOH_01832 1e-199 yufP S Belongs to the binding-protein-dependent transport system permease family
HFHCACOH_01833 6.2e-285 xylG 3.6.3.17 S ABC transporter
HFHCACOH_01834 1.4e-190 tcsA S ABC transporter substrate-binding protein PnrA-like
HFHCACOH_01836 6.8e-154 V ABC transporter transmembrane region
HFHCACOH_01837 5.1e-290 V ABC-type multidrug transport system, ATPase and permease components
HFHCACOH_01838 3.7e-285 V ABC-type multidrug transport system, ATPase and permease components
HFHCACOH_01840 4.8e-15 L PFAM IS66 Orf2 family protein
HFHCACOH_01841 1.2e-08
HFHCACOH_01842 1.5e-14 S Phage derived protein Gp49-like (DUF891)
HFHCACOH_01843 1.5e-40 K Helix-turn-helix XRE-family like proteins
HFHCACOH_01844 5.3e-43
HFHCACOH_01845 1.9e-54 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HFHCACOH_01846 2.5e-242 L Probable transposase
HFHCACOH_01847 4.9e-12 L Resolvase, N terminal domain
HFHCACOH_01848 2.2e-57 L Resolvase, N terminal domain
HFHCACOH_01849 1.1e-30
HFHCACOH_01850 4.5e-71 S HIRAN
HFHCACOH_01851 4.2e-56 oppA E ABC transporter substrate-binding protein
HFHCACOH_01852 9e-140 cjaA ET ABC transporter substrate-binding protein
HFHCACOH_01853 4.8e-118 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFHCACOH_01854 2.3e-87 P ABC transporter permease
HFHCACOH_01855 2.4e-105 papP P ABC transporter, permease protein
HFHCACOH_01856 1e-102 S PFAM Archaeal ATPase
HFHCACOH_01857 7.7e-219 S SLAP domain
HFHCACOH_01859 1.9e-143 mrr L restriction endonuclease
HFHCACOH_01860 1.1e-47 V Beta-lactamase
HFHCACOH_01861 3.5e-123
HFHCACOH_01862 1.6e-238 S response to antibiotic
HFHCACOH_01863 1.1e-126 pgm3 G Phosphoglycerate mutase family
HFHCACOH_01864 4.9e-125 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HFHCACOH_01865 0.0 helD 3.6.4.12 L DNA helicase
HFHCACOH_01866 8.5e-41 V ATPases associated with a variety of cellular activities
HFHCACOH_01867 2.8e-197 V Protein of unknown function DUF262
HFHCACOH_01868 2.9e-37 2.1.1.72 S Adenine-specific methyltransferase EcoRI
HFHCACOH_01870 8.3e-120 yhiD S MgtC family
HFHCACOH_01871 7.5e-241 I Protein of unknown function (DUF2974)
HFHCACOH_01872 1.4e-35
HFHCACOH_01874 1.1e-80 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HFHCACOH_01875 1.1e-74 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HFHCACOH_01876 9.2e-175 degV S DegV family
HFHCACOH_01877 1.4e-162 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HFHCACOH_01878 5.2e-34 S CHY zinc finger
HFHCACOH_01879 8.7e-29 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFHCACOH_01880 3.1e-56 tnp2PF3 L Transposase DDE domain
HFHCACOH_01881 5e-28 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HFHCACOH_01882 1e-180 nifS 2.8.1.7 E DegT/DnrJ/EryC1/StrS aminotransferase family
HFHCACOH_01883 4.3e-200 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HFHCACOH_01884 1e-268 nadB 1.3.5.4, 1.4.3.16 H L-aspartate oxidase
HFHCACOH_01885 5e-66 4.4.1.5 E Glyoxalase
HFHCACOH_01886 1.7e-78 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HFHCACOH_01887 8.4e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFHCACOH_01888 9.9e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HFHCACOH_01889 1.1e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HFHCACOH_01890 2.2e-85 S ECF transporter, substrate-specific component
HFHCACOH_01891 8.9e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
HFHCACOH_01892 5.7e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFHCACOH_01893 4.5e-58 yabA L Involved in initiation control of chromosome replication
HFHCACOH_01894 2.2e-154 holB 2.7.7.7 L DNA polymerase III
HFHCACOH_01895 1.9e-50 yaaQ S Cyclic-di-AMP receptor
HFHCACOH_01896 1.9e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFHCACOH_01897 2.6e-33 S Protein of unknown function (DUF2508)
HFHCACOH_01898 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFHCACOH_01899 2.5e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFHCACOH_01900 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFHCACOH_01901 6.9e-92 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFHCACOH_01902 7.7e-117 rsmC 2.1.1.172 J Methyltransferase
HFHCACOH_01903 1.4e-83 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HFHCACOH_01904 1.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFHCACOH_01905 3.5e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFHCACOH_01906 9.6e-156 yfdV S Membrane transport protein
HFHCACOH_01907 4.1e-10 yfdV S Membrane transport protein
HFHCACOH_01908 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
HFHCACOH_01909 7.8e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFHCACOH_01910 7.9e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFHCACOH_01911 2e-155 pstA P Phosphate transport system permease protein PstA
HFHCACOH_01912 5.4e-173 pstC P probably responsible for the translocation of the substrate across the membrane
HFHCACOH_01913 4e-156 pstS P Phosphate
HFHCACOH_01914 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFHCACOH_01915 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFHCACOH_01916 6.9e-101 nusG K Participates in transcription elongation, termination and antitermination
HFHCACOH_01917 5.9e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFHCACOH_01918 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFHCACOH_01919 3.3e-283 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HFHCACOH_01920 2.2e-34
HFHCACOH_01921 2.7e-94 sigH K Belongs to the sigma-70 factor family
HFHCACOH_01922 7.8e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFHCACOH_01923 6.7e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFHCACOH_01924 3.5e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFHCACOH_01925 2.4e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFHCACOH_01926 2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFHCACOH_01927 9.5e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HFHCACOH_01928 4.5e-54
HFHCACOH_01929 5.6e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFHCACOH_01930 1.3e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFHCACOH_01931 0.0 kup P Transport of potassium into the cell
HFHCACOH_01932 4.8e-176 rihB 3.2.2.1 F Nucleoside
HFHCACOH_01933 1.4e-130 gntR K UbiC transcription regulator-associated domain protein
HFHCACOH_01934 3.7e-17 ropB K Helix-turn-helix domain
HFHCACOH_01935 4e-61 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HFHCACOH_01936 1.8e-37 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HFHCACOH_01937 1.9e-152 S hydrolase
HFHCACOH_01938 1.5e-95 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
HFHCACOH_01939 1.1e-182 P secondary active sulfate transmembrane transporter activity
HFHCACOH_01940 3.3e-121 L Transposase and inactivated derivatives, IS30 family
HFHCACOH_01941 7.1e-164 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
HFHCACOH_01942 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HFHCACOH_01943 4.3e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFHCACOH_01945 1.3e-105 L Phage integrase family
HFHCACOH_01946 1.6e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HFHCACOH_01947 1.3e-81 1.6.5.2 S Flavodoxin-like fold
HFHCACOH_01948 1.3e-40 K Bacterial regulatory proteins, tetR family
HFHCACOH_01949 3.3e-51
HFHCACOH_01950 3.9e-44 relB L Addiction module antitoxin, RelB DinJ family
HFHCACOH_01951 4.1e-84
HFHCACOH_01952 2.6e-40
HFHCACOH_01953 1.3e-23
HFHCACOH_01954 7.6e-70 S Iron-sulphur cluster biosynthesis
HFHCACOH_01955 7.1e-32
HFHCACOH_01956 2.1e-67
HFHCACOH_01957 2.9e-27 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HFHCACOH_01958 5.8e-49 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HFHCACOH_01959 6e-24 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HFHCACOH_01960 5.6e-13
HFHCACOH_01961 8.9e-58 M LysM domain protein
HFHCACOH_01962 8.2e-188 D nuclear chromosome segregation
HFHCACOH_01963 6.4e-110 G Phosphoglycerate mutase family
HFHCACOH_01964 5.2e-201 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HFHCACOH_01965 4.4e-129 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HFHCACOH_01966 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFHCACOH_01967 1.2e-73 nrdI F Probably involved in ribonucleotide reductase function
HFHCACOH_01968 8.1e-193 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFHCACOH_01969 3.1e-42 IQ reductase
HFHCACOH_01970 3.6e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HFHCACOH_01971 4.5e-219 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HFHCACOH_01972 1.5e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HFHCACOH_01973 1.9e-27
HFHCACOH_01974 6.3e-53 4.4.1.5 E lactoylglutathione lyase activity
HFHCACOH_01975 1.6e-66 S ASCH domain
HFHCACOH_01976 2e-108 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFHCACOH_01978 1.8e-80
HFHCACOH_01979 3.9e-303
HFHCACOH_01980 2.8e-282 lsa S ABC transporter
HFHCACOH_01981 1.2e-100
HFHCACOH_01982 1.1e-106 vraA 6.2.1.3 IQ acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HFHCACOH_01983 1.8e-140 vraB 2.3.1.9 I Belongs to the thiolase family
HFHCACOH_01986 5.4e-72 IQ KR domain
HFHCACOH_01987 1.2e-83 fabK 1.3.1.9 C Nitronate monooxygenase
HFHCACOH_01988 1.4e-190 L Psort location Cytoplasmic, score
HFHCACOH_01989 7.9e-29
HFHCACOH_01990 1.5e-107 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HFHCACOH_01991 8e-192 KQ helix_turn_helix, mercury resistance
HFHCACOH_01992 2.8e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFHCACOH_01993 1.8e-159 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HFHCACOH_01994 1.4e-115 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HFHCACOH_01995 2.8e-190 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFHCACOH_01997 4.4e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HFHCACOH_01998 1.9e-17 brnQ E Component of the transport system for branched-chain amino acids
HFHCACOH_01999 2.7e-100 K LysR substrate binding domain
HFHCACOH_02000 5.9e-109 K Transcriptional regulator, LysR family
HFHCACOH_02001 2.5e-166 arbZ I Phosphate acyltransferases
HFHCACOH_02002 1.4e-157 arbY M Glycosyl transferase family 8
HFHCACOH_02003 5.9e-185 arbY M Glycosyl transferase family 8
HFHCACOH_02004 1.7e-143 arbx M Glycosyl transferase family 8
HFHCACOH_02005 6.9e-128 arbV 2.3.1.51 I Acyl-transferase
HFHCACOH_02007 1.8e-19 pfoS S Phosphotransferase system, EIIC
HFHCACOH_02008 9e-113 pfoS S Phosphotransferase system, EIIC
HFHCACOH_02009 7.4e-254 slpX S SLAP domain
HFHCACOH_02010 8.9e-51
HFHCACOH_02011 3.7e-31
HFHCACOH_02014 1.6e-210
HFHCACOH_02015 5.6e-124 gntR1 K UTRA
HFHCACOH_02016 1.8e-55 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HFHCACOH_02017 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFHCACOH_02018 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFHCACOH_02019 8.4e-81 yebR 1.8.4.14 T GAF domain-containing protein
HFHCACOH_02021 1.6e-08
HFHCACOH_02022 3.3e-28
HFHCACOH_02024 1.1e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HFHCACOH_02025 1.1e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFHCACOH_02026 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFHCACOH_02027 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFHCACOH_02028 4.9e-240 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFHCACOH_02029 4.1e-62 yabR J S1 RNA binding domain
HFHCACOH_02030 3.4e-59 divIC D Septum formation initiator
HFHCACOH_02031 1.8e-34 yabO J S4 domain protein
HFHCACOH_02032 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFHCACOH_02033 1.5e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFHCACOH_02034 8.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HFHCACOH_02035 5.4e-127 S (CBS) domain
HFHCACOH_02036 4.1e-50 K transcriptional regulator
HFHCACOH_02037 4.1e-23 K transcriptional regulator
HFHCACOH_02038 7.6e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFHCACOH_02039 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFHCACOH_02040 5.2e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFHCACOH_02041 5.9e-263 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFHCACOH_02042 1.6e-38 rpmE2 J Ribosomal protein L31
HFHCACOH_02043 4.2e-155 S Sucrose-6F-phosphate phosphohydrolase
HFHCACOH_02044 3.4e-49 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFHCACOH_02045 6.4e-290 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HFHCACOH_02046 5.3e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HFHCACOH_02047 9.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
HFHCACOH_02048 6.3e-196 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HFHCACOH_02049 5.8e-154 ydjP I Alpha/beta hydrolase family
HFHCACOH_02050 5.7e-272 P Sodium:sulfate symporter transmembrane region
HFHCACOH_02051 7.3e-73 S CRISPR-associated protein (Cas_Csn2)
HFHCACOH_02052 1.3e-40 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFHCACOH_02053 9.1e-135 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFHCACOH_02054 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HFHCACOH_02055 2e-288 lsa S ABC transporter
HFHCACOH_02056 0.0 2.7.7.73, 2.7.7.80 H ThiF family
HFHCACOH_02057 4.7e-288 V ABC transporter transmembrane region
HFHCACOH_02058 6.1e-179 S Putative peptidoglycan binding domain
HFHCACOH_02059 1.8e-24
HFHCACOH_02060 6.5e-214 dtpT U amino acid peptide transporter
HFHCACOH_02061 0.0 pepN 3.4.11.2 E aminopeptidase
HFHCACOH_02062 2.5e-59 lysM M LysM domain
HFHCACOH_02063 3.5e-69 S Putative adhesin
HFHCACOH_02064 4.5e-110 V ABC transporter transmembrane region
HFHCACOH_02065 6.7e-129 V ABC transporter transmembrane region
HFHCACOH_02066 1.6e-47 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HFHCACOH_02067 1.5e-49 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HFHCACOH_02068 1.2e-203 napA P Sodium/hydrogen exchanger family
HFHCACOH_02069 0.0 cadA P P-type ATPase
HFHCACOH_02070 1.6e-67
HFHCACOH_02071 1.5e-07
HFHCACOH_02072 4e-11 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFHCACOH_02073 5.7e-74 nrdI F Belongs to the NrdI family
HFHCACOH_02074 2.8e-95
HFHCACOH_02075 1.1e-278 S O-antigen ligase like membrane protein
HFHCACOH_02076 7.4e-25
HFHCACOH_02077 4.6e-92 gmk2 2.7.4.8 F Guanylate kinase homologues.
HFHCACOH_02078 3.1e-93 M NlpC/P60 family
HFHCACOH_02079 2.1e-31 S Archaea bacterial proteins of unknown function
HFHCACOH_02080 1.4e-09
HFHCACOH_02081 1.9e-61 bcgIB 2.1.1.72, 3.1.21.3 L Type I restriction modification DNA specificity domain
HFHCACOH_02082 3.9e-273 V Type I restriction-modification system methyltransferase subunit()
HFHCACOH_02084 0.0 O Belongs to the peptidase S8 family
HFHCACOH_02085 5.7e-146
HFHCACOH_02086 1.4e-164
HFHCACOH_02087 3.8e-136
HFHCACOH_02088 1.7e-262 glnA 6.3.1.2 E glutamine synthetase
HFHCACOH_02089 2.4e-64 ynbB 4.4.1.1 P aluminum resistance
HFHCACOH_02090 8.6e-42 ynbB 4.4.1.1 P aluminum resistance
HFHCACOH_02091 7.6e-205 xerS L Belongs to the 'phage' integrase family
HFHCACOH_02092 9e-67
HFHCACOH_02093 9.1e-89 adk 2.7.4.3 F topology modulation protein
HFHCACOH_02094 1.7e-108 XK27_00160 S Domain of unknown function (DUF5052)
HFHCACOH_02095 2.6e-53
HFHCACOH_02096 8.2e-28 M Glycosyl hydrolases family 25
HFHCACOH_02097 9e-17 M Glycosyl hydrolases family 25
HFHCACOH_02098 4e-76 M Glycosyl hydrolases family 25
HFHCACOH_02099 3.4e-24 lysA2 M Glycosyl hydrolases family 25

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)