| ORF_ID | e_value | Gene_name | EC_number | CAZy | COGs | Description |
|---|---|---|---|---|---|---|
| HFHCACOH_00001 | 6e-200 | dnaJ | O | ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins | ||
| HFHCACOH_00002 | 0.0 | dnaK | O | Heat shock 70 kDa protein | ||
| HFHCACOH_00003 | 1e-78 | grpE | O | Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ | ||
| HFHCACOH_00004 | 2.2e-185 | hrcA | K | Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons | ||
| HFHCACOH_00005 | 8.9e-181 | ribF | 2.7.1.26, 2.7.7.2 | H | Belongs to the ribF family | |
| HFHCACOH_00006 | 1.3e-165 | truB | 5.4.99.25 | J | Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs | |
| HFHCACOH_00007 | 3.3e-59 | rbfA | J | One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA | ||
| HFHCACOH_00008 | 0.0 | infB | J | One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | ||
| HFHCACOH_00009 | 1e-45 | rplGA | J | ribosomal protein | ||
| HFHCACOH_00010 | 1.5e-46 | ylxR | K | Protein of unknown function (DUF448) | ||
| HFHCACOH_00011 | 6.6e-194 | nusA | K | Participates in both transcription termination and antitermination | ||
| HFHCACOH_00012 | 5.5e-83 | rimP | J | Required for maturation of 30S ribosomal subunits | ||
| HFHCACOH_00013 | 0.0 | polC | 2.7.7.7 | L | Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity | |
| HFHCACOH_00014 | 0.0 | proS | 6.1.1.15 | J | Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS | |
| HFHCACOH_00015 | 2.6e-196 | rseP | 3.4.21.107, 3.4.21.116 | M | zinc metalloprotease | |
| HFHCACOH_00016 | 3e-145 | cdsA | 2.7.7.41 | I | Belongs to the CDS family | |
| HFHCACOH_00017 | 5.4e-138 | uppS | 2.5.1.31 | H | Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids | |
| HFHCACOH_00018 | 9.9e-92 | frr | J | Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another | ||
| HFHCACOH_00019 | 7e-130 | pyrH | 2.7.4.22 | F | Catalyzes the reversible phosphorylation of UMP to UDP | |
| HFHCACOH_00020 | 1.1e-184 | tsf | J | Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome | ||
| HFHCACOH_00021 | 1.2e-140 | rpsB | J | Belongs to the universal ribosomal protein uS2 family | ||
| HFHCACOH_00022 | 2.3e-198 | yabB | 2.1.1.223 | L | Methyltransferase small domain | |
| HFHCACOH_00023 | 5.1e-113 | plsC | 2.3.1.51 | I | Acyltransferase | |
| HFHCACOH_00024 | 2.9e-226 | cfa | 2.1.1.317, 2.1.1.79 | M | cyclopropane-fatty-acyl-phospholipid synthase | |
| HFHCACOH_00025 | 0.0 | pepO | 3.4.24.71 | O | Peptidase family M13 | |
| HFHCACOH_00026 | 1.2e-300 | mdlB | V | ABC transporter | ||
| HFHCACOH_00027 | 1.4e-296 | mdlA | V | ABC transporter | ||
| HFHCACOH_00028 | 4.2e-30 | yneF | S | Uncharacterised protein family (UPF0154) | ||
| HFHCACOH_00029 | 4.4e-112 | lexA | 3.4.21.88 | K | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | |
| HFHCACOH_00030 | 2.1e-148 | E | GDSL-like Lipase/Acylhydrolase family | |||
| HFHCACOH_00031 | 9.2e-121 | ung2 | 3.2.2.27 | L | Uracil-DNA glycosylase | |
| HFHCACOH_00032 | 1.1e-56 | rplS | J | This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site | ||
| HFHCACOH_00033 | 1.7e-136 | trmD | 2.1.1.228, 4.6.1.12 | J | Belongs to the RNA methyltransferase TrmD family | |
| HFHCACOH_00034 | 2.4e-92 | rimM | J | An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes | ||
| HFHCACOH_00035 | 4.5e-45 | rpsP | J | Belongs to the bacterial ribosomal protein bS16 family | ||
| HFHCACOH_00036 | 2.9e-228 | ffh | 3.6.5.4 | U | Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY | |
| HFHCACOH_00037 | 3.2e-56 | ylxM | S | Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein | ||
| HFHCACOH_00038 | 3.2e-192 | L | Transposase and inactivated derivatives, IS30 family | |||
| HFHCACOH_00039 | 9.2e-259 | yfnA | E | amino acid | ||
| HFHCACOH_00040 | 7.2e-12 | |||||
| HFHCACOH_00041 | 1.7e-289 | pipD | E | Dipeptidase | ||
| HFHCACOH_00042 | 1.3e-166 | ftsY | U | Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) | ||
| HFHCACOH_00043 | 0.0 | smc | D | Required for chromosome condensation and partitioning | ||
| HFHCACOH_00044 | 1.3e-125 | rnc | 3.1.26.3 | J | Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism | |
| HFHCACOH_00045 | 1.5e-25 | oppA | E | ABC transporter substrate-binding protein | ||
| HFHCACOH_00046 | 1.7e-81 | oppA | E | ABC transporter substrate-binding protein | ||
| HFHCACOH_00047 | 2.4e-28 | oppA | E | ABC transporter substrate-binding protein | ||
| HFHCACOH_00048 | 0.0 | oppA | E | ABC transporter substrate-binding protein | ||
| HFHCACOH_00049 | 5.2e-146 | oppC | P | Binding-protein-dependent transport system inner membrane component | ||
| HFHCACOH_00050 | 5e-176 | oppB | P | ABC transporter permease | ||
| HFHCACOH_00051 | 5.3e-181 | oppF | P | Belongs to the ABC transporter superfamily | ||
| HFHCACOH_00052 | 3.4e-194 | oppD | P | Belongs to the ABC transporter superfamily | ||
| HFHCACOH_00053 | 2.2e-35 | acpP | IQ | Carrier of the growing fatty acid chain in fatty acid biosynthesis | ||
| HFHCACOH_00054 | 2.1e-180 | plsX | 2.3.1.15 | I | Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA | |
| HFHCACOH_00055 | 0.0 | recG | 3.6.4.12 | L | Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) | |
| HFHCACOH_00056 | 1.7e-304 | yloV | S | DAK2 domain fusion protein YloV | ||
| HFHCACOH_00057 | 1.5e-56 | asp | S | Asp23 family, cell envelope-related function | ||
| HFHCACOH_00058 | 9.2e-26 | rpmB | J | Belongs to the bacterial ribosomal protein bL28 family | ||
| HFHCACOH_00059 | 3.1e-30 | |||||
| HFHCACOH_00060 | 1.4e-124 | thiN | 2.7.6.2 | H | thiamine pyrophosphokinase | |
| HFHCACOH_00061 | 9.4e-118 | rpe | 5.1.3.1 | G | Belongs to the ribulose-phosphate 3-epimerase family | |
| HFHCACOH_00062 | 4.4e-166 | rsgA | 3.1.3.100 | S | One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit | |
| HFHCACOH_00063 | 0.0 | prkC | 2.7.11.1 | KLT | serine threonine protein kinase | |
| HFHCACOH_00064 | 3.5e-146 | stp | 3.1.3.16 | T | phosphatase | |
| HFHCACOH_00065 | 1.9e-245 | sun | 2.1.1.176 | J | Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA | |
| HFHCACOH_00066 | 1.4e-170 | fmt | 2.1.2.9 | J | Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus | |
| HFHCACOH_00067 | 0.0 | priA | L | Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA | ||
| HFHCACOH_00068 | 6.5e-34 | rpoZ | 2.7.7.6 | K | Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits | |
| HFHCACOH_00069 | 4.3e-112 | gmk | 2.7.4.8, 4.1.1.23 | F | Essential for recycling GMP and indirectly, cGMP | |
| HFHCACOH_00070 | 6.5e-78 | 6.3.3.2 | S | ASCH | ||
| HFHCACOH_00071 | 6.9e-306 | recN | L | May be involved in recombinational repair of damaged DNA | ||
| HFHCACOH_00072 | 2.8e-151 | rrmJ | 2.1.1.226, 2.1.1.227 | J | Ribosomal RNA large subunit methyltransferase J | |
| HFHCACOH_00073 | 7e-161 | ispA | 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 | H | Belongs to the FPP GGPP synthase family | |
| HFHCACOH_00074 | 2.9e-35 | xseB | 3.1.11.6 | L | Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides | |
| HFHCACOH_00075 | 1.1e-175 | xseA | 3.1.11.6 | L | Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides | |
| HFHCACOH_00076 | 3.1e-101 | folD | 1.5.1.5, 3.5.4.9 | F | Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate | |
| HFHCACOH_00077 | 4e-63 | nusB | K | Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons | ||
| HFHCACOH_00078 | 2.4e-69 | yqhY | S | Asp23 family, cell envelope-related function | ||
| HFHCACOH_00079 | 1.1e-101 | efp | J | Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase | ||
| HFHCACOH_00080 | 8.9e-201 | pepP | 3.4.11.9, 3.4.13.9 | E | Creatinase/Prolidase N-terminal domain | |
| HFHCACOH_00081 | 2.3e-47 | rpmA | J | Belongs to the bacterial ribosomal protein bL27 family | ||
| HFHCACOH_00082 | 5.8e-49 | rplU | J | This protein binds to 23S rRNA in the presence of protein L20 | ||
| HFHCACOH_00083 | 1e-254 | S | Uncharacterized protein conserved in bacteria (DUF2325) | |||
| HFHCACOH_00084 | 1.5e-199 | ilvE | 2.6.1.42 | E | Branched-chain amino acid aminotransferase | |
| HFHCACOH_00085 | 9.5e-129 | S | Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) | |||
| HFHCACOH_00086 | 2.1e-27 | dmpI | 5.3.2.6 | G | Belongs to the 4-oxalocrotonate tautomerase family | |
| HFHCACOH_00087 | 0.0 | S | Predicted membrane protein (DUF2207) | |||
| HFHCACOH_00088 | 5e-213 | M | Glycosyl hydrolases family 25 | |||
| HFHCACOH_00090 | 2.1e-49 | scrR | K | Transcriptional regulator, LacI family | ||
| HFHCACOH_00091 | 5.5e-107 | scrA | 2.7.1.208, 2.7.1.211, 5.3.1.1 | G | phosphotransferase system | |
| HFHCACOH_00092 | 7.9e-48 | |||||
| HFHCACOH_00093 | 3.3e-89 | |||||
| HFHCACOH_00094 | 1.7e-70 | |||||
| HFHCACOH_00096 | 3.2e-34 | |||||
| HFHCACOH_00099 | 1.1e-23 | |||||
| HFHCACOH_00100 | 2.3e-28 | |||||
| HFHCACOH_00101 | 8.5e-17 | K | Transcriptional regulator | |||
| HFHCACOH_00102 | 4.8e-157 | sip | L | Belongs to the 'phage' integrase family | ||
| HFHCACOH_00103 | 3e-44 | groS | O | Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter | ||
| HFHCACOH_00104 | 2e-289 | groL | O | Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions |
Showing 1 to 100 of 1,958 entries
eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)