ORF_ID e_value Gene_name EC_number CAZy COGs Description
IOBPCOKE_00001 5.4e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
IOBPCOKE_00002 3.1e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
IOBPCOKE_00003 9.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
IOBPCOKE_00004 2.5e-197 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IOBPCOKE_00005 5.3e-155 ydjP I Alpha/beta hydrolase family
IOBPCOKE_00006 3.6e-274 P Sodium:sulfate symporter transmembrane region
IOBPCOKE_00007 2.7e-257 pepC 3.4.22.40 E Peptidase C1-like family
IOBPCOKE_00008 2.7e-54
IOBPCOKE_00009 4.9e-77 fhaB M Rib/alpha-like repeat
IOBPCOKE_00010 1.3e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IOBPCOKE_00012 3.3e-38 UW LPXTG-motif cell wall anchor domain protein
IOBPCOKE_00013 3.5e-09 UW LPXTG-motif cell wall anchor domain protein
IOBPCOKE_00014 1.5e-15 S YSIRK type signal peptide
IOBPCOKE_00015 2.1e-130 S YSIRK type signal peptide
IOBPCOKE_00016 6.2e-13 M domain protein
IOBPCOKE_00018 1.5e-57 M domain protein
IOBPCOKE_00020 2.7e-263 frdC 1.3.5.4 C FAD binding domain
IOBPCOKE_00021 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IOBPCOKE_00022 2.9e-59 S cog cog1373
IOBPCOKE_00023 4.9e-92 S cog cog1373
IOBPCOKE_00024 2.9e-88 metI P ABC transporter permease
IOBPCOKE_00025 2.1e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOBPCOKE_00026 5.7e-163 metQ1 P Belongs to the nlpA lipoprotein family
IOBPCOKE_00027 0.0 aha1 P E1-E2 ATPase
IOBPCOKE_00028 2.8e-15 ps301 K sequence-specific DNA binding
IOBPCOKE_00029 6.2e-96 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IOBPCOKE_00030 6.7e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOBPCOKE_00031 9e-251 yifK E Amino acid permease
IOBPCOKE_00032 2.2e-63 S PFAM Uncharacterised protein family UPF0150
IOBPCOKE_00033 3.3e-13
IOBPCOKE_00035 4.1e-127 M hydrolase, family 25
IOBPCOKE_00036 3.2e-53 S Bacteriophage holin of superfamily 6 (Holin_LLH)
IOBPCOKE_00040 8.2e-13
IOBPCOKE_00041 6e-27
IOBPCOKE_00045 0.0 S Phage minor structural protein
IOBPCOKE_00046 2.2e-87 S phage tail
IOBPCOKE_00047 2.1e-150 D NLP P60 protein
IOBPCOKE_00048 2.3e-13 xkdO D NLP P60 protein
IOBPCOKE_00049 1.6e-28 S Bacteriophage Gp15 protein
IOBPCOKE_00050 1.3e-33
IOBPCOKE_00051 4.2e-86 N domain, Protein
IOBPCOKE_00052 1.1e-34 S Minor capsid protein from bacteriophage
IOBPCOKE_00053 4.1e-41 S Minor capsid protein
IOBPCOKE_00054 7.8e-34 S Minor capsid protein
IOBPCOKE_00055 1.5e-33
IOBPCOKE_00056 1.9e-168 gpG
IOBPCOKE_00057 5.6e-58 S Phage minor structural protein GP20
IOBPCOKE_00058 6e-230 S Phage portal protein, SPP1 Gp6-like
IOBPCOKE_00059 5.5e-215 S Terminase RNAseH like domain
IOBPCOKE_00060 1.9e-89 L transposase activity
IOBPCOKE_00062 9.6e-100 K Belongs to the N(4) N(6)-methyltransferase family
IOBPCOKE_00065 1e-103 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
IOBPCOKE_00066 2.7e-51 S ASCH domain
IOBPCOKE_00071 3.6e-20 K transcriptional
IOBPCOKE_00072 1.2e-57 S Single-strand binding protein family
IOBPCOKE_00074 1.3e-57 S IstB-like ATP binding protein
IOBPCOKE_00075 6.8e-41 S calcium ion binding
IOBPCOKE_00076 1.6e-56 S ERF superfamily
IOBPCOKE_00080 1.6e-09
IOBPCOKE_00082 1.1e-24 K Cro/C1-type HTH DNA-binding domain
IOBPCOKE_00084 2.6e-125 S DNA binding
IOBPCOKE_00085 1.3e-18 K Helix-turn-helix XRE-family like proteins
IOBPCOKE_00086 5.1e-30 ansR 3.4.21.88 K sequence-specific DNA binding
IOBPCOKE_00087 1.5e-18 S Pfam:Peptidase_M78
IOBPCOKE_00088 3.1e-21
IOBPCOKE_00089 1.1e-81 sip L Belongs to the 'phage' integrase family
IOBPCOKE_00090 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOBPCOKE_00091 2.2e-108 vanZ V VanZ like family
IOBPCOKE_00092 1.4e-261 pgi 5.3.1.9 G Belongs to the GPI family
IOBPCOKE_00093 3.6e-142 EGP Major facilitator Superfamily
IOBPCOKE_00094 3.1e-41 EGP Major facilitator Superfamily
IOBPCOKE_00095 1.2e-196 ampC V Beta-lactamase
IOBPCOKE_00098 2.2e-249 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
IOBPCOKE_00099 7.6e-114 tdk 2.7.1.21 F thymidine kinase
IOBPCOKE_00100 5.3e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOBPCOKE_00101 3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOBPCOKE_00102 2.9e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IOBPCOKE_00103 8.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOBPCOKE_00104 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
IOBPCOKE_00105 8.6e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOBPCOKE_00106 5e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOBPCOKE_00107 4.7e-94 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOBPCOKE_00108 2.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOBPCOKE_00109 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOBPCOKE_00110 6.3e-239 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOBPCOKE_00111 7.7e-55 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IOBPCOKE_00112 3.4e-30 ywzB S Protein of unknown function (DUF1146)
IOBPCOKE_00113 6.5e-179 mbl D Cell shape determining protein MreB Mrl
IOBPCOKE_00114 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IOBPCOKE_00115 8.6e-34 S Protein of unknown function (DUF2969)
IOBPCOKE_00116 1.9e-217 rodA D Belongs to the SEDS family
IOBPCOKE_00117 3.1e-78 usp6 T universal stress protein
IOBPCOKE_00118 2.5e-35
IOBPCOKE_00119 5.5e-242 rarA L recombination factor protein RarA
IOBPCOKE_00120 1e-81 yueI S Protein of unknown function (DUF1694)
IOBPCOKE_00121 4.7e-111 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOBPCOKE_00122 9.3e-282 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IOBPCOKE_00123 8.4e-218 iscS2 2.8.1.7 E Aminotransferase class V
IOBPCOKE_00124 1.7e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IOBPCOKE_00125 2.9e-37 S Protein of unknown function (DUF3232)
IOBPCOKE_00126 7.5e-149 K Helix-turn-helix XRE-family like proteins
IOBPCOKE_00127 1.1e-29
IOBPCOKE_00128 1.8e-27 L PFAM transposase, IS4 family protein
IOBPCOKE_00129 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IOBPCOKE_00130 9.7e-69 rplI J Binds to the 23S rRNA
IOBPCOKE_00131 1.8e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IOBPCOKE_00132 3.4e-169 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
IOBPCOKE_00133 5.5e-291 S Domain of unknown function (DUF4430)
IOBPCOKE_00134 9.3e-184 U FFAT motif binding
IOBPCOKE_00135 4.8e-81 S Domain of unknown function (DUF4430)
IOBPCOKE_00136 2.7e-33 M Protein of unknown function (DUF3737)
IOBPCOKE_00137 6.2e-32 M Protein of unknown function (DUF3737)
IOBPCOKE_00138 6.8e-228 patB 4.4.1.8 E Aminotransferase, class I
IOBPCOKE_00139 1.9e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
IOBPCOKE_00140 2.4e-60 S SdpI/YhfL protein family
IOBPCOKE_00141 8.3e-131 K Transcriptional regulatory protein, C terminal
IOBPCOKE_00142 2e-272 yclK 2.7.13.3 T Histidine kinase
IOBPCOKE_00143 4.9e-150
IOBPCOKE_00144 2.9e-165
IOBPCOKE_00145 6.4e-110
IOBPCOKE_00146 1.4e-264 glnA 6.3.1.2 E glutamine synthetase
IOBPCOKE_00147 5e-62 ynbB 4.4.1.1 P aluminum resistance
IOBPCOKE_00148 6e-20 ynbB 4.4.1.1 P aluminum resistance
IOBPCOKE_00149 3.1e-17
IOBPCOKE_00150 1.1e-17
IOBPCOKE_00151 8.9e-60 CP ATPases associated with a variety of cellular activities
IOBPCOKE_00152 5.8e-22 CP ATPases associated with a variety of cellular activities
IOBPCOKE_00153 1.3e-123 V Transport permease protein
IOBPCOKE_00154 7.5e-108 V Transport permease protein
IOBPCOKE_00155 5e-306
IOBPCOKE_00156 5.2e-80
IOBPCOKE_00157 1.3e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOBPCOKE_00158 3.4e-26 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
IOBPCOKE_00159 2.4e-242 N Uncharacterized conserved protein (DUF2075)
IOBPCOKE_00160 7.8e-34 mmuP E amino acid
IOBPCOKE_00161 5.1e-179 mmuP E amino acid
IOBPCOKE_00162 9e-173 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
IOBPCOKE_00163 3.4e-230 amd 3.5.1.47 E Peptidase family M20/M25/M40
IOBPCOKE_00164 8.6e-76 S Core-2/I-Branching enzyme
IOBPCOKE_00165 6.6e-30 S Glycosyltransferase like family 2
IOBPCOKE_00166 2.7e-132
IOBPCOKE_00168 5.7e-84 S Bacterial transferase hexapeptide (six repeats)
IOBPCOKE_00169 1.5e-14 fcbD 2.7.8.12 GT2 M Glycosyltransferase like family 2
IOBPCOKE_00171 4.1e-156 P ABC-type cobalt transport system permease component CbiQ and related transporters
IOBPCOKE_00172 0.0 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
IOBPCOKE_00173 8.7e-125 S ECF-type riboflavin transporter, S component
IOBPCOKE_00174 8.8e-85 U FFAT motif binding
IOBPCOKE_00175 1.5e-44 U FFAT motif binding
IOBPCOKE_00176 6.5e-54 eutP E Ethanolamine utilisation - propanediol utilisation
IOBPCOKE_00178 1.5e-19 pfoS S Phosphotransferase system, EIIC
IOBPCOKE_00179 1.3e-111 pfoS S Phosphotransferase system, EIIC
IOBPCOKE_00181 1.8e-93
IOBPCOKE_00184 9.3e-198
IOBPCOKE_00185 3e-122 gntR1 K UTRA
IOBPCOKE_00186 1.8e-55 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
IOBPCOKE_00187 2.4e-36
IOBPCOKE_00188 3e-170 yfdH GT2 M Glycosyltransferase like family 2
IOBPCOKE_00189 2.4e-66 2.4.1.83 GT2 S GtrA-like protein
IOBPCOKE_00190 2.7e-137 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IOBPCOKE_00191 9.9e-55 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IOBPCOKE_00192 2.6e-20
IOBPCOKE_00193 6e-239 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOBPCOKE_00194 1.8e-131 znuB U ABC 3 transport family
IOBPCOKE_00195 6.1e-117 fhuC P ABC transporter
IOBPCOKE_00196 2.5e-163 psaA P Belongs to the bacterial solute-binding protein 9 family
IOBPCOKE_00197 1e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
IOBPCOKE_00198 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
IOBPCOKE_00199 1.1e-167 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IOBPCOKE_00200 6.1e-140 fruR K DeoR C terminal sensor domain
IOBPCOKE_00202 8.7e-27
IOBPCOKE_00203 7.1e-33
IOBPCOKE_00204 6.6e-34 yozG K Transcriptional regulator
IOBPCOKE_00205 2.8e-54 S Enterocin A Immunity
IOBPCOKE_00206 2.3e-127 S Archaea bacterial proteins of unknown function
IOBPCOKE_00207 8.9e-74 S Archaea bacterial proteins of unknown function
IOBPCOKE_00208 7.2e-146 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IOBPCOKE_00209 3.2e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOBPCOKE_00210 9.2e-209 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
IOBPCOKE_00211 5.1e-122 K response regulator
IOBPCOKE_00212 0.0 V ABC transporter
IOBPCOKE_00213 4.6e-297 V ABC transporter, ATP-binding protein
IOBPCOKE_00214 6.8e-139 XK27_01040 S Protein of unknown function (DUF1129)
IOBPCOKE_00215 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOBPCOKE_00216 2.1e-44 yyzM S Bacterial protein of unknown function (DUF951)
IOBPCOKE_00217 4.5e-155 spo0J K Belongs to the ParB family
IOBPCOKE_00218 3.4e-138 soj D Sporulation initiation inhibitor
IOBPCOKE_00219 4.6e-149 noc K Belongs to the ParB family
IOBPCOKE_00220 2.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IOBPCOKE_00221 1.9e-84 cvpA S Colicin V production protein
IOBPCOKE_00222 1.7e-181 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOBPCOKE_00223 5.1e-150 3.1.3.48 T Tyrosine phosphatase family
IOBPCOKE_00224 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
IOBPCOKE_00225 9.9e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
IOBPCOKE_00226 2.8e-111 K WHG domain
IOBPCOKE_00227 2.8e-20 ybbH_2 K rpiR family
IOBPCOKE_00229 5.5e-118 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IOBPCOKE_00230 1.4e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IOBPCOKE_00231 6.5e-145 cof S haloacid dehalogenase-like hydrolase
IOBPCOKE_00232 1.2e-142 pbuG S permease
IOBPCOKE_00233 2.2e-174 S cog cog1373
IOBPCOKE_00234 2e-10 K response regulator
IOBPCOKE_00235 4.5e-56 K response regulator
IOBPCOKE_00236 9.4e-41 sptS 2.7.13.3 T Histidine kinase
IOBPCOKE_00237 6.3e-56 sptS 2.7.13.3 T Histidine kinase
IOBPCOKE_00238 1e-210 EGP Major facilitator Superfamily
IOBPCOKE_00239 3.7e-72 O OsmC-like protein
IOBPCOKE_00240 3.7e-128 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
IOBPCOKE_00241 2.7e-99
IOBPCOKE_00242 3.5e-106 K LysR substrate binding domain
IOBPCOKE_00243 1.1e-19
IOBPCOKE_00244 1.6e-213 S Sterol carrier protein domain
IOBPCOKE_00245 3.4e-97 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IOBPCOKE_00246 2.8e-52 arcC 2.7.2.2 E Belongs to the carbamate kinase family
IOBPCOKE_00247 1.4e-69 arcC 2.7.2.2 E Belongs to the carbamate kinase family
IOBPCOKE_00248 2.5e-30 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IOBPCOKE_00249 2.1e-100 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IOBPCOKE_00250 1.1e-12 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IOBPCOKE_00251 5.1e-83 S Protein of unknown function (DUF3232)
IOBPCOKE_00253 1.7e-121
IOBPCOKE_00254 2.7e-17 K Helix-turn-helix XRE-family like proteins
IOBPCOKE_00255 8.2e-143 K Helix-turn-helix XRE-family like proteins
IOBPCOKE_00256 6.8e-178 L COG3547 Transposase and inactivated derivatives
IOBPCOKE_00258 6.3e-290 lsa S ABC transporter
IOBPCOKE_00259 4.8e-60 KLT Protein kinase domain
IOBPCOKE_00260 8.8e-280 KLT Protein kinase domain
IOBPCOKE_00261 1.9e-175 V ABC transporter transmembrane region
IOBPCOKE_00262 2.7e-33 S Transglycosylase associated protein
IOBPCOKE_00263 2.3e-25 lysA2 M Glycosyl hydrolases family 25
IOBPCOKE_00264 4.2e-47 M Glycosyl hydrolases family 25
IOBPCOKE_00265 2.5e-44 M Glycosyl hydrolases family 25
IOBPCOKE_00266 8.2e-28 M Glycosyl hydrolases family 25
IOBPCOKE_00267 3.1e-54
IOBPCOKE_00268 1.2e-109 XK27_00160 S Domain of unknown function (DUF5052)
IOBPCOKE_00269 4.3e-91 adk 2.7.4.3 F topology modulation protein
IOBPCOKE_00270 4.3e-52
IOBPCOKE_00271 5.4e-135
IOBPCOKE_00272 6.1e-208 EGP Major facilitator Superfamily
IOBPCOKE_00273 5.9e-103
IOBPCOKE_00274 1.5e-85 S Fic/DOC family
IOBPCOKE_00275 1.9e-19 S Fic/DOC family
IOBPCOKE_00276 2.4e-56
IOBPCOKE_00277 8.3e-91
IOBPCOKE_00278 5.1e-12 S Protein of unknown function (DUF554)
IOBPCOKE_00279 2.1e-214 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOBPCOKE_00280 0.0 pepF E oligoendopeptidase F
IOBPCOKE_00281 1.5e-09 Z012_06740 S Fic/DOC family
IOBPCOKE_00282 8.6e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IOBPCOKE_00283 2.4e-206 csaB M Glycosyl transferases group 1
IOBPCOKE_00284 5.6e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOBPCOKE_00285 2.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IOBPCOKE_00286 2.1e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IOBPCOKE_00287 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOBPCOKE_00288 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOBPCOKE_00289 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOBPCOKE_00290 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IOBPCOKE_00291 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOBPCOKE_00292 1.7e-105 rplD J Forms part of the polypeptide exit tunnel
IOBPCOKE_00293 4.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOBPCOKE_00294 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOBPCOKE_00295 4.2e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOBPCOKE_00296 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOBPCOKE_00297 1.5e-110 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOBPCOKE_00298 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOBPCOKE_00299 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
IOBPCOKE_00300 1.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOBPCOKE_00301 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOBPCOKE_00302 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOBPCOKE_00303 3.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOBPCOKE_00304 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOBPCOKE_00305 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOBPCOKE_00306 2.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOBPCOKE_00307 2.8e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOBPCOKE_00308 1.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOBPCOKE_00309 2.3e-24 rpmD J Ribosomal protein L30
IOBPCOKE_00310 1.5e-71 rplO J Binds to the 23S rRNA
IOBPCOKE_00311 4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOBPCOKE_00312 1.3e-119 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOBPCOKE_00313 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOBPCOKE_00314 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IOBPCOKE_00315 3.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOBPCOKE_00316 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOBPCOKE_00317 8.1e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOBPCOKE_00318 1.4e-60 rplQ J Ribosomal protein L17
IOBPCOKE_00319 1.1e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOBPCOKE_00320 9.5e-152 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOBPCOKE_00321 5.1e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOBPCOKE_00322 4.6e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOBPCOKE_00323 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOBPCOKE_00324 1.6e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
IOBPCOKE_00325 1.1e-71 S Protein of unknown function (DUF805)
IOBPCOKE_00326 2.5e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
IOBPCOKE_00327 2.4e-66 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IOBPCOKE_00328 2.2e-134 S membrane transporter protein
IOBPCOKE_00329 4e-127 pgm3 G Belongs to the phosphoglycerate mutase family
IOBPCOKE_00330 1.6e-163 czcD P cation diffusion facilitator family transporter
IOBPCOKE_00331 5.5e-23
IOBPCOKE_00332 2e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOBPCOKE_00333 4.9e-184 S AAA domain
IOBPCOKE_00335 5.5e-80 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IOBPCOKE_00336 9.4e-20
IOBPCOKE_00337 6.6e-33 S Domain of unknown function (DUF4393)
IOBPCOKE_00338 9.7e-83 S Domain of unknown function (DUF5067)
IOBPCOKE_00339 4.8e-63
IOBPCOKE_00341 4.3e-120 XK27_07525 3.6.1.55 F NUDIX domain
IOBPCOKE_00342 6.2e-145 2.4.2.3 F Phosphorylase superfamily
IOBPCOKE_00343 6.4e-75 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
IOBPCOKE_00345 9.4e-80 K Acetyltransferase (GNAT) domain
IOBPCOKE_00346 4.2e-53
IOBPCOKE_00347 1.9e-132 cobQ S glutamine amidotransferase
IOBPCOKE_00348 6.8e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IOBPCOKE_00349 4.6e-59 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOBPCOKE_00350 2e-110 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOBPCOKE_00351 5.4e-51 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOBPCOKE_00352 1.5e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
IOBPCOKE_00353 4.3e-98
IOBPCOKE_00354 9.3e-278 S O-antigen ligase like membrane protein
IOBPCOKE_00355 9.6e-25
IOBPCOKE_00356 1.2e-94 gmk2 2.7.4.8 F Guanylate kinase homologues.
IOBPCOKE_00357 7e-90 M NlpC/P60 family
IOBPCOKE_00358 2.1e-31 S Archaea bacterial proteins of unknown function
IOBPCOKE_00359 1.7e-38 S Antitoxin component of a toxin-antitoxin (TA) module
IOBPCOKE_00360 5.3e-50 S YoeB-like toxin of bacterial type II toxin-antitoxin system
IOBPCOKE_00361 6.3e-162 ydeE K AraC family transcriptional regulator
IOBPCOKE_00363 1.5e-177 L Lactococcus lactis RepB C-terminus
IOBPCOKE_00364 4.7e-96 ywnH 2.3.1.183 M acetyltransferase (GNAT) family
IOBPCOKE_00365 2.2e-15 K Penicillinase repressor
IOBPCOKE_00366 0.0 copB 3.6.3.4 P P-type ATPase
IOBPCOKE_00367 3.1e-72 mdt(A) EGP Major facilitator Superfamily
IOBPCOKE_00368 3.8e-18 D Alpha beta
IOBPCOKE_00369 2.7e-45
IOBPCOKE_00370 1e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IOBPCOKE_00371 7.9e-219 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IOBPCOKE_00372 4.6e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
IOBPCOKE_00373 1.7e-79 S Threonine/Serine exporter, ThrE
IOBPCOKE_00374 5.7e-138 thrE S Putative threonine/serine exporter
IOBPCOKE_00375 2.1e-288 S ABC transporter
IOBPCOKE_00376 1.6e-53
IOBPCOKE_00377 9.9e-100 rimL J Acetyltransferase (GNAT) domain
IOBPCOKE_00378 3.2e-33 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOBPCOKE_00379 1.5e-152 glnH ET ABC transporter substrate-binding protein
IOBPCOKE_00380 3e-108 gluC P ABC transporter permease
IOBPCOKE_00381 4.7e-109 glnP P ABC transporter permease
IOBPCOKE_00382 1.1e-62 S Protein of unknown function (DUF2974)
IOBPCOKE_00383 1.2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IOBPCOKE_00384 3.3e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IOBPCOKE_00385 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IOBPCOKE_00386 7.3e-189 cggR K Putative sugar-binding domain
IOBPCOKE_00387 1.3e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOBPCOKE_00388 1.3e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IOBPCOKE_00389 2e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOBPCOKE_00390 1.8e-95
IOBPCOKE_00391 7.4e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
IOBPCOKE_00392 3.3e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOBPCOKE_00393 1.6e-180 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IOBPCOKE_00394 6.4e-90 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IOBPCOKE_00395 1.4e-98 dnaQ 2.7.7.7 L DNA polymerase III
IOBPCOKE_00396 1.1e-164 murB 1.3.1.98 M Cell wall formation
IOBPCOKE_00397 3.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IOBPCOKE_00398 1.3e-129 potB P ABC transporter permease
IOBPCOKE_00399 1.1e-123 potC P ABC transporter permease
IOBPCOKE_00400 1.6e-207 potD P ABC transporter
IOBPCOKE_00401 4.2e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOBPCOKE_00402 1.2e-172 ybbR S YbbR-like protein
IOBPCOKE_00403 8.2e-257 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOBPCOKE_00404 2.1e-151 S hydrolase
IOBPCOKE_00405 9.9e-149 S Sucrose-6F-phosphate phosphohydrolase
IOBPCOKE_00406 2.1e-118
IOBPCOKE_00407 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOBPCOKE_00408 7.8e-216 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IOBPCOKE_00409 1.5e-63 licT K CAT RNA binding domain
IOBPCOKE_00410 3e-63 licT K CAT RNA binding domain
IOBPCOKE_00411 0.0 bglP G phosphotransferase system
IOBPCOKE_00413 3.1e-136 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOBPCOKE_00414 6.1e-122 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOBPCOKE_00415 2.6e-185 D Alpha beta
IOBPCOKE_00416 2.3e-54 E Amino acid permease
IOBPCOKE_00417 8.7e-151 E Amino acid permease
IOBPCOKE_00418 2.2e-31 E Amino acid permease
IOBPCOKE_00419 2.4e-66 emrY EGP Major facilitator Superfamily
IOBPCOKE_00424 1e-95 MA20_25245 K Acetyltransferase (GNAT) domain
IOBPCOKE_00427 6e-31 cspA K Cold shock protein
IOBPCOKE_00428 7.1e-89
IOBPCOKE_00429 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IOBPCOKE_00430 3.8e-184 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOBPCOKE_00431 6.3e-229 mtnE 2.6.1.83 E Aminotransferase
IOBPCOKE_00432 9.3e-152 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
IOBPCOKE_00433 7.5e-39 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOBPCOKE_00434 1.2e-125 pgm3 G Phosphoglycerate mutase family
IOBPCOKE_00435 1.7e-125 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IOBPCOKE_00436 0.0 helD 3.6.4.12 L DNA helicase
IOBPCOKE_00437 5e-200 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOBPCOKE_00440 1e-125 M NlpC/P60 family
IOBPCOKE_00441 4.8e-31 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
IOBPCOKE_00442 4.6e-154 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
IOBPCOKE_00443 7.5e-108 pncA Q Isochorismatase family
IOBPCOKE_00444 2.1e-271 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOBPCOKE_00445 1.3e-159 msmR7 K helix_turn_helix, arabinose operon control protein
IOBPCOKE_00446 2.7e-29 scrB 3.2.1.26 GH32 G invertase
IOBPCOKE_00447 5.1e-50 G phosphoenolpyruvate-dependent sugar phosphotransferase system
IOBPCOKE_00448 2.8e-39 rafA 3.2.1.22 G alpha-galactosidase
IOBPCOKE_00449 4.9e-76 rafA 3.2.1.22 G alpha-galactosidase
IOBPCOKE_00450 1.3e-34 rafA 3.2.1.22 G alpha-galactosidase
IOBPCOKE_00451 3e-37
IOBPCOKE_00452 3.2e-57 malY 4.4.1.8 E Aminotransferase, class I
IOBPCOKE_00453 1.6e-88 malY 4.4.1.8 E Aminotransferase, class I
IOBPCOKE_00454 7.6e-55
IOBPCOKE_00455 1.5e-245 brnQ U Component of the transport system for branched-chain amino acids
IOBPCOKE_00456 1.1e-81 M NlpC/P60 family
IOBPCOKE_00457 7.3e-164 EG EamA-like transporter family
IOBPCOKE_00458 5.5e-110
IOBPCOKE_00459 3.9e-79
IOBPCOKE_00460 7.6e-64 manO S Domain of unknown function (DUF956)
IOBPCOKE_00461 1.5e-174 manN G system, mannose fructose sorbose family IID component
IOBPCOKE_00462 8.1e-135 manY G PTS system
IOBPCOKE_00463 1.6e-188 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
IOBPCOKE_00464 7.6e-129 S (CBS) domain
IOBPCOKE_00465 2.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IOBPCOKE_00466 2.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOBPCOKE_00467 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOBPCOKE_00468 1.8e-34 yabO J S4 domain protein
IOBPCOKE_00469 2.6e-59 divIC D Septum formation initiator
IOBPCOKE_00470 4.1e-62 yabR J S1 RNA binding domain
IOBPCOKE_00471 1.2e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOBPCOKE_00472 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOBPCOKE_00473 3.1e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IOBPCOKE_00474 2.1e-196 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOBPCOKE_00475 1.7e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IOBPCOKE_00476 1.6e-08
IOBPCOKE_00477 2.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
IOBPCOKE_00478 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOBPCOKE_00479 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOBPCOKE_00480 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOBPCOKE_00485 2.4e-83 S COG NOG38524 non supervised orthologous group
IOBPCOKE_00486 2.8e-238 G Bacterial extracellular solute-binding protein
IOBPCOKE_00487 4.5e-247 XK27_08635 S UPF0210 protein
IOBPCOKE_00488 2.3e-41 gcvR T Belongs to the UPF0237 family
IOBPCOKE_00489 1.9e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
IOBPCOKE_00490 5.8e-08 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOBPCOKE_00491 7.2e-135 gmuR K UTRA
IOBPCOKE_00492 1.1e-61 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOBPCOKE_00493 9.8e-32 3.6.4.12 L DNA helicase
IOBPCOKE_00494 2.7e-61 S AAA domain, putative AbiEii toxin, Type IV TA system
IOBPCOKE_00496 8.4e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOBPCOKE_00497 2.9e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOBPCOKE_00498 5.5e-29 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
IOBPCOKE_00499 3.7e-45 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
IOBPCOKE_00500 9.5e-275 E Amino acid permease
IOBPCOKE_00501 1.2e-288 V ABC transporter transmembrane region
IOBPCOKE_00502 1.6e-194 2.7.7.73, 2.7.7.80 H ThiF family
IOBPCOKE_00503 1e-273 pepV 3.5.1.18 E dipeptidase PepV
IOBPCOKE_00504 2.3e-170 V Beta-lactamase
IOBPCOKE_00505 8.3e-141 ydiM G Major facilitator superfamily
IOBPCOKE_00506 3.7e-08 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IOBPCOKE_00507 2.2e-145 fabF-1 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IOBPCOKE_00508 1e-17 S Psort location Cytoplasmic, score
IOBPCOKE_00509 9.9e-40 pssE S Glycosyltransferase family 28 C-terminal domain
IOBPCOKE_00510 2.7e-101 GT4 M Glycosyl transferases group 1
IOBPCOKE_00511 1.1e-223 pbuG S permease
IOBPCOKE_00512 6.7e-35
IOBPCOKE_00513 9.3e-77 atkY K Penicillinase repressor
IOBPCOKE_00514 1.2e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IOBPCOKE_00515 1.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IOBPCOKE_00516 0.0 copA 3.6.3.54 P P-type ATPase
IOBPCOKE_00517 7.7e-37 EGP Sugar (and other) transporter
IOBPCOKE_00518 3.1e-157 EGP Sugar (and other) transporter
IOBPCOKE_00519 1.2e-18
IOBPCOKE_00520 8.5e-212
IOBPCOKE_00521 8.4e-290 clcA P chloride
IOBPCOKE_00522 2.2e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOBPCOKE_00523 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IOBPCOKE_00524 6.2e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IOBPCOKE_00525 6.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOBPCOKE_00526 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IOBPCOKE_00527 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IOBPCOKE_00528 5.2e-259 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOBPCOKE_00529 3.9e-196 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOBPCOKE_00530 1.3e-34 yaaA S S4 domain protein YaaA
IOBPCOKE_00531 1.6e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOBPCOKE_00532 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOBPCOKE_00533 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOBPCOKE_00534 4.2e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
IOBPCOKE_00535 3.1e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IOBPCOKE_00536 3.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOBPCOKE_00537 1.9e-172 mrr L restriction endonuclease
IOBPCOKE_00538 2.8e-36 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
IOBPCOKE_00539 2e-57 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
IOBPCOKE_00540 8.6e-98
IOBPCOKE_00541 3.3e-231 pbuG S permease
IOBPCOKE_00542 4.2e-110 K helix_turn_helix, mercury resistance
IOBPCOKE_00543 1.1e-08 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IOBPCOKE_00544 2.6e-52 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IOBPCOKE_00545 1.6e-140 S Uncharacterized protein conserved in bacteria (DUF2263)
IOBPCOKE_00546 5.1e-60
IOBPCOKE_00548 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IOBPCOKE_00549 1e-21
IOBPCOKE_00550 2.1e-102 S LexA-binding, inner membrane-associated putative hydrolase
IOBPCOKE_00551 3.2e-15
IOBPCOKE_00552 8.9e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IOBPCOKE_00553 2.1e-257 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
IOBPCOKE_00554 1.1e-111 V ABC transporter transmembrane region
IOBPCOKE_00555 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IOBPCOKE_00556 1e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IOBPCOKE_00557 5e-69 yslB S Protein of unknown function (DUF2507)
IOBPCOKE_00558 7.6e-205 xerS L Belongs to the 'phage' integrase family
IOBPCOKE_00559 1e-240 amtB P ammonium transporter
IOBPCOKE_00560 7.5e-180 S Oxidoreductase family, NAD-binding Rossmann fold
IOBPCOKE_00561 5.2e-118
IOBPCOKE_00562 3.9e-131
IOBPCOKE_00563 1.1e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOBPCOKE_00564 3e-110 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOBPCOKE_00565 5.3e-101 G Aldose 1-epimerase
IOBPCOKE_00566 2.7e-205 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOBPCOKE_00567 2.5e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOBPCOKE_00568 0.0 XK27_08315 M Sulfatase
IOBPCOKE_00569 4.9e-265 S Fibronectin type III domain
IOBPCOKE_00570 9.7e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOBPCOKE_00571 1.6e-53
IOBPCOKE_00573 1.6e-257 pepC 3.4.22.40 E aminopeptidase
IOBPCOKE_00574 2.7e-120 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOBPCOKE_00575 1.4e-300 oppA E ABC transporter, substratebinding protein
IOBPCOKE_00576 0.0 oppA E ABC transporter, substratebinding protein
IOBPCOKE_00577 2.8e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOBPCOKE_00578 2.9e-144 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOBPCOKE_00579 4.9e-185 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOBPCOKE_00580 1.3e-201 oppD P Belongs to the ABC transporter superfamily
IOBPCOKE_00581 3.2e-175 oppF P Belongs to the ABC transporter superfamily
IOBPCOKE_00582 7.7e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IOBPCOKE_00583 1.1e-244 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
IOBPCOKE_00585 1.6e-60 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
IOBPCOKE_00586 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IOBPCOKE_00587 2.6e-209 V ABC transporter transmembrane region
IOBPCOKE_00588 7.1e-155 S hydrolase
IOBPCOKE_00589 5.5e-41 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
IOBPCOKE_00591 1.6e-163 S SLAP domain
IOBPCOKE_00592 7.3e-87 V ABC transporter transmembrane region
IOBPCOKE_00593 1.9e-204 L COG3547 Transposase and inactivated derivatives
IOBPCOKE_00595 1e-64 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IOBPCOKE_00596 1e-28 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IOBPCOKE_00597 4.6e-160 degV S EDD domain protein, DegV family
IOBPCOKE_00598 5.7e-47
IOBPCOKE_00599 2.9e-116 G phosphoglycerate mutase
IOBPCOKE_00600 9.9e-216 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IOBPCOKE_00601 1.2e-216 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOBPCOKE_00602 8.5e-48 sugE U Multidrug resistance protein
IOBPCOKE_00603 7.3e-21 3.6.1.13 L Belongs to the Nudix hydrolase family
IOBPCOKE_00604 1.5e-83 L PFAM transposase, IS4 family protein
IOBPCOKE_00605 6.4e-42 L PFAM transposase, IS4 family protein
IOBPCOKE_00606 9.6e-138 XK27_08845 S ABC transporter, ATP-binding protein
IOBPCOKE_00607 1.7e-125 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IOBPCOKE_00608 8e-177 ABC-SBP S ABC transporter
IOBPCOKE_00609 1.5e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IOBPCOKE_00610 3e-154 S SLAP domain
IOBPCOKE_00611 1e-164 yvgN C Aldo keto reductase
IOBPCOKE_00612 0.0 tetP J elongation factor G
IOBPCOKE_00613 8.5e-90 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
IOBPCOKE_00614 4e-43 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
IOBPCOKE_00615 3.1e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOBPCOKE_00616 4.4e-168 yniA G Phosphotransferase enzyme family
IOBPCOKE_00617 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
IOBPCOKE_00618 2.3e-145 E amino acid
IOBPCOKE_00619 0.0 L Helicase C-terminal domain protein
IOBPCOKE_00620 3.5e-196 pbpX1 V Beta-lactamase
IOBPCOKE_00621 7.9e-70 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IOBPCOKE_00622 1.1e-195 V ABC transporter transmembrane region
IOBPCOKE_00624 7e-89 XK27_09675 K Acetyltransferase (GNAT) domain
IOBPCOKE_00625 3.9e-30
IOBPCOKE_00626 3e-46
IOBPCOKE_00627 1.6e-67
IOBPCOKE_00628 6.1e-72 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IOBPCOKE_00630 5.2e-89
IOBPCOKE_00631 1.6e-63 K Helix-turn-helix XRE-family like proteins
IOBPCOKE_00632 3.8e-35
IOBPCOKE_00633 3.6e-151 xerD L Phage integrase, N-terminal SAM-like domain
IOBPCOKE_00637 1.9e-29 L COG2963 Transposase and inactivated derivatives
IOBPCOKE_00638 7.7e-89 EGP Major facilitator Superfamily
IOBPCOKE_00639 5.9e-252 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOBPCOKE_00640 1.1e-98 J Acetyltransferase (GNAT) domain
IOBPCOKE_00641 1.8e-110 yjbF S SNARE associated Golgi protein
IOBPCOKE_00642 3.4e-154 I alpha/beta hydrolase fold
IOBPCOKE_00644 5.9e-126 hipB K Helix-turn-helix
IOBPCOKE_00645 1.7e-262 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IOBPCOKE_00646 7.8e-159
IOBPCOKE_00647 0.0 ydgH S MMPL family
IOBPCOKE_00648 1.5e-98 yobS K Bacterial regulatory proteins, tetR family
IOBPCOKE_00649 5.5e-159 3.5.2.6 V Beta-lactamase enzyme family
IOBPCOKE_00650 7.4e-161 corA P CorA-like Mg2+ transporter protein
IOBPCOKE_00651 4.3e-231 G Bacterial extracellular solute-binding protein
IOBPCOKE_00652 6.6e-256 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
IOBPCOKE_00653 2.7e-146 gtsC P Binding-protein-dependent transport system inner membrane component
IOBPCOKE_00654 1.9e-158 gtsB P ABC-type sugar transport systems, permease components
IOBPCOKE_00655 2.4e-203 malK P ATPases associated with a variety of cellular activities
IOBPCOKE_00656 1.6e-282 pipD E Dipeptidase
IOBPCOKE_00657 5e-159 endA F DNA RNA non-specific endonuclease
IOBPCOKE_00658 5.7e-164 dnaQ 2.7.7.7 L EXOIII
IOBPCOKE_00659 3.7e-159 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IOBPCOKE_00660 8.7e-69 L TIGRFAM transposase, IS605 OrfB family
IOBPCOKE_00666 9.3e-40 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IOBPCOKE_00668 7.7e-47 V ABC transporter transmembrane region
IOBPCOKE_00669 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
IOBPCOKE_00670 2.5e-247 ynbB 4.4.1.1 P aluminum resistance
IOBPCOKE_00671 1.7e-117 ktrA P domain protein
IOBPCOKE_00672 1.4e-179 ktrB P Potassium uptake protein
IOBPCOKE_00673 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
IOBPCOKE_00674 1.3e-81 C Flavodoxin
IOBPCOKE_00675 4.4e-112 3.6.1.27 I Acid phosphatase homologues
IOBPCOKE_00676 5.1e-105 lacA 2.3.1.79 S Transferase hexapeptide repeat
IOBPCOKE_00677 2.6e-208 pbpX1 V Beta-lactamase
IOBPCOKE_00678 3.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
IOBPCOKE_00679 3.1e-93 S ECF-type riboflavin transporter, S component
IOBPCOKE_00680 8.1e-232 S Putative peptidoglycan binding domain
IOBPCOKE_00681 1.7e-235 mepA V MATE efflux family protein
IOBPCOKE_00682 2.3e-256 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IOBPCOKE_00683 6.5e-34
IOBPCOKE_00684 1.4e-29 fic D Fic/DOC family
IOBPCOKE_00685 9.7e-61
IOBPCOKE_00686 9e-295 P ABC transporter
IOBPCOKE_00687 1.5e-294 V ABC-type multidrug transport system, ATPase and permease components
IOBPCOKE_00688 9.2e-69 S Putative adhesin
IOBPCOKE_00689 1.3e-58 ypaA S Protein of unknown function (DUF1304)
IOBPCOKE_00690 2.4e-37 yvdE K helix_turn _helix lactose operon repressor
IOBPCOKE_00691 6.3e-90 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IOBPCOKE_00692 4.4e-28
IOBPCOKE_00693 3.6e-93 L COG2963 Transposase and inactivated derivatives
IOBPCOKE_00694 8e-63 S Protein of unknown function (DUF2974)
IOBPCOKE_00695 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
IOBPCOKE_00696 5.1e-38 ynzC S UPF0291 protein
IOBPCOKE_00697 2.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOBPCOKE_00698 2.5e-149 E GDSL-like Lipase/Acylhydrolase family
IOBPCOKE_00699 6.4e-122 ung2 3.2.2.27 L Uracil-DNA glycosylase
IOBPCOKE_00700 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOBPCOKE_00701 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IOBPCOKE_00702 1.5e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOBPCOKE_00703 4.5e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IOBPCOKE_00704 6.4e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOBPCOKE_00705 3.2e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IOBPCOKE_00706 2.8e-196 L Transposase and inactivated derivatives, IS30 family
IOBPCOKE_00707 4.1e-259 yfnA E amino acid
IOBPCOKE_00708 7e-34
IOBPCOKE_00709 5.5e-288 pipD E Dipeptidase
IOBPCOKE_00710 1.3e-166 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOBPCOKE_00711 0.0 smc D Required for chromosome condensation and partitioning
IOBPCOKE_00712 1.3e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOBPCOKE_00713 2.4e-128 oppA E ABC transporter substrate-binding protein
IOBPCOKE_00714 1.7e-72 oppA E ABC transporter substrate-binding protein
IOBPCOKE_00715 2.9e-23 oppA E ABC transporter substrate-binding protein
IOBPCOKE_00716 0.0 oppA E ABC transporter substrate-binding protein
IOBPCOKE_00717 3.3e-148 oppC P Binding-protein-dependent transport system inner membrane component
IOBPCOKE_00718 1.7e-176 oppB P ABC transporter permease
IOBPCOKE_00719 2.8e-182 oppF P Belongs to the ABC transporter superfamily
IOBPCOKE_00720 7.3e-197 oppD P Belongs to the ABC transporter superfamily
IOBPCOKE_00721 3.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOBPCOKE_00722 5.8e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IOBPCOKE_00723 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IOBPCOKE_00724 1.1e-306 yloV S DAK2 domain fusion protein YloV
IOBPCOKE_00725 6.8e-57 asp S Asp23 family, cell envelope-related function
IOBPCOKE_00726 1.1e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IOBPCOKE_00727 1.6e-51
IOBPCOKE_00728 1.4e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
IOBPCOKE_00729 5e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IOBPCOKE_00730 1.1e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IOBPCOKE_00731 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IOBPCOKE_00732 2.4e-147 stp 3.1.3.16 T phosphatase
IOBPCOKE_00733 2e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IOBPCOKE_00734 1.3e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOBPCOKE_00735 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOBPCOKE_00736 6.5e-34 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOBPCOKE_00737 7.3e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
IOBPCOKE_00738 2.4e-80 6.3.3.2 S ASCH
IOBPCOKE_00739 3.3e-308 recN L May be involved in recombinational repair of damaged DNA
IOBPCOKE_00740 4.3e-152 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IOBPCOKE_00741 1.6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IOBPCOKE_00742 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOBPCOKE_00743 6.6e-176 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOBPCOKE_00744 3e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOBPCOKE_00745 6.2e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOBPCOKE_00746 2.4e-69 yqhY S Asp23 family, cell envelope-related function
IOBPCOKE_00747 3.7e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOBPCOKE_00748 8.9e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IOBPCOKE_00749 2.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IOBPCOKE_00750 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IOBPCOKE_00751 1.7e-257 S Uncharacterized protein conserved in bacteria (DUF2325)
IOBPCOKE_00752 2.4e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IOBPCOKE_00753 9.8e-58 pacL 3.6.3.8 P P-type ATPase
IOBPCOKE_00754 4.5e-77 pacL 3.6.3.8 P P-type ATPase
IOBPCOKE_00755 2.2e-117 pacL 3.6.3.8 P P-type ATPase
IOBPCOKE_00756 1.7e-168 pacL 3.6.3.8 P P-type ATPase
IOBPCOKE_00757 8.6e-226 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOBPCOKE_00758 1.5e-261 epsU S Polysaccharide biosynthesis protein
IOBPCOKE_00759 9.7e-137 M Glycosyltransferase sugar-binding region containing DXD motif
IOBPCOKE_00760 4.8e-87 ydcK S Belongs to the SprT family
IOBPCOKE_00762 1.6e-104 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
IOBPCOKE_00763 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IOBPCOKE_00764 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOBPCOKE_00765 4.4e-211 camS S sex pheromone
IOBPCOKE_00766 5.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOBPCOKE_00767 7.6e-261 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOBPCOKE_00768 2.9e-276 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOBPCOKE_00769 1e-170 yegS 2.7.1.107 G Lipid kinase
IOBPCOKE_00770 4.7e-115 S Protein of unknown function (DUF1211)
IOBPCOKE_00771 4.9e-120 ybhL S Belongs to the BI1 family
IOBPCOKE_00772 1.4e-27
IOBPCOKE_00773 2.3e-246 nhaC C Na H antiporter NhaC
IOBPCOKE_00774 3.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOBPCOKE_00775 2.2e-39 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOBPCOKE_00776 9.6e-68 S Protein of unknown function (DUF3290)
IOBPCOKE_00778 7.3e-33 S ABC-2 family transporter protein
IOBPCOKE_00779 2.8e-29 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
IOBPCOKE_00780 4.8e-82 racA K Domain of unknown function (DUF1836)
IOBPCOKE_00781 1.2e-154 yitS S EDD domain protein, DegV family
IOBPCOKE_00785 3.1e-150 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IOBPCOKE_00786 9.1e-51
IOBPCOKE_00787 4.5e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IOBPCOKE_00788 8.3e-31 mgtC S MgtC family
IOBPCOKE_00789 4.5e-77 mgtC S MgtC family
IOBPCOKE_00790 1.4e-21 bglH 3.2.1.86 GT1 G beta-glucosidase activity
IOBPCOKE_00791 2e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOBPCOKE_00792 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IOBPCOKE_00793 9.4e-56 yheA S Belongs to the UPF0342 family
IOBPCOKE_00794 2.4e-231 yhaO L Ser Thr phosphatase family protein
IOBPCOKE_00795 0.0 L AAA domain
IOBPCOKE_00796 3.4e-188 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOBPCOKE_00797 6.2e-78 S PAS domain
IOBPCOKE_00798 2.4e-156 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOBPCOKE_00799 8e-28
IOBPCOKE_00800 3.1e-80 hit FG Scavenger mRNA decapping enzyme C-term binding
IOBPCOKE_00801 1.2e-32 S Plasmid maintenance system killer
IOBPCOKE_00802 3.8e-54 higA K Helix-turn-helix XRE-family like proteins
IOBPCOKE_00803 3.9e-136 ecsA V ABC transporter, ATP-binding protein
IOBPCOKE_00804 2e-214 ecsB U ABC transporter
IOBPCOKE_00805 1e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOBPCOKE_00806 7.3e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IOBPCOKE_00807 3.3e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOBPCOKE_00808 1e-259
IOBPCOKE_00809 2.8e-08 cylB V ABC-2 type transporter
IOBPCOKE_00813 2.6e-10 V ABC transporter (Permease)
IOBPCOKE_00814 4.8e-44
IOBPCOKE_00815 2.9e-230 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IOBPCOKE_00816 2.5e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IOBPCOKE_00817 7.1e-214 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOBPCOKE_00818 1.9e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOBPCOKE_00819 7.5e-39 yajC U Preprotein translocase
IOBPCOKE_00820 7.9e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOBPCOKE_00821 3.5e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOBPCOKE_00822 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IOBPCOKE_00823 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IOBPCOKE_00824 2.9e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOBPCOKE_00825 3.9e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOBPCOKE_00826 3.9e-90
IOBPCOKE_00827 1.3e-45
IOBPCOKE_00828 6.1e-91 2.7.1.199, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IOBPCOKE_00829 1.8e-31 scrR K Transcriptional regulator, LacI family
IOBPCOKE_00830 1.9e-118 scrR K Transcriptional regulator, LacI family
IOBPCOKE_00831 8.5e-123 liaI S membrane
IOBPCOKE_00832 6.7e-78 XK27_02470 K LytTr DNA-binding domain
IOBPCOKE_00833 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IOBPCOKE_00834 0.0 uup S ABC transporter, ATP-binding protein
IOBPCOKE_00837 0.0 G Belongs to the glycosyl hydrolase 31 family
IOBPCOKE_00838 5.7e-80 ntd 2.4.2.6 F Nucleoside
IOBPCOKE_00839 1.7e-63 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOBPCOKE_00840 2.6e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
IOBPCOKE_00841 8.5e-87 uspA T universal stress protein
IOBPCOKE_00842 4.5e-153 phnD P Phosphonate ABC transporter
IOBPCOKE_00843 5.2e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IOBPCOKE_00844 6.5e-129 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
IOBPCOKE_00845 1.2e-149 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
IOBPCOKE_00846 2e-108 tag 3.2.2.20 L glycosylase
IOBPCOKE_00847 8.7e-84
IOBPCOKE_00848 3.4e-274 S Calcineurin-like phosphoesterase
IOBPCOKE_00849 0.0 asnB 6.3.5.4 E Asparagine synthase
IOBPCOKE_00850 2.8e-254 yxbA 6.3.1.12 S ATP-grasp enzyme
IOBPCOKE_00853 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IOBPCOKE_00854 4.3e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOBPCOKE_00855 4.1e-101 S Iron-sulfur cluster assembly protein
IOBPCOKE_00856 6.1e-232 XK27_04775 S PAS domain
IOBPCOKE_00859 2.1e-117 K UTRA domain
IOBPCOKE_00860 3.4e-32 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOBPCOKE_00861 9.7e-121 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOBPCOKE_00862 1.1e-82 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOBPCOKE_00863 6.8e-89 S Aldo keto reductase
IOBPCOKE_00864 1.2e-68 S Aldo keto reductase
IOBPCOKE_00865 8e-179 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
IOBPCOKE_00866 1.1e-81
IOBPCOKE_00867 2.3e-17 C FMN_bind
IOBPCOKE_00868 9.9e-302 I Protein of unknown function (DUF2974)
IOBPCOKE_00869 6.4e-107 3.6.1.55 F NUDIX domain
IOBPCOKE_00870 1.8e-206 pbpX1 V Beta-lactamase
IOBPCOKE_00871 1.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOBPCOKE_00872 7.1e-217 aspC 2.6.1.1 E Aminotransferase
IOBPCOKE_00873 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOBPCOKE_00874 4.9e-176 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOBPCOKE_00875 9.5e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IOBPCOKE_00876 3.6e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IOBPCOKE_00877 1.7e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOBPCOKE_00878 5.4e-264 lysC 2.7.2.4 E Belongs to the aspartokinase family
IOBPCOKE_00879 1.2e-191 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IOBPCOKE_00880 1.1e-178 yjeM E Amino Acid
IOBPCOKE_00881 1.2e-83 yjeM E Amino Acid
IOBPCOKE_00882 3.1e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOBPCOKE_00883 8e-105 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IOBPCOKE_00884 1.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IOBPCOKE_00885 7.6e-86 S ECF transporter, substrate-specific component
IOBPCOKE_00886 9.6e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
IOBPCOKE_00887 7.9e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOBPCOKE_00888 2.4e-59 yabA L Involved in initiation control of chromosome replication
IOBPCOKE_00889 1.5e-155 holB 2.7.7.7 L DNA polymerase III
IOBPCOKE_00890 2.2e-51 yaaQ S Cyclic-di-AMP receptor
IOBPCOKE_00891 8.7e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOBPCOKE_00892 4.9e-35 S Protein of unknown function (DUF2508)
IOBPCOKE_00893 2.1e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOBPCOKE_00894 5e-38 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IOBPCOKE_00895 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOBPCOKE_00896 6.9e-92 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOBPCOKE_00897 7.7e-117 rsmC 2.1.1.172 J Methyltransferase
IOBPCOKE_00898 1.1e-80 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
IOBPCOKE_00899 2.4e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOBPCOKE_00900 5.4e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOBPCOKE_00901 5.5e-159 yfdV S Membrane transport protein
IOBPCOKE_00902 4.3e-27 yfdV S Membrane transport protein
IOBPCOKE_00903 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
IOBPCOKE_00904 7.8e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOBPCOKE_00905 1.1e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOBPCOKE_00906 7e-156 pstA P Phosphate transport system permease protein PstA
IOBPCOKE_00907 3.7e-174 pstC P probably responsible for the translocation of the substrate across the membrane
IOBPCOKE_00908 6.2e-157 pstS P Phosphate
IOBPCOKE_00909 8.8e-110 S ABC-2 family transporter protein
IOBPCOKE_00910 3.5e-52 S ABC transporter
IOBPCOKE_00911 3.9e-33
IOBPCOKE_00912 2.1e-39
IOBPCOKE_00913 1.2e-91 3.6.1.55 L NUDIX domain
IOBPCOKE_00914 3.5e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IOBPCOKE_00915 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IOBPCOKE_00917 2.5e-112 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IOBPCOKE_00918 4.8e-34 padC Q Phenolic acid decarboxylase
IOBPCOKE_00919 1.2e-94 padR K Virulence activator alpha C-term
IOBPCOKE_00920 1.5e-110 M ErfK YbiS YcfS YnhG
IOBPCOKE_00921 5.6e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOBPCOKE_00922 5.8e-244 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IOBPCOKE_00924 2e-49 pspC KT PspC domain
IOBPCOKE_00925 2.5e-49 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
IOBPCOKE_00926 3.5e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IOBPCOKE_00927 1.7e-29 frnE Q DSBA-like thioredoxin domain
IOBPCOKE_00928 3.5e-18 frnE Q DSBA-like thioredoxin domain
IOBPCOKE_00929 1.7e-10 frnE Q DSBA-like thioredoxin domain
IOBPCOKE_00930 3.1e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOBPCOKE_00931 7.2e-118 M1-798 K Rhodanese Homology Domain
IOBPCOKE_00932 5.2e-60 CO Thioredoxin
IOBPCOKE_00933 5.6e-21
IOBPCOKE_00935 1.5e-10 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
IOBPCOKE_00936 1.3e-40 UW LPXTG-motif cell wall anchor domain protein
IOBPCOKE_00937 5.6e-18 infB UW LPXTG-motif cell wall anchor domain protein
IOBPCOKE_00938 2.5e-35 infB UW LPXTG-motif cell wall anchor domain protein
IOBPCOKE_00939 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IOBPCOKE_00940 1.2e-147 yihY S Belongs to the UPF0761 family
IOBPCOKE_00941 5.5e-163 map 3.4.11.18 E Methionine Aminopeptidase
IOBPCOKE_00942 1.7e-78 fld C Flavodoxin
IOBPCOKE_00943 5.3e-90 gtcA S Teichoic acid glycosylation protein
IOBPCOKE_00944 5.9e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOBPCOKE_00945 2.7e-25
IOBPCOKE_00947 1.1e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOBPCOKE_00948 3.7e-208 yfmL 3.6.4.13 L DEAD DEAH box helicase
IOBPCOKE_00949 2.3e-130 M Glycosyl hydrolases family 25
IOBPCOKE_00950 5.3e-23 potE E amino acid
IOBPCOKE_00951 1.9e-142 potE E amino acid
IOBPCOKE_00952 1.5e-106 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IOBPCOKE_00953 3.1e-240 yhdP S Transporter associated domain
IOBPCOKE_00954 6.6e-28 C nitroreductase
IOBPCOKE_00955 2.5e-18 C nitroreductase
IOBPCOKE_00956 6.7e-41
IOBPCOKE_00957 3.8e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IOBPCOKE_00958 3.1e-45
IOBPCOKE_00960 1.3e-23 glvR K Helix-turn-helix domain, rpiR family
IOBPCOKE_00961 1.5e-78 glvR K Helix-turn-helix domain, rpiR family
IOBPCOKE_00962 1.9e-119 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
IOBPCOKE_00963 2e-54 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
IOBPCOKE_00964 5.6e-130 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
IOBPCOKE_00965 8.2e-37 S hydrolase
IOBPCOKE_00966 5e-17 S hydrolase
IOBPCOKE_00967 1.1e-161 rssA S Phospholipase, patatin family
IOBPCOKE_00968 9.9e-29
IOBPCOKE_00970 2.2e-131 K response regulator
IOBPCOKE_00971 8.2e-308 vicK 2.7.13.3 T Histidine kinase
IOBPCOKE_00972 1.3e-243 yycH S YycH protein
IOBPCOKE_00973 6.9e-150 yycI S YycH protein
IOBPCOKE_00974 3.3e-149 vicX 3.1.26.11 S domain protein
IOBPCOKE_00975 6.9e-218 htrA 3.4.21.107 O serine protease
IOBPCOKE_00976 2.1e-90 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOBPCOKE_00977 6e-176 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
IOBPCOKE_00978 1.4e-92 P Cobalt transport protein
IOBPCOKE_00979 1.3e-249 cbiO1 S ABC transporter, ATP-binding protein
IOBPCOKE_00980 8.7e-173 K helix_turn_helix, arabinose operon control protein
IOBPCOKE_00981 2.9e-60 L hmm pf00665
IOBPCOKE_00982 5.6e-08 L hmm pf00665
IOBPCOKE_00983 1.2e-18 L hmm pf00665
IOBPCOKE_00984 3.7e-66 L Helix-turn-helix domain
IOBPCOKE_00985 1e-162 htpX O Belongs to the peptidase M48B family
IOBPCOKE_00986 2.3e-96 lemA S LemA family
IOBPCOKE_00987 4.3e-195 ybiR P Citrate transporter
IOBPCOKE_00988 5.9e-70 S Iron-sulphur cluster biosynthesis
IOBPCOKE_00989 1.9e-16 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
IOBPCOKE_00990 1.2e-17
IOBPCOKE_00991 7.8e-118
IOBPCOKE_00992 3.5e-85
IOBPCOKE_00993 2.6e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOBPCOKE_00994 1e-178 S Alpha/beta hydrolase of unknown function (DUF915)
IOBPCOKE_00995 5.6e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOBPCOKE_00996 8.8e-141 ypuA S Protein of unknown function (DUF1002)
IOBPCOKE_00997 1.2e-159 epsV 2.7.8.12 S glycosyl transferase family 2
IOBPCOKE_00998 2.5e-126 S Alpha/beta hydrolase family
IOBPCOKE_00999 1e-116 GM NmrA-like family
IOBPCOKE_01000 9.5e-66
IOBPCOKE_01001 1.3e-182 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOBPCOKE_01002 6.4e-125 luxT K Bacterial regulatory proteins, tetR family
IOBPCOKE_01003 1e-129
IOBPCOKE_01004 1.7e-263 glnPH2 P ABC transporter permease
IOBPCOKE_01005 8.1e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOBPCOKE_01006 2.2e-232 S Cysteine-rich secretory protein family
IOBPCOKE_01007 2.4e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IOBPCOKE_01008 1.5e-95
IOBPCOKE_01009 1.7e-202 yibE S overlaps another CDS with the same product name
IOBPCOKE_01010 7.6e-130 yibF S overlaps another CDS with the same product name
IOBPCOKE_01011 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOBPCOKE_01012 1.7e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IOBPCOKE_01013 1.4e-127 S Haloacid dehalogenase-like hydrolase
IOBPCOKE_01014 2.1e-114 radC L DNA repair protein
IOBPCOKE_01015 6.4e-174 mreB D cell shape determining protein MreB
IOBPCOKE_01016 1e-148 mreC M Involved in formation and maintenance of cell shape
IOBPCOKE_01017 1.1e-95 mreD
IOBPCOKE_01018 6.5e-13 S Protein of unknown function (DUF4044)
IOBPCOKE_01019 2.2e-54 S Protein of unknown function (DUF3397)
IOBPCOKE_01020 1.8e-77 mraZ K Belongs to the MraZ family
IOBPCOKE_01021 2e-183 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOBPCOKE_01022 1.4e-54 ftsL D Cell division protein FtsL
IOBPCOKE_01023 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IOBPCOKE_01024 1.3e-34 ftsI 3.4.16.4 M Penicillin-binding Protein
IOBPCOKE_01025 7.1e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOBPCOKE_01026 4.3e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOBPCOKE_01027 8e-210 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOBPCOKE_01028 1.1e-150 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IOBPCOKE_01029 1.3e-233 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IOBPCOKE_01030 4.7e-209 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOBPCOKE_01031 1.3e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOBPCOKE_01032 9e-47 yggT S YGGT family
IOBPCOKE_01033 3.3e-149 ylmH S S4 domain protein
IOBPCOKE_01034 1.3e-100 gpsB D DivIVA domain protein
IOBPCOKE_01035 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOBPCOKE_01036 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
IOBPCOKE_01037 3.4e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IOBPCOKE_01038 3.2e-39
IOBPCOKE_01039 2.9e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOBPCOKE_01040 5.4e-217 iscS 2.8.1.7 E Aminotransferase class V
IOBPCOKE_01041 1.4e-56 XK27_04120 S Putative amino acid metabolism
IOBPCOKE_01042 2.7e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IOBPCOKE_01043 7.3e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IOBPCOKE_01044 7.7e-104 S Repeat protein
IOBPCOKE_01045 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IOBPCOKE_01046 3.8e-105 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IOBPCOKE_01047 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOBPCOKE_01048 4.2e-33 ykzG S Belongs to the UPF0356 family
IOBPCOKE_01049 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOBPCOKE_01050 0.0 typA T GTP-binding protein TypA
IOBPCOKE_01051 4.7e-208 ftsW D Belongs to the SEDS family
IOBPCOKE_01052 3e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IOBPCOKE_01053 2.2e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IOBPCOKE_01054 2.7e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOBPCOKE_01055 6.4e-193 ylbL T Belongs to the peptidase S16 family
IOBPCOKE_01056 2.5e-84 comEA L Competence protein ComEA
IOBPCOKE_01057 0.0 comEC S Competence protein ComEC
IOBPCOKE_01058 4.8e-174 holA 2.7.7.7 L DNA polymerase III delta subunit
IOBPCOKE_01059 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
IOBPCOKE_01060 1.1e-255 pepC 3.4.22.40 E aminopeptidase
IOBPCOKE_01061 5.8e-58 hsp O Belongs to the small heat shock protein (HSP20) family
IOBPCOKE_01062 4.7e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOBPCOKE_01063 4.9e-114
IOBPCOKE_01065 3.1e-115 E Belongs to the SOS response-associated peptidase family
IOBPCOKE_01066 2.8e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOBPCOKE_01067 1.5e-91 comEB 3.5.4.12 F MafB19-like deaminase
IOBPCOKE_01068 4.6e-109 S TPM domain
IOBPCOKE_01069 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
IOBPCOKE_01070 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOBPCOKE_01071 4.6e-148 tatD L hydrolase, TatD family
IOBPCOKE_01072 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IOBPCOKE_01073 1.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOBPCOKE_01074 1e-38 veg S Biofilm formation stimulator VEG
IOBPCOKE_01075 5.3e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IOBPCOKE_01076 4.2e-208 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOBPCOKE_01077 7.7e-106 S SLAP domain
IOBPCOKE_01078 4.7e-80 S SLAP domain
IOBPCOKE_01079 4.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOBPCOKE_01080 1.1e-55 2.7.1.2 GK ROK family
IOBPCOKE_01081 9.5e-69 GK ROK family
IOBPCOKE_01082 5.5e-43
IOBPCOKE_01083 1.6e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOBPCOKE_01084 5.5e-68 S Domain of unknown function (DUF1934)
IOBPCOKE_01085 9.7e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IOBPCOKE_01086 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOBPCOKE_01087 5.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOBPCOKE_01088 1.4e-29 S Haloacid dehalogenase-like hydrolase
IOBPCOKE_01089 3.5e-42 S Haloacid dehalogenase-like hydrolase
IOBPCOKE_01090 5.7e-285 pipD E Dipeptidase
IOBPCOKE_01091 3.7e-159 msmR K AraC-like ligand binding domain
IOBPCOKE_01092 2.2e-219 pbuX F xanthine permease
IOBPCOKE_01093 1.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOBPCOKE_01094 3e-53 K DNA-binding helix-turn-helix protein
IOBPCOKE_01095 4e-19 K Helix-turn-helix
IOBPCOKE_01096 4.9e-17 K Helix-turn-helix
IOBPCOKE_01097 1e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IOBPCOKE_01099 1.6e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
IOBPCOKE_01100 5.2e-41 S RelB antitoxin
IOBPCOKE_01101 8.4e-15 repA S Replication initiator protein A
IOBPCOKE_01102 2.4e-48 E Zn peptidase
IOBPCOKE_01103 1.4e-38 ps115 K Helix-turn-helix XRE-family like proteins
IOBPCOKE_01104 6.3e-43
IOBPCOKE_01105 2.8e-169 S Bacteriocin helveticin-J
IOBPCOKE_01106 5.7e-119
IOBPCOKE_01108 1.2e-16
IOBPCOKE_01109 4.7e-40 ropB K Transcriptional regulator
IOBPCOKE_01110 8.8e-22 ropB K Transcriptional regulator
IOBPCOKE_01112 2.4e-100
IOBPCOKE_01113 4.3e-20 K Helix-turn-helix XRE-family like proteins
IOBPCOKE_01115 3.9e-59 speG J Acetyltransferase (GNAT) domain
IOBPCOKE_01117 2.2e-67 L Transposase DDE domain
IOBPCOKE_01122 3.8e-37 repA S Replication initiator protein A
IOBPCOKE_01123 6.3e-91 bioY S BioY family
IOBPCOKE_01124 1.4e-189 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IOBPCOKE_01125 9.9e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IOBPCOKE_01126 3.1e-144 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IOBPCOKE_01127 3.5e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IOBPCOKE_01128 2.5e-261 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IOBPCOKE_01129 2.7e-73 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IOBPCOKE_01130 3.7e-79 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IOBPCOKE_01131 2.7e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IOBPCOKE_01132 8.6e-128 IQ reductase
IOBPCOKE_01133 2e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IOBPCOKE_01134 1.4e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOBPCOKE_01135 4.5e-180 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOBPCOKE_01136 9.6e-80 marR K Transcriptional regulator
IOBPCOKE_01137 3.8e-78 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IOBPCOKE_01138 1e-188 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
IOBPCOKE_01139 1.8e-13 ytgB S Transglycosylase associated protein
IOBPCOKE_01140 7.2e-101 L Resolvase, N terminal domain
IOBPCOKE_01141 6.1e-130 L Transposase
IOBPCOKE_01142 6e-73 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IOBPCOKE_01143 9.7e-158 glcU U sugar transport
IOBPCOKE_01144 7.3e-55 udk 2.7.1.48 F Zeta toxin
IOBPCOKE_01145 8e-48 udk 2.7.1.48 F Zeta toxin
IOBPCOKE_01146 2.2e-157 EGP Major facilitator superfamily
IOBPCOKE_01147 1.1e-101 S ABC-type cobalt transport system, permease component
IOBPCOKE_01148 0.0 V ABC transporter transmembrane region
IOBPCOKE_01149 1e-291 XK27_09600 V ABC transporter, ATP-binding protein
IOBPCOKE_01150 5.1e-81 K Transcriptional regulator, MarR family
IOBPCOKE_01151 6.4e-148 glnH ET ABC transporter
IOBPCOKE_01152 4.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
IOBPCOKE_01153 4e-147
IOBPCOKE_01154 2.2e-311 ybiT S ABC transporter, ATP-binding protein
IOBPCOKE_01155 7.8e-210 pepA E M42 glutamyl aminopeptidase
IOBPCOKE_01156 5.1e-218 mdtG EGP Major facilitator Superfamily
IOBPCOKE_01157 8.3e-263 emrY EGP Major facilitator Superfamily
IOBPCOKE_01158 1.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOBPCOKE_01159 2.1e-241 pyrP F Permease
IOBPCOKE_01160 1.9e-10 EGP Major facilitator Superfamily
IOBPCOKE_01161 1.2e-194 O Heat shock 70 kDa protein
IOBPCOKE_01162 4.7e-42
IOBPCOKE_01163 2.8e-51 repA S Replication initiator protein A
IOBPCOKE_01164 1.5e-40
IOBPCOKE_01165 4.8e-23
IOBPCOKE_01166 1.1e-86 traA L MobA MobL family protein
IOBPCOKE_01167 3.2e-77
IOBPCOKE_01168 1.7e-18
IOBPCOKE_01169 3.3e-190 L Psort location Cytoplasmic, score
IOBPCOKE_01170 1.2e-88 tnp2PF3 L Transposase
IOBPCOKE_01171 2.4e-37 L Transposase
IOBPCOKE_01173 1.4e-16
IOBPCOKE_01176 1.7e-162 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IOBPCOKE_01177 8e-205 ydiM G Major Facilitator Superfamily
IOBPCOKE_01178 6.4e-96 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IOBPCOKE_01179 9e-19 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IOBPCOKE_01180 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IOBPCOKE_01181 1.3e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOBPCOKE_01182 1.5e-219 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOBPCOKE_01183 3.9e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IOBPCOKE_01184 1.3e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOBPCOKE_01185 8.8e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOBPCOKE_01186 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOBPCOKE_01187 2.4e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOBPCOKE_01188 4.9e-201 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IOBPCOKE_01189 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IOBPCOKE_01190 4.3e-244 purD 6.3.4.13 F Belongs to the GARS family
IOBPCOKE_01191 1.1e-214 S Domain of unknown function (DUF3883)
IOBPCOKE_01192 1.4e-223 S SLAP domain
IOBPCOKE_01196 4.1e-133 G Peptidase_C39 like family
IOBPCOKE_01197 1.4e-66 M NlpC/P60 family
IOBPCOKE_01198 7.9e-51 M NlpC/P60 family
IOBPCOKE_01199 2.6e-38
IOBPCOKE_01200 2.7e-67
IOBPCOKE_01201 1.1e-55 S Iron-sulfur cluster assembly protein
IOBPCOKE_01202 9.1e-148 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IOBPCOKE_01203 3.1e-124 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IOBPCOKE_01204 5.2e-23
IOBPCOKE_01205 7.2e-49
IOBPCOKE_01206 1.2e-209 G Major Facilitator Superfamily
IOBPCOKE_01207 0.0 3.6.3.8 P P-type ATPase
IOBPCOKE_01208 1.1e-113 yufQ S Belongs to the binding-protein-dependent transport system permease family
IOBPCOKE_01209 2.5e-27 yufQ S Belongs to the binding-protein-dependent transport system permease family
IOBPCOKE_01210 4e-57 yufP S Belongs to the binding-protein-dependent transport system permease family
IOBPCOKE_01211 0.0 V FtsX-like permease family
IOBPCOKE_01212 1.7e-134 cysA V ABC transporter, ATP-binding protein
IOBPCOKE_01213 7e-242 S response to antibiotic
IOBPCOKE_01214 4.4e-126
IOBPCOKE_01215 3.2e-15
IOBPCOKE_01216 7.1e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
IOBPCOKE_01217 7.4e-37 glvR K Helix-turn-helix domain, rpiR family
IOBPCOKE_01218 4.5e-40
IOBPCOKE_01219 1.7e-66
IOBPCOKE_01220 3.3e-94
IOBPCOKE_01221 1.4e-83 3.2.2.20 K acetyltransferase
IOBPCOKE_01222 2.6e-98 pbpX2 V Beta-lactamase
IOBPCOKE_01223 4e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IOBPCOKE_01224 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
IOBPCOKE_01225 6.5e-276 E Amino acid permease
IOBPCOKE_01226 4.4e-07
IOBPCOKE_01227 1.3e-26
IOBPCOKE_01228 6.9e-22 ybbH_2 K rpiR family
IOBPCOKE_01229 1.4e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOBPCOKE_01230 5.2e-161 yeaE S Aldo/keto reductase family
IOBPCOKE_01231 2.2e-97 S ECF transporter, substrate-specific component
IOBPCOKE_01232 4e-17 macB_3 V ABC transporter, ATP-binding protein
IOBPCOKE_01233 8.1e-158 macB_3 V ABC transporter, ATP-binding protein
IOBPCOKE_01234 2.5e-122 macB_3 V ABC transporter, ATP-binding protein
IOBPCOKE_01235 7.2e-46 macB_3 V ABC transporter, ATP-binding protein
IOBPCOKE_01236 1.2e-12 macB_3 V ABC transporter, ATP-binding protein
IOBPCOKE_01237 3.3e-195 S DUF218 domain
IOBPCOKE_01238 4.6e-120 S CAAX protease self-immunity
IOBPCOKE_01239 2.4e-46
IOBPCOKE_01240 2.9e-159 mutR K Helix-turn-helix XRE-family like proteins
IOBPCOKE_01241 8.9e-81 S Putative adhesin
IOBPCOKE_01242 1e-282 V ABC transporter transmembrane region
IOBPCOKE_01243 1.6e-47 S YoeB-like toxin of bacterial type II toxin-antitoxin system
IOBPCOKE_01244 1.7e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IOBPCOKE_01245 6.9e-204 napA P Sodium/hydrogen exchanger family
IOBPCOKE_01246 0.0 cadA P P-type ATPase
IOBPCOKE_01247 6.5e-54 arcA 3.5.3.6 E Arginine
IOBPCOKE_01248 3.2e-26 arcA 3.5.3.6 E Arginine
IOBPCOKE_01249 2.1e-157 lysR5 K LysR substrate binding domain
IOBPCOKE_01250 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
IOBPCOKE_01251 7.3e-86 3.4.21.96 S SLAP domain
IOBPCOKE_01252 2.3e-268 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOBPCOKE_01253 1.6e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IOBPCOKE_01254 9.5e-172 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IOBPCOKE_01255 3.7e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOBPCOKE_01256 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IOBPCOKE_01257 2.1e-120 srtA 3.4.22.70 M sortase family
IOBPCOKE_01258 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOBPCOKE_01259 7.6e-203 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOBPCOKE_01260 0.0 dnaK O Heat shock 70 kDa protein
IOBPCOKE_01261 3.3e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOBPCOKE_01262 1.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOBPCOKE_01263 3.3e-183 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IOBPCOKE_01264 8.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOBPCOKE_01265 3.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOBPCOKE_01266 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOBPCOKE_01267 1.2e-46 rplGA J ribosomal protein
IOBPCOKE_01268 3e-47 ylxR K Protein of unknown function (DUF448)
IOBPCOKE_01269 2.9e-197 nusA K Participates in both transcription termination and antitermination
IOBPCOKE_01270 3.2e-83 rimP J Required for maturation of 30S ribosomal subunits
IOBPCOKE_01271 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOBPCOKE_01272 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOBPCOKE_01273 5.2e-197 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IOBPCOKE_01274 1.6e-146 cdsA 2.7.7.41 I Belongs to the CDS family
IOBPCOKE_01275 3.5e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOBPCOKE_01276 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOBPCOKE_01277 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IOBPCOKE_01278 6.3e-185 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOBPCOKE_01279 1.6e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
IOBPCOKE_01280 2.5e-197 yabB 2.1.1.223 L Methyltransferase small domain
IOBPCOKE_01281 4.1e-115 plsC 2.3.1.51 I Acyltransferase
IOBPCOKE_01282 1e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IOBPCOKE_01283 0.0 pepO 3.4.24.71 O Peptidase family M13
IOBPCOKE_01284 2.9e-88 ycaM E amino acid
IOBPCOKE_01285 3.7e-123 ycaM E amino acid
IOBPCOKE_01286 5.6e-152 S haloacid dehalogenase-like hydrolase
IOBPCOKE_01287 0.0 S SH3-like domain
IOBPCOKE_01288 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOBPCOKE_01289 1.1e-170 whiA K May be required for sporulation
IOBPCOKE_01290 4.4e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IOBPCOKE_01291 1.4e-164 rapZ S Displays ATPase and GTPase activities
IOBPCOKE_01292 5.3e-82 S Short repeat of unknown function (DUF308)
IOBPCOKE_01293 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOBPCOKE_01294 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOBPCOKE_01295 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IOBPCOKE_01296 2.5e-67 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOBPCOKE_01297 1.5e-17 D nuclear chromosome segregation
IOBPCOKE_01299 1.3e-51
IOBPCOKE_01300 1.4e-195 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IOBPCOKE_01302 2.1e-66
IOBPCOKE_01306 4.2e-184 repB EP Plasmid replication protein
IOBPCOKE_01307 8.7e-27
IOBPCOKE_01308 4.6e-219 L Belongs to the 'phage' integrase family
IOBPCOKE_01309 6.5e-128 XK27_08435 K UTRA
IOBPCOKE_01310 1.6e-229 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IOBPCOKE_01311 8.3e-176 degV S DegV family
IOBPCOKE_01312 7.2e-146 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IOBPCOKE_01314 3.3e-37
IOBPCOKE_01315 2.2e-240 I Protein of unknown function (DUF2974)
IOBPCOKE_01316 2.4e-119 yhiD S MgtC family
IOBPCOKE_01319 4.3e-15 K Helix-turn-helix XRE-family like proteins
IOBPCOKE_01320 1.8e-64
IOBPCOKE_01321 3.1e-40
IOBPCOKE_01322 3.3e-36
IOBPCOKE_01323 3.7e-148 D Ftsk spoiiie family protein
IOBPCOKE_01324 1.4e-155 S Replication initiation factor
IOBPCOKE_01325 2.6e-59
IOBPCOKE_01326 4.4e-25
IOBPCOKE_01327 1.2e-224 L Belongs to the 'phage' integrase family
IOBPCOKE_01330 2e-33
IOBPCOKE_01332 3.9e-30 WQ51_00220 K Helix-turn-helix XRE-family like proteins
IOBPCOKE_01333 1.4e-113 ybbL S ABC transporter, ATP-binding protein
IOBPCOKE_01334 3e-131 ybbM S Uncharacterised protein family (UPF0014)
IOBPCOKE_01335 2.8e-38
IOBPCOKE_01336 2.8e-187 pipD E Dipeptidase
IOBPCOKE_01337 1.4e-68 pipD E Dipeptidase
IOBPCOKE_01338 8.8e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IOBPCOKE_01339 1.5e-168 hrtB V ABC transporter permease
IOBPCOKE_01340 3.5e-94 ygfC K Bacterial regulatory proteins, tetR family
IOBPCOKE_01341 1.2e-111 G phosphoglycerate mutase
IOBPCOKE_01342 4.4e-143 aroD S Alpha/beta hydrolase family
IOBPCOKE_01343 2.6e-143 S Belongs to the UPF0246 family
IOBPCOKE_01344 8.2e-122
IOBPCOKE_01345 1.1e-07
IOBPCOKE_01346 1.2e-170 dtpT U amino acid peptide transporter
IOBPCOKE_01347 1e-34 dtpT U amino acid peptide transporter
IOBPCOKE_01348 0.0 pepN 3.4.11.2 E aminopeptidase
IOBPCOKE_01349 5e-60 lysM M LysM domain
IOBPCOKE_01350 1.2e-172
IOBPCOKE_01351 1.1e-210 mdtG EGP Major facilitator Superfamily
IOBPCOKE_01352 8.8e-97 L DDE superfamily endonuclease
IOBPCOKE_01353 6.9e-147 L PFAM transposase, IS4 family protein
IOBPCOKE_01355 1.2e-152 malG P ABC transporter permease
IOBPCOKE_01356 2e-250 malF P Binding-protein-dependent transport system inner membrane component
IOBPCOKE_01357 1.6e-211 malE G Bacterial extracellular solute-binding protein
IOBPCOKE_01358 7e-206 msmX P Belongs to the ABC transporter superfamily
IOBPCOKE_01359 2.8e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IOBPCOKE_01360 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IOBPCOKE_01361 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
IOBPCOKE_01362 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
IOBPCOKE_01363 2.9e-46 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOBPCOKE_01364 2.7e-56 L Integrase
IOBPCOKE_01365 8e-244 slpX S SLAP domain
IOBPCOKE_01366 3.2e-127 K response regulator
IOBPCOKE_01367 4.6e-97 yceD S Uncharacterized ACR, COG1399
IOBPCOKE_01368 3.9e-215 ylbM S Belongs to the UPF0348 family
IOBPCOKE_01369 6.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOBPCOKE_01370 2.3e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IOBPCOKE_01371 1.5e-110 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOBPCOKE_01372 2.9e-212 yqeH S Ribosome biogenesis GTPase YqeH
IOBPCOKE_01373 1.3e-93 yqeG S HAD phosphatase, family IIIA
IOBPCOKE_01374 5.1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOBPCOKE_01375 6.2e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IOBPCOKE_01376 4.3e-56 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOBPCOKE_01377 6.9e-127 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
IOBPCOKE_01378 2.8e-82 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
IOBPCOKE_01379 2.5e-60 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
IOBPCOKE_01380 1e-184 S Domain of unknown function (DUF389)
IOBPCOKE_01381 1.1e-46 S ACT domain
IOBPCOKE_01382 2.9e-37
IOBPCOKE_01383 6e-91 4.1.1.44 S Carboxymuconolactone decarboxylase family
IOBPCOKE_01384 1.7e-32 4.1.1.44 S Carboxymuconolactone decarboxylase family
IOBPCOKE_01385 1.5e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOBPCOKE_01386 5e-98 S LPXTG cell wall anchor motif
IOBPCOKE_01387 8.7e-72
IOBPCOKE_01388 1e-102 yagE E amino acid
IOBPCOKE_01389 8.8e-47
IOBPCOKE_01390 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOBPCOKE_01391 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IOBPCOKE_01392 2.2e-241 cycA E Amino acid permease
IOBPCOKE_01393 1.6e-88 maa S transferase hexapeptide repeat
IOBPCOKE_01394 3.8e-148 K Transcriptional regulator
IOBPCOKE_01395 4.5e-54
IOBPCOKE_01396 9.5e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IOBPCOKE_01397 5.4e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOBPCOKE_01398 1.1e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOBPCOKE_01399 1.7e-276 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOBPCOKE_01400 7.4e-74 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IOBPCOKE_01401 7.8e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOBPCOKE_01402 1.1e-92 sigH K Belongs to the sigma-70 factor family
IOBPCOKE_01403 2.2e-34
IOBPCOKE_01404 6.6e-284 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IOBPCOKE_01405 7.1e-87 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOBPCOKE_01406 2.1e-48 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOBPCOKE_01407 5.8e-49 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOBPCOKE_01408 1.3e-96 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOBPCOKE_01409 5.9e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOBPCOKE_01410 8.1e-102 nusG K Participates in transcription elongation, termination and antitermination
IOBPCOKE_01411 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOBPCOKE_01412 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOBPCOKE_01414 1.4e-20 S DNA primase
IOBPCOKE_01415 1.7e-36
IOBPCOKE_01417 2.7e-17
IOBPCOKE_01418 4.8e-52 tnpR1 L Resolvase, N terminal domain
IOBPCOKE_01419 1.1e-46 tnpR1 L Resolvase, N terminal domain
IOBPCOKE_01420 3.9e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOBPCOKE_01421 2.1e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
IOBPCOKE_01422 1.9e-86
IOBPCOKE_01423 1.1e-72
IOBPCOKE_01424 3.5e-160 hlyX S Transporter associated domain
IOBPCOKE_01425 3.2e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IOBPCOKE_01426 1.8e-44 XK27_09445 S Domain of unknown function (DUF1827)
IOBPCOKE_01427 0.0 clpE O Belongs to the ClpA ClpB family
IOBPCOKE_01428 1.9e-47 cpdA S Calcineurin-like phosphoesterase
IOBPCOKE_01429 3.2e-10 cpdA S Calcineurin-like phosphoesterase
IOBPCOKE_01430 1.5e-219 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IOBPCOKE_01431 6.1e-70 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IOBPCOKE_01432 4.2e-106 ypsA S Belongs to the UPF0398 family
IOBPCOKE_01433 1.3e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IOBPCOKE_01434 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IOBPCOKE_01435 2.5e-112 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOBPCOKE_01436 7.4e-115 dnaD L DnaD domain protein
IOBPCOKE_01437 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IOBPCOKE_01438 2.9e-90 ypmB S Protein conserved in bacteria
IOBPCOKE_01439 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IOBPCOKE_01440 1e-215 ywhK S Membrane
IOBPCOKE_01441 2.2e-50
IOBPCOKE_01442 5.2e-19 S D-Ala-teichoic acid biosynthesis protein
IOBPCOKE_01443 3.6e-293 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOBPCOKE_01444 2.9e-240 dltB M MBOAT, membrane-bound O-acyltransferase family
IOBPCOKE_01445 5.7e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOBPCOKE_01446 3.5e-249 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IOBPCOKE_01447 3.2e-175 pbpX2 V Beta-lactamase
IOBPCOKE_01449 1.2e-10
IOBPCOKE_01450 8.7e-125 S CAAX protease self-immunity
IOBPCOKE_01451 4.1e-28
IOBPCOKE_01452 2.6e-49
IOBPCOKE_01453 3.5e-94 S Protein of unknown function (DUF975)
IOBPCOKE_01454 4e-145 lysA2 M Glycosyl hydrolases family 25
IOBPCOKE_01455 9.7e-289 ytgP S Polysaccharide biosynthesis protein
IOBPCOKE_01456 3e-37
IOBPCOKE_01457 1.4e-147 XK27_06780 V ABC transporter permease
IOBPCOKE_01458 2.3e-70 XK27_06780 V ABC transporter permease
IOBPCOKE_01459 2.1e-103 XK27_06780 V ABC transporter permease
IOBPCOKE_01460 3.9e-63 XK27_06785 V ABC transporter, ATP-binding protein
IOBPCOKE_01461 9.7e-22 XK27_06785 V ABC transporter, ATP-binding protein
IOBPCOKE_01462 8.7e-213 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOBPCOKE_01463 8.6e-173 S Alpha/beta hydrolase of unknown function (DUF915)
IOBPCOKE_01464 0.0 clpE O AAA domain (Cdc48 subfamily)
IOBPCOKE_01465 4.9e-119 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IOBPCOKE_01466 8.2e-129
IOBPCOKE_01467 9.1e-216 cycA E Amino acid permease
IOBPCOKE_01468 2.1e-244 yifK E Amino acid permease
IOBPCOKE_01469 1e-92 puuD S peptidase C26
IOBPCOKE_01470 1.8e-22 puuD S peptidase C26
IOBPCOKE_01471 3.5e-239 steT_1 E amino acid
IOBPCOKE_01472 2.7e-26
IOBPCOKE_01473 2.2e-35
IOBPCOKE_01474 1.2e-129 ecfA P ABC-type multidrug transport system ATPase component
IOBPCOKE_01475 6.6e-23
IOBPCOKE_01476 3e-150 noxC 1.5.1.39 C Nitroreductase
IOBPCOKE_01477 8e-185 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
IOBPCOKE_01478 3.5e-194 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
IOBPCOKE_01479 3.9e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
IOBPCOKE_01480 9e-203 4.2.1.126 S Bacterial protein of unknown function (DUF871)
IOBPCOKE_01483 4.7e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOBPCOKE_01484 7.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOBPCOKE_01485 1.4e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IOBPCOKE_01486 6.1e-58
IOBPCOKE_01487 1.9e-83
IOBPCOKE_01488 2e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
IOBPCOKE_01489 2.9e-177 K AI-2E family transporter
IOBPCOKE_01490 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
IOBPCOKE_01491 2.1e-67 S Domain of unknown function (DUF4430)
IOBPCOKE_01492 2.4e-87 S ECF transporter, substrate-specific component
IOBPCOKE_01493 1.3e-99 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
IOBPCOKE_01494 1.6e-148 S Putative ABC-transporter type IV
IOBPCOKE_01495 2.2e-233 S LPXTG cell wall anchor motif
IOBPCOKE_01496 7.9e-155 pipD E Dipeptidase
IOBPCOKE_01497 3.5e-39 pipD E Dipeptidase
IOBPCOKE_01498 1.3e-254 V Restriction endonuclease
IOBPCOKE_01499 2.8e-105 K Bacterial regulatory proteins, tetR family
IOBPCOKE_01500 8e-24 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IOBPCOKE_01501 5.6e-142 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IOBPCOKE_01503 8.5e-170 psaA P Belongs to the bacterial solute-binding protein 9 family
IOBPCOKE_01506 9.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOBPCOKE_01507 4.4e-264 qacA EGP Major facilitator Superfamily
IOBPCOKE_01508 3.1e-72 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IOBPCOKE_01509 2.7e-62 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IOBPCOKE_01510 6e-120 3.6.1.27 I Acid phosphatase homologues
IOBPCOKE_01511 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOBPCOKE_01512 2e-297 ytgP S Polysaccharide biosynthesis protein
IOBPCOKE_01513 1.5e-20 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
IOBPCOKE_01514 4.9e-88 O Belongs to the peptidase S8 family
IOBPCOKE_01515 3.2e-64 O Belongs to the peptidase S8 family
IOBPCOKE_01516 1.5e-95 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
IOBPCOKE_01517 2.2e-52 P secondary active sulfate transmembrane transporter activity
IOBPCOKE_01518 3.1e-108 P secondary active sulfate transmembrane transporter activity
IOBPCOKE_01519 2.6e-123 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
IOBPCOKE_01520 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IOBPCOKE_01521 5.7e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOBPCOKE_01522 8.9e-221 EGP Major facilitator Superfamily
IOBPCOKE_01523 1.4e-99 ropB K Transcriptional regulator
IOBPCOKE_01524 7.3e-49 L Winged helix-turn helix
IOBPCOKE_01525 1.2e-93 L Psort location Cytoplasmic, score 8.87
IOBPCOKE_01528 7e-197 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IOBPCOKE_01529 4.3e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IOBPCOKE_01530 2.3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IOBPCOKE_01532 3.7e-105 Q Imidazolonepropionase and related amidohydrolases
IOBPCOKE_01533 8.9e-118 Q Imidazolonepropionase and related amidohydrolases
IOBPCOKE_01534 4.5e-239 oppA E ABC transporter
IOBPCOKE_01535 1e-25 oppA E ABC transporter
IOBPCOKE_01536 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
IOBPCOKE_01537 6.1e-219 naiP EGP Major facilitator Superfamily
IOBPCOKE_01538 5.3e-07 S ParE toxin of type II toxin-antitoxin system, parDE
IOBPCOKE_01539 1.9e-37 mta K helix_turn_helix, mercury resistance
IOBPCOKE_01540 8.3e-93 yyaR K Acetyltransferase (GNAT) domain
IOBPCOKE_01541 0.0 uvrA3 L excinuclease ABC, A subunit
IOBPCOKE_01544 2.1e-103 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
IOBPCOKE_01545 6.6e-75 K LytTr DNA-binding domain
IOBPCOKE_01546 1.9e-74 S Protein of unknown function (DUF3021)
IOBPCOKE_01547 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IOBPCOKE_01548 1.5e-17
IOBPCOKE_01549 6.9e-289 lsa S ABC transporter
IOBPCOKE_01550 8.2e-154 ykuT M mechanosensitive ion channel
IOBPCOKE_01551 3.3e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IOBPCOKE_01552 4.7e-39
IOBPCOKE_01553 4.4e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IOBPCOKE_01554 8.3e-182 ccpA K catabolite control protein A
IOBPCOKE_01555 2.6e-266 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IOBPCOKE_01556 1.1e-55
IOBPCOKE_01557 3.9e-278 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IOBPCOKE_01558 3e-89 yutD S Protein of unknown function (DUF1027)
IOBPCOKE_01559 1.2e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IOBPCOKE_01560 1.9e-83 S Protein of unknown function (DUF1461)
IOBPCOKE_01561 1.8e-116 dedA S SNARE-like domain protein
IOBPCOKE_01562 2.5e-152 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
IOBPCOKE_01563 1.1e-95
IOBPCOKE_01564 3.8e-18
IOBPCOKE_01565 1.9e-12
IOBPCOKE_01566 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOBPCOKE_01567 1.5e-166 dnaI L Primosomal protein DnaI
IOBPCOKE_01568 8.9e-248 dnaB L Replication initiation and membrane attachment
IOBPCOKE_01569 4.1e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOBPCOKE_01570 1.5e-106 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOBPCOKE_01571 1.6e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IOBPCOKE_01572 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOBPCOKE_01573 2e-140 pnuC H nicotinamide mononucleotide transporter
IOBPCOKE_01574 2.4e-11
IOBPCOKE_01575 8.4e-277 V ABC transporter transmembrane region
IOBPCOKE_01576 1.2e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IOBPCOKE_01577 1.3e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IOBPCOKE_01578 1.3e-95 F Nucleoside 2-deoxyribosyltransferase
IOBPCOKE_01579 7.1e-57 S Peptidase propeptide and YPEB domain
IOBPCOKE_01580 9e-87 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
IOBPCOKE_01581 2.8e-47 yybA 2.3.1.57 K Transcriptional regulator
IOBPCOKE_01582 1.3e-142 G Bacterial extracellular solute-binding protein
IOBPCOKE_01583 3.7e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOBPCOKE_01584 4.6e-171 coaA 2.7.1.33 F Pantothenic acid kinase
IOBPCOKE_01585 1.3e-104 E GDSL-like Lipase/Acylhydrolase
IOBPCOKE_01586 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IOBPCOKE_01587 1.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IOBPCOKE_01588 3.2e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOBPCOKE_01589 9.4e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IOBPCOKE_01590 3.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOBPCOKE_01591 2.2e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOBPCOKE_01592 5.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IOBPCOKE_01593 1e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOBPCOKE_01594 1.2e-32 S RelB antitoxin
IOBPCOKE_01595 2.2e-58 hsdS 3.1.21.3 L PFAM restriction modification system DNA specificity domain
IOBPCOKE_01596 1.2e-39 3.1.21.3 V Type I restriction modification DNA specificity domain
IOBPCOKE_01597 2.2e-276 hsdM 2.1.1.72 V type I restriction-modification system
IOBPCOKE_01598 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
IOBPCOKE_01599 2.5e-227 S response to antibiotic
IOBPCOKE_01600 8.2e-93
IOBPCOKE_01601 1.3e-25
IOBPCOKE_01602 1.7e-104
IOBPCOKE_01603 4.7e-176 lacX 5.1.3.3 G Aldose 1-epimerase
IOBPCOKE_01604 2.2e-233 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IOBPCOKE_01605 3e-90 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IOBPCOKE_01606 1.3e-168 xerC D Phage integrase, N-terminal SAM-like domain
IOBPCOKE_01607 9.4e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IOBPCOKE_01608 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOBPCOKE_01609 1.1e-155 dprA LU DNA protecting protein DprA
IOBPCOKE_01610 3.7e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOBPCOKE_01611 1.3e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IOBPCOKE_01612 3.1e-279 yjcE P Sodium proton antiporter
IOBPCOKE_01613 9.3e-36 yozE S Belongs to the UPF0346 family
IOBPCOKE_01614 7.7e-149 DegV S Uncharacterised protein, DegV family COG1307
IOBPCOKE_01615 6.7e-114 hlyIII S protein, hemolysin III
IOBPCOKE_01616 7.8e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IOBPCOKE_01617 4.2e-161 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOBPCOKE_01618 2.7e-230 S Tetratricopeptide repeat protein
IOBPCOKE_01619 3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IOBPCOKE_01620 1.8e-178 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IOBPCOKE_01621 4.3e-209 rpsA 1.17.7.4 J Ribosomal protein S1
IOBPCOKE_01622 3.5e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IOBPCOKE_01623 5.3e-30 yocH M Lysin motif
IOBPCOKE_01624 1.5e-119 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOBPCOKE_01625 8.5e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IOBPCOKE_01626 9.2e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOBPCOKE_01627 2.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOBPCOKE_01628 4.9e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOBPCOKE_01629 4e-167 xerD D recombinase XerD
IOBPCOKE_01630 6.5e-170 cvfB S S1 domain
IOBPCOKE_01631 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IOBPCOKE_01632 6.6e-184 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IOBPCOKE_01633 0.0 dnaE 2.7.7.7 L DNA polymerase
IOBPCOKE_01634 2.5e-22 S Protein of unknown function (DUF2929)
IOBPCOKE_01635 2.1e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IOBPCOKE_01636 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IOBPCOKE_01637 6.2e-33 yrvD S Lipopolysaccharide assembly protein A domain
IOBPCOKE_01638 5.5e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IOBPCOKE_01639 2.4e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IOBPCOKE_01640 0.0 oatA I Acyltransferase
IOBPCOKE_01641 1.4e-242 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOBPCOKE_01642 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOBPCOKE_01644 3.8e-08 L Transposase
IOBPCOKE_01645 2e-166 S SLAP domain
IOBPCOKE_01646 1.5e-135
IOBPCOKE_01647 3.9e-196 S SLAP domain
IOBPCOKE_01648 5.6e-146 arbV 2.3.1.51 I Acyl-transferase
IOBPCOKE_01649 2.5e-65
IOBPCOKE_01650 1.2e-146 K Helix-turn-helix domain
IOBPCOKE_01651 4.1e-158 arbx M Glycosyl transferase family 8
IOBPCOKE_01652 3.1e-186 arbY M Glycosyl transferase family 8
IOBPCOKE_01653 3.7e-10 arbY M Glycosyl transferase family 8
IOBPCOKE_01654 5.9e-157 arbY M Glycosyl transferase family 8
IOBPCOKE_01655 2.3e-167 arbZ I Phosphate acyltransferases
IOBPCOKE_01656 1.3e-34 S Cytochrome b5
IOBPCOKE_01657 2.3e-102
IOBPCOKE_01658 4.2e-26 M LysM domain
IOBPCOKE_01659 2.9e-35 M LysM domain
IOBPCOKE_01661 3e-07 S protein conserved in bacteria
IOBPCOKE_01662 6e-76 S Psort location Cytoplasmic, score
IOBPCOKE_01663 2.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IOBPCOKE_01664 8.7e-176 S SLAP domain
IOBPCOKE_01665 1.8e-289 M Peptidase family M1 domain
IOBPCOKE_01666 2.9e-195 S Bacteriocin helveticin-J
IOBPCOKE_01667 7e-14
IOBPCOKE_01668 4.3e-52 L RelB antitoxin
IOBPCOKE_01669 1.3e-141 qmcA O prohibitin homologues
IOBPCOKE_01670 7.5e-123 darA C Flavodoxin
IOBPCOKE_01671 1.5e-210 S SLAP domain
IOBPCOKE_01672 1.4e-16 S Protein of unknown function (DUF2922)
IOBPCOKE_01673 7.1e-30
IOBPCOKE_01675 2.5e-74
IOBPCOKE_01676 0.0 kup P Transport of potassium into the cell
IOBPCOKE_01677 0.0 pepO 3.4.24.71 O Peptidase family M13
IOBPCOKE_01678 7.9e-227 yttB EGP Major facilitator Superfamily
IOBPCOKE_01679 3.3e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOBPCOKE_01680 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
IOBPCOKE_01681 1.5e-59
IOBPCOKE_01682 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOBPCOKE_01683 5.1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOBPCOKE_01684 3.1e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
IOBPCOKE_01685 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IOBPCOKE_01686 4.7e-224 patA 2.6.1.1 E Aminotransferase
IOBPCOKE_01687 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IOBPCOKE_01688 3.8e-134 glcR K DeoR C terminal sensor domain
IOBPCOKE_01689 2.9e-63 S Enterocin A Immunity
IOBPCOKE_01690 2.5e-55 yitW S Iron-sulfur cluster assembly protein
IOBPCOKE_01691 1.4e-272 sufB O assembly protein SufB
IOBPCOKE_01692 3.8e-81 nifU C SUF system FeS assembly protein, NifU family
IOBPCOKE_01693 1.5e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOBPCOKE_01694 2.3e-229 sufD O FeS assembly protein SufD
IOBPCOKE_01695 3.4e-146 sufC O FeS assembly ATPase SufC
IOBPCOKE_01696 3.9e-84 S Aminoacyl-tRNA editing domain
IOBPCOKE_01697 6.7e-152 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOBPCOKE_01698 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IOBPCOKE_01699 5.1e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOBPCOKE_01700 3.6e-63 yodB K Transcriptional regulator, HxlR family
IOBPCOKE_01701 1.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOBPCOKE_01702 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOBPCOKE_01703 8.3e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOBPCOKE_01704 8.7e-170 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
IOBPCOKE_01705 1.3e-56 S Phage derived protein Gp49-like (DUF891)
IOBPCOKE_01706 2.4e-38 K Helix-turn-helix domain
IOBPCOKE_01707 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IOBPCOKE_01708 9.5e-80 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOBPCOKE_01709 1.5e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOBPCOKE_01710 2.1e-199 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IOBPCOKE_01711 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
IOBPCOKE_01712 0.0 FbpA K Fibronectin-binding protein
IOBPCOKE_01716 4.8e-221 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
IOBPCOKE_01717 8.9e-203 cpoA GT4 M Glycosyltransferase, group 1 family protein
IOBPCOKE_01718 3.3e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOBPCOKE_01719 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOBPCOKE_01720 2.3e-29 secG U Preprotein translocase
IOBPCOKE_01721 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IOBPCOKE_01722 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IOBPCOKE_01723 3.7e-66 S ASCH domain
IOBPCOKE_01724 1.8e-167 L restriction endonuclease
IOBPCOKE_01725 2.5e-155 L helicase
IOBPCOKE_01726 6e-302 hsdM 2.1.1.72 V type I restriction-modification system
IOBPCOKE_01727 4.1e-98 3.1.21.3 V Type I restriction modification DNA specificity domain
IOBPCOKE_01728 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IOBPCOKE_01730 1.5e-63 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IOBPCOKE_01731 4.2e-81 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IOBPCOKE_01732 2.3e-99 3.6.1.27 I Acid phosphatase homologues
IOBPCOKE_01733 2.3e-91 yitS S Uncharacterised protein, DegV family COG1307
IOBPCOKE_01734 3.4e-29 yitS S Uncharacterised protein, DegV family COG1307
IOBPCOKE_01735 3.6e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOBPCOKE_01737 1.6e-85 C nitroreductase
IOBPCOKE_01738 7.7e-11 ypbG 2.7.1.2 GK ROK family
IOBPCOKE_01739 7e-81 ypbG 2.7.1.2 GK ROK family
IOBPCOKE_01740 2.8e-281 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOBPCOKE_01741 1.1e-135 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOBPCOKE_01742 3e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IOBPCOKE_01743 2.7e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOBPCOKE_01744 2e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IOBPCOKE_01745 6.8e-25
IOBPCOKE_01746 2.3e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOBPCOKE_01747 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOBPCOKE_01748 2.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOBPCOKE_01749 2.6e-134 comFC S Competence protein
IOBPCOKE_01750 1.1e-247 comFA L Helicase C-terminal domain protein
IOBPCOKE_01751 2.1e-117 yvyE 3.4.13.9 S YigZ family
IOBPCOKE_01752 1.4e-209 tagO 2.7.8.33, 2.7.8.35 M transferase
IOBPCOKE_01753 3.6e-219 rny S Endoribonuclease that initiates mRNA decay
IOBPCOKE_01754 7.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOBPCOKE_01755 1.9e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOBPCOKE_01756 6.8e-132 ymfM S Helix-turn-helix domain
IOBPCOKE_01757 1e-133 IQ Enoyl-(Acyl carrier protein) reductase
IOBPCOKE_01758 1e-237 S Peptidase M16
IOBPCOKE_01759 3.5e-227 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
IOBPCOKE_01760 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IOBPCOKE_01761 1.4e-68 WQ51_03320 S Protein of unknown function (DUF1149)
IOBPCOKE_01762 5.5e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOBPCOKE_01763 4.9e-213 yubA S AI-2E family transporter
IOBPCOKE_01764 8.7e-35 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IOBPCOKE_01765 1.6e-22 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IOBPCOKE_01766 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
IOBPCOKE_01767 8.8e-203 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IOBPCOKE_01768 3.5e-110 S SNARE associated Golgi protein
IOBPCOKE_01769 3e-57 mycA 4.2.1.53 S Myosin-crossreactive antigen
IOBPCOKE_01770 9.8e-227 mycA 4.2.1.53 S Myosin-crossreactive antigen
IOBPCOKE_01771 7.9e-10 mycA 4.2.1.53 S Myosin-crossreactive antigen
IOBPCOKE_01772 3.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOBPCOKE_01773 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOBPCOKE_01774 2.1e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
IOBPCOKE_01775 2.3e-113 yjbK S CYTH
IOBPCOKE_01776 1e-113 yjbH Q Thioredoxin
IOBPCOKE_01777 2.7e-160 coiA 3.6.4.12 S Competence protein
IOBPCOKE_01778 1.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IOBPCOKE_01779 7.9e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IOBPCOKE_01780 1.4e-306 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOBPCOKE_01781 1.1e-40 ptsH G phosphocarrier protein HPR
IOBPCOKE_01782 4.1e-26
IOBPCOKE_01783 1.5e-169 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
IOBPCOKE_01784 0.0 S membrane
IOBPCOKE_01785 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IOBPCOKE_01786 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IOBPCOKE_01787 4.9e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IOBPCOKE_01788 6.8e-119 gluP 3.4.21.105 S Rhomboid family
IOBPCOKE_01789 3.3e-33 yqgQ S Bacterial protein of unknown function (DUF910)
IOBPCOKE_01790 4.5e-70 yqhL P Rhodanese-like protein
IOBPCOKE_01791 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOBPCOKE_01792 2.7e-20 G Glycosyl hydrolases family 8
IOBPCOKE_01793 2.5e-64 G Glycosyl hydrolases family 8
IOBPCOKE_01794 9.5e-18 S Peptidase propeptide and YPEB domain
IOBPCOKE_01796 1.7e-122 yfbR S HD containing hydrolase-like enzyme
IOBPCOKE_01797 2.4e-161 L HNH nucleases
IOBPCOKE_01798 3.3e-138 glnQ E ABC transporter, ATP-binding protein
IOBPCOKE_01799 5.5e-292 glnP P ABC transporter permease
IOBPCOKE_01800 2.5e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IOBPCOKE_01801 8.2e-63 yeaO S Protein of unknown function, DUF488
IOBPCOKE_01802 3.8e-121 terC P Integral membrane protein TerC family
IOBPCOKE_01803 7.5e-94 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
IOBPCOKE_01804 9.7e-64 cobB K SIR2 family
IOBPCOKE_01805 1.8e-49 cas4 3.1.12.1 L Domain of unknown function DUF83
IOBPCOKE_01806 1.5e-181 cas3 L CRISPR-associated helicase cas3
IOBPCOKE_01807 1.1e-66 cas5t L CRISPR-associated protein Cas5
IOBPCOKE_01808 1.3e-104 cst2 L CRISPR-associated negative auto-regulator DevR/Csa2
IOBPCOKE_01809 2e-106 cst1 S CRISPR-associated protein (Cas_CXXC_CXXC)
IOBPCOKE_01810 4e-43 cas6 L CRISPR associated protein Cas6
IOBPCOKE_01811 2.8e-66 purD 6.3.4.13 F Belongs to the GARS family
IOBPCOKE_01812 2e-55 purD 6.3.4.13 F Belongs to the GARS family
IOBPCOKE_01813 2.9e-66 yfjM S Protein of unknown function DUF262
IOBPCOKE_01814 7.2e-303 XK27_11280 S Psort location CytoplasmicMembrane, score
IOBPCOKE_01815 1.2e-155 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOBPCOKE_01816 0.0 pepO 3.4.24.71 O Peptidase family M13
IOBPCOKE_01817 2.3e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
IOBPCOKE_01818 8.1e-233 steT E amino acid
IOBPCOKE_01820 1.4e-190 tcsA S ABC transporter substrate-binding protein PnrA-like
IOBPCOKE_01821 7.3e-286 xylG 3.6.3.17 S ABC transporter
IOBPCOKE_01822 1.9e-201 yufP S Belongs to the binding-protein-dependent transport system permease family
IOBPCOKE_01823 4.7e-166 yufQ S Belongs to the binding-protein-dependent transport system permease family
IOBPCOKE_01824 3e-105 K SIS domain
IOBPCOKE_01825 1.7e-61 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
IOBPCOKE_01826 2.6e-91 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
IOBPCOKE_01827 5.5e-97 yxkA S Phosphatidylethanolamine-binding protein
IOBPCOKE_01828 2e-247 yjjP S Putative threonine/serine exporter
IOBPCOKE_01829 8.8e-27 citR K Putative sugar-binding domain
IOBPCOKE_01830 7e-44 citR K Putative sugar-binding domain
IOBPCOKE_01831 1.8e-50 citR K Putative sugar-binding domain
IOBPCOKE_01832 3.8e-54
IOBPCOKE_01833 4.7e-16
IOBPCOKE_01834 2.2e-66 S Domain of unknown function DUF1828
IOBPCOKE_01835 5.6e-95 S UPF0397 protein
IOBPCOKE_01836 2.3e-262 ykoD P ABC transporter, ATP-binding protein
IOBPCOKE_01837 1.2e-36 ykoD P ABC transporter, ATP-binding protein
IOBPCOKE_01838 7.3e-147 cbiQ P cobalt transport
IOBPCOKE_01839 4.6e-10
IOBPCOKE_01840 8.7e-70 yeaL S Protein of unknown function (DUF441)
IOBPCOKE_01841 7e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOBPCOKE_01842 1.5e-270 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOBPCOKE_01843 1.3e-151
IOBPCOKE_01844 3.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOBPCOKE_01845 3.3e-205 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOBPCOKE_01846 5.7e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOBPCOKE_01847 1.3e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
IOBPCOKE_01848 7.8e-182 P ABC transporter
IOBPCOKE_01849 5.7e-201 V ABC-type multidrug transport system, ATPase and permease components
IOBPCOKE_01850 5.8e-54 S ABC transporter
IOBPCOKE_01851 1.7e-14
IOBPCOKE_01852 7.7e-40 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
IOBPCOKE_01853 3e-90 S VanZ like family
IOBPCOKE_01854 8.9e-133 yebC K Transcriptional regulatory protein
IOBPCOKE_01855 6e-177 comGA NU Type II IV secretion system protein
IOBPCOKE_01856 6.4e-174 comGB NU type II secretion system
IOBPCOKE_01857 3.7e-44 comGC U competence protein ComGC
IOBPCOKE_01858 2.1e-73
IOBPCOKE_01859 3.9e-41
IOBPCOKE_01860 4.2e-81 comGF U Putative Competence protein ComGF
IOBPCOKE_01861 7.8e-188 ytxK 2.1.1.72 L N-6 DNA Methylase
IOBPCOKE_01862 5.5e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOBPCOKE_01864 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOBPCOKE_01865 1.2e-73 nrdI F Probably involved in ribonucleotide reductase function
IOBPCOKE_01866 7.3e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOBPCOKE_01867 9.1e-42 IQ reductase
IOBPCOKE_01868 3.3e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
IOBPCOKE_01869 2.7e-219 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IOBPCOKE_01870 3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IOBPCOKE_01871 1.6e-67
IOBPCOKE_01872 8.4e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOBPCOKE_01873 2.9e-104 S Peptidase family M23
IOBPCOKE_01874 2e-152 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IOBPCOKE_01875 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IOBPCOKE_01876 1.5e-69 yqeY S YqeY-like protein
IOBPCOKE_01877 2.9e-176 phoH T phosphate starvation-inducible protein PhoH
IOBPCOKE_01878 1.7e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOBPCOKE_01879 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOBPCOKE_01880 1e-136 recO L Involved in DNA repair and RecF pathway recombination
IOBPCOKE_01881 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IOBPCOKE_01882 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IOBPCOKE_01883 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOBPCOKE_01884 6.4e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOBPCOKE_01885 2.1e-125 S Peptidase family M23
IOBPCOKE_01886 6e-31 mutT 3.6.1.55 F NUDIX domain
IOBPCOKE_01887 7.6e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
IOBPCOKE_01888 2.2e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IOBPCOKE_01889 1.4e-242 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IOBPCOKE_01890 5e-60 yvoA_1 K Transcriptional regulator, GntR family
IOBPCOKE_01891 2.8e-123 skfE V ATPases associated with a variety of cellular activities
IOBPCOKE_01892 3.5e-149
IOBPCOKE_01893 4.2e-116
IOBPCOKE_01894 1.8e-253 rarA L recombination factor protein RarA
IOBPCOKE_01895 7.8e-28
IOBPCOKE_01896 7.2e-106 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IOBPCOKE_01897 8.1e-87
IOBPCOKE_01898 4.7e-177
IOBPCOKE_01899 4.3e-261 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
IOBPCOKE_01900 5.7e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IOBPCOKE_01901 1.9e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IOBPCOKE_01902 3.4e-180 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IOBPCOKE_01903 1.6e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
IOBPCOKE_01904 4.2e-119 L Transposase
IOBPCOKE_01905 2.1e-62 L Transposase
IOBPCOKE_01906 3.2e-59 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IOBPCOKE_01910 3.2e-118 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IOBPCOKE_01911 2.8e-42 V ABC transporter transmembrane region
IOBPCOKE_01912 1e-133 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IOBPCOKE_01913 2.9e-229 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
IOBPCOKE_01914 4.9e-110 G Phosphoglycerate mutase family
IOBPCOKE_01915 4.6e-188 D nuclear chromosome segregation
IOBPCOKE_01916 6.8e-66 M LysM domain protein
IOBPCOKE_01917 5.6e-13
IOBPCOKE_01918 7.1e-25 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
IOBPCOKE_01919 3.3e-95 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
IOBPCOKE_01920 2.1e-67
IOBPCOKE_01921 7.1e-32
IOBPCOKE_01922 3.1e-71 S Iron-sulphur cluster biosynthesis
IOBPCOKE_01924 3.3e-86 D CobQ CobB MinD ParA nucleotide binding domain protein
IOBPCOKE_01925 2.7e-08
IOBPCOKE_01926 1.8e-27 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IOBPCOKE_01927 6.6e-21 L Transposase
IOBPCOKE_01928 2e-18 spaB S Lantibiotic biosynthesis dehydratase C-term
IOBPCOKE_01929 8.9e-25 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
IOBPCOKE_01932 5e-22 K DNA-templated transcription, initiation
IOBPCOKE_01933 2.3e-226 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOBPCOKE_01934 3e-209 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
IOBPCOKE_01935 0.0 yjbQ P TrkA C-terminal domain protein
IOBPCOKE_01936 1.4e-133 gepA K Protein of unknown function (DUF4065)
IOBPCOKE_01937 2.3e-53 trxA O Belongs to the thioredoxin family
IOBPCOKE_01938 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IOBPCOKE_01939 8.1e-51 yrzB S Belongs to the UPF0473 family
IOBPCOKE_01940 1e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOBPCOKE_01941 2e-42 yrzL S Belongs to the UPF0297 family
IOBPCOKE_01942 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOBPCOKE_01943 4.3e-52
IOBPCOKE_01944 6.2e-154 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
IOBPCOKE_01945 1.7e-202 yceI EGP Major facilitator Superfamily
IOBPCOKE_01946 3.4e-118 L Transposase and inactivated derivatives, IS30 family
IOBPCOKE_01947 2.8e-67 K Acetyltransferase (GNAT) domain
IOBPCOKE_01949 1.6e-222 oxlT P Major Facilitator Superfamily
IOBPCOKE_01950 2.9e-22 L Helix-turn-helix domain
IOBPCOKE_01951 1.4e-55 L Probable transposase
IOBPCOKE_01952 8.9e-45 L Probable transposase
IOBPCOKE_01953 1.6e-54 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IOBPCOKE_01954 5.3e-43
IOBPCOKE_01955 1.5e-40 K Helix-turn-helix XRE-family like proteins
IOBPCOKE_01956 3.3e-14 S Phage derived protein Gp49-like (DUF891)
IOBPCOKE_01957 1.2e-08
IOBPCOKE_01958 5.7e-16 L PFAM IS66 Orf2 family protein
IOBPCOKE_01960 4.3e-289 V ABC-type multidrug transport system, ATPase and permease components
IOBPCOKE_01961 1.2e-188 yfjM S Protein of unknown function DUF262
IOBPCOKE_01962 3.2e-50 S Archaea bacterial proteins of unknown function
IOBPCOKE_01963 1.1e-28
IOBPCOKE_01964 6.9e-63 L transposase, IS605 OrfB family
IOBPCOKE_01965 6.9e-60 L transposase, IS605 OrfB family
IOBPCOKE_01966 3.3e-83 S An automated process has identified a potential problem with this gene model
IOBPCOKE_01967 2.9e-140 S Protein of unknown function (DUF3100)
IOBPCOKE_01968 2.1e-246 3.5.1.47 S Peptidase dimerisation domain
IOBPCOKE_01969 9.1e-158 S Sucrose-6F-phosphate phosphohydrolase
IOBPCOKE_01970 1.9e-39 rpmE2 J Ribosomal protein L31
IOBPCOKE_01971 5.3e-264 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOBPCOKE_01972 8.5e-255 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IOBPCOKE_01973 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOBPCOKE_01974 2e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOBPCOKE_01975 2.7e-18 K transcriptional regulator
IOBPCOKE_01976 1.3e-64 K transcriptional regulator
IOBPCOKE_01977 6.2e-108 dedA 3.1.3.1 S SNARE associated Golgi protein
IOBPCOKE_01978 9e-251 yfnA E Amino Acid
IOBPCOKE_01979 3.3e-43 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOBPCOKE_01980 2.1e-33 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOBPCOKE_01981 7.8e-16 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOBPCOKE_01982 4.8e-45 yxeH S hydrolase
IOBPCOKE_01983 2.2e-85 yxeH S hydrolase
IOBPCOKE_01984 5.6e-155 S reductase
IOBPCOKE_01985 9.2e-220 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IOBPCOKE_01986 4.9e-61 yoaK S Protein of unknown function (DUF1275)
IOBPCOKE_01987 2.2e-23 yoaK S Protein of unknown function (DUF1275)
IOBPCOKE_01988 1.8e-54 K Helix-turn-helix domain
IOBPCOKE_01989 5.9e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOBPCOKE_01990 1.1e-164 ppaC 3.6.1.1 C inorganic pyrophosphatase
IOBPCOKE_01991 2.9e-171 K Transcriptional regulator
IOBPCOKE_01992 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOBPCOKE_01993 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOBPCOKE_01994 6.5e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOBPCOKE_01995 1.1e-199 snf 2.7.11.1 KL domain protein
IOBPCOKE_01996 1.2e-85 dps P Belongs to the Dps family
IOBPCOKE_01997 7.6e-94 K acetyltransferase
IOBPCOKE_01998 9.4e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
IOBPCOKE_01999 9.5e-94 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IOBPCOKE_02000 4.3e-109 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IOBPCOKE_02001 1.9e-09 1.1.1.3 T phosphoserine phosphatase activity
IOBPCOKE_02002 8.8e-29 1.1.1.3 T phosphoserine phosphatase activity
IOBPCOKE_02003 1.7e-142 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IOBPCOKE_02004 2.1e-39 S Hydrolases of the alpha beta superfamily
IOBPCOKE_02005 6.1e-18 S Hydrolases of the alpha beta superfamily
IOBPCOKE_02006 1e-57 S Alpha beta hydrolase
IOBPCOKE_02007 7.4e-61 K Acetyltransferase (GNAT) family
IOBPCOKE_02008 1.8e-127 gor 1.8.1.7 C Glutathione reductase
IOBPCOKE_02010 1.3e-116 L Integrase
IOBPCOKE_02011 1.7e-90 dam 2.1.1.72 H Site-specific DNA-methyltransferase (adenine-specific)
IOBPCOKE_02012 6.3e-145 L hmm pf00665
IOBPCOKE_02013 1.7e-42 L Helix-turn-helix domain
IOBPCOKE_02014 3.3e-48 L Helix-turn-helix domain
IOBPCOKE_02015 2.7e-160 cjaA ET ABC transporter substrate-binding protein
IOBPCOKE_02016 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOBPCOKE_02017 4e-79 P ABC transporter permease
IOBPCOKE_02018 6e-112 papP P ABC transporter, permease protein
IOBPCOKE_02019 3.4e-25 S Uncharacterized protein conserved in bacteria (DUF2255)
IOBPCOKE_02020 1.5e-48 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
IOBPCOKE_02021 2.6e-97 3.6.1.55, 3.6.1.67 F NUDIX domain
IOBPCOKE_02022 1e-201 folP 2.5.1.15 H dihydropteroate synthase
IOBPCOKE_02023 7.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IOBPCOKE_02024 1.1e-200 folE 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 F GTP cyclohydrolase 1
IOBPCOKE_02025 6.5e-57 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IOBPCOKE_02026 8e-125 magIII L Base excision DNA repair protein, HhH-GPD family
IOBPCOKE_02027 2.1e-42
IOBPCOKE_02028 1.9e-74 gntR K UbiC transcription regulator-associated domain protein
IOBPCOKE_02029 2.2e-20 gntR K UbiC transcription regulator-associated domain protein
IOBPCOKE_02030 4.8e-176 rihB 3.2.2.1 F Nucleoside
IOBPCOKE_02031 0.0 kup P Transport of potassium into the cell
IOBPCOKE_02032 5.3e-127 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IOBPCOKE_02033 9.2e-167 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOBPCOKE_02034 2.6e-162 2.7.7.12 C Domain of unknown function (DUF4931)
IOBPCOKE_02035 4.4e-213 lacZ 3.2.1.23 G -beta-galactosidase
IOBPCOKE_02036 0.0 lacS G Transporter
IOBPCOKE_02037 4e-57 lacS G Transporter
IOBPCOKE_02038 1.8e-71 lacS G Transporter
IOBPCOKE_02039 1.2e-47 lacS G Transporter
IOBPCOKE_02040 1.9e-24 lacS G Transporter
IOBPCOKE_02041 1.4e-189 lacR K Transcriptional regulator
IOBPCOKE_02042 4.9e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IOBPCOKE_02043 7.2e-42 K Helix-turn-helix XRE-family like proteins
IOBPCOKE_02044 3.3e-56
IOBPCOKE_02045 3.8e-20
IOBPCOKE_02046 1.1e-89
IOBPCOKE_02047 3.4e-130 K Helix-turn-helix XRE-family like proteins
IOBPCOKE_02048 6.6e-251 S SLAP domain
IOBPCOKE_02049 3.3e-78 pssE S Glycosyltransferase family 28 C-terminal domain
IOBPCOKE_02050 9.8e-82 cpsF M Oligosaccharide biosynthesis protein Alg14 like
IOBPCOKE_02051 1.2e-120 rfbP M Bacterial sugar transferase
IOBPCOKE_02052 2.8e-145 ywqE 3.1.3.48 GM PHP domain protein
IOBPCOKE_02053 1.2e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IOBPCOKE_02054 3.2e-145 epsB M biosynthesis protein
IOBPCOKE_02055 1.8e-179 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOBPCOKE_02056 1.2e-57 V efflux transmembrane transporter activity
IOBPCOKE_02057 0.0 O Belongs to the peptidase S8 family
IOBPCOKE_02058 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
IOBPCOKE_02059 7.9e-55
IOBPCOKE_02060 1.1e-145 glcU U sugar transport
IOBPCOKE_02061 6e-268 pepC 3.4.22.40 E Peptidase C1-like family
IOBPCOKE_02062 2.4e-115 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
IOBPCOKE_02063 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IOBPCOKE_02064 0.0 S Predicted membrane protein (DUF2207)
IOBPCOKE_02065 2e-214 M Glycosyl hydrolases family 25
IOBPCOKE_02067 2.2e-178 I Carboxylesterase family
IOBPCOKE_02068 6.6e-65 arsC 1.20.4.1 P Belongs to the ArsC family
IOBPCOKE_02069 1.7e-21
IOBPCOKE_02070 1.5e-34 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
IOBPCOKE_02072 6.8e-271 V ABC-type multidrug transport system, ATPase and permease components
IOBPCOKE_02073 2.6e-286 V ABC-type multidrug transport system, ATPase and permease components
IOBPCOKE_02075 4.5e-11 S Protein of unknown function (DUF2922)
IOBPCOKE_02076 1.2e-36 L Single-strand binding protein family
IOBPCOKE_02077 3.7e-44
IOBPCOKE_02080 1.7e-151 glcU U sugar transport
IOBPCOKE_02081 4.5e-48
IOBPCOKE_02082 2.5e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IOBPCOKE_02083 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IOBPCOKE_02084 7e-53 L Replication initiation factor
IOBPCOKE_02085 2.7e-33
IOBPCOKE_02087 7.2e-45
IOBPCOKE_02088 8e-25
IOBPCOKE_02089 1.8e-25
IOBPCOKE_02090 9.5e-16 K transcriptional
IOBPCOKE_02091 1.1e-137 sip L Belongs to the 'phage' integrase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)